Countercurrent flow absorber and desorber

DOEpatents

Wilkinson, W.H.

1984-10-16

Countercurrent flow absorber and desorber devices are provided for use in absorption cycle refrigeration systems and thermal boosting systems. The devices have increased residence time and surface area resulting in improved heat and mass transfer characteristics. The apparatuses may be incorporated into open cycle thermal boosting systems in which steam serves both as the refrigerant vapor which is supplied to the absorber section and as the supply of heat to drive the desorber section of the system. 9 figs.

Use of Inert Gases and Carbon Monoxide to Study the Possible Influence of Countercurrent Exchange on Passive Absorption from the Small Bowel

PubMed Central

Bond, John H.; Levitt, David G.; Levitt, Michael D.

1974-01-01

The purpose of the present study was to quantitate the influence of countercurrent exchange on passive absorption of highly diffusible substances from the small intestine of the rabbit. The absorption of carbon monoxide, which is tightly bound to hemoglobin and therefore cannot exchange, was compared to the absorption of four unbound gases (H2, He, CH4, and 133Xe), which should exchange freely. The degree to which the observed absorption of the unbound gases falls below that predicted from CO absorption should provide a quantitative measure of countercurrent exchange. CO uptake at high luminal Pco is flow-limited and, assuming that villus and central hemoglobin concentrations are equal, the flow that equilibrates with CO (Fco) was calculated to equal 7.24 ml/min/100 g. The observed absorption rate of the unbound gases was from two to four times greater than would have been predicted had their entire uptake been accounted for by equilibration with Fco. This is the opposite of what would occur if countercurrent exchange retarded absorption of the unbound gases. The unbound gases have both flow- and diffusion-limited components, and Fco should account for only the fraction of absorption that is flow limited. A simple model of perfusion and diffusion made it possible to calculate the fraction of the total uptake of unbound gases that was flow limited. This fraction of the total observed absorption rate was still about 1.8 times greater than predicted by CO absorption. A possible explanation for this discrepancy is that plasma skimming reduces the hemoglobin of villus blood to about 60% of that of central blood. Thus, Fco is actually about 1.7 times greater than initially calculated, and with this correction, there is close agreement between the predicted and observed rates of absorption of each of the unbound gases. We conclude that countercurrent exchange does not influence passive absorption under the conditions of this study. PMID:4436431

Effects of dialysate flow configurations in continuous renal replacement therapy on solute removal: computational modeling.

PubMed

Kim, Jeong Chul; Cruz, Dinna; Garzotto, Francesco; Kaushik, Manish; Teixeria, Catarina; Baldwin, Marie; Baldwin, Ian; Nalesso, Federico; Kim, Ji Hyun; Kang, Eungtaek; Kim, Hee Chan; Ronco, Claudio

2013-01-01

Continuous renal replacement therapy (CRRT) is commonly used for critically ill patients with acute kidney injury. During treatment, a slow dialysate flow rate can be applied to enhance diffusive solute removal. However, due to the lack of the rationale of the dialysate flow configuration (countercurrent or concurrent to blood flow), in clinical practice, the connection settings of a hemodiafilter are done depending on nurse preference or at random. In this study, we investigated the effects of flow configurations in a hemodiafilter during continuous venovenous hemodialysis on solute removal and fluid transport using computational fluid dynamic modeling. We solved the momentum equation coupling solute transport to predict quantitative diffusion and convection phenomena in a simplified hemodiafilter model. Computational modeling results showed superior solute removal (clearance of urea: 67.8 vs. 45.1 ml/min) and convection (filtration volume: 29.0 vs. 25.7 ml/min) performances for the countercurrent flow configuration. Countercurrent flow configuration enhances convection and diffusion compared to concurrent flow configuration by increasing filtration volume and equilibrium concentration in the proximal part of a hemodiafilter and backfiltration of pure dialysate in the distal part. In clinical practice, the countercurrent dialysate flow configuration of a hemodiafilter could increase solute removal in CRRT. Nevertheless, while this configuration may become mandatory for high-efficiency treatments, the impact of differences in solute removal observed in slow continuous therapies may be less important. Under these circumstances, if continuous therapies are prescribed, some of the advantages of the concurrent configuration in terms of simpler circuit layout and simpler machine design may overcome the advantages in terms of solute clearance. Different dialysate flow configurations influence solute clearance and change major solute removal mechanisms in the proximal and distal parts of a hemodiafilter. Advantages of each configuration should be balanced against the overall performance of the treatment and its simplicity in terms of treatment delivery and circuit handling procedures. Copyright © 2013 S. Karger AG, Basel.

Experimental study of heat and mass transfer in a buoyant countercurrent exchange flow

NASA Astrophysics Data System (ADS)

Conover, Timothy Allan

Buoyant Countercurrent Exchange Flow occurs in a vertical vent through which two miscible fluids communicate, the higher-density fluid, residing above the lower-density fluid, separated by the vented partition. The buoyancy- driven zero net volumetric flow through the vent transports any passive scalars, such as heat and toxic fumes, between the two compartments as the fluids seek thermodynamic and gravitational equilibrium. The plume rising from the vent into the top compartment resembles a pool fire plume. In some circumstances both countercurrent flows and pool fires can ``puff'' periodically, with distinct frequencies. One experimental test section containing fresh water in the top compartment and brine (NaCl solution) in the bottom compartment provided a convenient, idealized flow for study. This brine flow decayed in time as the concentrations approached equilibrium. A second test section contained fresh water that was cooled by heat exchangers above and heated by electrical elements below and operated steadily, allowing more time for data acquisition. Brine transport was reduced to a buoyancy- scaled flow coefficient, Q*, and heat transfer was reduced to an analogous coefficient, H*. Results for vent diameter D = 5.08 cm were consistent between test sections and with the literature. Some results for D = 2.54 cm were inconsistent, suggesting viscosity and/or molecular diffusion of heat become important at smaller scales. Laser Doppler Velocimetry was used to measure velocity fields in both test sections, and in thermal flow a small thermocouple measured temperature simultaneously with velocity. Measurement fields were restricted to the plume base region, above the vent proper. In baseline periodic flow, instantaneous velocity and temperature were ensemble averaged, producing a movie of the average variation of each measure during a puffing flow cycle. The temperature movie revealed the previously unknown cold core of the puff during its early development. The renewal-length model for puffing frequency of pool fire plumes was extended to puffing countercurrent flows by estimating inflow dilution. Puffing frequencies at several conditions were reduced to Strouhal number based on dilute plume density. Results for D = 5.08 cm compared favorably to published measurements of puffing pool fires, suggesting that the two different flows obey the same periodic dynamic process.

Effect of gas-liquid flow pattern and microbial diversity analysis of a pilot-scale biotrickling filter for anoxic biogas desulfurization.

PubMed

Almenglo, Fernando; Bezerra, Tercia; Lafuente, Javier; Gabriel, David; Ramírez, Martín; Cantero, Domingo

2016-08-01

Hydrogen sulfide removal from biogas was studied under anoxic conditions in a pilot-scale biotrickling filter operated under counter- and co-current gas-liquid flow patterns. The best performance was found under counter-current conditions (maximum elimination capacity of 140 gS m(-3) h(-1)). Nevertheless, switching conditions between co- and counter-current flow lead to a favorable redistribution of biomass and elemental sulfur along the bed height. Moreover, elemental sulfur was oxidized to sulfate when the feeding biogas was disconnected and the supply of nitrate (electron acceptor) was maintained. Removal of elemental sulfur was important to prevent clogging in the packed bed and, thereby, to increase the lifespan of the packed bed between maintenance episodes. The larger elemental sulfur removal rate during shutdowns was 59.1 gS m(-3) h(-1). Tag-encoded FLX amplicon pyrosequencing was used to study the diversity of bacteria under co-current flow pattern with liquid recirculation and counter-current mode with a single-pass flow of the liquid phase. The main desulfurizing bacteria were Sedimenticola while significant role of heterotrophic, opportunistic species was envisaged. Remarkable differences between communities were found when a single-pass flow of industrial water was fed to the biotrickling filter. Copyright © 2016 Elsevier Ltd. All rights reserved.

The dispersal of the Amazon's water

NASA Technical Reports Server (NTRS)

Muller-Karger, Frank E.; Mcclain, Charles R.; Richardson, Philip L.

1988-01-01

New information obtained with NASA's Coastal Zone Color Scanner and with drifting buoys reveals that the discharge of the Amazon is carried offshore around a retroflection of the North Brazil Current and into the North Equatorial Countercurrent towards Africa between June and January each year. From about February to May, the countercurrent and the retroflection weaken or vanish, and Amazon water flows northwestward toward the Caribbean Sea.

Countercurrent flow of supercritical anti-solvent in the production of pure xanthophylls from Nannochloropsis oculata.

PubMed

Cho, Yueh-Cheng; Wang, Yuan-Chuen; Shieh, Chwen-Jen; Lin, Justin Chun-Te; Chang, Chieh-Ming J; Han, Esther

2012-08-10

This study examined pilot scaled elution chromatography coupled with supercritical anti-solvent precipitation (using countercurrent flow) in generating zeaxanthin-rich particulates from a micro-algal species. Ultrasonic agitated acetone extract subjected to column fractionation successfully yielded a fraction containing 349.4 mg/g of zeaxanthin with a recovery of 85%. Subsequently, supercritical anti-solvent (SAS) precipitation of the column fraction at 150 bar and 343 K produced submicron-sized particulates with a concentration of 845.5mg/g of zeaxanthin with a recovery of 90%. Experimental results from a two-factor response surface method SAS precipitation indicated that purity, mean size and morphology of the precipitates were significantly affected by the flow type configuration, feed flow rate and injection time. Copyright © 2012 Elsevier B.V. All rights reserved.

An easy-to-use calculating machine to simulate steady state and non-steady-state preparative separations by multiple dual mode counter-current chromatography with semi-continuous loading of feed mixtures.

PubMed

Kostanyan, Artak E; Shishilov, Oleg N

2018-06-01

Multiple dual mode counter-current chromatography (MDM CCC) separation processes with semi-continuous large sample loading consist of a succession of two counter-current steps: with "x" phase (first step) and "y" phase (second step) flow periods. A feed mixture dissolved in the "x" phase is continuously loaded into a CCC machine at the beginning of the first step of each cycle over a constant time with the volumetric rate equal to the flow rate of the pure "x" phase. An easy-to-use calculating machine is developed to simulate the chromatograms and the amounts of solutes eluted with the phases at each cycle for steady-state (the duration of the flow periods of the phases is kept constant for all the cycles) and non-steady-state (with variable duration of alternating phase elution steps) separations. Using the calculating machine, the separation of mixtures containing up to five components can be simulated and designed. Examples of the application of the calculating machine for the simulation of MDM CCC processes are discussed. Copyright © 2018 Elsevier B.V. All rights reserved.

Validation of theoretical models of intrinsic torque in DIII-D

NASA Astrophysics Data System (ADS)

Grierson, B. A.; Wang, W. X.; Battaglia, D. J.; Chrystal, C.; Solomon, W. M.; Degrassie, J. S.; Staebler, G. M.; Boedo, J. A.

2016-10-01

Plasma rotation experiments in DIII-D are validating models of main-ion intrinsic rotation by testing Reynolds stress induced toroidal flow in the plasma core and intrinsic rotation induced by ion orbit losses in the plasma edge. In the core of dominantly electron heated plasmas with Te=Ti, the main-ion intrinsic toroidal rotation undergoes a reversal that correlates with the critical gradient for ITG turbulence. Residual stress arising from zonal-flow ExB shear and turbulence intensity gradient produce residual stress and counter-current intrinsic torque, which is balanced by momentum diffusion, creating the hollow profile. Quantitative agreement is obtained for the first time between the measured main-ion toroidal rotation and the rotation profile predicted by nonlinear GTS gyrokinetic simulations. At the plasma boundary, new main-ion CER measurements show a co-current rotation layer and this is tested against ion orbit loss models as the source of bulk plasma rotation. Work supported by the US Department of Energy under DE-AC02-09CH11466 and DE-FC02-04ER54698.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Stoltzfus-Dueck, T.; Scott, B.

An often-neglected portion of the radialmore » $$\\boldsymbol{E}\\times \\boldsymbol{B}$$ drift is shown to drive an outward flux of co-current momentum when free energy is transferred from the electrostatic potential to ion parallel flows. This symmetry breaking is fully nonlinear, not quasilinear, necessitated simply by free-energy balance in parameter regimes for which significant energy is dissipated via ion parallel flows. The resulting rotation peaking is counter-current and has a scaling and order of magnitude that are comparable with experimental observations. Finally, the residual stress becomes inactive when frequencies are much higher than the ion transit frequency, which may explain the observed relation of density peaking and counter-current rotation peaking in the core.« less

Liquid cooled counter flow turbine bucket

DOEpatents

Dakin, James T.

1982-09-21

Means and a method are provided whereby liquid coolant flows radially outward through coolant passages in a liquid cooled turbine bucket under the influence of centrifugal force while in contact with countercurrently flowing coolant vapor such that liquid is entrained in the flow of vapor resulting in an increase in the wetted cooling area of the individual passages.

Hybrid upwind discretization of nonlinear two-phase flow with gravity

NASA Astrophysics Data System (ADS)

Lee, S. H.; Efendiev, Y.; Tchelepi, H. A.

2015-08-01

Multiphase flow in porous media is described by coupled nonlinear mass conservation laws. For immiscible Darcy flow of multiple fluid phases, whereby capillary effects are negligible, the transport equations in the presence of viscous and buoyancy forces are highly nonlinear and hyperbolic. Numerical simulation of multiphase flow processes in heterogeneous formations requires the development of discretization and solution schemes that are able to handle the complex nonlinear dynamics, especially of the saturation evolution, in a reliable and computationally efficient manner. In reservoir simulation practice, single-point upwinding of the flux across an interface between two control volumes (cells) is performed for each fluid phase, whereby the upstream direction is based on the gradient of the phase-potential (pressure plus gravity head). This upwinding scheme, which we refer to as Phase-Potential Upwinding (PPU), is combined with implicit (backward-Euler) time discretization to obtain a Fully Implicit Method (FIM). Even though FIM suffers from numerical dispersion effects, it is widely used in practice. This is because of its unconditional stability and because it yields conservative, monotone numerical solutions. However, FIM is not unconditionally convergent. The convergence difficulties are particularly pronounced when the different immiscible fluid phases switch between co-current and counter-current states as a function of time, or (Newton) iteration. Whether the multiphase flow across an interface (between two control-volumes) is co-current, or counter-current, depends on the local balance between the viscous and buoyancy forces, and how the balance evolves in time. The sensitivity of PPU to small changes in the (local) pressure distribution exacerbates the problem. The common strategy to deal with these difficulties is to cut the timestep and try again. Here, we propose a Hybrid-Upwinding (HU) scheme for the phase fluxes, then HU is combined with implicit time discretization to yield a fully implicit method. In the HU scheme, the phase flux is divided into two parts based on the driving force. The viscous-driven and buoyancy-driven phase fluxes are upwinded differently. Specifically, the viscous flux, which is always co-current, is upwinded based on the direction of the total-velocity. The buoyancy-driven flux across an interface is always counter-current and is upwinded such that the heavier fluid goes downward and the lighter fluid goes upward. We analyze the properties of the Implicit Hybrid Upwinding (IHU) scheme. It is shown that IHU is locally conservative and produces monotone, physically-consistent numerical solutions. The IHU solutions show numerical diffusion levels that are slightly higher than those for standard FIM (i.e., implicit PPU). The primary advantage of the IHU scheme is that the numerical overall-flux of a fluid phase remains continuous and differentiable as the flow regime changes between co-current and counter-current conditions. This is in contrast to the standard phase-potential upwinding scheme, in which the overall fractional-flow (flux) function is non-differentiable across the boundary between co-current and counter-current flows.

Momentum flux parasitic to free-energy transfer

DOE PAGES

Stoltzfus-Dueck, T.; Scott, B.

2017-05-11

An often-neglected portion of the radialmore » $$\\boldsymbol{E}\\times \\boldsymbol{B}$$ drift is shown to drive an outward flux of co-current momentum when free energy is transferred from the electrostatic potential to ion parallel flows. This symmetry breaking is fully nonlinear, not quasilinear, necessitated simply by free-energy balance in parameter regimes for which significant energy is dissipated via ion parallel flows. The resulting rotation peaking is counter-current and has a scaling and order of magnitude that are comparable with experimental observations. Finally, the residual stress becomes inactive when frequencies are much higher than the ion transit frequency, which may explain the observed relation of density peaking and counter-current rotation peaking in the core.« less

Electric field-driven, magnetically-stabilized ferro-emulsion phase contactor

DOEpatents

Scott, T.C.

1990-07-17

Methods and systems are disclosed for interfacial surface area contact between a dispersed phase liquid and a continuous phase liquid in counter-current flow for purposes such as solvent extraction. Initial droplets of a dispersed phase liquid material containing ferromagnetic particles functioning as a packing'' are introduced to a counter-current flow of the continuous phase. A high intensity pulsed electric field is applied so as to shatter the initial droplets into a ferromagnetic emulsion comprising many smaller daughter droplets having a greater combined total surface area than that of the initial droplets in contact with the continuous phase material. A magnetic field is applied to control the position of the ferromagnetic emulsion for enhanced coalescence of the daughter droplets into larger reformed droplets. 2 figs.

Electric field-driven, magnetically-stabilized ferro-emulsion phase contactor

DOEpatents

Scott, Timothy C.

1990-01-01

Methods and systems for interfacial surface area contact between a dispersed phase liquid and a continuous phase liquid in counter-current flow for purposes such as solvent extraction. Initial droplets of a dispersed phase liquid material containing ferromagnetic particles functioning as a "packing" are introduced to a counter-current flow of the continuous phase. A high intensity pulsed electric field is applied so as to shatter the initial droplets into a ferromagnetic emulsion comprising many smaller daughter droplets having a greater combined total surface area than that of the initial droplets in contact with the continuous phase material. A magnetic field is applied to control the position of the ferromagnetic emulsion for enhanced coalescence of the daughter droplets into larger reformed droplets.

Experimental investigation of heat transfer characteristics of guar-based polymer solutions and gels

DOE Office of Scientific and Technical Information (OSTI.GOV)

Azouz, I.; Vinod, P.S.; Shah, S.N.

1996-12-31

An experimental investigation of the heat transfer characteristics of hydraulic fracturing fluids was conducted at the Fracturing Fluid Characterization Facility (FFCF) of the University of Oklahoma. The facility is equipped with a high pressure fracture simulator, coiled tubing fluid pre-conditioning system, and a full-scale, counter-current, double pipe heat exchanger. The fluids investigated include non-crosslinked and borate-crosslinked guar gum and hydroxypropyl guar (HPG). Results were also obtained for water and were used as a basis for comparison. The effects of flow rate, operating temperature, pH, and various levels of shear pre-conditioning, on the heat transfer behavior of the test fluids weremore » investigated. Results show a significant difference between the heat transfer coefficient of the pure solvent (water) and those of the polymer solutions tested. While all polymer solutions tested exhibited lower heat transfer coefficients than that of the pure solvent, crosslinking appears to enhance the heat transfer characteristics of the polymer fluids. It was also observed that shear preconditioning does not seem to have a significant effect on the heat transfer coefficient of the crosslinked gels. These findings are of great interest to the industry, especially to the petroleum industry where these fluids are commonly used during hydraulic fracturing of hydrocarbon reservoirs.« less

Countercurrent flow afterburner

DOEpatents

Leggett, Ronald L.; Presse, Donald E.; Smith, Carl J.; Teter, Alton R.

1976-01-01

Afterburner apparatus for receiving from an incinerator products of combustion and distributing them through a domed distributor in counterflow manner throughout a housing, in opposition to a stream of combustible gas.

Countercurrent heat exchange and thermoregulation during blood-feeding in kissing bugs

PubMed Central

Lahondère, Chloé; Insausti, Teresita C; Belev, George; Pereira, Marcos H

2017-01-01

Blood-sucking insects experience thermal stress at each feeding event on endothermic vertebrates. We used thermography to examine how kissing-bugs Rhodnius prolixus actively protect themselves from overheating. During feeding, these bugs sequester and dissipate the excess heat in their heads while maintaining an abdominal temperature close to ambient. We employed a functional-morphological approach, combining histology, µCT and X-ray-synchrotron imaging to shed light on the way these insects manage the flow of heat across their bodies. The close alignment of the circulatory and ingestion systems, as well as other morphological characteristics, support the existence of a countercurrent heat exchanger in the head of R. prolixus, which decreases the temperature of the ingested blood before it reaches the abdomen. This kind of system has never been described before in the head of an insect. For the first time, we show that countercurrent heat exchange is associated to thermoregulation during blood-feeding. PMID:29157359

METHOD OF CENTRIFUGE OPERATION

DOEpatents

Cohen, K.

1960-05-10

A method of isotope separation is described in which two streams are flowed axially of, and countercurrently through, a cylindrical centrifuge bowl. Under the influence of a centrifugal field, the light fraction is concentrated in a stream flowing through the central portion of the bowl, whereas the heavy fraction is concentrated in a stream at the periphery thereof.

Countercurrent flow limited (CCFL) heat flux in the high flux isotope reactor (HFIR) fuel element

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ruggles, A.E.

1990-10-12

The countercurrent flow (CCF) performance in the fuel element region of the HFIR is examined experimentally and theoretically. The fuel element consists of two concentric annuli filled with aluminum clad fuel plates of 1.27 mm thickness separated by 1.27 mm flow channels. The plates are curved as they go radially outward to accomplish constant flow channel width and constant metal-to-coolant ratio. A full-scale HFIR fuel element mock-up is studied in an adiabatic air-water CCF experiment. A review of CCF models for narrow channels is presented along with the treatment of CCFs in system of parallel channels. The experimental results aremore » related to the existing models and a mechanistic model for the annular'' CCF in a narrow channel is developed that captures the data trends well. The results of the experiment are used to calculate the CCFL heat flux of the HFIR fuel assembly. It was determined that the HFIR fuel assembly can reject 0.62 Mw of thermal power in the CCFL situation. 31 refs., 17 figs.« less

Gas holdup and flow regime transition in spider-sparger bubble column: effect of liquid phase properties

NASA Astrophysics Data System (ADS)

Besagni, G.; Inzoli, F.; De Guido, G.; Pellegrini, L. A.

2017-01-01

This paper discusses the effects of the liquid velocity and the liquid phase properties on the gas holdup and the flow regime transition in a large-diameter and large-scale counter-current two-phase bubble column. In particular, we compared and analysed the experimental data obtained in our previous experimental studies. The bubble column is 5.3 m in height, has an inner diameter of 0.24 m, it was operated with gas superficial velocities in the range of 0.004-0.20 m/s and, in the counter-current mode, the liquid was recirculated up to a superficial velocity of -0.09 m/s. Air was used as the dispersed phase and various fluids (tap water, aqueous solutions of sodium chloride, ethanol and monoethylene glycol) were employed as liquid phases. The experimental dataset consist in gas holdup measurements and was used to investigate the global fluid dynamics and the flow regime transition between the homogeneous flow regime and the transition flow regime. We found that the liquid velocity and the liquid phase properties significantly affect the gas holdup and the flow regime transition. In this respect, a possible relationship (based on the lift force) between the flow regime transition and the gas holdup was proposed.

Circulation Plasma Centrifuge with Product Flow

NASA Astrophysics Data System (ADS)

Borisevich, V. D.; Potanin, E. P.

2018-05-01

We have analyzed the isotope separation in a high-frequency plasma circulating centrifuge operating with a product flow. The rotation of a weakly ionized plasma is ensured by a rotating magnetic field, while the countercurrent flow (circulation) is produced by a traveling magnetic field. We have calculated the dependences of the enrichment factor and the separative power of the centrifuge on a product flow. The optimal characteristics of the separation unit have been determined.

Improved separation with the intermittently pressed tubing of multilayer coil in type-I counter-current chromatography.

PubMed

Yang, Yi; Yang, Jiao; Fang, Chen; Wang, Jihui; Gu, Dongyu; Tian, Jing; Ito, Yoichiro

2018-05-25

The intermittently pressed tubing was introduced in type-I counter-current chromatographic system as the separation column to improve the separation performance in the present study. The separations were performed with two different solvent systems composed of 1-butanol-acetic acid-water (4:1:5, v/v) (BAW) and hexane-ethyl acetate-methanol-0.1 M HCl (1:1:1:1, v/v) (HEMW) using dipeptides and DNP-amino acids as test samples, respectively. The chromatographic performance was evaluated in terms of retention of the stationary phase (Sf), theoretical plate (N) and peak resolution (Rs). In general, the type-I planetary motion with the multilayer coil of non-modified standard tubing can yield the best separation at a low revolution speed of 200 rpm with lower flow rate. The present results with intermittently pressed tubing indicated that the performance was also optimal at the revolution speed of 200 rpm where the lower flow rate was more beneficial to retention of stationary phase and resolution. In the moderately hydrophobic two-phase solvent system composed of hexane-ethyl acetate-metanol-0.1 M hydrochloric acid (1:1:1:1, v/v), DNP-amino acids were separated with Rs at 1.67 and 1.47, respectively, with 12.66% of stationary phase retention at a flow rate of 0.25 ml/min. In the polar solvent system composed of 1-butanol-acetic acid-water (4:1:5, v/v), dipeptide samples were resolved with Rs at 2.18 and 18.75% of stationary phase retention at a flow rate of 0.25 ml/min. These results indicate that the present system substantially improves the separation efficiency of type-I counter-current chromatographic system. Published by Elsevier B.V.

A simple tool for tubing modification to improve spiral high-speed counter-current chromatography for protein purification

PubMed Central

Ito, Yoichiro; Ma, Xiaofeng; Clary, Robert

2016-01-01

A simple tool is introduced which can modify the shape of tubing to enhance the partition efficiency in high-speed countercurrent chromatography. It consists of a pair of interlocking identical gears, each coaxially holding a pressing wheel to intermittently compress plastic tubing in 0 – 10 mm length at every 1 cm interval. The performance of the processed tubing is examined in protein separation with 1.6 mm ID PTFE tubing intermittently pressed in 3 mm and 10 mm width both at 10 mm intervals at various flow rates and revolution speeds. A series of experiments was performed with a polymer phase system composed of polyethylene glycol and dibasic potassium phosphate each at 12.5% (w/w) in deionized water using three protein samples. Overall results clearly demonstrate that the compressed tubing can yield substantially higher peak resolution than the non-processed tubing. The simple tubing modifier is very useful for separation of proteins with high-speed countercurrent chromatography. PMID:27818942

A simple tool for tubing modification to improve spiral high-speed counter-current chromatography for protein purification.

PubMed

Ito, Yoichiro; Ma, Xiaofeng; Clary, Robert

2016-01-01

A simple tool is introduced which can modify the shape of tubing to enhance the partition efficiency in high-speed countercurrent chromatography. It consists of a pair of interlocking identical gears, each coaxially holding a pressing wheel to intermittently compress plastic tubing in 0 - 10 mm length at every 1 cm interval. The performance of the processed tubing is examined in protein separation with 1.6 mm ID PTFE tubing intermittently pressed in 3 mm and 10 mm width both at 10 mm intervals at various flow rates and revolution speeds. A series of experiments was performed with a polymer phase system composed of polyethylene glycol and dibasic potassium phosphate each at 12.5% (w/w) in deionized water using three protein samples. Overall results clearly demonstrate that the compressed tubing can yield substantially higher peak resolution than the non-processed tubing. The simple tubing modifier is very useful for separation of proteins with high-speed countercurrent chromatography.

Hydrodynamics of a Multistage Wet Scrubber Incineration Conditions

ERIC Educational Resources Information Center

Said, M. M.; Manyele, S. V.; Raphael, M. L.

2012-01-01

The objective of the study was to determine the hydrodynamics of the two stage counter-current cascade wet scrubbers used during incineration of medical waste. The dependence of the hydrodynamics on two main variables was studied: Inlet air flow rate and inlet liquid flow rate. This study introduces a new wet scrubber operating features, which are…

Counter-current motion in counter-current chromatography.

PubMed

Ito, Yoichiro

2014-12-12

After the CCC2012 meeting, I have received an e-mail regarding the terminology of "Countercurrent Chromatography". It stated that the term "Countercurrent" is a misnomer, because its stationary phase is motionless in the column and that the method should be renamed as liquid-liquid separations or centrifugal separations. However, it was found that these names are already used for various other techniques as found via Google search. The term "Countercurrent Chromatography" was originally made after two preparative methods of Countercurrent distribution and liquid Chromatography, both having no countercurrent motion in the column. However, it is surprising to find that this F1 hybrid method "Countercurrent Chromatography" can clearly exhibit countercurrent motion within the separation column in both hydrodynamic and hydrostatic equilibrium systems. This justifies that "Countercurrent Chromatography" is a proper term for this chromatographic method. Published by Elsevier B.V.

Wall pressure measurements of flooding in vertical countercurrent annular air–water flow

DOE Office of Scientific and Technical Information (OSTI.GOV)

Choutapalli, I., Vierow, K.

2010-01-01

An experimental study of flooding in countercurrent air-water annular flow in a large diameter vertical tube using wall pressure measurements is described in this paper. Axial pressure profiles along the length of the test section were measured up to and after flooding using fast response pressure transducers for three representative liquid flow rates representing a wide range of liquid Reynolds numbers (ReL = 4Γ/μ; Γ is the liquid mass flow rate per unit perimeter; μ is the dynamic viscosity) from 3341 to 19,048. The results show that flooding in large diameter tubes cannot be initiated near the air outlet andmore » is only initiated near the air inlet. Fourier analysis of the wall pressure measurements shows that up to the point of flooding, there is no dominant wave frequency but rather a band of frequencies encompassing both the low frequency and the broad band that are responsible for flooding. The data indicates that flooding in large diameter vertical tubes may be caused by the constructive superposition of a plurality of waves rather than the action of a single large-amplitude wave.« less

Analytical Study on Thermal and Mechanical Design of Printed Circuit Heat Exchanger

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yoon, Su-Jong; Sabharwall, Piyush; Kim, Eung-Soo

2013-09-01

The analytical methodologies for the thermal design, mechanical design and cost estimation of printed circuit heat exchanger are presented in this study. In this study, three flow arrangements of parallel flow, countercurrent flow and crossflow are taken into account. For each flow arrangement, the analytical solution of temperature profile of heat exchanger is introduced. The size and cost of printed circuit heat exchangers for advanced small modular reactors, which employ various coolants such as sodium, molten salts, helium, and water, are also presented.

Separation of phenolic acids from sugarcane rind by online solid-phase extraction with high-speed counter-current chromatography.

PubMed

Geng, Ping; Fang, Yingtong; Xie, Ronglong; Hu, Weilun; Xi, Xingjun; Chu, Qiao; Dong, Genlai; Shaheen, Nusrat; Wei, Yun

2017-02-01

Sugarcane rind contains some functional phenolic acids. The separation of these compounds from sugarcane rind is able to realize the integrated utilization of the crop and reduce environment pollution. In this paper, a novel protocol based on interfacing online solid-phase extraction with high-speed counter-current chromatography (HSCCC) was established, aiming at improving and simplifying the process of phenolic acids separation from sugarcane rind. The conditions of online solid-phase extraction with HSCCC involving solvent system, flow rate of mobile phase as well as saturated extent of absorption of solid-phase extraction were optimized to improve extraction efficiency and reduce separation time. The separation of phenolic acids was performed with a two-phase solvent system composed of butanol/acetic acid/water at a volume ratio of 4:1:5, and the developed online solid-phase extraction with HSCCC method was validated and successfully applied for sugarcane rind, and three phenolic acids including 6.73 mg of gallic acid, 10.85 mg of p-coumaric acid, and 2.78 mg of ferulic acid with purities of 60.2, 95.4, and 84%, respectively, were obtained from 150 mg sugarcane rind crude extracts. In addition, the three different elution methods of phenolic acids purification including HSCCC, elution-extrusion counter-current chromatography and back-extrusion counter-current chromatography were compared. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Counter-current thermocapillary migration of bubbles in self-rewetting liquids

NASA Astrophysics Data System (ADS)

Nazareth, R.; Saenz, P.; Sefiane, K.; Kim, J.; Valluri, P.

2016-11-01

In this work, we study the counter-current thermocapillary propulsion of a suspended bubble in the fluid flowing inside a channel subject to an axial temperature gradient when the surface tension dependence on temperature is non-monotonic. We use direct numerical simulations to address the two-phase conservation of mass, momentum and energy with a volume-of-fluid method to resolve the deformable interface. Two distinct regimes of counter-current bubble migration are characterized: i) "exponential decay" where the bubble decelerates rapidly until it comes to a halt at the spatial position corresponding to the minimum surface tension and ii) "sustained oscillations" where the bubble oscillates about the point of minimum surface tension. We illustrate how these sustained oscillations arise at low capillary number O(10-5) and moderate Reynolds number O(10) and, they are dampened by viscosity at lower Reynolds number. These results are in agreement with the experiments by Shanahan and Sefiane (Sci. Rep. 4, 2014). The work was supported by the Science without Borders program from CAPES agency of Brazilian Ministry of Education and the European Commission's Thermapower Project (294905).

Schinus terebinthifolius countercurrent chromatography (Part III): Method transfer from small countercurrent chromatography column to preparative centrifugal partition chromatography ones as a part of method development.

PubMed

das Neves Costa, Fernanda; Hubert, Jane; Borie, Nicolas; Kotland, Alexis; Hewitson, Peter; Ignatova, Svetlana; Renault, Jean-Hugues

2017-03-03

Countercurrent chromatography (CCC) and centrifugal partition chromatography (CPC) are support free liquid-liquid chromatography techniques sharing the same basic principles and features. Method transfer has previously been demonstrated for both techniques but never from one to another. This study aimed to show such a feasibility using fractionation of Schinus terebinthifolius berries dichloromethane extract as a case study. Heptane - ethyl acetate - methanol -water (6:1:6:1, v/v/v/v) was used as solvent system with masticadienonic and 3β-masticadienolic acids as target compounds. The optimized separation methodology previously described in Part I and II, was scaled up from an analytical hydrodynamic CCC column (17.4mL) to preparative hydrostatic CPC instruments (250mL and 303mL) as a part of method development. Flow-rate and sample loading were further optimized on CPC. Mobile phase linear velocity is suggested as a transfer invariant parameter if the CPC column contains sufficient number of partition cells. Copyright © 2017 Elsevier B.V. All rights reserved.

Gas-liquid countercurrent integration process for continuous biodiesel production using a microporous solid base KF/CaO as catalyst.

PubMed

Hu, Shengyang; Wen, Libai; Wang, Yun; Zheng, Xinsheng; Han, Heyou

2012-11-01

A continuous-flow integration process was developed for biodiesel production using rapeseed oil as feedstock, based on the countercurrent contact reaction between gas and liquid, separation of glycerol on-line and cyclic utilization of methanol. Orthogonal experimental design and response surface methodology were adopted to optimize technological parameters. A second-order polynomial model for the biodiesel yield was established and validated experimentally. The high determination coefficient (R(2)=98.98%) and the low probability value (Pr<0.0001) proved that the model matched the experimental data, and had a high predictive ability. The optimal technological parameters were: 81.5°C reaction temperature, 51.7cm fill height of catalyst KF/CaO and 105.98kPa system pressure. Under these conditions, the average yield of triplicate experiments was 93.7%, indicating the continuous-flow process has good potential in the manufacture of biodiesel. Copyright © 2012 Elsevier Ltd. All rights reserved.

Opposed slant tube diabatic sorber

DOEpatents

Erickson, Donald C.

2004-01-20

A sorber comprised of at least three concentric coils of tubing contained in a shell with a flow path for liquid sorbent in one direction, a flow path for heat transfer fluid which is in counter-current heat exchange relationship with sorbent flow, a sorbate vapor port in communication with at least one of sorbent inlet or exit ports, wherein each coil is coiled in opposite direction to those coils adjoining it, whereby the opposed slant tube configuration is achieved, with structure for flow modification in the core space inside the innermost coil.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ermanoski, Ivan; Orozco, Adrian

In this report we present the development of a packed particle bed recirculator and heat exchanger. The device is intended to create countercurrent flows of packed particle beds and exchange heat between the flows. The project focused on the design, fabrication, demonstration, and modifications of a simple prototype, in order to attain high levels of heat exchange between particle flows while maintaining an effective particle conveying rate in a scalable package. Despite heat losses in a package not optimized for heat retention, 50% heat recovery was achieved, at a particle conveying efficiency of 40%.

Comparison in partition efficiency of protein separation between four different tubing modifications in spiral high-speed countercurrent chromatography

PubMed Central

Ito, Yoichiro; Clary, Robert

2016-01-01

High-speed countercurrent chromatography with a spiral tube assembly can retain a satisfactory amount of stationary phase of polymer phase systems used for protein separation. In order to improve the partition efficiency a simple tool to modify the tubing shapes was fabricated, and the following four different tubing modifications were made: intermittently pressed at 10 mm width, flat, flat-wave, and flat-twist. Partition efficiencies of the separation column made from these modified tubing were examined in protein separation with an aqueous-aqueous polymer phase system at flow rates of 1–2 ml/min under 800 rpm. The results indicated that the column with all modified tubing improved the partition efficiency at a flow rate of 1 ml/min, but at a higher flow rate of 2 ml/min the columns made of flattened tubing showed lowered partition efficiency apparently due to the loss of the retained stationary phase. Among all the modified columns, the column with intermittently pressed tubing gave the best peak resolution. It may be concluded that the intermittently pressed and flat-twist improve the partition efficiency in a semi-preparative separation while other modified tubing of flat and flat-wave configurations may be used for analytical separations with a low flow rate. PMID:27790621

Comparison in partition efficiency of protein separation between four different tubing modifications in spiral high-speed countercurrent chromatography.

PubMed

Ito, Yoichiro; Clary, Robert

2016-12-01

High-speed countercurrent chromatography with a spiral tube assembly can retain a satisfactory amount of stationary phase of polymer phase systems used for protein separation. In order to improve the partition efficiency a simple tool to modify the tubing shapes was fabricated, and the following four different tubing modifications were made: intermittently pressed at 10 mm width, flat, flat-wave, and flat-twist. Partition efficiencies of the separation column made from these modified tubing were examined in protein separation with an aqueous-aqueous polymer phase system at flow rates of 1-2 ml/min under 800 rpm. The results indicated that the column with all modified tubing improved the partition efficiency at a flow rate of 1 ml/min, but at a higher flow rate of 2 ml/min the columns made of flattened tubing showed lowered partition efficiency apparently due to the loss of the retained stationary phase. Among all the modified columns, the column with intermittently pressed tubing gave the best peak resolution. It may be concluded that the intermittently pressed and flat-twist improve the partition efficiency in a semi-preparative separation while other modified tubing of flat and flat-wave configurations may be used for analytical separations with a low flow rate.

MICROBIAL COMETABOLISM OF RECALCITRANT CHEMICALS IN CONTAMINATED AIR STREAMS

EPA Science Inventory

Chlorinated Solvents: The treatment system consists of a laboratory-scale hollow fiber membrane (HFM) module containing a center baffle and a radial cross-flow pattern on the shell side of the fibers. The shell and lumen fluids are contacting in a counter-current f...

How shear increments affect the flow production branching ratio in CSDX

NASA Astrophysics Data System (ADS)

Li, J. C.; Diamond, P. H.

2018-06-01

The coupling of turbulence-driven azimuthal and axial flows in a linear device absent magnetic shear (Controlled Shear Decorrelation Experiment) is investigated. In particular, we examine the apportionment of Reynolds power between azimuthal and axial flows, and how the azimuthal flow shear affects axial flow generation and saturation by drift wave turbulence. We study the response of the energy branching ratio, i.e., ratio of axial and azimuthal Reynolds powers, PzR/PyR , to incremental changes of azimuthal and axial flow shears. We show that increasing azimuthal flow shear decreases the energy branching ratio. When axial flow shear increases, this ratio first increases but then decreases to zero. The axial flow shear saturates below the threshold for parallel shear flow instability. The effects of azimuthal flow shear on the generation and saturation of intrinsic axial flows are analyzed. Azimuthal flow shear slows down the modulational growth of the seed axial flow shear, and thus reduces intrinsic axial flow production. Azimuthal flow shear reduces both the residual Reynolds stress (of axial flow, i.e., ΠxzR e s ) and turbulent viscosity ( χzDW ) by the same factor |⟨vy⟩'|-2Δx-2Ln-2ρs2cs2 , where Δx is the distance relative to the reference point where ⟨vy⟩=0 in the plasma frame. Therefore, the stationary state axial flow shear is not affected by azimuthal flow shear to leading order since ⟨vz⟩'˜ΠxzR e s/χzDW .

Coastal counter-currents setup patterns in the Gulf of Cadiz

NASA Astrophysics Data System (ADS)

Relvas, P.; Juniór, L.; Garel, E.; Drago, T.

2017-12-01

Alongshore coastal counter-currents (CCC) are frequent features of Eastern Boundary Upwelling Systems, where they temporally alternate with upwelling driven jets of opposite direction. Along the northern margin of the Gulf of Cadiz inner shelf, these CCCs are oriented poleward (eastward) and responsible for sharp temperature increases during the upwelling season, along with potential decline in water quality at the coast. This research is based on a multi-year ADCP velocity time-series (2008-2017), recorded at a single location (23 m water depth) over 13 deployments up to 3 months-long. The analysis focuses on the water column alongshore velocities during current inversions (i.e., the transition from equatorward upwelling jets to poleward CCCs). A set of parameters were derived from the flow structure to identify distinct types of inversions and to hypothesize about their driving mechanisms. Results show that 77% of the inversions start near the bed, propagating then to the upper layers. The bottom layer also changes direction before the surface layer for most events (71%). The vertical shear in this case is one order of magnitude greater than in the (less frequent) opposite situation. No seasonal variability is observed in the CCC occurrences. However, the parameters analysed in this study suggest different types of inversion between winter and summer. In winter, inversions are well defined (low variability), with similar patterns near the surface and bed layers as a result of a strong barotropic component. In summer the inversion patterns are more variable. In particular, the upper and bed layers are often importantly decoupled during inversions, indicating the strengthening of baroclinicity. A categorization of inversions events is proposed based on cross-correlation and multi-variable analyses of the developed parameters. Various types of inversion are obtained, suggesting that CCCs are driven by different forcings that may act separately or jointly.

Time-dependent rheological behavior of natural polysaccharide xanthan gum solutions in interrupted shear and step-incremental/reductional shear flow fields

NASA Astrophysics Data System (ADS)

Lee, Ji-Seok; Song, Ki-Won

2015-11-01

The objective of the present study is to systematically elucidate the time-dependent rheological behavior of concentrated xanthan gum systems in complicated step-shear flow fields. Using a strain-controlled rheometer (ARES), step-shear flow behaviors of a concentrated xanthan gum model solution have been experimentally investigated in interrupted shear flow fields with a various combination of different shear rates, shearing times and rest times, and step-incremental and step-reductional shear flow fields with various shearing times. The main findings obtained from this study are summarized as follows. (i) In interrupted shear flow fields, the shear stress is sharply increased until reaching the maximum stress at an initial stage of shearing times, and then a stress decay towards a steady state is observed as the shearing time is increased in both start-up shear flow fields. The shear stress is suddenly decreased immediately after the imposed shear rate is stopped, and then slowly decayed during the period of a rest time. (ii) As an increase in rest time, the difference in the maximum stress values between the two start-up shear flow fields is decreased whereas the shearing time exerts a slight influence on this behavior. (iii) In step-incremental shear flow fields, after passing through the maximum stress, structural destruction causes a stress decay behavior towards a steady state as an increase in shearing time in each step shear flow region. The time needed to reach the maximum stress value is shortened as an increase in step-increased shear rate. (iv) In step-reductional shear flow fields, after passing through the minimum stress, structural recovery induces a stress growth behavior towards an equilibrium state as an increase in shearing time in each step shear flow region. The time needed to reach the minimum stress value is lengthened as a decrease in step-decreased shear rate.

Method for enhancing selectivity and recovery in the fractional flotation of particles in a flotation column

DOEpatents

Klunder, Edgar B [Bethel Park, PA

2011-08-09

The method relates to particle separation from a feed stream. The feed stream is injected directly into the froth zone of a vertical flotation column in the presence of a counter-current reflux stream. A froth breaker generates a reflux stream and a concentrate stream, and the reflux stream is injected into the froth zone to mix with the interstitial liquid between bubbles in the froth zone. Counter-current flow between the plurality of bubbles and the interstitial liquid facilitates the attachment of higher hydrophobicity particles to bubble surfaces as lower hydrophobicity particles detach. The height of the feed stream injection and the reflux ratio may be varied in order to optimize the concentrate or tailing stream recoveries desired based on existing operating conditions.

Platelets Drive Thrombus Propagation in a Hematocrit and Glycoprotein VI-Dependent Manner in an In Vitro Venous Thrombosis Model.

PubMed

Lehmann, Marcus; Schoeman, Rogier M; Krohl, Patrick J; Wallbank, Alison M; Samaniuk, Joseph R; Jandrot-Perrus, Martine; Neeves, Keith B

2018-05-01

The objective of this study was to measure the role of platelets and red blood cells on thrombus propagation in an in vitro model of venous valvular stasis. A microfluidic model with dimensional similarity to human venous valves consists of a sinus distal to a sudden expansion, where for sufficiently high Reynolds numbers, 2 countercurrent vortices arise because of flow separation. The primary vortex is defined by the points of flow separation and reattachment. A secondary vortex forms in the deepest recess of the valve pocket characterized by low shear rates. An initial fibrin gel formed within the secondary vortex of a tissue factor-coated valve sinus. Platelets accumulated at the interface of the fibrin gel and the primary vortex. Red blood cells at physiological hematocrits were necessary to provide an adequate flux of platelets to support thrombus growth out of the valve sinus. A subpopulation of platelets that adhered to fibrin expose phosphatidylserine. Platelet-dependent thrombus growth was attenuated by inhibition of glycoprotein VI with a blocking Fab fragment or D-dimer. A 3-step process regulated by hemodynamics was necessary for robust thrombus propagation: First, immobilized tissue factor initiates coagulation and fibrin deposition within a low flow niche defined by a secondary vortex in the pocket of a model venous valve. Second, a primary vortex delivers platelets to the fibrin interface in a red blood cell-dependent manner. Third, platelets adhere to fibrin, activate through glycoprotein VI, express phosphatidylserine, and subsequently promote thrombus growth beyond the valve sinus and into the bulk flow. © 2018 American Heart Association, Inc.

Parasitic momentum flux in the tokamak core

DOE PAGES

Stoltzfus-Dueck, T.

2017-03-06

A geometrical correction to the E × B drift causes an outward flux of co-current momentum whenever electrostatic potential energy is transferred to ion parallel flows. The robust, fully nonlinear symmetry breaking follows from the free-energy flow in phase space and does not depend on any assumed linear eigenmode structure. The resulting rotation peaking is counter-current and scales as temperature over plasma current. Lastly, this peaking mechanism can only act when fluctuations are low-frequency enough to excite ion parallel flows, which may explain some recent experimental observations related to rotation reversals.

Investigation of Multiscale and Multiphase Flow, Transport and Reaction in Heavy Oil Recovery Processes

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yortsos, Yanis C.

In this report, the thrust areas include the following: Internal drives, vapor-liquid flows, combustion and reaction processes, fluid displacements and the effect of instabilities and heterogeneities and the flow of fluids with yield stress. These find respective applications in foamy oils, the evolution of dissolved gas, internal steam drives, the mechanics of concurrent and countercurrent vapor-liquid flows, associated with thermal methods and steam injection, such as SAGD, the in-situ combustion, the upscaling of displacements in heterogeneous media and the flow of foams, Bingham plastics and heavy oils in porous media and the development of wormholes during cold production.

User's guide to the SEPHIS computer code for calculating the Thorex solvent extraction system

DOE Office of Scientific and Technical Information (OSTI.GOV)

Watson, S.B.; Rainey, R.H.

1979-05-01

The SEPHIS computer program was developed to simulate the countercurrent solvent extraction process. The code has now been adapted to model the Acid Thorex flow sheet. This report represents a practical user's guide to SEPHIS - Thorex containing a program description, user information, program listing, and sample input and output.

A "Greenhouse Gas" Experiment for the Undergraduate Laboratory

ERIC Educational Resources Information Center

Gomez, Elaine; Paul, Melissa; Como, Charles; Barat, Robert

2014-01-01

This experiment and analysis offer an effective experience in greenhouse gas reduction. Ammoniated water is flowed counter-current to a simulated flue gas of air and CO2 in a packed column. The gaseous CO2 concentrations are measured with an on-line, non- dispersive, infrared analyzer. Column operating parameters include total gas flux, dissolved…

Countercurrent fixed-bed gasification of biomass at laboratory scale

DOE Office of Scientific and Technical Information (OSTI.GOV)

Di Blasi, C.; Signorelli, G.; Portoricco, G.

1999-07-01

A laboratory-scale countercurrent fixed-bed gasification plant has been designed and constructed to produce data for process modeling and to compare the gasification characteristics of several biomasses (beechwood, nutshells, olive husks, and grape residues). The composition of producer gas and spatial temperature profiles have been measured for biomass gasification at different air flow rates. The gas-heating value always attains a maximum as a function of this operating variable, associated with a decrease of the air-to-fuel ratio. Optical gasification conditions of wood and agricultural residues give rise to comparable gas-heating values, comprised in the range 5--5.5 MJ/Nm{sup 3} with 28--30% CO, 5--7%more » CO{sub 2}, 6--8% H{sub 2}, 1--2% CH{sub 4}, and small amounts of C{sub 2}- hydrocarbons (apart from nitrogen). However, gasification of agricultural residues is more difficult because of bed transport, partial ash sintering, nonuniform flow distribution, and the presence of a muddy phase in the effluents, so that proper pretreatments are needed for largescale applications.« less

A laplace transform-based technique for solving multiscale and multidomain problems: Application to a countercurrent hemodialyzer model.

PubMed

Simon, Laurent

2017-08-01

An integral-based method was employed to evaluate the behavior of a countercurrent hemodialyzer model. Solute transfer from the blood into the dialysate was described by writing mass balance equations over a section of the device. The approach provided Laplace transform concentration profiles on both sides of the membrane. Applications of the final value theorem led to the development of the effective time constants and steady-state concentrations in the exit streams. Transient responses were derived by a numerical inversion algorithm. Simulations show that the period elapsed, before reaching equilibrium in the effluents, decreased when the blood flow rate increased from 0.25 to 0.30 ml/s. The performance index decreased from 0.80 to 0.71 when the blood-to-dialysate flow ratio increased by 20% and increased from 0.80 to 0.85 when this fraction was reduced by 17%. The analytical solution predicted methadone removal in patients undergoing dialysis. Clinicians can use these findings to predict the time required to achieve a target extraction ratio. Copyright © 2017 Elsevier Ltd. All rights reserved.

Two-zone countercurrent smelter system and process

DOEpatents

Cox, J.H.; Fruehan, R.J.; Elliott, J.F.

1995-01-03

A process for continuously smelting iron ore by use of coal to yield molten iron or semi-steel is disclosed. The process comprises the steps of establishing a melt covered by slag; inducing the slag and the molten iron to flow countercurrently to one another, toward opposite ends of the smelter; maintaining iron oxide-reducing conditions in that zone of the smelter towards which the slag flows; maintaining carbon-oxidizing conditions in that zone of the smelter towards which the molten iron flows; continuously or semicontinuously tapping the slag from the reducing zone end of the smelter; continuously or semicontinuously tapping the molten iron from the oxidizing zone end of the smelter; and adding to both zones iron ore, coal, oxygen, and flux at addition rates sufficient to keep the molten iron in the reducing zone substantially saturated with carbon, maintain in the slag being tapped an FeO content of about 5 weight percent or less, and maintain in the molten iron being tapped a carbon content of about 0.5 to 5 weight percent. A slag dam preferably is included in the smelter, to impede the backflow of the slag from the reducing zone to the oxidizing zone. A metal bath dam with one or more flow-through portals also is preferably used, submerged below the slag dam, to impede the backflow of the hot metal. 8 figures.

Two-zone countercurrent smelter system and process

DOEpatents

Cox, James H.; Fruehan, Richard J.; Elliott, deceased, John F.

1995-01-01

A process for continuously smelting iron ore by use of coal to yield molten iron or semi-steel is disclosed. The process comprises the steps of establishing a melt covered by slag; inducing the slag and the molten iron to flow countercurrently to one another, toward opposite ends of the smelter; maintaining iron oxide-reducing conditions in that zone of the smelter towards which the slag flows; maintaining carbon-oxidizing conditions in that zone of the smelter towards which the molten iron flows; continuously or semicontinuously tapping the slag from the reducing zone end of the smelter; continuously or semicontinuously tapping the molten iron from the oxidizing zone end of the smelter; and adding to both zones iron ore, coal, oxygen, and flux at addition rates sufficient to keep the molten iron in the reducing zone substantially saturated with carbon, maintain in the slag being tapped an FeO content of about 5 weight percent or less, and maintain in the molten iron being tapped a carbon content of about 0.5 to 5 weight percent. A slag dam preferably is included in the smelter, to impede the backflow of the slag from the reducing zone to the oxidizing zone. A metal bath dam with one or more flow-through portals also is preferably used, submerged below the slag dam, to impede the backflow of the hot metal.

C1-Continuous relative permeability and hybrid upwind discretization of three phase flow in porous media

NASA Astrophysics Data System (ADS)

Lee, S. H.; Efendiev, Y.

2016-10-01

Three-phase flow in a reservoir model has been a major challenge in simulation studies due to slowly convergent iterations in Newton solution of nonlinear transport equations. In this paper, we examine the numerical characteristics of three-phase flow and propose a consistent, "C1-continuous discretization" (to be clarified later) of transport equations that ensures a convergent solution in finite difference approximation. First, we examine three-phase relative permeabilities that are critical in solving nonlinear transport equations. Three-phase relative permeabilities are difficult to measure in the laboratory, and they are often correlated with two-phase relative permeabilities (e.g., oil-gas and water-oil systems). Numerical convergence of non-linear transport equations entails that three-phase relative permeability correlations are a monotonically increasing function of the phase saturation and the consistency conditions of phase transitions are satisfied. The Modified Stone's Method II and the Linear Interpolation Method for three-phase relative permeability are closely examined for their mathematical properties. We show that the Linear Interpolation Method yields C1-continuous three-phase relative permeabilities for smooth solutions if the two phase relative permeabilities are monotonic and continuously differentiable. In the second part of the paper, we extend a Hybrid-Upwinding (HU) method of two-phase flow (Lee, Efendiev and Tchelepi, ADWR 82 (2015) 27-38) to three phase flow. In the HU method, the phase flux is divided into two parts based on the driving forces (in general, it can be divided into several parts): viscous and buoyancy. The viscous-driven and buoyancy-driven fluxes are upwinded differently. Specifically, the viscous flux, which is always co-current, is upwinded based on the direction of the total velocity. The pure buoyancy-induced flux is shown to be only dependent on saturation distributions and counter-current. In three-phase flow, the buoyancy effect can be expressed as a sum of two buoyancy effects from two-phase flows, i.e., oil-water and oil-gas systems. We propose an upwind scheme for the buoyancy flux term from three-phase flow as a sum of two buoyancy terms from two-phase flows. The upwind direction of the buoyancy flux in two phase flow is always fixed such that the heavier fluid goes downward and the lighter fluid goes upward. It is shown that the Implicit Hybrid-Upwinding (IHU) scheme for three-phase flow is locally conservative and produces physically-consistent numerical solutions. As in two phase flow, the primary advantage of the IHU scheme is that the flux of a fluid phase remains continuous and differentiable as the flow regime changes between co-current and counter-current conditions as a function of time, or (Newton) iterations. This is in contrast to the standard phase-potential-based upwinding scheme, in which the overall fractional-flow (flux) function is non-differentiable across the transition between co-current and counter-current flows.

Passive restriction of blood flow and counter-current heat exchange via lingual retia in the tongue of a neonatal gray whale Eschrichtius robustus (Cetacea, Mysticeti).

PubMed

Ekdale, Eric G; Kienle, Sarah S

2015-04-01

Retia mirabilia play broad roles in cetacean physiology, including thermoregulation during feeding and pressure regulations during diving. Vascular bundles of lingual retia are described within the base of the tongue of a neonatal female gray whale (Eschrichtius robustus). Each rete consists of a central artery surrounded by four to six smaller veins. The retia and constituent vessels decrease in diameter as they extend anteriorly within the hyoglossus muscle from a position anterior to the basihyal cartilage toward the apex of the tongue. The position of the retia embedded in the hyoglossus and the anterior constriction of the vessels differs from reports of similar vascular bundles that were previously identified in gray whales. The retia likely serve as a counter-current heat exchange system to control body temperature during feeding. Cold blood flowing toward the body center within the periarterial veins would accept heat from warm blood in the central artery flowing toward the anterior end of the tongue. Although thermoregulatory systems have been identified within the mouths of a few mysticete species, the distribution of such vascular structures likely is more widespread among baleen whales than has previously been described. © 2015 Wiley Periodicals, Inc.

Non-homogeneous flow profiles in sheared bacterial suspensions

NASA Astrophysics Data System (ADS)

Samanta, Devranjan; Cheng, Xiang

Bacterial suspensions under shear exhibit interesting rheological behaviors including the remarkable ``superfluidic'' state with vanishing viscosity at low shear rates. Theoretical studies have shown that such ``superfluidic'' state is linked with non-homogeneous shear flows, which are induced by coupling between nematic order of active fluids and hydrodynamics of shear flows. However, although bulk rheology of bacterial suspensions has been experimentally studied, shear profiles within bacterial suspensions have not been explored so far. Here, we experimentally investigate the flow behaviors of E. coli suspensions under planar oscillatory shear. Using confocal microscopy and PIV, we measure velocity profiles across gap between two shear plates. We find that with increasing shear rates, high-concentration bacterial suspensions exhibit an array of non-homogeneous flow behaviors like yield-stress flows and shear banding. We show that these non-homogeneous flows are due to collective motion of bacterial suspensions. The phase diagram of sheared bacterial suspensions is systematically mapped as functions of shear rates an bacterial concentrations. Our experiments provide new insights into rheology of bacterial suspensions and shed light on shear induced dynamics of active fluids. Chemical Engineering and Material Science department.

Convective heater

DOEpatents

Thorogood, Robert M.

1986-01-01

A convective heater for heating fluids such as a coal slurry is constructed of a tube circuit arrangement which obtains an optimum temperature distribution to give a relatively constant slurry film temperature. The heater is constructed to divide the heating gas flow into two equal paths and the tube circuit for the slurry is arranged to provide a mixed flow configuration whereby the slurry passes through the two heating gas paths in successive co-current, counter-current and co-current flow relative to the heating gas flow. This arrangement permits the utilization of minimum surface area for a given maximum film temperature of the slurry consistent with the prevention of coke formation.

Convective heater

DOEpatents

Thorogood, Robert M.

1983-01-01

A convective heater for heating fluids such as a coal slurry is constructed of a tube circuit arrangement which obtains an optimum temperature distribution to give a relatively constant slurry film temperature. The heater is constructed to divide the heating gas flow into two equal paths and the tube circuit for the slurry is arranged to provide a mixed flow configuration whereby the slurry passes through the two heating gas paths in successive co-current, counter-current and co-current flow relative to the heating gas flow. This arrangement permits the utilization of minimum surface area for a given maximum film temperature of the slurry consistent with the prevention of coke formation.

Convective heater

DOEpatents

Thorogood, R.M.

1983-12-27

A convective heater for heating fluids such as a coal slurry is constructed of a tube circuit arrangement which obtains an optimum temperature distribution to give a relatively constant slurry film temperature. The heater is constructed to divide the heating gas flow into two equal paths and the tube circuit for the slurry is arranged to provide a mixed flow configuration whereby the slurry passes through the two heating gas paths in successive co-current, counter-current and co-current flow relative to the heating gas flow. This arrangement permits the utilization of minimum surface area for a given maximum film temperature of the slurry consistent with the prevention of coke formation. 14 figs.

Caanyon Mediated Cross-Slope Transport

NASA Astrophysics Data System (ADS)

Mihaly, S. F.; Cabrera De Leo, F.; Sastri, A. R.; Matabos, M.; Heesemann, M.; Ogata, B.

2017-12-01

Three current meter and water property stations along the west coast of Vancouver Island along with video and acoustic backscatter observations are used to gain insight into mechanisms of cross-slope transport. The setting is an eastern boundary current region with a active poleward flowing countercurrent. The significant effects of these currents flowing over a strongly incised continental slope along with cross-slope density flows are contrasted with the seasonally varying upwelling and downwelling regime. The video and acoustic backscatter enabled by Ocean Networks Canada's NEPTUNE observatory provide a view on the materials being transported between the abyssal plain and the continental shelf.

Current-oriented swimming by jellyfish and its role in bloom maintenance.

PubMed

Fossette, Sabrina; Gleiss, Adrian Christopher; Chalumeau, Julien; Bastian, Thomas; Armstrong, Claire Denise; Vandenabeele, Sylvie; Karpytchev, Mikhail; Hays, Graeme Clive

2015-02-02

Cross-flows (winds or currents) affect animal movements [1-3]. Animals can temporarily be carried off course or permanently carried away from their preferred habitat by drift depending on their own traveling speed in relation to that of the flow [1]. Animals able to only weakly fly or swim will be the most impacted (e.g., [4]). To circumvent this problem, animals must be able to detect the effects of flow on their movements and respond to it [1, 2]. Here, we show that a weakly swimming organism, the jellyfish Rhizostoma octopus, can orientate its movements with respect to currents and that this behavior is key to the maintenance of blooms and essential to reduce the probability of stranding. We combined in situ observations with first-time deployment of accelerometers on free-ranging jellyfish and simulated the behavior observed in wild jellyfish within a high-resolution hydrodynamic model. Our results show that jellyfish can actively swim countercurrent in response to current drift, leading to significant life-history benefits, i.e., increased chance of survival and facilitated bloom formation. Current-oriented swimming may be achieved by jellyfish either directly detecting current shear across their body surface [5] or indirectly assessing drift direction using other cues (e.g., magnetic, infrasound). Our coupled behavioral-hydrodynamic model provides new evidence that current-oriented swimming contributes to jellyfish being able to form aggregations of hundreds to millions of individuals for up to several months, which may have substantial ecosystem and socioeconomic consequences [6, 7]. It also contributes to improve predictions of jellyfish blooms' magnitude and movements in coastal waters. Copyright © 2015 Elsevier Ltd. All rights reserved.

New analytical spiral tube assembly for separation of proteins by counter-current chromatography.

PubMed

Ma, Xiaofeng; Ito, Yoichiro

2015-07-31

A new spiral column assembly for analytical separation by counter-current chromatography is described. The column is made from a plastic spiral tube support which has 12 interwoven spiral grooves. The PTFE tubing of 1.6mm ID was first flattened by extruding through a narrow slit and inserted into the grooves to make 5 spiral layers with about 60ml capacity. The performance of the spiral column assembly was tested with separation of three stable protein samples including cytochrome C, myoglobin and lysozyme in a polymer phase system composed of polyethylene glycol 1000 and dibasic potassium phosphate each at 12.5% (w/w) in water. At 2ml/min, three protein samples were well resolved in 1h. The separation time may be further shortened by application of higher revolution speed and flow rate by improving the strength of the spiral tube support in the future. Published by Elsevier B.V.

Countercurrent direct contact heat exchange process and system

DOEpatents

Wahl, III, Edward F.; Boucher, Frederic B.

1979-01-01

Recovery of energy from geothermal brines and other hot water sources by direct contact heat exchange with a working fluid, such as a hydrocarbon working fluid, e.g. isobutane. The process and system consists of a plurality of stages, each stage including mixing and settling units. In the first stage, hot brine and arm working fluid are intimately mixed and passed into a settler wherein the brine settles to the bottom of the settler and the hot working fluid rises to the top. The hot working fluid is passed to a heat engine or turbine to produce work and the working fluid is then recycled back into the system. The system is comprised of a series of stages each containing a settler and mixer, and wherein the working fluid and the brine flow in a countercurrent manner through the stages to recover the heat from the brine in increments and raise the temperature of the working fluid in increments.

Reflux cooling experiments on the NCSU scaled PWR facility

DOE Office of Scientific and Technical Information (OSTI.GOV)

Doster, J.M.; Giavedoni, E.

1993-01-01

Under loss of forced circulation, coupled with the loss or reduction in primary side coolant inventory, horizontal stratified flows can develop in the hot and cold legs of pressurized water reactors (PWRs). Vapor produced in the reactor vessel is transported through the hot leg to the steam generator tubes where it condenses and flows back to the reactor vessel. Within the steam generator tubes, the flow regimes may range from countercurrent annular flow to single-phase convection. As a result, a number of heat transfer mechanisms are possible, depending on the loop configuration, total heat transfer rate, and the steam flowmore » rate within the tubes. These include (but are not limited to) two-phase natural circulation, where the condensate flows concurrent to the vapor stream and is transported to the cold leg so that the entire reactor coolant loop is active, and reflux cooling, where the condensate flows back down the interior of the coolant tubes countercurrent to the vapor stream and is returned to the reactor vessel through the hot leg. While operating in the reflux cooling mode, the cold leg can effectively be inactive. Heat transfer can be further influenced by noncondensables in the vapor stream, which accumulate within the upper regions of the steam generator tube bundle. In addition to reducing the steam generator's effective heat transfer area, under these conditions operation under natural circulation may not be possible, and reflux cooling may be the only viable heat transfer mechanism. The scaled PWR (SPWR) facility in the nuclear engineering department at North Carolina State Univ. (NCSU) is being used to study the effectiveness of two-phase natural circulation and reflux cooling under conditions associated with loss of forced circulation, midloop coolant levels, and noncondensables in the primary coolant system.« less

Interaction of monopoles, dipoles, and turbulence with a shear flow

NASA Astrophysics Data System (ADS)

Marques Rosas Fernandes, V. H.; Kamp, L. P. J.; van Heijst, G. J. F.; Clercx, H. J. H.

2016-09-01

Direct numerical simulations have been conducted to examine the evolution of eddies in the presence of large-scale shear flows. The numerical experiments consist of initial-value-problems in which monopolar and dipolar vortices as well as driven turbulence are superposed on a plane Couette or Poiseuille flow in a periodic two-dimensional channel. The evolution of the flow has been examined for different shear rates of the background flow and different widths of the channel. Results found for retro-grade and pro-grade monopolar vortices are consistent with those found in the literature. Boundary layer vorticity, however, can significantly modify the straining and erosion of monopolar vortices normally seen for unbounded domains. Dipolar vortices are shown to be much more robust coherent structures in a large-scale shear flow than monopolar eddies. An analytical model for their trajectories, which are determined by self-advection and advection and rotation by the shear flow, is presented. Turbulent kinetic energy is effectively suppressed by the shearing action of the background flow provided that the shear is linear (Couette flow) and of sufficient strength. Nonlinear shear as present in the Poiseuille flow seems to even increase the turbulence strength especially for high shear rates.

On the self-organizing process of large scale shear flows

DOE Office of Scientific and Technical Information (OSTI.GOV)

Newton, Andrew P. L.; Kim, Eun-jin; Liu, Han-Li

2013-09-15

Self organization is invoked as a paradigm to explore the processes governing the evolution of shear flows. By examining the probability density function (PDF) of the local flow gradient (shear), we show that shear flows reach a quasi-equilibrium state as its growth of shear is balanced by shear relaxation. Specifically, the PDFs of the local shear are calculated numerically and analytically in reduced 1D and 0D models, where the PDFs are shown to converge to a bimodal distribution in the case of finite correlated temporal forcing. This bimodal PDF is then shown to be reproduced in nonlinear simulation of 2Dmore » hydrodynamic turbulence. Furthermore, the bimodal PDF is demonstrated to result from a self-organizing shear flow with linear profile. Similar bimodal structure and linear profile of the shear flow are observed in gulf stream, suggesting self-organization.« less

Downhole steam generator having a downhole oxidant compressor

DOEpatents

Fox, Ronald L.

1983-01-01

Apparatus and method for generation of steam in a borehole for penetration into an earth formation wherein a downhole oxidant compressor is used to compress relatively low pressure (atmospheric) oxidant, such as air, to a relatively high pressure prior to mixing with fuel for combustion. The multi-stage compressor receives motive power through a shaft driven by a gas turbine powered by the hot expanding combustion gases. The main flow of compressed oxidant passes through a velocity increasing nozzle formed by a reduced central section of the compressor housing. An oxidant bypass feedpipe leading to peripheral oxidant injection nozzles of the combustion chamber are also provided. The downhole compressor allows effective steam generation in deep wells without need for high pressure surface compressors. Feedback preheater means are provided for preheating fuel in a preheat chamber. Preheating of the water occurs in both a water feed line running from aboveground and in a countercurrent water flow channel surrounding the combustor assembly. The countercurrent water flow channels advantageously serve to cool the combustion chamber wall. The water is injected through slotted inlets along the combustion chamber wall to provide an unstable boundary layer and stripping of the water from the wall for efficient steam generation. Pressure responsive doors are provided at the steam outlet for closing and sealing the combustion chamber from entry of reservoir fluids in the event of a flameout.

Purification of monoclonal antibodies from clarified cell culture fluid using Protein A capture continuous countercurrent tangential chromatography

PubMed Central

Dutta, Amit K.; Tran, Travis; Napadensky, Boris; Teella, Achyuta; Brookhart, Gary; Ropp, Philip A.; Zhang, Ada W.; Tustian, Andrew D.; Zydney, Andrew L.; Shinkazh, Oleg

2015-01-01

Recent studies using simple model systems have demonstrated that Continuous Countercurrent Tangential Chromatography (CCTC) has the potential to overcome many of the limitations of conventional Protein A chromatography using packed columns. The objective of this work was to optimize and implement a CCTC system for monoclonal antibody purification from clarified Chinese Hamster Ovary (CHO) cell culture fluid using a commercial Protein A resin. Several improvements were introduced to the previous CCTC system including the use of retentate pumps to maintain stable resin concentrations in the flowing slurry, the elimination of a slurry holding tank to improve productivity, and the introduction of an “after binder” to the binding step to increase antibody recovery. A kinetic binding model was developed to estimate the required residence times in the multi-stage binding step to optimize yield and productivity. Data were obtained by purifying two commercial antibodies from two different manufactures, one with low titer (~0.67 g/L) and one with high titer (~6.9 g/L), demonstrating the versatility of the CCTC system. Host cell protein removal, antibody yields and purities were similar to that obtained with conventional column chromatography; however, the CCTC system showed much higher productivity. These results clearly demonstrate the capabilities of continuous countercurrent tangential chromatography for the commercial purification of monoclonal antibody products. PMID:25747172

Purification of monoclonal antibodies from clarified cell culture fluid using Protein A capture continuous countercurrent tangential chromatography.

PubMed

Dutta, Amit K; Tran, Travis; Napadensky, Boris; Teella, Achyuta; Brookhart, Gary; Ropp, Philip A; Zhang, Ada W; Tustian, Andrew D; Zydney, Andrew L; Shinkazh, Oleg

2015-11-10

Recent studies using simple model systems have demonstrated that continuous countercurrent tangential chromatography (CCTC) has the potential to overcome many of the limitations of conventional Protein A chromatography using packed columns. The objective of this work was to optimize and implement a CCTC system for monoclonal antibody purification from clarified Chinese Hamster Ovary (CHO) cell culture fluid using a commercial Protein A resin. Several improvements were introduced to the previous CCTC system including the use of retentate pumps to maintain stable resin concentrations in the flowing slurry, the elimination of a slurry holding tank to improve productivity, and the introduction of an "after binder" to the binding step to increase antibody recovery. A kinetic binding model was developed to estimate the required residence times in the multi-stage binding step to optimize yield and productivity. Data were obtained by purifying two commercial antibodies from two different manufactures, one with low titer (∼ 0.67 g/L) and one with high titer (∼ 6.9 g/L), demonstrating the versatility of the CCTC system. Host cell protein removal, antibody yields and purities were similar to those obtained with conventional column chromatography; however, the CCTC system showed much higher productivity. These results clearly demonstrate the capabilities of continuous countercurrent tangential chromatography for the commercial purification of monoclonal antibody products. Copyright © 2015 Elsevier B.V. All rights reserved.

