Sample records for cost analysis division

  1. Analytical Tools for Affordability Analysis

    DTIC Science & Technology

    2015-05-01

    function (Womer)  Unit cost as a function of learning and rate  Learning with forgetting (Benkard)  Learning depreciates over time  Discretionary...Analytical Tools for Affordability Analysis David Tate Cost Analysis and Research Division Institute for Defense Analyses Report Documentation...ES) Institute for Defense Analyses, Cost Analysis and Research Division,4850 Mark Center Drive,Alexandria,VA,22311-1882 8. PERFORMING ORGANIZATION

  2. Monitoring and Controlling Engineering and Construction Management Cost Performance Within the Corps of Engineers

    DTIC Science & Technology

    1988-12-01

    COST MANAGEMENT The CMIF approach addresses total costs but does not permit the analysis of indirect costs. We found that indirect costs vary...responsibility USACE/divisions Increasing CMIF Districts/divisions level of by fund type detail G&A, technical indirect, burden Districts by fund type

  3. Ammunition Cost Research Study

    DTIC Science & Technology

    1976-06-01

    LIBRARY TECHNICAL REPORT Gerald W. Kalal Patrick J. Gannon COST ANALYSIS DIVISION (DRSAR-CPE) HEADQUARTERS, U.S. ARMY ARMAMENT COMMAND ROCK ISLAND... Kalal trick J. Gannon COST ANALYSIS DIVISION (DRSAR-CPE) HEADQUARTERS, U.S. ARMY ARMAMENT COMMAND ROCK ISLAND, ILLINOIS 61201 I UNCLASSIFIED...4. DESCRIPTIVE NOTES (Type ot report and Inclusive date») Technical Report 8- AU THOR(S> (flral name, middle Initial, laat name) Gerald W. Kalal

  4. The 1996 IDA Cost Research Symposium.

    DTIC Science & Technology

    1996-08-01

    5160 Christopher Deegan (703)602-6575 Performer: Naval Surface Warfare Center (211) Carderock Division, NSWC/CD Bethesda, Maryland 20084-5000...Moore (703) 602-0330, ext 208 Cost Engineering Research, Inc. 2011 Crystal Drive Arlington, VA 22202-3717 Bill Hugo Bob Craig Classification...Director, Force and Infrastructure Cost Analysis Division OD (PA&E) Room 2D278, The Pentagon Washington, DC 20301 Dr. Craig College LMI John Wallace

  5. 48 CFR 1552.242-70 - Indirect costs.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Protection Agency, Chief, Cost Policy and Rate Negotiation Branch (3804F), Cost Advisory and Financial Analysis Division, Washington, DC 20460. Where EPA is not the cognizant agency, the final rate proposal...

  6. 48 CFR 1552.242-70 - Indirect costs.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Protection Agency, Chief, Cost Policy and Rate Negotiation Branch (3804F), Cost Advisory and Financial Analysis Division, Washington, DC 20460. Where EPA is not the cognizant agency, the final rate proposal...

  7. Safety and cost-effectiveness analysis of laparoscopic splenectomy by secondary pedicle division using monopolar electrocautery.

    PubMed

    Zhou, Jianyin; Liu, Pingguo; Yin, Zhenyu; Zhao, Yilin; Wang, Xiaomin

    2013-09-01

    The expense of laparoscopic splenectomy (LS) has limited its use in developing countries, while medical costs are increasing worldwide. In this study, we performed LS by secondary pedicle division using monopolar electrocautery to achieve cost savings. Over seven years, we performed 45 consecutive LSs by secondary pedicle division using monopolar electrocautery (n=17) or ultrasonic shears (n=28) at a single center. These were reviewed to assess outcome and cost. Mean operating time was 179.7min, 7 conversions to open operation (15.6%) were necessary. There were four postoperative complications (8.9%) and no deaths. Twenty-three of 28 (82.1%) patients with idiopathic thrombocytopenic purpura developed a long-term positive response; and mean operative cost was RMB6,577 (US$1,034), which was much lower than that of Endo-GIATM in published reports. Between the monopolar electrocautery and ultrasonic shears groups, there were no significant differences in demographic characteristics or intraoperative and postoperative details, but operative cost was significantly lower in the former (RMB4,416, US$696 vs. RMB7,889, US$1,243; p<0.01). LS by secondary pedicle division using monopolar electrocautery is safe, efficacious and economical.

  8. Prescribed burning cost recovery analysis on nonindustrial private forestland in North Carolina

    Treesearch

    Ronald J. Myers; William Powell; Mark Megalos

    2012-01-01

    A statewide internal analysis of prescribed burning costs was conducted by the North Carolina Division of Forest Resources (NCDFR) in 2008 to examine the regional differences of site preparation and silvicultural burning costs, and to determine which components were most responsible for losses or gains. This study analyzed actual costs for 90 site preparation (2,559...

  9. An Analysis of the Cost Efficiency of the Math-Science Division Instructional Personnel at Gulf Coast Community College.

    ERIC Educational Resources Information Center

    Etheridge, Sandra Y.

    Prepared to provide a comprehensible and useable statement of the productivity of the members of the Math-Science Division at Gulf Coast Community College (GCCC), this report presents the methods and findings of a study of the income and expenditures related to each full- and part-time faculty member in the division. Following introductory…

  10. Why Don't They Just Give Us Money? Project Cost Estimating and Cost Reporting

    NASA Technical Reports Server (NTRS)

    Comstock, Douglas A.; Van Wychen, Kristin; Zimmerman, Mary Beth

    2015-01-01

    Successful projects require an integrated approach to managing cost, schedule, and risk. This is especially true for complex, multi-year projects involving multiple organizations. To explore solutions and leverage valuable lessons learned, NASA's Virtual Project Management Challenge will kick off a three-part series examining some of the challenges faced by project and program managers when it comes to managing these important elements. In this first session of the series, we will look at cost management, with an emphasis on the critical roles of cost estimating and cost reporting. By taking a proactive approach to both of these activities, project managers can better control life cycle costs, maintain stakeholder confidence, and protect other current and future projects in the organization's portfolio. Speakers will be Doug Comstock, Director of NASA's Cost Analysis Division, Kristin Van Wychen, Senior Analyst in the GAO Acquisition and Sourcing Management Team, and Mary Beth Zimmerman, Branch Chief for NASA's Portfolio Analysis Branch, Strategic Investments Division. Moderator Ramien Pierre is from NASA's Academy for Program/Project and Engineering Leadership (APPEL).

  11. Cost-effectiveness of Early Division of the Forehead Flap Pedicle.

    PubMed

    Calloway, Hollin E; Moubayed, Sami P; Most, Sam P

    2017-09-01

    The paramedian forehead flap is considered the gold standard procedure to optimally reconstruct major defects of the nose, but this procedure generally requires 2 stages, where the flap pedicle is divided 3 weeks following the initial surgery to ensure adequate revascularization of the flap from the surrounding recipient tissue bed, which can cost a patient time out of work or away from normal social habits. It has previously been shown that the pedicle may be safely divided after 2 weeks in select patients where revascularization from the recipient bed was confirmed using intraoperative laser fluorescence angiography to potentially save the patient time and money. To demonstrate the cost-effectiveness of takedown of the paramedian forehead flap pedicle after 2 weeks using angiography with indocyanine green (ICG). Retrospective cohort study of all patients who underwent 2-week division of the forehead flap after nasal reconstruction. Patient, tumor, defect, and outcomes data were collected. Cost-minimization analysis was performed by comparing the overall costs of 2-week takedown with angiography to a hypothetical patient undergoing 3-week takedown without angiography. Two-week division of the forehead flap after nasal reconstruction. Cost-minimization analysis performed by calculating the total variable costs for a patient in our cohort vs costs to a theoretical patient for whom angiography was not performed and the pedicle was divided at the 3-week mark. A total of 22 patients were included (mean [SD] age, 70.3 [10.0] years; 8 women [36.4%] and 14 men [63.6%]). The selection criteria for 2-week division of the pedicle are a wound bed with at least 50% vascularized tissue present, partial-thickness defects, and absence of nicotine use. All were divided at the 2-week mark with no instances of flap necrosis. One patient had a squamous eccrine carcinoma histology before reconstruction, all other patients had basal cell carcinoma, squamous cell carcinoma, and melanoma. Cost-minimization analysis showed that the use of angiography with ICG results in cost savings of $177 per patient on average. Two-week takedown of select paramedian forehead flap patients can be performed safely with verification using angiography with ICG. Although this technology inherently adds cost, it is cost-effective, saving a total of $177 per patient. NA.

  12. Procedures and models for estimating preconstruction costs of highway projects.

    DOT National Transportation Integrated Search

    2012-07-01

    This study presents data driven and component based PE cost prediction models by utilizing critical factors retrieved from ten years of historical project data obtained from ODOT roadway division. The study used factor analysis of covariance and corr...

  13. 7 CFR 94.5 - Charges for laboratory service.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ..., Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) COMMODITY LABORATORY TESTING PROGRAMS... costs for analysis of mandatory egg product samples at Science and Technology Division laboratories... program. The costs for any other mandatory laboratory analyses and testing of an egg product's identity...

  14. 7 CFR 94.5 - Charges for laboratory service.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ..., Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) COMMODITY LABORATORY TESTING PROGRAMS... costs for analysis of mandatory egg product samples at Science and Technology Division laboratories... program. The costs for any other mandatory laboratory analyses and testing of an egg product's identity...

  15. 7 CFR 94.5 - Charges for laboratory service.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ..., Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) COMMODITY LABORATORY TESTING PROGRAMS... costs for analysis of mandatory egg product samples at Science and Technology Division laboratories... program. The costs for any other mandatory laboratory analyses and testing of an egg product's identity...

  16. 7 CFR 94.5 - Charges for laboratory service.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ..., Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) COMMODITY LABORATORY TESTING PROGRAMS... costs for analysis of mandatory egg product samples at Science and Technology Division laboratories... program. The costs for any other mandatory laboratory analyses and testing of an egg product's identity...

  17. The Benefit-Cost Relationship in Entry Job Training in Water Distribution.

    ERIC Educational Resources Information Center

    Reames, J. P. (Jim)

    The benefit-cost relationship analysis concerns the cost effectiveness of employment and training in the Water Distribution Division of the Dallas Water Utilities Department and deals specifically with 104 entry workers hired to become pipe fitters. Half of the entry workers were enrolled in the Public Service Careers (PSC) training program and…

  18. Industrial Technology Modernization Program. Project 20. Consolidation and Automation of Material and Tool Storage. Phase 2

    DTIC Science & Technology

    1987-06-15

    GENERAL DYNAMICS FORT WORTH DIVISION INDUSTRIAL TECHNOLOGY00 N MODERNIZATION PROGRAM Phase 2 Final Project Report DT C JUNO 7 1989J1K PROJECT 20...CLASSIFICATION O THIS PAGE All other editions are obsolete. unclassified Honeywell JUNE 15, 1987 GENERAL DYNAMICS FORT WORTH DIVISION INDUSTRIAL ...SYSTEMIEQUIPMENT/MACHINING SPECIFICATIONS 33 9 VENDOR/ INDUSTRY ANALYSIS FINDING 39 10 MIS REQUIREMENTS/IMPROVEMENTS 45 11 COST BENEFIT ANALYSIS 48 12 IMPLEMENTATION

  19. An Exploratory Analysis of Differential Program Costs of Selected Occupational Curricula in Selected Illinois Junior Colleges. Final Report.

    ERIC Educational Resources Information Center

    Tomlinson, Robert M.; Rzonca, Chester S.

    This cost differential study was designed to use data collected by the Division of Vocational and Technical Education and the Illinois Junior College Board in an effort to analyze differential program costs of selected occupational curricula in six sample community colleges incurred in the fiscal year 1968-69. To be effective, a cost accounting…

  20. Food Irradiation Update and Cost Analysis

    DTIC Science & Technology

    1991-11-01

    Natick). Significant contributions were made by Dr. Irwin Taub and Mr. Christopher Rees of the Technology Acquisition Division, Food Engineering...stability. 5 Food Irradiation Update C-ost Analysis I. Introduction In the book The Physioloqy of Taste (1825), one of the pioneers of gastronomy ...review of the utility that radiation preserved foods might offer the military food service system. To date, this technology has seen limited use in the

  1. Debating Deindustrialization: A Comparative Analysis of Brazil and Mexico

    DTIC Science & Technology

    2014-09-01

    production costs and import more capital-intensive goods.29 As James Petras describes the cycle, cheap labor-intensive manufacturing decreases in...29 James Petras , “A New International Division of Labor?,” MERIP Reports, no. 94 (February 1, 1981): 28, doi:10.2307...3. Outsourcing James Petras looks at a new international division of labor and outsourcing as possible causes of manufacturing decline within an

  2. 23 CFR 635.120 - Changes and extra work.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... STD should establish and document with the Division Administrator's concurrence specific parameters as... STD shall perform and adequately document a cost analysis of each negotiated contract change or...

  3. 23 CFR 635.120 - Changes and extra work.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... STD should establish and document with the Division Administrator's concurrence specific parameters as... STD shall perform and adequately document a cost analysis of each negotiated contract change or...

  4. 23 CFR 635.120 - Changes and extra work.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... STD should establish and document with the Division Administrator's concurrence specific parameters as... STD shall perform and adequately document a cost analysis of each negotiated contract change or...

  5. 23 CFR 635.120 - Changes and extra work.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... STD should establish and document with the Division Administrator's concurrence specific parameters as... STD shall perform and adequately document a cost analysis of each negotiated contract change or...

  6. On board processing for future satellite communications systems: Comparison of FDM, TDM and hybrid accessing schemes

    NASA Technical Reports Server (NTRS)

    Berk, G.; Jean, P. N.; Rotholz, E.

    1982-01-01

    Several satellite uplink and downlink accessing schemes for customer premises service are compared. Four conceptual system designs are presented: satellite-routed frequency division multiple access (FDMA), satellite-switched time division multiple access (TDMA), processor-routed TDMA, and frequency-routed TDMA, operating in the 30/20 GHz band. The designs are compared on the basis of estimated satellite weight, system capacity, power consumption, and cost. The systems are analyzed for fixed multibeam coverage of the continental United States. Analysis shows that the system capacity is limited by the available satellite resources and by the terminal size and cost.

  7. Answering the Call for Accountability: An Activity and Cost Analysis Case Study

    ERIC Educational Resources Information Center

    Carducci, Rozana; Kisker, Carrie B.; Chang, June; Schirmer, James

    2007-01-01

    This article summarizes the findings of a case study on the creation and application of an activity-based cost accounting model that links community college salary expenditures to mission-critical practices within academic divisions of a southern California community college. Although initially applied as a financial management tool in private…

  8. 48 CFR 342.705 - Final indirect cost rates.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ...) The Division of Financial Advisory Services, NIH, shall establish indirect cost rates, fringe benefit... 48 Federal Acquisition Regulations System 4 2012-10-01 2012-10-01 false Final indirect cost rates... MANAGEMENT CONTRACT ADMINISTRATION Indirect Cost Rates 342.705 Final indirect cost rates. (a) The Division of...

  9. 48 CFR 342.705 - Final indirect cost rates.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ...) The Division of Financial Advisory Services, NIH, shall establish indirect cost rates, fringe benefit... 48 Federal Acquisition Regulations System 4 2014-10-01 2014-10-01 false Final indirect cost rates... MANAGEMENT CONTRACT ADMINISTRATION Indirect Cost Rates 342.705 Final indirect cost rates. (a) The Division of...

  10. 48 CFR 342.705 - Final indirect cost rates.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ...) The Division of Financial Advisory Services, NIH, shall establish indirect cost rates, fringe benefit... 48 Federal Acquisition Regulations System 4 2011-10-01 2011-10-01 false Final indirect cost rates... MANAGEMENT CONTRACT ADMINISTRATION Indirect Cost Rates 342.705 Final indirect cost rates. (a) The Division of...

  11. 48 CFR 342.705 - Final indirect cost rates.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ...) The Division of Financial Advisory Services, NIH, shall establish indirect cost rates, fringe benefit... 48 Federal Acquisition Regulations System 4 2013-10-01 2013-10-01 false Final indirect cost rates... MANAGEMENT CONTRACT ADMINISTRATION Indirect Cost Rates 342.705 Final indirect cost rates. (a) The Division of...

  12. 48 CFR 342.705 - Final indirect cost rates.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...) The Division of Financial Advisory Services, NIH, shall establish indirect cost rates, fringe benefit... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Final indirect cost rates... MANAGEMENT CONTRACT ADMINISTRATION Indirect Cost Rates 342.705 Final indirect cost rates. (a) The Division of...

  13. How Does the Air Force Create Effective Accountability for Initial Spares?

    DTIC Science & Technology

    1990-05-01

    effective accountability for initial spares? AUTHOR: Pamela J. Henson, Civilian, USAF The accountability for acquisition cost , schedule, and...in place to allow the Program Manager to effectively manage this cost element. Initial spares have traditionally been managed in Air Force Logistics...at Maxwell Air Force Base. Pamela became the Chief, Cost Analysis Division at HQ Air Force Logistics Command in 1987, where she received the Civilian

  14. On Proportionate and Truthful International Alliance Contributions: An Analysis of IncentiveCompatible Cost Sharing Mechanisms to Burden Sharing

    DTIC Science & Technology

    2017-03-23

    Therefore, the mecha- nism induces a stable cost sharing scheme wherein a subset of colluding players will not all benefit . In a subset of colluding...goods are not divisible and are not excludable. Cost sharing mechanisms specific to public goods have been researched extensively in the literature...Jackson & Moulin [1992] consider the sharing of cost for an indivisible public project among many players, and their work was extended by Bag [1997] to

  15. Alaska Department of Labor Administrative Services Division

    Science.gov Websites

    Sections Fiscal Research & Analysis Procurement Data Processing Budget Links State Employee Directory FY 2019 DOLWD Budget (Proposed) FY 2018 DOLWD Budget (Enacted) FY 2018 Indirect Cost Proposal FY 2016

  16. A Cost Benefit - Analysis of Establishing a Warehouse Facility for the Services Division of the Directorate of Personnel and Community Activities at Fort Ord, California

    DTIC Science & Technology

    1990-06-01

    Thomas J. Strel Approved by: , . ,, William R. Gates, Thesis Advisor Paul M. Carrick, Second Reader y David R. Wh pl e , Chairman Department of...AFFAIRS DEPARTM ENT .................................. 2 B. CURRENT PROCUREMENT PROCEDURES ................. 4 C. REASONS TO CHANGE CURRENT PRACTICES...Storage, Handling and Distribution Requirements and Cost . 32 e . Inventory - Ordering and Holding Costs and Order Quantity

  17. Proceedings of the FAA Inspection Program Area Review, Held in Ames, Iowa on April 5-7, 1994

    DTIC Science & Technology

    1994-07-01

    Colin Drury Mr. Locke Easton SUNY Buffalo ANE-1 00, Aircraft Certification Division, Engine and 342 Bell Mall Propeller Directorate Buffalo, NY 14260...and Tech Transfer Walter Validation: 13:10 MOI validation F. Spencer, SNL 13:30 Cost Benefit Analysis Protocol (with MOI example) V. Brechling, NWU 13...on the need for calibration of the instrument were briefly addressed. Cost -Benefit Analysis: ATA members took unexpected interest in the presentation

  18. Evolutionary dynamics of division of labor games with selfish agents

    NASA Astrophysics Data System (ADS)

    Zhang, Jianlei; Li, Qiaoyu; Zhang, Chunyan

    2017-11-01

    The division of labor is one of the most basic and widely studied aspects of collective behavior in natural systems. Studies of division of labor are concerned with the integration of the individual worker behavior into a colony level task organization and with the question of how the regulation of the division of labor may contribute to the colony efficiency. This paper investigates the evolution of the division of labor with three strategies by employing the evolutionary game theory. Thus, these available strategies are, respectively, strategy A (performing task A), strategy B (performing task B), and strategy D (not performing any task but only free riding others' contributions). And, two typical networks (i.e., BA scale-free network and lattice network) are employed here for describing the interaction structure among agents. The theoretical analysis together with simulation results reveal that the division of labor can evolve and leads to players that differ in their tendency to take on a given task. The conditions under which the division of labor evolves depend on the costs for performing the task, the benefits led by performing the task, and the interaction structures among the players who are involved with division of labor games.

  19. Task-switching costs promote the evolution of division of labor and shifts in individuality

    PubMed Central

    Goldsby, Heather J.; Dornhaus, Anna; Kerr, Benjamin; Ofria, Charles

    2012-01-01

    From microbes to humans, the success of many organisms is achieved by dividing tasks among specialized group members. The evolution of such division of labor strategies is an important aspect of the major transitions in evolution. As such, identifying specific evolutionary pressures that give rise to group-level division of labor has become a topic of major interest among biologists. To overcome the challenges associated with studying this topic in natural systems, we use actively evolving populations of digital organisms, which provide a unique perspective on the de novo evolution of division of labor in an open-ended system. We provide experimental results that address a fundamental question regarding these selective pressures: Does the ability to improve group efficiency through the reduction of task-switching costs promote the evolution of division of labor? Our results demonstrate that as task-switching costs rise, groups increasingly evolve division of labor strategies. We analyze the mechanisms by which organisms coordinate their roles and discover strategies with striking biological parallels, including communication, spatial patterning, and task-partitioning behaviors. In many cases, under high task-switching costs, individuals cease to be able to perform tasks in isolation, instead requiring the context of other group members. The simultaneous loss of functionality at a lower level and emergence of new functionality at a higher level indicates that task-switching costs may drive both the evolution of division of labor and also the loss of lower-level autonomy, which are both key components of major transitions in evolution. PMID:22872867

  20. Expanding the Role of Maryland Community Colleges in K-12 Teacher Preparation: Benefits and Costs of Implementing the Associate of Arts in Teaching (AAT) Degree

    ERIC Educational Resources Information Center

    Frank, Jennifer Vest

    2012-01-01

    This study uses benefit-cost analysis to compare three alternative scenarios for implementing the Associate of Arts in Teaching (AAT) degree in Maryland community colleges. The first policy scenario is that community colleges retain their traditional role in K-12 teacher preparation by providing lower-division transfer courses and programs for…

  1. U.S. Army Chemical Corps Historical Studies, Gas Warfare in World War I: The 5th Division Captures Frapelle, August 1918

    DTIC Science & Technology

    1958-03-01

    U. S . ARMY CHEMICAL CORPS HISTORICAL STUDIES GAS WARFARE IN WORLD WAR I THE 5t1h DIVISION CAPTURES FRAPELLF, 00 August 1918 CTD Offce t e Chef Ch mal...j JNSPECrrr / D~iJ f ; t t] GA o WARFARE IN WORLD WAR I By - --------- St ixdy Number 7 t:a . • ’ I : : . .. s U.S. ARMY CHEIICAL CORPS [ist...Analysi s Concerning the Weight of Shell . . . . . . . ... . 38 The Cost of Frapelle . . . . . . . . . . . .. 41 Medical Department Comments

  2. How to take deontological concerns seriously in risk-cost-benefit analysis: a re-interpretation of the precautionary principle.

    PubMed

    John, S D

    2007-04-01

    In this paper the coherence of the precautionary principle as a guide to public health policy is considered. Two conditions that any account of the principle must meet are outlined, a condition of practicality and a condition of publicity. The principle is interpreted in terms of a tripartite division of the outcomes of action (good outcomes, normal bad outcomes and special bad outcomes). Such a division of outcomes can be justified on either "consequentialist" or "deontological" grounds. In the second half of the paper, it is argued that the precautionary principle is not necessarily opposed to risk-cost-benefit analysis, but, rather, should be interpreted as suggesting a lowering of our epistemic standards for assessing evidence that there is a link between some policy and "special bad" outcomes. This suggestion is defended against the claim that it mistakes the nature of statistical testing and against the charge that it is unscientific or antiscientific, and therefore irrational.

  3. Cost Analysis of an Air Brayton Receiver for a Solar Thermal Electric Power System in Selected Annual Production Volumes

    NASA Technical Reports Server (NTRS)

    1981-01-01

    Pioneer Engineering and Manufacturing Company estimated the cost of manufacturing and Air Brayton Receiver for a Solar Thermal Electric Power System as designed by the AiResearch Division of the Garrett Corporation. Production costs were estimated at annual volumes of 100; 1,000; 5,000; 10,000; 50,000; 100,000 and 1,000,000 units. These costs included direct labor, direct material and manufacturing burden. A make or buy analysis was made of each part of each volume. At high volumes special fabrication concepts were used to reduce operation cycle times. All costs were estimated at an assumed 100% plant capacity. Economic feasibility determined the level of production at which special concepts were to be introduced. Estimated costs were based on the economics of the last half of 1980. Tooling and capital equipment costs were estimated for ach volume. Infrastructure and personnel requirements were also estimated.

  4. The Costs of Frontloading.

    ERIC Educational Resources Information Center

    Brinkman, Paul T.; Jones, Dennis P.

    The costs of directing additional instructional resources to lower-division instruction is assessed. "Frontloading," or directing additional resources toward lower-division students, was recommended by a national study group because first- and second-year students are frequently taught by junior instructors in large classes in which they…

  5. [Cost analysis of treatment for severe rheumatoid arthritis in a city in southern Brazil].

    PubMed

    Buendgens, Fabíola Bagatini; Blatt, Carine Raquel; Marasciulo, Antônio Carlos Estima; Leite, Silvana Nair; Farias, Mareni Rocha

    2013-11-01

    Treatment of rheumatoid arthritis involves the use of medicines, non-pharmaceutical therapies, medical appointments, and complimentary tests, among other procedures. Based on sources of payment, this article presents the direct medical costs related to treatment of rheumatoid arthritis. The cost analysis included 103 patients with severe rheumatoid arthritis treated at the Specialized Division of Pharmaceutical Care in Florianopolis, Santa Catarina State, Brazil. Total annual direct cost was R$ 2,045,596.55 (approximately one million US dollars), or R$ 19,860.16 per patient/year (slightly less than ten thousand US dollars). Total cost breakdown was as follows: 90.8% for medicines, 2.5% for hospitalizations, 2.2% for complimentary tests, 2.1% for medical appointments, and 2.4% for all other costs. The public sector accounted for 73.6% of the total direct medical costs and 79.3% of the cost of medicines. The cost analysis provided a profile of how a group of individuals with a chronic non-communicable disease that requires resources circulates in the public-private mix that characterizes the Brazilian health system.

  6. The Economic Costs of Reserve Forces Utilization: An Analysis of Their Employment in Fighting the Global War on Terrorism

    DTIC Science & Technology

    2007-12-01

    significantly affecting American society. Part of the cost is associated with the employment of the Reserve Forces, who are often subject to multiple ...he’s been able to quantify that comprise the total cost of the war in Iraq over a decade-long time frame ranging from 2003- 2012 . Such a methodology...configurations.”70 It’s genesis flowed in the Army’s desire to raise the number of total active divisions without a change in active duty personnel

  7. Business Case Analysis of Prototype Fabrication Division Recapitalization Plan. Summary

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Booth, Steven Richard; Benson, Faith Ann; Dinehart, Timothy Grant

    Business case studies were completed to support procurement of new machines and capital equipment in the Prototype Fabrication (PF) Division SM-39 and TA-03-0102 machine shops. Economic analysis was conducted for replacing the Mazak 30Y Mill-Turn Machine in SM-39, the Haas Vertical CNC Mill in Building 102, and the Hardinge Q10/65-SP Lathe in SM-39. Analysis was also conducted for adding a NanoTech Lathe in Building 102 and a new electrical discharge machine (EDM) in SM-39 to augment current capabilities. To determine the value of switching machinery, a baseline scenario was compared with a future scenario where new machinery was purchased andmore » installed. Costs and benefits were defined via interviews with subject matter experts.« less

  8. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Green, D.W.; Heinrich, R.R.; Jensen, K.J.

    Technical and administrative activities of the Analytical Chemistry Laboratory (ACL) are reported for fiscal year 1984. The ACL is a full-cost-recovery service center, with the primary mission of providing a broad range of technical support services to the scientific and engineering programs at ANL. In addition, ACL conducts a research program in analytical chemistry, works on instrumental and methods development, and provides analytical services for governmental, educational, and industrial organizations. The ACL is administratively within the Chemical Technology Division, the principal user, but provides technical support for all of the technical divisions and programs at ANL. The ACL has threemore » technical groups - Chemical Analysis, Instrumental Analysis, and Organic Analysis. Under technical activities 26 projects are briefly described. Under professional activities, a list is presented for publications and reports, oral presentations, awards and meetings attended. 6 figs., 2 tabs.« less

  9. 78 FR 59718 - Notice of Lodging of Proposed Settlement Agreement Under the Comprehensive Environmental Response...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-27

    ... response costs, natural resource damages, and natural resource damage assessment costs pursuant to Section... the Assistant Attorney General, Environment and Natural Resources Division, and should refer to In re... Enforcement Section, Environment and Natural Resources Division. [FR Doc. 2013-23500 Filed 9-26-13; 8:45 am...

  10. An Update on Physician Practice Cost Shares

    PubMed Central

    Dayhoff, Debra A.; Cromwell, Jerry; Rosenbach, Margo L.

    1993-01-01

    The 1988 physicians' practice costs and income survey (PPCIS) collected detailed costs, revenues, and incomes data for a sample of 3,086 physicians. These data are utilized to update the Health Care Financing Administration (HCFA) cost shares used in calculating the medicare economic index (MEI) and the geographic practice cost index (GPCI). Cost shares were calculated for the national sample, for 16 specialty groupings, for urban and rural areas, and for 9 census divisions. Although statistical tests reveal that cost shares differ across specialties and geographic areas, sensitivity analysis shows that these differences are small enough to have trivial effects in computing the MEI and GPCI. These results may inform policymakers on one aspect of the larger issue of whether physician payments should vary by geographic location or specialty. PMID:10130573

  11. Large-scale use of mosquito larval source management for malaria control in Africa: a cost analysis.

    PubMed

    Worrall, Eve; Fillinger, Ulrike

    2011-11-08

    At present, large-scale use of two malaria vector control methods, long-lasting insecticidal nets (LLINs) and indoor residual spraying (IRS) is being scaled up in Africa with substantial funding from donors. A third vector control method, larval source management (LSM), has been historically very successful and is today widely used for mosquito control globally, except in Africa. With increasing risk of insecticide resistance and a shift to more exophilic vectors, LSM is now under re-evaluation for use against afro-tropical vector species. Here the costs of this intervention were evaluated. The 'ingredients approach' was used to estimate the economic and financial costs per person protected per year (pppy) for large-scale LSM using microbial larvicides in three ecologically diverse settings: (1) the coastal metropolitan area of Dar es Salaam in Tanzania, (2) a highly populated Kenyan highland area (Vihiga District), and (3) a lakeside setting in rural western Kenya (Mbita Division). Two scenarios were examined to investigate the cost implications of using alternative product formulations. Sensitivity analyses on product prices were carried out. The results show that for programmes using the same granular formulation larviciding costs the least pppy in Dar es Salaam (US$0.94), approximately 60% more in Vihiga District (US$1.50) and the most in Mbita Division (US$2.50). However, these costs are reduced substantially if an alternative water-dispensable formulation is used; in Vihiga, this would reduce costs to US$0.79 and, in Mbita Division, to US$1.94. Larvicide and staff salary costs each accounted for approximately a third of the total economic costs per year. The cost pppy depends mainly on: (1) the type of formulation required for treating different aquatic habitats, (2) the human population density relative to the density of aquatic habitats and (3) the potential to target the intervention in space and/or time. Costs for LSM compare favourably with costs for IRS and LLINs, especially in areas with moderate and focal malaria transmission where mosquito larval habitats are accessible and well defined. LSM presents an attractive tool to be integrated in ongoing malaria control effort in such settings. Further data on the epidemiological health impact of larviciding is required to establish cost effectiveness.

  12. Large-scale use of mosquito larval source management for malaria control in Africa: a cost analysis

    PubMed Central

    2011-01-01

    Background At present, large-scale use of two malaria vector control methods, long-lasting insecticidal nets (LLINs) and indoor residual spraying (IRS) is being scaled up in Africa with substantial funding from donors. A third vector control method, larval source management (LSM), has been historically very successful and is today widely used for mosquito control globally, except in Africa. With increasing risk of insecticide resistance and a shift to more exophilic vectors, LSM is now under re-evaluation for use against afro-tropical vector species. Here the costs of this intervention were evaluated. Methods The 'ingredients approach' was used to estimate the economic and financial costs per person protected per year (pppy) for large-scale LSM using microbial larvicides in three ecologically diverse settings: (1) the coastal metropolitan area of Dar es Salaam in Tanzania, (2) a highly populated Kenyan highland area (Vihiga District), and (3) a lakeside setting in rural western Kenya (Mbita Division). Two scenarios were examined to investigate the cost implications of using alternative product formulations. Sensitivity analyses on product prices were carried out. Results The results show that for programmes using the same granular formulation larviciding costs the least pppy in Dar es Salaam (US$0.94), approximately 60% more in Vihiga District (US$1.50) and the most in Mbita Division (US$2.50). However, these costs are reduced substantially if an alternative water-dispensable formulation is used; in Vihiga, this would reduce costs to US$0.79 and, in Mbita Division, to US$1.94. Larvicide and staff salary costs each accounted for approximately a third of the total economic costs per year. The cost pppy depends mainly on: (1) the type of formulation required for treating different aquatic habitats, (2) the human population density relative to the density of aquatic habitats and (3) the potential to target the intervention in space and/or time. Conclusion Costs for LSM compare favourably with costs for IRS and LLINs, especially in areas with moderate and focal malaria transmission where mosquito larval habitats are accessible and well defined. LSM presents an attractive tool to be integrated in ongoing malaria control effort in such settings. Further data on the epidemiological health impact of larviciding is required to establish cost effectiveness. PMID:22067606

  13. Model for Evaluating the Cost Consequences of Deferring New System Acquisition Through Upgrades

    DTIC Science & Technology

    1999-07-01

    Analysis & Evaluation The Pentagon Washington, DC 20301 Attn: Mr. Eric Coulter, Director Projection Forces Division, Room 2E314 Lt Col Kathleen Conley...1034 Office of the Air National Guard ANG/AQM 5109 Leesburg Pike Skyline VI, Suite 302A Falls Church, VA 22041-3201 Attn: Col Brent Marler 1 Lt Col

  14. Mid-Latitude Mobile Wideband HF- NVIS Channel Analysis: Part 1

    DTIC Science & Technology

    2017-09-14

    Division EXECUTIVE SUMMARY High frequency (HF) links (2 to 30 MHz) are an alternative to the cost and tactical fragility of commercial satellite...43 4.5 HIGH -LATITUDE HF AND HF-NVIS MODELS...ionosphere without vehicle speed..................... B-6 xi 1. REPORT OUTLINE This report analyzes a mid-latitude wideband high frequency nearly vertical

  15. An Analysis of the Navy’s Fiscal Year 2017 Shipbuilding Plan

    DTIC Science & Technology

    2017-02-01

    Navy would build a larger fleet of about 350 ships (see Table 5). Those three alternatives were chosen for illustrative purposes because variations ...3.2 billion. 2. For more on procedures for estimating and applying learning curves, see Matthew S. Goldberg and Anduin E. Touw, Statistical Methods...guidance from Matthew Goldberg (formerly of CBO) and David Mosher. Raymond Hall of CBO’s Budget Analysis Division produced the cost estimates with

  16. Working time use and division of labour among nurses and health-care workers in hospitals - a systematic review.

    PubMed

    Lavander, Päivi; Meriläinen, Merja; Turkki, Leena

    2016-11-01

    This systematic review aimed to synthesise the existing evidence of working time use and the division of labour among nurses and health-care workers in hospital wards. The environment of nursing work is changing. Health systems are becoming more complex and costly, and highly skilled health-care professionals are transferring to new, more demanding tasks. Changes require a division of labour that is based on the efficient use of working time. Sixteen studies were identified for the final analysis through a systematic search. The use of working time was examined mainly through six categories: direct care, indirect care, documentation, unit-related work, personal time and non-nursing duties. The division of labour was examined from the perspective of different occupational groups. Despite nurses' different educational backgrounds, certain similarities could be observed. All working groups seem to spend less than half of their working time in direct patient care. Nurse managers could influence the increasing nursing workload by supporting the right division of labour and focusing the nurses' working time use so that it benefits the patient. © 2016 John Wiley & Sons Ltd.

  17. The Technical Problems of Anti-theft Diagnostics in a Traction Network

    NASA Astrophysics Data System (ADS)

    Mikulski, Jerzy; Młynczak, Jakub

    2012-02-01

    The paper presents an analysis of traction lines theft in the Katowice division of the Railroad Development Company (Zakład Linii Kolejowych - ZLK) as well as the principles for the anti-theft protection system, currently in development. The problem of theft is a very important issue concerning the safety of rail transportation. It is also a significant economic problem, as the cost of recreating a stolen network is very high. Moreover, the Administrator of the infrastructure bears the cost of compensation for any delays in train schedules.

  18. Space biology initiative program definition review. Trade study 5: Modification of existing hardware (COTS) versus new hardware build cost analysis

    NASA Technical Reports Server (NTRS)

    Jackson, L. Neal; Crenshaw, John, Sr.; Davidson, William L.; Blacknall, Carolyn; Bilodeau, James W.; Stoval, J. Michael; Sutton, Terry

    1989-01-01

    The JSC Life Sciences Project Division has been directly supporting NASA Headquarters, Life Sciences Division, in the preparation of data from JSC and ARC to assist in defining the Space Biology Initiative (SBI). GE Government Services and Horizon Aerospace have provided contract support for the development and integration of review data, reports, presentations, and detailed supporting data. An SBI Definition (Non-Advocate) Review at NASA Headquarters, Code B, has been scheduled for the June-July 1989 time period. In a previous NASA Headquarters review, NASA determined that additional supporting data would be beneficial to determine the potential advantages in modifying commercial off-the-shelf (COTS) hardware for some SBI hardware items. In order to meet the demands of program implementation planning with the definition review in late spring of 1989, the definition trade study analysis must be adjusted in scope and schedule to be complete for the SBI Definition (Non-Advocate) Review. The relative costs of modifying existing commercial off-the-shelf (COTS) hardware is compared to fabricating new hardware. An historical basis for new build versus modifying COTS to meet current NMI specifications for manned space flight hardware is surveyed and identified. Selected SBI hardware are identified as potential candidates for off-the-shelf modification and statistical estimates on the relative cost of modifying COTS versus new build are provided.

  19. Further Evidence on the Effect of Acquisition Policy and Process on Cost Growth

    DTIC Science & Technology

    2016-04-30

    bust periods. A complete summary also would need to take into account parallel analyses for the boom periods and the comparisons of cost growth in...qÜáêíÉÉåíÜ=^ååì~ä= ^Åèìáëáíáçå=oÉëÉ~êÅÜ= póãéçëáìã= tÉÇåÉëÇ~ó=pÉëëáçåë= sçäìãÉ=f= = Further Evidence on the Effect of Acquisition Policy and Process on Cost ...Goeller, Defense Acquisition Analyst, Institute for Defense Analyses Stanley Horowitz, Assistant Director, Cost Analysis and Research Division

  20. An Analysis of the Navy’s Fiscal Year 2012 Shipbuilding Plan

    DTIC Science & Technology

    2011-06-01

    Documentation Page Form ApprovedOMB No. 0704-0188 Public reporting burden for the collection of information is estimated to average 1 hour per response...penalty for failing to comply with a collection of information if it does not display a currently valid OMB control number. 1 . REPORT DATE JUN 2011 2...Raymond Hall of CBO’s Budget Analysis Division produced the cost estimates under the general supervision of Sarah Jennings . Bernard Kempinski

  1. Government conceptual estimating for contracting and management

    NASA Technical Reports Server (NTRS)

    Brown, J. A.

    1986-01-01

    The use of the Aerospace Price Book, a cost index, and conceptual cost estimating for cost-effective design and construction of space facilities is discussed. The price book consists of over 200 commonly used conceptual elements and 100 systems summaries of projects such as launch pads, processing facilities, and air locks. The cost index is composed of three divisions: (1) bid summaries of major Shuttle projects, (2) budget cost data sheets, and (3) cost management summaries; each of these divisions is described. Conceptual estimates of facilities and ground support equipment are required to provide the most probable project cost for budget, funding, and project approval purposes. Similar buildings, systems, and elements already designed are located in the cost index in order to make the best rough order of magnitude conceptual estimates for development of Space Shuttle facilities. An example displaying the applicability of the conceptual cost estimating procedure for the development of the KSC facilities is presented.

  2. The Effect of Automation on Job Duties, Classifications, Staffing Patterns, and Labor Costs in the UBC Library's Cataloguing Divisions: A Comparison of 1973 and 1986.

    ERIC Educational Resources Information Center

    de Bruijn, Erik

    This report discusses an ex post facto study that was done to examine the effect that the implementation of automated systems has had on libraries and support staff, labor costs, and productivity in the cataloging divisions of the library of the University of British Columbia. A comparison was made between two years: 1973, a pre-automated period…

  3. Economic Analysis of the South Pole Traverse

    DTIC Science & Technology

    2014-05-29

    unlimited. Prepared for National Science Foundation , Division of Polar Programs, Antarctic Infrastructure and Logistics Arlington, VA 22230 Under...with those by LC130 airlift ...................... 20 ERDC/CRREL TR-14-7 vii Preface This study was conducted for the National Science Foundation (NSF...historic bulk-fuel costs. Arlington, VA: National Science Foundation . Firebirds. 2012. From Schenectady to the Poles. The 109th Airlift Wing, New York

  4. A Policy Assessment of Priorities and Functional Needs for the Military Computer-Assisted Instruction Terminal

    DTIC Science & Technology

    1975-12-01

    ceases to act as a testing ground for determining user needs when demand is low relative to high initial development costs. Customers are forced to...ANASTASIO Associate Director Data Analysis Research Division Educational Testing Service Princeton, NJ 08540 (609)921-9000 Director of Educational...technology and educational psychology - Indiana University. Research interestes in adaptive, interactive instructional systems. Management

  5. Data Optical Networking Architecture Using Wavelength-Division Multiplexing Method for Optical Sensors

    NASA Technical Reports Server (NTRS)

    Nguyen, Hung D.

    2008-01-01

    Recently there has been a growth in the number of fiber optical sensors used for health monitoring in the hostile environment of commercial aircraft. Health monitoring to detect the onset of failure in structural systems from such causes as corrosion, stress corrosion cracking, and fatigue is a critical factor in safety as well in aircraft maintenance costs. This report presents an assessment of an analysis model of optical data networking architectures used for monitoring data signals among these optical sensors. Our model is focused on the design concept of the wavelength-division multiplexing (WDM) method since most of the optical sensors deployed in the aircraft for health monitoring typically operate in a wide spectrum of optical wavelengths from 710 to 1550 nm.

  6. Mathematical supply-chain modelling: Product analysis of cost and time

    NASA Astrophysics Data System (ADS)

    Easters, D. J.

    2014-03-01

    Establishing a mathematical supply-chain model is a proposition that has received attention due to its inherent benefits of evolving global supply-chain efficiencies. This paper discusses the prevailing relationships found within apparel supply-chain environments, and contemplates the complex issues indicated for constituting a mathematical model. Principal results identified within the data suggest, that the multifarious nature of global supply-chain activities require a degree of simplification in order to fully dilate the necessary factors which affect, each sub-section of the chain. Subsequently, the research findings allowed the division of supply-chain components into sub-sections, which amassed a coherent method of product development activity. Concurrently, the supply-chain model was found to allow systematic mathematical formulae analysis, of cost and time, within the multiple contexts of each subsection encountered. The paper indicates the supply-chain model structure, the mathematics, and considers how product analysis of cost and time can improve the comprehension of product lifecycle management.

  7. Heating, Ventilation, and Air Conditioning Design Strategy for a Hot-Humid Production Builder

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kerrigan, P.

    2014-03-01

    Building Science Corporation (BSC) worked directly with the David Weekley Homes - Houston division to develop a cost-effective design for moving the HVAC system into conditioned space. In addition, BSC conducted energy analysis to calculate the most economical strategy for increasing the energy performance of future production houses in preparation for the upcoming code changes in 2015. This research project addressed the following questions: 1. What is the most cost effective, best performing and most easily replicable method of locating ducts inside conditioned space for a hot-humid production home builder that constructs one and two story single family detached residences?more » 2. What is a cost effective and practical method of achieving 50% source energy savings vs. the 2006 International Energy Conservation Code for a hot-humid production builder? 3. How accurate are the pre-construction whole house cost estimates compared to confirmed post construction actual cost?« less

  8. IFLA General Conference, 1989. Division of Bibliographic Control. Open Forum of the Division; Section on Cataloguing; Section on Bibliography; Section on Classification and Indexing. Booklet 40.

    ERIC Educational Resources Information Center

    International Federation of Library Associations, The Hague (Netherlands).

    There are 16 papers in this collection from the Division of Bibliographic Control: (1) "Report from the Section on Cataloging" (Tom Delsey); (2) "Section on Bibliography Report" (B. C. Bloomfield); (3) "Report from the Section on Classification and Indexing" (Robert P. Holley); (4) "The Cost of Cataloging" (French and English versions; Genevieve…

  9. Assessing the economic impact of immunisation against East Coast fever: a case study in coast province, Kenya.

    PubMed

    Mukhebi, A W; Kariuki, D P; Mussukuya, E; Mullins, G; Ngumi, P N; Thorpe, W; Perry, B D

    1995-07-01

    The cost of immunising cattle against East Coast fever by the infection and treatment method has been calculated for a pilot scheme in Kaloleni Division of the Coast Province of Kenya by using a spreadsheet model. The cost was calculated to be KSh 544 (US$25) per animal (in 1990 values). If a farmer were to bear all this cost, immunisation would be financially profitable in grade cattle, but the benefits of immunisation would not be sufficient to justify the immunisation of zebu cattle. For these animals, the cost of immunisation would have to be in the range of KSh 230 to KSh 415 per animal, or the farm-gate price of milk would have to increase by at least 80 per cent from KSh 7.50 to 13.50/litre, or the government would have to subsidise the cost either partially or fully. The first two possibilities are realistic, because the costs of routine immunisation are likely to be lower than for the pilot scheme, and because the increasing demand for milk is likely to push up prices in the liberalised markets. If both the grade and zebu cattle in Kaloleni Division were targets for immunisation, it is estimated that there would be 14,500 head for immunisation annually, costing an estimated KSh 8 million. The spreadsheet model used to assess the economics of immunisation in the Kaloleni Division could be applied to determine the government or private veterinary service charges for immunisation that would be financially profitable to farmers in a defined cattle production system in any division, district or country. The model could also be used to estimate the annual total number of cattle for immunisation in a target cattle production system and thus help with the financial planning for the exercise.

  10. 42 CFR 7.4 - Schedule of charges.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... is available from the Division of Scientific Resources, Centers for Disease Control, 1600 Clifton..., and a proportionate share of management and administrative costs), and the cost of particular...

  11. 42 CFR 7.4 - Schedule of charges.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... is available from the Division of Scientific Resources, Centers for Disease Control, 1600 Clifton..., and a proportionate share of management and administrative costs), and the cost of particular...

  12. 28 CFR 100.12 - Reasonable costs.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... ASSISTANCE FOR LAW ENFORCEMENT ACT OF 1994 § 100.12 Reasonable costs. (a) A cost is reasonable if, in its... competitive business. Reasonableness of specific costs must be examined with particular care in connection with the carrier or its separate divisions that may not be subject to effective competitive restraints...

  13. 28 CFR 100.12 - Reasonable costs.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... ASSISTANCE FOR LAW ENFORCEMENT ACT OF 1994 § 100.12 Reasonable costs. (a) A cost is reasonable if, in its... competitive business. Reasonableness of specific costs must be examined with particular care in connection with the carrier or its separate divisions that may not be subject to effective competitive restraints...

  14. 21 CFR 10.30 - Citizen petition.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... requested action on: (1) Cost (and price) increases to industry, government, and consumers; (2) productivity... and in the following form: (Date) Division of Dockets Management, Food and Drug Administration... section and § 10.20 will be filed by the Division of Dockets Management, stamped with the date of filing...

  15. 75 FR 67767 - Notice of Lodging of Settlement Agreement Under the Comprehensive Environmental Response...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-03

    ... Chief, Environmental Enforcement Section, Environment and Natural Resources Division. [FR Doc. 2010... Debtor's Portland Harbor Superfund Site; and (3) natural resource damages and assessment costs, incurred... should be addressed to the Acting Assistant Attorney General, Environment and Natural Resources Division...

  16. An analysis of total quality management in Aeronautical Systems Division

    NASA Astrophysics Data System (ADS)

    Caudle, Mark D.

    1991-09-01

    This study investigated the major schools of thought on various aspects of quality management and quality improvement. Areas covered included definitions of waste and quality, views on the cost of quality, tools and techniques used for quality improvement, and management philosophies and frameworks for continuous improvement. In addition, this study analyzed the structure and training content of the current Total Quality Management program at Aeronautical Systems Division (ASD). Pre- and post-test surveys on employee attitudes toward organizational effectiveness were analyzed from the Advanced Cruise Missile System Program Office (SPO), the F-15 SPO, and the ASD Deputy Chief of Staff for Human Resources (ASD/DP). Data was supplemented with semi-structured, personal interviews with ASD personnel involved in TQM. Survey analysis showed that the ACM SPO significantly improved, ASD/DP significantly digressed, and the F-15 SPO remained basically consistent. This led to the conclusion that ASD allows too much flexibility in the implementation of TQM in the three-letter organizations.

  17. Cartographic applications software

    USGS Publications Warehouse

    ,

    1992-01-01

    The Office of the Assistant Division Chief for Research, National Mapping Division, develops computer software for the solution of geometronic problems in the fields of surveying, geodesy, remote sensing, and photogrammetry. Software that has been developed using public funds is available on request for a nominal charge to recover the cost of duplication.

  18. 75 FR 18751 - FBI Criminal Justice Information Services Division User Fees

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-13

    ... Standards (SFFAS-4): Managerial Cost Accounting Concepts and Standards for the Federal Government; and other relevant financial management directives, BearingPoint developed a cost accounting methodology and related... management process that provides information about the relationships between inputs (costs) and outputs...

  19. The impact of surgeon choice on the cost of performing laparoscopic appendectomy.

    PubMed

    Chu, Thomas; Chandhoke, Ryan A; Smith, Paul C; Schwaitzberg, Steven D

    2011-04-01

    While laparoscopic appendectomy (LA) can be performed using a myriad of techniques, the cost of each method varies. The purpose of this study is to analyze the effects of surgeon choice of technique on the cost of key steps in LA. Surgeon operative notes, hospital invoice lists, and surgeon instrumentation preference sheets were obtained for all LA cases in 2008 at Cambridge Health Alliance (CHA). Only cases (N = 89) performed by fulltime staff general surgeons (N = 8) were analyzed. Disposable costs were calculated for the following components of LA: port access, mesoappendix division, and management of the appendiceal stump. The actual cost of each disposable was determined based on the hospital's materials management database. Actual hospital reimbursements for LA in 2008 were obtained for all payers and compared with the disposable cost per case. Disposable cost per case for the three portions analyzed for 126 theoretical models were calculated and found to range from US $81 to US $873. The surgeon with the most cost-effective preferred method (US $299) utilized one multi-use endoscopic clip applier for mesoappendix division, two commercially available pretied loops for management of the appendiceal stump, and three 5-mm trocars as their preferred technique. The surgeon with the least cost-effective preferred method (US $552) utilized two staple firings for mesoappendix division, one staple firing for management of the appendiceal stump, and 12/5/10-mm trocars for access. The two main payers for LA patients were Medicaid and Health Safety Net, whose total hospital reimbursements ranged from US $264 to US $504 and from US $0 to US $545 per case, respectively, for patients discharged on day 1. Disposable costs frequently exceeded hospital reimbursements. Currently, there is no scientific literature that clearly illustrates a superior surgical method for performing these portions of LA in routine cases. This study suggests that surgeons should review the cost implications of their practice and to find ways to provide the most cost-effective care without jeopardizing clinical outcome.

