Sample records for correlation coefficients exceeding

  1. Zero Pearson coefficient for strongly correlated growing trees

    NASA Astrophysics Data System (ADS)

    Dorogovtsev, S. N.; Ferreira, A. L.; Goltsev, A. V.; Mendes, J. F. F.

    2010-03-01

    We obtained Pearson’s coefficient of strongly correlated recursive networks growing by preferential attachment of every new vertex by m edges. We found that the Pearson coefficient is exactly zero in the infinite network limit for the recursive trees (m=1) . If the number of connections of new vertices exceeds one (m>1) , then the Pearson coefficient in the infinite networks equals zero only when the degree distribution exponent γ does not exceed 4. We calculated the Pearson coefficient for finite networks and observed a slow power-law-like approach to an infinite network limit. Our findings indicate that Pearson’s coefficient strongly depends on size and details of networks, which makes this characteristic virtually useless for quantitative comparison of different networks.

  2. Zero Pearson coefficient for strongly correlated growing trees.

    PubMed

    Dorogovtsev, S N; Ferreira, A L; Goltsev, A V; Mendes, J F F

    2010-03-01

    We obtained Pearson's coefficient of strongly correlated recursive networks growing by preferential attachment of every new vertex by m edges. We found that the Pearson coefficient is exactly zero in the infinite network limit for the recursive trees (m=1). If the number of connections of new vertices exceeds one (m>1), then the Pearson coefficient in the infinite networks equals zero only when the degree distribution exponent gamma does not exceed 4. We calculated the Pearson coefficient for finite networks and observed a slow power-law-like approach to an infinite network limit. Our findings indicate that Pearson's coefficient strongly depends on size and details of networks, which makes this characteristic virtually useless for quantitative comparison of different networks.

  3. [Comparison of atmospheric particulate matter and aerosol optical depth in Beijing City].

    PubMed

    Lin, Hai-Feng; Xin, Jin-Yuan; Zhang, Wen-Yu; Wang, Yue-Si; Liu, Zi-Rui; Chen, Chuan-Lei

    2013-03-01

    The pollution of particulate matter was serious in Beijing City from the synchronous observation of particulate matter mass concentration and aerosol optical characteristics in 2009. The annual mean concentrations of PM2.5 and PM10 were (65 +/- 14) microg x m(-3) and (117 +/- 31) microg x m(-3), respectively, which exceeded the national ambient air quality annual standards to be implemented in 2016. There were 35% and 26% days of 2009 that the daily standards were exceeded. There was a significant correlation between fine particulate (PM2.5) and inhalable particle (PM10), with a correlation coefficient (R) of approximately 0.90 (P < 0.001). PM10 contained a large percentage of PM2.5, with an annual percentage of about 61%. The percentage became much higher from spring to winter, while the correlation between PM2.5 and PM10 became much stronger. The annual mean of AOD (500 nm) and Angstrom exponent were (0.55 +/- 0.1) and (1.12 +/- 0.08), respectively. There were significant correlations between PM2.5, PM10 and AOD in the four seasons and the whole year, and the correlation coefficients were greater than or equal to 0.50. Furthermore, the correlation functions and coefficients had seasonal variations. The correlations were more significant in summer and autumn than in spring and winter. The annual correlation could cover up the seasonal systematic differences. The correlations between AOD revised by Mixed Layer Height and PM2.5 PM10 revised by Relative Humidity became stronger, and the exponential correlations were superior to the linear correlations.

  4. Detection of Unexpected High Correlations between Balance Calibration Loads and Load Residuals

    NASA Technical Reports Server (NTRS)

    Ulbrich, N.; Volden, T.

    2014-01-01

    An algorithm was developed for the assessment of strain-gage balance calibration data that makes it possible to systematically investigate potential sources of unexpected high correlations between calibration load residuals and applied calibration loads. The algorithm investigates correlations on a load series by load series basis. The linear correlation coefficient is used to quantify the correlations. It is computed for all possible pairs of calibration load residuals and applied calibration loads that can be constructed for the given balance calibration data set. An unexpected high correlation between a load residual and a load is detected if three conditions are met: (i) the absolute value of the correlation coefficient of a residual/load pair exceeds 0.95; (ii) the maximum of the absolute values of the residuals of a load series exceeds 0.25 % of the load capacity; (iii) the load component of the load series is intentionally applied. Data from a baseline calibration of a six-component force balance is used to illustrate the application of the detection algorithm to a real-world data set. This analysis also showed that the detection algorithm can identify load alignment errors as long as repeat load series are contained in the balance calibration data set that do not suffer from load alignment problems.

  5. Catching ghosts with a coarse net: use and abuse of spatial sampling data in detecting synchronization

    PubMed Central

    2017-01-01

    Synchronization of population dynamics in different habitats is a frequently observed phenomenon. A common mathematical tool to reveal synchronization is the (cross)correlation coefficient between time courses of values of the population size of a given species where the population size is evaluated from spatial sampling data. The corresponding sampling net or grid is often coarse, i.e. it does not resolve all details of the spatial configuration, and the evaluation error—i.e. the difference between the true value of the population size and its estimated value—can be considerable. We show that this estimation error can make the value of the correlation coefficient very inaccurate or even irrelevant. We consider several population models to show that the value of the correlation coefficient calculated on a coarse sampling grid rarely exceeds 0.5, even if the true value is close to 1, so that the synchronization is effectively lost. We also observe ‘ghost synchronization’ when the correlation coefficient calculated on a coarse sampling grid is close to 1 but in reality the dynamics are not correlated. Finally, we suggest a simple test to check the sampling grid coarseness and hence to distinguish between the true and artifactual values of the correlation coefficient. PMID:28202589

  6. Two-Way Gene Interaction From Microarray Data Based on Correlation Methods.

    PubMed

    Alavi Majd, Hamid; Talebi, Atefeh; Gilany, Kambiz; Khayyer, Nasibeh

    2016-06-01

    Gene networks have generated a massive explosion in the development of high-throughput techniques for monitoring various aspects of gene activity. Networks offer a natural way to model interactions between genes, and extracting gene network information from high-throughput genomic data is an important and difficult task. The purpose of this study is to construct a two-way gene network based on parametric and nonparametric correlation coefficients. The first step in constructing a Gene Co-expression Network is to score all pairs of gene vectors. The second step is to select a score threshold and connect all gene pairs whose scores exceed this value. In the foundation-application study, we constructed two-way gene networks using nonparametric methods, such as Spearman's rank correlation coefficient and Blomqvist's measure, and compared them with Pearson's correlation coefficient. We surveyed six genes of venous thrombosis disease, made a matrix entry representing the score for the corresponding gene pair, and obtained two-way interactions using Pearson's correlation, Spearman's rank correlation, and Blomqvist's coefficient. Finally, these methods were compared with Cytoscape, based on BIND, and Gene Ontology, based on molecular function visual methods; R software version 3.2 and Bioconductor were used to perform these methods. Based on the Pearson and Spearman correlations, the results were the same and were confirmed by Cytoscape and GO visual methods; however, Blomqvist's coefficient was not confirmed by visual methods. Some results of the correlation coefficients are not the same with visualization. The reason may be due to the small number of data.

  7. Correlations of daily flows at streamgages in and near West Virginia, 1930-2011, and streamflow characteristics relevant to the use of index streamgages

    USGS Publications Warehouse

    Messinger, Terence; Paybins, Katherine S.

    2014-01-01

    Correlation of flows at pairs of streamgages were evaluated using a Spearman’s rho correlation coefficient to better identify gages that can be used as index gages to estimate daily flow at ungaged stream sites in West Virginia. Much of West Virginia (77 percent) is within areas where Spearman’s rho for daily streamflow between streamgages on unregulated streams (unregulated streamgages) is greater than 0.9; most withdrawals from ungaged streams for shale gas well hydraulic fracturing are being made in these areas. Most of West Virginia (>99 percent) is within zones where Spearman’s rho between streamgages on unregulated streams is greater than 0.85. Withdrawals for hydraulic fracturing are made from ungaged streams in areas where Spearman’s rho between streamgages on unregulated streams is less than 0.9, but because spatial correlation is partly a function of the density of the streamgaging network, adding or reactivating several streamgages would be likely to result in correlations of 0.90 or higher in these areas. Seasonal differences in the strength and spatial extent of correlations of daily streamflows are great. The strongest correlations among streamgages are for fall, followed by spring, then winter. One possible explanation for the weak correlations for summer may be that precipitation and runoff associated with convective storms affect one basin and miss nearby basins. A comparison of correlation patterns during previously identified climatic periods shows that the strongest correlations occurred during 1963–69, a period of drought, and the weakest during 1970–79, a wet period. The apparent effect of frequent rain during 1970–79 overshadowed streamgage-network density, which was at its historic maximum in West Virginia at that time, so that the extent of areas with high correlation to at least one streamgage was smaller during 1970–79 than during 1963–69. Correlations for 1992 to 2011 were slightly weaker than those for 1963 to 1969. The relation between correlation and distance between basin centroids was determined to be stronger for streamgage pairs in the Ohio River Basin than for pairs in the Atlantic Slope River Basins, which in turn was stronger than the relation between pairs of streamgages split between the two major basins. Quantile regression equations were developed for these three comparisons to estimate the Spearman’s rho correlation coefficient for streamgage pairs using distance between basin centroids as a predictor variable. The equations can be used for streamgage network planning. For the Ohio River Basin, the distance between basin centroids at which 50 percent of streamgage pairs would exceed a Spearman’s rho of 0.95 is 9 miles. The distance between basin centroids at which 50 percent of streamgage pairs would exceed a Spearman’s rho of 0.90 is 25 miles, and the distance at which 50 percent of streamgage pairs would exceed a Spearman’s rho of 0.85 is 48 miles. For the Atlantic Slope River Basins, the distance between basin centroids at which 50 percent of streamgage pairs would exceed a Spearman’s rho of 0.95 is 1 mile. The distance between basin centroids at which 50 percent of streamgage pairs would exceed a Spearman’s rho of 0.90 is 13 miles, and the distance at which 50 percent of streamgage pairs would exceed a Spearman’s rho of 0.85 is 41 miles. For pairs of streamgages split between the two major basins, the regression equation gives a value of 0.84 for the correlation coefficient at zero miles. On maps of correlations, the shape of strongly correlated areas for streamgages in the Ohio River Basin is generally round. In the Valley and Ridge Physiographic Province, which generally coincides with the Atlantic Slope River Basins within the study area, areas strongly correlated with streamgages generally coincide with major valleys.

  8. Relative validity of an FFQ to estimate daily food and nutrient intakes for Chilean adults.

    PubMed

    Dehghan, Mahshid; Martinez, Solange; Zhang, Xiaohe; Seron, Pamela; Lanas, Fernando; Islam, Shofiqul; Merchant, Anwar T

    2013-10-01

    FFQ are commonly used to rank individuals by their food and nutrient intakes in large epidemiological studies. The purpose of the present study was to develop and validate an FFQ to rank individuals participating in an ongoing Prospective Urban and Rural Epidemiological (PURE) study in Chile. An FFQ and four 24 h dietary recalls were completed over 1 year. Pearson correlation coefficients, energy-adjusted and de-attenuated correlations and weighted kappa were computed between the dietary recalls and the FFQ. The level of agreement between the two dietary assessment methods was evaluated by Bland-Altman analysis. Temuco, Chile. Overall, 166 women and men enrolled in the present study. One hundred men and women participated in FFQ development and sixty-six individuals participated in FFQ validation. The FFQ consisted of 109 food items. For nutrients, the crude correlation coefficients between the dietary recalls and FFQ varied from 0.14 (protein) to 0.44 (fat). Energy adjustment and de-attenuation improved correlation coefficients and almost all correlation coefficients exceeded 0.40. Similar correlation coefficients were observed for food groups; the highest de-attenuated energy adjusted correlation coefficient was found for margarine and butter (0.75) and the lowest for potatoes (0.12). The FFQ showed moderate to high agreement for most nutrients and food groups, and can be used to rank individuals based on energy, nutrient and food intakes. The validation study was conducted in a unique setting and indicated that the tool is valid for use by adults in Chile.

  9. Two-Way Gene Interaction From Microarray Data Based on Correlation Methods

    PubMed Central

    Alavi Majd, Hamid; Talebi, Atefeh; Gilany, Kambiz; Khayyer, Nasibeh

    2016-01-01

    Background Gene networks have generated a massive explosion in the development of high-throughput techniques for monitoring various aspects of gene activity. Networks offer a natural way to model interactions between genes, and extracting gene network information from high-throughput genomic data is an important and difficult task. Objectives The purpose of this study is to construct a two-way gene network based on parametric and nonparametric correlation coefficients. The first step in constructing a Gene Co-expression Network is to score all pairs of gene vectors. The second step is to select a score threshold and connect all gene pairs whose scores exceed this value. Materials and Methods In the foundation-application study, we constructed two-way gene networks using nonparametric methods, such as Spearman’s rank correlation coefficient and Blomqvist’s measure, and compared them with Pearson’s correlation coefficient. We surveyed six genes of venous thrombosis disease, made a matrix entry representing the score for the corresponding gene pair, and obtained two-way interactions using Pearson’s correlation, Spearman’s rank correlation, and Blomqvist’s coefficient. Finally, these methods were compared with Cytoscape, based on BIND, and Gene Ontology, based on molecular function visual methods; R software version 3.2 and Bioconductor were used to perform these methods. Results Based on the Pearson and Spearman correlations, the results were the same and were confirmed by Cytoscape and GO visual methods; however, Blomqvist’s coefficient was not confirmed by visual methods. Conclusions Some results of the correlation coefficients are not the same with visualization. The reason may be due to the small number of data. PMID:27621916

  10. The analysis of reliability and validity of the IT-MAIS, MAIS and MUSS.

    PubMed

    Zhong, Yan; Xu, Tianqiu; Dong, Ruijuan; Lyu, Jing; Liu, Bo; Chen, Xueqing

    2017-05-01

    The aim of this study was to investigate the reliability and validity of the Infant-toddler Meaningful Auditory Integration Scale (IT-MAIS), Meaningful Auditory Integration Scale (MAIS), and Meaningful Use of Speech Scale (MUSS). IT-MAIS, MAIS and MUSS were divided into 3 sub dimensions. 300 children with cochlear implants (CI) were included in the investigation. To assess test-retest reliability of these questionnaires, 30 children were selected randomly to be evaluated at a two-week interval indicated that there were no significant changes between test and retest. Furthermore random test analysis by different evaluators was also administered to 30 users. Reliability test: Test-retest reliability of the three scales was proved to be satisfactory. All domains had correlation coefficients that exceeded 0.750(P < 0.01). The Cronbach's α of the three scales and their three domains were greater than 0.700. Reliability between evaluators of the three scales were considered to be satisfactory. All domains had correlation coefficients that exceeded 0.750(P < 0.01). Validity test: The evaluation of content validity by expert review showed the questionnaire had good content validity; The correlation coefficients between the overall scores of the three scales and their three domains were 0.699-0.978(P < 0.01). There were correlations among the three sub-domains but the strength of the correlations was relatively low. There was certain construct validity. IT-MAIS, MAIS, MUSS scales have good reliability and validity, and can be used to measure the outcome for children with cochlear implants hearing and speech evaluation. Copyright © 2017 Elsevier B.V. All rights reserved.

  11. Enhanced thermoelectric power and electronic correlations in RuSe₂

    DOE PAGES

    Wang, Kefeng; Wang, Aifeng; Tomic, A.; ...

    2015-03-03

    We report the electronic structure, electric and thermal transport properties of Ru 1-xIr xSe₂ (x ≤ 0.2). RuSe₂ is a semiconductor that crystallizes in a cubic pyrite unit cell. The Seebeck coefficient of RuSe₂ exceeds -200 μV/K around 730 K. Ir substitution results in the suppression of the resistivity and the Seebeck coefficient, suggesting the removal of the peaks in density of states near the Fermi level. Ru 0.8Ir 0.2Se₂ shows a semiconductor-metal crossover at about 30 K. The magnetic field restores the semiconducting behavior. Our results indicate the importance of the electronic correlations in enhanced thermoelectricity of RuSb₂.

  12. Reliability of pulse waveform separation analysis: effects of posture and fasting.

    PubMed

    Stoner, Lee; Credeur, Daniel; Fryer, Simon; Faulkner, James; Lambrick, Danielle; Gibbs, Bethany Barone

    2017-03-01

    Oscillometric pulse wave analysis devices enable, with relative simplicity and objectivity, the measurement of central hemodynamic parameters. The important parameters are central blood pressures and indices of arterial wave reflection, including wave separation analysis (backward pressure component Pb and reflection magnitude). This study sought to determine whether the measurement precision (between-day reliability) of Pb and reflection magnitude: exceeds the criterion for acceptable reliability; and is affected by posture (supine, seated) and fasting state. Twenty healthy adults (50% female, 27.9 years, 24.2 kg/m) were tested on six different mornings: 3 days fasted, 3 days nonfasted condition. On each occasion, participants were tested in supine and seated postures. Oscillometric pressure waveforms were recorded on the left upper arm. The criterion intra-class correlation coefficient value of 0.75 was exceeded for Pb (0.76) and reflection magnitude (0.77) when participants were assessed under the combined supine-fasted condition. The intra-class correlation coefficient was lowest for Pb in seated-nonfasted condition (0.57), and lowest for reflection magnitude in the seated-fasted condition (0.56). For Pb, the smallest detectible change that must be exceeded in order for a significant change to occur in an individual was 2.5 mmHg, and for reflection magnitude, the smallest detectable change was 8.5%. Assessments of Pb and reflection magnitude are as follows: exceed the criterion for acceptable reliability; and are most reliable when participants are fasted in a supine position. The demonstrated reliability suggests sufficient precision to detect clinically meaningful changes in reflection magnitude and Pb.

  13. The Persian Version of the "Life Satisfaction Scale": Construct Validity and Test-Re-Test Reliability among Iranian Older Adults.

    PubMed

    Moghadam, Manije; Salavati, Mahyar; Sahaf, Robab; Rassouli, Maryam; Moghadam, Mojgan; Kamrani, Ahmad Ali Akbari

    2018-03-01

    After forward-backward translation, the LSS was administered to 334 Persian speaking, cognitively healthy elderly aged 60 years and over recruited through convenience sampling. To analyze the validity of the model's constructs and the relationships between the constructs, a confirmatory factor analysis followed by PLS analysis was performed. The Construct validity was further investigated by calculating the correlations between the LSS and the "Short Form Health Survey" (SF-36) subscales measuring similar and dissimilar constructs. The LSS was re-administered to 50 participants a month later to assess the reliability. For the eight-factor model of the life satisfaction construct, adequate goodness of fit between the hypothesized model and the model derived from the sample data was attained (positive and statistically significant beta coefficients, good R-squares and acceptable GoF). Construct validity was supported by convergent and discriminant validity, and correlations between the LSS and SF-36 subscales. Minimum Intraclass Correlation Coefficient level of 0.60 was exceeded by all subscales. Minimum level of reliability indices (Cronbach's α, composite reliability and indicator reliability) was exceeded by all subscales. The Persian-version of the Life Satisfaction Scale is a reliable and valid instrument, with psychometric properties which are consistent with the original version.

  14. Validation of multi-angle imaging spectroradiometer aerosol products in China

    Treesearch

    J. Liu; X. Xia; Z. Li; P. Wang; M. Min; WeiMin Hao; Y. Wang; J. Xin; X. Li; Y. Zheng; Z. Chen

    2010-01-01

    Based on AErosol RObotic NETwork and Chinese Sun Hazemeter Network data, the Multi-angle Imaging SpectroRadiometer (MISR) level 2 aerosol optical depth (AOD) products are evaluated in China. The MISR retrievals depict well the temporal aerosol trend in China with correlation coefficients exceeding 0.8 except for stations located in northeast China and at the...

  15. American Orthopaedic Foot and Ankle Society ankle-hindfoot scale: A cross-cultural adaptation and validation study from Iran.

    PubMed

    Vosoughi, Amir Reza; Roustaei, Narges; Mahdaviazad, Hamideh

    2018-06-01

    The use of valid and reliable outcome rating scales is essential for evaluating the result of different treatments and interventions. The purposes of this study were to translate and culturally adapt the American Orthopaedic Foot and Ankle Society ankle-hindfoot scale (AOFAS-AHFS) into Persian languages and evaluate its psychometric properties. Forward-backward translation and cultural adaptation method were used to develop Persian version of AOFAS-AHFS. From March to July 2016, one hundred consecutive patients with ankle and hindfoot injuries were included. Internal consistency and reproducibility were evaluated using Cronbach's alpha, Spearman's rank correlation coefficient and Intraclass correlation coefficient (ICC) respectively. Construct validity reported which compare the outcome rating scale measurements with Short Form-36 (SF-36), also convergent and discriminant validity evaluated using Spearman's rank correlation coefficient. Mean age (SD) of the patients was 41.95±13.45years. Cronbach's α coefficient, Spearman's rho and ICC values were 0.71, 0.89 and 0.90 respectively. Total score of AOFAS-AHFS and SF-36 domains has a correlation ranged between 0.17-0.55. Spearman's rank correlation coefficient of 0.4 was exceeded by all items with the exception of stability. The Spearman's rank correlation between each item in functional subscales with its own subscales was higher than the correlation between these items and other subscales. Persian version of AOFAS-AHFS provides additional reliable and valid instrument which can be used to assess broad range of patients with foot and ankle disorders that speaking in Persian. However, it seems that the original version of AOFAS-AHFS needs some revisions. Copyright © 2017 European Foot and Ankle Society. Published by Elsevier Ltd. All rights reserved.

  16. Estimates of Intraclass Correlation Coefficients from Longitudinal Group-Randomized Trials of Adolescent HIV/STI/Pregnancy Prevention Programs

    ERIC Educational Resources Information Center

    Glassman, Jill R.; Potter, Susan C.; Baumler, Elizabeth R.; Coyle, Karin K.

    2015-01-01

    Introduction: Group-randomized trials (GRTs) are one of the most rigorous methods for evaluating the effectiveness of group-based health risk prevention programs. Efficiently designing GRTs with a sample size that is sufficient for meeting the trial's power and precision goals while not wasting resources exceeding them requires estimates of the…

  17. [Correlation between gaseous exchange rate, body temperature, and mitochondrial protein content in the liver of mice].

    PubMed

    Muradian, Kh K; Utko, N O; Mozzhukhina, T H; Pishel', I M; Litoshenko, O Ia; Bezrukov, V V; Fraĭfel'd, V E

    2002-01-01

    Correlative and regressive relations between the gaseous exchange, thermoregulation and mitochondrial protein content were analyzed by two- and three-dimensional statistics in mice. It has been shown that the pair wise linear methods of analysis did not reveal any significant correlation between the parameters under exploration. However, it became evident at three-dimensional and non-linear plotting for which the coefficients of multivariable correlation reached and even exceeded 0.7-0.8. The calculations based on partial differentiation of the multivariable regression equations allow to conclude that at certain values of VO2, VCO2 and body temperature negative relations between the systems of gaseous exchange and thermoregulation become dominating.

  18. Ultrasonographic assessment of splenic volume and its correlation with body parameters in a Jordanian population.

    PubMed

    Badran, Darwish H; Kalbouneh, Heba M; Al-Hadidi, Maher T; Shatarat, Amjad T; Tarawneh, Emad S; Hadidy, Azmy M; Mahafza, Waleed S

    2015-08-01

    To estimate normal linear dimensions and volume of spleen in Jordanians using ultrasonography, and to correlate splenic volume with age and body parameters: height, weight, body surface area (BSA), and body mass index (BMI). A prospective pilot study was conducted on 205 volunteers (115 males and 90 females) not known to have any conditions likely to be associated with splenomegaly. The study was performed at the Radiology Department, Jordanian University Hospital, Amman, Jordan, between December 2013 and August 2014. All linear dimensions of spleen were measured, and splenic volume (index) was calculated using the standard prolate ellipsoid formula (length × width × depth × 0.523). The splenic volume was then analyzed with age and body parameters using the Pearson's correlation coefficient. The mean (± SD) splenic dimensions were 10.72±1.37 cm in length, 7.40±1.52 cm in width, 4.40±1.47 cm in depth, and 184.15±79.56 cm3 in volume. Men had larger spleens than women (p less than 0.0001). Age had no significant effect on spleen volume (r=0.11, p=0.12). There was a significant moderate positive correlation (p less than 0.0001), using Pearson's correlation coefficient, between the spleen volume, and other parameters (height, weight, BSA, and BMI), with correlation coefficients exceeding 0.3. A local reference of spleen dimensions was established with a different range of values reported previously.

  19. Testing a single regression coefficient in high dimensional linear models

    PubMed Central

    Zhong, Ping-Shou; Li, Runze; Wang, Hansheng; Tsai, Chih-Ling

    2017-01-01

    In linear regression models with high dimensional data, the classical z-test (or t-test) for testing the significance of each single regression coefficient is no longer applicable. This is mainly because the number of covariates exceeds the sample size. In this paper, we propose a simple and novel alternative by introducing the Correlated Predictors Screening (CPS) method to control for predictors that are highly correlated with the target covariate. Accordingly, the classical ordinary least squares approach can be employed to estimate the regression coefficient associated with the target covariate. In addition, we demonstrate that the resulting estimator is consistent and asymptotically normal even if the random errors are heteroscedastic. This enables us to apply the z-test to assess the significance of each covariate. Based on the p-value obtained from testing the significance of each covariate, we further conduct multiple hypothesis testing by controlling the false discovery rate at the nominal level. Then, we show that the multiple hypothesis testing achieves consistent model selection. Simulation studies and empirical examples are presented to illustrate the finite sample performance and the usefulness of the proposed method, respectively. PMID:28663668

  20. Testing a single regression coefficient in high dimensional linear models.

    PubMed

    Lan, Wei; Zhong, Ping-Shou; Li, Runze; Wang, Hansheng; Tsai, Chih-Ling

    2016-11-01

    In linear regression models with high dimensional data, the classical z -test (or t -test) for testing the significance of each single regression coefficient is no longer applicable. This is mainly because the number of covariates exceeds the sample size. In this paper, we propose a simple and novel alternative by introducing the Correlated Predictors Screening (CPS) method to control for predictors that are highly correlated with the target covariate. Accordingly, the classical ordinary least squares approach can be employed to estimate the regression coefficient associated with the target covariate. In addition, we demonstrate that the resulting estimator is consistent and asymptotically normal even if the random errors are heteroscedastic. This enables us to apply the z -test to assess the significance of each covariate. Based on the p -value obtained from testing the significance of each covariate, we further conduct multiple hypothesis testing by controlling the false discovery rate at the nominal level. Then, we show that the multiple hypothesis testing achieves consistent model selection. Simulation studies and empirical examples are presented to illustrate the finite sample performance and the usefulness of the proposed method, respectively.

  1. [Study on the secular trend of road traffic injuries and its influencing factors in China].

    PubMed

    Chi, Gui-bo; Wang, Sheng-Yong

    2007-02-01

    To analyze and summarize the secular trend and influencing factors of road traffic injuries(RTI) in China, so as to provide evidence for the management of traffic safety. Indexes as fatalities per 10,000 vehicles, fatalities per 100,000 population, fatalities per 10,000 kilometers, motorization(number of vehicles per 1000 population) and mortal coefficient were used. Clustering analysis and ranking correlation were used to analyze the relative factors. The number of casualties of RTI had doubled every decade before the year of 2000. One hundred thousand people were killed in RTI every year since 2000. Facts as: Gross National Product(GNP) of China exceeded 1000 USD in 2002, number of motor vehicles reached 1.3 million in 2005, had both influenced the rates of road traffic fatality, mileage fatality and mortal coefficient which causing them to drop since 2002. In China, RTI happened in the underdeveloped districts in the western part of the country including Tibet, Ningxia, Xinjiang, Qinghai, and in some coastal areas as Zhejiang and Guangdong provinces. Men seemed to be more at risk than women in RTI, and accounted for three-quarters of the victims. Majority of fatalities happened in 21-50 year olds and the fatalities among those over 65 year olds had risen every year. The vulnerable populations in road-user category were pedestrians, passengers, motorcyclists and bicyclists. Under most situations, drivers were responsible for RTI and over half of them were professionals. Bad behaviors were the major causes of RTI, including exceeding the speed limit, handle misfeasance, breaking traffic rules and regulation, having taken alcohol or driving with fatigue etc. Exceeding the speed limit was the most risky factor which causing 75% of the RTI and the traffic deaths increased between 2002 to 2004. A positive correlation was discovered between population fatality rate and the factors as the number of vehicles, volume of road haulage, volume of passengers and the degree of highway etc. with correlation coefficients as r1 = 0.986, r2 = 0.986, r3 = 0.987, r4 = 0.985, P = 0.001, respectively. Since 1951, the population fatality rate of RTI had been going up continuously until it began to fall in 2003.

  2. Reliability and validity of the Chinese mandarin version of PedsQL™ 3.0 transplant module.

    PubMed

    Chang, Ying; Luo, Yanhui; Zhou, Yuchen; Wang, Ruixin; Song, Na; Zhu, Guanghua; Wang, Bin; Qin, Maoquan; Yang, Jun; Sun, Yuan; Li, Chunfu; Zhou, Xuan

    2016-10-05

    Long-term health-related quality of life (HRQoL) of pediatric patients after hematopoietic stem cell transplantation (HSCT) is increasingly studied worldwide. However, few studies have been performed in China, where no uniform scale is available; the PedsQL™ Cancer Module 3.0 Chinese Mandarin version has been used to evaluate HRQoL of patients after HSCT in China. This study aimed to assess the reliability and validity of the Chinese Mandarin version of PedsQL™ 3.0 Transplant Module. Patients between 2 and 18 years old, who underwent HSCT from January 2006 to June 2014, were recruited in Beijing Children's Hospital affiliated to Capital Medical University, the First Affiliated Hospital of Southern Medical University and Beijing Daopei Hospital. 207 parent reports and 182 child self-reports of the PedsQL™ 3.0 Transplant Module Chinese Mandarin version were assigned, of which 362 were returned. No missing item response was observed in the returned reports. Cronbach's alpha coefficient exceeded 0.7 in total scale and every dimension. The intraclass correlation coefficient exceeded 0.8 in all dimensions of child self-reports and parent reports. Spearman's rank correlation coefficients of items and their respective dimensions were 0.6-0.94 in parent reports, and 0.62-0.93 in child self-reports, while a weak association was found between the items and other dimensions. Exploratory factor analysis indicated a good extraction effect, and construct validity of the scale was >60 %. The Chinese Mandarin version of PedsQL™ 3.0 Transplant Module has good feasibility, reliability and validity. Its use may help improve the HRQoL of children after HSCT in China.

  3. Rhenium in ores of the Mikheevskoe porphyry Cu-Mo deposit, South Urals

    NASA Astrophysics Data System (ADS)

    Plotinskaya, O. Yu.; Grabezhev, A. I.; Seltmann, R.

    2015-03-01

    The distribution of Re in ores of the Mikheevskoe Mo-Cu deposit in the South Urals is studied. It is established that the grade of Re in the ores usually does not exceed 0.5 g/t. A positive correlation between concentrations of Re and Mo (correlation coefficient 0.94), and Re and Cu (correlation coefficient 0.52) is found. EMPA of individual flakes of molybdenite showed that a Re content higher than the detection limit has been measured in most flakes studied, as a rule as high as 0.4-0.5 wt %, but occasionally reaching 1.34 wt %. Re within flakes of molybdenite is irregularly distributed. Patchy, linear, and concentric-zoned patterns of zones with elevated Re content (usually 0.5-1 wt % Re, sometimes higher) are found against the lower content (up to 0.2 wt % Re) that is regularly distributed within the flake. Later hydrothermal processes and mechanical deformation of flakes result in epigenetic Re redistribution in molybdenite that leads to homogenization of molybdenite composition and smoothing of primary pattern, or removal of Re from molybdenite.

  4. Tests of Mediation: Paradoxical Decline in Statistical Power as a Function of Mediator Collinearity

    PubMed Central

    Beasley, T. Mark

    2013-01-01

    Increasing the correlation between the independent variable and the mediator (a coefficient) increases the effect size (ab) for mediation analysis; however, increasing a by definition increases collinearity in mediation models. As a result, the standard error of product tests increase. The variance inflation due to increases in a at some point outweighs the increase of the effect size (ab) and results in a loss of statistical power. This phenomenon also occurs with nonparametric bootstrapping approaches because the variance of the bootstrap distribution of ab approximates the variance expected from normal theory. Both variances increase dramatically when a exceeds the b coefficient, thus explaining the power decline with increases in a. Implications for statistical analysis and applied researchers are discussed. PMID:24954952

  5. Aerodynamic Heating Computations for Projectiles. Volume 1. In-Depth Heat Conduction Modifications to the ABRES Shape Change Code (BRLASCC)

    DTIC Science & Technology

    1984-06-01

    preceding the corresponding pressure group of the surface thermochemistry deck as described below. The temperature entries within each section must be... pressure group the transfer coefficient values will be ordered. Within each transfer coefficient section, ablation rate entries need not he ordered in any...may not exceed 5 (and may be only I); the number of transfer coefficient values in each pressure group may not exceed 5 but may be only 1. If no

  6. Characterization of criteria air pollutants in Beijing during 2014-2015.

    PubMed

    Guo, Hao; Wang, Yungang; Zhang, Hongliang

    2017-04-01

    One year-long criteria air pollutants data collected in Beijing were analyzed in this paper, which can support the research on formation, transport and human health effects of air pollutants. This is the first time to study the spatial and temporal variations of criteria pollutants in Beijing using hourly observational data from 12 sites between June 2014 and May 2015 released by the Ministry of Environmental Protection (MEP) of China. Beijing is facing tremendous air pollution as the daily averaged PM 2.5 (particulate matter with aerodynamic diameter less than 2.5µm) concentrations in all sites exceeding the Chinese Ambient Air Quality Standards (CAAQS) Grade I & II standards (15 and 35µg/m 3 ). Slightly differences in PM 2.5 and ozone (O 3 ) were observed between sites at the urban and rural areas. Pearson correlation coefficients show that most pollutants are temporally correlated in Beijing except for O 3 . The coefficients of divergence (COD) indicate that PM 2.5 is associated at most sites with only one rural site (Dingling) having observable difference and one site may be insufficient for monitoring surrounding area. The 8h peak O 3 (O 3 -8h) also correlates at different sites but with one urban site (Haidianquwanliu) different from others. In addition, an extreme PM 2.5 event (hourly average concentration exceeding 300μg/m 3 for ~40h) was examined with the consideration of meteorological conditions. Southerly wind with low speed and high relative humidity allow the accumulation of pollutants while northerly wind with high speed and low relative humidity result in good air quality. Copyright © 2017 Elsevier Inc. All rights reserved.

  7. A Spanish version of the Skin Cancer Index: a questionnaire for measuring quality of life in patients with cervicofacial nonmelanoma skin cancer.

    PubMed

    de Troya-Martín, M; Rivas-Ruiz, F; Blázquez-Sánchez, N; Fernández-Canedo, I; Aguilar-Bernier, M; Repiso-Jiménez, J B; Toribio-Montero, J C; Jones-Caballero, M; Rhee, J

    2015-01-01

    The Skin Cancer Index (SCI) is the first specific patient-reported outcome measure for patients with cervicofacial nonmelanoma skin cancer. To date, only the original English version has been published. To develop a Spanish version of the SCI that is semantically and linguistically equivalent to the original, and to evaluate its measurement properties in this different cultural environment. A cross-sectional study was conducted of the cultural adaptation and empirical validation of the questionnaire, analysing the psychometric properties of the new index at different stages. Of 440 patients recruited to the study, 431 (95%) completed the Spanish version of the SCI questionnaire, in a mean time of 6·3 min (SD 2·9). Factor analysis of the scale revealed commonality and loading values of < 0·5 for three of the 15 items. The remaining 12 items converged into two components: appearance/social aspects (seven items) and emotional aspects (five items). Both domains presented a high level of internal consistency, with Cronbach's alpha values above 0·8. The convergent-discriminant validity analysis produced correlations higher than 0·3 for the mental component of the Short Form Health Survey-12v2 Health Questionnaire (correlation coefficient 0·39) and the Dermatology Quality of Life Index (correlation coefficient -0·30). In the test-retest, nine of the 12 items produced a weighted kappa value exceeding 0·4, and for the remaining three items, the absolute agreement percentage exceeded 60%. The Spanish version of the SCI quality of life scale has been satisfactorily adapted and validated for use in Spanish-speaking countries and populations. © 2014 British Association of Dermatologists.

  8. Effective record length for the T-year event

    USGS Publications Warehouse

    Tasker, Gary D.

    1983-01-01

    The effect of serial dependence on the reliability of an estimate of the T-yr. event is of importance in hydrology because design decisions are based upon the estimate. In this paper the reliability of estimates of the T-yr. event from two common distributions is given as a function of number of observations and lag-one serial correlation coefficient for T = 2, 10, 20, 50, and 100 yr. A lag-one autoregressive model is assumed with either a normal or Pearson Type-III disturbance term. Results indicate that, if observations are serially correlated, the effective record length should be used to estimate the discharge associated with the expected exceedance probability. ?? 1983.

  9. The design of control system of livestock feeding processing

    NASA Astrophysics Data System (ADS)

    Sihombing, Juna; Napitupulu, Humala L.; Hidayati, Juliza

    2018-03-01

    PT. XYZ is a company that produces animal feed. One type of animal feed produced is 105 ISA P. In carrying out its production process, PT. XYZ faces the problem of rejected feed amounts during 2014 to June 2015 due to the amount of animal feed that exceeds the standard feed quality of 13% of moisture content and 3% for ash content. Therefore, the researchers analyzed the relationship between factors affecting the quality and extent of damage by using regression and correlation and determine the optimum value of each processing process. Analysis results found that variables affecting product quality are mixing time, steam conditioning temperature and cooling time. The most dominant variable affecting the product moisture content is mixing time with the correlation coefficient of (0.7959) and the most dominant variable affecting the ash content of the product during the processing is mixing time with the correlation coefficient of (0.8541). The design of the proposed product processing control is to run the product processing process with mixing time 235 seconds, steam conditioning temperature 87 0C and cooling time 192 seconds. Product quality 105 ISA P obtained by using this design is with 12.16% moisture content and ash content of 2.59%.

  10. Validation and cultural adaptation of a German version of the Physicians' Reactions to Uncertainty scales

    PubMed Central

    Schneider, Antonius; Szecsenyi, Joachim; Barie, Stefan; Joest, Katharina; Rosemann, Thomas

    2007-01-01

    Background The aim of the study was to examine the validity of a translated and culturally adapted version of the Physicians' Reaction to Uncertainty scales (PRU) in primary care physicians. Methods In a structured process, the original questionnaire was translated, culturally adapted and assessed after administering it to 93 GPs. Test-retest reliability was tested by sending the questionnaire to the GPs again after two weeks. Results The principal factor analysis confirmed the postulated four-factor structure underlying the 15 items. In contrast to the original version, item 5 achieved a higher loading on the 'concern about bad outcomes' scale. Consequently, we rearranged the scales. Good item-scale correlations were obtained, with Pearson's correlation coefficient ranging from 0.56–0.84. As regards the item-discriminant validity between the scales 'anxiety due to uncertainty' and 'concern about bad outcomes', partially high correlations (Pearson's correlation coefficient 0.02–0.69; p < 0.001) were found, indicating an overlap between both constructs. The assessment of internal consistency revealed satisfactory values; Cronbach's alpha of the rearranged version was 0.86 or higher for all scales. Test-retest-reliability, assessed by means of the intraclass-correlation-coefficient (ICC), exceeded 0.84, except for the 'reluctance to disclose mistakes to physicians' scale (ICC = 0.66). In this scale, some substantial floor effects occurred, with 29.3% of answers showing the lowest possible value. Conclusion Dealing with uncertainty is an important issue in daily practice. The psychometric properties of the rearranged German version of the PRU are satisfying. The revealed floor effects do not limit the significance of the questionnaire. Thus, the German version of the PRU could contribute to the further evaluation of the impact of uncertainty in primary care physicians. PMID:17562018

  11. Development, linguistic and clinimetric validation of the WOMAC VA3.01 Bangla for Bangladesh Index.

    PubMed

    Rabbani, M G; Haq, S A; Bellamy, N; Islam, M N; Choudhury, M R; Naheed, A; Ahmed, S; Shahin, A

    2015-06-01

    The aim of this study was to develop and to validate a Bengali version of the Western Ontario and McMaster Osteoarthritis (WOMAC) index in Bangladesh. The WOMAC was translated into the local language of Bangladesh (Bengali) and adapted in the local sociocultural context, following the standard guidelines by Beaton et al. Content validity of the preliminary Bengali version was assessed by using the index of content validity (ICV) and floor and ceiling effects. Patients were assessed at the Department of Rheumatology of Bangabandhu Sheikh Mujib Medical University and were diagnosed to have knee OA by American College of Rheumatology criteria and recruited according to the requirements of the validation study. Convergent and divergent validity were measured by comparing with Health Assessment Questionnaire (HAQ) and the Short Form-36 (SF-36), and internal consistency was assessed using Cronbach's alpha coefficient. The questionnaire was readministered to 40 patients within a week for assessing reliability by using intra-class correlation coefficient (ICC) and Spearman's rank correlation coefficient. In addition, factor analysis of Bengali WOMAC questionnaire was performed to examine the number of factors influencing a common set of items. A Bengali version was developed with changes in three items to suit local practices. The ICV of the content validity was 1 for all items. The Bengali WOMAC had similar construct validity when compared to the HAQ (ρ 0.74, n = 70) and SF-36 bodily pain and physical functioning. It had dissimilar construct validity to SF-36 mental health domain except WOMAC pain. Factor analysis revealed five factors with eigenvalues of more than 1.0. Cronbach's alpha and ICC exceeded 0.7 in all domains. In the test-retest reliability testing, Spearman's ρ for all items exceeded 0.4 (n = 40). This study has demonstrated that the Bengali version of WOMAC is a valid tool for assessing quality of life of patients with knee osteoarthritis in Bangladesh and is reliable.

  12. Examination of the Armagh Observatory Annual Mean Temperature Record, 1844-2004

    NASA Technical Reports Server (NTRS)

    Wilson, Robert M.; Hathaway, David H.

    2006-01-01

    The long-term annual mean temperature record (1844-2004) of the Armagh Observatory (Armagh, Northern Ireland, United Kingdom) is examined for evidence of systematic variation, in particular, as related to solar/geomagnetic forcing and secular variation. Indeed, both are apparent in the temperature record. Moving averages for 10 years of temperature are found to highly correlate against both 10-year moving averages of the aa-geomagnetic index and sunspot number, having correlation coefficients of approx. 0.7, inferring that nearly half the variance in the 10-year moving average of temperature can be explained by solar/geomagnetic forcing. The residuals appear episodic in nature, with cooling seen in the 1880s and again near 1980. Seven of the last 10 years of the temperature record has exceeded 10 C, unprecedented in the overall record. Variation of sunspot cyclic averages and 2-cycle moving averages of temperature strongly associate with similar averages for the solar/geomagnetic cycle, with the residuals displaying an apparent 9-cycle variation and a steep rise in temperature associated with cycle 23. Hale cycle averages of temperature for even-odd pairs of sunspot cycles correlate against similar averages for the solar/geomagnetic cycle and, especially, against the length of the Hale cycle. Indications are that annual mean temperature will likely exceed 10 C over the next decade.

  13. Determination of flavonoids in plant material by HPLC with diode-array and electro-array detections.

    PubMed

    Mattila, P; Astola, J; Kumpulainen, J

    2000-12-01

    A high-performance liquid chromatographic (HPLC) method with in-line connected diode-array (DAD) and electro-array (EC) detection to identify and quantify 17 flavonoids in plant-derived foods is described. Catechins were extracted from the samples using ethyl acetate, and quantification of these compounds was performed with the EC detector. Other flavonoids were quantified with DAD after acid hydrolysis. The methods developed were effective for the determination of catechins and other flavonoids in plant-derived foods. Responses of the detection systems were linear within the range evaluated, 20-200 ng/injection (DAD) and 20-100 ng/injection (EC), with correlation coefficients exceeding 0.999. Coefficient of variation was under 10.5%, and recoveries of flavonoids ranged from 70 to 124%. Purity of the flavonoid peaks was confirmed by combining the spectral and voltammetric data.

  14. Statistical theory of diffusion in concentrated bcc and fcc alloys and concentration dependencies of diffusion coefficients in bcc alloys FeCu, FeMn, FeNi, and FeCr

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Vaks, V. G.; Khromov, K. Yu., E-mail: khromov-ky@nrcki.ru; Pankratov, I. R.

    2016-07-15

    The statistical theory of diffusion in concentrated bcc and fcc alloys with arbitrary pairwise interatomic interactions based on the master equation approach is developed. Vacancy–atom correlations are described using both the second-shell-jump and the nearest-neighbor-jump approximations which are shown to be usually sufficiently accurate. General expressions for Onsager coefficients in terms of microscopic interatomic interactions and some statistical averages are given. Both the analytical kinetic mean-field and the Monte Carlo methods for finding these averages are described. The theory developed is used to describe sharp concentration dependencies of diffusion coefficients in several iron-based alloy systems. For the bcc alloys FeCu,more » FeMn, and FeNi, we predict the notable increase of the iron self-diffusion coefficient with solute concentration c, up to several times, even though values of c possible for these alloys do not exceed some percent. For the bcc alloys FeCr at high temperatures T ≳ 1400 K, we show that the very strong and peculiar concentration dependencies of both tracer and chemical diffusion coefficients observed in these alloys can be naturally explained by the theory, without invoking exotic models discussed earlier.« less

  15. Development, reproducibility and validity of the food frequency questionnaire in the Poland arm of the Prospective Urban and Rural Epidemiological (PURE) study.

    PubMed

    Dehghan, M; Ilow, R; Zatonska, K; Szuba, A; Zhang, X; Mente, A; Regulska-Ilow, B

    2012-06-01

    A food frequency questionnaire (FFQ) is the most commonly used method in large epidemiological studies. The validation of an FFQ is essential for specific populations because foods are culture-dependent. The present study aimed to develop an FFQ and evaluate its validity and reproducibility in estimating the intake of nutrients in urban and rural areas of Poland. Adult participants (n = 146) in the Polish arm of the ongoing Prospective Urban and Rural Epidemiological (PURE) study completed FFQs on two occasions, as well as four 24-h dietary recalls (DRs) during a 12-month period. Correlation coefficients (r) and de-attenuated correlation coefficients between dietary recalls and both FFQs were calculated for selected macro- and micronutrients. Agreement between the two methods was evaluated by classification into quartiles and the Bland-Altman method. Reproducibility was assessed by the intra-class correlation coefficient (ICC). The final food list contained 134 food items. For urban participants, FFQ2 generally underestimated energy, protein and fat compared to the FFQ1 and mean of DRs. In rural areas, compared to DRs, both FFQs overestimated energy and macronutrients. For both urban and rural settings, de-attenuated correlation exceeded 0.4 for almost all nutrients and the exact agreement in quartile categorisation was >66%. When assessing repeatability, ICC varied from 0.39-0.63 in an urban setting and 0.19-0.45 in a rural setting. This 134-item FFQ has good validity and reproducibility in relation to the reference method and can be used to rank individuals based on their macro- and micronutrient intake. © 2012 The Authors. Journal of Human Nutrition and Dietetics © 2012 The British Dietetic Association Ltd.

  16. Advanced and innovative wind energy concept development: Dynamic inducer system

    NASA Astrophysics Data System (ADS)

    Lissaman, P. B. S.; Zalay, A. D.; Hibbs, B. H.

    1981-05-01

    The performance benefits of the dynamic inducer tip vane system was demonstrated Tow-tests conducted on a three-bladed, 3.6-meter diameter rotor show that a dynamic inducer can achieve a power coefficient (based pon power blade swept area) of 0.5, which exceeds that of a plain rotor by about 35%. Wind tunnel tests conducted on a one-third scale model of the dynamic inducer achieved a power coefficient of 0.62 which exceeded that of a plain rotor by about 70%. The dynamic inducer substantially improves the performance of conventional rotors and indications are that higher power coefficients can be achieved through additional aerodynamic optimization.

  17. Super-resolution study of polymer mobility fluctuations near c*.

    PubMed

    King, John T; Yu, Changqian; Wilson, William L; Granick, Steve

    2014-09-23

    Nanoscale dynamic heterogeneities in synthetic polymer solutions are detected using super-resolution optical microscopy. To this end, we map concentration fluctuations in polystyrene-toluene solutions with spatial resolution below the diffraction limit, focusing on critical fluctuations near the polymer overlap concentration, c*. Two-photon super-resolution microscopy was adapted to be applicable in an organic solvent, and a home-built STED-FCS system with stimulated emission depletion (STED) was used to perform fluorescence correlation spectroscopy (FCS). The polystyrene serving as the tracer probe (670 kg mol(-1), radius of gyration RG ≈ 35 nm, end-labeled with a bodipy derivative chromophore) was dissolved in toluene at room temperature (good solvent) and mixed with matrix polystyrene (3,840 kg mol(-1), RG ≈ 97 nm, Mw/Mn = 1.04) whose concentration was varied from dilute to more than 10c*. Whereas for dilute solutions the intensity-intensity correlation function follows a single diffusion process, it splits starting at c* to imply an additional relaxation process provided that the experimental focal area does not greatly exceed the polymer blob size. We identify the slower mode as self-diffusion and the increasingly rapid mode as correlated segment fluctuations that reflect the cooperative diffusion coefficient, Dcoop. These real-space measurements find quantitative agreement between correlation lengths inferred from dynamic measurements and those from determining the limit below which diffusion coefficients are independent of spot size. This study is considered to illustrate the potential of importing into polymer science the techniques of super-resolution imaging.

  18. Malaria's indirect contribution to all-cause mortality in the Andaman Islands during the colonial era.

    PubMed

    Shanks, G Dennis; Hay, Simon I; Bradley, David J

    2008-09-01

    Malaria has a substantial secondary effect on other causes of mortality. From the 19th century, malaria epidemics in the Andaman Islands' penal colony were initiated by the brackish swamp-breeding malaria vector Anopheles sundaicus and fuelled by the importation of new prisoners. Malaria was a major determinant of the highly variable all-cause mortality rate (correlation coefficient r(2)=0.60, n=68, p<0.0001) from 1872 to 1939. Directly attributed malaria mortality based on post-mortem examinations rarely exceeded one-fifth of total mortality. Infectious diseases such as pneumonia, tuberculosis, dysentery, and diarrhoea, which combined with malaria made up the majority of all-cause mortality, were positively correlated with malaria incidence over several decades. Deaths secondary to malaria (indirect malaria mortality) were at least as great as mortality directly attributed to malaria infections.

  19. Comparison of marginal bleeding using a periodontal probe or an interdental brush as indicators of gingivitis.

    PubMed

    Hofer, D; Sahrmann, P; Attin, T; Schmidlin, P R

    2011-08-01

    To compare the use of interdental brushes to a periodontal probe in assessing marginal bleeding, in natural gingivitis. Sixty-four consecutive volunteers presenting with gingival inflammation were recruited at their semi-annual recall appointments for this study. All had ≥50% papillary height and no pocketing that exceeded 4 mm. Contra-lateral quadrants (1 & 3 or 2 & 4) were randomly tested for bleeding with one pass-through with an interdental brush or with a periodontal probe inserted 2 mm into the gingival sulcus. The presence or absence of both bleeding and plaque were then recorded. Correlation coefficients were calculated for the interdental brushes and the periodontal probe, and the plaque and bleeding scores. The periodontal probe and the interdental brushes showed mean average bleeding scores of 47.39% and 45.74% respectively. The correlation coefficient for the two methods was 0.73 (P < 0.0001). No correlation between plaque and bleeding was found. Interdental brushes can be considered a valid alternative to a periodontal probe in assessing marginal bleeding in gingivitis patients. An interdental brush, sized correctly for each interdental space, is easy to handle, atraumatic to the papillae and will allow gingivitis patients to monitor their own progress, while at the same time performing a beneficial oral hygiene procedure and removing any interdental plaque present. © 2010 John Wiley & Sons A/S.

  20. Validation of the Japanese version of the Pediatric Quality of Life Inventory (PedsQL) Cancer Module.

    PubMed

    Tsuji, Naoko; Kakee, Naoko; Ishida, Yasushi; Asami, Keiko; Tabuchi, Ken; Nakadate, Hisaya; Iwai, Tsuyako; Maeda, Miho; Okamura, Jun; Kazama, Takuro; Terao, Yoko; Ohyama, Wataru; Yuza, Yuki; Kaneko, Takashi; Manabe, Atsushi; Kobayashi, Kyoko; Kamibeppu, Kiyoko; Matsushima, Eisuke

    2011-04-10

    The PedsQL 3.0 Cancer Module is a widely used instrument to measure pediatric cancer specific health-related quality of life (HRQOL) for children aged 2 to 18 years. We developed the Japanese version of the PedsQL Cancer Module and investigated its reliability and validity among Japanese children and their parents. Participants were 212 children with cancer and 253 of their parents. Reliability was determined by internal consistency using Cronbach's coefficient alpha and test-retest reliability using intra-class correlation coefficient (ICC). Validity was assessed through factor validity, convergent and discriminant validity, concurrent validity, and clinical validity. Factor validity was examined by exploratory factor analysis. Convergent and discriminant validity were examined by multitrait scaling analysis. Concurrent validity was assessed using Spearman's correlation coefficients between the Cancer Module and Generic Core Scales, and the comparison of the scores of child self-reports with those of other self-rating depression scales for children. Clinical validity was assessed by comparing the on- and off- treatment scores using Kruskal-Wallis and Mann-Whitney U tests. Cronbach's coefficient alpha was over 0.70 for the total scale and over 0.60 for each subscale by age except for the 'pain and hurt' subscale for children aged 5 to 7 years. For test-retest reliability, the ICC exceeded 0.70 for the total scale for each age. Exploratory factor analysis demonstrated sufficient factorial validity. Multitrait scaling analysis showed high success rates. Strong correlations were found between the reports by children and their parents, and the scores of the Cancer Module and the Generic Core Scales except for 'treatment anxiety' subscales for child reports. The Depression Self-Rating Scale for Children (DSRS-C) scores were significantly correlated with emotional domains and the total score of the cancer module. Children who had been off treatment over 12 months demonstrated significantly higher scores than those on treatment. The results demonstrate the reliability and validity of the Japanese version of the PedsQL Cancer Module among Japanese children.

  1. Violent crime rates as a proxy for the social determinants of sexually transmissible infection rates: the consistent state-level correlation between violent crime and reported sexually transmissible infections in the United States, 1981-2010.

    PubMed

    Chesson, Harrell W; Owusu-Edusei, Kwame; Leichliter, Jami S; Aral, Sevgi O

    2013-11-01

    Numerous social determinants of health are associated with violent crime rates and sexually transmissible infection (STI) rates. This report aims to illustrate the potential usefulness of violent crime rates as a proxy for the social determinants of STI rates. For each year from 1981 to 2010, we assessed the strength of the association between the violent crime rate and the gonorrhoea (Neisseria gonorrhoeae) rate (number of total reported cases per 100?000) at the state level. Specifically, for each year, we calculated Pearson correlation coefficients (and P-values) between two variables (the violent crime rate and the natural log of the gonorrhoea rate) for all 50 states and Washington, DC. For comparison, we also examined the correlation between gonorrhoea rates, and rates of poverty and unemployment. We repeated the analysis using overall syphilis rates instead of overall gonorrhoea rates. The correlation between gonorrhoea and violent crime was significant at the P<0.001 level for every year from 1981 to 2010. Syphilis rates were also consistently correlated with violent crime rates. In contrast, the P-value for the correlation coefficient exceeded 0.05 in 9 of the 30 years for the association between gonorrhoea and poverty, and in 17 of the 30 years for that between gonorrhoea and unemployment. Because violent crime is associated with many social determinants of STIs and because it is consistently associated with STI rates, violent crime rates can be a useful proxy for the social determinants of health in statistical analyses of STI rates.

  2. Visualizing Similarity of Appearance by Arrangement of Cards

    PubMed Central

    Nakatsuji, Nao; Ihara, Hisayasu; Seno, Takeharu; Ito, Hiroshi

    2016-01-01

    This study proposes a novel method to extract the configuration of the psychological space by directly measuring subjects' similarity rating without computational work. Although multidimensional scaling (MDS) is well-known as a conventional method for extracting the psychological space, the method requires many pairwise evaluations. The times taken for evaluations increase in proportion to the square of the number of objects in MDS. The proposed method asks subjects to arrange cards on a poster sheet according to the degree of similarity of the objects. To compare the performance of the proposed method with the conventional one, we developed similarity maps of typefaces through the proposed method and through non-metric MDS. We calculated the trace correlation coefficient among all combinations of the configuration for both methods to evaluate the degree of similarity in the obtained configurations. The threshold value of trace correlation coefficient for statistically discriminating similar configuration was decided based on random data. The ratio of the trace correlation coefficient exceeding the threshold value was 62.0% so that the configurations of the typefaces obtained by the proposed method closely resembled those obtained by non-metric MDS. The required duration for the proposed method was approximately one third of the non-metric MDS's duration. In addition, all distances between objects in all the data for both methods were calculated. The frequency for the short distance in the proposed method was lower than that of the non-metric MDS so that a relatively small difference was likely to be emphasized among objects in the configuration by the proposed method. The card arrangement method we here propose, thus serves as a easier and time-saving tool to obtain psychological structures in the fields related to similarity of appearance. PMID:27242611

  3. Abnormal environmental light exposure in the intensive care environment.

    PubMed

    Fan, Emily P; Abbott, Sabra M; Reid, Kathryn J; Zee, Phyllis C; Maas, Matthew B

    2017-08-01

    We sought to characterize ambient light exposure in the intensive care unit (ICU) environment to identify patterns of light exposure relevant to circadian regulation. A light monitor was affixed to subjects' bed at eye level in a modern intensive care unit and continuously recorded illuminescence for at least 24h per subject. Blood was sampled hourly and measured for plasma melatonin. Subjects underwent hourly vital sign and bedside neurologic assessments. Care protocols and the ICU environment were not modified for the study. A total of 67,324 30-second epochs of light data were collected from 17 subjects. Light intensity peaked in the late morning, median 64.1 (interquartile range 19.7-138.7) lux. The 75th percentile of light intensity exceeded 100lx only between 9AM and noon, and never exceeded 150lx. There was no correlation between melatonin amplitude and daytime, nighttime or total light exposure (Spearman's correlation coefficients all <0.2 and p>0.5). Patients' environmental light exposure in the intensive care unit is consistently low and follows a diurnal pattern. No effect of nighttime light exposure was observed on melatonin secretion. Inadequate daytime light exposure in the ICU may contribute to abnormal circadian rhythms. Copyright © 2017 Elsevier Inc. All rights reserved.

  4. Characterization of nonGaussian atmospheric turbulence for prediction of aircraft response statistics

    NASA Technical Reports Server (NTRS)

    Mark, W. D.

    1977-01-01

    Mathematical expressions were derived for the exceedance rates and probability density functions of aircraft response variables using a turbulence model that consists of a low frequency component plus a variance modulated Gaussian turbulence component. The functional form of experimentally observed concave exceedance curves was predicted theoretically, the strength of the concave contribution being governed by the coefficient of variation of the time fluctuating variance of the turbulence. Differences in the functional forms of response exceedance curves and probability densities also were shown to depend primarily on this same coefficient of variation. Criteria were established for the validity of the local stationary assumption that is required in the derivations of the exceedance curves and probability density functions. These criteria are shown to depend on the relative time scale of the fluctuations in the variance, the fluctuations in the turbulence itself, and on the nominal duration of the relevant aircraft impulse response function. Metrics that can be generated from turbulence recordings for testing the validity of the local stationary assumption were developed.

  5. Polygenic variation maintained by balancing selection: pleiotropy, sex-dependent allelic effects and G x E interactions.

    PubMed Central

    Turelli, Michael; Barton, N H

    2004-01-01

    We investigate three alternative selection-based scenarios proposed to maintain polygenic variation: pleiotropic balancing selection, G x E interactions (with spatial or temporal variation in allelic effects), and sex-dependent allelic effects. Each analysis assumes an additive polygenic trait with n diallelic loci under stabilizing selection. We allow loci to have different effects and consider equilibria at which the population mean departs from the stabilizing-selection optimum. Under weak selection, each model produces essentially identical, approximate allele-frequency dynamics. Variation is maintained under pleiotropic balancing selection only at loci for which the strength of balancing selection exceeds the effective strength of stabilizing selection. In addition, for all models, polymorphism requires that the population mean be close enough to the optimum that directional selection does not overwhelm balancing selection. This balance allows many simultaneously stable equilibria, and we explore their properties numerically. Both spatial and temporal G x E can maintain variation at loci for which the coefficient of variation (across environments) of the effect of a substitution exceeds a critical value greater than one. The critical value depends on the correlation between substitution effects at different loci. For large positive correlations (e.g., rho(ij)2>3/4), even extreme fluctuations in allelic effects cannot maintain variation. Surprisingly, this constraint on correlations implies that sex-dependent allelic effects cannot maintain polygenic variation. We present numerical results that support our analytical approximations and discuss our results in connection to relevant data and alternative variance-maintaining mechanisms. PMID:15020487

  6. The relation of ground-water quality to housing density, Cape Cod, Massachusetts

    USGS Publications Warehouse

    Persky, J.H.

    1986-01-01

    Correlation of median nitrate concentration in groundwater with housing density for 18 sample areas on Cape Cod yields a Pearson correlation coefficient of 0.802, which is significant at the 95 % confidence level. In five of nine sample areas where housing density is greater than one unit/acre, nitrate concentrations exceed 5 mg of nitrate/L (the Barnstable County planning goal for nitrate) in 25% of wells. Nitrate concentrations exceed 5 mg of nitrogen/L in 25% of wells in only one of nine sample areas where housing density is less than one unit/acre. Median concentrations of sodium and iron, and median levels of pH and specific conductance, are not significantly correlated with housing density. A computer generated map of nitrate shows a positive relation between nitrate concentration and housing density on Cape Cod. However, the presence of septage- or sewage-disposal sites and fertilizer use are also important factors that affect the nitrate concentration. A map of specific conductance also shows a positive relation to housing density, but little or no relation between housing density and sodium, ammonia, pH, or iron is apparent on the maps. Chemical analyses of samples collected from 3,468 private- and public-supply wells between January 1980 and June 1984 were used to examine the extent to which housing density determines water quality on Cape Cod, an area largely unsewered and underlain by a sole source aquifer. (Author 's abstract)

  7. Validation of an analytical method for the quantitative determination of selenium in bacterial biomass by ultraviolet-visible spectrophotometry.

    PubMed

    Mörschbächer, Ana Paula; Dullius, Anja; Dullius, Carlos Henrique; Bandt, Cassiano Ricardo; Kuhn, Daniel; Brietzke, Débora Tairini; Malmann Kuffel, Fernando José; Etgeton, Henrique Pretto; Altmayer, Taciélen; Gonçalves, Tamara Engelmann; Oreste, Eliézer Quadro; Ribeiro, Anderson Schwingel; de Souza, Claucia Fernanda Volken; Hoehne, Lucélia

    2018-07-30

    The present paper describes the validation of a spectrophotometry method involving molecular absorption in the visible ultraviolet-visible (UV-Vis) region for selenium (Se) determination in the bacterial biomass produced by lactic acid bacteria (LAB). The method was found to be suitable for the target application and presented a linearity range from 0.025 to 0.250 mg/L Se. The angular and linear coefficients of the linear equation were 1.0678 and 0.0197 mg/L Se, respectively, and the linear correlation coefficient (R 2 ) was 0.9991. Analyte recovery exceeded 96% with a relative standard deviation (RSD) below 3%. The Se contents in LAB ranged from 0.01 to 20 mg/g. The Se contents in the bacterial biomass determined by UV-Vis were not significantly different (p > 0.05) those determined by graphite furnace atomic absorption spectrometry. Thus, Se can be quantified in LAB biomass using this relatively simpler technique. Copyright © 2018 Elsevier Ltd. All rights reserved.

  8. Degeneracy of gravitational waveforms in the context of GW150914

    NASA Astrophysics Data System (ADS)

    Creswell, James; Liu, Hao; Jackson, Andrew D.; von Hausegger, Sebastian; Naselsky, Pavel

    2018-03-01

    We study the degeneracy of theoretical gravitational waveforms for binary black hole mergers using an aligned-spin effective-one-body model. After appropriate truncation, bandpassing, and matching, we identify regions in the mass–spin parameter space containing waveforms similar to the template proposed for GW150914, with masses m1 = 36+5‑4 Msolar and m2 = 29+4‑4 Msolar, using the cross-correlation coefficient as a measure of the similarity between waveforms. Remarkably high cross-correlations are found across broad regions of parameter space. The associated uncertanties exceed these from LIGO's Bayesian analysis considerably. We have shown that waveforms with greatly increased masses, such as m1 = 70 Msolar and m2 = 35 Msolar, and strong anti-aligned spins (χ1 = 0.95 and χ2 = ‑0.95) yield almost the same signal-to-noise ratio in the strain data for GW150914.

  9. Malaria’s Indirect Contribution to All-Cause Mortality in the Andaman Islands during the Colonial Era

    PubMed Central

    Shanks, G. Dennis; Hay, Simon I.; Bradley, David J.

    2009-01-01

    Malaria appears to have a substantial secondary effect on other causes of mortality. From the 19th century, malaria epidemics in the Andaman Islands Penal Colony were initiated by the brackish swamp breeding malaria vector Anopheles sundaicus and fueled by the importation of new prisoners. Malaria was a major determinant of the highly variable all-cause mortality rate (correlation coefficient r2=0.60, n=68, p< 0.0001) from 1872 to 1939. Directly attributed malaria mortality based on postmortem examinations rarely exceeded one fifth of total mortality. Infectious diseases such as pneumonia, tuberculosis, dysentery and diarrhea, which combined with malaria made up a majority of all-cause mortality, were positively correlated to malaria incidence over several decades. Deaths secondary to malaria (indirect malaria mortality) were at least as great as mortality directly attributed to malaria infections. PMID:18599354

  10. Intelligent control system for continuous technological process of alkylation

    NASA Astrophysics Data System (ADS)

    Gebel, E. S.; Hakimov, R. A.

    2018-01-01

    Relevance of intelligent control for complex dynamic objects and processes are shown in this paper. The model of a virtual analyzer based on a neural network is proposed. Comparative analysis of mathematical models implemented in MathLab software showed that the most effective from the point of view of the reproducibility of the result is the model with seven neurons in the hidden layer, the training of which was performed using the method of scaled coupled gradients. Comparison of the data from the laboratory analysis and the theoretical model are showed that the root-mean-square error does not exceed 3.5, and the calculated value of the correlation coefficient corresponds to a "strong" connection between the values.

  11. Velocity and bottom-stress measurements in the bottom boundary layer, outer Norton Sound, Alaska.

    USGS Publications Warehouse

    Cacchione, D.A.; Drake, D.E.; Wiberg, P.

    1982-01-01

    We have used long-term measurements of near-bottom velocities at four heights above the sea floor in Norton Sound, Alaska, to compute hourly values of shear velocity u., roughness and bottom-drag coefficient. Maximum sediment resuspension and transport, predicted for periods when the computed value of u. exceeds a critical level, occur during peak tidal currents associated with spring tides. The fortnightly variation in u. is correlated with a distinct nepheloid layer that intensifies and thickens during spring tides and diminishes and thins during neap tides. The passage of a storm near the end of the experiment caused significantly higher u. values than those found during fair weather.-from Authros

  12. Novel wideband MIMO antennas that can cover the whole LTE spectrum in handsets and portable computers.

    PubMed

    Sanad, Mohamed; Hassan, Noha

    2014-01-01

    A dual resonant antenna configuration is developed for multistandard multifunction mobile handsets and portable computers. Only two wideband resonant antennas can cover most of the LTE spectrums in portable communication equipment. The bandwidth that can be covered by each antenna exceeds 70% without using any matching or tuning circuits, with efficiencies that reach 80%. Thus, a dual configuration of them is capable of covering up to 39 LTE (4G) bands besides the existing 2G and 3G bands. 2×2 MIMO configurations have been also developed for the two wideband antennas with a maximum isolation and a minimum correlation coefficient between the primary and the diversity antennas.

  13. Simulating floods in the Amazon River Basin: Impacts of new river geomorphic and dynamic flow parameterizations

    NASA Astrophysics Data System (ADS)

    Coe, M. T.; Costa, M. H.; Howard, E. A.

    2006-12-01

    In this paper we analyze the hydrology of the Amazon River system for the latter half of the 20th century with our recently completed model of terrestrial hydrology (Terrestrial Hydrology Model with Biogeochemistry, THMB). We evaluate the simulated hydrology of the Central Amazon basin against limited observations of river discharge, floodplain inundation, and water height and analyze the spatial and temporal variability of the hydrology for the period 1939-1998. We compare the simulated discharge and floodplain inundated area to the simulations by Coe et al., 2002 using a previous version of this model. The new model simulates the discharge and flooded area in better agreement with the observations than the previous model. The coefficient of correlation between the simulated and observed discharge for the greater than 27000 monthly observations of discharge at 120 sites throughout the Brazilian Amazon is 0.9874 compared to 0.9744 for the previous model. The coefficient of correlation between the simulated monthly flooded area and the satellite-based estimates by Sippel et al., 1998 exceeds 0.7 for 8 of the 12 mainstem reaches. The seasonal and inter-annual variability of the water height and the river slope compares favorably to the satellite altimetric measurements of height reported by Birkett et al., 2002.

  14. Continuous-energy eigenvalue sensitivity coefficient calculations in TSUNAMI-3D

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Perfetti, C. M.; Rearden, B. T.

    2013-07-01

    Two methods for calculating eigenvalue sensitivity coefficients in continuous-energy Monte Carlo applications were implemented in the KENO code within the SCALE code package. The methods were used to calculate sensitivity coefficients for several test problems and produced sensitivity coefficients that agreed well with both reference sensitivities and multigroup TSUNAMI-3D sensitivity coefficients. The newly developed CLUTCH method was observed to produce sensitivity coefficients with high figures of merit and a low memory footprint, and both continuous-energy sensitivity methods met or exceeded the accuracy of the multigroup TSUNAMI-3D calculations. (authors)

  15. Development of a SCALE Tool for Continuous-Energy Eigenvalue Sensitivity Coefficient Calculations

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Perfetti, Christopher M; Rearden, Bradley T

    2013-01-01

    Two methods for calculating eigenvalue sensitivity coefficients in continuous-energy Monte Carlo applications were implemented in the KENO code within the SCALE code package. The methods were used to calculate sensitivity coefficients for several criticality safety problems and produced sensitivity coefficients that agreed well with both reference sensitivities and multigroup TSUNAMI-3D sensitivity coefficients. The newly developed CLUTCH method was observed to produce sensitivity coefficients with high figures of merit and low memory requirements, and both continuous-energy sensitivity methods met or exceeded the accuracy of the multigroup TSUNAMI-3D calculations.

  16. Transfer coefficients in ultracold strongly coupled plasma

    NASA Astrophysics Data System (ADS)

    Bobrov, A. A.; Vorob'ev, V. S.; Zelener, B. V.

    2018-03-01

    We use both analytical and molecular dynamic methods for electron transfer coefficients in an ultracold plasma when its temperature is small and the coupling parameter characterizing the interaction of electrons and ions exceeds unity. For these conditions, we use the approach of nearest neighbor to determine the average electron (ion) diffusion coefficient and to calculate other electron transfer coefficients (viscosity and electrical and thermal conductivities). Molecular dynamics simulations produce electronic and ionic diffusion coefficients, confirming the reliability of these results. The results compare favorably with experimental and numerical data from earlier studies.

  17. A new correlation coefficient for bivariate time-series data

    NASA Astrophysics Data System (ADS)

    Erdem, Orhan; Ceyhan, Elvan; Varli, Yusuf

    2014-11-01

    The correlation in time series has received considerable attention in the literature. Its use has attained an important role in the social sciences and finance. For example, pair trading in finance is concerned with the correlation between stock prices, returns, etc. In general, Pearson’s correlation coefficient is employed in these areas although it has many underlying assumptions which restrict its use. Here, we introduce a new correlation coefficient which takes into account the lag difference of data points. We investigate the properties of this new correlation coefficient. We demonstrate that it is more appropriate for showing the direction of the covariation of the two variables over time. We also compare the performance of the new correlation coefficient with Pearson’s correlation coefficient and Detrended Cross-Correlation Analysis (DCCA) via simulated examples.

  18. Venipuncture versus peripheral catheter: do infusions alter laboratory results?

    PubMed

    Hambleton, Victoria Lerma; Gómez, Ignacio Arribas; Andreu, Francisco A Bernabeu

    2014-01-01

    Our aim was to evaluate the equivalence between analytic parameters from blood samples obtained from a saline solution lock device used for the infusion of drugs and those from venipuncture. In our emergency department, patients bearing a saline solution lock device have blood extracted by venipuncture to avoid possible contamination of the sample. Adults from the emergency department with a saline solution lock device who required laboratory tests were selected as candidates for this cross-sectional observational study. Infusions were halted and flushed with 0.9% saline solution; 2 minutes later, 2 mL of blood was drawn and discarded, and the corresponding laboratory tubes were filled. Immediately after, another sample was withdrawn from the opposite extremity by venipuncture. Both samples were analyzed for hematology, biochemistry, venous blood gases, and coagulation parameters. Concordance was evaluated by use of the intraclass correlation coefficient with its 95% confidence intervals; Bland-Altman plots were used to illustrate the percentage of samples with differences exceeding 2 SDs. The mean differences were also checked to detect those exceeding the laboratory's systematic error. An intraclass correlation coefficient of over 0.9 was achieved for all parameters except for pH, partial pressure of carbon dioxide, and partial pressure of oxygen. Differences of over 2 SDs were found in fewer than 10% of all parameters. None of them exceeded 3 SDs, except for pH and venous blood gases. All parameters showed differences below the laboratory's accepted systematic error except for pH and venous blood gases. Blood samples extracted from a peripheral catheter with or without drug infusions are valid for the analysis of hematology, biochemistry, and coagulation parameters but not for venous blood gases. Nurses should know the benefits of using an existing peripheral catheter for drawing blood samples for laboratory analysis even when infusing commonly used drugs. Emergency nurses should consider collecting blood specimens from a venous access device regardless of the type of drug infusions administered, because it is a safe, simple, and fast technique, which is time efficient when treating patients with limited venous access sites. This procedure reduces patient discomfort and the risk of complications related to venipunctures. Copyright © 2014 Emergency Nurses Association. Published by Mosby, Inc. All rights reserved.

  19. Occurrence and carcinogenic potential of airborne polycyclic aromatic hydrocarbons in some large-scale enclosed/semi-enclosed vehicle parking areas.

    PubMed

    Li, Huiru; Zeng, Xiangying; Zhang, Delin; Chen, Pei; Yu, Zhiqiang; Sheng, Guoying; Fu, Jiamo; Peng, Ping'an

    2014-06-15

    Polycyclic aromatic hydrocarbons (PAHs) originating from vehicle exhaust have aroused much attention due to their potential healthy effect. In this study, air samples were collected from three representative parking lots in a metropolitan area, analyzed for PAHs and evaluated for inhalation risk. Atmospheric PAH levels of these parking areas ranged between 1,178-4,793 ng m(-3), one order of magnitude higher than general urban areas. Their benzo[a]pyrene equivalent (BaPeq) values varied in 11.0-98.0 ng m(-3), far exceeding the air quality standard of WHO (1.0 ng m(-3)). Monte Carlo simulation (100,000 trials) results suggest that the potential lifetime inhalation cancer risks of PAHs were 0.27 × 10(-5) to 7.11 × 10(-5) for park employees, which are in the acceptable range acknowledged by US EPA (1.0 × 10(-6) to 1.0 × 10(-4)). Several source diagnostic methods proved that vehicle exhaust was the dominant PAH contributor of these parks with the contribution percentages being >53%; oil combustion and/or coal combustion were other important sources. Logarithms of gas-particle distribution coefficients (Kps) of PAHs in all studied parks were linearly correlated with those of both their sub-cooled vapor pressures (pLs) and octanol-air partition coefficients (KOAs). The correlation coefficients indicated that both adsorption onto black carbon and absorption into organic matter were involved in the partition process, but the latter was dominant. Copyright © 2014 Elsevier B.V. All rights reserved.

  20. Genome-scale cluster analysis of replicated microarrays using shrinkage correlation coefficient.

    PubMed

    Yao, Jianchao; Chang, Chunqi; Salmi, Mari L; Hung, Yeung Sam; Loraine, Ann; Roux, Stanley J

    2008-06-18

    Currently, clustering with some form of correlation coefficient as the gene similarity metric has become a popular method for profiling genomic data. The Pearson correlation coefficient and the standard deviation (SD)-weighted correlation coefficient are the two most widely-used correlations as the similarity metrics in clustering microarray data. However, these two correlations are not optimal for analyzing replicated microarray data generated by most laboratories. An effective correlation coefficient is needed to provide statistically sufficient analysis of replicated microarray data. In this study, we describe a novel correlation coefficient, shrinkage correlation coefficient (SCC), that fully exploits the similarity between the replicated microarray experimental samples. The methodology considers both the number of replicates and the variance within each experimental group in clustering expression data, and provides a robust statistical estimation of the error of replicated microarray data. The value of SCC is revealed by its comparison with two other correlation coefficients that are currently the most widely-used (Pearson correlation coefficient and SD-weighted correlation coefficient) using statistical measures on both synthetic expression data as well as real gene expression data from Saccharomyces cerevisiae. Two leading clustering methods, hierarchical and k-means clustering were applied for the comparison. The comparison indicated that using SCC achieves better clustering performance. Applying SCC-based hierarchical clustering to the replicated microarray data obtained from germinating spores of the fern Ceratopteris richardii, we discovered two clusters of genes with shared expression patterns during spore germination. Functional analysis suggested that some of the genetic mechanisms that control germination in such diverse plant lineages as mosses and angiosperms are also conserved among ferns. This study shows that SCC is an alternative to the Pearson correlation coefficient and the SD-weighted correlation coefficient, and is particularly useful for clustering replicated microarray data. This computational approach should be generally useful for proteomic data or other high-throughput analysis methodology.

  1. Tests of Hypotheses Arising In the Correlated Random Coefficient Model*

    PubMed Central

    Heckman, James J.; Schmierer, Daniel

    2010-01-01

    This paper examines the correlated random coefficient model. It extends the analysis of Swamy (1971), who pioneered the uncorrelated random coefficient model in economics. We develop the properties of the correlated random coefficient model and derive a new representation of the variance of the instrumental variable estimator for that model. We develop tests of the validity of the correlated random coefficient model against the null hypothesis of the uncorrelated random coefficient model. PMID:21170148

  2. OC19 - Measuring feasibility, reliability and validity of the Greek version of PedsQL cardiac module.

    PubMed

    Drakouli, Maria; Petsios, Konstantinos; Matziou, Vasiliki

    2016-05-09

    Theme: Cardiology Introduction: Measuring quality of life (QoL) in children and adolescents with congenital heart disease (CHD) is of great clinical importance. The aim of the study was: (a) to adapt the PedsQL Cardiac Module for children aged two to 18 years with CHD in a sample of the Greek population; (b) to determine its reliability and validity. Forward and backward translation methodology was used. Parents and children completed the instrument during: (a) hospitalization and (b) visits in the paediatric cardiology outpatient department. Cross-informant variance between children and parents was thoroughly assessed. Missing item responses did not exceed 5%. All internal consistency reliability coefficients for the inventory exceeded the minimum standards for group comparisons, over 0.75. Hypothesized correlations between cardiac module and core scales were statistically significant, (p<0.05). Agreement between children and parents was relatively high. Pilot study results will be additionally presented. The findings support the feasibility, reliability and validity of the Greek translation of the PedsQL Cardiac Module in children with congenital heart defect (CHD).

  3. Deviations from LTE in a stellar atmosphere

    NASA Technical Reports Server (NTRS)

    Kalkofen, W.; Klein, R. I.; Stein, R. F.

    1979-01-01

    Deviations for LTE are investigated in an atmosphere of hydrogen atoms with one bound level, satisfying the equations of radiative, hydrostatic, and statistical equilibrium. The departure coefficient and the kinetic temperature as functions of the frequency dependence of the radiative cross section are studied analytically and numerically. Near the outer boundary of the atmosphere, the departure coefficient is smaller than unity when the radiative cross section grows with frequency faster than with the square of frequency; it exceeds unity otherwise. Far from the boundary the departure coefficient tends to exceed unity for any frequency dependence of the radiative cross section. Overpopulation always implies that the kinetic temperature in the statistical-equilibrium atmosphere is higher than the temperature in the corresponding LTE atmosphere. Upper and lower bounds on the kinetic temperature are given for an atmosphere with deviations from LTE only in the optically shallow layers when the emergent intensity can be described by a radiation temperature.