The temporal evolution of the resistive pressure-gradient-driven turbulence and anomalous transport in shear flow across the magnetic field

NASA Astrophysics Data System (ADS)

Lee, Hae June; Mikhailenko, Vladmir; Mikhailenko, Vladimir

2017-10-01

The temporal evolution of the resistive pressure-gradient-driven mode in the sheared flow is investigated by employing the shearing modes approach. It reveals an essential difference in the processes, which occur in the case of the flows with velocity shearing rate less than the growth rate of the instability in the steady plasmas, and in the case of the flows with velocity shear larger than the instability growth rate in steady plasmas. It displays the physical content of the empirical ``quench rule'' which predicts the suppression of the turbulence in the sheared flows when the velocity shearing rate becomes larger than the maximum growth rate of the possible instability. We found that the distortion of the perturbations by the sheared flow with such velocity shear introduces the time dependencies into the governing equations, which prohibits the application of the eigenmodes formalism and requires the solution of the initial value problem.

Measurement of Wall Shear Stress in High Speed Air Flow Using Shear-Sensitive Liquid Crystal Coating.

PubMed

Zhao, Jisong

2018-05-17

Wall shear stress is an important quantity in fluid mechanics, but its measurement is a challenging task. An approach to measure wall shear stress vector distribution using shear-sensitive liquid crystal coating (SSLCC) is described. The wall shear stress distribution on the test surface beneath high speed jet flow is measured while using the proposed technique. The flow structures inside the jet flow are captured and the results agree well with the streakline pattern that was visualized using the oil-flow technique. In addition, the shock diamonds inside the supersonic jet flow are visualized clearly using SSLCC and the results are compared with the velocity contour that was measured using the particle image velocimetry (PIV) technique. The work of this paper demonstrates the application of SSLCC in the measurement/visualization of wall shear stress in high speed flow.

Measurement of Wall Shear Stress in High Speed Air Flow Using Shear-Sensitive Liquid Crystal Coating

PubMed Central

Zhao, Jisong

2018-01-01

Wall shear stress is an important quantity in fluid mechanics, but its measurement is a challenging task. An approach to measure wall shear stress vector distribution using shear-sensitive liquid crystal coating (SSLCC) is described. The wall shear stress distribution on the test surface beneath high speed jet flow is measured while using the proposed technique. The flow structures inside the jet flow are captured and the results agree well with the streakline pattern that was visualized using the oil-flow technique. In addition, the shock diamonds inside the supersonic jet flow are visualized clearly using SSLCC and the results are compared with the velocity contour that was measured using the particle image velocimetry (PIV) technique. The work of this paper demonstrates the application of SSLCC in the measurement/visualization of wall shear stress in high speed flow. PMID:29772822

Hydrodynamic Stability Analysis on Sheared Stratified Flow in a Convective Flow Environment

NASA Astrophysics Data System (ADS)

Xiao, Yuan; Lin, Wenxian; Armfiled, Steven; Kirkpatrick, Michael; He, Yinghe; Fluid Dynamics Research Group, James Cook University Team; Fluid Dynamics Research Group, University of Sydney Team

2014-11-01

A hydrodynamic stability analysis on the convective sheared boundary layer (SCBL) flow, where a sheared stratified flow and a thermally convective flow coexist, is carried out in this study. The linear unstable stratifications representing the convective flow are included in the TaylorGoldstein equations as an unstable factor Jb. A new unstable region corresponding to the convective instability, which is not present in pure sheared stratified flows, is found with the analysis. It is also found that the boundaries of the convective instability regions expand with increasing Jb and interact with the sheared stratified instability region. More results will be presented at the conference

Isolation of dimeric, trimeric, tetrameric and pentameric procyanidins from unroasted cocoa beans (Theobroma cacao L.) using countercurrent chromatography.

PubMed

Esatbeyoglu, Tuba; Wray, Victor; Winterhalter, Peter

2015-07-15

The main procyanidins, including dimeric B2 and B5, trimeric C1, tetrameric and pentameric procyanidins, were isolated from unroasted cocoa beans (Theobroma cacao L.) using various techniques of countercurrent chromatography, such as high-speed countercurrent chromatography (HSCCC), low-speed rotary countercurrent chromatography (LSRCCC) and spiral-coil LSRCCC. Furthermore, dimeric procyanidins B1 and B7, which are not present naturally in the analysed cocoa beans, were obtained after semisynthesis of cocoa bean polymers with (+)-catechin as nucleophile and separated by countercurrent chromatography. In this way, the isolation of dimeric procyanidin B1 in considerable amounts (500mg, purity>97%) was possible in a single run. This is the first report concerning the isolation and semisynthesis of dimeric to pentameric procyanidins from T. cacao by countercurrent chromatography. Additionally, the chemical structures of tetrameric (cinnamtannin A2) and pentameric procyanidins (cinnamtannin A3) were elucidated on the basis of (1)H NMR spectroscopy. Interflavanoid linkage was determined by NOE-correlations, for the first time. Copyright © 2015 Elsevier Ltd. All rights reserved.

Transient shear banding in the nematic dumbbell model of liquid crystalline polymers

NASA Astrophysics Data System (ADS)

Adams, J. M.; Corbett, D.

2018-05-01

In the shear flow of liquid crystalline polymers (LCPs) the nematic director orientation can align with the flow direction for some materials but continuously tumble in others. The nematic dumbbell (ND) model was originally developed to describe the rheology of flow-aligning semiflexible LCPs, and flow-aligning LCPs are the focus in this paper. In the shear flow of monodomain LCPs, it is usually assumed that the spatial distribution of the velocity is uniform. This is in contrast to polymer solutions, where highly nonuniform spatial velocity profiles have been observed in experiments. We analyze the ND model, with an additional gradient term in the constitutive model, using a linear stability analysis. We investigate the separate cases of constant applied shear stress and constant applied shear rate. We find that the ND model has a transient flow instability to the formation of a spatially inhomogeneous flow velocity for certain starting orientations of the director. We calculate the spatially resolved flow profile in both constant applied stress and constant applied shear rate in start up from rest, using a model with one spatial dimension to illustrate the flow behavior of the fluid. For low shear rates flow reversal can be seen as the director realigns with the flow direction, whereas for high shear rates the director reorientation occurs simultaneously across the gap. Experimentally, this inhomogeneous flow is predicted to be observed in flow reversal experiments in LCPs.

Turbulence modeling in simulation of gas-turbine flow and heat transfer.

PubMed

Brereton, G; Shih, T I

2001-05-01

The popular k-epsilon type two-equation turbulence models, which are calibrated by experimental data from simple shear flows, are analyzed for their ability to predict flows involving shear and an extra strain--flow with shear and rotation and flow with shear and streamline curvature. The analysis is based on comparisons between model predictions and those from measurements and large-eddy simulations of homogenous flows involving shear and an extra strain, either from rotation or from streamline curvature. Parameters are identified, which show the conditions under which performance of k-epsilon type models can be expected to be poor.

Rheology of dilute cohesive granular gases

NASA Astrophysics Data System (ADS)

Takada, Satoshi; Hayakawa, Hisao

2018-04-01

Rheology of a dilute cohesive granular gas is theoretically and numerically studied. The flow curve between the shear viscosity and the shear rate is derived from the inelastic Boltzmann equation for particles having square-well potentials in a simple shear flow. It is found that (i) the stable uniformly sheared state only exists above a critical shear rate and (ii) the viscosity in the uniformly sheared flow is almost identical to that for uniformly sheared flow of hard core granular particles. Below the critical shear rate, clusters grow with time, in which the viscosity can be approximated by that for the hard-core fluids if we replace the diameter of the particle by the mean diameter of clusters.

Thermally conductive porous element-based recuperators

NASA Technical Reports Server (NTRS)

Du, Jian Hua (Inventor); Chow, Louis C (Inventor); Lin, Yeong-Ren (Inventor); Wu, Wei (Inventor); Kapat, Jayanta (Inventor); Notardonato, William U. (Inventor)

2012-01-01

A heat exchanger includes at least one hot fluid flow channel comprising a first plurality of open cell porous elements having first gaps there between for flowing a hot fluid in a flow direction and at least one cold fluid flow channel comprising a second plurality of open cell porous elements having second gaps therebetween for flowing a cold fluid in a countercurrent flow direction relative to the flow direction. The thermal conductivity of the porous elements is at least 10 W/mK. A separation member is interposed between the hot and cold flow channels for isolating flow paths associated these flow channels. The first and second plurality of porous elements at least partially overlap one another to form a plurality of heat transfer pairs which transfer heat from respective ones of the first porous elements to respective ones of the second porous elements through the separation member.

[Advances in studies on multi-stage countercurrent extraction technology in traditional Chinese medicine].

PubMed

Xie, Zhi-Peng; Liu, Xue-Song; Chen, Yong; Cai, Ming; Qu, Hai-Bin; Cheng, Yi-Yu

2007-05-01

Multi-stage countercurrent extraction technology, integrating solvent extraction, repercolation with dynamic and countercurrent extraction, is a novel extraction technology for the traditional Chinese medicine. This solvent-saving, energy-saving and high-extraction-efficiency technology can at the most drive active compounds to diffuse from the herbal materials into the solvent stage by stage by creating concentration differences between the herbal materials and the solvents. This paper reviewed the basic principle, the influence factors and the research progress and trends of the equipments and the application of the multi-stage countercurrent extraction.

Experimental Study of the Vortex-Induced Vibration of Drilling Risers under the Shear Flow with the Same Shear Parameter at the Different Reynolds Numbers

PubMed Central

Liangjie, Mao; Qingyou, Liu; Shouwei, Zhou

2014-01-01

A considerable number of studies for VIV under the uniform flow have been performed. However, research on VIV under shear flow is scarce. An experiment for VIV under the shear flow with the same shear parameter at the two different Reynolds numbers was conducted in a deep-water offshore basin. Various measurements were obtained by the fiber bragg grating strain sensors. Experimental data were analyzed by modal analysis method. Results show several valuable features. First, the corresponding maximum order mode of the natural frequency for shedding frequency is the maximum dominant vibration mode and multi-modal phenomenon is appeared in VIV under the shear flow, and multi-modal phenomenon is more apparent at the same shear parameter with an increasing Reynolds number under the shear flow effect. Secondly, the riser vibrates at the natural frequency and the dominant vibration frequency increases for the effect of the real-time tension amplitude under the shear flow and the IL vibration frequency is the similar with the CF vibration frequency at the Reynolds number of 1105 in our experimental condition and the IL dominant frequency is twice the CF dominant frequency with an increasing Reynolds number. In addition, the displacement trajectories at the different locations of the riser appear the same shape and the shape is changed at the same shear parameter with an increasing Reynolds number under the shear flow. The diagonal displacement trajectories are observed at the low Reynolds number and the crescent-shaped displacement trajectories appear with an increasing Reynolds number under shear flow in the experiment. PMID:25118607

Experimental study of the vortex-induced vibration of drilling risers under the shear flow with the same shear parameter at the different Reynolds numbers.

PubMed

Liangjie, Mao; Qingyou, Liu; Shouwei, Zhou

2014-01-01

A considerable number of studies for VIV under the uniform flow have been performed. However, research on VIV under shear flow is scarce. An experiment for VIV under the shear flow with the same shear parameter at the two different Reynolds numbers was conducted in a deep-water offshore basin. Various measurements were obtained by the fiber bragg grating strain sensors. Experimental data were analyzed by modal analysis method. Results show several valuable features. First, the corresponding maximum order mode of the natural frequency for shedding frequency is the maximum dominant vibration mode and multi-modal phenomenon is appeared in VIV under the shear flow, and multi-modal phenomenon is more apparent at the same shear parameter with an increasing Reynolds number under the shear flow effect. Secondly, the riser vibrates at the natural frequency and the dominant vibration frequency increases for the effect of the real-time tension amplitude under the shear flow and the IL vibration frequency is the similar with the CF vibration frequency at the Reynolds number of 1105 in our experimental condition and the IL dominant frequency is twice the CF dominant frequency with an increasing Reynolds number. In addition, the displacement trajectories at the different locations of the riser appear the same shape and the shape is changed at the same shear parameter with an increasing Reynolds number under the shear flow. The diagonal displacement trajectories are observed at the low Reynolds number and the crescent-shaped displacement trajectories appear with an increasing Reynolds number under shear flow in the experiment.

On the Pathways of the Return Flow of the Meridional Overturning Circulation in the Tropical Atlantic

NASA Technical Reports Server (NTRS)

Jochum, Markus

2002-01-01

A numerical model of the tropical Atlantic ocean is used to investigate the upper layer pathways of the Meridional Overturning Circulation (MOC) in the tropical Atlantic. The main focus of this thesis is on those parts of the tropical circulation that are thought to be important for the MOC return flow, but whose dynamics have not been understood yet. It is shown how the particular structure of the tropical gyre and the MOO act to inhibit the flow of North Atlantic water into the equatorial thermocline. As a result, the upper layers of the tropical Atlantic are mainly fed by water from the South Atlantic. The processes that carry the South Atlantic water across the tropical Atlantic into the North Atlantic as part of the MOO are described here, and three processes that were hitherto not understood are explained as follows: The North Brazil Current rings are created as the result of the reflection of Rossby waves at the South American coast. These Rossby waves are generated by the barotropically unstable North Equatorial Countercurrent. The deep structure of the rings can be explained by merger of the wave's anticyclones with the deeper intermediate eddies that are generated as the intermediate western boundary current crosses the equator. The bands of strong zonal velocity in intermediate depths along the equator have hitherto been explained as intermediate currents. Here, an alternative interpretation of the observations is offered: The Eulerian mean flow along the equator is negligible and the observations are the signature of strong seasonal Rossby waves. The previous interpretation of the observations can then be explained as aliasing of the tropical wave field. The Tsuchyia Jets are driven by the Eliassen-Palm flux of the tropical instability waves. The equatorial current system with its strong shears is unstable and generates tropical instability waves.

The Effect of a Shear Flow on the Uptake of LDL and Ac-LDL by Cultured Vascular Endothelial Cells

NASA Astrophysics Data System (ADS)

Niwa, Koichi; Karino, Takeshi

The effects of a shear flow on the uptake of fluorescence-labeled low-density lipoprotein (DiI-LDL), acetylated LDL (DiI-Ac-LDL), and lucifer yellow (LY; a tracer of fluid-phase endocytosis) by cultured bovine aortic ECs were studied using a rotating-disk shearing apparatus. It was found that 2hours’ exposure of ECs to a laminar shear flow that imposed ECs an area-mean shear stress of 10dynes/cm2 caused an increase in the uptake of DiI-LDL and LY. By contrast, the uptake of DiI-Ac-LDL was decreased by exposure of the ECs to a shear flow. Addition of dextran sulfate (DS), a competitive inhibitor of scavenger receptors, reversed the effect of a shear flow on the uptake of DiI-Ac-LDL, resulting in an increase by the imposition of a shear flow, while the uptake of DiI-LDL and LY remained unaffected. It was concluded that a shear flow promotes the endocytosis of DiI-LDL and LY by ECs, but suppresses the uptake of DiI-Ac-LDL by ECs by inhibiting scavenger receptor-mediated endocytosis.

Anomalous Diffusion of Particles Dispersed in Xanthan Solutions Subjected to Shear Flow

NASA Astrophysics Data System (ADS)

Takikawa, Yoshinori; Yasuta, Muneharu; Fujii, Shuji; Orihara, Hiroshi; Tanaka, Yoshimi; Nishinari, Katsuyoshi

2018-05-01

Xanthan gum exhibits viscoelastic and shear-thinning properties. We investigate the Brownian motion of particles dispersed in xanthan gum solutions that are subjected to simple shear flow. The mean square displacements (MSDs) are obtained in both the flow and vorticity directions. In the absence of shear flow, subdiffusion is observed, MSD ∝ tα with α < 1, where t is time. In the presence of shear flow, however, the exponent α becomes larger together with the MSD itself in both the flow and vorticity directions. We show that the diffusion is enhanced by Taylor dispersion in the flow direction, whereas in the vorticity direction it is enhanced by nonthermal self-diffusion.

Molecular shear heating and vortex dynamics in thermostatted two dimensional Yukawa liquids

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gupta, Akanksha; Ganesh, Rajaraman, E-mail: ganesh@ipr.res.in; Joy, Ashwin

2016-07-15

It is well known that two-dimensional macroscale shear flows are susceptible to instabilities leading to macroscale vortical structures. The linear and nonlinear fate of such a macroscale flow in a strongly coupled medium is a fundamental problem. A popular example of a strongly coupled medium is a dusty plasma, often modelled as a Yukawa liquid. Recently, laboratory experiments and molecular dynamics (MD) studies of shear flows in strongly coupled Yukawa liquids indicated the occurrence of strong molecular shear heating, which is found to reduce the coupling strength exponentially leading to the destruction of macroscale vorticity. To understand the vortex dynamicsmore » of strongly coupled molecular fluids undergoing macroscale shear flows and molecular shear heating, MD simulation has been performed, which allows the macroscopic vortex dynamics to evolve, while at the same time “removes” the microscopically generated heat without using the velocity degrees of freedom. We demonstrate that by using a configurational thermostat in a novel way, the microscale heat generated by shear flow can be thermostatted out efficiently without compromising the large scale vortex dynamics. In the present work, using MD simulations, a comparative study of shear flow evolution in Yukawa liquids in the presence and absence of molecular or microscopic heating is presented for a prototype shear flow, namely, Kolmogorov flow.« less

Research on wall shear stress considering wall roughness when shear swirling flow vibration cementing

NASA Astrophysics Data System (ADS)

Cui, Zhihua; Ai, Chi; Feng, Fuping

2017-01-01

When shear swirling flow vibration cementing, the casing is revolving periodically and eccentrically, which leads to the annulus fluid in turbulent swirling flow state. The wall shear stress is more than that in laminar flow field when conventional cementing. The paper mainly studied the wall shear stress distribution on the borehole wall when shear swirling flow vibration cementing based on the finite volume method. At the same time, the wall roughness affected and changed the turbulent flow near the borehole wall and the wall shear stress. Based on the wall function method, the paper established boundary conditions considering the wall roughness and derived the formula of the wall shear stress. The results showed that the wall roughness significantly increases the wall shear stress. However, the larger the wall roughness, the greater the thickness of mud cake, which weakening the cementing strength. Considering the effects in a comprehensive way, it is discovered that the particle size of solid phase in drilling fluid is about 0.1 mm to get better cementing quality.

Shear flow of one-component polarizable fluid in a strong electric field

NASA Astrophysics Data System (ADS)

Sun, J. M.; Tao, R.

1996-04-01

A shear flow of one-component polarizable fluid in a strong electric field has a structural transition at a critical shear stress. When the shear stress is increased from zero up to the critical shear stress, the flow (in the x direction) has a flowing-chain (FC) structure, consisting of tilted or broken chains along the field (z direction). At the critical shear stress, the FC structure gives way to a flowing-hexagonal-layered (FHL) structure, consisting of several two-dimensional layers which are parallel to the x-z plane. Within one layer, particles form strings in the flow direction. Strings are constantly sliding over particles in strings right beneath. The effective viscosity drops dramatically at the structural change. As the shear stress reduces, the FHL structure persists even under a stress-free state if the thermal fluctuation is very weak. This structure change in the charging and discharging process produces a large hysteresis.

Preparative isolation and purification of hainanmurpanin, meranzin, and phebalosin from leaves of Murraya exotica L. using supercritical fluid extraction combined with consecutive high-speed countercurrent chromatography.

PubMed

Yan, Rongwei; Shen, Jie; Liu, Xiaojing; Zou, Yong; Xu, Xinjun

2018-05-01

The objective of this study was to develop a consecutive preparation method for the isolation and purification of hainanmurpanin, meranzin, and phebalosin from leaves of Murraya exotica L. The process involved supercritical fluid extraction with CO 2 , solvent extraction, and two-step high-speed countercurrent chromatography. Pressure, temperature, and the volume of entrainer were optimized as 27 MPa, 52°C, and 60 mL by response surface methodology in supercritical fluid extraction with CO 2 , and the yield of the crude extracts was 7.91 g from 100 g of leaves. Subsequently, 80% methanol/water was used to extract and condense the three compounds from the crude extracts, and 4.23 g of methanol/water extracts was obtained. Then, a two-step high-speed countercurrent chromatography procedure was developed for the isolation of the three target compounds from methanol/water extracts, including conventional high-speed countercurrent chromatography for further enrichment and consecutive high-speed countercurrent chromatography for purification. The yield of concentrates from high-speed countercurrent chromatography was 2.50 g from 4.23 g of methanol/water extracts. Finally, the consecutive high-speed countercurrent chromatography produced 103.2 mg of hainanmurpanin, 244.7 mg of meranzin, and 255.4 mg of phebalosin with purities up to 97.66, 99.36, and 98.64%, respectively, from 900 mg of high-speed countercurrent chromatography concentrates in one run of three consecutive sample loadings without exchanging a solvent system. © 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Free turbulent shear flows. Volume 2: Summary of data

NASA Technical Reports Server (NTRS)

Birch, S. F.

1973-01-01

The proceedings of a conference on free turbulent shear flows are presented. Objectives of the conference are as follows: (1) collect and process data for a variety of free mixing problems, (2) assess present theoretical capability for predicting mean velocity, concentration, and temperature distributions in free turbulent flows, (3) identify and recommend experimental studies to advance knowledge of free shear flows, and (4) increase understanding of basic turbulent mixing process for application to free shear flows. Examples of specific cases of jet flow are included.

Modeling and measuring non-Newtonian shear flows of soft interfaces

NASA Astrophysics Data System (ADS)

Lopez, Juan; Raghunandan, Aditya; Underhill, Patrick; Hirsa, Amir

2017-11-01

Soft interfaces of polymers, particles, and proteins between fluid phases are ubiquitous in industrial and natural processes. The flow response of such systems to deformation is often not linear, as one would expect for Newtonian interfaces. The resistance to (pure shear) flow of interfaces is generally characterized by a single intrinsic material property, the surface shear viscosity. Predicted shear responses of Newtonian interfaces have achieved consensus across a wide range of flow conditions and measurement devices, when the nonlinear hydrodynamic coupling to the bulk phase is correctly accounted for. However, predicting the flows of sheared non-Newtonian interfaces remains a challenge. Here, we introduce a computational model that incorporates a non-Newtonian constitutive equation for the sheared interface and properly accounts for the coupled interfacial and bulk phase flows. We compare predictions to experiments performed with a model phospholipid system, DPPC - the main constituent of mammalian lung surfactant. Densely packed films of DPPC are directly sheared in a knife-edge surface viscometer. Yield-stress and shear thinning behaviors are shown to be accurately captured across hydrodynamic regimes straddling the Stokes flow limit to inertia dominated flows. Supported by NASA Grant NNX13AQ22G.

The 9th International Countercurrent Chromatography Conference held at Dominican University, Chicago, USA, August 1-3, 2016.

PubMed

Friesen, J Brent; McAlpine, James B; Chen, Shao-Nong; Pauli, Guido F

2017-10-20

The 9th International Countercurrent Chromatography Conference (CCC 2016) was held at Dominican University near Chicago, IL (USA), from August 1st-3rd, 2016. The biennial CCC 20XX conferences provide an opportunity for countercurrent chromatography and centrifugal partition chromatography (CCC/CPC) manufactures, marketers, theorists, and research scientists to gather together socially, learn from each other, and advance countercurrent separation technology. A synopsis of the conference proceedings as well as a series of short reviews of the special edition articles is included in this document. Many productive discussions and collegial conversation at CCC 2016 attested to the liveliness, connectivity, and productivity of the global countercurrent research community and bodes well for the success of the 10th conference at the University of Braunschweig, Germany on August 1-3, 2018. Copyright © 2017 Elsevier B.V. All rights reserved.

Spiral counter-current chromatography: Design, development, application, and challenges.

PubMed

Huang, Xin-Yi; Sun, Xiao-Ming; Pei, Dong; Di, Duo-Long

2017-01-01

Depending on the rapid growth in the radial gradient of the centrifugal force, spiral counter-current chromatography can greatly improve the retention of stationary phase, especially for the aqueous two-phase systems with ultra-polar and high viscosity that are not well retained in the conventional multilayer coils counter-current chromatography. As a result, it is an attractive and alternative technology that is suited for separation of hydrophilic compounds and has led to many exciting progress in recent years. This review presents the recent advances and applications of spiral counter-current chromatography, including its major benefits and limitations, some novel methods to improve the separation efficiency and its applications in separation of real samples. In addition, the remaining challenges and future perspectives on development of spiral counter-current chromatography also are proposed in this article. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

How pattern is selected in drift wave turbulence: Role of parallel flow shear

NASA Astrophysics Data System (ADS)

Kosuga, Y.

2017-12-01

The role of parallel shear flow in the pattern selection problem in drift wave turbulence is discussed. Patterns of interest here are E × B convective cells, which include poloidally symmetric zonal flows and radially elongated streamers. The competition between zonal flow formation and streamer formation is analyzed in the context of modulational instability analysis, with the parallel flow shear as a parameter. For drift wave turbulence with k⊥ρs ≲ O (1 ) and without parallel flow coupling, zonal flows are preferred structures. While increasing the magnitude of parallel flow shear, streamer growth overcomes zonal flow growth. This is because the self-focusing effect of the modulational instability becomes more effective for streamers through density and parallel velocity modulation. As a consequence, the bursty release of free energy may result as the parallel flow shear increases.

Formation of structural steady states in lamellar/sponge phase-separating fluids under shear flow

NASA Astrophysics Data System (ADS)

Panizza, P.; Courbin, L.; Cristobal, G.; Rouch, J.; Narayanan, T.

2003-05-01

We investigate the effect of shear flow on a lamellar-sponge phase-separating fluid when subjected to shear flow. We show the existence of two different steady states (droplets and ribbons structures) whose nature does not depend on the way to reach the two-phase unstable region of the phase diagram (temperature quench or stirring). The transition between ribbons and droplets is shear thickening and its nature strongly depends on what dynamical variable is imposed. If the stress is fixed, flow visualization shows the existence of shear bands at the transition, characteristic of coexistence in the cell between ribbons and droplets. In this shear-banding region, the viscosity oscillates. When the shear rate is fixed, no shear bands are observed. Instead, the transition exhibits a hysteretic behavior leading to a structural bi-stability of the phase-separating fluid under flow.

Origin of shear thickening in semidilute wormlike micellar solutions and evidence of elastic turbulence

DOE Office of Scientific and Technical Information (OSTI.GOV)

Marín-Santibáñez, Benjamín M.; Pérez-González, José, E-mail: jpg@esfm.ipn.mx; Rodríguez-González, Francisco

2014-11-01

The origin of shear thickening in an equimolar semidilute wormlike micellar solution of cetylpyridinium chloride and sodium salicylate was investigated in this work by using Couette rheometry, flow visualization, and capillary Rheo-particle image velocimetry. The use of the combined methods allowed the discovery of gradient shear banding flow occurring from a critical shear stress and consisting of two main bands, one isotropic (transparent) of high viscosity and one structured (turbid) of low viscosity. Mechanical rheometry indicated macroscopic shear thinning behavior in the shear banding regime. However, local velocimetry showed that the turbid band increased its viscosity along with the shearmore » stress, even though barely reached the value of the viscosity of the isotropic phase. This shear band is the precursor of shear induced structures that subsequently give rise to the average increase in viscosity or apparent shear thickening of the solution. Further increase in the shear stress promoted the growing of the turbid band across the flow region and led to destabilization of the shear banding flow independently of the type of rheometer used, as well as to vorticity banding in Couette flow. At last, vorticity banding disappeared and the flow developed elastic turbulence with chaotic dynamics.« less

GASEOUS DISPOSAL PROCESS

DOEpatents

Ryan, R.F.; Thomasson, F.R.; Hicks, J.H.

1963-01-22

A method is described of removing gaseous radioactive Xe and Kr from water containing O. The method consists in stripping the gases from the water stream by means of H flowing countercurrently to the stream. The gases are then heated in a deoxo bed to remove O. The carrier gas is next cooled and passed over a charcoal adsorbent bed maintained at a temperature of about --280 deg F to remove the Xe and Kr. (AEC)

Semi-industrial isolation of salicin and amygdalin from plant extracts using slow rotary counter-current chromatography.

PubMed

Du, Qizhen; Jerz, Gerold; Ha, Yangchun; Li, Lei; Xu, Yuanjin; Zhang, Qi; Zheng, Qunxiong; Winterhalter, Peterb; Ito, Yoichiro

2005-05-13

Salicin in the bark extract of Salix alba and amygdalin in the fruit extract of Semen armeniacae were each separated by slow rotary counter-current chromatography (SRCCC). The apparatus was equipped with a 40-L column made of 17 mm i.d. convoluted Teflon tubing. A 500g amount of crude extract containing salicin at 13.5% was separated yielding 63.5 g of salicin at 95.3% purity in 20h using methyl tert-butyl ether-l-butanol (1:3) saturated by methanol-water (1:5) as a stationary phase and methanol-water (1:5) saturated by methyl tert-butyl ether-1-butanol (1:3) as a mobile phase. A 400g amount of crude extract containing amygdalin at 55.3% was isolated to yield 221.2g of amygdalin at 94.1% purity in 19h using ethyl acetate-1-butanol (1:2) saturated by water as a stationary phase and water saturated by ethyl acetate-1-butanol (1:2) as a mobile phase. The flow rate of the mobile phase was 50 ml/min. The results show that industrial SRCCC separation of salicin and amygdalin is feasible using a larger column at a higher flow rate of the mobile phase.

Revisiting resolution in hydrodynamic countercurrent chromatography: tubing bore effect.

PubMed

Berthod, A; Faure, K

2015-04-17

A major challenge in countercurrent chromatography (CCC), the technique that works with a support-free biphasic liquid system, is to retain the liquid stationary phase inside the CCC column (Sf parameter). Two solutions are commercially available: the hydrostatic CCC columns, also called centrifugal partition chromatographs (CPC), with disks of interconnected channels and rotary seals, and the hydrodynamic CCC columns with bobbins of coiled open tube and no rotary seals. It was demonstrated that the amount of liquid stationary phase retained by a coiled tube was higher with larger bore tubing than with small bore tubes. At constant column volume, small bore tubing will be longer producing more efficiency than larger bore tube that will better retain the liquid stationary phase. Since the resolution equation in CCC is depending on both column efficiency and stationary phase retention ratio, the influence of the tubing bore should be studied. This theoretical work showed that there is an optimum tubing bore size depending on solute partition coefficient and mobile phase flow rate. The interesting result of the theoretical study is that larger tubing bores allow for dramatically reduced experiment durations for all solutes: in reversed phase CCC (polar mobile phase), hydrophobic solutes are usually highly retained. These apolar solutes can be separated by the same coil at high flow rates and reduced Sf with similar retention times as polar solutes separated at smaller flow rates and much higher Sf. Copyright © 2015 Elsevier B.V. All rights reserved.

A mathematical model for the iron/chromium redox battery

NASA Technical Reports Server (NTRS)

Fedkiw, P. S.; Watts, R. W.

1984-01-01

A mathematical model has been developed to describe the isothermal operation of a single anode-separator-cathode unit cell in a redox-flow battery and has been applied to the NASA iron/chromium system. The model, based on porous electrode theory, incorporates redox kinetics, mass transfer, and ohmic effects as well as the parasitic hydrogen reaction which occurs in the chromium electrode. A numerical parameter study was carried out to predict cell performance to aid in the rational design, scale-up, and operation of the flow battery. The calculations demonstrate: (1) an optimum electrode thickness and electrolyte flow rate exist; (2) the amount of hydrogen evolved and, hence, cycle faradaic efficiency, can be affected by cell geometry, flow rate, and charging procedure; (3) countercurrent flow results in enhanced cell performance over cocurrent flow; and (4) elevated temperature operation enhances cell performance.

Microalga propels along vorticity direction in a shear flow

NASA Astrophysics Data System (ADS)

Chengala, Anwar; Hondzo, Miki; Sheng, Jian

2013-05-01

Using high-speed digital holographic microscopy and microfluidics, we discover that, when encountering fluid flow shear above a threshold, unicellular green alga Dunaliella primolecta migrates unambiguously in the cross-stream direction that is normal to the plane of shear and coincides with the local fluid flow vorticity. The flow shear drives motile microalgae to collectively migrate in a thin two-dimensional horizontal plane and consequently alters the spatial distribution of microalgal cells within a given suspension. This shear-induced algal migration differs substantially from periodic rotational motion of passive ellipsoids, known as Jeffery orbits, as well as gyrotaxis by bottom-heavy swimming microalgae in a shear flow due to the subtle interplay between torques generated by gravity and viscous shear. Our findings could facilitate mechanistic solutions for modeling planktonic thin layers and sustainable cultivation of microalgae for human nutrition and bioenergy feedstock.

Separation and purification of triterpene saponins from roots of Radix phytolaccae by high-speed countercurrent chromatography coupled with evaporative light scattering detection

PubMed Central

Ma, Jie; Chen, Qianliang; Lai, Daowan; Sun, Wenji; Zhang, Tianyou; Ito, Yoichiro

2009-01-01

Coupled with evaporative light scattering detection, high-speed countercurrent chromatography was successfully applied for the first time to separation and purification of four triterpene saponins including esculentoside A, B, C and D from roots of Radix Phytolaccae. The separation was performed with an optimized two-phase solvent system composed of chloroform-methanol-water (4:4:2, v/v) using the lower phase as the mobile phase at a flow rate of 1.5 ml/min,. From 150 mg of crude extract 46.3 mg of esculentoside A, 21.8 mg of esculentoside B, 7.3 mg of esculentoside C, and 13.6 mg of esculentoside D were obtained at purities of 96.7%, 99.2%, 96.5% and 97.8%, respectively, as determined by HPLC analysis. The structures of the four triterpene saponins were identified by ESI-MS,1H NMR and 13C NMR. PMID:20454595

Colonization of the Hawaiian Archipelago via Johnston Atoll: a characterization of oceanographic transport corridors for pelagic larvae using computer simulation

NASA Astrophysics Data System (ADS)

Kobayashi, Donald R.

2006-08-01

Larval transport between Johnston Atoll and the Hawaiian Archipelago was examined using computer simulation and high-resolution ocean current data. The effects of pelagic larval duration and spawning seasonality on long-distance transport and local retention were examined using a Lagrangian, individual-based approach. Retention around Johnston Atoll appeared to be low, and there appeared to be seasonal effects on both retention and dispersal. Potential larval transport corridors between Johnston Atoll and the Hawaiian Archipelago were charted. One corridor connects Johnston Atoll with the middle portion of the Hawaiian Archipelago in the vicinity of French Frigate Shoals. Another corridor connects Johnston Atoll with the lower inhabited islands in the vicinity of Kauai. Transport appears to be related to the subtropical countercurrent and the Hawaiian Lee countercurrent, both located to the west of the archipelago and flowing to the east. A new analytical tool, termed CONREC-IRC is presented for the quantification of spatial patterns.

Circulating moving bed system for CO.sub.2 separation, and method of same

DOEpatents

Elliott, Jeannine Elizabeth; Copeland, Robert James

2016-12-27

A circulating moving bed and process for separating a carbon dioxide from a gas stream is disclosed. The circulating moving bed can include an adsorption reactor and a desorption reactor, and a sorbent that moves through the two reactors. The sorbent can enter the adsorptive reactor and one end and move to an exit point distal to its entry point, while a CO.sub.2 feed stream can enter near the distal point and move countercurrently through the sorbent to exit at a position near the entry point of the sorbent. The sorbent can adsorb the CO.sub.2 by concentration swing adsorption and adsorptive displacement. The sorbent can then transfer to a regeneration reactor and can move countercurrently against a flow of steam through the regeneration reactor. The sorbent can be regenerated and the carbon dioxide recaptured by desorbing the carbon dioxide from the sorbent using concentration swing desorption and desorptive displacement with steam.

Separation of polyphenols and caffeine from the acetone extract of fermented tea leaves (Camellia sinensis) using high-performance countercurrent chromatography.

PubMed

Choi, Soo Jung; Hong, Yong Deog; Lee, Bumjin; Park, Jun Seong; Jeong, Hyun Woo; Kim, Wan Gi; Shin, Song Seok; Yoon, Kee Dong

2015-07-21

Leaves from Camellia sienensis are a popular natural source of various beverage worldwide, and contain caffeine and polyphenols derived from catechin analogues. In the current study, caffeine (CAF, 1) and three tea polyphenols including (-)-epigallocatechin 3-O-gallate (EGCg, 2), (-)-gallocatechin 3-O-gallate (GCg, 3), and (-)-epicatechin 3-O-gallate (ECg, 4) were isolated and purified by flow-rate gradient high-performance countercurrent chromatography (HPCCC) using a two-phase solvent system composed of n-hexane-ethyl acetate-methanol-water (1:9:1:9, v/v). Two hundred milligrams of acetone-soluble extract from fermented C. sinensis leaves was separated by HPCCC to give 1 (25.4 mg), 2 (16.3 mg), 3 (11.1 mg) and 4 (4.4 mg) with purities over 98%. The structures of 1-4 were elucidated by QTOF-MS, as well as 1H- and 13C-NMR, and the obtained data were compared to the previously reported values.

Influence of equilibrium shear flow in the parallel magnetic direction on edge localized mode crash

DOE Office of Scientific and Technical Information (OSTI.GOV)

Luo, Y.; Xiong, Y. Y.; Chen, S. Y., E-mail: sychen531@163.com

2016-04-15

The influence of the parallel shear flow on the evolution of peeling-ballooning (P-B) modes is studied with the BOUT++ four-field code in this paper. The parallel shear flow has different effects in linear simulation and nonlinear simulation. In the linear simulations, the growth rate of edge localized mode (ELM) can be increased by Kelvin-Helmholtz term, which can be caused by the parallel shear flow. In the nonlinear simulations, the results accord with the linear simulations in the linear phase. However, the ELM size is reduced by the parallel shear flow in the beginning of the turbulence phase, which is recognizedmore » as the P-B filaments' structure. Then during the turbulence phase, the ELM size is decreased by the shear flow.« less

Effects of planar shear on the three-dimensional instability in flow past a circular cylinder

NASA Astrophysics Data System (ADS)

Park, Doohyun; Yang, Kyung-Soo

2018-03-01

A Floquet stability analysis has been carried out in order to investigate how a planar shear in wake flow affects the three-dimensional (3D) instability in the near-wake region. We consider a circular cylinder immersed in a freestream with planar shear. The cylinder was implemented in a Cartesian grid system by means of an immersed boundary method. Planar shear tends to promote the primary instability, known as Hopf bifurcation where steady flow bifurcates into time-periodic flow, in the sense that its critical Reynolds number decreases with increasing planar shear. The effects of planar shear on the 3D instability are different depending on the type of 3D instability. The flow asymmetry caused by the planar shear suppresses a QP-type mode but generates a C-type mode. The conventional A and B modes are stabilized by the planar shear, whereas mode C is intensified with increasing shear. The criticality of each 3D mode is discussed, and the neutral stability curves for each 3D mode are presented. The current Floquet results have been validated by using direct numerical simulation for some selected cases of flow parameters.

Shear Wave Wavefront Mapping Using Ultrasound Color Flow Imaging.

PubMed

Yamakoshi, Yoshiki; Kasahara, Toshihiro; Iijima, Tomohiro; Yuminaka, Yasushi

2015-10-01

A wavefront reconstruction method for a continuous shear wave is proposed. The method uses ultrasound color flow imaging (CFI) to detect the shear wave's wavefront. When the shear wave vibration frequency satisfies the required frequency condition and the displacement amplitude satisfies the displacement amplitude condition, zero and maximum flow velocities appear at the shear wave vibration phases of zero and π rad, respectively. These specific flow velocities produce the shear wave's wavefront map in CFI. An important feature of this method is that the shear wave propagation is observed in real time without addition of extra functions to the ultrasound imaging system. The experiments are performed using a 6.5 MHz CFI system. The shear wave is excited by a multilayer piezoelectric actuator. In a phantom experiment, the shear wave velocities estimated using the proposed method and those estimated using a system based on displacement measurement show good agreement. © The Author(s) 2015.

Inverse design of centrifugal compressor vaned diffusers in inlet shear flows

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zangeneh, M.

1996-04-01

A three-dimensional inverse design method in which the blade (or vane) geometry is designed for specified distributions of circulation and blade thickness is applied to the design of centrifugal compressor vaned diffusers. Two generic diffusers are designed, one with uniform inlet flow (equivalent to a conventional design) and the other with a sheared inlet flow. The inlet shear flow effects are modeled in the design method by using the so-called ``Secondary Flow Approximation`` in which the Bernoulli surfaces are convected by the tangentially mean inviscid flow field. The difference between the vane geometry of the uniform inlet flow and nonuniformmore » inlet flow diffusers is found to be most significant from 50 percent chord to the trailing edge region. The flows through both diffusers are computed by using Denton`s three-dimensional inviscid Euler solver and Dawes` three-dimensional Navier-Stokes solver under sheared in-flow conditions. The predictions indicate improved pressure recovery and internal flow field for the diffuser designed for shear inlet flow conditions.« less

Performance characterization of a cross-flow hydrokinetic turbine in sheared inflow

DOE Office of Scientific and Technical Information (OSTI.GOV)

Forbush, Dominic; Polagye, Brian; Thomson, Jim

2016-12-01

A method for constructing a non-dimensional performance curve for a cross-flow hydrokinetic turbine in sheared flow is developed for a natural river site. The river flow characteristics are quasi-steady, with negligible vertical shear, persistent lateral shear, and synoptic changes dominated by long time scales (days to weeks). Performance curves developed from inflow velocities measured at individual points (randomly sampled) yield inconclusive turbine performance characteristics because of the spatial variation in mean flow. Performance curves using temporally- and spatially-averaged inflow velocities are more conclusive. The implications of sheared inflow are considered in terms of resource assessment and turbine control.

Non-canonical Wnt signalling modulates the endothelial shear stress flow sensor in vascular remodelling

PubMed Central

Franco, Claudio A; Jones, Martin L; Bernabeu, Miguel O; Vion, Anne-Clemence; Barbacena, Pedro; Fan, Jieqing; Mathivet, Thomas; Fonseca, Catarina G; Ragab, Anan; Yamaguchi, Terry P; Coveney, Peter V; Lang, Richard A; Gerhardt, Holger

2016-01-01

Endothelial cells respond to molecular and physical forces in development and vascular homeostasis. Deregulation of endothelial responses to flow-induced shear is believed to contribute to many aspects of cardiovascular diseases including atherosclerosis. However, how molecular signals and shear-mediated physical forces integrate to regulate vascular patterning is poorly understood. Here we show that endothelial non-canonical Wnt signalling regulates endothelial sensitivity to shear forces. Loss of Wnt5a/Wnt11 renders endothelial cells more sensitive to shear, resulting in axial polarization and migration against flow at lower shear levels. Integration of flow modelling and polarity analysis in entire vascular networks demonstrates that polarization against flow is achieved differentially in artery, vein, capillaries and the primitive sprouting front. Collectively our data suggest that non-canonical Wnt signalling stabilizes forming vascular networks by reducing endothelial shear sensitivity, thus keeping vessels open under low flow conditions that prevail in the primitive plexus. DOI: http://dx.doi.org/10.7554/eLife.07727.001 PMID:26845523

Cholesteric-nematic transitions induced by a shear flow and a magnetic field

NASA Astrophysics Data System (ADS)

Zakhlevnykh, A. N.; Makarov, D. V.; Novikov, A. A.

2017-10-01

The untwisting of the helical structure of a cholesteric liquid crystal under the action of a magnetic field and a shear flow has been studied theoretically. Both factors can induce the cholesteric-nematic transition independently; however, the difference in the orienting actions of the magnetic field and the shear flow leads to competition between magnetic and hydrodynamic mechanisms of influence on the cholesteric liquid crystal. We have analyzed different orientations of the magnetic field relative to the direction of the flow in the shear plane. In a number of limiting cases, the analytic dependences are obtained for the pitch of the cholesteric helix deformed by the shear flow. The phase diagrams of the cholesteric-nematic transitions and the pitch of the cholesteric helix are calculated for different values of the magnetic field strength and the angle of orientation, the flow velocity gradient, and the reactive parameter. It is shown that the magnetic field stabilizes the orientation of the director in the shear flow and expands the boundaries of orientability of cholesterics. It has been established that the shear flow shifts the critical magnetic field strength of the transition. It is shown that a sequence of reentrant orientational cholesteric-nematic-cholesteric transitions can be induced by rotating the magnetic field in certain intervals of its strength and shear flow velocity gradients.

Two-axis direct fluid shear stress sensor

NASA Technical Reports Server (NTRS)

Bajikar, Sateesh (Inventor); Scott, Michael A. (Inventor); Adcock, Edward E. (Inventor)

2011-01-01

A micro sized multi-axis semiconductor skin friction/wall shear stress induced by fluid flow. The sensor design includes a shear/strain transduction gimble connected to a force collecting plate located at the flow boundary surface. The shear force collecting plate is interconnected by an arm to offset the tortional hinges from the fluid flow. The arm is connected to the shear force collecting plate through dual axis torsional hinges with piezoresistive torsional strain gauges. These gauges are disposed on the tortional hinges and provide a voltage output indicative of applied shear stress acting on the force collection plate proximate the flow boundary surface. Offsetting the torsional hinges creates a force concentration and resolution structure that enables the generation of a large stress on the strain gauge from small shear stress, or small displacement of the collecting plate. The design also isolates the torsional sensors from exposure to the fluid flow.

Structural state diagram of concentrated suspensions of jammed soft particles in oscillatory shear flow

NASA Astrophysics Data System (ADS)

Khabaz, Fardin; Cloitre, Michel; Bonnecaze, Roger T.

2018-03-01

In a recent study [Khabaz et al., Phys. Rev. Fluids 2, 093301 (2017), 10.1103/PhysRevFluids.2.093301], we showed that jammed soft particle glasses (SPGs) crystallize and order in steady shear flow. Here we investigate the rheology and microstructures of these suspensions in oscillatory shear flow using particle-dynamics simulations. The microstructures in both types of flows are similar, but their evolutions are very different. In both cases the monodisperse and polydisperse suspensions form crystalline and layered structures, respectively, at high shear rates. The crystals obtained in the oscillatory shear flow show fewer defects compared to those in the steady shear. SPGs remain glassy for maximum oscillatory strains less than about the yield strain of the material. For maximum strains greater than the yield strain, microstructural and rheological transitions occur for SPGs. Polydisperse SPGs rearrange into a layered structure parallel to the flow-vorticity plane for sufficiently high maximum shear rates and maximum strains about 10 times greater than the yield strain. Monodisperse suspensions form a face-centered cubic (FCC) structure when the maximum shear rate is low and hexagonal close-packed (HCP) structure when the maximum shear rate is high. In steady shear, the transition from a glassy state to a layered one for polydisperse suspensions included a significant induction strain before the transformation. In oscillatory shear, the transformation begins to occur immediately and with different microstructural changes. A state diagram for suspensions in large amplitude oscillatory shear flow is found to be in close but not exact agreement with the state diagram for steady shear flow. For more modest amplitudes of around one to five times the yield strain, there is a transition from a glassy structure to FCC and HCP crystals, at low and high frequencies, respectively, for monodisperse suspensions. At moderate frequencies, the transition is from glassy to HCP via an intermediate FCC phase.

Doppler optical coherence tomography imaging of local fluid flow and shear stress within microporous scaffolds

NASA Astrophysics Data System (ADS)

Jia, Yali; Bagnaninchi, Pierre O.; Yang, Ying; Haj, Alicia El; Hinds, Monica T.; Kirkpatrick, Sean J.; Wang, Ruikang K.

2009-05-01

Establishing a relationship between perfusion rate and fluid shear stress in a 3D cell culture environment is an ongoing and challenging task faced by tissue engineers. We explore Doppler optical coherence tomography (DOCT) as a potential imaging tool for in situ monitoring of local fluid flow profiles inside porous chitosan scaffolds. From the measured fluid flow profiles, the fluid shear stresses are evaluated. We examine the localized fluid flow and shear stress within low- and high-porosity chitosan scaffolds, which are subjected to a constant input flow rate of 0.5 ml.min-1. The DOCT results show that the behavior of the fluid flow and shear stress in micropores is strongly dependent on the micropore interconnectivity, porosity, and size of pores within the scaffold. For low-porosity and high-porosity chitosan scaffolds examined, the measured local fluid flow and shear stress varied from micropore to micropore, with a mean shear stress of 0.49+/-0.3 dyn.cm-2 and 0.38+/-0.2 dyn.cm-2, respectively. In addition, we show that the scaffold's porosity and interconnectivity can be quantified by combining analyses of the 3D structural and flow images obtained from DOCT.

Predicting equilibrium states with Reynolds stress closures in channel flow and homogeneous shear flow

NASA Technical Reports Server (NTRS)

Abid, R.; Speziale, C. G.

1993-01-01

Turbulent channel flow and homogeneous shear flow have served as basic building block flows for the testing and calibration of Reynolds stress models. A direct theoretical connection is made between homogeneous shear flow in equilibrium and the log-layer of fully-developed turbulent channel flow. It is shown that if a second-order closure model is calibrated to yield good equilibrium values for homogeneous shear flow it will also yield good results for the log-layer of channel flow provided that the Rotta coefficient is not too far removed from one. Most of the commonly used second-order closure models introduce an ad hoc wall reflection term in order to mask deficient predictions for the log-layer of channel flow that arise either from an inaccurate calibration of homogeneous shear flow or from the use of a Rotta coefficient that is too large. Illustrative model calculations are presented to demonstrate this point which has important implications for turbulence modeling.

Predicting equilibrium states with Reynolds stress closures in channel flow and homogeneous shear flow

NASA Technical Reports Server (NTRS)

Abid, R.; Speziale, C. G.

1992-01-01

Turbulent channel flow and homogeneous shear flow have served as basic building block flows for the testing and calibration of Reynolds stress models. A direct theoretical connection is made between homogeneous shear flow in equilibrium and the log-layer of fully-developed turbulent channel flow. It is shown that if a second-order closure model is calibrated to yield good equilibrium values for homogeneous shear flow it will also yield good results for the log-layer of channel flow provided that the Rotta coefficient is not too far removed from one. Most of the commonly used second-order closure models introduce an ad hoc wall reflection term in order to mask deficient predictions for the log-layer of channel flow that arise either from an inaccurate calibration of homogeneous shear flow or from the use of a Rotta coefficient that is too large. Illustrative model calculations are presented to demonstrate this point which has important implications for turbulence modeling.

Observation of turbulent-driven shear flow in a cylindrical laboratory plasma device.

PubMed

Holland, C; Yu, J H; James, A; Nishijima, D; Shimada, M; Taheri, N; Tynan, G R

2006-05-19

An azimuthally symmetric radially sheared plasma fluid flow is observed to spontaneously form in a cylindrical magnetized helicon plasma device with no external sources of momentum input. A turbulent momentum conservation analysis shows that this shear flow is sustained by the Reynolds stress generated by collisional drift turbulence in the device. The results provide direct experimental support for the basic theoretical picture of drift-wave-shear-flow interactions.

Instabilities in wormlike micelle systems. From shear-banding to elastic turbulence.

PubMed

Fardin, M-A; Lerouge, S

2012-09-01

Shear-banding is ubiquitous in complex fluids. It is related to the organization of the flow into macroscopic bands bearing different viscosities and local shear rates and stacked along the velocity gradient direction. This flow-induced transition towards a heterogeneous flow state has been reported in a variety of systems, including wormlike micellar solutions, telechelic polymers, emulsions, clay suspensions, colloidal gels, star polymers, granular materials, or foams. In the past twenty years, shear-banding flows have been probed by various techniques, such as rheometry, velocimetry and flow birefringence. In wormlike micelle solutions, many of the data collected exhibit unexplained spatio-temporal fluctuations. Different candidates have been identified, the main ones being wall slip, interfacial instability between bands or bulk instability of one of the bands. In this review, we present experimental evidence for a purely elastic instability of the high shear rate band as the main origin for fluctuating shear-banding flows.

Counter-current acid leaching process for copper azole treated wood waste.

PubMed

Janin, Amélie; Riche, Pauline; Blais, Jean-François; Mercier, Guy; Cooper, Paul; Morris, Paul

2012-09-01

This study explores the performance of a counter-current leaching process (CCLP) for copper extraction from copper azole treated wood waste for recycling of wood and copper. The leaching process uses three acid leaching steps with 0.1 M H2SO4 at 75degrees C and 15% slurry density followed by three rinses with water. Copper is recovered from the leachate using electrodeposition at 5 amperes (A) for 75 min. Ten counter-current remediation cycles were completed achieving > or = 94% copper extraction from the wood during the 10 cycles; 80-90% of the copper was recovered from the extract solution by electrodeposition. The counter-current leaching process reduced acid consumption by 86% and effluent discharge volume was 12 times lower compared with the same process without use of counter-current leaching. However, the reuse of leachates from one leaching step to another released dissolved organic carbon and caused its build-up in the early cycles.

Highly elastic polymer solutions under shear: Polymer migration, viscoelastic instabilities, and anomalous rheology

DOE Office of Scientific and Technical Information (OSTI.GOV)

MacDonald, M.J.; Muller, S.J.

1996-12-31

The use of highly elastic polymer solutions has been remarkably successful in elucidating the behavior of polymeric materials under flowing conditions. Here, we present the results of an extensive experimental study into the shear behavior of an athermal, dilute, binary polymer solution that is believed to be free of many of these effects. Under extended shearing, we observe the migration of polymer species: after shearing for several hundred hours, concentrations that are more than double the initial uniform value can be achieved. Although the solutions are well-described by dumbbell models in shear flows on short-time scales, theoretical predictions substantially underestimatemore » the rate of migration. Flow visualization and rheometric experiments suggest that the origin of this discrepancy could be the anomalous long-time rheology of these solutions. While these fluids display the well-known elastic instability in cone and plate flow above a critical Deborah number, extended shearing reveals that the toroidal secondary flow is eventually replaced by a purely azimuthal shearing flow. In addition, when sheared below the critical condition for the instability, the solutions exhibit a slow but reversible decay in normal stresses. The shear-induced migration of polymer species has been predicted by numerous theoretical studies. However, observations on the highly elastic polymer solutions that are most likely to show polymer migration, are complicated by a number of different physical processes that occur as a result of shearing. These phenomena, which include shear-induced phase separation, elastically-induced hydrodynamic instabilities, mixed solvent effects, shear-induced aggregation, and anomalous transient shear and normal stress behavior are often observed at times earlier than and at shear rates less than those where migration is predicted to occur; hence, the experimental detection of polymer migration has been thwarted by these other physical processes.« less

Pressurized liquid extraction coupled with countercurrent chromatography for systematic isolation of chemical constituents by preprogrammed automatic control.

PubMed

Zhang, Yuchi; Guo, Liping; Liu, Chunming; Fu, Zi' ao; Cong, Lei; Qi, Yanjuan; Li, Dongping; Li, Sainan; Wang, Jing

2013-09-15

Pressurized liquid extraction (PLE) coupled with high-speed countercurrent chromatography (HSCCC) via an automated procedure was firstly developed to extract and isolate ginsenosides from Panax quinquefolium. The experiments were designed under the guidance of mathematical model. The partition coefficient (K) values of the target compounds and resolutions of peak profiles were employed as the research indicators, and exponential function and binomial formulas were used to optimizing the solvent systems and flow rates of the mobile phases in a three-stage separation. In the first stage, ethyl acetate, n-butanol, and water were simultaneously pumped into the solvent separator at the flow rates 11.0, 10.0, and 23.0mL/min, respectively. The upper phase of the solvent system in the solvent separator was used as both the PLE solvent and the HSCCC stationary phase, followed by elution with the lower phase of the corresponding solvent system to separate the common ginsenosides. In the second and third stages, rare ginsenosides were first separated by elution with ethyl acetate, n-butanol, methanol, and water (flow rates: 20.0, 3.0, 5.0, and 11.0mL/min, respectively), then with n-heptane, n-butanol, methanol, and water (flow rates: 17.5, 6.0, 5.0, and 22.5mL/min, respectively). Nine target compounds, with purities exceeding 95.0%, and three non-target compounds, with purities above 84.48%, were successfully separated at the semipreparative scale in 450min. The separation results prove that the PLE/HSCCC parameters calculated via mathematical model and formulas were accurately and scientifically. This research has opened up great prospects for industrial automation application. Copyright © 2013 Elsevier B.V. All rights reserved.

Injectable Solid Peptide Hydrogel as Cell Carrier: Effects of Shear Flow on Hydrogel and Cell Payload

PubMed Central

Yan, Congqi; Mackay, Michael E.; Czymmek, Kirk; Nagarkar, Radhika P.; Schneider, Joel P.; Pochan, Darrin J.

2012-01-01

β-hairpin peptide-based hydrogels are a class of injectable solid hydrogels that can deliver encapsulated cells or molecular therapies to a target site via syringe or catheter injection as a carrier material. These physical hydrogels can shear-thin and consequently flow as a low-viscosity material under a sufficient shear stress but immediately recover back into a solid upon removal of the stress, allowing them to be injected as preformed gel solids. Hydrogel behavior during flow was studied in a cylindrical capillary geometry that mimicked the actual situation of injection through a syringe needle in order to quantify effects of shear-thin injection delivery on hydrogel flow behavior and encapsulated cell payloads. It was observed that all β-hairpin peptide hydrogels investigated displayed a promising flow profile for injectable cell delivery: a central wide plug flow region where gel material and cell payloads experienced little or no shear rate and a narrow shear zone close to the capillary wall where gel and cells were subject to shear deformation. The width of the plug flow region was found to be weakly dependent on hydrogel rigidity and flow rate. Live-dead assays were performed on encapsulated MG63 cells three hours after injection flow and revealed that shear-thin delivery through the capillary had little impact on cell viability and the spatial distribution of encapsulated cell payloads. These observations help us to fundamentally understand how the gels flow during injection through a thin catheter and how they immediately restore mechanically and morphologically relative to pre-flow, static gels. PMID:22390812

Shear-induced crystallization of a dense rapid granular flow: hydrodynamics beyond the melting point.

PubMed

Khain, Evgeniy; Meerson, Baruch

2006-06-01

We investigate shear-induced crystallization in a very dense flow of monodisperse inelastic hard spheres. We consider a steady plane Couette flow under constant pressure and neglect gravity. We assume that the granular density is greater than the melting point of the equilibrium phase diagram of elastic hard spheres. We employ a Navier-Stokes hydrodynamics with constitutive relations all of which (except the shear viscosity) diverge at the crystal-packing density, while the shear viscosity diverges at a smaller density. The phase diagram of the steady flow is described by three parameters: an effective Mach number, a scaled energy loss parameter, and an integer number m: the number of half-oscillations in a mechanical analogy that appears in this problem. In a steady shear flow the viscous heating is balanced by energy dissipation via inelastic collisions. This balance can have different forms, producing either a uniform shear flow or a variety of more complicated, nonlinear density, velocity, and temperature profiles. In particular, the model predicts a variety of multilayer two-phase steady shear flows with sharp interphase boundaries. Such a flow may include a few zero-shear (solidlike) layers, each of which moving as a whole, separated by fluidlike regions. As we are dealing with a hard sphere model, the granulate is fluidized within the "solid" layers: the granular temperature is nonzero there, and there is energy flow through the boundaries of the solid layers. A linear stability analysis of the uniform steady shear flow is performed, and a plausible bifurcation diagram of the system, for a fixed m, is suggested. The problem of selection of m remains open.

Chirality-specific lift forces of helix under shear flows: Helix perpendicular to shear plane.

PubMed

Zhang, Qi-Yi

2017-02-01

Chiral objects in shear flow experience a chirality-specific lift force. Shear flows past helices in a low Reynolds number regime were studied using slender-body theory. The chirality-specific lift forces in the vorticity direction experienced by helices are dominated by a set of helix geometry parameters: helix radius, pitch length, number of turns, and helix phase angle. Its analytical formula is given. The chirality-specific forces are the physical reasons for the chiral separation of helices in shear flow. Our results are well supported by the latest experimental observations. © 2016 Wiley Periodicals, Inc.

Plasma rotation and transport in MAST spherical tokamak

NASA Astrophysics Data System (ADS)

Field, A. R.; Michael, C.; Akers, R. J.; Candy, J.; Colyer, G.; Guttenfelder, W.; Ghim, Y.-c.; Roach, C. M.; Saarelma, S.; MAST Team

2011-06-01

The formation of internal transport barriers (ITBs) is investigated in MAST spherical tokamak plasmas. The relative importance of equilibrium flow shear and magnetic shear in their formation and evolution is investigated using data from high-resolution kinetic- and q-profile diagnostics. In L-mode plasmas, with co-current directed NBI heating, ITBs in the momentum and ion thermal channels form in the negative shear region just inside qmin. In the ITB region the anomalous ion thermal transport is suppressed, with ion thermal transport close to the neo-classical level, although the electron transport remains anomalous. Linear stability analysis with the gyro-kinetic code GS2 shows that all electrostatic micro-instabilities are stable in the negative magnetic shear region in the core, both with and without flow shear. Outside the ITB, in the region of positive magnetic shear and relatively weak flow shear, electrostatic micro-instabilities become unstable over a wide range of wave numbers. Flow shear reduces the linear growth rates of low-k modes but suppression of ITG modes is incomplete, which is consistent with the observed anomalous ion transport in this region; however, flow shear has little impact on growth rates of high-k, electron-scale modes. With counter-NBI ITBs of greater radial extent form outside qmin due to the broader profile of E × B flow shear produced by the greater prompt fast-ion loss torque.

Shear thinning effects on blood flow in straight and curved tubes

NASA Astrophysics Data System (ADS)

Cherry, Erica M.; Eaton, John K.

2013-07-01

Simulations were performed to determine the magnitude and types of errors one can expect when approximating blood in large arteries as a Newtonian fluid, particularly in the presence of secondary flows. This was accomplished by running steady simulations of blood flow in straight and curved tubes using both Newtonian and shear-thinning viscosity models. In the shear-thinning simulations, the viscosity was modeled as a shear rate-dependent function fit to experimental data. Simulations in straight tubes were modeled after physiologically relevant arterial flows, and flow parameters for the curved tube simulations were chosen to examine a variety of secondary flow strengths. The diameters ranged from 1 mm to 10 mm and the Reynolds numbers from 24 to 1500. Pressure and velocity data are reported for all simulations. In the straight tube simulations, the shear-thinning flows had flattened velocity profiles and higher pressure gradients compared to the Newtonian simulations. In the curved tube flows, the shear-thinning simulations tended to have blunted axial velocity profiles, decreased secondary flow strengths, and decreased axial vorticity compared to the Newtonian simulations. The cross-sectionally averaged pressure drops in the curved tubes were higher in the shear-thinning flows at low Reynolds number but lower at high Reynolds number. The maximum deviation in secondary flow magnitude averaged over the cross sectional area was 19% of the maximum secondary flow and the maximum deviation in axial vorticity was 25% of the maximum vorticity.

On the Kaolinite Floc Size at the Steady State of Flocculation in a Turbulent Flow

PubMed Central

Zhu, Zhongfan; Wang, Hongrui; Yu, Jingshan; Dou, Jie

2016-01-01

The flocculation of cohesive fine-grained sediment plays an important role in the transport characteristics of pollutants and nutrients absorbed on the surface of sediment in estuarine and coastal waters through the complex processes of sediment transport, deposition, resuspension and consolidation. Many laboratory experiments have been carried out to investigate the influence of different flow shear conditions on the floc size at the steady state of flocculation in the shear flow. Most of these experiments reported that the floc size decreases with increasing shear stresses and used a power law to express this dependence. In this study, we performed a Couette-flow experiment to measure the size of the kaolinite floc through sampling observation and an image analysis system at the steady state of flocculation under six flow shear conditions. The results show that the negative correlation of the floc size on the flow shear occurs only at high shear conditions, whereas at low shear conditions, the floc size increases with increasing turbulent shear stresses regardless of electrolyte conditions. Increasing electrolyte conditions and the initial particle concentration could lead to a larger steady-state floc size. PMID:26901652

On the Kaolinite Floc Size at the Steady State of Flocculation in a Turbulent Flow.

PubMed

Zhu, Zhongfan; Wang, Hongrui; Yu, Jingshan; Dou, Jie

2016-01-01

The flocculation of cohesive fine-grained sediment plays an important role in the transport characteristics of pollutants and nutrients absorbed on the surface of sediment in estuarine and coastal waters through the complex processes of sediment transport, deposition, resuspension and consolidation. Many laboratory experiments have been carried out to investigate the influence of different flow shear conditions on the floc size at the steady state of flocculation in the shear flow. Most of these experiments reported that the floc size decreases with increasing shear stresses and used a power law to express this dependence. In this study, we performed a Couette-flow experiment to measure the size of the kaolinite floc through sampling observation and an image analysis system at the steady state of flocculation under six flow shear conditions. The results show that the negative correlation of the floc size on the flow shear occurs only at high shear conditions, whereas at low shear conditions, the floc size increases with increasing turbulent shear stresses regardless of electrolyte conditions. Increasing electrolyte conditions and the initial particle concentration could lead to a larger steady-state floc size.

Applicability of Channel flow as an extrusion mechanism of the Higher Himalayan Shear Zone from Sutlej, Zanskar, Dhauliganga and Goriganga Sections, Indian Himalaya

NASA Astrophysics Data System (ADS)

Mukherjee, Soumyajit

2010-05-01

Applicability of Channel flow as an extrusion mechanism of the Higher Himalayan Shear Zone from Sutlej, Zanskar, Dhauliganga and Goriganga Sections, Indian Himalaya Soumyajit Mukherjee Department of Earth Sciences, Indian Institute of Technology Bombay Powai, Mumbai- 400076, INDIA, e-mail: soumyajitm@gmail.com Mukherjee & Koyi (1,2) evaluated the applicability of channel flow extrusion of the Higher Himalayan Shear Zone (HHSZ) in the Zanskar and the Sutlej sections based on field- and micro-structural studies, analytical- and analog models. Further work on the Dhauliganga and the Goriganga sections of the HHSZ reveal complicated structural geology that is untenable to explain simply in terms of channel flow. For example, in the former section, flexure slip folds exist in a zone spatially separated from the upper strand of the South Tibetan Detachment System (STDSU). On the other hand, in the later section, an STDSU- in the sense of Mukherjee and Koyi (1)- is absent. Instead, a steep extensional shear zone with northeasterly dipping shear plane cuts the pre-existing shear fabrics throughout the HHSZ. However, the following common structural features in the HHSZ were observed in these sections. (1) S-C fabrics are the most ubiquitous ductile shear sense indicators in field. (2) Brittle shearing along the preexisting ductile primary shear planes in a top-to-SW sense. (3) Less ubiquitous ductile compressional shearing in the upper part of the shear zone including the STDSU. (4) A phase of local brittle-ductile extension throughout the shear zone as revealed by boudins of various morphologies. (5) The shear zone is divisible into a southern non-migmatitic and a northern migmatitic zone. No special structural dissimilarity is observed across this lithological boundary. Keywords: Channel flow, Extrusion, Higher Himalaya, Structural Geology, Shear zone, Deformation References 1. Mukherjee S, Koyi HA (in press) Higher Himalayan Shear Zone, Sutlej section: structural geology and extrusion mechanism by various combinations of simple shear, pure shear and channel flow in shifting modes. International Journal of Earth Sciences. 2. Mukherjee S, Koyi HA (in press) Higher Himalayan Shear Zone, Zanskar Indian Himalaya: microstructural studies and extrusion mechanism by a combination of simple shear and channel flow. International Journal of Earth Sciences.

Non-Darcian flow of shear-thinning fluids through packed beads: Experiments and predictions using Forchheimer's law and Ergun's equation

NASA Astrophysics Data System (ADS)

Rodríguez de Castro, Antonio; Radilla, Giovanni

2017-02-01

The flow of shear-thinning fluids through unconsolidated porous media is present in a number of important industrial applications such as soil depollution, Enhanced Oil Recovery or filtration of polymeric liquids. Therefore, predicting the pressure drop-flow rate relationship in model porous media has been the scope of major research efforts during the last decades. Although the flow of Newtonian fluids through packs of spherical particles is well understood in most cases, much less is known regarding the flow of shear-thinning fluids as high molecular weight polymer aqueous solutions. In particular, the experimental data for the non-Darcian flow of shear-thinning fluids are scarce and so are the current approaches for their prediction. Given the relevance of non-Darcian shear-thinning flow, the scope of this work is to perform an experimental study to systematically evaluate the effects of fluid shear rheology on the flow rate-pressure drop relationships for the non-Darcian flow through different packs of glass spheres. To do so, xanthan gum aqueous solutions with different polymer concentrations are injected through four packs of glass spheres with uniform size under Darcian and inertial flow regimes. A total of 1560 experimental data are then compared with predictions coming from different methods based on the extension of widely used Ergun's equation and Forchheimer's law to the case of shear thinning fluids, determining the accuracy of these predictions. The use of a proper definition for Reynolds number and a realistic model to represent the rheology of the injected fluids results in the porous media are shown to be key aspects to successfully predict pressure drop-flow rate relationships for the inertial shear-thinning flow in packed beads.

Coronal Jet Collimation by Nonlinear Induced Flows

NASA Astrophysics Data System (ADS)

Vasheghani Farahani, S.; Hejazi, S. M.

2017-08-01

Our objective is to study the collimation of solar jets by nonlinear forces corresponding to torsional Alfvén waves together with external forces. We consider a straight, initially non-rotating, untwisted magnetic cylinder embedded in a plasma with a straight magnetic field, where a shear between the internal and external flows exists. By implementing magnetohydrodynamic theory and taking into account the second-order thin flux tube approximation, the balance between the internal nonlinear forces is visualized. The nonlinear differential equation containing the ponderomotive, magnetic tension, and centrifugal forces in the presence of the shear flow is obtained. The solution presents the scale of influence of the propagating torsional Alfvén wave on compressive perturbations. Explicit expressions for the compressive perturbations caused by the forces connected to the torsional Alfvén wave show that, in the presence of a shear flow, the magnetic tension and centrifugal forces do not cancel each other’s effects as they did in its absence. This shear flow plays in favor of the magnetic tension force, resulting in a more efficient collimation. Regarding the ponderomotive force, the shear flow has no effect. The phase relations highlight the interplay of the shear flow and the plasma-β. As the shear flow and plasma-β increase, compressive perturbation amplitudes emerge. We conclude that the jet collimation due to the torsional Alfvén wave highly depends on the location of the jet. The shear flow tightens the collimation as the jet elevates up to the solar corona.

Subsonic and Supersonic shear flows in laser driven high-energy-density plasmas

NASA Astrophysics Data System (ADS)

Harding, E. C.; Drake, R. P.; Gillespie, R. S.; Grosskopf, M. J.; Kuranz, C. C.; Visco, A.; Ditmar, J. R.; Aglitskiy, Y.; Weaver, J. L.; Velikovich, A. L.; Hurricane, O. A.; Hansen, J. F.; Remington, B. A.; Robey, H. F.; Bono, M. J.; Plewa, T.

