Sample records for countries numerous tests

  1. Mean reversion in the current account of forty-eight african countries: Evidence from the Panel SURADF test

    NASA Astrophysics Data System (ADS)

    Chu, Hsiao-Ping; Chang, Tsangyao; Chang, Hsu-Ling; Su, Chi-Wei; Yuan, Young

    2007-10-01

    Here, the Panel seemingly unrelated regressions augmented Dickey-Fuller test (SURADF) test, first introduced and advanced by Breuer et al. [Misleading inferences from panel unit-root tests with an illustration from purchasing power parity, Rev. Int. Econ. 9(3) (2001) 482-493], is used to investigate the mean-reverting behavior of the current account of 48 African countries during the 1980-2004 periods. The empirical results from numerous panel-based unit root tests, conducted earlier, indicated that the current account of each of these countries is stationary; however, when Breuer et al.'s (2001) Panel SURADF test is conducted, it is found that a unit root exists in the current account of 11 of the countries studied. These results have one extremely important policy implication for the 48 African countries studied: the current account deficit of most is sustainable, and thus signifying that those nations should have no incentive to default on their international debt.

  2. The Full Costs of Ballistic Missile Defense

    DTIC Science & Technology

    2003-01-01

    following words: “We assess that countries developing ballistic missiles would also develop various responses to US theater and national defenses. Russia...and China each have developed numerous countermeasures and probably are willing to sell the requisite technologies. • Many countries , such as North...penetration aids and countermeasures. • These countries could develop countermeasures based on these technologies by the time they flight test their missiles

  3. SELECTING RELEVANT TEST SPECIES FOR ECOLOGICAL RISK ASSESSMENTS FOR PESTICIDES

    EPA Science Inventory

    In many countries, numerous tests are required prior to chemical registration for the protection of human health and the environment from the unintended effects of chemical releases. The species used in these tests are quite often familiar to scientists, have an extensive histor...

  4. USING A GEOGRAPHIC INFORMATION SYSTEM TO IDENTIFY AREAS WITH POTENTIAL FOR OFF-TARGET PESTICIDE EXPOSURE

    EPA Science Inventory

    In many countries, numerous tests are required as part of the risk assessment process before chemical registration to protect human health and the environment from unintended effects of chemical releases. Most of these tests are not based on ecological or environmental relevance ...

  5. A GIS WEB MAPPING APPROACH FOR IDENTIFYING SPECIES AND LOCATIONS FOR ECOLOGICAL RISK ASSESSMENTS

    EPA Science Inventory

    In many countries, numerous tests are required prior to chemical registration for the protection of human health and the environment from the unintended effects of chemical releases. Currently, plant testing in the United States requires the use of ten species, selected because t...

  6. Uncertain future, non-numeric preferences, and the fertility transition: A case study of rural Mozambique

    PubMed Central

    Hayford, Sarah R.; Agadjanian, Victor

    2012-01-01

    In many high-fertility countries, and especially in sub-Saharan Africa, substantial proportions of women give non-numeric responses when asked about desired family size. Demographic transition theory has interpreted responses of “don’t know” or “up to God” as evidence of fatalistic attitudes toward childbearing. Alternatively, these responses can be understood as meaningful reactions to uncertainty about the future. Following this latter approach, we use data from rural Mozambique to test the hypothesis that non-numeric responses are more common when uncertainty about the future is greater. We expand on previous research linking child mortality and non-numeric fertility preferences by testing the predictive power of economic conditions, marital instability, and adult mortality. Results show that uncertainty related to adult and child mortality and to economic conditions predicts non-numeric responses, while marital stability is less strongly related. PMID:26430294

  7. Uncertain future, non-numeric preferences, and the fertility transition: A case study of rural Mozambique.

    PubMed

    Hayford, Sarah R; Agadjanian, Victor

    In many high-fertility countries, and especially in sub-Saharan Africa, substantial proportions of women give non-numeric responses when asked about desired family size. Demographic transition theory has interpreted responses of "don't know" or "up to God" as evidence of fatalistic attitudes toward childbearing. Alternatively, these responses can be understood as meaningful reactions to uncertainty about the future. Following this latter approach, we use data from rural Mozambique to test the hypothesis that non-numeric responses are more common when uncertainty about the future is greater. We expand on previous research linking child mortality and non-numeric fertility preferences by testing the predictive power of economic conditions, marital instability, and adult mortality. Results show that uncertainty related to adult and child mortality and to economic conditions predicts non-numeric responses, while marital stability is less strongly related.

  8. Investigative Operations: Use of Covert Testing to Identify Security Vulnerabilities and Fraud, Waste, and Abuse

    DTIC Science & Technology

    2007-11-14

    including evaluations of controls over radioactive materials and security at America’s borders, airport security , sales of sensitive and surplus...officers. The details of this March 2006 report are classified; however, TSA has authorized this limited discussion. Airport Security Testing Sale of...of covert security vulnerability testing of numerous airports across the country. During these covert tests, our investigators passed through airport

  9. An Exploration of the Effectiveness of a Language Proficiency Test for Student Mobility

    ERIC Educational Resources Information Center

    Ünver, Meral Melek; Sahin, Murat Dogan

    2017-01-01

    University education is characterized by the atmosphere and opportunities offered to students to help master new skills, develop existing ones, realize and accept cultural diversity, hence broaden their horizons. Compared to past, students now have numerous alternatives either in the university in their home country or abroad. According to the…

  10. A GIS APPROACH FOR IDENTIFYING SPECIES AND LOCATIONS AT RISK FROM OFF-TARGET MOVEMENT OF PESTICIDES

    EPA Science Inventory

    In many countries, numerous tests are required prior to pesticide registration for the protection of human health and the environment from the unintended effects of chemical releases. Current methodology used by the US EPA for determining plant species at risk from off site movem...

  11. Food category consumption and obesity prevalence across countries: an application of Machine Learning method to big data analysis

    NASA Astrophysics Data System (ADS)

    Dunstan, Jocelyn; Fallah-Fini, Saeideh; Nau, Claudia; Glass, Thomas; Global Obesity Prevention Center Team

    The applications of sophisticated mathematical and numerical tools in public health has been demonstrated to be useful in predicting the outcome of public intervention as well as to study, for example, the main causes of obesity without doing experiments with the population. In this project we aim to understand which kind of food consumed in different countries over time best defines the rate of obesity in those countries. The use of Machine Learning is particularly useful because we do not need to create a hypothesis and test it with the data, but instead we learn from the data to find the groups of food that best describe the prevalence of obesity.

  12. Parenting Practices Scale: Its Validity and Reliability for Parents of School-Aged Children

    ERIC Educational Resources Information Center

    Kahraman, Hanife; Yilmaz Irmak, Turkan; Basokcu, T. Oguz

    2017-01-01

    Parenting practices are a field in psychology in which numerous studies have been carried out. In western countries, attempts to define the concept operationally have led to the emergence of many scales claiming to test the concept. This study aims at developing a scale to evaluate the parenting practices of parents with schoolchildren and at…

  13. Numerical modelling as a cost-reduction tool for probability of detection of bolt hole eddy current testing

    NASA Astrophysics Data System (ADS)

    Mandache, C.; Khan, M.; Fahr, A.; Yanishevsky, M.

    2011-03-01

    Probability of detection (PoD) studies are broadly used to determine the reliability of specific nondestructive inspection procedures, as well as to provide data for damage tolerance life estimations and calculation of inspection intervals for critical components. They require inspections on a large set of samples, a fact that makes these statistical assessments time- and cost-consuming. Physics-based numerical simulations of nondestructive testing inspections could be used as a cost-effective alternative to empirical investigations. They realistically predict the inspection outputs as functions of the input characteristics related to the test piece, transducer and instrument settings, which are subsequently used to partially substitute and/or complement inspection data in PoD analysis. This work focuses on the numerical modelling aspects of eddy current testing for the bolt hole inspections of wing box structures typical of the Lockheed Martin C-130 Hercules and P-3 Orion aircraft, found in the air force inventory of many countries. Boundary element-based numerical modelling software was employed to predict the eddy current signal responses when varying inspection parameters related to probe characteristics, crack geometry and test piece properties. Two demonstrator exercises were used for eddy current signal prediction when lowering the driver probe frequency and changing the material's electrical conductivity, followed by subsequent discussions and examination of the implications on using simulated data in the PoD analysis. Despite some simplifying assumptions, the modelled eddy current signals were found to provide similar results to the actual inspections. It is concluded that physics-based numerical simulations have the potential to partially substitute or complement inspection data required for PoD studies, reducing the cost, time, effort and resources necessary for a full empirical PoD assessment.

  14. Improving laboratory efficiencies to scale-up HIV viral load testing.

    PubMed

    Alemnji, George; Onyebujoh, Philip; Nkengasong, John N

    2017-03-01

    Viral load measurement is a key indicator that determines patients' response to treatment and risk for disease progression. Efforts are ongoing in different countries to scale-up access to viral load testing to meet the Joint United Nations Programme on HIV and AIDS target of achieving 90% viral suppression among HIV-infected patients receiving antiretroviral therapy. However, the impact of these initiatives may be challenged by increased inefficiencies along the viral load testing spectrum. This will translate to increased costs and ineffectiveness of scale-up approaches. This review describes different parameters that could be addressed across the viral load testing spectrum aimed at improving efficiencies and utilizing test results for patient management. Though progress is being made in some countries to scale-up viral load, many others still face numerous challenges that may affect scale-up efficiencies: weak demand creation, ineffective supply chain management systems; poor specimen referral systems; inadequate data and quality management systems; and weak laboratory-clinical interface leading to diminished uptake of test results. In scaling up access to viral load testing, there should be a renewed focus to address efficiencies across the entire spectrum, including factors related to access, uptake, and impact of test results.