  4. LASER APPLICATIONS AND OTHER TOPICS IN QUANTUM ELECTRONICS: Measurement of optical absorption in polycrystalline CVD diamond plates by the phase photothermal method at a wavelength of 10.6 μm

    NASA Astrophysics Data System (ADS)

    Luk'yanov, A. Yu; Ral'chenko, Viktor G.; Khomich, A. V.; Serdtsev, E. V.; Volkov, P. V.; Savel'ev, A. V.; Konov, Vitalii I.

    2008-12-01

    A highly-efficient phase photothermal method is developed for quantitative measurements of the small optical absorption coefficient in thin plates made of highly transparent materials in which bulk losses significantly exceed surface losses. The bulk absorption coefficient at 10.6 μm is estimated in polycrystalline diamond plates grown from the vapour phase (a CVD diamond). The results are compared with those for natural and synthetic diamond single crystals and with the concentrations of nitrogen and hydrogen impurities. The absorption coefficient of the best samples of the CVD diamond did not exceed 0.06 cm-1, which, taking into account the high thermal conductivity of the CVD diamond (1800-2200 W mK-1 at room temperature), makes this material attractive for fabricating output windows of high-power CO2 lasers, especially for manufacturing large-size optics.

  5. The Chinese version of the Pediatric Quality of Life Inventory™ (PedsQL™) 3.0 Asthma Module: reliability and validity.

    PubMed

    Feng, Lifen; Zhang, Yingfen; Chen, Ruoqing; Hao, Yuantao

    2011-08-07

    Health-related quality of life (HRQOL) has been recognized as an important health outcome measurement for pediatric patients. One of the most promising instruments in measuring pediatric HRQOL emerged in recent years is the Pediatric Quality of Life Inventory (PedsQL™). The PedsQL™ 3.0 Asthma Module, one of the PedsQL™disease-specific scales, was designed to measure HRQOL dimensions specifically tailored for pediatric asthma. The present study is aimed to evaluate the psychometric properties of the Chinese version of the PedsQL™ 3.0 Asthma Module. The PedsQL™ 3.0 Asthma Module was translated into Chinese following the PedsQL™ Measurement Model Translation Methodology. The Chinese version scale was administered to 204 children with asthma and 337 parents of children with asthma from four Triple A hospitals. The psychometric properties were then evaluated. The percentage of missing value for each item of the scale ranged from 0.00% to 8.31%. All child self-report subscales and parent proxy-report subscales approached or exceeded the minimum reliability standard of 0.70 for alpha coefficient, except 3 subscales of Young Child (aged 5-7) self-report (alphas ranging from 0.59 to 0.68). Test-retest reliability was satisfactory with intraclass correlation coefficients (ICCs) which exceeded the recommended standard of 0.80 in all subscales. Correlation coefficients between items and their hypothesized subscales were higher than those with other subscales. The PedsQL™ 3.0 Asthma Module distinguished between outpatients and inpatients. Patients with mild asthma reported higher scores than those with moderate/severe asthma in majority of subscales. The intercorrelations among the PedsQL™ 3.0 Asthma Module subscales and the PedsQL™ 4.0 Generic Core Scales were in medium to large effect size. The child self-report scores were consistent with the parent proxy-report scores. The Chinese version of the PedsQL™ 3.0 Asthma Module has acceptable psychometric properties, except the internal consistency reliability for Young Child (aged 5-7) self-report. Further studies should be focused on testing responsiveness of the Chinese version scale in longitudinal studies, evaluating the reliability and validity of the scale for the patients with severe asthma or teens independently, and assessing HRQOL of children with asthma in other areas.

  6. Modified Regression Correlation Coefficient for Poisson Regression Model

    NASA Astrophysics Data System (ADS)

    Kaengthong, Nattacha; Domthong, Uthumporn

    2017-09-01

    This study gives attention to indicators in predictive power of the Generalized Linear Model (GLM) which are widely used; however, often having some restrictions. We are interested in regression correlation coefficient for a Poisson regression model. This is a measure of predictive power, and defined by the relationship between the dependent variable (Y) and the expected value of the dependent variable given the independent variables [E(Y|X)] for the Poisson regression model. The dependent variable is distributed as Poisson. The purpose of this research was modifying regression correlation coefficient for Poisson regression model. We also compare the proposed modified regression correlation coefficient with the traditional regression correlation coefficient in the case of two or more independent variables, and having multicollinearity in independent variables. The result shows that the proposed regression correlation coefficient is better than the traditional regression correlation coefficient based on Bias and the Root Mean Square Error (RMSE).

  7. Distance correlation methods for discovering associations in large astrophysical databases

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Martínez-Gómez, Elizabeth; Richards, Mercedes T.; Richards, Donald St. P., E-mail: elizabeth.martinez@itam.mx, E-mail: mrichards@astro.psu.edu, E-mail: richards@stat.psu.edu

    2014-01-20

    High-dimensional, large-sample astrophysical databases of galaxy clusters, such as the Chandra Deep Field South COMBO-17 database, provide measurements on many variables for thousands of galaxies and a range of redshifts. Current understanding of galaxy formation and evolution rests sensitively on relationships between different astrophysical variables; hence an ability to detect and verify associations or correlations between variables is important in astrophysical research. In this paper, we apply a recently defined statistical measure called the distance correlation coefficient, which can be used to identify new associations and correlations between astrophysical variables. The distance correlation coefficient applies to variables of any dimension,more » can be used to determine smaller sets of variables that provide equivalent astrophysical information, is zero only when variables are independent, and is capable of detecting nonlinear associations that are undetectable by the classical Pearson correlation coefficient. Hence, the distance correlation coefficient provides more information than the Pearson coefficient. We analyze numerous pairs of variables in the COMBO-17 database with the distance correlation method and with the maximal information coefficient. We show that the Pearson coefficient can be estimated with higher accuracy from the corresponding distance correlation coefficient than from the maximal information coefficient. For given values of the Pearson coefficient, the distance correlation method has a greater ability than the maximal information coefficient to resolve astrophysical data into highly concentrated horseshoe- or V-shapes, which enhances classification and pattern identification. These results are observed over a range of redshifts beyond the local universe and for galaxies from elliptical to spiral.« less

  8. Clustering Coefficients for Correlation Networks.

    PubMed

    Masuda, Naoki; Sakaki, Michiko; Ezaki, Takahiro; Watanabe, Takamitsu

    2018-01-01

    Graph theory is a useful tool for deciphering structural and functional networks of the brain on various spatial and temporal scales. The clustering coefficient quantifies the abundance of connected triangles in a network and is a major descriptive statistics of networks. For example, it finds an application in the assessment of small-worldness of brain networks, which is affected by attentional and cognitive conditions, age, psychiatric disorders and so forth. However, it remains unclear how the clustering coefficient should be measured in a correlation-based network, which is among major representations of brain networks. In the present article, we propose clustering coefficients tailored to correlation matrices. The key idea is to use three-way partial correlation or partial mutual information to measure the strength of the association between the two neighboring nodes of a focal node relative to the amount of pseudo-correlation expected from indirect paths between the nodes. Our method avoids the difficulties of previous applications of clustering coefficient (and other) measures in defining correlational networks, i.e., thresholding on the correlation value, discarding of negative correlation values, the pseudo-correlation problem and full partial correlation matrices whose estimation is computationally difficult. For proof of concept, we apply the proposed clustering coefficient measures to functional magnetic resonance imaging data obtained from healthy participants of various ages and compare them with conventional clustering coefficients. We show that the clustering coefficients decline with the age. The proposed clustering coefficients are more strongly correlated with age than the conventional ones are. We also show that the local variants of the proposed clustering coefficients (i.e., abundance of triangles around a focal node) are useful in characterizing individual nodes. In contrast, the conventional local clustering coefficients were strongly correlated with and therefore may be confounded by the node's connectivity. The proposed methods are expected to help us to understand clustering and lack thereof in correlational brain networks, such as those derived from functional time series and across-participant correlation in neuroanatomical properties.

  9. Clustering Coefficients for Correlation Networks

    PubMed Central

    Masuda, Naoki; Sakaki, Michiko; Ezaki, Takahiro; Watanabe, Takamitsu

    2018-01-01

    Graph theory is a useful tool for deciphering structural and functional networks of the brain on various spatial and temporal scales. The clustering coefficient quantifies the abundance of connected triangles in a network and is a major descriptive statistics of networks. For example, it finds an application in the assessment of small-worldness of brain networks, which is affected by attentional and cognitive conditions, age, psychiatric disorders and so forth. However, it remains unclear how the clustering coefficient should be measured in a correlation-based network, which is among major representations of brain networks. In the present article, we propose clustering coefficients tailored to correlation matrices. The key idea is to use three-way partial correlation or partial mutual information to measure the strength of the association between the two neighboring nodes of a focal node relative to the amount of pseudo-correlation expected from indirect paths between the nodes. Our method avoids the difficulties of previous applications of clustering coefficient (and other) measures in defining correlational networks, i.e., thresholding on the correlation value, discarding of negative correlation values, the pseudo-correlation problem and full partial correlation matrices whose estimation is computationally difficult. For proof of concept, we apply the proposed clustering coefficient measures to functional magnetic resonance imaging data obtained from healthy participants of various ages and compare them with conventional clustering coefficients. We show that the clustering coefficients decline with the age. The proposed clustering coefficients are more strongly correlated with age than the conventional ones are. We also show that the local variants of the proposed clustering coefficients (i.e., abundance of triangles around a focal node) are useful in characterizing individual nodes. In contrast, the conventional local clustering coefficients were strongly correlated with and therefore may be confounded by the node's connectivity. The proposed methods are expected to help us to understand clustering and lack thereof in correlational brain networks, such as those derived from functional time series and across-participant correlation in neuroanatomical properties. PMID:29599714

  10. [Correlation coefficient-based classification method of hydrological dependence variability: With auto-regression model as example].

    PubMed

    Zhao, Yu Xi; Xie, Ping; Sang, Yan Fang; Wu, Zi Yi

    2018-04-01

    Hydrological process evaluation is temporal dependent. Hydrological time series including dependence components do not meet the data consistency assumption for hydrological computation. Both of those factors cause great difficulty for water researches. Given the existence of hydrological dependence variability, we proposed a correlationcoefficient-based method for significance evaluation of hydrological dependence based on auto-regression model. By calculating the correlation coefficient between the original series and its dependence component and selecting reasonable thresholds of correlation coefficient, this method divided significance degree of dependence into no variability, weak variability, mid variability, strong variability, and drastic variability. By deducing the relationship between correlation coefficient and auto-correlation coefficient in each order of series, we found that the correlation coefficient was mainly determined by the magnitude of auto-correlation coefficient from the 1 order to p order, which clarified the theoretical basis of this method. With the first-order and second-order auto-regression models as examples, the reasonability of the deduced formula was verified through Monte-Carlo experiments to classify the relationship between correlation coefficient and auto-correlation coefficient. This method was used to analyze three observed hydrological time series. The results indicated the coexistence of stochastic and dependence characteristics in hydrological process.

  11. 40 CFR Appendix F to Part 60 - Quality Assurance Procedures

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... plus the 2.5 percent error confidence coefficient of a series of tests divided by the mean of the RM... the daily zero (or low-level) CD or the daily high-level CD exceeds two times the limits of the... (or low-level) or high-level CD result exceeds four times the applicable drift specification in...

  12. 40 CFR Appendix F to Part 60 - Quality Assurance Procedures

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... plus the 2.5 percent error confidence coefficient of a series of tests divided by the mean of the RM...-level) CD or the daily high-level CD exceeds two times the limits of the applicable PS's in appendix B... result exceeds four times the applicable drift specification in appendix B during any CD check, the CEMS...

  13. 40 CFR Appendix F to Part 60 - Quality Assurance Procedures

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... plus the 2.5 percent error confidence coefficient of a series of tests divided by the mean of the RM...-level) CD or the daily high-level CD exceeds two times the limits of the applicable PS's in appendix B... result exceeds four times the applicable drift specification in appendix B during any CD check, the CEMS...

  14. 40 CFR Appendix F to Part 60 - Quality Assurance Procedures

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... plus the 2.5 percent error confidence coefficient of a series of tests divided by the mean of the RM...-level) CD or the daily high-level CD exceeds two times the limits of the applicable PS's in appendix B... result exceeds four times the applicable drift specification in appendix B during any CD check, the CEMS...

  15. Novel Wideband MIMO Antennas That Can Cover the Whole LTE Spectrum in Handsets and Portable Computers

    PubMed Central

    Sanad, Mohamed; Hassan, Noha

    2014-01-01

    A dual resonant antenna configuration is developed for multistandard multifunction mobile handsets and portable computers. Only two wideband resonant antennas can cover most of the LTE spectrums in portable communication equipment. The bandwidth that can be covered by each antenna exceeds 70% without using any matching or tuning circuits, with efficiencies that reach 80%. Thus, a dual configuration of them is capable of covering up to 39 LTE (4G) bands besides the existing 2G and 3G bands. 2 × 2 MIMO configurations have been also developed for the two wideband antennas with a maximum isolation and a minimum correlation coefficient between the primary and the diversity antennas. PMID:24558322

  16. Estimation of the biserial correlation and its sampling variance for use in meta-analysis.

    PubMed

    Jacobs, Perke; Viechtbauer, Wolfgang

    2017-06-01

    Meta-analyses are often used to synthesize the findings of studies examining the correlational relationship between two continuous variables. When only dichotomous measurements are available for one of the two variables, the biserial correlation coefficient can be used to estimate the product-moment correlation between the two underlying continuous variables. Unlike the point-biserial correlation coefficient, biserial correlation coefficients can therefore be integrated with product-moment correlation coefficients in the same meta-analysis. The present article describes the estimation of the biserial correlation coefficient for meta-analytic purposes and reports simulation results comparing different methods for estimating the coefficient's sampling variance. The findings indicate that commonly employed methods yield inconsistent estimates of the sampling variance across a broad range of research situations. In contrast, consistent estimates can be obtained using two methods that appear to be unknown in the meta-analytic literature. A variance-stabilizing transformation for the biserial correlation coefficient is described that allows for the construction of confidence intervals for individual coefficients with close to nominal coverage probabilities in most of the examined conditions. Copyright © 2016 John Wiley & Sons, Ltd. Copyright © 2016 John Wiley & Sons, Ltd.

  17. Laboratory test investigations on soil water characteristic curve and air permeability of municipal solid waste.

    PubMed

    Shi, Jianyong; Wu, Xun; Ai, Yingbo; Zhang, Zhen

    2018-05-01

    The air permeability coefficient has a high correlation with the water content of municipal solid waste. In this study, continuous drying methodology using a tension meter was employed to construct the soil water characteristic curve of municipal solid waste (M-SWCC). The municipal solid waste air permeability test was conducted by a newly designed apparatus. The measured M-SWCC was well reproduced by the van Genuchten (V-G) model and was used to predict the parameters of typical points in M-SWCC, including saturated water content, field capacity, residual water content and water content at the inflection point. It was found that the M-SWCC was significantly influenced by void ratio. The final evaporation and test period of M-SWCC increase with the increase in void ratio of municipal solid waste. The evolution of air permeability coefficient with water content of municipal solid waste depicted three distinct characteristic stages. It was observed that the water contents that corresponded to the two cut-off points of the three stages were residual water content and water content at the inflection point, respectively. The air permeability coefficient of municipal solid waste decreased with the increase of the water content from zero to the residual water content. The air permeability coefficient was almost invariable when the water content increased from residual water content to the water content at the inflection point. When the water content of municipal solid waste exceeded the water content at the inflection point, the air permeability coefficient sharply decreased with the increase of water content.

  18. Estimation of the simple correlation coefficient.

    PubMed

    Shieh, Gwowen

    2010-11-01

    This article investigates some unfamiliar properties of the Pearson product-moment correlation coefficient for the estimation of simple correlation coefficient. Although Pearson's r is biased, except for limited situations, and the minimum variance unbiased estimator has been proposed in the literature, researchers routinely employ the sample correlation coefficient in their practical applications, because of its simplicity and popularity. In order to support such practice, this study examines the mean squared errors of r and several prominent formulas. The results reveal specific situations in which the sample correlation coefficient performs better than the unbiased and nearly unbiased estimators, facilitating recommendation of r as an effect size index for the strength of linear association between two variables. In addition, related issues of estimating the squared simple correlation coefficient are also considered.

  19. Impact of angiogenesis-related gene expression on the tracer kinetics of 18F-FDG in colorectal tumors.

    PubMed

    Strauss, Ludwig G; Koczan, Dirk; Klippel, Sven; Pan, Leyun; Cheng, Caixia; Willis, Stefan; Haberkorn, Uwe; Dimitrakopoulou-Strauss, Antonia

    2008-08-01

    18F-FDG kinetics are primarily dependent on the expression of genes associated with glucose transporters and hexokinases but may be modulated by other genes. The dependency of 18F-FDG kinetics on angiogenesis-related gene expression was evaluated in this study. Patients with primary colorectal tumors (n = 25) were examined with PET and 18F-FDG within 2 days before surgery. Tissue specimens were obtained from the tumor and the normal colon during surgery, and gene expression was assessed using gene arrays. Overall, 23 angiogenesis-related genes were identified with a tumor-to-normal ratio exceeding 1.50. Analysis revealed a significant correlation between k1 and vascular endothelial growth factor (VEGF-A, r = 0.51) and between fractal dimension and angiopoietin-2 (r = 0.48). k3 was negatively correlated with VEGF-B (r = -0.46), and a positive correlation was noted for angiopoietin-like 4 gene (r = 0.42). A multiple linear regression analysis was used for the PET parameters to predict the gene expression, and a correlation coefficient of r = 0.75 was obtained for VEGF-A and of r = 0.76 for the angiopoietin-2 expression. Thus, on the basis of these multiple correlation coefficients, angiogenesis-related gene expression contributes to about 50% of the variance of the 18F-FDG kinetic data. The global 18F-FDG uptake, as measured by the standardized uptake value and influx, was not significantly correlated with angiogenesis-associated genes. 18F-FDG kinetics are modulated by angiogenesis-related genes. The transport rate for 18F-FDG (k1) is higher in tumors with a higher expression of VEGF-A and angiopoietin-2. The regression functions for the PET parameters provide the possibility to predict the gene expression of VEGF-A and angiopoietin-2.

  20. The Attenuation of Correlation Coefficients: A Statistical Literacy Issue

    ERIC Educational Resources Information Center

    Trafimow, David

    2016-01-01

    Much of the science reported in the media depends on correlation coefficients. But the size of correlation coefficients depends, in part, on the reliability with which the correlated variables are measured. Understanding this is a statistical literacy issue.

  1. Thermal/structural analyses of several hydrogen-cooled leading-edge concepts for hypersonic flight vehicles

    NASA Technical Reports Server (NTRS)

    Gladden, Herbert J.; Melis, Matthew E.; Mockler, Theodore T.; Tong, Mike

    1990-01-01

    The aerodynamic heating at high flight Mach numbers, when shock interference heating is included, can be extremely high and can exceed the capability of most conventional metallic and potential ceramic materials available. Numerical analyses of the heat transfer and thermal stresses are performed on three actively cooled leading-edge geometries (models) made of three different materials to address the issue of survivability in a hostile environment. These analyses show a mixture of results from one configuration to the next. Results for each configuration are presented and discussed. Combinations of enhanced internal film coefficients and high material thermal conductivity of copper and tungsten are predicted to maintain the maximum wall temperature for each concept within acceptable operating limits. The exception is the TD nickel material which is predicted to melt for most cases. The wide range of internal impingement film coefficients (based on correlations) for these conditions can lead to a significant uncertainty in expected leading-edge wall temperatures. The equivalent plastic strain, inherent in each configuration which results from the high thermal gradients, indicates a need for further cyclic analysis to determine component life.

  2. A Monte Carlo risk assessment model for acrylamide formation in French fries.

    PubMed

    Cummins, Enda; Butler, Francis; Gormley, Ronan; Brunton, Nigel

    2009-10-01

    The objective of this study is to estimate the likely human exposure to the group 2a carcinogen, acrylamide, from French fries by Irish consumers by developing a quantitative risk assessment model using Monte Carlo simulation techniques. Various stages in the French-fry-making process were modeled from initial potato harvest, storage, and processing procedures. The model was developed in Microsoft Excel with the @Risk add-on package. The model was run for 10,000 iterations using Latin hypercube sampling. The simulated mean acrylamide level in French fries was calculated to be 317 microg/kg. It was found that females are exposed to smaller levels of acrylamide than males (mean exposure of 0.20 microg/kg bw/day and 0.27 microg/kg bw/day, respectively). Although the carcinogenic potency of acrylamide is not well known, the simulated probability of exceeding the average chronic human dietary intake of 1 microg/kg bw/day (as suggested by WHO) was 0.054 and 0.029 for males and females, respectively. A sensitivity analysis highlighted the importance of the selection of appropriate cultivars with known low reducing sugar levels for French fry production. Strict control of cooking conditions (correlation coefficient of 0.42 and 0.35 for frying time and temperature, respectively) and blanching procedures (correlation coefficient -0.25) were also found to be important in ensuring minimal acrylamide formation.

  3. Weak data do not make a free lunch, only a cheap meal

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Luo, Zhipu; Rajashankar, Kanagalaghatta; Dauter, Zbigniew

    2014-01-17

    Four data sets were processed at resolutions significantly exceeding the criteria traditionally used for estimating the diffraction data resolution limit. The analysis of these data and the corresponding model-quality indicators suggests that the criteria of resolution limits widely adopted in the past may be somewhat conservative. Various parameters, such asR mergeandI/σ(I), optical resolution and the correlation coefficients CC 1/2and CC*, can be used for judging the internal data quality, whereas the reliability factorsRandR freeas well as the maximum-likelihood target values and real-space map correlation coefficients can be used to estimate the agreement between the data and the refined model. However,more » none of these criteria provide a reliable estimate of the data resolution cutoff limit. The analysis suggests that extension of the maximum resolution by about 0.2 Å beyond the currently adopted limit where theI/σ(I) value drops to 2.0 does not degrade the quality of the refined structural models, but may sometimes be advantageous. Such an extension may be particularly beneficial for significantly anisotropic diffraction. Extension of the maximum resolution at the stage of data collection and structure refinement is cheap in terms of the required effort and is definitely more advisable than accepting a too conservative resolution cutoff, which is unfortunately quite frequent among the crystal structures deposited in the Protein Data Bank.« less

  4. Development of the Chinese version of the Hospital Autonomy Questionnaire: a cross-sectional study in Guangdong Province

    PubMed Central

    Liu, Zifeng; Yuan, Lianxiong; Huang, Yixiang; Zhang, Lingling; Luo, Futian

    2016-01-01

    Objective We aimed to develop a questionnaire for quantitative evaluation of the autonomy of public hospitals in China. Method An extensive literature review was conducted to select possible items for inclusion in the questionnaire, which was then reviewed by 5 experts. After a two-round Delphi method, we distributed the questionnaire to 404 secondary and tertiary hospitals in Guangdong Province, China, and 379 completed questionnaires were collected. The final questionnaire was then developed on the basis of the results of exploratory and confirmatory factor analysis. Results Analysis suggested that all internal consistency reliabilities exceeded the minimum reliability standard of 0.70 for the α coefficient. The overall scale coefficient was 0.87, and 6 subscale coefficients were 0.92 (strategic management), 0.81 (budget and expenditure), 0.85 (financing), 0.75 (financing, medical management), 0.86 (human resources) and 0.86 (accountability). Correlation coefficients between and among items and their hypothesised subscales were higher than those with other subscales. The value of average variance extracted (AVE) was higher than 0.5, the value of construct reliability (CR) was higher than 0.7, and the square roots of the AVE of each subscale were larger than the correlation of the specific subscale with the other subscales, supporting the convergent and discriminant validity of the Chinese version of the Hospital Autonomy Questionnaire (CVHAQ). The model fit indices were all acceptable: χ2/df=1.73, Goodness of Fit Index (GFI) = 0.93, Adjusted Goodness of Fit Index (AGFI) = 0.91, Non-Normed Fit Index (NNFI) = 0.96, Comparative Fit Index (CFI) = 0.97, Root Mean Square Error of Approximation (RMSEA) = 0.04, Standardised Root Mean Square Residual (SRMR) = 0.07. Conclusions This study demonstrated the reliability and validity of a CVHAQ and provides a quantitative method for the assessment of hospital autonomy. PMID:26911587

  5. Cluster-cluster correlations and constraints on the correlation hierarchy

    NASA Technical Reports Server (NTRS)

    Hamilton, A. J. S.; Gott, J. R., III

    1988-01-01

    The hypothesis that galaxies cluster around clusters at least as strongly as they cluster around galaxies imposes constraints on the hierarchy of correlation amplitudes in hierachical clustering models. The distributions which saturate these constraints are the Rayleigh-Levy random walk fractals proposed by Mandelbrot; for these fractal distributions cluster-cluster correlations are all identically equal to galaxy-galaxy correlations. If correlation amplitudes exceed the constraints, as is observed, then cluster-cluster correlations must exceed galaxy-galaxy correlations, as is observed.

  6. Reliability and validity of the Iranian version of the Pediatric Quality of Life Inventory™ 4.0 Generic Core Scales in adolescents.

    PubMed

    Amiri, Parisa; M Ardekani, Emad; Jalali-Farahani, Sara; Hosseinpanah, Farhad; Varni, James W; Ghofranipour, Fazlollah; Montazeri, Ali; Azizi, Fereidoun

    2010-12-01

    The objective of this study was to investigate the reliability and validity of the Iranian version of the Pediatric Quality of Life Inventory™ 4.0 (PedsQL™ 4.0) Generic Core Scales in adolescents After linguistic validation, the Iranian version of the PedsQL™ 4.0 was completed by 848 healthy and 26 chronically ill adolescents aged 13-18 years and their parents. The internal consistency as measured by Cronbach's alpha coefficients exceeded the minimum reliability standard of .70. No floor effects were observed. Ceiling effects detected ranged from 1.5% for adolescent self-report total scale score to 42.2% for self-report social functioning. All monotrait-multimethod correlations were higher than multitrait-multimethod correlations. The intraclass correlation coefficients (ICC) between adolescent self-report and parent proxy-report showed good to excellent agreement. Exploratory factor analysis supported mainly comparable results with the original US English dialect version. The results of the confirmatory factor analysis for 5-factor models for both self-report and proxy-report indicated acceptable fit for the proposed models. Regarding gender and health status, as hypothesized from previous studies, girls reported lower health-related quality of life than boys on the total score, physical and emotional functioning, and healthy adolescents reported significantly higher health-related quality of life than those with chronic illnesses. The findings support the initial reliability and validity of the Iranian version of the PedsQL™ 4.0 as a generic instrument to measure HRQOL of adolescents in Iran.

  7. Changes in precipitation recycling over arid regions in the Northern Hemisphere

    NASA Astrophysics Data System (ADS)

    Li, Ruolin; Wang, Chenghai; Wu, Di

    2018-01-01

    Changes of precipitation recycling (PR) in Northern Hemisphere from 1981 to 2010 are investigated using a water recycling model. The temporal and spatial characteristics of recycling in arid regions are analyzed. The results show that the regional precipitation recycling ratio (PRR) in arid regions is larger than in wet regions. PRR in arid regions has obvious seasonal variation, ranging from more than 25 % to less than 1 %. Furthermore, in arid regions, PRR is significantly negatively correlated with precipitation (correlation coefficient r = -0.5, exceeding the 99 % significance level). Moreover, the trend of PRR is related to changes in precipitation in two ways. PRR decreases with increasing precipitation in North Africa, which implies that less locally evaporated vapor converts into actual precipitation. However, in Asian arid regions, the PRR increases as precipitation reduces, which implies that more locally evaporated vapor converts into rainfall. Further, as PRR mainly depends on evapotranspiration, the PRR trend in Asian arid regions develops as temperature increases and more evaporated vapor enters the atmosphere to offset the reduced rainfall.

  8. Comparability of a short food frequency questionnaire to assess diet quality: the DISCOVER study.

    PubMed

    Dehghan, Mahshid; Ge, Yipeng; El Sheikh, Wala; Bawor, Monica; Rangarajan, Sumathy; Dennis, Brittany; Vair, Judith; Sholer, Heather; Hutchinson, Nichole; Iordan, Elizabeth; Mackie, Pam; Samaan, Zainab

    2017-09-01

    This study aims to assess comparability of a short food frequency questionnaire (SFFQ) used in the Determinants of Suicide: Conventional and Emergent Risk Study (DISCOVER Study) with a validated comprehensive FFQ (CFFQ). A total of 127 individuals completed SFFQ and CFFQ. Healthy eating was measured using Healthy Eating Score (HES). Estimated food intake and healthy eating assessed by SFFQ was compared with the CFFQ. For most food groups and HES, the highest Spearman's rank correlation coefficients between the two FFQs were r > .60. For macro-nutrients, the correlations exceeded 0.4. Cross-classification of quantile analysis showed that participants were classified between 46% and 81% into the exact same quantiles, while 10% or less were misclassified into opposite quantiles. The Bland-Altman plots showed an acceptable level of agreement between the two dietary measurement methods. The SFFQ can be used for Canadian with psychiatric disorders to rank them based on their dietary intake.

  9. Identification of Correlated GRACE Monthly Harmonic Coefficients Using Pattern Recognition and Neural Networks

    NASA Astrophysics Data System (ADS)

    Piretzidis, D.; Sra, G.; Sideris, M. G.

    2016-12-01

    This study explores new methods for identifying correlation errors in harmonic coefficients derived from monthly solutions of the Gravity Recovery and Climate Experiment (GRACE) satellite mission using pattern recognition and neural network algorithms. These correlation errors are evidenced in the differences between monthly solutions and can be suppressed using a de-correlation filter. In all studies so far, the implementation of the de-correlation filter starts from a specific minimum order (i.e., 11 for RL04 and 38 for RL05) until the maximum order of the monthly solution examined. This implementation method has two disadvantages, namely, the omission of filtering correlated coefficients of order less than the minimum order and the filtering of uncorrelated coefficients of order higher than the minimum order. In the first case, the filtered solution is not completely free of correlated errors, whereas the second case results in a monthly solution that suffers from loss of geophysical signal. In the present study, a new method of implementing the de-correlation filter is suggested, by identifying and filtering only the coefficients that show indications of high correlation. Several numerical and geometric properties of the harmonic coefficient series of all orders are examined. Extreme cases of both correlated and uncorrelated coefficients are selected, and their corresponding properties are used to train a two-layer feed-forward neural network. The objective of the neural network is to identify and quantify the correlation by providing the probability of an order of coefficients to be correlated. Results show good performance of the neural network, both in the validation stage of the training procedure and in the subsequent use of the trained network to classify independent coefficients. The neural network is also capable of identifying correlated coefficients even when a small number of training samples and neurons are used (e.g.,100 and 10, respectively).

  10. Validation of a scale for assessing attitudes towards outcomes of genetic cancer testing among primary care providers and breast specialists

    PubMed Central

    N’Diaye, Khadim; Evans, D. Gareth; Harris, Hilary; Tibben, Aad; van Asperen, Christi; Schmidtke, Joerg; Nippert, Irmgard; Mancini, Julien; Julian-Reynier, Claire

    2017-01-01

    Objective To develop a generic scale for assessing attitudes towards genetic testing and to psychometrically assess these attitudes in the context of BRCA1/2 among a sample of French general practitioners, breast specialists and gyneco-obstetricians. Study design and setting Nested within the questionnaire developed for the European InCRisC (International Cancer Risk Communication Study) project were 14 items assessing expected benefits (8 items) and drawbacks (6 items) of the process of breast/ovarian genetic cancer testing (BRCA1/2). Another item assessed agreement with the statement that, overall, the expected health benefits of BRCA1/2 testing exceeded its drawbacks, thereby justifying its prescription. The questionnaire was mailed to a sample of 1,852 French doctors. Of these, 182 breast specialists, 275 general practitioners and 294 gyneco-obstetricians completed and returned the questionnaire to the research team. Principal Component Analysis, Cronbach’s α coefficient, and Pearson’s correlation coefficients were used in the statistical analyses of collected data. Results Three dimensions emerged from the respondents’ responses, and were classified under the headings: “Anxiety, Conflict and Discrimination”, “Risk Information”, and “Prevention and Surveillance”. Cronbach’s α coefficient for the 3 dimensions was 0.79, 0.76 and 0.62, respectively, and each dimension exhibited strong correlation with the overall indicator of agreement (criterion validity). Conclusions The validation process of the 15 items regarding BRCA1/2 testing revealed satisfactory psychometric properties for the creation of a new scale entitled the Attitudes Towards Genetic Testing for BRCA1/2 (ATGT-BRCA1/2) Scale. Further testing is required to confirm the validity of this tool which could be used generically in other genetic contexts. PMID:28570656

  11. Diagnosing cysts with correlation coefficient images from 2-dimensional freehand elastography.

    PubMed

    Booi, Rebecca C; Carson, Paul L; O'Donnell, Matthew; Richards, Michael S; Rubin, Jonathan M

    2007-09-01

    We compared the diagnostic potential of using correlation coefficient images versus elastograms from 2-dimensional (2D) freehand elastography to characterize breast cysts. In this preliminary study, which was approved by the Institutional Review Board and compliant with the Health Insurance Portability and Accountability Act, we imaged 4 consecutive human subjects (4 cysts, 1 biopsy-verified benign breast parenchyma) with freehand 2D elastography. Data were processed offline with conventional 2D phase-sensitive speckle-tracking algorithms. The correlation coefficient in the cyst and surrounding tissue was calculated, and appearances of the cysts in the correlation coefficient images and elastograms were compared. The correlation coefficient in the cysts was considerably lower (14%-37%) than in the surrounding tissue because of the lack of sufficient speckle in the cysts, as well as the prominence of random noise, reverberations, and clutter, which decorrelated quickly. Thus, the cysts were visible in all correlation coefficient images. In contrast, the elastograms associated with these cysts each had different elastographic patterns. The solid mass in this study did not have the same high decorrelation rate as the cysts, having a correlation coefficient only 2.1% lower than that of surrounding tissue. Correlation coefficient images may produce a more direct, reliable, and consistent method for characterizing cysts than elastograms.

  12. Flight Investigation at High Speeds of Profile Drag of Wing of a P-47D Airplane Having Production Surfaces Covered with Camouflage Paint

    NASA Technical Reports Server (NTRS)

    Daum, Fred L.; Zalovcik, John A.

    1946-01-01

    Wing section outboard of flap was tested by wake surveys in Mach range of 0.25 - 0.78 and lift coefficient range 0.06 - 0.69. Results indicated that minimum profile-drag coefficient of 0.0097 was attained for lift coefficients from 0.16 to 0.25 at Mach less than 0.67. Below Mach number at which compressibility shock occurred, variations in Mach of 0.2 had negligible effect on profile drag coefficient. Shock was not evident until critical Mach was exceeded by 0.025.

  13. Piezoelectric shear wave resonator and method of making same

    DOEpatents

    Wang, Jin S.; Lakin, Kenneth M.; Landin, Allen R.

    1988-01-01

    An acoustic shear wave resonator comprising a piezoelectric film having its C-axis substantially inclined from the film normal such that the shear wave coupling coefficient significantly exceeds the longitudinal wave coupling coefficient, whereby the film is capable of shear wave resonance, and means for exciting said film to resonate. The film is prepared by deposition in a dc planar magnetron sputtering system to which a supplemental electric field is applied. The resonator structure may also include a semiconductor material having a positive temperature coefficient of resonance such that the resonator has a temperature coefficient of resonance approaching 0 ppm/.degree.C.

  14. Method of making a piezoelectric shear wave resonator

    DOEpatents

    Wang, Jin S.; Lakin, Kenneth M.; Landin, Allen R.

    1987-02-03

    An acoustic shear wave resonator comprising a piezoelectric film having its C-axis substantially inclined from the film normal such that the shear wave coupling coefficient significantly exceeds the longitudinal wave coupling coefficient, whereby the film is capable of shear wave resonance, and means for exciting said film to resonate. The film is prepared by deposition in a dc planar magnetron sputtering system to which a supplemental electric field is applied. The resonator structure may also include a semiconductor material having a positive temperature coefficient of resonance such that the resonator has a temperature coefficient of resonance approaching 0 ppm/.degree.C.

  15. A New Methodology of Spatial Cross-Correlation Analysis

    PubMed Central

    Chen, Yanguang

    2015-01-01

    Spatial correlation modeling comprises both spatial autocorrelation and spatial cross-correlation processes. The spatial autocorrelation theory has been well-developed. It is necessary to advance the method of spatial cross-correlation analysis to supplement the autocorrelation analysis. This paper presents a set of models and analytical procedures for spatial cross-correlation analysis. By analogy with Moran’s index newly expressed in a spatial quadratic form, a theoretical framework is derived for geographical cross-correlation modeling. First, two sets of spatial cross-correlation coefficients are defined, including a global spatial cross-correlation coefficient and local spatial cross-correlation coefficients. Second, a pair of scatterplots of spatial cross-correlation is proposed, and the plots can be used to visually reveal the causality behind spatial systems. Based on the global cross-correlation coefficient, Pearson’s correlation coefficient can be decomposed into two parts: direct correlation (partial correlation) and indirect correlation (spatial cross-correlation). As an example, the methodology is applied to the relationships between China’s urbanization and economic development to illustrate how to model spatial cross-correlation phenomena. This study is an introduction to developing the theory of spatial cross-correlation, and future geographical spatial analysis might benefit from these models and indexes. PMID:25993120

  16. A new methodology of spatial cross-correlation analysis.

    PubMed

    Chen, Yanguang

    2015-01-01

    Spatial correlation modeling comprises both spatial autocorrelation and spatial cross-correlation processes. The spatial autocorrelation theory has been well-developed. It is necessary to advance the method of spatial cross-correlation analysis to supplement the autocorrelation analysis. This paper presents a set of models and analytical procedures for spatial cross-correlation analysis. By analogy with Moran's index newly expressed in a spatial quadratic form, a theoretical framework is derived for geographical cross-correlation modeling. First, two sets of spatial cross-correlation coefficients are defined, including a global spatial cross-correlation coefficient and local spatial cross-correlation coefficients. Second, a pair of scatterplots of spatial cross-correlation is proposed, and the plots can be used to visually reveal the causality behind spatial systems. Based on the global cross-correlation coefficient, Pearson's correlation coefficient can be decomposed into two parts: direct correlation (partial correlation) and indirect correlation (spatial cross-correlation). As an example, the methodology is applied to the relationships between China's urbanization and economic development to illustrate how to model spatial cross-correlation phenomena. This study is an introduction to developing the theory of spatial cross-correlation, and future geographical spatial analysis might benefit from these models and indexes.

  17. Random matrix theory analysis of cross-correlations in the US stock market: Evidence from Pearson’s correlation coefficient and detrended cross-correlation coefficient

    NASA Astrophysics Data System (ADS)

    Wang, Gang-Jin; Xie, Chi; Chen, Shou; Yang, Jiao-Jiao; Yang, Ming-Yan

    2013-09-01

    In this study, we first build two empirical cross-correlation matrices in the US stock market by two different methods, namely the Pearson’s correlation coefficient and the detrended cross-correlation coefficient (DCCA coefficient). Then, combining the two matrices with the method of random matrix theory (RMT), we mainly investigate the statistical properties of cross-correlations in the US stock market. We choose the daily closing prices of 462 constituent stocks of S&P 500 index as the research objects and select the sample data from January 3, 2005 to August 31, 2012. In the empirical analysis, we examine the statistical properties of cross-correlation coefficients, the distribution of eigenvalues, the distribution of eigenvector components, and the inverse participation ratio. From the two methods, we find some new results of the cross-correlations in the US stock market in our study, which are different from the conclusions reached by previous studies. The empirical cross-correlation matrices constructed by the DCCA coefficient show several interesting properties at different time scales in the US stock market, which are useful to the risk management and optimal portfolio selection, especially to the diversity of the asset portfolio. It will be an interesting and meaningful work to find the theoretical eigenvalue distribution of a completely random matrix R for the DCCA coefficient because it does not obey the Marčenko-Pastur distribution.

  18. Polymer chain collapse induced by many-body dipole correlations.

    PubMed

    Budkov, Yu A; Kalikin, N N; Kolesnikov, A L

    2017-04-01

    We present a simple analytical theory of a flexible polymer chain dissolved in a good solvent, carrying permanent freely oriented dipoles on the monomers. We take into account the dipole correlations within the random phase approximation (RPA), as well as a dielectric heterogeneity in the internal polymer volume relative to the bulk solution. We demonstrate that the dipole correlations of monomers can be taken into account as pairwise ones only when the polymer chain is in a coil conformation. In this case the dipole correlations manifest themselves through the Keesom interactions of the permanent dipoles. On the other hand, the dielectric heterogeneity effect (dielectric mismatch effect) leads to the effective interaction between the monomers of the polymeric coil. Both of these effects can be taken into account by renormalizing the second virial coefficient of the monomer-monomer volume interactions. We establish that in the case when the solvent dielectric permittivity exceeds the dielectric permittivity of the polymeric material, the dielectric mismatch effect competes with the dipole attractive interactions, leading to polymer coil expansion. In the opposite case, both the dielectric mismatch effect and the dipole attractive interaction lead to the polymer coil collapse. We analyse the coil-globule transition caused by the dipole correlations of monomers within the many-body theory. We demonstrate that accounting for the dipole correlations higher than the pairwise ones smooths this pure electrostatics driven coil-globule transition of the polymer chain.

  19. Restoring method for missing data of spatial structural stress monitoring based on correlation

    NASA Astrophysics Data System (ADS)

    Zhang, Zeyu; Luo, Yaozhi

    2017-07-01

    Long-term monitoring of spatial structures is of great importance for the full understanding of their performance and safety. The missing part of the monitoring data link will affect the data analysis and safety assessment of the structure. Based on the long-term monitoring data of the steel structure of the Hangzhou Olympic Center Stadium, the correlation between the stress change of the measuring points is studied, and an interpolation method of the missing stress data is proposed. Stress data of correlated measuring points are selected in the 3 months of the season when missing data is required for fitting correlation. Data of daytime and nighttime are fitted separately for interpolation. For a simple linear regression when single point's correlation coefficient is 0.9 or more, the average error of interpolation is about 5%. For multiple linear regression, the interpolation accuracy is not significantly increased after the number of correlated points is more than 6. Stress baseline value of construction step should be calculated before interpolating missing data in the construction stage, and the average error is within 10%. The interpolation error of continuous missing data is slightly larger than that of the discrete missing data. The data missing rate of this method should better not exceed 30%. Finally, a measuring point's missing monitoring data is restored to verify the validity of the method.

  20. Relation between aerosol particles and their optical properties: a case study for São Paulo-Brazil

    NASA Astrophysics Data System (ADS)

    Miranda, Regina; Andrade, Maria de Fatima

    2013-04-01

    Brazil has a territory of 8.5 million km2 and a population of more than 160 million inhabitants, distributed throughout 26 states. Brazillian capital-cities with millions inhabitants and vehicles have several problems concerning air pollution. São Paulo, capital of São Paulo State, with more than 19 million inhabitants, 7 million vehicles, as well as the major industrial and technological park of the country, has high concentrations of air pollutants, especially in the winter. Air pollution, high building density, and a lack of green areas, combined with the proliferation of asphalt and concrete surfaces, have resulted in a greater number of urban heat island effects, fewer drizzle events, and rainfall events of greater intensity. São Paulo has an extensive air quality monitoring network, which has shown that ozone levels often exceed the NAAQS limit during spring and summer, and that concentrations of inhalable particles exceed the NAAQS limit mainly during the winter, from June to August. Aerosols are produced by a variety of processes, creating differences in their physicochemical properties and hence in their ability to scatter and absorb solar radiation. For most urban areas in Brazil, vehicles are considered the principal source of particles emitted to the atmosphere. Particles have been monitored in the winter of 2012 in São Paulo using a MOUDI (Micro Orifice Uniform Deposit Impactor), in order to have the mass distribution of the aerosol. The concentrations of coarse particles can still be larger than those of fine particles, although the difference between both has become smaller than in the past. The samples collected were analyzed by gravimetry for mass concentration, optical reflectance for Black Carbon concentration and X-ray Fluorescence for elementar characterization. Optical properties were obtained from Aeronet (Aerosol Robotic Network, http://aeronet.gsfc.nasa.gov/) for São Paulo city. It was found that a high fraction of elements was derived from mineral dust (Al, Si, Ca, Fe), anthropogenic particles and the burning of diesel (S), as well as from industries and residual oil combustion. Considering the trace element values obtained through EDXRF analysis, Angstron coefficients and Aerosol Optical Thickness (AOT 500 nm) were correlated (Pearson Correlation) to particulate and chemical elements. Soil elements have a positive correlation, fine particles are strong correlated to AOT. Elements like Fe, Si and Ca are usually related to larger particles and lower Angstron coefficients.

  1. Photoacoustic Spectroscopy as a Non-destructive Tool for Quantification of Pesticide Residue in Apple Cuticle

    NASA Astrophysics Data System (ADS)

    Liu, Lixian; Wang, Yafei; Gao, Chunming; Huan, Huiting; Zhao, Binxing; Yan, Laijun

    2015-06-01

    Photoacoustic spectroscopy (PAS), the non-destructive method to detect residue of dimethyl-dichloro-vinyl-phosphate (DDVP) pesticide in a cuticle of apple, is described. After constructing the PA experimental setup and identifying three characteristic peaks of DDVP in the near ultraviolet region, the PA spectra of an apple cuticle contaminated with DDVP were collected. The artificial neural network method was then applied to analyze data quantitatively. The results show a correlation coefficient exceeding 0.99 and a detection limit of 0.2 ppm, which is within the national food safety standard for maximum residue limits for pesticides in food (GB 2763-2012). This fact and the non-destructive character of PAS make the approach promising for detection of pesticide residue in fruits.

  2. Feasibility of a Respiratory Movement Evaluation Tool to Quantify Thoracoabdominal Movement for Neuromuscular Diseases.

    PubMed

    Liu, Fumio; Kawakami, Michiyuki; Tamura, Kimimasa; Taki, Yoshihito; Shimizu, Katsumi; Otsuka, Tomoyoshi; Tsuji, Tetsuya; Miyata, Chieko; Tashiro, Syoichi; Wada, Ayako; Mizuno, Katsuhiro; Aoki, Yoshimitsu; Liu, Meigen

    2017-04-01

    An objective method to evaluate thoracoabdominal movement is needed in daily clinical practice to detect patients at risk of hypoventilation and to allow for timely interventions in neuromuscular diseases. The clinical feasibility, reliability, and validity of a newly developed method for quantifying respiratory movement using fiber grating sensors, called the Respiratory Movement Evaluation Tool (RMET), was evaluated. The time needed to measure respiratory movement and the usability of the measurement were determined by 5 clinicians using the Quebec User Evaluation of Satisfaction with Assistive Technology (QUEST) 2.0 questionnaire. Thoracoabdominal movement was measured using RMET 3 times in 10 healthy subjects to evaluate intraclass correlation coefficients (ICC). The subjects were encouraged to breathe 10 times while voluntarily changing the amount of air during ventilation simultaneously with the RMET and a spirometer, and their correlations were evaluated to test validity using Pearson's product-moment correlation coefficients. The same measurements were also performed in 10 subjects with Duchenne muscular dystrophy. Real-time recordings of thoracoabdominal movements were obtained over a mean time of 374 ± 23.9 s. With QUEST 2.0, the median score of each item exceeded 3 (more or less satisfied). In healthy subjects, ICC(1,1) ranged from 0.82 to 0.99, and ICC(2,1) ranged from 0.83 to 0.97. Significant correlations were observed between the respiratory amplitudes measured with RMET, and the amount of air during ventilation was measured with a spirometer (r = 0.995, P < .001). In subjects with Duchenne muscular dystrophy, ICC(1,1) ranged from 0.87 to 0.97, and ICC(2,1) ranged from 0.84 to 0.99. The respiratory amplitudes measured with RMET correlated significantly with the amount of air during ventilation with a spirometer (r = 0.957, P < .001). We developed a novel method of quantifying respiratory movement called RMET that was feasible to use in daily clinical practice. Copyright © 2017 by Daedalus Enterprises.

  3. Identifying presence of correlated errors in GRACE monthly harmonic coefficients using machine learning algorithms

    NASA Astrophysics Data System (ADS)

    Piretzidis, Dimitrios; Sra, Gurveer; Karantaidis, George; Sideris, Michael G.

    2017-04-01

    A new method for identifying correlated errors in Gravity Recovery and Climate Experiment (GRACE) monthly harmonic coefficients has been developed and tested. Correlated errors are present in the differences between monthly GRACE solutions, and can be suppressed using a de-correlation filter. In principle, the de-correlation filter should be implemented only on coefficient series with correlated errors to avoid losing useful geophysical information. In previous studies, two main methods of implementing the de-correlation filter have been utilized. In the first one, the de-correlation filter is implemented starting from a specific minimum order until the maximum order of the monthly solution examined. In the second one, the de-correlation filter is implemented only on specific coefficient series, the selection of which is based on statistical testing. The method proposed in the present study exploits the capabilities of supervised machine learning algorithms such as neural networks and support vector machines (SVMs). The pattern of correlated errors can be described by several numerical and geometric features of the harmonic coefficient series. The features of extreme cases of both correlated and uncorrelated coefficients are extracted and used for the training of the machine learning algorithms. The trained machine learning algorithms are later used to identify correlated errors and provide the probability of a coefficient series to be correlated. Regarding SVMs algorithms, an extensive study is performed with various kernel functions in order to find the optimal training model for prediction. The selection of the optimal training model is based on the classification accuracy of the trained SVM algorithm on the same samples used for training. Results show excellent performance of all algorithms with a classification accuracy of 97% - 100% on a pre-selected set of training samples, both in the validation stage of the training procedure and in the subsequent use of the trained algorithms to classify independent coefficients. This accuracy is also confirmed by the external validation of the trained algorithms using the hydrology model GLDAS NOAH. The proposed method meet the requirement of identifying and de-correlating only coefficients with correlated errors. Also, there is no need of applying statistical testing or other techniques that require prior de-correlation of the harmonic coefficients.

  4. Factors That Attenuate the Correlation Coefficient and Its Analogs.

    ERIC Educational Resources Information Center

    Dolenz, Beverly

    The correlation coefficient is an integral part of many other statistical techniques (analysis of variance, t-tests, etc.), since all analytic methods are actually correlational (G. V. Glass and K. D. Hopkins, 1984). The correlation coefficient is a statistical summary that represents the degree and direction of relationship between two variables.…

  5. Lake-level frequency analysis for Devils Lake, North Dakota

    USGS Publications Warehouse

    Wiche, Gregg J.; Vecchia, Aldo V.

    1996-01-01

    Two approaches were used to estimate future lake-level probabilities for Devils Lake. The first approach is based on an annual lake-volume model, and the second approach is based on a statistical water mass-balance model that generates seasonal lake volumes on the basis of seasonal precipitation, evaporation, and inflow. Autoregressive moving average models were used to model the annual mean lake volume and the difference between the annual maximum lake volume and the annual mean lake volume. Residuals from both models were determined to be uncorrelated with zero mean and constant variance. However, a nonlinear relation between the residuals of the two models was included in the final annual lakevolume model.Because of high autocorrelation in the annual lake levels of Devils Lake, the annual lake-volume model was verified using annual lake-level changes. The annual lake-volume model closely reproduced the statistics of the recorded lake-level changes for 1901-93 except for the skewness coefficient. However, the model output is less skewed than the data indicate because of some unrealistically large lake-level declines. The statistical water mass-balance model requires as inputs seasonal precipitation, evaporation, and inflow data for Devils Lake. Analysis of annual precipitation, evaporation, and inflow data for 1950-93 revealed no significant trends or long-range dependence so the input time series were assumed to be stationary and short-range dependent.Normality transformations were used to approximately maintain the marginal probability distributions; and a multivariate, periodic autoregressive model was used to reproduce the correlation structure. Each of the coefficients in the model is significantly different from zero at the 5-percent significance level. Coefficients relating spring inflow from one year to spring and fall inflows from the previous year had the largest effect on the lake-level frequency analysis.Inclusion of parameter uncertainty in the model for generating precipitation, evaporation, and inflow indicates that the upper lake-level exceedance levels from the water mass-balance model are particularly sensitive to parameter uncertainty. The sensitivity in the upper exceedance levels was caused almost entirely by uncertainty in the fitted probability distributions of the quarterly inflows. A method was developed for using long-term streamflow data for the Red River of the North at Grand Forks to reduce the variance in the estimated mean.Comparison of the annual lake-volume model and the water mass-balance model indicates the upper exceedance levels of the water mass-balance model increase much more rapidly than those of the annual lake-volume model. As an example, for simulation year 5, the 99-percent exceedance for the lake level is 1,417.6 feet above sea level for the annual lake-volume model and 1,423.2 feet above sea level for the water mass-balance model. The rapid increase is caused largely by the record precipitation and inflow in the summer and fall of 1993. Because the water mass-balance model produces lake-level traces that closely match the hydrology of Devils Lake, the water mass-balance model is superior to the annual lake-volume model for computing exceedance levels for the 50-year planning horizon.

  6. Lake-level frequency analysis for Devils Lake, North Dakota

    USGS Publications Warehouse

    Wiche, Gregg J.; Vecchia, Aldo V.

    1995-01-01

    Two approaches were used to estimate future lake-level probabilities for Devils Lake. The first approach is based on an annual lake-volume model, and the second approach is based on a statistical water mass-balance model that generates seasonal lake volumes on the basis of seasonal precipitation, evaporation, and inflow.Autoregressive moving average models were used to model the annual mean lake volume and the difference between the annual maximum lake volume and the annual mean lake volume. Residuals from both models were determined to be uncorrelated with zero mean and constant variance. However, a nonlinear relation between the residuals of the two models was included in the final annual lake-volume model.Because of high autocorrelation in the annual lake levels of Devils Lake, the annual lakevolume model was verified using annual lake-level changes. The annual lake-volume model closely reproduced the statistics of the recorded lake-level changes for 1901-93 except for the skewness coefficient However, the model output is less skewed than the data indicate because of some unrealistically large lake-level declines.The statistical water mass-balance model requires as inputs seasonal precipitation, evaporation, and inflow data for Devils Lake. Analysis of annual precipitation, evaporation, and inflow data for 1950-93 revealed no significant trends or long-range dependence so the input time series were assumed to be stationary and short-range dependent.Normality transformations were used to approximately maintain the marginal probability distributions; and a multivariate, periodic autoregressive model was used to reproduce the correlation structure. Each of the coefficients in the model is significantly different from zero at the 5-percent significance level. Coefficients relating spring inflow from one year to spring and fall inflows from the previous year had the largest effect on the lake-level frequency analysis.Inclusion of parameter uncertainty in the model for generating precipitation, evaporation, and inflow indicates that the upper lake-level exceedance levels from the water mass-balance model are particularly sensitive to parameter uncertainty. The sensitivity in the upper exceedance levels was caused almost entirely by uncertainty in the fitted probability distributions of the quarterly inflows. A method was developed for using long-term streamflow data for the Red River of the North at Grand Forks to reduce the variance in the estimated mean. Comparison of the annual lake-volume model and the water mass-balance model indicates the upper exceedance levels of the water mass-balance model increase much more rapidly than those of the annual lake-volume model. As an example, for simulation year 5, the 99-percent exceedance for the lake level is 1,417.6 feet above sea level for the annual lake-volume model and 1,423.2 feet above sea level for the water mass-balance model. The rapid increase is caused largely by the record precipitation and inflow in the summer and fall of 1993. Because the water mass-balance model produces lake-level traces that closely match the hydrology of Devils Lake, the water mass-balance model is superior to the annual lake-volume model for computing exceedance levels for the 50-year planning horizon.

  7. Extrapolating MP2 and CCSD explicitly correlated correlation energies to the complete basis set limit with first and second row correlation consistent basis sets

    NASA Astrophysics Data System (ADS)

    Hill, J. Grant; Peterson, Kirk A.; Knizia, Gerald; Werner, Hans-Joachim

    2009-11-01

    Accurate extrapolation to the complete basis set (CBS) limit of valence correlation energies calculated with explicitly correlated MP2-F12 and CCSD(T)-F12b methods have been investigated using a Schwenke-style approach for molecules containing both first and second row atoms. Extrapolation coefficients that are optimal for molecular systems containing first row elements differ from those optimized for second row analogs, hence values optimized for a combined set of first and second row systems are also presented. The new coefficients are shown to produce excellent results in both Schwenke-style and equivalent power-law-based two-point CBS extrapolations, with the MP2-F12/cc-pV(D,T)Z-F12 extrapolations producing an average error of just 0.17 mEh with a maximum error of 0.49 for a collection of 23 small molecules. The use of larger basis sets, i.e., cc-pV(T,Q)Z-F12 and aug-cc-pV(Q,5)Z, in extrapolations of the MP2-F12 correlation energy leads to average errors that are smaller than the degree of confidence in the reference data (˜0.1 mEh). The latter were obtained through use of very large basis sets in MP2-F12 calculations on small molecules containing both first and second row elements. CBS limits obtained from optimized coefficients for conventional MP2 are only comparable to the accuracy of the MP2-F12/cc-pV(D,T)Z-F12 extrapolation when the aug-cc-pV(5+d)Z and aug-cc-pV(6+d)Z basis sets are used. The CCSD(T)-F12b correlation energy is extrapolated as two distinct parts: CCSD-F12b and (T). While the CCSD-F12b extrapolations with smaller basis sets are statistically less accurate than those of the MP2-F12 correlation energies, this is presumably due to the slower basis set convergence of the CCSD-F12b method compared to MP2-F12. The use of larger basis sets in the CCSD-F12b extrapolations produces correlation energies with accuracies exceeding the confidence in the reference data (also obtained in large basis set F12 calculations). It is demonstrated that the use of the 3C(D) Ansatz is preferred for MP2-F12 CBS extrapolations. Optimal values of the geminal Slater exponent are presented for the diagonal, fixed amplitude Ansatz in MP2-F12 calculations, and these are also recommended for CCSD-F12b calculations.

  8. [Evaluation and cumulative characteristics of heavy metals in soil-Uncaria rhynchophylla system of different functional areas].

    PubMed

    Zhang, Jia-Chun; Zeng, Xian-Ping; Zhang, Zhen-Ming; Lin, Shao-Xia; Zhang, Qing-Hai; Lin, Chang-Hu

    2016-10-01

    Soil and Uncaria rhynchophylla in different functional areas were selected for the study,the content of heavy metals such as As, Cd, Cu, Cr, Pb, and Hg in soil and U. rhynchophylla was discussed, the characteristics of their accumulation in the U.rhynchophylla was analyzed, the contamination levels of heavy metals in soil in different functional areas was evaluated. The results showed that content of Cu, As, Pb and Cr in soil was being cropland>woodland>wasteland, content of Cd was being woodland>cropland>wasteland, content of Hg was being cropland>woodland>wasteland. According to quality standard of soil environment, soil Cd in woodland, cropland and wasteland all exceeded the state-level standards, soil Cd in woodland exceeded the secondary standard, soil Hg in cropland and wasteland all exceeded the state-level standards. According to technical conditions of green food producing area, soil Cd in woodland exceeded the limit value of standard. According to Green Trade Standards of Importing Exporting Medicinal Plants Preparations,the content of heavy metals of U.rhynchophylla in cropland,woodland and wasteland were correspond to the specification. From the single factor pollution index, the soil in woodland was polluted by Cd. From the comprehensive pollution index, the soils in different functional areas were not contaminated by heavy metals. The enrichment coefficient of heavy metals such as As, Cu, Cr, and Pb in hook of U.rhynchophylla was being wasteland>woodland>cropland, the enrichment coefficient of Cu in hook of U. rhynchophylla in wasteland was more than 1. Except Cu, the enrichment coefficient of other heavy metals was low. Copyright© by the Chinese Pharmaceutical Association.

  9. ppcor: An R Package for a Fast Calculation to Semi-partial Correlation Coefficients.

    PubMed

    Kim, Seongho

    2015-11-01

    Lack of a general matrix formula hampers implementation of the semi-partial correlation, also known as part correlation, to the higher-order coefficient. This is because the higher-order semi-partial correlation calculation using a recursive formula requires an enormous number of recursive calculations to obtain the correlation coefficients. To resolve this difficulty, we derive a general matrix formula of the semi-partial correlation for fast computation. The semi-partial correlations are then implemented on an R package ppcor along with the partial correlation. Owing to the general matrix formulas, users can readily calculate the coefficients of both partial and semi-partial correlations without computational burden. The package ppcor further provides users with the level of the statistical significance with its test statistic.

  10. Optimal portfolio strategy with cross-correlation matrix composed by DCCA coefficients: Evidence from the Chinese stock market

    NASA Astrophysics Data System (ADS)

    Sun, Xuelian; Liu, Zixian

    2016-02-01

    In this paper, a new estimator of correlation matrix is proposed, which is composed of the detrended cross-correlation coefficients (DCCA coefficients), to improve portfolio optimization. In contrast to Pearson's correlation coefficients (PCC), DCCA coefficients acquired by the detrended cross-correlation analysis (DCCA) method can describe the nonlinear correlation between assets, and can be decomposed in different time scales. These properties of DCCA make it possible to improve the investment effect and more valuable to investigate the scale behaviors of portfolios. The minimum variance portfolio (MVP) model and the Mean-Variance (MV) model are used to evaluate the effectiveness of this improvement. Stability analysis shows the effect of two kinds of correlation matrices on the estimation error of portfolio weights. The observed scale behaviors are significant to risk management and could be used to optimize the portfolio selection.

  11. Relationships among the slopes of lines derived from various data analysis techniques and the associated correlation coefficient

    NASA Technical Reports Server (NTRS)

    Cohen, S. C.

    1980-01-01

    A technique for fitting a straight line to a collection of data points is given. The relationships between the slopes and correlation coefficients, and between the corresponding standard deviations and correlation coefficient are given.

  12. Correlation Between Minimum Apparent Diffusion Coefficient (ADCmin) and Tumor Cellularity: A Meta-analysis.

    PubMed

    Surov, Alexey; Meyer, Hans Jonas; Wienke, Andreas

    2017-07-01

    Diffusion-weighted imaging (DWI) is a magnetic resonance imaging (MRI) technique based on measure of water diffusion that can provide information about tissue microstructure, especially about cell count. Increase of cell density induces restriction of water diffusion and decreases apparent diffusion coefficient (ADC). ADC can be divided into three sub-parameters: ADC minimum or ADC min , mean ADC or ADC mean and ADC maximum or ADC max Some studies have suggested that ADC min shows stronger correlations with cell count in comparison to other ADC fractions and may be used as a parameter for estimation of tumor cellularity. The aim of the present meta-analysis was to summarize correlation coefficients between ADC min and cellularity in different tumors based on large patient data. For this analysis, MEDLINE database was screened for associations between ADC and cell count in different tumors up to September 2016. For this work, only data regarding ADC min were included. Overall, 12 publications with 317 patients were identified. Spearman's correlation coefficient was used to analyze associations between ADC min and cellularity. The reported Pearson correlation coefficients in some publications were converted into Spearman correlation coefficients. The pooled correlation coefficient for all included studies was ρ=-0.59 (95% confidence interval (CI)=-0.72 to -0.45), heterogeneity Tau 2 =0.04 (p<0.0001), I 2 =73%, test for overall effect Z=8.67 (p<0.00001). ADC min correlated moderately with tumor cellularity. The calculated correlation coefficient is not stronger in comparison to the reported coefficient for ADC mean and, therefore, ADC min does not represent a better means to reflect cellularity. Copyright© 2017, International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.

  13. Correlation of human papillomavirus status with apparent diffusion coefficient of diffusion-weighted MRI in head and neck squamous cell carcinomas.

    PubMed

    Driessen, Juliette P; van Bemmel, Alexander J M; van Kempen, Pauline M W; Janssen, Luuk M; Terhaard, Chris H J; Pameijer, Frank A; Willems, Stefan M; Stegeman, Inge; Grolman, Wilko; Philippens, Marielle E P

    2016-04-01

    Identification of prognostic patient characteristics in head and neck squamous cell carcinoma (HNSCC) is of great importance. Human papillomavirus (HPV)-positive HNSCCs have favorable response to (chemo)radiotherapy. Apparent diffusion coefficient, derived from diffusion-weighted MRI, has also shown to predict treatment response. The purpose of this study was to evaluate the correlation between HPV status and apparent diffusion coefficient. Seventy-three patients with histologically proven HNSCC were retrospectively analyzed. Mean pretreatment apparent diffusion coefficient was calculated by delineation of total tumor volume on diffusion-weighted MRI. HPV status was analyzed and correlated to apparent diffusion coefficient. Six HNSCCs were HPV-positive. HPV-positive HNSCC showed significantly lower apparent diffusion coefficient compared to HPV-negative. This correlation was independent of other patient characteristics. In HNSCC, positive HPV status correlates with low mean apparent diffusion coefficient. The favorable prognostic value of low pretreatment apparent diffusion coefficient might be partially attributed to patients with a positive HPV status. © 2015 Wiley Periodicals, Inc. Head Neck 38: E613-E618, 2016. © 2015 Wiley Periodicals, Inc.

  14. Similarity analysis between chromosomes of Homo sapiens and monkeys with correlation coefficient, rank correlation coefficient and cosine similarity measures

    PubMed Central

    Someswara Rao, Chinta; Viswanadha Raju, S.

    2016-01-01

    In this paper, we consider correlation coefficient, rank correlation coefficient and cosine similarity measures for evaluating similarity between Homo sapiens and monkeys. We used DNA chromosomes of genome wide genes to determine the correlation between the chromosomal content and evolutionary relationship. The similarity among the H. sapiens and monkeys is measured for a total of 210 chromosomes related to 10 species. The similarity measures of these different species show the relationship between the H. sapiens and monkey. This similarity will be helpful at theft identification, maternity identification, disease identification, etc. PMID:26981409

  15. Similarity analysis between chromosomes of Homo sapiens and monkeys with correlation coefficient, rank correlation coefficient and cosine similarity measures.

    PubMed

    Someswara Rao, Chinta; Viswanadha Raju, S

    2016-03-01

    In this paper, we consider correlation coefficient, rank correlation coefficient and cosine similarity measures for evaluating similarity between Homo sapiens and monkeys. We used DNA chromosomes of genome wide genes to determine the correlation between the chromosomal content and evolutionary relationship. The similarity among the H. sapiens and monkeys is measured for a total of 210 chromosomes related to 10 species. The similarity measures of these different species show the relationship between the H. sapiens and monkey. This similarity will be helpful at theft identification, maternity identification, disease identification, etc.

  16. Reduction of predictive uncertainty in estimating irrigation water requirement through multi-model ensembles and ensemble averaging

    NASA Astrophysics Data System (ADS)

    Multsch, S.; Exbrayat, J.-F.; Kirby, M.; Viney, N. R.; Frede, H.-G.; Breuer, L.

    2015-04-01

    Irrigation agriculture plays an increasingly important role in food supply. Many evapotranspiration models are used today to estimate the water demand for irrigation. They consider different stages of crop growth by empirical crop coefficients to adapt evapotranspiration throughout the vegetation period. We investigate the importance of the model structural versus model parametric uncertainty for irrigation simulations by considering six evapotranspiration models and five crop coefficient sets to estimate irrigation water requirements for growing wheat in the Murray-Darling Basin, Australia. The study is carried out using the spatial decision support system SPARE:WATER. We find that structural model uncertainty among reference ET is far more important than model parametric uncertainty introduced by crop coefficients. These crop coefficients are used to estimate irrigation water requirement following the single crop coefficient approach. Using the reliability ensemble averaging (REA) technique, we are able to reduce the overall predictive model uncertainty by more than 10%. The exceedance probability curve of irrigation water requirements shows that a certain threshold, e.g. an irrigation water limit due to water right of 400 mm, would be less frequently exceeded in case of the REA ensemble average (45%) in comparison to the equally weighted ensemble average (66%). We conclude that multi-model ensemble predictions and sophisticated model averaging techniques are helpful in predicting irrigation demand and provide relevant information for decision making.

  17. Piezoelectric shear wave resonator and method of making same

    DOEpatents

    Wang, J.S.; Lakin, K.M.; Landin, A.R.

    1985-05-20

    An acoustic shear wave resonator comprising a piezoelectric film having its C-axis substantially inclined from the film normal such that the shear wave coupling coefficient significantly exceeds the longitudinal wave coupling coefficient, whereby the film is capable of shear wave resonance, and means for exciting said film to resonate. The film is prepared by deposition in a dc planar magnetron sputtering system to which a supplemental electric field is applied. The resonator structure may also include a semiconductor material having a positive temperature coefficient of resonance such that the resonator has a temperature coefficient of resonance approaching 0 ppM//sup 0/C.

  18. Piezoelectric shear wave resonator and method of making same

    DOEpatents

    Wang, J.S.; Lakin, K.M.; Landin, A.R.

    1983-10-25

    An acoustic shear wave resonator comprising a piezoelectric film having its C-axis substantially inclined from the film normal such that the shear wave coupling coefficient significantly exceeds the longitudinal wave coupling coefficient, whereby the film is capable of shear wave resonance, and means for exciting said film to resonate. The film is prepared by deposition in a dc planar magnetron sputtering system to which a supplemental electric field is applied. The resonator structure may also include a semiconductor material having a positive temperature coefficient of resonance such that the resonator has a temperature coefficient of resonance approaching 0 ppM//sup 0/C.

  19. Enhanced brainstem and cortical evoked response amplitudes: single-trial covariance analysis.

    PubMed

    Galbraith, G C

    2001-06-01

    The purpose of the present study was to develop analytic procedures that improve the definition of sensory evoked response components. Such procedures could benefit all recordings but would especially benefit difficult recordings where many trials are contaminated by muscle and movement artifacts. First, cross-correlation and latency adjustment analyses were applied to the human brainstem frequency-following response and cortical auditory evoked response recorded on the same trials. Lagged cross-correlation functions were computed, for each of 17 subjects, between single-trial data and templates consisting of the sinusoid stimulus waveform for the brainstem response and the subject's own smoothed averaged evoked response P2 component for the cortical response. Trials were considered in the analysis only if the maximum correlation-squared (r2) exceeded .5 (negatively correlated trials were thus included). Identical correlation coefficients may be based on signals with quite different amplitudes, but it is possible to assess amplitude by the nonnormalized covariance function. Next, an algorithm is applied in which each trial with negative covariance is matched to a trial with similar, but positive, covariance and these matched-trial pairs are deleted. When an evoked response signal is present in the data, the majority of trials positively correlate with the template. Thus, a residual of positively correlated trials remains after matched covariance trials are deleted. When these residual trials are averaged, the resulting brainstem and cortical responses show greatly enhanced amplitudes. This result supports the utility of this analysis technique in clarifying and assessing evoked response signals.

  20. Validity of selected physical activity questions in white Seventh-day Adventists and non-Adventists.

    PubMed

    Singh, P N; Tonstad, S; Abbey, D E; Fraser, G E

    1996-08-01

    The validity and reliability of selected physical activity questions were assessed in both Seventh-day Adventist (N = 131) and non-Adventist (N = 101) study groups. Vigorous activity questions similar to those used by others and new questions that measured moderate and light activities were included. Validation was external, comparing questionnaire data with treadmill exercise time, resting heart rate, and body mass index (kg.m-2), and internal, comparing data with other similar questions. Both Adventist and non-Adventist males showed significant age-adjusted correlations between treadmill time and a "Run-Walk-Jog Index" (R = 0.28, R = 0.48, respectively). These correlations increased substantially when restricting analysis to exercise speeds exceeding 3 mph (R = 0.39, R = 0.71, respectively). Frequency of sweating and a vigorous physical activity index also correlated significantly with treadmill time in males. Correlations were generally weaker in females. Moderate- and light-intensity questions were not correlated with physical fitness. Internal correlations R = 0.50-0.78) between the above three vigorous activity questions were significant in all groups, and correlations (R = 0.14-0.60) for light and moderate activity questions were also documented. Test-retest reliability coefficients were high for vigorous activity questions (R = 0.48-0.85) and for one set of moderate activity questions (R = 0.43-0.75). No important differences in validity and reliability were found between Adventist and non-Adventists, but the validity of vigorous activity measures was generally weaker in females.

  1. Development of multivariate NTCP models for radiation-induced hypothyroidism: a comparative analysis.

    PubMed

    Cella, Laura; Liuzzi, Raffaele; Conson, Manuel; D'Avino, Vittoria; Salvatore, Marco; Pacelli, Roberto

    2012-12-27

    Hypothyroidism is a frequent late side effect of radiation therapy of the cervical region. Purpose of this work is to develop multivariate normal tissue complication probability (NTCP) models for radiation-induced hypothyroidism (RHT) and to compare them with already existing NTCP models for RHT. Fifty-three patients treated with sequential chemo-radiotherapy for Hodgkin's lymphoma (HL) were retrospectively reviewed for RHT events. Clinical information along with thyroid gland dose distribution parameters were collected and their correlation to RHT was analyzed by Spearman's rank correlation coefficient (Rs). Multivariate logistic regression method using resampling methods (bootstrapping) was applied to select model order and parameters for NTCP modeling. Model performance was evaluated through the area under the receiver operating characteristic curve (AUC). Models were tested against external published data on RHT and compared with other published NTCP models. If we express the thyroid volume exceeding X Gy as a percentage (Vx(%)), a two-variable NTCP model including V30(%) and gender resulted to be the optimal predictive model for RHT (Rs = 0.615, p < 0.001. AUC = 0.87). Conversely, if absolute thyroid volume exceeding X Gy (Vx(cc)) was analyzed, an NTCP model based on 3 variables including V30(cc), thyroid gland volume and gender was selected as the most predictive model (Rs = 0.630, p < 0.001. AUC = 0.85). The three-variable model performs better when tested on an external cohort characterized by large inter-individuals variation in thyroid volumes (AUC = 0.914, 95% CI 0.760-0.984). A comparable performance was found between our model and that proposed in the literature based on thyroid gland mean dose and volume (p = 0.264). The absolute volume of thyroid gland exceeding 30 Gy in combination with thyroid gland volume and gender provide an NTCP model for RHT with improved prediction capability not only within our patient population but also in an external cohort.

  2. Cross-cultural Adaptation and Validation of the Medication Regimen Complexity Index Adapted to Spanish.

    PubMed

    Saez de la Fuente, Javier; Such Diaz, Ana; Cañamares-Orbis, Irene; Ramila, Estela; Izquierdo-Garcia, Elsa; Esteban, Concepcion; Escobar-Rodríguez, Ismael

    2016-11-01

    The most widely used validated instrument to assess the complexity of medication regimens is the Medication Regimen Complexity Index (MRCI). This study aimed to translate, adapt, and validate a reliable version of the MRCI adapted to Spanish (MRCI-E). The cross-cultural adaptation process consisted of an independent translation by 3 clinical pharmacists and a backtranslation by 2 native English speakers. A reliability analysis was conducted on 20 elderly randomly selected patients. Two clinical pharmacists calculated the MRCI-E from discharge treatments and 2 months later. For the validity analysis, the sample was augmented to 60 patients. Convergent validity was assessed by analyzing the correlation between the number of medications; discriminant validity was stratified by gender; and predictive validity was determined by analyzing the ability to predict readmission and mortality at 3 and 6 months. The MRCI-E retained the original structure of 3 sections. The reliability analysis demonstrated an excellent internal consistency (Cronbach's α=0.83), and the intraclass correlation coefficient exceeded 0.9 in all cases. The correlation coefficient with the number of medications was 0.883 ( P<0.001). No significant differences were found when stratified by gender (3.6; 95%CI=-2.9 to 10.2; P=0.27). Patients who were readmitted at 3 months had a higher MRCI-E score (10.7; 95%CI=4.4 to 17.2; P=0.001). The differences remained significant in patients readmitted at 6 months, but differences in mortality were not detected. The MRCI-E retains the reliability and validity of the original index and provides a suitable tool to assess the complexity of medication regimens in Spanish.

  3. Comparison of tibiofemoral joint space width measurements from standing CT and fixed flexion radiography.

    PubMed

    Segal, Neil A; Frick, Eric; Duryea, Jeffrey; Nevitt, Michael C; Niu, Jingbo; Torner, James C; Felson, David T; Anderson, Donald D

    2017-07-01

    The objective of this project was to determine the relationship between medial tibiofemoral joint space width measured on fixed-flexion radiographs and the three-dimensional joint space width distribution on low-dose, standing CT (SCT) imaging. At the 84-month visit of the Multicenter Osteoarthritis Study, 20 participants were recruited. A commercial SCT scanner for the foot and ankle was modified to image knees while standing. Medial tibiofemoral joint space width was assessed on radiographs at fixed locations from 15% to 30% of compartment width using validated software and on SCT by mapping the distances between three-dimensional subchondral bone surfaces. Individual joint space width values from radiographs were compared with three-dimensional joint space width values from corresponding sagittal plane locations using paired t-tests and correlation coefficients. For the four medial-most tibiofemoral locations, radiographic joint space width values exceeded the minimal joint space width on SCT by a mean of 2.0 mm and were approximately equal to the 61st percentile value of the joint space width distribution at each respective sagittal-plane location. Correlation coefficients at these locations were 0.91-0.97 and the offsets between joint space width values from radiographs and SCT measurements were consistent. There were greater offsets and variability in the offsets between modalities closer to the tibial spine. Joint space width measurements on fixed-flexion radiographs are highly correlated with three-dimensional joint space width from SCT. In addition to avoiding bony overlap obscuring the joint, a limitation of radiographs, the current study supports a role for SCT in the evaluation of tibiofemoral OA. © 2017 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 35:1388-1395, 2017. © 2017 Orthopaedic Research Society. Published by Wiley Periodicals, Inc.

  4. Validity and reliability of the Iranian version of the Pediatric Quality of Life Inventory™ 4.0 (PedsQL™) Generic Core Scales in children

    PubMed Central

    2012-01-01

    Background This study aimed to investigate the reliability and validity of the Iranian version of the Pediatric Quality of Life Inventory™ 4.0 (PedsQL™ 4.0) Generic Core Scales in children. Methods A standard forward and backward translation procedure was used to translate the US English version of the PedsQL™ 4.0 Generic Core Scales for children into the Iranian language (Persian). The Iranian version of the PedsQL™ 4.0 Generic Core Scales was completed by 503 healthy and 22 chronically ill children aged 8-12 years and their parents. The reliability was evaluated using internal consistency. Known-groups discriminant comparisons were made, and exploratory factor analysis (EFA) and confirmatory factor analysis (CFA) were conducted. Results The internal consistency, as measured by Cronbach's alpha coefficients, exceeded the minimum reliability standard of 0.70. All monotrait-multimethod correlations were higher than multitrait-multimethod correlations. The intraclass correlation coefficients (ICC) between the children self-report and parent proxy-reports showed moderate to high agreement. Exploratory factor analysis extracted six factors from the PedsQL™ 4.0 for both self and proxy reports, accounting for 47.9% and 54.8% of total variance, respectively. The results of the confirmatory factor analysis for 6-factor models for both self-report and proxy-report indicated acceptable fit for the proposed models. Regarding health status, as hypothesized from previous studies, healthy children reported significantly higher health-related quality of life than those with chronic illnesses. Conclusions The findings support the initial reliability and validity of the Iranian version of the PedsQL™ 4.0 as a generic instrument to measure health-related quality of life of children in Iran. PMID:22221765

  5. Validity and reliability of the Iranian version of the Pediatric Quality of Life Inventory™ 4.0 (PedsQL™) Generic Core Scales in children.

    PubMed

    Amiri, Parisa; Eslamian, Ghazaleh; Mirmiran, Parvin; Shiva, Niloofar; Jafarabadi, Mohammad Asghari; Azizi, Fereidoun

    2012-01-05

    This study aimed to investigate the reliability and validity of the Iranian version of the Pediatric Quality of Life Inventory™ 4.0 (PedsQL™ 4.0) Generic Core Scales in children. A standard forward and backward translation procedure was used to translate the US English version of the PedsQL™ 4.0 Generic Core Scales for children into the Iranian language (Persian). The Iranian version of the PedsQL™ 4.0 Generic Core Scales was completed by 503 healthy and 22 chronically ill children aged 8-12 years and their parents. The reliability was evaluated using internal consistency. Known-groups discriminant comparisons were made, and exploratory factor analysis (EFA) and confirmatory factor analysis (CFA) were conducted. The internal consistency, as measured by Cronbach's alpha coefficients, exceeded the minimum reliability standard of 0.70. All monotrait-multimethod correlations were higher than multitrait-multimethod correlations. The intraclass correlation coefficients (ICC) between the children self-report and parent proxy-reports showed moderate to high agreement. Exploratory factor analysis extracted six factors from the PedsQL™ 4.0 for both self and proxy reports, accounting for 47.9% and 54.8% of total variance, respectively. The results of the confirmatory factor analysis for 6-factor models for both self-report and proxy-report indicated acceptable fit for the proposed models. Regarding health status, as hypothesized from previous studies, healthy children reported significantly higher health-related quality of life than those with chronic illnesses. The findings support the initial reliability and validity of the Iranian version of the PedsQL™ 4.0 as a generic instrument to measure health-related quality of life of children in Iran.