2009-05-01

Shear flows arise in many high-energy-density (HED) and astrophysical systems, yet few laboratory experiments have been carried out to study their evolution in these extreme environments. Fundamentally, shear flows can initiate mixing via the Kelvin-Helmholtz (KH) instability and may eventually drive a transition to turbulence. We present two dedicated shear flow experiments that created subsonic and supersonic shear layers in HED plasmas. In the subsonic case the Omega laser was used to drive a shock wave along a rippled plastic interface, which subsequently rolled-upped into large KH vortices. In the supersonic shear experiment the Nike laser was used to drive Al plasma across a low-density foam surface also seeded with a ripple. Unlike the subsonic case, detached shocks developed around the ripples in response to the supersonic Al flow.

Effects of fracture surface roughness and shear displacement on geometrical and hydraulic properties of three-dimensional crossed rock fracture models

NASA Astrophysics Data System (ADS)

Huang, Na; Liu, Richeng; Jiang, Yujing; Li, Bo; Yu, Liyuan

2018-03-01

While shear-flow behavior through fractured media has been so far studied at single fracture scale, a numerical analysis of the shear effect on the hydraulic response of 3D crossed fracture model is presented. The analysis was based on a series of crossed fracture models, in which the effects of fracture surface roughness and shear displacement were considered. The rough fracture surfaces were generated using the modified successive random additions (SRA) algorithm. The shear displacement was applied on one fracture, and at the same time another fracture shifted along with the upper and lower surfaces of the sheared fracture. The simulation results reveal the development and variation of preferential flow paths through the model during the shear, accompanied by the change of the flow rate ratios between two flow planes at the outlet boundary. The average contact area accounts for approximately 5-27% of the fracture planes during shear, but the actual calculated flow area is about 38-55% of the fracture planes, which is much smaller than the noncontact area. The equivalent permeability will either increase or decrease as shear displacement increases from 0 to 4 mm, depending on the aperture distribution of intersection part between two fractures. When the shear displacement continuously increases by up to 20 mm, the equivalent permeability increases sharply first, and then keeps increasing with a lower gradient. The equivalent permeability of rough fractured model is about 26-80% of that calculated from the parallel plate model, and the equivalent permeability in the direction perpendicular to shear direction is approximately 1.31-3.67 times larger than that in the direction parallel to shear direction. These results can provide a fundamental understanding of fluid flow through crossed fracture model under shear.

Multifractal spectra in shear flows

NASA Technical Reports Server (NTRS)

Keefe, L. R.; Deane, Anil E.

1989-01-01

Numerical simulations of three-dimensional homogeneous shear flow and fully developed channel flow, are used to calculate the associated multifractal spectra of the energy dissipation field. Only weak parameterization of the results with the nondimensional shear is found, and this only if the flow has reached its asymptotic development state. Multifractal spectra of these flows coincide with those from experiments only at the range alpha less than 1.

Stability of surface plastic flow in large strain deformation of metals

NASA Astrophysics Data System (ADS)

Viswanathan, Koushik; Udapa, Anirduh; Sagapuram, Dinakar; Mann, James; Chandrasekar, Srinivasan

We examine large-strain unconstrained simple shear deformation in metals using a model two-dimensional cutting system and high-speed in situ imaging. The nature of the deformation mode is shown to be a function of the initial microstructure state of the metal and the deformation geometry. For annealed metals, which exhibit large ductility and strain hardening capacity, the commonly assumed laminar flow mode is inherently unstable. Instead, the imposed shear is accommodated by a highly rotational flow-sinuous flow-with vortex-like components and large-amplitude folding on the mesoscale. Sinuous flow is triggered by a plastic instability on the material surface ahead of the primary region of shear. On the other hand, when the material is extensively strain-hardened prior to shear, laminar flow again becomes unstable giving way to shear banding. The existence of these flow modes is established by stability analysis of laminar flow. The role of the initial microstructure state in determining the change in stability from laminar to sinuous / shear-banded flows in metals is elucidated. The implications for cutting, forming and wear processes for metals, and to surface plasticity phenomena such as mechanochemical Rehbinder effects are discussed.

Parasitic momentum flux in the tokamak core

NASA Astrophysics Data System (ADS)

Stoltzfus-Dueck, T.

2017-10-01

Tokamak plasmas rotate spontaneously without applied torque. This intrinsic rotation is important for future low-torque devices such as ITER, since rotation stabilizes certain instabilities. In the mid-radius `gradient region,' which reaches from the sawtooth inversion radius out to the pedestal top, intrinsic rotation profiles may be either flat or hollow, and can transition suddenly between these two states, an unexplained phenomenon referred to as rotation reversal. Theoretical efforts to explain the mid-radius rotation shear have largely focused on quasilinear models, in which the phase relationships of some selected instability result in a nondiffusive momentum flux (``residual stress''). In contrast, the present work demonstrates the existence of a robust, fully nonlinear symmetry-breaking momentum flux that follows from the free-energy flow in phase space and does not depend on any assumed linear eigenmode structure. The physical origin is an often-neglected portion of the radial ExB drift, which is shown to drive a symmetry-breaking outward flux of co-current momentum whenever free energy is transferred from the electrostatic potential to ion parallel flows. The fully nonlinear derivation relies only on conservation properties and symmetry, thus retaining the important contribution of damped modes. The resulting rotation peaking is counter-current and scales as temperature over plasma current. As first demonstrated by Landau, this free-energy transfer (thus also the corresponding residual stress) becomes inactive when frequencies are much higher than the ion transit frequency, which allows sudden transitions between hollow and flat profiles. Simple estimates suggest that this mechanism may be consistent with experimental observations. This work was funded in part by the Max-Planck/Princeton Center for Plasma Physics and in part by the U.S. Dept. of Energy, Office of Science, Contract No. DE-AC02-09CH11466.

A multi-component parallel-plate flow chamber system for studying the effect of exercise-induced wall shear stress on endothelial cells.

PubMed

Wang, Yan-Xia; Xiang, Cheng; Liu, Bo; Zhu, Yong; Luan, Yong; Liu, Shu-Tian; Qin, Kai-Rong

2016-12-28

In vivo studies have demonstrated that reasonable exercise training can improve endothelial function. To confirm the key role of wall shear stress induced by exercise on endothelial cells, and to understand how wall shear stress affects the structure and the function of endothelial cells, it is crucial to design and fabricate an in vitro multi-component parallel-plate flow chamber system which can closely replicate exercise-induced wall shear stress waveforms in artery. The in vivo wall shear stress waveforms from the common carotid artery of a healthy volunteer in resting and immediately after 30 min acute aerobic cycling exercise were first calculated by measuring the inner diameter and the center-line blood flow velocity with a color Doppler ultrasound. According to the above in vivo wall shear stress waveforms, we designed and fabricated a parallel-plate flow chamber system with appropriate components based on a lumped parameter hemodynamics model. To validate the feasibility of this system, human umbilical vein endothelial cells (HUVECs) line were cultured within the parallel-plate flow chamber under abovementioned two types of wall shear stress waveforms and the intracellular actin microfilaments and nitric oxide (NO) production level were evaluated using fluorescence microscope. Our results show that the trends of resting and exercise-induced wall shear stress waveforms, especially the maximal, minimal and mean wall shear stress as well as oscillatory shear index, generated by the parallel-plate flow chamber system are similar to those acquired from the common carotid artery. In addition, the cellular experiments demonstrate that the actin microfilaments and the production of NO within cells exposed to the two different wall shear stress waveforms exhibit different dynamic behaviors; there are larger numbers of actin microfilaments and higher level NO in cells exposed in exercise-induced wall shear stress condition than resting wall shear stress condition. The parallel-plate flow chamber system can well reproduce wall shear stress waveforms acquired from the common carotid artery in resting and immediately after exercise states. Furthermore, it can be used for studying the endothelial cells responses under resting and exercise-induced wall shear stress environments in vitro.

Toroidal equilibrium states with reversed magnetic shear and parallel flow in connection with the formation of Internal Transport Barriers

NASA Astrophysics Data System (ADS)

Kuiroukidis, Ap.; Throumoulopoulos, G. N.

2015-08-01

We construct nonlinear toroidal equilibria of fixed diverted boundary shaping with reversed magnetic shear and flows parallel to the magnetic field. The equilibria have hole-like current density and the reversed magnetic shear increases as the equilibrium nonlinearity becomes stronger. Also, application of a sufficient condition for linear stability implies that the stability is improved as the equilibrium nonlinearity correlated to the reversed magnetic shear gets stronger with a weaker stabilizing contribution from the flow. These results indicate synergetic stabilizing effects of reversed magnetic shear, equilibrium nonlinearity and flow in the establishment of Internal Transport Barriers (ITBs).

Measurement of the Shear Lift Force on a Bubble in a Channel Flow

NASA Technical Reports Server (NTRS)

Nahra, Henry K.; Motil, Brian; Skor, Mark

2005-01-01

Two-phase flow systems play vital roles in the design of some current and anticipated space applications of two-phase systems which include: thermal management systems, transfer line flow in cryogenic storage, space nuclear power facilities, design and operation of thermal bus, life support systems, propulsion systems, In Situ Resource Utilization (ISRU), and space processes for pharmaceutical applications. The design of two-phase flow systems for space applications requires a clear knowledge of the behaviors of the dispersed phase (bubble), its interaction with the continuous phase (liquid) and its effect on heat and mass transfer processes, The need to understand the bubble generation process arises from the fact that for all space applications, the size and distribution of bubbles are extremely crucial for heat and mass transfer control. One important force in two-phase flow systems is the lift force on a bubble or particle in a liquid shear flow. The shear lift is usually overwhelmed by buoyancy in normal gravity, but it becomes an important force in reduced gravity. Since the liquid flow is usually sheared because of the confining wall, the trajectories of bubbles and particles injected into the liquid flow are affected by the shear lift in reduced gravity. A series of experiments are performed to investigate the lift force on a bubble in a liquid shear flow and its effect on the detachment of a bubble from a wall under low gravity conditions. Experiments are executed in a Poiseuille flow in a channel. An air-water system is used in these experiments that are performed in the 2.2 second drop tower. A bubble is injected into the shear flow from a small injector and the shear lift is measured while the bubble is held stationary relative to the fluid. The trajectory of the bubble prior, during and after its detachment from the injector is investigated. The measured shear lift force is calculated from the trajectory of the bubble at the detachment point. These values for the shear lift are then compared with the theoretical predictions from various published works on shear lift in the open literature, which include asymptotic solutions at low bubble Reynolds number, potential flow predictions and numerical studies that deal with intermediate bubble Reynolds numbers.

Combinative application of pH-zone-refining and conventional high-speed counter-current chromatography for preparative separation of caged polyprenylated xanthones from gamboge.

PubMed

Xu, Min; Fu, Wenwei; Zhang, Baojun; Tan, Hongsheng; Xiu, Yanfeng; Xu, Hongxi

2016-02-01

An efficient method for the preparative separation of four structurally similar caged xanthones from the crude extracts of gamboge was established, which involves the combination of pH-zone-refining counter-current chromatography and conventional high-speed counter-current chromatography for the first time. pH-zone-refining counter-current chromatography was performed with the solvent system composed of n-hexane/ethyl acetate/methanol/water (7:3:8:2, v/v/v/v), where 0.1% trifluoroacetic acid was added to the upper organic stationary phase as a retainer and 0.03% triethylamine was added to the aqueous mobile phase as an eluter. From 3.157 g of the crude extract, 1.134 g of gambogic acid, 180.5 mg of gambogenic acid and 572.9 mg of a mixture of two other caged polyprenylated xanthones were obtained. The mixture was further separated by conventional high-speed counter-current chromatography with a solvent system composed of n-hexane/ethyl acetate/methanol/water (5:5:10:5, v/v/v/v) and n-hexane/methyl tert-butyl ether/acetonitrile/water (8:2:6:4,v/v/v/v), yielding 11.6 mg of isogambogenic acid and 10.4 mg of β-morellic acid from 218.0 mg of the mixture, respectively. The purities of all four of the compounds were over 95%, as determined by high-performance liquid chromatography, and the chemical structures of the four compounds were confirmed by electrospray ionization mass spectrometry and NMR spectroscopy. The combinative application of pH-zone-refining counter-current chromatography and conventional high-speed counter-current chromatography shows great advantages in isolating and enriching the caged polyprenylated xanthones. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Fluctuation-induced shear flow and energy transfer in plasma interchange turbulence

DOE Office of Scientific and Technical Information (OSTI.GOV)

Li, B.; Plasma Science and Fusion Center, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139; Sun, C. K.

2015-11-15

Fluctuation-induced E × B shear flow and energy transfer for plasma interchange turbulence are examined in a flux-driven system with both closed and open magnetic field lines. The nonlinear evolution of interchange turbulence shows the presence of two confinement regimes characterized by low and high E × B flow shear. In the first regime, the large-scale turbulent convection is dominant and the mean E × B shear flow is at a relatively low level. By increasing the heat flux above a certain threshold, the increased turbulent intensity gives rise to the transfer of energy from fluctuations to mean E ×more » B flows. As a result, a transition to the second regime occurs, in which a strong mean E × B shear flow is generated.« less

The importance of flow history in mixed shear and extensional flows

NASA Astrophysics Data System (ADS)

Wagner, Caroline; McKinley, Gareth

2015-11-01

Many complex fluid flows of experimental and academic interest exhibit mixed kinematics with regions of shear and elongation. Examples include flows through planar hyperbolic contractions in microfluidic devices and through porous media or geometric arrays. Through the introduction of a ``flow-type parameter'' α which varies between 0 in pure shear and 1 in pure elongation, the local velocity fields of all such mixed flows can be concisely characterized. It is tempting to then consider the local stress field and interpret the local state of stress in a complex fluid in terms of shearing or extensional material functions. However, the material response of such fluids exhibit a fading memory of the entire deformation history. We consider a dilute solution of Hookean dumbbells and solve the Oldroyd-B model to obtain analytic expressions for the entire stress field in any arbitrary mixed flow of constant strain rate and flow-type parameter α. We then consider a more complex flow for which the shear rate is constant but the flow-type parameter α varies periodically in time (reminiscent of flow through a periodic array or through repeated contractions and expansions). We show that the flow history and kinematic sequencing (in terms of whether the flow was initialized as shearing or extensional) is extremely important in determining the ensuing stress field and rate of dissipated energy in the flow, and can only be ignored in the limit of infinitely slow flow variations.

Anisotropic shear stress patterns predict the orientation of convergent tissue movements in the embryonic heart

PubMed Central

2017-01-01

Myocardial contractility and blood flow provide essential mechanical cues for the morphogenesis of the heart. In general, endothelial cells change their migratory behavior in response to shear stress patterns, according to flow directionality. Here, we assessed the impact of shear stress patterns and flow directionality on the behavior of endocardial cells, the specialized endothelial cells of the heart. At the early stages of zebrafish heart valve formation, we show that endocardial cells are converging to the valve-forming area and that this behavior depends upon mechanical forces. Quantitative live imaging and mathematical modeling allow us to correlate this tissue convergence with the underlying flow forces. We predict that tissue convergence is associated with the direction of the mean wall shear stress and of the gradient of harmonic phase-averaged shear stresses, which surprisingly do not match the overall direction of the flow. This contrasts with the usual role of flow directionality in vascular development and suggests that the full spatial and temporal complexity of the wall shear stress should be taken into account when studying endothelial cell responses to flow in vivo. PMID:29183943

Microstructural evolution of a model, shear-banding micellar solution during shear startup and cessation.

PubMed

López-Barrón, Carlos R; Gurnon, A Kate; Eberle, Aaron P R; Porcar, Lionel; Wagner, Norman J

2014-04-01

We present direct measurements of the evolution of the segmental-level microstructure of a stable shear-banding polymerlike micelle solution during flow startup and cessation in the plane of flow. These measurements provide a definitive, quantitative microstructural understanding of the stages observed during flow startup: an initial elastic response with limited alignment that yields with a large stress overshoot to a homogeneous flow with associated micellar alignment that persists for approximately three relaxation times. This transient is followed by a shear (kink) band formation with a flow-aligned low-viscosity band that exhibits shear-induced concentration fluctuations and coexists with a nearly isotropic band of homogenous, highly viscoelastic micellar solution. Stable, steady banding flow is achieved only after approximately two reptation times. Flow cessation from this shear-banded state is also found to be nontrivial, exhibiting an initial fast relaxation with only minor structural relaxation, followed by a slower relaxation of the aligned micellar fluid with the equilibrium fluid's characteristic relaxation time. These measurements resolve a controversy in the literature surrounding the mechanism of shear banding in entangled wormlike micelles and, by means of comparison to existing literature, provide further insights into the mechanisms driving shear-banding instabilities in related systems. The methods and instrumentation described should find broad use in exploring complex fluid rheology and testing microstructure-based constitutive equations.

Waste heat driven absorption refrigeration process and system

DOEpatents

Wilkinson, William H.

1982-01-01

Absorption cycle refrigeration processes and systems are provided which are driven by the sensible waste heat available from industrial processes and other sources. Systems are disclosed which provide a chilled water output which can be used for comfort conditioning or the like which utilize heat from sensible waste heat sources at temperatures of less than 170.degree. F. Countercurrent flow equipment is also provided to increase the efficiency of the systems and increase the utilization of available heat.

Wire-packed heat exchangers for dilution refrigerators.

PubMed

Polturak, E; Rappaport, M; Rosenbaum, R

1978-03-01

Very simple wire-packed step heat exchangers for dilution refrigerators are described. No sintering is used in fabrication. Flow impedances and thermal resistance between the liquid and the copper wires are low. A refrigerator with five wire-packed heat exchangers in addition to a countercurrent heat exchanger attains a temperature of 11.4 mK with a single mixing chamber and 6.1 mK with two mixing chambers. High cooling power is achieved at modest (3)He circulation rates.

Carbon wastewater treatment process

NASA Technical Reports Server (NTRS)

Humphrey, M. F.; Simmons, G. M.; Dowler, W. L.

1974-01-01

A new powdered-carbon treatment process is being developed for the elimination of the present problems, associated with the disposal of biologically active sewage waste solids, and with water reuse. This counter-current flow process produces an activated carbon, which is obtained from the pyrolysis of the sewage solids, and utilizes this material to remove the adulterating materials from the water. Additional advantages of the process are the elimination of odors, the removal of heavy metals, and the potential for energy conservation.

Separation and purification of hydrolyzable tannin from Geranium wilfordii Maxim by reversed-phase and normal-phase high-speed counter-current chromatography.

PubMed

Liu, Dan; Su, Zhiguo; Wang, Changhai; Gu, Ming; Xing, Siliang

2010-08-01

Three hydrolyzable tannins, geraniin, corilagin and gallic acid, main active components of Geranium wilfordii Maxim, have been separated and purified in one-step by both reversed-phase and normal-phase high-speed counter-current chromatography. Gallic acid, corilagin and geraniin were purified from 70% aqueous acetone extract of G. wilfordii Maxim with solvent system n-hexane-ethyl acetate-methanol-acetic acid-water (1:10:0.2:0.2:20) by reversed-phase high-speed counter-current chromatography at purities of 94.2, 91.0 and 91.3%, at yields of 89.3, 82.9 and 91.7%, respectively. Gallic acid, corilagin and geraniin were purified with solvent system n-hexane-ethyl acetate-methanol-acetic acid-water (0.2:10:2:1:5) by normal-phase high-speed counter-current chromatography at purities of 85.9, 92.2 and 87.6%, at yields of 87.4, 94.6 and 94.3%, respectively. It was successful for both reversed-phase and normal-phase high-speed counter-current chromatography to separate high-polarity of low-molecular-weight substances.

Coronal Jet Collimation by Nonlinear Induced Flows

DOE Office of Scientific and Technical Information (OSTI.GOV)

Vasheghani Farahani, S.; Hejazi, S. M.

2017-08-01

Our objective is to study the collimation of solar jets by nonlinear forces corresponding to torsional Alfvén waves together with external forces. We consider a straight, initially non-rotating, untwisted magnetic cylinder embedded in a plasma with a straight magnetic field, where a shear between the internal and external flows exists. By implementing magnetohydrodynamic theory and taking into account the second-order thin flux tube approximation, the balance between the internal nonlinear forces is visualized. The nonlinear differential equation containing the ponderomotive, magnetic tension, and centrifugal forces in the presence of the shear flow is obtained. The solution presents the scale ofmore » influence of the propagating torsional Alfvén wave on compressive perturbations. Explicit expressions for the compressive perturbations caused by the forces connected to the torsional Alfvén wave show that, in the presence of a shear flow, the magnetic tension and centrifugal forces do not cancel each other’s effects as they did in its absence. This shear flow plays in favor of the magnetic tension force, resulting in a more efficient collimation. Regarding the ponderomotive force, the shear flow has no effect. The phase relations highlight the interplay of the shear flow and the plasma- β . As the shear flow and plasma- β increase, compressive perturbation amplitudes emerge. We conclude that the jet collimation due to the torsional Alfvén wave highly depends on the location of the jet. The shear flow tightens the collimation as the jet elevates up to the solar corona.« less

The effects of surface tension on flooding in counter-current two-phase flow in an inclined tube

DOE Office of Scientific and Technical Information (OSTI.GOV)

Deendarlianto; Forschungszentrum Dresden-Rossendorf e.V., Institute of Safety Research, P.O. Box 510 119, D-01314 Dresden; Ousaka, Akiharu

2010-10-15

The purpose of the present study is to investigate the effects of surface tension on flooding phenomena in counter-current two-phase flow in an inclined tube. Previous studies by other researchers have shown that surface tension has a stabilizing effect on the falling liquid film under certain conditions and a destabilizing or unclear trend under other conditions. Experimental results are reported herein for air-water systems in which a surfactant has been added to vary the liquid surface tension without altering other liquid properties. The flooding section is a tube of 16 mm in inner diameter and 1.1 m length, inclined atmore » 30-60 from horizontal. The flooding mechanisms were observed by using two high-speed video cameras and by measuring the time variation of liquid hold-up along the test tube. The results show that effects of surface tension are significant. The gas velocity needed to induce flooding is lower for a lower surface tension. There was no upward motion of the air-water interfacial waves upon flooding occurrence, even for lower a surface tension. Observations on the liquid film behavior after flooding occurred suggest that the entrainment of liquid droplets plays an important role in the upward transport of liquid. Finally, an empirical correlation for flooding velocities is proposed that includes functional dependencies on surface tension and tube inclination. (author)« less

Preparation of the monomers of gingerols and 6-shogaol by flash high speed counter-current chromatography.

PubMed

Qiao, Qingliang; Du, Qizhen

2011-09-09

The flash high speed counter-current chromatographic (FHSCCC) separation of gingerols and 6-shogaol was performed on a HSCCC instrument equipped with a 1200-ml column (5 mm tubing i.d.) at a flow rate of 25 ml/min. The performance met the FHSCCC feature that the flow rate of mobile phase (ml) is equal to or greater than the square of the diameter of the column tubing (mm). The separation employed the upper phase of stationary phase of the n-hexane-ethyl acetate-methanol-water (3:2:2:3, v/v) as the stationary phase. A stepwise elution was performed by eluting with the lower phase of n-hexane-ethyl acetate-methanol-water (3:2:2:3, v/v) for first 90 min and the lower phase of the n-hexane-ethyl acetate-methanol-water (3:2:6:5, v/v) for the second 90 min. In each separation 5 g of the ethyl acetate extract of rhizomes of ginger was loaded, yielding 1.96 g of 6-gingerol (98.3%), 0.33 g of 8-gingerol (97.8%), 0.64 g of 6-shogaol (98.8%) and 0.57 g of 10-gingerol (98.2%). The separation can be expected to scale up to industrial separation. Copyright © 2010 Elsevier B.V. All rights reserved.

Experimental Reacting Hydrogen Shear Layer Data at High Subsonic Mach Number

NASA Technical Reports Server (NTRS)

Chang, C. T.; Marek, C. J.; Wey, C.; Wey, C. C.

1996-01-01

The flow in a planar shear layer of hydrogen reacting with hot air was measured with a two-component laser Doppler velocimeter (LDV) system, a schlieren system, and OH fluorescence imaging. It was compared with a similar air-to-air case without combustion. The high-speed stream's flow speed was about 390 m/s, or Mach 0.71, and the flow speed ratio was 0.34. The results showed that a shear layer with reaction grows faster than one without; both cases are within the range of data scatter presented by the established data base. The coupling between the streamwise and the cross-stream turbulence components inside the shear layers was low, and reaction only increased it slightly. However, the shear layer shifted laterally into the lower speed fuel stream, and a more organized pattern of Reynolds stress was present in the reaction shear layer, likely as a result of the formation of a larger scale structure associated with shear layer corrugation from heat release. Dynamic pressure measurements suggest that coherent flow perturbations existed inside the shear layer and that this flow became more chaotic as the flow advected downstream. Velocity and thermal variable values are listed in this report for a computational fluid dynamics (CFD) benchmark.

Electric-field-induced flow-aligning state in a nematic liquid crystal.

PubMed

Fatriansyah, Jaka Fajar; Orihara, Hiroshi

2015-04-01

The response of shear stress to a weak ac electric field as a probe is measured in a nematic liquid crystal under shear flow and dc electric fields. Two states with different responses are clearly observed when the dc electric field is changed at a constant shear rate: the flow aligning and non-flow aligning states. The director lies in the shear plane in the flow aligning state and out of the plane in the non-flow aligning state. Through application of dc electric field, the non-flow aligning state can be changed to the flow aligning state. In the transition from the flow aligning state to the non-flow aligning state, it is found that the response increases and the relaxation time becomes longer. Here, the experimental results in the flow aligning state are discussed on the basis of the Ericksen-Leslie theory.

Human endothelial cell responses to cardiovascular inspired pulsatile shear stress

NASA Astrophysics Data System (ADS)

Watson, Matthew; Baugh, Lauren; Black, Lauren, III; Kemmerling, Erica

2016-11-01

It is well established that hemodynamic shear stress regulates blood vessel structure and the development of vascular pathology. This process can be studied via in vitro models of endothelial cell responses to pulsatile shear stress. In this study, a macro-scale cone and plate viscometer was designed to mimic various shear stress waveforms found in the body and apply these stresses to human endothelial cells. The device was actuated by a PID-controlled DC gear-motor. Cells were exposed to 24 hours of pulsatile shear and then imaged and stained to track their morphology and secretions. These measurements were compared with control groups of cells exposed to constant shear and no shear. The results showed that flow pulsatility influenced levels of secreted proteins such as VE-cadherin and neuroregulin IHC. Cell morphology was also influenced by flow pulsatility; in general cells exposed to pulsatile shear stress developed a higher aspect ratio than cells exposed to no flow but a lower aspect ratio than cells exposed to steady flow.

Experimental investigations of the time and flow-direction responses of shear-stress-sensitive liquid crystal coatings

NASA Technical Reports Server (NTRS)

Reda, Daniel C.; Muratore, Joseph J., Jr.; Heineck, James T.

1993-01-01

Time and flow-direction responses of shearstress-sensitive liquid crystal coatings were explored experimentally. For the time-response experiments, coatings were exposed to transient, compressible flows created during the startup and off-design operation of an injector-driven supersonic wind tunnel. Flow transients were visualized with a focusing Schlieren system and recorded with a 1000 frame/sec color video camera. Liquid crystal responses to these changing-shear environments were then recorded with the same video system, documenting color-play response times equal to, or faster than, the time interval between sequential frames (i.e., 1 millisecond). For the flow-direction experiments, a planar test surface was exposed to equal-magnitude and known-direction surface shear stresses generated by both normal and tangential subsonic jet-impingement flows. Under shear, the sense of the angular displacement of the liquid crystal dispersed (reflected) spectrum was found to be a function of the instantaneous direction of the applied shear. This technique thus renders dynamic flow reversals or flow divergences visible over entire test surfaces at image recording rates up to 1 KHz. Extensions of the technique to visualize relatively small changes in surface shear stress direction appear feasible.

Etude hydromecanique d'une fracture en cisaillement sous contrainte normale constante

NASA Astrophysics Data System (ADS)

Lamontagne, Eric

This research study deals with the effects of shear direction and injection flow rate on the flow directional anisotropy for a given normal stress. It presents experimental works on hydromechanical shear behaviour of a fracture under constant normal stress conditions that permits the characterisation of the intrinsic hydraulic transmissivity in relation with the directional anisotropy of the roughness morphology on the fracture surfaces. Tests were performed on mortar replicas of a natural fracture so that the fracture roughness and void space geometry were kept the same for each test. The experimental work program was performed through direct shear tests on the fracture replicas in four shear directions under four constant normal stress levels. The application of the normal stress was followed by several injections of fluid under constant flow rate. Then, for each defined shear displacement, several injections of fluid were done at different flow rate but under constant flow rate. The test results show that: (1) for the whole shear tests, the global intrinsic transmissivity is included within an enveloping zone of about one order of size. The transmissivity curves within the enveloping zone has a particularity to increase about two orders of size in the first millimetre of shear displacement and subsequently stabilised rapidly; (2) the highest dilatancy do not correspond necessarily with the highest intrinsic transmissivity so that, the behaviour of the global intrinsic transmissivity is not directly proportional to the fracture dilatancy during shear; (3) after the peak shear stress, the divergence is more marked between the global intrinsic transmissivity curves at various flow rate; (4) after peak shear strength and the beginning of asperity degradation, the gradual passage to residual friction shear behaviour causes a directional flow anisotropy and a reorientation of the flow chenalisation direction sub perpendicularly to the shear direction; (5) the anisotropy is not to develop equally between the two sense in the perpendicular direction to shear direction. In order to characterise the dynamics of the flow pattern in the fracture, a statistical analysis of the surfaces morphology of the fracture and the casting of void space geometry were performed before and after shear. A statistical analysis of asperity heights, on the global scale of the fracture surfaces, permits to characterise the fracture morphology and put in evidence a large morphological structure on which are superposed smaller asperities of variable dimensions. This large dimension structure generate a higher level landing occupying more than half of the fracture area. The study of the surfaces morphology of the fracture, performed with the geostatistical mean asperity heights variogram by direction before shearing, show the presence of two entangled morphologic structure families (28 and 15 mm). This same study done after shearing shows that the asperity degradation seems associated with the reduction of the global intrinsic transmissivity of the fracture. Finally, the void spaces morphology evaluated by casting techniques, during the shear tests, has permitted to verify the contacts evolution with the increasing shear displacement and visualised flow chenalisation during fracture shearing.

Observation of Droplet Size Oscillations in a Two-Phase Fluid under Shear Flow

NASA Astrophysics Data System (ADS)

Courbin, Laurent; Panizza, Pascal; Salmon, Jean-Baptiste

2004-01-01

Experimental observations of droplet size sustained oscillations are reported in a two-phase flow between a lamellar and a sponge phase. Under shear flow, this system presents two different steady states made of monodisperse multilamellar droplets, separated by a shear-thinning transition. At low and high shear rates, the droplet size results from a balance between surface tension and viscous stress, whereas for intermediate shear rates it becomes a periodic function of time. A possible mechanism for such kinds of oscillations is discussed.

Flow-induced adhesion of shear-activated polymers to a substrate

NASA Astrophysics Data System (ADS)

Hoore, Masoud; Rack, Kathrin; Fedosov, Dmitry A.; Gompper, Gerhard

2018-02-01

Adhesion of polymers and proteins to substrates plays a crucial role in many technological applications and biological processes. A prominent example is the von Willebrand factor (VWF) protein, which is essential in blood clotting as it mediates adhesion of blood platelets to the site of injury at high shear rates. VWF is activated by flow and is able to bind efficiently to damaged vessel walls even under extreme flow-stress conditions; however, its adhesion is reversible when the flow strength is significantly reduced or the flow is ceased. Motivated by the properties and behavior of VWF in flow, we investigate adhesion of shear-activated polymers to a planar wall in flow and whether the adhesion is reversible under flow stasis. The main ingredients of the polymer model are cohesive inter-monomer interactions, a catch bond with the adhesive surface, and the shear activation/deactivation of polymer adhesion correlated with its stretching in flow. The cohesive interactions within the polymer maintain a globular conformation under low shear stresses and allow polymer stretching if a critical shear rate is exceeded, which is directly associated with its activation for adhesion. Our results show that polymer adhesion at high shear rates is significantly stabilized by catch bonds, while at the same time they also permit polymer dissociation from a surface at low or no flow stresses. In addition, the activation/deactivation mechanism for adhesion plays a crucial role in the reversibility of its adhesion. These observations help us better understand the adhesive behavior of VWF in flow and interpret its adhesion malfunctioning in VWF-related diseases.

Numerical study on tilting salt finger in a laminar shear flow

NASA Astrophysics Data System (ADS)

Zhang, Xianfei; Wang, Ling-ling; Lin, Cheng; Zhu, Hai; Zeng, Cheng

2018-02-01

Salt fingers as a mixing mechanism in the ocean have been investigated for several decades, together with a key issue being focused on their convective evolution and flux ratio variation. However, related studies on tilting fingers in the ocean produced by shear flow have been ignored by previous researchers. In this paper, a 2-D numerical model is presented to study the evolution of the double-diffusion salt finger in a two-layer thermohaline system with laminar shear flow. The model is divided into a steady-state solver and double-diffusion convection system, aimed to reveal the effect of shear flow on salt fingers and analyze the mechanism behind the shear and fingers. Several cases are conducted for Re = 0 ˜ 900 to study the evolution of salt fingers in a laminar shear flow and the variation of salt flux with Re. The results show that salt fingers exist and tilt in the presence of laminar shear flow. The mass transport in the vertical direction is weakened as the Reynolds number increases. An asymmetric structure of the salt finger is discovered and accounts for the morphological tilt and salt flux reduction.

Shear-modulated electroosmotic flow on a patterned charged surface.

PubMed

Wei, Hsien-Hung

2005-04-15

The effect of imposing shear flow on a charge-modulated electroosmotic flow is theoretically investigated. The flow structures exhibit either saddle points or closed streamlines, depending on the relative strength of an imposed shear to the applied electric field. The formation of closed streamlines could be advantageous for trapping nondiffusive particles at desired locations. Different time periodic alternating flows and their corresponding particle trajectories are also examined to assess strategies for creating efficient mixing.

Scaling of Counter-Current Imbibition Process in Low-Permeability Porous Media, TR-121

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kvoscek, A.R.; Zhou, D.; Jia, L.

2001-01-17

This project presents the recent work on imaging imbibition in low permeability porous media (diatomite) with X-ray completed tomography. The viscosity ratio between nonwetting and wetting fluids is varied over several orders of magnitude yielding different levels of imbibition performance. Also performed is mathematical analysis of counter-current imbibition processes and development of a modified scaling group incorporating the mobility ratio. This modified group is physically based and appears to improve scaling accuracy of countercurrent imbibition significantly.

An experimental investigation of a turbulent shear flow with separation, reverse flow, and reattachment

NASA Astrophysics Data System (ADS)

Ruderich, R.; Fernholz, H. H.

1986-02-01

Attention is given to the turbulent and disturbed flow over a bluff plate having a long splitter plate in its plane-of-symmetry, so that the flow separates at the sharp bevelled edge of the bluff plate, forms a free shear layer above the reverse flow region, and reattaches on the splitter plate over a narrow region that is curved in spanwise direction. Hot wire and pulsed wire anemometry were used to measure mean velocity, Reynolds shear stress and Reynolds normal stress distributions, and spectra and integral length-scales were measured to investigate the state and structure of the flow. Mean and fluctuating qualities showed a self-similar behavior in a short region upstream of the reattachment, as well as 'profile-similarity' in the separated shear layer and along the splitter plate downstream from reattachment. No flapping or reattaching shear layer was observed.

The production of premixed flame surface area in turbulent shear flow

NASA Technical Reports Server (NTRS)

Trouve, A.

1993-01-01

In the present work, we use three-dimensional Direct Numerical Simulation (DNS) of premixed flames in turbulent shear flow to characterize the effect of a mean shear motion on flame surface production. The shear is uniform in the unburnt gas, and simulations are performed for different values of the mean shear rate, S. The data base is then used to estimate and compare the different terms appearing in the Sigma-equation as a function of S. The analysis gives in particular the relative weights f the turbulent flow and mean flow components, a(sub T) and A(sub T), of the flame surface production term. This comparison indicates whether the dominant effects of a mean flow velocity gradient on flame surface area are implicit and scale with the modified turbulent flow parameters, kappa and epsilon, or explicit and scale directly with the rate of deformation.

Shear-induced orientational dynamics and spatial heterogeneity in suspensions of motile phytoplankton

PubMed Central

Barry, Michael T.; Rusconi, Roberto; Guasto, Jeffrey S.; Stocker, Roman

2015-01-01

Fluid flow, ubiquitous in natural and man-made environments, has the potential to profoundly impact the transport of microorganisms, including phytoplankton in aquatic habitats and bioreactors. Yet, the effect of ambient flow on the swimming behaviour of phytoplankton has remained poorly understood, largely owing to the difficulty of observing cell–flow interactions at the microscale. Here, we present microfluidic experiments where we tracked individual cells for four species of motile phytoplankton exposed to a spatially non-uniform fluid shear rate, characteristic of many flows in natural and artificial environments. We observed that medium-to-high mean shear rates (1–25 s−1) produce heterogeneous cell concentrations in the form of regions of accumulation and regions of depletion. The location of these regions relative to the flow depends on the cells' propulsion mechanism, body shape and flagellar arrangement, as captured by an effective aspect ratio. Species having a large effective aspect ratio accumulated in the high-shear regions, owing to shear-induced alignment of the swimming orientation with the fluid streamlines. Species having an effective aspect ratio close to unity exhibited little preferential accumulation at low-to-moderate flow rates, but strongly accumulated in the low-shear regions under high flow conditions, potentially owing to an active, behavioural response of cells to shear. These observations demonstrate that ambient fluid flow can strongly affect the motility and spatial distribution of phytoplankton and highlight the rich dynamics emerging from the interaction between motility, morphology and flow. PMID:26538558

Viscoelastic flow past mono- and bidisperse random arrays of cylinders: flow resistance, topology and normal stress distribution.

PubMed

De, S; Kuipers, J A M; Peters, E A J F; Padding, J T

2017-12-13

We investigate creeping viscoelastic fluid flow through two-dimensional porous media consisting of random arrangements of monodisperse and bidisperse cylinders, using our finite volume-immersed boundary method introduced in S. De, et al., J. Non-Newtonian Fluid Mech., 2016, 232, 67-76. The viscoelastic fluid is modeled with a FENE-P model. The simulations show an increased flow resistance with increase in flow rate, even though the bulk response of the fluid to shear flow is shear thinning. We show that if the square root of the permeability is chosen as the characteristic length scale in the determination of the dimensionless Deborah number (De), then all flow resistance curves collapse to a single master curve, irrespective of the pore geometry. Our study reveals how viscoelastic stresses and flow topologies (rotation, shear and extension) are distributed through the porous media, and how they evolve with increasing De. We correlate the local viscoelastic first normal stress differences with the local flow topology and show that the largest normal stress differences are located in shear flow dominated regions and not in extensional flow dominated regions at higher viscoelasticity. The study shows that normal stress differences in shear flow regions may play a crucial role in the increase of flow resistance for viscoelastic flow through such porous media.

Application of mean wall shear stress boundary condition to complex turbulent flows using a wall-modeled large eddy simulation

NASA Astrophysics Data System (ADS)

Cho, Minjeong; Lee, Jungil; Choi, Haecheon

2012-11-01

The mean wall shear stress boundary condition was successfully applied to turbulent channel and boundary flows using large eddy simulation without resolving near-wall region (see Lee, Cho & Choi in this book of abstracts). In the present study, we apply this boundary condition to more complex flows where flow separation and redeveloping flow exist. As a test problem, we consider flow over a backward-facing step at Reh = 22860 based on the step height. Turbulent boundary layer flow at the inlet (Reθ = 1050) is obtained using inflow generation technique by Lund et al. (1998) but with wall shear stress boundary condition. First, we prescribe the mean wall shear stress distribution obtained from DNS (Kim, 2011, Ph.D. Thesis, Stanford U.) as the boundary condition of present simulation. Here we give no-slip boundary condition at flow-reversal region. The present results are in good agreements with the flow statistics by DNS. Currently, a dynamic approach of obtaining mean wall shear stress based on the log-law is being applied to the flow having flow separation and its results will be shown in the presentation. Supported by the WCU and NRF programs.

[Simultaneous isolation and purification of gallic acid and brevifolincarboxylic acid from Polygonum capitatum by high-speed counter-current chromatography].

PubMed

Chen, Xinxia; Zhang, Liyan; Wan, Jinzhi; Liang, Bin; Xie, Yu

2010-08-01

To isolate and purify gallic acid and brevifolincarboxylic acid simultaneously by high-speed counter-current chromatography (HSCCC) from a crude extract of Polygonum capitatum. The biphasic solvent system composed of ethyl acetate-n-butanol-0.44% acetic acid (3:1:5) was used at a flow rate of 2.0 mL x min(-1), while the aqueous phase was selected as the mobile phase and the apparatus was rotated at 860 r x min(-1). The effluent was detected at 272 nm. 51.5 mg of gallic acid and 5.9 mg of brevifolincarboxylic acid were separated from 1.07 g of the crude extract with the purities of 99.7% and 97.5%, respectively, while brevifolincarboxylic acid was obtained firstly from the genus Polygonum. The structures of the compounds were identified by ultraviolet spectrometry (UV), infra-red spectrometry (IR), liquid chromatography/mass spectrometry (LC/MS), time-of-flight mass spectrometry( TOF-MS), 1H-nuclear magnetic resonance (NMR) and 13C-NMR. This method is feasible and rapid for isolation and purification of gallice acid and brevifolincarboxylil acid.

The impact of capillary backpressure on spontaneous counter-current imbibition in porous media

NASA Astrophysics Data System (ADS)

Foley, Amir Y.; Nooruddin, Hasan A.; Blunt, Martin J.

2017-09-01

We investigate the impact of capillary backpressure on spontaneous counter-current imbibition. For such displacements in strongly water-wet systems, the non-wetting phase is forced out through the inlet boundary as the wetting phase imbibes into the rock, creating a finite capillary backpressure. Under the assumption that capillary backpressure depends on the water saturation applied at the inlet boundary of the porous medium, its impact is determined using the continuum modelling approach by varying the imposed inlet saturation in the analytical solution. We present analytical solutions for the one-dimensional incompressible horizontal displacement of a non-wetting phase by a wetting phase in a porous medium. There exists an inlet saturation value above which any change in capillary backpressure has a negligible impact on the solutions. Above this threshold value, imbibition rates and front positions are largely invariant. A method for identifying this inlet saturation is proposed using an analytical procedure and we explore how varying multiphase flow properties affects the analytical solutions and this threshold saturation. We show the value of this analytical approach through the analysis of previously published experimental data.

Preparative separation of grape skin polyphenols by high-speed counter-current chromatography.

PubMed

Luo, Lanxin; Cui, Yan; Zhang, Shuting; Li, Lingxi; Li, Yuanyuan; Zhou, Peiyu; Sun, Baoshan

2016-12-01

To develop an efficient method for large preparation of various individual polyphenols from white grape skins (Fernão Pires; Vitis vinifera) by preparative high-speed counter-current chromatography (HSCCC) and preparative-HPLC, an optimized preparative HSCCC condition with two-phase solvent system composed of Hex-EtOAc-H2O (1:50:50, v/v) was used to separate grape skin polyphenols into various fractions. Both the tail-head and head-tail elution modes were used with a flow rate of 3.0ml/min and a rotary speed of 950rpm. Afterwards, a preparative-HPLC separation was applied to isolate individual polyphenols in each of the fractions from HSCCC. Total of 7 fractions (Fraction A to G) were obtained from grape skin extract by HSCCC. After preparative-HPLC isolation, fifteen individual compounds were obtained, most of which presented high yields and purity (all over 90%). The HSCCC method followed with preparative-HPLC appeared to be convenient and economical, constituting an efficient strategy for the isolation of grape skin polyphenols. Copyright © 2016 Elsevier Ltd. All rights reserved.

Experimental study on the signs of particulate structures formation in annular geometry of rapid granular shear flows

NASA Astrophysics Data System (ADS)

Ritvanen, J.; Jalali, P.

2009-06-01

Rapid granular shear flow is a classical example in granular materials which exhibits both fluid-like and solid-like behaviors. Another interesting feature of rapid granular shear flows is the formation of ordered structures upon shearing. Certain amount of granular material, with uniform size distribution, is required to be loaded in the container in order to shear it under stable conditions. This work concerns the experimental study of rapid granular shear flows in annular Couette geometry. The flow is induced by continuous rotation of the plate over the top of the granular bed in an annulus. The compressive pressure, driving torque, instantaneous bed height from three symmetric locations and rotational speed of the shearing plate are measured. The annulus has a capacity of up to 15 kg of spherical steel balls of 3 mm in diameter. Rapid shear flow experiments are performed in one compressive force and rotation rate. The sensitivity of fluctuations is then investigated by different means through monodisperse packing. In this work, we present the results of the experiments showing how the flow properties depend on the amount of loaded granular material which is varied by small amounts between different experiments. The flow can exist in stable (fixed behavior) and unstable (time-dependent behavior) regimes as a function of the loaded material. We present the characteristics of flow to detect the formation of any additional structured layer in the annulus. As a result, an evolution graph for the bed height has been obtained as material is gradually added. This graph shows how the bed height grows when material increases. Using these results, the structure inside the medium can be estimated at extreme stable and unstable conditions.

Shear-Modulated Electroosmotic Flow on a Patterned Charged Surface

NASA Astrophysics Data System (ADS)

Wei, Hsien-Hung

2004-11-01

The effect of imposing shear flow on a charge-modulated electroosmotic flow is theoretically investigated. The flow pattern can contain saddle points or closed streamlines, depending on the relative strength of an imposed shear to the applied electrical field. The formation of closed streamlines could be advantageous for trapping non-diffusive particles in desired locations. Different time periodic alternating flows and their corresponding particle trajectories are also examined for assessing strategies for creating efficient mixing.

Diffusive shunting of gases and other molecules in the renal vasculature: physiological and evolutionary significance.

PubMed

Ngo, Jennifer P; Ow, Connie P C; Gardiner, Bruce S; Kar, Saptarshi; Pearson, James T; Smith, David W; Evans, Roger G

2016-11-01

Countercurrent systems have evolved in a variety of biological systems that allow transfer of heat, gases, and solutes. For example, in the renal medulla, the countercurrent arrangement of vascular and tubular elements facilitates the trapping of urea and other solutes in the inner medulla, which in turn enables the formation of concentrated urine. Arteries and veins in the cortex are also arranged in a countercurrent fashion, as are descending and ascending vasa recta in the medulla. For countercurrent diffusion to occur, barriers to diffusion must be small. This appears to be characteristic of larger vessels in the renal cortex. There must also be gradients in the concentration of molecules between afferent and efferent vessels, with the transport of molecules possible in either direction. Such gradients exist for oxygen in both the cortex and medulla, but there is little evidence that large gradients exist for other molecules such as carbon dioxide, nitric oxide, superoxide, hydrogen sulfide, and ammonia. There is some experimental evidence for arterial-to-venous (AV) oxygen shunting. Mathematical models also provide evidence for oxygen shunting in both the cortex and medulla. However, the quantitative significance of AV oxygen shunting remains a matter of controversy. Thus, whereas the countercurrent arrangement of vasa recta in the medulla appears to have evolved as a consequence of the evolution of Henle's loop, the evolutionary significance of the intimate countercurrent arrangement of blood vessels in the renal cortex remains an enigma. Copyright © 2016 the American Physiological Society.

A numerical approach for assessing effects of shear on equivalent permeability and nonlinear flow characteristics of 2-D fracture networks

NASA Astrophysics Data System (ADS)

Liu, Richeng; Li, Bo; Jiang, Yujing; Yu, Liyuan

2018-01-01

Hydro-mechanical properties of rock fractures are core issues for many geoscience and geo-engineering practices. Previous experimental and numerical studies have revealed that shear processes could greatly enhance the permeability of single rock fractures, yet the shear effects on hydraulic properties of fractured rock masses have received little attention. In most previous fracture network models, single fractures are typically presumed to be formed by parallel plates and flow is presumed to obey the cubic law. However, related studies have suggested that the parallel plate model cannot realistically represent the surface characters of natural rock fractures, and the relationship between flow rate and pressure drop will no longer be linear at sufficiently large Reynolds numbers. In the present study, a numerical approach was established to assess the effects of shear on the hydraulic properties of 2-D discrete fracture networks (DFNs) in both linear and nonlinear regimes. DFNs considering fracture surface roughness and variation of aperture in space were generated using an originally developed code DFNGEN. Numerical simulations by solving Navier-Stokes equations were performed to simulate the fluid flow through these DFNs. A fracture that cuts through each model was sheared and by varying the shear and normal displacements, effects of shear on equivalent permeability and nonlinear flow characteristics of DFNs were estimated. The results show that the critical condition of quantifying the transition from a linear flow regime to a nonlinear flow regime is: 10-4 〈 J < 10-3, where J is the hydraulic gradient. When the fluid flow is in a linear regime (i.e., J < 10-4), the relative deviation of equivalent permeability induced by shear, δ2, is linearly correlated with J with small variations, while for fluid flow in the nonlinear regime (J 〉 10-3), δ2 is nonlinearly correlated with J. A shear process would reduce the equivalent permeability significantly in the orientation perpendicular to the sheared fracture as much as 53.86% when J = 1, shear displacement Ds = 7 mm, and normal displacement Dn = 1 mm. By fitting the calculated results, the mathematical expression for δ2 is established to help choose proper governing equations when solving fluid flow problems in fracture networks.

Measurements of Shear Lift Force on a Bubble in Channel Flow in Microgravity

NASA Technical Reports Server (NTRS)

Nahra, Henry K.; Motil, Brian J.; Skor, Mark

2003-01-01

Under microgravity conditions, the shear lift force acting on bubbles, droplets or solid particles in multiphase flows becomes important because under normal gravity, this hydrodynamic force is masked by buoyancy. This force plays an important role in furnishing the detachment process of bubbles in a setting where a bubble suspension is needed in microgravity. In this work, measurements of the shear lift force acting on a bubble in channel flow are performed. The shear lift force is deduced from the bubble kinematics using scaling and then compared with predictions from models in literature that address different asymptotic and numerical solutions. Basic trajectory calculations are then performed and the results are compared with experimental data of position of the bubble in the channel. A direct comparison of the lateral velocity of the bubbles is also made with the lateral velocity prediction from investigators, whose work addressed the shear lift on a sphere in different two-dimensional shear flows including Poiseuille flow.

Evolution of finite-amplitude localized vortices in planar homogeneous shear flows

NASA Astrophysics Data System (ADS)

Karp, Michael; Shukhman, Ilia G.; Cohen, Jacob

2017-02-01

An analytical-based method is utilized to follow the evolution of localized initially Gaussian disturbances in flows with homogeneous shear, in which the base velocity components are at most linear functions of the coordinates, including hyperbolic, elliptic, and simple shear. Coherent structures, including counterrotating vortex pairs (CVPs) and hairpin vortices, are formed for the cases where the streamlines of the base flow are open (hyperbolic and simple shear). For hyperbolic base flows, the dominance of shear over rotation leads to elongation of the localized disturbance along the outlet asymptote and formation of CVPs. For simple shear CVPs are formed from linear and nonlinear disturbances, whereas hairpins are observed only for highly nonlinear disturbances. For elliptic base flows CVPs, hairpins and vortex loops form initially, however they do not last and break into various vortical structures that spread in the spanwise direction. The effect of the disturbance's initial amplitude and orientation is examined and the optimal orientation achieving maximal growth is identified.

Porosity localizing instability in a compacting porous layer in a pure shear flow and the evolution of porosity band wavelength

NASA Astrophysics Data System (ADS)

Butler, S. L.

2010-09-01

A porosity localizing instability occurs in compacting porous media that are subjected to shear if the viscosity of the solid matrix decreases with porosity ( Stevenson, 1989). This instability may have significant consequences for melt transport in regions of partial melt in the mantle and may significantly modify the effective viscosity of the asthenosphere ( Kohlstedt and Holtzman, 2009). Most analyses of this instability have been carried out assuming an imposed simple shear flow (e.g., Spiegelman, 2003; Katz et al., 2006; Butler, 2009). Pure shear can be realized in laboratory experiments and studying the instability in a pure shear flow allows us to test the generality of some of the results derived for simple shear and the flow pattern for pure shear more easily separates the effects of deformation from rotation. Pure shear flows may approximate flows near the tops of mantle plumes near earth's surface and in magma chambers. In this study, we present linear theory and nonlinear numerical model results for a porosity and strain-rate weakening compacting porous layer subjected to pure shear and we investigate the effects of buoyancy-induced oscillations. The linear theory and numerical model will be shown to be in excellent agreement. We will show that melt bands grow at the same angles to the direction of maximum compression as in simple shear and that buoyancy-induced oscillations do not significantly inhibit the porosity localizing instability. In a pure shear flow, bands parallel to the direction of maximum compression increase exponentially in wavelength with time. However, buoyancy-induced oscillations are shown to inhibit this increase in wavelength. In a simple shear flow, bands increase in wavelength when they are in the orientation for growth of the porosity localizing instability. Because the amplitude spectrum is always dominated by bands in this orientation, band wavelengths increase with time throughout simple shear simulations until the wavelength becomes similar to one compaction length. Once the wavelength becomes similar to one compaction length, the growth of the amplitude of the band slows and shorter wavelength bands that are increasing in amplitude at a greater rate take over. This may provide a mechanism to explain the experimental observation that band spacing is controlled by the compaction length ( Kohlstedt and Holtzman, 2009).

Method of independently operating a group of stages within a diffusion cascade

DOEpatents

Benedict, Manson; Fruit, Allen J.; Levey, Horace B.

1976-06-08

1. A method of operating a group of the diffusion stages of a productive diffusion cascade with countercurrent flow, said group comprising a top and a bottom stage, which comprises isolating said group from said cascade, circulating the diffused gas produced in said top stage to the feed of said bottom stage while at the same time circulating the undiffused gas from said bottom stage to the feed of said top stage whereby major changes in

Coherent motion in excited free shear flows

NASA Technical Reports Server (NTRS)

Wygnanski, Israel J.; Petersen, Robert A.

1987-01-01

The application of the inviscid instability approach to externally excited turbulent free shear flows at high Reynolds numbers is explored. Attention is given to the cases of a small-deficit plane turbulent wake, a plane turbulent jet, an axisymmetric jet, the nonlinear evolution of instabilities in free shear flows, the concept of the 'preferred mode', vortex pairing in turbulent mixing layers, and experimental results for the control of free turbulent shear layers. The special features often attributed to pairing or to the preferred mode are found to be difficult to comprehend; the concept of feedback requires further substantiation in the case of incompressible flow.

Growth of viscoelastic wings and the reduction of particle mobility in a viscoelastic shear flow

NASA Astrophysics Data System (ADS)

Murch, William L.; Krishnan, Sreenath; Shaqfeh, Eric S. G.; Iaccarino, Gianluca

2017-10-01

The motion of a rigid spherical particle in a sheared polymeric fluid is studied via experiments and numerical simulations. We study particle mobility in highly elastic fluids, where the deformation due to the sphere's movement and the shear flow both result in significant stretching of the polymer. The shear flow is imposed in a plane perpendicular to the sphere's movement, resulting in regions of high polymer tension in the wake of the sphere that can extend well into the shear flow and gradient directions. We observe that these viscoelastic wake structures, resembling wings, are linked to an increase in the form drag, providing a mechanism for a dramatic decrease in the particle mobility.

Shear stress induced stimulation of mammalian cell metabolism

NASA Technical Reports Server (NTRS)

Mcintire, L. V.; Frangos, J. A.; Eskin, S. G.

1988-01-01

A flow apparatus was developed for the study of the metabolic response of anchorage dependent cells to a wide range of steady and pulsatile shear stresses under well controlled conditions. Human umbilical vein endothelial cell monolayers were subjected to steady shear stresses of up to 24 dynes/sq cm, and the production of prostacyclin was determined. The onset of flow led to a burst in prostacyclin production which decayed to a long term steady state rate (SSR). The SSR of cells exposed to flow was greater than the basal release level, and increased linearly with increasing shear stress. It is demonstrated that shear stresses in certain ranges may not be detrimental to mammalian cell metabolism. In fact, throughout the range of shear stresses studied, metabolite production is maximized by maximizing shear stress.

Computational analysis of integrated biosensing and shear flow in a microfluidic vascular model

NASA Astrophysics Data System (ADS)

Wong, Jeremy F.; Young, Edmond W. K.; Simmons, Craig A.

2017-11-01

Fluid flow and flow-induced shear stress are critical components of the vascular microenvironment commonly studied using microfluidic cell culture models. Microfluidic vascular models mimicking the physiological microenvironment also offer great potential for incorporating on-chip biomolecular detection. In spite of this potential, however, there are few examples of such functionality. Detection of biomolecules released by cells under flow-induced shear stress is a significant challenge due to severe sample dilution caused by the fluid flow used to generate the shear stress, frequently to the extent where the analyte is no longer detectable. In this work, we developed a computational model of a vascular microfluidic cell culture model that integrates physiological shear flow and on-chip monitoring of cell-secreted factors. Applicable to multilayer device configurations, the computational model was applied to a bilayer configuration, which has been used in numerous cell culture applications including vascular models. Guidelines were established that allow cells to be subjected to a wide range of physiological shear stress while ensuring optimal rapid transport of analyte to the biosensor surface and minimized biosensor response times. These guidelines therefore enable the development of microfluidic vascular models that integrate cell-secreted factor detection while addressing flow constraints imposed by physiological shear stress. Ultimately, this work will result in the addition of valuable functionality to microfluidic cell culture models that further fulfill their potential as labs-on-chips.

Exact coherent structures in an asymptotically reduced description of parallel shear flows

NASA Astrophysics Data System (ADS)

Beaume, Cédric; Knobloch, Edgar; Chini, Gregory P.; Julien, Keith

2015-02-01

A reduced description of shear flows motivated by the Reynolds number scaling of lower-branch exact coherent states in plane Couette flow (Wang J, Gibson J and Waleffe F 2007 Phys. Rev. Lett. 98 204501) is constructed. Exact time-independent nonlinear solutions of the reduced equations corresponding to both lower and upper branch states are found for a sinusoidal, body-forced shear flow. The lower branch solution is characterized by fluctuations that vary slowly along the critical layer while the upper branch solutions display a bimodal structure and are more strongly focused on the critical layer. The reduced equations provide a rational framework for investigations of subcritical spatiotemporal patterns in parallel shear flows.

Rivers in the sea - Can we quantify pigments in the Amazon and the Orinoco River plumes from space?

NASA Technical Reports Server (NTRS)

Muller-Karger, Frank E.; Walsh, John J.; Carder, Kendall L.; Zika, Rod G.

1989-01-01

Coastal Zone Color Scanner (CZCS) images of the western tropical Atlantic (1979-1982) were combined into monthly mean surface pigment fields. These suggest that Amazon River water flows along northeastern South America directly toward the Caribbean sea early in the year. After June, however, the North Brazil Current is shunted eastward, carrying a large fraction of Amazon water into the North Equatorial Countercurrent (NECC). This eastward flow causes diminished flow through the Caribbean, which permits northwestward dispersal of Orinoco River water due to local Ekman forcing. The Orinoco plume crosses the Caribbean, leading to seasonal variation in surface salinity near Puerto Rico. At least 50 percent of the pigment concentration estimated in these plumes seems due to viable phytoplankton.

Observation of improved and degraded confinement with driven flow on the LAPD

NASA Astrophysics Data System (ADS)

Schaffner, David

2012-10-01

External continuous control over azimuthal flow and flow shear has been achieved in a linear plasma device for the first time allowing for a careful study of the effect of flow shear on pressure-gradient-driven turbulence and transport in the edge of the Large Plasma Device (LAPD). The flow is controlled using biasable iris-like limiters situated axially between the cathode source and main plasma chamber. LAPD rotates spontaneously in the ion diamagnetic direction (IDD); positive limiter bias first reduces, then minimizes (producing a near-zero shear state), and finally reverses the flow into the electron diamagnetic direction (EDD). Degradation of particle confinement is observed in the minimum shearing state and reduction in turbulent particle flux is observed with increasing shearing in both flow directions. Near-complete suppression of turbulent particle flux is observed for shearing rates comparable to the turbulent autocorrelation rate measured in the minimum shear state. Turbulent flux suppression is dominated by amplitude reduction in low-frequency (>10kHz) density fluctuations and a reduction in the radial correlation length. An increase in fluctuations for the highest shearing states is observed with the emergence of a coherent mode which does not lead to net particle transport. Magnetic field is varied in order to explore whether and how field effects transport modification. Calculations of transport equations are used to predict density profiles given source and temperature profiles and can show the level of transport predicted to be necessary in order to produce the experimental density profiles observed. Finally, the variations of density fluctuations and radial correlation length are fit well with power-laws and compare favorably to simple models of shear suppression of transport.

Shear alters motility of Escherichia coli

NASA Astrophysics Data System (ADS)

Molaei, Mehdi; Jalali, Maryam; Sheng, Jian

2013-11-01

Understanding of locomotion of microorganisms in shear flows drew a wide range of interests in microbial related topics such as biological process including pathogenic infection and biophysical interactions like biofilm formation on engineering surfaces. We employed microfluidics and digital holography microscopy to study motility of E. coli in shear flows. We controlled the shear flow in three different shear rates: 0.28 s-1, 2.8 s-1, and 28 s-1 in a straight channel with the depth of 200 μm. Magnified holograms, recorded at 15 fps with a CCD camera over more than 20 minutes, are analyzed to obtain 3D swimming trajectories and subsequently used to extract shear responses of E.coli. Thousands of 3-D bacterial trajectories are tracked. The change of bacteria swimming characteristics including swimming velocity, reorientation, and dispersion coefficient are computed directly for individual trajectory and ensemble averaged over thousands of realizations. The results show that shear suppresses the bacterial dispersions in bulk but promote dispersions near the surface contrary to those in quiescent flow condition. Ongoing analyses are focusing to quantify effect of shear rates on tumbling frequency and reorientation of cell body, and its implication in locating the hydrodynamic mechanisms for shear enhanced angular scattering. NIH, NSF, GoMRI.

A master dynamic flow diagram for the shear thickening transition in micellar solutions.

PubMed

Bautista, F; Tepale, N; Fernández, V V A; Landázuri, G; Hernández, E; Macías, E R; Soltero, J F A; Escalante, J I; Manero, O; Puig, J E

2016-01-07

The shear thickening behavior of dilute micellar solutions of hexadecyltrimethylammonium-type surfactants with different counterions (tosylate, 3- and 4-fluorobenzoate, vinylbenzoate and salicylate) and of n-alkyltetradecylammonium bromide (CnTAB), with n = 14, 16 and 18, is examined here. These solutions undergo a shear thickening transition due to the formation of shear-induced structures (SISs) in the shear range studied. Here we report a relationship between the shear thickening intensity and the differences in the hydrophobicity of counterions according to the Hofmeister-like anion series, which leads to a master flow diagram. This master flow diagram is produced by plotting a normalized shear thickening intensity (Iη - 1)/(Imax - 1) versus CD/CD,max, where Iη is the shear-thickening intensity, defined as the largest viscosity obtained in the shear-thickening transition (STT) at a given surfactant concentration CD divided by the Newtonian viscosity η0, and Imax is the largest intensity value obtained in the STT at a surfactant concentration CD,max. The master flow diagram is built using several cetyltrimethylammonium-type surfactants with different counterions, according to a Hofmeister-like series, and by n-alkyltetradecylammonium bromide surfactants with different alkyl chain lengths.

ESTIMATION OF SHEAR STRESS WORKING ON SUBMERGED HOLLOW FIBRE MEMBRANE BY CFD METHOD IN MBRs

NASA Astrophysics Data System (ADS)

Zaw, Hlwan Moe; Li, Tairi; Nagaoka, Hiroshi

This study was conducted to evaluate shear stress working on submerged hollow fibre membrane by CFD (Computation Fluid Dynamics) method in MBRs. Shear stress on hollow fibre membrane caused by aeration was measured directly using a two-direction load sensor. The measurement of water-phase flow velocity was done also by using laser doppler velocimeter. It was confirmed that the shear stress was possible to be evaluated from the water-phase flow velocityby the result of comparison of time average shear stress actually measured with one hollow fibre membrane and the one calculated by the water-phase flow velocity. In the estimation of the water-phase flow velocity using the CFD method, time average water-phase flow velocity estimated by consideration of the fluid resistance of the membrane module nearly coincided with the measured values, and it was shown that it was possible to be estimated also within the membrane module. Moreover, the measured shear stress and drag force well coincided with the values calculated from the estimated water-phase flow velocity outside of membrane module and in the center of membrane module, and it was suggested that the shear stress on the hollow fibre membrane could be estimated by the CFD method in MBRs.

New concepts for Reynolds stress transport equation modeling of inhomogeneous flows

NASA Technical Reports Server (NTRS)

Perot, J. Blair; Moin, Parviz

1993-01-01

The ability to model turbulence near solid walls and other types of boundaries is important in predicting complex engineering flows. Most turbulence modeling has concentrated either on flows which are nearly homogeneous or isotropic, or on turbulent boundary layers. Boundary layer models usually rely very heavily on the presence of mean shear and the production of turbulence due to that mean shear. Most other turbulence models are based on the assumption of quasi-homogeneity. However, there are many situations of engineering interest which do not involve large shear rates and which are not quasi-homogeneous or isotropic. Shear-free turbulent boundary layers are the prototypical example of such flows, with practical situations being separation and reattachment, bluff body flow, high free-stream turbulence, and free surface flows. Although these situations are not as common as the variants of the flat plate turbulent boundary layer, they tend to be critical factors in complex engineering situations. The models developed are intended to extend classical quasi-homogeneous models into regions of large inhomogeneity. These models do not rely on the presence of mean shear or production, but are still applicable when those additional effects are included. Although the focus is on shear-free boundary layers as tests for these models, results for standard shearing boundary layers are also shown.

Selective excitation of tropical atmospheric waves in wave-CISK: The effect of vertical wind shear

NASA Technical Reports Server (NTRS)

Zhang, Minghua; Geller, Marvin A.

1994-01-01

The growth of waves and the generation of potential energy in wave-CISK require unstable waves to tilt with height oppositely to their direction of propagation. This makes the structures and instability properties of these waves very sensitive to the presence of vertical shear in the basic flow. Equatorial Kelvin and Rossby-gravity waves have opposite phase tilt with height to what they have in the stratosphere, and their growth is selectively favored by basic flows with westward vertical shear and eastward vertical shear, respectively. Similar calculations are also made for gravity waves and Rossby waves. It is shown that eastward vertical shear of the basic flow promotes CISK for westward propagating Rossby-gravity, Rossby, and gravity waves and suppresses CISK for eastward propagating Kelvin and gravity waves, while westward shear of the basic flow has the reverse effects.

Preparative isolation and purification of astaxanthin from the microalga Chlorococcum sp. by high-speed counter-current chromatography.

PubMed

Li, H B; Chen, F

2001-08-03

High-speed counter-current chromatography was applied to the isolation and purification of astaxanthin from microalgae. The crude astaxanthin was obtained by extraction with organic solvents after the astaxanthin esters were saponified. Preparative high-speed counter-current chromatography with a two-phase solvent system composed of n-hexane-ethyl acetate-ethanol-water (5:5:6.5:3, v/v) was successfully performed yielding astaxanthin at 97% purity from 250 mg of the crude extract in a one-step separation.

Ribbon phase in a phase-separated lyotropic lamellar-sponge mixture under shear flow

NASA Astrophysics Data System (ADS)

Cristobal, G.; Rouch, J.; Panizza, P.; Narayanan, T.

2001-07-01

We report the effect of shear flow on a phase-separated system composed of lyotropic lamellar (Lα) and sponge (L3) phases in a mixture of brine, surfactant, and cosurfactant. Optical microscopy, small-angle light, and x-ray scattering measurements are consistent with the existence of a steady state made of multilamellar ribbonlike structures aligned in the flow direction. At high shear rates, these ribbonlike structures become unstable and break up into monodisperse droplets resulting in a shear-thickening transition.

An analysis of the characteristics of rough bed turbulent shear stresses in an open channel

NASA Astrophysics Data System (ADS)

Keshavarzy, A.; Ball, J. E.

1997-06-01

Entrainment of sediment particles from channel beds into the channel flow is influenced by the characteristics of the flow turbulence which produces stochastic shear stress fluctuations at the bed. Recent studies of the structure of turbulent flow has recognized the importance of bursting processes as important mechanisms for the transfer of momentum into the laminar boundary layer. Of these processes, the sweep event has been recognized as the most important bursting event for entrainment of sediment particles as it imposes forces in the direction of the flow resulting in movement of particles by rolling, sliding and occasionally saltating. Similarly, the ejection event has been recognized as important for sediment transport since these events maintain the sediment particles in suspension. In this study, the characteristics of bursting processes and, in particular, the sweep event were investigated in a flume with a rough bed. The instantaneous velocity fluctuations of the flow were measured in two-dimensions using a small electromagnetic velocity meter and the turbulent shear stresses were determined from these velocity fluctuations. It was found that the shear stress applied to the sediment particles on the bed resulting from sweep events depends on the magnitude of the turbulent shear stress and its probability distribution. A statistical analysis of the experimental data was undertaken and it was found necessary to apply a Box-Cox transformation to transform the data into a normally distributed sample. This enabled determination of the mean shear stress, angle of action and standard error of estimate for sweep and ejection events. These instantaneous shear stresses were found to be greater than the mean flow shear stress and for the sweep event to be approximately 40 percent greater near the channel bed. Results from this analysis suggest that the critical shear stress determined from Shield's diagram is not sufficient to predict the initiation of motion due to its use of the temporal mean shear stress. It is suggested that initiation of particle motion, but not continuous motion, can occur earlier than suggested by Shield's diagram due to the higher shear stresses imposed on the particles by the stochastic shear stresses resulting from turbulence within the flow.

Modifications to intermittent turbulent structures by sheared flow in LAPD

NASA Astrophysics Data System (ADS)

Rossi, Giovanni; Schaffner, David; Carter, Troy; Guice, Danny; Bengtson, Roger

2012-10-01

Turbulence in the edge of the Large Plasma Device is generally observed to be intermittent with the production of filamentary structures. Density-enhancement events (called ``blobs'') are localized to the region radially outside the edge of the cathode source while density-depletion events (called ``holes'') are localized to the region radially inward. A flow-shear layer is also observed to be localized to this same spatial region. Control over the edge flow and shear in LAPD is now possible using a biasable limiter. Edge intermittency is observed to be strongly affected by variations in the edge flow, with intermittency (as measured by skewness of the fluctuation amplitude PDF) increasing with edge flow (in either direction) and reaching a minimum when spontaneous edge flow is zeroed-out using biasing. This trend is counter to the observed changes in turbulent particle flux, which peaks at low flow/shear. Two-dimensional cross-conditional averaging confirms the blobs to be detached filamentary structures with a clear dipolar potential structure and a geometry also dependent on the magnitude of sheared flow. More detailed measurements are made to connect the occurrence of these blobs to observed flow-driven coherent modes and their contribution to radial particle flux.

Influence of vibration on structure rheological properties of a highly concentrated suspension

NASA Astrophysics Data System (ADS)

Ouriev Uriev, Boris N.; Uriev, Naum B.