  20. 2003 IDA Cost Research Symposium: Cost of Evolutionary Acquisition/Spiral Development

    DTIC Science & Technology

    2003-08-01

    Louis, Missouri”, IDA Paper P-3548 “Econometric Modeling of Acquisition Category I Systems at the Lockheed- Martin Plant in Marietta , Georgia”, IDA...Systems Command (NAVSEA)..................................................... B- 71 Naval Surface Warfare Center, Dahlgren Division (NSWCDD...cost estimates and reports on life-cycle costs of major defense acquisition programs (MDAPs) in Acquisition Category ID (see Reference [1]). Cost

  1. Waste minimization/pollution prevention study of high-priority waste streams

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ogle, R.B.

    1994-03-01

    Although waste minimization has been practiced by the Metals and Ceramics (M&C) Division in the past, the effort has not been uniform or formalized. To establish the groundwork for continuous improvement, the Division Director initiated a more formalized waste minimization and pollution prevention program. Formalization of the division`s pollution prevention efforts in fiscal year (FY) 1993 was initiated by a more concerted effort to determine the status of waste generation from division activities. The goal for this effort was to reduce or minimize the wastes identified as having the greatest impact on human health, the environment, and costs. Two broadmore » categories of division wastes were identified as solid/liquid wastes and those relating to energy use (primarily electricity and steam). This report presents information on the nonradioactive solid and liquid wastes generated by division activities. More specifically, the information presented was generated by teams of M&C staff members empowered by the Division Director to study specific waste streams.« less

  2. Cost Comparative Analysis of Blast Mitigation Technologies with Regard to Explosive Remnants of War (ERW)

    DTIC Science & Technology

    2011-12-01

    Division, 1998) ............................................................................13  Figure 7:  Papercrete Block with Mortar (From The Center for...40.5 inches x 10 1/8 inch wide): 2 X $71.25 = $142.50 - 55-gallon industrial plastic trash cans: $55.00 20 - 5-gallon 3M Fastbond insulation...off in physical security with regard to the access of a plastic container, compared to a steel box with a high-security hasp lock. Added security

  3. Optical frequency comb generation with high tone-to-noise ratio for large-capacity wavelength division multiplexed passive optical network

    NASA Astrophysics Data System (ADS)

    Ullah, Rahat; Liu, Bo; Zhang, Qi; Tian, Qinghua; Tian, Feng; Qu, Zhaowei; Yan, Cheng; Khan, Muhammad Saad; Ahmad, Ibrar; Xin, Xiangjun

    2015-11-01

    We propose a technique for the generation of optical frequency comb from a single source, which reduces the costs of optical access networks. Two Mach-Zehnder modulators are cascaded with one phase modulator driven by radiofrequency signals. With 10-GHz frequency spacing, the generated 40 optical multicarriers have good tone-to-noise ratio with least excursions in their comb lines. The laser array at the optical line terminal of the conventional wavelength division multiplexed passive optical network (WDM-PON) system has been replaced with optical frequency comb generator (OFCG), which may result in cost-effective optical line terminal (OLT) supporting a large-capacity WDM-PON system. Of 40 carriers generated, each carrier carries 10 Gbps data based on differential phase-shift keying. Four hundred Gbps multiplexed data from all channels are successfully transmitted through a fiber span of 25 km with negligible power penalties. Part of the downlink signal is used in uplink transmission at optical network unit where intensity-modulated on-off keying is deployed for remodulation. Theoretical analysis of the proposed WDM-PON system based on OFCG are in good agreement with simulation results. The metrics considered for the analysis of the proposed OFCG in a WDM-PON system are power penalties of the full-duplex transmission, eye diagrams, and bit error rate.

  4. The mechanisms of labor division from the perspective of individual optimization

    NASA Astrophysics Data System (ADS)

    Zhu, Lirong; Chen, Jiawei; Di, Zengru; Chen, Liujun; Liu, Yan; Stanley, H. Eugene

    2017-12-01

    Although the tools of complexity research have been applied to the phenomenon of labor division, its underlying mechanisms are still unclear. Researchers have used evolutionary models to study labor division in terms of global optimization, but focusing on individual optimization is a more realistic, real-world approach. We do this by first developing a multi-agent model that takes into account information-sharing and learning-by-doing and by using simulations to demonstrate the emergence of labor division. We then use a master equation method and find that the computational results are consistent with the results of the simulation. Finally we find that the core underlying mechanisms that cause labor division are learning-by-doing, information cost, and random fluctuation.

  5. Futurepath: The Story of Research and Technology at NASA Lewis Research Center. Structures for Flight Propulsion, ARC Sprayed Monotape, National Aero-Space Plane

    NASA Technical Reports Server (NTRS)

    1989-01-01

    The story of research and technology at NASA Lewis Research Center's Structures Division is presented. The job and designs of the Structures Division needed for flight propulsion is described including structural mechanics, structural dynamics, fatigue, and fracture. The video briefly explains why properties of metals used in structural mechanics need to be tested. Examples of tests and simulations used in structural dynamics (bodies in motion) are briefly described. Destructive and non-destructive fatigue/fracture analysis is also described. The arc sprayed monotape (a composite material) is explained, as are the programs in which monotape plays a roll. Finally, the National Aero-Space Plane (NASP or x-30) is introduced, including the material development and metal matrix as well as how NASP will reduce costs for NASA.

  6. 78 FR 77128 - Notice to All Interested Parties of the Termination of the Receivership of 10186-The La Coste...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-20

    ... Receivership of 10186--The La Coste National Bank La Coste, Texas Notice is hereby given that the Federal... The La Coste National Bank on February 19, 2010. The liquidation of the receivership assets has been...: Federal Deposit Insurance Corporation, Division of Resolutions and Receiverships, Attention: Receivership...

  7. 75 FR 7291 - Division of Federal Employees' Compensation; Proposed Extension of the Approval of Information...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-18

    ... other for-profit, not-for-profit institutions. Total Respondents: 25. Total Annual Responses: 100... Burden Cost (capital/startup): $0. Total Burden Cost (operating/maintenance): $47. Comments submitted in...

  8. 75 FR 66110 - Guidelines for Use of Stored Specimens and Access to Ancillary Data and Proposed Cost Schedule...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-27

    ... repository of datasets from completed studies, biospecimens, and ancillary data. The Division intends to make... Sharing Policy. The Division has established an internal committee, the Biospecimen Repository Access and Data Sharing Committee (BRADSC), to oversee the repository access and data sharing program. The purpose...

  9. 77 FR 516 - Notice of Lodging of Proposed Natural Resource Damages Consent Decree Under the Comprehensive...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-05

    ... of Interior's remaining unpaid past natural resource damage assessment costs, which amount to $59,750... Assistant Attorney General, Environment and Natural Resources Division, and either emailed to pubcomment-ees... Enforcement Section, Environment and Natural Resources Division. [FR Doc. 2011-33803 Filed 1-4-12; 8:45 am...

  10. 76 FR 20372 - Notice of Lodging of Consent Decree and Settlement Agreement Regarding Natural Resource Damage...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-12

    ..., Assistant Section Chief, Environmental Enforcement Section, Environment and Natural Resources Division. [FR... resolves claims for natural resource damages and assessment costs of the United States Department of the..., Environment and Natural Resources Division, and either e-mailed to [email protected] or mailed to...

  11. Creative Partnership Structures: Innovative Ways To Link Colleges and Employers.

    ERIC Educational Resources Information Center

    Meighan, John E.

    To provide cost effective, quality training to businesses and industrial organizations in central Ohio, Columbus State Community College (CSCC) established the Business and Industry Training Division (BITD) in 1986. The Division has increased the sales of training programs and the number of credit and non-credit class sections, and in 1994,…

  12. Divisions of general practice in Australia: how do they measure up in the international context?

    PubMed Central

    Smith, Judith; Sibthorpe, Beverly

    2007-01-01

    Background Since the late 1980s, there has been evidence of an international trend towards more organised primary care. This has taken a number of forms including the emergence of primary care organisations. Underpinning such developments is an inherent belief in evidence that suggests that well-developed primary care is associated with improved health outcomes and greater cost-effectiveness within health systems. In Australia, primary care organisations have emerged as divisions of general practice. These are professionally-led, regionally-based, and largely government-funded voluntary associations of general practitioners that seek to co-ordinate local primary care services, and improve the quality of care and health outcomes for local communities. Discussion In this paper, we examine and debate the development of divisions in the international context, using six roles of primary care organisations outlined in published research. The six roles that are used as the basis for the critique are the ability of primary care organisations to: improve health outcomes; manage demand and control costs; engage primary care physicians; enable greater integration of health services; develop more accessible services in community and primary care settings; and enable greater scrutiny and assurance of quality of primary care services. Summary We conclude that there has been an evolutionary approach to divisions' development and they now appear embedded as geographically-based planning and development organisations within the Australian primary health care system. The Australian Government has to date been cautious in its approach to intervention in divisions' direction and performance. However, options for the next phase include: making greater use of contracts between government and divisions; introducing and extending proposed national quality targets for divisions, linked with financial or other incentives for performance; government sub-contracting with state-based organisations to act as purchasers of care; pursuing a fund-holding approach within divisions; and developing divisions as a form of health maintenance organisation. The challenge for the Australian Government, should it wish to see divisions' role expand, is to find mechanisms to enable this without compromising the relatively strong GP engagement that increasingly distinguishes divisions of general practice within the international experience of primary care organisations. PMID:17626642

  13. Program Tracks Cost Of Travel

    NASA Technical Reports Server (NTRS)

    Mauldin, Lemuel E., III

    1993-01-01

    Travel Forecaster is menu-driven, easy-to-use computer program that plans, forecasts cost, and tracks actual vs. planned cost of business-related travel of division or branch of organization and compiles information into data base to aid travel planner. Ability of program to handle multiple trip entries makes it valuable time-saving device.

  14. The case of the downsizing decision.

    PubMed

    Train, A S

    1991-01-01

    New CEO Charles Rampart's decision to make deep across-the-board cuts at Universal Products Company, Ltd. presents division manager Andrew Jordan with a thorny problem. Plagued by slow growth, a declining stock price, and an increasingly skeptical investment community, UPC needs to control costs and control them fast. But Jordan's division is the most profitable in the company, and the 11% cut proposed by Rampart could destroy already shaky morale and seriously threaten the division's ability to compete. "There comes a time in every manager's career when he has to fight a bad decision made by his boss," argues Sam Godwyn, Jordan's vice president for marketing and sales. "To cut across the board is to take a blunt axe to the company when a surgeon's scalpel is called for." He suggests it is better to line up support for an alternative plan that links cuts to a long-term strategy and that differentiates between successful and unsuccessful divisions. "It would be a terrible mistake for us to focus only on the narrow needs of the division when the future of the whole company is at stake," counters Mary Wyatt, Jordan's vice president for finance. Yes, the downsizing will hurt the division in the short term, but the real issue is getting behind the new CEO. Supporting the downsizing decision is a necessary investment in this future credibility and effectiveness--whatever the short-term costs. Four commentators debate Jordan's dilemma and how he should resolve it.

  15. Installation Restoration Program (IRP) Stage 3, Operable Unit B engineering Evaluation/Cost Analysis - Environmental Assessment for McClellan AFB/EM, McClellan AFB, California

    DTIC Science & Technology

    1990-12-01

    Force ......,,...Human Systems Division (AFSC) .................. . . .. . . RP Pr ra -Offic (HSDIYAO) .............. ........... Brooks Air Force...intra- system piping. Six months to one year would be required to complete and integrate these components. EECA/021491/jlh 6-39 RADIAN COlVOR AT 1O IN... system capacity has been exceeded. It is a possibility that during severe storm events, the groundwater extraction wells will be shut down to avoid

  16. The Impact of Cost Sharing on Internal Efficiency of Public Secondary Schools in Ndivisi Division, Bungoma District Kenya

    ERIC Educational Resources Information Center

    Kiveu, Noah Murumba; Mayio, Julius

    2009-01-01

    Adoption of cost sharing policy in education has witnessed the return to communities and parents a substantial proportion of financial responsibility for schooling. With increased poverty levels, many parents and communities have not been able to meet the cost requirements under cost sharing policy. Thus their investment in education and support…

  17. Work management plan for data systems and analysis directorate

    NASA Technical Reports Server (NTRS)

    Nichols, L. R.

    1979-01-01

    A contract with the Data Systems and Analysis Directorate contains a specified level of resources related to a specific set of work in support of three divisions within the Data Systems and Analysis Directorate. The divisions are Institutional Data Systems Division, Ground Data Systems Division, and Mission Planning and Analysis Division. The Statement of work defines at a functional requirements level the type of support to be provided to the three divisions. The contract provides for further technical direction to the contractor through issuance of Job Orders. The Job order is the prime method of further defining the work to be done, allocating a portion of the total resources in the contract to the defined tasks, and further delegating technical responsibility.

  18. 78 FR 22295 - Notice of Lodging of Proposed Consent Decree Under the Comprehensive Environmental Response...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-15

    ... claims for natural resource damages and assessment costs (``NRD'') of the United States Department of... should be addressed to the Assistant Attorney General, Environment and Natural Resources Division, and..., Environment and Natural Resources Division. [FR Doc. 2013-08719 Filed 4-12-13; 8:45 am] BILLING CODE 4410-15-P ...

  19. DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    The Coal and Electric Data and Renewables Division; Office of Coal, Nuclear, Electric and Alternate Fuels, Energy Information Administration (EIA), Department of Energy prepares the EPM. This publication provides monthly statistics at the State, Census division, and U.S. levels for net generation, fossil fuel consumption and stocks, quantity and quality of fossil fuels, cost of fossil fuels, electricity retail sales, associated revenue, and average revenue per kilowatthour of electricity sold. In addition, data on net generation, fuel consumption, fuel stocks, quantity and cost of fossil fuels are also displayed for the North American Electric Reliability Council (NERC) regions. The EIAmore » publishes statistics in the EPM on net generation by energy source; consumption, stocks, quantity, quality, and cost of fossil fuels; and capability of new generating units by company and plant.« less

  20. Cost analysis of immunisation against east coast fever on smallholder dairy farms in Kenya.

    PubMed

    Muraguri, G R; Mbogo, S K; McHardy, N; Kariuki, D P

    1998-03-27

    A spreadsheet model was developed and used to estimate the total cost of immunising cattle against East Coast fever (ECF) based on the infection-and-treatment method. Using data from an immunisation trial carried out on 102 calves and yearlings on 64 farms in the Githunguri division, Kiambu district, Kenya, a reference base scenario of a mean herd of five animals, a 10% rate of reaction to immunisation and a 2-day interval monitoring regimen (a total of 10 farm visits) was simulated. Under these conditions, the mean cost of immunisation per animal was US$16.48 (Ksh 955.78); this was equivalent to US$82.39 (Ksh 4778.90) per five-animal farm. A commonly reported reactor rate of 3% would decrease the cost of US$14.63 (Ksh 848.29) per animal. Reducing the number of farm monitoring visits from 10 to 7 would reduce the total cost by 10%, justified if farmers are trained to undertake some of the monitoring work. The fixed costs were 53% of the total cost of immunisation per farm. The cost of immunisation decreased with increasing number of animals per farm, showing economies of scale.

  1. Power Budget Analysis of Colorless Hybrid WDM/TDM-PON Scheme Using Downstream DPSK and Re-modulated Upstream OOK Data Signals

    NASA Astrophysics Data System (ADS)

    Khan, Yousaf; Afridi, Muhammad Idrees; Khan, Ahmed Mudassir; Rehman, Waheed Ur; Khan, Jahanzeb

    2014-09-01

    Hybrid wavelength-division multiplexed/time-division multiplexed passive optical access networks (WDM/TDM-PONs) combine the advance features of both WDM and TDM PONs to provide a cost-effective access network solution. We demonstrate and analyze the transmission performances and power budget issues of a colorless hybrid WDM/TDM-PON scheme. A 10-Gb/s downstream differential phase shift keying (DPSK) and remodulated upstream on/off keying (OOK) data signals are transmitted over 25 km standard single mode fiber. Simulation results show error free transmission having adequate power margins in both downstream and upstream transmission, which prove the applicability of the proposed scheme to future passive optical access networks. The power budget confines both the PON splitting ratio and the distance between the Optical Line Terminal (OLT) and Optical Network Unit (ONU).

  2. ADP Analysis project for the Human Resources Management Division

    NASA Technical Reports Server (NTRS)

    Tureman, Robert L., Jr.

    1993-01-01

    The ADP (Automated Data Processing) Analysis Project was conducted for the Human Resources Management Division (HRMD) of NASA's Langley Research Center. The three major areas of work in the project were computer support, automated inventory analysis, and an ADP study for the Division. The goal of the computer support work was to determine automation needs of Division personnel and help them solve computing problems. The goal of automated inventory analysis was to find a way to analyze installed software and usage on a Macintosh. Finally, the ADP functional systems study for the Division was designed to assess future HRMD needs concerning ADP organization and activities.

  3. Generalized Support Software: Domain Analysis and Implementation

    NASA Technical Reports Server (NTRS)

    Stark, Mike; Seidewitz, Ed

    1995-01-01

    For the past five years, the Flight Dynamics Division (FDD) at NASA's Goddard Space Flight Center has been carrying out a detailed domain analysis effort and is now beginning to implement Generalized Support Software (GSS) based on this analysis. GSS is part of the larger Flight Dynamics Distributed System (FDDS), and is designed to run under the FDDS User Interface / Executive (UIX). The FDD is transitioning from a mainframe based environment to systems running on engineering workstations. The GSS will be a library of highly reusable components that may be configured within the standard FDDS architecture to quickly produce low-cost satellite ground support systems. The estimates for the first release is that this library will contain approximately 200,000 lines of code. The main driver for developing generalized software is development cost and schedule improvement. The goal is to ultimately have at least 80 percent of all software required for a spacecraft mission (within the domain supported by the GSS) to be configured from the generalized components.

  4. Cost-Analysis of Seven Nosocomial Outbreaks in an Academic Hospital.

    PubMed

    Dik, Jan-Willem H; Dinkelacker, Ariane G; Vemer, Pepijn; Lo-Ten-Foe, Jerome R; Lokate, Mariëtte; Sinha, Bhanu; Friedrich, Alex W; Postma, Maarten J

    2016-01-01

    Nosocomial outbreaks, especially with (multi-)resistant microorganisms, are a major problem for health care institutions. They can cause morbidity and mortality for patients and controlling these costs substantial amounts of funds and resources. However, how much is unclear. This study sets out to provide a comparable overview of the costs of multiple outbreaks in a single academic hospital in the Netherlands. Based on interviews with the involved staff, multiple databases and stored records from the Infection Prevention Division all actions undertaken, extra staff employment, use of resources, bed-occupancy rates, and other miscellaneous cost drivers during different outbreaks were scored and quantified into Euros. This led to total costs per outbreak and an estimated average cost per positive patient per outbreak day. Seven outbreaks that occurred between 2012 and 2014 in the hospital were evaluated. Total costs for the hospital ranged between €10,778 and €356,754. Costs per positive patient per outbreak day, ranged between €10 and €1,369 (95% CI: €49-€1,042), with a mean of €546 and a median of €519. Majority of the costs (50%) were made because of closed beds. This analysis is the first to give a comparable overview of various outbreaks, caused by different microorganisms, in the same hospital and all analyzed with the same method. It shows a large variation within the average costs due to different factors (e.g. closure of wards, type of ward). All outbreaks however cost considerable amounts of efforts and money (up to €356,754), including missed revenue and control measures.

  5. Costs Associated with Endangered Species Act Compliance

    DTIC Science & Technology

    2013-08-01

    August 2013 2 on economic costs or values related to endangered species costs or values, focuses primarily on Contingent Valuation Method studies...of species preservation (Lew, Layton, and Rowe 2010; Wallmo 2006). Most studies consider public valuation of species preservation, and not costs of...2012, NMFS 2006, U.S. Army Engineer, Mississippi Valley Division 2012, Kozlowski 1993, PFMC 2002) and through development of expenditure categories

  6. Analysis of academic programs: comparing nursing and other university majors in the application of a quality, potential and cost model.

    PubMed

    Booker, Kathy; Hilgenberg, Cheryl

    2010-01-01

    Nursing is often considered expensive in the cost analysis of academic programs. Yet nursing programs have the power to attract many students, and the national nursing shortage has resulted in a high demand for nurses. Methods to systematically assess programs across an entire university academic division are often dissimilar in technique and outcome. At a small, private, Midwestern university, a model for comprehensive program assessment, titled the Quality, Potential and Cost (QPC) model, was developed and applied to each major offered at the university through the collaborative effort of directors, chairs, deans, and the vice president for academic affairs. The QPC model provides a means of equalizing data so that single measures (such as cost) are not viewed in isolation. It also provides a common language to ensure that all academic leaders at an institution apply consistent methods for assessment of individual programs. The application of the QPC model allowed for consistent, fair assessments and the ability to allocate resources to programs according to strategic direction. In this article, the application of the QPC model to School of Nursing majors and other selected university majors will be illustrated. Copyright 2010 Elsevier Inc. All rights reserved.

  7. Cost and schedule estimation study report

    NASA Technical Reports Server (NTRS)

    Condon, Steve; Regardie, Myrna; Stark, Mike; Waligora, Sharon

    1993-01-01

    This report describes the analysis performed and the findings of a study of the software development cost and schedule estimation models used by the Flight Dynamics Division (FDD), Goddard Space Flight Center. The study analyzes typical FDD projects, focusing primarily on those developed since 1982. The study reconfirms the standard SEL effort estimation model that is based on size adjusted for reuse; however, guidelines for the productivity and growth parameters in the baseline effort model have been updated. The study also produced a schedule prediction model based on empirical data that varies depending on application type. Models for the distribution of effort and schedule by life-cycle phase are also presented. Finally, this report explains how to use these models to plan SEL projects.

  8. Two Outstanding Investigator Awards Go to Division of Cancer Prevention Grantees | Division of Cancer Prevention

    Cancer.gov

    NCI's Outstanding Investigator Award supports accomplished leaders in cancer research, who are providing significant contributions toward understanding cancer and developing applications that may lead to a breakthrough in biomedical, behavioral, or clinical cancer research. The Award provides up to $600,000 in direct costs per year for 7 years, allowing substantial time for

  9. Information technology as a key enabler in preparing for competition: ComEd`s Kincaid Generating Station, a work in progress

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Borth, F.C. III; Thompson, J.W.; Mishaga, J.M.

    1996-11-01

    Through ComEd Fossil (Generating) Division`s Competitive Action Plan (CAP) evaluation changes have been identified which are necessary to improve generating station performance. These changes are intended to improve both station reliability and financial margins, and are essential for stations to be successful in a competitive marketplace. Plant upgrades, advanced equipment stewardship, and personnel reductions have been identified as necessary steps in achieving industry leadership and competitive advantage. To deal effectively with plant systems and contend in the competitive marketplace Information Technology (IT) solutions to business problems are being developed. Data acquisition, storage, and retrieval are being automated through use ofmore » state-of-the-art Data Historians. Total plant, high resolution, long term process information will be accessed through Local/Wide Area Networks (LAN/WAN) connections from desktop PC`s. Generating unit Thermal Performance Monitors accessing the Data Historian will analyze plant and system performance enabling reductions in operating costs, and improvements in process control. As inputs to proactive maintenance toolsets this data allows anticipation of equipment service needs, advanced service scheduling, and cost/benefit analysis. The ultimate goal is to optimize repair needs with revenue generation. Advanced applications building upon these foundations will bring knowledge of the costs associated with all the products a generating station offers its customer(s). An overall design philosophy along with preliminary results is presented; these results include shortfalls, lessons learned, and future options.« less

  10. Destination directed packet switch architecture for a 30/20 GHz FDMA/TDM geostationary communication satellite network

    NASA Technical Reports Server (NTRS)

    Ivancic, William D.; Shalkhauser, Mary JO

    1991-01-01

    Emphasis is on a destination directed packet switching architecture for a 30/20 GHz frequency division multiplex access/time division multiplex (FDMA/TDM) geostationary satellite communication network. Critical subsystems and problem areas are identified and addressed. Efforts have concentrated heavily on the space segment; however, the ground segment was considered concurrently to ensure cost efficiency and realistic operational constraints.

  11. Circuit-switch architecture for a 30/20-GHz FDMA/TDM geostationary satellite communications network

    NASA Technical Reports Server (NTRS)

    Ivancic, William D.

    1992-01-01

    A circuit switching architecture is described for a 30/20 GHz frequency division, multiple access uplink/time division multiplexed downlink (FDMA/TDM) geostationary satellite communications network. Critical subsystems and problem areas are identified and addressed. Work was concentrated primarily on the space segment; however, the ground segment was considered concurrently to ensure cost efficiency and realistic operational constraints.

  12. Destination-directed, packet-switching architecture for 30/20-GHz FDMA/TDM geostationary communications satellite network

    NASA Technical Reports Server (NTRS)

    Ivancic, William D.; Shalkhauser, Mary JO

    1992-01-01

    A destination-directed packet switching architecture for a 30/20-GHz frequency division multiple access/time division multiplexed (FDMA/TDM) geostationary satellite communications network is discussed. Critical subsystems and problem areas are identified and addressed. Efforts have concentrated heavily on the space segment; however, the ground segment has been considered concurrently to ensure cost efficiency and realistic operational constraints.

  13. Electric Power Monthly, June 1990

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1990-09-13

    The EPM is prepared by the Electric Power Division; Office of Coal, Nuclear, Electric and Alternate Fuels, Energy Information Administration (EIA), Department of Energy. This publication provides monthly statistics at the national, Census division, and State levels for net generation, fuel consumption, fuel stocks, quantity and quality of fuel, electricity sales, and average revenue per kilowatthour of electricity sold. Data on net generation are also displayed at the North American Electric Reliability Council (NERC) region level. Additionally, company and plant level information are published in the EPM on capability of new plants, net generation, fuel consumption, fuel stocks, quantity andmore » quality of fuel, and cost of fuel. Quantity, quality, and cost of fuel data lag the net generation, fuel consumption, fuel stocks, electricity sales, and average revenue per kilowatthour data by 1 month. This difference in reporting appears in the national, Census division, and State level tables. However, at the plant level, all statistics presented are for the earlier month for the purpose of comparison. 40 tabs.« less

  14. Satellite Power Systems (SPS) concept definition study (Exhibit D). Volume 6, part 1: Cost and Programmatics

    NASA Technical Reports Server (NTRS)

    Hanley, G. M.

    1981-01-01

    A summary of the cost data reviewed as well as conclusions and recommendations are presented. Cost and programmatic aspects of Rockwell's SPS CR-2 reference configuration were based on the results of several contracts with NASA and independent company-sponsored activities by the Space Operations and Satellite Systems Division of Rockwell International.

  15. Application of the Hardman methodology to the Single Channel Ground-Airborne Radio System (SINCGARS)

    NASA Technical Reports Server (NTRS)

    1984-01-01

    The HARDMAN methodology was applied to the various configurations of employment for an emerging Army multipurpose communications system. The methodology was used to analyze the manpower, personnel and training (MPT) requirements and associated costs, of the system concepts responsive to the Army's requirement for the Single Channel Ground-Airborne Radio System (SINCGARS). The scope of the application includes the analysis of two conceptual designs Cincinnati Electronics and ITT Aerospace/Optical Division for operating and maintenance support addressed through the general support maintenance echelon.

  16. FBI fingerprint identification automation study: AIDS 3 evaluation report. Volume 5: Current system evaluation

    NASA Technical Reports Server (NTRS)

    Mulhall, B. D. L.

    1980-01-01

    The performance, costs, organization and other characteristics of both the manual system and AIDS 2 were used to establish a baseline case. The results of the evaluation are to be used to determine the feasibility of the AIDS 3 System, as well as provide a basis for ranking alternative systems during the second phase of the JPL study. The results of the study were tabulated by subject, scope and methods, providing a descriptive, quantitative and qualitative analysis of the current operating systems employed by the FBI Identification Division.

  17. Solar System Exploration Division Strategic Plan, volume 1. Executive summary and overview

    NASA Technical Reports Server (NTRS)

    1991-01-01

    This first document is the first of a six-volume series presenting the Solar System Exploration Division's Strategic Plan for the 10-year period FY 1994 to FY 2003. The overall strategy is characterized by five fundamental precepts: (1) execute the current program; (2) improve the vitality of the program and the planetary science community; (3) initiate innovative, small, low-cost planetary missions; (4) initiate new major and moderate missions; and (5) prepare for the next generation of missions. This Strategic Plan describes in detail our proposed approach to accomplish these goals. Volume 1 provides first an Executive Summary of highlights of each of the six volumes, and then goes on to present an overview of the plan, including a discussion of the planning context and strategic approach. Volumes 2, 3, 4, and 5 describe in detail the initiatives proposed. An integral part of each of these volumes is a set of responses to the mission selection criteria questions developed by the Space and Earth Science Advisory Committee. Volume 2, Mission From Planet Earth, describes a strategy for exploring the Moon and Mars and sets forth proposed moderate missions--Lunar Observer and a Mars lander network. Volume 3, Pluto Flyby/Neptune Orbiter, discusses our proposed major new start candidate for the FY 1994 to FY 1998 time frame. Volume 4, Discovery, describes the Near-Earth Asteroid Rendezvous, as well as other candidates for this program of low-cost planetary missions. Volume 5, Toward Other Planetary Systems, describes a major research and analysis augmentation that focuses on extrasolar planet detection and the study of planetary system processes. Finally, Volume 6 summarizes the technology program that the division has structured around these four initiatives.

  18. Production cost analysis and use of pesticides in the transgenic and conventional corn crop [Zea mays (L.)] in the valley of San Juan, Tolima.

    PubMed

    Méndez, Kelly Avila; Chaparro Giraldo, Alejandro; Moreno, Giovanni Reyes; Castro, Carlos Silva

    2011-01-01

    A survey of 10 producers of conventional corn (Hybrids PAC 105 and Maximus) and 10 producers of transgenic corn (Pioneer Hybrid 30T17) was carried out in the municipality of Valle de San Juan in the territorial division of Tolima (Colombia), in order to analyze the differences in production costs and environmental impacts of these two agricultural technologies.  The environmental impacts were determined by calculating the field "Environmental Index Quotient" (EIQ). In the production cost analysis, a difference of 15% was found in benefit of the transgenic technology. The structure of costs of the transgenic technology was benefited by the reduced use of pesticides (insecticides and herbicides). In regards to production, the transgenic technology showed a greater yield, 5.22 ton/ha in comparison to 4.25 ton/ha the conventional technology, thus a 22% difference in yield. Finally, the EIQ calculation showed quantitative differences of 196.12 for the conventional technology (EIQ insecticides 165.14 + EIQ herbicides 30.98), while the transgenic technology was of 4.24 (EIQ insecticides 0 + EIQ herbicides 4.24). These results show a minor environmental impact when using the transgenic technology in comparison to the conventional technology, in regards to the use of insecticides and herbicides in a temporal, spatial and genotypical context analysis. :

  19. 75 FR 24796 - FBI Records Management Division National Name Check Program Section User Fees

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-06

    ... with generally accepted accounting principles, also include such expenses as capital investment... by RMD. Referencing OMB Circular A-25; the Statement of Federal Financial Accounting Standards (SFFAS... financial management directives, Grant Thornton developed a cost accounting methodology and related cost...

  20. Levelized cost-benefit analysis of proposed diagnostics for the Ammunition Transfer Arm of the US Army`s Future Armored Resupply Vehicle

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wilkinson, V.K.; Young, J.M.

    1995-07-01

    The US Army`s Project Manager, Advanced Field Artillery System/Future Armored Resupply Vehicle (PM-AFAS/FARV) is sponsoring the development of technologies that can be applied to the resupply vehicle for the Advanced Field Artillery System. The Engineering Technology Division of the Oak Ridge National Laboratory has proposed adding diagnostics/prognostics systems to four components of the Ammunition Transfer Arm of this vehicle, and a cost-benefit analysis was performed on the diagnostics/prognostics to show the potential savings that may be gained by incorporating these systems onto the vehicle. Possible savings could be in the form of reduced downtime, less unexpected or unnecessary maintenance, fewermore » regular maintenance checks. and/or tower collateral damage or loss. The diagnostics/prognostics systems are used to (1) help determine component problems, (2) determine the condition of the components, and (3) estimate the remaining life of the monitored components. The four components on the arm that are targeted for diagnostics/prognostics are (1) the electromechanical brakes, (2) the linear actuators, (3) the wheel/roller bearings, and (4) the conveyor drive system. These would be monitored using electrical signature analysis, vibration analysis, or a combination of both. Annual failure rates for the four components were obtained along with specifications for vehicle costs, crews, number of missions, etc. Accident scenarios based on component failures were postulated, and event trees for these scenarios were constructed to estimate the annual loss of the resupply vehicle, crew, arm. or mission aborts. A levelized cost-benefit analysis was then performed to examine the costs of such failures, both with and without some level of failure reduction due to the diagnostics/prognostics systems. Any savings resulting from using diagnostics/prognostics were calculated.« less

  1. 77 FR 16266 - Division of Longshore and Harbor Workers' Compensation; Proposed Extension of Existing Collection...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-20

    ... Number: LS-426. Affected Public: Individuals or households. Total Respondents: 1,100. Total Annual Responses: 1,100. Estimated Total Burden Hours: 275. Estimated Time per Response: 15 minutes. Frequency: On occasion. Total Burden Cost (capital/startup): $0. Total Burden Cost (operating/maintenance): $528.00...

  2. 76 FR 35218 - Federal Acquisition Regulation; Information Collection; Cost or Pricing Data Requirements and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-16

    ... INFORMATION CONTACT: Mr. Edward Chambers, Procurement Analyst, Acquisition Policy Division, GSA (202) 501-3221 or Edward.chambers@gsa.gov . SUPPLEMENTARY INFORMATION: A. Purpose The Truth in Negotiations Act... Than Cost or Pricing Data, in all correspondence. Dated: June 7, 2011. Millisa Gary, Acting Director...

  3. The Division of Indian Education of the Arizona Department of Education to the Bureau of Indian Affairs. 1971-1972 Annual Report.

    ERIC Educational Resources Information Center

    Turner, E. L., Jr.

    The Division of Indian Education of the Arizona Department of Education distributes Federal funds under the Johnson-O'Malley Act. These funds are provided to public schools and counties in Arizona with 3% or more American Indian children to help pay the cost of educating Indian children living on tax-exempt reservation lands. The host school…

  4. The Division of Indian Education of the Arizona Department of Education to the Bureau of Indian Affairs. 1972-73 Annual Report.

    ERIC Educational Resources Information Center

    Arizona State Dept. of Public Instruction, Phoenix, Div. of Indian Education.

    The Division of Indian Education, Arizona Department of Education, distrubutes Federal funds under the Johnson-O'Malley Act. The funds are provided to Arizona public schools and counties with 3% or more American Indian children to help pay the cost of educating children living on tax-exempt reservation lands. The host school district receives the…

  5. The National Shipbuilding Research Program: Producibility Cost Reductions through Alternative Materials and Processes

    DTIC Science & Technology

    1999-03-01

    steel; -60F - 250 F; nonflammable acrylic mod- ified methyl - methacrylate Hernon MI React 761; Act 63 two component unprimed steel/primed/ painted trowel... MSD ) of the University of Michigan Transportation Institute (UMTRI), the Shipyards Division of Avondale Industries, and Damilic Corporation, to...classification society requirements. This research was conducted by the research team of the Marine Systems Division ( MSD ) of the University of Michigan

  6. Thirty-Four Megabit Four-Channel Multiplexer

    DTIC Science & Technology

    1985-10-01

    person or conveying any rights or permis- sion to manufacture , use, or sell any patented invention thai ma> in any way be related thereto. WARNING...System (DCS) in Europe. The system is evolving from frequency division multiplex ( FDM ) to time division multiplex (TDM) equipment. The bulk of the...channel multi- plexer permits expansion by providing the spare MBS and 2.048~Mb/s data channels, and will do so with no additional cost

  7. Cost-effectiveness of the treatment of uncomplicated severe acute malnutrition by community health workers compared to treatment provided at an outpatient facility in rural Mali.

    PubMed

    Rogers, Eleanor; Martínez, Karen; Morán, Jose Luis Alvarez; Alé, Franck G B; Charle, Pilar; Guerrero, Saul; Puett, Chloe

    2018-02-20

    The Malian Nutrition Division of the Ministry of Health and Action Against Hunger tested the feasibility of integrating treatment of severe acute malnutrition (SAM) into the existing Integrated Community Case Management package delivered by community health workers (CHWs). This study assessed costs and cost-effectiveness of CHW-delivered care compared to outpatient facility-based care. Activity-based costing methods were used, and a societal perspective employed to include all relevant costs incurred by institutions, beneficiaries and communities. The intervention and control arm enrolled different numbers of children so a modelled scenario sensitivity analysis was conducted to assess the cost-effectiveness of the two arms, assuming equal numbers of children enrolled. In the base case, with unequal numbers of children in each arm, for CHW-delivered care, the cost per child treated was 244 USD and cost per child recovered was 259 USD. Outpatient facility-based care was less cost-effective at 442 USD per child and 501 USD per child recovered. The conclusions of the analysis changed in the modelled scenario sensitivity analysis, with outpatient facility-based care being marginally more cost-effective (cost per child treated is 188 USD, cost per child recovered is 214 USD), compared to CHW-delivered care. This suggests that achieving good coverage is a key factor influencing cost-effectiveness of CHWs delivering treatment for SAM in this setting. Per week of treatment, households receiving CHW-delivered care spent half of the time receiving treatment and three times less money compared with those receiving treatment from the outpatient facility. This study supports existing evidence that the delivery of treatment by CHWs is a cost-effective intervention, provided that good coverage is achieved. A major benefit of this strategy was the lower cost incurred by the beneficiary household when treatment is available in the community. Further research is needed on the implementation costs that would be incurred by the government to increase the operability of these results.

  8. The Management Information Needs of the Activity Level Comptroller within the Marine Corps.

    DTIC Science & Technology

    1983-03-01

    authority, cost accounting , and maintaining plant property account records and inventory. 14 . ., Sections that are usually maintained within accounting ...disbursing divisions are timekeeping, payroll, cost and reports, inventory account - ing, military pay records, public voucher, fiscal and savings bond...units incurring the expenses. PRIME was developed as a disciplined and mechanized way, to directly identify accountable cost separate from allocated

  9. The use of biospecimens in population-based research: a review of the National Cancer Institute's Division of Cancer Control and Population Sciences grant portfolio.

    PubMed

    Carrick, Danielle M; Mette, Eliza; Hoyle, Brittany; Rogers, Scott D; Gillanders, Elizabeth M; Schully, Sheri D; Mechanic, Leah E

    2014-08-01

    Over the past two decades, researchers have increasingly used human biospecimens to evaluate hypotheses related to disease risk, outcomes and treatment. We conducted an analysis of population-science cancer research grants funded by the National Cancer Institute (NCI) to gain a more comprehensive understanding of biospecimens and common derivatives involved in those studies and identify opportunities for advancing the field. Data available for 1,018 extramural, peer-reviewed grants (active as of July 2012) supported by the Division of Cancer Control and Population Sciences (DCCPS), the NCI Division that supports cancer control and population-science extramural research grants, were analyzed. 455 of the grants were determined to involve biospecimens or derivatives. The most common specimen types included were whole blood (51% of grants), serum or plasma (40%), tissue (39%), and the biospecimen derivative, DNA (66%). While use of biospecimens in molecular epidemiology has become common, biospecimens for behavioral and social research is emerging, as observed in our analysis. Additionally, we found the majority of grants were using already existing biospecimens (63%). Grants that involved use of existing biospecimens resulted in lower costs (studies that used existing serum/plasma biospecimens were 4.2 times less expensive) and more publications per year (1.4 times) than grants collecting new biospecimens. This analysis serves as a first step at understanding the types of biospecimen collections supported by NCI DCCPS. There is room to encourage increased use of archived biospecimens and new collections of rarer specimen and cancer types, as well as for behavioral and social research. To facilitate these efforts, we are working to better catalogue our funded resources and make that data available to the extramural community.

  10. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    The purpose of this report is to summarize the activities of the Analytical Chemistry Laboratory (ACL) at Argonne National Laboratory (ANL) for Fiscal Year (FY) 1993 (October 1992 through September 1993). This annual report is the tenth for the ACL and describes continuing effort on projects, work on new projects, and contributions of the ACL staff to various programs at ANL. The Analytical Chemistry Laboratory is a full-cost-recovery service center, with the primary mission of providing a broad range of analytical chemistry support services to the scientific and engineering programs at ANL. The ACL also has research programs in analyticalmore » chemistry, conducts instrumental and methods development, and provides analytical services for governmental, educational, and industrial organizations. The ACL handles a wide range of analytical problems. Some routine or standard analyses are done, but it is common for the Argonne programs to generate unique problems that require development or modification of methods and adaption of techniques to obtain useful analytical data. The ACL is administratively within the Chemical Technology Division (CMT), its principal ANL client, but provides technical support for many of the technical divisions and programs at ANL. The ACL has four technical groups--Chemical Analysis, Instrumental Analysis, Organic Analysis, and Environmental Analysis--which together include about 45 technical staff members. Talents and interests of staff members cross the group lines, as do many projects within the ACL.« less

  11. Negotiating user preferences, discrimination, and demand for migrant labour in long-term care.

    PubMed

    Shutes, Isabel; Walsh, Kieran

    2012-01-01

    The restructuring of long-term care for older people has been marked both by the role of the market and by the role of migrant labor. This article develops the analysis of these processes at the microlevel of the provision of care. It draws on data collected as part of a cross-national comparative study on the employment of migrant care workers in residential care homes and home care services for older people in England and Ireland. The article examines, first, the ways in which divisions of race, ethnicity, and citizenship shape the preferences of service providers/employers and some service users as regards who provides care. Second, it examines how the institutional context of quasi-markets in long-term care shapes the negotiation of demand for migrant labor, the racialized preferences of individual users, alongside the rights of care workers to non-discrimination. It is argued that market-oriented policies for personalization, as well as for cost containment, raise implications for divisions of race, ethnicity, and citizenship in the provision of long-term care. At the same time, those divisions point to the limits of framing care in terms of the preferences of the individual as opposed to the social relations in which care is embedded.

  12. Working toward quality in obstetric anesthesia: a business approach.

    PubMed

    Lynde, Grant C

    2017-06-01

    Physicians are increasingly required to demonstrate that they provide quality care. How does one define quality? A significant body of literature in industries outside of health care provides guidance on how to define appropriate metrics, create teams to troubleshoot problem areas, and sustain those improvements. The modern quality movement in the United States began in response to revolutionary gains in both quality and productivity in Japanese manufacturing in the 1980's. Applying these lessons to the healthcare setting has been slow. Hospitals are only now introducing tools such as failure mode and effect analysis, Lean and Six Sigma into their quality divisions and are seeing significant cost reductions and outcomes improvements. The review will discuss the process for creating an effective quality program for an obstetric anesthesia division. Sustainable improvements in delivered care need to be based on an evaluation of service line needs, defining appropriate metrics, understanding current process flows, changing and measuring those processes, and developing mechanisms to ensure the new processes are maintained.

  13. Installation Restoration Program Stage 3. Remedial Investigation/ Feasibility Study Elmendorf AFB, Alaska. Volume 2. Section 5 - Bibliography Text

    DTIC Science & Technology

    1990-05-01

    ELME’IDORF AFB, AK UNITED STATES AIR FORCE OCCUPATIONAL & ENVIRONMENTAL HEALTH LABORATORY (AFSC) ilb(. IiCAL Sr.(VICES DIVISION (AFOEHLi £3) I BROOKS AIR...UNITED STATES AIR FORCE OCCUPATIONAL AND ENVIRONMENTAL HEALTH LABORATORY (AFSC) TECHNICAL SERVICES DIVISION (AFOEHL/TS) BROOKS AIR FORCE BASE, TEXAS...the following criteria: technical feasibility, institutional requirements, environmental impacts, public health impacts, and cost. This Alternative

  14. Air Force Roles and Missions: A History

    DTIC Science & Technology

    1998-01-01

    armies fighting on the Western Front. In July, Foch gave Pershing tactical control of a sector in the Chateau- Thierry region, with only one division...In the battle at Chateau- Thierry in July, air squadrons flying support for the American division learned a costly lesson. Air units were deci- mated... Thierry , he saw Trenchard’s views on the need to concentrate air forces to achieve aerial superiority confirmed. The losses helped Mitchell convince

  15. 47 CFR 73.3617 - Information available on the Internet.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ....fcc.gov/mb/; the Audio Division's address is http://www.fcc.gov/mmb/audio; the Video Division's address is http://www.fcc.gov/mb/video; the Policy Division's address is http://www.fcc.gov/mb/policy; the Engineering Division's address is http://www.fcc.gov/mb/engineering; and the Industry Analysis Division's...

  16. 47 CFR 73.3617 - Information available on the Internet.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ....fcc.gov/mb/; the Audio Division's address is http://www.fcc.gov/mmb/audio; the Video Division's address is http://www.fcc.gov/mb/video; the Policy Division's address is http://www.fcc.gov/mb/policy; the Engineering Division's address is http://www.fcc.gov/mb/engineering; and the Industry Analysis Division's...

  17. 47 CFR 73.3617 - Information available on the Internet.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ....fcc.gov/mb/; the Audio Division's address is http://www.fcc.gov/mmb/audio; the Video Division's address is http://www.fcc.gov/mb/video; the Policy Division's address is http://www.fcc.gov/mb/policy; the Engineering Division's address is http://www.fcc.gov/mb/engineering; and the Industry Analysis Division's...

  18. 78 FR 11222 - Notice of Lodging of Proposed Consent Decree Under the Clean Water Act and the Comprehensive...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-15

    ..., Environmental Enforcement Section, Environment and Natural Resources Division. [FR Doc. 2013-03517 Filed 2-14-13... natural resource damages claims through restoration and reimbursement of assessment costs. The consent... and future assessment costs of the trustees and the Hillsborough County Environmental Protection...

  19. Virginia ridesharing statistics : methodologies for determining carpooler and vanpool average life bases and the average fuel economy of commuter vehicles.

    DOT National Transportation Integrated Search

    1985-01-01

    The objective of this research was to investigate methods of computing average life values for carpoolers and vanpools in Virginia. These statistics are to be used by the Rail and Public Transportation Division in evaluating the efficiency and cost-e...

  20. An Exploratory Study of Software Cost Estimating at the Electronic Systems Division.

    DTIC Science & Technology

    1976-07-01

    action’. to improve the software cost Sestimating proces., While thin research was limited to the M.nD onvironment, the same types of problema may exist...Methods in Social Science. Now York: Random House, 1969. 57. Smith, Ronald L. Structured Programming Series (Vol. XI) - Estimating Software Project

  1. Direct health services costs of providing assisted reproduction services in older women.

    PubMed

    Maheshwari, Abha; Scotland, Graham; Bell, Jacqueline; McTavish, Alison; Hamilton, Mark; Bhattacharya, Siladitya

    2010-02-01

    To assess the total health service costs incurred for each live birth achieved by older women undergoing IVF compared with costs in younger women. Retrospective cross-sectional analysis. In vitro fertilization unit and maternity hospital in a tertiary care setting. Women who underwent their first cycle of IVF between 1997 and 2006. Bottom-up costs were calculated for all interventions in the IVF cycle. Early pregnancy and antenatal care costs were obtained from National Health Service reference costs, Information Services Division Scotland, and local departmental costs. Cost per live birth. The mean cost per live birth (95% confidence interval [CI]) in women undergoing IVF at the age of > or =40 years was pound 40,320 (pound 27,105- pound 65,036), which is >2.5 times higher than those aged 35-39 years (pound 17,096 [pound 15,635- pound 18,937]). The cost per ongoing pregnancy was almost three times in women aged > or =40 (pound 31,642 [pound 21,241- pound 58,979]) compared with women 35-39 years of age (pound 11,300 [pound 10,006- pound 12,938]). The cost of a live birth after IVF rises significantly at the age of 40 years owing to lower success rates. Most of the extra cost is due to the low success of IVF treatment, but some of it is due to higher rates of early pregnancy loss. Copyright 2010 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

  2. An automated image analysis framework for segmentation and division plane detection of single live Staphylococcus aureus cells which can operate at millisecond sampling time scales using bespoke Slimfield microscopy

    NASA Astrophysics Data System (ADS)

    Wollman, Adam J. M.; Miller, Helen; Foster, Simon; Leake, Mark C.

    2016-10-01

    Staphylococcus aureus is an important pathogen, giving rise to antimicrobial resistance in cell strains such as Methicillin Resistant S. aureus (MRSA). Here we report an image analysis framework for automated detection and image segmentation of cells in S. aureus cell clusters, and explicit identification of their cell division planes. We use a new combination of several existing analytical tools of image analysis to detect cellular and subcellular morphological features relevant to cell division from millisecond time scale sampled images of live pathogens at a detection precision of single molecules. We demonstrate this approach using a fluorescent reporter GFP fused to the protein EzrA that localises to a mid-cell plane during division and is involved in regulation of cell size and division. This image analysis framework presents a valuable platform from which to study candidate new antimicrobials which target the cell division machinery, but may also have more general application in detecting morphologically complex structures of fluorescently labelled proteins present in clusters of other types of cells.

  3. Remarks by Drew S. Days III, Assistant Attorney General, Civil Rights Division, Department of Justice, Before the American Bar Association National Institute, Washington Hilton (Washington, D.C., on May 22, 1980).