  6. Correlation coefficient measurement of the mode-locked laser tones using four-wave mixing.

    PubMed

    Anthur, Aravind P; Panapakkam, Vivek; Vujicic, Vidak; Merghem, Kamel; Lelarge, Francois; Ramdane, Abderrahim; Barry, Liam P

    2016-06-01

    We use four-wave mixing to measure the correlation coefficient of comb tones in a quantum-dash mode-locked laser under passive and active locked regimes. We study the uncertainty in the measurement of the correlation coefficient of the proposed method.

  7. Challenge of assessing symptoms in seriously ill intensive care unit patients: can proxy reporters help?

    PubMed

    Puntillo, Kathleen A; Neuhaus, John; Arai, Shoshana; Paul, Steven M; Gropper, Michael A; Cohen, Neal H; Miaskowski, Christine

    2012-10-01

    Determine levels of agreement among intensive care unit patients and their family members, nurses, and physicians (proxies) regarding patients' symptoms and compare levels of mean intensity (i.e., the magnitude of a symptom sensation) and distress (i.e., the degree of emotionality that a symptom engenders) of symptoms among patients and proxy reporters. Prospective study of proxy reporters of symptoms in seriously ill patients. Two intensive care units in a tertiary medical center in the Western United States. Two hundred and forty-five intensive care unit patients, 243 family members, 103 nurses, and 92 physicians. None. On the basis of the magnitude of intraclass correlation coefficients, where coefficients from .35 to .78 are considered to be appropriately robust, correlation coefficients between patients' and family members' ratings met this criterion (≥.35) for intensity in six of ten symptoms. No intensity ratings between patients and nurses had intraclass correlation coefficients >.32. Three symptoms had intensity correlation coefficients of ≥.36 between patients' and physicians' ratings. Correlation coefficients between patients and family members were >.40 for five symptom-distress ratings. No symptoms had distress correlation coefficients of ≥.28 between patients' and nurses' ratings. Two symptoms had symptom-distress correlation coefficients between patients' and physicians' ratings at >.39. Family members, nurses, and physicians reported higher symptom-intensity scores than patients did for 80%, 60%, and 60% of the symptoms, respectively. Family members, nurses, and physicians reported higher symptom-distress scores than patients did for 90%, 70%, and 80% of the symptoms, respectively. Patient-family intraclass correlation coefficients were sufficiently close for us to consider using family members to help assess intensive care unit patients' symptoms. Relatively low intraclass correlation coefficients between intensive care unit clinicians' and patients' symptom ratings indicate that some proxy raters overestimate whereas others underestimate patients' symptoms. Proxy overestimation of patients' symptom scores warrants further study because this may influence decisions about treating patients' symptoms.

  8. A Novel Analysis Of The Connection Between Indian Monsoon Rainfall And Solar Activity

    NASA Astrophysics Data System (ADS)

    Bhattacharyya, S.; Narasimha, R.

    2005-12-01

    The existence of possible correlations between the solar cycle period as extracted from the yearly means of sunspot numbers and any periodicities that may be present in the Indian monsoon rainfall has been addressed using wavelet analysis. The wavelet transform coefficient maps of sunspot-number time series and those of the homogeneous Indian monsoon rainfall annual time series data reveal striking similarities, especially around the 11-year period. A novel method to analyse and quantify this similarity devising statistical schemes is suggested in this paper. The wavelet transform coefficient maxima at the 11-year period for the sunspot numbers and the monsoon rainfall have each been modelled as a point process in time and a statistical scheme for identifying a trend or dependence between the two processes has been devised. A regression analysis of parameters in these processes reveals a nearly linear trend with small but systematic deviations from the regressed line. Suitable function models for these deviations have been obtained through an unconstrained error minimisation scheme. These models provide an excellent fit to the time series of the given wavelet transform coefficient maxima obtained from actual data. Statistical significance tests on these deviations suggest with 99% confidence that the deviations are sample fluctuations obtained from normal distributions. In fact our earlier studies (see, Bhattacharyya and Narasimha, 2005, Geophys. Res. Lett., Vol. 32, No. 5) revealed that average rainfall is higher during periods of greater solar activity for all cases, at confidence levels varying from 75% to 99%, being 95% or greater in 3 out of 7 of them. Analysis using standard wavelet techniques reveals higher power in the 8--16 y band during the higher solar activity period, in 6 of the 7 rainfall time series, at confidence levels exceeding 99.99%. Furthermore, a comparison between the wavelet cross spectra of solar activity with rainfall and noise (including those simulating the rainfall spectrum and probability distribution) revealed that over the two test-periods respectively of high and low solar activity, the average cross power of the solar activity index with rainfall exceeds that with the noise at z-test confidence levels exceeding 99.99% over period-bands covering the 11.6 y sunspot cycle (see, Bhattacharyya and Narasimha, SORCE 2005 14-16th September, at Durango, Colorado USA). These results provide strong evidence for connections between Indian rainfall and solar activity. The present study reveals in addition the presence of subharmonics of the solar cycle period in the monsoon rainfall time series together with information on their phase relationships.

  9. Empirical correlations for axial dispersion coefficient and Peclet number in fixed-bed columns.

    PubMed

    Rastegar, Seyed Omid; Gu, Tingyue

    2017-03-24

    In this work, a new correlation for the axial dispersion coefficient was obtained using experimental data in the literature for axial dispersion in fixed-bed columns packed with particles. The Chung and Wen correlation, the De Ligny correlation are two popular empirical correlations. However, the former lacks the molecular diffusion term and the latter does not consider bed voidage. The new axial dispersion coefficient correlation in this work was based on additional experimental data in the literature by considering both molecular diffusion and bed voidage. It is more comprehensive and accurate. The Peclet number correlation from the new axial dispersion coefficient correlation on the average leads to 12% lower Peclet number values compared to the values from the Chung and Wen correlation, and in many cases much smaller than those from the De Ligny correlation. Copyright © 2017 Elsevier B.V. All rights reserved.

  10. Hydrodynamics of the Semi-Immersed Cylinder by Forced Oscillation Model Testing

    NASA Astrophysics Data System (ADS)

    Song, Chun-hui; Fu, Shi-xiao; Tang, Xiao-ying; Hu, Ke; Ma, Lei-xin; Ren, Tong-xin

    2018-03-01

    In this paper, the hydrodynamic coefficients of a horizontal semi-immersed cylinder in steady current and oscillatory flow combining with constant current are obtained via forced oscillation experiments in a towing tank. Three nondimensional parameters ( Re, KC and Fr) are introduced to investigate their effects on the hydrodynamic coefficients. The experimental results show that overtopping is evident and dominates when the Reynolds number exceeds 5×105 in the experiment. Under steady current condition, overtopping increases the drag coefficient significantly at high Reynolds numbers. Under oscillatory flow with constant current condition, the added mass coefficient can even reach a maximum value about 3.5 due to overtopping while the influence of overtopping on the drag coefficient is minor.

  11. Testing the Difference of Correlated Agreement Coefficients for Statistical Significance

    ERIC Educational Resources Information Center

    Gwet, Kilem L.

    2016-01-01

    This article addresses the problem of testing the difference between two correlated agreement coefficients for statistical significance. A number of authors have proposed methods for testing the difference between two correlated kappa coefficients, which require either the use of resampling methods or the use of advanced statistical modeling…

  12. Estimating Seven Coefficients of Pairwise Relatedness Using Population-Genomic Data

    PubMed Central

    Ackerman, Matthew S.; Johri, Parul; Spitze, Ken; Xu, Sen; Doak, Thomas G.; Young, Kimberly; Lynch, Michael

    2017-01-01

    Population structure can be described by genotypic-correlation coefficients between groups of individuals, the most basic of which are the pairwise relatedness coefficients between any two individuals. There are nine pairwise relatedness coefficients in the most general model, and we show that these can be reduced to seven coefficients for biallelic loci. Although all nine coefficients can be estimated from pedigrees, six coefficients have been beyond empirical reach. We provide a numerical optimization procedure that estimates all seven reduced coefficients from population-genomic data. Simulations show that the procedure is nearly unbiased, even at 3× coverage, and errors in five of the seven coefficients are statistically uncorrelated. The remaining two coefficients have a negative correlation of errors, but their sum provides an unbiased assessment of the overall correlation of heterozygosity between two individuals. Application of these new methods to four populations of the freshwater crustacean Daphnia pulex reveal the occurrence of half siblings in our samples, as well as a number of identical individuals that are likely obligately asexual clone mates. Statistically significant negative estimates of these pairwise relatedness coefficients, including inbreeding coefficients that were typically negative, underscore the difficulties that arise when interpreting genotypic correlations as estimations of the probability that alleles are identical by descent. PMID:28341647

  13. D2O self-broadening study in 2.5 μ

    NASA Astrophysics Data System (ADS)

    Lavrentieva, N.; Lugovskoi, A.; Sinitsa, L.; Sherbakov, A.; Svetlichny, O.

    2014-11-01

    The absorption spectra of the D2O monomer in 3600…4200 cm-1 were recorded using Fourier Transform spectrometer FS-125M at room temperature and pressure of 15 and 33 mbar with spectral resolution of 0.03 cm-1 using 2.5 cm long absorption cell. Strong unblended D2O lines lying on the wing of the H2O stretching band were used to determine the line broadening parameters. They were determined from the line profile by Program VxpProfile. The differences between fitted line profiles and experimental ones do not exceed 2%. Registered D2O lines belong to (011) - (000) and (110) - (000) bands of the second triad. Self-broadening coefficients vary from 0.27 cm-1/atm to 0.445 cm-1/atm and they exceed 3 times the D2O-N2 line broadening coefficients in the v3. Calculations of self-broadening coefficients of the D2O lines were performed using semiempirical method based on the impact theory of broadening and included the correction factors. The calculated results well agree with experimental data.

  14. Return period adjustment for runoff coefficients based on analysis in undeveloped Texas watersheds

    USGS Publications Warehouse

    Dhakal, Nirajan; Fang, Xing; Asquith, William H.; Cleveland, Theodore G.; Thompson, David B.

    2013-01-01

    The rational method for peak discharge (Qp) estimation was introduced in the 1880s. The runoff coefficient (C) is a key parameter for the rational method that has an implicit meaning of rate proportionality, and the C has been declared a function of the annual return period by various researchers. Rate-based runoff coefficients as a function of the return period, C(T), were determined for 36 undeveloped watersheds in Texas using peak discharge frequency from previously published regional regression equations and rainfall intensity frequency for return periods T of 2, 5, 10, 25, 50, and 100 years. The C(T) values and return period adjustments C(T)/C(T=10  year) determined in this study are most applicable to undeveloped watersheds. The return period adjustments determined for the Texas watersheds in this study and those extracted from prior studies of non-Texas data exceed values from well-known literature such as design manuals and textbooks. Most importantly, the return period adjustments exceed values currently recognized in Texas Department of Transportation design guidance when T>10  years.

  15. Attenuation of the Squared Canonical Correlation Coefficient under Varying Estimates of Score Reliability

    ERIC Educational Resources Information Center

    Wilson, Celia M.

    2010-01-01

    Research pertaining to the distortion of the squared canonical correlation coefficient has traditionally been limited to the effects of sampling error and associated correction formulas. The purpose of this study was to compare the degree of attenuation of the squared canonical correlation coefficient under varying conditions of score reliability.…

  16. Thin and Slow Smoke Detection by Using Frequency Image

    NASA Astrophysics Data System (ADS)

    Zheng, Guang; Oe, Shunitiro

    In this paper, a new method to detect thin and slow smoke for early fire alarm by using frequency image has been proposed. The correlation coefficient of the frequency image between the current stage and the initial stage are calculated, so are the gray image correlation coefficient of the color image. When the thin smoke close to transparent enters into the camera view, the correlation coefficient of the frequency image becomes small, while the gray image correlation coefficient of the color image hardly change and keep large. When something which is not transparent, like human beings, etc., enters into the camera view, the correlation coefficient of the frequency image becomes small, as well as that of color image. Based on the difference of correlation coefficient between frequency image and color image in different situations, the thin smoke can be detected. Also, considering the movement of the thin smoke, miss detection caused by the illustration change or noise can be avoided. Several experiments in different situations are carried out, and the experimental results show the effect of the proposed method.

  17. Statistical Study of Turbulence: Spectral Functions and Correlation Coefficients

    NASA Technical Reports Server (NTRS)

    Frenkiel, Francois N.

    1958-01-01

    In reading the publications on turbulence of different authors, one often runs the risk of confusing the various correlation coefficients and turbulence spectra. We have made a point of defining, by appropriate concepts, the differences which exist between these functions. Besides, we introduce in the symbols a few new characteristics of turbulence. In the first chapter, we study some relations between the correlation coefficients and the different turbulence spectra. Certain relations are given by means of demonstrations which could be called intuitive rather than mathematical. In this way we demonstrate that the correlation coefficients between the simultaneous turbulent velocities at two points are identical, whether studied in Lagrange's or in Euler's systems. We then consider new spectra of turbulence, obtained by study of the simultaneous velocities along a straight line of given direction. We determine some relations between these spectra and the correlation coefficients. Examining the relation between the spectrum of the turbulence measured at a fixed point and the longitudinal-correlation curve given by G. I. Taylor, we find that this equation is exact only when the coefficient is very small.

  18. [Electroencephalogram Feature Selection Based on Correlation Coefficient Analysis].

    PubMed

    Zhou, Jinzhi; Tang, Xiaofang

    2015-08-01

    In order to improve the accuracy of classification with small amount of motor imagery training data on the development of brain-computer interface (BCD systems, we proposed an analyzing method to automatically select the characteristic parameters based on correlation coefficient analysis. Throughout the five sample data of dataset IV a from 2005 BCI Competition, we utilized short-time Fourier transform (STFT) and correlation coefficient calculation to reduce the number of primitive electroencephalogram dimension, then introduced feature extraction based on common spatial pattern (CSP) and classified by linear discriminant analysis (LDA). Simulation results showed that the average rate of classification accuracy could be improved by using correlation coefficient feature selection method than those without using this algorithm. Comparing with support vector machine (SVM) optimization features algorithm, the correlation coefficient analysis can lead better selection parameters to improve the accuracy of classification.

  19. Quantifying the range of cross-correlated fluctuations using a q- L dependent AHXA coefficient

    NASA Astrophysics Data System (ADS)

    Wang, Fang; Wang, Lin; Chen, Yuming

    2018-03-01

    Recently, based on analogous height cross-correlation analysis (AHXA), a cross-correlation coefficient ρ×(L) has been proposed to quantify the levels of cross-correlation on different temporal scales for bivariate series. A limitation of this coefficient is that it cannot capture the full information of cross-correlations on amplitude of fluctuations. In fact, it only detects the cross-correlation at a specific order fluctuation, which might neglect some important information inherited from other order fluctuations. To overcome this disadvantage, in this work, based on the scaling of the qth order covariance and time delay L, we define a two-parameter dependent cross-correlation coefficient ρq(L) to detect and quantify the range and level of cross-correlations. This new version of ρq(L) coefficient leads to the formation of a ρq(L) surface, which not only is able to quantify the level of cross-correlations, but also allows us to identify the range of fluctuation amplitudes that are correlated in two given signals. Applications to the classical ARFIMA models and the binomial multifractal series illustrate the feasibility of this new coefficient ρq(L) . In addition, a statistical test is proposed to quantify the existence of cross-correlations between two given series. Applying our method to the real life empirical data from the 1999-2000 California electricity market, we find that the California power crisis in 2000 destroys the cross-correlation between the price and the load series but does not affect the correlation of the load series during and before the crisis.

  20. Quantifying colocalization by correlation: the Pearson correlation coefficient is superior to the Mander's overlap coefficient.

    PubMed

    Adler, Jeremy; Parmryd, Ingela

    2010-08-01

    The Pearson correlation coefficient (PCC) and the Mander's overlap coefficient (MOC) are used to quantify the degree of colocalization between fluorophores. The MOC was introduced to overcome perceived problems with the PCC. The two coefficients are mathematically similar, differing in the use of either the absolute intensities (MOC) or of the deviation from the mean (PCC). A range of correlated datasets, which extend to the limits of the PCC, only evoked a limited response from the MOC. The PCC is unaffected by changes to the offset while the MOC increases when the offset is positive. Both coefficients are independent of gain. The MOC is a confusing hybrid measurement, that combines correlation with a heavily weighted form of co-occurrence, favors high intensity combinations, downplays combinations in which either or both intensities are low and ignores blank pixels. The PCC only measures correlation. A surprising finding was that the addition of a second uncorrelated population can substantially increase the measured correlation, demonstrating the importance of excluding background pixels. Overall, since the MOC is unresponsive to substantial changes in the data and is hard to interpret, it is neither an alternative to nor a useful substitute for the PCC. The MOC is not suitable for making measurements of colocalization either by correlation or co-occurrence.

  1. Can Imaging Parameters Provide Information Regarding Histopathology in Head and Neck Squamous Cell Carcinoma? A Meta-Analysis.

    PubMed

    Surov, Alexey; Meyer, Hans Jonas; Wienke, Andreas

    2018-04-01

    Our purpose was to provide data regarding relationships between different imaging and histopathological parameters in HNSCC. MEDLINE library was screened for associations between different imaging parameters and histopathological features in HNSCC up to December 2017. Only papers containing correlation coefficients between different imaging parameters and histopathological findings were acquired for the analysis. Associations between 18 F-FDG positron emission tomography (PET) and KI 67 were reported in 8 studies (236 patients). The pooled correlation coefficient was 0.20 (95% CI = [-0.04; 0.44]). Furthermore, in 4 studies (64 patients), associations between 18 F-fluorothymidine PET and KI 67 were analyzed. The pooled correlation coefficient between SUV max and KI 67 was 0.28 (95% CI = [-0.06; 0.94]). In 2 studies (23 patients), relationships between KI 67 and dynamic contrast-enhanced magnetic resonance imaging were reported. The pooled correlation coefficient between K trans and KI 67 was -0.68 (95% CI = [-0.91; -0.44]). Two studies (31 patients) investigated correlation between apparent diffusion coefficient (ADC) and KI 67. The pooled correlation coefficient was -0.61 (95% CI = [-0.84; -0.38]). In 2 studies (117 patients), relationships between 18 F-FDG PET and p53 were analyzed. The pooled correlation coefficient was 0.0 (95% CI = [-0.87; 0.88]). There were 3 studies (48 patients) that investigated associations between ADC and tumor cell count in HNSCC. The pooled correlation coefficient was -0.53 (95% CI = [-0.74; -0.32]). Associations between 18 F-FDG PET and HIF-1α were investigated in 3 studies (72 patients). The pooled correlation coefficient was 0.44 (95% CI = [-0.20; 1.08]). ADC may predict cell count and proliferation activity, and SUV max may predict expression of HIF-1α in HNSCC. SUV max cannot be used as surrogate marker for expression of KI 67 and p53. Copyright © 2018 The Authors. Published by Elsevier Inc. All rights reserved.

  2. Measuring User Similarity Using Electric Circuit Analysis: Application to Collaborative Filtering

    PubMed Central

    Yang, Joonhyuk; Kim, Jinwook; Kim, Wonjoon; Kim, Young Hwan

    2012-01-01

    We propose a new technique of measuring user similarity in collaborative filtering using electric circuit analysis. Electric circuit analysis is used to measure the potential differences between nodes on an electric circuit. In this paper, by applying this method to transaction networks comprising users and items, i.e., user–item matrix, and by using the full information about the relationship structure of users in the perspective of item adoption, we overcome the limitations of one-to-one similarity calculation approach, such as the Pearson correlation, Tanimoto coefficient, and Hamming distance, in collaborative filtering. We found that electric circuit analysis can be successfully incorporated into recommender systems and has the potential to significantly enhance predictability, especially when combined with user-based collaborative filtering. We also propose four types of hybrid algorithms that combine the Pearson correlation method and electric circuit analysis. One of the algorithms exceeds the performance of the traditional collaborative filtering by 37.5% at most. This work opens new opportunities for interdisciplinary research between physics and computer science and the development of new recommendation systems PMID:23145095

  3. Measuring user similarity using electric circuit analysis: application to collaborative filtering.

    PubMed

    Yang, Joonhyuk; Kim, Jinwook; Kim, Wonjoon; Kim, Young Hwan

    2012-01-01

    We propose a new technique of measuring user similarity in collaborative filtering using electric circuit analysis. Electric circuit analysis is used to measure the potential differences between nodes on an electric circuit. In this paper, by applying this method to transaction networks comprising users and items, i.e., user-item matrix, and by using the full information about the relationship structure of users in the perspective of item adoption, we overcome the limitations of one-to-one similarity calculation approach, such as the Pearson correlation, Tanimoto coefficient, and Hamming distance, in collaborative filtering. We found that electric circuit analysis can be successfully incorporated into recommender systems and has the potential to significantly enhance predictability, especially when combined with user-based collaborative filtering. We also propose four types of hybrid algorithms that combine the Pearson correlation method and electric circuit analysis. One of the algorithms exceeds the performance of the traditional collaborative filtering by 37.5% at most. This work opens new opportunities for interdisciplinary research between physics and computer science and the development of new recommendation systems.

  4. Neurocognitive deficits and history of childhood abuse in schizophrenia spectrum disorders: associations with Cluster B personality traits.

    PubMed

    Lysaker, Paul H; Wickett, Amanda M; Lancaster, Rebecca S; Davis, Louanne W

    2004-05-01

    Cluster B personality traits have been detected in persons with schizophrenia, at a rate exceeding that of the general population. Unclear, however, is how to account for such high rates of Cluster B traits. Accordingly, this study explored the hypothesis that the presence of these traits may be linked to impairments in neurocognition, and childhood abuse history. To test this, we simultaneously obtained an assessment of Cluster B traits using the Millon Clinical Multiaxial Inventory III, along with measures of attention, verbal memory, affect recognition, executive function and childhood abuse history among 37 persons with schizophrenia spectrum disorders in a post acute phases of illness. Pearson correlation coefficients revealed that higher levels of histrionic and narcissistic traits were related to poorer neurocognition while higher levels of narcissistic traits were negatively correlated with childhood physical abuse. Higher levels of borderline traits were uniquely related to the report of childhood sexual abuse while higher levels of antisocial traits were related to higher levels of childhood physical abuse. Theoretical and clinical implications are discussed.

  5. Exploring Large-Scale Cross-Correlation for Teleseismic and Regional Seismic Event Characterization

    NASA Astrophysics Data System (ADS)

    Dodge, Doug; Walter, William; Myers, Steve; Ford, Sean; Harris, Dave; Ruppert, Stan; Buttler, Dave; Hauk, Terri

    2013-04-01

    The decrease in costs of both digital storage space and computation power invites new methods of seismic data processing. At Lawrence Livermore National Laboratory(LLNL) we operate a growing research database of seismic events and waveforms for nuclear explosion monitoring and other applications. Currently the LLNL database contains several million events associated with tens of millions of waveforms at thousands of stations. We are making use of this database to explore the power of seismic waveform correlation to quantify signal similarities, to discover new events not in catalogs, and to more accurately locate events and identify source types. Building on the very efficient correlation methodologies of Harris and Dodge (2011) we computed the waveform correlation for event pairs in the LLNL database in two ways. First we performed entire waveform cross-correlation over seven distinct frequency bands. The correlation coefficient exceeds 0.6 for more than 40 million waveform pairs for several hundred thousand events at more than a thousand stations. These correlations reveal clusters of mining events and aftershock sequences, which can be used to readily identify and locate events. Second we determine relative pick times by correlating signals in time windows for distinct seismic phases. These correlated picks are then used to perform very high accuracy event relocations. We are examining the percentage of events that correlate as a function of magnitude and observing station distance in selected high seismicity regions. Combining these empirical results and those using synthetic data, we are working to quantify relationships between correlation and event pair separation (in epicenter and depth) as well as mechanism differences. Our exploration of these techniques on a large seismic database is in process and we will report on our findings in more detail at the meeting.

  6. Exploring Large-Scale Cross-Correlation for Teleseismic and Regional Seismic Event Characterization

    NASA Astrophysics Data System (ADS)

    Dodge, D.; Walter, W. R.; Myers, S. C.; Ford, S. R.; Harris, D.; Ruppert, S.; Buttler, D.; Hauk, T. F.

    2012-12-01

    The decrease in costs of both digital storage space and computation power invites new methods of seismic data processing. At Lawrence Livermore National Laboratory (LLNL) we operate a growing research database of seismic events and waveforms for nuclear explosion monitoring and other applications. Currently the LLNL database contains several million events associated with tens of millions of waveforms at thousands of stations. We are making use of this database to explore the power of seismic waveform correlation to quantify signal similarities, to discover new events not in catalogs, and to more accurately locate events and identify source types. Building on the very efficient correlation methodologies of Harris and Dodge (2011) we computed the waveform correlation for event pairs in the LLNL database in two ways. First we performed entire waveform cross-correlation over seven distinct frequency bands. The correlation coefficient exceeds 0.6 for more than 40 million waveform pairs for several hundred thousand events at more than a thousand stations. These correlations reveal clusters of mining events and aftershock sequences, which can be used to readily identify and locate events. Second we determine relative pick times by correlating signals in time windows for distinct seismic phases. These correlated picks are then used to perform very high accuracy event relocations. We are examining the percentage of events that correlate as a function of magnitude and observing station distance in selected high seismicity regions. Combining these empirical results and those using synthetic data, we are working to quantify relationships between correlation and event pair separation (in epicenter and depth) as well as mechanism differences. Our exploration of these techniques on a large seismic database is in process and we will report on our findings in more detail at the meeting.

  7. Lower extremity kinematics during walking and elliptical training in individuals with and without traumatic brain injury.

    PubMed

    Buster, Thad; Burnfield, Judith; Taylor, Adam P; Stergiou, Nicholas

    2013-12-01

    Elliptical training may be an option for practicing walking-like activity for individuals with traumatic brain injuries (TBI). Understanding similarities and differences between participants with TBI and neurologically healthy individuals during elliptical trainer use and walking may help guide clinical applications incorporating elliptical trainers. Ten participants with TBI and a comparison group of 10 neurologically healthy participants underwent 2 familiarization sessions and 1 data collection session. Kinematic data were collected as participants walked on a treadmill or on an elliptical trainer. Gait-related measures, including coefficient of multiple correlations (a measure of similarity between ensemble joint movement profiles; coefficient of multiple correlations [CMCs]), critical event joint angles, variability of peak critical event joint angles (standard deviations [SDs]) of peak critical event joint angles, and maximum Lyapunov exponents (a measure of the organization of the variability [LyEs]) were compared between groups and conditions. Coefficient of multiple correlations values comparing the similarity in ensemble motion profiles between the TBI and comparison participants exceeded 0.85 for the hip, knee, and ankle joints. The only critical event joint angle that differed significantly between participants with TBI and comparison participants was the ankle during terminal stance. Variability was higher for the TBI group (6 of 11 comparisons significant) compared with comparison participants. Hip and knee joint movement patterns of both participants with TBI and comparison participants on the elliptical trainer were similar to walking (CMCs ≥ 0.87). Variability was higher during elliptical trainer usage compared with walking (5 of 11 comparisons significant). Hip LyEs were higher during treadmill walking. Ankle LyEs were greater during elliptical trainer usage. Movement patterns of participants with TBI were similar to, but more variable than, those of comparison participants while using both the treadmill and the elliptical trainer. If incorporation of complex movements similar to walking is a goal of rehabilitation, elliptical training is a reasonable alternative to treadmill-based training.Video Abstract available (see Video, Supplemental Digital Content 1, http://links.lww.com/JNPT/A65) for more insights from the authors.

  8. Assessment of exposure to oak wood dust using gallic acid as a chemical marker.

    PubMed

    Carrieri, Mariella; Scapellato, Maria Luisa; Salamon, Fabiola; Gori, Giampaolo; Trevisan, Andrea; Bartolucci, Giovanni Battista

    2016-01-01

    The American Conference of Governmental Industrial Hygienists (ACGIH) has classified oak dust as a human carcinogen (A1), based on increased sinus and nasal cancer rates among exposed workers. The aims of this study were to investigate the use of gallic acid (GA) as a chemical marker of occupational exposure to oak dusts, to develop a high-performance liquid chromatography-diode array detector method to quantify GA and to apply the method in the analysis of oak dust samples collected in several factories. A high-performance liquid chromatography method was developed to detect GA in oak wood dust. The method was tested in the field, and GA was extracted from inhalable oak wood dust collected using the Institute of Occupational Medicine inhalable dust sampler in the air of five woodworking plants where only oak wood is used. A total of 57 samples with dust concentrations in the range of 0.27-11.14 mg/m(3) were collected. Five of these samples exceeded the Italian threshold limit value of 5 mg/m(3), and 30 samples exceeded the ACGIH TLV of 1 mg/m(3). The GA concentrations were in the range 0.02-4.18 µg/m(3). The total oak dust sampled was correlated with the GA content with a correlation coefficient (r) of 0.95. The GA in the tannic extracts of oak wood may be considered a good marker for this type of wood, and its concentration in wood dust sampled in the work environment is useful in assessing the true exposure to carcinogenic oak dust.

  9. A novel coefficient for detecting and quantifying asymmetry of California electricity market based on asymmetric detrended cross-correlation analysis.

    PubMed

    Wang, Fang

    2016-06-01

    In order to detect and quantify asymmetry of two time series, a novel cross-correlation coefficient is proposed based on recent asymmetric detrended cross-correlation analysis (A-DXA), which we called A-DXA coefficient. The A-DXA coefficient, as an important extension of DXA coefficient ρDXA, contains two directional asymmetric cross-correlated indexes, describing upwards and downwards asymmetric cross-correlations, respectively. By using the information of directional covariance function of two time series and directional variance function of each series itself instead of power-law between the covariance function and time scale, the proposed A-DXA coefficient can well detect asymmetry between the two series no matter whether the cross-correlation is significant or not. By means of the proposed A-DXA coefficient conducted over the asymmetry for California electricity market, we found that the asymmetry between the prices and loads is not significant for daily average data in 1999 yr market (before electricity crisis) but extremely significant for those in 2000 yr market (during the crisis). To further uncover the difference of asymmetry between the years 1999 and 2000, a modified H statistic (MH) and ΔMH statistic are proposed. One of the present contributions is that the high MH values calculated for hourly data exist in majority months in 2000 market. Another important conclusion is that the cross-correlation with downwards dominates over the whole 1999 yr in contrast to the cross-correlation with upwards dominates over the 2000 yr.

  10. Detecting PM2.5's Correlations between Neighboring Cities Using a Time-Lagged Cross-Correlation Coefficient.

    PubMed

    Wang, Fang; Wang, Lin; Chen, Yuming

    2017-08-31

    In order to investigate the time-dependent cross-correlations of fine particulate (PM2.5) series among neighboring cities in Northern China, in this paper, we propose a new cross-correlation coefficient, the time-lagged q-L dependent height crosscorrelation coefficient (denoted by p q (τ, L)), which incorporates the time-lag factor and the fluctuation amplitude information into the analogous height cross-correlation analysis coefficient. Numerical tests are performed to illustrate that the newly proposed coefficient ρ q (τ, L) can be used to detect cross-correlations between two series with time lags and to identify different range of fluctuations at which two series possess cross-correlations. Applying the new coefficient to analyze the time-dependent cross-correlations of PM2.5 series between Beijing and the three neighboring cities of Tianjin, Zhangjiakou, and Baoding, we find that time lags between the PM2.5 series with larger fluctuations are longer than those between PM2.5 series withsmaller fluctuations. Our analysis also shows that cross-correlations between the PM2.5 series of two neighboring cities are significant and the time lags between two PM2.5 series of neighboring cities are significantly non-zero. These findings providenew scientific support on the view that air pollution in neighboring cities can affect one another not simultaneously but with a time lag.

  11. Limits of the memory coefficient in measuring correlated bursts

    NASA Astrophysics Data System (ADS)

    Jo, Hang-Hyun; Hiraoka, Takayuki

    2018-03-01

    Temporal inhomogeneities in event sequences of natural and social phenomena have been characterized in terms of interevent times and correlations between interevent times. The inhomogeneities of interevent times have been extensively studied, while the correlations between interevent times, often called correlated bursts, are far from being fully understood. For measuring the correlated bursts, two relevant approaches were suggested, i.e., memory coefficient and burst size distribution. Here a burst size denotes the number of events in a bursty train detected for a given time window. Empirical analyses have revealed that the larger memory coefficient tends to be associated with the heavier tail of the burst size distribution. In particular, empirical findings in human activities appear inconsistent, such that the memory coefficient is close to 0, while burst size distributions follow a power law. In order to comprehend these observations, by assuming the conditional independence between consecutive interevent times, we derive the analytical form of the memory coefficient as a function of parameters describing interevent time and burst size distributions. Our analytical result can explain the general tendency of the larger memory coefficient being associated with the heavier tail of burst size distribution. We also find that the apparently inconsistent observations in human activities are compatible with each other, indicating that the memory coefficient has limits to measure the correlated bursts.

  12. Exceptional sensitivity of metal-aryl bond energies to ortho-fluorine substituents: influence of the metal, the coordination sphere, and the spectator ligands on M-C/H-C bond energy correlations.

    PubMed

    Clot, Eric; Mégret, Claire; Eisenstein, Odile; Perutz, Robin N

    2009-06-10

    DFT calculations are reported of the energetics of C-H oxidative addition of benzene and fluorinated benzenes, Ar(F)H (Ar(F) = C(6)F(n)H(5-n), n = 0-5) at ZrCp(2) (Cp = eta(5)-C(5)H(5)), TaCp(2)H, TaCp(2)Cl, WCp(2), ReCp(CO)(2), ReCp(CO)(PH(3)), ReCp(PH(3))(2), RhCp(PH(3)), RhCp(CO), IrCp(PH(3)), IrCp(CO), Ni(H(2)PCH(2)CH(2)PH(2)), Pt(H(2)PCH(2)CH(2)PH(2)). The change in M-C bond energy of the products fits a linear function of the number of fluorine substituents, with different coefficients corresponding to ortho-, meta-, and para-fluorine. The values of the ortho-coefficient range from 20 to 32 kJ mol(-1), greatly exceeding the values for the meta- and para-coefficients (2.0-4.5 kJ mol(-1)). Similarly, the H-C bond energies of Ar(F)H yield ortho- and para-coefficients of 10.4 and 3.4 kJ mol(-1), respectively, and a negligible meta-coefficient. These results indicate a large increase in the M-C bond energy with ortho-fluorine substitution on the aryl ring. Plots of D(M-C) vs D(H-C) yield slopes R(M-C/H-C) that vary from 1.93 to 3.05 with metal fragment, all in excess of values of 1.1-1.3 reported with other hydrocarbyl groups. Replacement of PH(3) by CO decreases R(M-C/H-C) significantly. For a given ligand set and metals in the same group of the periodic table, the value of R(M-C/H-C) does not increase with the strength of the M-C bond. Calculations of the charge on the aryl ring show that variations in ionicity of the M-C bonds correlate with variations in M-C bond energy. This strengthening of metal-aryl bonds accounts for numerous experimental results that indicate a preference for ortho-fluorine substituents.

  13. Correlation Coefficients: Appropriate Use and Interpretation.

    PubMed

    Schober, Patrick; Boer, Christa; Schwarte, Lothar A

    2018-05-01

    Correlation in the broadest sense is a measure of an association between variables. In correlated data, the change in the magnitude of 1 variable is associated with a change in the magnitude of another variable, either in the same (positive correlation) or in the opposite (negative correlation) direction. Most often, the term correlation is used in the context of a linear relationship between 2 continuous variables and expressed as Pearson product-moment correlation. The Pearson correlation coefficient is typically used for jointly normally distributed data (data that follow a bivariate normal distribution). For nonnormally distributed continuous data, for ordinal data, or for data with relevant outliers, a Spearman rank correlation can be used as a measure of a monotonic association. Both correlation coefficients are scaled such that they range from -1 to +1, where 0 indicates that there is no linear or monotonic association, and the relationship gets stronger and ultimately approaches a straight line (Pearson correlation) or a constantly increasing or decreasing curve (Spearman correlation) as the coefficient approaches an absolute value of 1. Hypothesis tests and confidence intervals can be used to address the statistical significance of the results and to estimate the strength of the relationship in the population from which the data were sampled. The aim of this tutorial is to guide researchers and clinicians in the appropriate use and interpretation of correlation coefficients.

  14. A study of correlations between crude oil spot and futures markets: A rolling sample test

    NASA Astrophysics Data System (ADS)

    Liu, Li; Wan, Jieqiu

    2011-10-01

    In this article, we investigate the asymmetries of exceedance correlations and cross-correlations between West Texas Intermediate (WTI) spot and futures markets. First, employing the test statistic proposed by Hong et al. [Asymmetries in stock returns: statistical tests and economic evaluation, Review of Financial Studies 20 (2007) 1547-1581], we find that the exceedance correlations were overall symmetric. However, the results from rolling windows show that some occasional events could induce the significant asymmetries of the exceedance correlations. Second, employing the test statistic proposed by Podobnik et al. [Quantifying cross-correlations using local and global detrending approaches, European Physics Journal B 71 (2009) 243-250], we find that the cross-correlations were significant even for large lagged orders. Using the detrended cross-correlation analysis proposed by Podobnik and Stanley [Detrended cross-correlation analysis: a new method for analyzing two nonstationary time series, Physics Review Letters 100 (2008) 084102], we find that the cross-correlations were weakly persistent and were stronger between spot and futures contract with larger maturity. Our results from rolling sample test also show the apparent effects of the exogenous events. Additionally, we have some relevant discussions on the obtained evidence.

  15. Occurrence of selected radionuclides in ground water used for drinking water in the United States; a reconnaissance survey, 1998

    USGS Publications Warehouse

    Focazio, Michael J.; Szabo, Zoltan; Kraemer, Thomas F.; Mullin, Ann H.; Barringer, Thomas H.; dePaul, Vincent T.

    2001-01-01

    The U.S. Geological Survey, in collaboration with the U.S. Environmental Protection Agency, the American Water Works Association, and the American Water Works Service Company, completed a targeted national reconnaissance survey of selected radionuclides in public ground-water supplies. Radionuclides analyzed included radium-224 (Ra-224), radium-226 (Ra-226), radium-228 (Ra-228), polonium-210 (Po-210) and lead-210 (Pb-210).This U.S. Geological Survey reconnaissance survey focused intentionally on areas with known or suspected elevated concentrations of radium in ground water to determine if Ra-224 was also present in the areas where other isotopes of radium had previously been detected and to determine the co-occurrence characteristics of the three radium isotopes (Ra-224, Ra-226, and Ra-228) in those areas. Ninety-nine raw-water samples (before water treatment) were collected once over a 6-month period in 1998 and 1999 from wells (94 of which are used for public drinking water) in 27 States and 8 physiographic provinces. Twenty-one of the 99 samples exceeded the current U.S. Environmental Protection Agency drinking-water maximum contaminant level of 5 picocuries per liter (pCi/L) for combined radium (Ra-226 + Ra-228). Concentrations of Ra-224 were reported to exceed 1 pCi/L in 30 percent of the samples collected, with a maximum concentration of 73.6 pCi/L measured in water from a nontransient, noncommunity, public-supply well in Maryland. Radium-224 concentrations generally were higher than those of the other isotopes of radium. About 5 percent of the samples contained concentrations of Ra-224 greater than 10 pCi/L, whereas only 2 percent exceeded 10 pCi/L for either Ra-226 or Ra-228. Concentrations of Ra-226 greater than 1 pCi/L were reported in 33 percent of the samples, with a maximum concentration of 16.9 pCi/L measured in water from a public-supply well in Iowa. Concentrations of Ra-228 greater than 1 pCi/L were reported in 22 samples, with a maximum concentration of 72.3 pCi/L measured in water from a non-transient, noncommunity, public-supply well in Maryland.Radium-224, which is a decay product of Ra-228 in the Th-232 decay series, was significantly correlated with Ra-228 (Spearman?s rank correlation coefficient ?r? equals 0.82) and to a lesser degree with Ra-226 (r equals 0.69), which is an isotope in the U-238 decay series. The rank correlation coefficient between Ra-226 and Ra-228 was 0.63. The high correlation between Ra-224 and Ra-228 concentrations and the corresponding isotopic ratios of the two (about 1:1 in 90 percent of the samples) indicates that the two radionuclides occur in approximately equal concentrations in most ground water sampled. Thus, Ra-228 can be considered as a reasonable proxy indicator for the occurrence of Ra-224 in ground water.The maximum concentration of Po-210 was 4.85 pCi/L and exceeded 1 pCi/L in only two samples. The maximum concentration of Pb-210 was 4.14 pCi/L, and about 10 percent of the samples exceeded 1 pCi/L. Areas with known, or suspected, elevated concentrations of polonium and lead were not targeted in this survey.Three major implications are drawn for future radionuclide monitoring on the basis of this information: (1) grossalpha particle analyses of ground water should be done within about 48?72 hours after collection to determine the presence of the short-lived, alpha-particle emitting isotopes, such as Ra-224, which was detected in elevated concentrations in many of the samples collected for this survey; (2) the isotope ratios of Ra-224 to Ra-228 in ground water are variable on a national scale, but the two radioisotopes generally occur in ratios near 1:1, therefore, the more commonly measured Ra-228 can be used as an indicator of Ra-224 occurrence for some general purposes other than compliance; and (3) the isotopic ratios of Ra-226 to Ra-228 were less than 3:2 in many samples. These ratios corroborate results of previous studies that have shown the presence of Ra-228

  16. Correlates of anxiety and depression among patients with type 2 diabetes mellitus.

    PubMed

    Balhara, Yatan Pal Singh; Sagar, Rajesh

    2011-07-01

    Research has established the relation between diabetes and depression. Both diabetes and anxiety/depression are independently associated with increased morbidity and mortality. The present study aims at assessing the prevalence of anxiety/depression among outpatients receiving treatment for type 2 diabetes. The study was conducted in the endocrinology outpatient department of an urban tertiary care center. The instruments used included a semi-structured questionnaire, HbA1c levels, fasting blood glucose and postprandial blood glucose, Brief Patient Health Questionnaire, and Hospital Anxiety and Depression Scale (HADS). Analysis was carried out using the SPSS version 16.0. Pearson's correlation coefficient was calculated to find out the correlations. ANOVA was carried out for the in between group comparisons. There was a significant correlation between the HADS-Anxiety scale and Body Mass Index (BMI) with a correlation coefficient of 0.34 (P = 0.008). Also, a significant correlation existed between HADS-Depression scale and BMI (correlation coefficient, 0.36; P = 0.004). Significant correlation were observed between the duration of daily physical exercise and HADS-Anxiety (coefficient of correlation, -0.25; P = 0.04) scores. HADS-Anxiety scores were found to be related to HbA1c levels (correlation-coefficient, 0.41; P = 0.03) and postprandial blood glucose levels (correlation-coefficient, 0.51; P = 0.02). Monitoring of biochemical parameters like HbA1c and postprandial blood glucose levels and BMI could be a guide to development of anxiety in these patients. Also, physical exercise seems to have a protective effect on anxiety in those with type 2 diabetes mellitus.

  17. Relationship between surface and free tropospheric ozone in the Western U.S.

    PubMed

    Jaffe, Dan

    2011-01-15

    Ozone is an important air pollutant that affects lung function. In the U.S., the EPA has reduced the allowable O(3) concentrations several times over the last few decades. This puts greater emphasis on understanding the interannual variability and the contributions to surface O(3) from all sources. We have examined O(3) data from 11 rural CASTNET sites in the western US for the period 1995-2009. The 11 surface sites show a similar seasonal cycle and generally a good correlation in the deseasonalized monthly means, indicating that there are large scale influences on O(3) that operate across the entire western US. These sites also show a good correlation between site elevation and annual mean O(3), indicating a significant contribution from the free troposphere. We examined the number of exceedance days for each site, defined as a day when the Maximum Daily 8-h Average (MDA8) exceeds a threshold value. Over this time period, more than half of these sites exceeded an MDA8 threshold of 70 ppbv at least 4 times per year, and all sites exceeded a threshold value of 65 ppbv at least 4 times per year. The transition to lower threshold values increases substantially the number of exceedance days, especially during spring, reflecting the fact that background O(3) peaks during spring. We next examined the correlation between surface O(3) and free tropospheric O(3) in the same region, as measured by routine balloon launches from Boulder, CO. Using ozone measured by the balloon sensor in the range of 3-6 km above sea level we find statistically significant correlations between surface and free tropospheric O(3) in spring and summer months using both monthly means, daily MDA8 values, and the number of surface exceedance days. We suggest that during spring this correlation reflects variations in the flux of O(3) transport from the free troposphere to the surface. In summer, free tropospheric and surface concentrations of O(3) and the number of exceedance days are all significantly correlated with emissions from biomass burning in the western US. This indicates that wildfires significantly increase the number of exceedance days across the western U.S.

  18. Prediction of friction coefficients for gases

    NASA Technical Reports Server (NTRS)

    Taylor, M. F.

    1969-01-01

    Empirical relations are used for correlating laminar and turbulent friction coefficients for gases, with large variations in the physical properties, flowing through smooth tubes. These relations have been used to correlate friction coefficients for hydrogen, helium, nitrogen, carbon dioxide and air.

  19. QSPR modeling of octanol/water partition coefficient of antineoplastic agents by balance of correlations.

    PubMed

    Toropov, Andrey A; Toropova, Alla P; Raska, Ivan; Benfenati, Emilio

    2010-04-01

    Three different splits into the subtraining set (n = 22), the set of calibration (n = 21), and the test set (n = 12) of 55 antineoplastic agents have been examined. By the correlation balance of SMILES-based optimal descriptors quite satisfactory models for the octanol/water partition coefficient have been obtained on all three splits. The correlation balance is the optimization of a one-variable model with a target function that provides both the maximal values of the correlation coefficient for the subtraining and calibration set and the minimum of the difference between the above-mentioned correlation coefficients. Thus, the calibration set is a preliminary test set. Copyright (c) 2009 Elsevier Masson SAS. All rights reserved.

  20. The Robustness of Designs for Trials with Nested Data against Incorrect Initial Intracluster Correlation Coefficient Estimates

    ERIC Educational Resources Information Center

    Korendijk, Elly J. H.; Moerbeek, Mirjam; Maas, Cora J. M.

    2010-01-01

    In the case of trials with nested data, the optimal allocation of units depends on the budget, the costs, and the intracluster correlation coefficient. In general, the intracluster correlation coefficient is unknown in advance and an initial guess has to be made based on published values or subject matter knowledge. This initial estimate is likely…

  1. Dynamics analysis of SIR epidemic model with correlation coefficients and clustering coefficient in networks.

    PubMed

    Zhang, Juping; Yang, Chan; Jin, Zhen; Li, Jia

    2018-07-14

    In this paper, the correlation coefficients between nodes in states are used as dynamic variables, and we construct SIR epidemic dynamic models with correlation coefficients by using the pair approximation method in static networks and dynamic networks, respectively. Considering the clustering coefficient of the network, we analytically investigate the existence and the local asymptotic stability of each equilibrium of these models and derive threshold values for the prevalence of diseases. Additionally, we obtain two equivalent epidemic thresholds in dynamic networks, which are compared with the results of the mean field equations. Copyright © 2018 Elsevier Ltd. All rights reserved.

  2. A novel coefficient for detecting and quantifying asymmetry of California electricity market based on asymmetric detrended cross-correlation analysis

    NASA Astrophysics Data System (ADS)

    Wang, Fang

    2016-06-01

    In order to detect and quantify asymmetry of two time series, a novel cross-correlation coefficient is proposed based on recent asymmetric detrended cross-correlation analysis (A-DXA), which we called A-DXA coefficient. The A-DXA coefficient, as an important extension of DXA coefficient ρ D X A , contains two directional asymmetric cross-correlated indexes, describing upwards and downwards asymmetric cross-correlations, respectively. By using the information of directional covariance function of two time series and directional variance function of each series itself instead of power-law between the covariance function and time scale, the proposed A-DXA coefficient can well detect asymmetry between the two series no matter whether the cross-correlation is significant or not. By means of the proposed A-DXA coefficient conducted over the asymmetry for California electricity market, we found that the asymmetry between the prices and loads is not significant for daily average data in 1999 yr market (before electricity crisis) but extremely significant for those in 2000 yr market (during the crisis). To further uncover the difference of asymmetry between the years 1999 and 2000, a modified H statistic (MH) and ΔMH statistic are proposed. One of the present contributions is that the high MH values calculated for hourly data exist in majority months in 2000 market. Another important conclusion is that the cross-correlation with downwards dominates over the whole 1999 yr in contrast to the cross-correlation with upwards dominates over the 2000 yr.

  3. Evaluation of the Correlation Coefficient of Polyethylene Glycol Treated and Direct Prolactin Results and Comparability with Different Assay System Results.

    PubMed

    Pal, Shyamali

    2017-12-01

    The presence of Macro prolactin is a significant cause of elevated prolactin resulting in misdiagnosis in all automated systems. Poly ethylene glycol (PEG) pretreatment is the preventive process but such process includes the probability of loss of a fraction of bioactive prolactin. Surprisingly, PEG treated EQAS & IQAS samples in Cobas e 411 are found out to be correlating with direct results of at least 3 immunoassay systems and treated and untreated Cobas e 411 results are comparable by a correlation coefficient. Comparison of EQAS, IQAS and patient samples were done to find out the trueness of such correlation factor. Study with patient's results have established the correlation coefficient is valid for very small concentration of prolactin also. EQAS, IQAS and 150 patient samples were treated with PEG and prolactin results of treated and untreated samples obtained from Roche Cobas e 411. 25 patient's results (treated) were compared with direct results in Advia Centaur, Architect I & Access2 systems. Correlation coefficient was obtained from trend line of the treated and untreated results. Two tailed p-value obtained from regression coefficient(r) and sample size. The correlation coefficient is in the range (0.761-0.771). Reverse correlation range is (1.289-1.301). r value of two sets of calculated results were 0.995. Two tailed p- value is zero approving dismissal of null hypothesis. The z-score of EQAS does not always assure authenticity of resultsPEG precipitation is correlated by the factor 0.761 even in very small concentrationsAbbreviationsGFCgel filtration chromatographyPEGpolyethylene glycolEQASexternal quality assurance systemM-PRLmacro prolactinPRLprolactinECLIAelectro-chemiluminescence immunoassayCLIAclinical laboratory improvement amendmentsIQASinternal quality assurance systemrregression coefficient.

  4. Intra-rater and inter-rater reliability of ultrasonographic measurements of acromion-greater tuberosity distance in patients with post-stroke hemiplegia.

    PubMed

    Kumar, Praveen; Cruziah, Reynold; Bradley, Michael; Gray, Selena; Swinkels, Annette

    2016-06-01

    Glenohumeral subluxation (GHS) is reported in up to 81% of patients with stroke. Ultrasonographic measurements of GHS by measuring the acromion-greater tuberosity (AGT) have been found to be reliable for experienced raters. The primary aim was to assess the intra-rater reliability of measurements of AGT distance in people with stroke following a short course of rater training. A secondary aim was to compare the inter-rater reliability of these measurements between novice and experienced raters. Patients with stroke (n = 16; 5 men, 11 women; 74 ± 10 years) with 1-sided weakness who gave informed consent were recruited. Ultrasonographic measurements were recorded at the bedside by two physiotherapists with patients seated upright in a hospital chair. Reliability was assessed by intra-class correlation coefficients (ICCs) and the standard error of measurements (SEM). Minimum detectable change (MDC90) scores were used to estimate the magnitude of change that is likely to exceed measurement error. Mean ± SD AGT distances on the affected and unaffected sides for rater 1 were 2.2 ± 0.7 and 1.7 ± 0.4 cm, respectively. Corresponding values for rater 2 were 2.5 ± 0.6 and 2.0 ± 0.4 cm. Intra-class correlation coefficient values for the affected and unaffected shoulders for rater 1 were 0.96 and 0.91, respectively. Corresponding values for rater 2 were 0.95 and 0.90.SEM and MDC90 for both affected and unaffected shoulders were ≤ 0.2 cm. Inter-rater reliability coefficients were 0.86 (affected) and 0.76 (unaffected) shoulders. Ultrasonographic measurement of AGT distance demonstrates excellent intra-rater reliability for a novice rater. Inter-rater reliability of ultrasonographic measurement of AGT also demonstrates good reliability between novice and experienced raters.

  5. Method of estimating flood-frequency parameters for streams in Idaho

    USGS Publications Warehouse

    Kjelstrom, L.C.; Moffatt, R.L.

    1981-01-01

    Skew coefficients for the log-Pearson type III distribution are generalized on the basis of some similarity of floods in the Snake River basin and other parts of Idaho. Generalized skew coefficients aid in shaping flood-frequency curves because skew coefficients computed from gaging stations having relatively short periods of peak flow records can be unreliable. Generalized skew coefficients can be obtained for a gaging station from one of three maps in this report. The map to be used depends on whether (1) snowmelt floods are domiant (generally when more than 20 percent of the drainage area is above 6,000 feet altitude), (2) rainstorm floods are dominant (generally when the mean altitude is less than 3,000 feet), or (3) either snowmelt or rainstorm floods can be the annual miximum discharge. For the latter case, frequency curves constructed using separate arrays of each type of runoff can be combined into one curve, which, for some stations, is significantly different than the frequency curve constructed using only annual maximum discharges. For 269 gaging stations, flood-frequency curves that include the generalized skew coefficients in the computation of the log-Pearson type III equation tend to fit the data better than previous analyses. Frequency curves for ungaged sites can be derived by estimating three statistics of the log-Pearson type III distribution. The mean and standard deviation of logarithms of annual maximum discharges are estimated by regression equations that use basin characteristics as independent variables. Skew coefficient estimates are the generalized skews. The log-Pearson type III equation is then applied with the three estimated statistics to compute the discharge at selected exceedance probabilities. Standard errors at the 2-percent exceedance probability range from 41 to 90 percent. (USGS)

  6. Comparing Hp(3) evaluated from the conversion coefficients from air kerma to personal dose equivalent for eye lens dosimetry calibrated on a new cylindrical PMMA phantom

    NASA Astrophysics Data System (ADS)

    Esor, J.; Sudchai, W.; Monthonwattana, S.; Pungkun, V.; Intang, A.

    2017-06-01

    Based on a new occupational dose limit recommended by ICRP (2011), the annual dose limit for the lens of the eye for workers should be reduced from 150 mSv/y to 20 mSv/y averaged over 5 consecutive years in which no single year exceeding 50 mSv. This new dose limit directly affects radiologists and cardiologists whose work involves high radiation exposure over 20 mSv/y. Eye lens dosimetry (Hp(3)) has become increasingly important and should be evaluated directly based on dosimeters that are worn closely to the eye. Normally, Hp(3) dose algorithm was carried out by the combination of Hp(0.07) and Hp(10) values while dosimeters were calibrated on slab PMMA phantom. Recently, there were three reports from European Union that have shown the conversion coefficients from air kerma to Hp(3). These conversion coefficients carried out by ORAMED, PTB and CEA Saclay projects were performed by using a new cylindrical head phantom. In this study, various delivered doses were calculated using those three conversion coefficients while nanoDot, small OSL dosimeters, were used for Hp(3) measurement. These calibrations were performed with a standard X-ray generator at Secondary Standard Dosimetry Laboratory (SSDL). Delivered doses (Hp(3)) using those three conversion coefficients were compared with Hp(3) from nanoDot measurements. The results showed that percentage differences between delivered doses evaluated from the conversion coefficient of each project and Hp(3) doses evaluated from the nanoDots were found to be not exceeding -11.48 %, -8.85 % and -8.85 % for ORAMED, PTB and CEA Saclay project, respectively.

  7. Experimental investigation of turbulent diffusion of slightly buoyant droplets in locally isotropic turbulence

    NASA Astrophysics Data System (ADS)

    Gopalan, Balaji; Malkiel, Edwin; Katz, Joseph

    2008-09-01

    High-speed inline digital holographic cinematography is used for studying turbulent diffusion of slightly buoyant 0.5-1.2 mm diameter diesel droplets and 50 μm diameter neutral density particles. Experiments are performed in a 50×50×70 mm3 sample volume in a controlled, nearly isotropic turbulence facility, which is characterized by two dimensional particle image velocimetry. An automated tracking program has been used for measuring velocity time history of more than 17 000 droplets and 15 000 particles. For most of the present conditions, rms values of horizontal droplet velocity exceed those of the fluid. The rms values of droplet vertical velocity are higher than those of the fluid only for the highest turbulence level. The turbulent diffusion coefficient is calculated by integration of the ensemble-averaged Lagrangian velocity autocovariance. Trends of the asymptotic droplet diffusion coefficient are examined by noting that it can be viewed as a product of a mean square velocity and a diffusion time scale. To compare the effects of turbulence and buoyancy, the turbulence intensity (ui') is scaled by the droplet quiescent rise velocity (Uq). The droplet diffusion coefficients in horizontal and vertical directions are lower than those of the fluid at low normalized turbulence intensity, but exceed it with increasing normalized turbulence intensity. For most of the present conditions the droplet horizontal diffusion coefficient is higher than the vertical diffusion coefficient, consistent with trends of the droplet velocity fluctuations and in contrast to the trends of the diffusion timescales. The droplet diffusion coefficients scaled by the product of turbulence intensity and an integral length scale are a monotonically increasing function of ui'/Uq.

  8. Dynamic analysis of a fibre-optic ring resonator excited by a sinewave-modulated laser diode

    NASA Astrophysics Data System (ADS)

    Pandian, G. Soundra; Seraji, Faramarz

    1990-10-01

    The present theoretical dynamic analysis of a fiber-optic ring resonator upon excitation by a sinusoidally-modulated laser diode (LD) yields results for such resonator conditions as modulating frequency, amplitude-modulation index, coupler power-coupling coefficient, loop-delay time (tau), and the phase angle between the LD's AM and FM responses. It is found that when the modulation frequency f(m) exceeds a threshold value such that f(m)tau exceeds 0.0002, the output response diverges from steady state and engages in an oscillatory behavior characterized by overshoots. When f(m)tau exceeds 1.0, the output approximates the intensity modulation of the LD.

  9. Probability density and exceedance rate functions of locally Gaussian turbulence

    NASA Technical Reports Server (NTRS)

    Mark, W. D.

    1989-01-01

    A locally Gaussian model of turbulence velocities is postulated which consists of the superposition of a slowly varying strictly Gaussian component representing slow temporal changes in the mean wind speed and a more rapidly varying locally Gaussian turbulence component possessing a temporally fluctuating local variance. Series expansions of the probability density and exceedance rate functions of the turbulence velocity model, based on Taylor's series, are derived. Comparisons of the resulting two-term approximations with measured probability density and exceedance rate functions of atmospheric turbulence velocity records show encouraging agreement, thereby confirming the consistency of the measured records with the locally Gaussian model. Explicit formulas are derived for computing all required expansion coefficients from measured turbulence records.

  10. Anthropometry of Women of the U.S. Army--1977. Report Number 4. Correlation Coefficients

    DTIC Science & Technology

    1980-02-01

    S.... •, 0 76 x:. ADo5 //64 ! TECHNICAL REPORT NATICK/TR-80/016 (/ II ANTHROPOMETRY OF WOMEN OF THE U.S. ARMY-1977 Report No. 4 Correlation...NUMBER NATICK/TR-80/016 4. TITLE (and Subtitle) 5. TYPE OF REPORT & PERIOD COVERED ANTHROPOMETRY OF WOMEN OF THE U.S. ARMY--1977 Technical Report REPORT NO... Anthropometry Survey(s) Coefficients of correlation Measurement(s) U.S. Army Correlation coefficients Body size Military personnel Equation(s) Sizes

  11. Concurrent validation and reliability of digital image analysis of granulation tissue color for clinical pressure ulcers.

    PubMed

    Iizaka, Shinji; Sugama, Junko; Nakagami, Gojiro; Kaitani, Toshiko; Naito, Ayumi; Koyanagi, Hiroe; Matsuo, Junko; Kadono, Takafumi; Konya, Chizuko; Sanada, Hiromi

    2011-01-01

    Granulation tissue color is one indicator for pressure ulcer (PU) assessment. However, it entails a subjective evaluation only, and quantitative methods have not been established. We developed color indicators from digital image analysis and investigated their concurrent validity and reliability for clinical PUs. A cross-sectional study was conducted on 47 patients with 55 full-thickness PUs. After color calibration, a wound photograph was converted into three images representing red color: erythema index (EI), modified erythema index with additional color calibration (granulation red index [GRI]), and , which represents the artificially created red-green axis of L(*) a(*) b(*) color space. The mean intensity of the granulation tissue region and the percentage of pixels exceeding the optimal cutoff intensity (% intensity) were calculated. Mean GRI (ρ=0.39, p=0.007) and (ρ=0.55, p<0.001), as well as their % intensity indicators, showed positive correlations with a(*) measured by tristimulus colorimeter, but erythema index did not. They were correlated with hydroxyproline concentration in wound fluid, healthy granulation tissue area, and blood hemoglobin level. Intra- and interrater reliability of the indicator calculation using both GRI and had an intraclass correlation coefficient >0.9. GRI and from digital image analysis can quantitatively evaluate granulation tissue color of clinical PUs. © 2011 by the Wound Healing Society.

  12. DCCA cross-correlation coefficients reveals the change of both synchronization and oscillation in EEG of Alzheimer disease patients

    NASA Astrophysics Data System (ADS)

    Chen, Yingyuan; Cai, Lihui; Wang, Ruofan; Song, Zhenxi; Deng, Bin; Wang, Jiang; Yu, Haitao

    2018-01-01

    Alzheimer's disease (AD) is a degenerative disorder of neural system that affects mainly the older population. Recently, many researches show that the EEG of AD patients can be characterized by EEG slowing, enhanced complexity of the EEG signals, and EEG synchrony. In order to examine the neural synchrony at multi scales, and to find a biomarker that help detecting AD in diagnosis, detrended cross-correlation analysis (DCCA) of EEG signals is applied in this paper. Several parameters, namely DCCA coefficients in the whole brain, DCCA coefficients at a specific scale, maximum DCCA coefficient over the span of all time scales and the corresponding scale of such coefficients, were extracted to examine the synchronization, respectively. The results show that DCCA coefficients have a trend of increase as scale increases, and decreases as electrode distance increases. Comparing DCCA coefficients in AD patients with healthy controls, a decrease of synchronization in the whole brain, and a bigger scale corresponding to maximum correlation is discovered in AD patients. The change of max-correlation scale may relate to the slowing of oscillatory activities. Linear combination of max DCCA coefficient and max-correlation scale reaches a classification accuracy of 90%. From the above results, it is reasonable to conclude that DCCA coefficient reveals the change of both oscillation and synchrony in AD, and thus is a powerful tool to differentiate AD patients from healthy elderly individuals.

  13. Prediction of penetration rate of rotary-percussive drilling using artificial neural networks - a case study / Prognozowanie postępu wiercenia przy użyciu wiertła udarowo-obrotowego przy wykorzystaniu sztucznych sieci neuronowych - studium przypadku

    NASA Astrophysics Data System (ADS)

    Aalizad, Seyed Ali; Rashidinejad, Farshad

    2012-12-01

    Penetration rate in rocks is one of the most important parameters of determination of drilling economics. Total drilling costs can be determined by predicting the penetration rate and utilized for mine planning. The factors which affect penetration rate are exceedingly numerous and certainly are not completely understood. For the prediction of penetration rate in rotary-percussive drilling, four types of rocks in Sangan mine have been chosen. Sangan is situated in Khorasan-Razavi province in Northeastern Iran. The selected parameters affect penetration rate is divided in three categories: rock properties, drilling condition and drilling pattern. The rock properties are: density, rock quality designation (RQD), uni-axial compressive strength, Brazilian tensile strength, porosity, Mohs hardness, Young modulus, P-wave velocity. Drilling condition parameters are: percussion, rotation, feed (thrust load) and flushing pressure; and parameters for drilling pattern are: blasthole diameter and length. Rock properties were determined in the laboratory, and drilling condition and drilling pattern were determined in the field. For create a correlation between penetration rate and rock properties, drilling condition and drilling pattern, artificial neural networks (ANN) were used. For this purpose, 102 blastholes were observed and drilling condition, drilling pattern and time of drilling in each blasthole were recorded. To obtain a correlation between this data and prediction of penetration rate, MATLAB software was used. To train the pattern of ANN, 77 data has been used and 25 of them found for testing the pattern. Performance of ANN models was assessed through the root mean square error (RMSE) and correlation coefficient (R2). For optimized model (14-14-10-1) RMSE and R2 is 0.1865 and 86%, respectively, and its sensitivity analysis showed that there is a strong correlation between penetration rate and RQD, rotation and blasthole diameter. High correlation coefficient and low root mean square error of these models showed that the ANN is a suitable tool for penetration rate prediction.

  14. Comparative estrogenicity of endogenous, environmental and dietary estrogens in pregnant women I: Serum levels, variability and the basis for urinary biomonitoring of serum estrogenicity

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Fleck, Stefanie C.; Twaddle, Nathan C.; Churchwell, Mona I.

    Biomonitoring of human exposure to estrogens most frequently focuses on environmental and dietary estrogens, and infrequently includes measures of exposure to potent endogenous estrogens present in serum. Pregnancy is a developmentally sensitive period during which “added” serum estrogenicity exceeding normal intra-individual daily variability may be of particular relevance. Here, we made repeated measurements of serum concentrations of estrone (E1), estradiol (E2), estriol (E3), estetrol (E4), daidzein (DDZ), genistein (GEN) and bisphenol A (BPA) in thirty pregnant women using ultra-performance liquid chromatography coupled with tandem mass spectrometry detection (UPLC-MS/MS) and electrospray ionization (ESI). Serum E1, E2, and E3 concentrations varied significantlymore » (coefficients of variation 9–10%) with broad ranges across the cohort: 1.61–85.1 nM, 9.09–69.7 nM, and 1.5–36.3 nM respectively. BPA (undetected, estimated from total exposure), DDZ and GEN concentrations were 1-5 orders of magnitude lower. The 24-h urinary elimination profiles of endogenous estrogens were each strongly correlated with their corresponding serum concentrations (Pearson's Correlation Coefficients of 0.83 (E1), 0.84 (E2) and 0.94 (E3)). Lastly, a multivariate regression analysis produced equations for estimating serum concentrations of E1, E2, E3, E4, GEN and DDZ from urinary elimination rates and gestation period, an important step towards non-invasive biomonitoring for assessment of “added” estrogenicity during pregnancy.« less

  15. Comparative estrogenicity of endogenous, environmental and dietary estrogens in pregnant women I: Serum levels, variability and the basis for urinary biomonitoring of serum estrogenicity

    DOE PAGES

    Fleck, Stefanie C.; Twaddle, Nathan C.; Churchwell, Mona I.; ...

    2018-03-13

    Biomonitoring of human exposure to estrogens most frequently focuses on environmental and dietary estrogens, and infrequently includes measures of exposure to potent endogenous estrogens present in serum. Pregnancy is a developmentally sensitive period during which “added” serum estrogenicity exceeding normal intra-individual daily variability may be of particular relevance. Here, we made repeated measurements of serum concentrations of estrone (E1), estradiol (E2), estriol (E3), estetrol (E4), daidzein (DDZ), genistein (GEN) and bisphenol A (BPA) in thirty pregnant women using ultra-performance liquid chromatography coupled with tandem mass spectrometry detection (UPLC-MS/MS) and electrospray ionization (ESI). Serum E1, E2, and E3 concentrations varied significantlymore » (coefficients of variation 9–10%) with broad ranges across the cohort: 1.61–85.1 nM, 9.09–69.7 nM, and 1.5–36.3 nM respectively. BPA (undetected, estimated from total exposure), DDZ and GEN concentrations were 1-5 orders of magnitude lower. The 24-h urinary elimination profiles of endogenous estrogens were each strongly correlated with their corresponding serum concentrations (Pearson's Correlation Coefficients of 0.83 (E1), 0.84 (E2) and 0.94 (E3)). Lastly, a multivariate regression analysis produced equations for estimating serum concentrations of E1, E2, E3, E4, GEN and DDZ from urinary elimination rates and gestation period, an important step towards non-invasive biomonitoring for assessment of “added” estrogenicity during pregnancy.« less

  16. SPIROMETRY IN SCHOOLCHILDREN FOR FIELD STUDIES: DOES TESTING ON DIFFERENT DAYS CHANGE THE RESULT OF THE EXAM?

    PubMed Central

    Scalco, Janaina Cristina; Minsky, Rafaela Coelho; Schivinski, Camila Isabel Santos

    2017-01-01

    ABSTRACT Objective: To analyze if there is variation in the results of spirometry performed by healthy schoolchildren on different days. Methods: Cross-sectional study with healthy schoolchildren aged 7 to 12 years old, in Florianópolis, Santa Catarina, Southern Brazil. Prepubescent children, non-athletes, born at full term, without cardiorespiratory, rheumatic, musculoskeletal, neurological and visual or hearing deficit were included. The child’s health was assessed by a health questionnaire and by the survey International Study of Asthma and Allergies in Childhood. The spirometric test was performed on 3 different days, not exceeding the interval of 15 days between the first and last exams, following the guidelines of the American Thoracic Society. The absolute values and percentages of predicted values of forced vital capacity, forced volume in the first second and peak expiratory flow were analyzed. Statistical analysis was performed using the Shapiro-Wilk normality test followed by one-way analysis of variance or Friedman test and by Bonferroni’s post-hoc test for multiple parametric comparisons. Also, the intraclass correlation coefficient was applied to compare results on the same patients on the different tested days. Results: Twenty-two children were analyzed, with a mean age of 9.3±1.1 years. All the spirometric parameters showed a reduction in absolute value after the first exam, but without significant difference. Regarding reproducibility of spirometry results, the tests presented intraclass correlation coefficient >0.70. Conclusions: There was no change in the results of spirometry performed by healthy schoolchildren on three different days. PMID:29160411

  17. Terahertz response of dipolar impurities in polar liquids: On anomalous dielectric absorption of protein solutions

    NASA Astrophysics Data System (ADS)

    Matyushov, Dmitry V.

    2010-02-01

    A theory of radiation absorption by dielectric mixtures is presented. The coarse-grained formulation is based on the wave-vector-dependent correlation functions of molecular dipoles of the host polar liquid and a density structure factor of the solutes. A nonlinear dependence of the dielectric absorption coefficient on the solute concentration is predicted and originates from the mutual polarization of the liquid surrounding the solutes by the collective field of the solute dipoles aligned along the radiation field. The theory is applied to terahertz absorption of hydrated saccharides and proteins. While the theory gives an excellent account of the observations for saccharides, without additional assumptions and fitting parameters, experimental absorption coefficient of protein solutions significantly exceeds theoretical calculations with dipole moment of the bare protein assigned to the solute and shows a peak against the protein concentration. A substantial polarization of protein’s hydration shell, resulting in a net dipole moment, is required to explain the disagreement between theory and experiment. When the correlation function of the total dipole moment of the protein with its hydration shell from numerical simulations is used in the analytical model, an absorption peak, qualitatively similar to that seen in experiment, is obtained. The existence and position of the peak are sensitive to the specifics of the protein-protein interactions. Numerical testing of the theory requires the combination of dielectric and small-angle scattering measurements. The calculations confirm that “elastic ferroelectric bag” of water shells observed in previous numerical simulations is required to explain terahertz dielectric measurements.

  18. Feasibility study of using a Microsoft Kinect for virtual coaching of wheelchair transfer techniques.

    PubMed

    Hwang, Seonhong; Tsai, Chung-Ying; Koontz, Alicia M

    2017-05-24

    The purpose of this study was to test the concurrent validity and test-retest reliability of the Kinect skeleton tracking algorithm for measurement of trunk, shoulder, and elbow joint angle measurement during a wheelchair transfer task. Eight wheelchair users were recruited for this study. Joint positions were recorded simultaneously by the Kinect and Vicon motion capture systems while subjects transferred from their wheelchairs to a level bench. Shoulder, elbow, and trunk angles recorded with the Kinect system followed a similar trajectory as the angles recorded with the Vicon system with correlation coefficients that are larger than 0.71 on both sides (leading arm and trailing arm). The root mean square errors (RMSEs) ranged from 5.18 to 22.46 for the shoulder, elbow, and trunk angles. The 95% limits of agreement (LOA) for the discrepancy between the two systems exceeded the clinical significant level of 5°. For the trunk, shoulder, and elbow angles, the Kinect had very good relative reliability for the measurement of sagittal, frontal and horizontal trunk angles, as indicated by the high intraclass correlation coefficient (ICC) values (>0.90). Small standard error of the measure (SEM) values, indicating good absolute reliability, were observed for all joints except for the leading arm's shoulder joint. Relatively large minimal detectable changes (MDCs) were observed in all joint angles. The Kinect motion tracking has promising performance levels for some upper limb joints. However, more accurate measurement of the joint angles may be required. Therefore, understanding the limitations in precision and accuracy of Kinect is imperative before utilization of Kinect.

  19. The reliability, minimal detectable change and concurrent validity of a gravity-based bubble inclinometer and iphone application for measuring standing lumbar lordosis.

    PubMed

    Salamh, Paul A; Kolber, Morey

    2014-01-01

    To investigate the reliability, minimal detectable change (MDC90) and concurrent validity of a gravity-based bubble inclinometer (inclinometer) and iPhone® application for measuring standing lumbar lordosis. Two investigators used both an inclinometer and an iPhone® with an inclinometer application to measure lumbar lordosis of 30 asymptomatic participants. ICC models 3,k and 2,k were used for the intrarater and interrater analysis, respectively. Good interrater and intrarater reliability was present for the inclinometer with Intraclass Correlation Coefficients (ICC) of 0.90 and 0.85, respectively and the iPhone® application with ICC values of 0.96 and 0.81. The minimal detectable change (MDC90) indicates that a change greater than or equal to 7° and 6° is needed to exceed the threshold of error using the iPhone® and inclinometer, respectively. The concurrent validity between the two instruments was good with a Pearson product-moment coefficient of correlation (r) of 0.86 for both raters. Ninety-five percent limits of agreement identified differences ranging from 9° greater in regards to the iPhone® to 8° less regarding the inclinometer. Both the inclinometer and iPhone® application possess good interrater reliability, intrarater reliability and concurrent validity for measuring standing lumbar lordosis. This investigation provides preliminary evidence to suggest that smart phone applications may offer clinical utility comparable to inclinometry for quantifying standing lumbar lordosis. Clinicians should recognize potential individual differences when using these devices interchangeably.

  20. Short forms of the Child Perceptions Questionnaire for 11–14-year-old children (CPQ11–14): Development and initial evaluation

    PubMed Central

    Jokovic, Aleksandra; Locker, David; Guyatt, Gordan

    2006-01-01

    Background The Child Perceptions Questionnaire for children aged 11 to 14 years (CPQ11–14) is a 37-item measure of oral-health-related quality of life (OHRQoL) encompassing four domains: oral symptoms, functional limitations, emotional and social well-being. To facilitate its use in clinical settings and population-based health surveys, it was shortened to 16 and 8 items. Item impact and stepwise regression methods were used to produce each version. This paper describes the developmental process, compares the discriminative properties of the resulting four short-forms and evaluates their precision relative to the original CPQ11–14. Methods The item impact method used data from the CPQ11–14 item reduction study to select the questions with the highest impact scores in each domain. The regression method, where the dependent variable was the overall CPQ11–14 score and the independent variables its individual questions, was applied to the data collected in the validity study for the CPQ11–14. The measurement properties (i.e. criterion validity, construct validity, internal consistency reliability and test-retest reliability) of all 4 short-forms were evaluated using the data from the validity and reliability studies for the CPQ11–14. Results All short forms detected substantial variability in children's OHRQoL. The mean scores on the two 16-item questionnaires were almost identical, while on the two 8-item questionnaires they differed by only one score point. The mean scores standardized to 0–100 were higher on the short forms than the original CPQ11–14 (p < 0.001). There were strong significant correlations between all short-form scores and CPQ11–14 scores (0.87–0.98; p < 0.001). Hypotheses concerning construct validity were confirmed: the short-forms' scores were highest in the oro-facial, lower in the orthodontic and lowest in the paediatric dentistry group; all short-form questionnaires were positively correlated with the ratings of oral health and overall well-being, with the correlation coefficient being higher for the latter. The relative validity coefficients were 0.85 to 1.18. Cronbach's alpha and intraclass correlation coefficients ranged 0.71–0.83 and 0.71–0.77, respectively. Conclusion All short forms demonstrated excellent criterion validity and good construct validity. The reliability coefficients exceeded standards for group-level comparisons. However, these are preliminary findings based on the convenience sampling and further testing in replicated studies involving clinical and general samples of children in various settings is necessary to establish measurement sensitivity and discriminative properties of these questionnaires. PMID:16423298

  1. Indirect Measurement of Local Condensing Heat-Transfer Coefficient Around Horizontal Finned Tubes

    DTIC Science & Technology

    1987-09-01

    vapor-sidp coefficients exceeded Nusselt values by factors of approximately 7 to 9 (for a constant temperature drop across the condensate film). Honda...3/8 in.) diameter water-cooled copper tubes helically coiled to a height of 457 mm (le In.). The auxiliary condenser was cooled by a continuous...NAVAL POSTGRADUATE SCHOOL Monterey, California , " I - . 0) I DECI 41987S:,• c ý ! i, THESIS INDIRECT MEASUREMENT OF LOCAL CONDENSING HEAT-TRANSFER

  2. Statistics corner: A guide to appropriate use of correlation coefficient in medical research.

    PubMed

    Mukaka, M M

    2012-09-01

    Correlation is a statistical method used to assess a possible linear association between two continuous variables. It is simple both to calculate and to interpret. However, misuse of correlation is so common among researchers that some statisticians have wished that the method had never been devised at all. The aim of this article is to provide a guide to appropriate use of correlation in medical research and to highlight some misuse. Examples of the applications of the correlation coefficient have been provided using data from statistical simulations as well as real data. Rule of thumb for interpreting size of a correlation coefficient has been provided.

  3. [Correlation of molecular weight and nanofiltration mass transfer coefficient of phenolic acid composition from Salvia miltiorrhiza].

    PubMed

    Li, Cun-Yu; Wu, Xin; Gu, Jia-Mei; Li, Hong-Yang; Peng, Guo-Ping

    2018-04-01

    Based on the molecular sieving and solution-diffusion effect in nanofiltration separation, the correlation between initial concentration and mass transfer coefficient of three typical phenolic acids from Salvia miltiorrhiza was fitted to analyze the relationship among mass transfer coefficient, molecular weight and concentration. The experiment showed a linear relationship between operation pressure and membrane flux. Meanwhile, the membrane flux was gradually decayed with the increase of solute concentration. On the basis of the molecular sieving and solution-diffusion effect, the mass transfer coefficient and initial concentration of three phenolic acids showed a power function relationship, and the regression coefficients were all greater than 0.9. The mass transfer coefficient and molecular weight of three phenolic acids were negatively correlated with each other, and the order from high to low is protocatechualdehyde >rosmarinic acid> salvianolic acid B. The separation mechanism of nanofiltration for phenolic acids was further clarified through the analysis of the correlation of molecular weight and nanofiltration mass transfer coefficient. The findings provide references for nanofiltration separation, especially for traditional Chinese medicine with phenolic acids. Copyright© by the Chinese Pharmaceutical Association.

  4. Biostatistics Series Module 6: Correlation and Linear Regression.

    PubMed

    Hazra, Avijit; Gogtay, Nithya

    2016-01-01

    Correlation and linear regression are the most commonly used techniques for quantifying the association between two numeric variables. Correlation quantifies the strength of the linear relationship between paired variables, expressing this as a correlation coefficient. If both variables x and y are normally distributed, we calculate Pearson's correlation coefficient ( r ). If normality assumption is not met for one or both variables in a correlation analysis, a rank correlation coefficient, such as Spearman's rho (ρ) may be calculated. A hypothesis test of correlation tests whether the linear relationship between the two variables holds in the underlying population, in which case it returns a P < 0.05. A 95% confidence interval of the correlation coefficient can also be calculated for an idea of the correlation in the population. The value r 2 denotes the proportion of the variability of the dependent variable y that can be attributed to its linear relation with the independent variable x and is called the coefficient of determination. Linear regression is a technique that attempts to link two correlated variables x and y in the form of a mathematical equation ( y = a + bx ), such that given the value of one variable the other may be predicted. In general, the method of least squares is applied to obtain the equation of the regression line. Correlation and linear regression analysis are based on certain assumptions pertaining to the data sets. If these assumptions are not met, misleading conclusions may be drawn. The first assumption is that of linear relationship between the two variables. A scatter plot is essential before embarking on any correlation-regression analysis to show that this is indeed the case. Outliers or clustering within data sets can distort the correlation coefficient value. Finally, it is vital to remember that though strong correlation can be a pointer toward causation, the two are not synonymous.