2005-08-01

The influence of mechanical vibration on the flow properties of a highly concentrated multiphase food system is explored in this work. An experimental set-up was designed and adapted to a conventional rotational rheometer with precise rheological characterization capability. A number of calibration tests were performed prior to fundamental experiments with a highly concentrated chocolate suspension. Also, the prediction of wall slippage in shear flow under vibration was evaluated. Analysis of the boundary conditions shows that no side effects such as wall slippage or the Taylor effect were present during the shear experiment under vibration. It was found that superposition of mechanical vibration and shear flow radically decreases the shear viscosity. Comparison between reference shear viscosities at specified shear rates and those measured under vibration shows considerable differences in flow properties. Conversion of the behaviour of the concentrated suspension from strongly shear-thinning to Newtonian flow is reported. Also, the appearance of vibration-induced dilatancy as a new phenomenon is described. It is suggested to relate such phenomena to the non-equilibrium between structure formation and disintegration under vibration and hydrodynamic forces of shear flow. The influence of vibration on structure formation can be well observed during measurement of the yield value of the chocolate suspension under vibration. Comparison with reference data shows how sensitive the structure of the concentrated suspension is to vibration in general. The effects and observations revealed provide a solid basis for further fundamental investigations of structure formation regularities in the flow of any highly concentrated system. The results also show the technological potential for non-conventional treatment of concentrated, multiphase systems.

Impact of E × B shear flow on low-n MHD instabilities.

PubMed

Chen, J G; Xu, X Q; Ma, C H; Xi, P W; Kong, D F; Lei, Y A

2017-05-01

Recently, the stationary high confinement operations with improved pedestal conditions have been achieved in DIII-D [K. H. Burrell et al. , Phys. Plasmas 23 , 056103 (2016)], accompanying the spontaneous transition from the coherent edge harmonic oscillation (EHO) to the broadband MHD turbulence state by reducing the neutral beam injection torque to zero. It is highly significant for the burning plasma devices such as ITER. Simulations about the effects of E  ×  B shear flow on the quiescent H-mode (QH-mode) are carried out using the three-field two-fluid model in the field-aligned coordinate under the BOUT++ framework. Using the shifted circular cross-section equilibriums including bootstrap current, the results demonstrate that the E  ×  B shear flow strongly destabilizes low-n peeling modes, which are mainly driven by the gradient of parallel current in peeling-dominant cases and are sensitive to the E r shear. Adopting the much more general shape of E  ×  B shear ([Formula: see text]) profiles, the linear and nonlinear BOUT++ simulations show qualitative consistence with the experiments. The stronger shear flow shifts the most unstable mode to lower-n and narrows the mode spectrum. At the meantime, the nonlinear simulations of the QH-mode indicate that the shear flow in both co- and counter directions of diamagnetic flow has some similar effects. The nonlinear mode interaction is enhanced during the mode amplitude saturation phase. These results reveal that the fundamental physics mechanism of the QH-mode may be shear flow and are significant for understanding the mechanism of EHO and QH-mode.

Impact of E × B shear flow on low-n MHD instabilities

NASA Astrophysics Data System (ADS)

Chen, J. G.; Xu, X. Q.; Ma, C. H.; Xi, P. W.; Kong, D. F.; Lei, Y. A.

2017-05-01

Recently, the stationary high confinement operations with improved pedestal conditions have been achieved in DIII-D [K. H. Burrell et al., Phys. Plasmas 23, 056103 (2016)], accompanying the spontaneous transition from the coherent edge harmonic oscillation (EHO) to the broadband MHD turbulence state by reducing the neutral beam injection torque to zero. It is highly significant for the burning plasma devices such as ITER. Simulations about the effects of E × B shear flow on the quiescent H-mode (QH-mode) are carried out using the three-field two-fluid model in the field-aligned coordinate under the BOUT++ framework. Using the shifted circular cross-section equilibriums including bootstrap current, the results demonstrate that the E × B shear flow strongly destabilizes low-n peeling modes, which are mainly driven by the gradient of parallel current in peeling-dominant cases and are sensitive to the Er shear. Adopting the much more general shape of E × B shear ( ω E = E r / R B θ ) profiles, the linear and nonlinear BOUT++ simulations show qualitative consistence with the experiments. The stronger shear flow shifts the most unstable mode to lower-n and narrows the mode spectrum. At the meantime, the nonlinear simulations of the QH-mode indicate that the shear flow in both co- and counter directions of diamagnetic flow has some similar effects. The nonlinear mode interaction is enhanced during the mode amplitude saturation phase. These results reveal that the fundamental physics mechanism of the QH-mode may be shear flow and are significant for understanding the mechanism of EHO and QH-mode.

Impact of E × B shear flow on low-n MHD instabilities

PubMed Central

Chen, J. G.; Ma, C. H.; Xi, P. W.; Lei, Y. A.

2017-01-01

Recently, the stationary high confinement operations with improved pedestal conditions have been achieved in DIII-D [K. H. Burrell et al., Phys. Plasmas 23, 056103 (2016)], accompanying the spontaneous transition from the coherent edge harmonic oscillation (EHO) to the broadband MHD turbulence state by reducing the neutral beam injection torque to zero. It is highly significant for the burning plasma devices such as ITER. Simulations about the effects of E × B shear flow on the quiescent H-mode (QH-mode) are carried out using the three-field two-fluid model in the field-aligned coordinate under the BOUT++ framework. Using the shifted circular cross-section equilibriums including bootstrap current, the results demonstrate that the E × B shear flow strongly destabilizes low-n peeling modes, which are mainly driven by the gradient of parallel current in peeling-dominant cases and are sensitive to the Er shear. Adopting the much more general shape of E × B shear (ωE=Er/RBθ) profiles, the linear and nonlinear BOUT++ simulations show qualitative consistence with the experiments. The stronger shear flow shifts the most unstable mode to lower-n and narrows the mode spectrum. At the meantime, the nonlinear simulations of the QH-mode indicate that the shear flow in both co- and counter directions of diamagnetic flow has some similar effects. The nonlinear mode interaction is enhanced during the mode amplitude saturation phase. These results reveal that the fundamental physics mechanism of the QH-mode may be shear flow and are significant for understanding the mechanism of EHO and QH-mode. PMID:28579732

The role of zonal flows and predator–prey oscillations in triggering the formation of edge and core transport barriers

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schmitz, Lothar; Zeng, Lei; Rhodes, Terry L.

2014-04-24

Here, we present direct evidence of low frequency, radially sheared, turbulence-driven flows (zonal flows (ZFs)) triggering edge transport barrier formation preceding the L- to H-mode transition via periodic turbulence suppression in limit-cycle oscillations (LCOs), consistent with predator–prey dynamics. The final transition to edge-localized mode-free H-mode occurs after the equilibrium E × B flow shear increases due to ion pressure profile evolution. ZFs are also observed to initiate formation of an electron internal transport barrier (ITB) at the q = 2 rational surface via local suppression of electron-scale turbulence. Multi-channel Doppler backscattering (DBS) has revealed the radial structure of the ZF-induced shear layer and the E × B shearing rate, ω E×B, in both barrier types. During edge barrier formation, the shearing rate lags the turbulence envelope during the LCO by 90°, transitioning to anti-correlation (180°) when the equilibrium shear dominates the turbulence-driven flow shear due to the increasing edge pressure gradient. The time-dependent flow shear and the turbulence envelope are anti-correlated (180° out of phase) in the electron ITB. LCOs with time-reversed evolution dynamics (transitioning from an equilibrium-flow dominated to a ZF-dominated state) have also been observed during the H–L back-transition and are potentially of interest for controlled ramp-down of the plasma stored energy and pressure (normalized to the poloidal magnetic field)more » $$\\beta_{\\theta} =2\\mu_{0} n{( {T_{{\\rm e}} +T_{{\\rm i}}})}/{B_{\\theta}^{2}}$$ in ITER.« less

The role of zonal flows and predator-prey oscillations in triggering the formation of edge and core transport barriers

NASA Astrophysics Data System (ADS)

Schmitz, L.; Zeng, L.; Rhodes, T. L.; Hillesheim, J. C.; Peebles, W. A.; Groebner, R. J.; Burrell, K. H.; McKee, G. R.; Yan, Z.; Tynan, G. R.; Diamond, P. H.; Boedo, J. A.; Doyle, E. J.; Grierson, B. A.; Chrystal, C.; Austin, M. E.; Solomon, W. M.; Wang, G.

2014-07-01

We present direct evidence of low frequency, radially sheared, turbulence-driven flows (zonal flows (ZFs)) triggering edge transport barrier formation preceding the L- to H-mode transition via periodic turbulence suppression in limit-cycle oscillations (LCOs), consistent with predator-prey dynamics. The final transition to edge-localized mode-free H-mode occurs after the equilibrium E × B flow shear increases due to ion pressure profile evolution. ZFs are also observed to initiate formation of an electron internal transport barrier (ITB) at the q = 2 rational surface via local suppression of electron-scale turbulence. Multi-channel Doppler backscattering (DBS) has revealed the radial structure of the ZF-induced shear layer and the E × B shearing rate, ωE×B, in both barrier types. During edge barrier formation, the shearing rate lags the turbulence envelope during the LCO by 90°, transitioning to anti-correlation (180°) when the equilibrium shear dominates the turbulence-driven flow shear due to the increasing edge pressure gradient. The time-dependent flow shear and the turbulence envelope are anti-correlated (180° out of phase) in the electron ITB. LCOs with time-reversed evolution dynamics (transitioning from an equilibrium-flow dominated to a ZF-dominated state) have also been observed during the H-L back-transition and are potentially of interest for controlled ramp-down of the plasma stored energy and pressure (normalized to the poloidal magnetic field) \\beta_{\\theta} =2\\mu_{0} n{( {T_{e} +T_{i}})}/{B_{\\theta}^{2}} in ITER.

The mean and turbulent flow structure of a weak hydraulic jump

NASA Astrophysics Data System (ADS)

Misra, S. K.; Kirby, J. T.; Brocchini, M.; Veron, F.; Thomas, M.; Kambhamettu, C.

2008-03-01

The turbulent air-water interface and flow structure of a weak, turbulent hydraulic jump are analyzed in detail using particle image velocimetry measurements. The study is motivated by the need to understand the detailed dynamics of turbulence generated in steady spilling breakers and the relative importance of the reverse-flow and breaker shear layer regions with attention to their topology, mean flow, and turbulence structure. The intermittency factor derived from turbulent fluctuations of the air-water interface in the breaker region is found to fit theoretical distributions of turbulent interfaces well. A conditional averaging technique is used to calculate ensemble-averaged properties of the flow. The computed mean velocity field accurately satisfies mass conservation. A thin, curved shear layer oriented parallel to the surface is responsible for most of the turbulence production with the turbulence intensity decaying rapidly away from the toe of the breaker (location of largest surface curvature) with both increasing depth and downstream distance. The reverse-flow region, localized about the ensemble-averaged free surface, is characterized by a weak downslope mean flow and entrainment of water from below. The Reynolds shear stress is negative in the breaker shear layer, which shows that momentum diffuses upward into the shear layer from the flow underneath, and it is positive just below the mean surface indicating a downward flux of momentum from the reverse-flow region into the shear layer. The turbulence structure of the breaker shear layer resembles that of a mixing layer originating from the toe of the breaker, and the streamwise variations of the length scale and growth rate are found to be in good agreement with observed values in typical mixing layers. All evidence suggests that breaking is driven by a surface-parallel adverse pressure gradient and a streamwise flow deceleration at the toe of the breaker. Both effects force the shear layer to thicken rapidly, thereby inducing a sharp free surface curvature change at the toe.

Cross-axis synchronous flow-through coil planet centrifuge for large-scale preparative counter-current chromatography. III. Performance of large-bore coils in slow planetary motion.

PubMed

Ito, Y; Zhang, T Y

1988-11-25

A preparative capability of the present cross-axis synchronous flow-through coil planet centrifuge was demonstrated with 0.5 cm I.D. multilayer coils. Results of the model studies with short coils indicated that the optimal separations are obtained at low revolutional speeds of 100-200 rpm in both central and lateral coil positions. Preparative separations were successfully performed on 2.5-10 g quantities of test samples in a pair of multilayer coils connected in series with a total capacity of 2.5 l. The sample loading capacity will be scaled up in several folds by increasing the column width.

Direct numerical simulation of annular flows

NASA Astrophysics Data System (ADS)

Batchvarov, Assen; Kahouadji, Lyes; Chergui, Jalel; Juric, Damir; Shin, Seungwon; Craster, Richard V.; Matar, Omar K.

2017-11-01

Vertical counter-current two-phase flows are investigated using direct numerical simulations. The computations are carried out using Blue, a front-tracking-based CFD solver. Preliminary results show good qualitative agreement with experimental observations in terms of interfacial phenomena; these include three-dimensional, large-amplitude wave formation, the development of long ligaments, and droplet entrainment. The flooding phenomena in these counter current systems are closely investigated. The onset of flooding in our simulations is compared to existing empirical correlations such as Kutateladze-type and Wallis-type. The effect of varying tube diameter and fluid properties on the flooding phenomena is also investigated in this work. EPSRC, UK, MEMPHIS program Grant (EP/K003976/1), RAEng Research Chair (OKM).

Modeling of Turbulent Free Shear Flows

NASA Technical Reports Server (NTRS)

Yoder, Dennis A.; DeBonis, James R.; Georgiadis, Nicolas J.

2013-01-01

The modeling of turbulent free shear flows is crucial to the simulation of many aerospace applications, yet often receives less attention than the modeling of wall boundary layers. Thus, while turbulence model development in general has proceeded very slowly in the past twenty years, progress for free shear flows has been even more so. This paper highlights some of the fundamental issues in modeling free shear flows for propulsion applications, presents a review of past modeling efforts, and identifies areas where further research is needed. Among the topics discussed are differences between planar and axisymmetric flows, development versus self-similar regions, the effect of compressibility and the evolution of compressibility corrections, the effect of temperature on jets, and the significance of turbulent Prandtl and Schmidt numbers for reacting shear flows. Large eddy simulation greatly reduces the amount of empiricism in the physical modeling, but is sensitive to a number of numerical issues. This paper includes an overview of the importance of numerical scheme, mesh resolution, boundary treatment, sub-grid modeling, and filtering in conducting a successful simulation.

Geometric flow control of shear bands by suppression of viscous sliding

PubMed Central

Viswanathan, Koushik; Mahato, Anirban; Sundaram, Narayan K.; M'Saoubi, Rachid; Trumble, Kevin P.; Chandrasekar, Srinivasan

2016-01-01

Shear banding is a plastic flow instability with highly undesirable consequences for metals processing. While band characteristics have been well studied, general methods to control shear bands are presently lacking. Here, we use high-speed imaging and micro-marker analysis of flow in cutting to reveal the common fundamental mechanism underlying shear banding in metals. The flow unfolds in two distinct phases: an initiation phase followed by a viscous sliding phase in which most of the straining occurs. We show that the second sliding phase is well described by a simple model of two identical fluids being sheared across their interface. The equivalent shear band viscosity computed by fitting the model to experimental displacement profiles is very close in value to typical liquid metal viscosities. The observation of similar displacement profiles across different metals shows that specific microstructure details do not affect the second phase. This also suggests that the principal role of the initiation phase is to generate a weak interface that is susceptible to localized deformation. Importantly, by constraining the sliding phase, we demonstrate a material-agnostic method—passive geometric flow control—that effects complete band suppression in systems which otherwise fail via shear banding. PMID:27616920

Effect of shear stress on platelet adhesion to expanded polytetrafluoroethylene, a silicone sheet, and an endothelial cell monolayer.

PubMed

Furukawa, K S; Ushida, T; Sugano, H; Tamaki, T; Ohshima, N; Tateishi, T

2000-01-01

We visualized in real-time platelets adhering to the surface of three representative biomaterials, by using an apparatus consisting of a modified cone and plate rheometer combined with an upright epifluorescence microscope under two shear flows (0.1 and 5.0 dyne/cm2). The materials were expanded polytetrafluoroethylene (ePTFE), silicone sheet, and a monolayer of bovine endothelial cells (ECs) formed on glass, all of which are opaque materials used for artificial blood vessels and medical devices. According to quantitative analysis, the monolayer of ECs formed on glass had better blood compatibility than did either the ePTFE or the silicone sheet under shear flow conditions. Under a shear flow condition of 0.1 dyne/cm2, platelet adhesion was silicone sheet > ePTFE. In contrast, under a shear flow condition of 5.0 dyne/cm2, ePTFE > silicone sheet. These results indicate that the intensity of shear stress could modify the order of hemocompatibility of the materials. Therefore, direct observation of platelet adhesion under shear flow conditions is indispensable for testing and screening biomaterials and for providing a precise quantitative evaluation of platelet adhesion.

Geometric flow control of shear bands by suppression of viscous sliding

NASA Astrophysics Data System (ADS)

Sagapuram, Dinakar; Viswanathan, Koushik; Mahato, Anirban; Sundaram, Narayan K.; M'Saoubi, Rachid; Trumble, Kevin P.; Chandrasekar, Srinivasan

2016-08-01

Shear banding is a plastic flow instability with highly undesirable consequences for metals processing. While band characteristics have been well studied, general methods to control shear bands are presently lacking. Here, we use high-speed imaging and micro-marker analysis of flow in cutting to reveal the common fundamental mechanism underlying shear banding in metals. The flow unfolds in two distinct phases: an initiation phase followed by a viscous sliding phase in which most of the straining occurs. We show that the second sliding phase is well described by a simple model of two identical fluids being sheared across their interface. The equivalent shear band viscosity computed by fitting the model to experimental displacement profiles is very close in value to typical liquid metal viscosities. The observation of similar displacement profiles across different metals shows that specific microstructure details do not affect the second phase. This also suggests that the principal role of the initiation phase is to generate a weak interface that is susceptible to localized deformation. Importantly, by constraining the sliding phase, we demonstrate a material-agnostic method-passive geometric flow control-that effects complete band suppression in systems which otherwise fail via shear banding.

CT scanning and flow measurements of shale fractures after multiple shearing events

DOE PAGES

Crandall, Dustin; Moore, Johnathan; Gill, Magdalena; ...

2017-11-05

A shearing apparatus was used in conjunction with a Hassler-style core holder to incrementally shear fractured shale cores while maintaining various confining pressures. Computed tomography scans were performed after each shearing event, and were used to obtain information on evolving fracture geometry. Fracture transmissivity was measured after each shearing event to understand the hydrodynamic response to the evolving fracture structure. The digital fracture volumes were used to perform laminar single phase flow simulations (local cubic law with a tapered plate correction model) to qualitatively examine small scale flow path variations within the altered fractures. Fractures were found to generally increasemore » in aperture after several shear slip events, with corresponding transmissivity increases. Lower confining pressure resulted in a fracture more prone to episodic mechanical failure and sudden changes in transmissivity. Conversely, higher confining pressures resulted in a system where, after an initial setting of the fracture surfaces, changes to the fracture geometry and transmissivity occurred gradually. Flow paths within the fractures are largely controlled by the location and evolution of zero aperture locations. Lastly, a reduction in the number of primary flow pathways through the fracture, and an increase in their width, was observed during all shearing tests.« less

Steady shear flow properties of Cordia myxa leaf gum as a function of concentration and temperature.

PubMed

Chaharlang, Mahmood; Samavati, Vahid

2015-08-01

The steady shear flow properties of dispersions of Cordia myxa leaf gum (CMLG) were determined as a function of concentration (0.5-2.5%, w/w), and temperature (10-50 °C). The CMLG dispersions exhibited strong shear-thinning behavior at all concentrations and temperatures. The Power-law (Ostwald-Waele's) and Herschel-Bulkley models were employed to characterize flow behavior of CMLG solutions at 0.1-100 s(-1) shear rate. Non-Newtonian shear-thinning behavior was observed at all temperatures and concentrations. While increase in temperature decreased the viscosity and increased the flow behavior indices, adverse effect was obtained by increasing the concentration. The Power-law model was found the best model to describe steady shear flow behavior of CMLG. The pseudoplasticity of CMLG increased markedly with concentration. An Arrhenius-type model was also used to describe the effect of temperature. The activation energy (Ea) appeared in the range of 5.972-18.104 kJ/mol, as concentration increased from 0.5% to 2.5%, at a shear rate of 10 s(-1). Copyright © 2015 Elsevier B.V. All rights reserved.

CT scanning and flow measurements of shale fractures after multiple shearing events

DOE Office of Scientific and Technical Information (OSTI.GOV)

Crandall, Dustin; Moore, Johnathan; Gill, Magdalena

A shearing apparatus was used in conjunction with a Hassler-style core holder to incrementally shear fractured shale cores while maintaining various confining pressures. Computed tomography scans were performed after each shearing event, and were used to obtain information on evolving fracture geometry. Fracture transmissivity was measured after each shearing event to understand the hydrodynamic response to the evolving fracture structure. The digital fracture volumes were used to perform laminar single phase flow simulations (local cubic law with a tapered plate correction model) to qualitatively examine small scale flow path variations within the altered fractures. Fractures were found to generally increasemore » in aperture after several shear slip events, with corresponding transmissivity increases. Lower confining pressure resulted in a fracture more prone to episodic mechanical failure and sudden changes in transmissivity. Conversely, higher confining pressures resulted in a system where, after an initial setting of the fracture surfaces, changes to the fracture geometry and transmissivity occurred gradually. Flow paths within the fractures are largely controlled by the location and evolution of zero aperture locations. Lastly, a reduction in the number of primary flow pathways through the fracture, and an increase in their width, was observed during all shearing tests.« less

Numerical modelling of strain in lava tubes

NASA Astrophysics Data System (ADS)

Merle, Olivier

The strain within lava tubes is described in terms of pipe flow. Strain is partitioned into three components: (a) two simple shear components acting from top to bottom and from side to side of a rectangular tube in transverse section; and (b) a pure shear component corresponding to vertical shortening in a deflating flow and horizontal compression in an inflating flow. The sense of shear of the two simple shear components is reversed on either side of a central zone of no shear. Results of numerical simulations of strain within lava tubes reveal a concentric pattern of flattening planes in section normal to the flow direction. The central node is a zone of low strain, which increases toward the lateral borders. Sections parallel to the flow show obliquity of the flattening plane to the flow axis, constituting an imbrication. The strain ellipsoid is generally of plane strain type, but can be of constriction or flattening type if thinning (i.e. deflating flow) or thickening (i.e. inflating flow) is superimposed on the simple shear regime. The strain pattern obtained from numerical simulation is then compared with several patterns recently described in natural lava flows. It is shown that the strain pattern revealed by AMS studies or crystal preferred orientations is remarkably similar to the numerical simulation. However, some departure from the model is found in AMS measurements. This may indicate inherited strain recorded during early stages of the flow or some limitation of the AMS technique.

Shear thinning and shear thickening of a confined suspension of vesicles

NASA Astrophysics Data System (ADS)

Nait Ouhra, A.; Farutin, A.; Aouane, O.; Ez-Zahraouy, H.; Benyoussef, A.; Misbah, C.

2018-01-01

Widely regarded as an interesting model system for studying flow properties of blood, vesicles are closed membranes of phospholipids that mimic the cytoplasmic membranes of red blood cells. In this study we analyze the rheology of a suspension of vesicles in a confined geometry: the suspension, bound by two planar rigid walls on each side, is subject to a shear flow. Flow properties are then analyzed as a function of shear rate γ ˙, the concentration of the suspension ϕ , and the viscosity contrast λ =ηin/ηout , where ηin and ηout are the fluid viscosities of the inner and outer fluids, respectively. We find that the apparent (or effective viscosity) of the suspension exhibits both shear thinning (decreasing viscosity with shear rate) or shear thickening (increasing viscosity with shear rate) in the same concentration range. The shear thinning or thickening behaviors appear as subtle phenomena, dependant on viscosity contrast λ . We provide physical arguments on the origins of these behaviors.

Characterizing a middle to upper crustal shear zone: Microstructures, quartz c-axis fabrics, deformation temperatures and flow vorticity analysis of the northern Ailao Shan-Red River shear zone, China

NASA Astrophysics Data System (ADS)

Wu, Wenbin; Liu, Junlai; Zhang, Lisheng; Qi, Yinchuan; Ling, Chengyang

2017-05-01

Structural and microstructural characteristics, deformation temperatures and flow vorticities of the northern Ailao Shan (ALS) high-grade metamorphic belt provide significant information regarding the nature and tectonic evolution of the Ailao Shan-Red River (ASRR) shear zone. Mineral deformation mechanisms, quartz lattice-preferred orientation (LPO) patterns and the opening angles of quartz c-axis fabrics of samples from the Gasa section indicate that the northern ALS high-grade metamorphic belt has experienced progressive shear deformation. The early stage shearing is characterized by a gradual decrease of deformation temperatures from >650 °C at the northeastern unit to ca. 300 °C at the southwestern unit, that results in the formation of migmatites, mylonitic gneisses, thin bedded mylonites, mylonitic schists and phyllonites from the NE to SW across the strike of the shear zone. The late stage low-temperature (300-400 °C) shearing is superimposed on the early deformation throughout the belt with the formation of discrete, small-scale shear zones, especially in the thin-banded mylonitic rocks along both margins. The kinematic vorticity values estimated by rotated rigid porphyroclast method and oblique grain-shaped/quartz c-axis-fabric method imply that the general shear-dominated flow (0.49-0.77) progressively changed to a simple shear-dominated flow (0.77-1) toward the late stage of ductile deformation. The two stages of shearing are consistent with early shortening-dominated and late extrusion-controlled regional tectonic processes. The transition between them occurred at ca. 27 Ma in the ALS high-grade metamorphic belt along the ASRR shear zone. The large amount of strike-slip displacement along the ASRR shear zone is predominantly attributed to accelerated flow along the shear zone during the late extrusion-controlled tectonic process.

Spiral counter-current chromatography of small molecules, peptides and proteins using the spiral tubing support rotor.

PubMed

Knight, Martha; Finn, Thomas M; Zehmer, John; Clayton, Adam; Pilon, Aprile

2011-09-09

An important advance in countercurrent chromatography (CCC) carried out in open flow-tubing coils, rotated in planetary centrifuges, is the new design to spread out the tubing in spirals. More spacing between the tubing was found to significantly increase the stationary phase retention, such that now all types of two-phase solvent systems can be used for liquid-liquid partition chromatography in the J-type planetary centrifuges. A spiral tubing support (STS) frame with circular channels was constructed by laser sintering technology into which FEP tubing was placed in 4 spiral loops per layer from the bottom to the top and a cover affixed allowing the tubing to connect to flow-tubing of the planetary centrifuge. The rotor was mounted and run in a P.C. Inc. type instrument. Examples of compounds of molecular weights ranging from <300 to approximately 15,000 were chromatographed in appropriate two-phase solvent systems to assess the capability for separation and purification. A mixture of small molecules including aspirin was completely separated in hexane-ethyl acetate-methanol-water. Synthetic peptides including a very hydrophobic peptide were each purified to a very high purity level in a sec-butanol solvent system. In the STS rotor high stationary phase retention was possible with the aqueous sec-butanol solvent system at a normal flow rate. Finally, the two-phase aqueous polyethylene glycol-potassium phosphate solvent system was applied to separate a protein from a lysate of an Escherichia coli expression system. These experiments demonstrate the versatility of spiral CCC using the STS rotor. Copyright © 2011 Elsevier B.V. All rights reserved.

Modeling pH-zone refining countercurrent chromatography: a dynamic approach.

PubMed

Kotland, Alexis; Chollet, Sébastien; Autret, Jean-Marie; Diard, Catherine; Marchal, Luc; Renault, Jean-Hugues

2015-04-24

A model based on mass transfer resistances and acid-base equilibriums at the liquid-liquid interface was developed for the pH-zone refining mode when it is used in countercurrent chromatography (CCC). The binary separation of catharanthine and vindoline, two alkaloids used as starting material for the semi-synthesis of chemotherapy drugs, was chosen for the model validation. Toluene/CH3CN/water (4/1/5, v/v/v) was selected as biphasic solvent system. First, hydrodynamics and mass transfer were studied by using chemical tracers. Trypan blue only present in the aqueous phase allowed the determination of the parameters τextra and Pe for hydrodynamic characterization whereas acetone, which partitioned between the two phases, allowed the determination of the transfer parameter k0a. It was shown that mass transfer was improved by increasing both flow rate and rotational speed, which is consistent with the observed mobile phase dispersion. Then, the different transfer parameters of the model (i.e. the local transfer coefficient for the different species involved in the process) were determined by fitting experimental concentration profiles. The model accurately predicted both equilibrium and dynamics factors (i.e. local mass transfer coefficients and acid-base equilibrium constant) variation with the CCC operating conditions (cell number, flow rate, rotational speed and thus stationary phase retention). The initial hypotheses (the acid-base reactions occurs instantaneously at the interface and the process is mainly governed by mass transfer) are thus validated. Finally, the model was used as a tool for catharanthine and vindoline separation prediction in the whole experimental domain that corresponded to a flow rate between 20 and 60 mL/min and rotational speeds from 900 and 2100 rotation per minutes. Copyright © 2015 Elsevier B.V. All rights reserved.

F-actin and microtubule suspensions as indeterminate fluids.

PubMed

Buxbaum, R E; Dennerll, T; Weiss, S; Heidemann, S R

1987-03-20

The viscosity of F-actin and microtubule suspensions has been measured as a function of shear rate with a Weissenberg rheogoniometer. At shear rates of less than 1.0 per second the viscosity of suspensions of these two structural proteins is inversely proportional to shear rate. These results are consistent with previous in vivo measurements of the viscosity of cytoplasm. This power law implies that shear stress is independent of shear rate; that is, shear stress is a constant at all shear rates less than 1.0 per second. Thus the flow profile of these fluids is indeterminate, or nearly so. This flow property may explain several aspects of intracellular motility in living cells. Possible explanations for this flow property are based on a recent model for semidilute suspensions of rigid rods or a classical friction model for liquid crystals.

Contribution of peculiar shear motions to large-scale structure

NASA Technical Reports Server (NTRS)

Mueler, Hans-Reinhard; Treumann, Rudolf A.

1994-01-01

Self-gravitating shear flow instability simulations in a cold dark matter-dominated expanding Einstein-de Sitter universe have been performed. When the shear flow speed exceeds a certain threshold, self-gravitating Kelvin-Helmoholtz instability occurs, forming density voids and excesses along the shear flow layer which serve as seeds for large-scale structure formation. A possible mechanism for generating shear peculiar motions are velocity fluctuations induced by the density perturbations of the postinflation era. In this scenario, short scales grow earlier than large scales. A model of this kind may contribute to the cellular structure of the luminous mass distribution in the universe.

Effects of shear flow on phase nucleation and crystallization.

PubMed

Mura, Federica; Zaccone, Alessio

2016-04-01

Classical nucleation theory offers a good framework for understanding the common features of new phase formation processes in metastable homogeneous media at rest. However, nucleation processes in liquids are ubiquitously affected by hydrodynamic flow, and there is no satisfactory understanding of whether shear promotes or slows down the nucleation process. We developed a classical nucleation theory for sheared systems starting from the molecular level of the Becker-Doering master kinetic equation and we analytically derived a closed-form expression for the nucleation rate. The theory accounts for the effect of flow-mediated transport of molecules to the nucleus of the new phase, as well as for the mechanical deformation imparted to the nucleus by the flow field. The competition between flow-induced molecular transport, which accelerates nucleation, and flow-induced nucleus straining, which lowers the nucleation rate by increasing the nucleation energy barrier, gives rise to a marked nonmonotonic dependence of the nucleation rate on the shear rate. The theory predicts an optimal shear rate at which the nucleation rate is one order of magnitude larger than in the absence of flow.

The effects of forcing on a single stream shear layer and its parent boundary layer

NASA Technical Reports Server (NTRS)

Haw, Richard C.; Foss, John F.

1990-01-01

Forcing and its effect on fluid flows has become an accepted tool in the study and control of flow systems. It has been used both as a diagnostic tool, to explore the development and interaction of coherent structures, and as a method of controlling the behavior of the flow. A number of forcing methods have been used in order to provide a perturbation to the flow; among these are the use of an oscillating trailing edge, acoustically driven slots, external acoustic forcing, and mechanical piston methods. The effect of a planar mechanical piston forcing on a single stream shear layer is presented; it can be noted that this is one of the lesser studied free shear layers. The single stream shear layer can be characterized by its primary flow velocity scale and the thickness of the separating boundary layer. The velocity scale is constant over the length of the flow field; theta (x) can be used as a width scale to characterize the unforced shear layer. In the case of the forced shear layer the velocity field is a function of phase time and definition of a width measure becomes somewhat problematic.

pH-zone-refining elution-extrusion countercurrent chromatography: Separation of hydroxyanthraquinones from Cassiae semen.

PubMed

Bu, Zhisi; Lv, Liqiong; Li, Xingnuo; Chu, Chu; Tong, Shengqiang

2017-11-01

Seven hydroxyanthraquinones were successfully separated from the traditional Chinese medicinal herb Cassiae semen by conventional and pH-zone-refining countercurrent chromatography with an environmentally friendly biphasic solvent system, in which elution-extrusion mode was investigated for pH-zone-refining countercurrent chromatography for the first time. A two-phase solvent system composed of n-hexane/ethyl acetate/ethanol/water (5:3:4:4, v/v/v/v) was used for the conventional countercurrent chromatography while the same system with a different volume ratio n-hexane/ethyl acetate/ethanol/water (3:5:2:6, v/v/v/v) was used for pH-zone-refining countercurrent chromatography, in which 20 mmol/L of trifluoroacetic acid was added in the organic phase as a retainer and 15 mmol/L of ammonia was added to the aqueous phase as an eluter. A 400 mg crude sample could be well separated by pH-zone-refining countercurrent chromatography, yielding 53 mg of aurantio-obtusin, 40 mg of chryso-obtusin, 18 mg of obtusin, 24 mg of obtusifolin, 10 mg of emodin, and 105 mg of the mixture of chrysophanol and physcion with a purity of over 95.8, 95.7, 96.9, 93.5, 97.4, 77.1, and 19.8%, as determined by high-performance liquid chromatography. Furthermore, the difference in elution sequence between conventional and pH-zone-refining mode was observed and discussed. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Single molecule studies of flexible polymers under shear and mixed flows

NASA Astrophysics Data System (ADS)

Teixeira, Rodrigo Esquivel

We combine manipulation and single molecule visualization of flexible DNA polymers with the generation of controlled simple shear and planar mixed flows for the investigation of polymer flow physics. With the ability to observe polymer conformation directly and follow its evolution in both dilute and entangled regimes we provide a direct test for molecular models. The coil-stretch transition of polymer extension was investigated in planar mixed flows approaching simple shear. Visualization of individual molecules revealed a sharp coil-stretch transition in the steady-state length of the polymer with increasing strain rate in flows slightly more straining than rotational. In slightly more rotational flows significant transient polymer deformation was observed. Next, dilute polymers were visualized in the flow-gradient plane of a steady shear flow. By exploiting the linear proportionality between polymer mass and image intensity, the radius of gyration tensor elements ( Gij) were measured over time. Then, the Giesekus stress tensor was used to obtain the bulk shear viscosity and first normal stress coefficient, thus performing rheology measurements from single molecule conformations. End-over-end tumbling was discovered for the first time, confirming a long-standing prediction and numerous single-chain computer simulation studies. The tumbling frequency followed Wi0.62, and an equation derived from simple advection and diffusion arguments was able to reproduce these observations. Power spectral densities of chain orientation trajectories were found to be single-peaked around the tumbling frequency, thus suggesting a periodic character for polymer dynamics. Finally, we investigated well-entangled polymer solutions. Identical preparations were used in both rheological characterizations and single molecule observations under a variety of shear flow histories. Polymer extension relaxations after the cessation of a fast shear flow revealed two intrinsic characteristic times. The fast one was insensitive to concentration and at least an order of magnitude larger than the Rouse time presupposed by theoretical treatments. The slow timescale grew steeply with concentration, in qualitative agreement with theory. Transient and steady shear flows showed vastly different conformations even among identical molecules subjected to identical flow histories. This "molecular individualism" of well-entangled solutions and its broad conformational distributions calls into question the validity of preaveraging approximations made in molecular-level theories.

Turbulence in Internal Flows. Turbomachinery and Other Applications

DTIC Science & Technology

1977-05-01

are things we shall look for in our sheared cellular flow. One of the things that is fairly typical for nearly homogeneous turbulent shear flow, and... One of the things that we hoped to learn from our sheared cellular flow computations was information about this particular attribute. Slide No. 5...typical temperature difference was on the order of a couple of degrees Centigrade, the lower side being the hotter. We did in fact do some checks: things

Novel Imaging Method of Continuous Shear Wave by Ultrasonic Color Flow Mapping

NASA Astrophysics Data System (ADS)

Yamakoshi, Yoshiki; Yamamoto, Atsushi; Yuminaka, Yasushi

Shear wave velocity measurement is a promising method in evaluation of tissue stiffness. Several methods have been developed to measure the shear wave velocity, however, it is difficult to obtain quantitative shear wave image in real-time by low cost system. In this paper, a novel shear wave imaging method for continuous shear wave is proposed. This method uses a color flow imaging which is used in ultrasonic imaging system to obtain shear wave's wavefront map. Two conditions, shear wave frequency condition and shear wave displacement amplitude condition, are required, however, these conditions are not severe restrictions in most applications. Using the proposed method, shear wave velocity of trapezius muscle is measured. The result is consistent with the velocity which is calculated from shear elastic modulus measured by ARFI method.

Rapid expulsion of microswimmers by a vortical flow

DOE PAGES

Sokolov, Andrey; Aranson, Igor S.

2016-03-23

Interactions of microswimmers with their fluid environment are exceptionally complex. Macroscopic shear flow alters swimming trajectories in a highly nontrivial way and results in dramatic reduction of viscosity and heterogeneous bacterial distributions. Here we report on experimental and theoretical studies of rapid expulsion of microswimmers, such as motile bacteria, by a vortical flow created by a rotating microparticle. We observe a formation of a macroscopic depletion area in a high-shear region, in the vicinity of a microparticle. The rapid migration of bacteria from the shear-rich area is caused by a vortical structure of the flow rather than intrinsic random fluctuationsmore » of bacteria orientations, in stark contrast to planar shear flow. Our mathematical model reveals that expulsion is a combined effect of motility and alignment by a vortical flow. Our findings offer a novel approach for manipulation of motile microorganisms and shed light on bacteria-flow interactions.« less

Impact of finite rate chemistry on the hydrodynamic stability of shear flows in turbulent lean premixed combustion

NASA Astrophysics Data System (ADS)

Dagan, Yuval; Ghoniem, Ahmed

2017-11-01

Recent experimental observations show that the dynamic response of a reactive flow is strongly impacted by the fuel chemistry. In order to gain insight into some of the underlying mechanisms we formulate a new linear stability model that incorporates the impact of finite rate chemistry on the hydrodynamic stability of shear flows. Contrary to previous studies which typically assume that the velocity field is independent of the kinetic rates, the velocity field in our study is coupled with the temperature field. Using this formulation, we reproduce previous results, e.g., most unstable global modes, obtained for non-reacting shear flow. Moreover, we show that these modes are significantly altered in frequency and gain by the presence of a reaction region within the shear layer. This qualitatively agrees with results of our recent experimental and numerical studies, which show that the flame surface location relative to the shear layer influences the stability characteristics in combustion tunnels. This study suggests a physical explanation for the observed impact of finite rate chemistry on shear flow stability.

The effect of shear flow on the rotational diffusivity of a single axisymmetric particle

NASA Astrophysics Data System (ADS)

Leahy, Brian; Koch, Donald; Cohen, Itai

2014-11-01

Colloidal suspensions of nonspherical particles abound in the world around us, from red blood cells in arteries to kaolinite discs in clay. Understanding the orientation dynamics of these particles is important for suspension rheology and particle self-assembly. However, even for the simplest case of dilute suspensions in simple shear flow, the orientation dynamics of Brownian nonspherical particles are poorly understood at large shear rates. Here, we analytically calculate the time-dependent orientation distributions of particles confined to the flow-gradient plane when the rotary diffusion is small but nonzero. For both startup and oscillatory shear flows, we find a coordinate change that maps the convection-diffusion equation to a simple diffusion equation with an enhanced diffusion constant, simplifying the orientation dynamics. For oscillatory shear, this enhanced diffusion drastically alters the quasi-steady orientation distributions. Our theory of the unsteady orientation dynamics provides an understanding of a nonspherical particle suspension's rheology for a large class of unsteady flows. For particles with aspect ratio 10 under oscillatory shear, the rotary diffusion and intrinsic viscosity vary with amplitude by a factor of ~ 40 and ~ 2 , respectively.

Correlation between vortices and wall shear stress in a curved artery model under pulsatile flow conditions

NASA Astrophysics Data System (ADS)

Cox, Christopher; Plesniak, Michael W.

2017-11-01

One of the most physiologically relevant factors within the cardiovascular system is the wall shear stress. The wall shear stress affects endothelial cells via mechanotransduction and atherosclerotic regions are strongly correlated with curvature and branching in the human vasculature, where the shear stress is both oscillatory and multidirectional. Also, the combined effect of curvature and pulsatility in cardiovascular flows produces unsteady vortices. In this work, our goal is to assess the correlation between multiple vortex pairs and wall shear stress. To accomplish this, we use an in-house high-order flux reconstruction Navier-Stokes solver to simulate pulsatile flow of a Newtonian blood-analog fluid through a rigid 180° curved artery model. We use a physiologically relevant flow rate and generate results using both fully developed and uniform entrance conditions, the latter motivated by the fact that flow upstream to a curved artery may not be fully developed. Under these two inflow conditions, we characterize the evolution of various vortex pairs and their subsequent effect on several wall shear stress metrics. Supported by GW Center for Biomimetics and Bioinspired Engineering.

Shear flow and carbon nanotubes synergistically induced nonisothermal crystallization of poly(lactic acid) and its application in injection molding.

PubMed

Tang, Hu; Chen, Jing-Bin; Wang, Yan; Xu, Jia-Zhuang; Hsiao, Benjamin S; Zhong, Gan-Ji; Li, Zhong-Ming

2012-11-12

The effect of shear flow and carbon nanotubes (CNTs), separately and together, on nonisothermal crystallization of poly(lactic acid) (PLA) at a relatively large cooling rate was investigated by time-resolved synchrotron wide-angle X-ray diffraction (WAXD) and polarized optical microscope (POM). Unlike flexible-chain polymers such as polyethylene, and so on, whose crystallization kinetics are significantly accelerated by shear flow, neat PLA only exhibits an increase in onset crystallization temperature after experiencing a shear rate of 30 s(-1), whereas both the nucleation density and ultimate crystallinity are not changed too much because PLA chains are intrinsically semirigid and have relatively short length. The breaking down of shear-induced nuclei into point-like precursors (or random coil) probably becomes increasingly active after shear stops. Very interestingly, a marked synergistic effect of shear flow and CNTs exists in enhancing crystallization of PLA, leading to a remarkable increase of nucleation density in PLA/CNT nanocomposite. This synergistic effect is ascribed to extra nuclei, which are formed by the anchoring effect of CNTs' surfaces on the shear-induced nuclei and suppressing effect of CNTs on the relaxation of the shear-induced nuclei. Further, this interesting finding was deliberately applied to injection molding, aiming to improve the crystallinity of PLA products. As expected, a remarkable high crystallinity in the injection-molded PLA part has been achieved successfully by the combination of shear flow and CNTs, which offers a new method to fabricate PLA products with high crystallinity for specific applications.

Dynamics of intrinsic axial flows in unsheared, uniform magnetic fields

DOE Office of Scientific and Technical Information (OSTI.GOV)

Li, J. C.; Diamond, P. H.; Xu, X. Q.

2016-05-15

A simple model for the generation and amplification of intrinsic axial flow in a linear device, controlled shear decorrelation experiment, is proposed. This model proposes and builds upon a novel dynamical symmetry breaking mechanism, using a simple theory of drift wave turbulence in the presence of axial flow shear. This mechanism does not require complex magnetic field structure, such as shear, and thus is also applicable to intrinsic rotation generation in tokamaks at weak or zero magnetic shear, as well as to linear devices. This mechanism is essentially the self-amplification of the mean axial flow profile, i.e., a modulational instability.more » Hence, the flow development is a form of negative viscosity phenomenon. Unlike conventional mechanisms where the residual stress produces an intrinsic torque, in this dynamical symmetry breaking scheme, the residual stress induces a negative increment to the ambient turbulent viscosity. The axial flow shear is then amplified by this negative viscosity increment. The resulting mean axial flow profile is calculated and discussed by analogy with the problem of turbulent pipe flow. For tokamaks, the negative viscosity is not needed to generate intrinsic rotation. However, toroidal rotation profile gradient is enhanced by the negative increment in turbulent viscosity.« less

Simulation of Vortex Structure in Supersonic Free Shear Layer Using Pse Method

NASA Astrophysics Data System (ADS)

Guo, Xin; Wang, Qiang

The method of parabolized stability equations (PSE) are applied in the analysis of nonlinear stability and the simulation of flow structure in supersonic free shear layer. High accuracy numerical techniques including self-similar basic flow, high order differential method, appropriate transformation and decomposition of nonlinear terms are adopted and developed to solve the PSE effectively for free shear layer. The spatial evolving unstable waves which dominate the flow structure are investigated through nonlinear coupling spatial marching methods. The nonlinear interactions between harmonic waves are further analyzed and instantaneous flow field are obtained by adding the harmonic waves into basic flow. Relevant data agree well with that of DNS. The results demonstrate that T-S wave does not keeping growing exponential as the linear evolution, the energy transfer to high order harmonic modes and finally all harmonic modes get saturation due to the nonlinear interaction; Mean flow distortion is produced by the nonlinear interaction between the harmonic and its conjugate harmonic, makes great change to the average flow and increases the thickness of shear layer; PSE methods can well capture the large scale nonlinear flow structure in the supersonic free shear layer such as vortex roll-up, vortex pairing and nonlinear saturation.

Symmetry Breaking by Parallel Flow Shear

NASA Astrophysics Data System (ADS)

Li, Jiacong; Diamond, Patrick

2015-11-01

Plasma rotation is important in reducing turbulent transport, suppressing MHD instabilities, and is beneficial to confinement. Intrinsic rotation without an external momentum input is of interest for its plausible application on ITER. k∥ spectrum asymmetry is required for residual Reynolds stress that drives the intrinsic rotation. Parallel flows are reported in linear devices without magnetic shear. In CSDX, parallel flows are mostly peaked in the core [Thakur et al., 2014]; more robust flows and reversed profiles are seen in PANTA [Oldenburger, et al. 2012]. A novel mechanism for symmetry breaking in momentum transport is proposed. Magnetic shear or mean flow profile are not required. A seed parallel flow shear (PFS) sets the sign of residual stress by selecting certain modes to grow faster. The resulted spectrum imbalance leads to a nonzero residual stress, which further drives a parallel flow with ∇n as the free energy source, adding to the shear until saturated by diffusion. Balanced flow gradient is set by Π∥Res /χϕ . Residual stress is calculated for ITG turbulence and collisional drift wave turbulence where electron-ion and electron-neutral collisions are discussed and compared. Numerical simulation is proposed for testing the effect of PFS.

Phase behavior of a simple dipolar fluid under shear flow in an electric field.

PubMed

McWhirter, J Liam

2008-01-21

Nonequilibrium molecular dynamics simulations are performed on a dense simple dipolar fluid under a planar Couette shear flow. Shear generates heat, which is removed by thermostatting terms added to the equations of motion of the fluid particles. The spatial structure of simple fluids at high shear rates is known to depend strongly on the thermostatting mechanism chosen. Kinetic thermostats are either biased or unbiased: biased thermostats neglect the existence of secondary flows that appear at high shear rates superimposed upon the linear velocity profile of the fluid. Simulations that employ a biased thermostat produce a string phase where particles align in strings with hexagonal symmetry along the direction of the flow. This phase is known to be a simulation artifact of biased thermostatting, and has not been observed by experiments on colloidal suspensions under shear flow. In this paper, we investigate the possibility of using a suitably directed electric field, which is coupled to the dipole moments of the fluid particles, to stabilize the string phase. We explore several thermostatting mechanisms where either the kinetic or configurational fluid degrees of freedom are thermostated. Some of these mechanisms do not yield a string phase, but rather a shear-thickening phase; in this case, we find the influence of the dipolar interactions and external field on the packing structure, and in turn their influence on the shear viscosity at the onset of this shear-thickening regime.

Permeability evolution of shale during spontaneous imbibition

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chakraborty, N.; Karpyn, Z. T.; Liu, S.

Shales have small pore and throat sizes ranging from nano to micron scales, low porosity and limited permeability. The poor permeability and complex pore connectivity of shales pose technical challenges to (a) understanding flow and transport mechanisms in such systems and, (b) in predicting permeability changes under dynamic saturation conditions. This paper presents quantitative experimental evidence of the migration of water through a generic shale core plug using micro CT imaging. In addition, in-situ measurements of gas permeability were performed during counter-current spontaneous imbibition of water in nano-darcy permeability Marcellus and Haynesville core plugs. It was seen that water blocksmore » severely reduced the effective permeability of the core plugs, leading to losses of up to 99.5% of the initial permeability in experiments lasting 30 days. There was also evidence of clay swelling which further hindered gas flow. When results from this study were compared with similar counter-current gas permeability experiments reported in the literature, the initial (base) permeability of the rock was found to be a key factor in determining the time evolution of effective gas permeability during spontaneous imbibition. With time, a recovery of effective permeability was seen in the higher permeability rocks, while becoming progressively detrimental and irreversible in tighter rocks. Finally, these results suggest that matrix permeability of ultra-tight rocks is susceptible to water damage following hydraulic fracturing stimulation and, while shut-in/soaking time helps clearing-up fractures from resident fluid, its effect on the adjacent matrix permeability could be detrimental.« less

Permeability evolution of shale during spontaneous imbibition

DOE PAGES

Chakraborty, N.; Karpyn, Z. T.; Liu, S.; ...

2017-01-05

Shales have small pore and throat sizes ranging from nano to micron scales, low porosity and limited permeability. The poor permeability and complex pore connectivity of shales pose technical challenges to (a) understanding flow and transport mechanisms in such systems and, (b) in predicting permeability changes under dynamic saturation conditions. This paper presents quantitative experimental evidence of the migration of water through a generic shale core plug using micro CT imaging. In addition, in-situ measurements of gas permeability were performed during counter-current spontaneous imbibition of water in nano-darcy permeability Marcellus and Haynesville core plugs. It was seen that water blocksmore » severely reduced the effective permeability of the core plugs, leading to losses of up to 99.5% of the initial permeability in experiments lasting 30 days. There was also evidence of clay swelling which further hindered gas flow. When results from this study were compared with similar counter-current gas permeability experiments reported in the literature, the initial (base) permeability of the rock was found to be a key factor in determining the time evolution of effective gas permeability during spontaneous imbibition. With time, a recovery of effective permeability was seen in the higher permeability rocks, while becoming progressively detrimental and irreversible in tighter rocks. Finally, these results suggest that matrix permeability of ultra-tight rocks is susceptible to water damage following hydraulic fracturing stimulation and, while shut-in/soaking time helps clearing-up fractures from resident fluid, its effect on the adjacent matrix permeability could be detrimental.« less

Structural, micro-structural and kinematic analyses of channel flow in the Karmostaj salt diapir in the Zagros foreland folded belt, Fars province, Iran

NASA Astrophysics Data System (ADS)

Sarkarinejad, Khalil; Sarshar, Maryam Asadi; Adineh, Sadegh

2018-02-01

One of the main characteristic of the Zagros foreland fold-and-thrust belt and the Zagros foreland folded belt are wide distributions of surface extrusion from the Hormuz salt diapirs. This study examines the structure and kinematic of channel flow in the Karmostaj salt diapir in the southwestern part of the Zagros foreland folded belt. This diapir has reached the surface as a result of the channel flow mechanism and has extruded in the southern limb of the Kuh-Gach anticline which is an asymmetric décollement fold with convergence to the south. Structural and microstructural studies and quantitative finite strain (Rs) and kinematic vorticity number (Wk) analyses were carried out within this salt diapir and its namakier. This was in order to investigate the structural evolution in the salt diapiric system, the characteristics and mechanism of the salt flow and the distribution of flow regimes within the salt diapir and interaction of regional tectonics and salt diaprism. The extruded salt has developed a flow foliation sub-parallel to the remnant bedding recorded by different colors, a variety of internal folds including symmetrical and asymmetrical folds and interference fold patterns, shear zones, and boudins. These structures were used to analyze mechanisms and history of diapiric flow and extrusion. The microstructures, reveal various deformation mechanisms in various parts of salt diapir. The measurements of finite strain show that Rs values in the margin of salt diapir are higher than within its namakier which is consistent with the results of structural studies. Mean kinematic vorticity number (Wm) measured in steady state deformation of diapir and namakier is Wm = 0.45-0.48 ± 0.13. The estimated mean finite deformation (Wm) values indicate that 67.8% pure shear and 32.2% simple shear deformation were involved; the implications of which are discussed. The vorticity of flow indicates that in the early stage of growth, Poiseuille flow was the dominate mechanism, especially in the core of diapir with higher pure shear component relative to simple shear component, whilst a Couette flow at the margins of diapir is the dominate mechanism with higher simple shear component relative to pure shear component. The obtained kinematic vorticity number reflects spatial partitioning of dominantly Poiseuille flow in core and Couette flow along edges of diapir. These two mechanisms reflect a persistent flow governed by a simultaneous combination of pure shear and simple shear in a hybrid Poiseuille-Coutte Flow.

Multiple dual mode counter-current chromatography with variable duration of alternating phase elution steps.

PubMed

Kostanyan, Artak E; Erastov, Andrey A; Shishilov, Oleg N

2014-06-20

The multiple dual mode (MDM) counter-current chromatography separation processes consist of a succession of two isocratic counter-current steps and are characterized by the shuttle (forward and back) transport of the sample in chromatographic columns. In this paper, the improved MDM method based on variable duration of alternating phase elution steps has been developed and validated. The MDM separation processes with variable duration of phase elution steps are analyzed. Basing on the cell model, analytical solutions are developed for impulse and non-impulse sample loading at the beginning of the column. Using the analytical solutions, a calculation program is presented to facilitate the simulation of MDM with variable duration of phase elution steps, which can be used to select optimal process conditions for the separation of a given feed mixture. Two options of the MDM separation are analyzed: 1 - with one-step solute elution: the separation is conducted so, that the sample is transferred forward and back with upper and lower phases inside the column until the desired separation of the components is reached, and then each individual component elutes entirely within one step; 2 - with multi-step solute elution, when the fractions of individual components are collected in over several steps. It is demonstrated that proper selection of the duration of individual cycles (phase flow times) can greatly increase the separation efficiency of CCC columns. Experiments were carried out using model mixtures of compounds from the GUESSmix with solvent systems hexane/ethyl acetate/methanol/water. The experimental results are compared to the predictions of the theory. A good agreement between theory and experiment has been demonstrated. Copyright © 2014 Elsevier B.V. All rights reserved.

Direct measurements of local bed shear stress in the presence of pressure gradients

NASA Astrophysics Data System (ADS)

Pujara, Nimish; Liu, Philip L.-F.

2014-07-01

This paper describes the development of a shear plate sensor capable of directly measuring the local mean bed shear stress in small-scale and large-scale laboratory flumes. The sensor is capable of measuring bed shear stress in the range 200 Pa with an accuracy up to 1 %. Its size, 43 mm in the flow direction, is designed to be small enough to give spatially local measurements, and its bandwidth, 75 Hz, is high enough to resolve time-varying forcing. Typically, shear plate sensors are restricted to use in zero pressure gradient flows because secondary forces on the edge of the shear plate caused by pressure gradients can introduce large errors. However, by analysis of the pressure distribution at the edges of the shear plate in mild pressure gradients, we introduce a new methodology for correcting for the pressure gradient force. The developed sensor includes pressure tappings to measure the pressure gradient in the flow, and the methodology for correction is applied to obtain accurate measurements of bed shear stress under solitary waves in a small-scale wave flume. The sensor is also validated by measurements in a turbulent flat plate boundary layer in open channel flow.

Finite-beta and equilibrium sheared flow effects on core plasma turbulence and transport

NASA Astrophysics Data System (ADS)

Chen, Yang; Parker, Scott E.

2004-11-01

Recent GEM (Y. Chen and S. E. Parker, J. Comp. Phys. 189 (2003)463) simulations have revealed the following features of ITG turbulence and transport: (1) For η_e ˜η_i, as β increases the turbulence level and transport increase, leading to fast streamer transport for β ˜ β_crit/2, β_ crit the ideal ballooning limit; (2) Sheared E_r× B flow with shearing rate γ_E=(r/q)partial(qv_ E× B/r)/partial r ˜ γ readily stabilizes the linear eigenmode. However, starting with a nonlinear state obtained without sheared flow, and continue the simulation with a shearing rate γE ≤ 3γ, the turbulence and transport are reduced but not completely quenched, indicating that turbulence is nonlinearly self-sustained.(J. F. Drake, A. Zeiler and D. Biskamp, Phys. Rev. Lett 75 (1995) 4222) At β=0.4β_crit, turbulence is completely quenched only when the shearing rate far exceeds the linear growth rate; (3) As β increases, the shearing rate threshold at which the turbulence can self-sustain increases. Electromagnetic turbulence is more robust in the presence of sheared flow than electrostatic turbulence.

The interaction of two spheres in a simple-shear flow of complex fluids

NASA Astrophysics Data System (ADS)

Firouznia, Mohammadhossein; Metzger, Bloen; Ovarlez, Guillaume; Hormozi, Sarah

2017-11-01

We study the interaction of two small freely-moving spheres in a linear flow field of Newtonian, shear thinning and yield stress fluids. We perform a series of experiments over a range of shear rates as well as different shear histories using an original apparatus and with the aid of conventional rheometry, Particle Image Velocimetry and Particle Tracking Velocimetry. Showing that the non-Newtonian nature of the suspending fluid strongly affects the shape of particle trajectories and the irreversibility. An important point is that non-Newtonian effects can be varied and unusual. Depending on the shear rate, nonideal shear thinning and yield stress suspending fluids might show elasticity that needs to be taken into account. The flow field around one particle is studied in different fluids when subjected to shear. Then using these results to explain the two particle interactions in a simple-shear flow we show how particle-particle contact and non-Newtonian behaviors result in relative trajectories with fore-aft asymmetry. Well-resolved velocity and stress fields around the particles are presented here. Finally, we discuss how the relative particle trajectories may affect the microstructure of complex suspensions and consequently the bulk rheology. NSF (Grant No. CBET-1554044-CAREER).

Dynamic Transitions and Baroclinic Instability for 3D Continuously Stratified Boussinesq Flows

NASA Astrophysics Data System (ADS)

Şengül, Taylan; Wang, Shouhong

2018-02-01

The main objective of this article is to study the nonlinear stability and dynamic transitions of the basic (zonal) shear flows for the three-dimensional continuously stratified rotating Boussinesq model. The model equations are fundamental equations in geophysical fluid dynamics, and dynamics associated with their basic zonal shear flows play a crucial role in understanding many important geophysical fluid dynamical processes, such as the meridional overturning oceanic circulation and the geophysical baroclinic instability. In this paper, first we derive a threshold for the energy stability of the basic shear flow, and obtain a criterion for local nonlinear stability in terms of the critical horizontal wavenumbers and the system parameters such as the Froude number, the Rossby number, the Prandtl number and the strength of the shear flow. Next, we demonstrate that the system always undergoes a dynamic transition from the basic shear flow to either a spatiotemporal oscillatory pattern or circle of steady states, as the shear strength of the basic flow crosses a critical threshold. Also, we show that the dynamic transition can be either continuous or catastrophic, and is dictated by the sign of a transition number, fully characterizing the nonlinear interactions of different modes. Both the critical shear strength and the transition number are functions of the system parameters. A systematic numerical method is carried out to explore transition in different flow parameter regimes. In particular, our numerical investigations show the existence of a hypersurface which separates the parameter space into regions where the basic shear flow is stable and unstable. Numerical investigations also yield that the selection of horizontal wave indices is determined only by the aspect ratio of the box. We find that the system admits only critical eigenmodes with roll patterns aligned with the x-axis. Furthermore, numerically we encountered continuous transitions to multiple steady states, as well as continuous and catastrophic transitions to spatiotemporal oscillations.

Population splitting of rodlike swimmers in Couette flow.

PubMed

Nili, Hossein; Kheyri, Masoud; Abazari, Javad; Fahimniya, Ali; Naji, Ali

2017-06-28

We present a quantitative analysis on the response of a dilute active suspension of self-propelled rods (swimmers) in a planar channel subjected to an imposed shear flow. To best capture the salient features of the shear-induced effects, we consider the case of an imposed Couette flow, providing a constant shear rate across the channel. We argue that the steady-state behavior of swimmers can be understood in the light of a population splitting phenomenon, occurring as the shear rate exceeds a certain threshold, initiating the reversal of the swimming direction for a finite fraction of swimmers from down- to upstream or vice versa, depending on the swimmer position within the channel. Swimmers thus split into two distinct, statistically significant and oppositely swimming majority and minority populations. The onset of population splitting translates into a transition from a self-propulsion-dominated regime to a shear-dominated regime, corresponding to a unimodal-to-bimodal change in the probability distribution function of the swimmer orientation. We present a phase diagram in terms of the swim and flow Péclet numbers showing the separation of these two regimes by a discontinuous transition line. Our results shed further light on the behavior of swimmers in a shear flow and provide an explanation for the previously reported non-monotonic behavior of the mean, near-wall, parallel-to-flow orientation of swimmers with increasing shear strength.

Suppression of thermally excited capillary waves by shear flow.

PubMed

Derks, Didi; Aarts, Dirk G A L; Bonn, Daniel; Lekkerkerker, Henk N W; Imhof, Arnout

2006-07-21

We investigate the thermal fluctuations of the colloidal gas-liquid interface subjected to a shear flow parallel to the interface. Strikingly, we find that the shear strongly suppresses capillary waves, making the interface smoother. This phenomenon can be described by introducing an effective interfacial tension that increases with the shear rate. The increase of sigma(eff) is a direct consequence of the loss of interfacial entropy caused by the flow, which affects especially the slow fluctuations. This demonstrates that the interfacial tension of fluids results from an intrinsic as well as a fluctuation contribution.

Shear-induced intracellular loading of cells with molecules by controlled microfluidics.

PubMed

Hallow, Daniel M; Seeger, Richard A; Kamaev, Pavel P; Prado, Gustavo R; LaPlaca, Michelle C; Prausnitz, Mark R

2008-03-01

This study tested the hypothesis that controlled flow through microchannels can cause shear-induced intracellular loading of cells with molecules. The overall goal was to design a simple device to expose cells to fluid shear stress and thereby increase plasma membrane permeability. DU145 prostate cancer cells were exposed to fluid shear stress in the presence of fluorescent cell-impermeant molecules by using a cone-and-plate shearing device or high-velocity flow through microchannels. Using a syringe pump, cell suspensions were flowed through microchannels of 50-300 microm diameter drilled through Mylar sheets using an excimer laser. As quantified by flow cytometry, intracellular uptake and loss of viability correlated with the average shear stress. Optimal results were observed when exposing the cells to high shear stress for short durations in conical channels, which yielded uptake to over one-third of cells while maintaining viability at approximately 80%. This method was capable of loading cells with molecules including calcein (0.62 kDa), large molecule weight dextrans (150-2,000 kDa), and bovine serum albumin (66 kDa). These results supported the hypothesis that shear-induced intracellular uptake could be generated by flow of cell suspensions through microchannels and further led to the design of a simple, inexpensive, and effective device to deliver molecules into cells. Such a device could benefit biological research and the biotechnology industry. Copyright 2007 Wiley Periodicals, Inc.

Shear-induced intracellular loading of cells with molecules by controlled microfluidics

PubMed Central

Hallow, Daniel M.; Seeger, Richard A.; Kamaev, Pavel P.; Prado, Gustavo R.; LaPlaca, Michelle C.; Prausnitz, Mark R.

2010-01-01

This study tested the hypothesis that controlled flow through microchannels can cause shear-induced intracellular loading of cells with molecules. The overall goal was to design a simple device to expose cells to fluid shear stress and thereby increase plasma membrane permeability. DU145 prostate cancer cells were exposed to fluid shear stress in the presence of fluorescent cell-impermeant molecules by using a cone-and-plate shearing device or high-velocity flow through microchannels. Using a syringe pump, cell suspensions were flowed through microchannels of 50 – 300 μm diameter drilled through Mylar® sheets using an excimer laser. As quantified by flow cytometry, intracellular uptake and loss of viability correlated with the average shear stress. Optimal results were observed when exposing the cells to high shear stress for short durations in conical channels, which yielded uptake to over one third of cells while maintaining viability at approximately 80%. This method was capable of loading cells with molecules including calcein (0.62 kDa), large molecule weight dextrans (150 - 2000 kDa), and bovine serum albumin (66 kDa). These results supported the hypothesis that shear-induced intracellular uptake could be generated by flow of cell suspensions through microchannels and further led to the design of a simple, inexpensive, and effective device to deliver molecules into cells. Such a device could benefit biological research and the biotechnology industry. PMID:17879304

Coherent synchrotron radiation for laminar flows

NASA Astrophysics Data System (ADS)

Schmekel, Bjoern S.; Lovelace, Richard V. E.

2006-11-01

We investigate the effect of shear in the flow of charged particle equilibria that are unstable to the coherent synchrotron radiation (CSR) instability. Shear may act to quench this instability because it acts to limit the size of the region with a fixed phase relation between emitters. The results are important for the understanding of astrophysical sources of coherent radiation where shear in the flow is likely.

E × B flow shear drive of the linear low- n modes of EHO in the QH-mode regime [ E × B flow shear drive of EHO in the QH-mode regime

DOE Office of Scientific and Technical Information (OSTI.GOV)

Xu, G. S.; Wan, B. N.; Wang, Y. F.

A new mechanism is identified for driving the edge harmonic oscillations (EHOs) in the quiescent H-mode (QH-mode) regime, where a strong E × B flow shear destabilizes low-n kink/peeling modes, separately from the previously found Kelvin-Helmholtz drive. We find that the differential advection of mode vorticity by sheared E × B flows modifies the two-dimensional pattern of mode electrostatic potential perpendicular to the magnetic field lines, which in turn causes a radial expansion of the mode structure, an increase of field line bending away from the mode rational surface, and a reduction of inertial stabilization. This enhances the kink drivemore » as the parallel wavenumber increases significantly away from the rational surface where the magnetic shear is also strong. A newly developed model reproduces the observations that at high E × B flow shear only a few low-n modes remain unstable, consistent with the EHO behavior, while at low E × B flow shear the unstable mode spectrum is significantly broadened, consistent with the low-n broadband electromagnetic turbulence behavior observed recently in the DIII-D tokamak. This destabilization is also shown to be independent of the sign of the flow shear, as observed experimentally, and has not been taken into 2 / 46 account in previous pedestal linear stability analyses. Verification of the veracity of this EHO mechanism will require analysis of the nonlinear evolution of low-n kink/peeling modes so destabilized in the linear regime.« less

E × B flow shear drive of the linear low- n modes of EHO in the QH-mode regime [ E × B flow shear drive of EHO in the QH-mode regime

DOE PAGES

Xu, G. S.; Wan, B. N.; Wang, Y. F.; ...

2017-07-18

A new mechanism is identified for driving the edge harmonic oscillations (EHOs) in the quiescent H-mode (QH-mode) regime, where a strong E × B flow shear destabilizes low-n kink/peeling modes, separately from the previously found Kelvin-Helmholtz drive. We find that the differential advection of mode vorticity by sheared E × B flows modifies the two-dimensional pattern of mode electrostatic potential perpendicular to the magnetic field lines, which in turn causes a radial expansion of the mode structure, an increase of field line bending away from the mode rational surface, and a reduction of inertial stabilization. This enhances the kink drivemore » as the parallel wavenumber increases significantly away from the rational surface where the magnetic shear is also strong. A newly developed model reproduces the observations that at high E × B flow shear only a few low-n modes remain unstable, consistent with the EHO behavior, while at low E × B flow shear the unstable mode spectrum is significantly broadened, consistent with the low-n broadband electromagnetic turbulence behavior observed recently in the DIII-D tokamak. This destabilization is also shown to be independent of the sign of the flow shear, as observed experimentally, and has not been taken into 2 / 46 account in previous pedestal linear stability analyses. Verification of the veracity of this EHO mechanism will require analysis of the nonlinear evolution of low-n kink/peeling modes so destabilized in the linear regime.« less

Animal models of surgically manipulated flow velocities to study shear stress-induced atherosclerosis.

PubMed

Winkel, Leah C; Hoogendoorn, Ayla; Xing, Ruoyu; Wentzel, Jolanda J; Van der Heiden, Kim

2015-07-01

Atherosclerosis is a chronic inflammatory disease of the arterial tree that develops at predisposed sites, coinciding with locations that are exposed to low or oscillating shear stress. Manipulating flow velocity, and concomitantly shear stress, has proven adequate to promote endothelial activation and subsequent plaque formation in animals. In this article, we will give an overview of the animal models that have been designed to study the causal relationship between shear stress and atherosclerosis by surgically manipulating blood flow velocity profiles. These surgically manipulated models include arteriovenous fistulas, vascular grafts, arterial ligation, and perivascular devices. We review these models of manipulated blood flow velocity from an engineering and biological perspective, focusing on the shear stress profiles they induce and the vascular pathology that is observed. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

Microstructural Rearrangements and their Rheological Implications in a Model Thixotropic Elastoviscoplastic Fluid

NASA Astrophysics Data System (ADS)

Jamali, Safa; McKinley, Gareth H.; Armstrong, Robert C.

2017-01-01

We identify the sequence of microstructural changes that characterize the evolution of an attractive particulate gel under flow and discuss their implications on macroscopic rheology. Dissipative particle dynamics is used to monitor shear-driven evolution of a fabric tensor constructed from the ensemble spatial configuration of individual attractive constituents within the gel. By decomposing this tensor into isotropic and nonisotropic components we show that the average coordination number correlates directly with the flow curve of the shear stress versus shear rate, consistent with theoretical predictions for attractive systems. We show that the evolution in nonisotropic local particle rearrangements are primarily responsible for stress overshoots (strain-hardening) at the inception of steady shear flow and also lead, at larger times and longer scales, to microstructural localization phenomena such as shear banding flow-induced structure formation in the vorticity direction.

Tracing the Pathway from Drift-Wave Turbulence with Broken Symmetry to the Production of Sheared Axial Mean Flow

NASA Astrophysics Data System (ADS)

Hong, R.; Li, J. C.; Chakraborty Thakur, S.; Hajjar, R.; Diamond, P. H.; Tynan, G. R.

2018-05-01

This study traces the emergence of sheared axial flow from collisional drift-wave turbulence with broken symmetry in a linear plasma device—the controlled shear decorrelation experiment. As the density profile steepens, the axial Reynolds stress develops and drives a radially sheared axial flow that is parallel to the magnetic field. Results show that the nondiffusive piece of the Reynolds stress is driven by the density gradient, results from spectral asymmetry of the turbulence, and, thus, is dynamical in origin. Taken together, these findings constitute the first simultaneous demonstration of the causal link between the density gradient, turbulence, and stress with broken spectral symmetry and the mean axial flow.

Streamline curvature in supersonic shear layers

NASA Technical Reports Server (NTRS)

Kibens, V.

1992-01-01

Results of an experimental investigation in which a curved shear layer was generated between supersonic flow from a rectangular converging/diverging nozzle and the freestream in a series of open channels with varying radii of curvature are reported. The shear layers exhibit unsteady large-scale activity at supersonic pressure ratios, indicating increased mixing efficiency. This effect contrasts with supersonic flow in a straight channel, for which no large-scale vortical structure development occurs. Curvature must exceed a minimum level before it begins to affect the dynamics of the supersonic shear layer appreciably. The curved channel flows are compared with reference flows consisting of a free jet, a straight channel, and wall jets without sidewalls on a flat and a curved plate.

Observations of reduced electron Gyroscale fluctuations in national spherical torus experiment H-mode plasmas with large ExB flow shear.