    ERIC Educational Resources Information Center

    Days, Drew S., III

    In this speech the Assistant Attorney General for the Civil Rights Division of the Department of Justice discusses the impact of racial and sex discrimination on the nation. The author reflects on the high costs of discrimination, financially and socially, in terms of riot damage, underutilization of the work force, crime, and poor education. In…

  4. Cardiovascular preparticipation screening practices of college team physicians.

    PubMed

    Asplund, Chad A; Asif, Irfan M

    2014-07-01

    Determine the cardiovascular screening practices of college team physicians. Cross-sectional survey. Electronic mail with a link to a 9-item survey. American Medical Society for Sports Medicine college team physicians. Screening practices survey administered to college team physicians. Cardiovascular preparticipation screening practices including noninvasive cardiac screening (NICS) such as electrocardiogram (ECG) or echocardiogram. Two hundred twenty-four of 613 AMSSM members identifying themselves as college team physicians (36.5%) responded: National Collegiate Athletic Association Division I: 146, Division II: 41, Division III: 27, National Association of Intercollegiate Athletics: 8, and Junior College: 2. The majority (78%) of schools conducted the American Heart Association (AHA) 12-element history and physical examination. Division I institutions were more likely to add an ECG and/or echocardiogram (30%) to their preparticipation examination (PPE) compared with lower divisions (P < 0.0001). Those Division I schools using NICS were more likely to do so for all athletes (P < 0.001) or revenue generating sports (P < 0.001), whereas other institutions did so only for high-risk subgroups (P < 0.01). Lower division schools would consider adding ECG if it cost less (P = 0.01) or if there were more local expertise in athlete-specific interpretation standards (P = 0.04). Many National Collegiate Athletic Association Athletes Division I programs already use NICS to screen athletes, whereas a significant portion of lower division schools add ECG for athletes deemed high risk. Increased use of these modalities suggests limitations of traditional PPE screening methods. This is the first study to assess cardiac screening practices across all collegiate divisions and broadens our understanding of cardiac screening in high-level athletes.

  5. IDA 2004 Cost Research Symposium: Investments in, Use of, and Management of Cost Research

    DTIC Science & Technology

    2004-09-01

    Database: None Publication: Technical Report Keywords: Government, Aircraft, SD&D, Production, Integration, Data Collection, Database, CER B- 71 ... Martin Plant in Marietta , Georgia,” IDA Paper P-3590, July 2001 “Econometric Modeling of Acquisition Category I Systems at the Raytheon Plant in...NAVSEA) ............................................................ B- 71 Naval Surface Warfare Center, Dahlgren Division (NSWCDD

  6. 78 FR 72716 - Proposed Extension of the Information Collections Pertaining to Special Employment Under the Fair...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-03

    ... operations. See 29 CFR 530.101. Consistent with FLSA sections 11(d) and 14(c), the DOL's Wage and Hour... on the form. Frequency: On occasion. Total Burden Cost (capital/startup): $0. Total Burden Cost (operation/maintenance): $1,554. Dated: November 26, 2013. Mary Ziegler, Director, Division of Regulations...

  7. Electric power quarterly, July--September 1988

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1989-01-19

    The Electric Power Quarterly (EPQ) is prepared by the Electric Power Division; Office of Coal, Nuclear, Electric and Alternate Fuels; Energy Information Administration (EIA). The EPQ is designed to provide energy decisionmakers with accurate and timely generation and fuel cost and quality information on a plant-by-plant basis. This publication is designed for applications by electric utilities, fuel suppliers, consumers, educational institutions, and government in recognition of the importance of energy planning. The EPQ presents monthly summaries of electric utility statistics at the national, Census division, state, company, and plant levels on the following subjects: quantity of fuel; cost of fuel;more » quality of fuel; net generation; fuel consumption, and fuel stocks. In addition, the EPQ presents a quarterly summary of reported major disturbances and unusual occurrences. 1 fig., 15 tabs.« less

  8. Tunable optical frequency comb enabled scalable and cost-effective multiuser orthogonal frequency-division multiple access passive optical network with source-free optical network units.

    PubMed

    Chen, Chen; Zhang, Chongfu; Liu, Deming; Qiu, Kun; Liu, Shuang

    2012-10-01

    We propose and experimentally demonstrate a multiuser orthogonal frequency-division multiple access passive optical network (OFDMA-PON) with source-free optical network units (ONUs), enabled by tunable optical frequency comb generation technology. By cascading a phase modulator (PM) and an intensity modulator and dynamically controlling the peak-to-peak voltage of a PM driven signal, a tunable optical frequency comb source can be generated. It is utilized to assist the configuration of a multiple source-free ONUs enhanced OFDMA-PON where simultaneous and interference-free multiuser upstream transmission over a single wavelength can be efficiently supported. The proposed multiuser OFDMA-PON is scalable and cost effective, and its feasibility is successfully verified by experiment.

  9. Dynamic bandwidth allocation based on multiservice in software-defined wavelength-division multiplexing time-division multiplexing passive optical network

    NASA Astrophysics Data System (ADS)

    Wang, Fu; Liu, Bo; Zhang, Lijia; Jin, Feifei; Zhang, Qi; Tian, Qinghua; Tian, Feng; Rao, Lan; Xin, Xiangjun

    2017-03-01

    The wavelength-division multiplexing passive optical network (WDM-PON) is a potential technology to carry multiple services in an optical access network. However, it has the disadvantages of high cost and an immature technique for users. A software-defined WDM/time-division multiplexing PON was proposed to meet the requirements of high bandwidth, high performance, and multiple services. A reasonable and effective uplink dynamic bandwidth allocation algorithm was proposed. A controller with dynamic wavelength and slot assignment was introduced, and a different optical dynamic bandwidth management strategy was formulated flexibly for services of different priorities according to the network loading. The simulation compares the proposed algorithm with the interleaved polling with adaptive cycle time algorithm. The algorithm shows better performance in average delay, throughput, and bandwidth utilization. The results show that the delay is reduced to 62% and the throughput is improved by 35%.

  10. Cost-effectiveness of Haemophilus influenzae type b (Hib) vaccine introduction in the universal immunization schedule in Haryana State, India.

    PubMed

    Gupta, Madhu; Prinja, Shankar; Kumar, Rajesh; Kaur, Manmeet

    2013-01-01

    In India, Haemophilus influenzae type b (Hib) vaccine introduction in the universal immunization programme requires evidence of its potential health impact and cost-effectiveness, as it is a costly vaccine. Since childhood mortality, vaccination coverage and health service utilization vary across states, the cost-effectiveness of introducing Hib vaccine was studied in Haryana state. A mathematical model was used to compare scenarios with and without Hib vaccination to estimate the cost-effectiveness of Hib vaccine in Haryana from 2010 to 2024. Demographic and National Family Health Surveys were used to estimate vaccination coverage and mortality rates among children under 5. Hib pneumonia, Hib meningitis and invasive Hib disease incidence were based on Indian studies. Vaccine and syringe prices of the UNICEF supply division were used. Cost-effectiveness from government and societal perspectives was calculated as the net incremental cost per unit of health benefit gained [disability-adjusted life years (DALYs) averted, life years saved, Hib cases averted, Hib deaths averted]. Sensitivity analysis was done using variation in parameter estimates among different states of India. The incremental cost of Hib vaccine introduction from a government and a societal perspective was estimated to be US$81.4 and US$27.5 million, respectively, from 2010 to 2024. Vaccination of 73.3, 71.6 and 67.4 million children with first, second and third dose of pentavalent vaccine, respectively, would avert 7 067 817 cases, 31 331 deaths and 994 564 DALYs. Incremental cost per DALY averted from a government (US$819) and a societal perspective (US$277) was found to be less than the per capita gross national income of India in 2009. In sensitivity analysis, Hib vaccine introduction remained cost-effective for India. Hib vaccine introduction is a cost-effective strategy in India.

  11. Design and implementation of a Windows NT network to support CNC activities

    NASA Technical Reports Server (NTRS)

    Shearrow, C. A.

    1996-01-01

    The Manufacturing, Materials, & Processes Technology Division is undergoing dramatic changes to bring it's manufacturing practices current with today's technological revolution. The Division is developing Computer Automated Design and Computer Automated Manufacturing (CAD/CAM) abilities. The development of resource tracking is underway in the form of an accounting software package called Infisy. These two efforts will bring the division into the 1980's in relationship to manufacturing processes. Computer Integrated Manufacturing (CIM) is the final phase of change to be implemented. This document is a qualitative study and application of a CIM application capable of finishing the changes necessary to bring the manufacturing practices into the 1990's. The documentation provided in this qualitative research effort includes discovery of the current status of manufacturing in the Manufacturing, Materials, & Processes Technology Division including the software, hardware, network and mode of operation. The proposed direction of research included a network design, computers to be used, software to be used, machine to computer connections, estimate a timeline for implementation, and a cost estimate. Recommendation for the division's improvement include action to be taken, software to utilize, and computer configurations.

  12. Attention and implicit memory: priming-induced benefits and costs have distinct attentional requirements.

    PubMed

    Keane, Margaret M; Cruz, Matt E; Verfaellie, Mieke

    2015-02-01

    Attention at encoding plays a critical and ubiquitous role in explicit memory performance, but its role in implicit memory performance (i.e., priming) is more variable: some, but not all, priming effects are reduced by division of attention at encoding. A wealth of empirical and theoretical work has aimed to define the critical features of priming effects that do or do not require attention at encoding. This work, however, has focused exclusively on priming effects that are beneficial in nature (wherein performance is enhanced by prior exposure to task stimuli), and has overlooked priming effects that are costly in nature (wherein performance is harmed by prior exposure to task stimuli). The present study takes up this question by examining the effect of divided attention on priming-induced costs and benefits in a speeded picture-naming task. Experiment 1 shows that the costs, but not the benefits, are eliminated by division of attention at encoding. Experiment 2 shows that the costs (as well as the benefits) in this task are intact in amnesic participants, demonstrating that the elimination of the cost in the divided attention condition in Experiment 1 was not an artifact of the reduced availability of explicit memory in that condition. We suggest that the differential role of attention in priming-induced performance costs and benefits is linked to differences in response competition associated with these effects. This interpretation situates the present findings within a theoretical framework that has been applied to a broad range of facilitatory priming effects.

  13. New indicators based on personnel cost for management efficiency in a hospital.

    PubMed

    Nakagawa, Yoshiaki; Yoshihara, Hiroyuki; Nakagawa, Yoshinobu

    2011-08-01

    A simple and fair benchmarking system or financial indicators for use on the clinical department level have been lacking to evaluate the management efficiency and activity of each clinical department or division of a hospital. New financial indicators have therefore been developed based on personnel costs. Indicator 1: The ratio of marginal profit after personnel cost per personnel cost (RMP). Indicator 2: The ratio of investment (=indirect cost) per personnel cost (RIP). The difference between RMP and RIP demonstrates the operation profit in US Dollars for personnel cost (OPP). A turning point in profitability similar to the break-even point (BEP) and break-even ratio (BER) could be also defined by the combination of the RMP and RIP. The merits of these two indicators are not only the ability to indicate the relationship between the medical profit and the investments in the hospital, but also the capability to demonstrate such indicators as BEP, BER and OPP on a single graph. The two indicators were applied to the hospitals in the National Hospital Organization and to the clinical department in one hospital. Using these two indicators, it was possible to evaluate the management efficiency and medical activity not only in the whole hospital but also in each department and DPC/DRG group. This will be of use to a manager of a hospital in checking the management efficiency of his/her hospital despite the variations among hospitals, departments and divisions.

  14. 77 FR 12448 - Airworthiness Directives; Pratt & Whitney Division Turbofan Engines

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-01

    ... Delta Airlines, Inc. requested that we specify replacing affected FMUs with FMU P/N 53U044, or later FAA... actual cost of the AD; not other costs. We did not change the AD. Request To Replace FMUs On-Wing United Parcel Service Co. requested that we include in the AD the option to perform on-wing replacements of...

  15. 43 CFR 414.6 - Environmental compliance and funding of Federal costs.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... RECLAMATION, DEPARTMENT OF THE INTERIOR OFFSTREAM STORAGE OF COLORADO RIVER WATER AND DEVELOPMENT AND RELEASE OF INTENTIONALLY CREATED UNUSED APPORTIONMENT IN THE LOWER DIVISION STATES Water Quality and...

  16. 43 CFR 414.6 - Environmental compliance and funding of Federal costs.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... RECLAMATION, DEPARTMENT OF THE INTERIOR OFFSTREAM STORAGE OF COLORADO RIVER WATER AND DEVELOPMENT AND RELEASE OF INTENTIONALLY CREATED UNUSED APPORTIONMENT IN THE LOWER DIVISION STATES Water Quality and...

  17. 7 CFR 2003.26 - Functional organization of RBS.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... on cooperative marketing. The division conducts research and analysis and gives technical assistance... cooperative resource management. The division conducts research and analysis and gives technical assistance to... service to cooperative associations by administering a program of research and analysis of economic...

  18. Assessment of public vs private MSW management: a case study.

    PubMed

    Massoud, M A; El-Fadel, M; Abdel Malak, A

    2003-09-01

    Public-private partnerships in urban environmental services have witnessed increased interest in recent years primarily to reform the weak performance of the public sector, reduce cost, improve efficiency, and ensure environmental protection. In this context, successful public-private partnerships require a thorough analysis of opportunities, a deliberate attention to process details, and a continuous examination of services to determine whether they are more effectively performed by the private sector. A comparative assessment of municipal solid waste collection services in the two largest cities in Lebanon where until recently municipal solid waste collection is private in one and public in the other is conducted. While quality of municipal solid waste collection improved, due to private sector participation, the corresponding cost did not, due to monopoly and an inadequate organizational plan defining a proper division of responsibilities between the private and the public sector.

  19. Health promotion in supplementary health care: outsourcing, microregulation and implications for care.

    PubMed

    Silva, Kênia Lara; Sena, Roseni Rosângela; Rodrigues, Andreza Trevenzoli; Araújo, Fernanda Lopes; Belga, Stephanie Marques Moura Franco; Duarte, Elysângela Dittz

    2015-01-01

    to analyze health promotion programs in the supplementary health care. This was a multiple case study with a qualitative approach whose data were obtained from interviews with coordinators of providers contracted by the corporations of health insurance plans in Belo Horizonte, Minas Gerais. The data were submitted to Critical Discourse Analysis. Home care has been described as the main action in the field of health promotion transferred to the providers, followed by management of patients and cases, and the health education.groups. The existence of health promotion principles is questionable in all programs. Outsourcing is marked by a process with a division between cost and care management. Implications of this process occur within admission and interventions on the needs of the beneficiaries. Statements revealed rationalization of cost, restructuring of work, and reproduction of the dominant logic of capital accumulation by the health insurance companies.

  20. 75 FR 55527 - Proposed Flood Elevation Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-13

    ..., identified by Docket No. FEMA-B-1136, to Roy E. Wright, Deputy Director, Risk Analysis Division, Federal.... Wright, Deputy Director, Risk Analysis Division, Federal Insurance and Mitigation Administration, Federal....S.C. 601- 612, a regulatory flexibility analysis is not required. Executive Order 12866, Regulatory...

  1. Mobil`s Energy Management Program

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Schoeneborn, F.C.

    1997-06-01

    Mobil`s Facilities Management Network sponsored a cross-divisional team to reduce energy costs. This team developed an Energy Management Plan to reduce energy costs by $25 million annually throughout all Mobil divisions over the next five years (total of $125 million committed savings). The core of this plan is the belief that energy costs are controllable and should be managed with the expertise that Mobil manages other parts of the business. Areas of focus are economic procurement, efficient consumption, and expertise sharing.

  2. United States Army Annual Financial Statement FY00. The Army in Transformation Responsive to the Needs of the Nation

    DTIC Science & Technology

    2000-01-01

    continuing cost-cutting measures. Improvements have included establishing clearer customer-provider relationships, adopting private market mechanisms...measured by dividing these costs by gross wholesale sales. In FY 2000, the wholesale division achieved a $1.007 unit cost goal ( UCG ). Target UCG was...0.99. The over-execution of the UCG was due to higher than expected credit. Credit was over plan as a result of the Retail activities turning in more

  3. Turbine Manufacture

    NASA Technical Reports Server (NTRS)

    1979-01-01

    The machinery pictured is a set of Turbodyne steam turbines which power a sugar mill at Bell Glade, Florida. A NASA-developed computer program called NASTRAN aided development of these and other turbines manufactured by Turbodyne Corporation's Steam Turbine Division, Wellsville, New York. An acronym for NASA Structural Analysis Program, NASTRAN is a predictive tool which advises development teams how a structural design will perform under service use conditions. Turbodyne uses NASTRAN to analyze the dynamic behavior of steam turbine components, achieving substantial savings in development costs. One of the most widely used spinoffs, NASTRAN is made available to private industry through NASA's Computer Software Management Information Center (COSMIC) at the University of Georgia.

  4. Optimizing MRI Logistics: Focused Process Improvements Can Increase Throughput in an Academic Radiology Department.

    PubMed

    O'Brien, Jeremy J; Stormann, Jeremy; Roche, Kelli; Cabral-Goncalves, Ines; Monks, Annamarie; Hallett, Donna; Mortele, Koenraad J

    2017-02-01

    The purpose of this study was to describe and evaluate the effect of focused process improvements on protocol selection and scheduling in the MRI division of a busy academic medical center, as measured by examination and room times, magnet fill rate, and potential revenue increases and cost savings to the department. Focused process improvements, led by a multidisciplinary team at a large academic medical center, were directed at streamlining MRI protocols and optimizing matching protocol ordering to scheduling while maintaining or improving image quality. Data were collected before (June 2013) and after (March 2015) implementation of focused process improvements and divided by subspecialty on type of examination, allotted examination time, actual examination time, and MRI parameters. Direct and indirect costs were compiled and analyzed in consultation with the business department. Data were compared with evaluated effects on selected outcome and efficiency measures, as well as revenue and cost considerations. Statistical analysis was performed using a t test. During the month of June 2013, 2145 MRI examinations were performed at our center; 2702 were performed in March 2015. Neuroradiology examinations were the most common (59% in June 2013, 56% in March 2015), followed by body examinations (25% and 27%). All protocols and parameters were analyzed and streamlined for each examination, with slice thickness, TR, and echo train length among the most adjusted parameters. Mean time per examination decreased from 43.4 minutes to 36.7 minutes, and mean room time per patient decreased from 46.3 to 43.6 minutes (p = 0.009). Potential revenue from increased throughput may yield up to $3 million yearly (at $800 net revenue per scan) or produce cost savings if the facility can reduce staffed scanner hours or the number of scanners in its fleet. Actual revenue and expense impacts depend on the facility's fixed and variable cost structure, payer contracts, MRI fleet composition, and unmet MRI demand. Focused process improvements in selecting MRI protocols and scheduling examinations significantly increased throughput in the MRI division, thereby increasing capacity and revenue. Shorter scan and department times may also improve patient experience.

  5. Impact Properties of Metal Fan Containment Materials Being Evaluated for the High-Speed Civil Transport (HSCT)

    NASA Technical Reports Server (NTRS)

    1996-01-01

    Under the Enabling Propulsion Materials (EPM) program - a partnership between NASA, Pratt & Whitney, and GE Aircraft Engines - the Materials and Structures Divisions of the NASA Lewis Research Center are involved in developing a fan-containment system for the High-Speed Civil Transport (HSCT). The program calls for a baseline system to be designed by the end of 1995, with subsequent testing of innovative concepts. Five metal candidate materials are currently being evaluated for the baseline system in the Structures Division's Ballistic Impact Facility. This facility was developed to provide the EPM program with cost-efficient and timely impact test data. At the facility, material specimens are impacted at speeds up to 350 m/sec by projectiles of various sizes and shapes to assess the specimens' ability to absorb energy and withstand impact. The tests can be conducted at either room or elevated temperatures. Posttest metallographic analysis is conducted to improve understanding of the failure modes. A dynamic finite element program is used to simulate the events and both guide the testing as well as aid in designing the fan-containment system.

  6. New Whole-House Solutions Case Study: HVAC Design Strategy for a Hot-Humid Production Builder, Houston, Texas

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    None

    Building Science Corporation (BSC) worked directly with the David Weekley Homes - Houston division to develop a cost-effective design for moving the HVAC system into conditioned space. In addition, BSC conducted energy analysis to calculate the most economical strategy for increasing the energy performance of future production houses in preparation for the upcoming code changes in 2015. The following research questions were addressed by this research project: 1. What is the most cost effective, best performing and most easily replicable method of locating ducts inside conditioned space for a hot-humid production home builder that constructs one and two story singlemore » family detached residences? 2. What is a cost effective and practical method of achieving 50% source energy savings vs. the 2006 International Energy Conservation Code for a hot-humid production builder? 3. How accurate are the pre-construction whole house cost estimates compared to confirmed post construction actual cost? BSC and the builder developed a duct design strategy that employs a system of dropped ceilings and attic coffers for moving the ductwork from the vented attic to conditioned space. The furnace has been moved to either a mechanical closet in the conditioned living space or a coffered space in the attic.« less

  7. SEL's Software Process-Improvement Program

    NASA Technical Reports Server (NTRS)

    Basili, Victor; Zelkowitz, Marvin; McGarry, Frank; Page, Jerry; Waligora, Sharon; Pajerski, Rose

    1995-01-01

    The goals and operations of the Software Engineering Laboratory (SEL) is reviewed. For nearly 20 years the SEL has worked to understand, assess, and improve software and the development process within the production environment of the Flight Dynamics Division (FDD) of NASA's Goddard Space Flight Center. The SEL was established in 1976 with the goals of reducing: (1) the defect rate of delivered software, (2) the cost of software to support flight projects, and (3) the average time to produce mission-support software. After studying over 125 projects of FDD, the results have guided the standards, management practices, technologies, and the training within the division. The results of the studies have been a 75 percent reduction in defects, a 50 percent reduction in cost, and a 25 percent reduction in development time. Over time the goals of SEL have been clarified. The goals are now stated as: (1) Understand baseline processes and product characteristics, (2) Assess improvements that have been incorporated into the development projects, (3) Package and infuse improvements into the standard SEL process. The SEL improvement goal is to demonstrate continual improvement of the software process by carrying out analysis, measurement and feedback to projects with in the FDD environment. The SEL supports the understanding of the process by study of several processes including, the effort distribution, and error detection rates. The SEL assesses and refines the processes. Once the assessment and refinement of a process is completed, the SEL packages the process by capturing the process in standards, tools and training.

  8. Calibration and Validation of the COCOMO II.1997.0 Cost/Schedule Estimating Model to the Space and Missile Systems Center Database

    DTIC Science & Technology

    1997-09-01

    Daly chose five models (REVIC, PRICE-S, SEER, System-4, and SPQR /20) to estimate schedule for 21 separate projects from the Electronic System Division...PRICE-S, two variants of COCOMO, System-3, SPQR /20, SASET, SoftCost-Ada) to 11 eight Ada specific programs. Ada was specifically designed for and is

  9. 75 FR 34448 - Proposed CERCLA Administrative Cost Recovery Settlement; Great Lakes Container Corporation...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-17

    ... Cyanamid Company); Hubbard Hall, Inc.; Invesys, Inc. on behalf of Elmwood Sensors, Inc.; Chevron..., subsidiaries and divisions; BP Products North America, Inc.; Eastern Color & Chemical Company. Dated: June 3...

  10. Hybrid WDM/OCDMA for next generation access network

    NASA Astrophysics Data System (ADS)

    Wang, Xu; Wada, Naoya; Miyazaki, T.; Cincotti, G.; Kitayama, Ken-ichi

    2007-11-01

    Hybrid wavelength division multiplexing/optical code division multiple access (WDM/OCDMA) passive optical network (PON), where asynchronous OCDMA traffic transmits over WDM network, can be one potential candidate for gigabit-symmetric fiber-to-the-home (FTTH) services. In a cost-effective WDM/OCDMA network, a large scale multi-port encoder/decoder can be employed in the central office, and a low cost encoder/decoder will be used in optical network unit (ONU). The WDM/OCDMA system could be one promising solution to the symmetric high capacity access network with high spectral efficiency, cost effective, good flexibility and enhanced security. Asynchronous WDM/OCDMA systems have been experimentally demonstrated using superstructured fiber Bragg gratings (SSFBG) and muti-port OCDMA en/decoders. The total throughput has reached above Tera-bit/s with spectral efficiency of about 0.41. The key enabling techniques include ultra-long SSFBG, multi-port E/D with high power contrast ratio, optical thresholding, differential phase shift keying modulation with balanced detection, forward error correction, and etc. Using multi-level modulation formats to carry multi-bit information with single pulse, the total capacity and spectral efficiency could be further enhanced.

  11. Load management as a smart grid concept for sizing and designing of hybrid renewable energy systems

    NASA Astrophysics Data System (ADS)

    Eltamaly, Ali M.; Mohamed, Mohamed A.; Al-Saud, M. S.; Alolah, Abdulrahman I.

    2017-10-01

    Optimal sizing of hybrid renewable energy systems (HRES) to satisfy load requirements with the highest reliability and lowest cost is a crucial step in building HRESs to supply electricity to remote areas. Applying smart grid concepts such as load management can reduce the size of HRES components and reduce the cost of generated energy considerably. In this article, sizing of HRES is carried out by dividing the load into high- and low-priority parts. The proposed system is formed by a photovoltaic array, wind turbines, batteries, fuel cells and a diesel generator as a back-up energy source. A smart particle swarm optimization (PSO) algorithm using MATLAB is introduced to determine the optimal size of the HRES. The simulation was carried out with and without division of the load to compare these concepts. HOMER software was also used to simulate the proposed system without dividing the loads to verify the results obtained from the proposed PSO algorithm. The results show that the percentage of division of the load is inversely proportional to the cost of the generated energy.

  12. Economic evaluation of neonatal care packages in a cluster-randomized controlled trial in Sylhet, Bangladesh.

    PubMed

    LeFevre, Amnesty E; Shillcutt, Samuel D; Waters, Hugh R; Haider, Sabbir; El Arifeen, Shams; Mannan, Ishtiaq; Seraji, Habibur R; Shah, Rasheduzzaman; Darmstadt, Gary L; Wall, Steve N; Williams, Emma K; Black, Robert E; Santosham, Mathuram; Baqui, Abdullah H

    2013-10-01

    To evaluate and compare the cost-effectiveness of two strategies for neonatal care in Sylhet division, Bangladesh. In a cluster-randomized controlled trial, two strategies for neonatal care--known as home care and community care--were compared with existing services. For each study arm, economic costs were estimated from a societal perspective, inclusive of programme costs, provider costs and household out-of-pocket payments on care-seeking. Neonatal mortality in each study arm was determined through household surveys. The incremental cost-effectiveness of each strategy--compared with that of the pre-existing levels of maternal and neonatal care--was then estimated. The levels of uncertainty in our estimates were quantified through probabilistic sensitivity analysis. The incremental programme costs of implementing the home-care package were 2939 (95% confidence interval, CI: 1833-7616) United States dollars (US$) per neonatal death averted and US$ 103.49 (95% CI: 64.72-265.93) per disability-adjusted life year (DALY) averted. The corresponding total societal costs were US$ 2971 (95% CI: 1844-7628) and US$ 104.62 (95% CI: 65.15-266.60), respectively. The home-care package was cost-effective--with 95% certainty--if healthy life years were valued above US$ 214 per DALY averted. In contrast, implementation of the community-care strategy led to no reduction in neonatal mortality and did not appear to be cost-effective. The home-care package represents a highly cost-effective intervention strategy that should be considered for replication and scale-up in Bangladesh and similar settings elsewhere.

  13. Strategic planning for neuroradiologists.

    PubMed

    Berlin, Jonathan W; Lexa, Frank J

    2012-08-01

    Strategic planning is becoming essential to neuroradiology as the health care environment continues to emphasize cost efficiency, teamwork and collaboration. A strategic plan begins with a mission statement and vision of where the neuroradiology division would like to be in the near future. Formalized strategic planning frameworks, such as the strengths, weaknesses, opportunities and threats (SWOT), and the Balanced Scorecard frameworks, can help neuroradiology divisions determine their current position in the marketplace. Communication, delegation, and accountability in neuroradiology is essential in executing an effective strategic plan. Copyright © 2012 Elsevier Inc. All rights reserved.

  14. Cost Model/Data Base Catalog Non-DoD/Academic Survey. Volume 1. Project Summary

    DTIC Science & Technology

    1988-10-30

    presented in two volumes: Volume 1- Project Summary, and L .JD Volume 2- Final Data Base. J Accesion - For NTIS C R A& Disiji( .. . U, L)~ .6I...218 47I I I I I I I I Exhibit 111-3. COMPLETE CATALOG BREAKOUT I MANAGEMENT CONSULTING & RESEARCH, INC. j 111-6 I IE-I Iu 0 HE-4 X C.) E- Ix UI.n 111...College/EDCCAir University Maxwell Air Force Base, AL 36112 2. AD (Armament Division) Department of the Air Force Armament Division/(subdiv code

  15. Integrated cladding-pumped multicore few-mode erbium-doped fibre amplifier for space-division-multiplexed communications

    NASA Astrophysics Data System (ADS)

    Chen, H.; Jin, C.; Huang, B.; Fontaine, N. K.; Ryf, R.; Shang, K.; Grégoire, N.; Morency, S.; Essiambre, R.-J.; Li, G.; Messaddeq, Y.; Larochelle, S.

    2016-08-01

    Space-division multiplexing (SDM), whereby multiple spatial channels in multimode and multicore optical fibres are used to increase the total transmission capacity per fibre, is being investigated to avert a data capacity crunch and reduce the cost per transmitted bit. With the number of channels employed in SDM transmission experiments continuing to rise, there is a requirement for integrated SDM components that are scalable. Here, we demonstrate a cladding-pumped SDM erbium-doped fibre amplifier (EDFA) that consists of six uncoupled multimode erbium-doped cores. Each core supports three spatial modes, which enables the EDFA to amplify a total of 18 spatial channels (six cores × three modes) simultaneously with a single pump diode and a complexity similar to a single-mode EDFA. The amplifier delivers >20 dBm total output power per core and <7 dB noise figure over the C-band. This cladding-pumped EDFA enables combined space-division and wavelength-division multiplexed transmission over multiple multimode fibre spans.

  16. Integration of both dense wavelength-division multiplexing and coarse wavelength-division multiplexing demultiplexer on one photonic crystal chip

    NASA Astrophysics Data System (ADS)

    Tian, Huiping; Shen, Guansheng; Liu, Weijia; Ji, Yuefeng

    2013-07-01

    An integrated model of photonic crystal (PC) demultiplexer that can be used to combine dense wavelength-division multiplexing (DWDM) and coarse wavelength-division multiplexing (CWDM) systems is first proposed. By applying the PC demultiplexer, dense channel spacing 0.8 nm and coarse channel spacing 20 nm are obtained at the same time. The transmission can be improved to nearly 90%, and the crosstalk can be decreased to less than -18 dB by enlarging the width of the bus waveguide. The total size of the device is 21×42 μm2. Four channels on one side of the demultiplexer can achieve DWDM in the wavelength range between 1575 and 1578 nm, and the other four channels on the other side can achieve CWDM in the wavelength range between 1490 and 1565 nm, respectively. The demonstrated demultiplexer can be applied in the future CWDM and DWDM system, and the architecture costs can be significantly reduced.

  17. Economic costs of hospitalized diarrheal disease in Bangladesh: a societal perspective.

    PubMed

    Sarker, Abdur Razzaque; Sultana, Marufa; Mahumud, Rashidul Alam; Ali, Nausad; Huda, Tanvir M; Salim Uzzaman, M; Haider, Sabbir; Rahman, Hafizur; Islam, Ziaul; Khan, Jahangir A M; Van Der Meer, Robert; Morton, Alec

    2018-01-01

    Diarrheal diseases are a major threat to human health and still represent a leading cause of morbidity and mortality worldwide. Although the burden of the diarrheal diseases is much lower in developed countries, it is a significant public health problem in low and middle-income countries like Bangladesh. Though diarrhea is preventable and managed with low-cost interventions, it is still the leading cause of morbidity according to the patient who sought care from public hospitals in Bangladesh indicating that significant resources are consumed in treating those patients. The aim of the study is to capture the inpatients and outpatient treatment cost of diarrheal disease and to measure the cost burden and coping mechanisms associated with diarrheal illness. This study was conducted in six randomly selected district hospitals from six divisions (larger administrative units) in Bangladesh. The study was performed from the societal perspective which means all types of costs were identified, measured and valued no matter who incurred them. Cost analysis was estimated using the guideline proposed by the World Health Organization for estimating the economic burden of diarrheal diseases. The study adopted quantitative techniques to collect the household and hospital level data including structured and semi-structured questionnaires, observation checklists, analysis of hospital database, telephone interviews and compilation of service statistics. The average total societal cost of illness per episode was BDT 5274.02 (US $ 67.18) whereas the average inpatient and outpatient costs were BDT 8675.09 (US $ 110.51) and BDT 1853.96 (US $ 23.62) respectively. The cost burden was significantly highest for poorest households, 21.45% of household income, compared to 4.21% of the richest quintile. Diarrheal diseases continue to be an overwhelming problem in Bangladesh. The economic impact of any public health interventions (either preventive or promotive) that can reduce the prevalence of diarrheal diseases can be estimated from the data generated from this study.

  18. Direct and Lead Units in Execution of Battle (Battlefield Function 20) as Accomplished by a Heavy Brigade; Volume 1: Function Analysis.

    DTIC Science & Technology

    1998-01-01

    right of the division. e) Missions of other units with a significant bearing on the division. 3) Attachments and detachments. 5-1 Key Inputs and...g) Missions of units to the immediate left and right of the division. h) Missions of other units with a significant bearing on the...other units with a significant bearing on the division. 3) Attachments and detachments. c. MISSION d. EXECUTION Intent of the division commander

  19. Attention and Implicit Memory: Priming-Induced Benefits and Costs Have Distinct Attentional Requirements

    PubMed Central

    Keane, Margaret M.; Cruz, Matt E.; Verfaellie, Mieke

    2014-01-01

    Attention at encoding plays a critical and ubiquitous role in explicit memory performance, but its role in implicit memory performance (i.e., priming) is more variable: Some, but not all, priming effects are reduced by division of attention at encoding. A wealth of empirical and theoretical work has aimed to define the critical features of priming effects that do or do not require attention at encoding. This work, however, has focused exclusively on priming effects that are beneficial in nature (wherein performance is enhanced by prior exposure to task stimuli), and has overlooked priming effects that are costly in nature (wherein performance is harmed by prior exposure to task stimuli). The present study takes up this question by examining the effect of divided attention on priming-induced costs and benefits in a speeded picture-naming task. Experiment 1 shows that the costs, but not the benefits, are eliminated by division of attention at encoding. Experiment 2 shows that the costs (as well as the benefits) in this task are intact in amnesic participants, demonstrating that the elimination of the cost in the divided attention condition in Experiment 1 was not an artifact of the reduced availability of explicit memory in that condition. We suggest that the differential role of attention in priming-induced performance costs and benefits is linked to differences in response competition associated with these effects. This interpretation situates the present findings within a theoretical framework that has been applied to a broad range of facilitatory priming effects. PMID:25257650

  20. Impact of Transport Zone Number in Simulation Models on Cost-Benefit Analysis Results in Transport Investments

    NASA Astrophysics Data System (ADS)

    Chmielewski, Jacek

    2017-10-01

    Nowadays, feasibility studies need to be prepared for all planned transport investments, mainly those co-financed with UE grants. One of the fundamental aspect of feasibility study is the economic justification of an investment, evaluated in an area of so called cost-benefit analysis (CBA). The main goal of CBA calculation is to prove that a transport investment is really important for the society and should be implemented as economically efficient one. It can be said that the number of hours (PH - passengers hours) in trips and travelled kilometres (PK - passengers kilometres) are the most important for CBA results. The differences between PH and PK calculated for particular investment scenarios are the base for benefits calculation. Typically, transport simulation models are the best source for such data. Transport simulation models are one of the most powerful tools for transport network planning. They make it possible to evaluate forecast traffic volume and passenger flows in a public transport system for defined scenarios of transport and area development. There are many different transport models. Their construction is often similar, and they mainly differ in the level of their accuracy. Even models for the same area may differ in this matter. Typically, such differences come from the accuracy of supply side representation: road and public transport network representation. In many cases only main roads and a public transport network are represented, while local and service roads are eliminated as a way of reality simplification. This also enables a faster and more effective calculation process. On the other hand, the description of demand part of these models based on transport zones is often stable. Difficulties with data collection, mainly data on land use, resulted in the lack of changes in the analysed land division into so called transport zones. In this paper the author presents an influence of land division on the results of traffic analyses, and hence on CBA outcome. Moreover, the paper shows that the effectiveness of investments as represented in the results of cost-benefit analyses is strictly correlated to a transport model detail.

  1. 23 CFR 635.106 - Use of publicly owned equipment.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... agency for highway construction purposes may be warranted or justified. A proposal by any STD for the use... be performed on an actual cost basis, the STD shall submit to the Division Administrator for approval...

  2. 23 CFR 635.106 - Use of publicly owned equipment.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... agency for highway construction purposes may be warranted or justified. A proposal by any STD for the use... be performed on an actual cost basis, the STD shall submit to the Division Administrator for approval...

  3. 23 CFR 635.106 - Use of publicly owned equipment.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... agency for highway construction purposes may be warranted or justified. A proposal by any STD for the use... be performed on an actual cost basis, the STD shall submit to the Division Administrator for approval...

  4. 23 CFR 635.106 - Use of publicly owned equipment.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... agency for highway construction purposes may be warranted or justified. A proposal by any STD for the use... be performed on an actual cost basis, the STD shall submit to the Division Administrator for approval...

  5. Electric Power Monthly

    EIA Publications

    2017-01-01

    Provides monthly statistics at the state, Census division, and U.S. levels for net generation, fossil fuel consumption and stocks, quantity and quality of fossil fuels, cost of fossil fuels, electricity sales, revenue, and average revenue per kilowatthour of electricity sold.

  6. Cost-effective data collection to support INDOT's mission.

    DOT National Transportation Integrated Search

    2012-12-01

    This study's main purpose was to provide an inventory of the data collection programs undertaken by INDOT's divisions and offices and : to give recommendations regarding addition, removal, or modification of data collection programs. Chapter 1 provid...

  7. Overview of Engineering Design and Analysis at the NASA John C. Stennis Space Center

    NASA Technical Reports Server (NTRS)

    Congiardo, Jared; Junell, Justin; Kirkpatrick, Richard; Ryan, Harry

    2007-01-01

    This viewgraph presentation gives a general overview of the design and analysis division of NASA John C. Stennis Space Center. This division develops and maintains propulsion test systems and facilities for engineering competencies.

  8. Comparison of methods for estimating the cost of human immunodeficiency virus-testing interventions.

    PubMed

    Shrestha, Ram K; Sansom, Stephanie L; Farnham, Paul G

    2012-01-01

    The Centers for Disease Control and Prevention (CDC), Division of HIV/AIDS Prevention, spends approximately 50% of its $325 million annual human immunodeficiency virus (HIV) prevention funds for HIV-testing services. An accurate estimate of the costs of HIV testing in various settings is essential for efficient allocation of HIV prevention resources. To assess the costs of HIV-testing interventions using different costing methods. We used the microcosting-direct measurement method to assess the costs of HIV-testing interventions in nonclinical settings, and we compared these results with those from 3 other costing methods: microcosting-staff allocation, where the labor cost was derived from the proportion of each staff person's time allocated to HIV testing interventions; gross costing, where the New York State Medicaid payment for HIV testing was used to estimate program costs, and program budget, where the program cost was assumed to be the total funding provided by Centers for Disease Control and Prevention. Total program cost, cost per person tested, and cost per person notified of new HIV diagnosis. The median costs per person notified of a new HIV diagnosis were $12 475, $15 018, $2697, and $20 144 based on microcosting-direct measurement, microcosting-staff allocation, gross costing, and program budget methods, respectively. Compared with the microcosting-direct measurement method, the cost was 78% lower with gross costing, and 20% and 61% higher using the microcosting-staff allocation and program budget methods, respectively. Our analysis showed that HIV-testing program cost estimates vary widely by costing methods. However, the choice of a particular costing method may depend on the research question being addressed. Although program budget and gross-costing methods may be attractive because of their simplicity, only the microcosting-direct measurement method can identify important determinants of the program costs and provide guidance to improve efficiency.

  9. Low Cost Technical Solutions to Jump Start an Insider Threat Program

    DTIC Science & Technology

    2016-05-11

    Low Cost Technical Solutions to Jump Start an Insider Threat Program George J. Silowash Derrick L. Spooner Daniel L. Costa Michael J...Albrethsen May 2016 TECHNICAL NOTE CMU/SEI-2016-TN-004 CERT Division http://www.sei.cmu.edu Copyright 2016 Carnegie Mellon University This... technical note will explore tools that may be suitable for satisfying the basic technical needs of an insider threat program, giving organizations a

  10. Bolstering Skin Grafts With a Surgical Scrub Brush: A Cost-effective Solution.

    PubMed

    Buller, Mitchell; Lee, Thomas J; Davis, Jared; Wilhelmi, Bradon J

    2017-01-01

    Objective: The objective of this article is to review the methods currently used for the bolstering of skin grafts and compare their advantages and disadvantages with those of the dry, sterile surgical scrub brush. We report a series of cases performed at a single institution and compare the cost-effectiveness, application, and limitations of this method with other options for skin graft bolstering. Methods: A PubMed search using the parameters "(bolster) AND skin graft" was conducted, yielding 85 results. A total of 40 publications met the criteria for our literature review. The costs of the foam bolsters utilized as stents for skin grafts were obtained from the Central Supply and Resource Division of the University of Louisville Hospital for a cost analysis. The cost per square centimeter of each bolster material was calculated. Results: At $0.003/cm 2 , the 3M Reston foam is the most inexpensive of the 3 bolster materials analyzed. The dry, sterile surgical scrub brush has a similar cost at $0.006/cm 2 but carries the advantage of sterility. The material cost of negative pressure wound therapy is $0.47/cm 2 , and the cost of the system as a whole makes it a much more expensive alternative. In 6 patients with defects of varying size and location, the scrub brush bolster showed a near 100% graft take and no complications. Conclusions: The dry, sterile surgical scrub brush presents a readily available and low-cost option for the stenting of small skin grafts and should be considered a viable method in the armamentarium of available skin graft bolsters.

  11. Optimization of sparse synthetic transmit aperture imaging with coded excitation and frequency division.

    PubMed

    Behar, Vera; Adam, Dan

    2005-12-01

    An effective aperture approach is used for optimization of a sparse synthetic transmit aperture (STA) imaging system with coded excitation and frequency division. A new two-stage algorithm is proposed for optimization of both the positions of the transmit elements and the weights of the receive elements. In order to increase the signal-to-noise ratio in a synthetic aperture system, temporal encoding of the excitation signals is employed. When comparing the excitation by linear frequency modulation (LFM) signals and phase shift key modulation (PSKM) signals, the analysis shows that chirps are better for excitation, since at the output of a compression filter the sidelobes generated are much smaller than those produced by the binary PSKM signals. Here, an implementation of a fast STA imaging is studied by spatial encoding with frequency division of the LFM signals. The proposed system employs a 64-element array with only four active elements used during transmit. The two-dimensional point spread function (PSF) produced by such a sparse STA system is compared to the PSF produced by an equivalent phased array system, using the Field II simulation program. The analysis demonstrates the superiority of the new sparse STA imaging system while using coded excitation and frequency division. Compared to a conventional phased array imaging system, this system acquires images of equivalent quality 60 times faster, when the transmit elements are fired in pairs consecutively and the power level used during transmit is very low. The fastest acquisition time is achieved when all transmit elements are fired simultaneously, which improves detectability, but at the cost of a slight degradation of the axial resolution. In real-time implementation, however, it must be borne in mind that the frame rate of a STA imaging system depends not only on the acquisition time of the data but also on the processing time needed for image reconstruction. Comparing to phased array imaging, a significant increase in the frame rate of a STA imaging system is possible if and only if an equivalent time efficient algorithm is used for image reconstruction.

  12. A single-cell pedigree analysis of alternative stochastic lymphocyte fates

    PubMed Central

    Hawkins, E. D.; Markham, J. F.; McGuinness, L. P.; Hodgkin, P. D.

    2009-01-01

    In contrast to most stimulated lymphocytes, B cells exposed to Toll-like receptor 9 ligands are nonself-adherent, allowing individual cells and families to be followed in vitro for up to 5 days. These B cells undergo phases typical of an adaptive response, dividing up to 6 times before losing the impetus for further growth and division and eventually dying by apoptosis. Using long-term microscopic imaging, accurate histories of individual lymphocyte fates were collected. Quantitative analysis of family relationships revealed that times to divide of siblings were strongly related but these correlations were progressively lost through consecutive divisions. A weaker, but significant, correlation was also found for death times among siblings. Division cessation is characterized by a loss of cell growth and the division in which this occurs is strongly inherited from the original founder cell and is related to the size this cell reaches before its first division. Thus, simple division-based dilution of factors synthesized during the first division may control the maximum division reached by stimulated cells. The stochastic distributions of times to divide, times to die, and divisions reached are also measured. Together, these results highlight the internal cellular mechanisms that control immune responses and provide a foundation for the development of new mathematical models that are correct at both single-cell and population levels. PMID:19633185

  13. Full duplex dense-wavelength-division-multiplexing radio-over-fiber system transmission of 75-GHz W-band frequency multiple-input multiple-output orthogonal-frequency-division-multiplexing signals with 3×12 Gbps downstream and 6 Gbps upstream

    NASA Astrophysics Data System (ADS)

    Fang, Wei Jin; Huang, Xu Guang; Yang, Kai; Zhang, Xiao Min

    2012-09-01

    We propose and demonstrate a full duplex dense-wavelength-division-multiplexing radio-over-fiber (DWDM-ROF) system for transmitting 75-GHz W-band frequency multiple-input multiple-output orthogonal-frequency-division-multiplexing (MIMO-OFDM) signals with 12 Gbps downstream and 6 Gbps upstream. The downstream transmitting terminal is based on a three-channels sextupling-frequency scheme using an external modulation of a distributed feedback laser diode (DFB-LD) and dual drive Mach-Zehnder modulator (DD-MZM) for carrying downstream signals. MIMO-OFDM algorithms effectively compensate for impairments in the wireless link. Without using costly W-band components in the transmitter, a 12 Gbps downstream transmission system operation at 75 GHz is experimentally validated. For the downstream transmission, a power penalty of less than 3 dB was observed after a 50 km single mode fiber (SMF) and 4 m wireless transmission at a bit error rate (BER) of 3.8×10-3. For the upstream transmission, we use a commercially available 1.5 GHz bandwidth reflective semiconductor optical amplifier (RSOA) to achieve 6 Gbps upstream traffic for 16 QAM-OFDM signals. A power penalty of 3 dB was observed after a 50 km SMF transmission at a BER of 3.8×10-3. The frequency of the local oscillator is reduced due to the frequency sextupling scheme. The cost of the proposed system is largely reduced.

  14. Low-cost coherent receiver for long-reach optical access network using single-ended detection.

    PubMed

    Zhang, Xuebing; Li, Zhaohui; Li, Jianping; Yu, Changyuan; Lau, Alan Pak Tao; Lu, Chao

    2014-09-15

    A low-cost coherent receiver using two 2×3 optical hybrids and single-ended detection is proposed for long-reach optical access network. This structure can detect the two polarization components of polarization division multiplexing (PDM) signals. Polarization de-multiplexing and signal-to-signal beat interference (SSBI) cancellation are realized by using only three photodiodes. Simulation results for 40 Gb/s PDM-OFDM transmissions indicate that the low-cost coherent receiver has 3.2 dB optical signal-to-noise ratio difference compared with the theoretical value.

  15. 1990 National Water Quality Laboratory Services Catalog

    USGS Publications Warehouse

    Pritt, Jeffrey; Jones, Berwyn E.

    1989-01-01

    PREFACE This catalog provides information about analytical services available from the National Water Quality Laboratory (NWQL) to support programs of the Water Resources Division of the U.S. Geological Survey. To assist personnel in the selection of analytical services, the catalog lists cost, sample volume, applicable concentration range, detection level, precision of analysis, and preservation techniques for samples to be submitted for analysis. Prices for services reflect operationa1 costs, the complexity of each analytical procedure, and the costs to ensure analytical quality control. The catalog consists of five parts. Part 1 is a glossary of terminology; Part 2 lists the bottles, containers, solutions, and other materials that are available through the NWQL; Part 3 describes the field processing of samples to be submitted for analysis; Part 4 describes analytical services that are available; and Part 5 contains indices of analytical methodology and Chemical Abstract Services (CAS) numbers. Nomenclature used in the catalog is consistent with WATSTORE and STORET. The user is provided with laboratory codes and schedules that consist of groupings of parameters which are measured together in the NWQL. In cases where more than one analytical range is offered for a single element or compound, different laboratory codes are given. Book 5 of the series 'Techniques of Water Resources Investigations of the U.S. Geological Survey' should be consulted for more information about the analytical procedures included in the tabulations. This catalog supersedes U.S. Geological Survey Open-File Report 86-232 '1986-87-88 National Water Quality Laboratory Services Catalog', October 1985.

  16. Analysis of Whiskey by Dispersive Liquid-Liquid Microextraction Coupled with Gas Chromatography/Mass Spectrometry: An Upper Division Analytical Chemistry Experiment Guided by Green Chemistry

    ERIC Educational Resources Information Center

    Owens, Janel E.; Zimmerman, Laura B.; Gardner, Michael A.; Lowe, Luis E.

    2016-01-01

    Analysis of whiskey samples prepared by a green microextraction technique, dispersive liquid-liquid microextraction (DLLME), before analysis by a qualitative gas chromatography-mass spectrometry (GC/MS) method, is described as a laboratory experiment for an upper division instrumental methods of analysis laboratory course. Here, aroma compounds in…

  17. Non-consent towing cost study in Utah.

    DOT National Transportation Integrated Search

    2015-01-01

    This study was conducted on behalf of the UDOT Motor Carrier Division at the request of the towing industry in : Utah to evaluate the maximum allowable rates for Non-Consent Towing. The objectives were to: 1-Evaluate : the Current Maximum...

  18. Geologic Materials Center - General Information | Alaska Division of

    Science.gov Websites

    effective November 9, 2017. Set by DGGS Director's Order, the fees will help offset operational costs and -effective alternative to the tremendous expense of core drilling and resampling in the field. One foot of

  19. BIOVENTING DEVELOPMENT PROGRAM (TREATMENT AND DESTRUCTION BRANCH, LRPCD, NRMRL)

    EPA Science Inventory

    In a continuing effort to develop environment-friendly and cost-effective remediation technologies, the Land Remediation and Pollution Control Division (LRPCD) conducts an aggressive research and development program in bioventing. LRPCD's bioventing program is multi-faceted, with...

  20. 28 CFR 63.6 - Procedures.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Administration DEPARTMENT OF JUSTICE (CONTINUED) FLOODPLAIN MANAGEMENT AND WETLAND PROTECTION PROCEDURES § 63.6... Resources Division, or by law. For certain actions, notice may entail other audiences and means of..., etc.); economic aspects (costs of space, construction, services, and relocation); and legal...

  1. 28 CFR 63.6 - Procedures.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Administration DEPARTMENT OF JUSTICE (CONTINUED) FLOODPLAIN MANAGEMENT AND WETLAND PROTECTION PROCEDURES § 63.6... Resources Division, or by law. For certain actions, notice may entail other audiences and means of..., etc.); economic aspects (costs of space, construction, services, and relocation); and legal...