  5. Biostatistics Series Module 6: Correlation and Linear Regression

    PubMed Central

    Hazra, Avijit; Gogtay, Nithya

    2016-01-01

    Correlation and linear regression are the most commonly used techniques for quantifying the association between two numeric variables. Correlation quantifies the strength of the linear relationship between paired variables, expressing this as a correlation coefficient. If both variables x and y are normally distributed, we calculate Pearson's correlation coefficient (r). If normality assumption is not met for one or both variables in a correlation analysis, a rank correlation coefficient, such as Spearman's rho (ρ) may be calculated. A hypothesis test of correlation tests whether the linear relationship between the two variables holds in the underlying population, in which case it returns a P < 0.05. A 95% confidence interval of the correlation coefficient can also be calculated for an idea of the correlation in the population. The value r2 denotes the proportion of the variability of the dependent variable y that can be attributed to its linear relation with the independent variable x and is called the coefficient of determination. Linear regression is a technique that attempts to link two correlated variables x and y in the form of a mathematical equation (y = a + bx), such that given the value of one variable the other may be predicted. In general, the method of least squares is applied to obtain the equation of the regression line. Correlation and linear regression analysis are based on certain assumptions pertaining to the data sets. If these assumptions are not met, misleading conclusions may be drawn. The first assumption is that of linear relationship between the two variables. A scatter plot is essential before embarking on any correlation-regression analysis to show that this is indeed the case. Outliers or clustering within data sets can distort the correlation coefficient value. Finally, it is vital to remember that though strong correlation can be a pointer toward causation, the two are not synonymous. PMID:27904175

  6. A comparison of confidence interval methods for the intraclass correlation coefficient in community-based cluster randomization trials with a binary outcome.

    PubMed

    Braschel, Melissa C; Svec, Ivana; Darlington, Gerarda A; Donner, Allan

    2016-04-01

    Many investigators rely on previously published point estimates of the intraclass correlation coefficient rather than on their associated confidence intervals to determine the required size of a newly planned cluster randomized trial. Although confidence interval methods for the intraclass correlation coefficient that can be applied to community-based trials have been developed for a continuous outcome variable, fewer methods exist for a binary outcome variable. The aim of this study is to evaluate confidence interval methods for the intraclass correlation coefficient applied to binary outcomes in community intervention trials enrolling a small number of large clusters. Existing methods for confidence interval construction are examined and compared to a new ad hoc approach based on dividing clusters into a large number of smaller sub-clusters and subsequently applying existing methods to the resulting data. Monte Carlo simulation is used to assess the width and coverage of confidence intervals for the intraclass correlation coefficient based on Smith's large sample approximation of the standard error of the one-way analysis of variance estimator, an inverted modified Wald test for the Fleiss-Cuzick estimator, and intervals constructed using a bootstrap-t applied to a variance-stabilizing transformation of the intraclass correlation coefficient estimate. In addition, a new approach is applied in which clusters are randomly divided into a large number of smaller sub-clusters with the same methods applied to these data (with the exception of the bootstrap-t interval, which assumes large cluster sizes). These methods are also applied to a cluster randomized trial on adolescent tobacco use for illustration. When applied to a binary outcome variable in a small number of large clusters, existing confidence interval methods for the intraclass correlation coefficient provide poor coverage. However, confidence intervals constructed using the new approach combined with Smith's method provide nominal or close to nominal coverage when the intraclass correlation coefficient is small (<0.05), as is the case in most community intervention trials. This study concludes that when a binary outcome variable is measured in a small number of large clusters, confidence intervals for the intraclass correlation coefficient may be constructed by dividing existing clusters into sub-clusters (e.g. groups of 5) and using Smith's method. The resulting confidence intervals provide nominal or close to nominal coverage across a wide range of parameters when the intraclass correlation coefficient is small (<0.05). Application of this method should provide investigators with a better understanding of the uncertainty associated with a point estimator of the intraclass correlation coefficient used for determining the sample size needed for a newly designed community-based trial. © The Author(s) 2015.

  7. Inventory of forest resources (including water) by multi-level sampling. [nine northern Virginia coastal plain counties

    NASA Technical Reports Server (NTRS)

    Aldrich, R. C.; Dana, R. W.; Roberts, E. H. (Principal Investigator)

    1977-01-01

    The author has identified the following significant results. A stratified random sample using LANDSAT band 5 and 7 panchromatic prints resulted in estimates of water in counties with sampling errors less than + or - 9% (67% probability level). A forest inventory using a four band LANDSAT color composite resulted in estimates of forest area by counties that were within + or - 6.7% and + or - 3.7% respectively (67% probability level). Estimates of forest area for counties by computer assisted techniques were within + or - 21% of operational forest survey figures and for all counties the difference was only one percent. Correlations of airborne terrain reflectance measurements with LANDSAT radiance verified a linear atmospheric model with an additive (path radiance) term and multiplicative (transmittance) term. Coefficients of determination for 28 of the 32 modeling attempts, not adverseley affected by rain shower occurring between the times of LANDSAT passage and aircraft overflights, exceeded 0.83.

  8. Demonstration and evaluation of a method for assessing mediated moderation.

    PubMed

    Morgan-Lopez, Antonio A; MacKinnon, David P

    2006-02-01

    Mediated moderation occurs when the interaction between two variables affects a mediator, which then affects a dependent variable. In this article, we describe the mediated moderation model and evaluate it with a statistical simulation using an adaptation of product-of-coefficients methods to assess mediation. We also demonstrate the use of this method with a substantive example from the adolescent tobacco literature. In the simulation, relative bias (RB) in point estimates and standard errors did not exceed problematic levels of +/- 10% although systematic variability in RB was accounted for by parameter size, sample size, and nonzero direct effects. Power to detect mediated moderation effects appears to be severely compromised under one particular combination of conditions: when the component variables that make up the interaction terms are correlated and partial mediated moderation exists. Implications for the estimation of mediated moderation effects in experimental and nonexperimental research are discussed.

  9. Fiber-optic miniature sensor for in situ temperature monitoring of curing composite material

    NASA Astrophysics Data System (ADS)

    Sampath, Umesh; Kim, Dae-gil; Kim, Hyunjin; Song, Minho

    2018-04-01

    This study proposes a fiber-optic temperature sensor with a single-mode fiber tip covered with a thermo-sensitive polymer resin. The temperature is sensed by measuring the Fresnel reflection from the optical fiber/polymer interface. Because the thermo-optic coefficients differ between the optical fiber and the polymer, the in situ temperature can be measured even in curing composite materials. In initial experiments, the proposed sensor successfully measured and recovered the temperature information. The measured sensor data were linearly correlated, with an R2 exceeding 0.99. The standard deviation in the long-term measurements of constant temperature was 2.6%. The durability and stability of the sensor head material in long-term operation was validated by Fourier transform infrared spectroscopy and X-ray diffraction analysis. In further experiments, the suggested miniature temperature sensor obtained the internal temperatures of curing composite material over a wide range (30-110 °C).

  10. Snapping Sharks, Maddening Mindreaders, and Interactive Images: Teaching Correlation.

    ERIC Educational Resources Information Center

    Mitchell, Mark L.

    Understanding correlation coefficients is difficult for students. A free computer program that helps introductory psychology students distinguish between positive and negative correlation, and which also teaches them to understand the differences between correlation coefficients of different size is described in this paper. The program is…

  11. Prediction of static friction coefficient in rough contacts based on the junction growth theory

    NASA Astrophysics Data System (ADS)

    Spinu, S.; Cerlinca, D.

    2017-08-01

    The classic approach to the slip-stick contact is based on the framework advanced by Mindlin, in which localized slip occurs on the contact area when the local shear traction exceeds the product between the local pressure and the static friction coefficient. This assumption may be too conservative in the case of high tractions arising at the asperities tips in the contact of rough surfaces, because the shear traction may be allowed to exceed the shear strength of the softer material. Consequently, the classic frictional contact model is modified in this paper so that gross sliding occurs when the junctions formed between all contacting asperities are independently sheared. In this framework, when the contact tractions, normal and shear, exceed the hardness of the softer material on the entire contact area, the material of the asperities yields and the junction growth process ends in all contact regions, leading to gross sliding inception. This friction mechanism is implemented in a previously proposed numerical model for the Cattaneo-Mindlin slip-stick contact problem, which is modified to accommodate the junction growth theory. The frictionless normal contact problem is solved first, then the tangential force is gradually increased, until gross sliding inception. The contact problems in the normal and in the tangential direction are successively solved, until one is stabilized in relation to the other. The maximum tangential force leading to a non-vanishing stick area is the static friction force that can be sustained by the rough contact. The static friction coefficient is eventually derived as the ratio between the latter friction force and the normal force.

  12. 40 CFR 53.34 - Test procedure for methods for PM10 and Class I methods for PM2.5.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... linear regression parameters (slope, intercept, and correlation coefficient) describing the relationship... correlation coefficient. (2) To pass the test for comparability, the slope, intercept, and correlation...

  13. [Prediction of soil adsorption coefficients of organic compounds in a wide range of soil types by soil column liquid chromatography].

    PubMed

    Guo, Rongbo; Chen, Jiping; Zhang, Qing; Wu, Wenzhong; Liang, Xinmiao

    2004-01-01

    Using the methanol-water mixtures as mobile phases of soil column liquid chromatography (SCLC), prediction of soil adsorption coefficients (K(d)) by SCLC was validated in a wide range of soil types. The correlations between the retention factors measured by SCLC and soil adsorption coefficients measured by batch experiments were studied for five soils with different properties, i.e., Eurosoil 1#, 2#, 3#, 4# and 5#. The results show that good correlations existed between the retention factors and soil adsorption coefficients for Eurosoil 1#, 2#, 3# and 4#. For Eurosoil 5# which has a pH value of near 3, the correlation between retention factors and soil adsorption coefficients was unsatisfactory using methanol-water as mobile phase of SCLC. However, a good correlation was obtained using a methanol-buffer mixture with pH 3 as the mobile phase. This study proved that the SCLC is suitable for the prediction of soil adsorption coefficients.

  14. Contribution of cod liver oil-related nutrients (vitamins A, D, E and eicosapentaenoic acid and docosahexaenoic acid) to daily nutrient intake and their associations with plasma concentrations in the EPIC-Norfolk cohort

    PubMed Central

    Lentjes, M A H; Mulligan, A A; Welch, A A; Bhaniani, A; Luben, R N; Khaw, K–T

    2015-01-01

    Background Total nutrient intake (TNI) is intake from food and supplements. This provides an assessment of nutrient adequacy and the prevalence of excessive intake, as well as the response with respect to biomarkers. Cod liver oil (CLO) is the most frequently consumed supplement in the UK, containing nutrients that might have varying influences on health. We calculated TNI for vitamins A, D and E, as well as eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), and assessed associations with the respective blood concentrations. Methods Seven-day diet diaries and blood samples were taken from two subsets of the European Prospective Investigation into Cancer (EPIC-Norfolk) cohort (age range 39–79 years; n = 1400 for vitamin D; n = 6656 for remaining nutrients). TNI was calculated for the subgroups: nonsupplement users, those consuming the nutrient in supplement form and those consuming a supplement without this nutrient. Results CLO-related nutrients were supplemented by 15%–33%, which approximately doubled median intakes. Almost everyone in the supplement + vitamin A group reached the estimated average requirement; however, guideline levels were likely to be exceeded. Partial correlations between intake of vitamins A and D and biomarkers were low and modestly strengthened by the inclusion of supplement sources (correlation = 0.01–0.13). Correlations between biomarker and TNI of vitamin E and EPA+DHA were in the range 0.40–0.46; however, vitamin E exceeding food intake resulted in attenuated coefficients. Linear associations between food or TNI EPA+DHA and plasma were weak but consistent across subgroups. Conclusions CLO-related nutrients contribute substantially to nutrient intake, with a risk of over-consumption. Apart from EPA+DHA, biomarker data suggest that CLO-related nutrients in supplements are not linearly associated with vitamin status. PMID:25228113

  15. Contribution of cod liver oil-related nutrients (vitamins A, D, E and eicosapentaenoic acid and docosahexaenoic acid) to daily nutrient intake and their associations with plasma concentrations in the EPIC-Norfolk cohort.

    PubMed

    Lentjes, M A H; Mulligan, A A; Welch, A A; Bhaniani, A; Luben, R N; Khaw, K-T

    2015-12-01

    Total nutrient intake (TNI) is intake from food and supplements. This provides an assessment of nutrient adequacy and the prevalence of excessive intake, as well as the response with respect to biomarkers. Cod liver oil (CLO) is the most frequently consumed supplement in the UK, containing nutrients that might have varying influences on health. We calculated TNI for vitamins A, D and E, as well as eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), and assessed associations with the respective blood concentrations. Seven-day diet diaries and blood samples were taken from two subsets of the European Prospective Investigation into Cancer (EPIC-Norfolk) cohort (age range 39-79 years; n = 1400 for vitamin D; n = 6656 for remaining nutrients). TNI was calculated for the subgroups: nonsupplement users, those consuming the nutrient in supplement form and those consuming a supplement without this nutrient. CLO-related nutrients were supplemented by 15%-33%, which approximately doubled median intakes. Almost everyone in the supplement + vitamin A group reached the estimated average requirement; however, guideline levels were likely to be exceeded. Partial correlations between intake of vitamins A and D and biomarkers were low and modestly strengthened by the inclusion of supplement sources (correlation = 0.01-0.13). Correlations between biomarker and TNI of vitamin E and EPA+DHA were in the range 0.40-0.46; however, vitamin E exceeding food intake resulted in attenuated coefficients. Linear associations between food or TNI EPA+DHA and plasma were weak but consistent across subgroups. CLO-related nutrients contribute substantially to nutrient intake, with a risk of over-consumption. Apart from EPA+DHA, biomarker data suggest that CLO-related nutrients in supplements are not linearly associated with vitamin status. © 2014 Authors. Journal of Human Nutrition and Dietetics published by John Wiley & Sons Ltd on behalf of British Dietetic Association.

  16. Temporal correlation coefficient for directed networks.

    PubMed

    Büttner, Kathrin; Salau, Jennifer; Krieter, Joachim

    2016-01-01

    Previous studies dealing with network theory focused mainly on the static aggregation of edges over specific time window lengths. Thus, most of the dynamic information gets lost. To assess the quality of such a static aggregation the temporal correlation coefficient can be calculated. It measures the overall possibility for an edge to persist between two consecutive snapshots. Up to now, this measure is only defined for undirected networks. Therefore, we introduce the adaption of the temporal correlation coefficient to directed networks. This new methodology enables the distinction between ingoing and outgoing edges. Besides a small example network presenting the single calculation steps, we also calculated the proposed measurements for a real pig trade network to emphasize the importance of considering the edge direction. The farm types at the beginning of the pork supply chain showed clearly higher values for the outgoing temporal correlation coefficient compared to the farm types at the end of the pork supply chain. These farm types showed higher values for the ingoing temporal correlation coefficient. The temporal correlation coefficient is a valuable tool to understand the structural dynamics of these systems, as it assesses the consistency of the edge configuration. The adaption of this measure for directed networks may help to preserve meaningful additional information about the investigated network that might get lost if the edge directions are ignored.

  17. Correlation characteristics of phase and amplitude chimeras in an ensemble of nonlocally coupled maps

    NASA Astrophysics Data System (ADS)

    Vadivasova, T. E.; Strelkova, G. I.; Bogomolov, S. A.; Anishchenko, V. S.

    2017-01-01

    Correlation characteristics of chimera states have been calculated using the coefficient of mutual correlation of elements in a closed-ring ensemble of nonlocally coupled chaotic maps. Quantitative differences between the coefficients of mutual correlation for phase and amplitude chimeras are established for the first time.

  18. Comparison of RNFL thickness and RPE-normalized RNFL attenuation coefficient for glaucoma diagnosis

    NASA Astrophysics Data System (ADS)

    Vermeer, K. A.; van der Schoot, J.; Lemij, H. G.; de Boer, J. F.

    2013-03-01

    Recently, a method to determine the retinal nerve fiber layer (RNFL) attenuation coefficient, based on normalization on the retinal pigment epithelium, was introduced. In contrast to conventional RNFL thickness measures, this novel measure represents a scattering property of the RNFL tissue. In this paper, we compare the RNFL thickness and the RNFL attenuation coefficient on 10 normal and 8 glaucomatous eyes by analyzing the correlation coefficient and the receiver operator curves (ROCs). The thickness and attenuation coefficient showed moderate correlation (r=0.82). Smaller correlation coefficients were found within normal (r=0.55) and glaucomatous (r=0.48) eyes. The full separation between normal and glaucomatous eyes based on the RNFL attenuation coefficient yielded an area under the ROC (AROC) of 1.0. The AROC for the RNFL thickness was 0.9875. No statistically significant difference between the two measures was found by comparing the AROC. RNFL attenuation coefficients may thus replace current RNFL thickness measurements or be combined with it to improve glaucoma diagnosis.

  19. Channel correlation of free space optical communication systems with receiver diversity in non-Kolmogorov atmospheric turbulence

    NASA Astrophysics Data System (ADS)

    Ma, Jing; Fu, Yulong; Tan, Liying; Yu, Siyuan; Xie, Xiaolong

    2018-05-01

    Spatial diversity as an effective technique to mitigate the turbulence fading has been widely utilized in free space optical (FSO) communication systems. The received signals, however, will suffer from channel correlation due to insufficient spacing between component antennas. In this paper, the new expressions of the channel correlation coefficient and specifically its components (the large- and small-scale channel correlation coefficients) for a plane wave with aperture effects are derived for horizontal link in moderate-to-strong turbulence, using a non-Kolmogorov spectrum that has a generalized power law in the range of 3-4 instead of the fixed classical Kolmogorov power law of 11/3. And then the influence of power law variations on the channel correlation coefficient and its components are analysed. The numerical results indicated that various value of the power law lead to varying effects on the channel correlation coefficient and its components. This work will help with the further investigation on the fading correlation in spatial diversity systems.

  20. The Physical Significance of the Synthetic Running Correlation Coefficient and Its Applications in Oceanic and Atmospheric Studies

    NASA Astrophysics Data System (ADS)

    Zhao, Jinping; Cao, Yong; Wang, Xin

    2018-06-01

    In order to study the temporal variations of correlations between two time series, a running correlation coefficient (RCC) could be used. An RCC is calculated for a given time window, and the window is then moved sequentially through time. The current calculation method for RCCs is based on the general definition of the Pearson product-moment correlation coefficient, calculated with the data within the time window, which we call the local running correlation coefficient (LRCC). The LRCC is calculated via the two anomalies corresponding to the two local means, meanwhile, the local means also vary. It is cleared up that the LRCC reflects only the correlation between the two anomalies within the time window but fails to exhibit the contributions of the two varying means. To address this problem, two unchanged means obtained from all available data are adopted to calculate an RCC, which is called the synthetic running correlation coefficient (SRCC). When the anomaly variations are dominant, the two RCCs are similar. However, when the variations of the means are dominant, the difference between the two RCCs becomes obvious. The SRCC reflects the correlations of both the anomaly variations and the variations of the means. Therefore, the SRCCs from different time points are intercomparable. A criterion for the superiority of the RCC algorithm is that the average value of the RCC should be close to the global correlation coefficient calculated using all data. The SRCC always meets this criterion, while the LRCC sometimes fails. Therefore, the SRCC is better than the LRCC for running correlations. We suggest using the SRCC to calculate the RCCs.

  1. Observed intra-cluster correlation coefficients in a cluster survey sample of patient encounters in general practice in Australia

    PubMed Central

    Knox, Stephanie A; Chondros, Patty

    2004-01-01

    Background Cluster sample study designs are cost effective, however cluster samples violate the simple random sample assumption of independence of observations. Failure to account for the intra-cluster correlation of observations when sampling through clusters may lead to an under-powered study. Researchers therefore need estimates of intra-cluster correlation for a range of outcomes to calculate sample size. We report intra-cluster correlation coefficients observed within a large-scale cross-sectional study of general practice in Australia, where the general practitioner (GP) was the primary sampling unit and the patient encounter was the unit of inference. Methods Each year the Bettering the Evaluation and Care of Health (BEACH) study recruits a random sample of approximately 1,000 GPs across Australia. Each GP completes details of 100 consecutive patient encounters. Intra-cluster correlation coefficients were estimated for patient demographics, morbidity managed and treatments received. Intra-cluster correlation coefficients were estimated for descriptive outcomes and for associations between outcomes and predictors and were compared across two independent samples of GPs drawn three years apart. Results Between April 1999 and March 2000, a random sample of 1,047 Australian general practitioners recorded details of 104,700 patient encounters. Intra-cluster correlation coefficients for patient demographics ranged from 0.055 for patient sex to 0.451 for language spoken at home. Intra-cluster correlations for morbidity variables ranged from 0.005 for the management of eye problems to 0.059 for management of psychological problems. Intra-cluster correlation for the association between two variables was smaller than the descriptive intra-cluster correlation of each variable. When compared with the April 2002 to March 2003 sample (1,008 GPs) the estimated intra-cluster correlation coefficients were found to be consistent across samples. Conclusions The demonstrated precision and reliability of the estimated intra-cluster correlations indicate that these coefficients will be useful for calculating sample sizes in future general practice surveys that use the GP as the primary sampling unit. PMID:15613248

  2. A comparison of fuzzy logic and cluster renewal approaches for heat transfer modeling in a 1296 t/h CFB boiler with low level of flue gas recirculation

    NASA Astrophysics Data System (ADS)

    Błaszczuk, Artur; Krzywański, Jarosław

    2017-03-01

    The interrelation between fuzzy logic and cluster renewal approaches for heat transfer modeling in a circulating fluidized bed (CFB) has been established based on a local furnace data. The furnace data have been measured in a 1296 t/h CFB boiler with low level of flue gas recirculation. In the present study, the bed temperature and suspension density were treated as experimental variables along the furnace height. The measured bed temperature and suspension density were varied in the range of 1131-1156 K and 1.93-6.32 kg/m3, respectively. Using the heat transfer coefficient for commercial CFB combustor, two empirical heat transfer correlation were developed in terms of important operating parameters including bed temperature and also suspension density. The fuzzy logic results were found to be in good agreement with the corresponding experimental heat transfer data obtained based on cluster renewal approach. The predicted bed-to-wall heat transfer coefficient covered a range of 109-241 W/(m2K) and 111-240 W/(m2K), for fuzzy logic and cluster renewal approach respectively. The divergence in calculated heat flux recovery along the furnace height between fuzzy logic and cluster renewal approach did not exceeded ±2%.

  3. How Much Global Burned Area Can Be Forecast on Seasonal Time Scales Using Sea Surface Temperatures?

    NASA Technical Reports Server (NTRS)

    Chen, Yang; Morton, Douglas C.; Andela, Niels; Giglio, Louis; Randerson, James T.

    2016-01-01

    Large-scale sea surface temperature (SST) patterns influence the interannual variability of burned area in many regions by means of climate controls on fuel continuity, amount, and moisture content. Some of the variability in burned area is predictable on seasonal timescales because fuel characteristics respond to the cumulative effects of climate prior to the onset of the fire season. Here we systematically evaluated the degree to which annual burned area from the Global Fire Emissions Database version 4 with small fires (GFED4s) can be predicted using SSTs from 14 different ocean regions. We found that about 48 of global burned area can be forecast with a correlation coefficient that is significant at a p < 0.01 level using a single ocean climate index (OCI) 3 or more months prior to the month of peak burning. Continental regions where burned area had a higher degree of predictability included equatorial Asia, where 92% of the burned area exceeded the correlation threshold, and Central America, where 86% of the burned area exceeded this threshold. Pacific Ocean indices describing the El Nino-Southern Oscillation were more important than indices from other ocean basins, accounting for about 1/3 of the total predictable global burned area. A model that combined two indices from different oceans considerably improved model performance, suggesting that fires in many regions respond to forcing from more than one ocean basin. Using OCI-burned area relationships and a clustering algorithm, we identified 12 hotspot regions in which fires had a consistent response to SST patterns. Annual burned area in these regions can be predicted with moderate confidence levels, suggesting operational forecasts may be possible with the aim of improving ecosystem management.

  4. Status of serum-calcium and -albumin measurement in Argentina assessed in 300 representative laboratories with 20 fresh frozen single donation sera.

    PubMed

    Stepman, Hedwig C M; Stöckl, Dietmar; Acheme, Rosana; Sesini, Sandra; Mazziotta, Daniel; Thienpont, Linda M

    2011-11-01

    The Fundación Bioquímica Argentina (FBA) performs external quality assessment (EQA) of >3200 laboratories. However, FBA realizes that sample non-commutability and predominant use of heterogeneous systems may bias the estimated performance and standardization status. To eliminate these confounding factors, a study using frozen single donation sera was undertaken with the focus on serum-calcium and -albumin measurement. Target values were established from the results produced with homogeneous systems. In groups of n=7, system effects were investigated. Laboratory performance was evaluated from the correlation coefficient r between the measurement results for all sera and the target values. This allowed ranking of the laboratories and judgment of the deviation for individual samples (total error) against a 10% limit. The total error specification was a deviation for ≥ 5 samples exceeding 10% and/or causing a result outside the laboratory's reference interval. For calcium (n=303) (range: 2.06-2.42 mmol/L), 81 laboratories had an r-value <0.6, 43 even <0.4; the total error was relevant for 97 (10% limit) and 111 (reference interval) laboratories. For albumin (n=311) (range: 34.7-45.7 g/L) r was <0.7 (<0.4) in 44 (16) laboratories; 83 and 36 laboratories exceeded the total error criteria. Laboratories using homogeneous systems were generally ranked higher by correlation. System effects were moderate for calcium, but significant for albumin. The study demonstrated the need to improve the quality and harmonization of calcium and albumin testing in the investigated laboratories. To achieve this objective, we promote co-operation between laboratories, EQA provider and manufacturers.

  5. Feature Genes Selection Using Supervised Locally Linear Embedding and Correlation Coefficient for Microarray Classification

    PubMed Central

    Wang, Yun; Huang, Fangzhou

    2018-01-01

    The selection of feature genes with high recognition ability from the gene expression profiles has gained great significance in biology. However, most of the existing methods have a high time complexity and poor classification performance. Motivated by this, an effective feature selection method, called supervised locally linear embedding and Spearman's rank correlation coefficient (SLLE-SC2), is proposed which is based on the concept of locally linear embedding and correlation coefficient algorithms. Supervised locally linear embedding takes into account class label information and improves the classification performance. Furthermore, Spearman's rank correlation coefficient is used to remove the coexpression genes. The experiment results obtained on four public tumor microarray datasets illustrate that our method is valid and feasible. PMID:29666661

  6. Feature Genes Selection Using Supervised Locally Linear Embedding and Correlation Coefficient for Microarray Classification.

    PubMed

    Xu, Jiucheng; Mu, Huiyu; Wang, Yun; Huang, Fangzhou

    2018-01-01

    The selection of feature genes with high recognition ability from the gene expression profiles has gained great significance in biology. However, most of the existing methods have a high time complexity and poor classification performance. Motivated by this, an effective feature selection method, called supervised locally linear embedding and Spearman's rank correlation coefficient (SLLE-SC 2 ), is proposed which is based on the concept of locally linear embedding and correlation coefficient algorithms. Supervised locally linear embedding takes into account class label information and improves the classification performance. Furthermore, Spearman's rank correlation coefficient is used to remove the coexpression genes. The experiment results obtained on four public tumor microarray datasets illustrate that our method is valid and feasible.

  7. Passive Nosetip Technology (PANT) Program. Volume 17. Computer User’s Manual: Erosion Shape (EROS) Computer Code

    DTIC Science & Technology

    1974-12-01

    as a series of sections, eacN represent- ing one pressure and each preceding the corresponding pressure group of the sur- face thermochemistry deck...groups together make up the surface thermochemistry deck. Within each pressure group the transfer coefficient values will be ordered. Within each transfer...values in each pressure group may not exceed 5 but may be only 1. If no kinetics effects are to be considered a transfer coefficient of zero is acceptable

  8. Pearson's Correlation between Three Variables; Using Students' Basic Knowledge of Geometry for an Exercise in Mathematical Statistics

    ERIC Educational Resources Information Center

    Vos, Pauline

    2009-01-01

    When studying correlations, how do the three bivariate correlation coefficients between three variables relate? After transforming Pearson's correlation coefficient r into a Euclidean distance, undergraduate students can tackle this problem using their secondary school knowledge of geometry (Pythagoras' theorem and similarity of triangles).…

  9. Quantized correlation coefficient for measuring reproducibility of ChIP-chip data.

    PubMed

    Peng, Shouyong; Kuroda, Mitzi I; Park, Peter J

    2010-07-27

    Chromatin immunoprecipitation followed by microarray hybridization (ChIP-chip) is used to study protein-DNA interactions and histone modifications on a genome-scale. To ensure data quality, these experiments are usually performed in replicates, and a correlation coefficient between replicates is used often to assess reproducibility. However, the correlation coefficient can be misleading because it is affected not only by the reproducibility of the signal but also by the amount of binding signal present in the data. We develop the Quantized correlation coefficient (QCC) that is much less dependent on the amount of signal. This involves discretization of data into set of quantiles (quantization), a merging procedure to group the background probes, and recalculation of the Pearson correlation coefficient. This procedure reduces the influence of the background noise on the statistic, which then properly focuses more on the reproducibility of the signal. The performance of this procedure is tested in both simulated and real ChIP-chip data. For replicates with different levels of enrichment over background and coverage, we find that QCC reflects reproducibility more accurately and is more robust than the standard Pearson or Spearman correlation coefficients. The quantization and the merging procedure can also suggest a proper quantile threshold for separating signal from background for further analysis. To measure reproducibility of ChIP-chip data correctly, a correlation coefficient that is robust to the amount of signal present should be used. QCC is one such measure. The QCC statistic can also be applied in a variety of other contexts for measuring reproducibility, including analysis of array CGH data for DNA copy number and gene expression data.

  10. Correlation Between Geometric Similarity of Ice Shapes and the Resulting Aerodynamic Performance Degradation: A Preliminary Investigation Using WIND

    NASA Technical Reports Server (NTRS)

    Wright, William B.; Chung, James

    1999-01-01

    Aerodynamic performance calculations were performed using WIND on ten experimental ice shapes and the corresponding ten ice shapes predicted by LEWICE 2.0. The resulting data for lift coefficient and drag coefficient are presented. The difference in aerodynamic results between the experimental ice shapes and the LEWICE ice shapes were compared to the quantitative difference in ice shape geometry presented in an earlier report. Correlations were generated to determine the geometric features which have the most effect on performance degradation. Results show that maximum lift and stall angle can be correlated to the upper horn angle and the leading edge minimum thickness. Drag coefficient can be correlated to the upper horn angle and the frequency-weighted average of the Fourier coefficients. Pitching moment correlated with the upper horn angle and to a much lesser extent to the upper and lower horn thicknesses.

  11. Confidence Intervals and "F" Tests for Intraclass Correlation Coefficients Based on Three-Way Mixed Effects Models

    ERIC Educational Resources Information Center

    Zhou, Hong; Muellerleile, Paige; Ingram, Debra; Wong, Seok P.

    2011-01-01

    Intraclass correlation coefficients (ICCs) are commonly used in behavioral measurement and psychometrics when a researcher is interested in the relationship among variables of a common class. The formulas for deriving ICCs, or generalizability coefficients, vary depending on which models are specified. This article gives the equations for…

  12. Uses and Misuses of the Correlation Coefficient.

    ERIC Educational Resources Information Center

    Onwuegbuzie, Anthony J.; Daniel, Larry G.

    The purpose of this paper is to provide an in-depth critical analysis of the use and misuse of correlation coefficients. Various analytical and interpretational misconceptions are reviewed, beginning with the egregious assumption that correlational statistics may be useful in inferring causality. Additional misconceptions, stemming from…

  13. Evaluation of icing drag coefficient correlations applied to iced propeller performance prediction

    NASA Technical Reports Server (NTRS)

    Miller, Thomas L.; Shaw, R. J.; Korkan, K. D.

    1987-01-01

    Evaluation of three empirical icing drag coefficient correlations is accomplished through application to a set of propeller icing data. The various correlations represent the best means currently available for relating drag rise to various flight and atmospheric conditions for both fixed-wing and rotating airfoils, and the work presented here ilustrates and evaluates one such application of the latter case. The origins of each of the correlations are discussed, and their apparent capabilities and limitations are summarized. These correlations have been made to be an integral part of a computer code, ICEPERF, which has been designed to calculate iced propeller performance. Comparison with experimental propeller icing data shows generally good agreement, with the quality of the predicted results seen to be directly related to the radial icing extent of each case. The code's capability to properly predict thrust coefficient, power coefficient, and propeller efficiency is shown to be strongly dependent on the choice of correlation selected, as well as upon proper specificatioon of radial icing extent.

  14. Family Reintegration Experiences of Soldiers with Mild Traumatic Brain Injury

    DTIC Science & Technology

    2014-02-26

    depression scores in the spouse. Weak within-couple correlation were indicated on the other measures. Table 3 presents the Spearman correlation matrix...separately. Table 2: Spearman Correlation Coefficients for Couples Spouse MAT Spouse Depression Spouse...Anxiety Soldier MAT -0.06 Soldier Depression -0.61 Soldier Anxiety -0.12 Table 3: Spearman Correlation Coefficients for Soldiers and

  15. Correlation tests of the engine performance parameter by using the detrended cross-correlation coefficient

    NASA Astrophysics Data System (ADS)

    Dong, Keqiang; Gao, You; Jing, Liming

    2015-02-01

    The presence of cross-correlation in complex systems has long been noted and studied in a broad range of physical applications. We here focus on an aero-engine system as an example of a complex system. By applying the detrended cross-correlation (DCCA) coefficient method to aero-engine time series, we investigate the effects of the data length and the time scale on the detrended cross-correlation coefficients ρ DCCA ( T, s). We then show, for a twin-engine aircraft, that the engine fuel flow time series derived from the left engine and the right engine exhibit much stronger cross-correlations than the engine exhaust-gas temperature series derived from the left engine and the right engine do.

  16. [Mining analysis on composition and medication of menstruation prescriptions in Fu Qingzhu's Obstetrics and Gynecology].

    PubMed

    Zhu, Jia-qing; Che, Yu-xia

    2015-04-01

    In this paper, menstruation prescriptions were selected from "Fu Qingzhu's Obstetrics and Gynecology" and analyzed by using GRI algorithm, correlation analysis, hierarchical clustering method through SPSS, Clementine and traditional Chinese medicine (TCM) inheritance auxiliary systems, in order to screen out 15 menopathy prescriptions, which involve 45 traditional Chinese medicine herbs. In the study, blood-tonifying and qi-tonifying herbs were found to be frequent in the prescriptions. The most frequent single herb was white paeony root, accounting for 9.6% in the total number of prescriptions; The most frequent herb pairs were white paeony root-radix rehmanniae preparata and paeony root-angelica sinensis. Among Fu Shan's menopathy prescriptions, 61 herbal pairs showed a correlation coefficient exceeding 0.05, which evolved into 16 pairs of core combinations. The analysis showed that menopathy prescriptions in volume 1 of "Fu Qingzhu's Obstetrics and Gynecology" focused on tonic traditional Chinese medicines involving liver, spleen and kidney and were adjusted according to changes in qi, blood, cold, hot and wet, which could provide a specific reference for further studies on Fu Shan's academic thoughts and traditional Chinese medicine clinical treatment of menopathy.

  17. Spatio-temporal Variations of Characteristic Repeating Earthquake Sequences along the Middle America Trench in Mexico

    NASA Astrophysics Data System (ADS)

    Dominguez, L. A.; Taira, T.; Hjorleifsdottir, V.; Santoyo, M. A.

    2015-12-01

    Repeating earthquake sequences are sets of events that are thought to rupture the same area on the plate interface and thus provide nearly identical waveforms. We systematically analyzed seismic records from 2001 through 2014 to identify repeating earthquakes with highly correlated waveforms occurring along the subduction zone of the Cocos plate. Using the correlation coefficient (cc) and spectral coherency (coh) of the vertical components as selection criteria, we found a set of 214 sequences whose waveforms exceed cc≥95% and coh≥95%. Spatial clustering along the trench shows large variations in repeating earthquakes activity. Particularly, the rupture zone of the M8.1, 1985 earthquake shows an almost absence of characteristic repeating earthquakes, whereas the Guerrero Gap zone and the segment of the trench close to the Guerrero-Oaxaca border shows a significantly larger number of repeating earthquakes sequences. Furthermore, temporal variations associated to stress changes due to major shows episodes of unlocking and healing of the interface. Understanding the different components that control the location and recurrence time of characteristic repeating sequences is a key factor to pinpoint areas where large megathrust earthquakes may nucleate and consequently to improve the seismic hazard assessment.

  18. Prediction of Very High Reynolds Number Compressible Skin Friction

    NASA Technical Reports Server (NTRS)

    Carlson, John R.

    1998-01-01

    Flat plate skin friction calculations over a range of Mach numbers from 0.4 to 3.5 at Reynolds numbers from 16 million to 492 million using a Navier Stokes method with advanced turbulence modeling are compared with incompressible skin friction coefficient correlations. The semi-empirical correlation theories of van Driest; Cope; Winkler and Cha; and Sommer and Short T' are used to transform the predicted skin friction coefficients of solutions using two algebraic Reynolds stress turbulence models in the Navier-Stokes method PAB3D. In general, the predicted skin friction coefficients scaled well with each reference temperature theory though, overall the theory by Sommer and Short appeared to best collapse the predicted coefficients. At the lower Reynolds number 3 to 30 million, both the Girimaji and Shih, Zhu and Lumley turbulence models predicted skin-friction coefficients within 2% of the semi-empirical correlation skin friction coefficients. At the higher Reynolds numbers of 100 to 500 million, the turbulence models by Shih, Zhu and Lumley and Girimaji predicted coefficients that were 6% less and 10% greater, respectively, than the semi-empirical coefficients.

  19. A Practical Theory of Micro-Solar Power Sensor Networks

    DTIC Science & Technology

    2009-04-20

    Simulation Platform TOSSIM [LLWC03] ns-2 Matlab C++ AVRORA [TLP05] Reference Hardware Mica2 WINS, Medusa Mica Mica2, Medusa Mica2 Simulated Power Power...scale. From this raw data, we can 162 0 0.1 0.2 0.3 0.4 0.5 0.6 0.7 0.8 0.9 1 0 2 4 Correlation coefficient F re qu en cy Histogram of correlation...0.5 0.6 0.7 0.8 0.9 1 0 1 2 Correlation coefficient F re qu en cy Histogram of correlation coefficient with solar radiation measurement (Turbidity at

  20. Reliability and validity of the Chinese version of the Pediatric Quality Of Life InventoryTM (PedsQLTM) 3.0 neuromuscular module in children with Duchenne muscular dystrophy.

    PubMed

    Hu, Jun; Jiang, Li; Hong, Siqi; Cheng, Li; Kong, Min; Ye, Yuanzhen

    2013-03-15

    The Pediatric Quality of Life Inventory(TM) (PedsQL(TM)) is a widely used instrument to measure pediatric health-related quality of life (HRQOL) in children aged 2 to 18 years. The current study aimed to evaluate the reliability and validity of the Chinese version of the PedsQL(TM) 3.0 Neuromuscular Module in children with Duchenne muscular dystrophy (DMD). The PedsQL(TM) 3.0 Neuromuscular Module was translated into Chinese following PedsQL(TM) Measurement Model Translation Methodology. The Chinese version scale was administered to 56 children with DMD and their parents, and the psychometric properties were evaluated. The missing value percentages for each item of the Chinese version scale ranged from 0.00% to 0.54%. Internal consistency reliability approached or exceeded the minimum reliability standard of α = 0.7 (child α = 0.81, parent α = 0.86). Test-retest reliability was satisfactory, with intraclass correlation coefficients (ICCs) of 0.66 for children and 0.88 for parents (P < 0.01). Correlation coefficients between iteims and their hypothesized subscales were higher than those with other subscales (P < 0.05). The subscale of "About My/My Child's Neuromuscular Disease" significantly related to mobility and stair climbing status (Child t = 2.21, Parent t = 2.83, P < 0.05). The inter-correlations among the Chinese version of the PedsQL(TM) 3.0 Neuromuscular Module and the PedsQL(TM) 4.0 Generic Core Scales had medium to large effect sizes (P < 0.05). The child self-report scores were in moderate agreement with the parent proxy-report scores (ICC = 0.51, P < 0.05). The Chinese version of the PedsQLTM 3.0 Neuromuscular Module has acceptable psychometric properties. It is a reliable measure of disease-specific HRQOL in Chinese children with DMD.

  1. Detrended partial cross-correlation analysis of two nonstationary time series influenced by common external forces

    NASA Astrophysics Data System (ADS)

    Qian, Xi-Yuan; Liu, Ya-Min; Jiang, Zhi-Qiang; Podobnik, Boris; Zhou, Wei-Xing; Stanley, H. Eugene

    2015-06-01

    When common factors strongly influence two power-law cross-correlated time series recorded in complex natural or social systems, using detrended cross-correlation analysis (DCCA) without considering these common factors will bias the results. We use detrended partial cross-correlation analysis (DPXA) to uncover the intrinsic power-law cross correlations between two simultaneously recorded time series in the presence of nonstationarity after removing the effects of other time series acting as common forces. The DPXA method is a generalization of the detrended cross-correlation analysis that takes into account partial correlation analysis. We demonstrate the method by using bivariate fractional Brownian motions contaminated with a fractional Brownian motion. We find that the DPXA is able to recover the analytical cross Hurst indices, and thus the multiscale DPXA coefficients are a viable alternative to the conventional cross-correlation coefficient. We demonstrate the advantage of the DPXA coefficients over the DCCA coefficients by analyzing contaminated bivariate fractional Brownian motions. We calculate the DPXA coefficients and use them to extract the intrinsic cross correlation between crude oil and gold futures by taking into consideration the impact of the U.S. dollar index. We develop the multifractal DPXA (MF-DPXA) method in order to generalize the DPXA method and investigate multifractal time series. We analyze multifractal binomial measures masked with strong white noises and find that the MF-DPXA method quantifies the hidden multifractal nature while the multifractal DCCA method fails.

  2. The Unilateral Below Elbow Test: a function test for children with unilateral congenital below elbow deficiency.

    PubMed

    Bagley, Anita M; Molitor, Fred; Wagner, Lisa V; Tomhave, Wendy; James, Michelle A

    2006-07-01

    The Unilateral Below Elbow Test (UBET) was developed to evaluate function in bimanual activities for both the prosthesis wearer and non-wearer. Nine tasks were chosen for each of four age-specific categories defined by development stages of hand function (2-4y, 5-7y, 8-10y, and 11-21y). Two scales, Completion of Task and Method of Use, were designed to rate performance. To measure reliability, four occupational therapists scored samples of videotaped UBET performances. For Completion of Task, an interval scale, agreement in scoring was measured with interclass correlation coefficients (ICC; n=9; five females, four males). For Method of Use, a nominal scale, chance-adjusted association was calculated with Cohen's kappa coefficients (interobserver n=198; 111 females, 87 males; intraobserver n=93; 56 females, 37 males). For Completion of Task, the average ICC was 0.87 for the prosthesis-on condition, and 0.85 for the prosthesis-off condition. ICCs exceeded 0.80 for eight out of nine tasks for the two older age groups, but for only five out of nine tasks in the younger age groups. Higher inter- and intraobserver kappa coefficients for Method of Use resulted when scoring children with their prostheses on versus off. The oldest age group had lower kappa values than the other three groups. The UBET is recommended for the functional evaluation of Completion of Task in children with unilateral congenital below elbow deficiency with and without their prostheses. Method of Use scoring can evaluate individuals for directed therapy interventions or prosthetic training.

  3. Ensemble Solute Transport in 2-D Operator-Stable Random Fields

    NASA Astrophysics Data System (ADS)

    Monnig, N. D.; Benson, D. A.

    2006-12-01

    The heterogeneous velocity field that exists at many scales in an aquifer will typically cause a dissolved solute plume to grow at a rate faster than Fick's Law predicts. Some statistical model must be adopted to account for the aquifer structure that engenders the velocity heterogeneity. A fractional Brownian motion (fBm) model has been shown to create the long-range correlation that can produce continually faster-than-Fickian plume growth. Previous fBm models have assumed isotropic scaling (defined here by a scalar Hurst coefficient). Motivated by field measurements of aquifer hydraulic conductivity, recent techniques were developed to construct random fields with anisotropic scaling with a self-similarity parameter that is defined by a matrix. The growth of ensemble plumes is analyzed for transport through 2-D "operator- stable" fBm hydraulic conductivity (K) fields. Both the longitudinal and transverse Hurst coefficients are important to both plume growth rates and the timing and duration of breakthrough. Smaller Hurst coefficients in the transverse direction lead to more "continuity" or stratification in the direction of transport. The result is continually faster-than-Fickian growth rates, highly non-Gaussian ensemble plumes, and a longer tail early in the breakthrough curve. Contrary to some analytic stochastic theories for monofractal K fields, the plume growth rate never exceeds Mercado's [1967] purely stratified aquifer growth rate of plume apparent dispersivity proportional to mean distance. Apparent super-Mercado growth must be the result of other factors, such as larger plumes corresponding to either a larger initial plume size or greater variance of the ln(K) field.

  4. Repeatability of chemical-shift-encoded water-fat MRI and diffusion-tensor imaging in lower extremity muscles in children.

    PubMed

    Ponrartana, Skorn; Andrade, Kristine E; Wren, Tishya A L; Ramos-Platt, Leigh; Hu, Houchun H; Bluml, Stefan; Gilsanz, Vicente

    2014-06-01

    The purpose of this study was to assess the repeatability of water-fat MRI and diffusion-tensor imaging (DTI) as quantitative biomarkers of pediatric lower extremity skeletal muscle. MRI at 3 T of a randomly selected thigh and lower leg of seven healthy children was studied using water-fat separation and DTI techniques. Muscle-fat fraction, apparent diffusion coefficient (ADC), and fractional anisotropy (FA) values were calculated. Test-retest and interrater repeatability were assessed by calculating the Pearson correlation coefficient, intraclass correlation coefficient, and Bland-Altman analysis. Bland-Altman plots show that the mean difference between test-retest and interrater measurements of muscle-fat fraction, ADC, and FA was near 0. The correlation coefficients and intraclass correlation coefficients were all between 0.88 and 0.99 (p < 0.05), suggesting excellent reliability of the measurements. Muscle-fat fraction measurements from water-fat MRI exhibited the highest intraclass correlation coefficient. Interrater agreement was consistently better than test-retest comparisons. Water-fat MRI and DTI measurements in lower extremity skeletal muscles are objective repeatable biomarkers in children. This knowledge should aid in the understanding of the number of participants needed in clinical trials when using these determinations as an outcome measure to noninvasively monitor neuromuscular disease.

  5. Observations of copolar correlation coefficient through a bright band at vertical incidence

    NASA Technical Reports Server (NTRS)

    Zrnic, D. S.; Raghavan, R.; Chandrasekar, V.

    1994-01-01

    This paper discusses an application of polarimetric measurements at vertical incidence. In particular, the correlation coefficients between linear copolar components are examined, and measurements obtained with the National Severe Storms Laboratory (NSSL)'s and National Center for Atmospheric Research (NCAR)'s polarimetric radars are presented. The data are from two well-defined bright bands. A sharp decrease of the correlation coefficient, confined to a height interval of a few hundred meters, marks the bottom of the bright band.

  6. Relationship of body mass index to percent body fat and waist circumference among schoolchildren in Japan--the influence of gender and obesity: a population-based cross-sectional study.

    PubMed

    Ochiai, Hirotaka; Shirasawa, Takako; Nishimura, Rimei; Morimoto, Aya; Shimada, Naoki; Ohtsu, Tadahiro; Kujirai, Emiko; Hoshino, Hiromi; Tajima, Naoko; Kokaze, Akatsuki

    2010-08-18

    Although the correlation coefficient between body mass index (BMI) and percent body fat (%BF) or waist circumference (WC) has been reported, studies conducted among population-based schoolchildren to date have been limited in Japan, where %BF and WC are not usually measured in annual health examinations at elementary schools or junior high schools. The aim of the present study was to investigate the relationship of BMI to %BF and WC and to examine the influence of gender and obesity on these relationships among Japanese schoolchildren. Subjects included 3,750 schoolchildren from the fourth and seventh grade in Ina-town, Saitama Prefecture, Japan between 2004 and 2008. Information about subject's age, sex, height, weight, %BF, and WC was collected from annual physical examinations. %BF was measured with a bipedal biometrical impedance analysis device. Obesity was defined by the following two criteria: the obese definition of the Centers for Disease Control and Prevention, and the definition of obesity for Japanese children. Pearson's correlation coefficients between BMI and %BF or WC were calculated separately for sex. Among fourth graders, the correlation coefficients between BMI and %BF were 0.74 for boys and 0.97 for girls, whereas those between BMI and WC were 0.94 for boys and 0.90 for girls. Similar results were observed in the analysis of seventh graders. The correlation coefficient between BMI and %BF varied by physique (obese or non-obese), with weaker correlations among the obese regardless of the definition of obesity; most correlation coefficients among obese boys were less than 0.5, whereas most correlations among obese girls were more than 0.7. On the other hand, the correlation coefficients between BMI and WC were more than 0.8 among boys and almost all coefficients were more than 0.7 among girls, regardless of physique. BMI was positively correlated with %BF and WC among Japanese schoolchildren. The correlations could be influenced by obesity as well as by gender. Accordingly, it is essential to consider gender and obesity when using BMI as a surrogate for %BF and WC for epidemiological use.

  7. A Method for Approximating the Bivariate Normal Correlation Coefficient.

    ERIC Educational Resources Information Center

    Kirk, David B.

    Improvements of the Gaussian quadrature in conjunction with the Newton-Raphson iteration technique (TM 000 789) are discussed as effective methods of calculating the bivariate normal correlation coefficient. (CK)

  8. Semi-quantitative spectrographic analysis and rank correlation in geochemistry

    USGS Publications Warehouse

    Flanagan, F.J.

    1957-01-01

    The rank correlation coefficient, rs, which involves less computation than the product-moment correlation coefficient, r, can be used to indicate the degree of relationship between two elements. The method is applicable in situations where the assumptions underlying normal distribution correlation theory may not be satisfied. Semi-quantitative spectrographic analyses which are reported as grouped or partly ranked data can be used to calculate rank correlations between elements. ?? 1957.

  9. Effect of inhibitory feedback on correlated firing of spiking neural network.

    PubMed

    Xie, Jinli; Wang, Zhijie

    2013-08-01

    Understanding the properties and mechanisms that generate different forms of correlation is critical for determining their role in cortical processing. Researches on retina, visual cortex, sensory cortex, and computational model have suggested that fast correlation with high temporal precision appears consistent with common input, and correlation on a slow time scale likely involves feedback. Based on feedback spiking neural network model, we investigate the role of inhibitory feedback in shaping correlations on a time scale of 100 ms. Notably, the relationship between the correlation coefficient and inhibitory feedback strength is non-monotonic. Further, computational simulations show how firing rate and oscillatory activity form the basis of the mechanisms underlying this relationship. When the mean firing rate holds unvaried, the correlation coefficient increases monotonically with inhibitory feedback, but the correlation coefficient keeps decreasing when the network has no oscillatory activity. Our findings reveal that two opposing effects of the inhibitory feedback on the firing activity of the network contribute to the non-monotonic relationship between the correlation coefficient and the strength of the inhibitory feedback. The inhibitory feedback affects the correlated firing activity by modulating the intensity and regularity of the spike trains. Finally, the non-monotonic relationship is replicated with varying transmission delay and different spatial network structure, demonstrating the universality of the results.

  10. Robust Approximations to the Non-Null Distribution of the Product Moment Correlation Coefficient I: The Phi Coefficient.

    ERIC Educational Resources Information Center

    Edwards, Lynne K.; Meyers, Sarah A.

    Correlation coefficients are frequently reported in educational and psychological research. The robustness properties and optimality among practical approximations when phi does not equal 0 with moderate sample sizes are not well documented. Three major approximations and their variations are examined: (1) a normal approximation of Fisher's Z,…

  11. Correcting Coefficient Alpha for Correlated Errors: Is [alpha][K]a Lower Bound to Reliability?

    ERIC Educational Resources Information Center

    Rae, Gordon

    2006-01-01

    When errors of measurement are positively correlated, coefficient alpha may overestimate the "true" reliability of a composite. To reduce this inflation bias, Komaroff (1997) has proposed an adjusted alpha coefficient, ak. This article shows that ak is only guaranteed to be a lower bound to reliability if the latter does not include correlated…

  12. Prediction of stream volatilization coefficients

    USGS Publications Warehouse

    Rathbun, Ronald E.

    1990-01-01

    Equations are developed for predicting the liquid-film and gas-film reference-substance parameters for quantifying volatilization of organic solutes from streams. Molecular weight and molecular-diffusion coefficients of the solute are used as correlating parameters. Equations for predicting molecular-diffusion coefficients of organic solutes in water and air are developed, with molecular weight and molal volume as parameters. Mean absolute errors of prediction for diffusion coefficients in water are 9.97% for the molecular-weight equation, 6.45% for the molal-volume equation. The mean absolute error for the diffusion coefficient in air is 5.79% for the molal-volume equation. Molecular weight is not a satisfactory correlating parameter for diffusion in air because two equations are necessary to describe the values in the data set. The best predictive equation for the liquid-film reference-substance parameter has a mean absolute error of 5.74%, with molal volume as the correlating parameter. The best equation for the gas-film parameter has a mean absolute error of 7.80%, with molecular weight as the correlating parameter.

  13. Divergence of actual and reference evapotranspiration observations for irrigated sugarcane with windy tropical conditions

    NASA Astrophysics Data System (ADS)

    Anderson, R. G.; Wang, D.; Tirado-Corbalá, R.; Zhang, H.; Ayars, J. E.

    2015-01-01

    Standardized reference evapotranspiration (ET) and ecosystem-specific vegetation coefficients are frequently used to estimate actual ET. However, equations for calculating reference ET have not been well validated in tropical environments. We measured ET (ETEC) using eddy covariance (EC) towers at two irrigated sugarcane fields on the leeward (dry) side of Maui, Hawaii, USA in contrasting climates. We calculated reference ET at the fields using the short (ET0) and tall (ETr) vegetation versions of the American Society for Civil Engineers (ASCE) equation. The ASCE equations were compared to the Priestley-Taylor ET (ETPT) and ETEC. Reference ET from the ASCE approaches exceeded ETEC during the mid-period (when vegetation coefficients suggest ETEC should exceed reference ET). At the windier tower site, cumulative ETr exceeded ETEC by 854 mm over the course of the mid-period (267 days). At the less windy site, mid-period ETr still exceeded ETEC, but the difference was smaller (443 mm). At both sites, ETPT approximated mid-period ETEC more closely than the ASCE equations ((ETPT-ETEC) < 170 mm). Analysis of applied water and precipitation, soil moisture, leaf stomatal resistance, and canopy cover suggest that the lower observed ETEC was not the result of water stress or reduced vegetation cover. Use of a custom-calibrated bulk canopy resistance improved the reference ET estimate and reduced seasonal ET discrepancy relative to ETPT and ETEC in the less windy field and had mixed performance in the windier field. These divergences suggest that modifications to reference ET equations may be warranted in some tropical regions.

  14. Divergence of reference evapotranspiration observations with windy tropical conditions

    NASA Astrophysics Data System (ADS)

    Anderson, R. G.; Wang, D.; Tirado-Corbalá, R.; Zhang, H.; Ayars, J. E.

    2014-06-01

    Standardized reference evapotranspiration (ET) and ecosystem-specific vegetation coefficients are frequently used to estimate actual ET. However, equations for calculating reference ET have not been well validated in tropical environments. We measured ET (ETEC) using Eddy Covariance (EC) towers at two irrigated sugarcane fields on the leeward (dry) side of Maui, Hawaii, USA in contrasting climates. We calculated reference ET at the fields using the short (ET0) and tall (ETr) vegetation versions of the American Society for Civil Engineers (ASCE) equation. The ASCE equations were compared to the Priestley-Taylor ET (ETPT) and ETEC. Reference ET from the ASCE approaches exceeded ETEC during the mid-period (when vegetation coefficients suggest ETEC should exceed reference ET). At the windier tower site, cumulative ETr exceeded ETEC by 854 mm over the course of the mid-period (267 days). At the less windy site, mid-period ETr still exceeded ETEC, but the difference was smaller (443 mm). At both sites, ETPT approximated mid-period ETEC more closely than the ASCE equations ((ETPT-ETEC) < 170 mm). Analysis of applied water and precipitation, soil moisture, leaf stomatal resistance, and canopy cover suggest that the lower observed ETEC was not the result of water stress or reduced vegetation cover. Use of a custom calibrated bulk canopy resistance improved the reference ET estimate and reduced seasonal ET discrepancy relative to ETPT and ETEC for the less windy field and had mixed performance at the windier field. These divergences suggest that modifications to reference ET equations may be warranted in some tropical regions.

  15. Python Waveform Cross-Correlation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Templeton, Dennise

    PyWCC is a tool to compute seismic waveform cross-correlation coefficients on single-component or multiple-component seismic data across a network of seismic sensors. PyWCC compares waveform data templates with continuous seismic data, associates the resulting detections, identifies the template with the highest cross-correlation coefficient, and outputs a catalog of detections above a user-defined absolute cross-correlation threshold value.

  16. Hadamard multimode optical imaging transceiver

    DOEpatents

    Cooke, Bradly J; Guenther, David C; Tiee, Joe J; Kellum, Mervyn J; Olivas, Nicholas L; Weisse-Bernstein, Nina R; Judd, Stephen L; Braun, Thomas R

    2012-10-30

    Disclosed is a method and system for simultaneously acquiring and producing results for multiple image modes using a common sensor without optical filtering, scanning, or other moving parts. The system and method utilize the Walsh-Hadamard correlation detection process (e.g., functions/matrix) to provide an all-binary structure that permits seamless bridging between analog and digital domains. An embodiment may capture an incoming optical signal at an optical aperture, convert the optical signal to an electrical signal, pass the electrical signal through a Low-Noise Amplifier (LNA) to create an LNA signal, pass the LNA signal through one or more correlators where each correlator has a corresponding Walsh-Hadamard (WH) binary basis function, calculate a correlation output coefficient for each correlator as a function of the corresponding WH binary basis function in accordance with Walsh-Hadamard mathematical principles, digitize each of the correlation output coefficient by passing each correlation output coefficient through an Analog-to-Digital Converter (ADC), and performing image mode processing on the digitized correlation output coefficients as desired to produce one or more image modes. Some, but not all, potential image modes include: multi-channel access, temporal, range, three-dimensional, and synthetic aperture.

  17. [Habitat suitability index of larval Japanese Halfbeak (Hyporhamphus sajori) in Bohai Sea based on geographically weighted regression.

    PubMed

    Zhao, Yang; Zhang, Xue Qing; Bian, Xiao Dong

    2018-01-01

    To investigate the early supplementary processes of fishre sources in the Bohai Sea, the geographically weighted regression (GWR) was introduced to the habitat suitability index (HSI) model. The Bohai Sea larval Japanese Halfbeak HSI GWR model was established with four environmental variables, including sea surface temperature (SST), sea surface salinity (SSS), water depth (DEP), and chlorophyll a concentration (Chl a). Results of the simulation showed that the four variables had different performances in August 2015. SST and Chl a were global variables, and had little impacts on HSI, with the regression coefficients of -0.027 and 0.006, respectively. SSS and DEP were local variables, and had larger impacts on HSI, while the average values of absolute values of their regression coefficients were 0.075 and 0.129, respectively. In the central Bohai Sea, SSS showed a negative correlation with HSI, and the most negative correlation coefficient was -0.3. In contrast, SSS was correlated positively but weakly with HSI in the three bays of Bohai Sea, and the largest correlation coefficient was 0.1. In particular, DEP and HSI were negatively correlated in the entire Bohai Sea, while they were more negatively correlated in the three bays of Bohai than in the central Bohai Sea, and the most negative correlation coefficient was -0.16 in the three bays. The Poisson regression coefficient of the HSI GWR model was 0.705, consistent with field measurements. Therefore, it could provide a new method for the research on fish habitats in the future.

  18. Psychometric properties of the modified RESIDE physical activity questionnaire among low-income overweight women.

    PubMed

    Jones, Sydney A; Evenson, Kelly R; Johnston, Larry F; Trost, Stewart G; Samuel-Hodge, Carmen; Jewell, David A; Kraschnewski, Jennifer L; Keyserling, Thomas C

    2015-01-01

    This study explored the criterion-related validity and test-retest reliability of the modified RESIDential Environment physical activity questionnaire and whether the instrument's validity varied by body mass index, education, race/ethnicity, or employment status. Validation study using baseline data collected for randomized trial of a weight loss intervention. Participants recruited from health departments wore an ActiGraph accelerometer and self-reported non-occupational walking, moderate and vigorous physical activity on the modified RESIDential Environment questionnaire. We assessed validity (n=152) using Spearman correlation coefficients, and reliability (n=57) using intraclass correlation coefficients. When compared to steps, moderate physical activity, and bouts of moderate/vigorous physical activity measured by accelerometer, these questionnaire measures showed fair evidence for validity: recreational walking (Spearman correlation coefficients 0.23-0.36), total walking (Spearman correlation coefficients 0.24-0.37), and total moderate physical activity (Spearman correlation coefficients 0.18-0.36). Correlations for self-reported walking and moderate physical activity were higher among unemployed participants and women with lower body mass indices. Generally no other variability in the validity of the instrument was found. Evidence for reliability of RESIDential Environment measures of recreational walking, total walking, and total moderate physical activity was substantial (intraclass correlation coefficients 0.56-0.68). Evidence for questionnaire validity and reliability varied by activity domain and was strongest for walking measures. The questionnaire may capture physical activity less accurately among women with higher body mass indices and employed participants. Capturing occupational activity, specifically walking at work, may improve questionnaire validity. Copyright © 2014 Sports Medicine Australia. Published by Elsevier Ltd. All rights reserved.

  19. Nonlinearity of the forward-backward correlation function in the model with string fusion

    NASA Astrophysics Data System (ADS)

    Vechernin, Vladimir

    2017-12-01

    The behavior of the forward-backward correlation functions and the corresponding correlation coefficients between multiplicities and transverse momenta of particles produced in high energy hadronic interactions is analyzed by analytical and MC calculations in the models with and without string fusion. The string fusion is taking into account in simplified form by introducing the lattice in the transverse plane. The results obtained with two alternative definitions of the forward-backward correlation coefficient are compared. It is shown that the nonlinearity of correlation functions increases with the width of observation windows, leading at small string density to a strong dependence of correlation coefficient value on the definition. The results of the modeling enable qualitatively to explain the experimentally observed features in the behavior of the correlation functions between multiplicities and mean transverse momenta at small and large multiplicities.

  20. The relationship between the managerial skills and results of "performance evaluation "tool among nursing managers in teaching hospitals of Iran University of Medical Science.

    PubMed

    Isfahani, Haleh Mousavi; Aryankhesal, Aidin; Haghani, Hamid

    2014-09-25

    Performance of different organizations, such as hospitals is mainly influenced by their managers' performance. Nursing managers have an important role in hospital performance and their managerial skills can improve the quality of the services. Hence, the present study was conducted in order to assess the relationship between the managerial skills and the results of their performance evaluation in Teaching Hospitals of Iran University of Medical Science in 2013. The research used the cross sectional method in 2013. It was done by distributing a managerial skills assessment questionnaire, with close-ended questions in 5 choice Likert scale, among 181 managers and head nurses of hospitals of Iran university of Medical Sciences; among which 131 answered the questions. Another data collection tools was a forms to record evaluation marks from the personnel records. We used Pearson and Spearman correlation tests and SPSS for analysis and description (frequency, mean and standard deviation). Results showed that the managerial skills of the nursing mangers were fair (2.57 out of 5) and the results of the performance evaluation were in a good condition (98.44). The mangers' evaluation results and the managerial skills scores were not in a meaningful correlation (r=0.047 np=0.856). The research showed no correlation between different domains of managerial skills and the performance evaluation marks: decision making skills (r=0.074 and p=0.399), leadership (correlation coefficient 0.028 and p=0.654), motivation (correlation coefficient 0.118 and p=0.163), communication  (correlation coefficient 0.116 and p=0.122), systematic thinking  (correlation coefficient 0.028 and p=0.828), time management (correlation coefficient 0.077 and p=0.401) and strategic thinking  (correlation coefficient 0.041 and p=0.756). Lack of any correlation and relation between managers' managerial skills and their performance evaluation results shows need to a fundamental revision at managers' performance evaluation form.

  1. Spatial and temporal agreement in climate model simulations of the Interdecadal Pacific Oscillation

    DOE PAGES

    Henley, Benjamin J.; Meehl, Gerald; Power, Scott B.; ...

    2017-01-31

    Accelerated warming and hiatus periods in the long-term rise of Global Mean Surface Temperature (GMST) have, in recent decades, been associated with the Interdecadal Pacific Oscillation (IPO). Critically, decadal climate prediction relies on the skill of state-of-the-art climate models to reliably represent these low-frequency climate variations. We undertake a systematic evaluation of the simulation of the IPO in the suite of Coupled Model Intercomparison Project 5 (CMIP5) models. We track the IPO in pre-industrial (control) and all-forcings (historical) experiments using the IPO tripole index (TPI). The TPI is explicitly aligned with the observed spatial pattern of the IPO, and circumventsmore » assumptions about the nature of global warming. We find that many models underestimate the ratio of decadal-to-total variance in sea surface temperatures (SSTs). However, the basin-wide spatial pattern of positive and negative phases of the IPO are simulated reasonably well, with spatial pattern correlation coefficients between observations and models spanning the range 0.4–0.8. Deficiencies are mainly in the extratropical Pacific. Models that better capture the spatial pattern of the IPO also tend to more realistically simulate the ratio of decadal to total variance. Of the 13% of model centuries that have a fractional bias in the decadal-to-total TPI variance of 0.2 or less, 84% also have a spatial pattern correlation coefficient with the observed pattern exceeding 0.5. This result is highly consistent across both IPO positive and negative phases. This is evidence that the IPO is related to one or more inherent dynamical mechanisms of the climate system.« less

  2. Spatial and temporal agreement in climate model simulations of the Interdecadal Pacific Oscillation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Henley, Benjamin J.; Meehl, Gerald; Power, Scott B.

    Accelerated warming and hiatus periods in the long-term rise of Global Mean Surface Temperature (GMST) have, in recent decades, been associated with the Interdecadal Pacific Oscillation (IPO). Critically, decadal climate prediction relies on the skill of state-of-the-art climate models to reliably represent these low-frequency climate variations. We undertake a systematic evaluation of the simulation of the IPO in the suite of Coupled Model Intercomparison Project 5 (CMIP5) models. We track the IPO in pre-industrial (control) and all-forcings (historical) experiments using the IPO tripole index (TPI). The TPI is explicitly aligned with the observed spatial pattern of the IPO, and circumventsmore » assumptions about the nature of global warming. We find that many models underestimate the ratio of decadal-to-total variance in sea surface temperatures (SSTs). However, the basin-wide spatial pattern of positive and negative phases of the IPO are simulated reasonably well, with spatial pattern correlation coefficients between observations and models spanning the range 0.4–0.8. Deficiencies are mainly in the extratropical Pacific. Models that better capture the spatial pattern of the IPO also tend to more realistically simulate the ratio of decadal to total variance. Of the 13% of model centuries that have a fractional bias in the decadal-to-total TPI variance of 0.2 or less, 84% also have a spatial pattern correlation coefficient with the observed pattern exceeding 0.5. This result is highly consistent across both IPO positive and negative phases. This is evidence that the IPO is related to one or more inherent dynamical mechanisms of the climate system.« less

  3. Quantitative Analysis of Heavy Metals in Water Based on LIBS with an Automatic Device for Sample Preparation

    NASA Astrophysics Data System (ADS)

    Hu, Li; Zhao, Nanjing; Liu, Wenqing; Meng, Deshuo; Fang, Li; Wang, Yin; Yu, Yang; Ma, Mingjun

    2015-08-01

    Heavy metals in water can be deposited on graphite flakes, which can be used as an enrichment method for laser-induced breakdown spectroscopy (LIBS) and is studied in this paper. The graphite samples were prepared with an automatic device, which was composed of a loading and unloading module, a quantitatively adding solution module, a rapid heating and drying module and a precise rotating module. The experimental results showed that the sample preparation methods had no significant effect on sample distribution and the LIBS signal accumulated in 20 pulses was stable and repeatable. With an increasing amount of the sample solution on the graphite flake, the peak intensity at Cu I 324.75 nm accorded with the exponential function with a correlation coefficient of 0.9963 and the background intensity remained unchanged. The limit of detection (LOD) was calculated through linear fitting of the peak intensity versus the concentration. The LOD decreased rapidly with an increasing amount of sample solution until the amount exceeded 20 mL and the correlation coefficient of exponential function fitting was 0.991. The LOD of Pb, Ni, Cd, Cr and Zn after evaporating different amounts of sample solution on the graphite flakes was measured and the variation tendency of their LOD with sample solution amounts was similar to the tendency for Cu. The experimental data and conclusions could provide a reference for automatic sample preparation and heavy metal in situ detection. supported by National Natural Science Foundation of China (No. 60908018), National High Technology Research and Development Program of China (No. 2013AA065502) and Anhui Province Outstanding Youth Science Fund of China (No. 1108085J19)

  4. Development and validation of a new instrument to measure health-related quality of life in patients with psoriatic arthritis: the VITACORA-19.

    PubMed

    Torre-Alonso, Juan Carlos; Gratacós, Jordi; Rey-Rey, José Santos; Valdazo de Diego, Juan Pablo; Urriticoechea-Arana, Ana; Daudén, Esteban; Moreno, Mireia; Zarco-Montejo, Pedro; Collantes-Estévez, Eduardo; Fernández-López, Juan Antonio

    2014-10-01

    To develop/validate an instrument to measure health-related quality of life (HRQoL) in patients with psoriatic arthritis (PsA), for use in clinical studies. An item pool of 35 items was generated following standardized procedures. Item reduction was performed using clinimetric and psychometric approaches after administration to 66 patients with PsA. The resulting instrument, the VITACORA-19, consists of 19 items. Its validity content, internal consistency, test-retest reliability, known groups/convergent validity, and sensitivity to change were tested in a longitudinal and multicenter study conducted in 10 hospitals in Spain, with 323 patients who also completed the EuroQol 5-dimensional questionnaire (EQ-5D) and a health status transition item. There were 3 study groups: group A (n = 209, patients with PsA), group B (n = 71, patients with arthritis without psoriatic aspect, patients with arthrosis, and patients with dermatitis), and group C (n = 43, healthy controls). The questionnaire was considered easy/very easy to answer by 94.7% of the patients with PsA. The factorial analysis clearly identified only 1 factor. Cronbach's alpha coefficient and interclass correlation coefficients exceeded 0.90. Statistically significant differences (p < 0.001) were observed between groups: subjects from group C had better HRQoL, followed by group B, and finally group A had the worst HRQoL. The VITACORA-19 scores showed significant correlations (p < 0.001) to PsA disease activity, EQ-5D, and perceived health state, scoring the patients with better health state higher. The minimum important difference was established as an 8-point change in the global score. The Spanish-developed VITACORA-19, designed to measure HRQoL in patients with PsA, has good validity, reliability, and sensitivity to change.

  5. Utility of a near real-time emergency department syndromic surveillance system to track injuries in New York City.

    PubMed

    Seil, Kacie; Marcum, Jennifer; Lall, Ramona; Stayton, Catherine

    2015-12-01

    The New York City emergency department (ED) syndromic surveillance (SS) system provides near real-time data on the majority of ED visits. The utility of ED SS for injury surveillance has not been thoroughly evaluated. We created injury syndromes based on ED chief complaint information and evaluated their utility compared to administrative billing data. Six injury syndromes were developed: traffic-related injuries to pedal cyclists, pedestrians, and motor vehicle occupants; fall-related injuries; firearm-related injuries; and assault-related stabbings. Daily injury counts were compared for ED SS and the administrative billing data for years 2008-2010. We examined characteristics of injury trends and patterns between the two systems, calculating descriptive statistics for temporal patterns and Pearson correlation coefficients (r) for temporal trends. We also calculated proportions of demographic and geospatial patterns for both systems. Although daily volume of the injuries varied between the two systems, the temporal patterns were similar (all r values for daily volume exceeded 0.65). Comparisons of injuries by time of day, day of week, and quarter of year demonstrated high agreement between the two systems-the majority had an absolute percentage point difference of 2.0 or less. Distributions of injury by sex and age group also aligned well. Distribution of injury by neighborhood of residence showed mixed results-some neighborhood comparisons showed a high level of agreement between systems, while others were less successful. As evidenced by the strong positive correlation coefficients and the small absolute percentage point differences in our comparisons, we conclude that ED SS captures temporal trends and patterns of injury-related ED visits effectively. The system could be used to identify changes in injury patterns, allowing for situational awareness during emergencies, timely response, and public messaging.

  6. Preliminary estimate of possible flood elevations in the Columbia River at Trojan Nuclear Power Plant due to failure of debris dam blocking Spirit Lake, Washington

    USGS Publications Warehouse

    Kresch, D.L.; Laenen, Antonius

    1984-01-01

    Failure of the debris dam, blocking the outflow of Spirit Lake near Mount St. Helens, could result in a mudflow down the Toutle and Cowlitz Rivers into the Columbia River. Flood elevations at the Trojan Nuclear Power Plant on the Columbia River, 5 mi upstream from the Cowlitz River, were simulated with a hydraulic routing model. The simulations are made for four Columbia River discharges in each of two scenarios, one in which Columbia River floods coincide with a mudflow and the other in which Columbia River floods follow a mudflow sediment deposit upstream from the Cowlitz River. In the first scenario, Manning 's roughness coefficients for clear water and for mudflow in the Columbia River are used; in the second scenario only clear water coefficients are used. The grade elevation at the power plant is 45 ft above sea level. The simulated elevations exceed 44 ft if the mudflow coincides with a Columbia River discharge that has a recurrence interval greater than 10 years (610,000 cu ft/sec); the mudflow is assumed to extend downstream from the Cowlitz River to the mouth of the Columbia River, and Manning 's roughness coefficients for a mudflow are used. The simulated elevation is 32 ft if the mudflow coincides with a 100-yr flood (820,000 cu ft/sec) and clear-water Manning 's coefficients are used throughout the entire reach of the Columbia River. The elevations exceed 45 ft if a flow exceeding the 2-yr peak discharge in the Columbia River (410,000 cu ft/sec) follows the deposit of 0.5 billion cu yd of mudflow sediment upstream of the Cowlitz River before there has been any appreciable scour or dredging of the deposit. In this simulation it is assumed that: (1) the top of the sediment deposited in the Columbia River is at an elevation of 30 ft at the mouth of the Cowlitz River, (2) the surface elevation of the sediment deposit decreases in an upstream direction at a rate of 2.5 ft/mi, and (3) clear water Manning 's coefficients apply to the entire modeled reach of the Columbia River. (Author 's abstract)

  7. Pulmonary Catherization Data Correlate Poorly with Renal Function in Heart Failure.

    PubMed

    Masha, Luke; Stone, James; Stone, Danielle; Zhang, Jun; Sheng, Luo

    2018-04-10

    The mechanisms of renal dysfunction in heart failure are poorly understood. We chose to explore the relationship of cardiac filling pressures and cardiac index (CI) in relation to renal dysfunction in advanced heart failure. To determine the relationship between renal function and cardiac filling pressures using the United Network of Organ Sharing (UNOS) pulmonary artery catherization registry. Patients over the age of 18 years who were listed for single-organ heart transplantation were included. Exclusion criteria included a history of mechanical circulatory support, previous transplantation, any use of renal replacement therapy, prior history of malignancy, and cardiac surgery, amongst others. Correlations between serum creatinine (SCr) and CI, pulmonary capillary wedge pressure (PCWP), pulmonary artery systolic pressure (PASP), and pulmonary artery diastolic pressure (PADP) were assessed by Pearson correlation coefficients and simple linear regression coefficients. Pearson correlation coefficients between SCr and PCWP, PASP, and PADP were near zero with values of 0.1, 0.07, and 0.08, respectively (p < 0.0001). A weak negative correlation coefficient between SCr and CI was found (correlation coefficient, -0.045, p = 0.027). In a subgroup of young patients unlikely to have noncardiac etiologies, no significant correlations between these values were identified. These findings suggest that, as assessed by pulmonary artery catherization, none of the factors - PCWP, PASP, PADP, or CI - play a prominent role in cardiorenal syndromes. © 2018 S. Karger AG, Basel.

  8. Apparent Diffusion Coefficient and Dynamic Contrast-Enhanced Magnetic Resonance Imaging in Pancreatic Cancer: Characteristics and Correlation With Histopathologic Parameters.

    PubMed

    Ma, Wanling; Li, Na; Zhao, Weiwei; Ren, Jing; Wei, Mengqi; Yang, Yong; Wang, Yingmei; Fu, Xin; Zhang, Zhuoli; Larson, Andrew C; Huan, Yi

    2016-01-01

    To clarify diffusion and perfusion abnormalities and evaluate correlation between apparent diffusion coefficient (ADC), MR perfusion and histopathologic parameters of pancreatic cancer (PC). Eighteen patients with PC underwent diffusion-weighted imaging and dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI). Parameters of DCE-MRI and ADC of cancer and non-cancerous tissue were compared. Correlation between the rate constant that represents transfer of contrast agent from the arterial blood into the extravascular extracellular space (K, volume of the extravascular extracellular space per unit volume of tissue (Ve), and ADC of PC and histopathologic parameters were analyzed. The rate constant that represents transfer of contrast agent from the extravascular extracellular space into blood plasma, K, tissue volume fraction occupied by vascular space, and ADC of PC were significantly lower than nontumoral pancreases. Ve of PC was significantly higher than that of nontumoral pancreas. Apparent diffusion coefficient and K values of PC were negatively correlated to fibrosis content and fibroblast activation protein staining score. Fibrosis content was positively correlated to Ve. Apparent diffusion coefficient values and parameters of DCE-MRI can differentiate PC from nontumoral pancreases. There are correlations between ADC, K, Ve, and fibrosis content of PC. Fibroblast activation protein staining score of PC is negatively correlated to ADC and K. Apparent diffusion coefficient, K, and Ve may be feasible to predict prognosis of PC.

  9. A comparison of two indices for the intraclass correlation coefficient.

    PubMed

    Shieh, Gwowen

    2012-12-01

    In the present study, we examined the behavior of two indices for measuring the intraclass correlation in the one-way random effects model: the prevailing ICC(1) (Fisher, 1938) and the corrected eta-squared (Bliese & Halverson, 1998). These two procedures differ both in their methods of estimating the variance components that define the intraclass correlation coefficient and in their performance of bias and mean squared error in the estimation of the intraclass correlation coefficient. In contrast with the natural unbiased principle used to construct ICC(1), in the present study it was analytically shown that the corrected eta-squared estimator is identical to the maximum likelihood estimator and the pairwise estimator under equal group sizes. Moreover, the empirical results obtained from the present Monte Carlo simulation study across various group structures revealed the mutual dominance relationship between their truncated versions for negative values. The corrected eta-squared estimator performs better than the ICC(1) estimator when the underlying population intraclass correlation coefficient is small. Conversely, ICC(1) has a clear advantage over the corrected eta-squared for medium and large magnitudes of population intraclass correlation coefficient. The conceptual description and numerical investigation provide guidelines to help researchers choose between the two indices for more accurate reliability analysis in multilevel research.