PubMed

Smith, D R; Kaye, S M; Lee, W; Mazzucato, E; Park, H K; Bell, R E; Domier, C W; Leblanc, B P; Levinton, F M; Luhmann, N C; Menard, J E; Yuh, H

2009-06-05

Electron gyroscale fluctuation measurements in National Spherical Torus Experiment H-mode plasmas with large toroidal rotation reveal fluctuations consistent with electron temperature gradient (ETG) turbulence. Large toroidal rotation in National Spherical Torus Experiment plasmas with neutral beam injection generates ExB flow shear rates comparable to ETG linear growth rates. Enhanced fluctuations occur when the electron temperature gradient is marginally stable with respect to the ETG linear critical gradient. Fluctuation amplitudes decrease when the ExB flow shear rate exceeds ETG linear growth rates. The observations indicate that ExB flow shear can be an effective suppression mechanism for ETG turbulence.

Shear-Induced Amyloid Formation in the Brain: I. Potential Vascular and Parenchymal Processes.

PubMed

Trumbore, Conrad N

2016-09-06

Shear distortion of amyloid-beta (Aβ) solutions accelerates amyloid cascade reactions that may yield different toxic oligomers than those formed in quiescent solutions. Recent experiments indicate that cerebrospinal fluid (CSF) and interstitial fluid (ISF) containing Aβ flow through narrow brain perivascular pathways and brain parenchyma. This paper suggests that such flow causes shear distortion of Aβ molecules involving conformation changes that may be one of the initiating events in the etiology of Alzheimer's disease. Aβ shearing can occur in or around brain arteries and arterioles and is suggested as the origin of cerebral amyloid angiopathy deposits in cerebrovascular walls. Comparatively low flow rates of ISF within the narrow extracellular spaces (ECS) of the brain parenchyma are suggested as a possible initiating factor in both the formation of neurotoxic Aβ42 oligomers and amyloid fibrils. Aβ42 in slow-flowing ISF can gain significant shear energy at or near the walls of tortuous brain ECS flow paths, promoting the formation of a shear-distorted, excited state hydrophobic Aβ42* conformation. This Aβ42* molecule could possibly be involved in one of two paths, one involving rapid adsorption to a brain membrane surface, ultimately forming neurotoxic oligomers on membranes, and the other ultimately forming plaque within the ECS flow pathways. Rising Aβ concentrations combined with shear at or near critical brain membranes are proposed as contributing factors to Alzheimer's disease neurotoxicity. These hypotheses may be applicable in other neurodegenerative diseases, including tauopathies and alpha-synucleinopathies, in which shear-distorted proteins also may form in the brain ECS.

Effects of Coating Materials and Processing Conditions on Flow Enhancement of Cohesive Acetaminophen Powders by High-Shear Processing With Pharmaceutical Lubricants.

PubMed

Wei, Guoguang; Mangal, Sharad; Denman, John; Gengenbach, Thomas; Lee Bonar, Kevin; Khan, Rubayat I; Qu, Li; Li, Tonglei; Zhou, Qi Tony

2017-10-01

This study has investigated the surface coating efficiency and powder flow improvement of a model cohesive acetaminophen powder by high-shear processing with pharmaceutical lubricants through 2 common equipment, conical comil and high-shear mixer. Effects of coating materials and processing parameters on powder flow and surface coating coverage were evaluated. Both Carr's index and shear cell data indicated that processing with the lubricants using comil or high-shear mixer substantially improved the flow of the cohesive acetaminophen powder. Flow improvement was most pronounced for those processed with 1% wt/wt magnesium stearate, from "cohesive" for the V-blended sample to "easy flowing" for the optimally coated sample. Qualitative and quantitative characterizations demonstrated a greater degree of surface coverage for high-shear mixing compared with comilling; nevertheless, flow properties of the samples at the corresponding optimized conditions were comparable between 2 techniques. Scanning electron microscopy images demonstrated different coating mechanisms with magnesium stearate or l-leucine (magnesium stearate forms a coating layer and leucine coating increases surface roughness). Furthermore, surface coating with hydrophobic magnesium stearate did not retard the dissolution kinetics of acetaminophen. Future studies are warranted to evaluate tableting behavior of such dry-coated pharmaceutical powders. Copyright © 2017 American Pharmacists Association®. Published by Elsevier Inc. All rights reserved.

Shear dispersion in dense granular flows

DOE PAGES

Christov, Ivan C.; Stone, Howard A.

2014-04-18

We formulate and solve a model problem of dispersion of dense granular materials in rapid shear flow down an incline. The effective dispersivity of the depth-averaged concentration of the dispersing powder is shown to vary as the Péclet number squared, as in classical Taylor–Aris dispersion of molecular solutes. An extension to generic shear profiles is presented, and possible applications to industrial and geological granular flows are noted.

Mantle Flow in the Western United States Constrained by Seismic Anisotropy

NASA Astrophysics Data System (ADS)

Niday, W.; Humphreys, E.

2017-12-01

Shear wave splitting, caused by the lattice preferred orientation (LPO) of olivine crystals under shear deformation, provide a useful constraint on numerical models of mantle flow. Although it is sometimes assumed that shear wave splitting fast directions correspond with mantle flow directions, this is only true in simple shear flows that do not vary strongly with space or time. Observed shear wave splitting in the western United States is complex and inconsistent with simple shear driven by North American and Pacific plate motion, suggesting that the effects of time-dependent subduction history and spatial heterogeneity are important. Liu and Stegman (2011) reproduce the pattern of fast seismic anomalies below the western US from Farallon subduction history, and Chaparro and Stegman (2017) reproduce the circular anisotropy field below the Great Basin. We extend this to consider anisotropic structure outside the Great Basin and evaluate the density and viscosity of seismic anomalies such as slabs and Yellowstone. We use the mantle convection code ASPECT to simulate 3D buoyancy-driven flow in the mantle below the western US, and predict LPO using the modeled flow fields. We present results from a suite of models varying the sub-lithospheric structures of the western US and constraints on density and viscosity variations in the upper mantle.

Rheological Characterisation of the Flow Behaviour of Wood Plastic Composites in Consideration of Different Volume Fractions of Wood

NASA Astrophysics Data System (ADS)

Laufer, N.; Hansmann, H.; Koch, M.

2017-01-01

In this study, the rheological properties of wood plastic composites (WPC) with different polymeric matrices (LDPE, low-density polyethylene and PP, polypropylene) and with different types of wood filler (hardwood flour and softwood flour) have been investigated by means of high pressure capillary rheometry. The volume fraction of wood was varied between 0 and 60 %. The shear thinning behaviour of the WPC melts can be well described by the Ostwald - de Waele power law relationship. The flow consistency index K of the power law shows a good correlation with the volume fraction of wood. Interparticular interaction effects of wood particles can be mathematically taken into account by implementation of an interaction exponent (defined as the ratio between flow exponent of WPC and flow exponent of polymeric matrix). The interaction exponent shows a good correlation with the flow consistency index. On the basis of these relationships the concept of shear-stress-equivalent inner shear rate has been modified. Thus, the flow behaviour of the investigated wood filled polymer melts could be well described mathematically by the modified concept of shear-stress-equivalent inner shear rate. On this basis, the shear thinning behaviour of WPC can now be estimated with good accuracy, taking into account the volume fraction of wood.

An integral turbulent kinetic energy analysis of free shear flows

NASA Technical Reports Server (NTRS)

Peters, C. E.; Phares, W. J.

1973-01-01

Mixing of coaxial streams is analyzed by application of integral techniques. An integrated turbulent kinetic energy (TKE) equation is solved simultaneously with the integral equations for the mean flow. Normalized TKE profile shapes are obtained from incompressible jet and shear layer experiments and are assumed to be applicable to all free turbulent flows. The shear stress at the midpoint of the mixing zone is assumed to be directly proportional to the local TKE, and dissipation is treated with a generalization of the model developed for isotropic turbulence. Although the analysis was developed for ducted flows, constant-pressure flows were approximated with the duct much larger than the jet. The axisymmetric flows under consideration were predicted with reasonable accuracy. Fairly good results were also obtained for the fully developed two-dimensional shear layers, which were computed as thin layers at the boundary of a large circular jet.

Precessing rotating flows with additional shear: stability analysis.

PubMed

Salhi, A; Cambon, C

2009-03-01

We consider unbounded precessing rotating flows in which vertical or horizontal shear is induced by the interaction between the solid-body rotation (with angular velocity Omega(0)) and the additional "precessing" Coriolis force (with angular velocity -epsilonOmega(0)), normal to it. A "weak" shear flow, with rate 2epsilon of the same order of the Poincaré "small" ratio epsilon , is needed for balancing the gyroscopic torque, so that the whole flow satisfies Euler's equations in the precessing frame (the so-called admissibility conditions). The base flow case with vertical shear (its cross-gradient direction is aligned with the main angular velocity) corresponds to Mahalov's [Phys. Fluids A 5, 891 (1993)] precessing infinite cylinder base flow (ignoring boundary conditions), while the base flow case with horizontal shear (its cross-gradient direction is normal to both main and precessing angular velocities) corresponds to the unbounded precessing rotating shear flow considered by Kerswell [Geophys. Astrophys. Fluid Dyn. 72, 107 (1993)]. We show that both these base flows satisfy the admissibility conditions and can support disturbances in terms of advected Fourier modes. Because the admissibility conditions cannot select one case with respect to the other, a more physical derivation is sought: Both flows are deduced from Poincaré's [Bull. Astron. 27, 321 (1910)] basic state of a precessing spheroidal container, in the limit of small epsilon . A Rapid distortion theory (RDT) type of stability analysis is then performed for the previously mentioned disturbances, for both base flows. The stability analysis of the Kerswell base flow, using Floquet's theory, is recovered, and its counterpart for the Mahalov base flow is presented. Typical growth rates are found to be the same for both flows at very small epsilon , but significant differences are obtained regarding growth rates and widths of instability bands, if larger epsilon values, up to 0.2, are considered. Finally, both flow cases are briefly discussed in view of a subsequent nonlinear study using pseudospectral direct numerical simulations, which is a natural continuation of RDT.

The Role of Fine Sediment Content on Soil Consolidation and Debris Flows Development after Earthquake

NASA Astrophysics Data System (ADS)

Lyu, L.; Xu, M., III; Wang, Z.

2017-12-01

Fine sediment has been identified as an important factor determining the critical runoff that initiates debris flows because its contribution to shear strength through consolidation. Especially, owing to the 2008 Wenchuan earthquake in China enormous of loose sediment with different fractions of fine particles was eroded and supplied as materials for debris flows. The loose materials are gradually consolidated along with time, and therefore stronger rainfall is required to overcome the shear strength and to initiate debris flows. In this study, flume experiments were performed to explore soil consolidation and shear strength on mass failure and debris flow initiation under the conditions that different fractions of fine sediment were contained in the materials. Under the low content of fine sediment conditions (mass percentages: 0-10%), the debris flows formed with large pores and low shear strength and thus fine particles were too few to fill up the pores among the coarse particles. The consolidation rate was mostly influenced by the content of the fine particles. Consolidation of fine particles caused an increase of the shear strength and decrease of the rainfall infiltration, and therefore, debris flow initiation required stronger rainfall as the consolidation of the fine particles developed.

Jetting of a shear banding fluid in rectangular ducts

PubMed Central

Salipante, Paul F.; Little, Charles A. E.; Hudson, Steven D.

2017-01-01

Non-Newtonian fluids are susceptible to flow instabilities such as shear banding, in which the fluid may exhibit a markedly discontinuous viscosity at a critical stress. Here we report the characteristics and causes of a jetting flow instability of shear banding wormlike micelle solutions in microfluidic channels with rectangular cross sections over an intermediate volumetric flow regime. Particle-tracking methods are used to measure the three-dimensional flow field in channels of differing aspect ratios, sizes, and wall materials. When jetting occurs, it is self-contained within a portion of the channel where the flow velocity is greater than the surroundings. We observe that the instability forms in channels with aspect ratio greater than 5, and that the location of the high-velocity jet appears to be sensitive to stress localizations. Jetting is not observed in a lower concentration solution without shear banding. Simulations using the Johnson-Segalman viscoelastic model show a qualitatively similar behavior to the experimental observations and indicate that compressive normal stresses in the cross-stream directions support the development of the jetting flow. Our results show that nonuniform flow of shear thinning fluids can develop across the wide dimension in rectangular microfluidic channels, with implications for microfluidic rheometry. PMID:28691108

Increasing Plasma Parameters using Sheared Flow Stabilization of a Z-Pinch

NASA Astrophysics Data System (ADS)

Shumlak, Uri

2016-10-01

Recent experiments on the ZaP Flow Z-Pinch at the University of Washington have been successful in compressing the plasma column to smaller radii, producing the predicted increases in plasma density (1018 cm-3), temperature (200 eV), and magnetic fields (4 T), while maintaining plasma stability for many Alfven times (over 40 μs) using sheared plasma flows. These results indicate the suitability of the device as a discovery science platform for astrophysical and high energy density plasma research, and keeps open a possible path to achieving burning plasma conditions in a compact fusion device. Long-lived Z-pinch plasmas have been produced with dimensions of 1 cm radius and 100 cm long that are stabilized by sheared axial flows for over 1000 Alfven radial transit times. The observed plasma stability is coincident with the presence of a sheared flow as measured by time-resolved multi-chord ion Doppler spectroscopy applied to impurity ion radiation. These measurements yield insights into the evolution of the velocity profile and show that the stabilizing behavior of flow shear agrees with theoretical calculations and 2-D MHD computational simulations. The flow shear value, extent, and duration are shown to be consistent with theoretical models of the plasma viscosity, which places a design constraint on the maximum axial length of a sheared flow stabilized Z-pinch. Measurements of the magnetic field topology indicate simultaneous azimuthal symmetry and axial uniformity along the entire 100 cm length of the Z-pinch plasma. Separate control of plasma acceleration and compression have increased the accessible plasma parameters and have generated stable plasmas with radii below 0.5 cm, as measured with a high resolution digital holographic interferometer. This work was supported by Grants from U.S. DOE, NNSA, and ARPA-E.

Linear Instability of a Uni-Directional Transversely Sheared Mean Flow

NASA Technical Reports Server (NTRS)

Wundrow, David W.

1996-01-01

The effect of spanwise-periodic mean-flow distortions (i.e. streamwise-vortex structures) on the evolution of small-amplitude, single-frequency instability waves in an otherwise two-dimensional shear flow is investigated. The streamwise-vortex structures are taken to be just weak enough so that the spatially growing instability waves behave (locally) like linear perturbations about a uni-directional transversely sheared mean flow. Numerical solutions are computed and discussed for both the mean flow and the instability waves. The influence of the streamwise-vortex wavelength on the properties of the most rapidly growing instability wave is also discussed.

Flow and wall shear stress characterization after endovascular aneurysm repair and endovascular aneurysm sealing in an infrarenal aneurysm model.

PubMed

Boersen, Johannes T; Groot Jebbink, Erik; Versluis, Michel; Slump, Cornelis H; Ku, David N; de Vries, Jean-Paul P M; Reijnen, Michel M P J

2017-12-01

Endovascular aneurysm repair (EVAR) with a modular endograft has become the preferred treatment for abdominal aortic aneurysms. A novel concept is endovascular aneurysm sealing (EVAS), consisting of dual endoframes surrounded by polymer-filled endobags. This dual-lumen configuration is different from a bifurcation with a tapered trajectory of the flow lumen into the two limbs and may induce unfavorable flow conditions. These include low and oscillatory wall shear stress (WSS), linked to atherosclerosis, and high shear rates that may result in thrombosis. An in vitro study was performed to assess the impact of EVAR and EVAS on flow patterns and WSS. Four abdominal aortic aneurysm phantoms were constructed, including three stented models, to study the influence of the flow divider on flow (Endurant [Medtronic, Minneapolis, Minn], AFX [Endologix, Irvine, Calif], and Nellix [Endologix]). Experimental models were tested under physiologic resting conditions, and flow was visualized with laser particle imaging velocimetry, quantified by shear rate, WSS, and oscillatory shear index (OSI) in the suprarenal aorta, renal artery (RA), and common iliac artery. WSS and OSI were comparable for all models in the suprarenal aorta. The RA flow profile in the EVAR models was comparable to the control, but a region of lower WSS was observed on the caudal wall compared with the control. The EVAS model showed a stronger jet flow with a higher shear rate in some regions compared with the other models. Small regions of low WSS and high OSI were found near the distal end of all stents in the common iliac artery compared with the control. Maximum shear rates in each region of interest were well below the pathologic threshold for acute thrombosis. The different stent designs do not influence suprarenal flow. Lower WSS is observed in the caudal wall of the RA after EVAR and a higher shear rate after EVAS. All stented models have a small region of low WSS and high OSI near the distal outflow of the stents. Copyright © 2016 Society for Vascular Surgery. Published by Elsevier Inc. All rights reserved.

Origin of leucite-rich and sanidine-rich flow layers in the Leucite Hills Volcanic Field, Wyoming

NASA Astrophysics Data System (ADS)

Gunter, W. D.; Hoinkes, Georg; Ogden, Palmer; Pajari, G. E.

1990-09-01

Two types of orendite (sanidine-phlogopite lamproite) and wyomingite (leucite-phlogopite lamproite) intraflow layering are present in the ultrapotassic Leucite Hills Volcanic Field, Wyoming. In large-scale layering, wyomingites are confined to the base of the flow, while in centimeter-scale layering, orendite and wyomingite alternate throughout the flow. The mineralogy of the orendites and wyomingites are the same; only the relative amount of each mineral vary substantially. The chemical compositions of adjacent layers of wyomingite and orendite are almost identical except for water. The centimeter-scale flow layering probably represents fossil streamlines of the lava and therefore defines the path of circulation of the viscous melt. Toward the front of the flow, the layers are commonly folded. Structures present which are indicative that the flows may have possessed a yield strength are limb shears, boudinage, and slumping. Phlogopite phenocrysts are poorly aligned in the orendite layers, while they are often in subparallel alignment in the wyomingite layers; and they are used as a measure of shearing intensity during emplacement of the flow. Vesicle volumes are concentrated in the orendite layers. In the large-scale layering, a discontinuous base rubble zone of autobreccia is overlain by a thin platy zone followed by a massive zone which composes more than the upper 75% of the flow. Consequently, we feel that the origin of the layering may be related to shearing. Two extremes in the geometry of shearing are proposed: closely spaced, thin, densely sheared layers separated by discrete intervals throughout a lava flow as in the centimeter-scale layering and classical plug flow where all the shearing is confined to the base as in the large-scale layering. A mechanism is proposed which causes thixotropic behavior and localizes shearing: the driving force is the breakdown of molecular water to form T-OH bonds which establishes a chemical potential gradient for water in the melt. The higher activity of water in the nonsheared regions allows sandine to crystallize, whereas the lower activity of water in the areas of active shearing causes leucite to crystallize.

The high-energy-density counterpropagating shear experiment and turbulent self-heating

DOE PAGES

Doss, F. W.; Fincke, J. R.; Loomis, E. N.; ...

2013-12-06

The counterpropagating shear experiment has previously demonstrated the ability to create regions of shockdriven shear, balanced symmetrically in pressure and experiencing minimal net drift. This allows for the creation of a high-Mach-number high-energy-density shear environment. New data from the counterpropagating shear campaign is presented, and both hydrocode modeling and theoretical analysis in the context of a Reynolds-averaged-Navier-Stokes model suggest turbulent dissipation of energy from the supersonic flow bounding the layer is a significant driver in its expansion. A theoretical minimum shear flow Mach number threshold is suggested for substantial thermal-turbulence coupling.

Rapid distortion analysis of high speed homogeneous turbulence subject to periodic shear

DOE PAGES

Bertsch, Rebecca L.; Girimaji, Sharath S.

2015-12-30

The effect of unsteady shear forcing on small perturbation growth in compressible flow is investigated. In particular, flow-thermodynamic field interaction and the resulting effect on the phase-lag between applied shear and Reynolds stress are examined. Simplified linear analysis of the perturbation pressure equation reveals crucial differences between steady and unsteady shear effects. The analytical findings are validated with numerical simulations of inviscid rapid distortion theory (RDT) equations. In contrast to steadily sheared compressible flows, perturbations in the unsteady (periodic) forcing case do not experience an asymptotic growth phase. Further, the resonance growth phenomenon found in incompressible unsteady shear turbulence ismore » absent in the compressible case. Overall, the stabilizing influence of both unsteadiness and compressibility is compounded leading to suppression of all small perturbations. As a result, the underlying mechanisms are explained.« less

Rapid distortion analysis of high speed homogeneous turbulence subject to periodic shear

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bertsch, Rebecca L., E-mail: rlb@lanl.gov; Girimaji, Sharath S., E-mail: girimaji@aero.tamu.edu

2015-12-15

The effect of unsteady shear forcing on small perturbation growth in compressible flow is investigated. In particular, flow-thermodynamic field interaction and the resulting effect on the phase-lag between applied shear and Reynolds stress are examined. Simplified linear analysis of the perturbation pressure equation reveals crucial differences between steady and unsteady shear effects. The analytical findings are validated with numerical simulations of inviscid rapid distortion theory (RDT) equations. In contrast to steadily sheared compressible flows, perturbations in the unsteady (periodic) forcing case do not experience an asymptotic growth phase. Further, the resonance growth phenomenon found in incompressible unsteady shear turbulence ismore » absent in the compressible case. Overall, the stabilizing influence of both unsteadiness and compressibility is compounded leading to suppression of all small perturbations. The underlying mechanisms are explained.« less

Consequences of viscous anisotropy for melt localization in a deforming, two-phase aggregate

NASA Astrophysics Data System (ADS)

Takei, Y.; Katz, R. F.

2012-12-01

Melt localization in the deforming, partially molten mantle has been of interest because it affects the melt extraction rate, mantle deformability, and chemical interaction between the melt and host rock. Experimental studies have reported the spontaneous segregation of melt into melt-rich bands in samples deformed under simple shear and torsion (Holtzman et al, 2003, King et al, 2010). Efforts to clarify the instability mechanism have so far revealed that rheological properties of partially molten rocks control the occurrence of instability. Porosity-weakening viscosity, empirically written as exp(- λ × f) with porosity f and constant λ(= 25-45), plays an essential role in the destabilization of porosity perturbation in the shear flow of a two-phase aggregate (eg., pure shear flow, simple shear flow): the perturbation growth rate is proportional to the product of shear strain rate and the factor λ (Stevenson, 1989). The stress exponent n of the viscosity affects the angle of the perturbation plane with maximum growthrate, where n=3-6 (power-law creep) explains the experimentally observed low angle to the shear plane (Katz et al, 2006). However, in-situ experimental measurements of n indicate that it takes values as low as unity without affecting the observed orientation of melt bands. Viscous anisotropy provides an alternative explanation for the observed band angles. It is produced by the stress-induced microstructural anisotropy (Daines and Kohlstedt, 1997; Zimmermann et al., 1999; Takei, 2010), and it enhances the coupling between melt migration and matrix shear deformation (Takei and Holtzman, 2009). Even without any porosity perturbation, viscous anisotropy destabilizes simple patterns of two-phase flow with a stress/strain gradient (eg., Poiseuille flow, torsional flow) and gives rise to shear-induced melt localization: the growth rate of this mechanism depends on the shear strain rate and the compaction length relative to the spatial scale of the gradient. When a porosity perturbation is added to the anisotropic system, both localization mechanisms work simultaneously, where the dominant angle of perturbation is decreased by the viscous anisotropy, similarly to the effect of n. Although viscous anisotropy plays an important role in melt localization, previous studies were limited to some simple or linearized cases (Takei and Holtzman, 2009, Butler 2012). Using linearised stability analysis and numerical simulation, we perform a systematic study of viscous anisotropy for behavior of partially molten rocks under forced deformation. Fully nonlinear solutions are obtained for melt localization under simple shear flow, 2D Poiseuille flow, and torsional flow. We show that Poiseuille flow causes melt-lubrication instability, but torsional flow does not. Results for simple shear and torsional flow are compared to the experimental results. Through the comparison between model predictions and experiments, we can test the validity of current theory, ascertain its deficiencies, and refine it to better describe the natural system.

Role of endothelium sensitivity to shear stress in noradrenaline-induced constriction of feline femoral arterial bed under constant flow and constant pressure perfusions.

PubMed

Kartamyshev, Sergey P; Balashov, Sergey A; Melkumyants, Arthur M

2007-01-01

The effect of shear stress at the endothelium in the attenuation of the noradrenaline-induced constriction of the femoral vascular bed perfused at a constant blood flow was investigated in 16 anesthetized cats. It is known that the adrenergic vasoconstriction of the femoral vascular bed is considerably greater at a constant pressure perfusion than at a constant blood flow. This difference may depend on the ability of the endothelium to relax smooth muscle in response to an increase in wall shear stress. Since the shear stress is directly related to the blood flow and inversely related to the third power of vessel diameter, vasoconstriction at a constant blood flow increases the wall shear stress that is the stimulus for smooth muscle relaxation opposing constriction. On the other hand, at a constant perfusion pressure, vasoconstriction is accompanied by a decrease in flow rate, which prevents a wall shear stress increase. To reveal the effect of endothelial sensitivity to shear stress, we compared noradrenaline-induced changes in total and proximal arterial resistances during perfusion of the hind limb at a constant blood flow and at a constant pressure in vessels with intact and injured endothelium. We found that in the endothelium-intact bed the same concentration of noradrenaline at a constant flow caused an increase in overall vascular peripheral resistance that was half as large as at a constant perfusion pressure. This difference is mainly confined to the proximal arterial vessels (arteries and large arterioles) whose resistance at a constant flow increased only 0.19 +/- 0.03 times compared to that at a constant pressure. The removal of the endothelium only slightly increased constrictor responses at the perfusion under a constant pressure (noradrenaline-induced increases of both overall and proximal arterial resistance augmented by 12%), while the responses of the proximal vessels at a constant flow became 4.7 +/- 0.4 times greater than in the endothelium-intact bed. A selective blockage of endothelium sensitivity to shear stress using a glutaraldehyde dimer augmented the constrictor responses of the proximal vessels at a constant flow 4.6-fold (+/-0.3), but had no significant effect on the responses at a constant pressure. These results are consistent with the conclusion that the difference in constrictor responses at constant flow and pressure perfusions depends mainly on the smooth muscle relaxation caused by increased wall shear stress. Copyright (c) 2007 S. Karger AG, Basel.

Self-organization in suspensions of end-functionalized semiflexible polymers under shear flow

NASA Astrophysics Data System (ADS)

Myung, Jin Suk; Winkler, Roland G.; Gompper, Gerhard

2015-12-01

The nonequilibrium dynamical behavior and structure formation of end-functionalized semiflexible polymer suspensions under flow are investigated by mesoscale hydrodynamic simulations. The hybrid simulation approach combines the multiparticle collision dynamics method for the fluid, which accounts for hydrodynamic interactions, with molecular dynamics simulations for the semiflexible polymers. In equilibrium, various kinds of scaffold-like network structures are observed, depending on polymer flexibility and end-attraction strength. We investigate the flow behavior of the polymer networks under shear and analyze their nonequilibrium structural and rheological properties. The scaffold structure breaks up and densified aggregates are formed at low shear rates, while the structural integrity is completely lost at high shear rates. We provide a detailed analysis of the shear- rate-dependent flow-induced structures. The studies provide a deeper understanding of the formation and deformation of network structures in complex materials.

Rate Dependence of Elementary Rearrangements and Spatiotemporal Correlations in the 3D Flow of Soft Solids

NASA Astrophysics Data System (ADS)

Vasisht, Vishwas V.; Dutta, Sudeep K.; Del Gado, Emanuela; Blair, Daniel L.

2018-01-01

We use a combination of confocal microscopy, rheology, and molecular dynamics simulations to investigate jammed emulsions under shear, by analyzing the 3D droplets rearrangements in the shear frame. Our quantitative analysis of local dynamics reveals elementary nonaffine rearrangements that underlie the onset of the flow at small strains. We find that the mechanism of unjamming and the upturn in the material flow curve are associated to a qualitative change in spatiotemporal correlations of such rearrangements with the applied shear rate. At high shear rates, droplet clusters follow coordinated, stringlike motion. Conversely, at low shear rates, the elementary nonaffine rearrangements exhibit longer-ranged correlations, with complex spatiotemporal patterns. The 3D microscopic details provide novel insights into the specific features of the material flow curve, common to a large class of technologically relevant soft disordered solids and new fundamental ingredients for constitutive models.

Unsteady behavior of a reattaching shear layer

NASA Technical Reports Server (NTRS)

Driver, D. M.; Seegmiller, H. L.; Marvin, J.

1983-01-01

A detailed investigation of the unsteadiness in a reattaching, turbulent shear layer is reported. Laser-Doppler velocimeter measurements were conditionally sampled on the basis of instantaneous flow direction near reattachment. Conditions of abnormally short reattachment and abnormally long reattachment were considered. Ensemble-averaging of measurements made during these conditions was used to obtain mean velocities and Rreynolds stresses. In the mean flow, conditional streamlines show a global change in flow pattern which correlates with wall-flow direction. This motion can loosely be described as a 'flapping' of the shear layer. Tuft probes show that the flow direction reversals occur quite randomly and are shortlived. Streses shown also vary with the change in flow pattern. Yet, the global'flapping' motion does not appear to contribute significantly to the stress in the flow. A second type of unsteady motion was identified. Spectral analysis of both wall static pressure and streamwise velocity shows that most of the energy in the flow resides in frequencies that are significantly lower than that of the turbulence. The dominant frequency is at a Strouhal number equal to 0.2, which is the characteristic frequency of roll-up and pairing of vortical structure seen in free shear layers. It is conjectured that the 'flapping' is a disorder of the roll-up and pairing process occurring in the shear layer.

Theory of ion Bernstein wave induced shear suppression of turbulence

NASA Astrophysics Data System (ADS)

Craddock, G. G.; Diamond, P. H.; Ono, M.; Biglari, H.

1994-06-01

The theory of radio frequency induced ion Bernstein wave- (IBW) driven shear flow in the edge is examined, with the goal of application of shear suppression of fluctuations. This work is motivated by the observed confinement improvement on IBW heated tokamaks [Phys. Fluids B 5, 241 (1993)], and by previous low-frequency work on RF-driven shear flows [Phys. Rev. Lett. 67, 1535 (1991)]. It is found that the poloidal shear flow is driven electrostatically by both Reynolds stress and a direct ion momentum source, analogous to the concepts of helicity injection and electron momentum input in current drive, respectively. Flow drive by the former does not necessarily require momentum input to the plasma to induce a shear flow. For IBW, the direct ion momentum can be represented by direct electron momentum input, and a charge separation induced stress that imparts little momentum to the plasma. The derived Er profile due to IBW predominantly points inward, with little possibility of direction change, unlike low-frequency Alfvénic RF drive. The profile scale is set by the edge density gradient and electron dissipation. Due to the electrostatic nature of ion Bernstein waves, the poloidal flow contribution dominates in Er. Finally, the necessary edge power absorbed for shear suppression on Princeton Beta Experiment-Modified (PBX-M) [9th Topical Conference on Radio Frequency Power in Plasmas, Charleston, SC, 1991 (American Institute of Physics, New York, 1991), p. 129] is estimated to be 100 kW distributed over 5 cm.

Turbulence significantly increases pressure and fluid shear stress in an aortic aneurysm model under resting and exercise flow conditions.

PubMed

Khanafer, Khalil M; Bull, Joseph L; Upchurch, Gilbert R; Berguer, Ramon

2007-01-01

The numerical models of abdominal aortic aneurysm (AAA) in use do not take into account the non-Newtonian behavior of blood and the development of local turbulence. This study examines the influence of pulsatile, turbulent, non-Newtonian flow on fluid shear stresses and pressure changes under rest and exercise conditions. We numerically analyzed pulsatile turbulent flow, using simulated physiological rest and exercise waveforms, in axisymmetric-rigid aortic aneurysm models (AAMs). Discretization of governing equations was achieved using a finite element scheme. Maximum turbulence-induced shear stress was found at the distal end of an AAM. In large AAMs (dilated to undilated diameter ratio = 3.33) at peak systolic flow velocity, fluid shear stress during exercise is 70.4% higher than at rest. Our study provides a numerical, noninvasive method for obtaining detailed data on the forces generated by pulsatile turbulent flow in AAAs that are difficult to study in humans and in physical models. Our data suggest that increased flow turbulence results in increased shear stress in aneurysms. While pressure readings are fairly uniform along the length of an aneurysm, the kinetic energy generated by turbulence impacting on the wall of the distal half of the aneurysm increases fluid and wall shear stress at this site. If the increased fluid shear stress results in further dilation and hence further turbulence, wall stress may be a mechanism for aneurysmal growth and eventual rupture.

Open-type miniature heat pipes

DOE Office of Scientific and Technical Information (OSTI.GOV)

Vasiliev, L.L.

1994-01-01

The hypothesis that systems of thermoregulation, similar to open-type micro heat pipes, exist in nature (soils, living organisms, plants) and in a number of technological processes (drying, thermodynamic cycles on solid adsorbents) is considered. The hydrodynamics and heat transfer in such thermoregulation systems differ from the hydrodynamics and heat transfer in classical heat pipes, since their geometrical dimensions are extremely small (dozens of microns), adhesion forces are powerful, the effect of the field of capillary and gravitational forces is significant, and strong interaction between counter-current flows of vapor and liquid takes place.

Electromotive force and large-scale magnetic dynamo in a turbulent flow with a mean shear.

PubMed

Rogachevskii, Igor; Kleeorin, Nathan

2003-09-01

An effect of sheared large-scale motions on a mean electromotive force in a nonrotating turbulent flow of a conducting fluid is studied. It is demonstrated that in a homogeneous divergence-free turbulent flow the alpha effect does not exist, however a mean magnetic field can be generated even in a nonrotating turbulence with an imposed mean velocity shear due to a "shear-current" effect. A mean velocity shear results in an anisotropy of turbulent magnetic diffusion. A contribution to the electromotive force related to the symmetric parts of the gradient tensor of the mean magnetic field (the kappa effect) is found in nonrotating turbulent flows with a mean shear. The kappa effect and turbulent magnetic diffusion reduce the growth rate of the mean magnetic field. It is shown that a mean magnetic field can be generated when the exponent of the energy spectrum of the background turbulence (without the mean velocity shear) is less than 2. The shear-current effect was studied using two different methods: the tau approximation (the Orszag third-order closure procedure) and the stochastic calculus (the path integral representation of the solution of the induction equation, Feynman-Kac formula, and Cameron-Martin-Girsanov theorem). Astrophysical applications of the obtained results are discussed.

Experimental study of the free surface velocity field in an asymmetrical confluence

NASA Astrophysics Data System (ADS)

Creelle, Stephan; Mignot, Emmanuel; Schindfessel, Laurent; De Mulder, Tom

2017-04-01

The hydrodynamic behavior of open channel confluences is highly complex because of the combination of different processes that interact with each other. To gain further insights in how the velocity uniformization between the upstream channels and the downstream channel is proceeding, experiments are performed in a large scale 90 degree angled concrete confluence flume with a chamfered rectangular cross-section and a width of 0.98m. The dimensions and lay-out of the flume are representative for a prototype scale confluence in e.g. drainage and irrigation systems. In this type of engineered channels with sharp corners the separation zone is very large and thus the velocity difference between the most contracted section and the separation zone is pronounced. With the help of surface particle tracking velocimetry the velocity field is recorded from upstream of the confluence to a significant distance downstream of the confluence. The resulting data allow to analyze the evolution of the incoming flows (with a developed velocity profile) that interact with the stagnation zone and each other, causing a shear layer between the two bulk flows. Close observation of the velocity field near the stagnation zone shows that there are actually two shear layers in the vicinity of the upstream corner. Furthermore, the data reveals that the shear layer observed more downstream between the two incoming flows is actually one of the two shear layers next to the stagnation zone that continues, while the other shear layer ceases to exist. The extensive measurement domain also allows to study the shear layer between the contracted section and the separation zone. The shear layers of the stagnation zone between the incoming flows and the one between the contracted flow and separation zone are localized and parameters such as the maximum gradient, velocity difference and width of the shear layer are calculated. Analysis of these data shows that the shear layer between the incoming flows disappears quite quickly, because of the severe flow contraction that aids the flow uniformization. This is also accelerated because of a flow redistribution process that starts already upstream of the confluence, resulting in a lower than expected velocity difference over the shear layer between the bulk of the incoming flows. In contrast, the shear layer between the contracted section and the separation zone proves to be of a significantly higher order of magnitude, with large turbulent structures appearing that get transported far downstream. In conclusion, the resulting understanding of this analysis of velocity fields with a larger field of view shows that when analyzing confluence hydrodynamics, one should pay ample attention to analyze data far enough up and downstream to assess all the relevant processes.

Shear wave mapping of skeletal muscle using shear wave wavefront reconstruction based on ultrasound color flow imaging

NASA Astrophysics Data System (ADS)

Yamakoshi, Yoshiki; Yamamoto, Atsushi; Kasahara, Toshihiro; Iijima, Tomohiro; Yuminaka, Yasushi

2015-07-01

We have proposed a quantitative shear wave imaging technique for continuous shear wave excitation. Shear wave wavefront is observed directly by color flow imaging using a general-purpose ultrasonic imaging system. In this study, the proposed method is applied to experiments in vivo, and shear wave maps, namely, the shear wave phase map, which shows the shear wave propagation inside the medium, and the shear wave velocity map, are observed for the skeletal muscle in the shoulder. To excite the shear wave inside the skeletal muscle of the shoulder, a hybrid ultrasonic wave transducer, which combines a small vibrator with an ultrasonic wave probe, is adopted. The shear wave velocity of supraspinatus muscle, which is measured by the proposed method, is 4.11 ± 0.06 m/s (N = 4). This value is consistent with those obtained by the acoustic radiation force impulse method.

An easy to assemble microfluidic perfusion device with a magnetic clamp

PubMed Central

Tkachenko, Eugene; Gutierrez, Edgar; Ginsberg, Mark H.; Groisman, Alex

2009-01-01

We have built and characterized a magnetic clamp for reversible sealing of PDMS microfluidic chips against cover glasses with cell cultures and a microfluidic chip for experiments on shear stress response of endothelial cells. The magnetic clamp exerts a reproducible uniform pressure on the microfluidic chip, achieving fast and reliable sealing for liquid pressures up to 40 kPa inside the chip with <10% deformations of microchannels and minimal variations of the substrate shear stress in perfusion flow. The microfluidic chip has 8 test regions with the substrate shear stress varying by a factor of 2 between each region, thus covering a 128-fold range from low venous to arterial. The perfusion is driven by differential pressure, which makes it possible to create pulsatile flows mimicking pulsing in the vasculature. The setup is tested by 15 – 40 hours perfusions over endothelial monolayers with shear stress in the range of 0.07 - 9 dyn/cm2. Excellent cell viability at all shear stresses and alignment of cells along the flow at high shear stresses are repeatedly observed. A scratch wound healing assay under a shear flow is demonstrated and cell migration velocities are measured. Transfection of cells with a fluorescent protein is performed, and migrating fluorescent cells are imaged at a high resolution under shear flow in real time. The magnetic clamp can be closed with minimal mechanical perturbation to cells on the substrate and used with a variety of microfluidic chips for experiments with adherent and non-adherent cells. PMID:19350090

PREPARATIVE ISOLATION AND PURIFICATION OF THREE GLYCINE-CONJUGATED CHOLIC ACIDS FROM PULVIS FELLIS SUIS BY HIGH-SPEED COUNTERCURRENT CHROMATOGRAPHY COUPLED WITH ELSD DETECTION.

PubMed

He, Jiao; Li, Jing; Sun, Wenji; Zhang, Tianyou; Ito, Yoichiro

2012-01-01

Coupled with evaporative light scattering detection, a high-speed counter-current chromatography (HSCCC) method was developed for preparative isolation and purification of three glycine-conjugated cholic acids, glycochenodeoxycholic acid (GCDCA), glycohyodeoxycholic acid (GHDCA) and glycohyocholic acid (GHCA) from Pulvis Fellis Suis (Pig gallbladder bile) for the first time. The separation was performed with a two-phase solvent system consisted of chloroform-methanol-water-acetic acid (65:30:10:1.5, v/v/v/v) by eluting the lower phase in the head-to-tail elution mode. The revolution speed of the separation column, flow rate of the mobile phase and separation temperature were 800 rpm, 2 ml/min and 25 °C, respectively. In a single operation, 33 mg of GCDCA, 38 mg of GHDCA and 23 mg of GHCA were obtained from 200 mg of crude extract with the purity of 95.65%, 96.72% and 96.63%, respectively, in one step separation. The HSCCC fractions were analyzed by high-performance liquid chromatography (HPLC) and the structures of the three glycine-conjugated cholic acids were identified by ESI-MS, (1)H NMR and (13)C NMR.

Investigation of nutrient feeding strategies in a countercurrent mixed-acid multi-staged fermentation: development of segregated-nitrogen model.

PubMed

Smith, Aaron D; Holtzapple, Mark T

2010-12-01

The MixAlco process is a biorefinery based on the production of carboxylic acids via mixed-culture fermentation. Nitrogen is essential for microbial growth and metabolism, and may exist in soluble (e.g., ammonia) or insoluble forms (e.g., cells). Understanding the dynamics of nitrogen flow in a countercurrent fermentation is necessary to develop control strategies to maximize performance. To estimate nitrogen concentration profiles in a four-stage fermentation train, a mass balance-based segregated-nitrogen model was developed, which uses separate balances for solid- and liquid-phase nitrogen with nitrogen reaction flux between phases assumed to be zero. Comparison of predictions with measured nitrogen profiles from five trains, each with a different nutrient contacting pattern, shows the segregated-nitrogen model captures basic behavior and is a reasonable tool for estimating nitrogen profiles. The segregated-nitrogen model may be used to (1) estimate optimal nitrogen loading patterns, (2) develop a reaction-based model, (3) understand influence of model inputs (e.g., operating parameters, feedstock properties, nutrient loading pattern) on the steady-state nitrogen profile, and (4) determine the direction of the nitrogen reaction flux between liquid and solid phases. Copyright (c) 2010 Elsevier Ltd. All rights reserved.

PREPARATIVE ISOLATION AND PURIFICATION OF THREE GLYCINE-CONJUGATED CHOLIC ACIDS FROM PULVIS FELLIS SUIS BY HIGH-SPEED COUNTERCURRENT CHROMATOGRAPHY COUPLED WITH ELSD DETECTION

PubMed Central

He, Jiao; Li, Jing; Sun, Wenji; Zhang, Tianyou; Ito, Yoichiro

2011-01-01

Coupled with evaporative light scattering detection, a high-speed counter-current chromatography (HSCCC) method was developed for preparative isolation and purification of three glycine-conjugated cholic acids, glycochenodeoxycholic acid (GCDCA), glycohyodeoxycholic acid (GHDCA) and glycohyocholic acid (GHCA) from Pulvis Fellis Suis (Pig gallbladder bile) for the first time. The separation was performed with a two-phase solvent system consisted of chloroform-methanol-water-acetic acid (65:30:10:1.5, v/v/v/v) by eluting the lower phase in the head-to-tail elution mode. The revolution speed of the separation column, flow rate of the mobile phase and separation temperature were 800 rpm, 2 ml/min and 25 °C, respectively. In a single operation, 33 mg of GCDCA, 38 mg of GHDCA and 23 mg of GHCA were obtained from 200 mg of crude extract with the purity of 95.65%, 96.72% and 96.63%, respectively, in one step separation. The HSCCC fractions were analyzed by high-performance liquid chromatography (HPLC) and the structures of the three glycine-conjugated cholic acids were identified by ESI-MS, 1H NMR and 13C NMR. PMID:23008527

Analytical separation of tea catechins and food-related polyphenols by high-speed counter-current chromatography.

PubMed

Yanagida, Akio; Shoji, Atsushi; Shibusawa, Yoichi; Shindo, Heisaburo; Tagashira, Motoyuki; Ikeda, Mitsuo; Ito, Yoichiro

2006-04-21

High-speed counter-current chromatography (HSCCC) using the type-J coil planet centrifuge was applied to compositional analysis of tea catechins and separation of other food-related polyphenols. The HSCCC separation of nine different standard compounds and those from extracts of commercial tea leaves was performed with a two-phase solvent system composed of tert-butyl methyl ether-acetonitrile-0.1% aqueous trifluoroacetic acid (TFA) (2:2:3, v/v/v) by eluting the upper organic phase at a flow rate of 2 ml/min. The main compounds in the extract of non-fermented green tea were found to be monomeric catechins, their galloylated esters and caffeine. In addition to these compounds, oxidized pigments, such as hydrophobic theaflavins (TFs) and polar thearubigins (TRs) were also separated and detected from the extracts of semi-fermented oolong tea and fermented black tea. Furthermore, several food-related polyphenols, such as condensed catechin oligomers (procyanidins), phenolic acids and flavonol glycosides were clearly separated under the same HSCCC condition. These separation profiles of HSCCC provide useful information about the hydrophobic diversity of these bioactive polyphenols present in various types of teas and food products.

Expulsion of swimming bacteria by a circular flow

NASA Astrophysics Data System (ADS)

Sokolov, Andrey; Aronson, Igor

Macroscopic shear flow alters swimming trajectories in a highly nontrivial way and results in dramatic reduction of viscosity and heterogeneous bacterial distributions. We report on experimental and theoretical studies of rapid expulsion of microswimmers, such as motile bacteria, by a circular flow created by a rotating microparticle. We observed a formation of a macroscopic depletion area in a high-shear region, in the vicinity of a microparticle. The rapid migration of bacteria from the shear-rich area is caused by a circular structure of the flow rather than intrinsic random fluctuations of bacteria orientations, in stark contrast to planar shear flow. Our mathematical model revealed that expulsion is a combined effect of motility and alignment by a vortical flow. Our findings offer a novel approach for manipulation of motile microorganisms and shed new light on bacteria-flow interactions. Was supported by the US DOE, Office of Basic Energy Sciences, Division of Materials Science And Engineering, under Contract No. DE AC02-06CH11357.

Flow induced protein nucleation: Insulin oligomerization under shear.

NASA Astrophysics Data System (ADS)

Dexter, Andrew; Azadani, Ali; Sorci, Mirco; Belfort, Georges; Hirsa, Amir

2007-11-01

A large number of diseases are associated with protein aggregation and misfolding, such as Alzheimer's, Parkinson's and human prion diseases such as Creutzveld-Jakob disease. Characteristic of these diseases is the presence of amyloid fibrils and their precursors, oligomers and protofibrils. Considerable evidence exists that a shearing flow strongly influences amyloid formation both in vitro and in vivo. Furthermore, the stability of protein-based pharmaceuticals is essential for conventional therapeutic preparations and drug delivery systems. By studying the nucleation and growth of insulin fibrils in a well-defined flow system, we expect to identify the flow conditions that impact protein aggregation kinetics and which lead to protein destabilization. The present flow system consists of an annular region bounded by stationary inner and outer cylinders and is driven by rotation of the floor. Preliminary results indicate that a continuous shearing flow can accelerate the aggregation process. The interfacial shear viscosity was found to drastically increase during aggregation and appears to be a useful parameter to probe protein oligomerization and the effects of flow.

Dual pressure-dual temperature isotope exchange process

DOEpatents

Babcock, D.F.

1974-02-12

A liquid and a gas stream, each containing a desired isotope, flow countercurrently through two liquid-gas contacting towers maintained at different temperatures and pressures. The liquid is enriched in the isotope in one tower while the gas is enriched within the other and a portion of at least one of the enriched streams is withdrawn from the system for use or further enrichment. The tower operated at the lower temperature is also maintained at the lower pressure to prevent formation of solid solvates. Gas flow between the towers passes through an expander-compressor apparatas to recover work from the expansion of gas to the lower pressure and thereby compress the gas returning to the tower of higher pressure. (Official Gazette)

Nonlinear evolution of the Kelvin-Helmholtz instability in the double current sheet configuration

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mao, Aohua; Li, Jiquan, E-mail: lijq@energy.kyoto-u.ac.jp; Kishimoto, Yasuaki

2016-03-15

The nonlinear evolution of the Kelvin-Helmholtz (KH) instability driven by a radially antisymmetric shear flow in the double current sheet configuration is numerically investigated based on a reduced magnetohydrodynamic model. Simulations reveal different nonlinear fate of the KH instability depending on the amplitude of the shear flow, which restricts the strength of the KH instability. For strong shear flows far above the KH instability threshold, the linear electrostatic-type KH instability saturates and achieves a vortex flow dominated quasi-steady state of the electromagnetic (EM) KH turbulence with large-amplitude zonal flows as well as zonal fields. The magnetic surfaces are twisted significantlymore » due to strong vortices but without the formation of magnetic islands. However, for the shear flow just over the KH instability threshold, a weak EM-type KH instability is saturated and remarkably damped by zonal flows through modifying the equilibrium shear flow. Interestingly, a secondary double tearing mode (DTM) is excited subsequently in highly damped KH turbulence, behaving as a pure DTM in a flowing plasma as described in Mao et al. [Phys. Plasmas 21, 052304 (2014)]. However, the explosive growth phenomenon is replaced by a gradually growing oscillation due to the extremely twisted islands. As a result, the release of the magnetic energy becomes slow and the global magnetic reconnection tends to be gentle. A complex nonlinear interaction between the EM KH turbulence and the DTMs occurs for the medium shear flows above the KH instability threshold, turbulent EM fluctuations experience oscillatory nonlinear growth of the DTMs, finally achieves a quasi-steady state with the interplay of the fluctuations between the DTMs and the EM KH instability.« less

Sudden Relaminarization and Lifetimes in Forced Isotropic Turbulence.

PubMed

Linkmann, Moritz F; Morozov, Alexander

2015-09-25

We demonstrate an unexpected connection between isotropic turbulence and wall-bounded shear flows. We perform direct numerical simulations of isotropic turbulence forced at large scales at moderate Reynolds numbers and observe sudden transitions from a chaotic dynamics to a spatially simple flow, analogous to the laminar state in wall bounded shear flows. We find that the survival probabilities of turbulence are exponential and the typical lifetimes increase superexponentially with the Reynolds number. Our results suggest that both isotropic turbulence and wall-bounded shear flows qualitatively share the same phase-space dynamics.

Study on shearing force and impact force of a volcanic mud flow on Mt. Sakurajima

Treesearch

Yoshinobu Taniguchi

1991-01-01

Two kinds of shearing stress meters (type A and type B) were set on the channel bottom in the Arimura River and the Mochiki River on Mt. Sakurajima. Volcanic mud flows take place there about 100 times a year. The results of the surveys demonstrated that the actual shearing force of a volcanic mud flow on Mt. Sakurajima was from 0.46 to 2.50 kgf/cm2...

Hybrid channel flow-type mechanisms in the Greater Himalayan Sequence (West Nepal): new constraints from vorticity of flow and quartz petrofabric analyses.

NASA Astrophysics Data System (ADS)

Frassi, Chiara

2016-04-01

Three main tectono-metamorphic units are classically recognized along the Himalayan belt: the Lesser Himalayan (LH), the Greater Himalayan sequence (GHS) and the Tibetan Sedimentary sequence (TSS). The GHS may be interpreted as a low-viscosity tabular body of mid-crustal rocks extruded southward in Miocene times beneath the Tibetan plateau between two parallel and opposite-sense crustal-scale shear zones: the Main Central thrust at the base, and the South Tibetan Detachment system at the top. The pre-/syn-shearing mineral assemblage documented within these crustal-scale shear zones indicates that the metamorphic grade increases toward the core of the GHS producing an inverted and a normal thermal gradient respectively on the top and on the bottom of the slab. In addition, thermal profiles estimated using both petrology- and microstructures/fabrics-based thermometers indicate that the metamorphic isograds are condensed. Although horizontal extension and vorticity estimates collected across the GHS could be strongly biased by the criteria used to define the map position of the MCT, published vorticity data document general shear flow (1>Wk>0) within the slab with a pure-shear component of flow slightly predominant within the core of the GHS whereas the simple-shear component seems to dominate at the top of the slab. The lower boundary of the GHS records a general shear flow with a comparable contribution of simple and pure shearing. The associated crustal extrusion is compatible with Couette - Poiseuille velocity flow profile as assumed in crustal-scale channel flow-type models In this study, the quartz c-axis petrofabrics, vorticity and deformation-temperature studies are integrated with microstructures and metamorphic studies to individuate the location of the MCT and to document the spatial distribution of ductile deformation patterns across the lower portion of the GHS exposed in the Chaudabise river valley in western Nepal. My results indicate that the Main Central Thrust is located ˜5 km structurally below the previous mapped locations. Deformation temperature increases up structural section from ˜450°C to ˜650°C and overlaps with peak metamorphic temperature indicating that penetrative shearing was responsible for the exhumation of the GHS occurred at "close" to peak metamorphic conditions. I interpreted the telescoping and the inversion of the paleo-isotherms at the base of the GHS as produced mainly by a sub-simple shearing (Wm = 0.88-1) pervasively distributed through the lower portion of the GHS. The results are consistent with hybrid channel flow-type models where the boundary between lower and upper portions of the GHS, broadly corresponding to the tectono-metamorphic discontinuity recently documented in west Nepal, represents the limit between buried material, affected by dominant simple shearing, and exhumed material affected by a general flow dominates by pure shearing. This interpretation is consistent with the recent models suggesting the simultaneous operation of channel flow- and critical wedge-type processes at different structural depth.

How-to-Do-It: Countercurrent Heat Exchange in Vertebrate Limbs.

ERIC Educational Resources Information Center

Franklin, George B.; Plakke, Ronald K.

1988-01-01

Describes principals of physics that are manifested in simple biological systems of heat conservation structures. Outlines materials needed, data collection, analysis, and discussion questions for construction and operation of two models, one that is a countercurrent heat exchange model and one that is not. (RT)

Counter-current carbon dioxide purification of partially deacylated sunflower oil

USDA-ARS?s Scientific Manuscript database

High oleic sunflower oil was partially deacylated by propanolysis to produce a mixture of diglycerides and triglycerides. To remove by-product fatty acid propyl esters (FAPEs) from this reaction mixture, a liquid carbon dioxide (L-CO2) counter-current fractionation method was developed. The fracti...

Mineral lineation produced by 3-D rotation of rigid inclusions in confined viscous simple shear

NASA Astrophysics Data System (ADS)

Marques, Fernando O.

2016-08-01

The solid-state flow of rocks commonly produces a parallel arrangement of elongate minerals with their longest axes coincident with the direction of flow-a mineral lineation. However, this does not conform to Jeffery's theory of the rotation of rigid ellipsoidal inclusions (REIs) in viscous simple shear, because rigid inclusions rotate continuously with applied shear. In 2-dimensional (2-D) flow, the REI's greatest axis (e1) is already in the shear direction; therefore, the problem is to find mechanisms that can prevent the rotation of the REI about one axis, the vorticity axis. In 3-D flow, the problem is to find a mechanism that can make e1 rotate towards the shear direction, and so generate a mineral lineation by rigid rotation about two axes. 3-D analogue and numerical modelling was used to test the effects of confinement on REI rotation and, for narrow channels (shear zone thickness over inclusion's least axis, Wr < 2), the results show that: (1) the rotational behaviour deviates greatly from Jeffery's model; (2) inclusions with aspect ratio Ar (greatest over least principle axis, e1/e3) > 1 can rotate backwards from an initial orientation w e1 parallel to the shear plane, in great contrast to Jeffery's model; (3) back rotation is limited because inclusions reach a stable equilibrium orientation; (4) most importantly and, in contrast to Jeffery's model and to the 2-D simulations, in 3-D, the confined REI gradually rotated about an axis orthogonal to the shear plane towards an orientation with e1 parallel to the shear direction, thus producing a lineation parallel to the shear direction. The modelling results lead to the conclusion that confined simple shear can be responsible for the mineral alignment (lineation) observed in ductile shear zones.

Effect of exercise on hemodynamic conditions in the abdominal aorta.

PubMed

Taylor, C A; Hughes, T J; Zarins, C K

1999-06-01

The beneficial effect of exercise in the retardation of the progression of cardiovascular disease is hypothesized to be caused, at least in part, by the elimination of adverse hemodynamic conditions, including flow recirculation and low wall shear stress. In vitro and in vivo investigations have provided qualitative and limited quantitative information on flow patterns in the abdominal aorta and on the effect of exercise on the elimination of adverse hemodynamic conditions. We used computational fluid mechanics methods to examine the effects of simulated exercise on hemodynamic conditions in an idealized model of the human abdominal aorta. A three-dimensional computer model of a healthy human abdominal aorta was created to simulate pulsatile aortic blood flow under conditions of rest and graded exercise. Flow velocity patterns and wall shear stress were computed in the lesion-prone infrarenal aorta, and the effects of exercise were determined. A recirculation zone was observed to form along the posterior wall of the aorta immediately distal to the renal vessels under resting conditions. Low time-averaged wall shear stress was present in this location, along the posterior wall opposite the superior mesenteric artery and along the anterior wall between the superior and inferior mesenteric arteries. Shear stress temporal oscillations, as measured with an oscillatory shear index, were elevated in these regions. Under simulated light exercise conditions, a region of low wall shear stress and high oscillatory shear index remained along the posterior wall immediately distal to the renal arteries. Under simulated moderate exercise conditions, all the regions of low wall shear stress and high oscillatory shear index were eliminated. This numeric investigation provided detailed quantitative data on the effect of exercise on hemodynamic conditions in the abdominal aorta. Our results indicated that moderate levels of lower limb exercise are necessary to eliminate the flow reversal and regions of low wall shear stress in the abdominal aorta that exist under resting conditions. The lack of flow reversal and increased wall shear stress during exercise suggest a mechanism by which exercise may promote arterial health, namely with the elimination of adverse hemodynamic conditions.

Elution-extrusion counter-current chromatography for the separation of two pairs of isomeric monoterpenes from Paeoniae Alba Radix.

PubMed

Chu, Chu; Zhang, Shidi; Tong, Shengqiang; Li, Xingnuo; Li, Qingyong; Yan, Jizhong

2015-09-01

In this work, a simple and efficient protocol for the rapid separation of two pairs of isomeric monoterpenes from Paeoniae Alba Radix was developed by combining macroporous resin and elution-extrusion counter-current chromatography. The crude extract was firstly subjected to a D101 macroporous resin column eluted with water and a series of different concentrations of ethanol. Then, effluents of 30 and 95% ethanol were collected as sample 1 and sample 2 for further counter-current chromatography purification. Finally, a pair of isomers, 96 mg of compound 1 and 48 mg of compound 2 with purities of 91.1 and 96.2%, respectively, was isolated from 200 mg of sample 1. The other pair of isomers, 14 mg of compound 3 and 8 mg of compound 4 with purities of 93.6 and 88.9%, respectively, was isolated from 48 mg of sample 2. Their purities were analyzed by high-performance liquid chromatography, and their chemical structures were identified by mass spectrometry and (1) H NMR spectroscopy. Compared to a normal counter-current chromatography separation, the separation time and solvent consumption of elution-extrusion counter-current chromatography were reduced while the resolutions were still good. The established protocol is promising for the separation of natural products with great disparity of content in herbal medicines. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Structural characteristics of cohesive flow deposits, and a sedimentological approach on their flow mechanisms.

NASA Astrophysics Data System (ADS)

Tripsanas, E. K.; Bryant, W. R.; Prior, D. B.

2003-04-01

A large number of Jumbo Piston cores (up to 20 m long), acquired from the continental slope and rise of the Northwest Gulf of Mexico (Bryant Canyon area and eastern Sigsbee Escarpment), have recovered various mass-transport deposits. The main cause of slope instabilities over these areas is oversteepening of the slopes due to the seaward mobilization of the underlying allochthonous salt masses. Cohesive flow deposits were the most common recoveries in the sediment cores. Four types of cohesive flow deposits have been recognized: a) fluid debris flow, b) mud flow, c) mud-matrix dominated debris flow, and d) clast-dominated debris flow deposits. The first type is characterized by its relatively small thickness (less than 1 m), a mud matrix with small (less than 0.5 cm) and soft mud-clasts, and a faint layering. The mud-clasts reveal a normal grading and become more abundant towards the base of each layer. That reveals that their deposition resulted by several successive surges/pulses, developed in the main flow, than the sudden “freezing” of the whole flow. The main difference between mud flow and mud-matrix dominated debris flow deposits is the presence of small to large mud-clasts in the later. Both deposits consist of a chaotic mud-matrix, and a basal shear laminated zone, where the strongest shearing of the flow was exhibited. Convolute laminations, fault-like surfaces, thrust faults, and microfaults are interpreted as occurring during the “freezing” of the flows and/or by adjustments of the rested deposits. Clast-dominated debris flow deposits consist of three zones: a) an upper plug-zone, characterized by large interlocked clasts, b) a mid-zone, of higher reworked, inversely graded clasts, floating in a mud-matrix, and c) a lower shear laminated zone. The structure of the last three cohesive flow deposits indicate that they represent deposition of typical Bingham flows, consisting of an upper plug-zone in which the yield stress is not exceeded and an underlain shearing zone, where the shear stress exceeded the yield strength of the sediments. Mud-matrix, and clast-dominated debris flow deposits are the pervasive ones. Intensely sheared thin layers (5- to 20 cm) with sharp bases, displayed as successive layers at the base of mud/debris flow deposits, or as isolated depositional units interbedded in hemipelagic sediments, are as interesting, as enigmatic. They are interpreted as basal self-lubricating layers, of having high shear stress and pore pressures, over which the mud/debris flows were able to travel for very long distances.

Superposition rheology.

PubMed

Dhont, J K; Wagner, N J

2001-02-01

The interpretation of superposition rheology data is still a matter of debate due to lack of understanding of viscoelastic superposition response on a microscopic level. So far, only phenomenological approaches have been described, which do not capture the shear induced microstructural deformation, which is responsible for the viscoelastic behavior to the superimposed flow. Experimentally there are indications that there is a fundamental difference between the viscoelastic response to an orthogonally and a parallel superimposed shear flow. We present theoretical predictions, based on microscopic considerations, for both orthogonal and parallel viscoelastic response functions for a colloidal system of attractive particles near their gas-liquid critical point. These predictions extend to values of the stationary shear rate where the system is nonlinearly perturbed, and are based on considerations on the colloidal particle level. The difference in response to orthogonal and parallel superimposed shear flow can be understood entirely in terms of microstructural distortion, where the anisotropy of the microstructure under shear flow conditions is essential. In accordance with experimental observations we find pronounced negative values for response functions in case of parallel superposition for an intermediate range of frequencies, provided that microstructure is nonlinearly perturbed by the stationary shear component. For the critical colloidal systems considered here, the Kramers-Kronig relations for the superimposed response functions are found to be valid. It is argued, however, that the Kramers-Kronig relations may be violated for systems where the stationary shear flow induces a considerable amount of new microstructure.

Shear-thickening behavior of Fe-ZSM5 zeolite slurry and its removal with alumina/boehmites

NASA Astrophysics Data System (ADS)

Liu, Xiao-guang; Li, Yan; Xue, Wen-dong; Sun, Jia-lin; Tang, Qian

2018-06-01

A cryogenic scanning electron microscopy (cryo-SEM) technique was used to explore the shear-thickening behavior of Fe-ZSM5 zeolite pastes and to discover its underlying mechanism. Bare Fe-ZSM5 zeolite samples were found to contain agglomerations, which may break the flow of the pastes and cause shear-thickening behaviors. However, the shear-thickening behaviors can be eliminated by the addition of halloysite and various boehmites because of improved particle packing. Furthermore, compared with pure Fe-ZSM5 zeolite samples and its composite samples with halloysite, the samples with boehmite (Pural SB or Disperal) additions exhibited network structures in their cryo-SEM images; these structures could facilitate the storage and release of flow water, smooth paste flow, and avoid shear-thickening. By contrast, another boehmite (Versal 250) formed agglomerations rather than network structures after being added to the Fe-ZSM5 zeolite paste and resulted in shear-thickening behavior. Consequently, the results suggest that these network structures play key roles in eliminating the shear-thickening behavior.

Recent Advances in Velocity Shear Driven Processes

NASA Astrophysics Data System (ADS)

Ganguli, G.

1996-11-01

Macroscopic flows are commonly encountered in a wide variety of plasmas and it is becoming increasingly apparent that the presence of shear in such flows can have a pronounced effect on the nonlinear evolution. For instance, in tokamak devices, sheared poloidal flows are thought to play a crucial role in the L--H transition. In laser-produced plasmas, strongly sheared plasma jets are believed to lead to the onset of intense lower-hybrid waves. In the natural plasma environment of the Earth's ionosphere and magnetosphere, observations indicate a correlation between inhomogeneous flows, plasma wave activity, and particle energization. Different physical processes in which shear-driven phenomenon may dominate span a wide range of spatiotemporal scales. Cross-scale coupling between them can play a vital role in determining the ultimate state of a plasma system which, for space plasmas, is an important factor responsible for the definition of ``space weather.'' Hence, the origin of sheared flows and the plasma response to them is a topic of considerable interest. Ongoing studies indicate that the influence of velocity shear can be generally classified into two broad categories, dissipative and reactive. In the dissipative category, low levels of shear can affect wave-particle interactions through resonance detuning which can substantially modify the normal modes and dispersive properties of a homogeneous plasma. A transverse velocity shear reduces the growth rates of the modes with frequencies lower than the ion-cyclotron frequency while it enhances those modes with frequencies around the ion-cyclotron frequency or larger. Sufficiently strong shear can induce a new class of oscillations via a reactive mechanism by creating neighboring regions with wave energy density of opposite sign. In general, depending on the magnitude and scale length, velocity shear can give rise to plasma oscillations in a very broad frequency and wavelength range. These properties and their applications to space and laboratory plasmas will be discussed.

Edge-Induced Shear Banding in Entangled Polymeric Fluids

NASA Astrophysics Data System (ADS)

Hemingway, Ewan J.; Fielding, Suzanne M.

2018-03-01

Despite decades of research, the question of whether solutions and melts of highly entangled polymers exhibit shear banding as their steady state response to a steadily imposed shear flow remains controversial. From a theoretical viewpoint, an important unanswered question is whether the underlying constitutive curve of shear stress σ as a function of shear rate γ ˙ (for states of homogeneous shear) is monotonic, or has a region of negative slope, d σ /d γ ˙ <0 , which would trigger banding. Attempts to settle the question experimentally via velocimetry of the flow field inside the fluid are often confounded by an instability of the free surface where the sample meets the outside air, known as "edge fracture." Here we show by numerical simulation that in fact even only very modest edge disturbances—which are the precursor of full edge fracture but might well, in themselves, go unnoticed experimentally—can cause strong secondary flows in the form of shear bands that invade deep into the fluid bulk. Crucially, this is true even when the underlying constitutive curve is monotonically increasing, precluding true bulk shear banding in the absence of edge effects.

Transition of basaltic lava from pahoehoe to aa, Kilauea Volcano, Hawaii: Field observations and key factors

USGS Publications Warehouse

Peterson, Donald W.; Tilling, Robert I.

1980-01-01

Nearly all Hawaiian basaltic lava erupts as pahoehoe, and some changes to aa during flowage and cooling; factors governing the transition involve certain critical relations between viscosity and rate of shear strain. If the lava slows, cools, and stops in direct response to concomitant increase in viscosity before these critical relations are reached, it remains pahoehoe. But, if flow mechanics (flow rate, flow dimensions, slope, momentum, etc.) impel the lava to continue to move and deform even after it has become highly viscous, the critical relations may be reached and the lava changes to aa.Typical modes of transition from pahoehoe to aa include: (1) spontaneous formation of relatively stiff clots in parts of the flowing lava where shear rate is highest; these clots grow into discrete, rough, sticky masses to which the remaining fluid lava incrementally adheres; (2) fragmentation and immersion of solid or semi-solid surface crusts of pahoehoe by roiling movements of the flow, forming cores of discrete, tacky masses; (3) sudden renewed movement of lava stored and cooled within surface reservoirs to form clots. The masses, fragments, and clots in these transition modes are characterized by spinose, granulated surfaces; as flow movement continues, the masses and fragments aggregate, fracture, and grind together, completing the transition to aa.Observations show that the critical relation between viscosity and rate of shear strain is inverse: if viscosity is low, a high rate of shear is required to begin the transition to aa; conversely, if viscosity is high, a much lower rate of shear will induce the transition. These relations can be demonstrated qualitatively with simple graphs, which can be used to examine the flow history of any selected finite lava element by tracing the path represented by its changing viscosity and shear rate. A broad, diffuse “transition threshold zone” in these graphs portrays the inverse critical relation between viscosity and shear rate; the transition to aa is represented by the path of the lava element crossing this zone.Moving lava flows can be regarded as natural viscometers, by which shear stress and rate of shear strain at selected points can be determined and viscosity can be computed. By making such determinations under a wide range of conditions on pahoehoe, aa, and transitional flow types, the critical relations that control the pahoehoe-aa transition can be quantified.

Oxygen and carbon dioxide transport in time-dependent blood flow past fiber rectangular arrays

NASA Astrophysics Data System (ADS)

Zierenberg, Jennifer R.; Fujioka, Hideki; Hirschl, Ronald B.; Bartlett, Robert H.; Grotberg, James B.

2009-03-01

The influence of time-dependent flows on oxygen and carbon dioxide transport for blood flow past fiber arrays arranged in in-line and staggered configurations was computationally investigated as a model for an artificial lung. Both a pulsatile flow, which mimics the flow leaving the right heart and passing through a compliance chamber before entering the artificial lung, and a right ventricular flow, which mimics flow leaving the right heart and directly entering the artificial lung, were considered in addition to a steady flow. The pulsatile flow was modeled as a sinusoidal perturbation superimposed on a steady flow while the right ventricular flow was modeled to accurately depict the period of flow acceleration (increasing flow) and deceleration (decreasing flow) during systole followed by zero flow during diastole. It was observed that the pulsatile flow yielded similar gas transport as compared to the steady flow, while the right ventricular flow resulted in smaller gas transport, with the decrease increasing with Re. The pressure drop across the fiber array (a measure of the resistance), work (an indicator of the work required of the right heart), and shear stress (a measure of potential blood cell activation and damage) are lowest for steady flow, followed by pulsatile flow, and then right ventricular flow. The pressure drop, work, shear stress, and Sherwood numbers (a measure of the gas transport efficiency) decrease with increasing porosity and are smaller for AR <1 as compared to AR >1 (AR is the distance between fibers in the flow direction/distance between fibers in direction perpendicular to flow), although for small porosities the Sherwood numbers are of similar magnitude. In general, for any fiber array geometry, high pressure drop, work, and shear stresses correlate with high Sherwood numbers, and low pressure drop, work, and shear stresses correlate with low Sherwood numbers creating a need for a compromise between pressure drop/work/shear stresses and gas transport.

Observation of the L-H confinement bifurcation triggered by a turbulence-driven shear flow in a tokamak plasma.

PubMed

Yan, Z; McKee, G R; Fonck, R; Gohil, P; Groebner, R J; Osborne, T H

2014-03-28

Comprehensive 2D turbulence and eddy flow velocity measurements on DIII-D demonstrate a rapidly increasing turbulence-driven shear flow that develops ∼100  μs prior to the low-confinement (L mode) to high-confinement (H mode) transition and appears to trigger it. These changes are localized to a narrow layer 1-2 cm inside the magnetic boundary. Increasing heating power increases the Reynolds stress, the energy transfer from turbulence to the poloidal flow, and the edge flow shearing rate that then exceeds the decorrelation rate, suppressing turbulence and triggering the transition.

Interaction of two cylinders in shear flow at low Wi

NASA Astrophysics Data System (ADS)

Brown, M. J.; Leal, L. G.