  15. Hybrid finite volume-finite element model for the numerical analysis of furrow irrigation and fertigation

    USDA-ARS?s Scientific Manuscript database

    Although slowly abandoned in developed countries, furrow irrigation systems continue to be a dominant irrigation method in developing countries. Numerical models represent powerful tools to assess irrigation and fertigation efficiency. While several models have been proposed in the past, the develop...

  16. The demography of words: The global decline in non-numeric fertility preferences, 1993-2011.

    PubMed

    Frye, Margaret; Bachan, Lauren

    2017-07-01

    This paper examines the decline in non-numeric responses to questions about fertility preferences among women in the developing world. These types of response-such as 'don't know' or 'it's up to God'-have often been interpreted through the lens of fertility transition theory as an indication that reproduction has not yet entered women's 'calculus of conscious choice'. However, this has yet to be investigated cross-nationally and over time. Using 19 years of data from 32 countries, we find that non-numeric fertility preferences decline most substantially in the early stages of a country's fertility transition. Using country-specific and multilevel models, we explore the individual- and contextual-level characteristics associated with women's likelihood of providing a non-numeric response to questions about their fertility preferences. Non-numeric fertility preferences are influenced by a host of social factors, with educational attainment and knowledge of contraception being the most robust and consistent predictors.

  17. Animal alternatives for whole effluent toxicity testing ...

    EPA Pesticide Factsheets

    Since the 1940s, effluent toxicity testing has been utilized to varying degrees in many countries to assess potential ecological impacts and assist in determining necessary treatment options for environmental protection. However, it was only in the early 1980’s that toxicity based effluent assessments and subsequent discharge controls became globally important, when it was recognized that physical and chemical measurements alone did not protect the environment from potential impacts. Consequently, various strategies using different toxicity tests, whole effluent assessment techniques (incorporating bioaccumulation potential and persistence) plus supporting analytical tools have been developed over 30 years of practice. Numerous workshops and meetings have focused on effluent risk assessment through ASTM, SETAC, OSPAR, UK competent authorities, and EU specific country rules. Concurrent with this drive to improve effluent quality using toxicity tests, interest in reducing animal use has risen. The Health and Environmental Sciences Institute (HESI) organized and facilitated an international workshop in March 2016 to evaluate strategies for concepts, tools, and effluent assessments and update the toolbox of for effluent testing methods. The workshop objectives were to identify opportunities to use a suite of strategies for effluents, and to identify opportunities to reduce the reliance on animal tests and to determine barriers to implementation of new methodologie

  18. Physics League Across Numerous Countries for Kick-ass Students (PLANCKS)

    NASA Astrophysics Data System (ADS)

    Haasnoot, Irene

    2016-01-01

    Physics League Across Numerous Countries for Kick-ass Students (PLANCKS) is an international theoretical physics competition for bachelor and master students. The intention of PLANCKS is to increase international collaboration and stimulate the personal development of individual contestants. This is done by organizing a three-day-event which take place every year and is hosted by different countries. Besides the contest, social and scientific activities will be organised, including an opening symposium where leading physicists give lectures to inspire the participants.

  19. An Approach to Identify and Characterize a Subunit Candidate Shigella Vaccine Antigen.

    PubMed

    Pore, Debasis; Chakrabarti, Manoj K

    2016-01-01

    Shigellosis remains a serious issue throughout the developing countries, particularly in children under the age of 5. Numerous strategies have been tested to develop vaccines targeting shigellosis; unfortunately despite several years of extensive research, no safe, effective, and inexpensive vaccine against shigellosis is available so far. Here, we illustrate in detail an approach to identify and establish immunogenic outer membrane proteins from Shigella flexneri 2a as subunit vaccine candidates.

  20. Testing Hypotheses on Risk Factors for Scientific Misconduct via Matched-Control Analysis of Papers Containing Problematic Image Duplications.

    PubMed

    Fanelli, Daniele; Costas, Rodrigo; Fang, Ferric C; Casadevall, Arturo; Bik, Elisabeth M

    2018-02-19

    It is commonly hypothesized that scientists are more likely to engage in data falsification and fabrication when they are subject to pressures to publish, when they are not restrained by forms of social control, when they work in countries lacking policies to tackle scientific misconduct, and when they are male. Evidence to test these hypotheses, however, is inconclusive due to the difficulties of obtaining unbiased data. Here we report a pre-registered test of these four hypotheses, conducted on papers that were identified in a previous study as containing problematic image duplications through a systematic screening of the journal PLoS ONE. Image duplications were classified into three categories based on their complexity, with category 1 being most likely to reflect unintentional error and category 3 being most likely to reflect intentional fabrication. We tested multiple parameters connected to the hypotheses above with a matched-control paradigm, by collecting two controls for each paper containing duplications. Category 1 duplications were mostly not associated with any of the parameters tested, as was predicted based on the assumption that these duplications were mostly not due to misconduct. Categories 2 and 3, however, exhibited numerous statistically significant associations. Results of univariable and multivariable analyses support the hypotheses that academic culture, peer control, cash-based publication incentives and national misconduct policies might affect scientific integrity. No clear support was found for the "pressures to publish" hypothesis. Female authors were found to be equally likely to publish duplicated images compared to males. Country-level parameters generally exhibited stronger effects than individual-level parameters, because developing countries were significantly more likely to produce problematic image duplications. This suggests that promoting good research practices in all countries should be a priority for the international research integrity agenda.

  1. Justifying gender discrimination in the workplace: The mediating role of motherhood myths.

    PubMed

    Verniers, Catherine; Vala, Jorge

    2018-01-01

    The issue of gender equality in employment has given rise to numerous policies in advanced industrial countries, all aimed at tackling gender discrimination regarding recruitment, salary and promotion. Yet gender inequalities in the workplace persist. The purpose of this research is to document the psychosocial process involved in the persistence of gender discrimination against working women. Drawing on the literature on the justification of discrimination, we hypothesized that the myths according to which women's work threatens children and family life mediates the relationship between sexism and opposition to a mother's career. We tested this hypothesis using the Family and Changing Gender Roles module of the International Social Survey Programme. The dataset contained data collected in 1994 and 2012 from 51632 respondents from 18 countries. Structural equation modellings confirmed the hypothesised mediation. Overall, the findings shed light on how motherhood myths justify the gender structure in countries promoting gender equality.

  2. Justifying gender discrimination in the workplace: The mediating role of motherhood myths

    PubMed Central

    2018-01-01

    The issue of gender equality in employment has given rise to numerous policies in advanced industrial countries, all aimed at tackling gender discrimination regarding recruitment, salary and promotion. Yet gender inequalities in the workplace persist. The purpose of this research is to document the psychosocial process involved in the persistence of gender discrimination against working women. Drawing on the literature on the justification of discrimination, we hypothesized that the myths according to which women’s work threatens children and family life mediates the relationship between sexism and opposition to a mother’s career. We tested this hypothesis using the Family and Changing Gender Roles module of the International Social Survey Programme. The dataset contained data collected in 1994 and 2012 from 51632 respondents from 18 countries. Structural equation modellings confirmed the hypothesised mediation. Overall, the findings shed light on how motherhood myths justify the gender structure in countries promoting gender equality. PMID:29315326

  3. An overview assessment of the effectiveness and global popularity of some methods used in measuring riverbank filtration

    NASA Astrophysics Data System (ADS)

    Umar, Da'u. Abba; Ramli, Mohammad Firuz; Aris, Ahmad Zaharin; Sulaiman, Wan Nor Azmin; Kura, Nura Umar; Tukur, Abubakar Ibrahim

    2017-07-01

    This paper presents an overview assessment of the effectiveness and popularity of some methods adopted in measuring river bank filtration (RBF). The review is aim at understanding some of the appropriate methods used in measuring riverbank filtration, their frequencies of use, and their spatial applications worldwide. The most commonly used methods and techniques in riverbank filtration studies are: Geographical Information System (GIS) (site suitability/surface characterization), Geophysical, Pumping Test and borehole logging (sub-surface), Hydrochemical, Geochemical, and Statistical techniques (hydrochemistry of water), Numerical modelling, Tracer techniques and Stable Isotope Approaches (degradation and contaminants attenuation processes). From the summary in Table 1, hydrochemical, numerical modelling and pumping test are the frequently used and popular methods, while geophysical, GIS and statistical techniques are the less attractive. However, many researchers prefer integrated approach especially that riverbank filtration studies involve diverse and interrelated components. In term of spatial popularity and successful implementation of riverbank filtration, it is explicitly clear that the popularity and success of the technology is more pronounced in developed countries like U.S. and most European countries. However, it is gradually gaining ground in Asia and Africa, although it is not far from its infancy state in Africa, where the technology could be more important considering the economic status of the region and its peculiarity when it comes to water resources predicaments.