  10. Statistical characteristics of cloud variability. Part 1: Retrieved cloud liquid water path at three ARM sites

    NASA Astrophysics Data System (ADS)

    Huang, Dong; Campos, Edwin; Liu, Yangang

    2014-09-01

    Statistical characteristics of cloud variability are examined for their dependence on averaging scales and best representation of probability density function with the decade-long retrieval products of cloud liquid water path (LWP) from the tropical western Pacific (TWP), Southern Great Plains (SGP), and North Slope of Alaska (NSA) sites of the Department of Energy's Atmospheric Radiation Measurement Program. The statistical moments of LWP show some seasonal variation at the SGP and NSA sites but not much at the TWP site. It is found that the standard deviation, relative dispersion (the ratio of the standard deviation to the mean), and skewness all quickly increase with the averaging window size when the window size is small and become more or less flat when the window size exceeds 12 h. On average, the cloud LWP at the TWP site has the largest values of standard deviation, relative dispersion, and skewness, whereas the NSA site exhibits the least. Correlation analysis shows that there is a positive correlation between the mean LWP and the standard deviation. The skewness is found to be closely related to the relative dispersion with a correlation coefficient of 0.6. The comparison further shows that the lognormal, Weibull, and gamma distributions reasonably explain the observed relationship between skewness and relative dispersion over a wide range of scales.

  11. Statistical characteristics of cloud variability. Part 1: Retrieved cloud liquid water path at three ARM sites: Observed cloud variability at ARM sites

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Huang, Dong; Campos, Edwin; Liu, Yangang

    2014-09-17

    Statistical characteristics of cloud variability are examined for their dependence on averaging scales and best representation of probability density function with the decade-long retrieval products of cloud liquid water path (LWP) from the tropical western Pacific (TWP), Southern Great Plains (SGP), and North Slope of Alaska (NSA) sites of the Department of Energy’s Atmospheric Radiation Measurement Program. The statistical moments of LWP show some seasonal variation at the SGP and NSA sites but not much at the TWP site. It is found that the standard deviation, relative dispersion (the ratio of the standard deviation to the mean), and skewness allmore » quickly increase with the averaging window size when the window size is small and become more or less flat when the window size exceeds 12 h. On average, the cloud LWP at the TWP site has the largest values of standard deviation, relative dispersion, and skewness, whereas the NSA site exhibits the least. Correlation analysis shows that there is a positive correlation between the mean LWP and the standard deviation. The skewness is found to be closely related to the relative dispersion with a correlation coefficient of 0.6. The comparison further shows that the log normal, Weibull, and gamma distributions reasonably explain the observed relationship between skewness and relative dispersion over a wide range of scales.« less

  12. Prediction of mass transfer coefficient in rotating bed contactor (Higee) using artificial neural network

    NASA Astrophysics Data System (ADS)

    Saha, Dipendu

    2009-02-01

    The feasibility of drastically reducing the contactor size in mass transfer processes utilizing centrifugal field has generated a lot of interest in rotating packed bed (Higee). Various investigators have proposed correlations to predict mass transfer coefficients in Higee, but, none of the correlations was more than 20-30% accurate. In this work, artificial neural network (ANN) is employed for predicting mass transfer coefficient data. Results show that ANN provides better estimation of mass transfer coefficient with accuracy 5-15%.

  13. Intraclass Correlation Coefficients in Hierarchical Design Studies with Discrete Response Variables: A Note on a Direct Interval Estimation Procedure

    ERIC Educational Resources Information Center

    Raykov, Tenko; Marcoulides, George A.

    2015-01-01

    A latent variable modeling procedure that can be used to evaluate intraclass correlation coefficients in two-level settings with discrete response variables is discussed. The approach is readily applied when the purpose is to furnish confidence intervals at prespecified confidence levels for these coefficients in setups with binary or ordinal…

  14. Precancerous esophageal epithelia are associated with significantly increased scattering coefficients

    PubMed Central

    Su, Jing-Wei; Lin, Yang-Hsien; Chiang, Chun-Ping; Lee, Jang-Ming; Hsieh, Chao-Mao; Hsieh, Min-Shu; Yang, Pei-Wen; Wang, Chen-Ping; Tseng, Ping-Huei; Lee, Yi-Chia; Sung, Kung-Bin

    2015-01-01

    The progression of epithelial precancers into cancer is accompanied by changes of tissue and cellular structures in the epithelium. Correlations between the structural changes and scattering coefficients of esophageal epithelia were investigated using quantitative phase images and the scattering-phase theorem. An ex vivo study of 14 patients demonstrated that the average scattering coefficient of precancerous epithelia was 37.8% higher than that of normal epithelia from the same patient. The scattering coefficients were highly correlated with morphological features including the cell density and the nuclear-to-cytoplasmic ratio. A high interpatient variability in scattering coefficients was observed and suggests identifying precancerous lesions based on the relative change in scattering coefficients. PMID:26504630

  15. Comparison between uroflowmetry and sonouroflowmetry in recording of urinary flow in healthy men.

    PubMed

    Krhut, Jan; Gärtner, Marcel; Sýkora, Radek; Hurtík, Petr; Burda, Michal; Luňáček, Libor; Zvarová, Katarína; Zvara, Peter

    2015-08-01

    To evaluate the accuracy of sonouroflowmetry in recording urinary flow parameters and voided volume. A total of 25 healthy male volunteers (age 18-63 years) were included in the study. All participants were asked to carry out uroflowmetry synchronous with recording of the sound generated by the urine stream hitting the water level in the urine collection receptacle, using a dedicated cell phone. From 188 recordings, 34 were excluded, because of voided volume <150 mL or technical problems during recording. Sonouroflowmetry recording was visualized in a form of a trace, representing sound intensity over time. Subsequently, the matching datasets of uroflowmetry and sonouroflowmetry were compared with respect to flow time, voided volume, maximum flow rate and average flow rate. Pearson's correlation coefficient was used to compare parameters recorded by uroflowmetry with those calculated based on sonouroflowmetry recordings. The flow pattern recorded by sonouroflowmetry showed a good correlation with the uroflowmetry trace. A strong correlation (Pearson's correlation coefficient 0.87) was documented between uroflowmetry-recorded flow time and duration of the sound signal recorded with sonouroflowmetry. A moderate correlation was observed in voided volume (Pearson's correlation coefficient 0.68) and average flow rate (Pearson's correlation coefficient 0.57). A weak correlation (Pearson's correlation coefficient 0.38) between maximum flow rate recorded using uroflowmetry and sonouroflowmetry-recorded peak sound intensity was documented. The present study shows that the basic concept utilizing sound analysis for estimation of urinary flow parameters and voided volume is valid. However, further development of this technology and standardization of recording algorithm are required. © 2015 The Japanese Urological Association.

  16. Combinatorial Algorithms for Portfolio Optimization Problems - Case of Risk Moderate Investor

    NASA Astrophysics Data System (ADS)

    Juarna, A.

    2017-03-01

    Portfolio optimization problem is a problem of finding optimal combination of n stocks from N ≥ n available stocks that gives maximal aggregate return and minimal aggregate risk. In this paper given N = 43 from the IDX (Indonesia Stock Exchange) group of the 45 most-traded stocks, known as the LQ45, with p = 24 data of monthly returns for each stock, spanned over interval 2013-2014. This problem actually is a combinatorial one where its algorithm is constructed based on two considerations: risk moderate type of investor and maximum allowed correlation coefficient between every two eligible stocks. The main outputs resulted from implementation of the algorithms is a multiple curve of three portfolio’s attributes, e.g. the size, the ratio of return to risk, and the percentage of negative correlation coefficient for every two chosen stocks, as function of maximum allowed correlation coefficient between each two stocks. The output curve shows that the portfolio contains three stocks with ratio of return to risk at 14.57 if the maximum allowed correlation coefficient between every two eligible stocks is negative and contains 19 stocks with maximum allowed correlation coefficient 0.17 to get maximum ratio of return to risk at 25.48.

  17. AN EMPIRICAL INVESTIGATION OF THE EFFECTS OF NONNORMALITY UPON THE SAMPLING DISTRIBUTION OF THE PROJECT MOMENT CORRELATION COEFFICIENT.

    ERIC Educational Resources Information Center

    HJELM, HOWARD; NORRIS, RAYMOND C.

    THE STUDY EMPIRICALLY DETERMINED THE EFFECTS OF NONNORMALITY UPON SOME SAMPLING DISTRIBUTIONS OF THE PRODUCT MOMENT CORRELATION COEFFICIENT (PMCC). SAMPLING DISTRIBUTIONS OF THE PMCC WERE OBTAINED BY DRAWING NUMEROUS SAMPLES FROM CONTROL AND EXPERIMENTAL POPULATIONS HAVING VARIOUS DEGREES OF NONNORMALITY AND BY CALCULATING CORRELATION COEFFICIENTS…

  18. Gender and Age Analyses of NIRS/STAI Pearson Correlation Coefficients at Resting State.

    PubMed

    Matsumoto, T; Fuchita, Y; Ichikawa, K; Fukuda, Y; Takemura, N; Sakatani, K

    2016-01-01

    According to the valence asymmetry hypothesis, the left/right asymmetry of PFC activity is correlated with specific emotional responses to mental stress and personality traits. In a previous study we measured spontaneous oscillation of oxy-Hb concentrations in the bilateral PFC at rest in normal adults employing two-channel portable NIRS and computed the laterality index at rest (LIR). We investigated the Pearson correlation coefficient between the LIR and anxiety levels evaluated by the State-Trait Anxiety Inventory (STAI) test. We found that subjects with right-dominant activity at rest showed higher STAI scores, while those with left dominant oxy-Hb changes at rest showed lower STAI scores such that the Pearson correlation coefficient between LIR and STAI was positive. This study performed Bootstrap analysis on the data and showed the following statistics of the target correlation coefficient: mean=0.4925 and lower confidence limit=0.177 with confidence level 0.05. Using the KS-test, we demonstrated that the correlation did not depend on age, whereas it did depend on gender.

  19. Nuclear anxiety: a test-construction study

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Braunstein, A.L.

    1986-01-01

    The Nuclear Anxiety Scale was administered to 263 undergraduate and graduate studies (on eight occasions in December, 1985 and January, 1986). (1) The obtained alpha coefficient was .91. This was significant at the .01 level, and demonstrated that the scale was internally homogeneous and consistent. (2) Item discrimination indices (point biserial correlation coefficients) computered for the thirty (30) items yielded a range of .25 to .64. All coefficients were significant at the .01 level, and all 30 items were retained as demonstrating significant discriminability. (3) The correlation between two administrations of the scale (with a 48-hour interval) was .83. Thismore » was significant at the .01 level, and demonstrated test-retest reliability and stability over time. (4) The point-biserial correlation coefficient between scores on the Nuclear Anxiety Scale, and the students' self-report of nuclear anxiety as being either a high or low ranked stressor, was .59. This was significant at the .01 level, and demonstrated concurrent validity. (5) The correlation coefficient between scores on the Nuclear Anxiety Scale and the Spielberger State-Trait Anxiety Inventory, A-Trait, (1970), was .41. This was significant at the .01 level, and demonstrated convergent validity. (6) The correlation coefficient between positively stated and negatively stated items (with scoring reversed) was .76. This was significant at the .01 level, and demonstrated freedom from response set bias.« less

  20. Channel correlation and BER performance analysis of coherent optical communication systems with receive diversity over moderate-to-strong non-Kolmogorov turbulence.

    PubMed

    Fu, Yulong; Ma, Jing; Tan, Liying; Yu, Siyuan; Lu, Gaoyuan

    2018-04-10

    In this paper, new expressions of the channel-correlation coefficient and its components (the large- and small-scale channel-correlation coefficients) for a plane wave are derived for a horizontal link in moderate-to-strong non-Kolmogorov turbulence using a generalized effective atmospheric spectrum which includes finite-turbulence inner and outer scales and high-wave-number "bump". The closed-form expression of the average bit error rate (BER) of the coherent free-space optical communication system is derived using the derived channel-correlation coefficients and an α-μ distribution to approximate the sum of the square root of arbitrarily correlated Gamma-Gamma random variables. Analytical results are provided to investigate the channel correlation and evaluate the average BER performance. The validity of the proposed approximation is illustrated by Monte Carlo simulations. This work will help with further investigation of the fading correlation in spatial diversity systems.

  1. Technical characterization of dialysis fluid flow and mass transfer rate in dialyzers with various filtration coefficients using dimensionless correlation equation.

    PubMed

    Fukuda, Makoto; Yoshimura, Kengo; Namekawa, Koki; Sakai, Kiyotaka

    2017-06-01

    The objective of the present study is to evaluate the effect of filtration coefficient and internal filtration on dialysis fluid flow and mass transfer coefficient in dialyzers using dimensionless mass transfer correlation equations. Aqueous solution of vitamin B 12 clearances were obtained for REXEED-15L as a low flux dialyzer, and APS-15EA and APS-15UA as high flux dialyzers. All the other design specifications were identical for these dialyzers except for filtration coefficient. The overall mass transfer coefficient was calculated, moreover, the exponents of Reynolds number (Re) and film mass transfer coefficient of the dialysis-side fluid (k D ) for each flow rate were derived from the Wilson plot and dimensionless correlation equation. The exponents of Re were 0.4 for the low flux dialyzer whereas 0.5 for the high flux dialyzers. Dialysis fluid of the low flux dialyzer was close to laminar flow because of its low filtration coefficient. On the other hand, dialysis fluid of the high flux dialyzers was assumed to be orthogonal flow. Higher filtration coefficient was associated with higher k D influenced by mass transfer rate through diffusion and internal filtration. Higher filtration coefficient of dialyzers and internal filtration affect orthogonal flow of dialysis fluid.

  2. Detrended fluctuation analysis made flexible to detect range of cross-correlated fluctuations

    NASA Astrophysics Data System (ADS)

    Kwapień, Jarosław; Oświecimka, Paweł; DroŻdŻ, Stanisław

    2015-11-01

    The detrended cross-correlation coefficient ρDCCA has recently been proposed to quantify the strength of cross-correlations on different temporal scales in bivariate, nonstationary time series. It is based on the detrended cross-correlation and detrended fluctuation analyses (DCCA and DFA, respectively) and can be viewed as an analog of the Pearson coefficient in the case of the fluctuation analysis. The coefficient ρDCCA works well in many practical situations but by construction its applicability is limited to detection of whether two signals are generally cross-correlated, without the possibility to obtain information on the amplitude of fluctuations that are responsible for those cross-correlations. In order to introduce some related flexibility, here we propose an extension of ρDCCA that exploits the multifractal versions of DFA and DCCA: multifractal detrended fluctuation analysis and multifractal detrended cross-correlation analysis, respectively. The resulting new coefficient ρq not only is able to quantify the strength of correlations but also allows one to identify the range of detrended fluctuation amplitudes that are correlated in two signals under study. We show how the coefficient ρq works in practical situations by applying it to stochastic time series representing processes with long memory: autoregressive and multiplicative ones. Such processes are often used to model signals recorded from complex systems and complex physical phenomena like turbulence, so we are convinced that this new measure can successfully be applied in time-series analysis. In particular, we present an example of such application to highly complex empirical data from financial markets. The present formulation can straightforwardly be extended to multivariate data in terms of the q -dependent counterpart of the correlation matrices and then to the network representation.

  3. Influences of sampling size and pattern on the uncertainty of correlation estimation between soil water content and its influencing factors

    NASA Astrophysics Data System (ADS)

    Lai, Xiaoming; Zhu, Qing; Zhou, Zhiwen; Liao, Kaihua

    2017-12-01

    In this study, seven random combination sampling strategies were applied to investigate the uncertainties in estimating the hillslope mean soil water content (SWC) and correlation coefficients between the SWC and soil/terrain properties on a tea + bamboo hillslope. One of the sampling strategies is the global random sampling and the other six are the stratified random sampling on the top, middle, toe, top + mid, top + toe and mid + toe slope positions. When each sampling strategy was applied, sample sizes were gradually reduced and each sampling size contained 3000 replicates. Under each sampling size of each sampling strategy, the relative errors (REs) and coefficients of variation (CVs) of the estimated hillslope mean SWC and correlation coefficients between the SWC and soil/terrain properties were calculated to quantify the accuracy and uncertainty. The results showed that the uncertainty of the estimations decreased as the sampling size increasing. However, larger sample sizes were required to reduce the uncertainty in correlation coefficient estimation than in hillslope mean SWC estimation. Under global random sampling, 12 randomly sampled sites on this hillslope were adequate to estimate the hillslope mean SWC with RE and CV ≤10%. However, at least 72 randomly sampled sites were needed to ensure the estimated correlation coefficients with REs and CVs ≤10%. Comparing with all sampling strategies, reducing sampling sites on the middle slope had the least influence on the estimation of hillslope mean SWC and correlation coefficients. Under this strategy, 60 sites (10 on the middle slope and 50 on the top and toe slopes) were enough to ensure the estimated correlation coefficients with REs and CVs ≤10%. This suggested that when designing the SWC sampling, the proportion of sites on the middle slope can be reduced to 16.7% of the total number of sites. Findings of this study will be useful for the optimal SWC sampling design.

  4. NT-pro-BNP levels in patients with acute pulmonary embolism are correlated to right but not left ventricular volume and function.

    PubMed

    Pasha, Sharif M; Klok, Frederikus A; van der Bijl, Noortje; de Roos, Albert; Kroft, Lucia J M; Huisman, Menno V

    2012-08-01

    N-terminal pro-Brain Natriuretic Peptide (NT-pro-BNP) is primarily secreted by left ventricular (LV) stretch and wall tension. Notably, NT-pro-BNP is a prognostic marker in acute pulmonary embolism (PE), which primarily stresses the right ventricle (RV). We sought to evaluate the relative contribution of the RV to NT-pro-BNP levels during PE. A post-hoc analysis of an observational prospective outcome study in 113 consecutive patients with computed tomography (CT)-proven PE and 226 patients in whom PE was clinically suspected but ruled out by CT. In all patients RV and LV function was established by assessing ECG-triggered-CT measured ventricular end-diastolic-volumes and ejection fraction (EF). NT-pro-BNP was assessed in all patients. The correlation between RV and LV end-diastolic-volumes and systolic function was evaluated by multiple linear regression corrected for known confounders. In the PE cohort increased RVEF (β-coefficient (95% confidence interval [CI]) -0.044 (± -0.011); p<0.001) and higher RV end-diastolic-volume (β-coefficient 0.005 (± 0.001); p<0.001) were significantly correlated to NT-pro-BNP, while no correlation was found with LVEF (β-coefficient 0.005 (± 0.010); p=0.587) and LV end-diastolic-volume (β-coefficient -0.003 (± 0.002); p=0.074). In control patients without PE we found a strong correlation between NT-pro-BNP levels and LVEF (β-coefficient -0.027 (± -0.006); p<0.001) although not LV end-diastolic-volume (β-coefficient 0.001 (± 0.001); p=0.418). RVEF (β-coefficient -0.002 (± -0.006); p=0.802) and RV end-diastolic-volume (β-coefficient <0.001 (± 0.001); p=0.730) were not correlated in patients without PE. In PE patients, lower RVEF and higher RV end-diastolic-volume were significantly correlated to NT-pro-BNP levels as compared to control patients without PE. These observations provide pathophysiological ground for the well-known prognostic value of NT-pro-BNP in acute PE.

  5. Quantitative analysis of spatial variability of geotechnical parameters

    NASA Astrophysics Data System (ADS)

    Fang, Xing

    2018-04-01

    Geotechnical parameters are the basic parameters of geotechnical engineering design, while the geotechnical parameters have strong regional characteristics. At the same time, the spatial variability of geotechnical parameters has been recognized. It is gradually introduced into the reliability analysis of geotechnical engineering. Based on the statistical theory of geostatistical spatial information, the spatial variability of geotechnical parameters is quantitatively analyzed. At the same time, the evaluation of geotechnical parameters and the correlation coefficient between geotechnical parameters are calculated. A residential district of Tianjin Survey Institute was selected as the research object. There are 68 boreholes in this area and 9 layers of mechanical stratification. The parameters are water content, natural gravity, void ratio, liquid limit, plasticity index, liquidity index, compressibility coefficient, compressive modulus, internal friction angle, cohesion and SP index. According to the principle of statistical correlation, the correlation coefficient of geotechnical parameters is calculated. According to the correlation coefficient, the law of geotechnical parameters is obtained.

  6. Dynamics of surface temperatures at the Crimean peninsula territory

    NASA Astrophysics Data System (ADS)

    Danova, T. E.; Nikiforova, M. P.

    2017-11-01

    The analysis of the surface temperaturesvariability (monthly mean) over the period 1969-2014 by frequency of exceeding the climatic norm (1961-1990) is presented. An increaseof such situations in 3.5 times over entire Crimean peninsula territoryis revealed. "Strong exceeding" (from 2.0σ to 2.5σ) is characterized by an increase in the number of cases from 6% to 15% and "very strong exceeding" (> 2.5σ) - from 0% to 18%. The value of coefficients in the "very strong exceeding" reaches 5.9σ. The pronounced effect of surface air temperature growing indicates an increase in threats which creates thermal stress on human health. The main categories are vulnerable elderly people, as well as the people do not acclimate to an unfamiliar thermal environment (in this category in most of the representatives of the tourist flow). While maintaining the observed trends, extreme heat periods will be a serious threat to the health of persons that has "epidemical" potential in the European region.

  7. Seebeck Coefficient of Cation-Substituted Disulfides CuCr1-x Fe x S2 and Cu1-x Fe x CrS2

    NASA Astrophysics Data System (ADS)

    Korotaev, Evgeniy V.; Syrokvashin, Mikhail M.; Filatova, Irina Yu.; Pelmenev, Konstantin G.; Zvereva, Valentina V.; Peregudova, Natalya N.

    2018-03-01

    The effect of cation substitution on the Seebeck coefficient of CuCr1-x Fe x S2 (x = 0 to 0.30) and Cu1-x Fe x CrS2 (x = 0 to 0.03) in the temperature range of 100 K to 450 K has been investigated. Increasing iron concentration led to a metal-insulator transition which suppressed the thermoelectric power. However, for low iron concentration (x < 0.03), the Seebeck coefficient of CuCr1-x Fe x S2 and Cu1-x Fe x CrS2 exceeded the values for the undoped copper-chromium disulfide matrix CuCrS2 at temperature below 300 K.

  8. Coefficient of performance and its bounds with the figure of merit for a general refrigerator

    NASA Astrophysics Data System (ADS)

    Long, Rui; Liu, Wei

    2015-02-01

    A general refrigerator model with non-isothermal processes is studied. The coefficient of performance (COP) and its bounds at maximum χ figure of merit are obtained and analyzed. This model accounts for different heat capacities during the heat transfer processes. So, different kinds of refrigerator cycles can be considered. Under the constant heat capacity condition, the upper bound of the COP is the Curzon-Ahlborn (CA) coefficient of performance and is independent of the time durations of the heat exchanging processes. With the maximum χ criterion, in the refrigerator cycles, such as the reversed Brayton refrigerator cycle, the reversed Otto refrigerator cycle and the reversed Atkinson refrigerator cycle, where the heat capacity in the heat absorbing process is not less than that in the heat releasing process, their COPs are bounded by the CA coefficient of performance; otherwise, such as for the reversed Diesel refrigerator cycle, its COP can exceed the CA coefficient of performance. Furthermore, the general refined upper and lower bounds have been proposed.

  9. Gaussian process models for reference ET estimation from alternative meteorological data sources

    USDA-ARS?s Scientific Manuscript database

    Accurate estimates of daily crop evapotranspiration (ET) are needed for efficient irrigation management, especially in arid and semi-arid regions where crop water demand exceeds rainfall. Daily grass or alfalfa reference ET values and crop coefficients are widely used to estimate crop water demand. ...

  10. Some correlations between sugar maple tree characteristics and sap and sugar yields

    Treesearch

    Barton M. Blum

    1971-01-01

    Simple correlation coefficients between various characteristics of sugar maple trees and sap sugar concentration, sap volume yield, and total sugar production are given for the 1968 sap season. Correlation coefficients in general indicated that individual tree characteristics that express tree and crown size are significantly related to sap volume yield and total sugar...

  11. Reducing Bias and Error in the Correlation Coefficient Due to Nonnormality

    ERIC Educational Resources Information Center

    Bishara, Anthony J.; Hittner, James B.

    2015-01-01

    It is more common for educational and psychological data to be nonnormal than to be approximately normal. This tendency may lead to bias and error in point estimates of the Pearson correlation coefficient. In a series of Monte Carlo simulations, the Pearson correlation was examined under conditions of normal and nonnormal data, and it was compared…

  12. Relationship of body mass index to percent body fat and waist circumference among schoolchildren in Japan - the influence of gender and obesity: a population-based cross-sectional study

    PubMed Central

    2010-01-01

    Background Although the correlation coefficient between body mass index (BMI) and percent body fat (%BF) or waist circumference (WC) has been reported, studies conducted among population-based schoolchildren to date have been limited in Japan, where %BF and WC are not usually measured in annual health examinations at elementary schools or junior high schools. The aim of the present study was to investigate the relationship of BMI to %BF and WC and to examine the influence of gender and obesity on these relationships among Japanese schoolchildren. Methods Subjects included 3,750 schoolchildren from the fourth and seventh grade in Ina-town, Saitama Prefecture, Japan between 2004 and 2008. Information about subject's age, sex, height, weight, %BF, and WC was collected from annual physical examinations. %BF was measured with a bipedal biometrical impedance analysis device. Obesity was defined by the following two criteria: the obese definition of the Centers for Disease Control and Prevention, and the definition of obesity for Japanese children. Pearson's correlation coefficients between BMI and %BF or WC were calculated separately for sex. Results Among fourth graders, the correlation coefficients between BMI and %BF were 0.74 for boys and 0.97 for girls, whereas those between BMI and WC were 0.94 for boys and 0.90 for girls. Similar results were observed in the analysis of seventh graders. The correlation coefficient between BMI and %BF varied by physique (obese or non-obese), with weaker correlations among the obese regardless of the definition of obesity; most correlation coefficients among obese boys were less than 0.5, whereas most correlations among obese girls were more than 0.7. On the other hand, the correlation coefficients between BMI and WC were more than 0.8 among boys and almost all coefficients were more than 0.7 among girls, regardless of physique. Conclusions BMI was positively correlated with %BF and WC among Japanese schoolchildren. The correlations could be influenced by obesity as well as by gender. Accordingly, it is essential to consider gender and obesity when using BMI as a surrogate for %BF and WC for epidemiological use. PMID:20716379

  13. A screening-level modeling approach to estimate nitrogen ...

    EPA Pesticide Factsheets

    This paper presents a screening-level modeling approach that can be used to rapidly estimate nutrient loading and assess numerical nutrient standard exceedance risk of surface waters leading to potential classification as impaired for designated use. It can also be used to explore best management practice (BMP) implementation to reduce loading. The modeling framework uses a hybrid statistical and process based approach to estimate source of pollutants, their transport and decay in the terrestrial and aquatic parts of watersheds. The framework is developed in the ArcGIS environment and is based on the total maximum daily load (TMDL) balance model. Nitrogen (N) is currently addressed in the framework, referred to as WQM-TMDL-N. Loading for each catchment includes non-point sources (NPS) and point sources (PS). NPS loading is estimated using export coefficient or event mean concentration methods depending on the temporal scales, i.e., annual or daily. Loading from atmospheric deposition is also included. The probability of a nutrient load to exceed a target load is evaluated using probabilistic risk assessment, by including the uncertainty associated with export coefficients of various land uses. The computed risk data can be visualized as spatial maps which show the load exceedance probability for all stream segments. In an application of this modeling approach to the Tippecanoe River watershed in Indiana, USA, total nitrogen (TN) loading and risk of standard exce

  14. Determining Sample Size for Accurate Estimation of the Squared Multiple Correlation Coefficient.

    ERIC Educational Resources Information Center

    Algina, James; Olejnik, Stephen

    2000-01-01

    Discusses determining sample size for estimation of the squared multiple correlation coefficient and presents regression equations that permit determination of the sample size for estimating this parameter for up to 20 predictor variables. (SLD)

  15. Effect of degree correlations above the first shell on the percolation transition

    NASA Astrophysics Data System (ADS)

    Valdez, L. D.; Buono, C.; Braunstein, L. A.; Macri, P. A.

    2011-11-01

    The use of degree-degree correlations to model realistic networks which are characterized by their Pearson's coefficient, has become widespread. However the effect on how different correlation algorithms produce different results on processes on top of them, has not yet been discussed. In this letter, using different correlation algorithms to generate assortative networks, we show that for very assortative networks the behavior of the main observables in percolation processes depends on the algorithm used to build the network. The different alghoritms used here introduce different inner structures that are missed in Pearson's coefficient. We explain the different behaviors through a generalization of Pearson's coefficient that allows to study the correlations at chemical distances l from a root node. We apply our findings to real networks.

  16. Evaluation of generalized heat-transfer coefficients in pilot AFBC units

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Grewal, N.S.

    Experimental data for heat transfer rates as obtained in a 0.209m/sup 2/ AFBC unit at the GFETC is examined in the light of the existing four correlations for heat transfer coefficient between an immersed staggered array of horizontal tubes and a gas-solid fluidized bed. The predicted values of heat transfer coefficient from the correlations proposed by Grewal and Bansal are found to be in good agreement with the experimental values of heat transfer coefficient when the contribution due to radiation is also included.

  17. Evaluation of generalized heat transfer coefficients in pilot AFBC units

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Grewal, N.S.

    Experimental data for heat transfer rates as obtained in a 0.209m/sup 2/ AFBC unit at the GFETC is examined in the light of the existing four correlations for heat transfer coefficient between an immersed staggered array of horizontal tubes and a gas-solid fluidized bed. The predicted values of heat transfer coefficient from the correlations proposed by Grewal and Bansal are found to be in good agreement with the experimental values of heat transfer coefficient when the contribution due to radiation is also included.

  18. Sensitivity of amplitude-phase characteristics of the surface air temperature annual cycle to variations in annual mean temperature

    NASA Astrophysics Data System (ADS)

    Eliseev, A. V.; Mokhov, I. I.; Guseva, M. S.

    2006-05-01

    The ERA40 and NCEP/NCAR data over 1958 1998 were used to estimate the sensitivity of amplitude-phase characteristics (APCs) of the annual cycle (AC) of the surface air temperature (SAT) T s. The results were compared with outputs of the ECHAM4/OPYC3, HadCM3, and INM RAS general circulation models and the IAP RAS climate model of intermediate complexity, which were run with variations in greenhouse gases and sulfate aerosol specified over 1860 2100. The analysis was performed in terms of the linear regression coefficients b of SAT AC APCs on the local annual mean temperature and in terms of the sensitivity characteristic D = br 2, which takes into account not only the linear regression coefficient but also its statistical significance (via the correlation coefficient r). The reanalysis data were used to reveal the features of the tendencies of change in the SAT AC APCs in various regions, including areas near the snow-ice boundary, storm-track ocean regions, large desert areas, and the tropical Pacific. These results agree with earlier observations. The model computations are in fairly good agreement with the reanalysis data in regions of statistically significant variations in SAT AC APCs. The differences between individual models and the reanalysis data can be explained, in particular, in terms of the features of the sea-ice schemes used in the models. Over the land in the middle and high latitudes of the Northern Hemisphere, the absolute values of D for the fall phase time and the interval of exceeding exhibit a positive intermodel correlation with the absolute value of D for the annual-harmonic amplitude. Over the ocean, the models reproducing larger (in modulus) sensitivity parameters of the SAT annual-harmonic amplitude are generally characterized by larger (in modulus) negative sensitivity values of the semiannual-harmonic amplitude T s, 2, especially at latitudes characteristic of the sea-ice boundary. In contrast to the averaged fields of AC APCs and their interannual standard deviations, the sensitivity parameters of the SAT AC APCs on a regional scale vary noticeably for various types of anthropogenic forcing.

  19. A Review of Evidence for High Life Coefficients on Propeller and Rotor Blades Under Static Thrust Conditions with Some New Experimental Results

    NASA Technical Reports Server (NTRS)

    Talbot, Peter D.; Meyer, Mark; Branum, Lonnie; Burks, John S. (Technical Monitor)

    1994-01-01

    Interest has increased recently in the thrust-producing capability of rotors at very high collective pitch angles. An early reference noted this behaviour in rotors and offered alternative models for section lift characteristics to explain it. The same phenomenon was coincidentally noted and used in a propeller code, resulting in very good correlation with static thrust data. The proposed paper will present experimental data demonstrating the pronounced persistence of thrust for propellers at increasing collective pitch angles. Comparisons with blade element/momentum theory will be made. These results are expected to point to the need to define (ultimately to explain) aerodynamic lift and drag behaviour in a rotating environment. Experimental measurements made by the U.S. Army Aeroflightdynamics Directorate at the Ames Research Center have shown that locally measured normal force coefficients along the span of a highly twisted rotor blade continue to increase at high values of collective pitch. In some cases these coefficients exceed expected values for the same type of airfoil tested under two dimensional conditions. To date no one to the authors' knowledge has defined the variation of C(n) with pitch for very high angles (to 45 deg) in a rotating environment and for a blade of reasonably high aspect ratio; however, total propeller thrust measurements support the idea that stalling does not occur in the same way as on a wing. This paper will present experimental data in the form of surface pressure distributions as well as flow visualization (microtufts) to explore the aerodynamic behavior of the rotating airfoil at high values of blade incidence. This paper also reviews experimental evidence and infers some high lift coefficient behavior from it. Comparisons between predicted thrust, utilizing modified airfoil characteristics and a blade element model, and measured thrust for both rotors and propellers that cover the extremes of collective pitch are shown and discussed.

  20. Is there a systematic bias of apparent diffusion coefficient (ADC) measurements of the breast if measured on different workstations? An inter- and intra-reader agreement study.

    PubMed

    Clauser, Paola; Marcon, Magda; Maieron, Marta; Zuiani, Chiara; Bazzocchi, Massimo; Baltzer, Pascal A T

    2016-07-01

    To evaluate the influence of post-processing systems, intra- and inter-reader agreement on the variability of apparent diffusion coefficient (ADC) measurements in breast lesions. Forty-one patients with 41 biopsy-proven breast lesions gave their informed consent and were included in this prospective IRB-approved study. Magnetic resonance imaging (MRI) examinations were performed at 1.5 T using an EPI-DWI sequence, with b-values of 0 and 1000 s/mm(2). Two radiologists (R1, R2) reviewed the images in separate sessions and measured the ADC for lesion, using MRI-workstation (S-WS), PACS-workstation (P-WS) and a commercial DICOM viewer (O-SW). Agreement was evaluated using the intraclass correlation coefficient (ICC), Bland-Altman plots and coefficient of variation (CV). Thirty-one malignant, two high-risk and eight benign mass-like lesions were analysed. Intra-reader agreement was almost perfect (ICC-R1 = 0.974; ICC-R2 = 0.990) while inter-reader agreement was substantial (ICC from 0.615 to 0.682). Bland-Altman plots revealed a significant bias in ADC values measured between O-SW and S-WS (P = 0.025), no further systematic differences were identified. CV varied from 6.8 % to 7.9 %. Post-processing systems may have a significant, although minor, impact on ADC measurements in breast lesions. While intra-reader agreement is high, the main source of ADC variability seems to be caused by inter-reader variation. • ADC provides quantitative information on breast lesions independent from the system used. • ADC measurement using different workstations and software systems is generally reliable. • Systematic, but minor, differences may occur between different post-processing systems. • Inter-reader agreement of ADC measurements exceeded intra-reader agreement.

  1. Directional Solidification and Characterization of Hg(0.89) Mn(0.11)Te

    NASA Technical Reports Server (NTRS)

    Price, M. W.; Scripa, R. N.; Lehoczky. S. L.; Szofran, F. R.; Su, C.-H.

    1998-01-01

    Two boules of Hg(0.89)Mn(0.11)Te(MMT) were solidified using the vertical Bridgman-Stockbarger method. Translation rates of 0.09 and 0. 18 microns/s were used. The influence of growth rate on axial compositional homogeneity in the MMT boules was evaluated experimentally by conducting precision density measurements on radial slices taken from each boule. In addition, Plane Front Solidification theory and segregation coefficient (k) data for the Hg(1-x)Mn(x)Te system were used to fit theoretical composition profiles to the measured MMT axial composition profiles. The strong correlation between the measured and calculated MMT axial composition profiles indicates diffusion dominated axial solute redistribution in the boules under the applied growth conditions. The analysis of the MMT axial composition profiles by Plane Front Solidification theory allowed the calculation of the effective diffusion coefficient (D(eff) = 3.5 x l0(exp -5) sq cm/s). The k-values for the Hg(1-x)Mn(x)Te system and the D(sub eff) - value were then used to verify that both boules were solidified under conditions which did not exceed the Constitutional Supercooling Criteria under ideal conditions. Finally, a preliminary examination of the radial compositional variation in each MMT was made using Fourier Transform Infra-Red Spectroscopy (FTIR). The radial homogeneity in the MMT boules was found to be comparable for both translation rates.

  2. Air Quality in Lanzhou, a Major Industrial City in China: Characteristics of Air Pollution and Review of Existing Evidence from Air Pollution and Health Studies.

    PubMed

    Zhang, Yaqun; Li, Min; Bravo, Mercedes A; Jin, Lan; Nori-Sarma, Amruta; Xu, Yanwen; Guan, Donghong; Wang, Chengyuan; Chen, Mingxia; Wang, Xiao; Tao, Wei; Qiu, Weitao; Zhang, Yawei; Bell, Michelle L

    2014-10-01

    Air pollution contributes substantially to global health burdens; however, less is known about pollution patterns in China and whether they differ from those elsewhere. We evaluated temporal and spatial heterogeneity of air pollution in Lanzhou, an urban Chinese city (April 2009-December 2012), and conducted a systematic review of literature on air pollution and health in Lanzhou. Average levels were 141.5, 42.3, and 47.2 µg/m 3 for particulate matter with an aerodynamic diameter ≤10 µm (PM 10 ), NO 2 , and SO 2 , respectively. Findings suggest some seasonality, particularly for SO 2 , with higher concentrations during colder months relative to warmer months, although a longer time frame of data is needed to evaluate seasonality fully. Correlation coefficients generally declined with distance between monitors, while coefficients of divergence increased with distance. However, these trends were not statistically significant. PM 10 levels exceeded Chinese and other health-based standards and guidelines. The review identified 13 studies on outdoor air pollution and health. Although limited, the studies indicate that air pollution is associated with increased risk of health outcomes in Lanzhou. These studies and the high air pollution levels suggest potentially serious health consequences. Findings can provide guidance to future epidemiological studies, monitor placement programs, and air quality policies.

  3. Air Quality in Lanzhou, a Major Industrial City in China: Characteristics of Air Pollution and Review of Existing Evidence from Air Pollution and Health Studies

    PubMed Central

    Zhang, Yaqun; Li, Min; Bravo, Mercedes A.; Jin, Lan; Nori-Sarma, Amruta; Xu, Yanwen; Guan, Donghong; Wang, Chengyuan; Chen, Mingxia; Wang, Xiao; Tao, Wei; Qiu, Weitao; Zhang, Yawei

    2015-01-01

    Air pollution contributes substantially to global health burdens; however, less is known about pollution patterns in China and whether they differ from those elsewhere. We evaluated temporal and spatial heterogeneity of air pollution in Lanzhou, an urban Chinese city (April 2009–December 2012), and conducted a systematic review of literature on air pollution and health in Lanzhou. Average levels were 141.5, 42.3, and 47.2 µg/m3 for particulate matter with an aerodynamic diameter ≤10 µm (PM10), NO2, and SO2, respectively. Findings suggest some seasonality, particularly for SO2, with higher concentrations during colder months relative to warmer months, although a longer time frame of data is needed to evaluate seasonality fully. Correlation coefficients generally declined with distance between monitors, while coefficients of divergence increased with distance. However, these trends were not statistically significant. PM10 levels exceeded Chinese and other health-based standards and guidelines. The review identified 13 studies on outdoor air pollution and health. Although limited, the studies indicate that air pollution is associated with increased risk of health outcomes in Lanzhou. These studies and the high air pollution levels suggest potentially serious health consequences. Findings can provide guidance to future epidemiological studies, monitor placement programs, and air quality policies. PMID:25838615

  4. Variability in the Correlation between Asian Dust Storms and Chlorophyll a Concentration from the North to Equatorial Pacific

    PubMed Central

    Tan, Sai-Chun; Yao, Xiaohong; Gao, Hui-Wang; Shi, Guang-Yu; Yue, Xu

    2013-01-01

    A long-term record of Asian dust storms showed seven high-occurrence-frequency centers in China. The intrusion of Asian dust into the downwind seas, including the China seas, the Sea of Japan, the subarctic North Pacific, the North Pacific subtropical gyre, and the western and eastern Equatorial Pacific, has been shown to add nutrients to ocean ecosystems and enhance their biological activities. To explore the relationship between the transported dust from various sources to the six seas and oceanic biological activities with different nutrient conditions, the correlation between monthly chlorophyll a concentration in each sea and monthly dust storm occurrence frequencies reaching the sea during 1997–2007 was examined in this study. No correlations were observed between dust and chlorophyll a concentration in the <50 m China seas because atmospheric deposition is commonly believed to exert less impact on coastal seas. Significant correlations existed between dust sources and many sea areas, suggesting a link between dust and chlorophyll a concentration in those seas. However, the correlation coefficients were highly variable. In general, the correlation coefficients (0.54–0.63) for the Sea of Japan were highest, except for that between the subarctic Pacific and the Taklimakan Desert, where it was as high as 0.7. For the >50 m China seas and the North Pacific subtropical gyre, the correlation coefficients were in the range 0.32–0.57. The correlation coefficients for the western and eastern Equatorial Pacific were relatively low (<0.36). These correlation coefficients were further interpreted in terms of the geographical distributions of dust sources, the transport pathways, the dust deposition, the nutrient conditions of oceans, and the probability of dust storms reaching the seas. PMID:23460892

  5. Variability in the correlation between Asian dust storms and chlorophyll a concentration from the North to Equatorial Pacific.

    PubMed

    Tan, Sai-Chun; Yao, Xiaohong; Gao, Hui-Wang; Shi, Guang-Yu; Yue, Xu

    2013-01-01

    A long-term record of Asian dust storms showed seven high-occurrence-frequency centers in China. The intrusion of Asian dust into the downwind seas, including the China seas, the Sea of Japan, the subarctic North Pacific, the North Pacific subtropical gyre, and the western and eastern Equatorial Pacific, has been shown to add nutrients to ocean ecosystems and enhance their biological activities. To explore the relationship between the transported dust from various sources to the six seas and oceanic biological activities with different nutrient conditions, the correlation between monthly chlorophyll a concentration in each sea and monthly dust storm occurrence frequencies reaching the sea during 1997-2007 was examined in this study. No correlations were observed between dust and chlorophyll a concentration in the <50 m China seas because atmospheric deposition is commonly believed to exert less impact on coastal seas. Significant correlations existed between dust sources and many sea areas, suggesting a link between dust and chlorophyll a concentration in those seas. However, the correlation coefficients were highly variable. In general, the correlation coefficients (0.54-0.63) for the Sea of Japan were highest, except for that between the subarctic Pacific and the Taklimakan Desert, where it was as high as 0.7. For the >50 m China seas and the North Pacific subtropical gyre, the correlation coefficients were in the range 0.32-0.57. The correlation coefficients for the western and eastern Equatorial Pacific were relatively low (<0.36). These correlation coefficients were further interpreted in terms of the geographical distributions of dust sources, the transport pathways, the dust deposition, the nutrient conditions of oceans, and the probability of dust storms reaching the seas.

  6. Correlations between symptoms, nasal endoscopy, and in-office computed tomography in post-surgical chronic rhinosinusitis patients.

    PubMed

    Ryan, William R; Ramachandra, Tara; Hwang, Peter H

    2011-03-01

    To determine correlations between symptoms, nasal endoscopy findings, and computed tomography (CT) scan findings in post-surgical chronic rhinosinusitis (CRS) patients. Cross-sectional. A total of 51 CRS patients who had undergone endoscopic sinus surgery (ESS) completed symptom questionnaires, underwent endoscopy, and received an in-office sinus CT scan during one clinic visit. For metrics, we used the Sinonasal Outcomes Test-20 (SNOT-20) questionnaire, visual analog symptom scale (VAS), Lund-Kennedy endoscopy scoring scale, and Lund-MacKay (LM) CT scoring scale. We determined Pearson correlation coefficients, sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) between scores for symptoms, endoscopy, and CT. The SNOT-20 score and most VAS symptoms had poor correlation coefficients with both endoscopy and CT scores (0.03-0.24). Nasal drainage of pus, nasal congestion, and impaired sense of smell had moderate correlation coefficients with endoscopy and CT (0.24-0.42). Endoscopy had a strong correlation coefficient with CT (0.76). Drainage, edema, and polyps had strong correlation coefficients with CT (0.80, 0.69, and 0.49, respectively). Endoscopy had a PPV of 92.5% and NPV of 45.5% for detecting an abnormal sinus CT (LM score ≥1). In post-ESS CRS patients, most symptoms do not correlate well with either endoscopy or CT findings. Endoscopy and CT scores correlate well. Abnormal endoscopy findings have the ability to confidently rule in the presence of CT opacification, thus validating the importance of endoscopy in clinical decision making. However, a normal endoscopy cannot assure a normal CT. Thus, symptoms, endoscopy, and CT are complementary in the evaluation of the post-ESS CRS patient. Copyright © 2011 The American Laryngological, Rhinological, and Otological Society, Inc., Rhinological, and Otological Society, Inc.

  7. An experimental study on the noise correlation properties of CBCT projection data

    NASA Astrophysics Data System (ADS)

    Zhang, Hua; Ouyang, Luo; Ma, Jianhua; Huang, Jing; Chen, Wufan; Wang, Jing

    2014-03-01

    In this study, we systematically investigated the noise correlation properties among detector bins of CBCT projection data by analyzing repeated projection measurements. The measurements were performed on a TrueBeam on-board CBCT imaging system with a 4030CB flat panel detector. An anthropomorphic male pelvis phantom was used to acquire 500 repeated projection data at six different dose levels from 0.1 mAs to 1.6 mAs per projection at three fixed angles. To minimize the influence of the lag effect, lag correction was performed on the consecutively acquired projection data. The noise correlation coefficient between detector bin pairs was calculated from the corrected projection data. The noise correlation among CBCT projection data was then incorporated into the covariance matrix of the penalized weighted least-squares (PWLS) criterion for noise reduction of low-dose CBCT. The analyses of the repeated measurements show that noise correlation coefficients are non-zero between the nearest neighboring bins of CBCT projection data. The average noise correlation coefficients for the first- and second- order neighbors are 0.20 and 0.06, respectively. The noise correlation coefficients are independent of the dose level. Reconstruction of the pelvis phantom shows that the PWLS criterion with consideration of noise correlation results in a lower noise level as compared to the PWLS criterion without considering the noise correlation at the matched resolution.

  8. Microbial community related to lysozyme digestion process for boosting waste activated sludge biodegradability.

    PubMed

    Xin, Xiao-Dong; He, Jun-Guo; Qiu, Wei; Tang, Jian; Liu, Tian-Tian

    2015-01-01

    Waste activated sludge from a lab-scale sequencing batch reactor was used to investigate the potential relation of microbial community with lysozyme digestion process for sludge solubilization. The results showed the microbial community shifted conspicuously as sludge suffered lysozyme digestion. Soluble protein and polysaccharide kept an increasing trend in solution followed with succession of microbial community. The rise of lysozyme dosage augmented the dissimilarity among communities in various digested sludge. A negative relationship presented between community diversity and lysozyme digestion process under various lysozyme/TS from 0 to 240min (correlation coefficient R(2) exceeded 0.9). Pareto-Lorenz curves demonstrated that microbial community tended to be even with sludge disintegration process by lysozyme. Finally, with diversity (H) decrease and community distribution getting even, the SCOD/TCOD increased steadily in solution which suggested the sludge with high community diversity and uneven population distribution might have tremendous potential for improving their biodegradability by lysozyme digestion. Copyright © 2014 Elsevier Ltd. All rights reserved.

  9. Selenium in fly ash

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gutenmann, W.H.; Bache, C.A.; Youngs, W.D.

    1976-03-05

    Selenium, at concentrations exceeding 200 parts per million (ppM) (dry weight), has been found in white sweet clover voluntarily growing on beds of fly ash in central New York State. Guinea pigs fed such clover concentrated selenium in their tissues. The contents of the honey stomachs of bees foraging on this seleniferous clover contained negligible selenium. Mature vegetables cultured on 10 percent (by weight) fly ash-amended soil absorbed up to 1 ppM of selenium. Fly ashes from 21 states contained total selenium contents ranging from 1.2 to 16.5 ppM. Cabbage grown on soil containing 10 percent (by weight) of thesemore » fly ashes absorbed selenium (up to 3.7 ppM) in direct proportion (correlation coefficient r = .89) to the selenium concentration in the respective fly ash. Water, aquatic weeds, algae, dragonfly nymphs, polliwogs, and tissues of bullheads and muskrats from a fly ash-contaminated pond contained concentrations of selenium markedly elevated over those of controls.« less

  10. Relationship between Organizational Perceived Justice and Organizational Citizenship Behavior among an Iranian Hospital's Employees, 2013.

    PubMed

    Bahrami, Mohammad Amin; Montazeralfaraj, Razieh; Gazar, Saeed Hashemi; Tafti, Arefeh Dehghani

    2014-01-01

    Organizational citizenship behavior just referred to a set of discretionary workplace behaviors that exceed one's job requirements. The main objective of this study was to determine the relationship between organizational perceived justice and organizational citizenship behavior. This cross-sectional study was done in Shahid Sadoughi Hospital in Yazd, Iran in 2013. A total of 100 hospital employees contributed in the study. The required data was gathered using 2 valid questionnaires, including the Moorman & Niehoff organizational perceived justice questionnaire and the McKinsey organizational citizenship behavior questionnaire. Data were analyzed using SPSS version 16. Descriptive statistics, Chi square, and Pearson's correlation coefficient were used for data analysis. There was a significant positive relationship between organizational perceived justice and organizational citizenship behavior among the studied hospital's employees (P ≤ 0.05, R = 0.33). This study confirmed that any policy that leads to better organizational justice perception will contribute in better organizational citizenship behavior which will increase the hospital's productivity.

  11. Closure and ratio correlation analysis of lunar chemical and grain size data

    NASA Technical Reports Server (NTRS)

    Butler, J. C.

    1976-01-01

    Major element and major element plus trace element analyses were selected from the lunar data base for Apollo 11, 12 and 15 basalt and regolith samples. Summary statistics for each of the six data sets were compiled, and the effects of closure on the Pearson product moment correlation coefficient were investigated using the Chayes and Kruskal approximation procedure. In general, there are two types of closure effects evident in these data sets: negative correlations of intermediate size which are solely the result of closure, and correlations of small absolute value which depart significantly from their expected closure correlations which are of intermediate size. It is shown that a positive closure correlation will arise only when the product of the coefficients of variation is very small (less than 0.01 for most data sets) and, in general, trace elements in the lunar data sets exhibit relatively large coefficients of variation.

  12. Correlation Between Posttraumatic Growth and Posttraumatic Stress Disorder Symptoms Based on Pearson Correlation Coefficient: A Meta-Analysis.

    PubMed

    Liu, An-Nuo; Wang, Lu-Lu; Li, Hui-Ping; Gong, Juan; Liu, Xiao-Hong

    2017-05-01

    The literature on posttraumatic growth (PTG) is burgeoning, with the inconsistencies in the literature of the relationship between PTG and posttraumatic stress disorder (PTSD) symptoms becoming a focal point of attention. Thus, this meta-analysis aims to explore the relationship between PTG and PTSD symptoms through the Pearson correlation coefficient. A systematic search of the literature from January 1996 to November 2015 was completed. We retrieved reports on 63 studies that involved 26,951 patients. The weighted correlation coefficient revealed an effect size of 0.22 with a 95% confidence interval of 0.18 to 0.25. Meta-analysis provides evidence that PTG may be positively correlated with PTSD symptoms and that this correlation may be modified by age, trauma type, and time since trauma. Accordingly, people with high levels of PTG should not be ignored, but rather, they should continue to receive help to alleviate their PTSD symptoms.

  13. [Examination of diagnosis procedure combination survey data that influence function evaluation coefficient II].

    PubMed

    Nakajima, Hisato; Yano, Kouya; Nagasawa, Kaoko; Kobayashi, Eiji; Yokota, Kuninobu

    2015-01-01

    On the basis of Diagnosis Procedure Combination (DPC) survey data, the factors that increase the value of function evaluation coefficient II were considered. A total of 1,505 hospitals were divided into groups I, II, and III, and the following items were considered. 1. Significant differences in function evaluation coefficient II and DPC survey data. 2. Examination of using the Mahalanobis-Taguchi (MT) method. 3. Correlation between function evaluation coefficient II and each DPC survey data item. 1. Function evaluation coefficient II was highest in group II. Group I hospitals showed the highest bed capacity, and numbers of hospitalization days, operations, chemotherapies, radiotherapies and general anesthesia procedures. 2. Using the MT method, we found that the number of ambulance conveyances was effective factor in group I hospitals, the number of general anesthesia procedures was effective factor in group II hospitals, and the bed capacity was effective factor in group III hospitals. 3. In group I hospitals, function evaluation coefficient II significantly correlated to the numbers of ambulance conveyances and chemotherapies. In group II hospitals, function evaluation coefficient II significantly correlated to bed capacity, the numbers of ambulance conveyances, hospitalization days, operations, general anesthesia procedures, and mean hospitalization days. In group III hospitals, function evaluation coefficient II significantly correlated to all items. The factors that improve the value of function evaluation coefficient II were the increases in the numbers of ambulance conveyances, chemotherapies and radiotherapies in group I hospitals, increases in the numbers of hospitalization days, operations, ambulance conveyances and general anesthesia procedures in group II hospitals, and increases in the numbers of hospitalization days, operations and ambulance conveyances. These results indicate that the profit of a hospital will increase, which will lead to medical services of good quality.

  14. Estimating a graphical intra-class correlation coefficient (GICC) using multivariate probit-linear mixed models.

    PubMed

    Yue, Chen; Chen, Shaojie; Sair, Haris I; Airan, Raag; Caffo, Brian S

    2015-09-01

    Data reproducibility is a critical issue in all scientific experiments. In this manuscript, the problem of quantifying the reproducibility of graphical measurements is considered. The image intra-class correlation coefficient (I2C2) is generalized and the graphical intra-class correlation coefficient (GICC) is proposed for such purpose. The concept for GICC is based on multivariate probit-linear mixed effect models. A Markov Chain Monte Carlo EM (mcm-cEM) algorithm is used for estimating the GICC. Simulation results with varied settings are demonstrated and our method is applied to the KIRBY21 test-retest dataset.

  15. QSAR modeling of flotation collectors using principal components extracted from topological indices.

    PubMed

    Natarajan, R; Nirdosh, Inderjit; Basak, Subhash C; Mills, Denise R

    2002-01-01

    Several topological indices were calculated for substituted-cupferrons that were tested as collectors for the froth flotation of uranium. The principal component analysis (PCA) was used for data reduction. Seven principal components (PC) were found to account for 98.6% of the variance among the computed indices. The principal components thus extracted were used in stepwise regression analyses to construct regression models for the prediction of separation efficiencies (Es) of the collectors. A two-parameter model with a correlation coefficient of 0.889 and a three-parameter model with a correlation coefficient of 0.913 were formed. PCs were found to be better than partition coefficient to form regression equations, and inclusion of an electronic parameter such as Hammett sigma or quantum mechanically derived electronic charges on the chelating atoms did not improve the correlation coefficient significantly. The method was extended to model the separation efficiencies of mercaptobenzothiazoles (MBT) and aminothiophenols (ATP) used in the flotation of lead and zinc ores, respectively. Five principal components were found to explain 99% of the data variability in each series. A three-parameter equation with correlation coefficient of 0.985 and a two-parameter equation with correlation coefficient of 0.926 were obtained for MBT and ATP, respectively. The amenability of separation efficiencies of chelating collectors to QSAR modeling using PCs based on topological indices might lead to the selection of collectors for synthesis and testing from a virtual database.

  16. Different hip and knee priority score systems: are they good for the same thing?

    PubMed

    Escobar, Antonio; Quintana, Jose Maria; Espallargues, Mireia; Allepuz, Alejandro; Ibañez, Berta

    2010-10-01

    The aim of the present study was to compare two priority tools used for joint replacement for patients on waiting lists, which use two different methods. Two prioritization tools developed and validated by different methodologies were used on the same cohort of patients. The first, an IRYSS hip and knee priority score (IHKPS) developed by RAND method, was applied while patients were on the waiting list. The other, a Catalonia hip-knee priority score (CHKPS) developed by conjoint analysis, was adapted and applied retrospectively. In addition, all patients fulfilled pre-intervention the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). Correlation between them was studied by Pearson correlation coefficient (r). Agreement was analysed by means of intra-class correlation coefficient (ICC), Kendall coefficient and Cohern kappa. The relationship between IHKPS, CHKPS and baseline WOMAC scores by r coefficient was studied. The sample consisted of 774 consecutive patients. Pearson correlation coefficient between IHKPS and CHKPS was 0.79. The agreement study showed that ICC was 0.74, Kendall coefficient 0.86 and kappa 0.66. Finally, correlation between CHKPS and baseline WOMAC ranged from 0.43 to 0.64. The results according to the relationship between IHKPS and WOMAC ranged from 0.50 to 0.74. Results support the hypothesis that if the final objective of the prioritization tools is to organize and sort patients on the waiting list, although they use different methodologies, the results are similar. © 2010 Blackwell Publishing Ltd.

  17. High-resolution correlation

    NASA Astrophysics Data System (ADS)

    Nelson, D. J.

    2007-09-01

    In the basic correlation process a sequence of time-lag-indexed correlation coefficients are computed as the inner or dot product of segments of two signals. The time-lag(s) for which the magnitude of the correlation coefficient sequence is maximized is the estimated relative time delay of the two signals. For discrete sampled signals, the delay estimated in this manner is quantized with the same relative accuracy as the clock used in sampling the signals. In addition, the correlation coefficients are real if the input signals are real. There have been many methods proposed to estimate signal delay to more accuracy than the sample interval of the digitizer clock, with some success. These methods include interpolation of the correlation coefficients, estimation of the signal delay from the group delay function, and beam forming techniques, such as the MUSIC algorithm. For spectral estimation, techniques based on phase differentiation have been popular, but these techniques have apparently not been applied to the correlation problem . We propose a phase based delay estimation method (PBDEM) based on the phase of the correlation function that provides a significant improvement of the accuracy of time delay estimation. In the process, the standard correlation function is first calculated. A time lag error function is then calculated from the correlation phase and is used to interpolate the correlation function. The signal delay is shown to be accurately estimated as the zero crossing of the correlation phase near the index of the peak correlation magnitude. This process is nearly as fast as the conventional correlation function on which it is based. For real valued signals, a simple modification is provided, which results in the same correlation accuracy as is obtained for complex valued signals.

  18. Response functions for computing absorbed dose to skeletal tissues from photon irradiation—an update

    NASA Astrophysics Data System (ADS)

    Johnson, Perry B.; Bahadori, Amir A.; Eckerman, Keith F.; Lee, Choonsik; Bolch, Wesley E.

    2011-04-01

    A comprehensive set of photon fluence-to-dose response functions (DRFs) is presented for two radiosensitive skeletal tissues—active and total shallow marrow—within 15 and 32 bone sites, respectively, of the ICRP reference adult male. The functions were developed using fractional skeletal masses and associated electron-absorbed fractions as reported for the UF hybrid adult male phantom, which in turn is based upon micro-CT images of trabecular spongiosa taken from a 40 year male cadaver. The new DRFs expand upon both the original set of seven functions produced in 1985, and a 2007 update calculated under the assumption of secondary electron escape from spongiosa. In this study, it is assumed that photon irradiation of the skeleton will yield charged particle equilibrium across all spongiosa regions at energies exceeding 200 keV. Kerma coefficients for active marrow, inactive marrow, trabecular bone and spongiosa at higher energies are calculated using the DRF algorithm setting the electron-absorbed fraction for self-irradiation to unity. By comparing kerma coefficients and DRF functions, dose enhancement factors and mass energy-absorption coefficient (MEAC) ratios for active marrow to spongiosa were derived. These MEAC ratios compared well with those provided by the NIST Physical Reference Data Library (mean difference of 0.8%), and the dose enhancement factors for active marrow compared favorably with values calculated in the well-known study published by King and Spiers (1985 Br. J. Radiol. 58 345-56) (mean absolute difference of 1.9 percentage points). Additionally, dose enhancement factors for active marrow were shown to correlate well with the shallow marrow volume fraction (R2 = 0.91). Dose enhancement factors for the total shallow marrow were also calculated for 32 bone sites representing the first such derivation for this target tissue.

  19. The european organization for research and treatment of cancer quality of life questionnaire-BR 23 breast cancer-specific quality of life questionnaire: psychometric properties in a Moroccan sample of breast cancer patients

    PubMed Central

    2014-01-01

    Background Quality of life (QOL) and its measurement in cancer patients is becoming increasingly important. Breast cancer diagnosis and treatment are often associated with psychological distress and reduced QoL. In Arabic-speaking countries, QoL of patients with cancer is inadequately studied. The aim of this study was to test the reliability and validity of the Moroccan Arabic version of the European Organization for Research and Treatment of Cancer (EORTC) Breast Cancer-Specific Quality of Life Questionnaire (QLQ-BR23). Methods After translation and cross-cultural adaptation, the questionnaire was tested on breast cancer patients. The participants’ number for the test and the retest were 105 and 37 respectively. Internal consistency was tested using Cronbach’s alpha coefficient (α), the test-retest reliability using intraclass correlation coefficients (ICC). Construct validity was assessed by examining item-convergent and divergent validity. Results The questionnaire was administered to 105 patients. The mean age of patients was 48 years (SD: 16), 62.9% were married. 68.6% of all participants lived in urban area. The average time to complete the QLQ- BR23 was 15 min. Cronbach’s alpha coefficient, were all >0.7, with the exception of breast symptoms and arm symptoms. All items exceeded the 0.4 criterion for convergent validity except item 20 and 23 related to pain and skin problems in the affected breast respectively. Conclusion In general, the findings of this study indicated that the Moroccan Arabic version of the EORTC QLQ-BR23 is a reliable and valid supplementary measure of the QOL in breast cancer patients and can be used in clinical trials and studies of outcome research in oncology. PMID:24447401

  20. Response functions for computing absorbed dose to skeletal tissues from photon irradiation--an update.

    PubMed

    Johnson, Perry B; Bahadori, Amir A; Eckerman, Keith F; Lee, Choonsik; Bolch, Wesley E

    2011-04-21

    A comprehensive set of photon fluence-to-dose response functions (DRFs) is presented for two radiosensitive skeletal tissues-active and total shallow marrow-within 15 and 32 bone sites, respectively, of the ICRP reference adult male. The functions were developed using fractional skeletal masses and associated electron-absorbed fractions as reported for the UF hybrid adult male phantom, which in turn is based upon micro-CT images of trabecular spongiosa taken from a 40 year male cadaver. The new DRFs expand upon both the original set of seven functions produced in 1985, and a 2007 update calculated under the assumption of secondary electron escape from spongiosa. In this study, it is assumed that photon irradiation of the skeleton will yield charged particle equilibrium across all spongiosa regions at energies exceeding 200 keV. Kerma coefficients for active marrow, inactive marrow, trabecular bone and spongiosa at higher energies are calculated using the DRF algorithm setting the electron-absorbed fraction for self-irradiation to unity. By comparing kerma coefficients and DRF functions, dose enhancement factors and mass energy-absorption coefficient (MEAC) ratios for active marrow to spongiosa were derived. These MEAC ratios compared well with those provided by the NIST Physical Reference Data Library (mean difference of 0.8%), and the dose enhancement factors for active marrow compared favorably with values calculated in the well-known study published by King and Spiers (1985 Br. J. Radiol. 58 345-56) (mean absolute difference of 1.9 percentage points). Additionally, dose enhancement factors for active marrow were shown to correlate well with the shallow marrow volume fraction (R(2) = 0.91). Dose enhancement factors for the total shallow marrow were also calculated for 32 bone sites representing the first such derivation for this target tissue.

  1. The European Organization for Research and Treatment of Cancer quality of life questionnaire-BR23 Breast Cancer-Specific Quality of Life Questionnaire: psychometric properties in a Moroccan sample of breast cancer patients.

    PubMed

    El Fakir, Samira; Abda, Naima; Bendahhou, Karima; Zidouh, Ahmed; Bennani, Maria; Errihani, Hassan; Benider, Abdelatif; Bekkali, Rachid; Nejjari, Chakib

    2014-01-21

    Quality of life (QOL) and its measurement in cancer patients is becoming increasingly important. Breast cancer diagnosis and treatment are often associated with psychological distress and reduced QoL. In Arabic-speaking countries, QoL of patients with cancer is inadequately studied.The aim of this study was to test the reliability and validity of the Moroccan Arabic version of the European Organization for Research and Treatment of Cancer (EORTC) Breast Cancer-Specific Quality of Life Questionnaire (QLQ-BR23). After translation and cross-cultural adaptation, the questionnaire was tested on breast cancer patients. The participants' number for the test and the retest were 105 and 37 respectively. Internal consistency was tested using Cronbach's alpha coefficient (α), the test-retest reliability using intraclass correlation coefficients (ICC). Construct validity was assessed by examining item-convergent and divergent validity. The questionnaire was administered to 105 patients. The mean age of patients was 48 years (SD: 16), 62.9% were married. 68.6% of all participants lived in urban area.The average time to complete the QLQ- BR23 was 15 min. Cronbach's alpha coefficient, were all >0.7, with the exception of breast symptoms and arm symptoms. All items exceeded the 0.4 criterion for convergent validity except item 20 and 23 related to pain and skin problems in the affected breast respectively. In general, the findings of this study indicated that the Moroccan Arabic version of the EORTC QLQ-BR23 is a reliable and valid supplementary measure of the QOL in breast cancer patients and can be used in clinical trials and studies of outcome research in oncology.

  2. Development of stock correlation networks using mutual information and financial big data.

    PubMed

    Guo, Xue; Zhang, Hu; Tian, Tianhai

    2018-01-01

    Stock correlation networks use stock price data to explore the relationship between different stocks listed in the stock market. Currently this relationship is dominantly measured by the Pearson correlation coefficient. However, financial data suggest that nonlinear relationships may exist in the stock prices of different shares. To address this issue, this work uses mutual information to characterize the nonlinear relationship between stocks. Using 280 stocks traded at the Shanghai Stocks Exchange in China during the period of 2014-2016, we first compare the effectiveness of the correlation coefficient and mutual information for measuring stock relationships. Based on these two measures, we then develop two stock networks using the Minimum Spanning Tree method and study the topological properties of these networks, including degree, path length and the power-law distribution. The relationship network based on mutual information has a better distribution of the degree and larger value of the power-law distribution than those using the correlation coefficient. Numerical results show that mutual information is a more effective approach than the correlation coefficient to measure the stock relationship in a stock market that may undergo large fluctuations of stock prices.

  3. Development of stock correlation networks using mutual information and financial big data

    PubMed Central

    Guo, Xue; Zhang, Hu

    2018-01-01

    Stock correlation networks use stock price data to explore the relationship between different stocks listed in the stock market. Currently this relationship is dominantly measured by the Pearson correlation coefficient. However, financial data suggest that nonlinear relationships may exist in the stock prices of different shares. To address this issue, this work uses mutual information to characterize the nonlinear relationship between stocks. Using 280 stocks traded at the Shanghai Stocks Exchange in China during the period of 2014-2016, we first compare the effectiveness of the correlation coefficient and mutual information for measuring stock relationships. Based on these two measures, we then develop two stock networks using the Minimum Spanning Tree method and study the topological properties of these networks, including degree, path length and the power-law distribution. The relationship network based on mutual information has a better distribution of the degree and larger value of the power-law distribution than those using the correlation coefficient. Numerical results show that mutual information is a more effective approach than the correlation coefficient to measure the stock relationship in a stock market that may undergo large fluctuations of stock prices. PMID:29668715

  4. Spaced antenna diversity in temperate latitude meteor burst systems operating near 40 MHz - Variation of signal cross-correlation coefficients with antenna separation

    NASA Astrophysics Data System (ADS)

    Cannon, Paul S.; Shukla, Anil K.; Lester, Mark

    1993-04-01

    We have studied 37-MHz signals received over an 800-km temperate latitude path using 400-W continuous wave transmissions. Signals collected during a 9-day period in February 1990 on two antennas at separations of 5, 10, and 20 lambda were analyzed. Three signal categories were identified (overdense, underdense, and not known (NK)) and cross-correlation coefficients between the signals received by the two antennas were calculated for each signal category. No spatial variation, and in particular no decrease, in average cross-correlation coefficient was observed for underdense or NK signals as the antenna spacing was increased from 5 to 20 lambda. At each antenna separation the cross-correlation coefficients of these two categories were strongly dependent on time. Overdense signals, however, showed no cross-correlation time dependency at 5 and 10 lambda, but there was a strong time dependency at 20 lambda. Recommendations are made in regard to the optimum antenna spacing for a meteor burst communication system using spaced antenna diversity.

  5. Transcultural adaptation and psychometric properties of Spanish version of Pregnancy Physical Activity Questionnaire: the PregnActive project.

    PubMed

    Oviedo-Caro, Miguel Ángel; Bueno-Antequera, Javier; Munguía-Izquierdo, Diego

    2018-03-19

    To transculturally adapt the Spanish version of Pregnancy Physical Activity Questionnaire (PPAQ) analyzing its psychometric properties. The PPAQ was transculturally adapted into Spanish. Test-retest reliability was evaluated in a subsample of 109 pregnant women. The validity was evaluated in a sample of 208 pregnant women who answered the questionnaire and wore the multi-sensor monitor for 7 valid days. The reliability (intraclass correlation coefficient), concordance (concordance correlation coefficient), correlation (Pearson correlation coefficient), agreement (Bland-Altman plots) and relative activity levels (Jonckheere-Terpstra test) between both administrations and methods were examined. Intraclass correlation coefficients between both administrations were good for all categories except transportation. A low but significant correlation was found for total activity (light and above) whereas no correlation was found for other intensities between both methods. Relative activity levels analysis showed a significant linear trend for increased total activity between both methods. Spanish version of PPAQ is a brief and easily interpretable questionnaire with good reliability and ability to rank individuals, and poor validity compared with multi-sensor monitor. The use of PPAQ provides information of pregnancy-specific activities in order to establish physical activity levels of pregnant women and adapt health promotion interventions. Copyright © 2018 SESPAS. Publicado por Elsevier España, S.L.U. All rights reserved.

  6. Cross-Correlations and Structures of Aero-Engine Gas Path System Based on DCCA Coefficient and Rooted Tree

    NASA Astrophysics Data System (ADS)

    Dong, Keqiang; Fan, Jie; Gao, You

    2015-12-01

    Identifying the mutual interaction is a crucial problem that facilitates the understanding of emerging structures in complex system. We here focus on aero-engine dynamic as an example of complex system. By applying the detrended cross-correlation analysis (DCCA) coefficient method to aero-engine gas path system, we find that the low-spool rotor speed (N1) and high-spool rotor speed (N2) fluctuation series exhibit cross-correlation characteristic. Further, we employ detrended cross-correlation coefficient matrix and rooted tree to investigate the mutual interactions of other gas path variables. The results can infer that the exhaust gas temperature (EGT), N1, N2, fuel flow (WF) and engine pressure ratio (EPR) are main gas path parameters.

  7. Colocalization analysis in fluorescence micrographs: verification of a more accurate calculation of pearson's correlation coefficient.

    PubMed

    Barlow, Andrew L; Macleod, Alasdair; Noppen, Samuel; Sanderson, Jeremy; Guérin, Christopher J

    2010-12-01

    One of the most routine uses of fluorescence microscopy is colocalization, i.e., the demonstration of a relationship between pairs of biological molecules. Frequently this is presented simplistically by the use of overlays of red and green images, with areas of yellow indicating colocalization of the molecules. Colocalization data are rarely quantified and can be misleading. Our results from both synthetic and biological datasets demonstrate that the generation of Pearson's correlation coefficient between pairs of images can overestimate positive correlation and fail to demonstrate negative correlation. We have demonstrated that the calculation of a thresholded Pearson's correlation coefficient using only intensity values over a determined threshold in both channels produces numerical values that more accurately describe both synthetic datasets and biological examples. Its use will bring clarity and accuracy to colocalization studies using fluorescent microscopy.

  8. Estimation of soil-soil solution distribution coefficient of radiostrontium using soil properties.

    PubMed

    Ishikawa, Nao K; Uchida, Shigeo; Tagami, Keiko

    2009-02-01

    We propose a new approach for estimation of soil-soil solution distribution coefficient (K(d)) of radiostrontium using some selected soil properties. We used 142 Japanese agricultural soil samples (35 Andosol, 25 Cambisol, 77 Fluvisol, and 5 others) for which Sr-K(d) values had been determined by a batch sorption test and listed in our database. Spearman's rank correlation test was carried out to investigate correlations between Sr-K(d) values and soil properties. Electrical conductivity and water soluble Ca had good correlations with Sr-K(d) values for all soil groups. Then, we found a high correlation between the ratio of exchangeable Ca to Ca concentration in water soluble fraction and Sr-K(d) values with correlation coefficient R=0.72. This pointed us toward a relatively easy way to estimate Sr-K(d) values.

  9. Reducing Bias and Error in the Correlation Coefficient Due to Nonnormality.

    PubMed

    Bishara, Anthony J; Hittner, James B

    2015-10-01

    It is more common for educational and psychological data to be nonnormal than to be approximately normal. This tendency may lead to bias and error in point estimates of the Pearson correlation coefficient. In a series of Monte Carlo simulations, the Pearson correlation was examined under conditions of normal and nonnormal data, and it was compared with its major alternatives, including the Spearman rank-order correlation, the bootstrap estimate, the Box-Cox transformation family, and a general normalizing transformation (i.e., rankit), as well as to various bias adjustments. Nonnormality caused the correlation coefficient to be inflated by up to +.14, particularly when the nonnormality involved heavy-tailed distributions. Traditional bias adjustments worsened this problem, further inflating the estimate. The Spearman and rankit correlations eliminated this inflation and provided conservative estimates. Rankit also minimized random error for most sample sizes, except for the smallest samples ( n = 10), where bootstrapping was more effective. Overall, results justify the use of carefully chosen alternatives to the Pearson correlation when normality is violated.

  10. Reducing Bias and Error in the Correlation Coefficient Due to Nonnormality

    PubMed Central

    Hittner, James B.

    2014-01-01

    It is more common for educational and psychological data to be nonnormal than to be approximately normal. This tendency may lead to bias and error in point estimates of the Pearson correlation coefficient. In a series of Monte Carlo simulations, the Pearson correlation was examined under conditions of normal and nonnormal data, and it was compared with its major alternatives, including the Spearman rank-order correlation, the bootstrap estimate, the Box–Cox transformation family, and a general normalizing transformation (i.e., rankit), as well as to various bias adjustments. Nonnormality caused the correlation coefficient to be inflated by up to +.14, particularly when the nonnormality involved heavy-tailed distributions. Traditional bias adjustments worsened this problem, further inflating the estimate. The Spearman and rankit correlations eliminated this inflation and provided conservative estimates. Rankit also minimized random error for most sample sizes, except for the smallest samples (n = 10), where bootstrapping was more effective. Overall, results justify the use of carefully chosen alternatives to the Pearson correlation when normality is violated. PMID:29795841

  11. A Perceptually Weighted Rank Correlation Indicator for Objective Image Quality Assessment

    NASA Astrophysics Data System (ADS)

    Wu, Qingbo; Li, Hongliang; Meng, Fanman; Ngan, King N.

    2018-05-01

    In the field of objective image quality assessment (IQA), the Spearman's $\\rho$ and Kendall's $\\tau$ are two most popular rank correlation indicators, which straightforwardly assign uniform weight to all quality levels and assume each pair of images are sortable. They are successful for measuring the average accuracy of an IQA metric in ranking multiple processed images. However, two important perceptual properties are ignored by them as well. Firstly, the sorting accuracy (SA) of high quality images are usually more important than the poor quality ones in many real world applications, where only the top-ranked images would be pushed to the users. Secondly, due to the subjective uncertainty in making judgement, two perceptually similar images are usually hardly sortable, whose ranks do not contribute to the evaluation of an IQA metric. To more accurately compare different IQA algorithms, we explore a perceptually weighted rank correlation indicator in this paper, which rewards the capability of correctly ranking high quality images, and suppresses the attention towards insensitive rank mistakes. More specifically, we focus on activating `valid' pairwise comparison towards image quality, whose difference exceeds a given sensory threshold (ST). Meanwhile, each image pair is assigned an unique weight, which is determined by both the quality level and rank deviation. By modifying the perception threshold, we can illustrate the sorting accuracy with a more sophisticated SA-ST curve, rather than a single rank correlation coefficient. The proposed indicator offers a new insight for interpreting visual perception behaviors. Furthermore, the applicability of our indicator is validated in recommending robust IQA metrics for both the degraded and enhanced image data.

  12. [Impact of air pollution in paediatric consultations in Primary Health Care: Ecological study].

    PubMed

    Martín Martín, Raquel; Sánchez Bayle, Marciano

    2017-08-09

    To study the correlation between the levels of environmental pollutants and the number of paediatric consultations related to respiratory disease in Primary Health Care. An ecological study is performed, in which the dependent variable analysed was the number of paediatric consultations in an urban Primary Health Care centre in Madrid over a 3 year period (2013-2015), and specifically the consultations related to bronchiolitis, recurrent bronchospasm, and upper respiratory diseases. The independent variables analysed were the levels of environmental pollutants. Coefficients of correlation and multiple lineal regressions were calculated. An analysis has been carried out comparing the average of paediatric consultations when the levels of nitrogen dioxide (NO 2 ) were higher and lower than 40μg/m 3. RESULTS: During the period of the study, there were a total of 52,322 paediatric consultations in the health centre, of which 6,473 (12.37%) were related to respiratory diseases. A positive correlation was found between SO 2 , CO, NOx and NO 2 and benzene levels and paediatric consultations related to respiratory diseases, and a negative correlation with temperature. The number of consultations was significantly higher when NO 2 levels exceeded 40μg/m 3 . In the multiple lineal regression (P=.0001), the correlation was only positive between consultations and NO 2 levels (3.630, 95% CI: 0.691-6.570), and negative with temperature (-5,957, 95% CI: -8.665 to -3.248). NO 2 environmental pollution is related to an increase in respiratory diseases in children. Paediatricians should contribute to promote an improvement in urban air quality as a significant preventive measure. Copyright © 2017. Publicado por Elsevier España, S.L.U.

  13. Macroscopic Violation of Three Cauchy-Schwarz Inequalities Using Correlated Light Beams From an Infra-Red Emitting Semiconductor Diode Array

    NASA Technical Reports Server (NTRS)

    Edwards, P. J.; Huang, X.; Li, Y. Q. (Editor); Wang, Y. Z. (Editor)

    1996-01-01

    We briefly review quantum mechanical and semi-classical descriptions of experiments which demonstrate the macroscopic violation of the three Cauchy-Schwarz inequalities: g(sup 2)(sub 11)(0) greater than or equal to 1; g(sup 2)(sub 11)(0) greater than or equal to g(sup 2)(sub 11)(t), (t approaches infinity); (the absolute value of g(sup 2)(sub 11)(0))(exp 2) less than or equal to g(sup 2)(sub 11)(0) g(sup 2)(sub 11)(0). Our measurements demonstrate the violation, at macroscopic intensities, of each of these inequalities. We show that their violation, although weak, can be demonstrated through photodetector current covariance measurements on correlated sub-Poissonian Poissonian, and super Poissonian light beams. Such beams are readily generated by a tandem array of infrared-emitting semiconductor junction diodes. Our measurements utilize an electrically coupled array of one or more infrared-emitting diodes, optically coupled to a detector array. The emitting array is operated in such a way as to generate highly correlated beams of variable photon Fano Factor. Because the measurements are made on time scales long compared with the first order coherence time and with detector areas large compared with the corresponding coherence areas, first order interference effects are negligible. The first and second inequalities are violated, as expected, when a sub-Poissonian light beam is split and the intensity fluctuations of the two split beams are measured by two photodetectors and subsequently cross-correlated. The third inequality is violated by bunched (as well as anti-bunched) beams of equal intensity provided the measured cross correlation coefficient exceeds (F - 1)/F, where F is the measured Fano Factor of each beam. We also investigate the violation for the case of unequal beams.

  14. Correlation and prediction of gaseous diffusion coefficients.

    NASA Technical Reports Server (NTRS)

    Marrero, T. R.; Mason, E. A.

    1973-01-01

    A new correlation method for binary gaseous diffusion coefficients from very low temperatures to 10,000 K is proposed based on an extended principle of corresponding states, and having greater range and accuracy than previous correlations. There are two correlation parameters that are related to other physical quantities and that are predictable in the absence of diffusion measurements. Quantum effects and composition dependence are included, but high-pressure effects are not. The results are directly applicable to multicomponent mixtures.