  2. Engineering Cyanobacterial Cell Morphology for Enhanced Recovery and Processing of Biomass.

    PubMed

    Jordan, Adam; Chandler, Jenna; MacCready, Joshua S; Huang, Jingcheng; Osteryoung, Katherine W; Ducat, Daniel C

    2017-05-01

    Cyanobacteria are emerging as alternative crop species for the production of fuels, chemicals, and biomass. Yet, the success of these microbes depends on the development of cost-effective technologies that permit scaled cultivation and cell harvesting. Here, we investigate the feasibility of engineering cell morphology to improve biomass recovery and decrease energetic costs associated with lysing cyanobacterial cells. Specifically, we modify the levels of Min system proteins in Synechococcus elongatus PCC 7942. The Min system has established functions in controlling cell division by regulating the assembly of FtsZ, a tubulin-like protein required for defining the bacterial division plane. We show that altering the expression of two FtsZ-regulatory proteins, MinC and Cdv3, enables control over cell morphology by disrupting FtsZ localization and cell division without preventing continued cell growth. By varying the expression of these proteins, we can tune the lengths of cyanobacterial cells across a broad dynamic range, anywhere from an ∼20% increased length (relative to the wild type) to near-millimeter lengths. Highly elongated cells exhibit increased rates of sedimentation under low centrifugal forces or by gravity-assisted settling. Furthermore, hyperelongated cells are also more susceptible to lysis through the application of mild physical stress. Collectively, these results demonstrate a novel approach toward decreasing harvesting and processing costs associated with mass cyanobacterial cultivation by altering morphology at the cellular level. IMPORTANCE We show that the cell length of a model cyanobacterial species can be programmed by rationally manipulating the expression of protein factors that suppress cell division. In some instances, we can increase the size of these cells to near-millimeter lengths with this approach. The resulting elongated cells have favorable properties with regard to cell harvesting and lysis. Furthermore, cells treated in this manner continue to grow rapidly at time scales similar to those of uninduced controls. To our knowledge, this is the first reported example of engineering the cell morphology of cyanobacteria or algae to make them more compatible with downstream processing steps that present economic barriers to their use as alternative crop species. Therefore, our results are a promising proof-of-principle for the use of morphology engineering to increase the cost-effectiveness of the mass cultivation of cyanobacteria for various sustainability initiatives. Copyright © 2017 American Society for Microbiology.

  3. Cost effectiveness analysis of the New Jersey rapid testing algorithm for HIV testing in publicly funded testing sites.

    PubMed

    Stevinson, Kendall; Martin, Eugene G; Marcella, Stephen; Paul, Sindy M

    2011-12-01

    Before 2009, New Jersey (NJ) publicly funded counseling and testing sites (CTS) tested for HIV using a single rapid test followed, when positive, by a Western Blot (WB) for confirmation. With this strategy, 74.8% of confirmed positive clients returned to receive test results. To improve the client notification rate at these centers, the New Jersey (NJ) Division of HIV, STD and TB Services (DHSTS) implemented a rapid testing algorithm (RTA) which utilizes a second, different, rapid test to verify a preliminary positive. To compare the cost-effectiveness of the two testing algorithms. This was a retrospective cost-effectiveness analysis. New Jersey HIV Rapid Testing Support Program (NJHIV) records, DHSTS grant documents, counseling time estimates from an online survey of site supervisors. Costs included test kits and personnel costs from month of RTA implementation through 11/30 in 2008 and 2009. The incremental cost of the RTA was calculated per additional percent of positive clients who were notified and per day earlier notification. In 2008, 215 of 247 clients with a positive rapid HIV test were confirmed positive by WB. 90.9% of clients were notified a mean of 11.4 days after their initial test. 12 refused confirmatory WB. In 2009, 152 of 170 clients with one positive rapid test had a confirmatory second positive rapid test and were notified on the same day. The incremental cost of the RTA was $20.31 per additional positive person notified and $24.31 per day earlier notification or $3.23 per additional positive person and $3.87 per day earlier notification if the WB were eliminated. The RTA is a cost-effective strategy achieving 100% notification of newly HIV positive clients a mean of 11.4 days earlier compared to standard testing. Copyright © 2011 Elsevier B.V. All rights reserved.

  4. A cost effectiveness study of integrated care in health services delivery: a diabetes program in Australia

    PubMed Central

    McRae, Ian S; Butler, James RG; Sibthorpe, Beverly M; Ruscoe, Warwick; Snow, Jill; Rubiano, Dhigna; Gardner, Karen L

    2008-01-01

    Background Type 2 diabetes is rapidly growing as a proportion of the disease burden in Australia as elsewhere. This study addresses the cost effectiveness of an integrated approach to assisting general practitioners (GPs) with diabetes management. This approach uses a centralized database of clinical data of an Australian Division of General Practice (a network of GPs) to co-ordinate care according to national guidelines. Methods Long term outcomes for patients in the program were derived using clinical parameters after 5 years of program participation, and the United Kingdom Prospective Diabetes Study (UKPDS) Outcomes Model, to project outcomes for 40 years from the time of diagnosis and from 5 years post-diagnosis. Cost information was obtained from a range of sources. While program costs are directly available, and costs of complications can be estimated from the UKPDS model, other costs are estimated by comparing costs in the Division with average costs across the state or the nation. The outcome and cost measures are used derive incremental cost-effectiveness ratios. Results The clinical data show that the program is effective in the short term, with improvement or no statistical difference in most clinical measures over 5 years. Average HbA1c levels increased by less than expected over the 5 year period. While the program is estimated to generate treatment cost savings, overall net costs are positive. However, the program led to projected improvements in expected life years and Quality Adjusted Life Expectancy (QALE), with incremental cost effectiveness ratios of $A8,106 per life-year saved and $A9,730 per year of QALE gained. Conclusions The combination of an established model of diabetes progression and generally available data has provided an opportunity to establish robust methods of testing the cost effectiveness of a program for which a formal control group was not available. Based on this methodology, integrated health care delivery provided by a network of GPs improved health outcomes of type 2 diabetics with acceptable cost effectiveness, which suggests that similar outcomes may be obtained elsewhere. PMID:18834551

  5. The Energy - Water Connection: Can We Sustain Critical Resources and Make them Reliable, Affordable, and Environmentally Sound?(LBNL Summer Lecture Series)

    ScienceCinema

    McMahon, Jim

    2018-05-16

    Summer Lecture Series 2006: Jim McMahon of Berkeley Lab's Environmental Energy Technologies Division (EETD) is head of the Energy Analysis Department in EETD, which provides technical analysis to the Department of Energy on things like energy efficiency appliance standards. McMahon and his colleagues helped the nation save tens of billions of dollars in energy costs since the standards program began. Now his Water-Energy Technology Team (WETT) is applying its expertise to the linked problem of energy and water. Each of us requires more than 500 gallons per person per day for food production, plus an additional 465 gallons to produce household electricity. WETT hopes to mine some of the numerous opportunities to save energy and water by applying new technologies.

  6. Instrumentation and Controls Division progress report for the period July 1, 1986 to June 30, 1988

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Klobe, L.E.

    1988-12-01

    The Instrumentation and Controls (IandC) Division of Oak Ridge National Laboratory (ORNL) performs basic and applied instrumentation and controls research, development and design engineering, specialized instrument design and fabrication, and maintenance services for instruments, electronics, and computers. The IandC Division is one of the largest RandD organizations of its type among government laboratories, and it exists as the result of an organizational strategy to integrate ORNL's instrumentation and controls-related disciplines into one dedicated functional organization to increase the Laboratory's expertise and capabilities in these rapidly expanding, innovative areas of technology. The Division participates in the programs and projects of ORNLmore » by applying its expertise and capabilities in concert with other divisions to perform basic research and mission-oriented technology development. Many of the Division's RandD tasks that are a part of a larger ORNL program are of sufficient scope that the IandC effort constitutes a separate program element with direct funding and management responsibility within the Division. The activities of IandC include performance of an RandD task in IandC facilities, the participation of from one of many IandC engineers and scientists in a multidisciplinary team working in a specific research area or development project, design and fabrication of a special instrument or instrumentation system, or a few hours of maintenance service. In its support and maintenance work, the role of the IandC Division is to provide a level of expertise appropriate to complete a job successfully at minimum overall cost and time schedule---a role which involves IandC in almost all ORNL activities.« less

  7. Methods for geochemical analysis

    USGS Publications Warehouse

    Baedecker, Philip A.

    1987-01-01

    The laboratories for analytical chemistry within the Geologic Division of the U.S. Geological Survey are administered by the Office of Mineral Resources. The laboratory analysts provide analytical support to those programs of the Geologic Division that require chemical information and conduct basic research in analytical and geochemical areas vital to the furtherance of Division program goals. Laboratories for research and geochemical analysis are maintained at the three major centers in Reston, Virginia, Denver, Colorado, and Menlo Park, California. The Division has an expertise in a broad spectrum of analytical techniques, and the analytical research is designed to advance the state of the art of existing techniques and to develop new methods of analysis in response to special problems in geochemical analysis. The geochemical research and analytical results are applied to the solution of fundamental geochemical problems relating to the origin of mineral deposits and fossil fuels, as well as to studies relating to the distribution of elements in varied geologic systems, the mechanisms by which they are transported, and their impact on the environment.

  8. A guide to unclassified sensitive information protection

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Donahue, S.C.

    1996-11-14

    This document is a reference guide for CIC-Division employees who lead or participate in projects that use and/or produce unclassified sensitive information. It is intended for use on a case by case basis to develop project specific sensitive information handling procedures and standards. It contains criteria for identifying sensitive information and determining levels of sensitivity, and describes cost effective measures for protecting various levels of sensitive information. The goal of this document is to help establish good business practices that benefit both the Laboratory and its customers. Division personnel are encouraged to apply these guidelines.

  9. Evaluation of costs to process and manage utility and driveway permits.

    DOT National Transportation Integrated Search

    2014-10-01

    Reviewing and processing utility and driveway permits at the Texas Department of Transportation (TxDOT) : requires a considerable amount of involvement and coordination by TxDOT personnel, both at the district : and division levels. Currently, TxDOT ...

  10. CONTRACT ADMINISTRATIVE TRACKING SYSTEM (CATS)

    EPA Science Inventory

    The Contract Administrative Tracking System (CATS) was developed in response to an ORD NHEERL, Mid-Continent Ecology Division (MED)-recognized need for an automated tracking and retrieval system for Cost Reimbursable Level of Effort (CR/LOE) Contracts. CATS is an Oracle-based app...

  11. 48 CFR 2942.101 - Policy.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 7 2010-10-01 2010-10-01 false Policy. 2942.101 Section 2942.101 Federal Acquisition Regulations System DEPARTMENT OF LABOR CONTRACT MANAGEMENT CONTRACT ADMINISTRATION AND AUDIT SERVICES Contract Audit Services 2942.101 Policy. The OASAM Division of Cost...

  12. Statement of Robert F. Hale, Assistant Director, National Security Division, Congressional Budget Office

    DTIC Science & Technology

    1987-03-17

    rates also have some potential disadvantages . Key among them are higher near-term program costs. These costs would probably require offsetting budget...HIGHER PRODUCTION RATES Should DoD produce weapons at higher rates? Certain disadvantages must be weighed against the merits of higher rates... Disadvantages of Higher Production Rates The most imporant disadvantage of higher production rates is the delay or cancellation of new weapons systems that

  13. High Head Unshrouded Impeller Pump Stage Technology

    NASA Technical Reports Server (NTRS)

    Williams, Robert W.; Skelley, Stephen E.; Stewart, Eric T.; Droege, Alan R.; Prueger, George H.; Chen, Wei-Chung; Williams, Morgan; Turner, James E. (Technical Monitor)

    2000-01-01

    A team of engineers at NASA/MSFC and Boeing, Rocketdyne division, are developing unshrouded impeller technologies that will increase payload and decrease cost of future reusable launch vehicles. Using the latest analytical techniques and experimental data, a two-stage unshrouded fuel pump is being designed that will meet the performance requirements of a three-stage shrouded pump. Benefits of the new pump include lower manufacturing costs, reduced weight, and increased payload to orbit.

  14. Economic evaluation of neonatal care packages in a cluster-randomized controlled trial in Sylhet, Bangladesh

    PubMed Central

    Shillcutt, Samuel D; Waters, Hugh R; Haider, Sabbir; El Arifeen, Shams; Mannan, Ishtiaq; Seraji, Habibur R; Shah, Rasheduzzaman; Darmstadt, Gary L; Wall, Steve N; Williams, Emma K; Black, Robert E; Santosham, Mathuram; Baqui, Abdullah H

    2013-01-01

    Abstract Objective To evaluate and compare the cost-effectiveness of two strategies for neonatal care in Sylhet division, Bangladesh. Methods In a cluster-randomized controlled trial, two strategies for neonatal care – known as home care and community care – were compared with existing services. For each study arm, economic costs were estimated from a societal perspective, inclusive of programme costs, provider costs and household out-of-pocket payments on care-seeking. Neonatal mortality in each study arm was determined through household surveys. The incremental cost-effectiveness of each strategy – compared with that of the pre-existing levels of maternal and neonatal care – was then estimated. The levels of uncertainty in our estimates were quantified through probabilistic sensitivity analysis. Findings The incremental programme costs of implementing the home-care package were 2939 (95% confidence interval, CI: 1833–7616) United States dollars (US$) per neonatal death averted and US$ 103.49 (95% CI: 64.72–265.93) per disability-adjusted life year (DALY) averted. The corresponding total societal costs were US$ 2971 (95% CI: 1844–7628) and US$ 104.62 (95% CI: 65.15–266.60), respectively. The home-care package was cost-effective – with 95% certainty – if healthy life years were valued above US$ 214 per DALY averted. In contrast, implementation of the community-care strategy led to no reduction in neonatal mortality and did not appear to be cost-effective. Conclusion The home-care package represents a highly cost-effective intervention strategy that should be considered for replication and scale-up in Bangladesh and similar settings elsewhere. PMID:24115797

  15. Mask strategy at International SEMATECH

    NASA Astrophysics Data System (ADS)

    Kimmel, Kurt R.

    2002-08-01

    International SEMATECH (ISMT) is a consortium consisting of 13 leading semiconductor manufacturers from around the globe. Its objective is to develop the infrastructure necessary for its member companies to realize the International Technology Roadmap for Semiconductors (ITRS) through efficiencies of shared development resources and knowledge. The largest area of effort is lithography, recognized as a crucial enabler for microelectronics technology progress. Within the Lithography Division, most of the efforts center on mask-related issues. The development strategy at International SEMATCH will be presented and the interlock of lithography projects clarified. Because of the limited size of the mask production equipment market, the business case is weak for aggressive investment commensurate with the pace of the International Technology Roadmap for Semiconductors. With masks becoming the overwhelming component of lithography cost, new ways of reducing or eliminating mask costs are being explored. Will mask technology survive without a strong business case? Will the mask industry limit the growth of the semiconductor industry? Are advanced masks worth their escalating cost? An analysis of mask cost from the perspective of mask value imparted to the user is presented with examples and generic formulas for the reader to apply independently. A key part to the success for both International SEMATECH and the industry globally will be partnerships on both the local level between mask-maker and mask-user, and the macro level where global collaborations will be necessary to resolve technology development cost challenges.

  16. The hidden cost of deep neck space infections

    PubMed

    Hurley, R H; Douglas, C M; Montgomery, J; Clark, L J

    2018-02-01

    Introduction The incidence of deep neck space infection (DNSI) is rising and appears to be related to falling rates of tonsillectomy. The purpose of this study was to assess demographics of patients presenting with DNSI and the financial burden to the National Health Service (NHS). Methods Data were collected retrospectively on patients aged over 16 years admitted to NHS Greater Glasgow and Clyde with DNSI between 2012 and 2016. Demographics, aetiology and use of hospital resources were reviewed. The cost of hospital admissions was calculated using data from NHS Scotland's Information Services Division, the local diagnostics division and the British National Formulary. Results Seventy-four patients were admitted with DNSI during the study period. Forty (54%) were male. The mean age was 44.0 years (range: 16-86 years). The most frequent source of infection was the tonsil (n=30, 40.5%). The most common infective organism was Streptococcus constellatus (n=9, 12.2%). The mean length of stay was 11 days. Fifty-five patients (74.3%) required operative intervention. The mean cost of admission per patient was £5,700 (range: £332-£46,700). Conclusions This study highlights the high cost burden of DNSI to the NHS. The incidence of DNSI in Glasgow has risen over the study period; contributing factors may include the reduced tonsillectomy rate and a reduction in antibiotic prescribing. As the incidence of DNSI continues to rise, there will be an increase in cost to the NHS, which must be planned for.

  17. Pre-Service Teachers' Flexibility with Referent Units in Solving a Fraction Division Problem

    ERIC Educational Resources Information Center

    Lee, Mi Yeon

    2017-01-01

    This study investigated 111 pre-service teachers' (PSTs') flexibility with referent units in solving a fraction division problem using a length model. Participants' written solutions to a measurement fraction division problem were analyzed in terms of strategies and types of errors, using an inductive content analysis approach. Findings suggest…

  18. Transportation of Hazardous Evidentiary Material.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Osborn, Douglas.

    2005-06-01

    This document describes the specimen and transportation containers currently available for use with hazardous and infectious materials. A detailed comparison of advantages, disadvantages, and costs of the different technologies is included. Short- and long-term recommendations are also provided.3 DraftDraftDraftExecutive SummaryThe Federal Bureau of Investigation's Hazardous Materials Response Unit currently has hazardous material transport containers for shipping 1-quart paint cans and small amounts of contaminated forensic evidence, but the containers may not be able to maintain their integrity under accident conditions or for some types of hazardous materials. This report provides guidance and recommendations on the availability of packages for themore » safe and secure transport of evidence consisting of or contaminated with hazardous chemicals or infectious materials. Only non-bulk containers were considered because these are appropriate for transport on small aircraft. This report will addresses packaging and transportation concerns for Hazardous Classes 3, 4, 5, 6, 8, and 9 materials. If the evidence is known or suspected of belonging to one of these Hazardous Classes, it must be packaged in accordance with the provisions of 49 CFR Part 173. The anthrax scare of several years ago, and less well publicized incidents involving unknown and uncharacterized substances, has required that suspicious substances be sent to appropriate analytical laboratories for analysis and characterization. Transportation of potentially hazardous or infectious material to an appropriate analytical laboratory requires transport containers that maintain both the biological and chemical integrity of the substance in question. As a rule, only relatively small quantities will be available for analysis. Appropriate transportation packaging is needed that will maintain the integrity of the substance, will not allow biological alteration, will not react chemically with the substance being shipped, and will otherwise maintain it as nearly as possible in its original condition.The recommendations provided are short-term solutions to the problems of shipping evidence, and have considered only currently commercially available containers. These containers may not be appropriate for all cases. Design, testing, and certification of new transportation containers would be necessary to provide a container appropriate for all cases.Table 1 provides a summary of the recommendations for each class of hazardous material.Table 1: Summary of RecommendationsContainerCost1-quart paint can with ArmlockTM seal ringLabelMaster(r)%242.90 eachHazard Class 3, 4, 5, 8, or 9 Small ContainersTC Hazardous Material Transport ContainerCurrently in Use4 DraftDraftDraftTable 1: Summary of Recommendations (continued)ContainerCost55-gallon open or closed-head steel drumsAll-Pak, Inc.%2458.28 - %2473.62 eachHazard Class 3, 4, 5, 8, or 9 Large Containers95-gallon poly overpack LabelMaster(r)%24194.50 each1-liter glass container with plastic coatingLabelMaster(r)%243.35 - %243.70 eachHazard Class 6 Division 6.1 Poisonous by Inhalation (PIH) Small ContainersTC Hazardous Material Transport ContainerCurrently in Use20 to 55-gallon PIH overpacksLabelMaster(r)%24142.50 - %24170.50 eachHazard Class 6 Division 6.1 Poisonous by Inhalation (PIH) Large Containers65 to 95-gallon poly overpacksLabelMaster(r)%24163.30 - %24194.50 each1-liter transparent containerCurrently in UseHazard Class 6 Division 6.2 Infectious Material Small ContainersInfectious Substance ShipperSource Packaging of NE, Inc.%24336.00 eachNone Commercially AvailableN/AHazard Class 6 Division 6.2 Infectious Material Large ContainersNone Commercially Available N/A5« less

  19. Accounting Information Systems in Healthcare: A Review of the Literature.

    PubMed

    Hammour, Hadal; Househ, Mowafa; Razzak, Hira Abdul

    2017-01-01

    As information technology progresses in Saudi Arabia, the manual accounting systems have become graduallyinadequate for decision needs. Subsequently, private and public healthcare divisions in Saudi Arabia perceive Computerized accounting information system (CAIS) as a vehicle to safeguard efficient and effective flow of information during the analysis, processes, and recording of financial data. Efficient and effective flow of information improvesthe decision making of staff, thereby improving the capability of health care sectors to reduce cost of the medical services.In this paper, we define computerized accounting systems from the point of view of health informatics. Also, the challenges and benefits of supporting CAIS applications in hospitals of Saudi Arabia. With these elements, we conclude that CAIS in Saudi Arabia can serve as a valuable tool for evaluating and controlling the cost of medical services in healthcare sectors. Supplementary education on the significance of having systems of computerized accounting within hospitals for nurses, doctors, and accountants with other health care staff is warranted in future.

  20. 2 CFR Appendix A to Part 230 - General Principles

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... subgrant or subcontract). Equipment, capital expenditures, charges for patient care, rental costs and the... care in connection with organizations or separate divisions thereof which receive the preponderance of... deviations from the established practices of the organization which may unjustifiably increase the award...

  1. 2 CFR Appendix A to Part 230 - General Principles

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... subgrant or subcontract). Equipment, capital expenditures, charges for patient care, rental costs and the... care in connection with organizations or separate divisions thereof which receive the preponderance of... deviations from the established practices of the organization which may unjustifiably increase the award...

  2. 2 CFR Appendix A to Part 230 - General Principles

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... subgrant or subcontract). Equipment, capital expenditures, charges for patient care, rental costs and the... care in connection with organizations or separate divisions thereof which receive the preponderance of... deviations from the established practices of the organization which may unjustifiably increase the award...

  3. 48 CFR 31.205-26 - Material costs.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... to the contract. If material is issued from stores, any generally recognized method of pricing such... for all materials, supplies and services that are sold or transferred between any divisions... established practice of the transferring organization to price interorganizational transfers at other than...

  4. 48 CFR 31.205-26 - Material costs.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... to the contract. If material is issued from stores, any generally recognized method of pricing such... for all materials, supplies and services that are sold or transferred between any divisions... established practice of the transferring organization to price interorganizational transfers at other than...

  5. The Cost-Effectiveness of Birth-Cohort Screening for Hepatitis C Antibody in U.S. Primary Care Settings

    PubMed Central

    Rein, David B.; Smith, Bryce D.; Wittenborn, John S.; Lesesne, Sarah B.; Wagner, Laura D.; Roblin, Douglas W.; Patel, Nita; Ward, John W.; Weinbaum, Cindy M.

    2017-01-01

    Background In the United States, hepatitis C virus (HCV) infection is most prevalent among adults born from 1945 through 1965, and approximately 50% to 75% of infected adults are unaware of their infection. Objective To estimate the cost-effectiveness of birth-cohort screening. Design Cost-effectiveness simulation. Data Sources National Health and Nutrition Examination Survey, U.S. Census, Medicare reimbursement schedule, and published sources. Target Population Adults born from 1945 through 1965 with 1 or more visits to a primary care provider annually. Time Horizon Lifetime. Perspective Societal, health care. Intervention One-time antibody test of 1945–1965 birth cohort. Outcome Measures Numbers of cases that were identified and treated and that achieved a sustained viral response; liver disease and death from HCV; medical and productivity costs; quality-adjusted life-years (QALYs); incremental cost-effectiveness ratio (ICER). Results of Base-Case Analysis Compared with the status quo, birth-cohort screening identified 808 580 additional cases of chronic HCV infection at a screening cost of $2874 per case identified. Assuming that birth-cohort screening was followed by pegylated interferon and ribavirin (PEG-IFN + R) for treated patients, screening increased QALYs by 348 800 and costs by $5.5 billion, for an ICER of $15 700 per QALY gained. Assuming that birth-cohort screening was followed by direct-acting antiviral plus PEG-IFN + R treatment for treated patients, screening increased QALYs by 532 200 and costs by $19.0 billion, for an ICER of $35 700 per QALY saved. Results of Sensitivity Analysis The ICER of birth-cohort screening was most sensitive to sustained viral response of antiviral therapy, the cost of therapy, the discount rate, and the QALY losses assigned to disease states. Limitation Empirical data on screening and direct-acting antiviral treatment in real-world clinical settings are scarce. Conclusion Birth-cohort screening for HCV in primary care settings was cost-effective. Primary Funding Source Division of Viral Hepatitis, Centers for Disease Control and Prevention. PMID:22056542

  6. Operationalising United Nations Security Council Resolution 1325 within the Australian Defence Force

    DTIC Science & Technology

    2016-01-01

    Hutchinson Joint & Operations Analysis Division Defence Science and Technology Group DST- Group -GD-0909 ABSTRACT This literature...LIMITATION UNCLASSIFIED UNCLASSIFIED Published by Joint & Operations Analysis Division Defence Science and Technology Group 506 Lorimer St...This page intentionally blank UNCLASSIFIED DST- Group -GD-0909 UNCLASSIFIED Contents 1. INTRODUCTION

  7. Publications - GMC 29 | Alaska Division of Geological & Geophysical Surveys

    Science.gov Websites

    DGGS GMC 29 Publication Details Title: Geochemical analysis (total organic carbon, rock-eval pyrolysis Reference Minder, Michael, and Shell Oil Company, 1985, Geochemical analysis (total organic carbon, rock ; Total Organic Carbon; Vitrinite Reflectance Top of Page Department of Natural Resources, Division of

  8. Publications - GMC 25 | Alaska Division of Geological & Geophysical Surveys

    Science.gov Websites

    DGGS GMC 25 Publication Details Title: Geochemical analysis (total organic carbon, rock-eval pyrolysis Reference Unknown, 1984, Geochemical analysis (total organic carbon, rock-eval pyrolysis, kerogen type ; Total Organic Carbon; Vitrinite Reflectance Top of Page Department of Natural Resources, Division of

  9. Publications - GMC 28 | Alaska Division of Geological & Geophysical Surveys

    Science.gov Websites

    DGGS GMC 28 Publication Details Title: Geochemical analysis (total organic carbon, rock-eval pyrolysis Reference Brown and Ruth Laboratories, Inc., 1985, Geochemical analysis (total organic carbon, rock-eval Organic Carbon Top of Page Department of Natural Resources, Division of Geological & Geophysical

  10. Chiral pathways in DNA dinucleotides using gradient optimized refinement along metastable borders

    NASA Astrophysics Data System (ADS)

    Romano, Pablo; Guenza, Marina

    We present a study of DNA breathing fluctuations using Markov state models (MSM) with our novel refinement procedure. MSM have become a favored method of building kinetic models, however their accuracy has always depended on using a significant number of microstates, making the method costly. We present a method which optimizes macrostates by refining borders with respect to the gradient along the free energy surface. As the separation between macrostates contains highest discretization errors, this method corrects for any errors produced by limited microstate sampling. Using our refined MSM methods, we investigate DNA breathing fluctuations, thermally induced conformational changes in native B-form DNA. Running several microsecond MD simulations of DNA dinucleotides of varying sequences, to include sequence and polarity effects, we've analyzed using our refined MSM to investigate conformational pathways inherent in the unstacking of DNA bases. Our kinetic analysis has shown preferential chirality in unstacking pathways that may be critical in how proteins interact with single stranded regions of DNA. These breathing dynamics can help elucidate the connection between conformational changes and key mechanisms within protein-DNA recognition. NSF Chemistry Division (Theoretical Chemistry), the Division of Physics (Condensed Matter: Material Theory), XSEDE.

  11. Reconfigurable WDM-PON empowered by a low-cost 8-channel directly modulated laser module

    NASA Astrophysics Data System (ADS)

    Zhang, Yi-ming; Liu, Yu; Zhang, Zhi-ke; Zhao, Ze-ping; Tian, Ye; Zhu, Ning-hua

    2017-11-01

    A 10 Gbit/s 16-km-long reconfigurable wavelength-division-multiplexing passive optical network (WDM-PON) is presented empowered by a low-cost multi-channel directly modulated laser (DML) module. Compared with the case using discrete devices in conventional scheme, the proposed DML module provides a cost-effective solution with reduced complexity. The clear eye diagram and the bit error rate ( BER) of less than 2×10-7 with a sensitivity of -7 dBm are obtained. Due to the special packaging design, the crosstalk between channels under condition of simultaneous operation can be negligible.

  12. Economic impact of providing workplace influenza vaccination. A model and case study application at a Brazilian pharma-chemical company.

    PubMed

    Burckel, E; Ashraf, T; de Sousa Filho, J P; Forleo Neto, E; Guarino, H; Yauti, C; Barreto F de, B; Champion, L

    1999-11-01

    To develop and apply a model to assess the economic value of a workplace influenza programme from the perspective of the employer. The model calculated the avoided costs of influenza, including treatment costs, lost productivity, lost worker added value and the cost of replacing workers. Subtracted from this benefit were the costs associated with a vaccination programme, including administrative costs, the time to give the vaccine, and lost productivity due to adverse reactions. The framework of the model can be applied to any company to estimate the cost-benefit of an influenza immunisation programme. The model developed was applied to 4030 workers in the core divisions of a Brazilian pharma-chemical company. The model determined a net benefit of $US121,441 [129,335 Brazilian reals ($Brz)], or $US35.45 ($Brz37.75) per vaccinated employee (1997 values). The cost-benefit ratio was 1:2.47. The calculations were subjected to a battery of 1-way and 2-way sensitivity analyses that determined that net benefit would be retained as long as the vaccine cost remained below $US45.40 ($Brz48.40) or the vaccine was at least 32.5% effective. Other alterations would retain a net benefit as well, including several combinations of incidence rate and vaccine effectiveness. The analysis suggests that providing an influenza vaccination programme can incur a substantial net benefit for an employer, although the size of the benefit will depend upon who normally absorbs the costs of treating influenza and compensating workers for lost work time due to illness, as well as the type of company in which the immunisation programme is applied.

  13. Roles, Cost, and Criteria for Assessing Agriculture Disaster Assistance Programs Between 1980 and 1988

    DTIC Science & Technology

    1990-03-06

    Deveopmer. Division vkef ore the Subca-rittee c:- Agr~cultural Productirm and Stablllza-t;cn of Prices Senate Ccrratt:ee on Agric -.;ture, \\,utr;.tion and...efficient program, costs [ 1Disaster Assistance: Crop Insurance Can Provide Assistance More Effectively Than Other Programs (GAO/RCED-89-211, Sept. 20...1989). 1ist * should be minimized. On this basis, we identified eight criteria that should be considered in devising an effective disaster assistance

  14. Neural basis of increased costly norm enforcement under adversity.

    PubMed

    Wu, Yan; Yu, Hongbo; Shen, Bo; Yu, Rongjun; Zhou, Zhiheng; Zhang, Guoping; Jiang, Yushi; Zhou, Xiaolin

    2014-12-01

    Humans are willing to punish norm violations even at a substantial personal cost. Using fMRI and a variant of the ultimatum game and functional magnetic resonance imaging, we investigated how the brain differentially responds to fairness in loss and gain domains. Participants (responders) received offers from anonymous partners indicating a division of an amount of monetary gain or loss. If they accept, both get their shares according to the division; if they reject, both get nothing or lose the entire stake. We used a computational model to derive perceived fairness of offers and participant-specific inequity aversion. Behaviorally, participants were more likely to reject unfair offers in the loss (vs gain) domain. Neurally, the positive correlation between fairness and activation in ventral striatum was reduced, whereas the negative correlations between fairness and activations in dorsolateral prefrontal cortex were enhanced in the loss domain. Moreover, rejection-related dorsal striatum activation was higher in the loss domain. Furthermore, the gain-loss domain modulates costly punishment only when unfair behavior was directed toward the participants and not when it was directed toward others. These findings provide neural and computational accounts of increased costly norm enforcement under adversity and advanced our understanding of the context-dependent nature of fairness preference. © The Author (2014). Published by Oxford University Press. For Permissions, please email: journals.permissions@oup.com.

  15. 128 Gb/s TWDM PON system using dispersion-supported transmission method

    NASA Astrophysics Data System (ADS)

    Bindhaiq, Salem; Zulkifli, Nadiatulhuda; Supa'at, Abusahmah M.; Idrus, Sevia M.; Salleh, M. S.

    2017-11-01

    Time and wavelength division multiplexed passive optical network (TWDM-PON) trend is considered as the most extraordinary trend of the next generation solution to accommodate exponential traffic growth for converged new services. In this paper, we briefly review recent progress on TWDM-PON system through the use of low cost directly modulated lasers (DMLs) transmission for various line rate transmissions to date. Furthermore, through simulation, we propose and evaluate a cost effective way to upgrade TWDM-PON up to a symmetric capacity of 128 Gb/s using fiber Bragg gratings (FBGs) in optical line terminal (OLT) as a paramount dispersion manager in high speed light-wave systems in both upstream and downstream directions. A low cost and potential chirpless directed modulated grating laser (DMGL) is employed for downstream link and DML with a single delay-interferometer (DI) is employed for upstream link. After illustrating the demonstrated system architecture and configuration, we present the results and analysis to prove the system feasibility. The results show that a successful transmission is achieved over 40 km single mode fiber with a power budget of 33.7 dB, which could support 1:256 splitting ratio.

  16. Composite Nozzle/Thrust Chambers Analyzed for Low-Cost Boosters

    NASA Technical Reports Server (NTRS)

    Sullivan, Roy M.

    1999-01-01

    The Low Cost Booster Technology Program is an initiative to minimize the cost of future liquid engines by using advanced materials and innovative designs, and by reducing engine complexity. NASA Marshall Space Flight Center s 60K FASTRAC Engine is one example where these design philosophies have been put into practice. This engine burns a liquid kerosene/oxygen mixture. It uses a one-piece, polymer composite thrust chamber/nozzle that is constructed of a tape-wrapped silica phenolic liner, a metallic injector interface ring, and a filament-wound epoxy overwrap. A cooperative effort between NASA Lewis Research Center s Structures Division and Marshall is underway to perform a finite element analysis of the FASTRAC chamber/nozzle under all the loading and environmental conditions that it will experience during its lifetime. The chamber/nozzle is a complex composite structure. Of its three different materials, the two composite components have distinctly different fiber architectures and, consequently, require separate material model descriptions. Since the liner is tape wrapped, it is orthotropic in the nozzle global coordinates; and since the overwrap is filament wound, it is treated as a monoclinic material. Furthermore, the wind angle on the overwrap varies continuously along the length of the chamber/nozzle.

  17. Publications - GMC 177 | Alaska Division of Geological & Geophysical

    Science.gov Websites

    and Facilities Staff Seismic and Well Data Data Reports Contact Us Frequently Asked Questions Ask a . Navy Umiat Test Well #11 Authors: Bujak Davies Group Publication Date: 1990 Publisher: Alaska Division , Palynological analysis of core (342.9'-1037') from the U.S. Navy Umiat Test Well #11: Alaska Division of

  18. 78 FR 19745 - Privacy Act of 1974; Privacy Act System of Records

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-02

    ... address, badge number, monthly commuting cost, email address, years of government service, grade, personal..., rideshare, or other transit program applications, status or participation reports of individuals... Subsidy Program Lead, Logistics Management Division, Location 4, as set forth in Appendix A. NOTIFICATION...

  19. Counterfire Requirements in an Insurgency

    DTIC Science & Technology

    2006-02-07

    2002): http://www.ausa.org/. 12 Larry Bovino and Mark Weber, “Lightweight Counter-Mortar Radar,” Radar and Combat ID Division, Intelligence...of the legacy radars at a fraction of the cost and improves the troop force protection in the process. 12 BIBLIOGRAPHY Bovino , Larry., and Mark

  20. Training Trainers on a Tight Budget.

    ERIC Educational Resources Information Center

    Schoonmaker, Robert L.

    1979-01-01

    Presents training budget ideas which meet these criteria: (1) minimal cost, (2) minimal time consumption, and (3) convey skill or concept. Ideas include learning from attendance at free training demonstrations, sales meetings, professional groups, college/university courses, staff and division trainer meetings, visitations, cotraining sessions,…

  1. 7 CFR 1710.300 - General.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... the forecast, including the methodology used to project loads, rates, revenue, power costs, operating expenses, plant additions, and other factors having a material effect on the balance sheet and on financial... regional office will consult with the Power Supply Division in the case of generation projects for...

  2. Report: Oregon Health Authority’s Prior Labor-Charging Practices Under EPA Grants Did Not Meet Requirements

    EPA Pesticide Factsheets

    Report #16-P-0313, September 12, 2016. The Oregon Health Authority's Public Health Division practice prior to May 2014 of charging labor hours based on budget allocations resulted in more than $12 million in unsupported costs.

  3. Bidirectional optical subassembly-shaped 20-Gbit/s compact single-mode four-channel wavelength-division multiplexing optical modules for optical multimedia interfaces

    NASA Astrophysics Data System (ADS)

    Lim, Kwon-Seob; Yu, Hong-Yeon; Park, Hyoung-Jun; Kang, Hyun Seo; Jang, Jae-Hyung

    2016-06-01

    Low-cost single-mode four-channel optical transmitter and receiver modules using the wavelength-division multiplexing (WDM) method have been developed for long-reach fiber optic applications. The single-mode four-channel WDM optical transmitter and receiver modules consist of two dual-wavelength optical transmitter and receiver submodules, respectively. The integration of two channels in a glass-sealed transistor outline-can package is an effective way to reduce cost and size and to extend the number of channels. The clear eye diagrams with more than about 6 dB of the extinction ratio and the minimum receiver sensitivity of lower than -16 dBm at a bit error rate of 10-12 have been obtained for the transmitter and receiver modules, respectively, at 5 Gbps/channel. The 4K ultrahigh definition contents have been transmitted over a 1-km-long single-mode fiber using a pair of proposed four-channel transmitter optical subassembly and receiver optical subassembly.

  4. Continuous Improvement in Battery Testing at the NASA/JSC Energy System Test Area

    NASA Technical Reports Server (NTRS)

    Boyd, William; Cook, Joseph

    2003-01-01

    The Energy Systems Test Area (ESTA) at the Lyndon B. Johnson Space Center in Houston, Texas conducts development and qualification tests to fulfill Energy System Division responsibilities relevant to ASA programs and projects. EST A has historically called upon a variety of fluid, mechanical, electrical, environmental, and data system capabilities spread amongst five full-service facilities to test human and human supported spacecraft in the areas of propulsion systems, fluid systems, pyrotechnics, power generation, and power distribution and control systems. Improvements at ESTA are being made in full earnest of offering NASA project offices an option to choose a thorough test regime that is balanced with cost and schedule constraints. In order to continue testing of enabling power-related technologies utilized by the Energy System Division, an especially proactive effort has been made to increase the cost effectiveness and schedule responsiveness for battery testing. This paper describes the continuous improvement in battery testing at the Energy Systems Test Area being made through consolidation, streamlining, and standardization.

  5. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    This eighth annual report of the Division covers work done during FY 1981 (October 1, 1980, through September 30, 1981). As with these documents in the past, the format follows approximately the organizational structure of the Energy Division. Chapters 2 through 6 summarize the activities of the sections of the Division: Environmental Impact Section, headed by H.E. Zittel; Regional and Urban Studies Section, R.M. Davis; Economic Analysis Section, R.B. Shelton; Data and Analysis Section, A.S. Loebl; and Efficiency and Renewables Research Section, J.W. Michel. In addition, work on a variety of projects which cut across section lines is reported inmore » Chapter 7, Integrated Programs. These activities are under the supervision of T.J. Wilbanks, Associate Director for the Division. Separate abstracts are included for individual projects.« less

  6. The evolution analysis of listed companies co-holding non-listed financial companies based on two-mode heterogeneous networks

    NASA Astrophysics Data System (ADS)

    An, Pengli; Li, Huajiao; Zhou, Jinsheng; Chen, Fan

    2017-10-01

    Complex network theory is a widely used tool in the empirical research of financial markets. Two-mode and multi-mode networks are new trends and represent new directions in that they can more accurately simulate relationships between entities. In this paper, we use data for Chinese listed companies holding non-listed financial companies over a ten-year period to construct two networks: a two-mode primitive network in which listed companies and non-listed financial companies are considered actors and events, respectively, and a one-mode network that is constructed based on the decreasing-mode method in which listed companies are considered nodes. We analyze the evolution of the listed company co-holding network from several perspectives, including that of the whole network, of information control ability, of implicit relationships, of community division and of small-world characteristics. The results of the analysis indicate that (1) China's developing stock market affects the share-holding condition of listed companies holding non-listed financial companies; (2) the information control ability of co-holding networks is focused on a few listed companies and the implicit relationship of investment preference between listed companies is determined by the co-holding behavior; (3) the community division of the co-holding network is increasingly obvious, as determined by the investment preferences among listed companies; and (4) the small-world characteristics of the co-holding network are increasingly obvious, resulting in reduced communication costs. In this paper, we conduct an evolution analysis and develop an understanding of the factors that influence the listed companies co-holding network. This study will help illuminate research on evolution analysis.

  7. Financing Losses from Catastrophic Risks

    DTIC Science & Technology

    2008-11-01

    University of Pennsylvania Smetters@wharton.upenn.edu David Torregrosa Macroeconomic Analysis Division Congressional Budget Office...Office, Macroeconomic Analysis Division,Second and D Streets SW,Washington,DC,20515-6925 8. PERFORMING ORGANIZATION REPORT NUMBER 9. SPONSORING...exceeds $40 trillion (Bank for International Settlements 2007), or over eighty times the capital reserves of the entire insurance industry worldwide

  8. An algol program for dissimilarity analysis: a divisive-omnithetic clustering technique

    USGS Publications Warehouse

    Tipper, J.C.

    1979-01-01

    Clustering techniques are used properly to generate hypotheses about patterns in data. Of the hierarchical techniques, those which are divisive and omnithetic possess many theoretically optimal properties. One such method, dissimilarity analysis, is implemented here in ALGOL 60, and determined to be competitive computationally with most other methods. ?? 1979.

  9. Polarity, cell division, and out-of-equilibrium dynamics control the growth of epithelial structures

    PubMed Central

    Cerruti, Benedetta; Puliafito, Alberto; Shewan, Annette M.; Yu, Wei; Combes, Alexander N.; Little, Melissa H.; Chianale, Federica; Primo, Luca; Serini, Guido; Mostov, Keith E.; Celani, Antonio

    2013-01-01

    The growth of a well-formed epithelial structure is governed by mechanical constraints, cellular apico-basal polarity, and spatially controlled cell division. Here we compared the predictions of a mathematical model of epithelial growth with the morphological analysis of 3D epithelial structures. In both in vitro cyst models and in developing epithelial structures in vivo, epithelial growth could take place close to or far from mechanical equilibrium, and was determined by the hierarchy of time-scales of cell division, cell–cell rearrangements, and lumen dynamics. Equilibrium properties could be inferred by the analysis of cell–cell contact topologies, and the nonequilibrium phenotype was altered by inhibiting ROCK activity. The occurrence of an aberrant multilumen phenotype was linked to fast nonequilibrium growth, even when geometric control of cell division was correctly enforced. We predicted and verified experimentally that slowing down cell division partially rescued a multilumen phenotype induced by altered polarity. These results improve our understanding of the development of epithelial organs and, ultimately, of carcinogenesis. PMID:24145168

  10. Structure-function analysis of the extracellular domain of the pneumococcal cell division site positioning protein MapZ

    NASA Astrophysics Data System (ADS)

    Manuse, Sylvie; Jean, Nicolas L.; Guinot, Mégane; Lavergne, Jean-Pierre; Laguri, Cédric; Bougault, Catherine M.; Vannieuwenhze, Michael S.; Grangeasse, Christophe; Simorre, Jean-Pierre

    2016-06-01

    Accurate placement of the bacterial division site is a prerequisite for the generation of two viable and identical daughter cells. In Streptococcus pneumoniae, the positive regulatory mechanism involving the membrane protein MapZ positions precisely the conserved cell division protein FtsZ at the cell centre. Here we characterize the structure of the extracellular domain of MapZ and show that it displays a bi-modular structure composed of two subdomains separated by a flexible serine-rich linker. We further demonstrate in vivo that the N-terminal subdomain serves as a pedestal for the C-terminal subdomain, which determines the ability of MapZ to mark the division site. The C-terminal subdomain displays a patch of conserved amino acids and we show that this patch defines a structural motif crucial for MapZ function. Altogether, this structure-function analysis of MapZ provides the first molecular characterization of a positive regulatory process of bacterial cell division.

  11. [Analysis of state costs of the social security benefits provided to the insured presenting with lung cancer and pulmonary diseases caused by external factors].

    PubMed

    Kuklińska-Janiak, Dorota

    2013-12-01

    Lung cancer and pneumoconioses constitute two serious problems of contemporary medicine and a public health system. To analyze the costs associated with social security benefits provided to the insured presenting with lung cancer and pulmonary diseases (including pneumoconioses) caused by external factors. The analysis was based on the data obtained from the Department of Statistics and Actuarial Forecasts of the Social Insurance Institution (SlI) in Warsaw. Structural diversity of the costs of the separate benefits available within the national health insurance system has been considered. Based on the data available in Poland costs associated with the incidence of lung cancer and pneumoconiosis were assessed taking into account sex and age of the insured as well as the administrative division of Poland. Additionally, mortality rates from the selected pulmonary diseases were analyzed. Costs of the pensions paid to the insured presenting with lung cancer amount to 81.11% of the total social security costs associated with these diseases, while the sick leave money paid to the insured lung cancer patients equal to 15.5% of the total costs. In the insured women, costs of the pensions paid due to occupational pulmonary diseases (predominantly pneumoconioses) constitute 41.1% and in the insured men--11.5% of the total 'occupational' pensions. Although the maximal incidence of lung cancer occurs in both men and women above their retirement ages the costs of the work incapacity pensions paid to lung cancer patients still exceed 81% of the total social security costs associated with these diseases. In the insured women, the cost of pensions paid due to occupational pulmonary diseases, most of which are pneumoconioses, ranks first among the costs of 'occupational' pensions received by these subjects, while in the insured men the respective cost ranks third (after injuries plus intoxications and cardiovascular diseases) among their 'occupational' pensions. Moreover, the results of the performed analyses indicate that data on the social insurance money allow to comprehensively evaluate the health status of the insured men and women as well as their quality of life and therapeutical, rehabilitational and prophylactic needs. These data can and should, therefore, be utilized in both clinical practice and for accomplishment of the public health tasks.

  12. Design of Standards and Labeling programs in Chile: Techno-Economic Analysis for Refrigerators

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Letschert, Virginie E.; McNeil, Michael A.; Pavon, Mariana

    2013-05-01

    Lawrence Berkeley National Laboratory is a global leader in the study of energy efficiency and its effective implementation through government policy. The Energy Analysis and Environmental Impacts Department of LBNL’s Environmental Energy Technologies Division provides technical assistance to help federal, stat e and local government agencies in the United States, and throughout the world, develop long-term strategies, policy, and programs to encourage energy efficiency in all sectors and industries. In the past, LBNL has assisted staff of various countries government agencies and their con tractors in providing methodologies to analyze cost-effectiveness of regulations and asses s overall national impacts ofmore » efficiency programs. The paper presents the work done in collaboration with the Ministry of Energy (MoE) in Chile and the Collaborative Labeling Appliance Standards Programs (CLASP) on designing a Minimum Energy Performance Standards (MEPS) and ext ending the current labeling program for refrigerators.« less

  13. Estimating the incidence, prevalence and true cost of asthma in the UK: secondary analysis of national stand-alone and linked databases in England, Northern Ireland, Scotland and Wales—a study protocol

    PubMed Central

    Mukherjee, Mome; Gupta, Ramyani; Farr, Angela; Heaven, Martin; Stoddart, Andrew; Nwaru, Bright I; Fitzsimmons, Deborah; Chamberlain, George; Bandyopadhyay, Amrita; Fischbacher, Colin; Dibben, Christopher; Shields, Michael; Phillips, Ceri; Strachan, David; Davies, Gwyneth; McKinstry, Brian; Sheikh, Aziz

    2014-01-01

    Introduction Asthma is now one of the most common long-term conditions in the UK. It is therefore important to develop a comprehensive appreciation of the healthcare and societal costs in order to inform decisions on care provision and planning. We plan to build on our earlier estimates of national prevalence and costs from asthma by filling the data gaps previously identified in relation to healthcare and broadening the field of enquiry to include societal costs. This work will provide the first UK-wide estimates of the costs of asthma. In the context of asthma for the UK and its member countries (ie, England, Northern Ireland, Scotland and Wales), we seek to: (1) produce a detailed overview of estimates of incidence, prevalence and healthcare utilisation; (2) estimate health and societal costs; (3) identify any remaining information gaps and explore the feasibility of filling these and (4) provide insights into future research that has the potential to inform changes in policy leading to the provision of more cost-effective care. Methods and analysis Secondary analyses of data from national health surveys, primary care, prescribing, emergency care, hospital, mortality and administrative data sources will be undertaken to estimate prevalence, healthcare utilisation and outcomes from asthma. Data linkages and economic modelling will be undertaken in an attempt to populate data gaps and estimate costs. Separate prevalence and cost estimates will be calculated for each of the UK-member countries and these will then be aggregated to generate UK-wide estimates. Ethics and dissemination Approvals have been obtained from the NHS Scotland Information Services Division's Privacy Advisory Committee, the Secure Anonymised Information Linkage Collaboration Review System, the NHS South-East Scotland Research Ethics Service and The University of Edinburgh's Centre for Population Health Sciences Research Ethics Committee. We will produce a report for Asthma-UK, submit papers to peer-reviewed journals and construct an interactive map. PMID:25371419

  14. New Mission Control Center Briefing

    NASA Technical Reports Server (NTRS)

    1995-01-01

    Live footage shows panelists, Chief Center Systems Division John Muratore, and Acting Chief, Control Center Systems Division, Linda Uljon, giving an overview of the new Mission Control Center. Muratore and Uljon talk about the changes and modernization of the new Center. The panelists mention all the new capabilities of the new Center. They emphasize the Distributed real time command and control environment, the reduction in operation costs, and even the change from coaxial cables to fiber optic cables. Uljon also tells us that the new Control Center will experience its first mission after the launch of STS-70 and its first complete mission (both launching and landing) during STS-71.

  15. Coherent UDWDM PON with joint subcarrier reception at OLT.

    PubMed

    Kottke, Christoph; Fischer, Johannes Karl; Elschner, Robert; Frey, Felix; Hilt, Jonas; Schubert, Colja; Schmidt, Daniel; Wu, Zifeng; Lankl, Berthold

    2014-07-14

    In this contribution, we report on the experimental investigation of an ultra-dense wavelength-division multiplexing (UDWDM) upstream link with up to 700 × 2.488 Gb/s polarization-division multiplexing differential quadrature phase-shift keying parallel upstream user channels transmitted over 80 km of standard single-mode fiber. We discuss challenges of the digital signal processing in the optical line terminal arising from the joint reception of several upstream user channels. We present solutions for resource and cost-efficient realization of the required channel separation, matched filtering, down-conversion and decimation as well as realization of the clock recovery and polarization demultiplexing for each individual channel.