  4. Using routine health information systems for well-designed health evaluations in low- and middle-income countries

    PubMed Central

    Wagenaar, Bradley H; Sherr, Kenneth; Fernandes, Quinhas; Wagenaar, Alexander C

    2016-01-01

    Routine health information systems (RHISs) are in place in nearly every country and provide routinely collected full-coverage records on all levels of health system service delivery. However, these rich sources of data are regularly overlooked for evaluating causal effects of health programmes due to concerns regarding completeness, timeliness, representativeness and accuracy. Using Mozambique’s national RHIS (Módulo Básico) as an illustrative example, we urge renewed attention to the use of RHIS data for health evaluations. Interventions to improve data quality exist and have been tested in low-and middle-income countries (LMICs). Intrinsic features of RHIS data (numerous repeated observations over extended periods of time, full coverage of health facilities, and numerous real-time indicators of service coverage and utilization) provide for very robust quasi-experimental designs, such as controlled interrupted time-series (cITS), which are not possible with intermittent community sample surveys. In addition, cITS analyses are well suited for continuously evolving development contexts in LMICs by: (1) allowing for measurement and controlling for trends and other patterns before, during and after intervention implementation; (2) facilitating the use of numerous simultaneous control groups and non-equivalent dependent variables at multiple nested levels to increase validity and strength of causal inference; and (3) allowing the integration of continuous ‘effective dose received’ implementation measures. With expanded use of RHIS data for the evaluation of health programmes, investments in data systems, health worker interest in and utilization of RHIS data, as well as data quality will further increase over time. Because RHIS data are ministry-owned and operated, relying upon these data will contribute to sustainable national capacity over time. PMID:25887561

  5. Using routine health information systems for well-designed health evaluations in low- and middle-income countries.

    PubMed

    Wagenaar, Bradley H; Sherr, Kenneth; Fernandes, Quinhas; Wagenaar, Alexander C

    2016-02-01

    Routine health information systems (RHISs) are in place in nearly every country and provide routinely collected full-coverage records on all levels of health system service delivery. However, these rich sources of data are regularly overlooked for evaluating causal effects of health programmes due to concerns regarding completeness, timeliness, representativeness and accuracy. Using Mozambique's national RHIS (Módulo Básico) as an illustrative example, we urge renewed attention to the use of RHIS data for health evaluations. Interventions to improve data quality exist and have been tested in low-and middle-income countries (LMICs). Intrinsic features of RHIS data (numerous repeated observations over extended periods of time, full coverage of health facilities, and numerous real-time indicators of service coverage and utilization) provide for very robust quasi-experimental designs, such as controlled interrupted time-series (cITS), which are not possible with intermittent community sample surveys. In addition, cITS analyses are well suited for continuously evolving development contexts in LMICs by: (1) allowing for measurement and controlling for trends and other patterns before, during and after intervention implementation; (2) facilitating the use of numerous simultaneous control groups and non-equivalent dependent variables at multiple nested levels to increase validity and strength of causal inference; and (3) allowing the integration of continuous 'effective dose received' implementation measures. With expanded use of RHIS data for the evaluation of health programmes, investments in data systems, health worker interest in and utilization of RHIS data, as well as data quality will further increase over time. Because RHIS data are ministry-owned and operated, relying upon these data will contribute to sustainable national capacity over time. © The Author 2015. Published by Oxford University Press in association with The London School of Hygiene and Tropical Medicine.

  6. Mammographic image quality in relation to positioning of the breast: A multicentre international evaluation of the assessment systems currently used, to provide an evidence base for establishing a standardised method of assessment.

    PubMed

    Taylor, K; Parashar, D; Bouverat, G; Poulos, A; Gullien, R; Stewart, E; Aarre, R; Crystal, P; Wallis, M

    2017-11-01

    Optimum mammography positioning technique is necessary to maximise cancer detection. Current criteria for mammography appraisal lack reliability and validity with a need to develop a more objective system. We aimed to establish current international practice in assessing image quality (IQ), of screening mammograms then develop and validate a reproducible assessment tool. A questionnaire sent to centres in countries undertaking population screening identified practice, participants for an expert panel (EP) of radiologists/radiographers and a testing panel (TP) of radiographers. The EP developed category criteria and descriptors using a modified Delphi process to agree definitions. The EP scored 12 screening mammograms to test agreement then a main set of 178 cases. Weighted scores were derived for each descriptor enabling calculation of numerical parameters for each new category. The TP then scored the main set. Statistical analysis included ANOVA, t-tests and Kendall's coefficient. 11 centres in 8 countries responded forming an EP of 7 members and TP of 44 members. The EP showed moderate agreement when the scoring the mini test set W = 0.50 p < 0.001 and the main set W = 0.55 p < 0.001, 'posterior nipple line' being the most difficult descriptor. The weighted total scores differentiated the 4 new categories Perfect, Good, Adequate and Inadequate (p < 0.001). We have developed an assessment tool by Delphi consensus and weighted consensus criteria. We have successfully tabulated a range of numerical scores for each new category providing the first validated and reproducible mammography IQ scoring system. Copyright © 2017 The College of Radiographers. Published by Elsevier Ltd. All rights reserved.

  7. 26 CFR 7.999-1 - Computation of the international boycott factor.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... country, (iii) Securities by a dealer to a beneficial owner that is a resident of that country (but only... country, (iv) Intangible property (other than securities) in that country, (v) Securities by a dealer to a... numerator by reason of this subparagraph. (8) Payroll paid or accrued for services performed in a country...

  8. [Introduction of vaccination against human papillomavirus in developing countries: update and perspectives].

    PubMed

    Hessel, L

    2009-08-01

    Cervical cancer and other diseases related to human papillomavirus (HPV) represent a global public health problem. Safe and effective vaccines are now available and already used in many industrialized countries. Immunization offers the best hope for protecting the population against a disease that is the second most deadly cancer in the developing world and the first most deadly in Africa. The World Health Organization currently recommends introduction of HVP vaccination in developing countries. Widespread vaccination could be beneficial in numerous domains other than primary prevention of cervical cancer. Efforts to overcome the numerous obstacles and speed up implementation of HVP vaccination programs are now underway in many areas ranging from related scientific issues such as epidemiology and clinical research to administrative concerns such as healthcare economics, vaccination guidelines, public acceptation, program funding, and universal access. Vaccine manufacturers have committed themselves to working in partnership with national and international organizations to ensure access to HPV vaccine for all countries regardless of economic level, Although numerous issues must be resolved to optimize the use of HPV vaccines and ensure synergistic integration of vaccination, screening and treatment, current initiatives and efforts should allow introduction of HPV vaccination in developing countries in a not too distant future.

  9. Is viscoelastic coagulation monitoring with ROTEM or TEG validated?

    PubMed

    Solomon, Cristina; Asmis, Lars M; Spahn, Donat R

    2016-10-01

    Recent years have seen increasing worldwide interest in the use of viscoelastic coagulation monitoring tests, performed using devices such as ROTEM and TEG. The use of such tests to guide haemostatic therapy may help reduce transfusion of allogeneic blood products in bleeding patients and is supported in European guidelines for managing trauma and severe perioperative bleeding. In addition, viscoelastic tests form the basis of numerous published treatment algorithms. However, some publications have stated that viscoelastic tests are not validated. A specific definition of the term validation is lacking and regulatory requirements of the US Food and Drug Administration (FDA) and European Medicines Agency (EMA) have been fulfilled by ROTEM and TEG assays. Viscoelastic tests have been used in pivotal clinical trials, and they are approved for use in most of the world's countries. Provided that locally approved indications are adhered to, the regulatory framework for clinicians to use viscoelastic tests in routine clinical practice is in place.

  10. Optimal Asset Distribution for Environmental Assessment and Forecasting Based on Observations, Adaptive Sampling, and Numerical Prediction

    DTIC Science & Technology

    2012-09-30

    and Forecasting Based on Observations, Adaptive Sampling, and Numerical Prediction Steven R. Ramp Soliton Ocean Services, Inc. 691 Country Club... Soliton Ocean Services, Inc,691 Country Club Drive,Monterey,CA,93924 8. PERFORMING ORGANIZATION REPORT NUMBER 9. SPONSORING/MONITORING AGENCY NAME(S...shortwave. The results show that the incoming shortwave radiation was the dominant term, even when averaged over the dark hours, which accounts

  11. Politics, Violence, and Education: Other People's Countries.

    ERIC Educational Resources Information Center

    Christodoulou, Niki

    This paper's purpose is to illustrate, through the author's personal experiences, that violent actions occur in the world that affect people, countries, and relations in multiple levels and numerous ways. Using autobiographical inquiry, the author narrates how she experienced violence in three different countries in which she has lived. In Cyprus,…

  12. Work Environment-Related Risk Factors for Leptospirosis among Plantation Workers in Tropical Countries: Evidence from Malaysia.

    PubMed

    Mohd Ridzuan, J; Aziah, B D; Zahiruddin, W M

    2016-07-01

    Leptospirosis is a zoonotic disease that is recognized as a re-emerging global public health issue, especially in tropical and subtropical countries. Malaysia, for example, has increasingly registered leptospirosis cases, outbreaks, and fatalities over the past decade. One of the major industries in the country is the palm oil sector, which employs numerous agricultural workers. These laborers are at a particularly high risk of contracting the disease. To identify the work environment-related risk factors for leptospirosis infection among oil palm plantation workers in Malaysia. A cross-sectional study involving 350 workers was conducted. The participants were interviewed and administered a microscopic agglutination test. Seropositivity was determined using a cut-off titer of ≥1:100. 100 of 350 workers tested positive for leptospiral antibodies, hence, a seroprevalence of 28.6% (95% CI 23.8% to 33.3%). The workplace environment-related risk factors significantly associated with seropositive leptospirosis were the presence of cows in plantations (adjusted OR 4.78, 95% CI 2.76 to 8.26) and the presence of a landfill in plantations (adjusted OR 2.04, 95% CI 1.22 to 3.40). Preventing leptospirosis incidence among oil palm plantation workers necessitates changes in policy on work environments. Identifying modifiable factors may also contribute to the reduction of the infection.

  13. Teaching English as a "Second Language" in Kenya and the United States: Convergences and Divergences

    ERIC Educational Resources Information Center

    Roy-Campbell, Zaline M.