  15. Equations of prediction for abdominal fat in brown egg-laying hens fed different diets.

    PubMed

    Souza, C; Jaimes, J J B; Gewehr, C E

    2017-06-01

    The objective was to use noninvasive measurements to formulate equations for predicting the abdominal fat weight of laying hens in a noninvasive manner. Hens were fed with different diets; the external body measurements of birds were used as regressors. We used 288 Hy-Line Brown laying hens, distributed in a completely randomized design in a factorial arrangement, submitted for 16 wk to 2 metabolizable energy levels (2,550 and 2,800 kcal/kg) and 3 levels of crude protein in the diet (150, 160, and 170 g/kg), totaling 6 treatments, with 48 hens each. Sixteen hens per treatment of 92 wk age were utilized to evaluate body weight, bird length, tarsus and sternum, greater and lesser diameter of the tarsus, and abdominal fat weight, after slaughter. The equations were obtained by using measures evaluated with regressors through simple and multiple linear regression with the stepwise method of indirect elimination (backward), with P < 0.10 for all variables remaining in the model. The weight of abdominal fat as predicted by the equations and observed values for each bird were subjected to Pearson's correlation analysis. The equations generated by energy levels showed coefficients of determination of 0.50 and 0.74 for 2,800 and 2,550 kcal/kg of metabolizable energy, respectively, with correlation coefficients of 0.71 and 0.84, with a highly significant correlation between the calculated and observed values of abdominal fat. For protein levels of 150, 160, and 170 g/kg in the diet, it was possible to obtain coefficients of determination of 0.75, 0.57, and 0.61, with correlation coefficients of 0.86, 0.75, and 0.78, respectively. Regarding the general equation for predicting abdominal fat weight, the coefficient of determination was 0.62; the correlation coefficient was 0.79. The equations for predicting abdominal fat weight in laying hens, based on external measurements of the birds, showed positive coefficients of determination and correlation coefficients, thus allowing researchers to determine abdominal fat weight in vivo. © 2016 Poultry Science Association Inc.

  16. Depression, stress, and blood pressure in urban African-American women.

    PubMed

    Artinian, Nancy T; Washington, Olivia G M; Flack, John M; Hockman, Elaine M; Jen, Kai-Lin Catherine

    2006-01-01

    African-American women have disturbingly high rates of hypertension, exceeding those of African-American men and other ethnic groups. Reasons for these disparities are not understood. Depression, more common in women than men, has been linked to endothelial dysfunction, inflammation, metabolic and hematologic abnormalities, and increased sympathetic nervous system activity--all factors associated with cardiovascular disease. A descriptive correlational design was used to test the following hypotheses: 1) African-American women with higher levels of depression will have higher blood pressure (BP) levels, more cardiovascular risk factors, greater stress, and lower social support; and 2) depression will mediate the relationship between stress and BP. A convenience sample of 245 hypertensive African-American women (mean age, 61+/-12.7 years) was recruited through free BP screenings offered in the community. All data were collected during a structured interview and brief physical examination. Pearson r correlation coefficients, analysis of variance, and multiple regression analyses were used to analyze the hypotheses. Women with higher levels of depression had higher diastolic BP and were more likely to smoke, eat fewer fruits and vegetables, and have more stress and less social support. Depression mediated the relationship between stress and diastolic BP. The findings emphasize the importance of assessing both behavioral and psychosocial factors in urban African-American women with hypertension.

  17. The comparison of high and standard definition computed tomography techniques regarding coronary artery imaging.

    PubMed

    Aykut, Aktas; Bumin, Degirmenci; Omer, Yilmaz; Mustafa, Kayan; Meltem, Cetin; Orhan, Celik; Nisa, Unlu; Hikmet, Orhan; Hakan, Demirtas; Mert, Koroglu

    2015-09-01

    The aim was to compare coronary high-definition CT (HDCT) with standard-definition CT (SDCT) angiography as to radiation dose, image quality and accuracy. 28 patients with history of coronary artery disease scanned by HDCT (Discovery CT750 HD) and SDCT (Somatom Definition AS). The scan modes were both axial prospective ECG-triggered. The vessel diameters and vessel attenuation values of totally 280 measurements from 140 coronary arteries were analyzed by two experienced radiologists. All data was analyzed by intraclass correlation test. Image quality graded by motion and stair step artifacts (grade 1, poor, to grade 4, excellent), accuracy of vessel inner and outer diameters were compared between the two CT units using the independent samples t-test and Mann-Whitney U test. The intraclass correlation coefficient (ICC) of measured vessel attenuation values in SDCT between the two radiologists was exceedingly good. The ICC was higher in HDCT. The radiation dose of HDCT was higher than that of SDCT. The mean tube current was 180 (mA) in HDCT and 147(mA) in SDCT with the same tube voltage (kVp). There was no significant difference between image quality. HDCT has a higher radiation dose but has much more atenuation and the spatial resolution which improve measurement accuracy for imaging coronary arteries.

  18. Altimetric signal and three-dimensional structure of the sea in the Channel of Sicily

    NASA Astrophysics Data System (ADS)

    Nardelli, Bruno Buongiorno; Santoleri, Rosalia; Iudicone, Daniele; Zoffoli, Simona; Marullo, Salvatore

    1999-09-01

    The 1996 Altimeter/Synoptic Mesoscale Plancton Experiment (ALT/SYMPLEX) was specifically designed to perform in situ measurements simultaneous with the passage of TOPEX/POSEIDON (T/P) and ERS 2 over selected tracks in the central and eastern Sicily Channel. This experiment made it possible to have, for the first time, a validation of altimetry with in situ data over the Mediterranean, where weak dynamics results in a modest sea elevation, rarely exceeding 10 cm. Historical infrared and altimetric satellite data were first analyzed in order to study the variability of the circulation in the area. The comparative and integrative analysis of simultaneous satellite data and in situ measurements permitted investigation of the relation between the altimeter-derived surface topography and the three-dimensional structure of the sea. The Pearson correlation coefficients between altimeter data and dynamic heights along track resulted to be 0.72-0.89 (T/P) and 0.88 (ERS 2) when using conventional repeat track analysis. For T/P, a correlation value of 0.87 was found for time differences computed basing on a collinear analysis technique. This analysis also led to the identification of a strong barotropic component of the velocity field located near the Sicilian continental shelf, where it is responsible for approximately 60% of the signal.

  19. Virial Coefficients for the Liquid Argon

    NASA Astrophysics Data System (ADS)

    Korth, Micheal; Kim, Saesun

    2014-03-01

    We begin with a geometric model of hard colliding spheres and calculate probability densities in an iterative sequence of calculations that lead to the pair correlation function. The model is based on a kinetic theory approach developed by Shinomoto, to which we added an interatomic potential for argon based on the model from Aziz. From values of the pair correlation function at various values of density, we were able to find viral coefficients of liquid argon. The low order coefficients are in good agreement with theoretical hard sphere coefficients, but appropriate data for argon to which these results might be compared is difficult to find.

  20. 14 CFR 23.493 - Braked roll conditions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... and ground contacts must be those described in § 23.479 for level landings. (c) A drag reaction equal to the vertical reaction at the wheel multiplied by a coefficient of friction of 0.8 must be applied at the ground contact point of each wheel with brakes, except that the drag reaction need not exceed...

  1. 14 CFR 23.493 - Braked roll conditions.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... and ground contacts must be those described in § 23.479 for level landings. (c) A drag reaction equal to the vertical reaction at the wheel multiplied by a coefficient of friction of 0.8 must be applied at the ground contact point of each wheel with brakes, except that the drag reaction need not exceed...

  2. Reproducibility of food consumption frequencies derived from the Children's Eating Habits Questionnaire used in the IDEFICS study.

    PubMed

    Lanfer, A; Hebestreit, A; Ahrens, W; Krogh, V; Sieri, S; Lissner, L; Eiben, G; Siani, A; Huybrechts, I; Loit, H-M; Papoutsou, S; Kovács, E; Pala, V

    2011-04-01

    To investigate the reproducibility of food consumption frequencies derived from the food frequency section of the Children's Eating Habits Questionnaire (CEHQ-FFQ) that was developed and used in the IDEFICS (Identification and prevention of dietary- and lifestyle-induced health effects in children and infants) project to assess food habits in 2- to 9-year-old European children. From a subsample of 258 children who participated in the IDEFICS baseline examination, parental questionnaires of the CEHQ were collected twice to assess reproducibility of questionnaire results from 0 to 354 days after the first examination. Weighted Cohen's kappa coefficients (κ) and Spearman's correlation coefficients (r) were calculated to assess agreement between the first and second questionnaires for each food item of the CEHQ-FFQ. Stratification was performed for sex, age group, geographical region and length of period between the first and second administrations. Fisher's Z transformation was applied to test correlation coefficients for significant differences between strata. For all food items analysed, weighted Cohen's kappa coefficients (κ) and Spearman's correlation coefficients (r) were significant and positive (P<0.001). Reproducibility was lowest for diet soft drinks (κ=0.23, r=0.32) and highest for sweetened milk (κ=0.68, r=0.76). Correlation coefficients were comparable to those of previous studies on FFQ reproducibility in children and adults. Stratification did not reveal systematic differences in reproducibility by sex and age group. Spearman's correlation coefficients differed significantly between northern and southern European countries for 10 food items. In nine of them, the lower respective coefficient was still high enough to conclude acceptable reproducibility. As expected, longer time (>128 days) between the first and second administrations resulted in a generally lower, yet still acceptable, reproducibility. Results indicate that the CEHQ-FFQ gives reproducible estimates of the consumption frequency of 43 food items from 14 food groups in European children.

  3. [Cross-cultural adaptation and validation of the Health and Taste Attitude Scale (HTAS) in Portuguese].

    PubMed

    Koritar, Priscila; Philippi, Sonia Tucunduva; Alvarenga, Marle dos Santos; Santos, Bernardo dos

    2014-08-01

    The scope of this study was to show the cross-cultural adaptation and validation of the Health and Taste Attitude Scale in Portuguese. The methodology included translation of the scale; evaluation of conceptual, operational and item-based equivalence by 14 experts and 51 female undergraduates; semantic equivalence and measurement assessment by 12 bilingual women by the paired t-test, the Pearson correlation coefficient and the coefficient intraclass correlation; internal consistency and test-retest reliability by Cronbach's alpha and intraclass correlation coefficient, respectively, after application on 216 female undergraduates; assessment of discriminant and concurrent validity via the t-test and Spearman's correlation coefficient, respectively, in addition to Confirmatory Factor and Exploratory Factor Analysis. The scale was considered adequate and easily understood by the experts and university students and presented good internal consistency and reliability (µ 0.86, ICC 0.84). The results show that the scale is valid and can be used in studies with women to better understand attitudes related to taste.

  4. Negative Correlation between the Diffusion Coefficient and Transcriptional Activity of the Glucocorticoid Receptor.

    PubMed

    Mikuni, Shintaro; Yamamoto, Johtaro; Horio, Takashi; Kinjo, Masataka

    2017-08-25

    The glucocorticoid receptor (GR) is a transcription factor, which interacts with DNA and other cofactors to regulate gene transcription. Binding to other partners in the cell nucleus alters the diffusion properties of GR. Raster image correlation spectroscopy (RICS) was applied to quantitatively characterize the diffusion properties of EGFP labeled human GR (EGFP-hGR) and its mutants in the cell nucleus. RICS is an image correlation technique that evaluates the spatial distribution of the diffusion coefficient as a diffusion map. Interestingly, we observed that the averaged diffusion coefficient of EGFP-hGR strongly and negatively correlated with its transcriptional activities in comparison to that of EGFP-hGR wild type and mutants with various transcriptional activities. This result suggests that the decreasing of the diffusion coefficient of hGR was reflected in the high-affinity binding to DNA. Moreover, the hyper-phosphorylation of hGR can enhance the transcriptional activity by reduction of the interaction between the hGR and the nuclear corepressors.

  5. Comprehensive analysis of correlation coefficients estimated from pooling heterogeneous microarray data

    PubMed Central

    2013-01-01

    Background The synthesis of information across microarray studies has been performed by combining statistical results of individual studies (as in a mosaic), or by combining data from multiple studies into a large pool to be analyzed as a single data set (as in a melting pot of data). Specific issues relating to data heterogeneity across microarray studies, such as differences within and between labs or differences among experimental conditions, could lead to equivocal results in a melting pot approach. Results We applied statistical theory to determine the specific effect of different means and heteroskedasticity across 19 groups of microarray data on the sign and magnitude of gene-to-gene Pearson correlation coefficients obtained from the pool of 19 groups. We quantified the biases of the pooled coefficients and compared them to the biases of correlations estimated by an effect-size model. Mean differences across the 19 groups were the main factor determining the magnitude and sign of the pooled coefficients, which showed largest values of bias as they approached ±1. Only heteroskedasticity across the pool of 19 groups resulted in less efficient estimations of correlations than did a classical meta-analysis approach of combining correlation coefficients. These results were corroborated by simulation studies involving either mean differences or heteroskedasticity across a pool of N > 2 groups. Conclusions The combination of statistical results is best suited for synthesizing the correlation between expression profiles of a gene pair across several microarray studies. PMID:23822712

  6. Urinary metabolite levels and symptoms in Filipino workers using organic solvents.

    PubMed

    Cucueco, M T; Espinosa, N C; Villanueva, M B; Castro, F T; Sison, S Y; Ortega, V S; Hisanaga, N

    1993-01-01

    To compare symptoms with urinary metabolite levels, 900 workers from 7 organic solvent-using industries were studied. Urinary metabolites were determined using a high performance liquid chromatograph. Urinary hippuric acid concentrations exceeding the reference value (2.5 g/g creatinine) were found in 78 (8.7%) workers. However, only 3 (0.3%) and 1 (0.1%) of the participants exceeded the reference value for mandelic (0.8 g/g creatinine) and total methylhippuric acid (1.5 g/g creatinine), respectively. The sum of the values of the ratio of measured urinary metabolite concentration to the corresponding ACGIH's biological exposure indices (BEI) [(HA/BEI of HA + MHA/BEI of MHA + MA/BEI of MA)] exceeded 1.0 in 166 (18.4%) workers. Majority of them were from the footwear manufacturing industry (63/129 or 49.2%). Questionnaire interviews were also administered to determine the prevalence of symptoms while at work (acute symptoms) or within the past 6 months (chronic symptoms). Urinary metabolite levels of individual and mixed solvents were compared with the symptoms of all workers. Analysis using Spearman's rank correlation showed in workers whose urinary hippuric acid exceeded 3.75 g/g creatine (1.5 x BEI), significant correlation between their hippuric acid levels and subjective complaints. Workers whose sum of the values of the ratio of measured urinary metabolite concentration to corresponding BEI exceeded 1.5 were selected and comparing this level with their symptoms, significant correlation was also noted in some complaints.

  7. Reliability and validity of lumbar and abdominal trunk muscle endurance tests in office workers with nonspecific subacute low back pain.

    PubMed

    del Pozo-Cruz, Borja; Mocholi, Miguel H; del Pozo-Cruz, Jesus; Parraca, Jose A; Adsuar, Jose C; Gusi, Narcis

    2014-01-01

    Despite the widespread use of trunk endurance tests, the reliability and validity of these tests in office workers with subacute nonspecific low back pain are unknown. This cross-sectional study involved 190 subjects: 30 men and 42 women without low back pain and 47 men and 71 women with low back pain. All subjects underwent timed prone and supine isometric lumbar and abdominal trunk endurance tests that were performed until subjective fatigue occurred. All subjects also completed the Roland Morris and Oswestry self-reported disability questionnaires. A test-retest study (7 days) was conducted with 31 participants with low back pain from the study. For the abdominal trunk endurance test, males and females with low back pain had mean (SD) values of 62.06 (36.87) and 46.06 (29.28) seconds, respectively, both significantly lower than the asymptomatic workers. For the lumbar test, males and females with low back pain had mean (SD) values of 79.57 (30.66) and 75.49 (28.97) seconds, respectively, again, both significantly lower than the asymptomatic workers. The intraclass correlation coefficients of both tests exceeded 0.90 and the Kappa indices were excellent for both men and women. Receiver-operating curve analyses revealed areas under the curve very close to or exceeding 0.70 for both men and women for both tests. The lumbar and abdominal trunk muscle endurance tests appeared to be reliable and valid measures in office workers with subacute low back pain.

  8. Evaluating Shielding Effectiveness for Reducing Space Radiation Cancer Risks

    NASA Technical Reports Server (NTRS)

    Cucinotta, Francis A.; Kim, Myung-Hee Y.; Ren, Lei

    2007-01-01

    We discuss calculations of probability distribution functions (PDF) representing uncertainties in projecting fatal cancer risk from galactic cosmic rays (GCR) and solar particle events (SPE). The PDF s are used in significance tests of the effectiveness of potential radiation shielding approaches. Uncertainties in risk coefficients determined from epidemiology data, dose and dose-rate reduction factors, quality factors, and physics models of radiation environments are considered in models of cancer risk PDF s. Competing mortality risks and functional correlations in radiation quality factor uncertainties are treated in the calculations. We show that the cancer risk uncertainty, defined as the ratio of the 95% confidence level (CL) to the point estimate is about 4-fold for lunar and Mars mission risk projections. For short-stay lunar missions (<180 d), SPE s present the most significant risk, however one that is mitigated effectively by shielding, especially for carbon composites structures with high hydrogen content. In contrast, for long duration lunar (>180 d) or Mars missions, GCR risks may exceed radiation risk limits, with 95% CL s exceeding 10% fatal risk for males and females on a Mars mission. For reducing GCR cancer risks, shielding materials are marginally effective because of the penetrating nature of GCR and secondary radiation produced in tissue by relativistic particles. At the present time, polyethylene or carbon composite shielding can not be shown to significantly reduce risk compared to aluminum shielding based on a significance test that accounts for radiobiology uncertainties in GCR risk projection.

  9. Correlation between National Influenza Surveillance Data and Google Trends in South Korea

    PubMed Central

    Jo, Min Woo; Shin, Soo-Yong; Lee, Jae Ho; Ryoo, Seoung Mok; Kim, Won Young; Seo, Dong-Woo

    2013-01-01

    Background In South Korea, there is currently no syndromic surveillance system using internet search data, including Google Flu Trends. The purpose of this study was to investigate the correlation between national influenza surveillance data and Google Trends in South Korea. Methods Our study was based on a publicly available search engine database, Google Trends, using 12 influenza-related queries, from September 9, 2007 to September 8, 2012. National surveillance data were obtained from the Korea Centers for Disease Control and Prevention (KCDC) influenza-like illness (ILI) and virologic surveillance system. Pearson's correlation coefficients were calculated to compare the national surveillance and the Google Trends data for the overall period and for 5 influenza seasons. Results The correlation coefficient between the KCDC ILI and virologic surveillance data was 0.72 (p<0.05). The highest correlation was between the Google Trends query of H1N1 and the ILI data, with a correlation coefficient of 0.53 (p<0.05), for the overall study period. When compared with the KCDC virologic data, the Google Trends query of bird flu had the highest correlation with a correlation coefficient of 0.93 (p<0.05) in the 2010-11 season. The following queries showed a statistically significant correlation coefficient compared with ILI data for three consecutive seasons: Tamiflu (r = 0.59, 0.86, 0.90, p<0.05), new flu (r = 0.64, 0.43, 0.70, p<0.05) and flu (r = 0.68, 0.43, 0.77, p<0.05). Conclusions In our study, we found that the Google Trends for certain queries using the survey on influenza correlated with national surveillance data in South Korea. The results of this study showed that Google Trends in the Korean language can be used as complementary data for influenza surveillance but was insufficient for the use of predictive models, such as Google Flu Trends. PMID:24339927

  10. Correlation between national influenza surveillance data and google trends in South Korea.

    PubMed

    Cho, Sungjin; Sohn, Chang Hwan; Jo, Min Woo; Shin, Soo-Yong; Lee, Jae Ho; Ryoo, Seoung Mok; Kim, Won Young; Seo, Dong-Woo

    2013-01-01

    In South Korea, there is currently no syndromic surveillance system using internet search data, including Google Flu Trends. The purpose of this study was to investigate the correlation between national influenza surveillance data and Google Trends in South Korea. Our study was based on a publicly available search engine database, Google Trends, using 12 influenza-related queries, from September 9, 2007 to September 8, 2012. National surveillance data were obtained from the Korea Centers for Disease Control and Prevention (KCDC) influenza-like illness (ILI) and virologic surveillance system. Pearson's correlation coefficients were calculated to compare the national surveillance and the Google Trends data for the overall period and for 5 influenza seasons. The correlation coefficient between the KCDC ILI and virologic surveillance data was 0.72 (p<0.05). The highest correlation was between the Google Trends query of H1N1 and the ILI data, with a correlation coefficient of 0.53 (p<0.05), for the overall study period. When compared with the KCDC virologic data, the Google Trends query of bird flu had the highest correlation with a correlation coefficient of 0.93 (p<0.05) in the 2010-11 season. The following queries showed a statistically significant correlation coefficient compared with ILI data for three consecutive seasons: Tamiflu (r = 0.59, 0.86, 0.90, p<0.05), new flu (r = 0.64, 0.43, 0.70, p<0.05) and flu (r = 0.68, 0.43, 0.77, p<0.05). In our study, we found that the Google Trends for certain queries using the survey on influenza correlated with national surveillance data in South Korea. The results of this study showed that Google Trends in the Korean language can be used as complementary data for influenza surveillance but was insufficient for the use of predictive models, such as Google Flu Trends.

  11. Supersymmetric contributions to weak decay correlation coefficients

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Profumo, S.; Ramsey-Musolf, M. J.; Tulin, S.

    2007-04-01

    We study supersymmetric contributions to correlation coefficients that characterize the spectral shape and angular distribution for polarized {mu}- and {beta}-decays. In the minimal supersymmetric standard model (MSSM), one-loop box graphs containing superpartners can give rise to non-(V-Ax(V-A) four-fermion operators in the presence of left-right or flavor mixing between sfermions. We analyze the present phenomenological constraints on such mixing and determine the range of allowed contributions to the weak decay correlation coefficients. We discuss the prospective implications for future {mu}- and {beta}-decay experiments, and argue that they may provide unique probes of left-right mixing in the first generation scalar fermion sector.

  12. Ecotoxicology of phenylphosphonothioates.

    PubMed Central

    Francis, B M; Hansen, L G; Fukuto, T R; Lu, P Y; Metcalf, R L

    1980-01-01

    The phenylphosphonothioate insecticides EPN and leptophos, and several analogs, were evaluated with respect to their delayed neurotoxic effects in hens and their environmental behavior in a terrestrial-aquatic model ecosystem. Acute toxicity to insects was highly correlated with sigma sigma of the substituted phenyl group (regression coefficient r = -0.91) while acute toxicity to mammals was slightly less well correlated (regression coefficient r = -0.71), and neurotoxicity was poorly correlated with sigma sigma (regression coefficient r = -0.35). Both EPN and leptophos were markedly more persistent and bioaccumulative in the model ecosystem than parathion. Desbromoleptophos, a contaminant and metabolite of leptophos, was seen to be a highly stable and persistent terminal residue of leptophos. PMID:6159210

  13. Choosing the best index for the average score intraclass correlation coefficient.

    PubMed

    Shieh, Gwowen

    2016-09-01

    The intraclass correlation coefficient (ICC)(2) index from a one-way random effects model is widely used to describe the reliability of mean ratings in behavioral, educational, and psychological research. Despite its apparent utility, the essential property of ICC(2) as a point estimator of the average score intraclass correlation coefficient is seldom mentioned. This article considers several potential measures and compares their performance with ICC(2). Analytical derivations and numerical examinations are presented to assess the bias and mean square error of the alternative estimators. The results suggest that more advantageous indices can be recommended over ICC(2) for their theoretical implication and computational ease.

  14. Affects of mining activities on Cd pollution to the paddy soils and rice grain in Hunan province, Central South China.

    PubMed

    Du, Yan; Hu, Xue-Feng; Wu, Xiao-Hong; Shu, Ying; Jiang, Ying; Yan, Xiao-Juan

    2013-12-01

    Located in Central South China, Hunan province is rich in mineral resources. To study the influence of mining on Cd pollution to local agricultural eco-system, the paddy soils and rice grain of Y county in northern Hunan province were intensively monitored. The results were as follows: (1) Total Cd (T-Cd) content in the soils of the county ranges from 0.13 to 6.02 mg kg(-1), with a mean of 0.64 mg kg(-1), of which 57.5% exceed the allowable limit specified by the China Soil Environmental Quality Standards. T-Cd in the soils varies largely, with the coefficient of variation reaching 146.4%. The spatial distribution of T-Cd in the soils quite matches with that of mining and industries. The content of HCl-extractable Cd (HCl-Cd) in the soils ranges from 0.02 to 2.17 mg kg(-1), with a mean of 0.24 mg kg(-1). A significant positive correlation exists between T-Cd and HCl-Cd in the soils (r = 0.770, ρ < 0.01). (2) Cd content in the rice produced in Y county ranges from 0.01 to 2.77 mg kg(-1), with a mean of 0.46 mg kg(-1). The rate of rice with Cd exceeding the allowable limit specified by the Chinese Grain Security Standards reaches 59.6%; that with Cd exceeding 1 mg kg(-1), called as "Cd rice," reaches 11.1%. (3) Cd content in the rice of Y county is positively significantly correlated with HCl-Cd (r = 0.177, ρ < 0.05) but not significantly with T-Cd in the soils (r = 0.091, ρ > 0.05), which suggests that the amount of Cd accumulating in the rice is more affected by its availability in the soils, rather than the total content. (4) The dietary intake of Cd via rice consumption in Y county is estimated to be 179.9 μg day(-1) person(-1) on average, which is far beyond the allowable limit specified by FAO/WHO and the target hazard quotients of Cd much higher than 1, suggesting the high risk on human health from Cd exposure.

  15. The Evolution of Pearson's Correlation Coefficient

    ERIC Educational Resources Information Center

    Kader, Gary D.; Franklin, Christine A.

    2008-01-01

    This article describes an activity for developing the notion of association between two quantitative variables. By exploring a collection of scatter plots, the authors propose a nonstandard "intuitive" measure of association; and by examining properties of this measure, they develop the more standard measure, Pearson's Correlation Coefficient. The…

  16. Modeling Concordance Correlation Coefficient for Longitudinal Study Data

    ERIC Educational Resources Information Center

    Ma, Yan; Tang, Wan; Yu, Qin; Tu, X. M.

    2010-01-01

    Measures of agreement are used in a wide range of behavioral, biomedical, psychosocial, and health-care related research to assess reliability of diagnostic test, psychometric properties of instrument, fidelity of psychosocial intervention, and accuracy of proxy outcome. The concordance correlation coefficient (CCC) is a popular measure of…

  17. Neonates with Bartter syndrome have enormous fluid and sodium requirements.

    PubMed

    Azzi, Antonio; Chehade, Hassib; Deschênes, Georges

    2015-07-01

    Managing neonatal Bartter syndrome by achieving adequate weight gain is challenging. We assessed the correlation between weight gain in neonatal Bartter syndrome and the introduction of fluid and sodium supplementations and indomethacin during the first 4 weeks of life. Daily fluid and electrolytes requirements were analysed using linear regression and Spearman correlation coefficients. The weight gain coefficient was calculated as daily weight gain after physiological neonatal weight loss. We studied seven infants. The highest weight gain coefficients occurred between weeks two and four in the five neonates who either received prompt amounts of fluid (maximum 810 mL/kg/day) and sodium (maximum 70 mmol/kg/day) or were treated with indomethacin. For the two patients with the highest weight gain coefficient, water and sodium supplementations were decreased in weeks two to four leading to a significant negative Spearman correlation between weight gain and fluid supplements (r = -0.55 and -0.68) and weight gain and sodium supplementations (r = -0.96 and -0.72). The two patients with the lowest weight gain coefficient had positive Spearman correlation coefficients between weight gain and fluid and sodium supplementations. Infants with neonatal Bartter syndrome required rapid and enormous fluid and sodium supplementations or the early introduction of indomethacin treatment to achieve adequate weight gain during the early postnatal period. ©2015 Foundation Acta Paediatrica. Published by John Wiley & Sons Ltd.

  18. Validity and Reliability of a Portable Balance Tracking System, BTrackS, in Older Adults.

    PubMed

    Levy, Susan S; Thralls, Katie J; Kviatkovsky, Shiloah A

    Falls are the leading cause of disability, injury, hospital admission, and injury-related death among older adults. Balance limitations have consistently been identified as predictors of falls and increased fall risk. Field measures of balance are limited by issues of subjectivity, ceiling effects, and low sensitivity to change. The gold standard for measuring balance is the force plate; however, its field use is untenable due to high cost and lack of portability. Thus, a critical need is observed for valid objective field measures of balance to accurately assess balance and identify limitations over time. The purpose of this study was to examine the concurrent validity and 3-day test-retest reliability of Balance Tracking System (BTrackS) in community-dwelling older adults. Minimal detectable change values were also calculated to reflect changes in balance beyond measurement error. Postural sway data were collected from community-dwelling older adults (N = 49, mean [SD] age = 71.3 [7.3] years) with a force plate and BTrackS in multitrial eyes open (EO) and eyes closed (EC) static balance conditions. Force sensors transmitted BTrackS data via a USB to a computer running custom software. Three approaches to concurrent validity were taken including calculation of Pearson product moment correlation coefficients, repeated-measures ANOVAs, and Bland-Altman plots. Three-day test-retest reliability of BTrackS was examined in a second sample of 47 community-dwelling older adults (mean [SD] age = 75.8 [7.7] years) using intraclass correlation coefficients and MDC values at 95% CI (MDC95) were calculated. BTrackS demonstrated good validity using Pearson product moment correlations (r > 0.90). Repeated-measures ANOVA and Bland-Altman plots indicated some BTrackS bias with center of pressure (COP) values higher than FP COP values in the EO (mean [SD] bias = 4.0 [6.8]) and EC (mean [SD] bias = 9.6 [12.3]) conditions. Test-retest reliability using intraclass correlation coefficients (ICC2.1 was excellent (0.83) and calculated MDC95 for EO (9.6 cm) and EC (19.4 cm) and suggested that postural sway changes of these amounts are meaningful. BTrackS showed some bias with values exceeding force plate values in both EO and EC conditions. Excellent test-retest reliability and resulting MDC95 values indicated that BTrackS has the potential to identify meaningful changes in balance that may warrant intervention. BTrackS is an objective measure of balance that can be used to monitor balance in community-dwelling older adults over time. It can reliably identify changes that may require further attention (eg, fall-prevention strategies, declines in physical function) and shows promise for assessing intervention efficacy in this growing segment of the population.

  19. [The appraisal of reliability and validity of subjective workload assessment technique and NASA-task load index].

    PubMed

    Xiao, Yuan-mei; Wang, Zhi-ming; Wang, Mian-zhen; Lan, Ya-jia

    2005-06-01

    To test the reliability and validity of two mental workload assessment scales, i.e. subjective workload assessment technique (SWAT) and NASA task load index (NASA-TLX). One thousand two hundred and sixty-eight mental workers were sampled from various kinds of occupations, such as scientific research, education, administration and medicine, etc, with randomized cluster sampling. The re-test reliability, split-half reliability, Cronbach's alpha coefficient and correlation coefficients between item score and total score were adopted to test the reliability. The test of validity included structure validity. The re-test reliability coefficients of these two scales and their items were ranged from 0.516 to 0.753 (P < 0.01), indicating the two scales had good re-test reliability; the split-half reliability of SWAT was 0.645, and its Cronbach's alpha coefficient was more than 0.80, all the correlation coefficients between its items score and total score were more than 0.70; as for NASA-TLX, both the split-half reliability and Cronbach's alpha coefficient were more than 0.80, the correlation coefficients between its items score and total score were all more than 0.60 (P < 0.01) except the item of performance. Both scales had good inner consistency. The Pearson correlation coefficient between the two scales was 0.492 (P < 0.01), implying the results of the two scales had good consistency. Factor analysis showed that the two scales had good structure validity. Both SWAT and NASA-TLX have good reliability and validity and may be used as a valid tool to assess mental workload in China after being revised properly.

  20. Pharmaceuticals' sorptions relative to properties of thirteen different soils.

    PubMed

    Kodešová, Radka; Grabic, Roman; Kočárek, Martin; Klement, Aleš; Golovko, Oksana; Fér, Miroslav; Nikodem, Antonín; Jakšík, Ondřej

    2015-04-01

    Transport of human and veterinary pharmaceuticals in soils and consequent ground-water contamination are influenced by many factors, including compound sorption on soil particles. Here we evaluate the sorption isotherms for 7 pharmaceuticals on 13 soils, described by Freundlich equations, and assess the impact of soil properties on various pharmaceuticals' sorption on soils. Sorption of ionizable pharmaceuticals was, in many cases, highly affected by soil pH. The sorption coefficient of sulfamethoxazole was negatively correlated to soil pH, and thus positively related to hydrolytic acidity and exchangeable acidity. Sorption coefficients for clindamycin and clarithromycin were positively related to soil pH and thus negatively related to hydrolytic acidity and exchangeable acidity, and positively related to base cation saturation. The sorption coefficients for the remaining pharmaceuticals (trimethoprim, metoprolol, atenolol, and carbamazepine) were also positively correlated with the base cation saturation and cation exchange capacity. Positive correlations between sorption coefficients and clay content were found for clindamycin, clarithromycin, atenolol, and metoprolol. Positive correlations between sorption coefficients and organic carbon content were obtained for trimethoprim and carbamazepine. Pedotransfer rules for predicting sorption coefficients of various pharmaceuticals included hydrolytic acidity (sulfamethoxazole), organic carbon content (trimethoprimand carbamazepine), base cation saturation (atenolol and metoprolol), exchangeable acidity and clay content (clindamycin), and soil active pH and clay content (clarithromycin). Pedotransfer rules, predicting the Freundlich sorption coefficients, could be applied for prediction of pharmaceutical mobility in soils with similar soil properties. Predicted sorption coefficients together with pharmaceutical half-lives and other imputes (e.g., soil-hydraulic, geological, hydro-geological, climatic) may be used for assessing potential ground-water contamination. Copyright © 2014 Elsevier B.V. All rights reserved.

  1. Comparing fist size to heart size is not a viable technique to assess cardiomegaly.

    PubMed

    Ampanozi, Garyfalia; Krinke, Eileen; Laberke, Patrick; Schweitzer, Wolf; Thali, Michael J; Ebert, Lars C

    2018-05-07

    Several medical textbooks state that a human heart is approximately the size of that person's fist. Stating that a heart has the size of the corpse's fist is thought to signify that the heart size is normal. We formulate two hypotheses that are tested in this article. First, we hypothesize that in cases without cardiomegaly, volumes of the hand and the heart are not significantly different. Second, we hypothesize that in cases of cardiomegaly, the heart volume statistically significantly exceeds that of the hand. We retrospectively reviewed 130 consecutive postmortem computed tomography datasets from the BLINDED starting from 01/01/2013, covering a period of approximately 3 months. Hands and hearts were segmented and their volumes estimated. We obtained the following information from the postmortem examination reports: age, sex, body length and weight, heart weight, cardiomegaly, and cause of death. When exploring the correlation between mean hand volume and heart volume, only in the group of the females with cardiomegaly (N=8) could a positive, statistically significant correlation be ascertained (Pearson correlation coefficient 0.753, P=.031). In this study, we demonstrated that the commonly used idea that a heart larger than the fist of a patient suggests cardiomegaly might be incorrect. Because this perception is commonly used in autopsy reports, it might lead to avoidable errors. Until further studies confirm this hypothesis, this informal measurement should no longer be taught or used. Copyright © 2018 Elsevier Inc. All rights reserved.

  2. Atomic-scale dynamics of a model glass-forming metallic liquid: Dynamical crossover, dynamical decoupling, and dynamical clustering

    DOE PAGES

    Jaiswal, Abhishek; Egami, Takeshi; Zhang, Yang

    2015-04-01

    The phase behavior of multi-component metallic liquids is exceedingly complex because of the convoluted many-body and many-elemental interactions. Herein, we present systematic studies of the dynamic aspects of such a model ternary metallic liquid Cu 40Zr 51Al 9 using molecular dynamics simulation with embedded atom method. We observed a dynamical crossover from Arrhenius to super-Arrhenius behavior in the transport properties (diffusion coefficient, relaxation times, and shear viscosity) bordered at T x ~1300K. Unlike in many molecular and macromolecular liquids, this crossover phenomenon occurs in the equilibrium liquid state well above the melting temperature of the system (T m ~ 900K),more » and the crossover temperature is roughly twice of the glass-transition temperature (T g). Below T x, we found the elemental dynamics decoupled and the Stokes-Einstein relation broke down, indicating the onset of heterogeneous spatially correlated dynamics in the system mediated by dynamic communications among local configurational excitations. To directly characterize and visualize the correlated dynamics, we employed a non-parametric, unsupervised machine learning technique and identified dynamical clusters of atoms with similar atomic mobility. The revealed average dynamical cluster size shows an accelerated increase below T x and mimics the trend observed in other ensemble averaged quantities that are commonly used to quantify the spatially heterogeneous dynamics such as the non-Gaussian parameter and the four-point correlation function.« less

  3. The Impact of Exceeding TANF Time Limits on the Access to Healthcare of Low-Income Mothers.

    PubMed

    Narain, Kimberly; Ettner, Susan

    2017-01-01

    The objective of this article is to estimate the relationship of exceeding Temporary Assistance for Needy Families (TANF) time limits, with health insurance, healthcare, and health outcomes. The authors use Heckman selection models that exploit variability in state time-limit duration and timing of policy implementation as identifying exclusion restrictions to adjust the effect estimates of exceeding time limits for possible correlations between the probability of exceeding time limits and unobservable factors influencing the outcomes. The authors find that exceeding time limits decreases the predicted probability of Medicaid coverage, increases the predicted probability of being uninsured, and decreases the predicted probability of annual medical provider contact.

  4. Statistical analysis on multifractal detrended cross-correlation coefficient for return interval by oriented percolation

    NASA Astrophysics Data System (ADS)

    Deng, Wei; Wang, Jun

    2015-06-01

    We investigate and quantify the multifractal detrended cross-correlation of return interval series for Chinese stock markets and a proposed price model, the price model is established by oriented percolation. The return interval describes the waiting time between two successive price volatilities which are above some threshold, the present work is an attempt to quantify the level of multifractal detrended cross-correlation for the return intervals. Further, the concept of MF-DCCA coefficient of return intervals is introduced, and the corresponding empirical research is performed. The empirical results show that the return intervals of SSE and SZSE are weakly positive multifractal power-law cross-correlated, and exhibit the fluctuation patterns of MF-DCCA coefficients. The similar behaviors of return intervals for the price model is also demonstrated.

  5. Probabilistic assessment of precipitation-triggered landslides using historical records of landslide occurence, Seattle, Washington

    USGS Publications Warehouse

    Coe, J.A.; Michael, J.A.; Crovelli, R.A.; Savage, W.Z.; Laprade, W.T.; Nashem, W.D.

    2004-01-01

    Ninety years of historical landslide records were used as input to the Poisson and binomial probability models. Results from these models show that, for precipitation-triggered landslides, approximately 9 percent of the area of Seattle has annual exceedance probabilities of 1 percent or greater. Application of the Poisson model for estimating the future occurrence of individual landslides results in a worst-case scenario map, with a maximum annual exceedance probability of 25 percent on a hillslope near Duwamish Head in West Seattle. Application of the binomial model for estimating the future occurrence of a year with one or more landslides results in a map with a maximum annual exceedance probability of 17 percent (also near Duwamish Head). Slope and geology both play a role in localizing the occurrence of landslides in Seattle. A positive correlation exists between slope and mean exceedance probability, with probability tending to increase as slope increases. Sixty-four percent of all historical landslide locations are within 150 m (500 ft, horizontal distance) of the Esperance Sand/Lawton Clay contact, but within this zone, no positive or negative correlation exists between exceedance probability and distance to the contact.

  6. Information-theoretic indices usage for the prediction and calculation of octanol-water partition coefficient.

    PubMed

    Persona, Marek; Kutarov, Vladimir V; Kats, Boris M; Persona, Andrzej; Marczewska, Barbara

    2007-01-01

    The paper describes the new prediction method of octanol-water partition coefficient, which is based on molecular graph theory. The results obtained using the new method are well correlated with experimental values. These results were compared with the ones obtained by use of ten other structure correlated methods. The comparison shows that graph theory can be very useful in structure correlation research.

  7. Analytic posteriors for Pearson's correlation coefficient.

    PubMed

    Ly, Alexander; Marsman, Maarten; Wagenmakers, Eric-Jan

    2018-02-01

    Pearson's correlation is one of the most common measures of linear dependence. Recently, Bernardo (11th International Workshop on Objective Bayes Methodology, 2015) introduced a flexible class of priors to study this measure in a Bayesian setting. For this large class of priors, we show that the (marginal) posterior for Pearson's correlation coefficient and all of the posterior moments are analytic. Our results are available in the open-source software package JASP.

  8. Validity of a self-administered food frequency questionnaire in the 5-year follow-up survey of the JPHC Study Cohort I to assess sodium and potassium intake: comparison with dietary records and 24-hour urinary excretion level.

    PubMed

    Sasaki, Satoshi; Ishihara, Junko; Tsugane, Shoichiro

    2003-01-01

    We compared the intake levels of sodium and potassium assessed with a self-administered semi-quantitative food frequency questionnaire (FFQ) used in a 5-year follow-up survey of the JPHC study and 28-day dietary record (DR), and the corresponding two 24-hour urinary excretion levels (32 men and 57 women) in 3-areas, i.e., Ninohe, Yokote, and Saku Public Health Center areas. The Spearman rank correlation coefficients between dietary sodium assessed with FFQ and the urinary excretion for crude values were 0.24 and -0.10 in men and women, respectively. After adjusting for energy and creatinine, the sodium correlation coefficients were 0.35 and 0.25 in men and women, respectively. The correlation coefficients for crude potassium values were 0.18 and -0.13 in men and women, respectively. After adjusting for energy and creatinine, the potassium correlation coefficients were 0.48 and 0.18 in men and women, respectively in conclusion, a weak correlation was observed both for sodium and potassium after energy and creatinine adjustment in men, whereas no meaningful correlation was observed in women.

  9. 28 CFR 50.14 - Guidelines on employee selection procedures.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... out are: Assumptions of validity based on a procedure's name or descriptive labels; all forms of... relationship (e.g., correlation coefficient) between performance on a selection procedure and one or more... upon a study involving a large number of subjects and has a low correlation coefficient will be subject...

  10. 28 CFR 50.14 - Guidelines on employee selection procedures.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... out are: Assumptions of validity based on a procedure's name or descriptive labels; all forms of... relationship (e.g., correlation coefficient) between performance on a selection procedure and one or more... upon a study involving a large number of subjects and has a low correlation coefficient will be subject...

  11. 28 CFR 50.14 - Guidelines on employee selection procedures.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... out are: Assumptions of validity based on a procedure's name or descriptive labels; all forms of... relationship (e.g., correlation coefficient) between performance on a selection procedure and one or more... upon a study involving a large number of subjects and has a low correlation coefficient will be subject...

  12. 28 CFR 50.14 - Guidelines on employee selection procedures.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... out are: Assumptions of validity based on a procedure's name or descriptive labels; all forms of... relationship (e.g., correlation coefficient) between performance on a selection procedure and one or more... upon a study involving a large number of subjects and has a low correlation coefficient will be subject...

  13. 28 CFR 50.14 - Guidelines on employee selection procedures.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... out are: Assumptions of validity based on a procedure's name or descriptive labels; all forms of... relationship (e.g., correlation coefficient) between performance on a selection procedure and one or more... upon a study involving a large number of subjects and has a low correlation coefficient will be subject...

  14. Inferential Procedures for Correlation Coefficients Corrected for Attenuation.

    ERIC Educational Resources Information Center

    Hakstian, A. Ralph; And Others

    1988-01-01

    A model and computation procedure based on classical test score theory are presented for determination of a correlation coefficient corrected for attenuation due to unreliability. Delta and Monte Carlo method applications are discussed. A power analysis revealed no serious loss in efficiency resulting from correction for attentuation. (TJH)

  15. Meta-Analysis of the Correlation between Apparent Diffusion Coefficient and Standardized Uptake Value in Malignant Disease

    PubMed Central

    Deng, Shengming; Wu, Zhifang; Wu, Yiwei; Zhang, Wei; Li, Jihui; Dai, Na

    2017-01-01

    The objective of this meta-analysis is to explore the correlation between the apparent diffusion coefficient (ADC) on diffusion-weighted MR and the standard uptake value (SUV) of 18F-FDG on PET/CT in patients with cancer. Databases such as PubMed (MEDLINE included), EMBASE, and Cochrane Database of Systematic Review were searched for relevant original articles that explored the correlation between SUV and ADC in English. After applying Fisher's r-to-z transformation, correlation coefficient (r) values were extracted from each study and 95% confidence intervals (CIs) were calculated. Sensitivity and subgroup analyses based on tumor type were performed to investigate the potential heterogeneity. Forty-nine studies were eligible for the meta-analysis, comprising 1927 patients. Pooled r for all studies was −0.35 (95% CI: −0.42–0.28) and exhibited a notable heterogeneity (I2 = 78.4%; P < 0.01). In terms of the cancer type subgroup analysis, combined correlation coefficients of ADC/SUV range from −0.12 (lymphoma, n = 5) to −0.59 (pancreatic cancer, n = 2). We concluded that there is an average negative correlation between ADC and SUV in patients with cancer. Higher correlations were found in the brain tumor, cervix carcinoma, and pancreas cancer. However, a larger, prospective study is warranted to validate these findings in different cancer types. PMID:29097924

  16. Meta-Analysis of the Correlation between Apparent Diffusion Coefficient and Standardized Uptake Value in Malignant Disease.

    PubMed

    Deng, Shengming; Wu, Zhifang; Wu, Yiwei; Zhang, Wei; Li, Jihui; Dai, Na; Zhang, Bin; Yan, Jianhua

    2017-01-01

    The objective of this meta-analysis is to explore the correlation between the apparent diffusion coefficient (ADC) on diffusion-weighted MR and the standard uptake value (SUV) of 18 F-FDG on PET/CT in patients with cancer. Databases such as PubMed (MEDLINE included), EMBASE, and Cochrane Database of Systematic Review were searched for relevant original articles that explored the correlation between SUV and ADC in English. After applying Fisher's r -to- z transformation, correlation coefficient ( r ) values were extracted from each study and 95% confidence intervals (CIs) were calculated. Sensitivity and subgroup analyses based on tumor type were performed to investigate the potential heterogeneity. Forty-nine studies were eligible for the meta-analysis, comprising 1927 patients. Pooled r for all studies was -0.35 (95% CI: -0.42-0.28) and exhibited a notable heterogeneity ( I 2 = 78.4%; P < 0.01). In terms of the cancer type subgroup analysis, combined correlation coefficients of ADC/SUV range from -0.12 (lymphoma, n = 5) to -0.59 (pancreatic cancer, n = 2). We concluded that there is an average negative correlation between ADC and SUV in patients with cancer. Higher correlations were found in the brain tumor, cervix carcinoma, and pancreas cancer. However, a larger, prospective study is warranted to validate these findings in different cancer types.

  17. LASER APPLICATIONS AND OTHER TOPICS IN QUANTUM ELECTRONICS: On the aerosol backscattering coefficient in atmosphere in the spectral range 9-13.5μm

    NASA Astrophysics Data System (ADS)

    Vasil'ev, B. I.; Mannoun, Oussama

    2007-05-01

    The aerosol backscattering coefficient βπ in a surface atmospheric layer is calculated at the emission lines of NH3 and CO2 lasers (9-13.5 μm). It is shown that the coefficients βπ at the emission lines of an NH3 laser (11-13.5 μm) are comparable with the coefficients βπ at the emission lines of a CO2 laser near 10.6 μm. The dependence of βπ on the humidity and type of aerosols is studied. It is also shown that the coefficient βπ in a surface atmospheric layer at the lasing of an NH3 laser varies from 10-10 to 7×10-9 cm-1 sr-1. The lidar aerosol ratio is calculated as a function of the mean aerosol radius. It is found that this ratio is independent of the particle size for aerosol particles of radius exceeding 40 μm for the 11.7-μm aP(4,0) line of the ammonia laser.

  18. Occurrence and hydrogeochemistry of radiochemical constituents in groundwater of Jefferson County and surrounding areas, southwestern Montana, 2007 through 2010

    USGS Publications Warehouse

    Caldwell, Rodney R.; Nimick, David A.; DeVaney, Rainie M.

    2014-01-01

    The U.S. Geological Survey, in cooperation with Jefferson County and the Jefferson Valley Conservation District, sampled groundwater in southwestern Montana to evaluate the occurrence and concentration of naturally-occurring radioactive constituents and to identify geologic settings and environmental conditions in which elevated concentrations occur. A total of 168 samples were collected from 128 wells within Broadwater, Deer Lodge, Jefferson, Lewis and Clark, Madison, Powell, and Silver Bow Counties from 2007 through 2010. Most wells were used for domestic purposes and were primary sources of drinking water for individual households. Water-quality samples were collected from wells completed within six generalized geologic units, and analyzed for constituents including uranium, radon, gross alpha-particle activity, and gross beta-particle activity. Thirty-eight wells with elevated concentrations or activities were sampled a second time to examine variability in water quality throughout time. These water-quality samples were analyzed for an expanded list of radioactive constituents including the following: three isotopes of uranium (uranium-234, uranium-235, and uranium-238), three isotopes of radium (radium-224, radium-226, and radium-228), and polonium-210. Existing U.S. Geological Survey and Montana Bureau of Mines and Geology uranium and radon water-quality data collected as part of other investigations through 2011 from wells within the study area were compiled as part of this investigation. Water-quality data from this study were compared to data collected nationwide by the U.S. Geological Survey through 2011. Radionuclide samples for this study typically were analyzed within a few days after collection, and therefore data for this study may closely represent the concentrations and activities of water being consumed locally from domestic wells. Radioactive constituents were detected in water from every well sampled during this study regardless of location or geologic unit. Nearly 41 percent of sampled wells had at least one radioactive constituent concentration that exceeded U.S. Environmental Protection Agency drinking-water standards or screening levels. Uranium concentrations were higher than the U.S. Environmental Protection Agency maximum contaminant level (MCL) of 30 micrograms per liter in samples from 14 percent of the wells. Radon concentrations exceeded a proposed MCL of 4,000 picocuries per liter in 27 percent of the wells. Combined radium (radium-226 and radium-228) exceeded the MCL of 5 picocuries per liter in samples from 10 of 47 wells. About 40 percent (42 of 104 wells) of the wells had gross alpha-particle activities (72-hour count) at or greater than a screening level of 15 pCi/L. Gross beta-particle activity exceeded the U.S. Environmental Protection Agency 50 picocuries per liter screening level in samples from 5 of 104 wells. Maximum radium-224 and polonium-210 activities in study wells were 16.1 and 3.08 picocuries per liter, respectively; these isotopes are constituents of human-health concern, but the U.S. Environmental Protection Agency has not established MCLs for them. Radioactive constituent concentrations or activities exceeded at least one established drinking-water standard, proposed drinking-water standard, or screening level in groundwater samples from five of six generalized geologic units assessed during this study. Radioactive constituent concentrations or activities were variable not only within each geologic unit, but also among wells that were completed in the same geologic unit and in close proximity to one another. Established or proposed drinking-water standards were exceeded most frequently in water from wells completed in the generalized geologic unit that includes rocks of the Boulder batholith and other Tertiary through Cretaceous igneous intrusive rocks (commonly described as granite). Specifically, of the wells completed in the Boulder batholith and related rocks sampled as part of this study, 24 percent exceeded the MCL of 30 micrograms per liter for uranium, 50 percent exceeded the proposed alternative MCL of 4,000 picocuries per liter for radon, and 27 percent exceeded the MCL of 5 micrograms per liter for combined radium-226 and radium-228. Elevated radioactive constituent values were detected in samples representing a large range of field properties and water types. Correlations between radioactive constituents and pH, dissolved oxygen, and most major ions were not statistically significant (p-value > 0.05) or were weakly correlated with Spearman correlation coefficients (rho) ranging from -0.5 to 0.5. Moderate correlations did exist between gross beta-particle activity and potassium (rho = 0.72 to 0.82), likely because one potassium isotope (potassium-40) is a beta-particle emitter. Total dissolved solids and specific conductance also were moderately correlated (rho = 0.62 to 0.71) with gross alpha-particle and gross beta-particle activity, indicating that higher radioactivity values can be associated with higher total dissolved solids. Correlations were evaluated among radioactive constituents. Moderate to strong correlations occurred between gross alpha-particle and beta-particle activities (rho = 0.77 to 0.96) and radium isotopes (rho = 0.78 to 0.92). Correlations between gross alpha-particle activity (72-hour count) and all analyzed radioactive constituents were statistically significant (p-value Radiochemical results varied temporally in samples from several of the thirty-eight wells sampled at least twice during the study. The time between successive sampling events ranged from about 1 to 10 months for 29 wells to about 3 years for the other 9 wells. Radiochemical constituents that varied by greater than 30 percent between sampling events included uranium (29 percent of the resampled wells), and radon (11 percent of the resampled wells), gross alpha-particle activity (38 percent of the resampled wells), and gross beta-particle activity (15 percent of the resampled wells). Variability in uranium concentrations from two wells was sufficiently large that concentrations were less than the MCL in the first set of samples and greater than the MCL in the second. Sample holding times affect analytical results in this study. Gross alpha-particle and gross beta-particle activities were measured twice, 72 hours and 30 days after sample collection. Gross alpha-particle activity decreased an average of 37 percent between measurements, indicating the presence of short-lived alpha-emitting radionuclides in these samples. Gross beta-particle activity increased an average of 31 percent between measurements, indicating ingrowth of longer-lived beta-emitting radionuclides.

  19. Development of a rapid, simple assay of plasma total carotenoids

    PubMed Central

    2012-01-01

    Background Plasma total carotenoids can be used as an indicator of risk of chronic disease. Laboratory analysis of individual carotenoids by high performance liquid chromatography (HPLC) is time consuming, expensive, and not amenable to use beyond a research laboratory. The aim of this research is to establish a rapid, simple, and inexpensive spectrophotometric assay of plasma total carotenoids that has a very strong correlation with HPLC carotenoid profile analysis. Results Plasma total carotenoids from 29 volunteers ranged in concentration from 1.2 to 7.4 μM, as analyzed by HPLC. A linear correlation was found between the absorbance at 448 nm of an alcohol / heptane extract of the plasma and plasma total carotenoids analyzed by HPLC, with a Pearson correlation coefficient of 0.989. The average coefficient of variation for the spectrophotometric assay was 6.5% for the plasma samples. The limit of detection was about 0.3 μM and was linear up to about 34 μM without dilution. Correlations between the integrals of the absorption spectra in the range of carotenoid absorption and total plasma carotenoid concentration gave similar results to the absorbance correlation. Spectrophotometric assay results also agreed with the calculated expected absorbance based on published extinction coefficients for the individual carotenoids, with a Pearson correlation coefficient of 0.988. Conclusion The spectrophotometric assay of total carotenoids strongly correlated with HPLC analysis of carotenoids of the same plasma samples and expected absorbance values based on extinction coefficients. This rapid, simple, inexpensive assay, when coupled with the carotenoid health index, may be useful for nutrition intervention studies, population cohort studies, and public health interventions. PMID:23006902

  20. [Tobacco quality analysis of industrial classification of different years using near-infrared (NIR) spectrum].

    PubMed

    Wang, Yi; Xiang, Ma; Wen, Ya-Dong; Yu, Chun-Xia; Wang, Luo-Ping; Zhao, Long-Lian; Li, Jun-Hui

    2012-11-01

    In this study, tobacco quality analysis of main Industrial classification of different years was carried out applying spectrum projection and correlation methods. The group of data was near-infrared (NIR) spectrum from Hongta Tobacco (Group) Co., Ltd. 5730 tobacco leaf Industrial classification samples from Yuxi in Yunnan province from 2007 to 2010 year were collected using near infrared spectroscopy, which from different parts and colors and all belong to tobacco varieties of HONGDA. The conclusion showed that, when the samples were divided to two part by the ratio of 2:1 randomly as analysis and verification sets in the same year, the verification set corresponded with the analysis set applying spectrum projection because their correlation coefficients were above 0.98. The correlation coefficients between two different years applying spectrum projection were above 0.97. The highest correlation coefficient was the one between 2008 and 2009 year and the lowest correlation coefficient was the one between 2007 and 2010 year. At the same time, The study discussed a method to get the quantitative similarity values of different industrial classification samples. The similarity and consistency values were instructive in combination and replacement of tobacco leaf blending.

  1. Increased correlation coefficient between the written test score and tutors' performance test scores after training of tutors for assessment of medical students during problem-based learning course in Malaysia.

    PubMed

    Jaiprakash, Heethal; Min, Aung Ko Ko; Ghosh, Sarmishtha

    2016-03-01

    This paper is aimed at finding if there was a change of correlation between the written test score and tutors' performance test scores in the assessment of medical students during a problem-based learning (PBL) course in Malaysia. This is a cross-sectional observational study, conducted among 264 medical students in two groups from November 2010 to November 2012. The first group's tutors did not receive tutor training; while the second group's tutors were trained in the PBL process. Each group was divided into high, middle and low achievers based on their end-of-semester exam scores. PBL scores were taken which included written test scores and tutors' performance test scores. Pearson correlation coefficient was calculated between the two kinds of scores in each group. The correlation coefficient between the written scores and tutors' scores in group 1 was 0.099 (p<0.001) and for group 2 was 0.305 (p<0.001). The higher correlation coefficient in the group where tutors received the PBL training reinforces the importance of tutor training before their participation in the PBL course.

  2. p-capture reaction cycles in rotating massive stars and their impact on elemental abundances in globular cluster stars: A case study of O, Na and Al

    NASA Astrophysics Data System (ADS)

    Mahanta, Upakul; Goswami, Aruna; Duorah, Hiralal; Duorah, Kalpana

    2017-08-01

    Elemental abundance patterns of globular cluster stars can provide important clues for understanding cluster formation and early chemical evolution. The origin of the abundance patterns, however, still remains poorly understood. We have studied the impact of p-capture reaction cycles on the abundances of oxygen, sodium and aluminium considering nuclear reaction cycles of carbon-nitrogen-oxygen-fluorine, neon-sodium and magnesium-aluminium in massive stars in stellar conditions of temperature range 2×107 to 10×107 K and typical density of 102 gm cc-1. We have estimated abundances of oxygen, sodium and aluminium with respect to Fe, which are then assumed to be ejected from those stars because of rotation reaching a critical limit. These ejected abundances of elements are then compared with their counterparts that have been observed in some metal-poor evolved stars, mainly giants and red giants, of globular clusters M3, M4, M13 and NGC 6752. We observe an excellent agreement with [O/Fe] between the estimated and observed abundance values for globular clusters M3 and M4 with a correlation coefficient above 0.9 and a strong linear correlation for the remaining two clusters with a correlation coefficient above 0.7. The estimated [Na/Fe] is found to have a correlation coefficient above 0.7, thus implying a strong correlation for all four globular clusters. As far as [Al/Fe] is concerned, it also shows a strong correlation between the estimated abundance and the observed abundance for globular clusters M13 and NGC 6752, since here also the correlation coefficient is above 0.7 whereas for globular cluster M4 there is a moderate correlation found with a correlation coefficient above 0.6. Possible sources of these discrepancies are discussed.

  3. An Exploratory Analysis of Factors Affecting Participation in Air Force Knowledge Now Communities of Practice

    DTIC Science & Technology

    2004-03-01

    reliability coefficients are presented in chapter four in the factor analysis section. Along with Crobach’s Alpha coefficients, the Kaiser - Meyer - Olkin ...the pattern of correlation coefficients > 0.300 in the correlation matrix • Kaiser - Meyer - Olkin Measure of Sampling Adequacy (MSA) > 0.700 • Bartlett’s...exploratory factor analysis. The Kaiser - Meyer - Olkin measure of sampling adequacy yielded a value of .790, and Bartlett’s test of sphericity yielded a

  4. Fundamental Studies of Droplet Interactions in Dense Sprays

    DTIC Science & Technology

    1992-12-31

    correlations for the drag coefficients, Nusselt numbers, and Sherwood numbers for hydrocarbon fuel droplets in dense sprays were obtained. 14. SUBJECYTEM...tions for the drag coefficients, Nusselt numbers, and Sherwood numbers for hydrocarbon fuel droplets in dense sprays were obtained. Nomenclature a...the drag coefficient, lift coefficient, moment coefficient, Nusselt number, Sherwood number, and vaporization rates are different from those of an

  5. Heat of transport of air in clay.

    PubMed

    Minkin, Leonid; Shapovalov, Alexander S

    2007-01-01

    By measuring the thermomolecular pressure difference and using principles of irreversible thermodynamics, heat of transport of air in clay and its coefficient of diffusion are found. A comparison of thermotranspiration and pressure driven gas fluxes through concrete slab in homes is examined. It is shown that thermotranspiration air/radon flow may greatly exceed diffusion (pressure driven) flow in homes.

  6. Modeling Earth's surface topography: decomposition of the static and dynamic components

    NASA Astrophysics Data System (ADS)

    Guerri, M.; Cammarano, F.; Tackley, P. J.

    2017-12-01

    Isolating the portion of topography supported by mantle convection, the so-called dynamic topography, would give us precious information on vigor and style of the convection itself. Contrasting results on the estimate of dynamic topography motivate us to analyse the sources of uncertainties affecting its modeling. We obtain models of mantle and crust density, leveraging on seismic and mineral physics constraints. We use the models to compute isostatic topography and residual topography maps. Estimates of dynamic topography and associated synthetic geoid are obtained by instantaneous mantle flow modeling. We test various viscosity profiles and 3D viscosity distributions accounting for inferred lateral variations in temperature. We find that the patterns of residual and dynamic topography are robust, with an average correlation coefficient of 0.74 and 0.71, respectively. The amplitudes are however poorly constrained. For the static component, the considered lithospheric mantle density models result in topographies that differ, on average, 720 m, with peaks reaching 1.7 km. The crustal density models produce variations in isostatic topography averaging 350 m, with peaks of 1 km. For the dynamic component, we obtain peak-to-peak topography amplitude exceeding 3 km for all the tested mantle density and viscosity models. Such values of dynamic topography produce geoid undulations that are not in agreement with observations. Assuming chemical heterogeneities in the lower mantle, in correspondence with the LLSVPs (Large Low Shear wave Velocity Provinces), helps to decrease the amplitudes of dynamic topography and geoid, but reduces the correlation between synthetic and observed geoid. The correlation coefficients between the residual and dynamic topography maps is always less than 0.55. In general, our results indicate that, i) current knowledge of crust density, mantle density and mantle viscosity is still limited, ii) it is important to account for all the various sources of uncertainties when computing static and dynamic topography. In conclusion, a multidisciplinary approach, which involves multiple geophysics observations and constraints from mineral physics, is necessary for obtaining robust density models and, consequently, for properly estimating the dynamic topography.

  7. Interspike interval correlation in a stochastic exponential integrate-and-fire model with subthreshold and spike-triggered adaptation.

    PubMed

    Shiau, LieJune; Schwalger, Tilo; Lindner, Benjamin

    2015-06-01

    We study the spike statistics of an adaptive exponential integrate-and-fire neuron stimulated by white Gaussian current noise. We derive analytical approximations for the coefficient of variation and the serial correlation coefficient of the interspike interval assuming that the neuron operates in the mean-driven tonic firing regime and that the stochastic input is weak. Our result for the serial correlation coefficient has the form of a geometric sequence and is confirmed by the comparison to numerical simulations. The theory predicts various patterns of interval correlations (positive or negative at lag one, monotonically decreasing or oscillating) depending on the strength of the spike-triggered and subthreshold components of the adaptation current. In particular, for pure subthreshold adaptation we find strong positive ISI correlations that are usually ascribed to positive correlations in the input current. Our results i) provide an alternative explanation for interspike-interval correlations observed in vivo, ii) may be useful in fitting point neuron models to experimental data, and iii) may be instrumental in exploring the role of adaptation currents for signal detection and signal transmission in single neurons.

  8. Sectoral risk research about input-output structure of the United States

    NASA Astrophysics Data System (ADS)

    Zhang, Mao

    2018-02-01

    There exist rare researches about economic risk in sectoral level, which is significantly important for risk prewarning. This paper employed status coefficient to measure the symmetry of economic subnetwork, which is negatively correlated with sectoral risk. Then, we do empirical research in both cross section and time series dimensions. In cross section dimension, we study the correlation between sectoral status coefficient and sectoral volatility, earning rate and Sharpe ratio respectively in the year 2015. Next, in the perspective of time series, we first investigate the correlation change between sectoral status coefficient and annual total output from 1997 to 2015. Then, we divide the 71 sectors in America into agriculture, manufacturing, services and government, compare the trend terms of average sectoral status coefficients of the four industries and illustrate the causes behind it. We also find obvious abnormality in the sector of housing. At last, this paper puts forward some suggestions for the federal government.

  9. Correlation Between the Field Line and Particle Diffusion Coefficients in the Stochastic Fields of a Tokamak

    NASA Astrophysics Data System (ADS)

    Calvin, Mark; Punjabi, Alkesh

    1996-11-01

    We use the method of quasi-magnetic surfaces to calculate the correlation between the field line and particle diffusion coefficients. The magnetic topology of a tokamak is perturbed by a spectrum of neighboring resonant resistive modes. The Hamiltonian equations of motion for the field line are integrated numerically. Poincare plots of the quasi-magnetic surfaces are generated initially and after the field line has traversed a considerable distance. From the areas of the quasi-magnetic surfaces and the field line distance, we estimate the field line diffusion coefficient. We start plasma particles on the initial quasi-surface, and calculate the particle diffusion coefficient from our Monte Carlo method (Punjabi A., Boozer A., Lam M., Kim H. and Burke K., J. Plasma Phys.), 44, 405 (1990). We then estimate the correlation between the particle and field diffusion as the strength of the resistive modes is varied.

  10. Linking land use with pesticides in Dutch surface waters.

    PubMed

    Van't, Zelfde M T; Tamis, W L M; Vijver, M G; De Snoo, G R

    2012-01-01

    Compared with other European countries The Netherlands has a relatively high level of pesticide consumption, particularly in agriculture. Many of the compounds concerned end up in surface waters. Surface water quality is routinely monitored and numerous pesticides are found to be present in high concentrations, with various standards being regularly exceeded. Many standards-breaching pesticides exhibit regional patterns that can be traced back to land use. These patterns have been statistically analysed by correlating surface area per land use category with standards exceedance per pesticide, thereby identifying numerous significant correlations with respect to breaches of both the ecotoxicological standard (Maximum Tolerable Risk, MTR) and the drinking water standard. In the case of the MTR, greenhouse horticulture, floriculture and bulb-growing have the highest number as well as percentage of standard-breaching pesticides, despite these market segments being relatively small in terms of area cropped. Cereals, onions, vegetables, perennial border plants and pulses are also associated with many pesticides that exceed the drinking water standard. When a correction is made for cropped acreage, cereals and potatoes also prove to be a major contributor to monitoring sites where the MTR standard is exceeded. Over the period 1998-2006 the land-use categories with the most and highest percentage of standards-exceeding pesticides (greenhouse horticulture, bulb-growing and flower cultivation) showed an increase in the percentage of standards-exceeding compounds.

  11. Urdu translation of the Hamilton Rating Scale for Depression: Results of a validation study

    PubMed Central

    Hashmi, Ali M.; Naz, Shahana; Asif, Aftab; Khawaja, Imran S.

    2016-01-01

    Objective: To develop a standardized validated version of the Hamilton Rating Scale for Depression (HAM-D) in Urdu. Methods: After translation of the HAM-D into the Urdu language following standard guidelines, the final Urdu version (HAM-D-U) was administered to 160 depressed outpatients. Inter-item correlation was assessed by calculating Cronbach alpha. Correlation between HAM-D-U scores at baseline and after a 2-week interval was evaluated for test-retest reliability. Moreover, scores of two clinicians on HAM-D-U were compared for inter-rater reliability. For establishing concurrent validity, scores of HAM-D-U and BDI-U were compared by using Spearman correlation coefficient. The study was conducted at Mayo Hospital, Lahore, from May to December 2014. Results: The Cronbach alpha for HAM-D-U was 0.71. Composite scores for HAM-D-U at baseline and after a 2-week interval were also highly correlated with each other (Spearman correlation coefficient 0.83, p-value < 0.01) indicating good test-retest reliability. Composite scores for HAM-D-U and BDI-U were positively correlated with each other (Spearman correlation coefficient 0.85, p < 0.01) indicating good concurrent validity. Scores of two clinicians for HAM-D-U were also positively correlated (Spearman correlation coefficient 0.82, p-value < 0.01) indicated good inter-rater reliability. Conclusion: The HAM-D-U is a valid and reliable instrument for the assessment of Depression. It shows good inter-rater and test-retest reliability. The HAM-D-U can be a tool either for clinical management or research. PMID:28083049

  12. Urdu translation of the Hamilton Rating Scale for Depression: Results of a validation study.

    PubMed

    Hashmi, Ali M; Naz, Shahana; Asif, Aftab; Khawaja, Imran S

    2016-01-01

    To develop a standardized validated version of the Hamilton Rating Scale for Depression (HAM-D) in Urdu. After translation of the HAM-D into the Urdu language following standard guidelines, the final Urdu version (HAM-D-U) was administered to 160 depressed outpatients. Inter-item correlation was assessed by calculating Cronbach alpha. Correlation between HAM-D-U scores at baseline and after a 2-week interval was evaluated for test-retest reliability. Moreover, scores of two clinicians on HAM-D-U were compared for inter-rater reliability. For establishing concurrent validity, scores of HAM-D-U and BDI-U were compared by using Spearman correlation coefficient. The study was conducted at Mayo Hospital, Lahore, from May to December 2014. The Cronbach alpha for HAM-D-U was 0.71. Composite scores for HAM-D-U at baseline and after a 2-week interval were also highly correlated with each other (Spearman correlation coefficient 0.83, p-value < 0.01) indicating good test-retest reliability. Composite scores for HAM-D-U and BDI-U were positively correlated with each other (Spearman correlation coefficient 0.85, p < 0.01) indicating good concurrent validity. Scores of two clinicians for HAM-D-U were also positively correlated (Spearman correlation coefficient 0.82, p-value < 0.01) indicated good inter-rater reliability. The HAM-D-U is a valid and reliable instrument for the assessment of Depression. It shows good inter-rater and test-retest reliability. The HAM-D-U can be a tool either for clinical management or research.

  13. Equity trees and graphs via information theory

    NASA Astrophysics Data System (ADS)

    Harré, M.; Bossomaier, T.

    2010-01-01

    We investigate the similarities and differences between two measures of the relationship between equities traded in financial markets. Our measures are the correlation coefficients and the mutual information. In the context of financial markets correlation coefficients are well established whereas mutual information has not previously been as well studied despite its theoretically appealing properties. We show that asset trees which are derived from either the correlation coefficients or the mutual information have a mixture of both similarities and differences at the individual equity level and at the macroscopic level. We then extend our consideration from trees to graphs using the "genus 0" condition recently introduced in order to study the networks of equities.

  14. Experimental determination of turbulence in a GH2-GOX rocket combustion chamber

    NASA Technical Reports Server (NTRS)

    Tou, P.; Russell, R.; Ohara, J.

    1974-01-01

    The intensity of turbulence and the Lagrangian correlation coefficient for a gaseous rocket combustion chamber have been determined from the experimental measurements of the tracer gas diffusion. A combination of Taylor's turbulent diffusion theory and Spalding's numerical method for solving the conservation equations of fluid mechanics was used to calculate these quantities. Taylor's theory was extended to consider the inhomogeneity of the turbulence field in the axial direction of the combustion chamber. An exponential function was used to represent the Lagrangian correlation coefficient. The results indicate that the maximum value of the intensity of turbulence is about 15% and the Lagrangian correlation coefficient drops to about 0.12 in one inch of the chamber length.

  15. Investigation of two-phase heat transfer coefficients of argon-freon cryogenic mixed refrigerants

    NASA Astrophysics Data System (ADS)

    Baek, Seungwhan; Lee, Cheonkyu; Jeong, Sangkwon

    2014-11-01

    Mixed refrigerant Joule Thomson refrigerators are widely used in various kinds of cryogenic systems these days. Although heat transfer coefficient estimation for a multi-phase and multi-component fluid in the cryogenic temperature range is necessarily required in the heat exchanger design of mixed refrigerant Joule Thomson refrigerators, it has been rarely discussed so far. In this paper, condensation and evaporation heat transfer coefficients of argon-freon mixed refrigerant are measured in a microchannel heat exchanger. A Printed Circuit Heat Exchanger (PCHE) with 340 μm hydraulic diameter has been developed as a compact microchannel heat exchanger and utilized in the experiment. Several two-phase heat transfer coefficient correlations are examined to discuss the experimental measurement results. The result of this paper shows that cryogenic two-phase mixed refrigerant heat transfer coefficients can be estimated by conventional two-phase heat transfer coefficient correlations.

  16. Commander and User Perceptions of the Army’s Intransit Visibility (ITV) Architecture

    DTIC Science & Technology

    2007-03-01

    covariance matrix; (c) Bartlett’s test of Sphericity; and (d) Kaiser-Meyer- Olkin ( KMO ) measure of sampling adequacy. The inter-item correlation matrix...001), and all diagonal terms had a value of 1 while off-diagonal terms were 0. The KMO measure of sampling adequacy reflects the homogeneity...amongst the variables and serves as an index for comparing the magnitudes of correlation coefficients to partial correlation coefficients. KMO values at

  17. Health Service Quality Scale: Brazilian Portuguese translation, reliability and validity.

    PubMed

    Rocha, Luiz Roberto Martins; Veiga, Daniela Francescato; e Oliveira, Paulo Rocha; Song, Elaine Horibe; Ferreira, Lydia Masako

    2013-01-17

    The Health Service Quality Scale is a multidimensional hierarchical scale that is based on interdisciplinary approach. This instrument was specifically created for measuring health service quality based on marketing and health care concepts. The aim of this study was to translate and culturally adapt the Health Service Quality Scale into Brazilian Portuguese and to assess the validity and reliability of the Brazilian Portuguese version of the instrument. We conducted a cross-sectional, observational study, with public health system patients in a Brazilian university hospital. Validity was assessed using Pearson's correlation coefficient to measure the strength of the association between the Brazilian Portuguese version of the instrument and the SERVQUAL scale. Internal consistency was evaluated using Cronbach's alpha coefficient; the intraclass (ICC) and Pearson's correlation coefficients were used for test-retest reliability. One hundred and sixteen consecutive postoperative patients completed the questionnaire. Pearson's correlation coefficient for validity was 0.20. Cronbach's alpha for the first and second administrations of the final version of the instrument were 0.982 and 0.986, respectively. For test-retest reliability, Pearson's correlation coefficient was 0.89 and ICC was 0.90. The culturally adapted, Brazilian Portuguese version of the Health Service Quality Scale is a valid and reliable instrument to measure health service quality.

  18. Correlation time and diffusion coefficient imaging: application to a granular flow system.

    PubMed

    Caprihan, A; Seymour, J D

    2000-05-01

    A parametric method for spatially resolved measurements for velocity autocorrelation functions, R(u)(tau) = , expressed as a sum of exponentials, is presented. The method is applied to a granular flow system of 2-mm oil-filled spheres rotated in a half-filled horizontal cylinder, which is an Ornstein-Uhlenbeck process with velocity autocorrelation function R(u)(tau) = e(- ||tau ||/tau(c)), where tau(c) is the correlation time and D = tau(c) is the diffusion coefficient. The pulsed-field-gradient NMR method consists of applying three different gradient pulse sequences of varying motion sensitivity to distinguish the range of correlation times present for particle motion. Time-dependent apparent diffusion coefficients are measured for these three sequences and tau(c) and D are then calculated from the apparent diffusion coefficient images. For the cylinder rotation rate of 2.3 rad/s, the axial diffusion coefficient at the top center of the free surface was 5.5 x 10(-6) m(2)/s, the correlation time was 3 ms, and the velocity fluctuation or granular temperature was 1.8 x 10(-3) m(2)/s(2). This method is also applicable to study transport in systems involving turbulence and porous media flows. Copyright 2000 Academic Press.

  19. Measuring monotony in two-dimensional samples

    NASA Astrophysics Data System (ADS)

    Kachapova, Farida; Kachapov, Ilias

    2010-04-01

    This note introduces a monotony coefficient as a new measure of the monotone dependence in a two-dimensional sample. Some properties of this measure are derived. In particular, it is shown that the absolute value of the monotony coefficient for a two-dimensional sample is between |r| and 1, where r is the Pearson's correlation coefficient for the sample; that the monotony coefficient equals 1 for any monotone increasing sample and equals -1 for any monotone decreasing sample. This article contains a few examples demonstrating that the monotony coefficient is a more accurate measure of the degree of monotone dependence for a non-linear relationship than the Pearson's, Spearman's and Kendall's correlation coefficients. The monotony coefficient is a tool that can be applied to samples in order to find dependencies between random variables; it is especially useful in finding couples of dependent variables in a big dataset of many variables. Undergraduate students in mathematics and science would benefit from learning and applying this measure of monotone dependence.

  20. What to Do With "Moderate" Reliability and Validity Coefficients?

    PubMed

    Post, Marcel W

    2016-07-01

    Clinimetric studies may use criteria for test-retest reliability and convergent validity such that correlation coefficients as low as .40 are supportive of reliability and validity. It can be argued that moderate (.40-.60) correlations should not be interpreted in this way and that reliability coefficients <.70 should be considered as indicative of unreliability. Convergent validity coefficients in the .40 to .60 or .40 to .70 range should be considered as indications of validity problems, or as inconclusive at best. Studies on reliability and convergent should be designed in such a way that it is realistic to expect high reliability and validity coefficients. Multitrait multimethod approaches are preferred to study construct (convergent-divergent) validity. Copyright © 2016 American Congress of Rehabilitation Medicine. Published by Elsevier Inc. All rights reserved.

  1. Two-photon absorption in SiO{sub 2}- and (SiO{sub 2} + GeO{sub 2})-based fibres at a wavelength of 349 nm

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Chunaev, D S; Karasik, A Ya

    2014-06-30

    The nonlinear two-photon light absorption coefficients have been measured in an optical fibre with a quartz glass (SiO{sub 2}) core and in a fibre with a germanosilicate glass (SiO{sub 2} + GeO{sub 2}) core. The two-photon absorption coefficient β measured at a wavelength of 349 nm in the (SiO{sub 2} + GeO{sub 2})-based fibre (13.7 cm TW{sup -1}) multiply exceeds that for the pure quartz glass optical fibre (0.54 cm TW{sup -1}). (nonlinear optical phenomena)

  2. Anomalous diffusion of poly(ethylene oxide) in agarose gels.

    PubMed

    Brenner, Tom; Matsukawa, Shingo

    2016-11-01

    We report on the effect of probe size and diffusion time of poly(ethylene) oxide in agarose gels. Time-dependence of the diffusion coefficient, reflecting anomalous diffusion, was observed for poly(ethylene) oxide chains with hydrodynamic radii exceeding about 20nm at an agarose concentration of 2%. The main conclusion is that the pore distribution includes pores that are only several nm across, in agreement with scattering reports in the literature. Interpretation of the diffusion coefficient dependence on the probe size based on a model of entangled rigid rods yielded a rod length of 72nm. Copyright © 2016. Published by Elsevier B.V.

  3. Effects of urban development in the Puget Lowland, Washington, on interannual streamflow patterns: Consequences for channel form and streambed disturbance

    USGS Publications Warehouse

    Konrad, Christopher P.; Booth, Derek B.; Burges, Stephen J.

    2005-01-01

    Recovery and protection of streams in urban areas depend on a comprehensive understanding of how human activities affect stream ecosystems. The hydrologic effects of urban development and the consequences for stream channel form and streambed stability were examined in 16 streams in the Puget Lowland, Washington, using three streamflow metrics that integrate storm‐scale effects of urban development over annual to decadal timescales: the fraction of time that streamflow exceeds the mean streamflow (TQmean), the coefficient of variation of annual maximum streamflow (CVAMF), and the fraction of time that streamflow exceeds the 0.5‐year flood (T0.5). Urban streams had low interannual variability in annual maximum streamflow and brief duration of frequent high flows, as indicated by significant correlations between road density and both CVAMFand T0.5. The broader distribution of streamflow indicated by TQmean may be affected by urban development, but differences in TQmean between streams are also likely a result of other physiographic factors. The increase in the magnitude of frequent high flows due to urban development but not their cumulative duration has important consequences for channel form and bed stability in gravel bed streams because geomorphic equilibrium depends on moderate duration streamflow (e.g., exceeded 10% of the time). Streams with low values of TQmean and T0.5 are narrower than expected from hydraulic geometry. Dimensionless boundary shear stress (t*) for the 0.5‐year flood was inversely related to T0.5 among the streams, indicating frequent and extensive bed disturbance in streams with low values of T0.5. Although stream channels expand and the size of bed material increases in response to urban streamflow patterns, these adjustments may be insufficient to reestablish the disturbance regime in urban streams because of the differential increase in the magnitude of frequent high flows causing disturbance relative to any changes in longer duration, moderate flows that establish a stable channel.