  16. Leadership Primer for Current and Aspiring Pulmonary, Critical Care, and Sleep Medicine Academic Division Chiefs.

    PubMed

    Nguyen, H Bryant; Thomson, Carey C; Kaminski, Naftali; Schnapp, Lynn M; Madison, J Mark; Glenny, Robb W; Dixon, Anne E

    2018-02-27

    An academic medical career traditionally revolves around patient care, teaching, and scholarly projects. Thus, when an opportunity for a leadership role arises, such as Division Chief, the new leader is often unprepared with little or no formal leadership training. In this article, academic leaders of the Association of Pulmonary, Critical Care and Sleep Division Directors reviewed several leadership concepts adapted from the business sector and applied years of their experience to aid new division chiefs with their first day on the job. The first 90 days are highlighted to include accomplishing the early wins, performing a division Strengths, Weaknesses, Opportunities, and Threats (SWOT) analysis, establishing division rapport, redefining the division infrastructure, avoiding conflicts, and managing their relationship with the department chair. The five levels of leadership applicable to academic medicine are discussed: position, permission, production, people, and pinnacle. Finally, emotional intelligence and behavior styles crucial to leadership success are reviewed.

  17. An Analysis of the Perceptions of Division Senior Combat Arms Leaders of the Tactical Competence of Division Signal Officers and Assistant Division Signal Officers.

    DTIC Science & Technology

    1987-06-05

    field the equipment ( Valletta , 1980). The need for signal officers to be trained to employ new communications systems in support of the tactical...Gordon, GAO 30905). Valletta , A. M. (1980). Tactical automnation-communications: Supporting corps rear to front line. Army Magazine, 1(4), 25-28

  18. Functional redundancy of division specific penicillin-binding proteins in Bacillus subtilis.

    PubMed

    Sassine, Jad; Xu, Meizhu; Sidiq, Karzan R; Emmins, Robyn; Errington, Jeff; Daniel, Richard A

    2017-10-01

    Bacterial cell division involves the dynamic assembly of a diverse set of proteins that coordinate the invagination of the cell membrane and synthesis of cell wall material to create the new cell poles of the separated daughter cells. Penicillin-binding protein PBP 2B is a key cell division protein in Bacillus subtilis proposed to have a specific catalytic role in septal wall synthesis. Unexpectedly, we find that a catalytically inactive mutant of PBP 2B supports cell division, but in this background the normally dispensable PBP 3 becomes essential. Phenotypic analysis of pbpC mutants (encoding PBP 3) shows that PBP 2B has a crucial structural role in assembly of the division complex, independent of catalysis, and that its biochemical activity in septum formation can be provided by PBP 3. Bioinformatic analysis revealed a close sequence relationship between PBP 3 and Staphylococcus aureus PBP 2A, which is responsible for methicillin resistance. These findings suggest that mechanisms for rescuing cell division when the biochemical activity of PBP 2B is perturbed evolved prior to the clinical use of β-lactams. © 2017 The Authors. Molecular Microbiology published by John Wiley & Sons Ltd.

  19. An analysis of the magnitude and frequency of floods on Oahu, Hawaii

    USGS Publications Warehouse

    Nakahara, R.H.

    1980-01-01

    An analysis of available peak-flow data for the island of Oahu, Hawaii, was made by using multiple regression techniques which related flood-frequency data to basin and climatic characteristics for 74 gaging stations on Oahu. In the analysis, several different groupings of stations were investigated, including divisions by geographic location and size of drainage area. The grouping consisting of two leeward divisions and one windward division produced the best results. Drainage basins ranged in area from 0.03 to 45.7 square miles. Equations relating flood magnitudes of selected frequencies to basin characteristics were developed for the three divisions of Oahu. These equations can be used to estimate the magnitude and frequency of floods for any site, gaged or ungaged, for any desired recurrence interval from 2 to 100 years. Data on basin characteristics, flood magnitudes for various recurrence intervals from individual station-frequency curves, and computed flood magnitudes by use of the regression equation are tabulated to provide the needed data. (USGS)

  20. Optimization of location routing inventory problem with transshipment

    NASA Astrophysics Data System (ADS)

    Ghani, Nor Edayu Abd; Shariff, S. Sarifah Radiah; Zahari, Siti Meriam

    2015-05-01

    Location Routing Inventory Problem (LRIP) is a collaboration of the three components in the supply chain. It is confined by location-allocation, vehicle routing and inventory management. The aim of the study is to minimize the total system cost in the supply chain. Transshipment is introduced in order to allow the products to be shipped to a customer who experiences a shortage, either directly from the supplier or from another customer. In the study, LRIP is introduced with the transshipment (LRIPT) and customers act as the transshipment points. We select the transshipment point by using the p-center and we present the results in two divisions of cases. Based on the analysis, the results indicated that LRIPT performed well compared to LRIP.

  1. Estimating division and death rates from CFSE data

    NASA Astrophysics Data System (ADS)

    de Boer, Rob J.; Perelson, Alan S.

    2005-12-01

    The division tracking dye, carboxyfluorescin diacetate succinimidyl ester (CFSE) is currently the most informative labeling technique for characterizing the division history of cells in the immune system. Gett and Hodgkin (Nat. Immunol. 1 (2000) 239-244) have proposed to normalize CFSE data by the 2-fold expansion that is associated with each division, and have argued that the mean of the normalized data increases linearly with time, t, with a slope reflecting the division rate p. We develop a number of mathematical models for the clonal expansion of quiescent cells after stimulation and show, within the context of these models, under which conditions this approach is valid. We compare three means of the distribution of cells over the CFSE profile at time t: the mean, [mu](t), the mean of the normalized distribution, [mu]2(t), and the mean of the normalized distribution excluding nondivided cells, .In the simplest models, which deal with homogeneous populations of cells with constant division and death rates, the normalized frequency distribution of the cells over the respective division numbers is a Poisson distribution with mean [mu]2(t)=pt, where p is the division rate. The fact that in the data these distributions seem Gaussian is therefore insufficient to establish that the times at which cells are recruited into the first division have a Gaussian variation because the Poisson distribution approaches the Gaussian distribution for large pt. Excluding nondivided cells complicates the data analysis because , and only approaches a slope p after an initial transient.In models where the first division of the quiescent cells takes longer than later divisions, all three means have an initial transient before they approach an asymptotic regime, which is the expected [mu](t)=2pt and . Such a transient markedly complicates the data analysis. After the same initial transients, the normalized cell numbers tend to decrease at a rate e-dt, where d is the death rate.Nonlinear parameter fitting of CFSE data obtained from Gett and Hodgkin to ordinary differential equation (ODE) models with first-order terms for cell proliferation and death gave poor fits to the data. The Smith-Martin model with an explicit time delay for the deterministic phase of the cell cycle performed much better. Nevertheless, the insights gained from analysis of the ODEs proved useful as we showed by generating virtual CFSE data with a simulation model, where cell cycle times were drawn from various distributions, and then computing the various mean division numbers.

  2. Innovation and Antitrust: Some Thoughts on Government Patent Policy.

    ERIC Educational Resources Information Center

    Ewng, Ky P., Jr.

    1978-01-01

    Government patent policy and the effect of antitrust legislation on innovation are discussed along with the efforts of the Antitrust Division of the Justice Department to formulate new government patent policy recommendations. Participation, disclosure, commercialization, and administrative cost are discussed as issues that concern the patent…

  3. 75 FR 34336 - Reimbursement Transportation Cost Payment Program for Geographically Disadvantaged Farmers and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-17

    ..., 2010. FOR FURTHER INFORMATION CONTACT: Solomon Whitfield, Director, Price Support Division, Farm...., Washington, DC 20250-0512; telephone (202) 720-7901; fax (202) 690- 3307; e-mail, Solomon[email protected], group of individuals, partnership, corporation, estate, trust, association, cooperative, or other...

  4. 23 CFR 635.104 - Method of construction.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... STD demonstrates to the satisfaction of the Division Administrator that some other method is more cost effective or that an emergency exists. The STD shall assure opportunity for free, open, and competitive... this chapter. Before such finding is made, the STD shall determine that the organization to undertake...

  5. 23 CFR 635.104 - Method of construction.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... STD demonstrates to the satisfaction of the Division Administrator that some other method is more cost effective or that an emergency exists. The STD shall assure opportunity for free, open, and competitive... this chapter. Before such finding is made, the STD shall determine that the organization to undertake...

  6. 23 CFR 635.104 - Method of construction.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... STD demonstrates to the satisfaction of the Division Administrator that some other method is more cost effective or that an emergency exists. The STD shall assure opportunity for free, open, and competitive... this chapter. Before such finding is made, the STD shall determine that the organization to undertake...

  7. 23 CFR 635.104 - Method of construction.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... STD demonstrates to the satisfaction of the Division Administrator that some other method is more cost effective or that an emergency exists. The STD shall assure opportunity for free, open, and competitive... this chapter. Before such finding is made, the STD shall determine that the organization to undertake...

  8. Experiences in Training End-User Searchers.

    ERIC Educational Resources Information Center

    Haines, Judith S.

    1982-01-01

    Describes study of chemists in the Chemistry Division, Organic Research Laboratory, Eastman Kodak Company, as end-user searchers on the DIALOG system searching primarily the "Chemical Abstracts" database. Training, level of use, online browsing, types of searches, satisfaction, costs, and value of end-user searching are highlighted.…

  9. RADON REMOVAL BY POINT-OF-ENTRY GRANULAR ACTIVATED CARBON SYSTEMS: DESIGN PERFORMANCE AND COST

    EPA Science Inventory

    The report summarizes previous research conducted by Lowry Engineering, Inc. (LEI), the Maine Department of Human Services, Division of Health Engineering, and the University of Maine, Department of Civil Engineering, on the removal of Rn from drinking water supplies using granul...

  10. 78 FR 30798 - Notice of Intent To Request Public Comments

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-23

    ... of 2016. Home Insulation. 682 Disposal of Consumer Report 2016. Information and Records. 233 Guides... or guide's costs and benefits to consumers and businesses. Based on this feedback, the Commission may..., Federal Trade Commission, Bureau of Consumer Protection, Division of Marketing Practices, 600 Pennsylvania...

  11. Knowledge-based assistance in costing the space station DMS

    NASA Technical Reports Server (NTRS)

    Henson, Troy; Rone, Kyle

    1988-01-01

    The Software Cost Engineering (SCE) methodology developed over the last two decades at IBM Systems Integration Division (SID) in Houston is utilized to cost the NASA Space Station Data Management System (DMS). An ongoing project to capture this methodology, which is built on a foundation of experiences and lessons learned, has resulted in the development of an internal-use-only, PC-based prototype that integrates algorithmic tools with knowledge-based decision support assistants. This prototype Software Cost Engineering Automation Tool (SCEAT) is being employed to assist in the DMS costing exercises. At the same time, DMS costing serves as a forcing function and provides a platform for the continuing, iterative development, calibration, and validation and verification of SCEAT. The data that forms the cost engineering database is derived from more than 15 years of development of NASA Space Shuttle software, ranging from low criticality, low complexity support tools to highly complex and highly critical onboard software.

  12. An American OMG? The Air Assault Division Employed As An Operational Maneuver Group,

    DTIC Science & Technology

    1992-05-15

    been planned, rehearsed 32 and executed. Failure is the " cost " for over extending lines of operation and communications. Two cases, Marshal Pilsudski’s...attrition on their flanks and rear, and lines of communication are non- existent, life will be short for the OMG and the cost to the Soviets high. 160...undated), pp. 24-25. Hereafter cited as Kipp, Historical Reflections. 11. The summary of doctrine from 1977-1981 was paraphrased from Kipp, Historcal

  13. Automated Sneak Circuit Analysis Technique

    DTIC Science & Technology

    1990-06-01

    the OrCAD/SDT module Port facility. 2. The terminals of all in- circuit voltage sources (e , batteries) must be labeled using the OrCAD/SDT module port...ELECTE 1 MAY 2 01994 _- AUTOMATED SNEAK CIRCUIT ANALYSIS TECHNIQUEIt~ w I wtA who RADC 94-14062 Systems Reliability & Engineering Division Rome...Air Develpment Center Best Avai~lable copy AUTOMATED SNEAK CIRCUIT ANALYSIS TECHNIQUE RADC June 1990 Systems Reliability & Engineering Division Rome Air

  14. Low-cost interferometric TDM technology for dynamic sensing applications

    NASA Astrophysics Data System (ADS)

    Bush, Jeff; Cekorich, Allen

    2004-12-01

    A low-cost design approach for Time Division Multiplexed (TDM) fiber-optic interferometric interrogation of multi-channel sensor arrays is presented. This paper describes the evolutionary design process of the subject design. First, the requisite elements of interferometric interrogation are defined for a single channel sensor. The concept is then extended to multi-channel sensor interrogation implementing a TDM multiplex scheme where "traditional" design elements are utilized. The cost of the traditional TDM interrogator is investigated and concluded to be too high for entry into many markets. A new design approach is presented which significantly reduces the cost for TDM interrogation. This new approach, in accordance with the cost objectives, shows promise to bring this technology to within the threshold of commercial acceptance for a wide range of distributed fiber sensing applications.

  15. Publications - GMC 18 | Alaska Division of Geological & Geophysical Surveys

    Science.gov Websites

    Authors: Unknown Publication Date: Unknown Publisher: Alaska Division of Geological & Geophysical information. Bibliographic Reference Unknown, [n.d.], Geochemical analysis (total organic carbon, rock-eval

  16. Publications - GMC 46 | Alaska Division of Geological & Geophysical Surveys

    Science.gov Websites

    wells Authors: Unknown Publication Date: 1984 Publisher: Alaska Division of Geological & Geophysical information. Bibliographic Reference Unknown, 1984, Shale bulk density analysis of cuttings from 10 North

  17. The 91st Infantry in World War I -- Analysis of an AEF Division’s Efforts to Achieve Battlefield Success

    DTIC Science & Technology

    2013-06-13

    collaboration with John J. Pershing, “Who Won the War” ( Typescript copy held in the Duane N. Diedrich Collection, Clements Library, University of...trusted to luck.”74 73The Training and Employment of Divisions, 1918, 71. 74Diary of Lieutenant Charles H. Paul, 364th Infantry, 91st Division ( typescript ...accessed 19 May 2013). Diary of Gaylen Snow, 362nd Infantry, 91st Division. Typescript held at Brigham Young University, UT. 79 Diary of Lieutenant

  18. Population genetics of Vibrio vulnificus: identification of two divisions and a distinct eel-pathogenic clone.

    PubMed

    Gutacker, Michaela; Conza, Nadine; Benagli, Cinzia; Pedroli, Ambra; Bernasconi, Marco Valerio; Permin, Lise; Aznar, Rosa; Piffaretti, Jean-Claude

    2003-06-01

    Genetic relationships among 62 Vibrio vulnificus strains of different geographical and host origins were analyzed by multilocus enzyme electrophoresis (MLEE), random amplification of polymorphic DNA (RAPD), and sequence analyses of the recA and glnA genes. Out of 15 genetic loci analyzed by MLEE, 11 were polymorphic. Cluster analysis identified 43 distinct electrophoretic types (ETs) separating the V. vulnificus population into two divisions (divisions I and II). One ET (ET 35) included all indole-negative isolates from diseased eels worldwide (biotype 2). A second ET (ET 2) marked all of the strains from Israel isolated from patients who handled St. Peter's fish (biotype 3). RAPD analysis of the 62 V. vulnificus isolates identified 26 different profiles separated into two divisions as well. In general, this subdivision was comparable (but not identical) to that observed by MLEE. Phylogenetic analysis of 543 bp of the recA gene and of 402 bp of the glnA gene also separated the V. vulnificus population into two major divisions in a manner similar to that by MLEE and RAPD. Sequence data again indicated the overall subdivision of the V. vulnificus population into different biotypes. In particular, indole-negative eel-pathogenic isolates (biotype 2) on one hand and the Israeli isolates (biotype 3) on the other tended to cluster together in both gene trees. None of the methods showed an association between distinct clones and human clinical manifestations. Furthermore, except for the Israeli strains, only minor clusters comprising geographically related isolates were observed. In conclusion, all three approaches (MLEE, RAPD, and DNA sequencing) generated comparable but not always equivalent results. The significance of the two divisions (divisions I and II) still remains to be clarified, and a reevaluation of the definition of the biotypes is also needed.

  19. Publications - GMC 21 | Alaska Division of Geological & Geophysical Surveys

    Science.gov Websites

    #1 well Authors: Unknown Publication Date: Unknown Publisher: Alaska Division of Geological & for more information. Bibliographic Reference Unknown, [n.d.], Visual kerogen analysis - transmitted

  20. Heating, Ventilation, and Air Conditioning Design Strategy for a Hot-Humid Production Builder

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kerrigan, P.

    2014-03-01

    BSC worked directly with the David Weekley Homes - Houston division to redesign three floor plans in order to locate the HVAC system in conditioned space. The purpose of this project is to develop a cost effective design for moving the HVAC system into conditioned space. In addition, BSC conducted energy analysis to calculate the most economical strategy for increasing the energy performance of future production houses. This is in preparation for the upcoming code changes in 2015. The builder wishes to develop an upgrade package that will allow for a seamless transition to the new code mandate. The followingmore » research questions were addressed by this research project: 1. What is the most cost effective, best performing and most easily replicable method of locating ducts inside conditioned space for a hot-humid production home builder that constructs one and two story single family detached residences? 2. What is a cost effective and practical method of achieving 50% source energy savings vs. the 2006 International Energy Conservation Code for a hot-humid production builder? 3. How accurate are the pre-construction whole house cost estimates compared to confirmed post construction actual cost? BSC and the builder developed a duct design strategy that employs a system of dropped ceilings and attic coffers for moving the ductwork from the vented attic to conditioned space. The furnace has been moved to either a mechanical closet in the conditioned living space or a coffered space in the attic.« less

  1. HVAC Design Strategy for a Hot-Humid Production Builder, Houston, Texas (Fact Sheet)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    None, None

    BSC worked directly with the David Weekley Homes - Houston division to redesign three floor plans in order to locate the HVAC system in conditioned space. The purpose of this project is to develop a cost effective design for moving the HVAC system into conditioned space. In addition, BSC conducted energy analysis to calculate the most economical strategy for increasing the energy performance of future production houses. This is in preparation for the upcoming code changes in 2015. The builder wishes to develop an upgrade package that will allow for a seamless transition to the new code mandate. The followingmore » research questions were addressed by this research project: 1. What is the most cost effective, best performing and most easily replicable method of locating ducts inside conditioned space for a hot-humid production home builder that constructs one and two story single family detached residences? 2. What is a cost effective and practical method of achieving 50% source energy savings vs. the 2006 International Energy Conservation Code for a hot-humid production builder? 3. How accurate are the pre-construction whole house cost estimates compared to confirmed post construction actual cost? BSC and the builder developed a duct design strategy that employs a system of dropped ceilings and attic coffers for moving the ductwork from the vented attic to conditioned space. The furnace has been moved to either a mechanical closet in the conditioned living space or a coffered space in the attic.« less

  2. Patterns and Trends in Services to Persons on the Caseload of the Division of Developmental Disabilities: A 5-Year Analysis (July 1989-August 1994).

    ERIC Educational Resources Information Center

    Weber, Lisa A.; And Others

    This report presents patterns and trends in services provided to persons with developmental disabilities through the Washington State Division of Developmental Disabilities (DDD) and related agencies from 1989 through 1994. Following an executive summary, individual chapters provide extensive detail on: (1) the Division and this project; (2) types…

  3. Division and Brigade Stationing System: Installation Data Book.

    DTIC Science & Technology

    1988-04-01

    8217Division and Brigade Stationing Study: An Analysis of Environmental and Socioeconomic Effects (ESC, September 1987); Division and Brigade Stationing Study...composed of 0 partly decomposed moss, leaves , and twigs, matted together with many fine rootlets. In permafrost areas, destruction of this mat...maritime effect is seldom interrupted by drier and cooler continental air. Although rainfall averages about 48 inches a year, Y annual variation is large

  4. Cost-effective and monitoring-active technique for TDM-passive optical networks

    NASA Astrophysics Data System (ADS)

    Chi, Chang-Chia; Lin, Hong-Mao; Tarn, Chen-Wen; Lin, Huang-Liang

    2014-08-01

    A reliable, detection-active and cost-effective method which employs the hello and heartbeat signals for branched node distinguishing to monitor fiber fault in any branch of distribution fibers of a time division multiplexing passive optical network (TDM-PON) is proposed. With this method, the material cost of building an optical network monitor system for a TDM-PON with 168 ONUs and the time of identifying a multiple branch faults is significantly reduced in a TDM-PON system of any scale. A fault location in a 1 × 32 TDM-PON system using this method to identify the fault branch is demonstrated.

  5. Multiple access techniques and spectrum utilization of the GLOBALSTAR mobile satellite system

    NASA Astrophysics Data System (ADS)

    Louie, Ming; Cohen, Michel; Rouffet, Denis; Gilhousen, Klein S.

    The GLOBALSTAR System is a Low Earth Orbit (LEO) satellite-based mobile communications system that is interoperable with the current and future Public Land Mobile Network (PLMN). The GLOBALSTAR System concept is based upon technological advancement in two key areas: (1) the advancement in LEO satellite technology; (2) the advancement in cellular telephone technology, including the commercial applications of Code Division Multiple Access (CDMA) technologies, and of the most recent progress in Time Division Multiple Access technologies. The GLOBALSTAR System uses elements of CDMA, Frequency Division Multiple Access (FDMA), and Time Division Multiple Access (TDMA) technology, combining with satellite Multiple Beam Antenna (MBA) technology, to arrive at one of the most efficient modulation and multiple access system ever proposed for a satellite communications system. The technology used in GLOBALSTAR exploits the following techniques in obtaining high spectral efficiency and affordable cost per channel, with minimum coordination among different systems: power control, in open and closed loops, voice activation, spot beam satellite antenna for frequency reuse, weighted satellite antenna gain, multiple satellite coverage, and handoff between satellites. The GLOBALSTAR system design will use the following frequency bands: 1610-1626.5 MHz for up-link and 2483.5-2500 MHz for down-link.

  6. 76 FR 65112 - James Zadroga 9/11 Health and Compensation Act of 2010

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-20

    ...: Kenneth L. Zwick, Director, Office of Management Programs, Civil Division, U.S. Department of Justice... of 1996'' is revised to read as follows: ``The Office of Management and Budget has determined that... increase in costs or prices, or significant adverse effects on competition, employment, investment...

  7. Alphabet Keyboard. MicroSIFT Courseware Evaluation.

    ERIC Educational Resources Information Center

    Northwest Regional Educational Lab., Portland, OR.

    THE FOLLOWING IS THE FULL TEXT OF THIS DOCUMENT (Except for the Evaluation Summary Table): PRODUCER: Random House, Inc., School Division, 1970 Brandywine Rd., Atlanta, Georgia 30341. EVALUATION COMPLETED: June 1982 by staff of the Portland Public Schools, Oregon. COST: Cassette: $24 Disk: $34.50. ABILITY LEVEL: K-1. SUBJECT: Reading: location of…

  8. The Complete Guide to Job Sharing.

    ERIC Educational Resources Information Center

    Hohn, Marcia D.

    This booklet provides information on job sharing that resulted from the research and experience of the Merrimack Valley Job Sharing Project. An overview of the topic considers the need for job sharing, employer benefits, types of jobs shared, job division, benefits, employer costs and savings, financial considerations for job sharers, perspectives…

  9. History of the Pacific Ocean Division Corps of Engineers 1957-1967

    DTIC Science & Technology

    1972-01-01

    mound barrier; designed by HED civil engineer Robert Q. Palmer, these concrete three-bar struc- tures provided a sturdy substitute for scarce rock...that metal buildings would require high main- tenance costs, while the termite problem eliminates construction in wood. Not only for these reasons

  10. 78 FR 78013 - Focused Mitigation Strategies To Protect Food Against Intentional Adulteration

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-24

    ... and procedures; I--Inspect your work area and surrounding areas; R--Recognize anything out of the...: Mail/Hand delivery/Courier (for paper or CD-ROM submissions): Division of Dockets Management (HFA-305... Proposed Rule Costs and Benefits I. Introduction II. Background A. Incidents of Intentional Adulteration of...

  11. 45 CFR 95.507 - Plan requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... costs to each of the programs operated by the State agency; (2) Conform to the accounting principles and standards prescribed in Office of Management and Budget Circular A-87, and other pertinent Department... with the Operating Divisions, to make an informed judgment on the correctness and fairness of the State...

  12. College Stores 1975--A Challenge to the Publishers

    ERIC Educational Resources Information Center

    Davis, Howard W.

    1976-01-01

    A presentation by the general manager of the Harvard Cooperative Society to the College Division of the Association of American Publishers in which he illustrates with survey data the contention that suggested publishers prices for textbooks are arbitrarily set too low by publishers to cover minimal costs of marketing textbooks. (JT)

  13. 75 FR 39261 - Agency Forms Undergoing Paperwork Reduction Act Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-08

    ... Project Improving the Quality and Delivery of CDC's Heart Disease and Stroke Prevention Programs--New--Division for Heart Disease and Stroke Prevention (DHDSP), National Center for Chronic Disease Prevention... Description Heart disease and stroke are among the most widespread and costly causes of death and disability...

  14. 75 FR 13304 - Notice of Lodging of Consent Decree Under the Oil Pollution Act (OPA)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-19

    ...., will pay assessment costs and natural resource damages totaling $588,000. The Natural Resources Trustees developed a proposed Restoration Plan and Environmental Assessment in connection with the Spill... Attorney General, Environment and Natural Resources Division, and either e-mailed to pubcomment-ees.enrd...

  15. 75 FR 6220 - Notice of Lodging of Consent Decree Under the Comprehensive Environmental Response, Compensation...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-08

    ... settles claims for natural resource damages under the Comprehensive Environmental Response, Compensation... natural resource trustees for any unreimbursed assessment costs incurred by the State and Federal natural... Assistant Attorney General, Environment and Natural Resources Division, and either e-mailed to pubcomment...

  16. Planning, Implementing, and Documenting an Innovative Statewide Occupational Initiative.

    ERIC Educational Resources Information Center

    Floyd, Jerald D.

    During an 18-month demonstration period, the Illinois Occupational Program Initiative (IOPI), funded through the state's Division of Alcoholism, demonstrated the feasibility of funding individual contractors to create and market employee assistance programs (EAPs) to representatives of industry and labor. Cost estimates for the EAPs were to cover…

  17. 78 FR 11683 - Division of Federal Employees' Compensation; Proposed Extension of Existing Collection; Comment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-19

    ... 8104(a) of the FECA provides vocational rehabilitation services to eligible injured workers to facilitate their return to work. The costs of providing these vocational rehabilitation services are paid..., 2013. II. Review Focus: The Department of Labor is particularly interested in comments which...

  18. Issuance of driver licenses and identification cards to prisoners : appendix C, travel cost assumptions and details.

    DOT National Transportation Integrated Search

    2010-06-01

    In 2009, the Oregon Legislature passed House Bill 2489, requiring the Oregon Driver and Motor Vehicle (DMV) Services Division and the Department of Corrections (DOC) to enter into agreements and adopt rules to assist offenders in obtaining a driver l...

  19. Challenges in Chemistry Graduate Education: A Workshop Summary

    ERIC Educational Resources Information Center

    National Academies Press, 2012

    2012-01-01

    Chemistry graduate education is under considerable pressure. Pharmaceutical companies, long a major employer of synthetic organic chemists, are drastically paring back their research divisions to reduce costs. Chemical companies are opening new research and development facilities in Asia rather than in the United States to take advantage of…

  20. RESEARCH AREA -- POLLUTION PREVENTION (P2) (EMISSIONS CHARACTERIZATION AND PREVENTION BRANCH, AIR POLLUTION PREVENTION AND CONTROL DIVISION, NRMRL)

    EPA Science Inventory

    The objective of this program is to develop and demonstrate technologies, processes, and products that will prevent the formation of hazardous emission or criteria pollutants. The pollution prevention alternatives are often no more costly (and sometimes even less) than tradition...

  1. Documentation Across the Services

    DTIC Science & Technology

    2017-05-19

    you they cannot fund your publication, the 59th Clinical Research Division may pay for your basic journal publishing charges (to include costs for...tables and black and white photos). We cannot pay for reprints. If you are a 59 MDW staff member, we can forward your request for funds to the designated

  2. Landmark-Based Navigation of an Unmanned Ground Vehicle (UGV)

    DTIC Science & Technology

    2009-03-01

    against large measurement errors. 20090710280 RELEASE LIMITATION Approved for public release 4p fv^-Jo-osiit? Published by Weapons Systems Division...achieved as numerous low cost gyroscopes in the market meet this requirement. 24 DSTO-TR-2260 3.5.4 Sensitivity to Vehicle Speed In this subsection

  3. High efficiency diffraction grating technologies LPDL 900 and LPDL 1100 in telecommunications applications

    NASA Astrophysics Data System (ADS)

    Milner, Darrin; Didona, Kevin; Bannon, David

    2005-04-01

    With the introduction of wavelength division multiplexing and dense wavelength division multiplexing, equipment manufactures have sought to reduce design tradeoffs and costs while maintaining or increasing their product performance. With the need to reduce if not eliminate optical losses and create the all light path from source to destination, equipment manufactures are addressing the concerns of component manufactures to provide increased performance to support configurable designs for 100, 50, and eventually 12.5GHz. One of the most reliable, robust, and high performance devices is the low polarization dependent loss (LPDL) diffraction grating used to disperse wavelengths for channel blocking, add/drop functionality and real time light path reconfigurations. The networks today have a variety of factors which contribute to the optical loss budget and impact system design cost, facility requirements, maintenance or replacement costs. These factors include first and second order polarization mode dispersion (PMD), polarization dependent loss (PDL), wavelength dependent losses, and chromatic dispersion (CD). Network designers and equipment manufactures have to consider each component capability and its impact to the systems bit error rate (BER). In order to gain an understanding of the advantages of components with low polarization dependency, we will summarize the effects that interplay with these types of components.

  4. A simplified Integer Cosine Transform and its application in image compression

    NASA Technical Reports Server (NTRS)

    Costa, M.; Tong, K.

    1994-01-01

    A simplified version of the integer cosine transform (ICT) is described. For practical reasons, the transform is considered jointly with the quantization of its coefficients. It differs from conventional ICT algorithms in that the combined factors for normalization and quantization are approximated by powers of two. In conventional algorithms, the normalization/quantization stage typically requires as many integer divisions as the number of transform coefficients. By restricting the factors to powers of two, these divisions can be performed by variable shifts in the binary representation of the coefficients, with speed and cost advantages to the hardware implementation of the algorithm. The error introduced by the factor approximations is compensated for in the inverse ICT operation, executed with floating point precision. The simplified ICT algorithm has potential applications in image-compression systems with disparate cost and speed requirements in the encoder and decoder ends. For example, in deep space image telemetry, the image processors on board the spacecraft could take advantage of the simplified, faster encoding operation, which would be adjusted on the ground, with high-precision arithmetic. A dual application is found in compressed video broadcasting. Here, a fast, high-performance processor at the transmitter would precompensate for the factor approximations in the inverse ICT operation, to be performed in real time, at a large number of low-cost receivers.

  5. [Efficiency assessment of investment in workers' health--economic issues].

    PubMed

    Rydlewska-Liszkowska, Izabela; Dawydzik, Lech T

    2002-01-01

    The economic analysis of efficiency of investment in health care and health at large by means of cost-benefit or cost-effectiveness techniques is the subject of implementation work in a number of countries. Poland's integration with the countries of the European Union justifies the need to understand and to use economic analyses. Unfortunately, these activities encounter many methodological and executive barriers. The investments in workers' health are not only investments in health care and the improvement of working conditions, but also in compensations, including financial ones, resulting from adverse effects of factors influencing the health of working population. The financial reporting system that exists in Poland does not ensure the possibility of full presentation of the aggregated data on the financing of activities for workers' health and diminishing of the adverse effects of factors present in the work environment. The information on the outcome of the investments in workers' health come from different sources, which means that it applies to different groups subjected to the analysis. The problem lies not only in the assessment of profitability of health investments but also in the social problem of the division of the resultant costs and benefits among various branches of the national economy. Therefore, the analyses involving mutual relations between individual sectors that invest in workers' health and those that bear consequences is essential in the terms of economic analyses. The authors present the determinants of economic evaluation in regard to health of working population in Poland.

  6. Advanced Spatial-Division Multiplexed Measurement Systems Propositions—From Telecommunication to Sensing Applications: A Review

    PubMed Central

    Weng, Yi; Ip, Ezra; Pan, Zhongqi; Wang, Ting

    2016-01-01

    The concepts of spatial-division multiplexing (SDM) technology were first proposed in the telecommunications industry as an indispensable solution to reduce the cost-per-bit of optical fiber transmission. Recently, such spatial channels and modes have been applied in optical sensing applications where the returned echo is analyzed for the collection of essential environmental information. The key advantages of implementing SDM techniques in optical measurement systems include the multi-parameter discriminative capability and accuracy improvement. In this paper, to help readers without a telecommunication background better understand how the SDM-based sensing systems can be incorporated, the crucial components of SDM techniques, such as laser beam shaping, mode generation and conversion, multimode or multicore elements using special fibers and multiplexers are introduced, along with the recent developments in SDM amplifiers, opto-electronic sources and detection units of sensing systems. The examples of SDM-based sensing systems not only include Brillouin optical time-domain reflectometry or Brillouin optical time-domain analysis (BOTDR/BOTDA) using few-mode fibers (FMF) and the multicore fiber (MCF) based integrated fiber Bragg grating (FBG) sensors, but also involve the widely used components with their whole information used in the full multimode constructions, such as the whispering gallery modes for fiber profiling and chemical species measurements, the screw/twisted modes for examining water quality, as well as the optical beam shaping to improve cantilever deflection measurements. Besides, the various applications of SDM sensors, the cost efficiency issue, as well as how these complex mode multiplexing techniques might improve the standard fiber-optic sensor approaches using single-mode fibers (SMF) and photonic crystal fibers (PCF) have also been summarized. Finally, we conclude with a prospective outlook for the opportunities and challenges of SDM technologies in optical sensing industry. PMID:27589754

  7. Advanced Spatial-Division Multiplexed Measurement Systems Propositions-From Telecommunication to Sensing Applications: A Review.

    PubMed

    Weng, Yi; Ip, Ezra; Pan, Zhongqi; Wang, Ting

    2016-08-30

    The concepts of spatial-division multiplexing (SDM) technology were first proposed in the telecommunications industry as an indispensable solution to reduce the cost-per-bit of optical fiber transmission. Recently, such spatial channels and modes have been applied in optical sensing applications where the returned echo is analyzed for the collection of essential environmental information. The key advantages of implementing SDM techniques in optical measurement systems include the multi-parameter discriminative capability and accuracy improvement. In this paper, to help readers without a telecommunication background better understand how the SDM-based sensing systems can be incorporated, the crucial components of SDM techniques, such as laser beam shaping, mode generation and conversion, multimode or multicore elements using special fibers and multiplexers are introduced, along with the recent developments in SDM amplifiers, opto-electronic sources and detection units of sensing systems. The examples of SDM-based sensing systems not only include Brillouin optical time-domain reflectometry or Brillouin optical time-domain analysis (BOTDR/BOTDA) using few-mode fibers (FMF) and the multicore fiber (MCF) based integrated fiber Bragg grating (FBG) sensors, but also involve the widely used components with their whole information used in the full multimode constructions, such as the whispering gallery modes for fiber profiling and chemical species measurements, the screw/twisted modes for examining water quality, as well as the optical beam shaping to improve cantilever deflection measurements. Besides, the various applications of SDM sensors, the cost efficiency issue, as well as how these complex mode multiplexing techniques might improve the standard fiber-optic sensor approaches using single-mode fibers (SMF) and photonic crystal fibers (PCF) have also been summarized. Finally, we conclude with a prospective outlook for the opportunities and challenges of SDM technologies in optical sensing industry.

  8. Metabolomic analysis of the green microalga Chlamydomonas reinhardtii cultivated under day/night conditions.

    PubMed

    Willamme, Rémi; Alsafra, Zouheir; Arumugam, Rameshkumar; Eppe, Gauthier; Remacle, Françoise; Levine, R D; Remacle, Claire

    2015-12-10

    Biomass composition of Chlamydomonas reinhardtii was studied during two consecutive cycles of 12h light/12h dark. As in our experimental conditions the two synchronized divisions were separated by 20h, it was possible to show that accumulation of dry weight, proteins, chlorophyll and fatty acids mainly depends on cell division, whereas starch accumulation depends on a circadian rhythm as reported previously. Our metabolomics analyses also revealed that accumulation of five (Ser, Val, Leu, Ile and Thr) of the nine free amino acids detected displayed rhythmicity, depending on cell division while Glu was 20-50 times more abundant than the other ones probably because this free amino acid serves not only for protein synthesis but also for biosynthesis of nitrogen compounds. In addition, we performed a thermodynamic-motivated theoretical approach known as 'surprisal analysis'. The results from this analysis showed that cells were close to a steady state all along the 48h of the experiment. In addition, calculation of free energy of cellular metabolites showed that the transition point, i.e. the state which immediately precedes cell division, corresponds to the most unstable stage of the cell cycle and that division is identified as the greatest drop in the free energy of metabolites. Copyright © 2015 Elsevier B.V. All rights reserved.

  9. Sharing Resources In Mobile/Satellite Communications

    NASA Technical Reports Server (NTRS)

    Yan, Tsun-Yee; Sue, Miles K.

    1992-01-01

    Report presents preliminary theoretical analysis of several alternative schemes for allocation of satellite resource among terrestrial subscribers of landmobile/satellite communication system. Demand-access and random-access approaches under code-division and frequency-division concepts compared.

  10. Label-free quantitative cell division monitoring of endothelial cells by digital holographic microscopy

    NASA Astrophysics Data System (ADS)

    Kemper, Björn; Bauwens, Andreas; Vollmer, Angelika; Ketelhut, Steffi; Langehanenberg, Patrik; Müthing, Johannes; Karch, Helge; von Bally, Gert

    2010-05-01

    Digital holographic microscopy (DHM) enables quantitative multifocus phase contrast imaging for nondestructive technical inspection and live cell analysis. Time-lapse investigations on human brain microvascular endothelial cells demonstrate the use of DHM for label-free dynamic quantitative monitoring of cell division of mother cells into daughter cells. Cytokinetic DHM analysis provides future applications in toxicology and cancer research.

  11. Levels of Professional Training of Upper-Division Students in Kuzbass Higher Educational Institutions: A Typological Analysis

    ERIC Educational Resources Information Center

    Urban, O. A.

    2008-01-01

    In this article, the data from a sociological survey serve as the basis for an analysis of the levels of professional training of the graduates of higher educational institutions in the Kuzbass region. The object of this survey consisted of upper-division students in daytime enrollment of colleges and universities in Novokuznetsk, which is not…

  12. Spire, an actin nucleation factor, regulates cell division during Drosophila heart development.

    PubMed

    Xu, Peng; Johnson, Tamara L; Stoller-Conrad, Jessica R; Schulz, Robert A

    2012-01-01

    The Drosophila dorsal vessel is a beneficial model system for studying the regulation of early heart development. Spire (Spir), an actin-nucleation factor, regulates actin dynamics in many developmental processes, such as cell shape determination, intracellular transport, and locomotion. Through protein expression pattern analysis, we demonstrate that the absence of spir function affects cell division in Myocyte enhancer factor 2-, Tinman (Tin)-, Even-skipped- and Seven up (Svp)-positive heart cells. In addition, genetic interaction analysis shows that spir functionally interacts with Dorsocross, tin, and pannier to properly specify the cardiac fate. Furthermore, through visualization of double heterozygous embryos, we determines that spir cooperates with CycA for heart cell specification and division. Finally, when comparing the spir mutant phenotype with that of a CycA mutant, the results suggest that most Svp-positive progenitors in spir mutant embryos cannot undergo full cell division at cell cycle 15, and that Tin-positive progenitors are arrested at cell cycle 16 as double-nucleated cells. We conclude that Spir plays a crucial role in controlling dorsal vessel formation and has a function in cell division during heart tube morphogenesis.

  13. Domestic work division and satisfaction in cohabiting adults: Associations with life satisfaction and self-rated health.

    PubMed

    Wagman, Petra; Nordin, Maria; Alfredsson, Lars; Westerholm, Peter J M; Fransson, Eleonor I

    2017-01-01

    The amount and perception of domestic work may affect satisfaction with everyday life, but further knowledge is needed about the relationship between domestic work division and health and well-being. To describe the division of, and satisfaction with, domestic work and responsibility for home/family in adults living with a partner. A further aim was to investigate the associations between these aspects and self-rated life satisfaction and health. Data from the Work, Lipids and Fibrinogen survey collected 2009 were used, comprising 4924 participants living with a partner. Data were analyzed using logistic regression. The majority shared domestic work and responsibility for home/family equally with their partner. However, more women conducted the majority of the domestic work and were less satisfied with its division. When both division and satisfaction with division was included in the analysis, solely satisfaction with the division and the responsibility were associated with higher odds for good life satisfaction. Regarding health, higher odds for good self-rated health were seen in those who were satisfied with their division of responsibility. The results highlight the importance of taking into account not solely the actual division of domestic work but also the satisfaction with it.

  14. The complex interface between economy and healthcare: An introductory overview for clinicians.

    PubMed

    Ottolini, Federica Liliana; Buggio, Laura; Somigliana, Edgardo; Vercellini, Paolo

    2016-12-01

    In a period of generalized economic crisis, it seems particularly appropriate to try to manage a continuing growing sector such as healthcare in the best possible way. The crucial aim of optimization of available healthcare resources is obtaining the maximum possible benefit with the minimum expenditure. This has important social implications, whether individual citizens or tax-funded national health services eventually have to pay the bill. The keyword here is efficiency, which means either, maximizing the benefit from a fixed sum of money, or minimizing the resources required for a defined benefit. In order to achieve these objectives, economic evaluation is a helpful tool. Five different types of economic evaluation exist in the health-care field: cost-minimization, cost-benefit, cost-consequences, cost-effectiveness and cost-utility analysis. The objective of this narrative review is to provide an overview of the principal methods used for economic evaluation in healthcare. Economic evaluation represents a starting point for the allocation of resources, the decision of the valuable investments and the division of budgets across different health programs. Moreover, economic evaluation allows the comparison of different procedures in terms of quality of life and life expectancy, bearing in mind that cost-effectiveness is only one of multiple facets in the decision making-process. Economic evaluation is important to critically evaluate clinical interventions and ensure that we are implementing the most cost-effective management protocols. Clinicians are called to fulfill the complex task of optimizing the use of resources, and, at the same time, improving the quality of healthcare assistance. Copyright © 2016 European Federation of Internal Medicine. Published by Elsevier B.V. All rights reserved.

  15. Interstate 73 economic impact analysis : a summary and synthesis.

    DOT National Transportation Integrated Search

    1994-01-01

    The Transportation Planning Division (TPD) of the Virginia Department of Transportation (VDOT) is currently considering seven corridors along which VDOT may build the future Interstate 73. The division describes these seven routes and their variants ...

  16. Publications - GMC 282 | Alaska Division of Geological & Geophysical

    Science.gov Websites

    DGGS GMC 282 Publication Details Title: Geochemical analysis of cuttings (11440'-11500') from the Exxon '-11500') from the Exxon Company U.S.A. OCS Y-0191-2 well: Alaska Division of Geological & Geophysical

  17. Chiasmatic and achiasmatic inverted meiosis of plants with holocentric chromosomes

    PubMed Central

    Cabral, Gabriela; Marques, André; Schubert, Veit; Pedrosa-Harand, Andrea; Schlögelhofer, Peter

    2014-01-01

    Meiosis is a specialized cell division in sexually reproducing organisms before gamete formation. Following DNA replication, the canonical sequence in species with monocentric chromosomes is characterized by reductional segregation of homologous chromosomes during the first and equational segregation of sister chromatids during the second meiotic division. Species with holocentric chromosomes employ specific adaptations to ensure regular disjunction during meiosis. Here we present the analysis of two closely related plant species with holocentric chromosomes that display an inversion of the canonical meiotic sequence, with the equational division preceding the reductional. In-depth analysis of the meiotic divisions of Rhynchospora pubera and R. tenuis reveals that during meiosis I sister chromatids are bi-oriented, display amphitelic attachment to the spindle and are subsequently separated. During prophase II, chromatids are connected by thin chromatin threads that appear instrumental for the regular disjunction of homologous non-sister chromatids in meiosis II. PMID:25295686

  18. High-speed wavelength-division multiplexing quantum key distribution system.

    PubMed

    Yoshino, Ken-ichiro; Fujiwara, Mikio; Tanaka, Akihiro; Takahashi, Seigo; Nambu, Yoshihiro; Tomita, Akihisa; Miki, Shigehito; Yamashita, Taro; Wang, Zhen; Sasaki, Masahide; Tajima, Akio

    2012-01-15

    A high-speed quantum key distribution system was developed with the wavelength-division multiplexing (WDM) technique and dedicated key distillation hardware engines. Two interferometers for encoding and decoding are shared over eight wavelengths to reduce the system's size, cost, and control complexity. The key distillation engines can process a huge amount of data from the WDM channels by using a 1 Mbit block in real time. We demonstrated a three-channel WDM system that simultaneously uses avalanche photodiodes and superconducting single-photon detectors. We achieved 12 h continuous key generation with a secure key rate of 208 kilobits per second through a 45 km field fiber with 14.5 dB loss.

  19. Spaceport Command and Control System Software Development

    NASA Technical Reports Server (NTRS)

    Glasser, Abraham

    2017-01-01

    The Spaceport Command and Control System (SCCS) is the National Aeronautics and Space Administration's (NASA) launch control system for the Orion capsule and Space Launch System, the next generation manned rocket currently in development. This large system requires a large amount of intensive testing that will properly measure the capabilities of the system. Automating the test procedures would save the project money from human labor costs, as well as making the testing process more efficient. Therefore, the Exploration Systems Division (formerly the Electrical Engineering Division) at Kennedy Space Center (KSC) has recruited interns for the past two years to work alongside full-time engineers to develop these automated tests, as well as innovate upon the current automation process.

  20. Concerted control of Escherichia coli cell division

    PubMed Central

    Osella, Matteo; Nugent, Eileen; Cosentino Lagomarsino, Marco

    2014-01-01

    The coordination of cell growth and division is a long-standing problem in biology. Focusing on Escherichia coli in steady growth, we quantify cell division control using a stochastic model, by inferring the division rate as a function of the observable parameters from large empirical datasets of dividing cells. We find that (i) cells have mechanisms to control their size, (ii) size control is effected by changes in the doubling time, rather than in the single-cell elongation rate, (iii) the division rate increases steeply with cell size for small cells, and saturates for larger cells. Importantly, (iv) the current size is not the only variable controlling cell division, but the time spent in the cell cycle appears to play a role, and (v) common tests of cell size control may fail when such concerted control is in place. Our analysis illustrates the mechanisms of cell division control in E. coli. The phenomenological framework presented is sufficiently general to be widely applicable and opens the way for rigorous tests of molecular cell-cycle models. PMID:24550446

  1. Multidose Botulinum Toxin A for Intralaryngeal Injection: A Cost Analysis.

    PubMed

    Gilbert, Mark R; Young, VyVy N; Smith, Libby J; Rosen, Clark A

    2018-01-04

    Botulinum toxin A (BtxA) injection is the mainstay treatment for laryngeal dystonias. BtxA product labeling states that reconstituted toxin should be used within 4 hours on a single patient despite several studies that have demonstrated multidose BtxA to be safe and effective. Many insurance carriers mandate the use of an outside pharmacy which necessitates a single-use approach. This study compares the cost savings of multidose BtxA for laryngeal dystonia compared to single-use. This is a retrospective review and projected cost savings analysis. Records and billing information were reviewed for patients receiving BtxA for intralaryngeal injection at a single laryngology division in 2015. Inclusion criteria included CPT 64617 or J0585; exclusion criteria included CPT 64616. The price of BtxA 100 unit vial for calculation was $670. A total of 142 patients were seen for intralaryngeal BtxA injection resulting in 337 visits over 1 year. The average BtxA dose per visit was 2.86 units with an average of 3.06 procedure visits per year. The calculated cost of BtxA treatment using a single vial approach was found to be $2,050 per patient per year. If billed instead for $7/unit with 5 units wastage charge per visit, the yearly per patient charge is $168. Single vial-use of BtxA injection thus represents a 1,118% price increase versus multidose use. When estimated for yearly prevalence of spasmodic dysphonia, multidose BtxA use would save almost $100 million annually. Multidose botulinum toxin A application utilizing per unit billing is significantly less expensive than per single-use vial billing and would save the health-care system significant amount of money without any sacrifice in safety or effectiveness. Copyright © 2018. Published by Elsevier Inc.

  2. [Mitotic behavior of centromeres in meiosis as the fertility restoration mechanism in wheat-rye amphihaploids].

    PubMed

    Loginova, D B; Silkova, O G

    2014-08-01

    The regulation of chromosomal behavior in meiosis in partly fertile wheat-rye amphihaploids was studied using the centromere specific probes pAWRC1 and Ae. tauschii pAet6-09. Comparative analysis of the probe localization patterns in mitosis, normal meiosis in wheat Triticum aestivum L. and rye Secale cereale L., and meiosis in amphihaploids was performed. The differences in the structure of centromeres in monopolar- and bipolar- oriented chromosomes were revealed. Single dense hybridization signals were observed in the diplotene and the metaphase of the first meiotic division, while hybridization signals appeared as stretched bands with diffuse structure located across the centromere region in mitosis and the second round of meiotic division. Based upon the obtained data, we used the corresponding centromere-specific probes as a tool for the analysis of chromosomal behavior in meiosis in amphihaploids. In meiocytes with three types of chromosome behavior (reductional, equational plus reductional, and equational), dense point-like hybridization signals for the pAet6-09 probe were observed for univalents with the reductional division type and stretched bands with diffuse structure for those with the equational division type. Thus, pAet6-09 probe localization patterns suggest some structural and functional specificities of centromeres in the meiosis in wheat-rye amphihaploids that reflect special regulation of chromosomal behavior during equational division. Meiocytes with true mitotic division were also observed in anthers predominantly containing meiocytes with chromosomes undergoing equational division.

  3. Interdependency of formation and localisation of the Min complex controls symmetric plastid division.

    PubMed

    Maple, Jodi; Møller, Simon G

    2007-10-01

    Plastid division represents a fundamental biological process essential for plant development; however, the molecular basis of symmetric plastid division is unclear. AtMinE1 plays a pivotal role in selection of the plastid division site in concert with AtMinD1. AtMinE1 localises to discrete foci in chloroplasts and interacts with AtMinD1, which shows a similar localisation pattern. Here, we investigate the importance of Min protein complex formation during the chloroplast division process. Dissection of the assembly of the Min protein complex and determination of the interdependency of complex assembly and localisation in planta allow us to present a model of the molecular basis of selection of the division site in plastids. Moreover, functional analysis of AtMinE1 in bacteria demonstrates the level of functional conservation and divergence of the plastidic MinE proteins.