2001-11-01

Experiments [Lyon et al., 2001; Boussima et al., 1996; Michelle et al., 1977] have shown that non-Brownian, non-Colloidal, and charge-neutral particles, when suspended in viscoelastic media and subjected to shear, will aggregate and flow-align above a critical shear rate Wi O(10). Giesekus [1978] proposed a mechanism for aggregation based on the attractive hoop thrusts about two particles in viscoelastic flow. This pairwise mechanism of attraction is borne out in studies of sedimenting particles [Feng & Joseph, 1996; Joseph et al., 1994], and seems a valid explanation for the aggregation observed in sedimenting suspensions over all Wi > Re [Joseph et al., 1994; Phillips, 1996.] Consideration of the flow around two particles in shear would lead one to expect attraction by this hoop thrust mechanism as well. However, it remains unclear why shear-induced aggregation only occurs above a critical Wi. A first step in understanding this criticality is to establish the low Wi behavior of two particles in shear. In this talk, we report on the interaction of two freely-mobile cylinders as predicted by an n-th order fluid computation.

Asymmetric Reconnection With A Shear Flow and Applications to X-line Motion at the Polar Cusps

NASA Astrophysics Data System (ADS)

Doss, C.; Komar, C. M.; Beidler, M.; Cassak, P.; Wilder, F. D.; Eriksson, S.

2014-12-01

Magnetic reconnection at the polar cusps of the magnetosphere is marked by strong asymmetries in plasma density and magnetic field strength in addition to a potentially strong bulk flow shear parallel to the reconnecting magnetic field caused by the solar wind. Much has been learned about the effect of either asymmetries or shear flow on reconnection, but only a handful of studies have addressed systems with both. We perform a careful theoretical, numerical, and observational study of such systems. It is known that an asymmetry in magnetic field offsets the X-line from the center of the diffusion region in the inflow direction toward the weaker magnetic field. A key finding is that this alters the flow profile seen at the X-line relative to expectations from symmetric reconnection results. This causes the X-line to drift in the outflow direction due to the shear flow. We calculate a prediction for the X-line drift speed for arbitrary asymmetric magnetic field strengths and show the result is consistent with two-fluid numerical simulations. These predictions are also shown to be consistent with recent observations of a tailward moving X-line in Cluster observations of reconnection at the polar cusp. The reconnection rate with a shear flow is observed to drop as in symmetric reconnection, and the behavior of the reconnection qualitatively changes when the shear flow speed exceeds the hybrid Alfven speed of the outflow known from asymmetric reconnection theory.

Nonlinear oscillatory rheology and structure of wormlike micellar solutions and colloidal suspensions

NASA Astrophysics Data System (ADS)

Gurnon, Amanda Kate

The complex, nonlinear flow behavior of soft materials transcends industrial applications, smart material design and non-equilibrium thermodynamics. A long-standing, fundamental challenge in soft-matter science is establishing a quantitative connection between the deformation field, local microstructure and macroscopic dynamic flow properties i.e., the rheology. Soft materials are widely used in consumer products and industrial processes including energy recovery, surfactants for personal healthcare (e.g. soap and shampoo), coatings, plastics, drug delivery, medical devices and therapeutics. Oftentimes, these materials are processed by, used during, or exposed to non-equilibrium conditions for which the transient response of the complex fluid is critical. As such, designing new dynamic experiments is imperative to testing these materials and further developing micromechanical models to predict their transient response. Two of the most common classes of these soft materials stand as the focus of the present research; they are: solutions of polymer-like micelles (PLM or also known as wormlike micelles, WLM) and concentrated colloidal suspensions. In addition to their varied applications these two different classes of soft materials are also governed by different physics. In contrast, to the shear thinning behavior of the WLMs at high shear rates, the near hard-sphere colloidal suspensions are known to display increases, sometimes quite substantial, in viscosity (known as shear thickening). The stress response of these complex fluids derive from the shear-induced microstructure, thus measurements of the microstructure under flow are critical for understanding the mechanisms underlying the complex, nonlinear rheology of these complex fluids. A popular micromechanical model is reframed from its original derivation for predicting steady shear rheology of polymers and WLMs to be applicable to weakly nonlinear oscillatory shear flow. The validity, utility and limits of this constitutive model are tested by comparison with experiments on model WLM solutions. Further comparisons to the nonlinear oscillatory shear responses measured from colloidal suspensions establishes this analysis as a promising, quantitative method for understanding the underlying mechanisms responsible for the nonlinear dynamic response of complex fluids. A new experimental technique is developed to measure the microstructure of complex fluids during steady and transient shear flow using small-angle neutron scattering (SANS). The Flow-SANS experimental method is now available to the broader user communities at the NIST Center for Neutron Research, Gaithersburg, MD and the Institut Laue-Langevin, Grenoble, France. Using this new method, a model shear banding WLM solution is interrogated under steady and oscillatory shear. For the first time, the flow-SANS methods identify new metastable states for shear banding WLM solutions, thus establishing the method as capable of probing new states not accessible using traditional steady or linear oscillatory shear methods. The flow-induced three-dimensional microstructure of a colloidal suspension under steady and dynamic oscillatory shear is also measured using these rheo- and flow-SANS methods. A new structure state is identified in the shear thickening regime that proves critical for defining the "hydrocluster" microstructure state of the suspension that is responsible for shear thickening. For both the suspensions and the WLM solutions, stress-SANS rules with the measured microstructures define the individual stress components arising separately from conservative and hydrodynamic forces and these are compared with the macroscopic rheology. Analysis of these results defines the crucial length- and time-scales of the transient microstructure response. The novel dynamic microstructural measurements presented in this dissertation provide new insights into the complexities of shear thickening and shear banding flow phenomena, which are effects observed more broadly across many different types of soft materials. Consequently, the microstructure-rheology property relationships developed for these two classes of complex fluids will aid in the testing and advancement of micromechanical constitutive model development, smart material design, industrial processing and fundamental non-equilibrium thermodynamic research of a broad range of soft materials.

Shear-induced partial translational ordering of a colloidal solid

NASA Astrophysics Data System (ADS)

Ackerson, B. J.; Clark, N. A.

1984-08-01

Highly charged submicrometer plastic spheres suspended in water at low ionic strength will order spontaneously into bcc crystals or polycrystals. A simple linear shear orients and disorders these crystals by forcing (110) planes to stack normal to the shear gradient and to slide relative to each other with a <111> direction parallel to the solvent flow. In this paper we analyze in detail the disordering and flow processes occurring beyond the intrinsic elastic limit of the bcc crystal. We are led to a model in which the flow of a colloidal crystal is interpreted as a fundamentally different process from that found in atomic crystals. In the colloidal crystal the coupling of particle motion to the background fluid forces a homogeneous flow, where every layer is in motion relative to its neighboring layers. In contrast, the plastic flow in an atomic solid is defect mediated flow. At the lowest applied stress, the local bcc order in the colloidal crystal exhibits shear strains both parallel and perpendicular to the direction of the applied stress. The magnitude of these deformations is estimated using the configurational energy for bcc and distorted bcc crystals, assuming a screened Coulomb pair interaction between colloidal particles. As the applied stress is increased, the intrinsic elastic limit of the crystal is exceeded and the crystal begins to flow with adjacent layers executing an oscillatory path governed by the balance of viscous and screened Coulomb forces. The path takes the structure from the bcc1 and bcc2 twins observed at zero shear to a distorted two-dimensional hcp structure at moderate shear rates, with a loss of interlayer registration as the shear is increased. This theoretical model is consistent with other experimental observations, as well.

Bed Surface Adjustments to Spatially Variable Flow in Low Relative Submergence Regimes

NASA Astrophysics Data System (ADS)

Monsalve, A.; Yager, E. M.

2017-11-01

In mountainous rivers, large relatively immobile grains partly control the local and reach-averaged flow hydraulics and sediment fluxes. When the flow depth is similar to the size of these grains (low relative submergence), heterogeneous flow structures and plunging flow cause spatial distributions of bed surface elevations, textures, and sedimentation rates. To explore how the bed surface responds to these flow variations we conducted a set of experiments in which we varied the relative submergence of staggered hemispheres (simulated large boulders) between runs. All experiments had the same average sediment transport capacity, upstream sediment supply, and initial bed thickness and grain size distribution. We combined our laboratory measurements with a 3-D flow model to obtain the detailed flow structure around the hemispheres. The local bed shear stress field displayed substantial variability and controlled the bed load transport rates and direction in which sediment moved. The divergence in bed shear stress caused by the hemispheres promoted size-selective bed load deposition, which formed patches of coarse sediment upstream of the hemisphere. Sediment deposition caused a decrease in local bed shear stress, which combined with the coarser grain size, enhanced the stability of this patch. The region downstream of the hemispheres was largely controlled by a recirculation zone and had little to no change in grain size, bed elevation, and bed shear stress. The formation, development, and stability of sediment patches in mountain streams is controlled by the bed shear stress divergence and magnitude and direction of the local bed shear stress field.

Use DNA solutions to model polymer entanglement in flow: simultaneous rheometric and particle-tracking velocimetric measurements

NASA Astrophysics Data System (ADS)

Boukany, Pouyan; Wang, Shi-Qing

2008-03-01

Entangled aqueous DNA solutions are ideal as a model system to examine nonlinear flow features including stress overshoot in startup shear and shear thinning phenomenon. These soft systems can be strongly entangled with 60 entanglement points per chain and a terminal relaxation time as long as 1000 s at 1 % concentration [1-2]. They allow a comparison between the steady state attained with a startup shear and that attained through an ``infinitely'' slow ramping up of the applied shear rate. Indeed, startup shear in the nonlinear (stress plateau) region causes the DNA solutions to yield inhomogeneously, resulting in permanent shear banding. However, the slowly ramped-up shear into the same final rate as applied in startup shear allowed the solutions to avoid shear inhomogeneity. Thus, we demonstrated that it is possible for the final steady states to be different depending on how an entangled system is brought into the same final experimental condition. This result implies that it is ill-defined to pursue conventional constitutive relationship in flow of entangled polymers. [1] Boukany, P. E.; Hu, T. H.; Wang, S. Q. textitMacromolecules 2007, under review. [2] Boukany, P. E.; Wang, S. Q. J. Rheol. 2007, under review.

Wall shear measurement in sand-water mixture flows

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yucel, O.; Grad, W.H.

1975-07-01

The wall shear stress was measured in clear-water and sand-water mixture flows with the use of a flush-mounting hot-film shear-sensor. Data were obtained with 2 shear-sensors and 2 different sands (d50 = 0.45 mm and d50 = 0.88 mm) with solids concentrations of up to Cmax = 1.6% by vol, and for flow Reynolds number of 10/sup 5/ < RD < 6 x 10/sup 5/. The measured sensor wall shear stresses were compared with the true wall shear stresses obtained with the energy head loss measurements conducted in a pipeline system. The results of the tests in the clear-water flowsmore » confirmed the relationship between the sensor power output, Ps, and the wall shear stress, tauo, given by tauo1/3 = APs + B, in which A and B are calibration coefficients. The tests with the low-concentration sand-water mixtures in a vertical pipe indicated that for the present range of experiments, sensor power outputs with the mixtures exceeded those for clear-water by an average of 5%. It is shown that the shear sensors are delicate but accurate instruments that can be used for the measurement of the wall shear stress. (13 refs.)« less

Correlation between Reynolds number and eccentricity effect in stenosed artery models.

PubMed

Javadzadegan, Ashkan; Shimizu, Yasutomo; Behnia, Masud; Ohta, Makoto

2013-01-01

Flow recirculation and shear strain are physiological processes within coronary arteries which are associated with pathogenic biological pathways. Distinct Quite apart from coronary stenosis severity, lesion eccentricity can cause flow recirculation and affect shear strain levels within human coronary arteries. The aim of this study is to analyse the effect of lesion eccentricity on the transient flow behaviour in a model of a coronary artery and also to investigate the correlation between Reynolds number (Re) and the eccentricity effect on flow behaviour. A transient particle image velocimetry (PIV) experiment was implemented in two silicone based models with 70% diameter stenosis, one with eccentric stenosis and one with concentric stenosis. At different times throughout the flow cycle, the eccentric model was always associated with a greater recirculation zone length, maximum shear strain rate and maximum axial velocity; however, the highest and lowest impacts of eccentricity were on the recirculation zone length and maximum shear strain rate, respectively. Analysis of the results revealed a negative correlation between the Reynolds number (Re) and the eccentricity effect on maximum axial velocity, maximum shear strain rate and recirculation zone length. As Re number increases the eccentricity effect on the flow behavior becomes negligible.

An Experimental Investigation of an Airfoil Traversing Across a Shear Flow

NASA Astrophysics Data System (ADS)

Hamedani, Borhan A.; Naguib, Ahmed; Koochesfahani, Manoochehr

2017-11-01

While the aerodynamics of an airfoil in a uniform approach flow is well understood, less attention has been paid to airfoils in non-uniform flows. An aircraft encounters such flow, for example, during landing through the air wake of an aircraft carrier. The present work is focused on investigating the fundamental aerodynamics of airfoils in such an environment using canonical flow experiments. To generate a shear approach flow, a shaped honeycomb block is employed in a wind tunnel setup. Direct force measurements are performed on a NACA 0012 airfoil, with an aspect ratio of 1.8, as the airfoil traverses steadily across the shear region. Measurements are conducted at a chord Reynolds number Rec 75k, based on the mean approach stream velocity at the center of the shear zone, for a range of airfoil traverse velocities and angles of attack (0 - 12 degree). The results are compared to those obtained for the same airfoil when placed statically at different points along the traverse path inside the shear zone. The comparison enables examination of the applicability of quasi-steady analysis in computing the forces on the moving airfoil. This work is supported by ONR Grant Number N00014-16-1-2760.

Laser induced fluorescence measurements of ion velocity and temperature of drift turbulence driven sheared plasma flow in a linear helicon plasma device

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chakraborty Thakur, S.; Fedorczak, N.; Manz, P.

2012-08-15

Using laser induced fluorescence (LIF), radial profiles of azimuthal ion fluid velocity and ion temperature are measured in the controlled shear de-correlation experiment (CSDX) linear helicon plasma device. Ion velocities and temperatures are derived from the measured Doppler broadened velocity distribution functions of argon ions. The LIF system employs a portable, high power (>300 mW), narrowband ({approx}1 MHz) tunable diode laser-based system operating at 668.614 nm. Previous studies in CSDX have shown the existence of a radially sheared azimuthal flow as measured with time delay estimation methods and Mach probes. Here, we report the first LIF measurements of sheared plasmamore » fluid flow in CSDX. Above a critical magnetic field, the ion fluid flow profile evolves from radially uniform to peaked on axis with a distinct reversed flow region at the boundary, indicating the development of a sheared azimuthal flow. Simultaneously, the ion temperature also evolves from a radially uniform profile to a profile with a gradient. Measurements in turbulent and coherent drift wave mode dominated plasmas are compared.« less

MOBI: Microgravity Observations of Bubble Interactions

NASA Technical Reports Server (NTRS)

Koch, Donald L.; Sangani, Ashok

2004-01-01

One of the greatest uncertainties affecting the design of multiphase flow technologies for space exploration is the spatial distribution of phases that will arise in microgravity or reduced gravity. On Earth, buoyancy-driven motion predominates whereas the shearing of the bubble suspension controls its behavior in microgravity. We are conducting a series of ground-based experiments and a flight experiment spanning the full range of ratios of buoyancy to shear. These include: (1) bubbles rising in a quiescent liquid in a vertical channel; (2) weak shear flow induced by slightly inclining the channel; (3) moderate shear flow in a terrestrial vertical pipe flow; and (4) shearing of a bubble suspension in a cylindrical Couette cell in microgravity. We consider nearly monodisperse suspensions of 1 to 1.8 mm diameter bubbles in aqueous electrolyte solutions. The liquid velocity disturbance produced by bubbles in this size range can often be described using an inviscid analysis. Electrolytic solutions lead to hydrophilic repulsion forces that stabilize the bubble suspension without causing Marangoni stresses. We will discuss the mechanisms that control the flow behavior and phase distribution in the ground-based experiments and speculate on the factors that may influence the suspension flow and bubble volume fraction distribution in the flight experiment.

Flow Shears at the Poleward Boundary of Omega Bands Observed During Conjunctions of Swarm and THEMIS ASI

NASA Astrophysics Data System (ADS)

Liu, Jiang; Lyons, L. R.; Archer, W. E.; Gallardo-Lacourt, B.; Nishimura, Y.; Zou, Ying; Gabrielse, C.; Weygand, J. M.

2018-02-01

Omega bands are curved aurora forms that evolve from a quiet arc located along the poleward edge of a diffuse auroral band within the midnight to morningside auroral oval. They usually propagate eastward. Because omega bands are a significant contributor to an active magnetotail, knowledge about their generation is important for understanding tail dynamics. Previous studies have shown that auroral streamers, footprints of fast flows in the tail, can propagate into omega bands. Such events, however, are limited, and it is still unclear whether and how the flows trigger the bands. The ionospheric flows associated with omega bands may provide valuable information on the driving mechanisms of the bands. We examine these flows taking advantage of the conjunctions between the Swarm spacecraft and Time History of Events and Macroscale Interactions during Substorms all-sky imagers, which allow us to demonstrate the relative location of the flows to the omega bands' bright arcs for the first time. We find that a strong eastward ionospheric flow is consistently present immediately poleward of the omega band's bright arc, resulting in a sharp flow shear near the poleward boundary of the band. This ionospheric flow shear should correspond to a flow shear near the inner edge of the plasma sheet. This plasma sheet shear may drive a Kelvin-Helmholz instability which then distorts the quiet arc to form omega bands. It seems plausible that the strong eastward flows are driven by streamer-related fast flows or enhanced convection in the magnetotail.

Shear-layer structures in near-wall turbulence

NASA Technical Reports Server (NTRS)

Johansson, A. V.; Alfredsson, P. H.; Kim, J.

1987-01-01

The structure of internal shear layer observed in the near-wall region of turbulent flows is investigated by analyzing flow fields obtained from numerical simulations of channel and boundary-layer flows. It is found that the shear layer is an important contributor to the turbulence production. The conditionally averaged production at the center of the structure was almost twice as large as the long-time mean value. The shear-layer structure is also found to retain its coherence over streamwise distances on the order of a thousand viscous length units, and propagates with a constant velocity of about 10.6 u sub rho throughout the near wall region.

Blood Flow Modulation of Vascular Dynamics

PubMed Central

Lee, Juhyun; Sevag Packard, René R.; Hsiai, Tzung K.

2015-01-01

Purpose of review Blood flow is intimately linked with cardiovascular development, repair, and dysfunction. The current review will build on the fluid mechanical principle underlying hemodynamic shear forces, mechanotransduction, and metabolic effects. Recent findings Pulsatile flow produces both time- (∂τ /∂t)and spatial-varying shear stress (∂τ /∂x) to modulate vascular oxidative stress and inflammatory response with pathophysiological significance to atherosclerosis. The characteristics of hemodynamic shear forces; namely, steady laminar (∂τ /∂t= 0), pulsatile (PSS: unidirectional forward flow), and oscillatory shear stress (OSS: bidirectional with a near net 0 forward flow) modulate mechano-signal transduction to influence metabolic effects on vascular endothelial function. Atheroprotective PSS promotes anti-oxidant, anti-inflammatory, and anti-thrombotic responses, whereas atherogenic OSS induces NADPH oxidase–JNK signaling to increase mitochondrial superoxide production, protein degradation of manganese superoxide dismutase (MnSOD), and post-translational protein modifications of LDL particles in the disturbed flow-exposed regions of vasculature. In the era of tissue regeneration, shear stress has been implicated in re-activation of developmental genes; namely, Wnt and Notch signaling, for vascular development and repair. Summary Blood flow imparts a dynamic continuum from vascular development to repair. Augmentation of PSS confers atheroprotection and re-activation of developmental signaling pathways for regeneration. PMID:26218416

Transient Droplet Behavior and Droplet Breakup during Bulk and Confined Shear Flow in Blends with One Viscoelastic Component: Experiments, Modelling and Simulations

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cardinaels, Ruth; Verhulst, Kristof; Moldenaers, Paula

2008-07-07

The transient droplet deformation and droplet orientation after inception of shear, the shape relaxation after cessation of shear and droplet breakup during shear, are microscopically studied, both under bulk and confined conditions. The studied blends contain one viscoelastic Boger fluid phase. A counter rotating setup, based on a Paar Physica MCR300, is used for the droplet visualisation. For bulk shear flow, it is shown that the droplet deformation during startup of shear flow and the shape relaxation after cessation of shear flow are hardly influenced by droplet viscoelasticity, even at moderate to high capillary and Deborah numbers. The effects ofmore » droplet viscoelasticity only become visible close to the critical conditions and a novel break-up mechanism is observed. Matrix viscoelasticity has a more pronounced effect, causing overshoots in the deformation and significantly inhibiting relaxation. However, different applied capillary numbers prior to cessation of shear flow, with the Deborah number fixed, still result in a single master curve for shape retraction, as in fully Newtonian systems. The long tail in the droplet relaxation can be qualitatively described with a phenomenological model for droplet deformation, when using a 5-mode Giesekus model for the fluid rheology. It is found that the shear flow history significantly affects the droplet shape evolution and the breakup process in blends with one viscoelastic component. Confining a droplet between two plates accelerates the droplet deformation kinetics, similar to fully Newtonian systems. However, the increased droplet deformation, due to wall effects, causes the steady state to be reached at a later instant in time. Droplet relaxation is less sensitive to confinement, leading to slower relaxation kinetics only for highly confined droplets. For the blend with a viscoelastic droplet, a non-monotonous trend is found for the critical capillary number as a function of the confinement ratio. Finally, experimental data are compared with 3D simulations, performed with a volume-of-fluid algorithm.« less

In-situ temperature-controllable shear flow device for neutron scattering measurement--an example of aligned bicellar mixtures.

PubMed

Xia, Yan; Li, Ming; Kučerka, Norbert; Li, Shutao; Nieh, Mu-Ping

2015-02-01

We have designed and constructed a temperature-controllable shear flow cell for in-situ study on flow alignable systems. The device has been tested in the neutron diffraction and has the potential to be applied in the small angle neutron scattering configuration to characterize the nanostructures of the materials under flow. The required sample amount is as small as 1 ml. The shear rate on the sample is controlled by the flow rate produced by an external pump and can potentially vary from 0.11 to 3.8 × 10(5) s(-1). Both unidirectional and oscillational flows are achievable by the setting of the pump. The instrument is validated by using a lipid bicellar mixture, which yields non-alignable nanodisc-like bicelles at low T and shear-alignable membranes at high T. Using the shear cell, the bicellar membranes can be aligned at 31 °C under the flow with a shear rate of 11.11 s(-1). Multiple high-order Bragg peaks are observed and the full width at half maximum of the "rocking curve" around the Bragg's condition is found to be 3.5°-4.1°. It is noteworthy that a portion of the membranes remains aligned even after the flow stops. Detailed and comprehensive intensity correction for the rocking curve has been derived based on the finite rectangular sample geometry and the absorption of the neutrons as a function of sample angle [See supplementary material at http://dx.doi.org/10.1063/1.4908165 for the detailed derivation of the absorption correction]. The device offers a new capability to study the conformational or orientational anisotropy of the solvated macromolecules or aggregates induced by the hydrodynamic interaction in a flow field.

Shear stress increases nitric oxide production in thick ascending limbs

PubMed Central

Cabral, Pablo D.; Hong, Nancy J.

2010-01-01

We showed that luminal flow stimulates nitric oxide (NO) production in thick ascending limbs. Ion delivery, stretch, pressure, and shear stress all increase when flow is enhanced. We hypothesized that shear stress stimulates NO in thick ascending limbs, whereas stretch, pressure, and ion delivery do not. We measured NO in isolated, perfused rat thick ascending limbs using the NO-sensitive dye DAF FM-DA. NO production rose from 21 ± 7 to 58 ± 12 AU/min (P < 0.02; n = 7) when we increased luminal flow from 0 to 20 nl/min, but dropped to 16 ± 8 AU/min (P < 0.02; n = 7) 10 min after flow was stopped. Flow did not increase NO in tubules from mice lacking NO synthase 3 (NOS 3). Flow stimulated NO production by the same extent in tubules perfused with ion-free solution and physiological saline (20 ± 7 vs. 24 ± 6 AU/min; n = 7). Increasing stretch while reducing shear stress and pressure lowered NO generation from 42 ± 9 to 17 ± 6 AU/min (P < 0.03; n = 6). In the absence of shear stress, increasing pressure and stretch had no effect on NO production (2 ± 8 vs. 8 ± 8 AU/min; n = 6). Similar results were obtained in the presence of tempol (100 μmol/l), a O2− scavenger. Primary cultures of thick ascending limb cells subjected to shear stresses of 0.02 and 0.55 dyne/cm2 produced NO at rates of 55 ± 10 and 315 ± 93 AU/s, respectively (P < 0.002; n = 7). Pretreatment with the NOS inhibitor l-NAME (5 mmol/l) blocked the shear stress-induced increase in NO production. We concluded that shear stress rather than pressure, stretch, or ion delivery mediates flow-induced stimulation of NO by NOS 3 in thick ascending limbs. PMID:20719980

Boundary layers at the interface of two different shear flows

NASA Astrophysics Data System (ADS)

Weidman, Patrick D.; Wang, C. Y.

2018-05-01

We present solutions for the boundary layer between two uniform shear flows flowing in the same direction. In the upper layer, the flow has shear strength a, fluid density ρ1, and kinematic viscosity ν1, while the lower layer has shear strength b, fluid density ρ2, and kinematic viscosity ν2. Similarity transformations reduce the boundary-layer equations to a pair of ordinary differential equations governed by three dimensionless parameters: the shear strength ratio γ = b/a, the density ratio ρ = ρ2/ρ1, and the viscosity ratio ν = ν2/ν1. Further analysis shows that an affine transformation reduces this multi-parameter problem to a single ordinary differential equation which may be efficiently integrated as an initial-value problem. Solutions of the original boundary-value problem are shown to agree with the initial-value integrations, but additional dual and quadruple solutions are found using this method. We argue on physical grounds and through bifurcation analysis that these additional solutions are not tenable. The present problem is applicable to the trailing edge flow over a thin airfoil with camber.

Nucleation of protein crystals under the influence of solution shear flow.

PubMed

Penkova, Anita; Pan, Weichun; Hodjaoglu, Feyzim; Vekilov, Peter G

2006-09-01

Several recent theories and simulations have predicted that shear flow could enhance, or, conversely, suppress the nucleation of crystals from solution. Such modulations would offer a pathway for nucleation control and provide a novel explanation for numerous mysteries in nucleation research. For experimental tests of the effects of shear flow on protein crystal nucleation, we found that if a protein solution droplet of approximately 5 microL (2-3 mm diameter at base) is held on a hydrophobic substrate in an enclosed environment and in a quasi-uniform constant electric field of 2 to 6 kV cm(-1), a rotational flow with a maximum rate at the droplet top of approximately 10 microm s(-1) is induced. The shear rate varies from 10(-3) to 10(-1) s(-1). The likely mechanism of the rotational flow involves adsorption of the protein and amphiphylic buffer molecules on the air-water interface and their redistribution in the electric field, leading to nonuniform surface tension of the droplet and surface tension-driven flow. Observations of the number of nucleated crystals in 24- and 72-h experiments with the proteins ferritin, apoferritin, and lysozyme revealed that the crystals are typically nucleated at a certain radius of the droplet, that is, at a preferred shear rate. Variations of the rotational flow velocity resulted in suppression or enhancement of the total number of nucleated crystals of ferritin and apoferritin, while all solution flow rates were found to enhance lysozyme crystal nucleation. These observations show that shear flow may strongly affect nucleation, and that for some systems, an optimal flow velocity, leading to fastest nucleation, exists. Comparison with the predictions of theories and simulations suggest that the formation of ordered nuclei in a "normal" protein solution cannot be affected by such low shear rates. We conclude that the flow acts by helping or suppressing the formation of ordered nuclei within mesoscopic metastable dense liquid clusters. Such clusters were recently shown to exist in protein solutions and to constitute the first step in the nucleation mechanism of many protein and nonproteinsystems.

Shear Wave Imaging of Breast Tissue by Color Doppler Shear Wave Elastography.

PubMed

Yamakoshi, Yoshiki; Nakajima, Takahito; Kasahara, Toshihiro; Yamazaki, Mayuko; Koda, Ren; Sunaguchi, Naoki

2017-02-01

Shear wave elastography is a distinctive method to access the viscoelastic characteristic of the soft tissue that is difficult to obtain by other imaging modalities. This paper proposes a novel shear wave elastography [color Doppler shear wave imaging (CD SWI)] for breast tissue. Continuous shear wave is produced by a small lightweight actuator, which is attached to the tissue surface. Shear wave wavefront that propagates in tissue is reconstructed as a binary pattern that consists of zero and the maximum flow velocities on color flow image (CFI). Neither any modifications of the ultrasound color flow imaging instrument nor a high frame rate ultrasound imaging instrument is required to obtain the shear wave wavefront map. However, two conditions of shear wave displacement amplitude and shear wave frequency are needed to obtain the map. However, these conditions are not severe restrictions in breast imaging. This is because the minimum displacement amplitude is [Formula: see text] for an ultrasonic wave frequency of 12 MHz and the shear wave frequency is available from several frequencies suited for breast imaging. Fourier analysis along time axis suppresses clutter noise in CFI. A directional filter extracts shear wave, which propagates in the forward direction. Several maps, such as shear wave phase, velocity, and propagation maps, are reconstructed by CD SWI. The accuracy of shear wave velocity measurement is evaluated for homogeneous agar gel phantom by comparing with the acoustic radiation force impulse method. The experimental results for breast tissue are shown for a shear wave frequency of 296.6 Hz.

Response of hot element flush wall gauges in oscillating laminar flow

NASA Technical Reports Server (NTRS)

Giddings, T. A.; Cook, W. J.

1986-01-01

The time dependent response characteristics of flush-mounted hot element gauges used as instruments to measure wall shear stress in unsteady periodic air flows were investigated. The study was initiated because anomalous results were obtained from the gauges in oscillating turbulent flows for the phase relation of the wall shear stress variation, indicating possible gauge response problems. Flat plate laminar oscillating turbulent flows characterized by a mean free stream velocity with a superposed sinusoidal variation were performed. Laminar rather than turbulent flows were studied, because a numerical solution for the phase angle between the free stream velocity and the wall shear stress variation that is known to be correct can be obtained. The focus is on comparing the phase angle indicated by the hot element gauges with corresponding numerical prediction for the phase angle, since agreement would indicate that the hot element gauges faithfully follow the true wall shear stress variation.

Dynamical properties of nematic liquid crystals subjected to shear flow and magnetic fields: tumbling instability and nonequilibrium fluctuations.

PubMed

Fatriansyah, Jaka Fajar; Orihara, Hiroshi

2013-07-01

We investigate the dynamical properties of monodomain nematic liquid crystals under shear flow and magnetic fields on the basis of the Ericksen-Leslie theory. Stable and unstable states appear depending on the magnetic field and the shear rate. The trajectory of the unstable state shows tumbling motion. The phase diagram of these states is plotted as a function of the three components of the magnetic field at a constant shear rate. The phase diagram changes depending on the viscous properties of different types of nematic liquid crystals. In this nonequilibrium steady state, we calculate the correlation function of director fluctuations and the response function, and discuss the nonequilibrium fluctuations and the modified fluctuation-dissipation relation in connection with nonconservative forces due to shear flow.

In situ monitoring of localized shear stress and fluid flow within developing tissue constructs by Doppler optical coherence tomography

NASA Astrophysics Data System (ADS)

Jia, Yali; Bagnaninchi, Pierre O.; Wang, Ruikang K.

2008-02-01

Mechanical stimuli can be introduced to three dimensional (3D) cell cultures by use of perfusion bioreactor. Especially in musculoskeletal tissues, shear stress caused by fluid flow generally increase extra-cellular matrix (ECM) production and cell proliferation. The relationship between the shear stress and the tissue development in situ is complicated because of the non-uniform pore distribution within the cell-seeded scaffold. In this study, we firstly demonstrated that Doppler optical coherence tomography (DOCT) is capable of monitoring localized fluid flow and shear stress in the complex porous scaffold by examining their variation trends at perfusion rate of 5, 8, 10 and 12 ml/hr. Then, we developed the 3D porous cellular constructs, cell-seeded chitosan scaffolds monitored during several days by DOCT. The fiber based fourier domain DOCT employed a 1300 nm superluminescent diode with a bandwidth of 52 nm and a xyz resolution of 20×20×15 μm in free space. This setup allowed us not only to assess the cell growth and ECM deposition by observing their different scattering behaviors but also to further investigate how the cell attachment and ECM production has the effect on the flow shear stress and the relationship between flow rate and shear stress in the developing tissue construct. The possibility to monitor continuously the constructs under perfusion will easily indicate the effect of flow rate or shear stress on the cell viability and cell proliferation, and then discriminate the perfusion parameters affecting the pre-tissue formation rate growth.

Quantifying the effects of external shear loads on arterial and venous blood flow: implications for pressure ulcer development.

PubMed

Manorama, Abinand; Meyer, Ronald; Wiseman, Robert; Bush, Tamara Reid

2013-06-01

Forces applied to the skin cause a decrease in regional blood flow. This decrease in blood flow can cause tissue necrosis and lead to the formation of deep, penetrating wounds called pressure ulcers. These wounds are detrimental to individuals with compromised health, such as the elderly and spinal-cord injured. Although surface pressure is known to be a primary risk factor for developing a pressure ulcer, a seated individual rarely experiences pressure alone but rather combined loading which includes pressure as well as shear force on the skin. However, little research has been conducted to quantify the effects of shear forces on blood flow. Fifteen men were tested in a magnetic resonance imaging scanner under no load, a normal load, and a combination of normal and shear loads. Changes in arterial and venous blood flow in the forearm were measured using magnetic resonance angiography phase-contrast imaging. The blood flow in the anterior interosseous artery and basilic vein of the forearm decreased with the application of normal loads, and decreased further with the addition of shear loads. Marginal to significant differences at a 90% confidence level (P=0.08, 0.10) were observed, and medium to high effect sizes (0.3 to 0.5) were obtained. Based on these results, shear force is an important factor to consider in relation to pressure ulcer propagation and prevention, and hence, future prevention approaches should also focus on mitigating shear loads. Copyright © 2013 Elsevier Ltd. All rights reserved.

Sustained expression of MCP-1 by low wall shear stress loading concomitant with turbulent flow on endothelial cells of intracranial aneurysm.

PubMed

Aoki, Tomohiro; Yamamoto, Kimiko; Fukuda, Miyuki; Shimogonya, Yuji; Fukuda, Shunichi; Narumiya, Shuh

2016-05-09

Enlargement of a pre-existing intracranial aneurysm is a well-established risk factor of rupture. Excessive low wall shear stress concomitant with turbulent flow in the dome of an aneurysm may contribute to progression and rupture. However, how stress conditions regulate enlargement of a pre-existing aneurysm remains to be elucidated. Wall shear stress was calculated with 3D-computational fluid dynamics simulation using three cases of unruptured intracranial aneurysm. The resulting value, 0.017 Pa at the dome, was much lower than that in the parent artery. We loaded wall shear stress corresponding to the value and also turbulent flow to the primary culture of endothelial cells. We then obtained gene expression profiles by RNA sequence analysis. RNA sequence analysis detected hundreds of differentially expressed genes among groups. Gene ontology and pathway analysis identified signaling related with cell division/proliferation as overrepresented in the low wall shear stress-loaded group, which was further augmented by the addition of turbulent flow. Moreover, expression of some chemoattractants for inflammatory cells, including MCP-1, was upregulated under low wall shear stress with concomitant turbulent flow. We further examined the temporal sequence of expressions of factors identified in an in vitro study using a rat model. No proliferative cells were detected, but MCP-1 expression was induced and sustained in the endothelial cell layer. Low wall shear stress concomitant with turbulent flow contributes to sustained expression of MCP-1 in endothelial cells and presumably plays a role in facilitating macrophage infiltration and exacerbating inflammation, which leads to enlargement or rupture.

Factors affecting shear thickening behavior of a concentrated injectable suspension of levodopa.

PubMed

Allahham, Ayman; Stewart, Peter; Marriott, Jennifer; Mainwaring, David

2005-11-01

Previous clinical studies on a subcutaneous injectable suspension of levodopa showed poor injectability into human tissue. When this formulation was rheologically characterised, a clinical shear thickening interval was observed at increased shear rates. The formulation parameters that contributed to this rheological behavior were systematically evaluated with the aim of removing this flow limitation while maintaining the concentration of 60% levodopa to retain the clinical applicability. The three suspension parameters examined were: levodopa volume fraction, concentration of the HPMC suspending vehicle, and particle size distribution. Shear thickening increased with the drug concentration and the critical shear rate was inversely dependent on the drug concentration. Increasing the vehicle concentration retarded the shear thickening but increased the overall suspension viscosity. There was an increase in shear thickening with increased average particle diameter. Combinations of micronized and non-micronized particles were used to prepare bimodal particle size distributions. The rheology of these bimodal distributions resulted in removal of shear thickening. This allowed the preparation of 60% levodopa formulations that showed a range of flow characteristics spanning near Newtonian flow or shear thinning at initial injectable viscosities of about 0.6 Pa.s and final viscosities in the range of 0.1 Pa.s, alleviating the shear thickening limitation of these levodopa formulations.

Ballooning instabilities in tokamaks with sheared toroidal flows

DOE Office of Scientific and Technical Information (OSTI.GOV)

Waelbroeck, F.L.; Chen, L.

1990-11-01

The stability of ballooning modes in the presence of sheared toroidal flows is investigated. The eigenmodes are shown to be related by a Fourier transformation to the non-exponentially growing Floquet solutions found by Cooper. It is further shown that the problem cannot be reduced further than to a two dimensional partial differential equation. Next, the generalized ballooning equation is solved analytically for a circular tokamak equilibrium with sonic flows, but with a small rotation shear compared to the sound speed. With this ordering, the centrifugal forces are comparable to the pressure gradient forces driving the instability, but coupling of themore » mode with the sound wave is avoided. A new stability criterion is derived which explicitly demonstrates that flow shear is stabilizing at constant centrifugal force gradient. 34 refs.« less

Wall shear stress estimates in coronary artery constrictions

NASA Technical Reports Server (NTRS)

Back, L. H.; Crawford, D. W.

1992-01-01

Wall shear stress estimates from laminar boundary layer theory were found to agree fairly well with the magnitude of shear stress levels along coronary artery constrictions obtained from solutions of the Navier Stokes equations for both steady and pulsatile flow. The relatively simple method can be used for in vivo estimates of wall shear stress in constrictions by using a vessel shape function determined from a coronary angiogram, along with a knowledge of the flow rate.

In vitro Flow Adhesion Assay for Analyzing Shear-resistant Adhesion of Metastatic Cancer Cells to Endothelial Cells.

PubMed

Kang, Shin-Ae; Bajana, Sandra; Tanaka, Takemi

2016-02-20

Hematogenous metastasis is a primary cause of mortality from metastatic cancer. The shear-resistant adhesion of circulating tumor cells to the vascular endothelial cell surface under blood flow is an essential step in cell extravasation and further tissue invasion. This is similar to a process exploited by leukocytes for adhesion to inflamed blood vessels (leukocyte mimicry). The shear resistant adhesion is mediated by high affinity interactions between endothelial adhesion molecules and their counter receptor ligand expressed on circulating cells. Thus, weak interaction results in a rapid detachment of circulating cells from endothelium. Despite the critical role of vascular adhesion of cancer cells in hematogenous metastasis, our knowledge regarding this process has been limited due to the difficulty of mimicking dynamic flow conditions in vitro . In order to gain better insight into the shear-resistant adhesion of cancer cells to the endothelium, we developed a protocol for measuring the shear resistant adhesion of circulating tumor cells to endothelial cells under physiologic flow conditions by adapting a well established flow adhesion assay for inflammatory cells. This technique is useful to evaluate 1) the shear resistant adhesion competency of cancer cells and 2) the endothelial adhesion molecules necessary to support cancer cell adhesion (Kang et al. , 2015).

Experimental investigation of flow and slip transition in nanochannels

NASA Astrophysics Data System (ADS)

Li, Zhigang; Li, Long; Mo, Jingwen

2014-11-01

Flow slip in nanochannels is sought in many applications, such as sea water desalination and molecular separation, because it can enhance fluid transport, which is essential in nanofluidic systems. Previous findings about the slip length for simple fluids at the nanoscale appear to be controversial. Some experiments and simulations showed that the slip length is independent of shear rate, which agrees with the prediction of classic slip theories. However, there is increasing work showing that slip length is shear rate dependent. In this work, we experimentally investigate the Poiseuille flows in nanochannels. It is found that the flow rate undergoes a transition between two linear regimes as the shear rate is varied. The transition indicates that the non-slip boundary condition is valid at low shear rate. When the shear rate is larger than a critical value, slip takes place and the slip length increases linearly with increasing shear rate before approaching a constant value. The results reported in this work can help advance the understanding of flow slip in nanochannels. This work was supported by the Research Grants Council of the Hong Kong Special Administrative Region under Grant Nos. 615710 and 615312. J. Mo was partially supported by the Postgraduate Scholarship through the Energy Program at HKUST.

A film-based wall shear stress sensor for wall-bounded turbulent flows

NASA Astrophysics Data System (ADS)

Amili, Omid; Soria, Julio

2011-07-01

In wall-bounded turbulent flows, determination of wall shear stress is an important task. The main objective of the present work is to develop a sensor which is capable of measuring surface shear stress over an extended region applicable to wall-bounded turbulent flows. This sensor, as a direct method for measuring wall shear stress, consists of mounting a thin flexible film on the solid surface. The sensor is made of a homogeneous, isotropic, and incompressible material. The geometry and mechanical properties of the film are measured, and particles with the nominal size of 11 μm in diameter are embedded on the film's surface to act as markers. An optical technique is used to measure the film deformation caused by the flow. The film has typically deflection of less than 2% of the material thickness under maximum loading. The sensor sensitivity can be adjusted by changing the thickness of the layer or the shear modulus of the film's material. The paper reports the sensor fabrication, static and dynamic calibration procedure, and its application to a fully developed turbulent channel flow at Reynolds numbers in the range of 90,000-130,000 based on the bulk velocity and channel full height. The results are compared to alternative wall shear stress measurement methods.

Flow induced crystallisation of penetrable particles

NASA Astrophysics Data System (ADS)

Scacchi, Alberto; Brader, Joseph M.

2018-03-01

For a system of Brownian particles interacting via a soft exponential potential we investigate the interaction between equilibrium crystallisation and spatially varying shear flow. For thermodynamic state points within the liquid part of the phase diagram, but close to the crystallisation phase boundary, we observe that imposing a Poiseuille flow can induce nonequilibrium crystalline ordering in regions of low shear gradient. The physical mechanism responsible for this phenomenon is shear-induced particle migration, which causes particles to drift preferentially towards the center of the flow channel, thus increasing the local density in the channel center. The method employed is classical dynamical density functional theory.

Flow induced crystallisation of penetrable particles.

PubMed

Scacchi, Alberto; Brader, Joseph M

2018-03-07

For a system of Brownian particles interacting via a soft exponential potential we investigate the interaction between equilibrium crystallisation and spatially varying shear flow. For thermodynamic state points within the liquid part of the phase diagram, but close to the crystallisation phase boundary, we observe that imposing a Poiseuille flow can induce nonequilibrium crystalline ordering in regions of low shear gradient. The physical mechanism responsible for this phenomenon is shear-induced particle migration, which causes particles to drift preferentially towards the center of the flow channel, thus increasing the local density in the channel center. The method employed is classical dynamical density functional theory.

Studies in turbulence

NASA Technical Reports Server (NTRS)

Gatski, Thomas B. (Editor); Sarkar, Sutanu (Editor); Speziale, Charles G. (Editor)

1992-01-01

Various papers on turbulence are presented. Individual topics addressed include: modeling the dissipation rate in rotating turbulent flows, mapping closures for turbulent mixing and reaction, understanding turbulence in vortex dynamics, models for the structure and dynamics of near-wall turbulence, complexity of turbulence near a wall, proper orthogonal decomposition, propagating structures in wall-bounded turbulence flows. Also discussed are: constitutive relation in compressible turbulence, compressible turbulence and shock waves, direct simulation of compressible turbulence in a shear flow, structural genesis in wall-bounded turbulence flows, vortex lattice structure of turbulent shear slows, etiology of shear layer vortices, trilinear coordinates in fluid mechanics.

Flooding Experiments and Modeling for Improved Reactor Safety

DOE Office of Scientific and Technical Information (OSTI.GOV)

Solmos, M.; Hogan, K. J.; Vierow, K.

2008-09-14

Countercurrent two-phase flow and “flooding” phenomena in light water reactor systems are being investigated experimentally and analytically to improve reactor safety of current and future reactors. The aspects that will be better clarified are the effects of condensation and tube inclination on flooding in large diameter tubes. The current project aims to improve the level of understanding of flooding mechanisms and to develop an analysis model for more accurate evaluations of flooding in the pressurizer surge line of a Pressurized Water Reactor (PWR). Interest in flooding has recently increased because Countercurrent Flow Limitation (CCFL) in the AP600 pressurizer surge linemore » can affect the vessel refill rate following a small break LOCA and because analysis of hypothetical severe accidents with the current flooding models in reactor safety codes shows that these models represent the largest uncertainty in analysis of steam generator tube creep rupture. During a hypothetical station blackout without auxiliary feedwater recovery, should the hot leg become voided, the pressurizer liquid will drain to the hot leg and flooding may occur in the surge line. The flooding model heavily influences the pressurizer emptying rate and the potential for surge line structural failure due to overheating and creep rupture. The air-water test results in vertical tubes are presented in this paper along with a semi-empirical correlation for the onset of flooding. The unique aspects of the study include careful experimentation on large-diameter tubes and an integrated program in which air-water testing provides benchmark knowledge and visualization data from which to conduct steam-water testing.« less

"Reagentless" flow injection determination of ammonia and urea using membrane separation and solid phase basification

NASA Technical Reports Server (NTRS)

Akse, J. R.; Thompson, J. O.; Sauer, R. L.; Atwater, J. E.

1998-01-01

Flow injection analysis instrumentation and methodology for the determination of ammonia and ammonium ions in an aqueous solution are described. Using in-line solid phase basification beds containing crystalline media. the speciation of ammoniacal nitrogen is shifted toward the un-ionized form. which diffuses in the gas phase across a hydrophobic microporous hollow fiber membrane into a pure-water-containing analytical stream. The two streams flow in a countercurrent configuration on opposite sides of the membrane. The neutral pH of the analytical stream promotes the formation of ammonium cations, which are detected using specific conductance. The methodology provides a lower limit of detection of 10 microgram/L and a dynamic concentration range spanning three orders of magnitude using a 315-microliters sample injection volume. Using immobilized urease to enzymatically promote the hydrolysis of urea to produce ammonia and carbon dioxide, the technique has been extended to the determination of urea.

Disturbed flow mediated modulation of shear forces on endothelial plane: A proposed model for studying endothelium around atherosclerotic plaques

NASA Astrophysics Data System (ADS)

Balaguru, Uma Maheswari; Sundaresan, Lakshmikirupa; Manivannan, Jeganathan; Majunathan, Reji; Mani, Krishnapriya; Swaminathan, Akila; Venkatesan, Saravanakumar; Kasiviswanathan, Dharanibalan; Chatterjee, Suvro

2016-06-01

Disturbed fluid flow or modulated shear stress is associated with vascular conditions such as atherosclerosis, thrombosis, and aneurysm. In vitro simulation of the fluid flow around the plaque micro-environment remains a challenging approach. Currently available models have limitations such as complications in protocols, high cost, incompetence of co-culture and not being suitable for massive expression studies. Hence, the present study aimed to develop a simple, versatile model based on Computational Fluid Dynamics (CFD) simulation. Current observations of CFD have shown the regions of modulated shear stress by the disturbed fluid flow. To execute and validate the model in real sense, cell morphology, cytoskeletal arrangement, cell death, reactive oxygen species (ROS) profile, nitric oxide production and disturbed flow markers under the above condition were assessed. Endothelium at disturbed flow region which had been exposed to low shear stress and swirling flow pattern showed morphological and expression similarities with the pathological disturbed flow environment reported previously. Altogether, the proposed model can serve as a platform to simulate the real time micro-environment of disturbed flow associated with eccentric plaque shapes and the possibilities of studying its downstream events.

A rational approach to the use of Prandtl's mixing length model in free turbulent shear flow calculations

NASA Technical Reports Server (NTRS)

Rudy, D. H.; Bushnell, D. M.

1973-01-01

Prandtl's basic mixing length model was used to compute 22 test cases on free turbulent shear flows. The calculations employed appropriate algebraic length scale equations and single values of mixing length constant for planar and axisymmetric flows, respectively. Good agreement with data was obtained except for flows, such as supersonic free shear layers, where large sustained sensitivity changes occur. The inability to predict the more gradual mixing in these flows is tentatively ascribed to the presence of a significant turbulence-induced transverse static pressure gradient which is neglected in conventional solution procedures. Some type of an equation for length scale development was found to be necessary for successful computation of highly nonsimilar flow regions such as jet or wake development from thick wall flows.

Modeling changes in rill erodibility and critical shear stress on native surface roads

Treesearch

Randy B. Foltz; Hakjun Rhee; William J. Elliot

2008-01-01

This study investigated the effect of cumulative overland flow on rill erodibility and critical shear stress on native surface roads in central Idaho. Rill erodibility decreased exponentially with increasing cumulative overland flow depth; however, critical shear stress did not change. The study demonstrated that road erodibility on the studied road changes over the...

The Effect of Symmetry on the Hydrodynamic Stability of and Bifurcation from Planar Shear Flows

DTIC Science & Technology

1990-12-01

Effect of Symmetry on the Hydrodynamic Stability of ant Bifurcation from Planar Shear Flows AFOSR-88-0196 6. AUTHOR(S) 61102F 2304/A4 Thomas J. Bridges 7...December 1990 The Effect of Symmetry on the Hydrodynamic Stability of and Bifurcation from Planar Shear Flows TIIhOMAS J. BIUDGES MATl EM ATIc(AL...spatial stabili’.y into the nonlinear regime and a theory for spa- tial Hopf bifurcation , spatial Floquet theory, wavelength doubling and spatially quasi

An alternative assessment of second-order closure models in turbulent shear flows

NASA Technical Reports Server (NTRS)

Speziale, Charles G.; Gatski, Thomas B.

1994-01-01

The performance of three recently proposed second-order closure models is tested in benchmark turbulent shear flows. Both homogeneous shear flow and the log-layer of an equilibrium turbulent boundary layer are considered for this purpose. An objective analysis of the results leads to an assessment of these models that stands in contrast to that recently published by other authors. A variety of pitfalls in the formulation and testing of second-order closure models are uncovered by this analysis.

On shapes and motion of an elongated bubble in downward liquid pipe flow

NASA Astrophysics Data System (ADS)

Fershtman, A.; Babin, V.; Barnea, D.; Shemer, L.

2017-11-01

In stagnant liquid, or in a steady upward liquid pipe flow, an elongated (Taylor) bubble has a symmetric shape. The translational velocity of the bubble is determined by buoyancy and the liquid velocity profile ahead of it. In downward flow, however, the symmetry of the bubble nose can be lost. Taylor bubble motion in downward flow is important in numerous applications such as chemical plants and cooling systems that often contain countercurrent gas-liquid flow. In the present study, the relation between the Taylor bubble shape and its translational velocity is investigated experimentally in a vertical pipe for various downward liquid flow rates. At higher downward velocities, the bubble may be forced by the background flow to propagate downward against buoyancy. In order to include those cases as well in our experimental analysis, the bubbles were initially injected into stagnant liquid, whereas the downward flow was initiated at a later stage. This experimental procedure allowed us to identify three distinct modes of translational velocities for a given downward background liquid flow; each velocity corresponds to a different bubble shape. Hydrodynamic mechanisms that govern the transition between the modes observed in the present study are discussed.

Velocity and void distribution in a counter-current two-phase flow

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gabriel, S.; Schulenberg, T.; Laurien, E.

2012-07-01

Different flow regimes were investigated in a horizontal channel. Simulating a hot leg injection in case of a loss of coolant accident or flow conditions in reflux condenser mode, the hydraulic jump and partially reversed flow were identified as major constraints for a high amount of entrained water. Trying to simulate the reflux condenser mode, the test section now includes an inclined section connected to a horizontal channel. The channel is 90 mm high and 110 mm wide. Tests were carried out for water and air at ambient pressure and temperature. High speed video-metry was applied to obtain velocities frommore » flow pattern maps of the rising and falling fluid. In the horizontal part of the channel with partially reversed flow the fluid velocities were measured by planar particle image velocimetry. To obtain reliable results for the gaseous phase, this analysis was extended by endoscope measurements. Additionally, a new method based on the optical refraction at the interface between air and water in a back-light was used to obtain time-averaged void fraction. (authors)« less

Generation of parasitic axial flow by drift wave turbulence with broken symmetry: Theory and experiment

NASA Astrophysics Data System (ADS)

Hong, R.; Li, J. C.; Hajjar, R.; Chakraborty Thakur, S.; Diamond, P. H.; Tynan, G. R.

2018-05-01

Detailed measurements of intrinsic axial flow generation parallel to the magnetic field in the controlled shear decorrelation experiment linear plasma device with no axial momentum input are presented and compared to theory. The results show a causal link from the density gradient to drift-wave turbulence with broken spectral symmetry and development of the axial mean parallel flow. As the density gradient steepens, the axial and azimuthal Reynolds stresses increase and radially sheared azimuthal and axial mean flows develop. A turbulent axial momentum balance analysis shows that the axial Reynolds stress drives the radially sheared axial mean flow. The turbulent drive (Reynolds power) for the azimuthal flow is an order of magnitude greater than that for axial flow, suggesting that the turbulence fluctuation levels are set by azimuthal flow shear regulation. The direct energy exchange between axial and azimuthal mean flows is shown to be insignificant. Therefore, the axial flow is parasitic to the turbulence-zonal flow system and is driven primarily by the axial turbulent stress generated by that system. The non-diffusive, residual part of the axial Reynolds stress is found to be proportional to the density gradient and is formed due to dynamical asymmetry in the drift-wave turbulence.

Seasonal Variability in Regional Ice Flow Due to Meltwater Injection Into the Shear Margins of Jakobshavn Isbræ

NASA Astrophysics Data System (ADS)

Cavanagh, J. P.; Lampkin, D. J.; Moon, T.

2017-12-01

The impact of meltwater injection into the shear margins of Jakobshavn Isbræ via drainage from water-filled crevasses on ice flow is examined. We use Landsat-8 Operational Land Imager panchromatic, high-resolution imagery to monitor the spatiotemporal variability of seven water-filled crevasse ponds during the summers of 2013 to 2015. The timing of drainage from water-filled crevasses coincides with an increase of 2 to 20% in measured ice velocity beyond Jakobshavn Isbræ shear margins, which we define as extramarginal ice velocity. Some water-filled crevasse groups demonstrate multiple drainage events within a single melt season. Numerical simulations show that hydrologic shear weakening due to water-filled crevasse drainage can accelerate extramarginal flow by as much as 35% within 10 km of the margins and enhance mass flux through the shear margins by 12%. This work demonstrates a novel mechanism through which surface melt can influence regional ice flow.

Orientation distribution of sheared isotactic polypropylene plates through thickness in the presence of sodium benzoate

NASA Astrophysics Data System (ADS)

Zhu, Peng-wei; Phillips, Andrew; Tung, Jason; Edward, Graham

2005-05-01

The orientation distribution of sheared isotactic polypropylene (iPP) containing different amount of sodium benzoate (SB) has been investigated through the gradient of shear flow field using microbeam of synchrotron wide-angle x-ray techniques. The degree of the overall orientation of α-phase crystal is found to increase with increasing concentration of SB. Compared with the sheared iPP in the absence of SB, the orientation of α-phase crystal is found to distribute over a broader range of shear flow field in the presence of SB. The overall orientation of α-phase crystal is explained in terms of a parent-daughter model or lamella-branched shish-kebab structure. As the concentration of SB increases, the contribution from the c-axis orientation of parent lamellae decreases in the flow direction. The contribution from the a*-axis orientation of daughter lamellae is developed to be dominant in the flow direction when the concentration of SB exceeds a critical value.

Effects of wall curvature on turbulence statistics

NASA Technical Reports Server (NTRS)

Moser, R. D.; Moin, P.

1985-01-01

A three-dimensional, time-dependent, direct numerical simulation of low-Reynolds number turbulent flow in a mildly curved channel was performed, and the results examined to determine the mechanism by which curvature affects wall-bounded turbulent shear flows. A spectral numerical method with about one-million modes was employed, and no explicit subgrid scale model was used. The effects of curvature on this flow were determined by comparing the concave and convex sides of the channel. The observed effects are consistent with experimental observations for mild curvature. The most significant difference in the turbulence statistics between the concave and convex sides is in the Reynolds shear stress. This is accompanied by significant differences in the terms of the Reynolds shear stress balance equations. In addition, it was found that stationary Taylor-Goertler vortices were present and that they had a significant effect on the flow by contributing to the mean Reynolds shear stress, and by enhancing the difference between the wall shear stresses.

Periodic magnetorotational dynamo action as a prototype of nonlinear magnetic-field generation in shear flows.

PubMed

Herault, J; Rincon, F; Cossu, C; Lesur, G; Ogilvie, G I; Longaretti, P-Y

2011-09-01

The nature of dynamo action in shear flows prone to magnetohydrodynamc instabilities is investigated using the magnetorotational dynamo in Keplerian shear flow as a prototype problem. Using direct numerical simulations and Newton's method, we compute an exact time-periodic magnetorotational dynamo solution to three-dimensional dissipative incompressible magnetohydrodynamic equations with rotation and shear. We discuss the physical mechanism behind the cycle and show that it results from a combination of linear and nonlinear interactions between a large-scale axisymmetric toroidal magnetic field and nonaxisymmetric perturbations amplified by the magnetorotational instability. We demonstrate that this large-scale dynamo mechanism is overall intrinsically nonlinear and not reducible to the standard mean-field dynamo formalism. Our results therefore provide clear evidence for a generic nonlinear generation mechanism of time-dependent coherent large-scale magnetic fields in shear flows and call for new theoretical dynamo models. These findings may offer important clues to understanding the transitional and statistical properties of subcritical magnetorotational turbulence.

Simulations of blood flow through a stenosed carotid artery

NASA Astrophysics Data System (ADS)

Lundin, Staffan; Meder, Samuel; Metcalfe, Ralph

2000-11-01

The human carotid artery is often the site of the formation of atherosclerotic lesions that can lead to severe reduction of blood flow to the brain, frequently resulting in a stroke. There is strong evidence that hemodynamic variables such as the wall shear stress and its spatial and temporal derivatives play a role in fostering atherosclerosis. To investigate the potential of these effects, we have performed unsteady, three-dimensional numerical simulations of blood flow through the carotid bifurcation in the presence of stenoses of varying degrees and eccentricities. The simulations indicate that regions of low maximum and minimum shear stress correlate better with lesion prone sites than low average wall shear stress. As the degree of stenosis increases, it is found that the downstream flow changes drastically for stenoses greater than about 25Downstream eddies are generated during systole that create local shear stress peaks on the internal carotid artery wall, resulting in significant reduction in flow rates through the internal carotid artery. Large secondary flows develop, and there are also periods of flow reversal during the systolic/diastolic cycle.

A priori evaluation of the Pantano and Sarkar model in compressible homogeneous shear flows

NASA Astrophysics Data System (ADS)

Khlifi, Hechmi; Abdallah, J.; Aïcha, H.; Taïeb, L.

2011-01-01

In this study, a Reynolds stress closure, including the Pantano and Sarkar model of the mean part of the pressure-strain correlation is used for the computation of compressible homogeneous at high-speed shear flow. Several studies concerning the compressible homogeneous shear flow show that the changes of the turbulence structures are principally due to the structural compressibility effects which significantly affect the pressure field and then the pressure-strain correlation. Eventually, this term appears as the main term responsible for the changes in the magnitude of the Reynolds stress anisotropies. The structure of the gradient Mach number is similar to that of turbulence, therefore this parameter may be appropriate to study the changes in turbulence structures that arise from structural compressibility effects. Thus, the incompressible model of the pressure strain correlation and its corrected form by using the turbulent Mach turbulent only, fail to correctly evaluate the compressibility effects at high shear flow. An extension of the widely used incompressible Launder, Reece and Rodi model on compressible homogeneous shear flow is the major aim of the present work. From this extension, the standard coefficients C become a function of the extra compressibility parameters (the turbulent Mach number M and the gradient Mach number M) through the Pantano and Sarkar model. Application of the model on compressible homogeneous shear flow by considering various initial conditions shows reasonable agreement with the DNS results of Simone et al. and Sarkar. The observed trend of the dramatic increase in the normal Reynolds stress anisotropies, the significant decrease in the Reynolds shear stress anisotropy and the increase of the turbulent kinetic energy amplification rate with increasing the gradient Mach number are well predicted by the model. The ability of the model to predict the equilibrium states for the flow in cases A to A from DNS results of Sarkar is examined, the results appear to be very encouraging. Thus, both parameters M and M should be used to model significant structural compressibility effects at high-speed shear flow.

Purification of Proteins From Cell-Culture Medium or Cell-Lysate by High-Speed Counter-Current Chromatography Using Cross-Axis Coil Planet Centrifuge

PubMed Central

Shibusawa, Yoichi; Ito, Yoichiro

2014-01-01

This review describes protein purifications from cell culture medium or cell-lysate by high speed counter-current chromatography using the cross-axis coil planet centrifuge. Purifications were performed using aqueous two phase systems composed of polyethylene glycols and dextrans. PMID:25360182

SIMULATION OF NON-AZEOTROPIC REFRIGERANT MIXTURES FOR USE IN A DUAL-CIRCUIT REFRIGERATOR/FREEZER WITH COUNTERCURRENT HEAT EXCHANGES

EPA Science Inventory

The paper discusses a refrigerator/freezer (RF) system that has two complete and independent refrigeration cycles for the two compartments. It uses a non-azeotropic refrigerant mixture (NARM) in each cycle and countercurrent heat exchangers throughout. This RF is housed in a stan...

The effect of sheared toroidal rotation on pressure driven magnetic islands in toroidal plasmas

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hegna, C. C.

2016-05-15

The impact of sheared toroidal rotation on the evolution of pressure driven magnetic islands in tokamak plasmas is investigated using a resistive magnetohydrodynamics model augmented by a neoclassical Ohm's law. Particular attention is paid to the asymptotic matching data as the Mercier indices are altered in the presence of sheared flow. Analysis of the nonlinear island Grad-Shafranov equation shows that sheared flows tend to amplify the stabilizing pressure/curvature contribution to pressure driven islands in toroidal tokamaks relative to the island bootstrap current contribution. As such, sheared toroidal rotation tends to reduce saturated magnetic island widths.

Application of off-line two-dimensional high-performance countercurrent chromatography on the chloroform-soluble extract of Cuscuta auralis seeds.

PubMed

Rho, Taewoong; Yoon, Kee Dong

2018-05-01

In this study, the chloroform-soluble extract of Cuscuta auralis was separated successfully using off-line two-dimensional high-performance countercurrent chromatography, yielding a γ-pyrone, two alkaloids, a flavonoid, and four lignans. The first-dimensional countercurrent separation using a methylene chloride/methanol/water (11:6:5, v/v/v) system yielded three subfractions (fractions I-III). The second-dimensional countercurrent separations, conducted on fractions I-III using n-hexane/ethyl acetate/methanol/water/acetic acid (5:5:5:5:0, 3:7:3:7:0, and 1:9:1:9:0.01, v/v/v/v/v) systems, gave maltol (1), (-)-(13S)-cuscutamine (2), (+)-(13R)-cuscutamine (3), (+)-pinoresinol (4), (+)-epipinoresinol (5), kaempferol (6), piperitol (7), and (9R)-hydroxy-d-sesamin (8). To the best of our knowledge, maltol was identified for the first time in Cuscuta species. Furthermore, this report details the first full assignment of spectroscopic data of two cuscutamine epimers, (-)-(13S)-cuscutamine and (+)-(13R)-cuscutamine. © 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Dual-hologram shearing interference technique with regulated sensitivity

NASA Astrophysics Data System (ADS)

Toker, Gregory R.; Levin, Daniel

1998-06-01

A novel optical diagnostic technique,namely, a dual hologram shearing interferometry with regulated sensitivity, is proposed for visualization and measuring the density gradients of compressible flows in wind tunnels. It has advantages over conventional shearing interferometry in both accuracy and sensitivity. The method is especially useful for strong turbulent or unsteady regions of the flows including shock flows. The interferometer proved to be insensitive to mechanical vibrations and allowed to record holograms during the noisy wind tunnel run. The proposed approach was demonstrated by its application to a supersonic flow over spherically blunted and sharp nose cone/cylinder models. It is believed that the technique will become an effective tool for receiving optical data in many flow facilities.

Dual-hologram shearing interferometry with regulated sensitivity

NASA Astrophysics Data System (ADS)

Toker, Gregory R.; Levin, Daniel

1998-07-01

A novel optical diagnostic technique, namely, a dual hologram shearing interferometry with regulated sensitivity, is proposed for visualization and measuring the density gradients of compressible flows in wind tunnels. It has advantages over conventional shearing interferometry in both accuracy and sensitivity. The method is especially useful for strong turbulent or unsteady regions of the flows including shock flows. The interferometer proved to be insensitive to mechanical vibrations and allowed to record holograms during the noisy wind tunnel run. The proposed approach was demonstrated by its application to a supersonic flow over spherically blunted and sharp nose cone/cylinder models. It is believed that the technique will become an effective tool for receiving optical data in many flow facilities.

Turbulent shear layers in confining channels

NASA Astrophysics Data System (ADS)

Benham, Graham P.; Castrejon-Pita, Alfonso A.; Hewitt, Ian J.; Please, Colin P.; Style, Rob W.; Bird, Paul A. D.

2018-06-01

We present a simple model for the development of shear layers between parallel flows in confining channels. Such flows are important across a wide range of topics from diffusers, nozzles and ducts to urban air flow and geophysical fluid dynamics. The model approximates the flow in the shear layer as a linear profile separating uniform-velocity streams. Both the channel geometry and wall drag affect the development of the flow. The model shows good agreement with both particle image velocimetry experiments and computational turbulence modelling. The simplicity and low computational cost of the model allows it to be used for benchmark predictions and design purposes, which we demonstrate by investigating optimal pressure recovery in diffusers with non-uniform inflow.

Numerical simulation to determine the effects of incident wind shear and turbulence level on the flow around a building

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhang, Y.Q.; Huber, A.H.; Arya, S.P.S.

The effects of incident shear and turbulence on flow around a cubical building are being investigated by a turbulent kinetic energy/dissipation model (TEMPEST). The numerical simulations demonstrate significant effects due to the differences in the incident flow. The addition of upstream turbulence and shear results in a reduced size of the cavity directly behind the building. The accuracy of numerical simulations is verified by comparing the predicted mean flow fields with the available wind-tunnel measurements of Castro and Robins (1977). Comparing the authors' results with experimental data, the authors show that the TEMPEST model can reasonably simulate the mean flow.

Non-modal theory of the kinetic ion temperature gradient driven instability of plasma shear flows across the magnetic field

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mikhailenko, V. V., E-mail: vladimir@pusan.ac.kr; Mikhailenko, V. S.; Lee, Hae June, E-mail: haejune@pusan.ac.kr

2016-06-15

The temporal evolution of the kinetic ion temperature gradient driven instability and of the related anomalous transport of the ion thermal energy of plasma shear flow across the magnetic field is investigated analytically. This instability develops in a steady plasma due to the inverse ion Landau damping and has the growth rate of the order of the frequency when the ion temperature is equal to or above the electron temperature. The investigation is performed employing the non-modal methodology of the shearing modes which are the waves that have a static spatial structure in the frame of the background flow. Themore » solution of the governing linear integral equation for the perturbed potential displays that the instability experiences the non-modal temporal evolution in the shearing flow during which the unstable perturbation becomes very different from a canonical modal form. It transforms into the non-modal structure with vanishing frequency and growth rate with time. The obtained solution of the nonlinear integral equation, which accounts for the random scattering of the angle of the ion gyro-motion due to the interaction of ions with ensemble of shearing waves, reveals similar but accelerated process of the transformations of the perturbations into the zero frequency structures. It was obtained that in the shear flow the anomalous ion thermal conductivity decays with time. It is a strictly non-modal effect, which originates from the temporal evolution of the shearing modes turbulence.« less

Exploring Granular Flows at Intermediate Velocities

NASA Astrophysics Data System (ADS)

Brodsky, E. E.; van der Elst, N.

2012-12-01

Geophysical and geomorphological flows often encompass a wide range of strain rates. Landslides accelerate from nearly static conditions to velocities in the range of meters/seconds. The rheology of granular flows for the end-members is moderately well-understood, but the constitutive low at intermediate velocities is largely unexplored. Here we present evidence that granular flows transition through a regime in which internally generated acoustic waves play a critical role in controlling rheology. In laboratory experiments on natural sand under shear in a commercial rheometer, we observe that the steady-state flows at intermediate velocities are compacted relative to the end members. In a confined volume, this compaction results in a decrease in stress on the boundaries. We establish the key role of the acoustic waves by measuring the noise generated by the shear flows with an accelerometer and then exciting the flow with similar amplitude noise under lower shear rate conditions. The observed compaction for a given amplitude noise is the same in both cases, regardless of whether the noise is generated internally by the grains colliding or artificially applied externally. The boundaries of this acoustically controlled regime can be successfully predicted through non-dimensional analysis balancing the overburden, acoustic pressure and granular inertial terms. In our laboratory experiments, this regime corresponds to 0.1 to 10 cm/s. The controlling role of acoustic waves in intermediate velocities is significant because: (1) Geological systems must pass through this regime on their route to instability. (2) Acoustic waves are much more efficiently generated by angular particles, likely to be found in natural samples, than by perfectly spherical particles, which are more tractable for laboratory and theoretical studies. Therefore, this regime is likely to be missed in many analog and computational approaches. (3) Different mineralogies and shapes result in different noise generation. Therefore, there is a potential to extrapolate and predict rheological behavior of an active flow through studies of the recoverable granular products.Steady-state thickness vs. shear rate for angular sand and glass beads. Individual curves represent multiple up-going and down-going velocity ramps, and thick error bars show means and standard deviations between runs. Thickness is independent of shear rate at low shear rates, and strongly dependent on shear rate for intermediate and high shear rates. Compaction is observed at intermediate shear rates for angular sand, but not for smooth glass beads.