    2015-01-01

    English is spoken in five countries as the native language and in numerous other countries as an official language and the language of instruction. In countries where English is the native language, it is taught to speakers of other languages as an additional language to enable them to participate in all domains of life of that country. In many…

  14. A mixed-methods study of health worker migration from Jamaica.

    PubMed

    Tomblin Murphy, Gail; MacKenzie, Adrian; Waysome, Benjamin; Guy-Walker, Joan; Palmer, Rowena; Elliott Rose, Annette; Rigby, Janet; Labonté, Ronald; Bourgeault, Ivy Lynn

    2016-06-30

    This study sought to better understand the drivers of migration, its consequences, and the various strategies countries have employed to mitigate its negative impacts. The study was conducted in four countries-Jamaica, India, the Philippines, and South Africa-that have historically been 'sources' of health workers migrating to other countries. The aim of this paper is to present the findings from the Jamaica portion of the study. Data were collected using surveys of Jamaica's generalist and specialist physicians, nurses, midwives, and dental auxiliaries, as well as structured interviews with key informants representing government ministries, professional associations, regional health authorities, healthcare facilities, and educational institutions. Quantitative data were analyzed using descriptive statistics and regression models. Qualitative data were analyzed thematically. Multiple stakeholder engagement workshops were held across Jamaica to share and validate the study findings and discuss implications for the country. Migration of health workers from Jamaica continues to be prevalent. Its causes are numerous, long-standing, and systemic, and are largely based around differences in living and working conditions between Jamaica and 'destination' countries. There is minimal formal tracking of health worker migration from Jamaica, making scientific analysis of its consequences difficult. Although there is evidence of numerous national and international efforts to manage and mitigate the negative impacts of migration, there is little evidence of the implementation or effectiveness of such efforts. Potential additional strategies for better managing the migration of Jamaica's health workers include the use of information systems to formally monitor migration, updating the national cadre system for employment of health personnel, ensuring existing personnel management policies, such as bonding, are both clearly understood and equitably enforced, and providing greater formal and informal recognition of health personnel. Although historically common, migration of Jamaica's health workers is poorly monitored and understood. Improved management of the migration of Jamaica's health workers requires collaboration from stakeholders across multiple sectors. Indeed, participating stakeholders identified a wide range of potential strategies to better manage migration of Jamaica's health workers, the implementation and testing of which will have potential benefits to Jamaica as well as other 'source' countries.

  15. Microbiological diagnosis of human papilloma virus infection.

    PubMed

    Mateos-Lindemann, Maria Luisa; Pérez-Castro, Sonia; Rodríguez-Iglesias, Manuel; Pérez-Gracia, Maria Teresa

    2017-11-01

    Infection with human papillomavirus (HPV) is the leading cause of sexually transmitted infection worldwide. This virus generally causes benign lesions, such as genital warts, but persistent infection may lead to cervical cancer, anal cancer, vaginal cancer, and oropharyngeal cancer, although less frequently. Cervical cancer is a severe disease with a high mortality in some countries. Screening with cytology has been very successful in the last few years, but nowadays there are numerous studies that confirm that cytology should be replaced with the detection of HPV as a first line test in population based screening. There are several commercially available FDA approved tests for screening of cervical cancer. A new strategy, based on individual detection of the high risk genotypes HPV16 and HPV18, present in 70% of cervical cancer biopsies, has been proposed by some experts, and is going to be implemented in most countries in the future. Copyright © 2016 Elsevier España, S.L.U. and Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica. All rights reserved.

  16. Dangerous compounds in the dredged material from the sea - Assessment of the current approach to the evaluation of contaminations based on the data from the Polish coastal zone (the Baltic Sea).

    PubMed

    Staniszewska, Marta; Boniecka, Helena

    2018-05-01

    It has been shown that the current approach to the assessment of contamination in the sediments obtained during the dredging works in the Baltic countries indicates the presence of "non-contaminated" dredged material. The concentration limits of heavy metals, Polycyclic Aromatic Hydrocarbons (PAHs), Polychlorinated Biphenyls (PCBs) have been exceeded only in 1% of the samples obtained during the dredging works (2005-2015) within the Polish coastal zone. After 2008, no contaminated sediments have been found. Also, in the remaining Baltic countries, sediments are very rarely contaminated. As a result of this assessment, the sediments can be stored in the sea or have a practical application. However, it has been questioned whether the large cost of determining the numerous chemical parameters is justified. It has been proposed to carry out simple screening tests. Following the preliminary screening, the decision on more detailed (and expensive) chemical tests of individual pollutants would be made. Copyright © 2018 Elsevier Ltd. All rights reserved.

  17. Results from early programmatic implementation of Xpert MTB/RIF testing in nine countries.

    PubMed

    Creswell, Jacob; Codlin, Andrew J; Andre, Emmanuel; Micek, Mark A; Bedru, Ahmed; Carter, E Jane; Yadav, Rajendra-Prasad; Mosneaga, Andrei; Rai, Bishwa; Banu, Sayera; Brouwer, Miranda; Blok, Lucie; Sahu, Suvanand; Ditiu, Lucica

    2014-01-02

    The Xpert MTB/RIF assay has garnered significant interest as a sensitive and rapid diagnostic tool to improve detection of sensitive and drug resistant tuberculosis. However, most existing literature has described the performance of MTB/RIF testing only in study conditions; little information is available on its use in routine case finding. TB REACH is a multi-country initiative focusing on innovative ways to improve case notification. We selected a convenience sample of nine TB REACH projects for inclusion to cover a range of implementers, regions and approaches. Standard quarterly reports and machine data from the first 12 months of MTB/RIF implementation in each project were utilized to analyze patient yields, rifampicin resistance, and failed tests. Data was collected from September 2011 to March 2013. A questionnaire was implemented and semi-structured interviews with project staff were conducted to gather information on user experiences and challenges. All projects used MTB/RIF testing for people with suspected TB, as opposed to testing for drug resistance among already diagnosed patients. The projects placed 65 machines (196 modules) in a variety of facilities and employed numerous case-finding strategies and testing algorithms. The projects consumed 47,973 MTB/RIF tests. Of valid tests, 7,195 (16.8%) were positive for MTB. A total of 982 rifampicin resistant results were found (13.6% of positive tests). Of all tests conducted, 10.6% failed. The need for continuous power supply was noted by all projects and most used locally procured solutions. There was considerable heterogeneity in how results were reported and recorded, reflecting the lack of standardized guidance in some countries. The findings of this study begin to fill the gaps among guidelines, research findings, and real-world implementation of MTB/RIF testing. Testing with Xpert MTB/RIF detected a large number of people with TB that routine services failed to detect. The study demonstrates the versatility and impact of the technology, but also outlines various surmountable barriers to implementation. The study is not representative of all early implementer experiences with MTB/RIF testing but rather provides an overview of the shared issues as well as the many different approaches to programmatic MTB/RIF implementation.

  18. Genetic diversity of Plasmodium falciparum histidine-rich protein 2 (PfHRP2) and its effect on the performance of PfHRP2-based rapid diagnostic tests.

    PubMed

    Baker, Joanne; McCarthy, James; Gatton, Michelle; Kyle, Dennis E; Belizario, Vicente; Luchavez, Jennifer; Bell, David; Cheng, Qin

    2005-09-01

    Rising costs of antimalarial agents are increasing the demand for accurate diagnosis of malaria. Rapid diagnostic tests (RDTs) offer great potential to improve the diagnosis of malaria, particularly in remote areas. Many RDTs are based on the detection of Plasmodium falciparum histidine-rich protein (PfHRP) 2, but reports from field tests have questioned their sensitivity and reliability. We hypothesize that the variability in the results of PfHRP2-based RDTs is related to the variability in the target antigen. We tested this hypothesis by examining the genetic diversity of PfHRP2, which includes numerous amino acid repeats, in 75 P. falciparum lines and isolates originating from 19 countries and testing a subset of parasites by use of 2 PfHRP2-based RDTs. We observed extensive diversity in PfHRP2 sequences, both within and between countries. Logistic regression analysis indicated that 2 types of repeats were predictive of RDT detection sensitivity (87.5% accuracy), with predictions suggesting that only 84% of P. falciparum parasites in the Asia-Pacific region are likely to be detected at densities < or = 250 parasites/microL. Our data also indicated that PfHRP3 may play a role in the performance of PfHRP2-based RDTs. These findings provide an alternative explanation for the variable sensitivity in field tests of malaria RDTs that is not due to the quality of the RDTs.

  19. Communication strategies for enhancing understanding of the behavioral implications of genetic and biomarker tests for disease risk: the role of coherence.

    PubMed

    Cameron, Linda D; Marteau, Theresa M; Brown, Paul M; Klein, William M P; Sherman, Kerry A

    2012-06-01

    Individuals frequently have difficulty understanding how behavior can reduce genetically-conferred risk for diseases such as colon cancer. With increasing opportunities to purchase genetic tests, communication strategies are needed for presenting information in ways that optimize comprehension and adaptive behavior. Using the Common-Sense Model, we tested the efficacy of a strategy for providing information about the relationships (links) among the physiological processes underlying disease risk and protective action on understanding, protective action motivations, and willingness to purchase tests. We tested the generalizability of the strategy's effects across varying risk levels, for genetic tests versus tests of a non-genetic biomarker, and when using graphic and numeric risk formats. In an internet-based experiment, 749 adults from four countries responded to messages about a hypothetical test for colon cancer risk. Messages varied by Risk-Action Link Information (provision or no provision of information describing how a low-fat diet reduces risk given positive results, indicating presence of a gene fault), Risk Increment (20%, 50%, or 80% risk given positive results), Risk Format (numeric or graphic presentation of risk increments), and Test Type (genetic or enzyme). Providing risk-action link information enhanced beliefs of coherence (understanding how a low-fat diet reduces risk) and response efficacy (low-fat diets effectively reduce risk) and lowered appraisals of anticipated risk of colon cancer given positive results. These effects held across risk increments, risk formats, and test types. For genetic tests, provision of risk-action link information reduced the amount individuals were willing to pay for testing. Brief messages explaining how action can reduce genetic and biomarker-detected risks can promote beliefs motivating protective action. By enhancing understanding of behavioral control, they may reduce the perceived value of genetic risk information.

  20. A Step-by-Step Guide to Publishing Journal Articles and Strategies for Securing Impactful Publications

    ERIC Educational Resources Information Center

    Onwuegbuzie, Anthony J.