  4. Confidence Intervals for Squared Semipartial Correlation Coefficients: The Effect of Nonnormality

    ERIC Educational Resources Information Center

    Algina, James; Keselman, H. J.; Penfield, Randall D.

    2010-01-01

    The increase in the squared multiple correlation coefficient ([delta]R[superscript 2]) associated with a variable in a regression equation is a commonly used measure of importance in regression analysis. Algina, Keselman, and Penfield found that intervals based on asymptotic principles were typically very inaccurate, even though the sample size…

  5. Accuracy of Range Restriction Correction with Multiple Imputation in Small and Moderate Samples: A Simulation Study

    ERIC Educational Resources Information Center

    Pfaffel, Andreas; Spiel, Christiane

    2016-01-01

    Approaches to correcting correlation coefficients for range restriction have been developed under the framework of large sample theory. The accuracy of missing data techniques for correcting correlation coefficients for range restriction has thus far only been investigated with relatively large samples. However, researchers and evaluators are…

  6. Interrater Reliability Estimators Commonly Used in Scoring Language Assessments: A Monte Carlo Investigation of Estimator Accuracy

    ERIC Educational Resources Information Center

    Morgan, Grant B.; Zhu, Min; Johnson, Robert L.; Hodge, Kari J.

    2014-01-01

    Common estimators of interrater reliability include Pearson product-moment correlation coefficients, Spearman rank-order correlations, and the generalizability coefficient. The purpose of this study was to examine the accuracy of estimators of interrater reliability when varying the true reliability, number of scale categories, and number of…

  7. Correlation Revelation: The Search for Meaning in Pearson's Coefficient

    ERIC Educational Resources Information Center

    Huhn, Craig

    2016-01-01

    When the author was first charged with getting a group of students to understand the correlation coefficient, he did not anticipate the topic would challenge his own understanding, let alone cause him to eventually question the very nature of mathematics itself. On the surface, the idea seemed straightforward, one that millions of students across…

  8. Intraclass Correlation Coefficients in Hierarchical Designs: Evaluation Using Latent Variable Modeling

    ERIC Educational Resources Information Center

    Raykov, Tenko

    2011-01-01

    Interval estimation of intraclass correlation coefficients in hierarchical designs is discussed within a latent variable modeling framework. A method accomplishing this aim is outlined, which is applicable in two-level studies where participants (or generally lower-order units) are clustered within higher-order units. The procedure can also be…

  9. Relationships of the phase velocity with the microarchitectural parameters in bovine trabecular bone in vitro: Application of a stratified model

    NASA Astrophysics Data System (ADS)

    Lee, Kang Il

    2012-08-01

    The present study aims to provide insight into the relationships of the phase velocity with the microarchitectural parameters in bovine trabecular bone in vitro. The frequency-dependent phase velocity was measured in 22 bovine femoral trabecular bone samples by using a pair of transducers with a diameter of 25.4 mm and a center frequency of 0.5 MHz. The phase velocity exhibited positive correlation coefficients of 0.48 and 0.32 with the ratio of bone volume to total volume and the trabecular thickness, respectively, but a negative correlation coefficient of -0.62 with the trabecular separation. The best univariate predictor of the phase velocity was the trabecular separation, yielding an adjusted squared correlation coefficient of 0.36. The multivariate regression models yielded adjusted squared correlation coefficients of 0.21-0.36. The theoretical phase velocity predicted by using a stratified model for wave propagation in periodically stratified media consisting of alternating parallel solid-fluid layers showed reasonable agreements with the experimental measurements.

  10. Clinical correlates of sex hormones in women: The study of health in Pomerania.

    PubMed

    Kische, Hanna; Gross, Stefan; Wallaschofski, Henri; Völzke, Henry; Dörr, Marcus; Nauck, Matthias; Haring, Robin

    2016-09-01

    Despite associations of sex hormones in women with increased cardiometabolic risk and mortality, the clinical correlates of altered sex hormone concentrations in women are less clearly understood. We investigated a broad range of clinical correlates of sex hormones in women from a large population-based sample. Data from 2560 women from two cohorts of the Study of Health in Pomerania were used. Stepwise multivariable regression models were implemented to investigate a broad range of behavioral, socio-demographic, and cardiometabolic clinical correlates related to total testosterone (TT), free testosterone (fT), androstenedione (ASD), dehydroepiandrosterone-sulfate (DHEAS), estrone (E1), estradiol (E2), and sex hormone-binding globulin (SHBG). Waist circumference and BMI (β-coefficient: -0.03; 95% CI: -0.04; 0.03) were inversely related to SHBG, and BMI was positively related to TT (β-coefficient: 0.005; 95% CI: 0.001; 0.009), fT, E1, and E2. Smoking was positively related to TT (β-coefficient: 0.04; 95% CI: 0.01; 0.06), ASD, and fT. Systolic blood pressure (TT: β-coefficient: 0.002; 95% CI: 0.001; 0.003), hypertension (TT: β-coefficient: 0.05; 95% CI: 0.003; 0.11), low-density lipoprotein (LDL) cholesterol (TT: β-coefficient: 0.02; 95% CI: 0.01; 0.05), and total cholesterol (TT: β-coefficient: -0.03; 95% CI: 0.01; 0.05) were positively related to TT and ASD. Finally, type 2 diabetes mellitus (T2DM), and metabolic syndrome (MetS) were positively related to fT, but inversely related to SHBG. Our population-based study, with sex hormone concentrations measured by liquid chromatography tandem mass spectrometry, revealed associations between clinical correlates including waist circumference, smoking, cohabitation, systolic blood pressure, cholesterol, and MetS with sex hormones. Thus, sex hormones and SHBG may play a role in the cardiovascular risk profile of women. Copyright © 2016 Elsevier Inc. All rights reserved.

  11. Multiparametric voxel-based analyses of standardized uptake values and apparent diffusion coefficients of soft-tissue tumours with a positron emission tomography/magnetic resonance system: Preliminary results.

    PubMed

    Sagiyama, Koji; Watanabe, Yuji; Kamei, Ryotaro; Hong, Sungtak; Kawanami, Satoshi; Matsumoto, Yoshihiro; Honda, Hiroshi

    2017-12-01

    To investigate the usefulness of voxel-based analysis of standardized uptake values (SUVs) and apparent diffusion coefficients (ADCs) for evaluating soft-tissue tumour malignancy with a PET/MR system. Thirty-five subjects with either ten low/intermediate-grade tumours or 25 high-grade tumours were prospectively enrolled. Zoomed diffusion-weighted and fluorodeoxyglucose ( 18 FDG)-PET images were acquired along with fat-suppressed T2-weighted images (FST2WIs). Regions of interest (ROIs) were drawn on FST2WIs including the tumour in all slices. ROIs were pasted onto PET and ADC-maps to measure SUVs and ADCs within tumour ROIs. Tumour volume, SUVmax, ADCminimum, the heterogeneity and the correlation coefficients of SUV and ADC were recorded. The parameters of high- and low/intermediate-grade groups were compared, and receiver operating characteristic (ROC) analysis was also performed. The mean correlation coefficient for SUV and ADC in high-grade sarcomas was lower than that of low/intermediate-grade tumours (-0.41 ± 0.25 vs. -0.08 ± 0.34, P < 0.01). Other parameters did not differ significantly. ROC analysis demonstrated that correlation coefficient showed the best diagnostic performance for differentiating the two groups (AUC 0.79, sensitivity 96.0%, specificity 60%, accuracy 85.7%). SUV and ADC determined via PET/MR may be useful for differentiating between high-grade and low/intermediate-grade soft tissue tumours. • PET/MR allows voxel-based comparison of SUVs and ADCs in soft-tissue tumours. • A comprehensive assessment of internal heterogeneity was performed with scatter plots. • SUVmax or ADCminimum could not differentiate high-grade sarcoma from low/intermediate-grade tumours. • Only the correlation coefficient between SUV and ADC differentiated the two groups. • The correlation coefficient showed the best diagnostic performance by ROC analysis.

  12. Characterization of Skin Friction Coefficient, and Relationship to Stratum Corneum Hydration in a Normal Chinese Population

    PubMed Central

    Zhu, Y.H.; Song, S.P.; Luo, W.; Elias, P.M.; Man, M.Q.

    2011-01-01

    Background and Objectives Studies have demonstrated that some cutaneous biophysical properties vary with age, gender and body sites. However, the characteristics of the skin friction coefficient in different genders and age groups have not yet been well established. In the present study, we assess the skin friction coefficient in a larger Chinese population. Methods A total of 633 subjects (300 males and 333 females) aged 0.15–79 years were enrolled. A Frictiometer® FR 770 and Corneometer® CM 825 (C&K MPA 5) were used to measure the skin friction coefficient and stratum corneum hydration, respectively, on the dorsal surface of the hand, the forehead and the canthus. Results In the females, the maximum skin friction coefficients on both the canthus and the dorsal hand skin were observed around the age of 40 years. In the males, the skin friction coefficient on the dorsal hand skin gradually increased from 0 to 40 years of age, and changed little afterward. Skin friction coefficients on some body sites were higher in females than in age-matched males in some age groups. On the canthus and the dorsal hand skin of females, a positive correlation was found between skin friction coefficient and stratum corneum hydration (p < 0.001 and p < 0.0001, respectively). In contrast, in males, the skin friction coefficient was positively correlated with stratum corneum hydration on the forehead and the dorsal hand skin (p < 0.05 and p < 0.0001, respectively). Conclusion The skin friction coefficient varies with age, gender and body site, and positively correlates with stratum corneum hydration on some body sites. PMID:21088455

  13. Characterization of skin friction coefficient, and relationship to stratum corneum hydration in a normal Chinese population.

    PubMed

    Zhu, Y H; Song, S P; Luo, W; Elias, P M; Man, M Q

    2011-01-01

    Studies have demonstrated that some cutaneous biophysical properties vary with age, gender and body sites. However, the characteristics of the skin friction coefficient in different genders and age groups have not yet been well established. In the present study, we assess the skin friction coefficient in a larger Chinese population. A total of 633 subjects (300 males and 333 females) aged 0.15-79 years were enrolled. A Frictiometer FR 770 and Corneometer CM 825 (C&K MPA 5) were used to measure the skin friction coefficient and stratum corneum hydration, respectively, on the dorsal surface of the hand, the forehead and the canthus. In the females, the maximum skin friction coefficients on both the canthus and the dorsal hand skin were observed around the age of 40 years. In the males, the skin friction coefficient on the dorsal hand skin gradually increased from 0 to 40 years of age, and changed little afterward. Skin friction coefficients on some body sites were higher in females than in age-matched males in some age groups. On the canthus and the dorsal hand skin of females, a positive correlation was found between skin friction coefficient and stratum corneum hydration (p < 0.001 and p < 0.0001, respectively). In contrast, in males, the skin friction coefficient was positively correlated with stratum corneum hydration on the forehead and the dorsal hand skin (p < 0.05 and p < 0.0001, respectively). The skin friction coefficient varies with age, gender and body site, and positively correlates with stratum corneum hydration on some body sites. Copyright © 2010 S. Karger AG, Basel.

  14. The Pittsburgh Sleep Quality Index: validation of the Urdu translation.

    PubMed

    Hashmi, Ali Madeeh; Khawaja, Imran Shuja; Butt, Zeeshan; Umair, Muhammad; Naqvi, Suhaib Haider; Jawad-Ul-Haq

    2014-02-01

    To translate and validate the Pittsburgh Sleep Quality Index (PSQI), a standardized self-administered questionnaire for the assessment of subjective sleep quality into the Urdu language. Validation study. Mayo Hospital, Lahore, from March to April 2012. The PSQI was translated into Urdu following standard guidelines. The final Urdu version (PSQI-U) was administered to 200 healthy volunteers comprising medical students, nursing staff and doctors. Inter-item correlation was assessed by calculating Cronbach alpha. Correlation of component scores with global score was assessed by calculating Spearman correlation coefficient. Correlation between global PSQI-U scores at baseline with global scores for each PSQI-U and PSQI-E at 4-week interval was evaluated by calculating Spearman correlation coefficient. Moreover, scores on individual items of the scale at baseline were compared with respective scores after 4-week by t-test. One hundred and eighty five (185) participants completed the PSQI-U at baseline. The Cronbach alpha for PSQI-U was 0.56. Scores on individual components of the PSQI-U and composite scores were all highly correlated with each other (all p-values < 0.01). Composite scores for PSQI-U at baseline and PSQI-E at 4-week interval were also highly correlated with each other (Spearman correlation coefficient 0.74, p-value < 0.01) indicating good linguistic interchangeability. Composite scores for PSQI-U at baseline and at 4-week interval were positively correlated with each other (Spearman correlation coefficient 0.70, p < 0.01) indicating good test-retest reliability. The PSQI-U is a valid and reliable instrument for the assessment of sleep quality. It shows good linguistic interchangeability and test-retest reliability in comparison to the original English version when applied to individuals who speak the Urdu language. The PSQI-U can be a tool either for clinical management or research.

  15. Correlation of serum liver fibrosis markers with severity of liver dysfunction in liver cirrhosis: a retrospective cross-sectional study

    PubMed Central

    Zhu, Cuihong; Qi, Xingshun; Li, Hongyu; Peng, Ying; Dai, Junna; Chen, Jiang; Xia, Chunlian; Hou, Yue; Zhang, Wenwen; Guo, Xiaozhong

    2015-01-01

    Hyaluronic acid (HA), laminin (LN), amino-terminal pro-peptide of type III pro-collagen (PIIINP), and collagen IV (CIV) are four major serum markers of liver fibrosis. This retrospective cross-sectional study aimed to evaluate the correlations of the four serum markers with the severity of liver dysfunction in cirrhotic patients. Between January 2013 and June 2014, a total of 228 patients with a clinical diagnosis with liver cirrhosis and without malignancy underwent the tests of HA, LN, PIIINP, and CIV levels. Laboratory data were collected. Child-Pugh and model for the end-stage of liver diseases (MELD) scores were calculated. Of them, 32%, 40%, and 18% had Child-Pugh class A, B, and C, respectively. MELD score was 7.58±0.50. HA (coefficient r: 0.1612, P=0.0203), LN (coefficient r: 0.2445, P=0.0004), and CIV (coefficient r: 0.2361, P=0.0006) levels significantly correlated with Child-Pugh score, but not PIIINP level. Additionally, LN (coefficient r: 0.2588, P=0.0002) and CIV (coefficient r: 0.1795, P=0.0108) levels significantly correlated with MELD score, but not HA or PIIINP level. In conclusions, HA, LN, and CIV levels might be positively associated with the severity of liver dysfunction in cirrhotic patients. However, given a relatively weak correlation between them, our findings should be cautiously interpreted and further validated. PMID:26131195

  16. The inter and intra rater reliability of the Netball Movement Screening Tool.

    PubMed

    Reid, Duncan A; Vanweerd, Rebecca J; Larmer, Peter J; Kingstone, Rachel

    2015-05-01

    To establish the inter- and intra-rater reliability of the Netball Movement Screening Tool, for screening adolescent female netball players. Inter- and intra-rater reliability study. Forty secondary school netball players were recruited to take part in the study. Twenty subjects were screened simultaneously and independently by two raters to ascertain inter-rater agreement. Twenty subjects were scored by rater one on two occasions, separated by a week, to ascertain intra-rater agreement. Inter and intra-rater agreement was assessed utilising the two-way mixed inter class correlation coefficient and weighted kappa statistics. No significant demographic differences were found between the inter and intra-rater groups of subjects. Inter class correlation coefficients' demonstrated excellent inter-rater (two-way mixed inter class correlation coefficients 0.84, standard error of measurement 0.25) and intra-rater (two-way mixed inter class correlation coefficients 0.96, standard error of measurement 0.13) reliability for the overall Netball Movement Screening Tool score and substantial-excellent (two-way mixed inter class correlation coefficients 1.0-0.65) inter-rater and substantial-excellent intra-rater (two-way mixed inter class correlation coefficients 0.96-0.79) reliability for the component scores of the Netball Movement Screening Tool. Kappa statistic showed substantial to poor inter-rater (k=0.75-0.32) and intra-rater (k=0.77-0.27) agreement for individual tests of the NMST. The Netball Movement Screening Tool may be a reliable screening tool for adolescent netball players; however the individual test scores have low reliability. The screening tool can be administered reliably by raters with similar levels of training in the tool but variable clinical experience. On-going research needs to be undertaken to ascertain whether the Netball Movement Screening Tool is a valid tool in ascertaining increased injury risk for netball players. Copyright © 2014 Sports Medicine Australia. Published by Elsevier Ltd. All rights reserved.

  17. Improved identification of the solution space of aerosol microphysical properties derived from the inversion of profiles of lidar optical data, part 1: theory.

    PubMed

    Kolgotin, Alexei; Müller, Detlef; Chemyakin, Eduard; Romanov, Anton

    2016-12-01

    Multiwavelength Raman/high spectral resolution lidars that measure backscatter coefficients at 355, 532, and 1064 nm and extinction coefficients at 355 and 532 nm can be used for the retrieval of particle microphysical parameters, such as effective and mean radius, number, surface-area and volume concentrations, and complex refractive index, from inversion algorithms. In this study, we carry out a correlation analysis in order to investigate the degree of dependence that may exist between the optical data taken with lidar and the underlying microphysical parameters. We also investigate if the correlation properties identified in our study can be used as a priori or a posteriori constraints for our inversion scheme so that the inversion results can be improved. We made the simplifying assumption of error-free optical data in order to find out what correlations exist in the best case situation. Clearly, for practical applications, erroneous data need to be considered too. On the basis of simulations with synthetic optical data, we find the following results, which hold true for arbitrary particle size distributions, i.e., regardless of the modality or the shape of the size distribution function: surface-area concentrations and extinction coefficients are linearly correlated with a correlation coefficient above 0.99. We also find a correlation coefficient above 0.99 for the extinction coefficient versus (1) the ratio of the volume concentration to effective radius and (2) the product of the number concentration times the sum of the squares of the mean radius and standard deviation of the investigated particle size distributions. Besides that, we find that for particles of any mode fraction of the particle size distribution, the complex refractive index is uniquely defined by extinction- and backscatter-related Ångström exponents, lidar ratios at two wavelengths, and an effective radius.

  18. Real external predictivity of QSAR models: how to evaluate it? Comparison of different validation criteria and proposal of using the concordance correlation coefficient.

    PubMed

    Chirico, Nicola; Gramatica, Paola

    2011-09-26

    The main utility of QSAR models is their ability to predict activities/properties for new chemicals, and this external prediction ability is evaluated by means of various validation criteria. As a measure for such evaluation the OECD guidelines have proposed the predictive squared correlation coefficient Q(2)(F1) (Shi et al.). However, other validation criteria have been proposed by other authors: the Golbraikh-Tropsha method, r(2)(m) (Roy), Q(2)(F2) (Schüürmann et al.), Q(2)(F3) (Consonni et al.). In QSAR studies these measures are usually in accordance, though this is not always the case, thus doubts can arise when contradictory results are obtained. It is likely that none of the aforementioned criteria is the best in every situation, so a comparative study using simulated data sets is proposed here, using threshold values suggested by the proponents or those widely used in QSAR modeling. In addition, a different and simple external validation measure, the concordance correlation coefficient (CCC), is proposed and compared with other criteria. Huge data sets were used to study the general behavior of validation measures, and the concordance correlation coefficient was shown to be the most restrictive. On using simulated data sets of a more realistic size, it was found that CCC was broadly in agreement, about 96% of the time, with other validation measures in accepting models as predictive, and in almost all the examples it was the most precautionary. The proposed concordance correlation coefficient also works well on real data sets, where it seems to be more stable, and helps in making decisions when the validation measures are in conflict. Since it is conceptually simple, and given its stability and restrictiveness, we propose the concordance correlation coefficient as a complementary, or alternative, more prudent measure of a QSAR model to be externally predictive.

  19. Thermal expansion coefficient determination of polylactic acid using digital image correlation

    NASA Astrophysics Data System (ADS)

    Botean, Adrian-Ioan

    2018-02-01

    This paper aims determining the linear thermal expansion coefficient (CTE) of polylactic acid (PLA) using an optical method for measuring deformations called digital image correlation method (DIC). Because PLA is often used in making many pieces with 3D printing technology, it is opportune to know this coefficient to obtain a higher degree of precision in the construction of parts and to monitor deformations when these parts are subjected to a thermal gradient. Are used two PLA discs with 20 and 40% degree of filling. In parallel with this approach was determined the linear thermal expansion coefficient (CTE) for the copper cylinder on the surface of which are placed the two discs of PLA.

  20. Influence of Social and Behavioural Characteristics of Users on Their Evaluation of Subjective Loudness and Acoustic Comfort in Shopping Malls

    PubMed Central

    Meng, Qi; Kang, Jian

    2013-01-01

    A large-scale subjective survey was conducted in six shopping malls in Harbin City, China, to determine the influence of social and behavioural characteristics of users on their evaluation of subjective loudness and acoustic comfort. The analysis of social characteristics shows that evaluation of subjective loudness is influenced by income and occupation, with correlation coefficients or contingency coefficients of 0.10 to 0.40 (p<0.05 or p<0.01). Meanwhile, evaluation of acoustic comfort evaluation is influenced by income, education level, and occupation, with correlation coefficients or contingency coefficients of 0.10 to 0.60 (p<0.05 or p<0.01). The effect of gender and age on evaluation of subjective loudness and acoustic comfort is statistically insignificant. The effects of occupation are mainly caused by the differences in income and education level, in which the effects of income are greater than that of education level. In terms of behavioural characteristics, evaluation of subjective loudness is influenced by the reason for visit, frequency of visit, and length of stay, with correlation coefficients or contingency coefficients of 0.10 to 0.40 (p<0.05 or p<0.01). Evaluation of acoustic comfort is influenced by the reason for visit to the site, the frequency of visit, length of stay, and also season of visit, with correlation coefficients of 0.10 to 0.30 (p<0.05 or p<0.01). In particular, users who are waiting for someone show lower evaluation of acoustic comfort, whereas users who go to shopping malls more than once a month show higher evaluation of acoustic comfort. On the contrary, the influence of the period of visit and the accompanying persons are found insignificant. PMID:23336003

  1. aCORN: An experiment to measure the electron-antineutrino correlation coefficient in free neutron decay

    DOE PAGES

    Collett, B.; Bateman, F.; Bauder, W. K.; ...

    2017-08-01

    Here, we describe an apparatus used to measure the electron-antineutrino angular correlation coefficient in free neutron decay. This apparatus employs a novel measurement technique in which the angular correlation is converted into a proton time-of-flight asymmetry that is counted directly, avoiding the need for proton spectroscopy. We present details of the method, apparatus, detectors, data acquisition, and data reduction scheme, along with a discussion of the important systematic effects.

  2. aCORN: An experiment to measure the electron-antineutrino correlation coefficient in free neutron decay

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Collett, B.; Bateman, F.; Bauder, W. K.

    Here, we describe an apparatus used to measure the electron-antineutrino angular correlation coefficient in free neutron decay. This apparatus employs a novel measurement technique in which the angular correlation is converted into a proton time-of-flight asymmetry that is counted directly, avoiding the need for proton spectroscopy. We present details of the method, apparatus, detectors, data acquisition, and data reduction scheme, along with a discussion of the important systematic effects.

  3. Postconcussive Symptoms in OEF-OIF Veterans: Factor Structure and Impact of Posttraumatic Stress

    DTIC Science & Technology

    2009-06-03

    correlations between NSI full items are presented in Appendix A. Visual inspection of the correlation matrix, the Kaiser - Meyer - Olkin coefficient of .92, and...Spearman rho correlations between NSI residuals are pre- sented in Appendix B. Again, visual inspection of the correla- tion matrix, the Kaiser - Meyer ... Olkin coefficient of .83, and Bartlett’s test of sphericity (x2 5 1,936.0, p , .01) suggested that the matrix could be factored. Principal-components

  4. aCORN: An experiment to measure the electron-antineutrino correlation coefficient in free neutron decay.

    PubMed

    Collett, B; Bateman, F; Bauder, W K; Byrne, J; Byron, W A; Chen, W; Darius, G; DeAngelis, C; Dewey, M S; Gentile, T R; Hassan, M T; Jones, G L; Komives, A; Laptev, A; Mendenhall, M P; Nico, J S; Noid, G; Park, H; Stephenson, E J; Stern, I; Stockton, K J S; Trull, C; Wietfeldt, F E; Yerozolimsky, B G

    2017-08-01

    We describe an apparatus used to measure the electron-antineutrino angular correlation coefficient in free neutron decay. The apparatus employs a novel measurement technique in which the angular correlation is converted into a proton time-of-flight asymmetry that is counted directly, avoiding the need for proton spectroscopy. Details of the method, apparatus, detectors, data acquisition, and data reduction scheme are presented, along with a discussion of the important systematic effects.

  5. Evaluation of estimation methods for organic carbon normalized sorption coefficients

    USGS Publications Warehouse

    Baker, James R.; Mihelcic, James R.; Luehrs, Dean C.; Hickey, James P.

    1997-01-01

    A critically evaluated set of 94 soil water partition coefficients normalized to soil organic carbon content (Koc) is presented for 11 classes of organic chemicals. This data set is used to develop and evaluate Koc estimation methods using three different descriptors. The three types of descriptors used in predicting Koc were octanol/water partition coefficient (Kow), molecular connectivity (mXt) and linear solvation energy relationships (LSERs). The best results were obtained estimating Koc from Kow, though a slight improvement in the correlation coefficient was obtained by using a two-parameter regression with Kow and the third order difference term from mXt. Molecular connectivity correlations seemed to be best suited for use with specific chemical classes. The LSER provided a better fit than mXt but not as good as the correlation with Koc. The correlation to predict Koc from Kow was developed for 72 chemicals; log Koc = 0.903* log Kow + 0.094. This correlation accounts for 91% of the variability in the data for chemicals with log Kow ranging from 1.7 to 7.0. The expression to determine the 95% confidence interval on the estimated Koc is provided along with an example for two chemicals of different hydrophobicity showing the confidence interval of the retardation factor determined from the estimated Koc. The data showed that Koc is not likely to be applicable for chemicals with log Kow < 1.7. Finally, the Koc correlation developed using Kow as a descriptor was compared with three nonclass-specific correlations and two 'commonly used' class-specific correlations to determine which method(s) are most suitable.

  6. Cultural adaptation and validation of a German version of the Arthritis Impact Measurement Scales (AIMS2).

    PubMed

    Rosemann, T; Szecsenyi, J

    2007-10-01

    To validate a translated and culturally adapted version of the Arthritis Impact Measurement Scale (AIMS) 2 in primary care patients with osteoarthritis (OA) of the hip and knee. The AIMS2 was translated into German and culturally adapted. The questionnaire then was administered to 220 primary care patients with OA of the knee or hip. Two hundred and nine questionnaires were returned and analysed. Test-retest reliability was tested in 50 randomly selected patients, of those 42 completed the questionnaire after 2 weeks for a second time. Item-scale correlations were reasonably good as well as the discriminative power of separate scales. The assessment of internal consistency reliability also revealed satisfactory values; Cronbach's alpha was 0.77 or higher for all scales. The test-retest reliability, estimated in an intraclass correlation coefficient (ICC), exceeded 0.90, except the "social activities" scale (0.87). Since only patients with OA of the lower limb were enrolled, substantial floor effects occurred in the "arm function" (28.2%) and the "hand and finger function" scale (29.2%). The principal factor analysis confirmed the postulated three-factor structure with a physical, physiological and social dimension, explaining 48.5%, 13.9% and 6.8% of the variation, respectively. External validity was assessed by calculating correlations to the Western Ontario and MacMaster (WOMAC) osteoarthritis questionnaire a pain visual analogue scale (VAS) and the Kellgren score as well as to disease duration. Spearman's "R" achieved satisfactory values for the corresponding WOMAC scales and the pain-VAS. Correlations with disease duration as well as with the radiological grading were low. The GERMAN-AIMS2 is a reliable and valid instrument to assess the quality of life (QoL) in primary care patients suffering from OA.

  7. Association of Structural Global Brain Network Properties with Intelligence in Normal Aging

    PubMed Central

    Fischer, Florian U.; Wolf, Dominik; Scheurich, Armin; Fellgiebel, Andreas

    2014-01-01

    Higher general intelligence attenuates age-associated cognitive decline and the risk of dementia. Thus, intelligence has been associated with cognitive reserve or resilience in normal aging. Neurophysiologically, intelligence is considered as a complex capacity that is dependent on a global cognitive network rather than isolated brain areas. An association of structural as well as functional brain network characteristics with intelligence has already been reported in young adults. We investigated the relationship between global structural brain network properties, general intelligence and age in a group of 43 cognitively healthy elderly, age 60–85 years. Individuals were assessed cross-sectionally using Wechsler Adult Intelligence Scale-Revised (WAIS-R) and diffusion-tensor imaging. Structural brain networks were reconstructed individually using deterministic tractography, global network properties (global efficiency, mean shortest path length, and clustering coefficient) were determined by graph theory and correlated to intelligence scores within both age groups. Network properties were significantly correlated to age, whereas no significant correlation to WAIS-R was observed. However, in a subgroup of 15 individuals aged 75 and above, the network properties were significantly correlated to WAIS-R. Our findings suggest that general intelligence and global properties of structural brain networks may not be generally associated in cognitively healthy elderly. However, we provide first evidence of an association between global structural brain network properties and general intelligence in advanced elderly. Intelligence might be affected by age-associated network deterioration only if a certain threshold of structural degeneration is exceeded. Thus, age-associated brain structural changes seem to be partially compensated by the network and the range of this compensation might be a surrogate of cognitive reserve or brain resilience. PMID:24465994

  8. Measurement of blood loss during postpartum haemorrhage.

    PubMed

    Lilley, G; Burkett-St-Laurent, D; Precious, E; Bruynseels, D; Kaye, A; Sanders, J; Alikhan, R; Collins, P W; Hall, J E; Collis, R E

    2015-02-01

    We set out to validate the accuracy of gravimetric quantification of blood loss during simulated major postpartum haemorrhage and to evaluate the technique in a consecutive cohort of women experiencing major postpartum haemorrhage. The study took part in a large UK delivery suite over a one-year period. All women who experienced major postpartum haemorrhage were eligible for inclusion. For the validation exercise, in a simulated postpartum haemorrhage scenario using known volumes of artificial blood, the accuracy of gravimetric measurement was compared with visual estimation made by delivery suite staff. In the clinical observation study, the blood volume lost during postpartum haemorrhage was measured gravimetrically according to our routine institutional protocol and was correlated with fall in haemoglobin. The main outcome measure was the accuracy of gravimetric measurement of blood loss. Validation exercise: the mean percentage error of gravimetrically measured blood volume was 4.0±2.7% compared to visually estimated blood volume with a mean percentage error of 34.7±32.1%. Clinical observation study: 356 out of 6187 deliveries were identified as having major postpartum haemorrhage. The correlation coefficient between measured blood loss and corrected fall in haemoglobin for all patients was 0.77; correlation was stronger (0.80) for postpartum haemorrhage >1500mL, and similar during routine and out-of-hours working. The accuracy of the gravimetric method was confirmed in simulated postpartum haemorrhage. The clinical study shows that gravimetric measurement of blood loss is correlated with the fall in haemoglobin in postpartum haemorrhage where blood loss exceeds 1500mL. The method is simple to perform, requires only basic equipment, and can be taught and used by all maternity services during major postpartum haemorrhage. Copyright © 2014 Elsevier Ltd. All rights reserved.

  9. Long-term behaviour and cross-correlation water quality analysis of the River Elbe, Germany.

    PubMed

    Lehmann, A; Rode, M

    2001-06-01

    This study analyses weekly data samples from the river Elbe at Magdeburg between 1984 and 1996 to investigate the changes in metabolism and water quality in the river Elbe since the German reunification in 1990. Modelling water quality variables by autoregressive component models and ARIMA models reveals the improvement of water quality due to the reduction of waste water emissions since 1990. The models are used to determine the long-term and seasonal behaviour of important water quality variables. Organic and heavy metal pollution parameters showed a significant decrease since 1990, however, no significant change of chlorophyll-a as a measure for primary production could be found. A new procedure for testing the significance of a sample correlation coefficient is discussed, which is able to detect spurious sample correlation coefficients without making use of time-consuming prewhitening. The cross-correlation analysis is applied to hydrophysical, biological, and chemical water quality variables of the river Elbe since 1984. Special emphasis is laid on the detection of spurious sample correlation coefficients.

  10. Generalization of Clustering Coefficients to Signed Correlation Networks

    PubMed Central

    Costantini, Giulio; Perugini, Marco

    2014-01-01

    The recent interest in network analysis applications in personality psychology and psychopathology has put forward new methodological challenges. Personality and psychopathology networks are typically based on correlation matrices and therefore include both positive and negative edge signs. However, some applications of network analysis disregard negative edges, such as computing clustering coefficients. In this contribution, we illustrate the importance of the distinction between positive and negative edges in networks based on correlation matrices. The clustering coefficient is generalized to signed correlation networks: three new indices are introduced that take edge signs into account, each derived from an existing and widely used formula. The performances of the new indices are illustrated and compared with the performances of the unsigned indices, both on a signed simulated network and on a signed network based on actual personality psychology data. The results show that the new indices are more resistant to sample variations in correlation networks and therefore have higher convergence compared with the unsigned indices both in simulated networks and with real data. PMID:24586367

  11. Investigation on the heat transfer characteristics during flow boiling of liquefied natural gas in a vertical micro-fin tube

    NASA Astrophysics Data System (ADS)

    Xu, Bin; Shi, Yumei; Chen, Dongsheng

    2014-03-01

    This paper presents an experimental investigation on the heat transfer characteristics of liquefied natural gas flow boiling in a vertical micro-fin tube. The effect of heat flux, mass flux and inlet pressure on the flow boiling heat transfer coefficients was analyzed. The Kim, Koyama, and two kinds of Wellsandt correlations with different Ftp coefficients were used to predict the flow boiling heat transfer coefficients. The predicted results showed that the Koyama correlation was the most accurate over the range of experimental conditions.

  12. Statistical analysis of CSP plants by simulating extensive meteorological series

    NASA Astrophysics Data System (ADS)

    Pavón, Manuel; Fernández, Carlos M.; Silva, Manuel; Moreno, Sara; Guisado, María V.; Bernardos, Ana

    2017-06-01

    The feasibility analysis of any power plant project needs the estimation of the amount of energy it will be able to deliver to the grid during its lifetime. To achieve this, its feasibility study requires a precise knowledge of the solar resource over a long term period. In Concentrating Solar Power projects (CSP), financing institutions typically requires several statistical probability of exceedance scenarios of the expected electric energy output. Currently, the industry assumes a correlation between probabilities of exceedance of annual Direct Normal Irradiance (DNI) and energy yield. In this work, this assumption is tested by the simulation of the energy yield of CSP plants using as input a 34-year series of measured meteorological parameters and solar irradiance. The results of this work show that, even if some correspondence between the probabilities of exceedance of annual DNI values and energy yields is found, the intra-annual distribution of DNI may significantly affect this correlation. This result highlights the need of standardized procedures for the elaboration of representative DNI time series representative of a given probability of exceedance of annual DNI.

  13. Relationship between photoreceptor outer segment length and visual acuity in diabetic macular edema.

    PubMed

    Forooghian, Farzin; Stetson, Paul F; Meyer, Scott A; Chew, Emily Y; Wong, Wai T; Cukras, Catherine; Meyerle, Catherine B; Ferris, Frederick L

    2010-01-01

    The purpose of this study was to quantify photoreceptor outer segment (PROS) length in 27 consecutive patients (30 eyes) with diabetic macular edema using spectral domain optical coherence tomography and to describe the correlation between PROS length and visual acuity. Three spectral domain-optical coherence tomography scans were performed on all eyes during each session using Cirrus HD-OCT. A prototype algorithm was developed for quantitative assessment of PROS length. Retinal thicknesses and PROS lengths were calculated for 3 parameters: macular grid (6 x 6 mm), central subfield (1 mm), and center foveal point (0.33 mm). Intrasession repeatability was assessed using coefficient of variation and intraclass correlation coefficient. The association between retinal thickness and PROS length with visual acuity was assessed using linear regression and Pearson correlation analyses. The main outcome measures include intrasession repeatability of macular parameters and correlation of these parameters with visual acuity. Mean retinal thickness and PROS length were 298 mum to 381 microm and 30 microm to 32 mum, respectively, for macular parameters assessed in this study. Coefficient of variation values were 0.75% to 4.13% for retinal thickness and 1.97% to 14.01% for PROS length. Intraclass correlation coefficient values were 0.96 to 0.99 and 0.73 to 0.98 for retinal thickness and PROS length, respectively. Slopes from linear regression analyses assessing the association of retinal thickness and visual acuity were not significantly different from 0 (P > 0.20), whereas the slopes of PROS length and visual acuity were significantly different from 0 (P < 0.0005). Correlation coefficients for macular thickness and visual acuity ranged from 0.13 to 0.22, whereas coefficients for PROS length and visual acuity ranged from -0.61 to -0.81. Photoreceptor outer segment length can be quantitatively assessed using Cirrus HD-OCT. Although the intrasession repeatability of PROS measurements was less than that of macular thickness measurements, the stronger correlation of PROS length with visual acuity suggests that the PROS measures may be more directly related to visual function. Photoreceptor outer segment length may be a useful physiologic outcome measure, both clinically and as a direct assessment of treatment effects.

  14. Scale-Free Nonparametric Factor Analysis: A User-Friendly Introduction with Concrete Heuristic Examples.

    ERIC Educational Resources Information Center

    Mittag, Kathleen Cage

    Most researchers using factor analysis extract factors from a matrix of Pearson product-moment correlation coefficients. A method is presented for extracting factors in a non-parametric way, by extracting factors from a matrix of Spearman rho (rank correlation) coefficients. It is possible to factor analyze a matrix of association such that…

  15. Modifying Spearman's Attenuation Equation to Yield Partial Corrections for Measurement Error--With Application to Sample Size Calculations

    ERIC Educational Resources Information Center

    Nicewander, W. Alan

    2018-01-01

    Spearman's correction for attenuation (measurement error) corrects a correlation coefficient for measurement errors in either-or-both of two variables, and follows from the assumptions of classical test theory. Spearman's equation removes all measurement error from a correlation coefficient which translates into "increasing the reliability of…

  16. Sample Size Calculation for Estimating or Testing a Nonzero Squared Multiple Correlation Coefficient

    ERIC Educational Resources Information Center

    Krishnamoorthy, K.; Xia, Yanping

    2008-01-01

    The problems of hypothesis testing and interval estimation of the squared multiple correlation coefficient of a multivariate normal distribution are considered. It is shown that available one-sided tests are uniformly most powerful, and the one-sided confidence intervals are uniformly most accurate. An exact method of calculating sample size to…

  17. A Note on the Reliability Coefficients for Item Response Model-Based Ability Estimates

    ERIC Educational Resources Information Center

    Kim, Seonghoon

    2012-01-01

    Assuming item parameters on a test are known constants, the reliability coefficient for item response theory (IRT) ability estimates is defined for a population of examinees in two different ways: as (a) the product-moment correlation between ability estimates on two parallel forms of a test and (b) the squared correlation between the true…

  18. Correlation between National Influenza Surveillance Data and Search Queries from Mobile Devices and Desktops in South Korea

    PubMed Central

    Seo, Dong-Woo; Sohn, Chang Hwan; Kim, Sung-Hoon; Ryoo, Seung Mok; Lee, Yoon-Seon; Lee, Jae Ho; Kim, Won Young; Lim, Kyoung Soo

    2016-01-01

    Background Digital surveillance using internet search queries can improve both the sensitivity and timeliness of the detection of a health event, such as an influenza outbreak. While it has recently been estimated that the mobile search volume surpasses the desktop search volume and mobile search patterns differ from desktop search patterns, the previous digital surveillance systems did not distinguish mobile and desktop search queries. The purpose of this study was to compare the performance of mobile and desktop search queries in terms of digital influenza surveillance. Methods and Results The study period was from September 6, 2010 through August 30, 2014, which consisted of four epidemiological years. Influenza-like illness (ILI) and virologic surveillance data from the Korea Centers for Disease Control and Prevention were used. A total of 210 combined queries from our previous survey work were used for this study. Mobile and desktop weekly search data were extracted from Naver, which is the largest search engine in Korea. Spearman’s correlation analysis was used to examine the correlation of the mobile and desktop data with ILI and virologic data in Korea. We also performed lag correlation analysis. We observed that the influenza surveillance performance of mobile search queries matched or exceeded that of desktop search queries over time. The mean correlation coefficients of mobile search queries and the number of queries with an r-value of ≥ 0.7 equaled or became greater than those of desktop searches over the four epidemiological years. A lag correlation analysis of up to two weeks showed similar trends. Conclusion Our study shows that mobile search queries for influenza surveillance have equaled or even become greater than desktop search queries over time. In the future development of influenza surveillance using search queries, the recognition of changing trend of mobile search data could be necessary. PMID:27391028

  19. Correlation between National Influenza Surveillance Data and Search Queries from Mobile Devices and Desktops in South Korea.

    PubMed

    Shin, Soo-Yong; Kim, Taerim; Seo, Dong-Woo; Sohn, Chang Hwan; Kim, Sung-Hoon; Ryoo, Seung Mok; Lee, Yoon-Seon; Lee, Jae Ho; Kim, Won Young; Lim, Kyoung Soo

    2016-01-01

    Digital surveillance using internet search queries can improve both the sensitivity and timeliness of the detection of a health event, such as an influenza outbreak. While it has recently been estimated that the mobile search volume surpasses the desktop search volume and mobile search patterns differ from desktop search patterns, the previous digital surveillance systems did not distinguish mobile and desktop search queries. The purpose of this study was to compare the performance of mobile and desktop search queries in terms of digital influenza surveillance. The study period was from September 6, 2010 through August 30, 2014, which consisted of four epidemiological years. Influenza-like illness (ILI) and virologic surveillance data from the Korea Centers for Disease Control and Prevention were used. A total of 210 combined queries from our previous survey work were used for this study. Mobile and desktop weekly search data were extracted from Naver, which is the largest search engine in Korea. Spearman's correlation analysis was used to examine the correlation of the mobile and desktop data with ILI and virologic data in Korea. We also performed lag correlation analysis. We observed that the influenza surveillance performance of mobile search queries matched or exceeded that of desktop search queries over time. The mean correlation coefficients of mobile search queries and the number of queries with an r-value of ≥ 0.7 equaled or became greater than those of desktop searches over the four epidemiological years. A lag correlation analysis of up to two weeks showed similar trends. Our study shows that mobile search queries for influenza surveillance have equaled or even become greater than desktop search queries over time. In the future development of influenza surveillance using search queries, the recognition of changing trend of mobile search data could be necessary.

  20. An efficient sensitivity analysis method for modified geometry of Macpherson suspension based on Pearson correlation coefficient

    NASA Astrophysics Data System (ADS)

    Shojaeefard, Mohammad Hasan; Khalkhali, Abolfazl; Yarmohammadisatri, Sadegh

    2017-06-01

    The main purpose of this paper is to propose a new method for designing Macpherson suspension, based on the Sobol indices in terms of Pearson correlation which determines the importance of each member on the behaviour of vehicle suspension. The formulation of dynamic analysis of Macpherson suspension system is developed using the suspension members as the modified links in order to achieve the desired kinematic behaviour. The mechanical system is replaced with an equivalent constrained links and then kinematic laws are utilised to obtain a new modified geometry of Macpherson suspension. The equivalent mechanism of Macpherson suspension increased the speed of analysis and reduced its complexity. The ADAMS/CAR software is utilised to simulate a full vehicle, Renault Logan car, in order to analyse the accuracy of modified geometry model. An experimental 4-poster test rig is considered for validating both ADAMS/CAR simulation and analytical geometry model. Pearson correlation coefficient is applied to analyse the sensitivity of each suspension member according to vehicle objective functions such as sprung mass acceleration, etc. Besides this matter, the estimation of Pearson correlation coefficient between variables is analysed in this method. It is understood that the Pearson correlation coefficient is an efficient method for analysing the vehicle suspension which leads to a better design of Macpherson suspension system.

  1. A Millennial-length Reconstruction of the Western Pacific Pattern with Associated Paleoclimate

    NASA Astrophysics Data System (ADS)

    Wright, W. E.; Guan, B. T.; Wei, K.

    2010-12-01

    The Western Pacific Pattern (WP) is a lesser known 500 hPa pressure pattern similar to the NAO or PNA. As defined, the poles of the WP index are centered on 60°N over the Kamchatka peninsula and the neighboring Pacific and on 32.5°N over the western north Pacific. However, the area of influence for the southern half of the dipole includes a wide swath from East Asia, across Taiwan, through the Philippine Sea, to the western north Pacific. Tree rings of Taiwanese Chamaecyparis obtusa var. formosana in this extended region show significant correlation with the WP, and with local temperature. The WP is also significantly correlated with atmospheric temperatures over Taiwan, especially at 850hPa and 700 hPa, pressure levels that bracket the tree site. Spectral analysis indicates that variations in the WP occur at relatively high frequency, with most power at less than 5 years. Simple linear regression against high frequency variants of the tree-ring chronology yielded the most significant correlation coefficients. Two reconstructions are presented. The first uses a tree-ring time series produced as the first intrinsic mode function (IMF) from an Ensemble Empirical Mode Decomposition (EEMD), based on the Hilbert-Huang Transform. The significance of the regression using the EEMD-derived time series was much more significant than time series produced using traditional high pass filtering. The second also uses the first IMF of a tree-ring time series, but the dataset was first sorted and partitioned at a specified quantile prior to EEMD decomposition, with the mean of the partitioned data forming the input to the EEMD. The partitioning was done to filter out the less climatically sensitive tree rings, a common problem with shade tolerant trees. Time series statistics indicate that the first reconstruction is reliable to 1241 of the Common Era. Reliability of the second reconstruction is dependent on the development of statistics related to the quantile partitioning, and the consequent reduction in sample depth. However, the correlation coefficients from regressions over the instrumental period greatly exceed those from any other method of chronology generation, and so the technique holds promise. Additional atmospheric parameters having significant correlations against the WPO and tree ring time series with similar spatial patterns are also presented. These include vertical wind shear (850hPa-700hPa) over the northern Philippines and the Philippine Sea, surface Omega and 850hPa v-winds over the East China Sea, Japan and Taiwan. Possible links to changes in the subtropical jet stream will also be discussed.

  2. Experimental investigation of heat transfer coefficient of mini-channel PCHE (printed circuit heat exchanger)

    NASA Astrophysics Data System (ADS)

    Kwon, Dohoon; Jin, Lingxue; Jung, WooSeok; Jeong, Sangkwon

    2018-06-01

    Heat transfer coefficient of a mini-channel printed circuit heat exchanger (PCHE) with counter-flow configuration is investigated. The PCHE used in the experiments is two layered (10 channels per layer) and has the hydraulic diameter of 1.83 mm. Experiments are conducted under various cryogenic heat transfer conditions: single-phase, boiling and condensation heat transfer. Heat transfer coefficients of each experiments are presented and compared with established correlations. In the case of the single-phase experiment, empiricial correlation of modified Dittus-Boelter correlation was proposed, which predicts the experimental results with 5% error at Reynolds number range from 8500 to 17,000. In the case of the boiling experiment, film boiling phenomenon occurred dominantly due to large temperature difference between the hot side and the cold side fluids. Empirical correlation is proposed which predicts experimental results with 20% error at Reynolds number range from 2100 to 2500. In the case of the condensation experiment, empirical correlation of modified Akers correlation was proposed, which predicts experimental results with 10% error at Reynolds number range from 3100 to 6200.

  3. Relationship between the percentage of body fat and surrogate indices of fatness in male and female Polish active and sedentary students.

    PubMed

    Lutoslawska, Grażyna; Malara, Marzena; Tomaszewski, Paweł; Mazurek, Krzysztof; Czajkowska, Anna; Kęska, Anna; Tkaczyk, Joanna

    2014-05-13

    Limited data have indicated that body mass index (BMI), waist circumference (WC), waist to hip ratio (WHR) and waist to height ratio (WHtR) of athletes and young adults provide misleading results concerning body fat content. This study was aimed at the evaluation of the relationship between different surrogate indices of fatness (BMI, WC, WHR, WHtR and body adiposity index (BAI)) with the percentage of body fat in Polish students with respect to their sex and physical activity. A total of 272 students volunteered to participate in the study. Of these students, 177 physical education students (90 males and 87 females) were accepted as active (physical activity of 7 to 9 hours/week); and 95 students of other specializations (49 males and 46 females) were accepted as sedentary (physical activity of 1.5 hours/week). Weight, height, waist and hip circumferences were measured, and BMI, WHR, WHtR and BAI were calculated. Body fat percentage was assessed using four skinfold measurements. Classification of fatness according to the BMI and the percentage of body fat have indicated that BMI overestimates fatness in lean subjects (active men and women, sedentary men), but underestimates body fat in obese subjects (sedentary women). In all groups, BMI, WHR, WHtR and BAI were significantly correlated with the percentage of body fat (with the exception of WHR and hip circumference in active and sedentary women, respectively). However, coefficients of determination not exceeding 50% and Lin's concordance correlation coefficients lower than 0.9 indicated no relationship between measured and calculated body fat. The findings in the present study support the concept that irrespective of physical activity and sex none of the calculated indices of fatness are useful in the determination of body fat in young adults. Thus, it seems that easily calculated indices may contribute to distorted body image and unhealthy dietary habits observed in many young adults in Western countries, but also in female athletes.

  4. A behaviourally anchored rating scale for evaluating the use of the WHO surgical safety checklist: development and initial evaluation of the WHOBARS.

    PubMed

    Devcich, Daniel A; Weller, Jennifer; Mitchell, Simon J; McLaughlin, Scott; Barker, Lauren; Rudolph, Jenny W; Raemer, Daniel B; Zammert, Martin; Singer, Sara J; Torrie, Jane; Frampton, Chris Ma; Merry, Alan F

    2016-10-01

    Realising the full potential of the WHO Surgical Safety Checklist (SSC) to reduce perioperative harm requires the constructive engagement of all operating room (OR) team members during its administration. To facilitate research on SSC implementation, a valid and reliable instrument is needed for measuring OR team behaviours during its administration. We developed a behaviourally anchored rating scale (BARS) for this purpose. We used a modified Delphi process, involving 16 subject matter experts, to compile a BARS with behavioural domains applicable to all three phases of the SSC. We evaluated the instrument in 80 adult OR cases and 30 simulated cases using two medical student raters and seven expert raters, respectively. Intraclass correlation coefficients were calculated to assess inter-rater reliability. Internal consistency and instrument discrimination were explored. Sample size estimates for potential study designs using the instrument were calculated. The Delphi process resulted in a BARS instrument (the WHOBARS) with five behavioural domains. Intraclass correlation coefficients calculated from the OR cases exceeded 0.80 for 80% of the instrument's domains across the SSC phases. The WHOBARS showed high internal consistency across the three phases of the SSC and ability to discriminate among surgical cases in both clinical and simulated settings. Fewer than 20 cases per group would be required to show a difference of 1 point between groups in studies of the SSC, where α=0.05 and β=0.8. We have developed a generic instrument for comprehensively rating the administration of the SSC and informing initiatives to realise its full potential. We have provided data supporting its capacity for discrimination, internal consistency and inter-rater reliability. Further psychometric evaluation is warranted. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

  5. A comparison of various "housekeeping" probes for northern analysis of normal and osteoarthritic articular cartilage RNA.

    PubMed

    Matyas, J R; Huang, D; Adams, M E

    1999-01-01

    Several approaches are commonly used to normalize variations in RNA loading on Northern blots, including: ethidium bromide (EthBr) fluorescence of 18S or 28S rRNA or autoradiograms of radioactive probes hybridized with constitutively expressed RNAs such as elongation factor-1alpha (ELF), glyceraldehyde-3-phosphate dehydrogenase (G3PDH), actin, 18S or 28S rRNA, or others. However, in osteoarthritis (OA) the amount of total RNA changes significantly and none of these RNAs has been clearly demonstrated to be expressed at a constant level, so it is unclear if any of these approaches can be used reliably for normalizing RNA extracted from osteoarthritic cartilage. Total RNA was extracted from normal and osteoarthritic cartilage and assessed by EthBr fluorescence. RNA was then transferred to a nylon membrane hybridized with radioactive probes for ELF, G3PDH, Max, actin, and an oligo-dT probe. The autoradiographic signal across the six lanes of a gel was quantified by scanning densitometry. When compared on the basis of total RNA, the coefficient of variation was lowest for 28S ethidium bromide fluorescence and oligo-dT (approximately 7%), followed by 18S ethidium bromide fluorescence and G3PDH (approximately 13%). When these values were normalized to DNA concentration, the coefficient of variation exceeded 50% for all signals. Total RNA and the signals for 18S, 28S rRNA, and oligo-dT all correlated highly. These data indicate that osteoarthritic chondrocytes express similar ratios of mRNA to rRNA and mRNA to total RNA as do normal chondrocytes. Of all the "housekeeping" probes, G3PDH correlated best with the measurements of RNA. All of these "housekeeping" probes are expressed at greater levels by osteoarthritic chondrocytes when compared with normal chondrocytes. Thus, while G3PDH is satisfactory for evaluating the amount of RNA loaded, its level of expression is not the same in normal and osteoarthritic chondrocytes.

  6. Effect of endorectal balloon positioning errors on target deformation and dosimetric quality during prostate SBRT

    NASA Astrophysics Data System (ADS)

    Jones, Bernard L.; Gan, Gregory; Kavanagh, Brian; Miften, Moyed

    2013-11-01

    An inflatable endorectal balloon (ERB) is often used during stereotactic body radiation therapy (SBRT) for treatment of prostate cancer in order to reduce both intrafraction motion of the target and risk of rectal toxicity. However, the ERB can exert significant force on the prostate, and this work assessed the impact of ERB position errors on deformation of the prostate and treatment dose metrics. Seventy-one cone-beam computed tomography (CBCT) image datasets of nine patients with clinical stage T1cN0M0 prostate cancer were studied. An ERB (Flexi-Cuff, EZ-EM, Westbury, NY) inflated with 60 cm3 of air was used during simulation and treatment, and daily kilovoltage (kV) CBCT imaging was performed to localize the prostate. The shape of the ERB in each CBCT was analyzed to determine errors in position, size, and shape. A deformable registration algorithm was used to track the dose received by (and deformation of) the prostate, and dosimetric values such as D95, PTV coverage, and Dice coefficient for the prostate were calculated. The average balloon position error was 0.5 cm in the inferior direction, with errors ranging from 2 cm inferiorly to 1 cm superiorly. The prostate was deformed primarily in the AP direction, and tilted primarily in the anterior-posterior/superior-inferior plane. A significant correlation was seen between errors in depth of ERB insertion (DOI) and mean voxel-wise deformation, prostate tilt, Dice coefficient, and planning-to-treatment prostate inter-surface distance (p < 0.001). Dosimetrically, DOI is negatively correlated with prostate D95 and PTV coverage (p < 0.001). For the model of ERB studied, error in ERB position can cause deformations in the prostate that negatively affect treatment, and this additional aspect of setup error should be considered when ERBs are used for prostate SBRT. Before treatment, the ERB position should be verified, and the ERB should be adjusted if the error is observed to exceed tolerable values.

  7. Validation of a self-administered web-based 24-hour dietary recall among pregnant women.

    PubMed

    Savard, Claudia; Lemieux, Simone; Lafrenière, Jacynthe; Laramée, Catherine; Robitaille, Julie; Morisset, Anne-Sophie

    2018-04-23

    The use of valid dietary assessment methods is crucial to analyse adherence to dietary recommendations among pregnant women. This study aims to assess the relative validity of a self-administered Web-based 24-h dietary recall, the R24W, against a pen-paper 3-day food record (FR) among pregnant women. Sixty (60) pregnant women recruited at 9.3 ± 0.7 weeks of pregnancy in Quebec City completed, at each trimester, 3 R24W and a 3-day FR. Mean energy and nutrient intakes reported by both tools were compared using paired Student T-Tests. Pearson correlations were used to analyze the association between both methods. Agreement between the two methods was evaluated using cross-classification analyses, weighted kappa coefficients and Bland-Altman analyses. Pearson correlation coefficients were all significant, except for vitamin B 12 (r = 0.03; p = 0.83) and ranged from 0.27 to 0.76 (p < 0.05). Differences between mean intakes assessed by the R24W and the FR did not exceed 10% in 19 variables and were not significant for 16 out of 26 variables. In cross-classification analyses, the R24W ranked, on average, 79.1% of participants in the same or adjacent quartiles as the FR. Compared to a 3-day FR, the R24W is a valid method to assess intakes of energy and most nutrients but may be less accurate in the evaluation of intakes of fat (as a proportion of energy intake), vitamin D, zinc and folic acid. During pregnancy, the R24W was a more accurate tool at a group-level than at an individual-level and should, therefore, be used in an epidemiological rather than a clinical setting. The R24W may be particularly valuable as a tool used in cohort studies to provide valid information on pregnant women's dietary intakes and facilitate evaluation of associations between diet and adverse pregnancy outcomes.

  8. Weak data do not make a free lunch, only a cheap meal

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Luo, Zhipu; Rajashankar, Kanagalaghatta; Dauter, Zbigniew, E-mail: dauter@anl.gov

    2014-02-01

    Refinement and analysis of four structures with various data resolution cutoffs suggests that at present there are no reliable criteria for judging the diffraction data resolution limit and the condition I/σ(I) = 2.0 is reasonable. However, extending the limit by about 0.2 Å beyond the resolution defined by this threshold does not deteriorate the quality of refined structures and in some cases may be beneficial. Four data sets were processed at resolutions significantly exceeding the criteria traditionally used for estimating the diffraction data resolution limit. The analysis of these data and the corresponding model-quality indicators suggests that the criteria ofmore » resolution limits widely adopted in the past may be somewhat conservative. Various parameters, such as R{sub merge} and I/σ(I), optical resolution and the correlation coefficients CC{sub 1/2} and CC*, can be used for judging the internal data quality, whereas the reliability factors R and R{sub free} as well as the maximum-likelihood target values and real-space map correlation coefficients can be used to estimate the agreement between the data and the refined model. However, none of these criteria provide a reliable estimate of the data resolution cutoff limit. The analysis suggests that extension of the maximum resolution by about 0.2 Å beyond the currently adopted limit where the I/σ(I) value drops to 2.0 does not degrade the quality of the refined structural models, but may sometimes be advantageous. Such an extension may be particularly beneficial for significantly anisotropic diffraction. Extension of the maximum resolution at the stage of data collection and structure refinement is cheap in terms of the required effort and is definitely more advisable than accepting a too conservative resolution cutoff, which is unfortunately quite frequent among the crystal structures deposited in the Protein Data Bank.« less

  9. Histogram analysis parameters of apparent diffusion coefficient reflect tumor cellularity and proliferation activity in head and neck squamous cell carcinoma

    PubMed Central

    Winter, Karsten; Richter, Cindy; Hoehn, Anna-Kathrin

    2018-01-01

    Our purpose was to analyze associations between apparent diffusion coefficient (ADC) histogram analysis parameters and histopathologicalfeatures in head and neck squamous cell carcinoma (HNSCC). The study involved 32 patients with primary HNSCC. For every tumor, the following histogram analysis parameters were calculated: ADCmean, ADCmax, ADCmin, ADCmedian, ADCmode, P10, P25, P75, P90, kurtosis, skewness, and entropy. Furthermore, proliferation index KI 67, cell count, total and average nucleic areas were estimated. Spearman's correlation coefficient (p) was used to analyze associations between investigated parameters. In overall sample, all ADC values showed moderate inverse correlations with KI 67. All ADC values except ADCmax correlated inversely with tumor cellularity. Slightly correlations were identified between total/average nucleic area and ADCmean, ADCmin, ADCmedian, and P25. In G1/2 tumors, only ADCmode correlated well with Ki67. No statistically significant correlations between ADC parameters and cellularity were found. In G3 tumors, Ki 67 correlated with all ADC parameters except ADCmode. Cell count correlated well with all ADC parameters except ADCmax. Total nucleic area correlated inversely with ADCmean, ADCmin, ADCmedian, P25, and P90. ADC histogram parameters reflect proliferation potential and cellularity in HNSCC. The associations between histopathology and imaging depend on tumor grading. PMID:29805759

  10. Fast-GPU-PCC: A GPU-Based Technique to Compute Pairwise Pearson's Correlation Coefficients for Time Series Data-fMRI Study.

    PubMed

    Eslami, Taban; Saeed, Fahad

    2018-04-20

    Functional magnetic resonance imaging (fMRI) is a non-invasive brain imaging technique, which has been regularly used for studying brain’s functional activities in the past few years. A very well-used measure for capturing functional associations in brain is Pearson’s correlation coefficient. Pearson’s correlation is widely used for constructing functional network and studying dynamic functional connectivity of the brain. These are useful measures for understanding the effects of brain disorders on connectivities among brain regions. The fMRI scanners produce huge number of voxels and using traditional central processing unit (CPU)-based techniques for computing pairwise correlations is very time consuming especially when large number of subjects are being studied. In this paper, we propose a graphics processing unit (GPU)-based algorithm called Fast-GPU-PCC for computing pairwise Pearson’s correlation coefficient. Based on the symmetric property of Pearson’s correlation, this approach returns N ( N − 1 ) / 2 correlation coefficients located at strictly upper triangle part of the correlation matrix. Storing correlations in a one-dimensional array with the order as proposed in this paper is useful for further usage. Our experiments on real and synthetic fMRI data for different number of voxels and varying length of time series show that the proposed approach outperformed state of the art GPU-based techniques as well as the sequential CPU-based versions. We show that Fast-GPU-PCC runs 62 times faster than CPU-based version and about 2 to 3 times faster than two other state of the art GPU-based methods.

  11. Does Preoperative Platelet Function Predict Bleeding in Patients Undergoing Off Pump Coronary Artery Bypass Surgery?

    PubMed

    Berger, Peter B; Kirchner, H Lester; Wagner, Eric S; Ismail-Sayed, Ibrahim; Yahya, Salma; Benoit, Charles; Blankenship, James C; Carter, Russell; Casale, Alfred S; Green, Sandy M; Scott, Thomas D; Skelding, Kimberly A; Woods, Edward; Henry, Yvette M

    2015-06-01

    We sought to examine the relationship between preoperative platelet function and perioperative bleeding in patients undergoing CABG. There are many ways to measure platelet aggregability. Little is known about their correlations with one another, or with bleeding. We prospectively studied 50 patients undergoing a first isolated off-pump CABG. Thirty-four were exposed to a thienopyridine prior to surgery; 16 were not. Preoperative platelet function was measured by VerifyNow®, TEG®, AggreGuide™, Plateletworks®, vasodilator-stimulated phosphoprotein (VASP) phosphorylation, and light transmission aggregometry. Bleeding was assessed 2 ways: drop from pre- to nadir postoperative hematocrit, and chest tube drainage. Correlation coefficients were calculated using Spearman's rank-order correlation. Mean age was 62 years. Patient characteristics and surgical details were similar between the thienopyridine-exposed and non-exposed patients. The correlation coefficients between the 4 point-of-care platelet function measurements and hematocrit change ranged from -0.2274 to 0.2882. Only Plateletworks® correlated with drop in hematocrit (r = 0.2882, P = 0.0470). The correlation coefficients between each of the 4 point-of-care platelet function tests and the chest tube drainage were also poor, ranging from -0.3073 to 0.2272. Both AggreGuide™ (r = -0.3073, P = 0.0317) and VASP (r = -0.3187, P = 0.0272) were weakly but significantly correlated with chest tube drainage. The correlation among the 4 point-of-care platelet function measurements was poor, with coefficients ranging from -0.2504 to 0.1968. We observed little correlation among 4 platelet function tests, and between those assays and perioperative bleeding defined 2 different ways. Whether any of these assays should be used to guide decision making in individual patients is unclear. © 2015, Wiley Periodicals, Inc.

  12. Relationship between plethysmographic waveform changes and hemodynamic variables in anesthetized, mechanically ventilated patients undergoing continuous cardiac output monitoring.

    PubMed

    Thiele, Robert H; Colquhoun, Douglas A; Patrie, James; Nie, Sarah H; Huffmyer, Julie L

    2011-12-01

    To assess the relation between photoplethysmographically-derived parameters and invasively-determined hemodynamic variables. After induction of anesthesia and placement of a Swan-Ganz CCOmbo catheter, a Nonin OEM III probe was placed on each patient's earlobe. Photoplethysmographic signals were recorded in conjunction with cardiac output. Photoplethysmographic metrics (amplitude of absorbance waveform, maximal slope of absorbance waveform, area under the curve, and width) were calculated offline and compared with invasively determined hemodynamic variables. Subject-specific associations between each dependent and independent variable pair were summarized on a per-subject basis by the nonparametric Spearman rank correlation coefficient. The bias-corrected accelerated bootstrap resampling procedure of Efron and Tibshirani was used to obtain a 95% confidence interval for the median subject-specific correlation coefficient, and Wilcoxon sign-rank tests were conducted to test the null hypothesis that the median of the subject-specific correlation coefficients were equal to 0. University hospital. Eighteen patients undergoing coronary artery bypass graft surgery. Placement of a Swan-Ganz CCOmbo catheter and a Nonin OEM III pulse oximetry probe. There was a positive, statistically significant correlation between stroke volume and width (median correlation coefficient, 0.29; confidence interval, 0.01-0.46; p = 0.034). The concordance between changes in stroke volume and changes in width was 53%. No other correlations achieved statistical significance. This study was unable to reproduce the results of prior studies. Only stroke volume and photoplethysmographic width were correlated in this study; however, the correlation and concordance (based on analysis of a 4-quadrant plot) were too weak to be clinically useful. Future studies in patients undergoing low-to-moderate risk surgery may result in improved correlations and clinical utility. Copyright © 2011 Elsevier Inc. All rights reserved.

  13. Relation between heat of vaporization, ion transport, molar volume, and cation-anion binding energy for ionic liquids.

    PubMed

    Borodin, Oleg

    2009-09-10

    A number of correlations between heat of vaporization (H(vap)), cation-anion binding energy (E(+/-)), molar volume (V(m)), self-diffusion coefficient (D), and ionic conductivity for 29 ionic liquids have been investigated using molecular dynamics (MD) simulations that employed accurate and validated many-body polarizable force fields. A significant correlation between D and H(vap) has been found, while the best correlation was found for -log(DV(m)) vs H(vap) + 0.28E(+/-). A combination of enthalpy of vaporization and a fraction of the cation-anion binding energy was suggested as a measure of the effective cohesive energy for ionic liquids. A deviation of some ILs from the reported master curve is explained based upon ion packing and proposed diffusion pathways. No general correlations were found between the ion diffusion coefficient and molecular volume or the diffusion coefficient and cation/anion binding energy.

  14. Long-range correlations and charge transport properties of DNA sequences

    NASA Astrophysics Data System (ADS)

    Liu, Xiao-liang; Ren, Yi; Xie, Qiong-tao; Deng, Chao-sheng; Xu, Hui

    2010-04-01

    By using Hurst's analysis and transfer approach, the rescaled range functions and Hurst exponents of human chromosome 22 and enterobacteria phage lambda DNA sequences are investigated and the transmission coefficients, Landauer resistances and Lyapunov coefficients of finite segments based on above genomic DNA sequences are calculated. In a comparison with quasiperiodic and random artificial DNA sequences, we find that λ-DNA exhibits anticorrelation behavior characterized by a Hurst exponent 0.5

  15. Research and Development of Methods for Estimating Physicochemical Properties of Organic Compounds of Environmental Concern

    DTIC Science & Technology

    1979-02-01

    coefficient (at equilibrium) when hysteresis is apparent. 6. Coefficient n in Freundlich equation for 1/n soil or sediment adsorption isotherms ýX - KC . 7...Biodegradation Chemical structures cal clasaes (e.g., Diffusion Correlations phenols). General Diffusion coefficients Equations terms for organic...OF THE FATE AND TRANSPORT OF ORGANIC CHEMICALS Adsorption coefficients: K, n* from Freundlich equation + Desorption coefficients: K’*, n’* from

  16. Waste-assimilation study of Koshkonong Creek below sewage-treatment plant at Sun Prairie, Wisconsin

    USGS Publications Warehouse

    Grant, R. Stephen

    1976-01-01

    A waste-load-assimilation study of a reach of Koshkonong Creek below the Sun Prairie, Wisconsin, sewage-treatment-plant outfall indicated that a high level of treatment would be required to meet Wisconsin water-quality standards. To maintain a minimum dissolved-oxygen concentration of 5 mg/liter during the critical summer low-flow period, 5-day carbonaceous biochemical-oxygen demand in waste discharges should not exceed 5 mg/liter and ammonium nitrogen should not exceed 1.5 mg/liter. Advanced treatment with denitrification is required because stream-reaeration coefficients are not high enough to offset deoxygenation caused by an abundance of attached biological slimes. The slimes apparently consumed dissolved oxygen at a rate of about 110 mg/liter per day at the time of the stream survey. During the critical summer low-flow period, natural stream discharge is very small compared to waste-water discharge , so benefits of dilution are insignificant. An evaluation of two proposed alternative waste-water discharge sites indicated that the present discharge site is hydraulically superior to these sites. Stream-reaeration coefficients used in the study were based on measurements using the radioactive-tracer method. (Woodard-USGS)

  17. TH-A-18C-03: Noise Correlation in CBCT Projection Data and Its Application for Noise Reduction in Low-Dose CBCT

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    ZHANG, H; Huang, J; Ma, J

    2014-06-15

    Purpose: To study the noise correlation properties of cone-beam CT (CBCT) projection data and to incorporate the noise correlation information to a statistics-based projection restoration algorithm for noise reduction in low-dose CBCT. Methods: In this study, we systematically investigated the noise correlation properties among detector bins of CBCT projection data by analyzing repeated projection measurements. The measurements were performed on a TrueBeam on-board CBCT imaging system with a 4030CB flat panel detector. An anthropomorphic male pelvis phantom was used to acquire 500 repeated projection data at six different dose levels from 0.1 mAs to 1.6 mAs per projection at threemore » fixed angles. To minimize the influence of the lag effect, lag correction was performed on the consecutively acquired projection data. The noise correlation coefficient between detector bin pairs was calculated from the corrected projection data. The noise correlation among CBCT projection data was then incorporated into the covariance matrix of the penalized weighted least-squares (PWLS) criterion for noise reduction of low-dose CBCT. Results: The analyses of the repeated measurements show that noise correlation coefficients are non-zero between the nearest neighboring bins of CBCT projection data. The average noise correlation coefficients for the first- and second- order neighbors are about 0.20 and 0.06, respectively. The noise correlation coefficients are independent of the dose level. Reconstruction of the pelvis phantom shows that the PWLS criterion with consideration of noise correlation (PWLS-Cor) results in a lower noise level as compared to the PWLS criterion without considering the noise correlation (PWLS-Dia) at the matched resolution. Conclusion: Noise is correlated among nearest neighboring detector bins of CBCT projection data. An accurate noise model of CBCT projection data can improve the performance of the statistics-based projection restoration algorithm for low-dose CBCT.« less

  18. Correlation analysis of a ground-water level monitoring network, Miami-Dade County, Florida

    USGS Publications Warehouse

    Prinos, Scott T.

    2005-01-01

    The U.S. Geological Survey cooperative ground-water monitoring program in Miami-Dade County, Florida, expanded from 4 to 98 continuously recording water-level monitoring wells during the 1939-2001 period. Network design was based on area specific assessments; however, no countywide statistical assessments of network coverage had been performed for the purpose of assessing network redundancy. To aid in the assessment of network redundancy, correlation analyses were performed using S-PLUS 2000 statistical analysis software for daily maximum water-level data from 98 monitoring wells for the November 1, 1973, to October 31, 2000 period. Because of the complexities of the hydrologic, water-supply, and water-management systems in Miami-Dade County and the changes that have occurred to these systems through time, spatial and temporal variations in the degree of correlation had to be considered. To assess temporal variation in correlation, water-level data from each well were subdivided by year and by wet and dry seasons. For each well, year, and season, correlation analyses were performed on the data from those wells that had available data. For selected wells, the resulting correlation coefficients from each year and season were plotted with respect to time. To assess spatial variation in correlation, the coefficients determined from the correlation analysis were averaged. These average wet- and dry-season correlation coefficients were plotted spatially using geographic information system software. Wells with water-level data that correlated with a coefficient of 0.95 or greater were almost always located in relatively close proximity to each other. Five areas were identified where the water-level data from wells within the area remained correlated with that of other wells in the area during the wet and dry seasons. These areas are located in or near the C-1 and C-102 basins (2 wells), in or near the C-6 and C-7 basins (2 wells), near the Florida Keys Aqueduct Authority Well Field (2 wells), near the Hialeah-Miami Springs Well Field (6 wells), and near the West Well Field (21 wells). Data from the remaining 65 wells (most of the wells in the network) generally were not correlated with those of other wells during both the wet and dry seasons with an average coefficient of 0.95 or greater for the comparison. Because many of the wells near the West Well Field and some near the Hialeah-Miami Springs Well Field had not been in operation for very long (most having been installed in 1994), the averaged correlation coefficients for these wells were often determined using only a few seasons of data. For the few instances where water-level data were found to be well correlated on average for a lengthy period of record, short-term declines in correlation were often identified. In general, it would be beneficial to compare data for longer periods of record than currently available.

  19. Fungible Correlation Matrices: A Method for Generating Nonsingular, Singular, and Improper Correlation Matrices for Monte Carlo Research.

    PubMed

    Waller, Niels G

    2016-01-01

    For a fixed set of standardized regression coefficients and a fixed coefficient of determination (R-squared), an infinite number of predictor correlation matrices will satisfy the implied quadratic form. I call such matrices fungible correlation matrices. In this article, I describe an algorithm for generating positive definite (PD), positive semidefinite (PSD), or indefinite (ID) fungible correlation matrices that have a random or fixed smallest eigenvalue. The underlying equations of this algorithm are reviewed from both algebraic and geometric perspectives. Two simulation studies illustrate that fungible correlation matrices can be profitably used in Monte Carlo research. The first study uses PD fungible correlation matrices to compare penalized regression algorithms. The second study uses ID fungible correlation matrices to compare matrix-smoothing algorithms. R code for generating fungible correlation matrices is presented in the supplemental materials.

  20. Property relationships of the physical infrastructure and the traffic flow networks

    NASA Astrophysics Data System (ADS)

    Zhou, Ta; Zou, Sheng-Rong; He, Da-Ren

    2010-03-01

    We studied both empirically and analytically the correlation between the degrees or the clustering coefficients, respectively, of the networks in the physical infrastructure and the traffic flow layers in three Chinese transportation systems. The systems are bus transportation systems in Beijing and Hangzhou, and the railway system in the mainland. It is found that the correlation between the degrees obey a linear function; while the correlation between the clustering coefficients obey a power law. A possible dynamic explanation on the rules is presented.

  1. Correlation and simple linear regression.

    PubMed

    Zou, Kelly H; Tuncali, Kemal; Silverman, Stuart G

    2003-06-01

    In this tutorial article, the concepts of correlation and regression are reviewed and demonstrated. The authors review and compare two correlation coefficients, the Pearson correlation coefficient and the Spearman rho, for measuring linear and nonlinear relationships between two continuous variables. In the case of measuring the linear relationship between a predictor and an outcome variable, simple linear regression analysis is conducted. These statistical concepts are illustrated by using a data set from published literature to assess a computed tomography-guided interventional technique. These statistical methods are important for exploring the relationships between variables and can be applied to many radiologic studies.

  2. [Study on influence between activated carbon property and immobilized biological activated carbon purification effect].

    PubMed

    Wang, Guang-zhi; Li, Wei-guang; He, Wen-jie; Han, Hong-da; Ding, Chi; Ma, Xiao-na; Qu, Yan-ming

    2006-10-01

    By means of immobilizing five kinds of activated carbon, we studied the influence between the chief activated carbon property items and immobilized bioactivated carbon (IBAC) purification effect with the correlation analysis. The result shows that the activated carbon property items which the correlation coefficient is up 0.7 include molasses, abrasion number, hardness, tannin, uniform coefficient, mean particle diameter and effective particle diameter; the activated carbon property items which the correlation coefficient is up 0.5 include pH, iodine, butane and tetrachloride. In succession, the partial correlation analysis shows that activated carbon property items mostly influencing on IBAC purification effect include molasses, hardness, abrasion number, uniform coefficient, mean particle diameter and effective particle diameter. The causation of these property items bringing influence on IBAC purification is that the activated carbon holes distribution (representative activated carbon property item is molasses) provides inhabitable location and adjust food for the dominance bacteria; the mechanical resist-crash property of activated carbon (representative activated carbon property items: abrasion number and hardness) have influence on the stability of biofilm; and the particle diameter size and distribution of activated carbon (representative activated carbon property items: uniform coefficient, mean particle diameter and effective particle diameter) can directly affect the force of water in IBAC filter bed, which brings influence on the dominance bacteria immobilizing on activated carbon.

  3. Ion-exclusion chromatography determination of organic acid in uridine 5'-monophosphate fermentation broth.

    PubMed

    Niu, Huanqing; Chen, Yong; Xie, Jingjing; Chen, Xiaochun; Bai, Jianxin; Wu, Jinglan; Liu, Dong; Ying, Hanjie

    2012-09-01

    Simultaneous determination of organic acids using ion-exclusion liquid chromatography and ultraviolet detection is described. The chromatographic conditions are optimized when an Aminex HPX-87H column (300 × 7.8 mm) is employed, with a solution of 3 mmol/L sulfuric acid as eluent, a flow rate of 0.4 mL/min and a column temperature of 60°C. Eight organic acids (including orotic acid, α-ketoglutaric acid, citric acid, pyruvic acid, malic acid, succinic acid, lactic acid and acetic acid) and one nucleotide are successfully quantified. The calibration curves for these analytes are linear, with correlation coefficients exceeding 0.999. The average recovery of organic acids is in the range of 97.6% ∼ 103.1%, and the relative standard deviation is in the range of 0.037% ∼ 0.38%. The method is subsequently applied to obtain organic acid profiles of uridine 5'-monophosphate culture broth fermented from orotic acid by Saccharomyces cerevisiae. These data demonstrate the quantitative accuracy for nucleotide fermentation mixtures, and suggest that the method may also be applicable to other biological samples.

  4. [Characteristic fingerprint analysis and determination of main components on Andrographis paniculata extract by UPLC].

    PubMed

    Zhang, Hui-ye; Xu, Xiao-fei; Huang, Yong; Wamg, De-qin; Deng, Qiao-hua

    2014-06-01

    To establish an analytical method for characteristic fingerprint and determination of main components of Andrographis paniculata Extract by UPLC. The chromatographic conditions were Waters ACQUITY UPLC BEH-C18 (2. 1 mm x 0 mm,1.7 μm)by gradient elute using acetonitrile-water as mobile phase(0 -2 min,20% ~ 25% A;2 ~ 5 min,25% ~ 35% A;5 ~ 7 min,35% A;7 ~10 min,35%~ 55% A) at a flow rate of 0. 5 min/mL,detecting wavelength at 220 nm. Results:Contents of the andrographolide, neoandrographolide, 14-deoxyandrographolide and 14-deoxy-l11,12-didehydroandrographolide had good resolution with the correlation coefficients exceed 0. 9999 and the average percent recovery lied in 97. 2% to 103.9%, RSD was less than 3.0% (n = 6). The chromatograms of Andrographis paniculata Extract shared seven common peaks in which four of them were recognized by reference standard with the similarities over 0. 9. It is a fast,accurate and validated method,and can be useful in quality evaluations of Andrographis paniculata Extract.

  5. Rapid and simple method for the determination of emodin in tartary buckwheat (Fagopyrum tataricum) by high-performance liquid chromatography coupled to a diode array detector.