  4. Consequence of Winning: Interdisciplinary Analysis for Deontological Perspectives of Moral Function and the Interaction with Motivation in Division I College Athletes

    ERIC Educational Resources Information Center

    Orr, Brandon

    2013-01-01

    This is a pilot study of a proposed model for examining the main and interactionist effects of achievement goal orientations on moral function and the role of perceived ability as a potential moderator in sport morality levels through cluster analysis procedures. One hundred and three elite (103) athletes participating in Division I wrestling…

  5. The Comparison Of In-Flight Pitot Static Calibration Method By Using Radio Altimeter As Reference with GPS and Tower Fly By Methods On CN235-100 MPA

    NASA Astrophysics Data System (ADS)

    Derajat; Hariowibowo, Hindawan

    2018-04-01

    The new proposed In-Flight Pitot Static Calibration Method has been carried out during Development and Qualification of CN235-100 MPA (Military Patrol Aircraft). This method is expected to reduce flight hours, less human resources required, no additional special equipment, simple analysis calculation and finally by using this method it is expected to automatically minimized operational cost. At The Indonesian Aerospace (IAe) Flight Test Center Division, the development and updating of new flight test technique and data analysis method as specially for flight physics test subject are still continued to be developed as long as it safety for flight and give additional value for the industrial side. More than 30 years, Flight Test Data Engineers at The Flight Test center Division work together with the Air Crew (Test Pilots, Co-Pilots, and Flight Test Engineers) to execute the flight test activity with standard procedure for both the existance or development test techniques and test data analysis. In this paper the approximation of mathematical model, data reduction and flight test technique of The In-Flight Pitot Static Calibration by using Radio Altimeter as reference will be described and the test results had been compared with another methods ie. By using Global Position System (GPS) and the traditional method (Tower Fly By Method) which were used previously during this Flight Test Program (Ref. [10]). The flight test data case are using CN235-100 MPA flight test data during development and Qualification Flight Test Program at Cazaux Airport, France, in June-November 2009 (Ref. [2]).

  6. Superconducting RF R&D | Technical Division

    Science.gov Websites

    Doping Contact: Anna Grassellino annag High quality factors (Q) are extremely important to accelerators with high duty factor, due to the infrastructure and operating costs of the cryogenic plant. In 2012, a process was discovered at FNAL to achieve unprecedented Q values by treating them in a high temperature

  7. 76 FR 67481 - Division of Longshore and Harbor Workers' Compensation; Proposed Renewal of Existing Collection...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-01

    ... terminated and types and amount of compensation payments. Filing of the report is mandatory, and failure to... Suspension of Compensation Benefits. OMB Number: 1240-0041. Agency Number: LS-208. Affected Public: Business... (capital/startup): $0. Total Burden Cost (operating/maintenance): $16,590. Comments submitted in response...

  8. Bridging the District-Charter Divide to Help More Students Succeed

    ERIC Educational Resources Information Center

    Lake, Robin; Yatsko, Sarah; Gill, Sean; Opalka, Alice

    2017-01-01

    In cities where public charter schools serve a large share of students, the costs of ongoing sector divisions and hostility across district and charter lines fall squarely on students and families. Exercising choice and accessing good schools in "high-choice cities" can be difficult for many families, especially some of the most…

  9. 76 FR 36468 - Approval and Promulgation of Air Quality Implementation Plans; North Carolina: Clean Smokestacks Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-22

    ... Generate Electricity and to Provide for Recovery by Electric Utilities of the Costs of Achieving Compliance... generate 25 or more megawatts of electricity: Progress Energy Carolinas, Inc. (Progress Energy) and Duke Power, a division of Duke Energy Corporation (Duke Energy). Although the emission caps apply...

  10. Focusing on the Hard parts: A Biomechanics Laboratory Exercise

    ERIC Educational Resources Information Center

    Fingerut, Jonathan; Orbe, Kristina; Flynn, Daniel; Habdas, Piotr

    2013-01-01

    As part of a biomechanics course aimed at both upper-division Biology and Physics majors, this laboratory exercise introduces students to the ingenious ways in which organisms vary the composition and form of support and defensive structures such as bone and shell to maximize their strength while minimizing the energetic cost needed to produce…

  11. Mining Permits - Division of Mining, Land, and Water

    Science.gov Websites

    are issued for a term of 1-5 years. An application for a "single year" operation costs $150 ). Federal Operators: If your operation involves federal land managed by the Bureau of Land Management (BLM issues miners the Alaska Pollutant Discharge Elimination System (APDES) General Permit. If the operation

  12. Horizontal/Vertical Stock Fund Cost Comparison

    DTIC Science & Technology

    1974-08-01

    units. Installation Supply Division account and other instal- lation operated activities: Self -Service Supply Store, Clothing Initial...installation supply operations are the Self -Service Supply Center, Clothing Sales Store, Central Issue Facility, and Clothing Initial Issue Point. Stock- age...stocks, stocks for installation operated supply activities such as the Self Service Supply Store, Clothing Sales Store and

  13. 7 CFR 11.8 - Division hearings.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... reasonable travel and subsistence costs incurred by the witness in connection with his or her appearance and... Director of rulings of a Hearing Officer are not permitted under the procedures of this part. (e) Burden of proof. The appellant has the burden of proving that the adverse decision of the agency was erroneous by...

  14. 7 CFR 11.8 - Division hearings.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... reasonable travel and subsistence costs incurred by the witness in connection with his or her appearance and... Director of rulings of a Hearing Officer are not permitted under the procedures of this part. (e) Burden of proof. The appellant has the burden of proving that the adverse decision of the agency was erroneous by...

  15. Homonyms in Context. MicroSIFT Courseware Evaluation.

    ERIC Educational Resources Information Center

    Northwest Regional Educational Lab., Portland, OR.

    THE FOLLOWING IS THE FULL TEXT OF THIS DOCUMENT (Except for the Evaluation Summary Table): VERSION: Apple II. PRODUCER: Random House, School Division, 2970 Brandywine Road, Atlanta, Georgia 30341. EVALUATION COMPLETED: June 1982 by the staff and constituents of the Portland Public Schools, Portland, Oregon. COST: Apple II and Radio Shack TRS-80…

  16. 77 FR 25750 - Notice of Lodging of Consent Decree Under the Clean Water Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-01

    ... damages and reimbursement of natural resource damage assessment costs. The Department of Justice will... Consent Decree. Comments should be addressed to the Assistant Attorney General, Environment and Natural... Section, Environment and Natural Resources Division. [FR Doc. 2012-10390 Filed 4-30-12; 8:45 am] BILLING...

  17. 77 FR 29361 - Notice of Lodging of Consent Decree Under the Comprehensive Environmental Response, Compensation...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-17

    ... (a) pay $3,812,127 to the Department of the Interior's Natural Resource Damage Assessment and... the Massachusetts Executive Office of Energy and Environmental Affairs for its assessment costs. The... General, Environment and Natural Resources Division, P.O. Box 7611, U.S. Department of Justice, Washington...

  18. Engineering Technical Support Center, Innovative Science and Technical Support for Cost-Effective Cleanups: Five Year Summary Report for 2007-2012

    EPA Science Inventory

    This report summarizes a variety of significant projects that ETSC and its colleagues in the Land Remediation and Pollution Control Division (LRPCD) have supported during the last five years. Projects have addressed an array of environmental scenarios, including remote mining co...

  19. The Mix of Military and Civilian Faculty at the United States Air Force Academy: Finding a Sustainable Balance for Enduring Success

    DTIC Science & Technology

    2013-01-01

    academic departments are as follows: The Basic Sciences Division includes the Departments of Biology, Chemistry, Computer Science, Mathematical Sciences...percent). This factor is based on actuarial estimates for the costs of the government- paid portion of health insurance under the Federal Employees

  20. 76 FR 41150 - Notice Announcing Ten-Year Regulatory Review Schedule and Request for Public Comment on the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-13

    ... in the face of changing marketplace conditions, evolving consumer behavior, and technological...) 326-2984, Attorney, Division of Enforcement, Bureau of Consumer Protection, Federal Trade Commission... continuing need for the rule or guide as well as the rule's or guide's costs and benefits to consumers and...

  1. Computer Managed Instruction at Arthur Andersen & Company: A Status Report.

    ERIC Educational Resources Information Center

    Dennis, Verl E.; Gruner, Dennis

    1992-01-01

    Computer managed instruction (CMI) based on the principle of mastery learning has been cost effective for job training in the tax division of Arthur Andersen & Company. The CMI software system, which uses computerized pretests and posttests to monitor training, has been upgraded from microcomputer use to local area networks. Success factors at…

  2. The Sixteen Division Force: Anatomy of a Decision

    DTIC Science & Technology

    1975-06-06

    blew up; there was the $500-million-plus MBr -70 tank--a "strategic mistake;" and Army experts paid $60 million for 60 atomic cannons, 57 of which...National Priorities and elsewhere" f-notably: Martin, Bink.n, Support Costs in the Defonse Budget: The Submerged One-Third (Wshingtonz 1rookings 7U.S

  3. 23 CFR 635.106 - Use of publicly owned equipment.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... publicly owned equipment is to be made available in connection with construction work to be let to contract, Federal funds may participate in the cost of such work provided the following conditions are met: (1) The...) submitted to the Division Administrator for approval. (2) The advertised specifications specify the items of...

  4. Subsea pipeline isolation systems: Reliability and costs

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Masheder, R.R.

    1995-12-31

    On the night of 6/7 July 1988 a major oil production platform known as Piper Alpha in the UK sector of the North Sea was destroyed by explosion and fire, with the loss of 167 lives. This led to the appointment of Lord Cullen, a senior Scottish Judge, to hold a Public Inquiry into the Piper Alpha Disaster. The Cullen Enquiry Report consisting of 23 chapters set out in 2 volumes, was published on 12 November 1990. One of the important conclusions drawn by Lord Cullen resulted in a recommendation for studies to be conducted to consider ways of improvingmore » the reliability and reducing the costs of SSIVs (Subsea Isolation Valves) so that it is more often reasonably practicable to install them. To address the Cullen recommendations, a joint industry study was conducted by UKOOA (United Kingdom Offshore Operators Association) and the HSE/OSD (Health and Safety Executive Offshore Safety Division) in conjunction with independent consultants. The results of the studies and the conclusions drawn by UKOOA Pipeline Valve Group and the HSE Offshore Safety Division are presented in this paper.« less

  5. Reusing Information Management Services for Recommended Decadal Study Missions to Facilitate Aerosol and Cloud Studies

    NASA Technical Reports Server (NTRS)

    Kempler, Steve; Alcott, Gary; Lynnes, Chris; Leptoukh, Greg; Vollmer, Bruce; Berrick, Steve

    2008-01-01

    NASA Earth Sciences Division (ESD) has made great investments in the development and maintenance of data management systems and information technologies, to maximize the use of NASA generated Earth science data. With information management system infrastructure in place, mature and operational, very small delta costs are required to fully support data archival, processing, and data support services required by the recommended Decadal Study missions. This presentation describes the services and capabilities of the Goddard Space Flight Center (GSFC) Earth Sciences Data and Information Services Center (GES DISC) and the reusability for these future missions. The GES DISC has developed a series of modular, reusable data management components currently in use. They include data archive and distribution (Simple, Scalable, Script-based, Science [S4] Product Archive aka S4PA), data processing (S4 Processor for Measurements aka S4PM), data search (Mirador), data browse, visualization, and analysis (Giovanni), and data mining services. Information management system components are based on atmospheric scientist inputs. Large development and maintenance cost savings can be realized through their reuse in future missions.

  6. MPRS (URBOT) commercialization

    NASA Astrophysics Data System (ADS)

    Ciccimaro, Donny; Baker, William; Hamilton, Ian; Heikkila, Leif; Renick, Joel

    2003-09-01

    The Man Portable Robotic System (MPRS) project objective was to build and deliver hardened robotic systems to the U.S. Army"s 10 Mountain Division in Fort Drum, New York. The system, specifically designed for tunnel and sewer reconnaissance, was equipped with visual and audio sensors that allowed the Army engineers to detect trip wires and booby traps before personnel entered a potentially hostile environment. The MPRS system has shown to be useful in government and military supported field exercises, but the system has yet to reach the hands of civilian users. Potential users in Law Enforcement and Border Patrol have shown a strong interest in the system, but robotic costs were thought to be prohibitive for law enforcement budgets. Through the Center for Commercialization of Advanced Technology (CCAT) program, an attempt will be made to commercialize the MPRS. This included a detailed market analysis performed to verify the market viability of the technologies. Hence, the first step in this phase is to fully define the marketability of proposed technologies in terms of actual market size, pricing and cost factors, competitive risks and/or advantages, and other key factors used to develop marketing and business plans.

  7. Bi-wavelength two dimensional chirped grating couplers for low cost WDM PON transceivers

    NASA Astrophysics Data System (ADS)

    Xu, Lin; Chen, Xia; Li, Chao; Tsang, Hon Ki

    2011-04-01

    We propose and demonstrate a bi-wavelength two dimensional (2D) waveguide grating coupler on silicon-on-insulator which has efficient coupling of optical light with two-wavelength bands independently between standard optical single mode fibers and nanophotonic waveguides. The details of design are described and the measurement results as well as system performance are experimentally characterized. The bi-wavelength grating coupler can be used as wavelength-division-multiplexing (WDM) splitter/combiner for monolithically silicon integrated transceivers, potentially meeting the low cost requirements for future WDM passive optical network (PON).

  8. Self-healing ring-based WDM-PON

    NASA Astrophysics Data System (ADS)

    Zhou, Yang; Gan, Chaoqin; Zhu, Long

    2010-05-01

    In this paper, a survivable ring-based wavelength-division-multiplexing (WDM)-passive optical network (PON) for fiber protection is proposed. Protections for feeder fiber and distributed fiber are independent in the scheme. Optical line terminal (OLT) and optical network units (ONUs) can automatically switch to protection link when fiber failure occurs. Protection distributed fiber is not required in the scheme. Cost-effective components are used in ONUs to minimize costs of network. A simulation study is performed to demonstrate the scheme. Its result shows good performance of upstream and downstream signals.

  9. Personnel and Cargo Transport in Antarctica: Analysis of Current U.S. Transport System

    DTIC Science & Technology

    1991-03-01

    George L. Blaisdell March 1991 ,i . . 1 U - I I Prepared for DIVISION OF DOLAR PROGRAMS NATIONAL SCIENCE FOUNDATION Approved for public release...Engineering Division, U.S. Army Cold Regions Research and Engineering Laboratory. Funding was provided by the Division of Polar Programs, National Science Foundation . A...Current U.S. Transport System GEORGE L. BLAISDELL INTRODUCTION The National Science Foundation (NSF), operator of the U.S. Antarctic program, has

  10. Characterization of dependencies between growth and division in budding yeast

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mayhew, Michael B.; Iversen, Edwin S.; Hartemink, Alexander J.

    Cell growth and division are processes vital to the proliferation and development of life. Coordination between these two processes has been recognized for decades in a variety of organisms. In the budding yeast Saccharomyces cerevisiae, this coordination or ‘size control’ appears as an inverse correlation between cell size and the rate of cell-cycle progression, routinely observed in G1 prior to cell division commitment. Beyond this point, cells are presumed to complete S/G 2/M at similar rates and in a size-independent manner. As such, studies of dependence between growth and division have focused on G1. Moreover, in unicellular organisms, coordination betweenmore » growth and division has commonly been analyzed within the cycle of a single cell without accounting for correlations in growth and division characteristics between cycles of related cells. In a comprehensive analysis of three published time-lapse microscopy datasets, we analyze both intra- and inter-cycle dependencies between growth and division, revisiting assumptions about the coordination between these two processes. Interestingly, we find evidence (1) that S/G 2/M durations are systematically longer in daughters than in mothers, (2) of dependencies between S/G2/M and size at budding that echo the classical G1 dependencies, and, (3) in contrast with recent bacterial studies, of negative dependencies between size at birth and size accumulated during the cell cycle. In addition, we develop a novel hierarchical model to uncover inter-cycle dependencies, and we find evidence for such dependencies in cells growing in sugar-poor environments. Our analysis highlights the need for experimentalists and modelers to account for new sources of cell-to-cell variation in growth and division, and our model provides a formal statistical framework for the continued study of dependencies between biological processes.« less

  11. Characterization of dependencies between growth and division in budding yeast

    DOE PAGES

    Mayhew, Michael B.; Iversen, Edwin S.; Hartemink, Alexander J.

    2017-02-01

    Cell growth and division are processes vital to the proliferation and development of life. Coordination between these two processes has been recognized for decades in a variety of organisms. In the budding yeast Saccharomyces cerevisiae, this coordination or ‘size control’ appears as an inverse correlation between cell size and the rate of cell-cycle progression, routinely observed in G1 prior to cell division commitment. Beyond this point, cells are presumed to complete S/G 2/M at similar rates and in a size-independent manner. As such, studies of dependence between growth and division have focused on G1. Moreover, in unicellular organisms, coordination betweenmore » growth and division has commonly been analyzed within the cycle of a single cell without accounting for correlations in growth and division characteristics between cycles of related cells. In a comprehensive analysis of three published time-lapse microscopy datasets, we analyze both intra- and inter-cycle dependencies between growth and division, revisiting assumptions about the coordination between these two processes. Interestingly, we find evidence (1) that S/G 2/M durations are systematically longer in daughters than in mothers, (2) of dependencies between S/G2/M and size at budding that echo the classical G1 dependencies, and, (3) in contrast with recent bacterial studies, of negative dependencies between size at birth and size accumulated during the cell cycle. In addition, we develop a novel hierarchical model to uncover inter-cycle dependencies, and we find evidence for such dependencies in cells growing in sugar-poor environments. Our analysis highlights the need for experimentalists and modelers to account for new sources of cell-to-cell variation in growth and division, and our model provides a formal statistical framework for the continued study of dependencies between biological processes.« less

  12. Characterization of dependencies between growth and division in budding yeast

    PubMed Central

    Iversen, Edwin S.; Hartemink, Alexander J.

    2017-01-01

    Cell growth and division are processes vital to the proliferation and development of life. Coordination between these two processes has been recognized for decades in a variety of organisms. In the budding yeast Saccharomyces cerevisiae, this coordination or ‘size control’ appears as an inverse correlation between cell size and the rate of cell-cycle progression, routinely observed in G1 prior to cell division commitment. Beyond this point, cells are presumed to complete S/G2/M at similar rates and in a size-independent manner. As such, studies of dependence between growth and division have focused on G1. Moreover, in unicellular organisms, coordination between growth and division has commonly been analysed within the cycle of a single cell without accounting for correlations in growth and division characteristics between cycles of related cells. In a comprehensive analysis of three published time-lapse microscopy datasets, we analyse both intra- and inter-cycle dependencies between growth and division, revisiting assumptions about the coordination between these two processes. Interestingly, we find evidence (i) that S/G2/M durations are systematically longer in daughters than in mothers, (ii) of dependencies between S/G2/M and size at budding that echo the classical G1 dependencies, and (iii) in contrast with recent bacterial studies, of negative dependencies between size at birth and size accumulated during the cell cycle. In addition, we develop a novel hierarchical model to uncover inter-cycle dependencies, and we find evidence for such dependencies in cells growing in sugar-poor environments. Our analysis highlights the need for experimentalists and modellers to account for new sources of cell-to-cell variation in growth and division, and our model provides a formal statistical framework for the continued study of dependencies between biological processes. PMID:28228543

  13. Characterization of dependencies between growth and division in budding yeast.

    PubMed

    Mayhew, Michael B; Iversen, Edwin S; Hartemink, Alexander J

    2017-02-01

    Cell growth and division are processes vital to the proliferation and development of life. Coordination between these two processes has been recognized for decades in a variety of organisms. In the budding yeast Saccharomyces cerevisiae , this coordination or 'size control' appears as an inverse correlation between cell size and the rate of cell-cycle progression, routinely observed in G 1 prior to cell division commitment. Beyond this point, cells are presumed to complete S/G 2 /M at similar rates and in a size-independent manner. As such, studies of dependence between growth and division have focused on G 1 Moreover, in unicellular organisms, coordination between growth and division has commonly been analysed within the cycle of a single cell without accounting for correlations in growth and division characteristics between cycles of related cells. In a comprehensive analysis of three published time-lapse microscopy datasets, we analyse both intra- and inter-cycle dependencies between growth and division, revisiting assumptions about the coordination between these two processes. Interestingly, we find evidence (i) that S/G 2 /M durations are systematically longer in daughters than in mothers, (ii) of dependencies between S/G 2 /M and size at budding that echo the classical G 1 dependencies, and (iii) in contrast with recent bacterial studies, of negative dependencies between size at birth and size accumulated during the cell cycle. In addition, we develop a novel hierarchical model to uncover inter-cycle dependencies, and we find evidence for such dependencies in cells growing in sugar-poor environments. Our analysis highlights the need for experimentalists and modellers to account for new sources of cell-to-cell variation in growth and division, and our model provides a formal statistical framework for the continued study of dependencies between biological processes. © 2017 The Author(s).

  14. High Reliability and the Evaluation of ATC System Configuration by Communizing Resources

    NASA Astrophysics Data System (ADS)

    Yamamoto, Masanori

    Automatic Train Control (ATC) in the railway signalling system is required high safety, high availability, reduction of unit, energy saving and cost reduction. This paper described the resources communization redundancy of the ATC system that shared the redundant units in preparation for common use units in order to accommodate with this issue by keeping safety and availability in the same level of conventional ATC. It was evaluated on N+2 redundant system which established 2 spares for the common use system N piece in transmission division. It was done the safety evaluation of the N+2 redundant system by way of hazard analysis of FTA method and safety issue was confirmed by FMEA. The new redundant system concludes that 19% of downsizing and 36% of the energy saving are surely possible.

  15. Cost-effective WDM-PON Delivering Up/Down-stream Data on a Single Wavelength Using Soliton Pulse

    NASA Astrophysics Data System (ADS)

    Tawade, Laxman

    2013-06-01

    This paper presents wavelength division multiplexing passive optical network (WDM-PON) system delivering downstream 2.5 Gbit/s data and upstream 1 Gbit/s data on a single wavelength using pulse source is mode locked laser which generating a single pulse of "sech" shape with specified power and width i.e. soliton pulse. The optical source for downstream data and upstream data is sech pulse generator at central office and reflective semiconductor optical amplifier (RSOA) at each optical network unit. We also investigate analysis of backscattered optical signal for upstream data and downstream data simultaneously. Bit error rate, Q-Factor were measured to demonstrate the proposed scheme. In this paper Long reach aspects of an access network is investigated using single channel scenario.

  16. Impact of Requirements Quality on Project Success or Failure

    NASA Astrophysics Data System (ADS)

    Tamai, Tetsuo; Kamata, Mayumi Itakura

    We are interested in the relationship between the quality of the requirements specifications for software projects and the subsequent outcome of the projects. To examine this relationship, we investigated 32 projects started and completed between 2003 and 2005 by the software development division of a large company in Tokyo. The company has collected reliable data on requirements specification quality, as evaluated by software quality assurance teams, and overall project performance data relating to cost and time overruns. The data for requirements specification quality were first converted into a multiple-dimensional space, with each dimension corresponding to an item of the recommended structure for software requirements specifications (SRS) defined in IEEE Std. 830-1998. We applied various statistical analysis methods to the SRS quality data and project outcomes.

  17. Cost-effectiveness and the socialization of health care.

    PubMed

    Musgrove, P

    1995-01-01

    The more health care is socialized, the more cost-effectiveness is an appropriate criterion for expenditure. Utility-maximizing individuals, facing divisibility of health care purchases and declining marginal health gains, and complete information about probable health improvements, should buy health care according to its cost-effectiveness. Absent these features, individual health spending will not be cost-effective; and in any case, differences in personal utilities and risk aversion will not lead to the same ranking of health care interventions for everyone. Private insurance frees consumers from concern for cost, which undermines cost-effectiveness, but lets them emphasize effectiveness, which favors value for money. This is most important for costly and cost-effective interventions, especially for poor people. Cost-effectiveness is more appropriate and easier to achieve under second-party insurance. More complete socialization of health care, via public finance, can yield greater efficiency by making insurance compulsory. Cost-effectiveness is also more attractive when taxpayers subsidize others' care: needs (effectiveness) take precedence over wants (utility). The gain in effectiveness may be greater, and the welfare loss from Pareto non-optimality smaller, in poor countries than in rich ones.

  18. Information seeking for making evidence-informed decisions: a social network analysis on the staff of a public health department in Canada.

    PubMed

    Yousefi-Nooraie, Reza; Dobbins, Maureen; Brouwers, Melissa; Wakefield, Patricia

    2012-05-16

    Social network analysis is an approach to study the interactions and exchange of resources among people. It can help understanding the underlying structural and behavioral complexities that influence the process of capacity building towards evidence-informed decision making. A social network analysis was conducted to understand if and how the staff of a public health department in Ontario turn to peers to get help incorporating research evidence into practice. The staff were invited to respond to an online questionnaire inquiring about information seeking behavior, identification of colleague expertise, and friendship status. Three networks were developed based on the 170 participants. Overall shape, key indices, the most central people and brokers, and their characteristics were identified. The network analysis showed a low density and localized information-seeking network. Inter-personal connections were mainly clustered by organizational divisions; and people tended to limit information-seeking connections to a handful of peers in their division. However, recognition of expertise and friendship networks showed more cross-divisional connections. Members of the office of the Medical Officer of Health were located at the heart of the department, bridging across divisions. A small group of professional consultants and middle managers were the most-central staff in the network, also connecting their divisions to the center of the information-seeking network. In each division, there were some locally central staff, mainly practitioners, who connected their neighboring peers; but they were not necessarily connected to other experts or managers. The methods of social network analysis were useful in providing a systems approach to understand how knowledge might flow in an organization. The findings of this study can be used to identify early adopters of knowledge translation interventions, forming Communities of Practice, and potential internal knowledge brokers.

  19. Petroleum marketing monthly, September 1994

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    The Petroleum Marketing Monthly (PMM) provides information and statistical data on a variety of crude oils and refined petroleum products. The publication presents statistics on crude oil costs and refined petroleum product sales for use by industry, government, private sector analysts, educational institutions, and consumers. Data on crude oil include the domestic first purchase price, the f.o.b. and landed cost of imported crude oil, and the refiners` acquisition cost of crude oil. Refined petroleum product sales data include motor gasoline, distillates, residuals, aviation fuels, kerosene, and propane. The Petroleum Marketing Division, Office of Oil and Gas, Energy Information Administration ensuresmore » the accuracy, quality, and confidentiality of the published data in the Petroleum Marketing Monthly.« less

  20. Evolution of division of labor: emergence of different activities among group members.

    PubMed

    Nakahashi, Wataru; Feldman, Marcus W

    2014-05-07

    The division of labor is an important component of the organization of human society. However, why this division evolved in hominids requires further investigation. Archeological evidence suggests that it appeared after the emergence of Homo sapiens and contributed to the great success of our species. We develop a mathematical model to investigate under what conditions division of labor should evolve. We assume two types of resources the acquisition of which demands different skills, and study the evolution of the strategy that an individual should use to divide its lifetime into learning and using each skill. We show that division of labor likely evolves when group size is large, skill learning is important for acquiring resources, and there is food sharing within a group. We also investigate division of labor by gender under the assumption that the genders have different efficiencies in acquiring each resource. We show that division of labor by gender likely evolves when skill learning is important and the difference in efficiencies between genders in acquiring resources is large. We discuss how the results of our analysis might apply to the evolution of division of labor in hominids. Copyright © 2014 Elsevier Ltd. All rights reserved.

  1. Automated cell tracking identifies mechanically oriented cell divisions during Drosophila axis elongation.

    PubMed

    Wang, Michael F Z; Hunter, Miranda V; Wang, Gang; McFaul, Christopher; Yip, Christopher M; Fernandez-Gonzalez, Rodrigo

    2017-04-01

    Embryos extend their anterior-posterior (AP) axis in a conserved process known as axis elongation. Drosophila axis elongation occurs in an epithelial monolayer, the germband, and is driven by cell intercalation, cell shape changes, and oriented cell divisions at the posterior germband. Anterior germband cells also divide during axis elongation. We developed image analysis and pattern-recognition methods to track dividing cells from confocal microscopy movies in a generally applicable approach. Mesectoderm cells, forming the ventral midline, divided parallel to the AP axis, while lateral cells displayed a uniform distribution of division orientations. Mesectoderm cells did not intercalate and sustained increased AP strain before cell division. After division, mesectoderm cell density increased along the AP axis, thus relieving strain. We used laser ablation to isolate mesectoderm cells from the influence of other tissues. Uncoupling the mesectoderm from intercalating cells did not affect cell division orientation. Conversely, separating the mesectoderm from the anterior and posterior poles of the embryo resulted in uniformly oriented divisions. Our data suggest that mesectoderm cells align their division angle to reduce strain caused by mechanical forces along the AP axis of the embryo. © 2017. Published by The Company of Biologists Ltd.

  2. TOLUENE DOSE-EFFECT META ANALYSIS AND IMPORTANCE OF EFFECTS

    EPA Science Inventory

    TOLUENE DOSE-EFFECT META ANALYSES AND IMPORTANCE OF EFFECTS
    Benignus, V.A., Research Psychologist, ORD, NHEERL, Human Studies Division,
    919-966-6242, benignus.vernon@epa.gov
    Boyes, W.K., Supervisory Health Scientist, ORD, NHEERL, Neurotoxicology Division
    919-541-...

  3. Rapid phylogenetic dissection of prokaryotic community structure in tidal flat using pyrosequencing.

    PubMed

    Kim, Bong-Soo; Kim, Byung Kwon; Lee, Jae-Hak; Kim, Myungjin; Lim, Young Woon; Chun, Jongsik

    2008-08-01

    Dissection of prokaryotic community structure is prerequisite to understand their ecological roles. Various methods are available for such a purpose which amplification and sequencing of 16S rRNA genes gained its popularity. However, conventional methods based on Sanger sequencing technique require cloning process prior to sequencing, and are expensive and labor-intensive. We investigated prokaryotic community structure in tidal flat sediments, Korea, using pyrosequencing and a subsequent automated bioinformatic pipeline for the rapid and accurate taxonomic assignment of each amplicon. The combination of pyrosequencing and bioinformatic analysis showed that bacterial and archaeal communities were more diverse than previously reported in clone library studies. Pyrosequencing analysis revealed 21 bacterial divisions and 37 candidate divisions. Proteobacteria was the most abundant division in the bacterial community, of which Gamma-and Delta-Proteobacteria were the most abundant. Similarly, 4 archaeal divisions were found in tidal flat sediments. Euryarchaeota was the most abundant division in the archaeal sequences, which were further divided into 8 classes and 11 unclassified euryarchaeota groups. The system developed here provides a simple, in-depth and automated way of dissecting a prokaryotic community structure without extensive pretreatment such as cloning.

  4. Orthopaedics injuries in male professional football players in Brazil: a prospective comparison between two divisions

    PubMed Central

    Arliani, Gustavo Gonçalves; Lara, Paulo Henrique Schmidt; Astur, Diego Costa; Pedrinelli, André; Pagura, Jorge Roberto; Cohen, Moisés

    2017-01-01

    Summary Background Football is a high-speed contact sport and the risk of injury is high. The objective of this study was to compare the two main divisions (A1 and A2) of the São Paulo Football Championship and to perform a correlation analysis of the variables studied. Methods A prospective study was conducted using an electronic questionnaire previously developed by the Medical Committee of the São Paulo Football Federation. The questionnaire was sent to the doctors of the teams playing in the A1 and A2 divisions of the São Paulo Football Championship after each round. Setting: 2016 São Paulo Football Championship. Results The comparison of divisions A1 and A2 showed few significant differences among the various variables analysed in this study. The only significant differences were for right-side involvement in division A1 (p=0.044) and morning matches in division A2 (p<0.001). The correlation analysis of the variables studied showed expected associations, including sprains with a higher rate of need for surgery, ultrasound with muscle strains and moderate severity (8–28 days lost) with muscle strains. Conclusion Despite the differences between the two divisions regarding budgets and team characteristics, there was a little difference in the variables analysed and there were associations such as sprains with a higher rate of need for surgery, ultrasound with muscle strains and moderate severity (8–28 days lost) with muscle strains. Level of evidence II b, individual cohort study. PMID:29387647

  5. Providing Mailing Cost Reimbursements: The Effect on Reporting Timeliness of Sexually Transmitted Diseases in Virginia.

    PubMed

    Vasiliu, Oana E; Stover, Jeffrey A; Mays, Marissa J E; Bissette, Jennifer M; Dolan, Carrie B; Sirbu, Corina M

    2009-01-01

    We investigated the effect of providing mailing cost reimbursements to local health departments on the timeliness of the reporting of sexually transmitted diseases (STDs) in Virginia. The Division of Disease Prevention, Virginia Department of Health, provided mailing cost reimbursements to 31 Virginia health districts from October 2002 to December 2004. The difference (in days) between the diagnosis date (or date the STD paperwork was initiated) and the date the case/STD report was entered into the STD surveillance database was used in a negative binomial regression model against time (as divided into three periods-before, during, and after reimbursement) to estimate the effect of providing mailing cost reimbursements on reporting timeliness. We observed significant decreases in the number of days between diagnosis and reporting of a case, which were sustained after the reimbursement period ended, in 25 of the 31 health districts included in the analysis. We observed a significant initial decrease (during the reimbursement period) followed by a significant increase in the after-reimbursement phase in one health district. Two health districts had a significant initial decrease, while one health district had a significant decrease in reporting timeliness in the period after reimbursement. Two health districts showed no significant changes in the number of days to report to the central office. Providing reimbursements for mailing costs was statistically associated with improved STD reporting timeliness in almost all of Virginia's health districts. Sustained improvement after the reimbursement period ended is likely indicative of improved local health department reporting habits.

  6. Enhancement on infectious diseases nursing plan information system.

    PubMed

    Yeh, Mei-Lin; Hao, Te-Hui; Hsu, Chien-Yeh

    2009-01-01

    Based on researches, the most time-consuming nursing activities, in teaching hospital, are: room patrols, the blood pressure survey, the body temperature pulse breath survey, the nursing record maintenance. The nursing record is one way to communicate data. It can allow the medical service team to understand what measures the nursing staff once did for sickness, as well as responses from sickness. Nevertheless, it is the key component to utilize the record with a clinical nursing plan, so as to provide a proficient health management. Since the maintenance of nursing plan is costly and time-consuming, therefore, it is essential to establish the nursing plan information system, which can effectively promote the nursing quality. This research main body comes from one infectious disease division nursing plan information system, which was developed in 1992, and its data base covers entire courtyard compatibility and various faculties characteristic nursing plan. The nursing staff often complained that this system is not user-friendly, its contents are not comprehensive, and sometimes it does not let staff choose the right diagnosis. Therefore this research is based on history analysis and the questionnaire survey procedure first, the infectious disease nursing plan use number of times, the frequency and the project content, then by the literature scientific theory and result of the improvement group discussion together. The original 38 infectious disease division nursing plan will be expanded to 45 nursing plans. Moreover, the common 38 infectious disease code (ICD-9), and its corresponding diagnosis items, shall automatically appear in the disease diagnose code field, so it would be better off for the nursing staff to set up the nursing plan efficiently. Infectious disease division nursing plan information system utilization ratio is promoted 9.6-folds, according to research outcome. Each task consumes 3.68 minutes beforehand-including computer program operation, the printing of nursing plan, and now it turned out that it shall not take more than 3.08 minutes. The time efficiency is raised by 17% (0.6 minute). Yet only 17% of the users are satisfied with it before, and now 74% nursing staffs are happy with the new tool.Therefore, it shall not only improve our service quality, but also save labor cost by using this information supplementary system.

  7. Cost-effectiveness analysis of the introduction of the human papillomavirus vaccine in Honduras.

    PubMed

    Aguilar, Ida Berenice Molina; Mendoza, Lourdes Otilia; García, Odalys; Díaz, Iris; Figueroa, Jacqueline; Duarte, Rosa María; Perdomo, Gabriel; Garcia, Ana Gabriela Felix; Janusz, Cara Bess

    2015-05-07

    Cervical cancer is the leading cause of cancer deaths in Honduras. With the availability of a vaccine to prevent human papillomavirus (HPV), the causative agent for cervical cancer, the Honduran Secretary of Health undertook a cost-effectiveness analysis of introducing the HPV vaccine to support their national decision-making process. A national multidisciplinary team conducted this analysis with the CERVIVAC model, developed by the London School of Hygiene and Tropical Medicine in collaboration with the Pan American Health Organization's ProVac Initiative. The cumulative costs and health benefits of introducing the HPV vaccine were assessed over the lifetime of one single cohort of 11-year-old girls. We assumed a three-dose series with 95% vaccination coverage of the cohort using a mixture of school-based and facility-based delivery. To estimate national cervical cancer cases and deaths, we used United Nations demographic projections and GLOBOCAN estimates based on registry data from El Salvador, Guatemala, and Nicaragua. Based on estimates from the World Health Organization (WHO) and the Division of Intensified Cooperation with Countries (ICO), we assumed that 70% of cervical cancer would be due to vaccine types HPV16 and HPV18. We used a vaccine dose price of US$ 13.45 and evidence from the scientific literature to estimate vaccine effectiveness. National information was used to estimate health service utilization and costs of cervical cancer treatment. All costs and health benefits were discounted at 3%. Upon fully vaccinating 86,906 11-year old girls, 2250 (undiscounted) cervical cancer cases and 1336 (undiscounted) deaths would be prevented over the lifetime of the cohort. After discounting future health benefits at 3% per year, the equivalent cases and deaths prevented were 421 and 170. HPV vaccination is estimated to cost around US$ 5 million per vaccinated cohort, but this would be offset by around US$ 1 million in avoided costs borne by the government to treat cervical cancer. Furthermore, 4349 discounted disability adjusted life years (DALYs) could be avoided at a cost of US$ 926 per DALY avoided, making HPV vaccination in Honduras a highly cost-effective intervention. The net cost of HPV vaccination per DALY avoided is less than the WHO threshold for cost-effectiveness. However, at a cost of around US$ 5 million per vaccinated cohort, an important element to consider in this discussion is the budgetary implications that the introduction of the HPV vaccine would cause for the country. When comparing the costs and benefits of HPV vaccine introduction in Honduras, it is clear that this intervention would be highly cost-effective and that the intervention would greatly reduce cervical cancer disease. For these reasons, it is in the country's best interest to explore financing opportunities that could support the vaccine's introduction. Copyright © 2014 Elsevier Ltd. All rights reserved.

  8. Fiber-Bragg-Grating-Based Optical Code-Division Multiple Access Passive Optical Network Using Dual-Baseband Modulation Scheme

    NASA Astrophysics Data System (ADS)

    Lin, Wen-Piao; Wu, He-Long

    2005-08-01

    We propose a fiber-Bragg-grating (FBG)-based optical code-division multiple access passive optical network (OCDMA-PON) using a dual-baseband modulation scheme. A mathematical model is developed to study the performance of this scheme. According to the analyzed results, this scheme can allow a tolerance of the spectral power distortion (SPD) ratio of 25% with a bit error rate (BER) of 10-9 when the modified pseudorandom noise (PN) code length is 16. Moreover, we set up a simulated system to evaluate the baseband and radio frequency (RF) band transmission characteristics. The simulation results demonstrate that our proposed OCDMA-PON can provide a cost-effective and scalable fiber-to-the-home solution.

  9. Colorless ONU implementation for WDM-PON using direct-detection optical OFDM

    NASA Astrophysics Data System (ADS)

    Feng, Min; Luo, Qing-long; Bai, Cheng-lin

    2013-03-01

    A novel architecture for the colorless optical network unit (ONU) is proposed and experimentally demonstrated with direct-detection optical orthogonal frequency division multiplexing (DDO-OFDM). In this architecture, polarization-division multiplexing is used to reduce the cost at ONU. In optical line terminal (OLT), quadrature amplitude modulation (QAM) intensity-modulated OFDM signal with x-polarization at 10 Gbit/s is transmitted as downstream. At each ONU, the optical OFDM signal is demodulated with direct detection, and γ-polarization signal is modulated for upstream on-off keying (OOK) data at 5 Gbit/s. Simulation results show that the power penalty is negligible for both optical OFDM downstream and the on-off keying upstream signals after over 50 km single-mode fiber (SMF) transmission.

  10. Evaluation of three electronic report processing systems for preparing hydrologic reports of the U.S Geological Survey, Water Resources Division

    USGS Publications Warehouse

    Stiltner, G.J.

    1990-01-01

    In 1987, the Water Resources Division of the U.S. Geological Survey undertook three pilot projects to evaluate electronic report processing systems as a means to improve the quality and timeliness of reports pertaining to water resources investigations. The three projects selected for study included the use of the following configuration of software and hardware: Ventura Publisher software on an IBM model AT personal computer, PageMaker software on a Macintosh computer, and FrameMaker software on a Sun Microsystems workstation. The following assessment criteria were to be addressed in the pilot studies: The combined use of text, tables, and graphics; analysis of time; ease of learning; compatibility with the existing minicomputer system; and technical limitations. It was considered essential that the camera-ready copy produced be in a format suitable for publication. Visual improvement alone was not a consideration. This report consolidates and summarizes the findings of the electronic report processing pilot projects. Text and table files originating on the existing minicomputer system were successfully transformed to the electronic report processing systems in American Standard Code for Information Interchange (ASCII) format. Graphics prepared using a proprietary graphics software package were transferred to all the electronic report processing software through the use of Computer Graphic Metafiles. Graphics from other sources were entered into the systems by scanning paper images. Comparative analysis of time needed to process text and tables by the electronic report processing systems and by conventional methods indicated that, although more time is invested in creating the original page composition for an electronically processed report , substantial time is saved in producing subsequent reports because the format can be stored and re-used by electronic means as a template. Because of the more compact page layouts, costs of printing the reports were 15% to 25% less than costs of printing the reports prepared by conventional methods. Because the largest report workload in the offices conducting water resources investigations is preparation of Water-Resources Investigations Reports, Open-File Reports, and annual State Data Reports, the pilot studies only involved these projects. (USGS)

  11. Design, modeling, and analysis of multi-channel demultiplexer/demodulator

    NASA Technical Reports Server (NTRS)

    Lee, David D.; Woo, K. T.

    1991-01-01

    Traditionally, satellites have performed the function of a simple repeater. Newer data distribution satellite architectures, however, require demodulation of many frequency division multiplexed uplink channels by a single demultiplexer/demodulator unit, baseband processing and routing of individual voice/data circuits, and remodulation into time division multiplexed (TDM) downlink carriers. The TRW MCDD (Multichannel Demultiplexer/Multirate Demodulator) operates on a 37.4 MHz composite input signal. Individual channel data rates are either 64 Kbps or 2.048 Mbps. The wideband demultiplexer divides the input signal into 1.44 MHz segments containing either a single 2.048 Mbps channel or thirty two 64 Kbps channels. In the latter case, the narrowband demultiplexer further divides the single 1.44 MHz wideband channel into thirty two 45 KHz narrowband channels. With this approach the time domain Fast Fourier Transformation (FFT) channelizer processing capacity is matched well to the bandwidth and number of channels to be demultiplexed. By using a multirate demodulator fewer demodulators are required while achieving greater flexibility. Each demodulator can process a wideband channel or thirty two narrowband channels. Either all wideband channels, a mixture of wideband and narrowband channels, or all narrowband channels can be demodulated. The multirate demodulator approach also has lower nonrecurring costs since only one design and development effort is needed. TRW has developed a proof of concept (POC) model which fully demonstrates the signal processing fuctions of MCDD. It is capable of processing either three 2.048 Mbps channels or two 2.048 Mbps channels and thirty two 64 Kbps channels. An overview of important MCDD system engineering issues is presented as well as discussion on some of the Block Oriented System Simulation analyses performed for design verification and selection of operational parameters of the POC model. Systems engineering analysis of the POC model confirmed that the MCDD concepts are not only achievable but also balance the joint goals of minimizing on-board complexity and cost of ground equipment, while retaining the flexibility needed to meet a wide range of system requirements.

  12. Integrated Safety Analysis Tiers

    NASA Technical Reports Server (NTRS)

    Shackelford, Carla; McNairy, Lisa; Wetherholt, Jon

    2009-01-01

    Commercial partnerships and organizational constraints, combined with complex systems, may lead to division of hazard analysis across organizations. This division could cause important hazards to be overlooked, causes to be missed, controls for a hazard to be incomplete, or verifications to be inefficient. Each organization s team must understand at least one level beyond the interface sufficiently enough to comprehend integrated hazards. This paper will discuss various ways to properly divide analysis among organizations. The Ares I launch vehicle integrated safety analyses effort will be utilized to illustrate an approach that addresses the key issues and concerns arising from multiple analysis responsibilities.

  13. A COMPARATIVE ANALYSIS OF THE RESEARCH UTILIZATION PROCESS.

    ERIC Educational Resources Information Center

    LIPPITT, RONALD; AND OTHERS

    A SUGGESTED MODEL FOR ADEQUATE DISSEMINATION OF RESEARCH FINDINGS CONSIDERS FOUR PRIMARY BARRIERS TO EFFECTIVE COMMUNICATION--(1) DIVISION OF PERSONNEL LABOR INTO TASK ROLES, (2) INSTITUTIONAL DISTINCTIONS, (3) DEVELOPMENT OF PROFESSIONAL REFERENCE GROUPS, AND (4) GEOGRAPHICAL DIVISIONS. SUGGESTED SOLUTIONS INCLUDE LINKING SYSTEMS AND ROLES,…

  14. 29 CFR 531.7 - Request for review of tip credit.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Request for review of tip credit. 531.7 Section 531.7 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR REGULATIONS WAGE PAYMENTS UNDER THE FAIR LABOR STANDARDS ACT OF 1938 Determinations of âReasonable Costâ and âFair Valueâ...

  15. 77 FR 42535 - Self-Regulatory Organizations; NYSE MKT LLC; Notice of Filing and Immediate Effectiveness of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-19

    ... also notes that the economics literature confirms that there is no way to allocate common costs between... generally Mark Hirschey, Fundamentals of Managerial Economics, at 600 (2009) (``It is important to note... Railway Rates,'' Quarterly Journal of Economics V(4) 438, 465 (July 1891) (``Yet, surely, the division is...

  16. 33 CFR 209.140 - Operations of the Corps of Engineers under the Federal Power Act.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... directing studies to be made. In the case of an application for permit or license for an unconstructed... required to insure coordination of the applicant's studies with the Division or District Engineer in cases... studies, will when requested by the Chief of Engineers submit an estimate of the cost of the investigation...

  17. Loglines. September-October 2013

    DTIC Science & Technology

    2013-10-01

    comes to new technologies that can improve product performance for our customers and reduce costs, storage and transportation requirements and...in. DLA Strategic Materials is partnering with academic institutions such as Penn State, Yale and MIT to research storage and transportation of...direct delivery contracting office, inventory and requirements division, and the transportation /tankers group, Domen said. Internal support is also

  18. Gamification and Smart Feedback: Experiences with a Primary School Level Math App

    ERIC Educational Resources Information Center

    Kickmeier-Rust, Michael D.; Hillemann, Eva-C.; Albert, Dietrich

    2014-01-01

    Gamification is a recent trend in the field of game-based learning that accounts for development effort, costs, and effectiveness concerns of games. Another trend in educational technology is learning analytics and formative feedback. In the context of a European project the developed a light weight tool for learning and practicing divisions named…

  19. Athletics in the Academic Marketplace: Using Revenue Theory of Cost to Compare Trends in Athletic Coaching Salaries and Instructional Salaries and Tuition

    ERIC Educational Resources Information Center

    Hirko, Scott; Suggs, David Welch; Orleans, Jeffrey H.

    2013-01-01

    This study reviewed publicly available institutional financial and participation reports at the highest level of athletic competition, National Collegiate Athletic Association (NCAA) Division I. Institutions were grouped by NCAA subdivision status, athletic conference, flagship status, football Bowl Championship Series automatic qualifying status,…

  20. Using Combat Camera Still Imagery Products To Improve U.S. Strategic Communications

    DTIC Science & Technology

    2014-04-01

    seven local farmers on a split-cost basis and teaches them how to properly raise, maintain and manage egg-laying poultry . (U.S. Navy photo by Petty...Infantry Division, Military Policeman Sgt. Thomas Dwyer of Ft. River, N.J., laughs with Iraqi children while on a patrol in the Muhalla 513 neighborhood

  1. 75 FR 64352 - Notice of Lodging of Consent Decree Under the Comprehensive Environmental Response, Compensation...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-19

    ... and state trustees nearly $1,200,000 of past natural resource damages assessment costs, (2) perform... and Environmental Assessment for the Bayou Verdine Site, and (3) pay an additional sum of $750,000... Environment and Natural Resources Division, U.S. Department of Justice, and either e-mailed to pubcomment-ees...

  2. 78 FR 6131 - Notice of Lodging of Proposed Consent Decree Under the Comprehensive Environmental Response...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-29

    ... agree to reimburse the United States and the State for natural resource damage assessment costs ($31,060... Section, Environment and Natural Resources Division. [FR Doc. 2013-01761 Filed 1-28-13; 8:45 am] BILLING... Environmental Response, Compensation, and Liability Act On January 22, 2013, the Department of Justice lodged a...

  3. 76 FR 5830 - FBI Records Management Division; National Name Check Program Section; New User Fees Schedule

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-02

    ... study employed the same Activity Based Cost (ABC) accounting method detailed in the Final Rule establishing the process for setting fees (75 FR 24796 (May 6, 2010)). The ABC methodology is consistent with widely accepted accounting principles and complies with the provisions of 31 U.S.C. 9701 and other...

  4. Funding Request to Organize DPF2002 at the College of William and Mary, May 24-28, 2002

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Marc Sher

    We request $35,000 from the Department of Energy to help defray the cost of organizing the 2002 Meeting of the Division of Particles and Fields (DPF2002) of the American Physical Society on May 24-28, 2002 at The College of William and Mary, Williamsburg, Virginia.

  5. North Carolina Community College System Economic & Workforce Development Annual Report, 1999-2000.

    ERIC Educational Resources Information Center

    Lancaster, H. Martin

    During the 1999-2000 program year, the Division of Economic and Workforce Development attempted to further the North Carolina Community College System's (NCCCS) tradition of excellence by modeling key strategies of the business sector. These strategies included: (1) Economies of scale, a term that refers to unit cost decreasing as number of units…

  6. 76 FR 54486 - Buy American Exception Under the American Recovery and Reinvestment Act of 2009

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-01

    ... decision to approve the Buy American waiver requested by the SDBOC to purchase foreign ductile iron flanges... the Buy American waiver requested by the Sunnyside Division Board of Control (SDBOC) to purchase... will increase the cost of the overall project contract by more than 25 percent. The waiver process is...