    2016-01-01

    In the last few years, I have been presenting workshops on publishing (among other topics) in many countries across 6 continents. And presenting these workshops in various countries has allowed me to learn the policies and practices of editors of journals representing numerous countries, thereby helping me to broaden the framework for writing…

  1. Comparison of Fecal Collection Methods for Microbiota Studies in Bangladesh

    PubMed Central

    Chen, Jun; Kibriya, Muhammad G.; Chen, Yu; Islam, Tariqul; Eunes, Mahbubul; Ahmed, Alauddin; Naher, Jabun; Rahman, Anisur; Amir, Amnon; Shi, Jianxin; Abnet, Christian C.; Nelson, Heidi; Knight, Rob; Chia, Nicholas; Ahsan, Habibul; Sinha, Rashmi

    2017-01-01

    ABSTRACT To our knowledge, fecal microbiota collection methods have not been evaluated in low- and middle-income countries. Therefore, we evaluated five different fecal sample collection methods for technical reproducibility, stability, and accuracy within the Health Effects of Arsenic Longitudinal Study (HEALS) in Bangladesh. Fifty participants from the HEALS provided fecal samples in the clinic which were aliquoted into no solution, 95% ethanol, RNAlater, postdevelopment fecal occult blood test (FOBT) cards, and fecal immunochemical test (FIT) tubes. Half of the aliquots were frozen immediately at −80°C (day 0) and the remaining samples were left at ambient temperature for 96 h and then frozen (day 4). Intraclass correlation coefficients (ICC) were calculated for the relative abundances of the top three phyla, for two alpha diversity measures, and for four beta diversity measures. The duplicate samples had relatively high ICCs for technical reproducibility at day 0 and day 4 (range, 0.79 to 0.99). The FOBT card and samples preserved in RNAlater and 95% ethanol had the highest ICCs for stability over 4 days. The FIT tube had lower stability measures overall. In comparison to the “gold standard” method using immediately frozen fecal samples with no solution, the ICCs for many of the microbial metrics were low, but the rank order appeared to be preserved as seen by the Spearman correlation. The FOBT cards, 95% ethanol, and RNAlater were effective fecal preservatives. These fecal collection methods are optimal for future cohort studies, particularly in low- and middle-income countries. IMPORTANCE The collection of fecal samples in prospective cohort studies is essential to provide the opportunity to study the effect of the human microbiota on numerous health conditions. However, these collection methods have not been adequately tested in low- and middle-income countries. We present estimates of technical reproducibility, stability at ambient temperature for 4 days, and accuracy comparing a “gold standard” for fecal samples in no solution, 95% ethanol, RNAlater, postdevelopment fecal occult blood test cards, and fecal immunochemical test tubes in a study conducted in Bangladesh. Fecal occult blood test cards and fecal samples stored in 95% ethanol or RNAlater adequately preserve fecal samples in this setting. Therefore, new studies in low- and middle-income countries should include collection of fecal samples using fecal occult blood test cards, 95% ethanol, or RNAlater for prospective cohort studies. PMID:28258145

  2. Continuous-flow solar UVB disinfection reactor for drinking water.

    PubMed

    Mbonimpa, Eric Gentil; Vadheim, Bryan; Blatchley, Ernest R

    2012-05-01

    Access to safe, reliable sources of drinking water is a long-standing problem among people in developing countries. Sustainable solutions to these problems often involve point-of-use or community-scale water treatment systems that rely on locally-available resources and expertise. This philosophy was used in the development of a continuous-flow, solar UVB disinfection system. Numerical modeling of solar UVB spectral irradiance was used to define temporal variations in spectral irradiance at several geographically-distinct locations. The results of these simulations indicated that a solar UVB system would benefit from incorporation of a device to amplify ambient UVB fluence rate. A compound parabolic collector (CPC) was selected for this purpose. Design of the CPC was based on numerical simulations that accounted for the shape of the collector and reflectance. Based on these simulations, a prototype CPC was constructed using materials that would be available and inexpensive in many developing countries. A UVB-transparent pipe was positioned in the focal area of the CPC; water was pumped through the pipe to allow exposure of waterborne microbes to germicidal solar UVB radiation. The system was demonstrated to be effective for inactivation of Escherichia coli, and DNA-weighted UV dose was shown to govern reactor performance. The design of the reactor is expected to scale linearly, and improvements in process performance (relative to results from the prototype) can be expected by use of larger CPC geometry, inclusion of better reflective materials, and application in areas with greater ambient solar UV spectral irradiance than the location of the prototype tests. The system is expected to have application for water treatment among communities in (developing) countries in near-equatorial and tropical locations. It may also have application for disaster relief or military field operations, as well as in water treatment in areas of developed countries that receive relatively intense solar UVB radiation. Copyright © 2012 Elsevier Ltd. All rights reserved.

  3. Use of the Moodle Platform to Promote an Ongoing Learning When Lecturing General Physics in the Physics, Mathematics and Electronic Engineering Programmes at the University of the Basque Country UPV/EHU

    NASA Astrophysics Data System (ADS)

    López, Gabriel A.; Sáenz, Jon; Leonardo, Aritz; Gurtubay, Idoia G.

    2016-08-01

    The Moodle platform has been used to put into practice an ongoing evaluation of the students' Physics learning process. The evaluation has been done on the frame of the course General Physics, which is lectured during the first year of the Physics, Mathematics and Electronic Engineering Programmes at the Faculty of Science and Technology of the University of the Basque Country (UPV/EHU). A test bank with more than 1000 multiple-choice questions, including conceptual and numerical problems, has been prepared. Throughout the course, the students have to answer a 10-question multiple-choice test for every one of the blocks the course is divided in and which were previously treated and worked in the theoretical lectures and problem-solving sessions. The tests are automatically corrected by Moodle, and under certain criteria, the corresponding mark is taken into account for the final mark of the course. According to the results obtained from a statistical study of the data on the student performances during the last four academic years, it has been observed that there exists an actual correlation between the marks obtained in the Moodle tests and the final mark of the course. In addition, it could be deduced that students who have passed the Moodle tests increase their possibilities of passing the course by an odds ratio close to 3.

  4. Observations and Modeling of Environmental and Human Damages by the 2004 Indian Ocean tsunami

    NASA Astrophysics Data System (ADS)

    Goto, K.; Imamura, F.; Koshimura, S.; Yanagisawa, H.

    2008-05-01

    On 26 December 2004, one of the largest tsunamis in human history (the 2004 Indian Ocean tsunami) struck coastal areas of countries surrounding the Indian Ocean, causing severe property damage and loss of life and causing us to think anew about the fearful consequences of a tsunami disaster. The tsunami devastated more than 10 countries around the ocean including Indonesia, Sri Lanka, India, and Thailand. Since its energy remains almost constant, the tsunami wave height grows tremendously in shallow water. It ranged in runups of ~48m on the western shore of Sumatra, ~18m in Thailand, and ~15m in Sri Lanka. The tsunami killed nearly 230,000 people, including visitors from foreign countries, resulting in great economic losses. The tsunami was also affected coastal environment at these countries and induced severe topographic change, and damages to the marine ecosystems as well as vegetations on land. Immediately following the tsunami, number of research teams has investigated damages of environment and human communities by tsunamis. Numerical analyses of tsunami propagation have also been carried out to understand the behavior and wave properties of tsunamis. However, there are few studies that focused on the integration of the field observations and numerical results, nevertheless that such analysis is critically important to evaluate the environmental and human damages by the tsunami. In this contribution, we first review damages to the environment and humans due to the 2004 Indian Ocean tsunami at Thailand, Indonesia, and Sri Lanka based on our field observations, and then we evaluate these damages based on high resolution numerical results. For example, we conducted field observation as well as high-resolution (17 m grid cells) numerical calculation for damages of corals (reef rocks) and mangroves at Pakarang Cape, Thailand. We found that hundreds of reef rocks were emplaced on the tidal bench, and 70 % of mangroves were destroyed at the cape. Our numerical results further clarified that these damages are well explained by the calculated hydraulic force of tsunamis. This kind of analysis that integrated the observation and numerical results is important to evaluate environmental and human damages quantitatively, and to make a future disaster prevention plan.

  5. Testing of a Transport Cask for Research Reactor Spent Fuel - 13003

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mourao, Rogerio P.; Leite da Silva, Luiz; Miranda, Carlos A.