[?]Nonlinear Issues in the Aerothermochemistry of Gases and Materials and the Associated Physics and Dynamics of Interfaces

NASA Technical Reports Server (NTRS)

Johnson, Joseph A., III

1996-01-01

Our research and technology are focused on nonlinear issues in the aerothermochemistry of gases and materials and the associated physics and dynamics of interfaces. Our program is now organized to aggressively support the NASA Aeronautics Enterprise so as to: (a) develop a new generation of environmentally compatible, economic subsonic aircraft; (b) develop the technology base for an economically viable and environmentally compatible high-speed civil transport; (c) develop the technology options for new capabilities in high-performance aircraft; (d) develop hypersonic technologies for air-breathing flight; and (e) develop advanced concepts, understanding of physical phenomena, and theoretical, experimental, and computational tools for advanced aerospace systems. The implications from our research for aeronautical and aerospace technology have been both broad and deep. For example, using advanced computational techniques, we have determined exact solutions for the Schrodinger equation in electron-molecule scattering allowing us to evaluate atmospheric models important to reentry physics. We have also found a new class of exact solutions for the Navier Stokes equations. In experimental fluid dynamics, we have found explicit evidence of turbulence modification of droplet sizes in shock tube flow with condensation. We have developed a new diagnostic tool for the direct estimation of flow velocities at MHz sampling rates in quasi-one dimensional turbulent flow. This procedure suggests an unexpected confirmation of the possibility of 'natural' closure in Reynolds stresses with deep implications for the development of turbulent models. A transient increase is observed in both the spectral energy decay rate and the degree of chaotic complexity at the interface of a shock wave and a turbulent ionized gas. Even though the gas is apparently brought to rest by the shock wave, no evidence is found either of the expected relaminarization. A unique diamond-shaped nozzle has been designed for a detailed investigation of the effect of significant streamwise vorticity on the acoustic and IR characteristics of supersonic jets. Our results provide convincing evidence of the significant effect of vorticity on the far-field noise for the diamond jet as compared to the conventional round jets. We have found that the countercurrent shear layer mixes much more efficiently than conventional coflowing shear layers. We also developed the fluid thrust vectoring procedures which use counter flow to vector a jet. Our materials research has shown that the steep stress gradients at the fiber-matrix interface could be the primary cause of interface cracks after the processing of metallic and intermetallic matrix composites. New techniques have been evolved for: the microcharacterization of materials including microplastic strain and, point by point, the misorientation and plasticity for matrix composites; thermally induced stress measurements and load relaxation; the growth and characterization of metallic matrix composite interfaces; and for the growth of ferrite materials by pulsed laser deposition. The FAMU commitment to the HBCU Research Center also continues to be broad and deep.

Self-Diffusion of Drops in a Dilute Sheared Emulsion

NASA Technical Reports Server (NTRS)

Loewenberg, Michael; Hinch, E. J.

1996-01-01

Self-diffusion coefficients that describe cross-flow migration of non-Brownian drops in a dilute sheared emulsion were obtained by trajectory calculations. A boundary integral formulation was used to describe pairwise interactions between deformable drops; interactions between undeformed drops were described with mobility functions for spherical drops. The results indicate that drops have large anisotropic self-diffusivities which depend strongly on the drop viscosity and modestly on the shear-rate. Pairwise interactions between drops in shear-flow do not appreciably promote drop breakup.

Lattice Boltzmann Study of Bubbles on a Patterned Superhydrophobic Surface under Shear Flow

NASA Astrophysics Data System (ADS)

Chen, Wei; Wang, Kai; Hou, Guoxiang; Leng, Wenjun

2018-01-01

This paper studies shear flow over a 2D patterned superhydrophobic surface using lattice Boltzmann method (LBM). Single component Shan-Chen multiphase model and Carnahan-Starling EOS are adopted to handle the liquid-gas flow on superhydrophobic surface with entrapped micro-bubbles. The shape of bubble interface and its influence on slip length under different shear rates are investigated. With increasing shear rate, the bubble interface deforms. Then the contact lines are depinned from the slot edges and move downstream. When the shear rate is high enough, a continuous gas layer forms. If the protrusion angle is small, the gas layer forms and collapse periodically, and accordingly the slip length changes periodically. While if the protrusion angle is large, the gas layer is steady and separates the solid wall from liquid, resulting in a very large slip length.

An experimental study of combustion: The turbulent structure of a reacting shear layer formed at a rearward-facing step. Ph.D. Thesis. Final Report

NASA Technical Reports Server (NTRS)

Pitz, R. W.

1981-01-01

A premixed propane-air flame is stabilized in a turbulent free shear layer formed at a rearward-facing step. The mean and rms averages of the turbulent velocity flow field were determined by LDV for both reacting and non-reacting flows. The reaching flow was visualized by high speed schlieren photography. Large scale structures dominate the reacting shear layer. The growth of the large scale structures is tied to the propagation of the flame. The linear growth rate of the reacting shear layer defined by the mean velocity profiles is unchanged by combustion but the virtual origin is shifted downstream. The reacting shear layer based on the mean velocity profiles is shifted toward the recirculation zone and the reattachments lengths are shortened by 30%.

Local Turbulence Suppression and Shear Flow Dynamics During qmin-Triggered Internal Transport Barriers on DIII-D

NASA Astrophysics Data System (ADS)

Shafer, M. W.; McKee, G. R.; Schlossberg, D. J.; Austin, M. E.; Burrell, K. H.

2008-11-01

Long-wavelength turbulence (kρi< 1) is locally suppressed simultaneously with a rapid but transient increase in local poloidal flow shear at the appearance of low-order rational qmin surfaces in negative central shear discharges. At these events, reductions in energy transport are observed and Internal Transport Barriers (ITBs) may form. Application of off-axis ECH slows the q-profile evolution and increases ρqmin, both of which enhance turbulence measurements using a new high-sensitivity large-area (8x,8) 2D BES array. The measured transient turbulence suppression is localized to the low-order rational surface (qmin= 2, 5/2, 3, etc.). Measured poloidal flow shear transiently exceeds the turbulence decorrelation rate, which is consistent with shear suppression. The localized suppression zone propagates radially outward, nearly coincident with the low-order surface.

Calculation of free turbulent mixing by interaction approach.

NASA Technical Reports Server (NTRS)

Morel, T.; Torda, T. P.

1973-01-01

The applicability of Bradshaw's interaction hypothesis to two-dimensional free shear flows was investigated. According to it, flows with velocity extrema may be considered to consist of several interacting layers. The hypothesis leads to a new expression for the shear stress which removes the usual restriction that shear stress vanishes at the velocity extremum. The approach is based on kinetic energy and the length scale equations. The compressible flow equations are simplified by restriction to low Mach numbers, and the range of their applicability is discussed. The empirical functions of the turbulence model are found here to be correlated with the spreading rate of the shear layer. The analysis demonstrates that the interaction hypothesis is a workable concept.

Flow variation and substrate type affect dislodgement of the freshwater polychaete, Manayunkia speciosa

USGS Publications Warehouse

Malakauskas, David M.; Wilson, Sarah J.; Wilzbach, Margaret A.; Som, Nicholas A.

2013-01-01

We quantified microscale flow forces and their ability to entrain the freshwater polychaete, Manayunkia speciosa, the intermediate host for 2 myxozoan parasites (Ceratomyxa shasta and Parvicapsula minibicornis) that cause substantial mortalities in salmonid fishes in the Pacific Northwest. In a laboratory flume, we measured the shear stress associated with 2 mean flow velocities and 3 substrates and quantified associated dislodgement of polychaetes, evaluated survivorship of dislodged polychaetes, and observed behavioral responses of the polychaetes in response to increased flow. We used a generalized linear mixed model to estimate the probability of polychaete dislodgement for treatment combinations of velocity (mean flow velocity  =  55 cm/s with a shear velocity  =  3 cm/s, mean flow velocity  =  140 cm/s with a shear velocity  =  5 cm/s) and substrate type (depositional sediments and analogs of rock faces and the filamentous alga, Cladophora). Few polychaetes were dislodged at shear velocities <3 cm/s on any substrate. Above this level of shear, probability of dislodgement was strongly affected by both substrate type and velocity. After accounting for substrate, odds of dislodgement were 8× greater at the higher flow. After accounting for velocity, probability of dislodgement was greatest from fine sediments, intermediate from rock faces, and negligible from Cladophora. Survivorship of dislodged polychaetes was high. Polychaetes exhibited a variety of behaviors for avoiding increases in flow, including extrusion of mucus, burrowing into sediments, and movement to lower-flow microhabitats. Our findings suggest that polychaete populations probably exhibit high resilience to flow-mediated disturbances.

Edge-Induced Shear Banding in Entangled Polymeric Fluids.

PubMed

Hemingway, Ewan J; Fielding, Suzanne M

2018-03-30

Despite decades of research, the question of whether solutions and melts of highly entangled polymers exhibit shear banding as their steady state response to a steadily imposed shear flow remains controversial. From a theoretical viewpoint, an important unanswered question is whether the underlying constitutive curve of shear stress σ as a function of shear rate γ[over ˙] (for states of homogeneous shear) is monotonic, or has a region of negative slope, dσ/dγ[over ˙]<0, which would trigger banding. Attempts to settle the question experimentally via velocimetry of the flow field inside the fluid are often confounded by an instability of the free surface where the sample meets the outside air, known as "edge fracture." Here we show by numerical simulation that in fact even only very modest edge disturbances-which are the precursor of full edge fracture but might well, in themselves, go unnoticed experimentally-can cause strong secondary flows in the form of shear bands that invade deep into the fluid bulk. Crucially, this is true even when the underlying constitutive curve is monotonically increasing, precluding true bulk shear banding in the absence of edge effects.

Dynamics of micelle-nanoparticle systems undergoing shear. A coarse-grained molecular dynamics approach

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rolfe, Bryan A.; Chun, Jaehun; Joo, Yong L.

2013-09-05

Recent experimental work has shown that polymeric micelles can template nanoparticles via interstitial sites in shear-ordered micelle solutions. In the current study, we report simulation results based on a coarse-grained molecular dynamics (CGMD) model of a solvent/polymer/nanoparticle system. Our results demonstrate the importance of polymer concentration and the micelle corona length in 2D shear-ordering of neat block copolymer solutions. Although our results do not show strong 3D ordering during shear, we find that cessation of shear allows the system to relax into a 3D configuration of greater order than without shear. It is further shown that this post-shear relaxation ismore » strongly dependent on the length of the micelle corona. For the first time, we demonstrate the presence and importance of a flow disturbance surrounding micelles in simple shear flow at moderate Péclet numbers. This disturbance is similar to what is observed around simulated star polymers and ellipsoids. The extent of the flow disturbance increases as expected with a longer micelle corona length. It is further suggested that without proper consideration of these dynamics, a stable nanoparticle configuration would be difficult to obtain.« less

Kelvin-Helmholtz waves in extratropical cyclones passing over mountain ranges: KH Waves in Extratropical Cyclones over Mountain Ranges

DOE Office of Scientific and Technical Information (OSTI.GOV)

Medina, Socorro; Houze, Robert A.

2016-02-19

Kelvin–Helmholtz billows with horizontal scales of 3–4 km have been observed in midlatitude cyclones moving over the Italian Alps and the Oregon Cascades when the atmosphere was mostly statically stable with high amounts of shear and Ri < 0.25. In one case, data from a mobile radar located within a windward facing valley documented a layer in which the shear between down-valley flow below 1.2 km and strong upslope cross-barrier flow above was large. Several episodes of Kelvin–Helmholtz waves were observed within the shear layer. The occurrence of the waves appears to be related to the strength of the shear:more » when the shear attained large values, an episode of billows occurred, followed by a sharp decrease in the shear. The occurrence of large values of shear and Kelvin–Helmholtz billows over two different mountain ranges suggests that they may be important features occurring when extratropical cyclones with statically stable flow pass over mountain ranges.« less

Lubricant dynamics under sliding condition in disk drives

NASA Astrophysics Data System (ADS)

Wu, Lin

2006-07-01

In this paper, we develop a two-dimensional flow model for the lubricant flow dynamics under a sliding head in disk drives. Our two-dimensional model includes important physics such as viscous force, external air shearing stress, air bearing pressure, centrifugal force, disjoining pressure, and surface tension. Our analysis shows that the lubricant flow dynamics under the sliding condition is a fully two-dimensional phenomenon and the circumferential lubricant flow is strongly coupled to the radial flow. It is necessary to have a two-dimensional flow model that couples the circumferential and radial flows together and includes all important physics to achieve realistic predictions. Our results show that the external air shearing stress has a dominant effect on the lubricant flow dynamics. Both velocity slippage at wall and Poiseuille flow effects have to be considered in the evaluation of the air shearing stress under the head. The nonuniform air bearing pressure has a non-negligible effect on the lubricant film dynamics mostly through the Poiseuille flow effect on the air shearing stress but not from its direct pushing or sucking effect on the lubricant surface. Prediction of the formation of lubricant depletion tracks under a sliding head using the two-dimensional model agrees reasonably well with the existing experimental measurements.

A Parallel-Plate Flow Chamber for Mechanical Characterization of Endothelial Cells Exposed to Laminar Shear Stress

PubMed Central

Wong, Andrew K.; LLanos, Pierre; Boroda, Nickolas; Rosenberg, Seth R.; Rabbany, Sina Y.

2017-01-01

Shear stresses induced by laminar fluid flow are essential to properly recapitulate the physiological microenvironment experienced by endothelial cells (ECs). ECs respond to these stresses via mechanotransduction by modulating their phenotype and biomechanical characteristics, which can be characterized by Atomic Force Microscopy (AFM). Parallel Plate Flow Chambers (PPFCs) apply unidirectional laminar fluid flow to EC monolayers in vitro. Since ECs in sealed PPFCs are inaccessible to AFM probes, cone-and-plate viscometers (CPs) are commonly used to apply shear stress. This paper presents a comparison of the efficacies of both methods. Computational Fluid Dynamic simulation and validation testing using EC responses as a metric have indicated limitations in the use of CPs to apply laminar shear stress. Monolayers subjected to laminar fluid flow in a PPFC respond by increasing cortical stiffness, elongating, and aligning filamentous actin in the direction of fluid flow to a greater extent than CP devices. Limitations using CP devices to provide laminar flow across an EC monolayer suggest they are better suited when studying EC response for disturbed flow conditions. PPFC platforms allow for exposure of ECs to laminar fluid flow conditions, recapitulating cellular biomechanical behaviors, whereas CP platforms allow for mechanical characterization of ECs under secondary flow. PMID:28989541

Space-time correlations of fluctuating velocities in turbulent shear flows

NASA Astrophysics Data System (ADS)

Zhao, Xin; He, Guo-Wei

2009-04-01

Space-time correlations or Eulerian two-point two-time correlations of fluctuating velocities are analytically and numerically investigated in turbulent shear flows. An elliptic model for the space-time correlations in the inertial range is developed from the similarity assumptions on the isocorrelation contours: they share a uniform preference direction and a constant aspect ratio. The similarity assumptions are justified using the Kolmogorov similarity hypotheses and verified using the direct numerical simulation (DNS) of turbulent channel flows. The model relates the space-time correlations to the space correlations via the convection and sweeping characteristic velocities. The analytical expressions for the convection and sweeping velocities are derived from the Navier-Stokes equations for homogeneous turbulent shear flows, where the convection velocity is represented by the mean velocity and the sweeping velocity is the sum of the random sweeping velocity and the shear-induced velocity. This suggests that unlike Taylor’s model where the convection velocity is dominating and Kraichnan and Tennekes’ model where the random sweeping velocity is dominating, the decorrelation time scales of the space-time correlations in turbulent shear flows are determined by the convection velocity, the random sweeping velocity, and the shear-induced velocity. This model predicts a universal form of the space-time correlations with the two characteristic velocities. The DNS of turbulent channel flows supports the prediction: the correlation functions exhibit a fair good collapse, when plotted against the normalized space and time separations defined by the elliptic model.

A study of the rheology and micro-structure of dumbbells in shear geometries

NASA Astrophysics Data System (ADS)

Mandal, Sandip; Khakhar, D. V.

2018-01-01

We study the flow of frictional, inelastic dumbbells made of two fused spheres of different aspect ratios down a rough inclined plane and in a simple shear cell, using discrete element simulations. At a fixed inclination angle, the mean velocity decreases, and the volume fraction increases significantly with increasing aspect ratio in the chute flow. At a fixed solid fraction, the shear stress and pressure decrease significantly with increasing aspect ratio in the shear cell flow. The micro-structure of the flow is characterized. The translational diffusion coefficient in the normal direction to the flow is found to scale as Dy y=b γ ˙ d2, independent of aspect ratio, where b is a constant, γ ˙ is the shear rate, and d is the diameter of the constituent spheres of the dumbbells. The effective friction coefficient (μ, the ratio of shear stress to pressure) increases by 30%-35% on increasing the aspect ratio λ, from 1.0 to 1.7, for a fixed inertial number I. The volume fraction (ϕ) also increases significantly with increasing aspect ratio, especially at high inertial numbers. The effective friction coefficient and volume fraction are found to follow simple scalings of the form μ = μ(I, λ) and ϕ = ϕ(I, λ) for all the data from both systems, and the results are in reasonable agreement with kinetic theory predictions at low I. The computational results are in reasonable agreement with the experimental data for flow in a rotating cylinder.

A Rotary Flow Channel for Shear Stress Sensor Calibration

NASA Technical Reports Server (NTRS)

Zuckerwar, Allan J.; Scott, Michael A.

2004-01-01

A proposed shear sensor calibrator consists of a rotating wheel with the sensor mounted tangential to the rim and positioned in close proximity to the rim. The shear stress generated by the flow at the sensor position is simply tau(sub omega) = (mu)r(omega)/h, where mu is the viscosity of the ambient gas, r the wheel radius, omega the angular velocity of the wheel, and h the width of the gap between the wheel rim and the sensor. With numerical values of mu = 31 (mu)Pa s (neon at room temperature), r = 0.5 m, omega = 754 /s (7200 rpm), and h = 50.8 m, a shear stress of tau(sub omega) = 231 Pa can be generated. An analysis based on one-dimensional flow, with the flow velocity having only an angular component as a function of the axial and radial coordinates, yields corrections to the above simple formula for the curvature of the wheel, flatness of the sensor, and finite width of the wheel. It is assumed that the sensor mount contains a trough (sidewalls) to render a velocity release boundary condition at the edges of the rim. The Taylor number under maximum flow conditions is found to be 62.3, sufficiently low to obviate flow instability. The fact that the parameters entering into the evaluation of the shear stress can be measured to high accuracy with well-defined uncertainties makes the proposed calibrator suitable for a physical standard for shear stress calibration.

Developing Structure-Property Relationships in Branched Wormlike Micelles via Advanced Rheological and Neutron Scattering Techniques

NASA Astrophysics Data System (ADS)

Calabrese, Michelle A.

Surfactant wormlike micelles (WLMs) are of particular scientific interest due to their ability to branch, break, and reform under shear, which can lead to shear banding flow instabilities. The tunable self-assembly of WLMs makes them ubiquitous in applications ranging from consumer products to energy recovery fluids. Altering the topology of WLMs by inducing branching provides a microstructural pathway to design and optimize the flow properties for such targeted applications. The goal of this thesis is to understand the role of micellar branching on the resulting equilibrium and non-equilibrium properties, while advancing instrumentation and analysis methods in rheology and neutron scattering. The degree of branching in the mixed cationic/anionic surfactant solutions is controlled by the addition of sodium tosylate. The equilibrium properties are characterized via small angle neutron scattering (SANS), linear viscoelastic rheology, neutron spin echo, and dynamic light scattering. Combining rheology with spatiotemporally-resolved SANS enables unambiguous identification of non-equilibrium rheological and scattering signatures of branching and shear banding. The nonlinear WLM response is characterized via flow-SANS under steady shear, shear startup, and large amplitude oscillatory shear. New methods of time-resolved data analysis are developed, which improve experimental resolution by several-fold. Shear-induced orientation is a complex function of branching level, radial position, and deformation type. The structural mechanisms behind shear band formation are elucidated for steady and dynamic flows, which depend on branching level. Shear banding disappears at high branching levels for all deformation types. These responses are used to validate constitutive modeling predictions of dynamic shear banding for the first time. Finally, quantitative metrics to predict shear banding from rheology or flow-induced orientation are developed. Together, advanced rheological and neutron techniques provide a platform for creating structure-property relationships that predict flow and structural phenomena in WLMs and other soft materials. These methods have enabled characteristic differences in linear versus branched WLMs to be determined. This research is part of a broader effort to characterize branching in polymers and self-assembled systems, and may aid in the formulation of WLMs for specific applications. Finally, this work provides a basis for testing and developing microstructure-based constitutive equations that incorporate micellar breakage and branching.

Temporal gradients in shear stimulate osteoblastic proliferation via ERK1/2 and retinoblastoma protein

NASA Technical Reports Server (NTRS)

Jiang, Guang-Liang; White, Charles R.; Stevens, Hazel Y.; Frangos, John A.

2002-01-01

Bone cells are subject to interstitial fluid flow (IFF) driven by venous pressure and mechanical loading. Rapid dynamic changes in mechanical loading cause transient gradients in IFF. The effects of pulsatile flow (temporal gradients in fluid shear) on rat UMR106 cells and rat primary osteoblastic cells were studied. Pulsatile flow induced a 95% increase in S-phase UMR106 cells compared with static controls. In contrast, ramped steady flow stimulated only a 3% increase. Similar patterns of S-phase induction were also observed in rat primary osteoblastic cells. Pulsatile flow significantly increased relative UMR106 cell number by 37 and 62% at 1.5 and 24 h, respectively. Pulsatile flow also significantly increased extracellular signal-regulated kinase (ERK1/2) phosphorylation by 418%, whereas ramped steady flow reduced ERK1/2 activation to 17% of control. Correspondingly, retinoblastoma protein was significantly phosphorylated by pulsatile fluid flow. Inhibition of mitogen-activated protein (MAP)/ERK kinase (MEK)1/2 by U0126 (a specific MEK1/2 inhibitor) reduced shear-induced ERK1/2 phosphorylation and cell proliferation. These findings suggest that temporal gradients in fluid shear stress are potent stimuli of bone cell proliferation.

Investigation of Wall Shear Stress Behavior for Rough Surfaces with Blowing

NASA Astrophysics Data System (ADS)

Helvey, Jacob; Borchetta, Colby; Miller, Mark; Martin, Alexandre; Bailey, Sean

2014-11-01

We present an experimental study conducted in a turbulent channel flow wind tunnel to determine the modifications made to the turbulent flow over rough surfaces with flow injection through the surfaces. Hot-wire profile results from a quasi-two-dimensional, sinusoidally-rough surface indicate that the effects of roughness are enhanced by momentum injection through the surface. In particular, the wall shear stress was found to show behavior consistent with increased roughness height when surface blowing was increased. This observed behavior contradicts previously reported results for regular three-dimensional roughness which show a decrease in wall shear stress with additional blowing. It is unclear whether this discrepancy is due to differences in the roughness geometry under consideration or the use of the Clauser fit to estimate wall shear stress. Additional PIV experiments are being conducted for a three-dimensional fibrous surface to obtain Reynolds shear stress profiles. These results provide an additional method for estimation of wall-shear stress and thus allow verification of the use of the Clauser chart approach for flows with momentum injection through the surface. This research is supported by NASA Kentucky EPSCoR Award NNX10AV39A, and NASA RA Award NNX13AN04A.

S-shaped flow curves of shear thickening suspensions: direct observation of frictional rheology.

PubMed

Pan, Zhongcheng; de Cagny, Henri; Weber, Bart; Bonn, Daniel

2015-09-01

We study the rheological behavior of concentrated granular suspensions of simple spherical particles. Under controlled stress, the system exhibits an S-shaped flow curve (stress vs shear rate) with a negative slope in between the low-viscosity Newtonian regime and the shear thickened regime. Under controlled shear rate, a discontinuous transition between the two states is observed. Stress visualization experiments with a fluorescent probe suggest that friction is at the origin of shear thickening. Stress visualization shows that the stress in the system remains homogeneous (no shear banding) if a stress is imposed that is intermediate between the high- and low-stress branches. The S-shaped shear thickening is then due to the discontinuous formation of a frictional force network between particles upon increasing the stress.

Hydraulic properties of 3D rough-walled fractures during shearing: An experimental study

NASA Astrophysics Data System (ADS)

Yin, Qian; Ma, Guowei; Jing, Hongwen; Wang, Huidong; Su, Haijian; Wang, Yingchao; Liu, Richeng

2017-12-01

This study experimentally analyzed the influence of shear processes on nonlinear flow behavior through 3D rough-walled rock fractures. A high-precision apparatus was developed to perform stress-dependent fluid flow tests of fractured rocks. Then, water flow tests on rough-walled fractures with different mechanical displacements were conducted. At each shear level, the hydraulic pressure ranged from 0 to 0.6 MPa, and the normal load varied from 7 to 35 kN. The results show that (i) the relationship between the volumetric flow rate and hydraulic gradient of rough-walled fractures can be well fit using Forchheimer's law. Notably, both the linear and nonlinear coefficients in Forchheimer's law decrease during shearing; (ii) a sixth-order polynomial function is used to evaluate the transmissivity based on the Reynolds number of fractures during shearing. The transmissivity exhibits a decreasing trend as the Reynolds number increases and an increasing trend as the shear displacement increases; (iii) the critical hydraulic gradient, critical Reynolds number and equivalent hydraulic aperture of the rock fractures all increase as the shear displacement increases. When the shear displacement varies from 0 to 15 mm, the critical hydraulic gradient ranges from 0.3 to 2.2 for a normal load of 7 kN and increases to 1.8-8.6 for a normal load of 35 kN; and (iv) the Forchheimer law results are evaluated by plotting the normalized transmissivity of the fractures during shearing against the Reynolds number. An increase in the normal load shifts the fitted curves downward. Additionally, the Forchheimer coefficient β decreases with the shear displacement but increases with the applied normal load.

Instability-induced ordering, universal unfolding and the role of gravity in granular Couette flow

NASA Astrophysics Data System (ADS)

Alam, Meheboob; Arakeri, V. H.; Nott, P. R.; Goddard, J. D.; Herrmann, H. J.

2005-01-01

Linear stability theory and bifurcation analysis are used to investigate the role of gravity in shear-band formation in granular Couette flow, considering a kinetic-theory rheological model. We show that the only possible state, at low shear rates, corresponds to a "plug" near the bottom wall, in which the particles are densely packed and the shear rate is close to zero, and a uniformly sheared dilute region above it. The origin of such plugged states is shown to be tied to the spontaneous symmetry-breaking instabilities of the gravity-free uniform shear flow, leading to the formation of ordered bands of alternating dilute and dense regions in the transverse direction, via an infinite hierarchy of pitchfork bifurcations. Gravity plays the role of an "imperfection", thus destroying the "perfect" bifurcation structure of uniform shear. The present bifurcation problem admits universal unfolding of pitchfork bifurcations which subsequently leads to the formation of a sequence of a countably infinite number of "isolas", with the solution structures being a modulated version of their gravity-free counterpart. While the solution with a plug near the bottom wall looks remarkably similar to the shear-banding phenomenon in dense slow granular Couette flows, a "floating" plug near the top wall is also a solution of these equations at high shear rates. A two-dimensional linear stability analysis suggests that these floating plugged states are unstable to long-wave travelling disturbances.The unique solution having a bottom plug can also be unstable to long waves, but remains stable at sufficiently low shear rates. The implications and realizability of the present results are discussed in the light of shear-cell experiments under "microgravity" conditions.

The Magnetohydrodynamic Kelvin-Helmholtz Instability. III. The Role of Sheared Magnetic Field in Planar Flows

NASA Astrophysics Data System (ADS)

Jeong, Hyunju; Ryu, Dongsu; Jones, T. W.; Frank, Adam

2000-01-01

We have carried out simulations of the nonlinear evolution of the magnetohydrodynamic (MHD) Kelvin-Helmholtz (KH) instability for compressible fluids in 2.5 dimensions, extending our previous work by Frank et al. and Jones et al. In the present work we have simulated flows in the x-y plane in which a ``sheared'' magnetic field of uniform strength smoothly rotates across a thin velocity shear layer from the z-direction to the x-direction, aligned with the flow field. The sonic Mach number of the velocity transition is unity. Such flows containing a uniform field in the x-direction are linearly stable if the magnetic field strength is great enough that the Alfvénic Mach number MA=U0/cA<2. That limit does not apply directly to sheared magnetic fields, however, since the z-field component has almost no influence on the linear stability. Thus, if the magnetic shear layer is contained within the velocity shear layer, the KH instability may still grow, even when the field strength is quite large. So, here we consider a wide range of sheared field strengths covering Alfvénic Mach numbers, MA=142.9 to 2. We focus on dynamical evolution of fluid features, kinetic energy dissipation, and mixing of the fluid between the two layers, considering their dependence on magnetic field strength for this geometry. There are a number of differences from our earlier simulations with uniform magnetic fields in the x-y plane. For the latter, simpler case we found a clear sequence of behaviors with increasing field strength ranging from nearly hydrodynamic flows in which the instability evolves to an almost steady cat's eye vortex with enhanced dissipation, to flows in which the magnetic field disrupts the cat's eye once it forms, to, finally, flows that evolve very little before field-line stretching stabilizes the velocity shear layer. The introduction of magnetic shear can allow a cat's eye-like vortex to form, even when the field is stronger than the nominal linear instability limit given above. For strong fields that vortex is asymmetric with respect to the preliminary shear layer, however, so the subsequent dissipation is enhanced over the uniform field cases of comparable field strength. In fact, so long as the magnetic field achieves some level of dynamical importance during an eddy turnover time, the asymmetries introduced through the magnetic shear will increase flow complexity and, with that, dissipation and mixing. The degree of the fluid mixing between the two layers is strongly influenced by the magnetic field strength. Mixing of the fluid is most effective when the vortex is disrupted by magnetic tension during transient reconnection, through local chaotic behavior that follows.

E  ×  B flow shear drive of the linear low-n modes of EHO in the QH-mode regime

NASA Astrophysics Data System (ADS)

Xu, G. S.; Wan, B. N.; Wang, Y. F.; Wu, X. Q.; Chen, Xi; Peng, Y.-K. Martin; Guo, H. Y.; Burrell, K. H.; Garofalo, A. M.; Osborne, T. H.; Groebner, R. J.; Wang, H. Q.; Chen, R.; Yan, N.; Wang, L.; Ding, S. Y.; Shao, L. M.; Hu, G. H.; Li, Y. L.; Lan, H.; Yang, Q. Q.; Chen, L.; Ye, Y.; Xu, J. C.; Li, J.

2017-08-01

A new model for the edge harmonic oscillations (EHOs) in the quiescent H-mode regime has been developed, which successfully reproduces the recent observations in the DIII-D tokamak. In particular, at high E  ×  B flow shear only a few low-n kink modes remain unstable at the plasma edge, consistent with the EHO behavior, while at low E  ×  B flow shear, the unstable mode spectrum is significantly broadened, consistent with the low-n broadband electromagnetic turbulence behavior. The model is based on a new mechanism for destabilizing low-n kink/peeling modes by the E  ×  B flow shear, which underlies the EHOs, separately from the previously found Kelvin-Helmholtz drive. We find that the differential advection of mode vorticity by sheared E  ×  B flows modifies the 2D pattern of mode electrostatic potential perpendicular to the magnetic field lines, which in turn causes a radial expansion of the mode structure, an increase of field line bending away from the mode rational surface, and a reduction of inertial stabilization. This enhances the kink drive as the parallel wavenumber increases significantly away from the rational surface at the plasma edge where the magnetic shear is also strong. This destabilization is also shown to be independent of the sign of the flow shear, as observed experimentally, and has not been taken into account in previous pedestal linear stability analyses. Verification of the veracity of this EHO mechanism will require analysis of the nonlinear evolution of low-n kink/peeling modes so destabilized in the linear regime.

Investigation of Flow Structures Downstream of SAPIEN 3, CoreValve, and PERIMOUNT Magna Using Particle Image Velocimetry

NASA Astrophysics Data System (ADS)

Barakat, Mohammed; Lengsfeld, Corinne; Dvir, Danny; Azadani, Ali

2017-11-01

Transcatheter aortic valves provide superior systolic hemodynamic performance in terms of valvular pressure gradient and effective orifice area compared with equivalent size surgical bioprostheses. However, in depth investigation of the flow field structures is of interest to examine the flow field characteristics and provide experimental evidence necessary for validation of computational models. The goal of this study was to compare flow field characteristics of the three most commonly used transcatheter and surgical valves using phase-locked particle image velocimetry (PIV). 26mm SAPIEN 3, 26mm CoreValve, and 25mm PERIMOUNT Magna were examined in a pulse duplicator with input parameters matching ISO-5840. A 2D PIV system was used to obtain the velocity fields. Flow velocity and shear stress were obtained during the entire cardiac cycle. In-vitro testing showed that mean gradient was lowest for SAPIEN 3, followed by CoreValve and PERIMOUNT Magna. In all the valves, the peak jet velocity and maximum viscous shear stress were 2 m/s and 2 MPa, respectively. In conclusion, PIV was used to investigate flow field downstream of the three bioprostheses. Viscous shear stress was low and consequently shear-induced thrombotic trauma or shear-induced damage to red blood cells is unlikely.

Shear and shearless Lagrangian structures in compound channels

NASA Astrophysics Data System (ADS)

Enrile, F.; Besio, G.; Stocchino, A.

2018-03-01

Transport processes in a physical model of a natural stream with a composite cross-section (compound channel) are investigated by means of a Lagrangian analysis based on nonlinear dynamical system theory. Two-dimensional free surface Eulerian experimental velocity fields of a uniform flow in a compound channel form the basis for the identification of the so-called Lagrangian Coherent Structures. Lagrangian structures are recognized as the key features that govern particle trajectories. We seek for two particular class of Lagrangian structures: Shear and shearless structures. The former are generated whenever the shear dominates the flow whereas the latter behave as jet-cores. These two type of structures are detected as ridges and trenches of the Finite-Time Lyapunov Exponents fields, respectively. Besides, shearlines computed applying the geodesic theory of transport barriers mark Shear Lagrangian Coherent Structures. So far, the detection of these structures in real experimental flows has not been deeply investigated. Indeed, the present results obtained in a wide range of the controlling parameters clearly show a different behaviour depending on the shallowness of the flow. Shear and Shearless Lagrangian Structures detected from laboratory experiments clearly appear as the flow develops in shallow conditions. The presence of these Lagrangian Structures tends to fade in deep flow conditions.

Effects of capillary heterogeneity on vapor-liquid counterflow in porous media

NASA Astrophysics Data System (ADS)

Stubos, A. K.; Satik, C.; Yortsos, Y. C.

1992-06-01

Based on a continuum description, the effect of capillary heterogeneity, induced by variation in permeability, on the steady state, countercurrent, vapor-liquid flow in porous media is analyzed. It is shown that the heterogeneity acts as a body force that may enhance or diminish gravity effects on heat pipes. Selection rules that determine the steady states reached in homogeneous, gravity-driven heat pipes are also formulated. It is shown that the 'infinite' two-phase zone may terminate by a substantial change in the permeability somewhere in the medium. The two possible sequences, liquid-liquid dominated-dry, or liquid-vapor dominated-dry find applications in geothermal systems. Finally, it is shown that although weak heterogeneity affects only gravity controlled flows, stronger variations in permeability can give rise to significant capillary effects.

Ignition dynamics of a laminar diffusion flame in the field of a vortex embedded in a shear flow

NASA Technical Reports Server (NTRS)

Macaraeg, Michele G.; Jackson, T. L.; Hussaini, M. Y.

1994-01-01

The role of streamwise-spanwise vorticity interactions that occur in turbulent shear flows on flame/vortex interactions is examined by means of asymptotic analysis and numerical simulation in the limit of small Mach number. An idealized model is employed to describe the interaction process. The model consists of a one-step, irreversible Arrhenius reaction between initially unmixed species occupying adjacent half-planes which are then allowed to mix and react in the presence of a streamwise vortex embedded in a shear flow. It is found that the interaction of the streamwise vortex with shear gives rise to small-scale velocity oscillations which increase in magnitude with shear strength. These oscillations give rise to regions of strong temperature gradients via viscous heating, which can lead to multiple ignition points and substantially decrease ignition times. The evolution in time of the temperature and mass-fraction fields is followed, and emphasis is placed on the ignition time and structure as a function of vortex and shear strength.

A comparative numerical analysis of linear and nonlinear aerodynamic sound generation by vortex disturbances in homentropic constant shear flows

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hau, Jan-Niklas, E-mail: hau@fdy.tu-darmstadt.de; Oberlack, Martin; GSC CE, Technische Universität Darmstadt, Dolivostraße 15, 64293 Darmstadt

2015-12-15

Aerodynamic sound generation in shear flows is investigated in the light of the breakthrough in hydrodynamics stability theory in the 1990s, where generic phenomena of non-normal shear flow systems were understood. By applying the thereby emerged short-time/non-modal approach, the sole linear mechanism of wave generation by vortices in shear flows was captured [G. D. Chagelishvili, A. Tevzadze, G. Bodo, and S. S. Moiseev, “Linear mechanism of wave emergence from vortices in smooth shear flows,” Phys. Rev. Lett. 79, 3178-3181 (1997); B. F. Farrell and P. J. Ioannou, “Transient and asymptotic growth of two-dimensional perturbations in viscous compressible shear flow,” Phys.more » Fluids 12, 3021-3028 (2000); N. A. Bakas, “Mechanism underlying transient growth of planar perturbations in unbounded compressible shear flow,” J. Fluid Mech. 639, 479-507 (2009); and G. Favraud and V. Pagneux, “Superadiabatic evolution of acoustic and vorticity perturbations in Couette flow,” Phys. Rev. E 89, 033012 (2014)]. Its source is the non-normality induced linear mode-coupling, which becomes efficient at moderate Mach numbers that is defined for each perturbation harmonic as the ratio of the shear rate to its characteristic frequency. Based on the results by the non-modal approach, we investigate a two-dimensional homentropic constant shear flow and focus on the dynamical characteristics in the wavenumber plane. This allows to separate from each other the participants of the dynamical processes — vortex and wave modes — and to estimate the efficacy of the process of linear wave-generation. This process is analyzed and visualized on the example of a packet of vortex modes, localized in both, spectral and physical, planes. Further, by employing direct numerical simulations, the wave generation by chaotically distributed vortex modes is analyzed and the involved linear and nonlinear processes are identified. The generated acoustic field is anisotropic in the wavenumber plane, which results in highly directional linear sound radiation, whereas the nonlinearly generated waves are almost omni-directional. As part of this analysis, we compare the effectiveness of the linear and nonlinear mechanisms of wave generation within the range of validity of the rapid distortion theory and show the dominance of the linear aerodynamic sound generation. Finally, topological differences between the linear source term of the acoustic analogy equation and of the anisotropic non-normality induced linear mechanism of wave generation are found.« less

Morphology-flow interactions lead to stage-selective vertical transport of larval sand dollars in shear flow.

PubMed

Clay, T W; Grünbaum, D

2010-04-01

Many larvae and other plankton have complex and variable morphologies of unknown functional significance. We experimentally and theoretically investigated the functional consequences of the complex morphologies of larval sand dollars, Dendraster excentricus (Eschscholtz), for hydrodynamic interactions between swimming and turbulent water motion. Vertical shearing flows (horizontal gradients of vertical flow) tilt organisms with simple geometries (e.g. spheres, ellipsoids), causing these organisms to move horizontally towards downwelling water and compromising their abilities to swim upwards. A biomechanical model of corresponding hydrodynamic interactions between turbulence-induced shear and the morphologically complex four-, six- and eight-armed stages of sand dollar larvae suggests that the movements of larval morphologies differ quantitatively and qualitatively across stages and shear intensities: at shear levels typical of calm conditions in estuarine and coastal environments, all modeled larval stages moved upward. However, at higher shears, modeled four- and eight-armed larvae moved towards downwelling, whereas six-armed larvae moved towards upwelling. We also experimentally quantified larval movement by tracking larvae swimming in low-intensity shear while simultaneously mapping the surrounding flow fields. Four- and eight-armed larvae moved into downwelling water, but six-armed larvae did not. Both the model and experiments suggest that stage-dependent changes to larval morphology lead to differences in larval movement: four- and eight-armed stages are more prone than the six-armed stage to moving into downwelling water. Our results suggest a mechanism by which differences can arise in the vertical distribution among larval stages. The ability to mitigate or exploit hydrodynamic interactions with shear is a functional consequence that potentially shapes larval evolution and development.

Modeling the Inhomogeneous Response of Steady and Transient Flows of Entangled Micellar Solutions

NASA Astrophysics Data System (ADS)

McKinley, Gareth

2008-03-01

Surfactant molecules can self-assemble in solution into long flexible structures known as wormlike micelles. These structures entangle, forming a viscoelastic network similar to those in entangled polymer melts and solutions. However, in contrast to `inert' polymeric networks, wormlike micelles continuously break and reform leading to an additional relaxation mechanism and the name `living polymers'. Observations in both classes of entangled fluids have shown that steady and transient shearing flows of these solutions exhibit spatial inhomogeneities such as `shear-bands' at sufficiently large applied strains. In the present work, we investigate the dynamical response of a class of two-species elastic network models which can capture, in a self-consistent manner, the creation and destruction of elastically-active network segments, as well as diffusive coupling between the microstructural conformations and the local state of stress in regions with large spatial gradients of local deformation. These models incorporate a discrete version of the micellar breakage and reforming dynamics originally proposed by Cates and capture, at least qualitatively, non-affine tube deformation and chain disentanglement. The `flow curves' of stress and apparent shear rate resulting from an assumption of homogeneous deformation is non-monotonic and linear stability analysis shows that the region of non-monotonic response is unstable. Calculation of the full inhomogeneous flow field results in localized shear bands that grow linearly in extent across the gap as the apparent shear rate increases. Time-dependent calculations in step strain, large amplitude oscillatory shear (LAOS) and in start up of steady shear flow show that the velocity profile in the gap and the total stress measured at the bounding surfaces are coupled and evolve in a complex non-monotonic manner as the shear bands develop and propagate.

Understanding roles of E  ×  B flow and magnetic shear on the formation of internal and edge transport barriers using two-field bifurcation concept

NASA Astrophysics Data System (ADS)

Chatthong, B.; Onjun, T.

2016-01-01

A set of heat and particle transport equations with the inclusion of E  ×  B flow and magnetic shear is used to understand the formation and behaviors of edge transport barriers (ETBs) and internal transport barriers (ITBs) in tokamak plasmas based on two-field bifurcation concept. A simple model that can describe the E  ×  B flow shear and magnetic shear effect in tokamak plasma is used for anomalous transport suppression with the effect of bootstrap current included. Consequently, conditions and formations of ETB and ITB can be visualized and studied. It can be seen that the ETB formation depends sensitively on the E  ×  B flow shear suppression with small dependence on the magnetic shear suppression. However, the ITB formation depends sensitively on the magnetic shear suppression with a small dependence on the E  ×  B flow shear suppression. Once the H-mode is achieved, the s-curve bifurcation diagram is modified due to an increase of bootstrap current at the plasma edge, resulting in reductions of both L-H and H-L transition thresholds with stronger hysteresis effects. It is also found that both ITB and ETB widths appear to be governed by heat or particle sources and the location of the current peaking. In addition, at a marginal flux just below the L-H threshold, a small perturbation in terms of heat or density fluctuation can result in a transition, which can remain after the perturbation is removed due to the hysteresis effect.

Platelet-free shear flow assay facilitates analysis of shear-dependent functions of VWF and ADAMTS13.

PubMed

Kraus, Emma; Kraus, Kristina; Obser, Tobias; Oyen, Florian; Klemm, Ulrike; Schneppenheim, Reinhard; Brehm, Maria A

2014-12-01

The multimeric form of von Willebrand factor (VWF), is the largest soluble protein in mammals and exhibits a multidomain structure resulting in multiple functions. Upon agonist stimulation endothelial cells secrete VWF multimers from Weibel-Palade bodies into the blood stream where VWF plays an essential role in platelet-dependent primary hemostasis. Elongation of VWF strings on the cells' surface leads to accessibility of VWF binding sites for proteins, such as platelet membrane glycoprotein Ib. The prothrombotic strings are size-regulated by the metalloprotease ADAMTS13 by shear force-activated proteolytic cleavage. VWF string formation was induced by histamine stimulation of HUVEC cells under unidirectional shear flow and VWF strings were detected employing the VWF binding peptide of platelet glycoprotein Ib coupled to latex beads. VWF strings were then used as substrate for kinetic studies of recombinant and plasma ADAMTS13. To investigate specific aspects of the shear-dependent functions of VWF and ADAMTS13, we developed a shear flow assay that allows observation of VWF string formation and their degradation by ADAMTS13 without the need for isolated platelets. Our assay specifically detects VWF strings, can be coupled with fluorescent applications and allows semi-automated, quantitative assessment of recombinant and plasma ADAMTS13 activity. Our assay may serve as a valuable research tool to investigate the biochemical characteristics of VWF and ADAMTS13 under shear flow and could complement diagnostics of von Willebrand Disease and Thrombotic Thrombocytopenic Purpura as it allows detection of shear flow-dependent dysfunction of VWD-associated VWF mutants as well as TTP-associated ADAMTS13 mutants. Copyright © 2014 Elsevier Ltd. All rights reserved.

ITG modes in the presence of inhomogeneous field-aligned flow

NASA Astrophysics Data System (ADS)

Sen, S.; McCarthy, D. R.; Lontano, M.; Lazzaro, E.; Honary, F.

2010-02-01

In a recent paper, Varischetti et al. (Plasma Phys. Contr. F. 2008, 50, 105008-1-15) have found that in a slab geometry the effect of the flow shear in the field-aligned parallel flow on the linear mode stability of the ion temperature gradient (ITG)-driven modes is not very prominent. They found that the flow shear also has a negligible effect on the mode characteristics. The work in this paper shows that the inclusion of flow curvature in the field-aligned flow can have a considerable effect on the mode stability; it can also change the mode structure so as to effect the mixing length transport in the core region of a fusion device. Flow shear, on the other hand, has indeed an insignificant role in the mode stability and mode structure. Inhomogeneous field-aligned flow should therefore still be considered for a viable candidate in controlling the ITG mode stability and mode structure.

Jammed Clusters and Non-locality in Dense Granular Flows

NASA Astrophysics Data System (ADS)

Kharel, Prashidha; Rognon, Pierre

We investigate the micro-mechanisms underpinning dense granular flow behaviour from a series of DEM simulations of pure shear flows of dry grains. We observe the development of transient clusters of jammed particles within the flow. Typical size of such clusters is found to scale with the inertial number with a power law that is similar to the scaling of shear-rate profile relaxation lengths observed previously. Based on the simple argument that transient clusters of size l exist in the dense flow regime, the formulation of steady state condition for non-homogeneous shear flow results in a general non-local relation, which is similar in form to the non-local relation conjectured for soft glassy flows. These findings suggest the formation of jammed clusters to be the key micro-mechanism underpinning non-local behaviour in dense granular flows. Particles and Grains Laboratory, School of Civil Engineering, The University of Sydney, Sydney, NSW 2006, Australia.

Measurement of velocity distribution and turbulence in a special wind tunnel using a laser Doppler velocimeter

NASA Astrophysics Data System (ADS)

Mueller, J.; Petersen, J. C.; Pilz, E.; Wiegand, H.

1981-06-01

The flow behavior in a jet mixing visualization chamber for turbulent fuel spray mixing with air under compression, e.g., at top dead center in diesel engines, was investigated with a laser Doppler velocimeter. The measurements were performed in two cuts in the profile perpendicular to the flow direction. The range of flow conditions in the measuring chamber was tested. The measurements were conducted with and without turbulence grids and shear flow grids behind the inlet nozzle. Wire grids did not enhance the turbulence in the measuring chamber. One of the tested shear flow grids produced shear flow as expected. A turbulence grid whose design was based on experimental results, produced a turbulence degree of up to 30% over the whole measuring cross section.

Changes in blood flow due to stented parent artery expansion in an intracranial aneurysm.

PubMed

Mori, Futoshi; Ohta, Makoto; Matsuzawa, Teruo

2015-01-01

Stent placement is thought to obstruct the inflow of blood to an aneurysm. However, we introduced parent artery expansion and demonstrated that this may reduce the blood flow by the stent. In our previous study using idealized shapes, the results showed that flow reduction was greater than 22.2%, even if the expansion rate was only 6%. Furthermore, the parent artery expansion is predominantly caused by the effect of flow reduction as compared to that of flow reduction due to the obstruction of flow under stent placement. However, a realistic shape is complex and the blood flow also becomes complex flow. It is not understood whether the results of flow in the idealized shape are reflective of flow from a realistic 3D model. Therefore, we examined the effect of parent artery expansion using a realistic model. The aim is to clarify the effects of parent artery expansion on inflow rate, wall shear stress, and oscillatory shear index. We used a patient-specific geometry of a human internal carotid artery with an aneurysm. The geometry of parent artery expansion due to oversized stent constructed based on the voronoi diagram. We performed calculations in the unsteady-state situations using constructed models. The complexity of the flow in the aneurysm decreases in case of expanded parent artery. The inflow rate decreases by 33.6% immediately after parent artery expansion alone without a stent. The effect of the parent artery expansion on flow reduction is larger than that of the obstruction flow by stent placement. In addition, wall shear stress and oscillatory shear index on the aneurysm wall decrease by change in blood flow due to the parent artery expansion. The effects of the parent artery expansion in a realistic aneurysm model with different stent lengths were evaluated on the basis of a numerical simulation. Although the flow was complex, the parent artery expansion with stent reduces the inflow to the aneurysm and wall shear stress and oscillatory shear index on the aneurysm. Therefore, we suggest that changes in the blood flow because of the parent artery expansion may be identified and, sometimes, is more effective than the obstruction flow due to the stent placement.

Abdominal Aortic Hemodynamics in Intermittent Claudication Patients at Rest and During Dynamic Pedaling Exercise

PubMed Central

Cheng, Christopher P.; Taylor, Charles A.; Dalman, Ronald L.

2015-01-01

Introduction Lower extremity exercise has been shown to eliminate adverse hemodynamics conditions, such as low and oscillating blood flow and wall shear stress, in the abdominal aortas of healthy young and older adults. Methods We use cine phase-contrast magnetic resonance imaging and a custom MRI-compatible exercise cycle to quantify hemodynamic changes due to pedaling exercise in patients diagnosed with intermittent claudication. Results and Conclusions With only an average heart increase of 35±18% and exercise workload of 36±16 Watts, the patients experienced approximately 3- and 6-fold increases in blood flow, and 4- and 16-fold increases in wall shear stress at the supraceliac and infrarenal aortic locations, respectively. Also, all oscillations in flow and shear stress at rest were eliminated with exercise. Claudication patients experience 3 to 4-fold lower oscillations in flow and shear stress at rest as compared to healthy age-matched controls, likely due to reduced distal arterial compliance as a result of distal atherosclerosis. The magnitude of flow and shear oscillatory indices may be good indicators of distal arterial compliance and health, and may provide predictive power for the efficacy of focal interventions. PMID:26315797

Elastic turbulence in entangled semi-dilute DNA solutions measured with optical coherence tomography velocimetry.

PubMed

Malm, A V; Waigh, T A

2017-04-26

The flow instabilities of solutions of high molecular weight DNA in the entangled semi-dilute concentration regime were investigated using optical coherence tomography velocimetry, a technique that provides high spatial (probe volumes of 3.4 pL) and temporal resolution (sub μs) information on the flow behaviour of complex fluids in a rheometer. The velocity profiles of the opaque DNA solutions (high and low salt) were measured as a function of the distance across the gap of a parallel plate rheometer, and their evolution over time was measured. At lower DNA concentrations and low shear rates, the velocity fluctuations were well described by Gaussian functions and the velocity gradient was uniform across the rheometer gap, which is expected for Newtonian flows. As the DNA concentration and shear rate were increased there was a stable wall slip regime followed by an evolving wall slip regime, which is finally followed by the onset of elastic turbulence. Strain localization (shear banding) is observed on the boundaries of the flows at intermediate shear rates, but decreases in the high shear elastic turbulence regime, where bulk strain localization occurs. A dynamic phase diagram for non-linear flow was created to describe the different behaviours.

Variational approach to stability boundary for the Taylor-Goldstein equation

NASA Astrophysics Data System (ADS)

Hirota, Makoto; Morrison, Philip J.

2015-11-01

Linear stability of inviscid stratified shear flow is studied by developing an efficient method for finding neutral (i.e., marginally stable) solutions of the Taylor-Goldstein equation. The classical Miles-Howard criterion states that stratified shear flow is stable if the local Richardson number JR is greater than 1/4 everywhere. In this work, the case of JR > 0 everywhere is considered by assuming strictly monotonic and smooth profiles of the ambient shear flow and density. It is shown that singular neutral modes that are embedded in the continuous spectrum can be found by solving one-parameter families of self-adjoint eigenvalue problems. The unstable ranges of wavenumber are searched for accurately and efficiently by adopting this method in a numerical algorithm. Because the problems are self-adjoint, the variational method can be applied to ascertain the existence of singular neutral modes. For certain shear flow and density profiles, linear stability can be proven by showing the non-existence of a singular neutral mode. New sufficient conditions, extensions of the Rayleigh-Fjortoft stability criterion for unstratified shear flows, are derived in this manner. This work was supported by JSPS Strategic Young Researcher Overseas Visits Program for Accelerating Brain Circulation # 55053270.

Utility of Squeeze Flow in the Food Industry

NASA Astrophysics Data System (ADS)

Huang, T. A.

2008-07-01

Squeeze flow for obtaining shear viscosity on Newtonian and non-Newtonian fluids has long been established in the literature. Rotational shear flow using cone/plate, a set of parallel plates, or concentric cylinders all develop wall slip, shear fracture, or instability on food related materials such as peanut butter or mayonnaise. Viscosity data obtained using any one of the above mentioned set-ups is suspect or potentially results in significant error. They are unreliable to support or predict the textural differences perceived by consumer evaluation. RMS-800, from Rheometrics Inc., was employed to conduct the squeezing flow under constant speeds on a set of parallel plates. Viscosity data, over a broad range of shear rates, is compared between Hellmann's real (HRM) and light mayonnaise (HLM). The Consistency and shear-thinning indices, as defined in the Power-Law Model, were determined. HRM exhibits a more pronounced shear-thinning when compared to HLM yet the Consistency of HRM is significantly higher. Sensory evaluation by a trained expert panel ranked that adhesiveness and cohesiveness of HLM are significantly higher. It appears that the degree of shear thinning is one of the key rheological parameters in predicting the above mentioned difference in textural attributes. Error involved in determining viscosity from non-parallelism between two plates can be significant to affect the accuracy of the viscosity, in particular, shear-thinning index. Details are a subject for the next presentation. Nevertheless, the method is proven to be fast, rugged, simple, and reliable. It can be developed as a QC tool.

Quantification of wall shear stress in large blood vessels using Lagrangian interpolation functions with cine phase-contrast magnetic resonance imaging.

PubMed

Cheng, Christopher P; Parker, David; Taylor, Charles A

2002-09-01

Arterial wall shear stress is hypothesized to be an important factor in the localization of atherosclerosis. Current methods to compute wall shear stress from magnetic resonance imaging (MRI) data do not account for flow profiles characteristic of pulsatile flow in noncircular vessel lumens. We describe a method to quantify wall shear stress in large blood vessels by differentiating velocity interpolation functions defined using cine phase-contrast MRI data on a band of elements in the neighborhood of the vessel wall. Validation was performed with software phantoms and an in vitro flow phantom. At an image resolution corresponding to in vivo imaging data of the human abdominal aorta, time-averaged, spatially averaged wall shear stress for steady and pulsatile flow were determined to be within 16% and 23% of the analytic solution, respectively. These errors were reduced to 5% and 8% with doubling in image resolution. For the pulsatile software phantom, the oscillation in shear stress was predicted to within 5%. The mean absolute error of circumferentially resolved shear stress for the nonaxisymmetric phantom decreased from 28% to 15% with a doubling in image resolution. The irregularly shaped phantom and in vitro investigation demonstrated convergence of the calculated values with increased image resolution. We quantified the shear stress at the supraceliac and infrarenal regions of a human abdominal aorta to be 3.4 and 2.3 dyn/cm2, respectively.

Recovery of butanol by counter-current carbon dioxide fractionation with its potential application to butanol fermentation

USDA-ARS?s Scientific Manuscript database

A counter-current CO2 fractionation method was studied as a means to recover butanol (also known as 1-butanol or n-butanol) and other compounds that are typically obtained from biobutanol fermentation broth from aqueous solutions. The influence of operating parameters, such as solvent-to-feed ratio,...

Separation and characterisation of five polar herbicides using countercurrent chromatography with detection by negative ion electrospray ionisation mass spectrometry.

PubMed

Kidwell, H; Jones, J J; Games, D E

2001-01-01

Five polar herbicides were separated and characterised using high-speed analytical countercurrent chromatography (HSACCC) in conjunction with online electrospray mass spectrometry (ESI-MS). The countercurrent chromatography used a standard isocratic biphasic solvent system of hexane/ethyl acetate/methanol/water in reverse phase to effect the separation of these five environmentally important compounds. The chromatograph was coupled to a triple quadrupole mass spectrometer via a standard electrospray liquid chromatography interface that was able to give mass spectra in negative ion mode of each compound. Limits of detection are reported for this series of compounds along with representative negative ion ESI-MS data and calibrations for the separation. Copyright 2001 John Wiley & Sons, Ltd.

Expression of endothelin-1 and constitutional nitric oxide synthase messenger RNA in saphenous vein endothelial cells exposed to arterial flow shear stress.

PubMed

Zhu, Z G; Li, H H; Zhang, B R

1997-11-01

It has long been speculated that increased blood flow shear stress might be one of the major factors affecting the patency of grafted saphenous vein in coronary artery bypass operations. The underlying cellular and molecular mechanisms for so-called "shear stress damage" have not yet been well elucidated. Endothelial cells harvested from human saphenous vein were cultured in vitro and then exposed to a high arterial level flow shear stress in the parallel flow chamber. The expression levels of endothelin-1 and constitutional nitric oxide synthase by the endothelial cells were evaluated semiquantitatively at the gene transcription (messenger RNA) level using reverse transcription polymerase chain reaction. After 7 hours of exposure to arterial level shear stress, the expression of constitutional nitric oxide synthase messenger RNA by saphenous vein endothelial cells was significantly reduced, whereas the expression of endothelin-1 messenger RNA was substantially increased. These changes were more predominant at 24 hours. Arterial level flow shear stress could cause important changes in the gene transcription level in saphenous vein endothelial cells within a short period of time. The functional alterations of saphenous vein endothelial cells, as manifested by the increased expression of endothelin-1 and decreased expression of nitric oxide synthase messenger RNA, might play a crucial role in the vein graft remodeling process.

Deformation of a Capsule in a Power-Law Shear Flow

PubMed Central

2016-01-01

An immersed boundary-lattice Boltzmann method is developed for fluid-structure interactions involving non-Newtonian fluids (e.g., power-law fluid). In this method, the flexible structure (e.g., capsule) dynamics and the fluid dynamics are coupled by using the immersed boundary method. The incompressible viscous power-law fluid motion is obtained by solving the lattice Boltzmann equation. The non-Newtonian rheology is achieved by using a shear rate-dependant relaxation time in the lattice Boltzmann method. The non-Newtonian flow solver is then validated by considering a power-law flow in a straight channel which is one of the benchmark problems to validate an in-house solver. The numerical results present a good agreement with the analytical solutions for various values of power-law index. Finally, we apply this method to study the deformation of a capsule in a power-law shear flow by varying the Reynolds number from 0.025 to 0.1, dimensionless shear rate from 0.004 to 0.1, and power-law index from 0.2 to 1.8. It is found that the deformation of the capsule increases with the power-law index for different Reynolds numbers and nondimensional shear rates. In addition, the Reynolds number does not have significant effect on the capsule deformation in the flow regime considered. Moreover, the power-law index effect is stronger for larger dimensionless shear rate compared to smaller values. PMID:27840656

An inkjet-printed microfluidic device for liquid-liquid extraction.

PubMed

Watanabe, Masashi

2011-04-07

A microfluidic device for liquid-liquid extraction was quickly produced using an office inkjet printer. An advantage of this method is that normal end users, who are not familiar with microfabrication, can produce their original microfluidic devices by themselves. In this method, the printer draws a line on a hydrophobic and oil repellent surface using hydrophilic ink. This line directs a fluid, such as water or xylene, to form a microchannel along the printed line. Using such channels, liquid-liquid extraction was successfully performed under concurrent and countercurrent flow conditions. © The Royal Society of Chemistry 2011

Effects of bulk and free surface shear flows on amyloid fibril formation

NASA Astrophysics Data System (ADS)

Posada, David; Sorci, Mirco; Belfort, Georges; Hirsa, Amir

2008-11-01

Amyloid diseases such as Alzheimer's and Huntington's, among others, are characterized by the conversion of monomers to oligomers (precursors) and then to amyloid fibrils. Besides factors such as concentration, pH, and ionic strength, evidence exists that shearing flow strongly influences amyloid formation in vitro. Also, during fibrillation in the presence of either gas or solid surfaces, both the polarity and roughness of the surfaces play a significant role in the kinetics of the fibrillation process. By studying the nucleation and growth of a model system (insulin fibrils) in a well-defined flow field, we can identify the flow and interfacial conditions that impact protein aggregation kinetics. The present flow system consists of an annular region, bounded by stationary inner and outer cylinders and driven by rotation of the floor, with either a hydrophobic (air) or hydrophilic (solid) interface. We show both the combined and separated effects of shear and interfacial hydrophobicity on the fibrillation process, and the use of interfacial shear viscosity as a parameter for quantifying the oligomerization process.

Molecular cloud formation in high-shear, magnetized colliding flows

NASA Astrophysics Data System (ADS)

Fogerty, E.; Frank, A.; Heitsch, F.; Carroll-Nellenback, J.; Haig, C.; Adams, M.

2016-08-01

The colliding flows (CF) model is a well-supported mechanism for generating molecular clouds. However, to-date most CF simulations have focused on the formation of clouds in the normal-shock layer between head-on colliding flows. We performed simulations of magnetized colliding flows that instead meet at an oblique-shock layer. Oblique shocks generate shear in the post-shock environment, and this shear creates inhospitable environments for star formation. As the degree of shear increases (I.e. the obliquity of the shock increases), we find that it takes longer for sink particles to form, they form in lower numbers, and they tend to be less massive. With regard to magnetic fields, we find that even a weak field stalls gravitational collapse within forming clouds. Additionally, an initially oblique collision interface tends to reorient over time in the presence of a magnetic field, so that it becomes normal to the oncoming flows. This was demonstrated by our most oblique shock interface, which became fully normal by the end of the simulation.

Gas flow-field induced director alignment in polymer dispersed liquid crystal microdroplets deposited on a glass substrate

NASA Technical Reports Server (NTRS)

Parmar, D. S.; Singh, J. J.

1993-01-01

Polymer dispersed liquid crystal thin films have been deposited on glass substrates by the processes of polymerization and solvent evaporation induced phase separation. The electron and the optical polarization microscopies of the films reveal that PDLC microdroplets formed during the process of phase separation near the top surface of the film remain exposed and respond to shear stress due to air or gas flow on the surface. Optical response of the film to an air flow-induced shear stress input on the free surface has been measured. Director orientation in the droplets changes with the applied shear stress leading to time varying transmitted light intensity. Director dynamics of the droplet for an applied step shear stress has been discussed from free energy considerations. Results on the measurement of light transmission as a function of the gas flow parameter unambiguously demonstrate the potential of these systems for use as boundary layer and gas flow sensors.

NMRI Measurements of Flow of Granular Mixtures

NASA Technical Reports Server (NTRS)

Nakagawa, Masami; Waggoner, R. Allen; Fukushima, Eiichi

1996-01-01

We investigate complex 3D behavior of granular mixtures in shaking and shearing devices. NMRI can non-invasively measure concentration, velocity, and velocity fluctuations of flows of suitable particles. We investigate origins of wall-shear induced convection flow of single component particles by measuring the flow and fluctuating motion of particles near rough boundaries. We also investigate if a mixture of different size particles segregate into their own species under the influence of external shaking and shearing disturbances. These non-invasive measurements will reveal true nature of convecting flow properties and wall disturbance. For experiments in a reduced gravity environment, we will design a light weight NMR imager. The proof of principle development will prepare for the construction of a complete spaceborne system to perform experiments in space.

Combinational concentration gradient confinement through stagnation flow.

PubMed

Alicia, Toh G G; Yang, Chun; Wang, Zhiping; Nguyen, Nam-Trung

2016-01-21

Concentration gradient generation in microfluidics is typically constrained by two conflicting mass transport requirements: short characteristic times (τ) for precise temporal control of concentration gradients but at the expense of high flow rates and hence, high flow shear stresses (σ). To decouple the limitations from these parameters, here we propose the use of stagnation flows to confine concentration gradients within large velocity gradients that surround the stagnation point. We developed a modified cross-slot (MCS) device capable of feeding binary and combinational concentration sources in stagnation flows. We show that across the velocity well, source-sink pairs can form permanent concentration gradients. As source-sink concentration pairs are continuously supplied to the MCS, a permanently stable concentration gradient can be generated. Tuning the flow rates directly controls the velocity gradients, and hence the stagnation point location, allowing the confined concentration gradient to be focused. In addition, the flow rate ratio within the MCS rapidly controls (τ ∼ 50 ms) the location of the stagnation point and the confined combinational concentration gradients at low flow shear (0.2 Pa < σ < 2.9 Pa). The MCS device described in this study establishes the method for using stagnation flows to rapidly generate and position low shear combinational concentration gradients for shear sensitive biological assays.

Effects of insulin on physical factors: atherosclerosis in diabetes mellitus.

PubMed

McMillan, D E

1985-12-01

Newton's laws of motion play a major role in blood flow. Inertia and conservation of momentum cause flow to separate at branches and curves in large blood vessels. Areas of separated flow in the arterial system are sites of atherogenesis. The place at which the separation ends, called the stagnation point, is the focus for plaque development. Pulsation of the arterial circulation causes the stagnation point to move downstream with each systole and upstream with each diastole. This movement generates forward and backward shearing force in the stagnation region as the separated flow migrates back and forth. Angular momentum, introduced into flowing blood with each heart beat and further enhanced by the asymmetry of origin of vessels branching from the aorta, generates a sidewise force component that is preserved during migration of the stagnation point. The sidewise force, added to the forward and backward shear stresses, creates an area of multidirectional shear stress under the migrating stagnation point that increases the permeability of the local endothelium. Blood is a complex fluid; it can generate greater shear stresses near the stagnation point than the simple fluids normally studied by fluid mechanicists. Blood is capable of retaining shear stress for short periods after it ceases to flow and extra work is required to establish its flow. In diabetes, reduced erythrocyte deformability further burdens flow onset. We are not yet able to establish whether the increase is only a few percent, or whether the burden is larger. Whatever its magnitude, diabetic modifications of the flow properties of blood, directly affect the size, location, and rate of development of atherosclerotic plaques.

The effect of inlet boundary conditions in image-based CFD modeling of aortic flow

NASA Astrophysics Data System (ADS)

Madhavan, Sudharsan; Kemmerling, Erica Cherry

2016-11-01

CFD of cardiovascular flow is a growing and useful field, but simulations are subject to a number of sources of uncertainty which must be quantified. Our work focuses on the uncertainty introduced by the selection of inlet boundary conditions in an image-based, patient-specific model of the aorta. Specifically, we examined the differences between plug flow, fully developed parabolic flow, linear shear flows, skewed parabolic flow profiles, and Womersley flow. Only the shape of the inlet velocity profile was varied-all other parameters were held constant between simulations, including the physiologically realistic inlet flow rate waveform and outlet flow resistance. We found that flow solutions with different inlet conditions did not exhibit significant differences beyond 1 . 75 inlet diameters from the aortic root. Time averaged wall shear stress (TAWSS) was also calculated. The linear shear velocity boundary condition solution exhibited the highest spatially averaged TAWSS, about 2 . 5 % higher than the fully developed parabolic velocity boundary condition, which had the lowest spatially averaged TAWSS.

NUMERICAL SIMULATION TO DETERMINE THE EFFECTS OF INCIDENT WIND SHEAR AND TURBULENCE LEVEL ON THE FLOW AROUND A BUILDING

EPA Science Inventory

The effects of incident shear and turbulence on flow around a cubical building are being investigated by a turbulent kinetic energy dissipation (k-e) model (TEMPEST). he numerical simulations demonstrate significant effects due to the differences in the incident flow. he addition...

Ultrasonic velocity profiling rheometry based on a widened circular Couette flow

NASA Astrophysics Data System (ADS)

Shiratori, Takahisa; Tasaka, Yuji; Oishi, Yoshihiko; Murai, Yuichi

2015-08-01

We propose a new rheometry for characterizing the rheological properties of fluids. The technique produces flow curves, which represent the relationship between the fluid shear rate and shear stress. Flow curves are obtained by measuring the circumferential velocity distribution of tested fluids in a circular Couette system, using an ultrasonic velocity profiling technique. By adopting a widened gap of concentric cylinders, a designed range of the shear rate is obtained so that velocity profile measurement along a single line directly acquires flow curves. To reduce the effect of ultrasonic noise on resultant flow curves, several fitting functions and variable transforms are examined to best approximate the velocity profile without introducing a priori rheological models. Silicone oil, polyacrylamide solution, and yogurt were used to evaluate the applicability of this technique. These substances are purposely targeted as examples of Newtonian fluids, shear thinning fluids, and opaque fluids with unknown rheological properties, respectively. We find that fourth-order Chebyshev polynomials provide the most accurate representation of flow curves in the context of model-free rheometry enabled by ultrasonic velocity profiling.

Time and flow-direction responses of shear-styress-sensitive liquid crystal coatings

NASA Technical Reports Server (NTRS)

Reda, Daniel C.; Muraqtore, J. J.; Heinick, James T.

1994-01-01

Time and flow-direction responses of shear-stress liquid crystal coatings were exploresd experimentally. For the time-response experiments, coatings were exposed to transient, compressible flows created during the startup and off-design operation of an injector-driven supersonic wind tunnel. Flow transients were visualized with a focusing schlieren system and recorded with a 100 frame/s color video camera.

Transverse electron-scale instability in relativistic shear flows.

PubMed

Alves, E P; Grismayer, T; Fonseca, R A; Silva, L O

2015-08-01

Electron-scale surface waves are shown to be unstable in the transverse plane of a sheared flow in an initially unmagnetized collisionless plasma, not captured by (magneto)hydrodynamics. It is found that these unstable modes have a higher growth rate than the closely related electron-scale Kelvin-Helmholtz instability in relativistic shears. Multidimensional particle-in-cell simulations verify the analytic results and further reveal the emergence of mushroomlike electron density structures in the nonlinear phase of the instability, similar to those observed in the Rayleigh Taylor instability despite the great disparity in scales and different underlying physics. This transverse electron-scale instability may play an important role in relativistic and supersonic sheared flow scenarios, which are stable at the (magneto)hydrodynamic level. Macroscopic (≫c/ωpe) fields are shown to be generated by this microscopic shear instability, which are relevant for particle acceleration, radiation emission, and to seed magnetohydrodynamic processes at long time scales.

Decay and growth laws in homogeneous shear turbulence

NASA Astrophysics Data System (ADS)

Briard, Antoine; Gomez, Thomas; Mons, Vincent; Sagaut, Pierre

2016-07-01

Homogeneous anisotropic turbulence has been widely studied in the past decades, both numerically and experimentally. Shear flows have received a particular attention because of the numerous physical phenomena they exhibit. In the present paper, both the decay and growth of anisotropy in homogeneous shear flows at high Reynolds numbers are revisited thanks to a recent eddy-damped quasi-normal Markovian closure adapted to homogeneous anisotropic turbulence. The emphasis is put on several aspects: an asymptotic model for the slow part of the pressure-strain tensor is derived for the return to isotropy process when mean velocity gradients are released. Then, a general decay law for purely anisotropic quantities in Batchelor turbulence is proposed. At last, a discussion is proposed to explain the scattering of global quantities obtained in DNS and experiments in sustained shear flows: the emphasis is put on the exponential growth rate of the kinetic energy and on the shear parameter.

Visualization of three pathways for macromolecule transport across cultured endothelium and their modification by flow.