  7. Job Dissatisfaction and Turnover among Two Year College Department/Division Chairpersons.

    ERIC Educational Resources Information Center

    Murray, John; Murray, Judy

    Research shows that turnover in managerial positions can cost an organization from 5 to 25 times an employee's monthly salary. Although some turnover is inevitable, many times it is caused by employee dissatisfaction with the job or its conditions, and this dissatisfaction is often directly attributable to stress resulting from role conflict or…

  8. Division or department: a microeconomic analysis.

    PubMed

    Mar, Philip L; Yu, Robert A; Yu, Jack C

    2011-06-01

    In this article, the authors present a microeconomic analysis of the effects of the administrative status on plastic surgery units within academic medical centers, comparing the departmental versus subdepartmental status. The objectives are to introduce decision-making tools of microeconomics and use them to explore the potential effects of administrative status on academic plastic surgery services. Real financial data over a decade were used to construct total cost (TC), average total cost (ATC), and total revenue (TR) curves. From these, the authors derive the efficiency scale and express the fiscal performance by examining profitability, and the commonly used ATC curve. Mathematical modeling is then used to examine the effects of departmental versus subdepartmental status, assuming that (1) a plastic surgery unit exists in a competitive market; and (2) TR > TC for the plastic surgery unit to self-sustain in the long term. The variables considered are total clinical production (Q), gross collection rates (GCR), personnel cost, and departmental tax. The sustainability (Q against GCR) is a hyperbolic curve with Q × GCR = TC at break-even. The TC/TR = f(TR) curve resembles the ATC curve. Sectional versus departmental status for a plastic surgery service in an academic medical center depends greatly on the shape of their TC/TR = f(TR) curve. With most competing clinical units within the same academic medical center having departmental status, and most competing private surgeons having no institutional "taxes," the essential requirement for academic medical center plastic surgery services is to ensure that their TC/TR = f(TR) curve is comparable to that of their competitors.

  9. Distributed information system (water fact sheet)

    USGS Publications Warehouse

    Harbaugh, A.W.

    1986-01-01

    During 1982-85, the Water Resources Division (WRD) of the U.S. Geological Survey (USGS) installed over 70 large minicomputers in offices across the country to support its mission in the science of hydrology. These computers are connected by a communications network that allows information to be shared among computers in each office. The computers and network together are known as the Distributed Information System (DIS). The computers are accessed through the use of more than 1500 terminals and minicomputers. The WRD has three fundamentally different needs for computing: data management; hydrologic analysis; and administration. Data management accounts for 50% of the computational workload of WRD because hydrologic data are collected in all 50 states, Puerto Rico, and the Pacific trust territories. Hydrologic analysis consists of 40% of the computational workload of WRD. Cost accounting, payroll, personnel records, and planning for WRD programs occupies an estimated 10% of the computer workload. The DIS communications network is shown on a map. (Lantz-PTT)

  10. An analysis of the job of strength and conditioning coach for football at the Division II level.

    PubMed

    Massey, C Dwayne; Schwind, Justin J; Andrews, Donnie C; Maneval, Mark W

    2009-12-01

    The purpose of this investigation was to describe the working environment of the heretofore unexamined Division II football strength and conditioning coach (SCC). Data were collected on demographic characteristics, job satisfaction, major job duties and responsibilities, work environment, and professional and personal relationships. A total of 63 questionnaires were returned by the potential 155 institutions identified at the Division II level. Percentages were used in the reporting of data. The results indicate that this group is relatively young (34.1), new to the profession, have low job stability, a low rate of professional certification, make a salary less than their Division I-A counterparts, and assume more duties and responsibilities than their Division I-A colleagues. Despite these apparent drawbacks, by and large, these SCC appeared content with their career choice and circumstances.

  11. Data Integration Framework Data Management Plan Remote Sensing Dataset

    DTIC Science & Technology

    2016-07-01

    performed by the Coastal Observations and Analysis Branch (CEERD-HFA) of the Flood and Storm Protection Division (CEERD-HF), U.S. Army Engineer Research... Protection Division, Coastal Observations and Analysis Branch CESAM U.S. Army Corps of Engineers, Mobile District CESAM-OP-J U.S. Army Corps of Engineers...ER D C/ CH L SR -1 6- 2 Coastal Ocean Data Systems Program Data Integration Framework Data Management Plan Remote Sensing Dataset Co

  12. Role Of Social Networks In Resilience Of Naval Recruits: A Quantitative Analysis

    DTIC Science & Technology

    2016-06-01

    comprises 1,297 total surveys from a total of eight divisions of recruits at two different time periods. Quantitative analyses using surveys and network... surveys from a total of eight divisions of recruits at two different time periods. Quantitative analyses using surveys and network data examine the effects...NETWORKS IN RESILIENCE OF NAVAL RECRUITS: A QUANTITATIVE ANALYSIS by Andrea M. Watling June 2016 Thesis Advisor: Edward H. Powley Co

  13. Biomechanical and Performance Differences Between Female Soccer Athletes in National Collegiate Athletic Association Divisions I and III

    PubMed Central

    Smith, Rose; Ford, Kevin R; Myer, Gregory D; Holleran, Adam; Treadway, Erin; Hewett, Timothy E

    2007-01-01

    Context: The recent increase in women's varsity soccer participation has been accompanied by a lower extremity injury rate that is 2 to 6 times that of their male counterparts. Objective: To define the differences between lower extremity biomechanics (knee abduction and knee flexion measures) and performance (maximal vertical jump height) between National Collegiate Athletic Association Division I and III female soccer athletes during a drop vertical jump. Design: Mixed 2 × 2 design. Setting: Research laboratory. Patients or Other Participants: Thirty-four female collegiate soccer players (Division I: n = 19; Division III: n = 15) participated in the study. The groups were similar in height and mass. Intervention(s): Each subject performed a maximal vertical jump, followed by 3 drop vertical jumps. Main Outcome Measure(s): Kinematics (knee abduction and flexion angles) and kinetics (knee abduction and flexion moments) were measured with a motion analysis system and 2 force platforms during the drop vertical jumps. Results: Knee abduction angular range of motion and knee abduction external moments were not different between groups (P > .05). However, Division I athletes demonstrated decreased knee flexion range of motion (P = .038) and greater peak external knee flexion moment (P = .009) compared with Division III athletes. Division I athletes demonstrated increased vertical jump height compared with Division III (P = .008). Conclusions: Division I athletes demonstrated different sagittal-plane mechanics than Division III athletes, which may facilitate improved performance. The similarities in anterior cruciate ligament injury risk factors (knee abduction torques and angles) may correlate with the consistent incidence of anterior cruciate ligament injury across divisions. PMID:18174935

  14. [Threshold value for reimbursement of costs of new drugs: cost-effectiveness research and modelling are essential links].

    PubMed

    Frederix, Geert W J; Hövels, Anke M; Severens, Johan L; Raaijmakers, Jan A M; Schellens, Jan H M

    2015-01-01

    There is increasing discussion in the Netherlands about the introduction of a threshold value for the costs per extra year of life when reimbursing costs of new drugs. The Medicines Committee ('Commissie Geneesmiddelen'), a division of the Netherlands National Healthcare Institute ('Zorginstituut Nederland'), advises on reimbursement of costs of new drugs. This advice is based upon the determination of therapeutic value of the drug and the results of economic evaluations. Mathematical models that predict future costs and effectiveness are often used in economic evaluations; these models can vary greatly in transparency and quality due to author assumptions. Standardisation of cost-effectiveness models is one solution to overcome the unwanted variation in quality. Discussions about the introduction of a threshold value can only be meaningful if all involved are adequately informed, and by high quality in cost-effectiveness research and, particularly, economic evaluations. Collaboration and discussion between medical specialists, patients or patient organisations, health economists and policy makers, both in development of methods and in standardisation, are essential to improve the quality of decision making.

  15. The Phragmoplast-Orienting Kinesin-12 Class Proteins Translate the Positional Information of the Preprophase Band to Establish the Cortical Division Zone in Arabidopsis thaliana[C][W

    PubMed Central

    Lipka, Elisabeth; Gadeyne, Astrid; Stöckle, Dorothee; Zimmermann, Steffi; De Jaeger, Geert; Ehrhardt, David W.; Kirik, Viktor; Van Damme, Daniel; Müller, Sabine

    2014-01-01

    The preprophase band (PPB) is a faithful but transient predictor of the division plane in somatic cell divisions. Throughout mitosis the PPBs positional information is preserved by factors that continuously mark the division plane at the cell cortex, the cortical division zone, by their distinct spatio-temporal localization patterns. However, the mechanism maintaining these identity factors at the plasma membrane after PPB disassembly remains obscure. The pair of kinesin-12 class proteins PHRAGMOPLAST ORIENTING KINESIN1 (POK1) and POK2 are key players in division plane maintenance. Here, we show that POK1 is continuously present at the cell cortex, providing a spatial reference for the site formerly occupied by the PPB. Fluorescence recovery after photobleaching analysis combined with microtubule destabilization revealed dynamic microtubule-dependent recruitment of POK1 to the PPB during prophase, while POK1 retention at the cortical division zone in the absence of cortical microtubules appeared static. POK function is strictly required to maintain the division plane identity factor TANGLED (TAN) after PPB disassembly, although POK1 and TAN recruitment to the PPB occur independently during prophase. Together, our data suggest that POKs represent fundamental early anchoring components of the cortical division zone, translating and preserving the positional information of the PPB by maintaining downstream identity markers. PMID:24972597

  16. 78 FR 68375 - Removal of Procedures for Closeout of Grants and Cooperative Agreements

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-14

    ..., Contract Management Division, Washington, DC 20546. Comments may also be submitted by email to: leigh... Procurement, Contract Management Division (Room 2P77); Telephone: (202) 358-0592; Email: [email protected] encouraged to perform retrospective analysis, reviewing existing regulation for outmoded, ineffective...

  17. 77 FR 32712 - Technical Report: Evaluation of the Enhancing Vehicle-to-Vehicle Crash Compatibility Agreement...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-01

    ... information provided. FOR FURTHER INFORMATION CONTACT: Nathan K. Greenwell, Mathematical Statistician, Evaluation Division, NVS-431, National Center for Statistics and Analysis, National Highway Traffic Safety... you to send a copy to Nathan K. Greenwell, Mathematical Statistician, Evaluation Division, NVS-431...

  18. 76 FR 27563 - Margin and Capital Requirements for Covered Swap Entities

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-11

    .... Board: Sean D. Campbell, Deputy Associate Director, Division of Research and Statistics, (202) 452-3761, Michael Gibson, Senior Associate Director, Division of Research and Statistics, (202) 452- 2495, or Jeremy..., DC 20429. FHFA: Robert Collender, Principal Policy Analyst, Office of Policy Analysis and Research...

  19. Leading by Example? ALA Division Publications, Open Access, and Sustainability

    ERIC Educational Resources Information Center

    Hall, Nathan; Arnold-Garza, Sara; Gong, Regina; Shorish, Yasmeen

    2016-01-01

    This investigation explores scholarly communication business models in American Library Association (ALA) division peer-reviewed academic journals. Previous studies reveal the numerous issues organizations and publishers face in the academic publishing environment. Through an analysis of documented procedures, policies, and finances of five ALA…

  20. Novel cost controlled materials and processing for primary structures

    NASA Technical Reports Server (NTRS)

    Dastin, S. J.

    1993-01-01

    Textile laminates, developed a number of years ago, have recently been shown to be applicable to primary aircraft structures for both small and large components. Such structures have the potential to reduce acquisition costs but require advanced automated processing to keep costs controlled while verifying product reliability and assuring structural integrity, durability and affordable life-cycle costs. Recently, resin systems and graphite-reinforced woven shapes have been developed that have the potential for improved RTM processes for aircraft structures. Ciba-Geigy, Brochier Division has registered an RTM prepreg reinforcement called 'Injectex' that has shown effectivity for aircraft components. Other novel approaches discussed are thermotropic resins producing components by injection molding and ceramic polymers for long-duration hot structures. The potential of such materials and processing will be reviewed along with initial information/data available to date.

  1. Small worlds in space: Synchronization, spatial and relational modularity

    NASA Astrophysics Data System (ADS)

    Brede, M.

    2010-06-01

    In this letter we investigate networks that have been optimized to realize a trade-off between enhanced synchronization and cost of wire to connect the nodes in space. Analyzing the evolved arrangement of nodes in space and their corresponding network topology, a class of small-world networks characterized by spatial and network modularity is found. More precisely, for low cost of wire optimal configurations are characterized by a division of nodes into two spatial groups with maximum distance from each other, whereas network modularity is low. For high cost of wire, the nodes organize into several distinct groups in space that correspond to network modules connected on a ring. In between, spatially and relationally modular small-world networks are found.

  2. Petroleum marketing monthly with data for May 1997

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    1997-08-01

    The Petroleum Marketing Monthly (PMM) provides information and statistical data on a variety of crude oils and refined petroleum products. The publication presents statistics on crude oil costs and refined petroleum products sales for use by industry, government, private sector analysts, educational institutions, and consumers. Data on crude oil include the domestic first purchase price, the f.o.b. and landed cost of crude oil, and the refiners` acquisition cost of crude oil. Refined petroleum product sales data include motor gasoline, distillates, residuals, aviation fuels, kerosene, and propane. The Petroleum Marketing Division, Office of Oil and Gas, Energy Information Administration ensures themore » accuracy, quality, and confidentiality of the published data in the Petroleum Marketing Monthly.« less

  3. A Versatile Multichannel Digital Signal Processing Module for Microcalorimeter Arrays

    NASA Astrophysics Data System (ADS)

    Tan, H.; Collins, J. W.; Walby, M.; Hennig, W.; Warburton, W. K.; Grudberg, P.

    2012-06-01

    Different techniques have been developed for reading out microcalorimeter sensor arrays: individual outputs for small arrays, and time-division or frequency-division or code-division multiplexing for large arrays. Typically, raw waveform data are first read out from the arrays using one of these techniques and then stored on computer hard drives for offline optimum filtering, leading not only to requirements for large storage space but also limitations on achievable count rate. Thus, a read-out module that is capable of processing microcalorimeter signals in real time will be highly desirable. We have developed multichannel digital signal processing electronics that are capable of on-board, real time processing of microcalorimeter sensor signals from multiplexed or individual pixel arrays. It is a 3U PXI module consisting of a standardized core processor board and a set of daughter boards. Each daughter board is designed to interface a specific type of microcalorimeter array to the core processor. The combination of the standardized core plus this set of easily designed and modified daughter boards results in a versatile data acquisition module that not only can easily expand to future detector systems, but is also low cost. In this paper, we first present the core processor/daughter board architecture, and then report the performance of an 8-channel daughter board, which digitizes individual pixel outputs at 1 MSPS with 16-bit precision. We will also introduce a time-division multiplexing type daughter board, which takes in time-division multiplexing signals through fiber-optic cables and then processes the digital signals to generate energy spectra in real time.

  4. Control of cell division and the spatial localization of assembled gene products in Caulobacter crescentus

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Nathan, P.D.

    Experiments are described that examine the role of penicillin-binding proteins (PBPs) in the regulation of cell division in Caulobacter crescentus; and the spatial localization of methyl-accepting chemotaxis proteins (MCPs) in C. crescentus swarmer and predivisional cells. In the analysis of PBP function, in vivo and in vitro assays are used to directly label C. crescentus PBPs with (/sup 3/H) penicillin G in wild type strain CB15, in a series of conditional cell division mutants and in new temperature sensitive cephalosporin C resistant mutants PC8002 and PC8003. 14 PBPs are characterized and a high molecular weight PBP (PBP 1B) that ismore » required for cell division is identified. PBP 1B competes for ..beta..-lactams that induce filament formation and may be a high affinity binding protein. A second high molecular weight PBP (PBP 1C) is also associated with defective cell division. The examination of PBP patterns in synchronous swarmer cells reveals that the in vivo activity of PBP 1B and PBP 1C increases at the time that the cell division pathway is initiated. None of the PBPs, however, appear to be differentially localized in the C. crescentus cell. In the analysis of MCP localization, in vivo and in vitro assays are used to directly label C. crescentus MCPs with methyl-/sup 3/H. MCPs are examined in flagellated and non-flagellated vesicles prepared from cells by immunoaffinity chromatography.« less

  5. A New Random Walk for Replica Detection in WSNs.

    PubMed

    Aalsalem, Mohammed Y; Khan, Wazir Zada; Saad, N M; Hossain, Md Shohrab; Atiquzzaman, Mohammed; Khan, Muhammad Khurram

    2016-01-01

    Wireless Sensor Networks (WSNs) are vulnerable to Node Replication attacks or Clone attacks. Among all the existing clone detection protocols in WSNs, RAWL shows the most promising results by employing Simple Random Walk (SRW). More recently, RAND outperforms RAWL by incorporating Network Division with SRW. Both RAND and RAWL have used SRW for random selection of witness nodes which is problematic because of frequently revisiting the previously passed nodes that leads to longer delays, high expenditures of energy with lower probability that witness nodes intersect. To circumvent this problem, we propose to employ a new kind of constrained random walk, namely Single Stage Memory Random Walk and present a distributed technique called SSRWND (Single Stage Memory Random Walk with Network Division). In SSRWND, single stage memory random walk is combined with network division aiming to decrease the communication and memory costs while keeping the detection probability higher. Through intensive simulations it is verified that SSRWND guarantees higher witness node security with moderate communication and memory overheads. SSRWND is expedient for security oriented application fields of WSNs like military and medical.

  6. A New Random Walk for Replica Detection in WSNs

    PubMed Central

    Aalsalem, Mohammed Y.; Saad, N. M.; Hossain, Md. Shohrab; Atiquzzaman, Mohammed; Khan, Muhammad Khurram

    2016-01-01

    Wireless Sensor Networks (WSNs) are vulnerable to Node Replication attacks or Clone attacks. Among all the existing clone detection protocols in WSNs, RAWL shows the most promising results by employing Simple Random Walk (SRW). More recently, RAND outperforms RAWL by incorporating Network Division with SRW. Both RAND and RAWL have used SRW for random selection of witness nodes which is problematic because of frequently revisiting the previously passed nodes that leads to longer delays, high expenditures of energy with lower probability that witness nodes intersect. To circumvent this problem, we propose to employ a new kind of constrained random walk, namely Single Stage Memory Random Walk and present a distributed technique called SSRWND (Single Stage Memory Random Walk with Network Division). In SSRWND, single stage memory random walk is combined with network division aiming to decrease the communication and memory costs while keeping the detection probability higher. Through intensive simulations it is verified that SSRWND guarantees higher witness node security with moderate communication and memory overheads. SSRWND is expedient for security oriented application fields of WSNs like military and medical. PMID:27409082

  7. Publications - GMC 274 | Alaska Division of Geological & Geophysical

    Science.gov Websites

    DGGS GMC 274 Publication Details Title: Total organic carbon analysis with leaching factor from for more information. Bibliographic Reference Brown and Ruth Laboratories, Inc., 1996, Total organic Information gmc274.pdf (109.0 K) Keywords Organic Carbon Top of Page Department of Natural Resources, Division

  8. The Construction of Academic Time: Sub/Contracting Academic Labour in Research.

    ERIC Educational Resources Information Center

    Hey, Valerie

    2001-01-01

    Offers a poststructuralist analysis of the UK higher education sector's academic division of labor, exploring some new contradictions from a contract researcher's standpoint. Raises political, social, and methodological questions about these divisions by exploring their class and gender dimensions. Too many academics remain silent about adverse…

  9. Theatre for Development: An Overview.

    ERIC Educational Resources Information Center

    Nogueira, Marcia Pompeo

    2002-01-01

    Discusses the term Theatre for Development (TFD) by addressing the theatre practice developed by a group of women in Mundemba Sub-Division, Cameroon, which was presented in Anne Tanyi-Tang's article "Theatre for Change: An Analysis of Two Performances by Women in Mundemba Sub-Division" in an earlier issue of this journal. Considers…

  10. Analysis of the Effects of Phase Noise and Frequency Offset in Orthogonal Frequency Division Multiplexing (OFDM) Systems

    DTIC Science & Technology

    2004-03-01

    Data Communication , http://www.iec.org/, last accessed December 2003. 13. Klaus Witrisal, “Orthogonal Frequency Division Multiplexing (OFDM) for...http://ieeexplore.ieee.org, last accessed 26 February 2003. 12. The International Engineering Consortium, Web Forum Tutorials, OFDM for Mobile

  11. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    The primary purpose of this report is to provide an archival record of the activities of the Engineering Physics and Mathematics Division during the period September 1, 1989 through March 31, 1991. Earlier reports in this series are identified on the previous pages, along with the progress reports describing ORNL's research on the mathematical sciences prior to 1984 when those activities moved into the division. As in previous reports, our research is described through abstracts of journal articles, technical reports, and presentations. Summary lists of publications and presentations, staff additions and departures, scientific and professional activities of division staff, andmore » technical conferences organized and sponsored by the division are included as appendices. The report is organized following the division of our research among four sections and information centers. These research areas are: Mathematical Sciences; Nuclear Data Measurement and Evaluations; Intelligent Systems; Nuclear Analysis and Shielding; and Engineering Physics Information Center.« less

  12. Identification of putative Z-ring-associated proteins, involved in cell division in human pathogenic bacteria Helicobacter pylori.

    PubMed

    Kamran, Mohammad; Sinha, Swati; Dubey, Priyanka; Lynn, Andrew M; Dhar, Suman K

    2016-07-01

    Cell division in bacteria is initiated by FtsZ, which forms a Z ring at the middle of the cell, between the nucleoids. The Z ring is stabilized by Z ring-associated proteins (Zaps), which crosslink the FtsZ filaments and provide strength. The deletion of Zaps leads to the elongation phenotype with an abnormal Z ring. The components of cell division in Helicobacter pylori are similar to other gram negative bacteria except for the absence of few components including Zaps. Here, we used HHsearch to identify homologs of the missing cell division proteins and got potential hits for ZapA and ZapB, as well as for few other cell division proteins. We further validated the function of the putative ZapA homolog by genetic complementation, immuno-colocalization and biochemical analysis. © 2016 Federation of European Biochemical Societies.

  13. A genetic screen for temperature-sensitive cell-division mutants of Caenorhabditis elegans.

    PubMed Central

    O'Connell, K F; Leys, C M; White, J G

    1998-01-01

    A novel screen to isolate conditional cell-division mutants in Caenorhabditis elegans has been developed. The screen is based on the phenotypes associated with existing cell-division mutations: some disrupt postembryonic divisions and affect formation of the gonad and ventral nerve cord-resulting in sterile, uncoordinated animals-while others affect embryonic divisions and result in lethality. We obtained 19 conditional mutants that displayed these phenotypes when shifted to the restrictive temperature at the appropriate developmental stage. Eighteen of these mutations have been mapped; 17 proved to be single alleles of newly identified genes, while 1 proved to be an allele of a previously identified gene. Genetic tests on the embryonic lethal phenotypes indicated that for 13 genes, embryogenesis required maternal expression, while for 6, zygotic expression could suffice. In all cases, maternal expression of wild-type activity was found to be largely sufficient for embryogenesis. Cytological analysis revealed that 10 mutants possessed embryonic cell-division defects, including failure to properly segregate DNA, failure to assemble a mitotic spindle, late cytokinesis defects, prolonged cell cycles, and improperly oriented mitotic spindles. We conclude that this approach can be used to identify mutations that affect various aspects of the cell-division cycle. PMID:9649522

  14. Fixed-point image orthorectification algorithms for reduced computational cost

    NASA Astrophysics Data System (ADS)

    French, Joseph Clinton

    Imaging systems have been applied to many new applications in recent years. With the advent of low-cost, low-power focal planes and more powerful, lower cost computers, remote sensing applications have become more wide spread. Many of these applications require some form of geolocation, especially when relative distances are desired. However, when greater global positional accuracy is needed, orthorectification becomes necessary. Orthorectification is the process of projecting an image onto a Digital Elevation Map (DEM), which removes terrain distortions and corrects the perspective distortion by changing the viewing angle to be perpendicular to the projection plane. Orthorectification is used in disaster tracking, landscape management, wildlife monitoring and many other applications. However, orthorectification is a computationally expensive process due to floating point operations and divisions in the algorithm. To reduce the computational cost of on-board processing, two novel algorithm modifications are proposed. One modification is projection utilizing fixed-point arithmetic. Fixed point arithmetic removes the floating point operations and reduces the processing time by operating only on integers. The second modification is replacement of the division inherent in projection with a multiplication of the inverse. The inverse must operate iteratively. Therefore, the inverse is replaced with a linear approximation. As a result of these modifications, the processing time of projection is reduced by a factor of 1.3x with an average pixel position error of 0.2% of a pixel size for 128-bit integer processing and over 4x with an average pixel position error of less than 13% of a pixel size for a 64-bit integer processing. A secondary inverse function approximation is also developed that replaces the linear approximation with a quadratic. The quadratic approximation produces a more accurate approximation of the inverse, allowing for an integer multiplication calculation to be used in place of the traditional floating point division. This method increases the throughput of the orthorectification operation by 38% when compared to floating point processing. Additionally, this method improves the accuracy of the existing integer-based orthorectification algorithms in terms of average pixel distance, increasing the accuracy of the algorithm by more than 5x. The quadratic function reduces the pixel position error to 2% and is still 2.8x faster than the 128-bit floating point algorithm.

  15. Somatotype, Level of Competition, and Performance in Attack in Elite Male Volleyball

    PubMed Central

    Giannopoulos, Nikiforos; Vagenas, George; Noutsos, Konstantinos; Barzouka, Karolina; Bergeles, Nikolaos

    2017-01-01

    Abstract This study investigated the relationship between somatotype, level of competition, and performance in attack in elite level male volleyball players. The objective was to test for the potential covariation of competition level (Division A1 vs. A2) and playing position (hitters vs. centers vs. opposites) considering performance in attack. Anthropometric, body composition and somatotype variables were measured according to the Heath-Carter method. The attack actions of 144 players from 48 volleyball matches were analyzed and their performance was rated using a 5-point numerical scale. Results showed that players of Division A1 were taller, heavier, more muscular, and less endomorphic compared to those of Division A2. MANOVA and follow-up discriminant function analysis revealed somatotype differences among playing positions with centers and opposites being endomorph-ectomorph and hitters being central. Centers performed constantly better than hitters and opposites regardless of the division and somatotype. Multiple linear regression analysis showed that variables defining ectomorph and endomorph players, centers, and players of Division A1 significantly determined the relative performance superiority and were able to explain the variation in performance by almost 25%. These results could be taken into account by coaches when assigning players to particular playing positions or when designing individualized position-specific training programs. PMID:28828084

  16. Somatotype, Level of Competition, and Performance in Attack in Elite Male Volleyball.

    PubMed

    Giannopoulos, Nikiforos; Vagenas, George; Noutsos, Konstantinos; Barzouka, Karolina; Bergeles, Nikolaos

    2017-09-01

    This study investigated the relationship between somatotype, level of competition, and performance in attack in elite level male volleyball players. The objective was to test for the potential covariation of competition level (Division A1 vs. A2) and playing position (hitters vs. centers vs. opposites) considering performance in attack. Anthropometric, body composition and somatotype variables were measured according to the Heath-Carter method. The attack actions of 144 players from 48 volleyball matches were analyzed and their performance was rated using a 5-point numerical scale. Results showed that players of Division A1 were taller, heavier, more muscular, and less endomorphic compared to those of Division A2. MANOVA and follow-up discriminant function analysis revealed somatotype differences among playing positions with centers and opposites being endomorph-ectomorph and hitters being central. Centers performed constantly better than hitters and opposites regardless of the division and somatotype. Multiple linear regression analysis showed that variables defining ectomorph and endomorph players, centers, and players of Division A1 significantly determined the relative performance superiority and were able to explain the variation in performance by almost 25%. These results could be taken into account by coaches when assigning players to particular playing positions or when designing individualized position-specific training programs.

  17. Identification of a high-virulence clone of type III Streptococcus agalactiae (group B Streptococcus) causing invasive neonatal disease.

    PubMed

    Musser, J M; Mattingly, S J; Quentin, R; Goudeau, A; Selander, R K

    1989-06-01

    Chromosomal genotypes of 128 isolates of six serotypes (Ia, Ib, Ic, II, Ic/II, and III) of Streptococcus agalactiae (group B Streptococcus) recovered predominantly from human infants in the United States were characterized by an analysis of electrophoretically demonstrable allelic profiles at 11 metabolic enzyme loci. Nineteen distinctive electrophoretic types (ETs), representing multilocus clonal genotypes, were identified. Mean genetic diversity per locus among ETs of isolates of the same serotype was, on average, nearly equal to that in all 19 ETs. Cluster analysis of the ETs revealed two primary phylogenetic divisions at a genetic distance of 0.65. A single clone (ET 1) represented by 40 isolates expressing type III antigen formed division I. Division II was composed of 18 ETs in three major lineages diverging from one another at distances greater than 0.35 and included strains of all six antigenic classes. The type III organisms in division I produce more extracellular neuraminidase and apparently are more virulent than the type III strains in division II, which are related to strains of other serotypes that cause disease much less frequently. The existence of this unusually virulent clone accounts, in major part, for the high morbidity and mortality associated with infection by type III organisms.

  18. Metabolic Context of the Competence-Induced Checkpoint for Cell Replication in Streptococcus suis.

    PubMed

    Zaccaria, Edoardo; Wells, Jerry M; van Baarlen, Peter

    2016-01-01

    Natural genetic transformation is a transient, rapidly progressing energy-consuming process characterized by expression of the transformasome and competence-associated regulatory genes. This transient state is tightly controlled to avoid potentially adverse effects of genetic recombination on genome integrity during cell division. We investigated the global response of Streptococcus suis to exposure to the SigX competence-inducing peptide (XIP), and thus to the activation of the competence machinery, using time series analysis together with PCA analysis, gene clustering followed by heatmap visualisation, and GO enrichment analysis. We explored the possible regulatory link between metabolism and competence, and predicted the physiological adaptation of S. suis during competence induction, progression and exit using transcriptome analysis. We showed that competence development is associated with a suppression of basal metabolism, which may have consequences for the microbe's resilience to fluctuations in the environment, as competence is costly in terms of use of energy and protein translation. Furthermore our data suggest that several basal metabolic pathways are incompatible with activation of competence in S. suis. This study also showed that targeting specific pathways during the development of competence, might render S. suis more vulnerable toward novel antibiotic therapies.

  19. Metabolic Context of the Competence-Induced Checkpoint for Cell Replication in Streptococcus suis

    PubMed Central

    Zaccaria, Edoardo; Wells, Jerry M.

    2016-01-01

    Natural genetic transformation is a transient, rapidly progressing energy-consuming process characterized by expression of the transformasome and competence-associated regulatory genes. This transient state is tightly controlled to avoid potentially adverse effects of genetic recombination on genome integrity during cell division. We investigated the global response of Streptococcus suis to exposure to the SigX competence-inducing peptide (XIP), and thus to the activation of the competence machinery, using time series analysis together with PCA analysis, gene clustering followed by heatmap visualisation, and GO enrichment analysis. We explored the possible regulatory link between metabolism and competence, and predicted the physiological adaptation of S. suis during competence induction, progression and exit using transcriptome analysis. We showed that competence development is associated with a suppression of basal metabolism, which may have consequences for the microbe's resilience to fluctuations in the environment, as competence is costly in terms of use of energy and protein translation. Furthermore our data suggest that several basal metabolic pathways are incompatible with activation of competence in S. suis. This study also showed that targeting specific pathways during the development of competence, might render S. suis more vulnerable toward novel antibiotic therapies. PMID:27149631

  20. 26 CFR 1.1041-1T - Treatment of transfer of property between spouses or incident to divorce (temporary).

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... whether the transfer is of property separately owned by the transferor or is a division (equal or unequal... includes a modification or amendment to such decree or instrument. Any transfer not pursuant to a divorce... the transferred property equal to the transferee's cost (the fair market value). This carryover basis...

  1. Learning about Heredity and Embryology. Superific Science Book II. A Good Apple Science Activity Book for Grades 5-8+.

    ERIC Educational Resources Information Center

    Conway, Lorraine

    Designed to provide teachers with low cost laboratory exercises, project ideas, and classroom activities for individuals and groups, this document focuses on the concepts of heredity and embryology. The materials address the topics of: (1) cell division; (2) the identification of the human embryo; (3) chromosomes; (4) DNA; (5) differences in the…

  2. JPRS Report, Near East and South Asia.

    DTIC Science & Technology

    1991-10-31

    the rise in the cost cussion on the conflict-resolution potential of the solu- of the nuclear station’s construction was among ... the world, has only two options for an agreed solution: Spain in the Middle Ages]," the lost Garden of Eden, an a vertical or a horizontal division...position willingness to wallow in reality and experience its dull- of

  3. SPECIAL PURPOSE IT DERAILED: UNINTENDED CONSEQUENCES OF UNIVERSAL IT LAWS AND POLICIES

    DTIC Science & Technology

    2017-10-26

    Information Services Division ........................ 3 Figure 2: iNET Instrumentation Telemetry Ground Station...consolidate local Information Technology (IT) networks into an enterprise architecture to reduce costs and to increase security. Leadership coined this...IT network was established to link Air Force and contractor sites to seamlessly share program information . So when Air Force IT leadership tried to

  4. Overview of State Policies on Lower-Division General Education Core in the WICHE States. Interstate Passport

    ERIC Educational Resources Information Center

    Western Interstate Commission for Higher Education, 2011

    2011-01-01

    The WICHE Interstate Passport Initiative, launched in October 2011, is a pilot project that addresses interstate student transfer. When students transfer from one postsecondary institution to another--both within and out of state--they may be required to repeat courses, which can add to the time and cost of completing their education. Although…

  5. A Look Inside the Juno Mission to Jupiter

    NASA Technical Reports Server (NTRS)

    Grammier, Richard S.

    2008-01-01

    Juno, the second mission within the New Frontiers Program, is a Jupiter polar orbiter mission designed to return high-priority science data that spans across multiple divisions within NASA's Science Mission Directorate. Juno's science objectives, coupled with the natural constraints of a cost-capped, PI-led mission and the harsh environment of Jupiter, have led to a very unique mission and spacecraft design.

  6. USMC ISR: Preparing for the A2AD Threat

    DTIC Science & Technology

    2014-06-13

    millimeter waves, high - power microwaves, lasers or electromagnetic pulses (Brimley 2013, 15). Replacing modern day munitions, directed- energy ...space and cyber capabilities” (JCS, 26). The precept further states the need to protect access to the electromagnetic spectrum. Given the high cost...is the “division of electronic warfare involving the use of electromagnetic , directed energy , or antiradiation weapons to attack personnel, facilities

  7. 10Gbps monolithic silicon FTTH transceiver without laser diode for a new PON configuration.

    PubMed

    Zhang, Jing; Liow, Tsung-Yang; Lo, Guo-Qiang; Kwong, Dim-Lee

    2010-03-01

    A new passive optical network (PON) configuration and a novel silicon photonic transceiver architecture for optical network unit (ONU) are proposed, eliminating the need for an internal laser source in ONU. The Si transceiver is fully monolithic, includes integrated wavelength division multiplexing (WDM) filters, modulators (MOD) and photo-detectors (PD), and demonstrates low-cost high volume manufacturability.

  8. Administrative and Leadership Innovation in the 21st Century: A Secondary School Sub-Sector Perspective in Kenya

    ERIC Educational Resources Information Center

    Kaume-Mwinzi, Regina K.

    2016-01-01

    Studies have indicated that in education, the traditional management paradigm maintains an inward focus with the aim of cutting costs, upholding rules and division of labour. However, the 21st century has ushered in a new revolution in education leadership structures which are less hierarchical, more flattened and more fluid organizations. The…

  9. Extended Follow-Up Frequently Asked Questions | Division of Cancer Prevention

    Cancer.gov

    1. What is the PLCO Central Data Coordinating Center?The PLCO Central Data Coordinating Center (CDCC) is an extension of the Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Trial. The extension will be coordinated by one site under the direction of the National Cancer Institute (NCI) rather than ten PLCO Screening Centers to reduce costs. Westat which has served

  10. Comparative and Cumulative Energetic Costs of Odontocete Responses to Anthropogenic Disturbance

    DTIC Science & Technology

    2015-09-30

    Responses to Anthropogenic Disturbance Dawn P. Noren & Marla M. Holt NOAA NMFS Northwest Fisheries Science Center 2725 Montlake Blvd. East...divisions/cbd/marine_mammal/marinemammal.cfm LONG-TERM GOALS Cetacean responses to marine anthropogenic activities include changes in acoustic... marine mammals. OBJECTIVES This investigation comprises five major objectives, executed over three years. The objectives are: (1) compare the

  11. Infrastructure Rationalization in the U.S. Naval Ship Industrial Base

    DTIC Science & Technology

    2008-11-01

    14 8. Historical FCFROIC and WACC for the Marine...on invested capital (FCFROIC).19 We compare the recent historical FCFROIC vs. the weighted average cost of capital ( WACC ) for the marine divisions of...than the WACC , the company is increasing shareholder wealth; if it is below the WACC , shareholder wealth is declining. In Figure 8, we see that

  12. An Open-source Meteorological Operational System and its Installation in Portuguese- speaking Countries

    NASA Astrophysics Data System (ADS)

    Almeida, W. G.; Ferreira, A. L.; Mendes, M. V.; Ribeiro, A.; Yoksas, T.

    2007-05-01

    CPTEC, a division of Brazil’s INPE, has been using several open-source software packages for a variety of tasks in its Data Division. Among these tools are ones traditionally used in research and educational communities such as GrADs (Grid Analysis and Display System from the Center for Ocean-Land-Atmosphere Studies (COLA)), the Local Data Manager (LDM) and GEMPAK (from Unidata), andl operational tools such the Automatic File Distributor (AFD) that are popular among National Meteorological Services. In addition, some tools developed locally at CPTEC are also being made available as open-source packages. One package is being used to manage the data from Automatic Weather Stations that INPE operates. This system uses only open- source tools such as MySQL database, PERL scripts and Java programs for web access, and Unidata’s Internet Data Distribution (IDD) system and AFD for data delivery. All of these packages are get bundled into a low-cost and easy to install and package called the Meteorological Data Operational System. Recently, in a cooperation with the SICLIMAD project, this system has been modified for use by Portuguese- speaking countries in Africa to manage data from many Automatic Weather Stations that are being installed in these countries under SICLIMAD sponsorship. In this presentation we describe the tools included-in and and architecture-of the Meteorological Data Operational System.

  13. Information seeking for making evidence-informed decisions: a social network analysis on the staff of a public health department in Canada

    PubMed Central

    2012-01-01

    Background Social network analysis is an approach to study the interactions and exchange of resources among people. It can help understanding the underlying structural and behavioral complexities that influence the process of capacity building towards evidence-informed decision making. A social network analysis was conducted to understand if and how the staff of a public health department in Ontario turn to peers to get help incorporating research evidence into practice. Methods The staff were invited to respond to an online questionnaire inquiring about information seeking behavior, identification of colleague expertise, and friendship status. Three networks were developed based on the 170 participants. Overall shape, key indices, the most central people and brokers, and their characteristics were identified. Results The network analysis showed a low density and localized information-seeking network. Inter-personal connections were mainly clustered by organizational divisions; and people tended to limit information-seeking connections to a handful of peers in their division. However, recognition of expertise and friendship networks showed more cross-divisional connections. Members of the office of the Medical Officer of Health were located at the heart of the department, bridging across divisions. A small group of professional consultants and middle managers were the most-central staff in the network, also connecting their divisions to the center of the information-seeking network. In each division, there were some locally central staff, mainly practitioners, who connected their neighboring peers; but they were not necessarily connected to other experts or managers. Conclusions The methods of social network analysis were useful in providing a systems approach to understand how knowledge might flow in an organization. The findings of this study can be used to identify early adopters of knowledge translation interventions, forming Communities of Practice, and potential internal knowledge brokers. PMID:22591757

  14. Multi-element fiber technology for space-division multiplexing applications.

    PubMed

    Jain, S; Rancaño, V J F; May-Smith, T C; Petropoulos, P; Sahu, J K; Richardson, D J

    2014-02-24

    A novel technological approach to space division multiplexing (SDM) based on the use of multiple individual fibers embedded in a common polymer coating material is presented, which is referred to as Multi-Element Fiber (MEF). The approach ensures ultralow crosstalk between spatial channels and allows for cost-effective ways of realizing multi-spatial channel amplification and signal multiplexing/demultiplexing. Both the fabrication and characterization of a passive 3-element MEF for data transmission, and an active 5-element erbium/ytterbium doped MEF for cladding-pumped optical amplification that uses one of the elements as an integrated pump delivery fiber is reported. Finally, both components were combined to emulate an optical fiber network comprising SDM transmission lines and amplifiers, and illustrate the compatibility of the approach with existing installed single-mode WDM fiber systems.

  15. A Novel Cost-effective OFDM WDM-PON Radio Over Fiber System Employing FBG to Generate Optical mm-wave

    NASA Astrophysics Data System (ADS)

    Nguyen, HoangViet

    2015-03-01

    We have investigated and demonstrated a novel scheme to generate 2.5 Gbit/s 64 QAM orthogonal frequency division multiplexing (OFDM) signals for Radio Over Fiber (ROF) systems. We employ Fiber Bragg Grating (FBG) because the repetitive frequency of the RF source and the bandwidth of the optical modulator are largely reduced and the architecture of the ROF system is simpler. Wavelength-Division-Multiplexed Passive Optical Network (WDM-PON) has been considered as a promising solution for future broadband access networks. Principle of WDM-PON access network compatible with OFDM-ROF systems is investigated. This novel scheme which has multiple double-frequency technique to generate mm-wave signal to carry OFDM signals is a practical scheme to be applied for future broadband access networks.

  16. The Optimal Allocation of Army Enlistment Incentives by MOS; Analyses of CY 86-87 Experience, Impacts of Nonmonetary Guidance Counselor Incentives, and PC Software

    DTIC Science & Technology

    1989-05-01

    0 ELECTE VARSHA P. RAO SEP11190 AND U DONNA ROBERTS MAY 1989 APPROVED FOR PUBLIC RELEASE; DISTRIBUTION UNLIMITED O Research & Studies Division U.S...DAKF 15-87-0-0144 Subcontract Sub-Hi 88-12, Do No. 88-007, with the Research and Studies Division, Program Analysis and Evaluation Directorate of...Toomepuu, Chief, Research and Studies Division, for their helpful counsel. ii TABLE OF CONTENTS PAGE DISCLAIMER ii ACKNOWLEDGMENTS ii LIST OF FIGURES v

  17. Spatial-temporal analysis of the of the risk of Rift Valley Fever in Kenya

    NASA Astrophysics Data System (ADS)

    Bett, B.; Omolo, A.; Hansen, F.; Notenbaert, A.; Kemp, S.

    2012-04-01

    Historical data on Rift Valley Fever (RVF) outbreaks in Kenya covering the period 1951 - 2010 were analyzed using a logistic regression model to identify factors associated with RVF occurrence. The analysis used a division, an administrative unit below a district, as the unit of analysis. The infection status of each division was defined on a monthly time scale and used as a dependent variable. Predictors investigated include: monthly precipitation (minimum, maximum and total), normalized difference vegetation index, altitude, agro-ecological zone, presence of game, livestock and human population densities, the number of times a division has had an outbreak before and time interval in months between successive outbreaks (used as a proxy for immunity). Both univariable and multivariable analyses were conducted. The models used incorporated an auto-regressive correlation matrix to account for clustering of observations in time, while dummy variables were fitted in the multivariable model to account for spatial relatedness/topology between divisions. This last procedure was followed because it is expected that the risk of RVF occurring in a given division increases when its immediate neighbor gets infected. Functional relationships between the continuous and the outcome variables were assessed to ensure that the linearity assumption was met. Deviance and leverage residuals were also generated from the final model and used for evaluating the goodness of fit of the model. Descriptive analyzes indicate that a total of 91 divisions in 42 districts (of the original 69 districts in place by 1999) reported RVF outbreaks at least once over the period. The mean interval between outbreaks was determined to be about 43 months. Factors that were positively associated with RVF occurrence include increased precipitation, high outbreak interval and the number of times a division has been infected or reported an outbreak. The model will be validated and used for developing an RVF forecasting system. This forecasting system can then be used with the existing regional RVF prediction tools such as EMPRES-i to downscale RVF risk predictions to country-specific scales and subsequently link them with decision support systems. The ultimate aim is to increase the capacity of the national institutions to formulate appropriate RVF mitigation measures.

  18. Beryllium and titanium cost-adjustment report

    NASA Astrophysics Data System (ADS)

    Owen, John; Ulph, Eric, Sr.

    1991-09-01

    This report summarizes cost adjustment factors for beryllium (Be, S200) and titanium (Ti, 6Al-4V) that were derived relative to aluminum (Al, 7075-T6). Aluminum is traditionally the material upon which many of the Cost Analysis Office, Missile Division cost estimating relationships (CERs) are based. The adjustment factors address both research and development and production (Q > 100) quantities. In addition, the factors derived include optical elements, normal structure, and structure with special requirements for minimal microcreep, such as sensor assembly parts and supporting components. Since booster cost per payload pound is an even larger factor in total missile launch costs than was initially presumed, the primary cost driver for all materials compared was the missiles' booster cost per payload pound for both R&D and production quantities. Al and Ti are 1.5 and 2.4 times more dense, respectively, than Be, and the cost to lift the heavier materials results in greater booster expense. In addition, Al and Ti must be 2.1 and 2.8, respectively, times the weight of a Be component to provide equivalent stiffness, based on the example component addressed in the report. These factors also increase booster costs. After review of the relative factors cited above, especially the lower costs for Be when stiffness and booster costs are taken into consideration, affordability becomes an important issue. When this study was initiated, both government and contractor engineers said that Be was the material to be used as a last resort because of its prohibitive cost and extreme toxicity. Although the initial price of Be may lead one to believe that any Be product would be extremely expensive, the total cost of Be used for space applications is actually competitive with or less costly than either Al or Ti. Also, the Be toxicity problem has turned out to be a non-issue for purchasers of finished Be components since no machining or grinding operations are required on the finished components. Several new costing techniques are developed which provide quantitative measures of the cost of material stiffness, costs related to payload weight, and costs associated with the relative temperature stability of different materials. In addition, use is made of the Design/Cost Trade Model developed by Applied Research, Inc., to determine the booster cost differential relative to changes in payload weight, and a mirror fabrication cost model, developed by OCA Applied Optics, was used for mirror costing. This report is a summary of an extensive study done by the U.S. Army Strategic Defense Command, Huntsville, Alabama.

  19. Energy and Environment Division annual report, 1978

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Camp, J.A.

    1978-01-01

    Research activities of this Division are reported under nine separate programs, namely: Energy Analysis; Solar Energy; Energy-Efficient Buildings; Chemical Process Research and Development; Environmental Research; Atmospheric Aerosol Research; Oil Shale Research; Instrumentation Development; and Combustion Research. A separate abstract was prepared for each of the nine programs, each of which contained several individual research summaries, with responsible researchers listed. All of the abstracts will appear in Energy Research Abstracts (ERA), and five will appear in Energy Abstracts for Policy Analysis (EAPA).

  20. Acoustic Source Bearing Estimation (ASBE) computer program development

    NASA Technical Reports Server (NTRS)

    Wiese, Michael R.

    1987-01-01

    A new bearing estimation algorithm (Acoustic Source Analysis Technique - ASAT) and an acoustic analysis computer program (Acoustic Source Bearing Estimation - ASBE) are described, which were developed by Computer Sciences Corporation for NASA Langley Research Center. The ASBE program is used by the Acoustics Division/Applied Acoustics Branch and the Instrument Research Division/Electro-Mechanical Instrumentation Branch to analyze acoustic data and estimate the azimuths from which the source signals radiated. Included are the input and output from a benchmark test case.

  1. Energy Division annual progress report for period ending September 30, 1983

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    This report covers work done during FY 1983 by the staff of the Energy Division and its subcontractors and by colleagues in other Oak Ridge National Laboratory divisions working on Energy Division projects. The work can be divided into four areas: (1) analysis and assessment, (2) models and data systems, (3) research to improve the efficiency of energy use and to improve electric power transmission and distribution, and (4) research utilization. Support came principally from the US Department of Energy (DOE), the US Nuclear Regulatory Commission, and the US Department of Defense, but also from a number of other agenciesmore » and organizations. Analysis and assessment included work on (a) environmental issues, including those deriving from the preparation of environmental impact statements; (b) energy and resource analysis; and (c) emergency preparedness. The models and data systems area involved research on evaluating and developing energy, environment, and engineering simulation models and on devising large data management systems, evaluating user data requirements, and compiling data bases. Research on improving the efficiency of energy use was focused primarily on the buildings and electricity sectors. A major effort on heat pump technology, which includes both heat-activated and electrically driven systems, continues. An important aspect of all the work was research utilization. Since the Energy Division is doing applied research, results are, by definition, intended to solve problems or answer questions of DOE and other sponsors. However, there are other users, and research utilization activities include technology transfer, commercialization efforts, outreach to state and regional organizations, and, of course, information dissemination.« less

  2. Military Family Housing in the United States

    DTIC Science & Technology

    1993-09-01

    Deborah Clay- Mendez of CBO’s National Security Division and Lisa Siegel of CBO’s Budget Analysis Division prepared the study under the general...Aging of DoD’s Housing Beaufort Marine Corps Air Station in South Caro - Stock hna. (Photo courtesy of the General Accounting Office) DoD uses the

  3. 77 FR 70482 - Notice of Establishment of a NASA Federal Advisory Committee; Applied Sciences Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-26

    ... Analysis Group (ASAG) as a task group under the auspices of the Earth Science Subcommittee of the NASA... and prioritizing the Earth Science Division's Applied Sciences Program activities and has served as a... recommendations to the Director, Earth Science Division, Science Mission Directorate, NASA Headquarters, on...

  4. Human Systems Integration at NASA Ames Research Center

    NASA Technical Reports Server (NTRS)

    McCandless, Jeffrey

    2017-01-01

    The Human Systems Integration Division focuses on the design and operations of complex aerospace systems through analysis, experimentation and modeling. With over a dozen labs and over 120 people, the division conducts research to improve safety, efficiency and mission success. Areas of investigation include applied vision research which will be discussed during this seminar.

  5. Publications - GMC 44 | Alaska Division of Geological & Geophysical Surveys

    Science.gov Websites

    and Facilities Staff Seismic and Well Data Data Reports Contact Us Frequently Asked Questions Ask a DGGS GMC 44 Publication Details Title: Carbon isotope analysis of carbonates from Ahtna #1 well, Copper of carbonates from Ahtna #1 well, Copper River Valley, Alaska: Alaska Division of Geological &

  6. MORPHOMETRIC ANALYSIS OF RAT HINDLIMB MALFORMATIONS DUE TO GESTATIONAL EXPOSURE TO 5-FU

    EPA Science Inventory

    SETZER1, R. W., M. D. WILLIAMS2, D. LITTON3, M.G. NAROTSKY4, 1Experimental Toxicology Division and 4Reproductive Toxicology Division, NHEERL, ORD, USEPA, Research Triangle Park, North Carolina; 2UNC School of Medicine, Chapel Hill, North Carolina; and 3Department of Aerospace E...