    2013-07-01

    Since the beginning of the last decade three Latin American countries that operate research reactors - Argentina, Brazil and Chile - have been joining efforts to improve the regional capability in the management of spent fuel elements from the TRIGA and MTR reactors operated in the region. A main drive in this initiative, sponsored by the International Atomic Energy Agency, is the fact that no definite solution regarding the back end of the research reactor fuel cycle has been taken by any of the participating country. However, any long-term solution - either disposition in a repository or storage away frommore » reactor - will involve at some stage the transportation of the spent fuel through public roads. Therefore, a licensed cask that provides adequate shielding, assurance of subcriticality, and conformance to internationally accepted safety, security and safeguards regimes is considered a strategic part of any future solution to be adopted at a regional level. As a step in this direction, a packaging for the transport of irradiated fuel for MTR and TRIGA research reactors was designed by the tri-national team and a half-scale model equipped with the MTR version of the internal basket was constructed in Argentina and Brazil and tested in Brazil. Three test campaigns have been carried out so far, covering both normal conditions of transportation and hypothetical accident conditions. After failing the tests in the first two test series, the specimen successfully underwent the last test sequence. A second specimen, incorporating the structural improvements in view of the previous tests results, will be tested in the near future. Numerical simulations of the free drop and thermal tests are being carried out in parallel, in order to validate the computational modeling that is going to be used as a support for the package certification. (authors)« less

  6. Results from early programmatic implementation of Xpert MTB/RIF testing in nine countries

    PubMed Central

    2014-01-01

    Background The Xpert MTB/RIF assay has garnered significant interest as a sensitive and rapid diagnostic tool to improve detection of sensitive and drug resistant tuberculosis. However, most existing literature has described the performance of MTB/RIF testing only in study conditions; little information is available on its use in routine case finding. TB REACH is a multi-country initiative focusing on innovative ways to improve case notification. Methods We selected a convenience sample of nine TB REACH projects for inclusion to cover a range of implementers, regions and approaches. Standard quarterly reports and machine data from the first 12 months of MTB/RIF implementation in each project were utilized to analyze patient yields, rifampicin resistance, and failed tests. Data was collected from September 2011 to March 2013. A questionnaire was implemented and semi-structured interviews with project staff were conducted to gather information on user experiences and challenges. Results All projects used MTB/RIF testing for people with suspected TB, as opposed to testing for drug resistance among already diagnosed patients. The projects placed 65 machines (196 modules) in a variety of facilities and employed numerous case-finding strategies and testing algorithms. The projects consumed 47,973 MTB/RIF tests. Of valid tests, 7,195 (16.8%) were positive for MTB. A total of 982 rifampicin resistant results were found (13.6% of positive tests). Of all tests conducted, 10.6% failed. The need for continuous power supply was noted by all projects and most used locally procured solutions. There was considerable heterogeneity in how results were reported and recorded, reflecting the lack of standardized guidance in some countries. Conclusions The findings of this study begin to fill the gaps among guidelines, research findings, and real-world implementation of MTB/RIF testing. Testing with Xpert MTB/RIF detected a large number of people with TB that routine services failed to detect. The study demonstrates the versatility and impact of the technology, but also outlines various surmountable barriers to implementation. The study is not representative of all early implementer experiences with MTB/RIF testing but rather provides an overview of the shared issues as well as the many different approaches to programmatic MTB/RIF implementation. PMID:24383553

  7. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Flintoff, F.

    With the advent of industrialisation and urbanisation, developing countries are faced with numerous problems, one of the biggest being the provision of an effective solid wastes system appropriate to their varying climates and economies. The problems facing third world countries are discussed, these include the lack of a network of district depots, inadequate automotive servicing facilities and technical expertise.

  8. Orion Crew Module Aerodynamic Testing

    NASA Technical Reports Server (NTRS)

    Murphy, Kelly J.; Bibb, Karen L.; Brauckmann, Gregory J.; Rhode, Matthew N.; Owens, Bruce; Chan, David T.; Walker, Eric L.; Bell, James H.; Wilson, Thomas M.

    2011-01-01

    The Apollo-derived Orion Crew Exploration Vehicle (CEV), part of NASA s now-cancelled Constellation Program, has become the reference design for the new Multi-Purpose Crew Vehicle (MPCV). The MPCV will serve as the exploration vehicle for all near-term human space missions. A strategic wind-tunnel test program has been executed at numerous facilities throughout the country to support several phases of aerodynamic database development for the Orion spacecraft. This paper presents a summary of the experimental static aerodynamic data collected to-date for the Orion Crew Module (CM) capsule. The test program described herein involved personnel and resources from NASA Langley Research Center, NASA Ames Research Center, NASA Johnson Space Flight Center, Arnold Engineering and Development Center, Lockheed Martin Space Sciences, and Orbital Sciences. Data has been compiled from eight different wind tunnel tests in the CEV Aerosciences Program. Comparisons are made as appropriate to highlight effects of angle of attack, Mach number, Reynolds number, and model support system effects.

  9. Chronic kidney disease in low- and middle-income countries

    PubMed Central

    Stanifer, John W.; Muiru, Anthony; Jafar, Tazeen H.; Patel, Uptal D.

    2016-01-01

    Most of the global burden of chronic kidney disease (CKD) is occurring in low- and middle-income countries (LMICs). As a result of rapid urbanization in LMICs, a growing number of populations are exposed to numerous environmental toxins, high infectious disease burdens and increasing rates of noncommunicable diseases. For CKD, this portends a high prevalence related to numerous etiologies, and it presents unique challenges. A better understanding of the epidemiology of CKD in LMICs is urgently needed, but this must be coupled with strong public advocacy and broad, collaborative public health efforts that address environmental, communicable, and non-communicable risk factors. PMID:27217391

  10. The role of dispositional traits in accounting for country and ethnic group differences on adjustment.

    PubMed

    Matsumoto, David; Nakagawa, Sanae; Estrada, Aaron

    2009-02-01

    Country and ethnic group differences on adjustment have been demonstrated numerous times, and the source of these differences has been typically interpreted as cultural. We report two studies in which country (Study 1) and ethnic group (Study 2) differences on depression, anxiety, optimism versus pessimism, well-being, and self-esteem are mediated by dispositional traits. These findings provide an alternative explanation for previously reported country and ethnic group differences on these variables and encourage researchers to consider multiple sources, including traits, in their models and studies.

  11. Cooperative Monitoring Center Occasional Paper/4: Missile Control in South Asia and the Role of Cooperative Monitoring Technology

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kamal, N.; Sawhney, P.

    1998-10-01

    The succession of nuclear tests by India and Pakistan in May 1998 has changed the nature of their missile rivalry, which is only one of numerous manifestations of their relationship as hardened adversaries, deeply sensitive to each other's existing and evolving defense capabilities. The political context surrounding this costly rivalry remains unmediated by arms control measures or by any nascent prospect of detente. As a parallel development, sensible voices in both countries will continue to talk of building mutual confidence through openness to avert accidents, misjudgments, and misinterpretations. To facilitate a future peace process, this paper offers possible suggestions formore » stabilization that could be applied to India's and Pakistan's missile situation. Appendices include descriptions of existing missile agreements that have contributed to better relations for other countries as well as a list of the cooperative monitoring technologies available to provide information useful in implementing subcontinent missile regimes.« less

  12. Numeracy Skills and the Numerate Environment: Affordances and Demands

    ERIC Educational Resources Information Center

    Evans, Jeff; Yasukawa, Keiko; Mallows, David; Creese, Brian

    2017-01-01

    In the 2012 PIAAC Survey of Adult Skills of 23 industrialised countries, the UK (England & NI) scored below average on adult numeracy. Several recommendations focus on the need for (some) individuals in the population to undergo training. Yet, even in "high-performing countries" like the Netherlands, many adults (1.5M) score at or…

  13. Algeria: Revolution, Army and Political Power

    ERIC Educational Resources Information Center

    Zeraoui, Zidane

    2012-01-01

    Despite the numerous similarities among the Arab countries that explain the rapid popular movements since the end of 2010, the case of Algeria presents particular features. It shares the same inequalities and social challenges as the rest of the countries in the region. However, the revolutionary process in Algeria between 1954 and 1962 and the…

  14. School Choice and Academic Performance: Some Evidence from Developing Countries

    ERIC Educational Resources Information Center

    Tooley, James; Bao, Yong; Dixon, Pauline; Merrifield, John

    2011-01-01

    There is widespread concern about differences in the quality of state-run and private schooling. The concerns are especially severe in the numerous developing countries where much of the population has left state-provided schooling for private schooling, including many private schools not recognized by the government. The fees charged by the…

  15. Occupational health standards. An international comparison.

    PubMed

    Holmberg, B; Winell, M

    1977-03-01

    The background for establishing standards for toxic agents is reviewed, and the standards of 14 different countries, including Sweden, are compared with special reference to criteria and organizational aspects. The differences among countries in the numerical limit values for toxic substances are largely due to differences in definitions, biomedical criteria, technical feasibility and sociopolitical judgements.

  16. Meritocracy, Tracking, and Elitism: Differentiated Citizenship Education in the United States and Singapore

    ERIC Educational Resources Information Center

    Ho, Li-Ching

    2014-01-01

    Numerous studies have highlighted a clear civic achievement gap between students from different ethnic and economic backgrounds in countries such as Singapore and the United States. Concurrently, researchers from both countries have noted that access to government and civics classes and curricula differs considerably across and within schools and…

  17. Global survey of hospital pharmacy practice.

    PubMed

    Doloresco, Fred; Vermeulen, Lee C

    2009-03-01

    The current state of hospital pharmacy practice around the globe and key issues facing international hospital pharmacy practice were studied. This survey assessed multiple aspects of hospital pharmacy practice within each of the Member States recognized by the United Nations. An official respondent from each nation was identified by a structured nomination process. The survey instrument was developed; pilot tested; translated into English, French, and Spanish; and distributed in July 2007. The nature, scope, and breadth of hospital pharmacy practices in medication procurement, prescribing, preparation and distribution, administration, outcomes monitoring, and human resources and training were evaluated. Descriptive statistics were used to characterize the responses. Eighty-five countries (44% of the 192 Member States) responded to the survey. The respondent sample of countries was representative of all nations in terms of population, geographic region, World Health Organization region, and level of economic development. In addition to qualifying the nature of hospital pharmacy practice, the survey highlighted numerous challenges facing the profession of pharmacy in the hospital setting around the globe, including access to medicines and adequately trained pharmacists. While the practice of hospital pharmacy differs from country to country, many nations face similar challenges, regardless of their population, location, or wealth. These survey results provide a basis for identifying opportunities for growth and development, as well as for international collaboration, to advance the profession of pharmacy and ensure that patients worldwide receive the care that they deserve.