PubMed

Ghim, Mean; Alpresa, Paola; Yang, Sung-Wook; Braakman, Sietse T; Gray, Stephen G; Sherwin, Spencer J; van Reeuwijk, Maarten; Weinberg, Peter D

2017-11-01

Transport of macromolecules across vascular endothelium and its modification by fluid mechanical forces are important for normal tissue function and in the development of atherosclerosis. However, the routes by which macromolecules cross endothelium, the hemodynamic stresses that maintain endothelial physiology or trigger disease, and the dependence of transendothelial transport on hemodynamic stresses are controversial. We visualized pathways for macromolecule transport and determined the effect on these pathways of different types of flow. Endothelial monolayers were cultured under static conditions or on an orbital shaker producing different flow profiles in different parts of the wells. Fluorescent tracers that bound to the substrate after crossing the endothelium were used to identify transport pathways. Maps of tracer distribution were compared with numerical simulations of flow to determine effects of different shear stress metrics on permeability. Albumin-sized tracers dominantly crossed the cultured endothelium via junctions between neighboring cells, high-density lipoprotein-sized tracers crossed at tricellular junctions, and low-density lipoprotein-sized tracers crossed through cells. Cells aligned close to the angle that minimized shear stresses across their long axis. The rate of paracellular transport under flow correlated with the magnitude of these minimized transverse stresses, whereas transport across cells was uniformly reduced by all types of flow. These results contradict the long-standing two-pore theory of solute transport across microvessel walls and the consensus view that endothelial cells align with the mean shear vector. They suggest that endothelial cells minimize transverse shear, supporting its postulated proatherogenic role. Preliminary data show that similar tracer techniques are practicable in vivo. NEW & NOTEWORTHY Solutes of increasing size crossed cultured endothelium through intercellular junctions, through tricellular junctions, or transcellularly. Cells aligned to minimize the shear stress acting across their long axis. Paracellular transport correlated with the level of this minimized shear, but transcellular transport was reduced uniformly by flow regardless of the shear profile. Copyright © 2017 the American Physiological Society.

Nonuniform flow in soft glasses of colloidal rods

NASA Astrophysics Data System (ADS)

Dhont, J. K. G.; Kang, K.; Kriegs, H.; Danko, O.; Marakis, J.; Vlassopoulos, D.

2017-04-01

Despite our reasonably advanced understanding of the dynamics and flow of glasses made of spherical colloids, the role of shape, i.e., the respective behavior of glasses formed by rodlike, particles is virtually unexplored. Recently, long, thin and highly charged rods (fd-virus particles) were found to vitrify in aqueous suspensions at low ionic strength [Phys. Rev. Lett. 110, 015901 (2013), 10.1103/PhysRevLett.110.015901]. The glass transition of these long-ranged repulsive rods occurs at a concentration far above the isotropic-nematic coexistence region and is characterized by the unique arrest of both the dynamics of domains that constitute the chiral-nematic orientational texture, as well as individual rods inside the domains. Hence, two relevant length scales exist: the domain size of a few hundreds of microns, and the rod-cage size of a few microns, inside the domains. We show that the unique dual dynamic arrest and the existing of two widely separated length scales imparts an unprecedented, highly heterogeneous flow behavior with three distinct signatures. Beyond a weak stress plateau at very small shear rates that characterizes the glass, the kinetic arrest of the domain dynamics gives rise to internal fracture, as a result of domain-domain interactions, as well as wall partial slip. It is shown that, on increasing the shear rate, the fractured plug flow changes to a shear-banded flow profile due to the stress response of the kinetically arrested aligned rods within the domains. Shear-gradient banding occurs due to the strong thinning of the uniform chiral-nematic phase within the domains, i.e., complying with the classic shear-banding scenario, giving rise to a stress plateau in the flow curve. Finally, a linear (uniform) velocity profile is found at the highest shear rates. Vorticity banding is also observed at intermediate and high shear rates. These results point to the crucial role of particle shape in tailoring the flow properties of dense colloidal suspensions. Moreover, they strongly support the argument that the origin of shear banding in soft-particle glasses with long-ranged repulsive interactions is fundamentally different from that of hard-particle glasses with short-ranged repulsive interactions.

Flow Enhancement due to Elastic Turbulence in Channel Flows of Shear Thinning Fluids

NASA Astrophysics Data System (ADS)

Bodiguel, Hugues; Beaumont, Julien; Machado, Anaïs; Martinie, Laetitia; Kellay, Hamid; Colin, Annie

2015-01-01

We explore the flow of highly shear thinning polymer solutions in straight geometry. The strong variations of the normal forces close to the wall give rise to an elastic instability. We evidence a periodic motion close the onset of the instability, which then evolves towards a turbulentlike flow at higher flow rates. Strikingly, we point out that this instability induces genuine drag reduction due to the homogenization of the viscosity profile by the turbulent flow.

Flow enhancement due to elastic turbulence in channel flows of shear thinning fluids.

PubMed

Bodiguel, Hugues; Beaumont, Julien; Machado, Anaïs; Martinie, Laetitia; Kellay, Hamid; Colin, Annie

2015-01-16

We explore the flow of highly shear thinning polymer solutions in straight geometry. The strong variations of the normal forces close to the wall give rise to an elastic instability. We evidence a periodic motion close the onset of the instability, which then evolves towards a turbulentlike flow at higher flow rates. Strikingly, we point out that this instability induces genuine drag reduction due to the homogenization of the viscosity profile by the turbulent flow.

Applying a general triclinic transpression model to highly partitioned brittle-ductile shear zones: A case study from the Torcal de Antequera massif, external Betics, southern Spain

NASA Astrophysics Data System (ADS)

Díaz-Azpiroz, M.; Barcos, L.; Balanyá, J. C.; Fernández, C.; Expósito, I.; Czeck, D. M.

2014-11-01

Oblique convergence and subsequent transpression kinematics can be considered as the general situation in most convergent and strike-slip tectonic boundaries. To better understand such settings, progressively more complex kinematic models have been proposed, which need to be tested against natural shear zones using standardized procedures that minimise subjectivism. In this work, a protocol to test a general triclinic transpression model is applied to the Torcal de Antequera massif (TAM), an essentially brittle shear zone. Our results, given as kinematic parameters of the transpressive flow (transpression obliquity, ϕ; extrusion obliquity, υ; and kinematic vorticity number, Wk), suggest that the bulk triclinic transpressive flow imposed on the TAM was partitioned into two different flow fields, following a general partitioning type. As such, one flow field produced narrow structural domains located at the limits of the TAM, where mainly dextral strike-slip simple-shear-dominated transpression took place (Outer domains, ODs). In contrast, the remaining part of the bulk flow produced pure-shear-dominated dextral triclinic transpression at the inner part of the TAM (Inner domain, ID). A graphical method relating internal (ϕ, Wk) to far-field (dip of the shear zone boundary, δ; angle of oblique convergence, α) transpression parameters is proposed to obtain the theoretical horizontal velocity vector (V→), which in the case of the TAM, ranges between 099 and 118. These results support the applicability of kinematic models of triclinic transpression to brittle-ductile shear zones and the potential utility of the proposed protocol.

Breaking symmetry in non-planar bifurcations: distribution of flow and wall shear stress.

PubMed

Lu, Yiling; Lu, Xiyun; Zhuang, Lixian; Wang, Wen

2002-01-01

Non-planarity in blood vessels is known to influence arterial flows and wall shear stress. To gain insight, computational fluid dynamics (CFD) has been used to investigate effects of curvature and out-of-plane geometry on the distribution of fluid flows and wall shear stresses in a hypothetical non-planar bifurcation. Three-dimensional Navier-Stokes equations for a steady state Newtonian fluid were solved numerically using a finite element method. Non-planarity in one of the two daughter vessels is found to deflect flow from the inner wall of the vessel to the outer wall and to cause changes in the distribution of wall shear stresses. Results from this study agree to experimental observations and CFD simulations in the literature, and support the view that non-planarity in blood vessels is a factor with important haemodynamic significance and may play a key role in vascular biology and pathophysiology.

Measurement of shear-induced diffusion of red blood cells using dynamic light scattering-optical coherence tomography

NASA Astrophysics Data System (ADS)

Tang, Jianbo; Erdener, Sefik Evren; Li, Baoqiang; Fu, Buyin; Sakadzic, Sava; Carp, Stefan A.; Lee, Jonghwan; Boas, David A.

2018-02-01

Dynamic Light Scattering-Optical Coherence Tomography (DLS-OCT) takes the advantages of using DLS to measure particle flow and diffusion within an OCT resolution-constrained 3D volume, enabling the simultaneous measurements of absolute RBC velocity and diffusion coefficient with high spatial resolution. In this work, we applied DLS-OCT to measure both RBC velocity and the shear-induced diffusion coefficient within penetrating venules of the somatosensory cortex of anesthetized mice. Blood flow laminar profile measurements indicate a blunted laminar flow profile, and the degree of blunting decreases with increasing vessel diameter. The measured shear-induced diffusion coefficient was proportional to the flow shear rate with a magnitude of 0.1 to 0.5 × 10-6 mm2 . These results provide important experimental support for the recent theoretical explanation for why DCS is dominantly sensitive to RBC diffusive motion.

Microbubble Sizing and Shell Characterization Using Flow Cytometry

PubMed Central

Tu, Juan; Swalwell, Jarred E.; Giraud, David; Cui, Weicheng; Chen, Weizhong; Matula, Thomas J.

2015-01-01

Experiments were performed to size, count, and obtain shell parameters for individual ultrasound contrast microbubbles using a modified flow cytometer. Light scattering was modeled using Mie theory, and applied to calibration beads to calibrate the system. The size distribution and population were measured directly from the flow cytometer. The shell parameters (shear modulus and shear viscosity) were quantified at different acoustic pressures (from 95 to 333 kPa) by fitting microbubble response data to a bubble dynamics model. The size distribution of the contrast agent microbubbles is consistent with manufacturer specifications. The shell shear viscosity increases with increasing equilibrium microbubble size, and decreases with increasing shear rate. The observed trends are independent of driving pressure amplitude. The shell elasticity does not vary with microbubble size. The results suggest that a modified flow cytometer can be an effective tool to characterize the physical properties of microbubbles, including size distribution, population, and shell parameters. PMID:21622051

Upward swimming of a sperm cell in shear flow.

PubMed

Omori, Toshihiro; Ishikawa, Takuji

2016-03-01

Mammalian sperm cells are required to swim over long distances, typically around 1000-fold their own length. They must orient themselves and maintain a swimming motion to reach the ovum, or egg cell. Although the mechanism of long-distance navigation is still unclear, one possible mechanism, rheotaxis, was reported recently. This work investigates the mechanism of the rheotaxis in detail by simulating the motions of a sperm cell in shear flow adjacent to a flat surface. A phase diagram was developed to show the sperm's swimming motion under different shear rates, and for varying flagellum waveform conditions. The results showed that, under shear flow, the sperm is able to hydrodynamically change its swimming direction, allowing it to swim upwards against the flow, which suggests that the upward swimming of sperm cells can be explained using fluid mechanics, and this can then be used to further understand physiology of sperm cell navigation.

SHEAR ACCELERATION IN EXPANDING FLOWS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rieger, F. M.; Duffy, P., E-mail: frank.rieger@mpi-hd.mpg.de, E-mail: peter.duffy@ucd.ie

Shear flows are naturally expected to occur in astrophysical environments and potential sites of continuous non-thermal Fermi-type particle acceleration. Here we investigate the efficiency of expanding relativistic outflows to facilitate the acceleration of energetic charged particles to higher energies. To this end, the gradual shear acceleration coefficient is derived based on an analytical treatment. The results are applied to the context of the relativistic jets from active galactic nuclei. The inferred acceleration timescale is investigated for a variety of conical flow profiles (i.e., power law, Gaussian, Fermi–Dirac) and compared to the relevant radiative and non-radiative loss timescales. The results exemplifymore » that relativistic shear flows are capable of boosting cosmic-rays to extreme energies. Efficient electron acceleration, on the other hand, requires weak magnetic fields and may thus be accompanied by a delayed onset of particle energization and affect the overall jet appearance (e.g., core, ridge line, and limb-brightening).« less

Velocity shear, turbulent saturation, and steep plasma gradients in the scrape-off layer of inner-wall limited tokamaks

DOE PAGES

Halpern, Federico D.; Ricci, Paolo

2016-12-19

The narrow power decay-length (λ q), recently found in the scrape-off layer (SOL) of inner wall limited (IWL) discharges in tokamaks, is studied using 3D, flux-driven, global two fluid turbulence simulations. The formation of the steep plasma profiles is found to arise due to radially sheared E×B poloidal flows. A complex interaction between sheared flows and parallel plasma currents outflowing into the sheath regulates the turbulent saturation, determining the transport levels. We quantify the effects of sheared flows, obtaining theoretical estimates in agreement with our non-linear simulations. As a result, analytical calculations suggest that the IWL λ q is roughlymore » equal to the turbulent correlation length.« less

Active dynamics of tissue shear flow

NASA Astrophysics Data System (ADS)

Popović, Marko; Nandi, Amitabha; Merkel, Matthias; Etournay, Raphaël; Eaton, Suzanne; Jülicher, Frank; Salbreux, Guillaume

2017-03-01

We present a hydrodynamic theory to describe shear flows in developing epithelial tissues. We introduce hydrodynamic fields corresponding to state properties of constituent cells as well as a contribution to overall tissue shear flow due to rearrangements in cell network topology. We then construct a generic linear constitutive equation for the shear rate due to topological rearrangements and we investigate a novel rheological behaviour resulting from memory effects in the tissue. We identify two distinct active cellular processes: generation of active stress in the tissue, and actively driven topological rearrangements. We find that these two active processes can produce distinct cellular and tissue shape changes, depending on boundary conditions applied on the tissue. Our findings have consequences for the understanding of tissue morphogenesis during development.

Direct simulation of compressible turbulence in a shear flow

NASA Technical Reports Server (NTRS)

Sarkar, S.; Erlebacher, G.; Hussaini, M. Y.

1991-01-01

The purpose of this study is to investigate compressibility effects on the turbulence in homogeneous shear flow. It is found that the growth of the turbulent kinetic energy decreases with increasing Mach number, a phenomenon similar to the reduction of turbulent velocity intensities observed in experiments on supersonic free shear layers. An examination of the turbulent energy budget shows that both the compressible dissipation and the pressure-dilatation contribute to the decrease in the growth of kinetic energy. The pressure-dilatation is predominantly negative in homogeneous shear flow, in contrast to its predominantly positive behavior in isotropic turbulence. The different signs of the pressure-dilatation are explained by theoretical consideration of the equations for the pressure variance and density variance.

In-situ temperature-controllable shear flow device for neutron scattering measurement—An example of aligned bicellar mixtures

DOE Office of Scientific and Technical Information (OSTI.GOV)

Xia, Yan; Li, Ming; Kučerka, Norbert

We have designed and constructed a temperature-controllable shear flow cell for in-situ study on flow alignable systems. The device has been tested in the neutron diffraction and has the potential to be applied in the small angle neutron scattering configuration to characterize the nanostructures of the materials under flow. The required sample amount is as small as 1 ml. The shear rate on the sample is controlled by the flow rate produced by an external pump and can potentially vary from 0.11 to 3.8 × 10{sup 5} s{sup −1}. Both unidirectional and oscillational flows are achievable by the setting ofmore » the pump. The instrument is validated by using a lipid bicellar mixture, which yields non-alignable nanodisc-like bicelles at low T and shear-alignable membranes at high T. Using the shear cell, the bicellar membranes can be aligned at 31 °C under the flow with a shear rate of 11.11 s{sup −1}. Multiple high-order Bragg peaks are observed and the full width at half maximum of the “rocking curve” around the Bragg’s condition is found to be 3.5°–4.1°. It is noteworthy that a portion of the membranes remains aligned even after the flow stops. Detailed and comprehensive intensity correction for the rocking curve has been derived based on the finite rectangular sample geometry and the absorption of the neutrons as a function of sample angle [See supplementary material at http://dx.doi.org/10.1063/1.4908165 for the detailed derivation of the absorption correction]. The device offers a new capability to study the conformational or orientational anisotropy of the solvated macromolecules or aggregates induced by the hydrodynamic interaction in a flow field.« less

Evaluation of Aortic Blood Flow and Wall Shear Stress in Aortic Stenosis and Its Association With Left Ventricular Remodeling.

PubMed

von Knobelsdorff-Brenkenhoff, Florian; Karunaharamoorthy, Achudhan; Trauzeddel, Ralf Felix; Barker, Alex J; Blaszczyk, Edyta; Markl, Michael; Schulz-Menger, Jeanette

2016-03-01

Aortic stenosis (AS) leads to variable stress for the left ventricle (LV) and consequently a broad range of LV remodeling. The aim of this study was to describe blood flow patterns in the ascending aorta of patients with AS and determine their association with remodeling. Thirty-seven patients with AS (14 mild, 8 moderate, 15 severe; age, 63±13 years) and 37 healthy controls (age, 60±10 years) underwent 4-dimensional-flow magnetic resonance imaging. Helical and vortical flow formations and flow eccentricity were assessed in the ascending aorta. Normalized flow displacement from the vessel center and peak systolic wall shear stress in the ascending aorta were quantified. LV remodeling was assessed based on LV mass index and the ratio of LV mass:end-diastolic volume (relative wall mass). Marked helical and vortical flow formation and eccentricity were more prevalent in patients with AS than in healthy subjects, and patients with AS exhibited an asymmetrical and elevated distribution of peak systolic wall shear stress. In AS, aortic orifice area was strongly negatively associated with vortical flow formation (P=0.0274), eccentricity (P=0.0070), and flow displacement (P=0.0021). Bicuspid aortic valve was associated with more intense helical (P=0.0098) and vortical flow formation (P=0.0536), higher flow displacement (P=0.11), and higher peak systolic wall shear stress (P=0.0926). LV mass index and relative wall mass were significantly associated with aortic orifice area (P=0.0611, P=0.0058) and flow displacement (P=0.0058, P=0.0283). In this pilot study, AS leads to abnormal blood flow pattern and peak systolic wall shear stress in the ascending aorta. In addition to aortic orifice area, normalized flow displacement was significantly associated with LV remodeling. © 2016 American Heart Association, Inc.

Measurement of surface shear stress vector beneath high-speed jet flow using liquid crystal coating

NASA Astrophysics Data System (ADS)

Wang, Cheng-Peng; Zhao, Ji-Song; Jiao, Yun; Cheng, Ke-Ming

2018-05-01

The shear-sensitive liquid crystal coating (SSLCC) technique is investigated in the high-speed jet flow of a micro-wind-tunnel. An approach to measure surface shear stress vector distribution using the SSLCC technique is established, where six synchronous cameras are used to record the coating color at different circumferential view angles. Spatial wall shear stress vector distributions on the test surface are obtained at different velocities. The results are encouraging and demonstrate the great potential of the SSLCC technique in high-speed wind-tunnel measurement.

Visualization of boundary-layer development on turbomachine blades with liquid crystals

NASA Technical Reports Server (NTRS)

Vanzante, Dale E.; Okiishi, Theodore H.

1991-01-01

This report documents a study of the use of liquid crystals to visualize boundary layer development on a turbomachine blade. A turbine blade model in a linear cascade of blades was used for the tests involved. Details of the boundary layer development on the suction surface of the turbine blade model were known from previous research. Temperature sensitive and shear sensitive liquid crystals were tried as visual agents. The temperature sensitive crystals were very effective in their ability to display the location of boundary layer flow separation and reattachment. Visualization of natural transition from laminar to turbulent boundary layer flow with the temperature sensitive crystals was possible but subtle. The visualization of separated flow reattachment with the shear sensitive crystals was easily accomplished when the crystals were allowed to make a transition from the focal-conic to a Grandjean texture. Visualization of flow reattachment based on the selective reflection properties of shear sensitive crystals was achieved only marginally because of the larger surface shear stress and shear stress gradient levels required for more dramatic color differences.

Shear-Flow Instability Saturation by Stable Modes: Hydrodynamics and Gyrokinetics

NASA Astrophysics Data System (ADS)

Fraser, Adrian; Pueschel, M. J.; Terry, P. W.; Zweibel, E. G.

2017-10-01

We present simulations of shear-driven instabilities, focusing on the impact of nonlinearly excited, large-scale, linearly stable modes on the nonlinear cascade, momentum transport, and secondary instabilities. Stable modes, which have previously been shown to significantly affect instability saturation [Fraser et al. PoP 2017], are investigated in a collisionless, gyrokinetic, periodic zonal flow using the Gene code by projecting the results of nonlinear simulations onto a basis of linear eigenmodes that includes both stable and unstable modes. Benchmarking growth rates against previous gyrokinetic studies and an equivalent fluid system demonstrates comparable linear dynamics in the fluid and gyrokinetic systems. Cases of driven and decaying shear-flow turbulence are compared in Gene by using a Krook operator as an effective forcing. For comparison with existing hydrodynamic and MHD shear-flow instability studies, we present results for the shear layer obtained by similar means with the code Dedalus. Supported by U.S. DOE Grant No. DE-FG02-89ER53291, the NSF, and UW-Madison.

Effect of simple shear flow on photosynthesis rate and morphology of micro algae

NASA Astrophysics Data System (ADS)

Mitsuhashi, S.; Fujimoto, M.; Muramatsu, H.; Tanishita, K.

The convective motion of micro algal suspension gives an advantageous effect on the photosynthetic rate in the bioreactor, however, the nature of convective effect on the photosynthesis has not been fully understood. The propose of this study concerns the nature of photosynthetic rate in a well-defined hydrodynamic shear flow of Spirulina platensis suspension, generated in a double rotating coaxial cylinders. The double rotating coaxial cylinders was installed in the incubator chamber with the controlled illumination intensity and temperature. Two kind of experiments, short and long term experiments, were performed to evaluate the direct effect of shear flow on the photosynthetic rate. The short term experiment indicates that the simple shear flow enables to augment the photosynthesis of Spirulina suspension and simultaneously causes the cell destruction due to the excessive shear stress. The long term experiment for 100 hours reveals that the growth rate and the morphology of Spirulina is sensitive to the external fluid mechanical stimulus. The long term application of mechanical stress on the algae may result in the adaptation of the photosynthetic function and morphology.

Molecular characteristics of stress overshoot for polymer melts under start-up shear flow.

PubMed

Jeong, Sohdam; Kim, Jun Mo; Baig, Chunggi

2017-12-21

Stress overshoot is one of the most important nonlinear rheological phenomena exhibited by polymeric liquids undergoing start-up shear at sufficient flow strengths. Despite considerable previous research, the fundamental molecular characteristics underlying stress overshoot remain unknown. Here, we analyze the intrinsic molecular mechanisms behind the overshoot phenomenon using atomistic nonequilibrium molecular dynamics simulations of entangled linear polyethylene melts under shear flow. Through a detailed analysis of the transient rotational chain dynamics, we identify an intermolecular collision angular regime in the vicinity of the chain orientation angle θ ≈ 20° with respect to the flow direction. The shear stress overshoot occurs via strong intermolecular collisions between chains in the collision regime at θ = 15°-25°, corresponding to a peak strain of 2-4, which is an experimentally well-known value. The normal stress overshoot appears at approximately θ = 10°, at a corresponding peak strain roughly equivalent to twice that for the shear stress. We provide plausible answers to several basic questions regarding the stress overshoot, which may further help understand other nonlinear phenomena of polymeric systems.

Compact type-I coil planet centrifuge for counter-current chromatography

PubMed Central

Yang, Yi; Gu, Dongyu; Liu, Yongqiang; Aisa, Haji Akber; Ito, Yoichiro

2009-01-01

A compact type-I coil planet centrifuge has been developed for performing counter-current chromatography. It has a revolution radius of 10 cm and a column holder height of 5 cm compared with 37 cm and 50 cm in the original prototype, respectively. The reduction in the revolution radius and column length permits application of higher revolution speed and more stable balancing of the rotor which leads us to learn more about its performance and the future potential of type-I coil planet centrifuge. The chromatographic performance of this apparatus was evaluated in terms of retention of the stationary phase (Sf), peak resolution (Rs), theoretical plate (N) and peak retention time (tR). The results of the experiment indicated that increasing the revolution speed slightly improved both the retention of the stationary phase and the peak resolution while the separation time is remarkably shortened to yield an excellent peak resolution at a revolution speed of 800 rpm. With a 12 ml capacity coiled column, DNP-glu, DNP-β-ala and DNP-ala were resolved at Rs of 2.75 and 2.16 within 90 min at a flow rate of 0.4 ml/min. We believe that the compact type-I coil planet centrifuge has a high analytical potential. PMID:20060979

Compact type-I coil planet centrifuge for counter-current chromatography.

PubMed

Yang, Yi; Gu, Dongyu; Liu, Yongqiang; Aisa, Haji Akber; Ito, Yoichiro

2010-02-19

A compact type-I coil planet centrifuge has been developed for performing counter-current chromatography. It has a revolution radius of 10 cm and a column holder height of 5 cm compared with 37 and 50 cm in the original prototype, respectively. The reduction in the revolution radius and column length permits application of higher revolution speed and more stable balancing of the rotor which leads us to learn more about its performance and the future potential of type-I coil planet centrifuge. The chromatographic performance of this apparatus was evaluated in terms of retention of the stationary phase (S(f)), peak resolution (R(s)), theoretical plate (N) and peak retention time (t(R)). The results of the experiment indicated that increasing the revolution speed slightly improved both the retention of the stationary phase and the peak resolution while the separation time is remarkably shortened to yield an excellent peak resolution at a revolution speed of 800 rpm. With a 12 ml capacity coiled column, DNP-DL-glu, DNP-beta-ala and DNP-l-ala were resolved at R(s) of 2.75 and 2.16 within 90 min at a flow rate of 0.4 ml/min. We believe that the compact type-I coil planet centrifuge has a high analytical potential. Published by Elsevier B.V.

High Temperature Heat Exchanger Design and Fabrication for Systems with Large Pressure Differentials

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chordia, Lalit; Portnoff, Marc A.; Green, Ed

The project’s main purpose was to design, build and test a compact heat exchanger for supercritical carbon dioxide (sCO 2) power cycle recuperators. The compact recuperator is required to operate at high temperature and high pressure differentials, 169 bar (~2,500 psi), between streams of sCO 2. Additional project tasks included building a hot air-to-sCO 2 Heater heat exchanger (HX) and design, build and operate a test loop to characterize the recuperator and heater heat exchangers. A novel counter-current microtube recuperator was built to meet the high temperature high differential pressure criteria and tested. The compact HX design also incorporated amore » number of features that optimize material use, improved reliability and reduced cost. The air-to-sCO 2 Heater HX utilized a cross flow, counter-current, micro-tubular design. This compact HX design was incorporated into the test loop and exceeded design expectations. The test loop design to characterize the prototype Brayton power cycle HXs was assembled, commissioned and operated during the program. Both the prototype recuperator and Heater HXs were characterized. Measured results for the recuperator confirmed the predictions of the heat transfer models developed during the project. Heater HX data analysis is ongoing.« less

Characterizing the interaction between enantiomers of eight psychoactive drugs and highly sulfated-β-cyclodextrin by counter-current capillary electrophoresis.

PubMed

Asensi-Bernardi, Lucía; Escuder-Gilabert, Laura; Martín-Biosca, Yolanda; Sagrado, Salvador; Medina-Hernández, María José

2014-01-01

The estimation of apparent binding constants and limit mobilities of the complexes of the enantiomers that characterize the interaction of enantiomers with chiral selectors, in this case highly sulfated β-cyclodextrin, was approached using a simple and economic electrophoretic modality, the complete filling technique (CFT) in counter-current mode. The enantiomers of eight psychoactive drugs, four antihistamines (dimethindene, promethazine, orphenadrine and terfenadine) and four antidepressants (bupropion, fluoxetine, nomifensine and viloxazine) were separated for the first time for this cyclodextrin (CD). Estimations of thermodynamic and electrophoretic enantioselectivies were also performed. Results indicate that, in general, thermodynamic enantioselectivity is the main component explaining the high resolution found, but also one case suggests that electrophoretic enantioselectivity itself is enough to obtain a satisfactory resolution. CFT results advantageous compared with conventional capillary electrophoresis (CE) and partial filling technique (PFT) for the study of the interaction between drugs and chiral selectors. It combines the use of a simple fitting model (as in CE), when the enantiomers do not exit the chiral selector plug during the separation (i.e. mobility of electroosmotic flow larger than mobility of CD), and drastic reduction of the consumption (and cost; ~99.7%) of the CD reagent (as in PFT) compared with the conventional CE. Copyright © 2013 John Wiley & Sons, Ltd.

Magnetic resonance imaging 4-D flow-based analysis of aortic hemodynamics in Turner syndrome.

PubMed

Arnold, Raoul; Neu, Marie; Hirtler, Daniel; Gimpel, Charlotte; Markl, Michael; Geiger, Julia

2017-04-01

Cardiovascular surveillance is important in Turner syndrome because of the increased risk of aortic dilation and dissection with consecutively increased mortality. To compare 4-D flow MRI for the characterization of aortic 3-D flow patterns, dimensions and vessel wall parameters in pediatric patients with Turner syndrome and age-matched controls. We performed 4-D flow MRI measuring in vivo 3-D blood flow with coverage of the thoracic aorta in 25 patients with Turner syndrome and in 16 female healthy controls (age mean ± standard deviation were 16 ± 5 years and 17 ± 4 years, respectively). Blood flow was visualized by time-resolved 3-D path lines. Visual grading of aortic flow in terms of helices and vortices was performed by two independent observers. Quantitative analysis included measurement of aortic diameters, quantification of peak systolic wall shear stress, pulsatility index and oscillatory shear index at eight defined sites. Patients with Turner syndrome had significantly larger aortic diameters normalized to BSA, increased vortices in the ascending aorta and elevated helix flow in the ascending and descending aorta compared to controls (all P<0.03). Patients with abnormal helical or vortical flow in the ascending aorta had significantly larger diameters of the ascending aorta (P<0.03). Peak systolic wall shear stress, pulsatility index and oscillatory shear index were significantly lower in Turner patients compared to controls (p=0.02, p=0.002 and p=0.01 respectively). Four-dimensional flow MRI provides new insights into the altered aortic hemodynamics and wall shear stress that could have an impact on the development of aortic dissections.

Fourier decomposition of polymer orientation in large-amplitude oscillatory shear flow

DOE PAGES

Giacomin, A. J.; Gilbert, P. H.; Schmalzer, A. M.

2015-03-19

In our previous work, we explored the dynamics of a dilute suspension of rigid dumbbells as a model for polymeric liquids in large-amplitude oscillatory shear flow, a flow experiment that has gained a significant following in recent years. We chose rigid dumbbells since these are the simplest molecular model to give higher harmonics in the components of the stress response. We derived the expression for the dumbbell orientation distribution, and then we used this function to calculate the shear stress response, and normal stress difference responses in large-amplitude oscillatory shear flow. In this paper, we deepen our understanding of themore » polymer motion underlying large-amplitude oscillatory shear flow by decomposing the orientation distribution function into its first five Fourier components (the zeroth, first, second, third, and fourth harmonics). We use three-dimensional images to explore each harmonic of the polymer motion. Our analysis includes the three most important cases: (i) nonlinear steady shear flow (where the Deborah number λω is zero and the Weissenberg number λγ 0 is above unity), (ii) nonlinear viscoelasticity (where both λω and λγ 0 exceed unity), and (iii) linear viscoelasticity (where λω exceeds unity and where λγ 0 approaches zero). We learn that the polymer orientation distribution is spherical in the linear viscoelastic regime, and otherwise tilted and peanut-shaped. We find that the peanut-shaping is mainly caused by the zeroth harmonic, and the tilting, by the second. The first, third, and fourth harmonics of the orientation distribution make only slight contributions to the overall polymer motion.« less

Extension of a System Level Tool for Component Level Analysis

NASA Technical Reports Server (NTRS)

Majumdar, Alok; Schallhorn, Paul

2002-01-01

This paper presents an extension of a numerical algorithm for network flow analysis code to perform multi-dimensional flow calculation. The one dimensional momentum equation in network flow analysis code has been extended to include momentum transport due to shear stress and transverse component of velocity. Both laminar and turbulent flows are considered. Turbulence is represented by Prandtl's mixing length hypothesis. Three classical examples (Poiseuille flow, Couette flow and shear driven flow in a rectangular cavity) are presented as benchmark for the verification of the numerical scheme.

Extension of a System Level Tool for Component Level Analysis

NASA Technical Reports Server (NTRS)

Majumdar, Alok; Schallhorn, Paul; McConnaughey, Paul K. (Technical Monitor)

2001-01-01

This paper presents an extension of a numerical algorithm for network flow analysis code to perform multi-dimensional flow calculation. The one dimensional momentum equation in network flow analysis code has been extended to include momentum transport due to shear stress and transverse component of velocity. Both laminar and turbulent flows are considered. Turbulence is represented by Prandtl's mixing length hypothesis. Three classical examples (Poiseuille flow, Couette flow, and shear driven flow in a rectangular cavity) are presented as benchmark for the verification of the numerical scheme.

Two-dimensional dynamics of a trapped active Brownian particle in a shear flow

NASA Astrophysics Data System (ADS)

Li, Yunyun; Marchesoni, Fabio; Debnath, Tanwi; Ghosh, Pulak K.

2017-12-01

We model the two-dimensional dynamics of a pointlike artificial microswimmer diffusing in a harmonic trap subject to the shear flow of a highly viscous medium. The particle is driven simultaneously by the linear restoring force of the trap, the drag force exerted by the flow, and the torque due to the shear gradient. For a Couette flow, elliptical orbits in the noiseless regime, and the correlation functions between the particle's displacements parallel and orthogonal to the flow are computed analytically. The effects of thermal fluctuations (translational) and self-propulsion fluctuations (angular) are treated separately. Finally, we discuss how to extend our approach to the diffusion of a microswimmer in a Poiseuille flow. These results provide an accurate reference solution to investigate, both numerically and experimentally, hydrodynamics corrections to the diffusion of active matter in confined geometries.

Counter-current carbon dioxide extraction of fat from soy skim

USDA-ARS?s Scientific Manuscript database

This research aims to investigate the use of counter-current carbon dioxide extraction method as a means to reduce residual fat in soy skim after the enzyme-assisted aqueous extraction of soybeans. Extractions with liquid CO2 at 25°C and 10.34 MPa and supercritical CO2 at 50°C and 25.16 MPa are comp...

Acoustic wave propagation in a temporal evolving shear-layer for low-Mach number perturbations

NASA Astrophysics Data System (ADS)

Hau, Jan-Niklas; Müller, Björn

2018-01-01

We study wave packets with the small perturbation/gradient Mach number interacting with a smooth shear-layer in the linear regime of small amplitude perturbations. In particular, we investigate the temporal evolution of wave packets in shear-layers with locally curved regions of variable size using non-modal linear analysis and direct numerical simulations of the two-dimensional gas-dynamical equations. Depending on the wavenumber of the initially imposed wave packet, three different types of behavior are observed: (i) The wave packet passes through the shear-layer and constantly transfers energy back to the mean flow. (ii) It is turned around (or reflected) within the sheared region and extracts energy from the base flow. (iii) It is split into two oppositely propagating packages when reaching the upper boundary of the linearly sheared region. The conducted direct numerical simulations confirm that non-modal linear stability analysis is able to predict the wave packet dynamics, even in the presence of non-linearly sheared regions. In the light of existing studies in this area, we conclude that the sheared regions are responsible for the highly directed propagation of linearly generated acoustic waves when there is a dominating source, as it is the case for jet flows.

Isolation of a furan fatty acid from Hevea brasiliensis latex employing the combined use of pH-zone-refining and conventional countercurrent chromatography.

PubMed

Englert, Michael; Ulms, Kerstin; Wendlinger, Christine; Vetter, Walter

2016-02-01

Furan fatty acids are valuable and bioactive minor fatty acids that usually contribute <0.1% to the fatty acid content of food samples. Their biological role still remains unclear as authentic furan fatty acid standards are not readily available and thorough experimental studies verifying the relevance of furan fatty acids are thus virtually impossible. An efficient protocol for the isolation of the furan fatty acid 9-(3-methyl-5-pentylfuran-2-yl)-nonanoic acid from hydrolyzed and centrifuged latex of Hevea brasiliensis was developed using countercurrent chromatography. A first run using pH-zone-refining countercurrent chromatography provided 48.4 mg of 9-(3-methyl-5-pentylfuran-2-yl)-nonanoic acid from 210 mg latex extract in a purity of 95%. The purity was increased to 99% by means of one second run in conventional countercurrent chromatography mode. The Structure and purity of 9-(3-methyl-5-pentylfuran-2-yl)-nonanoic acid were determined by gas chromatography coupled to mass spectrometry and (1)H and (13)C NMR spectroscopy. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Effect of shear stress on the migration of hepatic stellate cells.

PubMed

Sera, Toshihiro; Sumii, Tateki; Fujita, Ryosuke; Kudo, Susumu

2018-01-01

When the liver is damaged, hepatic stellate cells (HSCs) can change into an activated, highly migratory state. The migration of HSCs may be affected by shear stress due not only to sinusoidal flow but also by the flow in the space of Disse because this space is filled with blood plasma. In this study, we evaluated the effects of shear stress on HSC migration in a scratch-wound assay with a parallel flow chamber. At regions upstream of the wound area, the migration was inhibited by 0.6 Pa and promoted by 2.0 Pa shear stress, compared to the static condition. The platelet-derived growth factor (PDGF)-BB receptor, PDGFR-β, was expressed in all conditions and the differences were not significant. PDGF increased HSC migration, except at 0.6 Pa shear stress, which was still inhibited. These results indicate that another molecular factor, such as PDGFR-α, may act to inhibit the migration under low shear stress. At regions downstream of the wound area, the migration was smaller under shear stress than under the static condition, although the expression of PDGFR-β was significantly higher. In particular, the migration direction was opposite to the wound area under high shear stress; therefore, migration might be influenced by the intercellular environment. Our results indicate that HSC migration was influenced by shear stress intensity and the intercellular environment.

Nonlinear Generation of shear flows and large scale magnetic fields by small scale

NASA Astrophysics Data System (ADS)

Aburjania, G.

2009-04-01

EGU2009-233 Nonlinear Generation of shear flows and large scale magnetic fields by small scale turbulence in the ionosphere by G. Aburjania Contact: George Aburjania, g.aburjania@gmail.com,aburj@mymail.ge

Nonmodal phenomena in differentially rotating dusty plasmas

NASA Astrophysics Data System (ADS)

Poedts, Stefaan; Rogava, Andria D.

2000-10-01

In this paper the foundation is layed for the nonmodal investigation of velocity shear induced phenomena in a differentially rotating flow of a dusty plasma. The simplest case of nonmagnetized flow is considered. It is shown that, together with the innate properties of the dusty plasma, the presence of differential rotation, Coriolis forces, and self-gravity casts a considerable richness on the nonmodal dynamics of linear perturbations in the flow. In particular: (i) dust-acoustic waves acquire the ability to extract energy from the mean flow and (ii) shear-induced, nonperiodic modes of collective plasma behavior-shear-dust-acoustic vortices-are generated. The presence of self-gravity and the nonzero Coriolis parameter (``epicyclic shaking'') makes these collective modes transiently unstable. .

A Two-length Scale Turbulence Model for Single-phase Multi-fluid Mixing

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schwarzkopf, J. D.; Livescu, D.; Baltzer, J. R.

2015-09-08

A two-length scale, second moment turbulence model (Reynolds averaged Navier-Stokes, RANS) is proposed to capture a wide variety of single-phase flows, spanning from incompressible flows with single fluids and mixtures of different density fluids (variable density flows) to flows over shock waves. The two-length scale model was developed to address an inconsistency present in the single-length scale models, e.g. the inability to match both variable density homogeneous Rayleigh-Taylor turbulence and Rayleigh-Taylor induced turbulence, as well as the inability to match both homogeneous shear and free shear flows. The two-length scale model focuses on separating the decay and transport length scales,more » as the two physical processes are generally different in inhomogeneous turbulence. This allows reasonable comparisons with statistics and spreading rates over such a wide range of turbulent flows using a common set of model coefficients. The specific canonical flows considered for calibrating the model include homogeneous shear, single-phase incompressible shear driven turbulence, variable density homogeneous Rayleigh-Taylor turbulence, Rayleigh-Taylor induced turbulence, and shocked isotropic turbulence. The second moment model shows to compare reasonably well with direct numerical simulations (DNS), experiments, and theory in most cases. The model was then applied to variable density shear layer and shock tube data and shows to be in reasonable agreement with DNS and experiments. Additionally, the importance of using DNS to calibrate and assess RANS type turbulence models is highlighted.« less

Nonlinear flow affects hydrodynamic forces and neutrophil adhesion rates in cone-plate viscometers.

PubMed Central

Shankaran, H; Neelamegham, S

2001-01-01

We present a theoretical and experimental analysis of the effects of nonlinear flow in a cone-plate viscometer. The analysis predicts that flow in the viscometer is a function of two parameters, the Reynolds number and the cone angle. Nonlinear flow occurs at high shear rates and causes spatial variations in wall shear stress, collision frequency, interparticle forces and attachment times within the viscometer. We examined the effect of these features on cellular adhesion kinetics. Based on recent data (Taylor, A. D., S. Neelamegham, J. D. Hellums, et al. 1996. Biophys. J. 71:3488-3500), we modeled neutrophil homotypic aggregation as a process that is integrin-limited at low shear and selectin-limited at high shear. Our calculations suggest that selectin and integrin on-rates lie in the order of 10(-2)-10(-4)/s. They also indicate that secondary flow causes positional variations in adhesion efficiency in the viscometer, and that the overall efficiency is dependent not only on the shear rate, but also the sample volume and the cone angle. Experiments performed with isolated neutrophils confirmed these predictions. In these experiments, enhancing secondary flow by increasing the sample volume from 100 to 1000 microl at 1500/s for a 2 degrees cone caused up to an approximately 45% drop in adhesion efficiency. Our results suggest that secondary flow may significantly influence cellular aggregation, platelet activation, and endothelial cell mechanotransduction measurements made in the viscometer over the range of conditions applied in typical biological studies. PMID:11371440

Direct Numerical Simulation of Surfactant-Stabilized Emulsions Morphology and Shear Viscosity in Starting Shear Flow

DOE Office of Scientific and Technical Information (OSTI.GOV)

Roar Skartlien; Espen Sollum; Andreas Akselsen

2012-07-01

A 3D lattice Boltzmann model for two-phase flow with amphiphilic surfactant was used to investigate the evolution of emulsion morphology and shear stress in starting shear flow. The interfacial contributions were analyzed for low and high volume fractions and varying surfactant activity. A transient viscoelastic contribution to the emulsion rheology under constant strain rate conditions was attributed to the interfacial stress. For droplet volume fractions below 0.3 and an average capillary number of about 0.25, highly elliptical droplets formed. Consistent with affine deformation models, gradual elongation of the droplets increased the shear stress at early times and reduced it atmore » later times. Lower interfacial tension with increased surfactant activity counterbalanced the effect of increased interfacial area, and the net shear stress did not change significantly. For higher volume fractions, co-continuous phases with a complex topology were formed. The surfactant decreased the interfacial shear stress due mainly to advection of surfactant to higher curvature areas. Our results are in qualitative agreement with experimental data for polymer blends in terms of transient interfacial stresses and limited enhancement of the emulsion viscosity at larger volume fractions where the phases are co-continuous.« less

Microfluidic perfusion culture chip providing different strengths of shear stress for analysis of vascular endothelial function.

PubMed

Hattori, Koji; Munehira, Yoichi; Kobayashi, Hideki; Satoh, Taku; Sugiura, Shinji; Kanamori, Toshiyuki

2014-09-01

We developed a microfluidic perfusion cell culture chip that provides three different shear stress strengths and a large cell culture area for the analysis of vascular endothelial functions. The microfluidic network was composed of shallow flow-control channels of three different depths and deep cell culture channels. The flow-control channels with high fluidic resistances created shear stress strengths ranging from 1.0 to 10.0 dyn/cm(2) in the cell culture channels. The large surface area of the culture channels enabled cultivation of a large number (approximately 6.0 × 10(5)) of cells. We cultured human umbilical vein endothelial cells (HUVECs) and evaluated the changes in cellular morphology and gene expression in response to applied shear stress. The HUVECs were aligned in the direction of flow when exposed to a shear stress of 10.0 dyn/cm(2). Compared with conditions of no shear stress, endothelial nitric oxide synthase mRNA expression increased by 50% and thrombomodulin mRNA expression increased by 8-fold under a shear stress of 9.5 dyn/cm(2). Copyright © 2014 The Society for Biotechnology, Japan. Published by Elsevier B.V. All rights reserved.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schaffner, D. A.; Carter, T. A.; Rossi, G. D.

Continuous control over azimuthal flow and shear in the edge of the Large Plasma Device (LAPD) [W. Gekelman et al., Rev. Sci. Instr. 62, 2875 (1991)] has been achieved using a biasable limiter. This flow control has allowed a careful study of the effect of flow shear on pressure-gradient-driven turbulence and particle transport in LAPD. The combination of externally controllable shear in a turbulent plasma along with the detailed spatial diagnostic capabilities on LAPD makes the experiment a useful testbed for validation of shear suppression models. Motivated by these models, power-law fits are made to the density and radial velocitymore » fluctuation amplitudes, particle flux, density-potential crossphase, and radial correlation length. The data show a break in the trend of these quantities when the shearing rate (γ{sub s}=∂V{sub θ}/∂r) is comparable to the turbulent decorrelation rate (1/τ{sub ac}). No one model captures the trends in the all turbulent quantities for all values of the shearing rate, but some models successfully match the trend in either the weak (γ{sub s}τ{sub ac}<1) or strong (γ{sub s}τ{sub ac}>1) shear limits.« less

Assessment of turbulent viscous stress using ICOSA 4D Flow MRI for prediction of hemodynamic blood damage

NASA Astrophysics Data System (ADS)

Ha, Hojin; Lantz, Jonas; Haraldsson, Henrik; Casas, Belen; Ziegler, Magnus; Karlsson, Matts; Saloner, David; Dyverfeldt, Petter; Ebbers, Tino

2016-12-01

Flow-induced blood damage plays an important role in determining the hemodynamic impact of abnormal blood flow, but quantifying of these effects, which are dominated by shear stresses in highly fluctuating turbulent flow, has not been feasible. This study evaluated the novel application of turbulence tensor measurements using simulated 4D Flow MRI data with six-directional velocity encoding for assessing hemodynamic stresses and corresponding blood damage index (BDI) in stenotic turbulent blood flow. The results showed that 4D Flow MRI underestimates the maximum principal shear stress of laminar viscous stress (PLVS), and overestimates the maximum principal shear stress of Reynolds stress (PRSS) with increasing voxel size. PLVS and PRSS were also overestimated by about 1.2 and 4.6 times at medium signal to noise ratio (SNR) = 20. In contrast, the square sum of the turbulent viscous shear stress (TVSS), which is used for blood damage index (BDI) estimation, was not severely affected by SNR and voxel size. The square sum of TVSS and the BDI at SNR >20 were underestimated by less than 1% and 10%, respectively. In conclusion, this study demonstrated the feasibility of 4D Flow MRI based quantification of TVSS and BDI which are closely linked to blood damage.

Fractal aspects of the flow and shear behaviour of free-flowable particle size fractions of pharmaceutical directly compressible excipient sorbitol.

PubMed

Hurychová, Hana; Lebedová, Václava; Šklubalová, Zdenka; Dzámová, Pavlína; Svěrák, Tomáš; Stoniš, Jan

Flowability of powder excipients is directly influenced by their size and shape although the granulometric influence of the flow and shear behaviour of particulate matter is not studied frequently. In this work, the influence of particle size on the mass flow rate through the orifice of a conical hopper, and the cohesion and flow function was studied for four free-flowable size fractions of sorbitol for direct compression in the range of 0.080-0.400 mm. The particles were granulometricaly characterized using an optical microscopy; a boundary fractal dimension of 1.066 was estimated for regular sorbitol particles. In the particle size range studied, a non-linear relationship between the mean particle size and the mass flow rate Q10 (g/s) was detected having amaximum at the 0.245mm fraction. The best flow properties of this fraction were verified with aJenike shear tester due to the highest value of flow function and the lowest value of the cohesion. The results of this work show the importance of the right choice of the excipient particle size to achieve the best flow behaviour of particulate material.Key words: flowability size fraction sorbitol for direct compaction Jenike shear tester fractal dimension.

The Sedimentation of Particles under Orthogonal Shear in Viscoelastic Fluids

NASA Astrophysics Data System (ADS)

Murch, William L.; Krishnan, Sreenath; Shaqfeh, Eric S. G.

2016-11-01

Many engineering applications, including oil and gas recovery, require the suspension of particles in viscoelastic fluids during fluid transport and processing. A topic of specific importance involves such particle suspensions experiencing an applied shear flow in a direction perpendicular to gravity (referred to as orthogonal shear). Previously, it has been shown that particle sedimentation coupled with an orthogonal shear flow can reduce the particle settling rate in elastic fluids. The underlying mechanism of this enhanced coupling drag is not fully understood, particularly at finite Weissenberg numbers. This talk examines the role of fluid elasticity on a single, non-Brownian, rigid sphere settling in orthogonal shear using experiments and numerical simulations. New experiments were performed in a Taylor-Couette flow cell using Boger fluids to study the coupling drag as a function of the shear and sedimentation Weissenberg numbers as well as particle confinement. The elastic effect was also studied with fully 3D simulations of flow past a rigid sphere, using the FENE-P constitutive model to describe the polymeric fluid rheology. These simulations show good agreement with the experiments and allow for further insight into the mechanism of elasticity-enhanced drag. This material is based upon work supported by the National Science Foundation Graduate Research Fellowship.

Investigation of blood flow rheology using second-grade viscoelastic model (Phan-Thien-Tanner) within carotid artery.

PubMed

Ramiar, Abas; Larimi, Morsal Momenti; Ranjbar, Ali Akbar

2017-01-01

Hemodynamic factors, such as Wall Shear Stress (WSS), play a substantial role in arterial diseases. In the larger arteries, such as the carotid artery, interaction between the vessel wall and blood flow affects the distribution of hemodynamic factors. The fluid is considered to be non-Newtonian, whose flow is governed by the equation of a second-grade viscoelastic fluid and the effects of viscoelastic on blood flow in carotid artery is investigated. Pulsatile flow studies were carried out in a 3D model of carotid artery. The governing equations were solved using finite volume C++ based on open source code, OpenFOAM. To describe blood flow, conservation of mass and momentum, a constitutive relation of simplified Phan-Thien-Tanner (sPTT), and appropriate relations were used to explain shear thinning behavior. The first recirculation was observed at t = 0.2 s, in deceleration phase. In the acceleration phase from t = 0.3 s to t = 0.5 s, vortex and recirculation sizes in bulb regions in both ECA and ICA gradually increased. As is observed in the line graphs based on extracted data from ICA, at t = 0.2 s, τyy is the maximum amount of wall shear stress and τxy the minimum one. The maximum shear stress occurred in the inner side of the main branch (inner side of ICA and ECA) because the velocity of blood flow in the inner side of the bulb region was maximum due to the created recirculation zone in the opposite side in this area. The rheology of blood flow and shear stress in various important parts (the area that are in higher rates of WSS such as bifurcation region and the regions after bulb areas in both branches, Line1-4 in Fig. 7) were also analyzed. The investigation of velocity stream line, velocity profile and shear stress in various sections of carotid artery showed that the maximum shear stress occurred in acceleration phase and in the bifurcation region between ECA and ICA which is due to velocity gradients and changes in thinning behavior of blood and increasing strain rate in Newtonian stress part.

[Application of ultrasound counter currentextraction in patent of traditional Chinese medicine].

PubMed

Miao, Yan-ni; Wu, Bin; Yue, Xue-lian

2015-07-01

The patent information of ultrasound countercurrent extraction used in traditional Chinese medicine was analyzed in this paper by the samples from Derwent World Patent Database (DWPI) and the Chinese Patent Abstracts Database (CNABS). The application of ultrasound countercurrent was discussed with the patent applicant,the amount of the annual distribution, and the pharmaceutical raw materials and other aspects. While the technical parameters published in the patent was deeply analyzed, such as material crushing, extraction solvent, extraction time and temperature, extraction equipment and ultrasonic frequency. Thought above research, various technical parameters of ultrasound countercurrent extraction used in traditional Chinese was summarize. The analysis conclusion of the paper can be used in discovering the technical advantages, optimizing extraction conditions, and providing a reference to extraction technological innovation of traditional Chinese medicine.

Impact of shear rate modulation on vascular function in humans

PubMed Central

Tinken, Toni M.; Thijssen, Dick H.J.; Hopkins, Nicola; Black, Mark A.; Dawson, Ellen A.; Minson, Christopher T.; Newcomer, Sean C.; Laughlin, M. Harold; Cable, N. Timothy; Green, Daniel J.

2010-01-01

Shear stress is an important stimulus to arterial adaptation in response to exercise and training in humans. We recently observed significant reverse arterial flow and shear during exercise and different antegrade/retrograde patterns of shear and flow in response to different types of exercise. The purpose of this study was to simultaneously examine flow mediated dilation (FMD), a largely nitric oxide mediated vasodilator response, in both brachial arteries of healthy young men before and after 30-minute interventions consisting of bilateral forearm heating, recumbent leg cycling and bilateral handgrip exercise. During each intervention, a cuff inflated to 60mmHg was placed on one arm to unilaterally manipulate the shear rate stimulus. In the non-cuffed arm, antegrade flow and shear increased similarly in response to each intervention (ANOVA; P<0.001, no interaction between interventions; P=0.71). Baseline FMD (4.6, 6.9 and 6.7%) increased similarly in response to heating, handgrip and cycling (8.1, 10.4 and 8.9%, ANOVA; P<0.001, no interaction; 0.89). In contrast, cuffed arm antegrade shear rate was lower than in the non-cuffed arm for all conditions (P<0.05) and the increase in FMD was abolished in this arm (4.7, 6.7 and 6.1%) (2-way ANOVA: all conditions interacted P<0.05). These results suggest that differences in the magnitude of antegrade shear rate transduce differences in endothelial vasodilator function in humans, a finding which may have relevance for the impact of different exercise interventions on vascular adaptation in humans. PMID:19546374

SPOT satellite mapping of Ice Stream B

NASA Technical Reports Server (NTRS)

Merry, Carolyn J.

1993-01-01

Numerous features of glaciological significance appear on two adjoining SPOT High Resolution Visible (HRV) images that cover the onset region of ice stream B. Many small-scale features, such as crevasses and drift plumes, have been previously observed in aerial photography. Subtle features, such as long flow traces that have not been mapped previously, are also clear in the satellite imagery. Newly discovered features include ladder-like runners and rungs within certain shear margins, flow traces that are parallel to ice flow, unusual crevasse patterns, and flow traces originating within shear margins. An objective of our work is to contribute to an understanding of the genesis of the features observed in satellite imagery. The genetic possibilities for flow traces, other lineations, bands of transverse crevasses, shear margins, mottles, and lumps and warps are described.

Wave models for turbulent free shear flows

NASA Technical Reports Server (NTRS)

Liou, W. W.; Morris, P. J.

1991-01-01

New predictive closure models for turbulent free shear flows are presented. They are based on an instability wave description of the dominant large scale structures in these flows using a quasi-linear theory. Three model were developed to study the structural dynamics of turbulent motions of different scales in free shear flows. The local characteristics of the large scale motions are described using linear theory. Their amplitude is determined from an energy integral analysis. The models were applied to the study of an incompressible free mixing layer. In all cases, predictions are made for the development of the mean flow field. In the last model, predictions of the time dependent motion of the large scale structure of the mixing region are made. The predictions show good agreement with experimental observations.

Cone Penetrometer Shear Strength Measurements of Sludge Waste in Tanks 241-AN-101 and 241-AN-106

DOE Office of Scientific and Technical Information (OSTI.GOV)

Follett, Jordan R.

2014-03-06

This document presents the resulting shear strength profiles for sludge waste in Tanks 241-AN-101 and 241-AN-106, as determined with a full-flow cone penetrometer. Full-flow penetrometer measurements indicate shear strength profiles that increase roughly uniformly with depth. For Tank 241-AN-101, the undrained shear strength was calculated to range from 500 Pa near the sludge surface to roughly 3,300 Pa at 15 inches above the tank bottom. For 241-AN-106, the undrained shear strength was calculated to range from 500 Pa near the sludge surface to roughly 5,000 Pa at 15 inches above the tank bottom.

Laminar flow in a recess of a hydrostatic bearing

NASA Technical Reports Server (NTRS)

San Andres, Luis A.; Velthuis, Johannes F. M.

1992-01-01

The flow in a recess of a hydrostatic journal bearing is studied in detail. The Navier-Stokes equations for the laminar flow of an incompressible liquid are solved numerically in a two-dimensional plane of a typical bearing recess. Pressure- and shear-induced flows, as well as a combination of these two flow conditions, are analyzed. Recess friction, pressure-ram effects at discontinuities in the flow region, and film entrance pressure loss effects are calculated. Entrance pressure loss coefficients over a forward-facing step are presented as functions of the mean flow Reynolds number for pure-pressure and shear-induced laminar flows.

Simulation and modelling of slip flow over surfaces grafted with polymer brushes and glycocalyx fibres

PubMed Central

Deng, Mingge; Li, Xuejin; Liang, Haojun; Caswell, Bruce; Karniadakis, George Em

2013-01-01

Fabrication of functionalized surfaces using polymer brushes is a relatively simple process and parallels the presence of glycocalyx filaments coating the luminal surface of our vasculature. In this paper, we perform atomistic-like simulations based on dissipative particle dynamics (DPD) to study both polymer brushes and glycocalyx filaments subject to shear flow, and we apply mean-field theory to extract useful scaling arguments on their response. For polymer brushes, a weak shear flow has no effect on the brush density profile or its height, while the slip length is independent of the shear rate and is of the order of the brush mesh size as a result of screening by hydrodynamic interactions. However, for strong shear flow, the polymer brush is penetrated deeper and is deformed, with a corresponding decrease of the brush height and an increase of the slip length. The transition from the weak to the strong shear regime can be described by a simple ‘blob’ argument, leading to the scaling γ̇0 ∝ σ3/2, where γ̇0 is the critical transition shear rate and σ is the grafting density. Furthermore, in the strong shear regime, we observe a cyclic dynamic motion of individual polymers, causing a reversal in the direction of surface flow. To study the glycocalyx layer, we first assume a homogeneous flow that ignores the discrete effects of blood cells, and we simulate microchannel flows at different flow rates. Surprisingly, we find that, at low Reynolds number, the slip length decreases with the mean flow velocity, unlike the behaviour of polymer brushes, for which the slip length remains constant under similar conditions. (The slip length and brush height are measured with respect to polymer mesh size and polymer contour length, respectively.) We also performed additional DPD simulations of blood flow in a tube with walls having a glycocalyx layer and with the deformable red blood cells modelled accurately at the spectrin level. In this case, a plasma cell-free layer is formed, with thickness more than three times the glycocalyx layer. We then find our scaling arguments based on the homogeneous flow assumption to be valid for this physiologically correct case as well. Taken together, our findings point to the opposing roles of conformational entropy and bending rigidity – dominant effects for the brush and glycocalyx, respectively – which, in turn, lead to different flow characteristics, despite the apparent similarity of the two systems. PMID:24353347

Equilibrium E × B Flows in Nonlinear Gyrofluid Flux-Tube Simulations

NASA Astrophysics Data System (ADS)

Beer, M. A.; Hammett, G. W.

2000-10-01

Comparisons of theory with experiment often indicate levels of sheared E × B flow large enough to significantly suppress turbulence, especially when local transport barriers are formed. We extend our previous simulations by including equilibrium scale sheared E × B flow directly, by introducing a coordinate transformation which shears the simulation domain with the equilibrium E × B flow, while preserving smooth statistical periodicity across the radial domain. This method was used linearly in our previous comparisons with JET [Beer, Budny, Challis, et al., EPS (1999)] and is now applied to nonlinear simulations. This method makes use of some tricks suggested for this problem by Dimits [Int. Conf. on Numerical Simulation of Plasmas (1994)] based on special properties of discrete Fourier transforms. A similar coordinate transformation was previously used successfully by Waltz, et al. [Phys. Plasmas 5, 1784 (1998)], and we confirm their finding that the turbulence is suppressed when the shearing rate, ω_E, is comparable to the maximum linear growth rate in the absence of sheared flow, γ_lin. This is often significantly different than the threshold for linear suppression. With this extension, our simulations are able to address transport barriers from a more rigorous footing. Of particular interest will be the investigation of the expansion or propagation of barriers, where E × B shear suppression is by definition at the marginal point. In addition, our formulation uses general magnetic geometry, so we can rigorously investigate various geometrical effects (e.g. hats, Δ', κ) on the threshold for suppression.

Role of zonal flow predator-prey oscillations in triggering the transition to H-mode confinement.

PubMed

Schmitz, L; Zeng, L; Rhodes, T L; Hillesheim, J C; Doyle, E J; Groebner, R J; Peebles, W A; Burrell, K H; Wang, G

2012-04-13

Direct evidence of zonal flow (ZF) predator-prey oscillations and the synergistic roles of ZF- and equilibrium E×B flow shear in triggering the low- to high-confinement (L- to H-mode) transition in the DIII-D tokamak is presented. Periodic turbulence suppression is first observed in a narrow layer at and just inside the separatrix when the shearing rate transiently exceeds the turbulence decorrelation rate. The final transition to H mode with sustained turbulence and transport reduction is controlled by equilibrium E×B shear due to the increasing ion pressure gradient.

The effect of non-Newtonian viscosity on the stability of the Blasius boundary layer

NASA Astrophysics Data System (ADS)

Griffiths, P. T.; Gallagher, M. T.; Stephen, S. O.

2016-07-01

We consider, for the first time, the stability of the non-Newtonian boundary layer flow over a flat plate. Shear-thinning and shear-thickening flows are modelled using a Carreau constitutive viscosity relationship. The boundary layer equations are solved in a self-similar fashion. A linear asymptotic stability analysis, that concerns the lower-branch structure of the neutral curve, is presented in the limit of large Reynolds number. It is shown that the lower-branch mode is destabilised and stabilised for shear-thinning and shear-thickening fluids, respectively. Favourable agreement is obtained between these asymptotic predictions and numerical results obtained from an equivalent Orr-Sommerfeld type analysis. Our results indicate that an increase in shear-thinning has the effect of significantly reducing the value of the critical Reynolds number, this suggests that the onset of instability will be significantly advanced in this case. This postulation, that shear-thinning destabilises the boundary layer flow, is further supported by our calculations regarding the development of the streamwise eigenfunctions and the relative magnitude of the temporal growth rates.

Mechanical Dissociation of Platelet Aggregates in Blood Stream

NASA Astrophysics Data System (ADS)

Hoore, Masoud; Fedosov, Dmitry A.; Gompper, Gerhard; Complex; Biological Fluids Group Team

2017-11-01

von Willebrand factor (VWF) and platelet aggregation is a key phenomenon in blood clotting. These aggregates form critically in high shear rates and dissolve reversibly in low shear rates. The emergence of a critical shear rate, beyond which aggregates form and below which they dissolve, has an interesting impact on aggregation in blood flow. As red blood cells (RBCs) migrate to the center of the vessel in blood flow, a RBC free layer (RBC-FL) is left close to the walls into which the platelets and VWFs are pushed back from the bulk flow. This margination process provides maximal VWF-platelet aggregation probability in the RBC-FL. Using mesoscale hydrodynamic simulations of aggregate dynamics in blood flow, it is shown that the aggregates form and grow in RBC-FL wherein shear rate is high for VWF stretching. By growing, the aggregates penetrate to the bulk flow and get under order of magnitude lower shear rates. Consequently, they dissolve and get back into the RBC-FL. This mechanical limitation for aggregates prohibits undesired thrombosis and vessel blockage by aggregates, while letting the VWFs and platelets to aggregate close to the walls where they are actually needed. The support by the DFG Research Unit FOR 1543 SHENC and CPU time Grant by the Julich Supercomputing Center are acknowledged.

Sensor for Boundary Shear Stress in Fluid Flow

NASA Technical Reports Server (NTRS)

Bao, Xiaoqi; Badescu, Mircea; Sherrit, Stewart; Bar-Cohen, Yoseph; Lih, Shyh-Shiuh; Chang, Zensheu; Trease, Brian P.; Kerenyi, Kornel; Widholm, Scott E.; Ostlund, Patrick N.

2012-01-01

The formation of scour patterns at bridge piers is driven by the forces at the boundary of the water flow. In most experimental scour studies, indirect processes have been applied to estimate the shear stress using measured velocity profiles. The estimations are based on theoretical models and associated assumptions. However, the turbulence flow fields and boundary layer in the pier-scour region are very complex and lead to low-fidelity results. In addition, available turbulence models cannot account accurately for the bed roughness effect. Direct measurement of the boundary shear stress, normal stress, and their fluctuations are attractive alternatives. However, most direct-measurement shear sensors are bulky in size or not compatible to fluid flow. A sensor has been developed that consists of a floating plate with folded beam support and an optical grid on the back, combined with a high-resolution optical position probe. The folded beam support makes the floating plate more flexible in the sensing direction within a small footprint, while maintaining high stiffness in the other directions. The floating plate converts the shear force to displacement, and the optical probe detects the plate s position with nanometer resolution by sensing the pattern of the diffraction field of the grid through a glass window. This configuration makes the sensor compatible with liquid flow applications.

Influence of Brownian motion on blood platelet flow behavior and adhesive dynamics near a planar wall.

PubMed

Mody, Nipa A; King, Michael R

2007-05-22

We used the platelet adhesive dynamics computational method to study the influence of Brownian motion of a platelet on its flow characteristics near a surface in the creeping flow regime. Two important characterizations were done in this regard: (1) quantification of the platelet's ability to contact the surface by virtue of the Brownian forces and torques acting on it, and (2) determination of the relative importance of Brownian motion in promoting surface encounters in the presence of shear flow. We determined the Peclet number for a platelet undergoing Brownian motion in shear flow, which could be expressed as a simple linear function of height of the platelet centroid, H from the surface Pe (platelet) = . (1.56H + 0.66) for H > 0.3 microm. Our results demonstrate that at timescales relevant to shear flow in blood Brownian motion plays an insignificant role in influencing platelet motion or creating further opportunities for platelet-surface contact. The platelet Peclet number at shear rates >100 s-1 is large enough (>200) to neglect platelet Brownian motion in computational modeling of flow in arteries and arterioles for most practical purposes even at very close distances from the surface. We also conducted adhesive dynamics simulations to determine the effects of platelet Brownian motion on GPIbalpha-vWF-A1 single-bond dissociation dynamics. Brownian motion was found to have little effect on bond lifetime and caused minimal bond stressing as bond rupture forces were calculated to be less than 0.005 pN. We conclude from our results that, for the case of platelet-shaped cells, Brownian motion is not expected to play an important role in influencing flow characteristics, platelet-surface contact frequency, and dissociative binding phenomena under flow at physiological shear rates (>50 s(-1)).

Post-failure characteristics of weathered soils in Korea: determination of rheological thresholds and debris flow mobility

NASA Astrophysics Data System (ADS)

Jeong, Sueng-Won; Fukuoka, Hiroshi; Im, Sang-June

2013-04-01

Landslides in Korea are mainly triggered by localized summer heavy rainfall. The water infiltration, wetting and fluidization process are the key roles in slope instability. Mechanically, a loss in soil strength of the soil at weakend layer takes place as a result of water infiltration. The transition from slides to flows can be defined by the variation in strength parameters. In the flowing stage with large volume of sediments, debris flow impact may be governed by the rheology of the failed mass. We performed the rheological tests using the ball-measuring and vane-inserted rheometer and examined a possible threshold of landslides on mudstone, weathered granitic and gneissic soils in the mountainous region of Korea. The materials examined exhibited the shear-thinning behavior, which is the viscosity decreases with increasing shear rates. There are positive relationships between liquidity index and rheological values (i.e., yield stress and viscosities). However, the difference in rheological properties is of significance for given shear rates. The effect of wall-slip in different geometries is emphasized. This work is also concerned with post-failure characteristics of rainfall-induced landslides that occur in Chuncheon, Miryang and Seoul debris flow occurrence in 2011. They are mainly composed of gneissic, sedimentary and gneissic weathered soils. The rheological properties is helpful to predict the mobilization of fine-laden debris flows. In the relationship between shear stress and shear rate, one of simplest rheological models, i.e., the ideal Bingham fluid model, is selected to examine the flow pattern and depositional features of debris flows. A comparison will be made for the debris flow occurence on weahtered soils in Korea.

Intracellular pH changes in human aortic smooth muscle cells in response to fluid shear stress

NASA Technical Reports Server (NTRS)

Stamatas, G. N.; Patrick, C. W. Jr; McIntire, L. V.

1997-01-01

The smooth muscle cell (SMC) layers of human arteries may be exposed to blood flow after endothelium denudation, for example, following balloon angioplasty treatment. These SMCs are also constantly subjected to pressure driven transmural fluid flow. Flow-induced shear stress can alter SMC growth and metabolism. Signal transduction mechanisms involved in these flow effects on SMCs are still poorly understood. In this work, the hypothesis that shear stress alters the intracellular pH (pHi) of SMC is examined. When exposed to venous and arterial levels of shear stress, human aortic smooth muscle cells (hASMC) undergo alkalinization. The alkalinization plateau persisted even after 20 min of cell exposure to flow. Addition of amiloride (10 micromoles) or its 5-(N-ethyl-N-isopropyl) analog (EIPA, 10 micromoles), both Na+/H+ exchanger inhibitors, attenuated intracellular alkalinization, suggesting the involvement of the Na+/H+ exchanger in this response. The same concentrations of these inhibitors did not show an effect on pHi of hASMCs in static culture. 4-Acetamido-4'-isothio-cyanatostilbene-2,2'-disulfonic acid (SITS, 1 mM), a Cl-/HCO3- exchange inhibitor, affected the pHi of hASMCs both in static and flow conditions. Our results suggest that flow may perturb the Na+/H+ exchanger leading to an alkalinization of hASMCs, a different response from the flow-induced acidification seen with endothelial cells at the same levels of shear stress. Understanding the flow-induced signal transduction pathways in the vascular cells is of great importance in the tissue engineering of vascular grafts. In the case of SMCs, the involvement of pHi changes in nitric oxide production and proliferation regulation highlights further the significance of such studies.

Elastic moduli of a Brownian colloidal glass former

NASA Astrophysics Data System (ADS)

Fritschi, S.; Fuchs, M.

2018-01-01

The static, dynamic and flow-dependent shear moduli of a binary mixture of Brownian hard disks are studied by an event-driven molecular dynamics simulation. Thereby, the emergence of rigidity close to the glass transition encoded in the static shear modulus G_∞ is accessed by three methods. Results from shear stress auto-correlation functions, elastic dispersion relations, and the elastic response to strain deformations upon the start-up of shear flow are compared. This enables one to sample the time-dependent shear modulus G(t) consistently over several decades in time. By that a very precise specification of the glass transition point and of G_∞ is feasible. Predictions by mode coupling theory of a finite shear modulus at the glass transition, of α-scaling in fluid states close to the transition, and of shear induced decay in yielding glass states are tested and broadly verified.

Steady flow on to a conveyor belt - Causal viscosity and shear shocks

NASA Technical Reports Server (NTRS)

Syer, D.; Narayan, Ramesh

1993-01-01

Some hydrodynamical consequences of the adoption of a causal theory of viscosity are explored. Causality is introduced into the theory by letting the coefficient of viscosity go to zero as the flow velocity approaches a designated propagation speed for viscous signals. Consideration is given to a model of viscosity which has a finite propagation speed of shear information, and it is shown that it produces two kinds of shear shock. A 'pure shear shock' corresponds to a transition from a superviscous to a subviscous state with no discontinuity in the velocity. A 'mixed shear shock' has a shear transition occurring at the same location as a normal adiabatic or radiative shock. A generalized version of the Rankine-Hugoniot conditions for mixed shear shocks is derived, and self-consistent numerical solutions to a model 2D problem in which an axisymmetric radially infalling stream encounters a spinning star are presented.