    PubMed

    Peng, Lian-Xin; Wang, Jing-Bo; Hu, Li-Xue; Zhao, Jiang-Lin; Xiang, Da-Bing; Zou, Liang; Zhao, Gang

    2013-01-30

    A simple and rapid method for determining emodin, an active factor presented in tartary buckwheat (Fagopyrum tataricum), by high-performance liquid chromatography coupled to a diode array detector (HPLC-DAD) has been developed. Emodin was separated from an extract of buckwheat on a Kromasil-ODS C(18) (250 mm × 4.6 mm × 5 μm) column. The separation is achieved within 15 min on the ODS column. Emodin can be quantified using an external standard method detecting at 436 nm. Good linearity is obtained with a correlation coefficient exceeding 0.9992. The limit of detection and the limit of quantification are 5.7 and 19 μg/L, respectively. This method shows good reproducibility for the quantification of the emodin with a relative standard deviation value of 4.3%. Under optimized extraction conditions, the recovery of emodin was calculated as >90%. The validated method is successfully applied to quantify the emodin in tartary buckwheat and its products.

  6. Relationship between Organizational Perceived Justice and Organizational Citizenship Behavior among an Iranian Hospital’s Employees, 2013

    PubMed Central

    Bahrami, Mohammad Amin; Montazeralfaraj, Razieh; Gazar, Saeed Hashemi; Tafti, Arefeh Dehghani

    2014-01-01

    Background: Organizational citizenship behavior just referred to a set of discretionary workplace behaviors that exceed one’s job requirements. The main objective of this study was to determine the relationship between organizational perceived justice and organizational citizenship behavior. Methods: This cross-sectional study was done in Shahid Sadoughi Hospital in Yazd, Iran in 2013. A total of 100 hospital employees contributed in the study. The required data was gathered using 2 valid questionnaires, including the Moorman & Niehoff organizational perceived justice questionnaire and the McKinsey organizational citizenship behavior questionnaire. Data were analyzed using SPSS version 16. Descriptive statistics, Chi square, and Pearson’s correlation coefficient were used for data analysis. Results: There was a significant positive relationship between organizational perceived justice and organizational citizenship behavior among the studied hospital’s employees (P ≤ 0.05, R = 0.33). Conclusion: This study confirmed that any policy that leads to better organizational justice perception will contribute in better organizational citizenship behavior which will increase the hospital’s productivity. PMID:25763156

  7. Comparison of Polyfluoroalkyl Compound Concentrations in Maternal Serum and Amniotic Fluid: A Pilot Study

    PubMed Central

    Stein, Cheryl R.; Wolff, Mary S.; Calafat, Antonia M.; Kato, Kayoko; Engel, Stephanie M.

    2012-01-01

    The extent to which polyfluoroalkyl compounds (PFCs) are detectable in amniotic fluid is unknown. Using paired samples from 28 women, we compared the concentration of 8 PFCs measured in serum, the standard matrix for assessing human exposure, amniotic fluid from routine amniocentesis, and urine. Perfluorooctanoate (PFOA), perfluorononanoate (PFNA), perfluorooctane sulfonate (PFOS), and perfluorohexane sulfonate (PFHxS) were detected in all maternal serum samples. The number of amniotic fluid samples with detectable concentrations differed by PFC (PFOA n=24; PFNA n=10; PFOS n=9; PFHxS n=4). The correlation coefficient between maternal serum and amniotic PFC levels varied considerably by PFC (PFOA ρ=0.64, p<0.001; PFNA ρ=0.05, p=0.9; PFOS ρ=0.76, p=0.01; PFHxS ρ=0.80, p=0.2). Using linear regression, PFOA appeared to be commonly detected in amniotic fluid if the serum concentration exceeded approximately 1.5 ng/mL whereas PFOS was rarely detected in amniotic fluid until the serum concentration was about 5.5 ng/mL. No PFCs were detected in urine. PMID:22613200

  8. Income inequality, disinvestment in health care and use of dental services.

    PubMed

    Bhandari, Bishal; Newton, Jonathan T; Bernabé, Eduardo

    2015-01-01

    To explore the interrelationships between income inequality, disinvestment in health care, and use of dental services at country level. This study pooled national estimates for use of dental services among adults aged 18 years or older from the 70 countries that participated in the World Health Survey from 2002 to 2004, together with aggregate data on national income (GDP per capita), income inequality (Gini coefficient), and disinvestment in health care (total health expenditure and dentist-to-population ratio) from various international sources. Use of dental services was defined as having had dental problems in the last 12 months and having received any treatment to address those needs. Associations between variables were explored using Pearson correlation coefficients and linear regression. Data from 63 countries representing the six WHO regions were analyzed. Use of dental services was negatively correlated with Gini coefficient (Pearson correlation coefficient -0.48, P < 0.001) and positively correlated with GDP per capita (0.40, P < 0.05), total health expenditure (0.45, P < 0.001), and dentist-to-population ratio (0.67, P < 0.001). The association between Gini coefficient and use of dental services was attenuated but remained significant after adjustments for GDP per capita, total health expenditure, and dentist-to-population ratio (regression coefficient -0.36; 95% CI -0.57, -0.15). This study shows an inverse relationship between income inequality and use of dental services. Of the two indicators of disinvestment in health care assessed, only dentist-to-population ratio was associated with income inequality and use of dental services. © 2014 American Association of Public Health Dentistry.

  9. Several submaximal exercise tests are reliable, valid and acceptable in people with chronic pain, fibromyalgia or chronic fatigue: a systematic review.

    PubMed

    Ratter, Julia; Radlinger, Lorenz; Lucas, Cees

    2014-09-01

    Are submaximal and maximal exercise tests reliable, valid and acceptable in people with chronic pain, fibromyalgia and fatigue disorders? Systematic review of studies of the psychometric properties of exercise tests. People older than 18 years with chronic pain, fibromyalgia and chronic fatigue disorders. Studies of the measurement properties of tests of physical capacity in people with chronic pain, fibromyalgia or chronic fatigue disorders were included. Studies were required to report: reliability coefficients (intraclass correlation coefficient, alpha reliability coefficient, limits of agreements and Bland-Altman plots); validity coefficients (intraclass correlation coefficient, Spearman's correlation, Kendal T coefficient, Pearson's correlation); or dropout rates. Fourteen studies were eligible: none had low risk of bias, 10 had unclear risk of bias and four had high risk of bias. The included studies evaluated: Åstrand test; modified Åstrand test; Lean body mass-based Åstrand test; submaximal bicycle ergometer test following another protocol other than Åstrand test; 2-km walk test; 5-minute, 6-minute and 10-minute walk tests; shuttle walk test; and modified symptom-limited Bruce treadmill test. None of the studies assessed maximal exercise tests. Where they had been tested, reliability and validity were generally high. Dropout rates were generally acceptable. The 2-km walk test was not recommended in fibromyalgia. Moderate evidence was found for reliability, validity and acceptability of submaximal exercise tests in patients with chronic pain, fibromyalgia or chronic fatigue. There is no evidence about maximal exercise tests in patients with chronic pain, fibromyalgia and chronic fatigue. Copyright © 2014. Published by Elsevier B.V.

  10. CALIOP near-real-time backscatter products compared to EARLINET data

    NASA Astrophysics Data System (ADS)

    Grigas, T.; Hervo, M.; Gimmestad, G.; Forrister, H.; Schneider, P.; Preißler, J.; Tarrason, L.; O'Dowd, C.

    2015-03-01

    The expedited near-real-time Level 1.5 Cloud-Aerosol Lidar (Light Detection and Ranging) with Orthogonal Polarization (CALIOP) products were evaluated against data from the ground-based European Aerosol Research Lidar Network (EARLINET). Over a period of three years, lidar data from 48 CALIOP overpasses with ground tracks within a 100 km distance from an operating EARLINET station were deemed suitable for analysis and they included a valid aerosol classification type (e.g. dust, polluted dust, clean marine, clean continental, polluted continental, mixed and/or smoke/biomass burning). For the complete dataset comprising both PBL and FT data, the correlation coefficient was 0.86, and when separated into separate layers, the PBL and FT correlation coefficients were 0.6 and 0.85 respectively. The presence of FT layers with high attenuated backscatter led to poor agreement in PBL backscatter profiles between the CALIOP and EARLINET measurements and prompted a further analysis filtering out such cases. However, the correlation coefficient value for the complete dataset decreased marginally from 0.86 to 0.84 while the PBL coefficient increased from 0.6 up to 0.65 and the FT coefficient also decreased from 0.85 to 0.79. For specific aerosol types, the correlation coefficient between CALIOP backscatter profiles and ground-based lidar data ranged from 0.37 for polluted continental aerosol in the planetary boundary layer (PBL) to 0.57 for dust in the free troposphere (FT). The results suggest different levels of agreement based on the location of the dominant aerosol layer and the aerosol type.

  11. Compression of head-related transfer function using autoregressive-moving-average models and Legendre polynomials.

    PubMed

    Shekarchi, Sayedali; Hallam, John; Christensen-Dalsgaard, Jakob

    2013-11-01

    Head-related transfer functions (HRTFs) are generally large datasets, which can be an important constraint for embedded real-time applications. A method is proposed here to reduce redundancy and compress the datasets. In this method, HRTFs are first compressed by conversion into autoregressive-moving-average (ARMA) filters whose coefficients are calculated using Prony's method. Such filters are specified by a few coefficients which can generate the full head-related impulse responses (HRIRs). Next, Legendre polynomials (LPs) are used to compress the ARMA filter coefficients. LPs are derived on the sphere and form an orthonormal basis set for spherical functions. Higher-order LPs capture increasingly fine spatial details. The number of LPs needed to represent an HRTF, therefore, is indicative of its spatial complexity. The results indicate that compression ratios can exceed 98% while maintaining a spectral error of less than 4 dB in the recovered HRTFs.

  12. Required coefficient of friction during turning at self-selected slow, normal, and fast walking speeds.

    PubMed

    Fino, Peter; Lockhart, Thurmon E

    2014-04-11

    This study investigated the relationship of required coefficient of friction to gait speed, obstacle height, and turning strategy as participants walked around obstacles of various heights. Ten healthy, young adults performed 90° turns around corner pylons of four different heights at their self selected normal, slow, and fast walking speeds using both step and spin turning strategies. Kinetic data was captured using force plates. Results showed peak required coefficient of friction (RCOF) at push off increased with increased speed (slow μ=0.38, normal μ=0.45, and fast μ=0.54). Obstacle height had no effect on RCOF values. The average peak RCOF for fast turning exceeded the OSHA safety guideline for static COF of μ>0.50, suggesting further research is needed into the minimum static COF to prevent slips and falls, especially around corners. Copyright © 2014 Elsevier Ltd. All rights reserved.

  13. Quality-of-life in insect venom allergy: validation of the Turkish version of the "Vespid Allergy Quality of Life Questionnaire" (VQLQ-T).

    PubMed

    Sin, Betül Ayşe; Öztuna, Derya; Gelincik, Aslı; Gürlek, Feridun; Baysan, Abdullah; Sin, Aytül Zerrin; Aydın, Ömür; Mısırlıgil, Zeynep

    2016-01-01

    "Vespid Allergy Quality of Life Questionnaire (VQLQ)" has been used to assess psychological burden of disease. The aim of this study was to evaluate validity, reliability and responsiveness to interventions of the Turkish version. The Turkish language Questionnaire (VQLQ-T) was administered to 81 patients with bee allergy and 65 patients with vespid allergy from different groups to achieve cross-sectional validation. To establish longitudinal validity, the questionnaire was administered to 36 patients treated with venom immunotherapy. The cross-sectional validation in patients with vespid venom allergy showed a correlation coefficient of 0.97 (Cronbach α). Spearman's correlation coefficient of the pretreatment VQLQ-T score with Expectation of Outcome (EoO) questionnaire score was 0.55 (p < 0.001). After treatment, correlation between VQLQ-T score and EoO score was 0.64 (p = 0.003) in these patients. The cross-sectional instrument validation for non-beekeepers with bee venom allergy yielded a correlation coefficient of 0.96 (Cronbach α). Spearman's correlation coefficient between pretreatment VQLQ-T score and EoO score was 0.47 (p < 0.001) and after treatment, correlation between VQLQ-T score and EoO score was 0.78 (p = 0.008) in these patients. These findings indicate cross-sectional validity of VQLQ-T. In the longitudinal validation, there was a positive correlation between EoO and VQLQ-T with a correlation coefficient of 0.562 (p < 0.001). While mean (±SD) VQLQ-T score was 5.27 (±1.29) in pretreatment, it was 2.78 (±1.01) after treatment (p < 0.001). The correlation between the mean change in VQLQ-T score and the mean change in EoO score was 0.42 (p = 0.011). The Turkish version of VQLQ-T enables measurement of Quality of Life (QoL) in patients with either vespid or bee venom allergy. Furthermore, responsiveness of this instrument demonstrates the questionnaire's ability to detect changes over time.

  14. Good reliability and validity for a new utility instrument measuring the birth experience, the Labor and Delivery Index.

    PubMed

    Gärtner, Fania R; de Miranda, Esteriek; Rijnders, Marlies E; Freeman, Liv M; Middeldorp, Johanna M; Bloemenkamp, Kitty W M; Stiggelbout, Anne M; van den Akker-van Marle, M Elske

    2015-10-01

    To validate the Labor and Delivery Index (LADY-X), a new delivery-specific utility measure. In a test-retest design, women were surveyed online, 6 to 8 weeks postpartum and again 1 to 2 weeks later. For reliability testing, we assessed the standard error of measurement (S.E.M.) and the intraclass correlation coefficient (ICC). For construct validity, we tested hypotheses on the association with comparison instruments (Mackey Childbirth Satisfaction Rating Scale and Wijma Delivery Experience Questionnaire), both on domain and total score levels. We assessed known-group differences using eight obstetrical indicators: method and place of birth, induction, transfer, control over pain medication, complications concerning mother and child, and experienced control. The questionnaire was completed by 308 women, 257 (83%) completed the retest. The distribution of LADY-X scores was skewed. The reliability was good, as the ICC exceeded 0.80 and the S.E.M. was 0.76. Requirements for good construct validity were fulfilled: all hypotheses for convergent and divergent validity were confirmed, and six of eight hypotheses for known-group differences were confirmed as all differences were statistically significant (P-values: <0.001-0.023), but for two tests, difference scores did not exceed the S.E.M. The LADY-X demonstrates good reliability and construct validity. Despite its skewed distribution, the LADY-X can discriminate between groups. With the preference weights available, the LADY-X might fulfill the need for a utility measure for cost-effectiveness studies for perinatal care interventions. Copyright © 2015 Elsevier Inc. All rights reserved.

  15. Validation of an ambient measurement system (AMS) for walking speed.

    PubMed

    Varsanik, Jonathan S; Kimmel, Zebadiah M; de Moor, Carl; Gabel, Wendy; Phillips, Glenn A

    2017-07-01

    Walking speed is an important indicator of worsening in a variety of neurological and neuromuscular diseases, yet typically is measured only infrequently and in a clinical setting. Passive measurement of walking speed at home could provide valuable information to track the progression of many neuromuscular conditions. The purpose of this study was to validate the measurement of walking speed by a shelf-top ambient measurement system (AMS) that can be placed in a patient's home. Twenty-eight healthy adults (16 male, 12 female) were asked to walk three pre-defined routes two times each (total of 168 traversals). For each traversal, walking speed was measured simultaneously by five sources: two independent AMSs and three human timers with stopwatches. Measurements across the five sources were compared by generalised estimating equations (GEE). Correlation coefficients compared pairwise for walking speeds across the two AMSs, three human timers, and three routes all exceeded 0.86 (p < .0001), and for AMS-to-AMS exceeded 0.92 (p < .0001). Aggregated across all routes, there was no significant difference in measured walking speeds between the two AMSs (p = .596). There was a statistically significant difference between the AMSs and human timers of 8.5 cm/s (p < .0001), which is comparable to differences reported for other non-worn sensors. The tested AMS demonstrated the ability to automatically measure walking speeds comparable to manual observation and recording, which is the current standard for assessing walking speed in a clinical setting. The AMS may be used to detect changes in walking speed in community settings.

  16. Modeling geomagnetic induced currents in Australian power networks

    NASA Astrophysics Data System (ADS)

    Marshall, R. A.; Kelly, A.; Van Der Walt, T.; Honecker, A.; Ong, C.; Mikkelsen, D.; Spierings, A.; Ivanovich, G.; Yoshikawa, A.

    2017-07-01

    Geomagnetic induced currents (GICs) have been considered an issue for high-latitude power networks for some decades. More recently, GICs have been observed and studied in power networks located in lower latitude regions. This paper presents the results of a model aimed at predicting and understanding the impact of geomagnetic storms on power networks in Australia, with particular focus on the Queensland and Tasmanian networks. The model incorporates a "geoelectric field" determined using a plane wave magnetic field incident on a uniform conducting Earth, and the network model developed by Lehtinen and Pirjola (1985). Model results for two intense geomagnetic storms of solar cycle 24 are compared with transformer neutral monitors at three locations within the Queensland network and one location within the Tasmanian network. The model is then used to assess the impacts of the superintense geomagnetic storm of 29-31 October 2003 on the flow of GICs within these networks. The model results show good correlation with the observations with coefficients ranging from 0.73 to 0.96 across the observing sites. For Queensland, modeled GIC magnitudes during the superstorm of 29-31 October 2003 exceed 40 A with the larger GICs occurring in the south-east section of the network. Modeled GICs in Tasmania for the same storm do not exceed 30 A. The larger distance spans and general east-west alignment of the southern section of the Queensland network, in conjunction with some relatively low branch resistance values, result in larger modeled GICs despite Queensland being a lower latitude network than Tasmania.

  17. A method comparison of a food frequency questionnaire to measure folate, choline, betaine, vitamin C and carotenoids with 24-h dietary recalls in women of reproductive age.

    PubMed

    Coathup, V; Wheeler, S; Smith, L

    2016-03-01

    The objective of this study was to conduct a method comparison of a modified food frequency questionnaire (FFQ), designed to estimate usual dietary intake of selected micronutrients and antioxidants including folate, choline, betaine, vitamin C and carotenoids (α-carotene, β-carotene, lutein, lycopene and β-cryptoxanthin) with 24-h dietary recalls (24-HR) in women of reproductive age. Sixty-four British women of reproductive age (18-40 years) were recruited in Oxford, UK and provided complete dietary data for analysis. We compared micronutrient estimates from the FFQ against estimates derived from three multiple-pass, 24-HR interviews, by evaluating Pearson's correlation coefficients and Bland-Altman plots. Median intakes of most nutrients were higher when measured by FFQ compared with 24-HR. Strong correlation coefficients were observed for folate (r=0.80) and choline (r=0.68), whereas moderate correlation coefficients were observed for vitamin C (0.50) and lycopene (0.43). Weak correlation coefficients were observed for betaine (0.39) and other carotenoids (r=0.26-0.38). Bland-Altman plots indicated that there was a large amount of variability in the FFQ estimates of nutrient intakes compared to those using 24-HR, particularly for carotenoids. The findings indicate that this FFQ estimated higher mean intakes for most nutrients. Pearson's correlation coefficients were comparable with previous research; however, the Bland-Altman plots suggest a high variability in mean nutrient estimates between the FFQ and 24-h. We recommend further investigation of the validity of this FFQ before use.

  18. Detection of tissue coagulation by decorrelation of ultrasonic echo signals in cavitation-enhanced high-intensity focused ultrasound treatment.

    PubMed

    Yoshizawa, Shin; Matsuura, Keiko; Takagi, Ryo; Yamamoto, Mariko; Umemura, Shin-Ichiro

    2016-01-01

    A noninvasive technique to monitor thermal lesion formation is necessary to ensure the accuracy and safety of high-intensity focused ultrasound (HIFU) treatment. The purpose of this study is to ultrasonically detect the tissue change due to thermal coagulation in the HIFU treatment enhanced by cavitation microbubbles. An ultrasound imaging probe transmitted plane waves at a center frequency of 4.5 MHz. Ultrasonic radio-frequency (RF) echo signals during HIFU exposure at a frequency of 1.2 MHz were acquired. Cross-correlation coefficients were calculated between in-phase and quadrature (IQ) data of two B-mode images with an interval time of 50 and 500 ms for the estimation of the region of cavitation and coagulation, respectively. Pathological examination of the coagulated tissue was also performed to compare with the corresponding ultrasonically detected coagulation region. The distribution of minimum hold cross-correlation coefficient between two sets of IQ data with 50-ms intervals was compared with a pulse inversion (PI) image. The regions with low cross-correlation coefficients approximately corresponded to those with high brightness in the PI image. The regions with low cross-correlation coefficients in 500-ms intervals showed a good agreement with those with significant change in histology. The results show that the regions of coagulation and cavitation could be ultrasonically detected as those with low cross-correlation coefficients between RF frames with certain intervals. This method will contribute to improve the safety and accuracy of the HIFU treatment enhanced by cavitation microbubbles.

  19. Basic language comprehension and production in >100,000 young children from sixteen developing nations

    PubMed Central

    BORNSTEIN, MARC H.; HENDRICKS, CHARLENE

    2013-01-01

    Using the Multiple Indicator Cluster Survey, language comprehension and production were compared in a sample of 101,250 children aged 2;00 to 9;11 and a focus subsample of 38,845 children aged 2;00 to 4;11 from sixteen under-researched developing nations. In the whole sample, comprehension slightly exceeded production; correlations between comprehension and production by country were positive and significant, but varied in size, and the average correlation was positive, significant, and small to medium. Mean comprehension and production varied with child age, reaching an asymptote at 5;00, and correlations between comprehension and production by age were positive, significant, and similar at each age. In the focus subsample, comprehension exceeded production; correlations between comprehension and production by country were positive and significant, but varied in size, and the average correlation was positive, significant, and medium in size. Children in countries with lower standards of living were less likely to demonstrate basic language comprehension or production. PMID:22129486

  20. Prediction of Partition Coefficients of Organic Compounds between SPME/PDMS and Aqueous Solution

    PubMed Central

    Chao, Keh-Ping; Lu, Yu-Ting; Yang, Hsiu-Wen

    2014-01-01

    Polydimethylsiloxane (PDMS) is commonly used as the coated polymer in the solid phase microextraction (SPME) technique. In this study, the partition coefficients of organic compounds between SPME/PDMS and the aqueous solution were compiled from the literature sources. The correlation analysis for partition coefficients was conducted to interpret the effect of their physicochemical properties and descriptors on the partitioning process. The PDMS-water partition coefficients were significantly correlated to the polarizability of organic compounds (r = 0.977, p < 0.05). An empirical model, consisting of the polarizability, the molecular connectivity index, and an indicator variable, was developed to appropriately predict the partition coefficients of 61 organic compounds for the training set. The predictive ability of the empirical model was demonstrated by using it on a test set of 26 chemicals not included in the training set. The empirical model, applying the straightforward calculated molecular descriptors, for estimating the PDMS-water partition coefficient will contribute to the practical applications of the SPME technique. PMID:24534804

  1. Breeding maize as biogas substrate in Central Europe: I. Quantitative-genetic parameters for testcross performance.

    PubMed

    Grieder, Christoph; Dhillon, Baldev S; Schipprack, Wolfgang; Melchinger, Albrecht E

    2012-04-01

    Biofuels have gained importance recently and the use of maize biomass as substrate in biogas plants for production of methane has increased tremendously in Germany. The objectives of our research were to (1) estimate variance components and heritability for different traits relevant to biogas production in testcrosses (TCs) of maize, (2) study correlations among traits, and (3) discuss strategies to breed maize as a substrate for biogas fermenters. We evaluated 570 TCs of 285 diverse dent maize lines crossed with two flint single-cross testers in six environments. Data were recorded on agronomic and quality traits, including dry matter yield (DMY), methane fermentation yield (MFY), and methane yield (MY), the product of DMY and MFY, as the main target trait. Estimates of variance components showed general combining ability (GCA) to be the major source of variation. Estimates of heritability exceeded 0.67 for all traits and were even much greater in most instances. Methane yield was perfectly correlated with DMY but not with MFY, indicating that variation in MY is primarily determined by DMY. Further, DMY had a larger heritability and coefficient of genetic variation than MFY. Hence, for improving MY, selection should primarily focus on DMY rather than MFY. Further, maize breeding for biogas production may diverge from that for forage production because in the former case, quality traits seem to be of much lower importance.

  2. Space-time modeling of the photon diffusion in a three-layered model: application to the study of muscular oxygenation

    NASA Astrophysics Data System (ADS)

    Mansouri, C.; L'Huillier, J. P.; Piron, V.

    2007-07-01

    This work presents results on the modeling of the photon diffusion in a three-layered model, (skin, fat and muscle). The Finite Element method was performed in order to calculate the temporal response of the above-mentioned structure. The thickness of the fat layer was varied from 1 to 15 mm to investigate the effects of increasing fat thickness on the muscle layer absorption coefficient measurements for a source-detector spacing of 30 mm. The simulated time-resolved reflectance data, at different wavelengths, were fitted to the diffusion model to yield the scattering and absorption coefficients of muscle. The errors in estimating muscle absorption coefficients μ α depend on the thickness of the fat layer and its optical properties. In addition, it was shown that it is possible to recover with a good precision (~2.6 % of error) the absorption coefficient of muscle and this up to a thickness of the fat layer not exceeding 4mm. Beyond this limit a correction is proposed in order to make measurements coherent. The muscle-corrected absorption coefficient can be then used to calculate hemoglobin oxygenation.

  3. An asymptotic theory for cross-correlation between auto-correlated sequences and its application on neuroimaging data.

    PubMed

    Zhou, Yunyi; Tao, Chenyang; Lu, Wenlian; Feng, Jianfeng

    2018-04-20

    Functional connectivity is among the most important tools to study brain. The correlation coefficient, between time series of different brain areas, is the most popular method to quantify functional connectivity. Correlation coefficient in practical use assumes the data to be temporally independent. However, the time series data of brain can manifest significant temporal auto-correlation. A widely applicable method is proposed for correcting temporal auto-correlation. We considered two types of time series models: (1) auto-regressive-moving-average model, (2) nonlinear dynamical system model with noisy fluctuations, and derived their respective asymptotic distributions of correlation coefficient. These two types of models are most commonly used in neuroscience studies. We show the respective asymptotic distributions share a unified expression. We have verified the validity of our method, and shown our method exhibited sufficient statistical power for detecting true correlation on numerical experiments. Employing our method on real dataset yields more robust functional network and higher classification accuracy than conventional methods. Our method robustly controls the type I error while maintaining sufficient statistical power for detecting true correlation in numerical experiments, where existing methods measuring association (linear and nonlinear) fail. In this work, we proposed a widely applicable approach for correcting the effect of temporal auto-correlation on functional connectivity. Empirical results favor the use of our method in functional network analysis. Copyright © 2018. Published by Elsevier B.V.

  4. Cumulative query method for influenza surveillance using search engine data.

    PubMed

    Seo, Dong-Woo; Jo, Min-Woo; Sohn, Chang Hwan; Shin, Soo-Yong; Lee, JaeHo; Yu, Maengsoo; Kim, Won Young; Lim, Kyoung Soo; Lee, Sang-Il

    2014-12-16

    Internet search queries have become an important data source in syndromic surveillance system. However, there is currently no syndromic surveillance system using Internet search query data in South Korea. The objective of this study was to examine correlations between our cumulative query method and national influenza surveillance data. Our study was based on the local search engine, Daum (approximately 25% market share), and influenza-like illness (ILI) data from the Korea Centers for Disease Control and Prevention. A quota sampling survey was conducted with 200 participants to obtain popular queries. We divided the study period into two sets: Set 1 (the 2009/10 epidemiological year for development set 1 and 2010/11 for validation set 1) and Set 2 (2010/11 for development Set 2 and 2011/12 for validation Set 2). Pearson's correlation coefficients were calculated between the Daum data and the ILI data for the development set. We selected the combined queries for which the correlation coefficients were .7 or higher and listed them in descending order. Then, we created a cumulative query method n representing the number of cumulative combined queries in descending order of the correlation coefficient. In validation set 1, 13 cumulative query methods were applied, and 8 had higher correlation coefficients (min=.916, max=.943) than that of the highest single combined query. Further, 11 of 13 cumulative query methods had an r value of ≥.7, but 4 of 13 combined queries had an r value of ≥.7. In validation set 2, 8 of 15 cumulative query methods showed higher correlation coefficients (min=.975, max=.987) than that of the highest single combined query. All 15 cumulative query methods had an r value of ≥.7, but 6 of 15 combined queries had an r value of ≥.7. Cumulative query method showed relatively higher correlation with national influenza surveillance data than combined queries in the development and validation set.

  5. Translation, cross-cultural adaptation and validation of the Bulgarian version of the Dizziness Handicap Inventory.

    PubMed

    Georgieva-Zhostova, Spaska; Kolev, Ognyan I; Stambolieva, Katerina

    2014-09-01

    The aim of the present study was the translation, cross-cultural adaptation and validation of the Dizziness Handicap Inventory in Bulgarian language (DHI-BG). Ninety-seven vestibular patients (19 men and 78 women, mean age 45.08 ± 13.85 years) took part in the investigation. All participants were asked to fill in the DHI-BG. Internal consistency was estimated using Cronbach's alpha and item-total correlation, reproducibility by calculating Bland-Altman's limits of agreement and intraclass correlation coefficients (ICCs). Associations were estimated by Spearman's correlation coefficients. The Cronbach's alpha for the total score, functional, physical and emotional subscales of DHI-BG were 0.88, 0.75, 0.72 and 0.81. The floor and ceiling effects of the DHI-BG total scale were evaluated with respect to the limits of agreement which were ±9.4-14.53 points. Intraclass correlation coefficients (ICCs) for all scale and subscales were higher than the recommended value of 0.75 and determined good test-retest reliability. The range of items correlation for DHI-BG was from 0.27 (item 12) to 0.72 (item 3). No significant differences were observed in the Cronbach's alpha coefficients between the DHI-BG and the original version, the German and Italian versions of the questionnaire. The most significant difference was observed in comparison with the German version of DHI. Construct validity presented a moderate correlation between Romberg coefficients and DHI-BG scores and strong correlation between all scores of DHI and the self-perceived disability. The results suggest that DHI-BG scores show a good discriminative validity between groups with different levels of self-assessed disability. The Bulgarian version of the DHI is a reliable and valid tool in assessing the impact of dizziness on the quality of life in Bulgarian vestibular patients.

  6. Correlation between developmental quotients (DASII) and social quotient (Malin's VSMS) in Indian children aged 6 months to 2 years.

    PubMed

    Bhave, Anupama; Bhargava, Roli; Kumar, Rashmi

    2011-03-01

    To determine correlation between developmental quotients (DQ) (DASII) and social quotients (SQ) (Malin's Vineland Social Maturity Scale (VSMS)). Malin's VSMS and DASII were done in 135 children aged 6 months to 2 years. SQ and DQ motor and mental were correlated using Pearson's correlation coefficient (r). Mean SQ and DQ and age equivalent scores were compared. Correlation coefficients between SQ and DQ (mental and motor were 0.849 and 0.791, respectively. Social age correlated highly with mental age (r = 0.906). Mean SQ was higher than mean DQa. SQ tends to be higher than DQ and correlates best with DQ mental. © 2010 The Authors. Journal of Paediatrics and Child Health © 2010 Paediatrics and Child Health Division (Royal Australasian College of Physicians).

  7. Comparative Controller Design for a Marine Gas Turbine Propulsion Plant

    DTIC Science & Technology

    1988-09-01

    ADDRESS (City State, and ZIP Code) ,onterey, California 93943-5000 Monterey, California 93943-5000 Sa. NAME OF FUNDING/SPONSORING 8b OFFICE SYMBOL 9 ...155 7. A21 MATRIX COEFFICIENT CORRELATION DATA ----------- 156 8. A22 MATRIX COEFFICIENT CORRELATION DATA ----------- 157 9 . A23 MATRIX...Flowchart of VRD Algorithm ----------------------- 29 8. Steady State Convergence Map --------------------- 34 9 . Smoothed Dynamic Transition Map

  8. Validity and Reliability of the Turkish Version of the DSM-5 Posttraumatic Stress Symptom Severity Scale-Child Form.

    PubMed

    Yalin Sapmaz, Şermin; Ergin, Dilek; Özek Erkuran, Handan; Şen Celasin, Nesrin; Öztürk, Masum; Karaarslan, Duygu; Köroğlu, Ertuğrul; Aydemir, Ömer

    2017-09-01

    This study assessed the validity and reliability of the Turkish version of the DSM-5 Posttraumatic Stress Symptom Severity Scale-Child Form for use among the Turkish population. The study group consisted of 30 patients that had been treated in a child psychiatry unit and diagnosed with posttraumatic stress disorder and 83 healthy volunteers that were attending middle or high school during the study period. For reliability analyses, the internal consistency coefficient and the test-retest correlation coefficient were measured. For validity analyses, the exploratory factor analysis and correlation analysis with the Child Posttraumatic Stress Reaction Index for concurrent validity were measured. The Cronbach's alpha (the internal consistency coefficient) of the scale was 0.909, and the test-retest correlation coefficient was 0.663. One factor that could explain 58.5% of the variance was obtained and was congruent with the original construct of the scale. As for concurrent validity, the scale showed high correlation with the Child Posttraumatic Stress Reaction Index. It was concluded that the Turkish version of the DSM-5 Posttraumatic Stress Symptom Severity Scale-Child Form can be used as a valid and reliable tool.

  9. Fully automated, deep learning segmentation of oxygen-induced retinopathy images

    PubMed Central

    Xiao, Sa; Bucher, Felicitas; Wu, Yue; Rokem, Ariel; Lee, Cecilia S.; Marra, Kyle V.; Fallon, Regis; Diaz-Aguilar, Sophia; Aguilar, Edith; Friedlander, Martin; Lee, Aaron Y.

    2017-01-01

    Oxygen-induced retinopathy (OIR) is a widely used model to study ischemia-driven neovascularization (NV) in the retina and to serve in proof-of-concept studies in evaluating antiangiogenic drugs for ocular, as well as nonocular, diseases. The primary parameters that are analyzed in this mouse model include the percentage of retina with vaso-obliteration (VO) and NV areas. However, quantification of these two key variables comes with a great challenge due to the requirement of human experts to read the images. Human readers are costly, time-consuming, and subject to bias. Using recent advances in machine learning and computer vision, we trained deep learning neural networks using over a thousand segmentations to fully automate segmentation in OIR images. While determining the percentage area of VO, our algorithm achieved a similar range of correlation coefficients to that of expert inter-human correlation coefficients. In addition, our algorithm achieved a higher range of correlation coefficients compared with inter-expert correlation coefficients for quantification of the percentage area of neovascular tufts. In summary, we have created an open-source, fully automated pipeline for the quantification of key values of OIR images using deep learning neural networks. PMID:29263301

  10. Measurements of Heat-Transfer and Friction Coefficients for Helium Flowing in a Tube at Surface Temperatures up to 5900 Deg R

    NASA Technical Reports Server (NTRS)

    Taylor, Maynard F.; Kirchgessner, Thomas A.

    1959-01-01

    Measurements of average heat transfer and friction coefficients and local heat transfer coefficients were made with helium flowing through electrically heated smooth tubes with length-diameter ratios of 60 and 92 for the following range of conditions: Average surface temperature from 1457 to 4533 R, Reynolds numbe r from 3230 to 60,000, heat flux up to 583,200 Btu per hr per ft2 of heat transfer area, and exit Mach numbe r up to 1.0. The results indicate that, in the turbulent range of Reynolds number, good correlation of the local heat transfer coefficients is obtained when the physical properties and density of helium are evaluated at the surface temperature. The average heat transfer coefficients are best correlated on the basis that the coefficient varies with [1 + (L/D))(sup -0,7)] and that the physical properties and density are evaluated at the surface temperature. The average friction coefficients for the tests with no heat addition are in complete agreement with the Karman-Nikuradse line. The average friction coefficients for heat addition are in poor agreement with the accepted line.

  11. Adaptive Green-Kubo estimates of transport coefficients from molecular dynamics based on robust error analysis.

    PubMed

    Jones, Reese E; Mandadapu, Kranthi K

    2012-04-21

    We present a rigorous Green-Kubo methodology for calculating transport coefficients based on on-the-fly estimates of: (a) statistical stationarity of the relevant process, and (b) error in the resulting coefficient. The methodology uses time samples efficiently across an ensemble of parallel replicas to yield accurate estimates, which is particularly useful for estimating the thermal conductivity of semi-conductors near their Debye temperatures where the characteristic decay times of the heat flux correlation functions are large. Employing and extending the error analysis of Zwanzig and Ailawadi [Phys. Rev. 182, 280 (1969)] and Frenkel [in Proceedings of the International School of Physics "Enrico Fermi", Course LXXV (North-Holland Publishing Company, Amsterdam, 1980)] to the integral of correlation, we are able to provide tight theoretical bounds for the error in the estimate of the transport coefficient. To demonstrate the performance of the method, four test cases of increasing computational cost and complexity are presented: the viscosity of Ar and water, and the thermal conductivity of Si and GaN. In addition to producing accurate estimates of the transport coefficients for these materials, this work demonstrates precise agreement of the computed variances in the estimates of the correlation and the transport coefficient with the extended theory based on the assumption that fluctuations follow a Gaussian process. The proposed algorithm in conjunction with the extended theory enables the calculation of transport coefficients with the Green-Kubo method accurately and efficiently.

  12. Adaptive Green-Kubo estimates of transport coefficients from molecular dynamics based on robust error analysis

    NASA Astrophysics Data System (ADS)

    Jones, Reese E.; Mandadapu, Kranthi K.

    2012-04-01

    We present a rigorous Green-Kubo methodology for calculating transport coefficients based on on-the-fly estimates of: (a) statistical stationarity of the relevant process, and (b) error in the resulting coefficient. The methodology uses time samples efficiently across an ensemble of parallel replicas to yield accurate estimates, which is particularly useful for estimating the thermal conductivity of semi-conductors near their Debye temperatures where the characteristic decay times of the heat flux correlation functions are large. Employing and extending the error analysis of Zwanzig and Ailawadi [Phys. Rev. 182, 280 (1969)], 10.1103/PhysRev.182.280 and Frenkel [in Proceedings of the International School of Physics "Enrico Fermi", Course LXXV (North-Holland Publishing Company, Amsterdam, 1980)] to the integral of correlation, we are able to provide tight theoretical bounds for the error in the estimate of the transport coefficient. To demonstrate the performance of the method, four test cases of increasing computational cost and complexity are presented: the viscosity of Ar and water, and the thermal conductivity of Si and GaN. In addition to producing accurate estimates of the transport coefficients for these materials, this work demonstrates precise agreement of the computed variances in the estimates of the correlation and the transport coefficient with the extended theory based on the assumption that fluctuations follow a Gaussian process. The proposed algorithm in conjunction with the extended theory enables the calculation of transport coefficients with the Green-Kubo method accurately and efficiently.

  13. The relation between degree-2160 spectral models of Earth's gravitational and topographic potential: a guide on global correlation measures and their dependency on approximation effects

    NASA Astrophysics Data System (ADS)

    Hirt, Christian; Rexer, Moritz; Claessens, Sten; Rummel, Reiner

    2017-10-01

    Comparisons between high-degree models of the Earth's topographic and gravitational potential may give insight into the quality and resolution of the source data sets, provide feedback on the modelling techniques and help to better understand the gravity field composition. Degree correlations (cross-correlation coefficients) or reduction rates (quantifying the amount of topographic signal contained in the gravitational potential) are indicators used in a number of contemporary studies. However, depending on the modelling techniques and underlying levels of approximation, the correlation at high degrees may vary significantly, as do the conclusions drawn. The present paper addresses this problem by attempting to provide a guide on global correlation measures with particular emphasis on approximation effects and variants of topographic potential modelling. We investigate and discuss the impact of different effects (e.g., truncation of series expansions of the topographic potential, mass compression, ellipsoidal versus spherical approximation, ellipsoidal harmonic coefficient versus spherical harmonic coefficient (SHC) representation) on correlation measures. Our study demonstrates that the correlation coefficients are realistic only when the model's harmonic coefficients of a given degree are largely independent of the coefficients of other degrees, permitting degree-wise evaluations. This is the case, e.g., when both models are represented in terms of SHCs and spherical approximation (i.e. spherical arrangement of field-generating masses). Alternatively, a representation in ellipsoidal harmonics can be combined with ellipsoidal approximation. The usual ellipsoidal approximation level (i.e. ellipsoidal mass arrangement) is shown to bias correlation coefficients when SHCs are used. Importantly, gravity models from the International Centre for Global Earth Models (ICGEM) are inherently based on this approximation level. A transformation is presented that enables a transformation of ICGEM geopotential models from ellipsoidal to spherical approximation. The transformation is applied to generate a spherical transform of EGM2008 (sphEGM2008) that can meaningfully be correlated degree-wise with the topographic potential. We exploit this new technique and compare a number of models of topographic potential constituents (e.g., potential implied by land topography, ocean water masses) based on the Earth2014 global relief model and a mass-layer forward modelling technique with sphEGM2008. Different to previous findings, our results show very significant short-scale correlation between Earth's gravitational potential and the potential generated by Earth's land topography (correlation +0.92, and 60% of EGM2008 signals are delivered through the forward modelling). Our tests reveal that the potential generated by Earth's oceans water masses is largely unrelated to the geopotential at short scales, suggesting that altimetry-derived gravity and/or bathymetric data sets are significantly underpowered at 5 arc-min scales. We further decompose the topographic potential into the Bouguer shell and terrain correction and show that they are responsible for about 20 and 25% of EGM2008 short-scale signals, respectively. As a general conclusion, the paper shows the importance of using compatible models in topographic/gravitational potential comparisons and recommends the use of SHCs together with spherical approximation or EHCs with ellipsoidal approximation in order to avoid biases in the correlation measures.

  14. Relationship between the {sup 137}Cs whole-body counting results and soil and food contamination in farms near Chernobyl

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Takatsuji, Toshihiro; Sato, Hitoshi; Takada, Jun

    The authors measured the radioactivity in the soil and child food samples from farms near Mogilev (56--270 GBq km{sup {minus}2} {sup 137}Cs), Gomel (36--810 GBq km{sup {minus}2} {sup 137}Cs), and Klincy (59--270 GBq km{sup {minus}2} {sup 137}Cs), who had whole-body {sup 137}Cs counting results measured as part of a health examination in the Chernobyl Sasakawa Health and Medical Cooperation Project. Soil contamination on the family farm seems to be the main source of human contamination because most of the people in the area live on small farms and they and their domestic animals eat crops from the farms. A clearmore » correlation was found between the children's whole-body {sup 137}Cs counting results and the radioactivity in their food (correlation coefficient: 0.76; confidence level of correlation: 3.2 x 10{sup {minus}9}). There were also significant correlations between the whole-body {sup 137}Cs counting results and both the radioactivity of the soil samples (correlation coefficient: 0.22; confidence level of correlation: 0.0107) and the average contamination level of their current residence (correlation coefficient: 0.20; confidence level of correlation: 0.0174).« less

  15. Temporal Variability of Cumulative Risk Assessment on Phthalates in Chinese Pregnant Women: Repeated Measurement Analysis.

    PubMed

    Gao, Hui; Zhu, Bei-Bei; Tao, Xing-Yong; Zhu, Yuan-Duo; Tao, Xu-Guang; Tao, Fang-Biao

    2018-06-05

    The assessment of the combined effects of multiple phthalate exposures at low levels is a newly developed concept to avoid underestimating their actual cumulative health risk. A previous study included 3455 Chinese pregnant women. Each woman provided up to three urine samples (in total 9529). This previous study characterized the concentrations of phthalate metabolites. In the present study, the data from 9529 samples was reanalyzed to examine the cumulative risk assessment (CRA) with two models: (1) the creatinine-based and (2) the volume-based. Hazard index (HI) values for three phthalates, dibutyl phthalate, butyl benzyl phthalate, and di(2-ethylhexyl) phthalate, in the first, second, and third trimesters of pregnancy, were calculated, respectively. In creatinine-based model, 3.43%, 14.63%, and 17.28% of women showed HI based on the European Food Safety Authority tolerable daily intake exceeding 1 in the first, second, and third trimester of pregnancy, respectively. The intraclass correlation coefficient of HI was 0.49 (95% confidence interval: 0.46-0.53). Spearman correlations between HI of the creatinine model and ∑androgen disruptor (a developed potency weighted approach) ranged from 0.824 to 0.984. In summary, this study suggested a considerable risk of cumulative exposure to phthalates during the whole gestation in Chinese pregnant women. In addition, moderate temporal reproducibility indicated that single HI, estimated by the phthalate concentration in single spot of urine, seemed representative to describe the throughout pregnancy CRA. Finally, strong correlation between HI of the creatinine model and ∑androgen disruptor revealed that the creatinine-based model was more appropriate to evaluate the CRA.

  16. Indices of climate change based on patterns from CMIP5 models, and the range of projections

    NASA Astrophysics Data System (ADS)

    Watterson, I. G.

    2018-05-01

    Changes in temperature, precipitation, and other variables simulated by 40 current climate models for the 21st century are approximated as the product of the global mean warming and a spatial pattern of scaled changes. These fields of standardized change contain consistent features of simulated change, such as larger warming over land and increased high-latitude precipitation. However, they also differ across the ensemble, with standard deviations exceeding 0.2 for temperature over most continents, and 6% per degree for tropical precipitation. These variations are found to correlate, often strongly, with indices based on those of modes of interannual variability. Annular mode indices correlate, across the 40 models, with regional pressure changes and seasonal rainfall changes, particularly in South America and Europe. Equatorial ocean warming rates link to widespread anomalies, similarly to ENSO. A Pacific-Indian Dipole (PID) index representing the gradient in warming across the maritime continent is correlated with Australian rainfall with coefficient r of - 0.8. The component of equatorial warming orthogonal to this index, denoted EQN, has strong links to temperature and rainfall in Africa and the Americas. It is proposed that these indices and their associated patterns might be termed "modes of climate change". This is supported by an analysis of empirical orthogonal functions for the ensemble of standardized fields. Can such indices be used to help constrain projections? The relative similarity of the PID and EQN values of change, from models that have more skilful simulation of the present climate tropical pressure fields, provides a basis for this.

  17. Measuring family needs of people living with cancer. Portuguese validation and descriptive studies of the Family Inventory of Needs.

    PubMed

    Areia, Neide P; Major, Sofia; Relvas, Ana P

    2017-10-01

    The aim of this study was to validate the Portuguese version of the Family Inventory of Needs (FIN). The FIN aims to measure important family needs and their fulfilment by a healthcare team. This cross-sectional study involved a sample of 364 family members of cancer patients, recruited from three medical institutions and through online recruitment. Three instruments were used: a socio-demographic questionnaire, the FIN and the Brief Symptom Inventory - 18 (BSI-18). Construct validity and reliability were considered regarding the FIN's psychometric properties. The method used to determine construct validity was factor structure analysis (confirmatory factor analysis), inter-factor correlations (Spearman's rank correlation) and convergent validity (Spearman's rank correlation). To assess scale reliability, the FIN's internal consistency was evaluated (Cronbach's alpha coefficient). Descriptive and frequency statistics and tests to compare means were used to assess important needs and to what extent they were met. The four-factor structure of the FIN was confirmed. Thus, the FIN has four domains: Basic Information, Information on treatment and care, Support and Patient Comfort. Convergent validity with the BSI-18 was verified. Both subscales of the FIN and each domain exceeded the minimum reliability standard of 0.70. Family members also reported important needs that were not adequately met by healthcare professionals. The Portuguese version of the FIN seems to be a reliable and valid tool for identifying cancer patients' important family needs and to what extent these are met. Copyright © 2017 Elsevier Ltd. All rights reserved.

  18. Measures of physical activity and their correlates: the Swedish National March Cohort.

    PubMed

    Lagerros, Ylva Trolle; Bellocco, Rino; Adami, Hans-Olov; Nyrén, Olof

    2009-01-01

    We compared the results of self-estimates of physical activity obtained with a novel instrument (the Energy Expenditure Questionnaire, EEQ) to those obtained from questions typically asked in epidemiological investigations (reference method) in a cohort of 42,150 Swedish men and women, aged 18-94. In the EEQ, participants were asked to report total physical activity by estimating the total time during a typical day and night spent on different physical activity intensity levels from the lowest (corresponding to lying in bed, 0.9 Metabolic Energy Turnover; MET) to the highest, (exceeding the intensity of to shovelling snow by hand, i.e., >6 MET). As a comparison, they also estimated hours per week devoted to household chores, commuting and leisure time physical activities classified as; light, moderate and heavy. The average physical activity estimated with the EEQ was 1.36 MET or 32.6 METh/day or 2,341 kcal/day. In comparison, physical activity estimated with the reference method represented no more than 17% of this amount. The Spearman's correlation coefficient between the two measures was 0.26. Using EEQ, men reported significantly more physical activity than women (mean = 36.3 vs. 30.6 METh/day). Body mass index (BMI) > or = 25, education > or = 12 years, and age > or = 60 years were significantly associated with lower physical activity. Questions focusing on leisure time exercise and a few other selected activities provide estimates of activity that correlate poorly with self-reported total energy output from all physical activity and inactivity. Investigators need to be more explicit about which component of activity they investigate.

  19. Short-term favorable weather conditions are an important control of interannual variability in carbon and water fluxes

    DOE PAGES

    Zscheischler, Jakob; Fatichi, Simone; Wolf, Sebastian; ...

    2016-08-08

    Ecosystem models often perform poorly in reproducing interannual variability in carbon and water fluxes, resulting in considerable uncertainty when estimating the land-carbon sink. While many aggregated variables (growing season length, seasonal precipitation, or temperature) have been suggested as predictors for interannual variability in carbon fluxes, their explanatory power is limited and uncertainties remain as to their relative contributions. Recent results show that the annual count of hours where evapotranspiration (ET) is larger than its 95th percentile is strongly correlated with the annual variability of ET and gross primary production (GPP) in an ecosystem model. This suggests that the occurrence ofmore » favorable conditions has a strong influence on the annual carbon budget. Here we analyzed data from eight forest sites of the AmeriFlux network with at least 7 years of continuous measurements. We show that for ET and the carbon fluxes GPP, ecosystem respiration (RE), and net ecosystem production, counting the “most active hours/days” (i.e., hours/days when the flux exceeds a high percentile) correlates well with the respective annual sums, with correlation coefficients generally larger than 0.8. Phenological transitions have much weaker explanatory power. By exploiting the relationship between most active hours and interannual variability, we classify hours as most active or less active and largely explain interannual variability in ecosystem fluxes, particularly for GPP and RE. Our results suggest that a better understanding and modeling of the occurrence of large values in high-frequency ecosystem fluxes will result in a better understanding of interannual variability of these fluxes.« less

  20. Heat transfer and fluid mechanics measurements in transitional boundary layer flows

    NASA Technical Reports Server (NTRS)

    Wang, T.; Simon, T. W.; Buddhavarapu, J.

    1985-01-01

    Experimental results are presented to document hydrodynamic and thermal development of flat-plate boundary layers undergoing natural transition. Local heat transfer coefficients, skin friction coefficients and profiles of velocity, temperature and Reynolds normal and shear stresses are presented. A case with no transition and transitional cases with 0.68% and 2.0% free-stream disturbance intensities were investigated. The locations of transition are consistent with earlier data. A late-laminar state with significant levels of turbulence is documented. In late-transitional and early-turbulent flows, turbulent Prandtl number and conduction layer thickness values exceed, and the Reynolds analogy factor is less than, values previously measured in fully turbulent flows.

  1. FIBER AND INTEGRATED OPTICS: Investigation of a fiber-optic polarizer with a metal film and a dielectric buffer layer

    NASA Astrophysics Data System (ADS)

    Gelikonov, V. M.; Gusovskiĭ, D. D.; Konoplev, Yu N.; Leonov, V. I.; Mamaev, Yu A.; Turkin, A. A.

    1990-01-01

    A model of a plane-layer waveguide is used in a theoretical analysis of the attenuation coefficients of the TM0 and TE0 waves in a fiber-optic polarizer with a metal film and two dielectric buffer layers, one of which is the residual part of the fiber cladding. A report is given of the construction and experimental investigation of polarizers with a buffer layer of magnesium fluoride and an aluminum film operating at wavelengths of 0.63 and 0.81 μm and characterized by extinction coefficients of at least 53 and 46 dB, respectively, and by losses not exceeding 0.5 dB.

  2. Column NO2-total ozone-stratospheric temperature relationships associated with the Arctic and Antarctic ozone holes

    NASA Astrophysics Data System (ADS)

    Aheyeva, Viktoryia; Gruzdev, Aleksandr; Grishaev, Mikhail

    Data of ground-based measurements of NO2 column contents are analyzed to study winter-spring NO2 anomalies associated with negative anomalies in column ozone and stratospheric temperature. Episodes of significant decrease in column NO2 contents in the winter-spring period of 2011 in the northern hemisphere (NH) were detected at European and Siberian stations of Zvenigorod (55.7°N, Moscow Region) and Tomsk (56.5°N, West Siberia) in the middle latitudes, Harestua (60.2°N), Sodankyla (67.4°N, both in North Europe), and Zhigansk (66.8°N, East Siberia) in the high latitudes, and at the Arctic station of Scoresbysund (70.5°N, Greenland). All the stations, except Tomsk, are a part of the Network of the Detection of Atmospheric Composition Change (NDACC), and the data are accesses at http://ndacc.org. The decrease in NO2 is generally accompanied by total ozone and stratospheric temperature decrease and is shown to be caused by the transport of stratospheric air from the region of the ozone hole observed that season in the Arctic. Overpass total ozone data from Giovanni service and radiosonde data were used for the analysis. Although negative NO2 anomalies due to the transport from the Arctic were also observed in some other years, the anomalies in 2011 reached record magnitudes. A significant positive correlation has been found between variations in NO2 and ozone columns as well as NO2 column and stratospheric temperature during the winter-spring period of 2011, whereas the correlation is much weaker in years without Arctic ozone depletion. The correlation becomes even stronger if only episodes with significant NO2 decrease are considered. For example the correlation coefficients between NO2 and ozone columns deviations are about 0.9 for Zvenigorod and Scoresbysund. Correlation coefficients between variations in column NO2 and total ozone and stratospheric temperature as well as coefficients of regression of NO2 on ozone and temperature in the winter-spring period of 2011 for the Siberian stations are less than those for European stations. For comparison analysis, data of column NO2, total ozone and stratospheric temperature at the southern hemisphere (SH) stations of Dumont D’Urville (66.7°S, the Antarctic), Macquarie Island (54.5°S) and Kerguelen Island (49.3°S) (all stations are NDACC stations) were used. Correlation and regression coefficients between variations in column NO2 and total ozone as well as in column NO2 and stratospheric temperature for the winter-spring periods at the SH stations depend on the phase of the quasi-biennial oscillation (QBO) in the 30 hPa equatorial wind velocity. The correlation coefficients and the coefficients of regression of NO2 on ozone and temperature for the west QBO phase are large compared to those for the east phase. The 2011 Arctic ozone hole was observed during the west phase of the 30 hPa QBO. The calculated correlation coefficients at the NH stations for the winter-spring period of 2011 associated with the Arctic ozone hole are close to similar coefficients at the SH stations in winter-spring periods for the west QBO phase. The regression coefficients at the NH stations are less than those at the SH stations for the west QBO phase but greater than similar coefficients for the east phase. We can conclude that physico-chemical processes specific for ozone hole conditions cause spatial correlation between distribution of stratospheric NO2 and distributions of total ozone and temperature in polar and adjacent regions, which is generally stronger for stronger ozone deficit in a polar region. This results in significant time correlation between NO2, ozone and temperature at observation sites due to transport processes.

  3. Detection of moisture and moisture related phenomena from Skylab. [correlation of S-194 antenna temperature and soil moisture content measurements for Kansas and Texas

    NASA Technical Reports Server (NTRS)

    Eagleman, J. R.; Pogge, E. C.; Moore, R. K. (Principal Investigator); Hardy, N.; Lin, W.; League, L.

    1973-01-01

    The author has identified the following significant results. Correlations between the S-194 antenna temperature and soil moisture have been obtained for three sets of data; one for Skylab 2 and two for Skylab 3. The best correlations were obtained for the surface to one inch depth in two cases and for the surface to two inches for the third case. Correlation coefficients for the surface to one inch depth were -0.98, -0.95, and -0.82. The lowest correlation coefficient was obtained with total soil moisture variations less than 4% across the test site.

  4. Circulating leptin level in rheumatoid arthritis and its correlation with disease activity: a meta-analysis.

    PubMed

    Lee, Y H; Bae, S-C

    2016-12-01

    This study aimed to evaluate the relationship between the circulating serum leptin level and rheumatoid arthritis (RA) and to establish a correlation between serum leptin levels and RA activity. We searched the PUBMED, EMBASE, and Cochrane databases. A meta-analysis was performed, comparing the serum/plasma leptin levels in patients with RA and healthy controls. Correlation coefficients between serum leptin level and either disease activity score 28 (DAS28) or C‑reactive protein (CRP) in RA patients were also examined. Thirteen studies with a total of 648 RA patients and 426 controls were included in this meta-analysis. Circulating leptin level was significantly higher in the RA group than in the control group (SMD = 1.056, 95 % CI = 0.647-1.465, p = 4.2 × 10 -7 ). In addition, stratification by ethnicity showed a significantly elevated leptin level in the RA group in Caucasian, Turkish, and Arab populations (SMD = 0.813, 95 % CI = 0.137-1.490, p = 0.018, SMD = 0.981, 95 % CI = 0.307-1.655, p = 0.004, and SMD = 1.469, 95 % CI = 0.443-2.495, p = 0.005 respectively). A meta-analysis of correlation coefficients showed a small but significantly positive correlation between the circulating leptin level and either DAS28 (correlation coefficient = 0.275, 95 % CI = 0.076-0.452, p = 0.007) or CRP (correlation coefficient = 0.274, 95 % CI = 0.068-0.458, p = 0.010). Our meta-analysis demonstrated that the circulating leptin level is significantly higher in patients with RA and that a small but significantly positive correlation exists between leptin levels and RA activity.

  5. Turbulence in a gaseous hydrogen-liquid oxygen rocket combustion chamber

    NASA Technical Reports Server (NTRS)

    Lebas, J.; Tou, P.; Ohara, J.

    1975-01-01

    The intensity of turbulence and the Lagrangian correlation coefficient for a LOX-GH2 rocket combustion chamber was determined from experimental measurements of tracer gas diffusion. A combination of Taylor's turbulent diffusion theory and a numerical method for solving the conservation equations of fluid mechanics was used to calculate these quantities. Taylor's theory was extended to consider the inhomogeneity of the turbulence field in the axial direction of the combustion chamber, and an exponential function was used to represent the Lagrangian correlation coefficient. The results indicate that the value of the intensity of turbulence reaches a maximum of 14% at a location about 7" downstream from the injector. The Lagrangian correlation coefficient associated with this value is given by the above exponential expression where alpha = 10,000/sec.

  6. Correlation between mass transfer coefficient kLa and relevant operating parameters in cylindrical disposable shaken bioreactors on a bench-to-pilot scale

    PubMed Central

    2013-01-01

    Background Among disposable bioreactor systems, cylindrical orbitally shaken bioreactors show important advantages. They provide a well-defined hydrodynamic flow combined with excellent mixing and oxygen transfer for mammalian and plant cell cultivations. Since there is no known universal correlation between the volumetric mass transfer coefficient for oxygen kLa and relevant operating parameters in such bioreactor systems, the aim of this current study is to experimentally determine a universal kLa correlation. Results A Respiration Activity Monitoring System (RAMOS) was used to measure kLa values in cylindrical disposable shaken bioreactors and Buckingham’s π-Theorem was applied to define a dimensionless equation for kLa. In this way, a scale- and volume-independent kLa correlation was developed and validated in bioreactors with volumes from 2 L to 200 L. The final correlation was used to calculate cultivation parameters at different scales to allow a sufficient oxygen supply of tobacco BY-2 cell suspension cultures. Conclusion The resulting equation can be universally applied to calculate the mass transfer coefficient for any of seven relevant cultivation parameters such as the reactor diameter, the shaking frequency, the filling volume, the viscosity, the oxygen diffusion coefficient, the gravitational acceleration or the shaking diameter within an accuracy range of +/− 30%. To our knowledge, this is the first kLa correlation that has been defined and validated for the cited bioreactor system on a bench-to-pilot scale. PMID:24289110

  7. Correlation between mass transfer coefficient kLa and relevant operating parameters in cylindrical disposable shaken bioreactors on a bench-to-pilot scale.

    PubMed

    Klöckner, Wolf; Gacem, Riad; Anderlei, Tibor; Raven, Nicole; Schillberg, Stefan; Lattermann, Clemens; Büchs, Jochen

    2013-12-02

    Among disposable bioreactor systems, cylindrical orbitally shaken bioreactors show important advantages. They provide a well-defined hydrodynamic flow combined with excellent mixing and oxygen transfer for mammalian and plant cell cultivations. Since there is no known universal correlation between the volumetric mass transfer coefficient for oxygen kLa and relevant operating parameters in such bioreactor systems, the aim of this current study is to experimentally determine a universal kLa correlation. A Respiration Activity Monitoring System (RAMOS) was used to measure kLa values in cylindrical disposable shaken bioreactors and Buckingham's π-Theorem was applied to define a dimensionless equation for kLa. In this way, a scale- and volume-independent kLa correlation was developed and validated in bioreactors with volumes from 2 L to 200 L. The final correlation was used to calculate cultivation parameters at different scales to allow a sufficient oxygen supply of tobacco BY-2 cell suspension cultures. The resulting equation can be universally applied to calculate the mass transfer coefficient for any of seven relevant cultivation parameters such as the reactor diameter, the shaking frequency, the filling volume, the viscosity, the oxygen diffusion coefficient, the gravitational acceleration or the shaking diameter within an accuracy range of +/- 30%. To our knowledge, this is the first kLa correlation that has been defined and validated for the cited bioreactor system on a bench-to-pilot scale.

  8. Ridge: a computer program for calculating ridge regression estimates

    Treesearch

    Donald E. Hilt; Donald W. Seegrist

    1977-01-01

    Least-squares coefficients for multiple-regression models may be unstable when the independent variables are highly correlated. Ridge regression is a biased estimation procedure that produces stable estimates of the coefficients. Ridge regression is discussed, and a computer program for calculating the ridge coefficients is presented.

  9. Estimation of instantaneous heat transfer coefficients for a direct-injection stratified-charge rotary engine

    NASA Technical Reports Server (NTRS)

    Lee, C. M.; Addy, H. E.; Bond, T. H.; Chun, K. S.; Lu, C. Y.

    1987-01-01

    The main objective of this report was to derive equations to estimate heat transfer coefficients in both the combustion chamber and coolant pasage of a rotary engine. This was accomplished by making detailed temperature and pressure measurements in a direct-injection stratified-charge rotary engine under a range of conditions. For each sppecific measurement point, the local physical properties of the fluids were calculated. Then an empirical correlation of the coefficients was derived by using a multiple regression program. This correlation expresses the Nusselt number as a function of the Prandtl number and Reynolds number.

  10. Correlation among chronologic age, skeletal maturity, and dental age.

    PubMed

    Sukhia, Rashna H; Fida, Mubassar

    2010-01-01

    To determine the correlation among chronologic age, skeletal maturity, and dental age in reference to both sexes. In 380 subjects (147 males and 233 females) between 7 and 17 years of age, skeletal maturity was assessed using the cervical vertebral maturation stages described by Baccetti et al. Dental age was determined using the Demirjian method. The correlation between skeletal maturity and chronologic age on one side and between skeletal maturity and dental age on the other was assessed with Spearman rank correlation coefficients. Pearson correlation coefficients were used to assess the correlation between chronologic and dental age. For both sexes, significant correlations among chronologic age, skeletal maturity, and dental age were found. The mandibular first premolar had the highest correlation with skeletal maturation in both sexes. As skeletal maturity and dental age are significantly correlated, tooth development may be used to assess a patient's skeletal maturity at an early age. © 2011 BY QUINTESSENCE PUBLISHING CO, INC.

  11. Repeatability and reproducibility of corneal thickness using SOCT Copernicus HR.

    PubMed

    Vidal, Silvia; Viqueira, Valentín; Mas, David; Domenech, Begoña

    2013-05-01

    The aim of this study is to determine the reliability of corneal thickness measurements derived from SOCT Copernicus HR (Fourier domain OCT). Thirty healthy eyes of 30 subjects were evaluated. One eye of each patient was chosen randomly. Images were obtained of the central (up to 2.0 mm from the corneal apex) and paracentral (2.0 to 4.0 mm) cornea. We assessed corneal thickness (central and paracentral) and epithelium thickness. The intra-observer repeatability data were analysed using the intra-class correlation coefficient (ICC) for a range of 95 per cent within-subject standard deviation (S(W)) and the within-subject coefficient of variation (C(W)). The level of agreement by Bland-Altman analysis was also represented for the study of the reproducibility between observers and agreement between methods of measurement (automatic versus manual). The mean value of the central corneal thickness (CCT) was 542.4 ± 30.1 μm (SD). There was a high intra-observer agreement, finding the best result in the central sector with an intra-class correlation coefficient of 0.99, 95 per cent CI (0.989 to 0.997) and the worst, in the minimum corneal thickness, with an intra-class correlation coefficient of 0.672, 95 per cent CI (0.417 to 0.829). Reproducibility between observers was very high. The best result was found in the central sector thickness obtained both manually and automatically with an intra-class correlation coefficient of 0.990 in both cases and the worst result in the maximum corneal thickness with an intra-class correlation coefficient of 0.827. The agreement between measurement methods was also very high with intra-class correlation coefficient greater than 0.91. On the other hand the repeatability and reproducibility for epithelial measurements was poor. Pachymetric mapping with SOCT Copernicus HR was found to be highly repeatable and reproducible. We found that the device lacks an appropriate ergonomic design as proper focusing of the laser beam onto the cornea for anterior segment scanning required that patients were positioned slightly farther away from the machine head-rest than in the setup for retinal imaging. © 2013 The Authors. Clinical and Experimental Optometry © 2013 Optometrists Association Australia.

  12. Correlation of 3D Shift and 3D Tilt of the Patella in Patients With Recurrent Dislocation of the Patella and Healthy Volunteers: An In Vivo Analysis Based on 3-Dimensional Computer Models.

    PubMed

    Yamada, Yuzo; Toritsuka, Yukiyoshi; Nakamura, Norimasa; Horibe, Shuji; Sugamoto, Kazuomi; Yoshikawa, Hideki; Shino, Konsei

    2017-11-01

    The concepts of lateral deviation and lateral inclination of the patella, characterized as shift and tilt, have been applied in combination to evaluate patellar malalignment in patients with patellar dislocation. It is not reasonable, however, to describe the 3-dimensional (3D) positional relation between the patella and the femur according to measurements made on 2-dimensional (2D) images. The current study sought to clarify the relation between lateral deviation and inclination of the patella in patients with recurrent dislocation of the patella (RDP) by redefining them via 3D computer models as 3D shift and 3D tilt. Descriptive laboratory study. Altogether, 60 knees from 56 patients with RDP and 15 knees from 10 healthy volunteers were evaluated. 3D shift and tilt of the patella were analyzed with 3D computer models created by magnetic resonance imaging scans obtained at 10° intervals of knee flexion (0°-50°). 3D shift was defined as the spatial distance between the patellar reference point and the midsagittal plane of the femur; it is expressed as a percentage of the interepicondylar width. 3D tilt was defined as the spatial angle between the patellar reference plane and the transepicondylar axis. Correlations between the 2 parameters were assessed with the Pearson correlation coefficient. The patients' mean Pearson correlation coefficient was 0.895 ± 0.186 (range, -0.073 to 0.997; median, 0.965). In all, 56 knees (93%) had coefficients >0.7 (strong correlation); 1 knee (2%), >0.4 (moderate correlation); 2 knees (3%), >0.2 (weak correlation); and 1 knee (2%), <0.2 (no correlation). The mean correlation coefficient of the healthy volunteers was 0.645 ± 0.448 (range, -0.445 to 0.982; median, 0.834). A statistically significant difference was found in the distribution of the correlation coefficients between the patients and the healthy volunteers ( P = .0034). When distribution of the correlation coefficients obtained by the 3D analyses was compared with that by the 2D (conventional) analyses, based on the bisect offset index and patellar tilt angle, the 3D analyses showed statistically higher correlations between the lateral deviation and inclination of the patella ( P < .01). 3D shift and 3D tilt of the patella were moderately or strongly correlated in 95% of patients with RDP at 0° to 50° of knee flexion. It is not always necessary to use both parameters when evaluating patellar alignment, at least for knees with RDP at 0° to 50° of flexion. Such a description may enable surgeons to describe patellar alignment more simply, leading to a better, easier understanding of the characteristics of each patient with RDP.

  13. Training Platoon Leader Adaptive Thinking Skills in a Classroom Setting

    DTIC Science & Technology

    2011-06-01

    procedural aspects of the mission planning module, the costs involved in implementing this approach far exceed the benefits . Considerations for not using...areas covered in this class will clearly benefit 11 me). Coefficient alpha for this scale was .91. A three item scale delivered following...2006). Videogame -based training success: The impact of trainee characteristics - Year 2 (Technical Report 1188). Arlington, VA: U. S

  14. Analyzing Spatial and Temporal Variation in Precipitation Estimates in a Coupled Model

    NASA Astrophysics Data System (ADS)

    Tomkins, C. D.; Springer, E. P.; Costigan, K. R.

    2001-12-01

    Integrated modeling efforts at the Los Alamos National Laboratory aim to simulate the hydrologic cycle and study the impacts of climate variability and land use changes on water resources and ecosystem function at the regional scale. The integrated model couples three existing models independently responsible for addressing the atmospheric, land surface, and ground water components: the Regional Atmospheric Model System (RAMS), the Los Alamos Distributed Hydrologic System (LADHS), and the Finite Element and Heat Mass (FEHM). The upper Rio Grande Basin, extending 92,000 km2 over northern New Mexico and southern Colorado, serves as the test site for this model. RAMS uses nested grids to simulate meteorological variables, with the smallest grid over the Rio Grande having 5-km horizontal grid spacing. As LADHS grid spacing is 100 m, a downscaling approach is needed to estimate meteorological variables from the 5km RAMS grid for input into LADHS. This study presents daily and cumulative precipitation predictions, in the month of October for water year 1993, and an approach to compare LADHS downscaled precipitation to RAMS-simulated precipitation. The downscaling algorithm is based on kriging, using topography as a covariate to distribute the precipitation and thereby incorporating the topographical resolution achieved at the 100m-grid resolution in LADHS. The results of the downscaling are analyzed in terms of the level of variance introduced into the model, mean simulated precipitation, and the correlation between the LADHS and RAMS estimates. Previous work presented a comparison of RAMS-simulated and observed precipitation recorded at COOP and SNOTEL sites. The effects of downscaling the RAMS precipitation were evaluated using Spearman and linear correlations and by examining the variance of both populations. The study focuses on determining how the downscaling changes the distribution of precipitation compared to the RAMS estimates. Spearman correlations computed for the LADHS and RAMS cumulative precipitation reveal a disassociation over time, with R equal to 0.74 at day eight and R equal to 0.52 at day 31. Linear correlation coefficients (Pearson) returned a stronger initial correlation of 0.97, decreasing to 0.68. The standard deviations for the 2500 LADHS cells underlying each 5km RAMS cell range from 8 mm to 695 mm in the Sangre de Cristo Mountains and 2 mm to 112 mm in the San Luis Valley. Comparatively, the standard deviations of the RAMS estimates in these regions are 247 mm and 30 mm respectively. The LADHS standard deviations provide a measure of the variability introduced through the downscaling routine, which exceeds RAMS regional variability by a factor of 2 to 4. The coefficient of variation for the average LADHS grid cell values and the RAMS cell values in the Sangre de Cristo Mountains are 0.66 and 0.27, respectively, and 0.79 and 0.75 in the San Luis Valley. The coefficients of variation evidence the uniformity of the higher precipitation estimates in the mountains, especially for RAMS, and also the lower means and variability found in the valley. Additionally, Kolmogorov-Smirnov tests indicate clear spatial and temporal differences in mean simulated precipitation across the grid.

  15. Histogram analysis parameters of apparent diffusion coefficient reflect tumor cellularity and proliferation activity in head and neck squamous cell carcinoma.

    PubMed

    Surov, Alexey; Meyer, Hans Jonas; Winter, Karsten; Richter, Cindy; Hoehn, Anna-Kathrin

    2018-05-04

    Our purpose was to analyze associations between apparent diffusion coefficient (ADC) histogram analysis parameters and histopathologicalfeatures in head and neck squamous cell carcinoma (HNSCC). The study involved 32 patients with primary HNSCC. For every tumor, the following histogram analysis parameters were calculated: ADCmean, ADCmax, ADC min , ADC median , ADC mode , P10, P25, P75, P90, kurtosis, skewness, and entropy. Furthermore, proliferation index KI 67, cell count, total and average nucleic areas were estimated. Spearman's correlation coefficient (p) was used to analyze associations between investigated parameters. In overall sample, all ADC values showed moderate inverse correlations with KI 67. All ADC values except ADCmax correlated inversely with tumor cellularity. Slightly correlations were identified between total/average nucleic area and ADC mean , ADC min , ADC median , and P25. In G1/2 tumors, only ADCmode correlated well with Ki67. No statistically significant correlations between ADC parameters and cellularity were found. In G3 tumors, Ki 67 correlated with all ADC parameters except ADCmode. Cell count correlated well with all ADC parameters except ADCmax. Total nucleic area correlated inversely with ADC mean , ADC min , ADC median , P25, and P90. ADC histogram parameters reflect proliferation potential and cellularity in HNSCC. The associations between histopathology and imaging depend on tumor grading.

  16. Using beta coefficients to impute missing correlations in meta-analysis research: Reasons for caution.

    PubMed

    Roth, Philip L; Le, Huy; Oh, In-Sue; Van Iddekinge, Chad H; Bobko, Philip

    2018-06-01

    Meta-analysis has become a well-accepted method for synthesizing empirical research about a given phenomenon. Many meta-analyses focus on synthesizing correlations across primary studies, but some primary studies do not report correlations. Peterson and Brown (2005) suggested that researchers could use standardized regression weights (i.e., beta coefficients) to impute missing correlations. Indeed, their beta estimation procedures (BEPs) have been used in meta-analyses in a wide variety of fields. In this study, the authors evaluated the accuracy of BEPs in meta-analysis. We first examined how use of BEPs might affect results from a published meta-analysis. We then developed a series of Monte Carlo simulations that systematically compared the use of existing correlations (that were not missing) to data sets that incorporated BEPs (that impute missing correlations from corresponding beta coefficients). These simulations estimated ρ̄ (mean population correlation) and SDρ (true standard deviation) across a variety of meta-analytic conditions. Results from both the existing meta-analysis and the Monte Carlo simulations revealed that BEPs were associated with potentially large biases when estimating ρ̄ and even larger biases when estimating SDρ. Using only existing correlations often substantially outperformed use of BEPs and virtually never performed worse than BEPs. Overall, the authors urge a return to the standard practice of using only existing correlations in meta-analysis. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

  17. Correlation or Limits of Agreement? Applying the Bland-Altman Approach to the Comparison of Cognitive Screening Instruments.

    PubMed

    Larner, A J

    2016-01-01

    Calculation of correlation coefficients is often undertaken as a way of comparing different cognitive screening instruments (CSIs). However, test scores may correlate but not agree, and high correlation may mask lack of agreement between scores. The aim of this study was to use the methodology of Bland and Altman to calculate limits of agreement between the scores of selected CSIs and contrast the findings with Pearson's product moment correlation coefficients between the test scores of the same instruments. Datasets from three pragmatic diagnostic accuracy studies which examined the Mini-Mental State Examination (MMSE) vs. the Montreal Cognitive Assessment (MoCA), the MMSE vs. the Mini-Addenbrooke's Cognitive Examination (M-ACE), and the M-ACE vs. the MoCA were analysed to calculate correlation coefficients and limits of agreement between test scores. Although test scores were highly correlated (all >0.8), calculated limits of agreement were broad (all >10 points), and in one case, MMSE vs. M-ACE, was >15 points. Correlation is not agreement. Highly correlated test scores may conceal broad limits of agreement, consistent with the different emphases of different tests with respect to the cognitive domains examined. Routine incorporation of limits of agreement into diagnostic accuracy studies which compare different tests merits consideration, to enable clinicians to judge whether or not their agreement is close. © 2016 S. Karger AG, Basel.

  18. Detecting Pairwise Correlations in Spike Trains: An Objective Comparison of Methods and Application to the Study of Retinal Waves

    PubMed Central

    Eglen, Stephen J.

    2014-01-01

    Correlations in neuronal spike times are thought to be key to processing in many neural systems. Many measures have been proposed to summarize these correlations and of these the correlation index is widely used and is the standard in studies of spontaneous retinal activity. We show that this measure has two undesirable properties: it is unbounded above and confounded by firing rate. We list properties needed for a measure to fairly quantify and compare correlations and we propose a novel measure of correlation—the spike time tiling coefficient. This coefficient, the correlation index, and 33 other measures of correlation of spike times are blindly tested for the required properties on synthetic and experimental data. Based on this, we propose a measure (the spike time tiling coefficient) to replace the correlation index. To demonstrate the benefits of this measure, we reanalyze data from seven key studies, which previously used the correlation index to investigate the nature of spontaneous activity. We reanalyze data from β2(KO) and β2(TG) mutants, mutants lacking connexin isoforms, and also the age-dependent changes in wild-type and β2(KO) correlations. Reanalysis of the data using the proposed measure can significantly change the conclusions. It leads to better quantification of correlations and therefore better inference from the data. We hope that the proposed measure will have wide applications, and will help clarify the role of activity in retinotopic map formation. PMID:25339742

  19. Correlation of ultrasound estimated placental volume and umbilical cord blood volume in term pregnancy.

    PubMed

    Pannopnut, Papinwit; Kitporntheranunt, Maethaphan; Paritakul, Panwara; Kongsomboon, Kittipong

    2015-01-01

    To investigate the correlation between ultrasound measured placental volume and collected umbilical cord blood (UCB) volume in term pregnancy. An observational cross-sectional study of term singleton pregnant women in the labor ward at Maha Chakri Sirindhorn Medical Center was conducted. Placental thickness, height, and width were measured using two-dimensional (2D) ultrasound and calculated for placental volume using the volumetric mathematic model. After the delivery of the baby, UCB was collected and measured for its volume immediately. Then, birth weight, placental weight, and the actual placental volume were analyzed. The Pearson's correlation was used to determine the correlation between each two variables. A total of 35 pregnant women were eligible for the study. The mean and standard deviation of estimated placental volume and actual placental volume were 534±180 mL and 575±118 mL, respectively. The median UCB volume was 140 mL (range 98-220 mL). The UCB volume did not have a statistically significant correlation with the estimated placental volume (correlation coefficient 0.15; p=0.37). However, the UCB volume was significantly correlated with the actual placental volume (correlation coefficient 0.62; p<0.001) and birth weight (correlation coefficient 0.38; p=0.02). The estimated placental volume by 2D ultrasound was not significantly correlated with the UCB volume. Further studies to establish the correlation between the UCB volume and the estimated placental volume using other types of placental imaging may be needed.

  20. Cross-cultural adaptation and validation of the Turkish version of Oxford hip score.

    PubMed

    Tuğay, Baki Umut; Tuğay, Nazan; Güney, Hande; Hazar, Zeynep; Yüksel, İnci; Atilla, Bülent

    2015-06-01

    The purpose of this study was to translate the Oxford hip score (OHS) into Turkish and to evaluate the psychometric properties by testing the internal consistency, reproducibility, construct validity, and responsiveness in patients with hip osteoarthritis (OA). Oxford hip score was translated and culturally adapted according to the guidelines in the literature. Seventy patients (mean age 61.45 ± 9.29 years) with hip osteoarthritis participated in the study. Patients completed the Turkish Oxford hip score (OHS-TR), the Short-Form 36 (SF-36), and Western Ontario and McMaster Universities Index (WOMAC). Internal consistency was tested using Cronbach's α coefficient. Patients completed OHS-TR questionnaire twice in 7 days for determining the reproducibility. Correlation between the total results of both tests was determined by the Pearson correlation coefficient and intraclass correlation coefficient (ICC). Validity was assessed by calculating the Pearson correlation coefficient between the OHS-TR and WOMAC and SF-36 scores. Floor and ceiling effects were analyzed. The internal consistency was high (Cronbach's α 0.93). The construct validity showed a significant correlation between the OHS-TR and WOMAC and related SF-36 domains (p < 0.001). The ICC's ranged between 0.80 and 0.99. There was no floor or ceiling effect in total OHS-TR score. The OHS-TR questionnaire is valid, reliable, and responsive for the Turkish-speaking patients with hip OA.

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