  18. Review of national research ethics regulations and guidelines in Middle Eastern Arab countries

    PubMed Central

    2012-01-01

    Background Research ethics guidelines are essential for conducting medical research. Recently, numerous attempts have been made to establish national clinical research documents in the countries of the Middle East. This article analyzes these documents. Methods Thirteen Arab countries in the Middle East were explored for available national codes, regulations, and guidelines concerning research ethics, and 10 documents from eight countries were found. We studied these documents, considering the ethical principles stated in the Declaration of Helsinki, the Council for International Organizations of Medical Sciences (CIOMS) guidelines, and the International Conference of Harmonization - Guidelines for Good Clinical Practice (ICH-GCP). Our paper comprises a complete list of protections, such as confidentiality, informed consent, ethics committees, and others. Results This study found different levels and kinds of research ethics regulations and guidelines in the countries examined. Two groups can be distinguished: the countries in the first group have one or more research ethics regulations or guidelines, while the countries in the second group have not yet established any. Most of the documents showed various degrees of deficiencies in regard to ethical protection. The majority of the documents that were examined refer to one or more international documents on biomedical research ethics. Conclusions Recently, a lot of efforts have been made in many countries in the Middle East. However, compared with international documents, most of the research ethics documents in use in this region demonstrate numerous deficiencies. As it relates to these documents, extensive differences could be observed in regard to development, structure, content, and reference to international guidelines. PMID:23234422

  19. The role of private health providers in HIV testing: analysis of data from 18 countries

    PubMed Central

    2014-01-01

    Introduction HIV testing and counseling is a critical component of the overall response to the HIV epidemic in low and middle income countries. To date, little attention has been paid to the role of private for-profit providers in HIV testing. Methods We use data from Demographic and Health Surveys and AIDS Indicators Surveys to explore the extent to which this sector provides HIV testing in 18 developing countries. Results We find that use of the private sector for HIV testing varies significantly by country, with private for-profit providers playing a significant role in some countries and a relatively minor one in others. At the country level, use of private providers for HIV testing is correlated with use of private providers for other health services yet, in many countries, significant differences between use of the private sector for HIV testing and other services exist. Within countries, we find that wealth is strongly associated with use of the private sector for HIV testing in most countries, but the relative socio-economic profile of clients who receive an HIV test from a private provider varies considerably across countries. On the one measure of quality to which we have access, reported adherence to antenatal care testing guidelines, there are no statistically significant differences in performance between public and private for-profit providers in most countries after controlling for wealth. Conclusions These results suggest that strategies for supervising and engaging private health providers with regard to HIV testing should be country specific and take into account local context. PMID:24884851

  20. The role of private health providers in HIV testing: analysis of data from 18 countries.

    PubMed

    Johnson, Doug; Cheng, Xi

    2014-05-12

    HIV testing and counseling is a critical component of the overall response to the HIV epidemic in low and middle income countries. To date, little attention has been paid to the role of private for-profit providers in HIV testing. We use data from Demographic and Health Surveys and AIDS Indicators Surveys to explore the extent to which this sector provides HIV testing in 18 developing countries. We find that use of the private sector for HIV testing varies significantly by country, with private for-profit providers playing a significant role in some countries and a relatively minor one in others. At the country level, use of private providers for HIV testing is correlated with use of private providers for other health services yet, in many countries, significant differences between use of the private sector for HIV testing and other services exist. Within countries, we find that wealth is strongly associated with use of the private sector for HIV testing in most countries, but the relative socio-economic profile of clients who receive an HIV test from a private provider varies considerably across countries. On the one measure of quality to which we have access, reported adherence to antenatal care testing guidelines, there are no statistically significant differences in performance between public and private for-profit providers in most countries after controlling for wealth. These results suggest that strategies for supervising and engaging private health providers with regard to HIV testing should be country specific and take into account local context.

  1. Asbestos in Asia.

    PubMed

    Leong, Su Lyn; Zainudin, Rizka; Kazan-Allen, Laurie; Robinson, Bruce W

    2015-05-01

    Asbestos is a global killer. Despite lessons learned in the developed world on the use of asbestos and its hazardous pulmonary consequences, its use continues to increase in Asia. Although some countries such as Japan, Korea and Singapore have curtailed the use of this mineral, there are numerous countries in Asia that continue to mine, import and use this fibre, particularly China, which is one of the largest consumers in the world. Numerous factors ranging from political and economic to the lack of understanding of asbestos and the management of asbestos-related lung disease are keys to this observed trend. Awareness of these factors combined with early intervention may prevent the predicted Asian 'tsunami' of asbestos diseases. © 2015 Asian Pacific Society of Respirology.

  2. Perception of Mobbing by Teachers and Organizational Depression: A Correlational Model Study

    ERIC Educational Resources Information Center

    Toytok, Esef Hakan

    2017-01-01

    As is known, mobbing (intimidation) is an important concept being subject to many researches in numerous fields and many researchers suggest that this concept has the power to directly affect organizational structures. Even though the concept of mobbing changes from country to country, culture to culture and organization to organization, it is…

  3. Using mass spectrometry to determine the relative susceptibility of PrP polymorphisms to atypical scrapie

    USDA-ARS?s Scientific Manuscript database

    A novel form of scrapie was described in 1998 and referred to as Nor98 for the country of origin and date of its discovery. Since then it has been found in numerous countries, including New Zealand and Australia, and has been renamed atypical scrapie. Unlike classical scrapie, the epidemiology of th...

  4. Urban forest sustainability in the United States

    Treesearch

    David J. Nowak

    2017-01-01

    Urban forests in the United States provide numerous ecosystem services that vary in magnitude across the country and are valued in the billions of dollars per year. Urban tree cover has been on the decline in recent years. Numerous forces for change will continue to alter urban forests in the coming years (i.e., development, climate change, insects and diseases,...

  5. Neuropsychology in South Africa: confronting the challenges of specialist practice in a culturally diverse developing country.

    PubMed

    Watts, Ann D; Shuttleworth-Edwards, Ann B

    2016-11-01

    This was an invited paper on the history and current status of neuropsychology in South Africa. Information was gathered from literature searches, personal communication, and the authors' experiences while occupying relevant professional and academic positions for over 30 years. Since its origins in the 1950s, the development of neuropsychology in South Africa has faced numerous challenges, against a background of extreme sociocultural and socioeconomic disparity in the country that is on-going. The creation of the South African Clinical Neuropsychological Society in the 1980s, a credentialing and training body, gave impetus to the discipline. In the absence of a neuropsychology category within the South African professional framework, university instruction has been ad hoc with vastly different levels of competency depending on the institution involved. The small number of practitioners and/or academics involved in neuropsychology includes mainly masters, and some doctoral level psychologists registered in clinical, counseling or educational categories. A prime emphasis of neuropsychological research has been local norming of psychometric tests to facilitate valid assessment practices in the country. South Africa is on the cusp of achieving a hard-won neuropsychology professional register. It is anticipated that this development will provide impetus to the discipline by promoting training programs, the creation of neuropsychology posts, wider service delivery, and increased research funding. Despite significant challenges in a culturally diverse, developing country, neuropsychology has evolved sufficiently to warrant the creation of a separate category in the professional framework. This development will facilitate training, research, and services in the country.

  6. Test development and use in five Iberian Latin American countries.

    PubMed

    Wechsler, Solange M; Oakland, Thomas; León, Carmem; Vivas, Eleonora; de Almeida, Leandro; Franco, Amanda; Pérez-Solís, María; Contini, Norma

    2014-08-01

    The abundance of scholarship on test development and use generally is higher in English-speaking than in Iberian Latin American countries. The purpose of this article is to help overcome this imbalance by describing and identifying similarities and differences in test development and use in two Iberian (Portugal and Spain) and three of the largest Latin American (Argentina, Brazil, and Venezuela) countries. The stages of test development in each country, roles of professional associations, presence of standards for test use, professionals' educational training, commonly used tests, together with prominent challenges to continued progress are discussed. Test development and use in these five countries are transitioning from a dependence on the use of translated tests to greater reliance on adapted and finally nationally constructed tests. Continued growth requires adherence to international standards guiding test development and use. Stronger alliance among professional associations in the Iberian Latin American countries could serve as a catalyst to promote test development in these regions. © 2014 International Union of Psychological Science.

  7. A New Knowledge Society Index: Global Tendencies and an Analysis of Turkey

    ERIC Educational Resources Information Center

    Demir, Oguz; Genc, Elif Guneren; Alp, Elcin Aykac; Yildirim, Figen

    2015-01-01

    Numerous studies have examined the growth rate and the level of development of countries. According to economy, sociology, and even history, it can be easily observed that knowledge is one of the most important indicators for countries to achieve sustainable growth and development. Education is seen as the main input for a society to be considered…

  8. Mental Health Professionals Unite to Support Japanese and Japanese Americans

    ERIC Educational Resources Information Center

    Ikeda, Maiko; Inaba, Jennifer Saeko; Ikeda, Ayako Christina; Kihara, Miki

    2011-01-01

    On Friday, March 11, 2011, one of the worst disasters in the world hit the country of Japan. A magnitude 9.0 earthquake struck off the coast of Japan, forever changing the lives of the people and the state of the country. Not only were lives lost and homes destroyed, the tsunami that followed caused numerous nuclear accidents around the Fukushima…

  9. Smokers' Perceptions of Sources of Advice about Quitting: Findings from the Australian Arm of the ITC 4-Country Survey

    ERIC Educational Resources Information Center

    Balmford, James; Borland, Ron

    2017-01-01

    Smokers are exposed to advice about quitting from numerous sources. Within the 2013 ITC 4-Country Survey, 1211 Australian smokers or recent ex-smokers rated the perceived importance of eight sources of advice, categorized into evidence-based, non evidence-based, personal experience and vicarious experience (two items each), and also rated their…