  7. 76 FR 41430 - Airworthiness Directives; Pratt & Whitney Division (PW) PW4000 Series Turbofan Engines

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-14

    ... removing certain part number (P/N) high-pressure turbine (HPT) stage 1 and HPT stage 2 airseals and HPT... and its high-pressure turbine (HPT). Pratt and Whitney's updated analysis indicated that the current...) Applicability This AD applies to the following Pratt & Whitney Division (PW) turbofan engines, with high...

  8. 76 FR 30942 - Notice of Availability of the Final Environmental Impact Statement for Improvements to the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-27

    ... Calexico, California. The Final EIS provides GSA and its stakeholders an analysis of the environmental... Sheehan, NEPA Project Manager, Portfolio Management Division, Capital Investment Branch (9P2PTC), U.S.../nepalibrary . Dated: May 19, 2011. Samuel R. Mazzola, Director, Portfolio Management Division, Pacific Rim...

  9. Web-Assisted Instruction in Upper Division Communication Studies Curriculum: A Theoretical and Quantitative Analysis

    ERIC Educational Resources Information Center

    Olaniran, Bolanle; Austin, Katherine A.

    2009-01-01

    Purpose: This paper aims to describe the incorporation of technologies into two upper division Communication Studies courses at Texas Tech University. Design/methodology/approach: The article discusses the methodological and pedagogical rationale used to select the appropriate technologies and to effectively incorporate them into the classroom. An…

  10. Logistics in hospitals: a case study of some Singapore hospitals.

    PubMed

    Pan, Zhi Xiong; Pokharel, Shaligram

    2007-01-01

    The purpose of this paper is to investigate logistics activities in Singapore hospitals. It defines various types of activities handled by a logistics division. Inventory management policy and the use of information and communication technologies (ICT) for logistics purposes are also discussed. The study identifies the nature of strategic alliances in Singapore's health care industry. This study was conducted by utilizing a framework for data collection, pre-testing the questionnaire and conducting interviews. Various relevant literature was reviewed to design the questionnaire. This study finds that logistics division carry out many related activities and some of them also provide engineering services. The hospitals make use of ICT. The hospitals are clustered under various groups to minimize the cost of operation, including the logistics related costs. However, hospitals do not see alliances with suppliers as a strategic option; rather they focus on outsourcing of logistics services. The findings also show that Singapore hospitals have a good stocking policy for both medical and non-medical items so that changes in patient mix can be easily handled. Singapore is continuously improving its health care industry and therefore, the findings will help hospitals in other regions to adopt some of the practices, like concentrating on local vendors, outsourcing, clustering, and maximum use of information technology as competitive factors that can improve the service and reduce the cost of operation. The paper suggests motivators and barriers to the use of ICT in logistics in the health care industry.

  11. Naval Undersea Warfare Center Division Newport utilities metering, Phase 1

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Carroll, D.M.

    Pacific Northwest Laboratory developed this report for the US Navy`s Naval Undersea Warfare Center Division Newport, Rhode Island (NUWC). The purpose of the report was to review options for metering electricity and steam used in the NUWC compound, and to make recommendations to NUWC for implementation under a follow-on project. An additional NUWC concern is a proposed rate change by the servicing utility, Newport Electric, which would make a significant shift from consumption to demand billing, and what effect that rate change would have on the NUWC utility budget. Automated, remote reading meters are available which would allow NUWC tomore » monitor its actual utility consumption and demand for both the entire NUWC compound and by end-use in individual buildings. Technology is available to perform the meter reads and manipulate the data using a personal computer with minimal staff requirement. This is not meant to mislead the reader into assuming that there is no requirement for routine preventive maintenance. All equipment requires routine maintenance to maintain its accuracy. While PNL reviewed the data collected during the site visit, however, it became obvious that significant opportunities exist for reducing the utility costs other than accounting for actual consumption and demand. Unit costs for both steam and electricity are unnecessarily high, and options are presented in this report for reducing them. Additionally, NUWC has an opportunity to undertake a comprehensive energy resource management program to significantly reduce its energy demand, consumption, and costs.« less

  12. Naval Undersea Warfare Center Division Newport utilities metering, Phase 1

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Carroll, D.M.

    Pacific Northwest Laboratory developed this report for the US Navy's Naval Undersea Warfare Center Division Newport, Rhode Island (NUWC). The purpose of the report was to review options for metering electricity and steam used in the NUWC compound, and to make recommendations to NUWC for implementation under a follow-on project. An additional NUWC concern is a proposed rate change by the servicing utility, Newport Electric, which would make a significant shift from consumption to demand billing, and what effect that rate change would have on the NUWC utility budget. Automated, remote reading meters are available which would allow NUWC tomore » monitor its actual utility consumption and demand for both the entire NUWC compound and by end-use in individual buildings. Technology is available to perform the meter reads and manipulate the data using a personal computer with minimal staff requirement. This is not meant to mislead the reader into assuming that there is no requirement for routine preventive maintenance. All equipment requires routine maintenance to maintain its accuracy. While PNL reviewed the data collected during the site visit, however, it became obvious that significant opportunities exist for reducing the utility costs other than accounting for actual consumption and demand. Unit costs for both steam and electricity are unnecessarily high, and options are presented in this report for reducing them. Additionally, NUWC has an opportunity to undertake a comprehensive energy resource management program to significantly reduce its energy demand, consumption, and costs.« less

  13. Influence of task switching costs on colony homeostasis

    NASA Astrophysics Data System (ADS)

    Jeanson, Raphaël; Lachaud, Jean-Paul

    2015-06-01

    In social insects, division of labour allows colonies to optimise the allocation of workers across all available tasks to satisfy colony requirements. The maintenance of stable conditions within colonies (homeostasis) requires that some individuals move inside the nest to monitor colony needs and execute unattended tasks. We developed a simple theoretical model to explore how worker mobility inside the nest and task switching costs influence the maintenance of stable levels of task-associated stimuli. Our results indicate that worker mobility in large colonies generates important task switching costs and is detrimental to colony homeostasis. Our study suggests that the balance between benefits and costs associated with the mobility of workers patrolling inside the nest depends on colony size. We propose that several species of ants with diverse life-history traits should be appropriate to test the prediction that the proportion of mobile workers should vary during colony ontogeny.

  14. Characterizing and Modeling the Cost of Rework in a Library of Reusable Software Components

    NASA Technical Reports Server (NTRS)

    Basili, Victor R.; Condon, Steven E.; ElEmam, Khaled; Hendrick, Robert B.; Melo, Walcelio

    1997-01-01

    In this paper we characterize and model the cost of rework in a Component Factory (CF) organization. A CF is responsible for developing and packaging reusable software components. Data was collected on corrective maintenance activities for the Generalized Support Software reuse asset library located at the Flight Dynamics Division of NASA's GSFC. We then constructed a predictive model of the cost of rework using the C4.5 system for generating a logical classification model. The predictor variables for the model are measures of internal software product attributes. The model demonstrates good prediction accuracy, and can be used by managers to allocate resources for corrective maintenance activities. Furthermore, we used the model to generate proscriptive coding guidelines to improve programming, practices so that the cost of rework can be reduced in the future. The general approach we have used is applicable to other environments.

  15. A new accounting system for financial balance based on personnel cost after the introduction of a DPC/DRG system.

    PubMed

    Nakagawa, Yoshiaki; Takemura, Tadamasa; Yoshihara, Hiroyuki; Nakagawa, Yoshinobu

    2011-04-01

    A hospital director must estimate the revenues and expenses not only in a hospital but also in each clinical division to determine the proper management strategy. A new prospective payment system based on the Diagnosis Procedure Combination (DPC/PPS) introduced in 2003 has made the attribution of revenues and expenses for each clinical department very complicated because of the intricate involvement between the overall or blanket component and a fee-for service (FFS). Few reports have so far presented a programmatic method for the calculation of medical costs and financial balance. A simple method has been devised, based on personnel cost, for calculating medical costs and financial balance. Using this method, one individual was able to complete the calculations for a hospital which contains 535 beds and 16 clinics, without using the central hospital computer system.

  16. Microfluidic CODES: a scalable multiplexed electronic sensor for orthogonal detection of particles in microfluidic channels.

    PubMed

    Liu, Ruxiu; Wang, Ningquan; Kamili, Farhan; Sarioglu, A Fatih

    2016-04-21

    Numerous biophysical and biochemical assays rely on spatial manipulation of particles/cells as they are processed on lab-on-a-chip devices. Analysis of spatially distributed particles on these devices typically requires microscopy negating the cost and size advantages of microfluidic assays. In this paper, we introduce a scalable electronic sensor technology, called microfluidic CODES, that utilizes resistive pulse sensing to orthogonally detect particles in multiple microfluidic channels from a single electrical output. Combining the techniques from telecommunications and microfluidics, we route three coplanar electrodes on a glass substrate to create multiple Coulter counters producing distinct orthogonal digital codes when they detect particles. We specifically design a digital code set using the mathematical principles of Code Division Multiple Access (CDMA) telecommunication networks and can decode signals from different microfluidic channels with >90% accuracy through computation even if these signals overlap. As a proof of principle, we use this technology to detect human ovarian cancer cells in four different microfluidic channels fabricated using soft lithography. Microfluidic CODES offers a simple, all-electronic interface that is well suited to create integrated, low-cost lab-on-a-chip devices for cell- or particle-based assays in resource-limited settings.

  17. Maximizing the spatial representativeness of NO2 monitoring data using a combination of local wind-based sectoral division and seasonal and diurnal correction factors.

    PubMed

    Donnelly, Aoife; Naughton, Owen; Misstear, Bruce; Broderick, Brian

    2016-10-14

    This article describes a new methodology for increasing the spatial representativeness of individual monitoring sites. Air pollution levels at a given point are influenced by emission sources in the immediate vicinity. Since emission sources are rarely uniformly distributed around a site, concentration levels will inevitably be most affected by the sources in the prevailing upwind direction. The methodology provides a means of capturing this effect and providing additional information regarding source/pollution relationships. The methodology allows for the division of the air quality data from a given monitoring site into a number of sectors or wedges based on wind direction and estimation of annual mean values for each sector, thus optimising the information that can be obtained from a single monitoring station. The method corrects for short-term data, diurnal and seasonal variations in concentrations (which can produce uneven weighting of data within each sector) and uneven frequency of wind directions. Significant improvements in correlations between the air quality data and the spatial air quality indicators were obtained after application of the correction factors. This suggests the application of these techniques would be of significant benefit in land-use regression modelling studies. Furthermore, the method was found to be very useful for estimating long-term mean values and wind direction sector values using only short-term monitoring data. The methods presented in this article can result in cost savings through minimising the number of monitoring sites required for air quality studies while also capturing a greater degree of variability in spatial characteristics. In this way, more reliable, but also more expensive monitoring techniques can be used in preference to a higher number of low-cost but less reliable techniques. The methods described in this article have applications in local air quality management, source receptor analysis, land-use regression mapping and modelling and population exposure studies.

  18. Partnering With NASA JSC for Community Research Needs; Collaborative and Student Opportunities via Jacobs and PSAMS Initiative

    NASA Technical Reports Server (NTRS)

    Danielson, Lisa; Draper, David

    2016-01-01

    NASA Johnson Space Center's (JSC's) Astromaterials Research and Exploration Science (ARES) Division houses a unique combination of laboratories and other assets for conducting cutting-edge planetary research. These facilities have been accessed for decades by outside scientists; over the past five years, the 16 full time contract research and technical staff members in our division have hosted a total of 223 visiting researchers, representing 35 institutions. In order to continue to provide this level of support to the planetary sciences community, and also expand our services and collaboration within the broader scientific community, we intend to submit a proposal to NASA specifically for facilities support and establishment of our laboratories as a collective, PSAMS, Planetary Sample Analyses and Mission Science. This initiative should result in substantial cost savings to PIs with NASA funding who wish to use our facilities. Another cost saving could be realized by aggregating visiting user experiments and analyses through COMPRES, which would be of particular interest to researchers in earth and material sciences. JSC is a recognized NASA center of excellence for curation, and in future will allow PIs and mission teams easy access to samples in Curation facilities that they have been approved to study. Our curation expertise could also be used for a collection of experimental run products that could be shared and distributed to COMPRES community members. These experimental run products could range from 1 bar controlled atmosphere furnace, piston cylinder, multi-anvil, CETUS (see companion abstract), to shocked products. Coordinated analyses of samples is one of the major strengths of our division, where a single sample can be prepared with minimal destruction for a variety of chemical and structural analyses, from macro to nano-scale.

  19. Reduced cost alternatives to premise wiring using ATM and microcellular technologies

    NASA Technical Reports Server (NTRS)

    Gejji, Raghvendra R.

    1993-01-01

    The cost of premises wiring keeps increasing due to personnel moves, new equipment, capacity upgrades etc. It would be desirable to have a wireless interface from the workstations to the fixed network, so as to minimize the wiring changes needed. New technologies such as microcellular personal communication systems are promising to bring down the cost of wireless communication. Another promising technology is Code Division Multiple Access (CDMA), which could dramatically increase the bandwidth available for wireless connections. In addition, Asynchronous Transfer Mode (ATM) technology is emerging as a technique for integrated management of voice, data, and video traffic on a single network. The focus of this investigation will be to assess the future utility of these new technologies for reducing the premise wiring cost at KSC. One of the issues to be studied is the cost comparison of 'old' versus 'new,' especially as time and technology progress. An additional issue for closer study is a feasible time-line for progress in technological capability.

  20. Streptococcus suis DivIVA Protein Is a Substrate of Ser/Thr Kinase STK and Involved in Cell Division Regulation

    PubMed Central

    Ni, Hua; Fan, Weiwei; Li, Chaolong; Wu, Qianqian; Hou, Hongfen; Hu, Dan; Zheng, Feng; Zhu, Xuhui; Wang, Changjun; Cao, Xiangrong; Shao, Zhu-Qing; Pan, Xiuzhen

    2018-01-01

    Streptococcus suis serotype 2 is an important swine pathogen and an emerging zoonotic agent that causes severe infections. Recent studies have reported a eukaryotic-like Ser/Thr protein kinase (STK) gene and characterized its role in the growth and virulence of different S. suis 2 strains. In the present study, phosphoproteomic analysis was adopted to identify substrates of the STK protein. Seven proteins that were annotated to participate in different cell processes were identified as potential substrates, which suggests the pleiotropic effects of stk on S. suis 2 by targeting multiple pathways. Among them, a protein characterized as cell division initiation protein (DivIVA) was further investigated. In vitro analysis demonstrated that the recombinant STK protein directly phosphorylates threonine at amino acid position 199 (Thr-199) of DivIVA. This effect could be completely abolished by the T199A mutation. To determine the specific role of DivIVA in growth and division, a divIVA mutant was constructed. The ΔdivIVA strain exhibited impaired growth and division, including lower viability, enlarged cell mass, asymmetrical division caused by aberrant septum, and extremely weak pathogenicity in a mouse infection model. Collectively, our results reveal that STK regulates the cell growth and virulence of S. suis 2 by targeting substrates that are involved in different biological pathways. The inactivation of DivIVA leads to severe defects in cell division and strongly attenuates pathogenicity, thereby indicating its potential as a molecular drug target against S. suis. PMID:29616196

  1. The costs in provision of haemodialysis in a developing country: a multi-centered study.

    PubMed

    Ranasinghe, Priyanga; Perera, Yashasvi S; Makarim, Mohamed F M; Wijesinghe, Aruna; Wanigasuriya, Kamani

    2011-09-06

    Chronic Kidney Disease is a major public health problem worldwide with enormous cost burdens on health care systems in developing countries. We aimed to provide a detailed analysis of the processes and costs of haemodialysis in Sri Lanka and provide a framework for modeling similar financial audits. This prospective study was conducted at haemodialysis units of three public and two private hospitals in Sri Lanka for two months in June and July 2010. Cost of drugs and consumables for the three public hospitals were obtained from the price list issued by the Medical Supplies Division of the Department of Health Services, while for the two private hospitals they were obtained from financial departments of the respective hospitals. Staff wages were obtained from the hospital chief accountant/chief financial officers. The cost of electricity and water per month was calculated directly with the assistance of expert engineers. An apportion was done from the total hospital costs of administration, cleaning services, security, waste disposal and, laundry and sterilization for each unit. The total number of dialysis sessions (hours) at the five hospitals for June and July were 3341 (12959) and 3386 (13301) respectively. Drug and consumables costs accounted for 70.4-84.9% of the total costs, followed by the wages of the nursing staff at each unit (7.8-19.7%). The mean cost of a dialysis session in Sri Lanka was LKR 6,377 (US$ 56). The annual cost of haemodialysis for a patient with chronic renal failure undergoing 2-3 dialysis session of four hours duration per week was LKR 663,208-994,812 (US$ 5,869-8,804). At one hospital where facilities are available for the re-use of dialyzers (although not done during study period) the cost of consumables would have come down from LKR 5,940,705 to LKR 3,368,785 (43% reduction) if the method was adopted, reducing costs of haemodialysis per hour from LKR 1,327 at present to LKR 892 (33% reduction). This multi-centered study demonstrated that the costs of haemodialysis in a developing country remained significantly lower compared to developed countries. However, it still places a significant burden on the health care sector, whilst possibility of further cost reduction exists.

  2. The costs in provision of haemodialysis in a developing country: A multi-centered study

    PubMed Central

    2011-01-01

    Background Chronic Kidney Disease is a major public health problem worldwide with enormous cost burdens on health care systems in developing countries. We aimed to provide a detailed analysis of the processes and costs of haemodialysis in Sri Lanka and provide a framework for modeling similar financial audits. Methods This prospective study was conducted at haemodialysis units of three public and two private hospitals in Sri Lanka for two months in June and July 2010. Cost of drugs and consumables for the three public hospitals were obtained from the price list issued by the Medical Supplies Division of the Department of Health Services, while for the two private hospitals they were obtained from financial departments of the respective hospitals. Staff wages were obtained from the hospital chief accountant/chief financial officers. The cost of electricity and water per month was calculated directly with the assistance of expert engineers. An apportion was done from the total hospital costs of administration, cleaning services, security, waste disposal and, laundry and sterilization for each unit. Results The total number of dialysis sessions (hours) at the five hospitals for June and July were 3341 (12959) and 3386 (13301) respectively. Drug and consumables costs accounted for 70.4-84.9% of the total costs, followed by the wages of the nursing staff at each unit (7.8-19.7%). The mean cost of a dialysis session in Sri Lanka was LKR 6,377 (US$ 56). The annual cost of haemodialysis for a patient with chronic renal failure undergoing 2-3 dialysis session of four hours duration per week was LKR 663,208-994,812 (US$ 5,869-8,804). At one hospital where facilities are available for the re-use of dialyzers (although not done during study period) the cost of consumables would have come down from LKR 5,940,705 to LKR 3,368,785 (43% reduction) if the method was adopted, reducing costs of haemodialysis per hour from LKR 1,327 at present to LKR 892 (33% reduction). Conclusions This multi-centered study demonstrated that the costs of haemodialysis in a developing country remained significantly lower compared to developed countries. However, it still places a significant burden on the health care sector, whilst possibility of further cost reduction exists. PMID:21896190

  3. Low-cost CWDM transmitter package

    NASA Astrophysics Data System (ADS)

    Bhandarkar, Navin; Castillega, Jaime

    2005-03-01

    A low-cost coarse-wavelength-division multiplexer (CWDM) transmitter that combines four channels (wavelengths) in the infrared spectrum (~1310 nm) in a small form-factor un-cooled package is demonstrated. The package utilizes precision molded optics to multiplex beams from four grating-outcoupled surface-emitting (GSE) lasers into a single beam suitable for coupling into multimode fiber. This paper summarizes the optical and opto-mechanical design, fabrication and assembly of prototypes, and optical, thermal and electrical measurement results of the prototypes. This unique design enables multiplexing of wavelengths without the use of filters, waveguides, couplers and fiber splicing. Commercial fabrication and alignment technology is used to manufacture the package, resulting in a more robust, reliable and low-cost transmitter. The transmitter package is enabled by the unique characteristics of the long-wavelength GSE laser.

  4. Operational numerical weather prediction on the CYBER 205 at the National Meteorological Center

    NASA Technical Reports Server (NTRS)

    Deaven, D.

    1984-01-01

    The Development Division of the National Meteorological Center (NMC), having the responsibility of maintaining and developing the numerical weather forecasting systems of the center, is discussed. Because of the mission of NMC data products must be produced reliably and on time twice daily free of surprises for forecasters. Personnel of Development Division are in a rather unique situation. They must develop new advanced techniques for numerical analysis and prediction utilizing current state-of-the-art techniques, and implement them in an operational fashion without damaging the operations of the center. With the computational speeds and resources now available from the CYBER 205, Development Division Personnel will be able to introduce advanced analysis and prediction techniques into the operational job suite without disrupting the daily schedule. The capabilities of the CYBER 205 are discussed.

  5. Publications - GMC 309 | Alaska Division of Geological & Geophysical

    Science.gov Websites

    in the North Aleutian COST # 1 well as follows: cuttings composited (15,700' - 16,800') as one sample , and core composited (16,006.0' - 16,029' and 16,701.2' - 16,720') as one sample Authors: U.S. Minerals ') as one sample, and core composited (16,006.0' - 16,029' and 16,701.2' - 16,720') as one sample

  6. KSC-04PD-0956

    NASA Technical Reports Server (NTRS)

    2004-01-01

    KENNEDY SPACE CENTER, FLA. Mario Busacca, with the Safety, Occupational Health and Environmental Division, handles a snake at one of the exhibits for KSCs annual Environmental and Energy Awareness Week, held April 20-22. Presentations included Chemistry Safety, Cost-Effective Solar Applications, Non-Native Invasive Plant Identification and Control, Energy Efficient Lighting Systems, and Historical Changes in KSCs Ecosystems. The slogan for this years event was Today's Conservation Defines Tomorrow's Future.

  7. Face masks and basketball: NCAA division I consumer trends and a review of over-the-counter face masks.

    PubMed

    Gandy, Jessica R; Fossett, Lela; Wong, Brian J F

    2016-05-01

    This study aims to: 1) determine the current consumer trends of over-the-counter (OTC) and custom-made face mask usage among National Collegiate Athletic Association (NCAA) Division I athletic programs; and 2) provide a literature review of OTC face guards and a classified database. Literature review and survey. Consumer trends were obtained by contacting all 352 NCAA Division I programs. Athletic trainers present in the office when called answered the following questions: 1) "When an athlete breaks his or her nose, is a custom or generic face guard used?" and 2) "What brand is the generic face guard that is used?" Data was analyzed to determine trends among athletic programs. Also, a database of OTC devices available was generated using PubMed, Google, and manufacturer Web sites. Among the 352 NCAA Division I athletic programs, 254 programs participated in the survey (72% response rate). The majority preferred custom-made guards (46%). Disadvantages included high cost and slow manufacture turnaround time. Only 20% of the programs strictly used generic brands. For the face mask database, 10 OTC products were identified and classified into four categories based on design, with pricing ranging between $35.99 and $69.95. Only a handful of face masks exist for U.S. consumers, but none of them have been reviewed or classified by product design, sport application, price, and collegiate consumer use. This project details usage trends among NCAA Division I athletic programs and provides a list of available devices that can be purchased to protect the nose and face during sports. NA. Laryngoscope, 126:1054-1060, 2016. © 2015 The American Laryngological, Rhinological and Otological Society, Inc.

  8. Petroleum marketing monthly, May 1994

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1994-05-26

    The Petroleum Marketing Monthly (PMM) provides information and statistical data on a variety of crude oils and refined petroleum products. The publication presents statistics on crude oil costs and refined petroleum products sales for use by industry, government, private sector analysts, educational institutions, and consumers. Data on crude oil include the domestic first purchase price, the f.o.b. and landed cost of imported crude oil, petroleum product sales data include motor gasoline, distillates, residuals, aviation fuels, kerosene, and propane. The Petroleum Marketing Division, Office of Oil and Gas, Energy Information Administration ensures the accuracy, quality, and confidentiality of the published datamore » in the Petroleum Marketing Monthly.« less

  9. District of Columbia Public Schools: Availability of Funds and the Cost of FY 1997 Roof Projects. Testimony before the Subcommittee on Oversight of Government Management, Restructuring and the District of Columbia Committee on Governmental Affairs, U.S. Senate. Statement of Gloria L. Jaimon, Director, Health, Education, and Human Services Accounting and Financial Management Issues, Accounting and Information Management Division.

    ERIC Educational Resources Information Center

    General Accounting Office, Washington, DC. Accounting and Information Management Div.

    This document presents the results of a review of the District of Columbia Public Schools' (DCPS) efforts to repair school roofs during the summer of 1997. The statement details when funds were made available to pay for roof repairs, the costs of the roof repairs, and additional roofs to be fixed in fiscal year 1998 and beyond. Sufficient funding…

  10. Bayesian Research at the NASA Ames Research Center,Computational Sciences Division

    NASA Technical Reports Server (NTRS)

    Morris, Robin D.

    2003-01-01

    NASA Ames Research Center is one of NASA s oldest centers, having started out as part of the National Advisory Committee on Aeronautics, (NACA). The site, about 40 miles south of San Francisco, still houses many wind tunnels and other aviation related departments. In recent years, with the growing realization that space exploration is heavily dependent on computing and data analysis, its focus has turned more towards Information Technology. The Computational Sciences Division has expanded rapidly as a result. In this article, I will give a brief overview of some of the past and present projects with a Bayesian content. Much more than is described here goes on with the Division. The web pages at http://ic.arc. nasa.gov give more information on these, and the other Division projects.

  11. Development of spatial data guidelines and standards: spatial data set documentation to support hydrologic analysis in the U.S. Geological Survey

    USGS Publications Warehouse

    Fulton, James L.

    1992-01-01

    Spatial data analysis has become an integral component in many surface and sub-surface hydrologic investigations within the U.S. Geological Survey (USGS). Currently, one of the largest costs in applying spatial data analysis is the cost of developing the needed spatial data. Therefore, guidelines and standards are required for the development of spatial data in order to allow for data sharing and reuse; this eliminates costly redevelopment. In order to attain this goal, the USGS is expanding efforts to identify guidelines and standards for the development of spatial data for hydrologic analysis. Because of the variety of project and database needs, the USGS has concentrated on developing standards for documenting spatial sets to aid in the assessment of data set quality and compatibility of different data sets. An interim data set documentation standard (1990) has been developed that provides a mechanism for associating a wide variety of information with a data set, including data about source material, data automation and editing procedures used, projection parameters, data statistics, descriptions of features and feature attributes, information on organizational contacts lists of operations performed on the data, and free-form comments and notes about the data, made at various times in the evolution of the data set. The interim data set documentation standard has been automated using a commercial geographic information system (GIS) and data set documentation software developed by the USGS. Where possible, USGS developed software is used to enter data into the data set documentation file automatically. The GIS software closely associates a data set with its data set documentation file; the documentation file is retained with the data set whenever it is modified, copied, or transferred to another computer system. The Water Resources Division of the USGS is continuing to develop spatial data and data processing standards, with emphasis on standards needed to support hydrologic analysis, hydrologic data processing, and publication of hydrologic thermatic maps. There is a need for the GIS vendor community to develop data set documentation tools similar to those developed by the USGS, or to incorporate USGS developed tools in their software.

  12. Identifying and Promoting Transition Evidence-Based Practices and Predictors of Success: A Position Paper of the Division on Career Development and Transition

    ERIC Educational Resources Information Center

    Mazzotti, Valerie L.; Rowe, Dawn A.; Cameto, Renee; Test, David W.; Morningstar, Mary E.

    2013-01-01

    This position paper describes the Division of Career Development and Transition's stance and recommendations for identifying and promoting secondary transition evidence-based practices and predictors of postschool success for students with disabilities. Recommendations for experimental research, correlational research, and secondary analysis of…

  13. Managing Change in the Student Affairs Divisions of Higher Education Institutions

    ERIC Educational Resources Information Center

    Lumadi, T. E.; Mampuru, K. C.

    2010-01-01

    In any institution of higher education the student affairs division is an ever-changing environment that necessitates an appropriate management approach. In view of this situation it was deemed necessary to identify a change model that would successfully manage change in student affairs. A literature review was done and an analysis of some…

  14. An Analysis of Computational Errors in the Use of Division Algorithms by Fourth-Grade Students.

    ERIC Educational Resources Information Center

    Stefanich, Greg P.; Rokusek, Teri

    1992-01-01

    Presents a study that analyzed errors made by randomly chosen fourth grade students (25 of 57) while using the division algorithm and investigated the effect of remediation on identified systematic errors. Results affirm that error pattern diagnosis and directed remediation lead to new learning and long-term retention. (MDH)

  15. An Analysis of Characteristics of Selected Unemployment Insurance Claimants with Implications for Vocational Education.

    ERIC Educational Resources Information Center

    Arkansas State Employment Security Div., Little Rock.

    In 1975, the Arkansas Employment Security Division conducted a telephone survey of 15,675 unemployed insurance claimants at the request of the Division of Vocational Education of the State Department of Education. The purpose of the survey was threefold: (1) to obtain detailed social and economic characteristics of the claimants, (2) to determine…

  16. Analytical capabilities and services of Lawrence Livermore Laboratory's General Chemistry Division. [Methods available at Lawrence Livermore

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gutmacher, R.; Crawford, R.

    This comprehensive guide to the analytical capabilities of Lawrence Livermore Laboratory's General Chemistry Division describes each analytical method in terms of its principle, field of application, and qualitative and quantitative uses. Also described are the state and quantity of sample required for analysis, processing time, available instrumentation, and responsible personnel.

  17. 76 FR 34986 - Agency Procedure for Disclosure of Documents and Information in the Enforcement Process

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-15

    ... referrals to the Office of General Counsel from the Commission's Reports Analysis Division or Audit Division... hearing before the Commission prior to the Commission's adoption of a Final Audit Report,\\11\\ and (3) a.../2009/notice_2009-11.pdf . \\11\\ See Procedural Rules for Audit Hearings, 74 FR 33140 (July 10, 2009...

  18. Relational Reasoning about Numbers and Operations--Foundation for Calculation Strategy Use in Multi-Digit Multiplication and Division

    ERIC Educational Resources Information Center

    Schulz, Andreas

    2018-01-01

    Theoretical analysis of whole number-based calculation strategies and digit-based algorithms for multi-digit multiplication and division reveals that strategy use includes two kinds of reasoning: reasoning about the relations between numbers and reasoning about the relations between operations. In contrast, algorithms aim to reduce the necessary…

  19. Theatre for Change: An Analysis of Two Performances by Women in Mundemba Sub-Division.

    ERIC Educational Resources Information Center

    Tanyi-Tang, Anne

    2001-01-01

    Contends that theatre has the power to induce oppressors to change their attitudes permanently towards the groups they oppress. Describes theatrical performances by women in Mundemba Sub-Division, Cameroon, which created lasting changes in men's attitudes. Concludes that theatre calls for sociocultural and economic changes and it has the power to…

  20. Demographic Analysis of the Students in the Allied Health Division: 1976-80.

    ERIC Educational Resources Information Center

    Compton Community Coll., CA.

    A demographic profile is presented of the 710 students who were enrolled in Compton Community College's Allied Health Division during the five-year period from 1976 through 1980. After reviewing the limitations of the study, the report looks at annual and total enrollments in six program areas: associate degree nursing, vocational nursing,…

  1. [The aging process and work: a case study in the maintenance engineering division of a public hospital in the city of São Paulo, Brazil].

    PubMed

    Sato, Andrea Toshye; Barros, Juliana de Oliveira; Jardim, Tatiana de Andrade; Ratier, Ana Paula Pelegrini; Lancman, Selma

    2017-11-06

    This study aimed to identify and analyze the relations between aging and work. This was a case study in the maintenance engineering division of a high-complexity hospital in the city of São Paulo, Brazil. In September and October 2015, 16 semi-structured interviews were held with the division heads and other workers with a minimum age of 50 years. The data were analyzed with thematic content analysis. Although the workers experienced difficulties resulting from the aging process, these did not prevent them from performing their work activities, since they developed strategies through their knowhow to compensate for their functional losses and/or declines. Still, they felt limited and demotivated due to the poor working conditions, outsourcing of the division, and the prevailing workload organization. Thus, in this division, the working conditions and organization had more impact than the aging process on the individuals' daily work routine.

  2. MANTECH project book

    NASA Astrophysics Data System (ADS)

    The effective integration of processes, systems, and procedures used in the production of aerospace systems using computer technology is managed by the Integration Technology Division (MTI). Under its auspices are the Information Management Branch, which is actively involved with information management, information sciences and integration, and the Implementation Branch, whose technology areas include computer integrated manufacturing, engineering design, operations research, and material handling and assembly. The Integration Technology Division combines design, manufacturing, and supportability functions within the same organization. The Processing and Fabrication Division manages programs to improve structural and nonstructural materials processing and fabrication. Within this division, the Metals Branch directs the manufacturing methods program for metals and metal matrix composites processing and fabrication. The Nonmetals Branch directs the manufacturing methods programs, which include all manufacturing processes for producing and utilizing propellants, plastics, resins, fibers, composites, fluid elastomers, ceramics, glasses, and coatings. The objective of the Industrial Base Analysis Division is to act as focal point for the USAF industrial base program for productivity, responsiveness, and preparedness planning.

  3. Activity and Accumulation of Cell Division-Promoting Phenolics in Tobacco Tissue Cultures 1

    PubMed Central

    Teutonico, Rita A.; Dudley, Matthew W.; Orr, John D.; Lynn, David G.; Binns, Andrew N.

    1991-01-01

    Dehydrodiconiferyl alcohol glucosides (DCGs) are derivatives of the phenylpropanoid pathway that have been isolated from Catharansus roseus L. (Vinca rosea) crown gall tumors. Fractions containing purified DCGs have been shown previously to promote the growth of cytokinin-requiring tissues of tobacco in the absence of exogenous cytokinins. In this study, we utilized synthetic DCG isomers to confirm the cell division-promoting activity of DCG isomers A and B and show that they neither promote shoot meristem initiation on Nicotiana tabacum L., cv Havana 425, leaf explants nor induce betacyanin synthesis in amaranth seedlings. Analysis of cultured tobacco pith tissue demonstrated that DCG accumulation was stimulated by cytokinin treatment and correlated with cytokinin-induced cell division. Thus, the accumulation of metabolites that could replace cytokinin in cell division bioassays is stimulated by cytokinins. These data support the model that DCGs are a component of a cytokinin-mediated regulatory circuit controlling cell division. ImagesFigure 2 PMID:16668384

  4. An optimization model for energy generation and distribution in a dynamic facility

    NASA Technical Reports Server (NTRS)

    Lansing, F. L.

    1981-01-01

    An analytical model is described using linear programming for the optimum generation and distribution of energy demands among competing energy resources and different economic criteria. The model, which will be used as a general engineering tool in the analysis of the Deep Space Network ground facility, considers several essential decisions for better design and operation. The decisions sought for the particular energy application include: the optimum time to build an assembly of elements, inclusion of a storage medium of some type, and the size or capacity of the elements that will minimize the total life-cycle cost over a given number of years. The model, which is structured in multiple time divisions, employ the decomposition principle for large-size matrices, the branch-and-bound method in mixed-integer programming, and the revised simplex technique for efficient and economic computer use.

  5. Estimating the incidence, prevalence and true cost of asthma in the UK: secondary analysis of national stand-alone and linked databases in England, Northern Ireland, Scotland and Wales-a study protocol.

    PubMed

    Mukherjee, Mome; Gupta, Ramyani; Farr, Angela; Heaven, Martin; Stoddart, Andrew; Nwaru, Bright I; Fitzsimmons, Deborah; Chamberlain, George; Bandyopadhyay, Amrita; Fischbacher, Colin; Dibben, Christopher; Shields, Michael; Phillips, Ceri; Strachan, David; Davies, Gwyneth; McKinstry, Brian; Sheikh, Aziz

    2014-11-04

    Asthma is now one of the most common long-term conditions in the UK. It is therefore important to develop a comprehensive appreciation of the healthcare and societal costs in order to inform decisions on care provision and planning. We plan to build on our earlier estimates of national prevalence and costs from asthma by filling the data gaps previously identified in relation to healthcare and broadening the field of enquiry to include societal costs. This work will provide the first UK-wide estimates of the costs of asthma. In the context of asthma for the UK and its member countries (ie, England, Northern Ireland, Scotland and Wales), we seek to: (1) produce a detailed overview of estimates of incidence, prevalence and healthcare utilisation; (2) estimate health and societal costs; (3) identify any remaining information gaps and explore the feasibility of filling these and (4) provide insights into future research that has the potential to inform changes in policy leading to the provision of more cost-effective care. Secondary analyses of data from national health surveys, primary care, prescribing, emergency care, hospital, mortality and administrative data sources will be undertaken to estimate prevalence, healthcare utilisation and outcomes from asthma. Data linkages and economic modelling will be undertaken in an attempt to populate data gaps and estimate costs. Separate prevalence and cost estimates will be calculated for each of the UK-member countries and these will then be aggregated to generate UK-wide estimates. Approvals have been obtained from the NHS Scotland Information Services Division's Privacy Advisory Committee, the Secure Anonymised Information Linkage Collaboration Review System, the NHS South-East Scotland Research Ethics Service and The University of Edinburgh's Centre for Population Health Sciences Research Ethics Committee. We will produce a report for Asthma-UK, submit papers to peer-reviewed journals and construct an interactive map. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

  6. The 30/20 Gigahertz transponder study. [wideband multichannel transponders for a communications satellite

    NASA Technical Reports Server (NTRS)

    1980-01-01

    Design features and performance parameters are described for three types of wideband multiple channel satellite transponders for use in a 30/20 GHz communications satellite, which provides high data rate trunking service to ten ground station terminals. The three types of transponder are frequency division multiplex (FDM), time division multiplex (TDM), and a hybrid transponder using a combination of FDM and TDM techniques. The wideband multiple beam trunking concept, the traffic distribution between the trunking terminals, and system design constraints are discussed. The receiver front end design, the frequency conversion scheme, and the local oscillator design are described including the thermal interface between the transponders and the satellite. The three designs are compared with regard to performance, weight, power, cost and initial technology. Simplified block diagrams of the baseline transponder designs are included.

  7. Meeting the future metro network challenges and requirements by adopting programmable S-BVT with direct-detection and PDM functionality

    NASA Astrophysics Data System (ADS)

    Nadal, Laia; Svaluto Moreolo, Michela; Fàbrega, Josep M.; Vílchez, F. Javier

    2017-07-01

    In this paper, we propose an advanced programmable sliceable-bandwidth variable transceiver (S-BVT) with polarization division multiplexing (PDM) capability as a key enabler to fulfill the requirements for future 5G networks. Thanks to its cost-effective optoelectronic front-end based on orthogonal frequency division multiplexing (OFDM) technology and direct-detection (DD), the proposed S-BVT becomes suitable for next generation highly flexible and scalable metro networks. Polarization beam splitters (PBSs) and controllers (PCs), available on-demand, are included at the transceivers and at the network nodes, further enhancing the system flexibility and promoting an efficient use of the spectrum. 40G-100G PDM transmission has been experimentally demonstrated, within a 4-node photonic mesh network (ADRENALINE testbed), implementing a simplified equalization process.

  8. Dynamic segment shared protection for multicast traffic in meshed wavelength-division-multiplexing optical networks

    NASA Astrophysics Data System (ADS)

    Liao, Luhua; Li, Lemin; Wang, Sheng

    2006-12-01

    We investigate the protection approach for dynamic multicast traffic under shared risk link group (SRLG) constraints in meshed wavelength-division-multiplexing optical networks. We present a shared protection algorithm called dynamic segment shared protection for multicast traffic (DSSPM), which can dynamically adjust the link cost according to the current network state and can establish a primary light-tree as well as corresponding SRLG-disjoint backup segments for a dependable multicast connection. A backup segment can efficiently share the wavelength capacity of its working tree and the common resources of other backup segments based on SRLG-disjoint constraints. The simulation results show that DSSPM not only can protect the multicast sessions against a single-SRLG breakdown, but can make better use of the wavelength resources and also lower the network blocking probability.

  9. Incidence of chronic groin pain following open mesh inguinal hernia repair, and effect of elective division of the ilioinguinal nerve: meta-analysis of randomized controlled trials.

    PubMed

    Charalambous, M P; Charalambous, C P

    2018-06-01

    Chronic post-operative groin pain is a substantial complication following open mesh inguinal hernia repair. The exact cause of this pain is still unclear, but entrapment or trauma of the ilioinguinal nerve may have a role to play. Elective division of this nerve during hernia repair has been proposed in an attempt to reduce the incidence of chronic groin pain. We performed a meta-analysis of nine randomized controlled trials comparing preservation versus elective division of the ilioinguinal nerve during this operation. A substantial proportion of patients having open mesh inguinal hernia repair experience chronic groin pain when the ilioinguinal nerve is preserved (estimated rate of 9.4% at 6 months and 4.8% at 1 year). Elective division of the nerve resulted in a significant reduction of groin pain at 6-months post-surgery (RR 0.47, p = 0.02), including moderate/severe pain (RR 0.57, p = 0.01). However, division of the nerve also resulted in an increase of subjective groin numbness at this time point (RR 1.55, p = 0.06). At 12-month post-surgery, the beneficial effect of nerve division on chronic pain was reduced, with no significant difference in the rates of overall groin pain (RR 0.69, p = 0.38), or of moderate-to-severe groin pain (RR 0.99, p = 0.98) between the two groups. The prevalence of groin numbness was also similar between the two groups at 12-month post-surgery (RR 0.79, p = 0.48). Routine elective division of the ilioinguinal nerve during open mesh inguinal hernia repair does not significantly reduce chronic groin pain beyond 6 months, and may result in increased rates of groin numbness, especially in the first 6-months post-surgery.

  10. High- and low-level hierarchical classification algorithm based on source separation process

    NASA Astrophysics Data System (ADS)

    Loghmari, Mohamed Anis; Karray, Emna; Naceur, Mohamed Saber

    2016-10-01

    High-dimensional data applications have earned great attention in recent years. We focus on remote sensing data analysis on high-dimensional space like hyperspectral data. From a methodological viewpoint, remote sensing data analysis is not a trivial task. Its complexity is caused by many factors, such as large spectral or spatial variability as well as the curse of dimensionality. The latter describes the problem of data sparseness. In this particular ill-posed problem, a reliable classification approach requires appropriate modeling of the classification process. The proposed approach is based on a hierarchical clustering algorithm in order to deal with remote sensing data in high-dimensional space. Indeed, one obvious method to perform dimensionality reduction is to use the independent component analysis process as a preprocessing step. The first particularity of our method is the special structure of its cluster tree. Most of the hierarchical algorithms associate leaves to individual clusters, and start from a large number of individual classes equal to the number of pixels; however, in our approach, leaves are associated with the most relevant sources which are represented according to mutually independent axes to specifically represent some land covers associated with a limited number of clusters. These sources contribute to the refinement of the clustering by providing complementary rather than redundant information. The second particularity of our approach is that at each level of the cluster tree, we combine both a high-level divisive clustering and a low-level agglomerative clustering. This approach reduces the computational cost since the high-level divisive clustering is controlled by a simple Boolean operator, and optimizes the clustering results since the low-level agglomerative clustering is guided by the most relevant independent sources. Then at each new step we obtain a new finer partition that will participate in the clustering process to enhance semantic capabilities and give good identification rates.

  11. EGenBio: A Data Management System for Evolutionary Genomics and Biodiversity

    PubMed Central

    Nahum, Laila A; Reynolds, Matthew T; Wang, Zhengyuan O; Faith, Jeremiah J; Jonna, Rahul; Jiang, Zhi J; Meyer, Thomas J; Pollock, David D

    2006-01-01

    Background Evolutionary genomics requires management and filtering of large numbers of diverse genomic sequences for accurate analysis and inference on evolutionary processes of genomic and functional change. We developed Evolutionary Genomics and Biodiversity (EGenBio; ) to begin to address this. Description EGenBio is a system for manipulation and filtering of large numbers of sequences, integrating curated sequence alignments and phylogenetic trees, managing evolutionary analyses, and visualizing their output. EGenBio is organized into three conceptual divisions, Evolution, Genomics, and Biodiversity. The Genomics division includes tools for selecting pre-aligned sequences from different genes and species, and for modifying and filtering these alignments for further analysis. Species searches are handled through queries that can be modified based on a tree-based navigation system and saved. The Biodiversity division contains tools for analyzing individual sequences or sequence alignments, whereas the Evolution division contains tools involving phylogenetic trees. Alignments are annotated with analytical results and modification history using our PRAED format. A miscellaneous Tools section and Help framework are also available. EGenBio was developed around our comparative genomic research and a prototype database of mtDNA genomes. It utilizes MySQL-relational databases and dynamic page generation, and calls numerous custom programs. Conclusion EGenBio was designed to serve as a platform for tools and resources to ease combined analysis in evolution, genomics, and biodiversity. PMID:17118150

  12. NASA Johnson Space Center's Planetary Sample Analysis and Mission Science (PSAMS) Laboratory: A National Facility for Planetary Research

    NASA Technical Reports Server (NTRS)

    Draper, D. S.

    2016-01-01

    NASA Johnson Space Center's (JSC's) Astromaterials Research and Exploration Science (ARES) Division, part of the Exploration Integration and Science Directorate, houses a unique combination of laboratories and other assets for conducting cutting edge planetary research. These facilities have been accessed for decades by outside scientists, most at no cost and on an informal basis. ARES has thus provided substantial leverage to many past and ongoing science projects at the national and international level. Here we propose to formalize that support via an ARES/JSC Plane-tary Sample Analysis and Mission Science Laboratory (PSAMS Lab). We maintain three major research capa-bilities: astromaterial sample analysis, planetary process simulation, and robotic-mission analog research. ARES scientists also support planning for eventual human ex-ploration missions, including astronaut geological training. We outline our facility's capabilities and its potential service to the community at large which, taken together with longstanding ARES experience and expertise in curation and in applied mission science, enable multi-disciplinary planetary research possible at no other institution. Comprehensive campaigns incorporating sample data, experimental constraints, and mission science data can be conducted under one roof.

  13. Cell Division in genus Corynebacterium: protein-protein interaction and molecular docking of SepF and FtsZ in the understanding of cytokinesis in pathogenic species.

    PubMed

    Oliveira, Alberto F; Folador, Edson L; Gomide, Anne C P; Goes-Neto, Aristóteles; Azevedo, Vasco A C; Wattam, Alice R

    2018-02-15

    The genus Corynebacterium includes species of great importance in medical, veterinary and biotechnological fields. The genus-specific families (PLfams) from PATRIC have been used to observe conserved proteins associated to all species. Our results showed a large number of conserved proteins that are associated with the cellular division process. Was not observe in our results other proteins like FtsA and ZapA that interact with FtsZ. Our findings point that SepF overlaps the function of this proteins explored by molecular docking, protein-protein interaction and sequence analysis. Transcriptomic analysis showed that these two (Sepf and FtsZ) proteins can be expressed in different conditions together. The work presents novelties on molecules participating in the cell division event, from the interaction of FtsZ and SepF, as new therapeutic targets.

  14. A time for change: an exploration of attitudes toward part-time work in academia among women internists and their division chiefs.

    PubMed

    Harrison, Rebecca A; Gregg, Jessica L

    2009-01-01

    Increasing numbers of clinicians desire part-time work, and many will opt out of academic medicine if the barriers to part-time work are too great. Purposeful sampling was used to investigate the experiences of part-time academic physicians and their division leaders to understand (1) how each identified the negative and positive consequences of part-time work, and (2) how each conceptualize part-time work. In 2004, the authors interviewed the Society of General Medicine Horn Scholars Program applicants and their division chiefs from the 2001 and 2004 award cycles and performed a qualitative analysis of the one- to two-hour audiotaped interviews. Seven out of nine eligible applicants and six of seven division chiefs participated. All applicants were female junior faculty clinician educators in academic internal medicine from seven institutions. All division chiefs were male full-time faculty members. Both applicants and division chiefs identified multiple specific negative and positive consequences of part-time work. Analysis of interviews suggested that both groups tended to frame part-time work as a decision to "work less" or to "work differently." Self-reflection and articulation of values helped some faculty determine where they derive the greatest happiness and fulfillment personally and professionally. As more academics seek work-life balance and consider part-time work as a tool to achieve that balance, academic medicine will be challenged to develop creative models for integrating successful part-time physicians, or it will lose that segment of the workforce. This study's findings suggest that one such model may require that physicians and their leaders reconceptualize work altogether.

  15. Domestic Division of Labor and Its Relationship to Sex Role Orientation and Work Attitudes in Working Couples.

    ERIC Educational Resources Information Center

    Gunter, Nancy C.; Gunter, B. G.

    This study examined the relationship of gender, sex role orientation, and work attitudes to the domestic division of labor in 141 working couples. Couples completed the Bem Sex Role Inventory and a questionnaire on the performance of household tasks. Analysis of variance (ANOVA) confirmed that working women performed a disproportionately larger…

  16. Time Based Subjective Evaluations of Seated Cushion Comfort

    DTIC Science & Technology

    2007-04-01

    Protection Division Biomechanics Branch Hilary L. Gallagher, MS Oak Ridge Institute for Science and Education (ORISE) 1299 Bethel Valley Road...MONITOR’S REPORT NUMBER(S) Biosciences and Protection Division AFRL-HE-WP-TR-2007-0062 Biomechanics Branch Wright-Patterson AFB OH 45433-7947 12...13 iv PREFACE The cushion comfort tests and data analysis described in this report were accomplished by the Biomechanics

  17. Analysis of Digital Marketing in NCAA Division I and NCAA Division II Colleges of Education and Colleges of Business

    ERIC Educational Resources Information Center

    Vranes, Jason

    2017-01-01

    Higher education institutions have become big businesses that must thrive in the open marketplace to stay viable for the upcoming generation of students. As Generation Z students begin to populate campuses around the country, senior leaders need to possess tools to effectively solicit them. Reaching these online "digital natives" equates…

  18. Proceedings of the Annual Meeting of the Association for Education in Journalism and Mass Communication (86th, Kansas City, Missouri, July 30-August 2, 2003). Media Management & Economics Division.

    ERIC Educational Resources Information Center

    2003

    The Media Management & Economics Division of the proceedings contains the following 11 papers: "Supervisor Leadership Behavior's Effect on Television Newsworker Professionalism" (Natalie Corey); "Applying the Structure-Conduct-Performance Framework in the Media Industry Analysis" (W. Wayne Fu); "The Bigger, the Better?…

  19. An Analysis of How Participating in a NCAA Division I-A Football Program Impacts the Christian Faith Development of Student Athletes

    ERIC Educational Resources Information Center

    Epting, James B., Jr.

    2013-01-01

    The current study described and analyzed the perspectives of traditional-aged college student-athletes who participated in National Collegiate Athletic Association (NCAA) Division I football regarding the impact the sport had on Christian faith development. The study entailed a qualitative research method approach using in-depth semi-structured…

  20. 75 FR 42088 - Policy Statement Establishing a Pilot Program for Requesting Consideration of Legal Questions by...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-20

    ... program for a procedure to provide a means for persons and entities to have a legal question considered by... means for persons and entities to have a legal question considered by the Commission earlier in both the... includes the Report Analysis Division and the Audit Division) requests that a person or entity take...

Top