  10. Mycobacterium tuberculosis drug-resistance testing: challenges, recent developments and perspectives.

    PubMed

    Schön, T; Miotto, P; Köser, C U; Viveiros, M; Böttger, E; Cambau, E

    2017-03-01

    Drug-resistance testing, or antimicrobial susceptibility testing (AST), is mandatory for Mycobacterium tuberculosis in cases of failure on standard therapy. We reviewed the different methods and techniques of phenotypic and genotypic approaches. Although multiresistant and extensively drug-resistant (MDR/XDR) tuberculosis is present worldwide, AST for M. tuberculosis (AST-MTB) is still mainly performed according to the resources available rather than the drug-resistance rates. Phenotypic methods, i.e. culture-based AST, are commonly used in high-income countries to confirm susceptibility of new cases of tuberculosis. They are also used to detect resistance in tuberculosis cases with risk factors, in combination with genotypic tests. In low-income countries, genotypic methods screening hot-spot mutations known to confer resistance were found to be easier to perform because they avoid the culture and biosafety constraint. Given that genotypic tests can rapidly detect the prominent mechanisms of resistance, such as the rpoB mutation for rifampicin resistance, we are facing new challenges with the observation of false-resistance (mutations not conferring resistance) and false-susceptibility (mutations different from the common mechanism) results. Phenotypic and genotypic approaches are therefore complementary for obtaining a high sensitivity and specificity for detecting drug resistances and susceptibilities to accurately predict MDR/XDR cure and to gather relevant data for resistance surveillance. Although AST-MTB was established in the 1960s, there is no consensus reference method for MIC determination against which the numerous AST-MTB techniques can be compared. This information is necessary for assessing in vitro activity and setting breakpoints for future anti-tuberculosis agents. Copyright © 2016 European Society of Clinical Microbiology and Infectious Diseases. Published by Elsevier Ltd. All rights reserved.

  11. Numerical modeling of mosquito population dynamics of Aedes aegypti.

    PubMed

    Yamashita, William M S; Das, Shyam S; Chapiro, Grigori

    2018-04-16

    The global incidences of dengue virus have increased the interest in studying and understanding the mosquito population dynamics. It is predominantly spread by Aedes aegypti in the tropical and sub-tropical countries in the world. Understanding these dynamics is important for public health in countries where climatic and environmental conditions are favorable for the propagation of these diseases. For this reason, a new model has been proposed to investigate the population dynamics of mosquitoes in a city. The present paper discusses the numerical modeling of population dynamics of Ae. aegypti mosquitoes in an urban neighborhood of a city using the finite volume method. The model describes how populations spread through the city assisted by the wind. This model allows incorporating external factors (wind and chemical insecticides) and topography data (streets, building blocks, parks, forests and beach). The proposed model has been successfully tested in examples involving two Brazilian cities (City center, Juiz de Fora and Copacabana Beach, Rio de Janeiro). Invasion phenomena of Ae. aegypti mosquitoes have been observed in each of the simulations. It was observed that, inside the blocks, the growth of the population for both winged and aquatic phase causes an infestation of Ae. aegypti in a short time. Within the blocks the mosquito population was concentrated and diffused slowly. In the streets, there was a long-distance spread, which was influenced by wind and diffusion with a low concentration of mosquito population. The model was also tested taking into account chemical insecticides spread in two different configurations. It has been observed that the insecticides have a significant effect on the mosquito population for both winged and aquatic phases when the chemical insecticides spread more uniformly along all the streets in a neighborhood of a city. The presented methodology can be employed to evaluate and to understand the epidemic risks in a specific region of the city. Moreover the model allows an increase in efficiency of the existing mosquito population control techniques and to theoretically test new methods before involving the human population.

  12. GMOtrack: generator of cost-effective GMO testing strategies.

    PubMed

    Novak, Petra Krau; Gruden, Kristina; Morisset, Dany; Lavrac, Nada; Stebih, Dejan; Rotter, Ana; Zel, Jana

    2009-01-01

    Commercialization of numerous genetically modified organisms (GMOs) has already been approved worldwide, and several additional GMOs are in the approval process. Many countries have adopted legislation to deal with GMO-related issues such as food safety, environmental concerns, and consumers' right of choice, making GMO traceability a necessity. The growing extent of GMO testing makes it important to study optimal GMO detection and identification strategies. This paper formally defines the problem of routine laboratory-level GMO tracking as a cost optimization problem, thus proposing a shift from "the same strategy for all samples" to "sample-centered GMO testing strategies." An algorithm (GMOtrack) for finding optimal two-phase (screening-identification) testing strategies is proposed. The advantages of cost optimization with increasing GMO presence on the market are demonstrated, showing that optimization approaches to analytic GMO traceability can result in major cost reductions. The optimal testing strategies are laboratory-dependent, as the costs depend on prior probabilities of local GMO presence, which are exemplified on food and feed samples. The proposed GMOtrack approach, publicly available under the terms of the General Public License, can be extended to other domains where complex testing is involved, such as safety and quality assurance in the food supply chain.

  13. Variation in Educational Outcomes and Policies across Countries and of Schools within Countries. NBER Working Paper No. 16293

    ERIC Educational Resources Information Center

    Freeman, Richard B.; Machin, Stephen; Viarengo, Martina

    2010-01-01

    This study examines the variation in educational outcomes across and within countries using the TIMSS mathematics tests. It documents the wide cross-country variation in the level and dispersion of test scores. Countries with the highest test scores are those with the least inequality in scores, which suggests a "virtuous" equity-efficiency…

  14. A health priority for developing countries: the prevention of chronic fetal malnutrition.

    PubMed

    Villar, J; Altobelli, L; Kestler, E; Beliźan, J

    1986-01-01

    A prospective study of 3557 consecutively born neonates from a lower middle class district in Guatemala City documented a 23.8% incidence of intrauterine growth retardation due to fetal malnutrition. Those infants whose weights are below the 10th percentile of a sex- and race-specific birthweight and gestational age distribution, based on a developed country population, were considered to manifest intrauterine growth retardation. Ponderal index values were then used to further classify this population as having chronic fetal malnutrition (above the 10th percentile of the standard distribution) or subacute fetal malnutrition (below the 10th percentile); the incidences of these conditions were 79.1% and 20.8%, respectively. The results of numerous studies carried out in various populations suggest that developing countries have a higher incidence of chronically malnourished infants within the intrauterine growth retardation population, while subacute fetal malnutrition is more prevalent in developed countries. Moreover, it has been shown that chronically malnourished infants do not recover from their intrauterine damage and score the lowest in mental development tests even up to school age. They remain lighter, shorter, and with a smaller head circumference until at least 3 years of age. Based on the incidence rates ascertained in this study, it can be estimated that at least 2 million infants born each year in Latin America are at risk of chronic intrauterine growth retardation. Screening programs are needed to identify at-risk mothers early in pregnancy so that medical and nutritional interventions can be implemented.

  15. Review of numerical methods for simulation of the aortic root: Present and future directions

    NASA Astrophysics Data System (ADS)

    Mohammadi, Hossein; Cartier, Raymond; Mongrain, Rosaire

    2016-05-01

    Heart valvular disease is still one of the main causes of mortality and morbidity in develop countries. Numerical modeling has gained considerable attention in studying hemodynamic conditions associated with valve abnormalities. Simulating the large displacement of the valve in the course of the cardiac cycle needs a well-suited numerical method to capture the natural biomechanical phenomena which happens in the valve. The paper aims to review the principal progress of the numerical approaches for studying the hemodynamic of the aortic valve. In addition, the future directions of the current approaches as well as their potential clinical applications are discussed.

  16. Assessing dementia in resource-poor regions.

    PubMed

    Maestre, Gladys E

    2012-10-01

    The numbers and proportions of elderly are increasing rapidly in developing countries, where prevalence of dementia is often high. Providing cost-effective services for dementia sufferers and their caregivers in these resource-poor regions poses numerous challenges; developing resources for diagnosis must be the first step. Capacity building for diagnosis involves training and education of healthcare providers, as well as the general public, development of infrastructure, and resolution of economic and ethical issues. Recent progress in some low-to-middle-income countries (LMICs) provides evidence that partnerships between wealthy and resource-poor countries, and between developing countries, can improve diagnostic capabilities. Without the involvement of the mental health community of developed countries in such capacity-building programs, dementia in the developing world is a disaster waiting to happen.

  17. International migration and the propagation of HIV in sub-Saharan Africa.

    PubMed

    Docquier, F; Vasilakis, Ch; Tamfutu Munsi, D

    2014-05-01

    In this paper, we identify and quantify the role of international migration in the propagation of HIV across sub-Saharan African countries. We use panel data on bilateral migration flows and HIV prevalence rates covering 44 countries after 1990. Controlling for unobserved heterogeneity, reverse causality, reflection issues, incorrect treatment of country fixed effects and spatial autocorrelation, we find evidence of a highly robust emigration-induced propagation mechanism. On the contrary, immigration has no significant effect. Numerical experiments reveal that the long-run effect of emigration accounts for more than 4 percent of the number of HIV cases in 15 countries (and more than 20 percent in 6 countries). Copyright © 2014 Elsevier B.V. All rights reserved.

  18. Some Interesting Data About Women Physicists in Cuba (abstract)

    NASA Astrophysics Data System (ADS)

    de Fuentes, Olimpia Arias

    2009-04-01

    Although the number of women physicists in Cuba, as in the entire world, is less than men physicists, their presence in the academic leadership is strong, unlike the limited women's role in many other countries. Some interesting numeral data are presented to demonstrate this affirmation. This fact emphasizes the advantages reached by women and the increasing prestige obtained by women physicists in our country.

  19. Reviewing the Pioneering Roles of Gallaudet University Alumni in Advancing Deaf Education and Services in Developing Countries: Insights and Challenges from Nigeria

    ERIC Educational Resources Information Center

    Eleweke, C. Jonah; Agboola, Isaac O.; Guteng, Simon I.

    2015-01-01

    The advancement of deaf education and services in numerous developing countries can be traced to the pioneering efforts of many Gallaudet University alumni. In Africa, for instance, the work of one such great alumnus, Dr. Andrew Foster, stands out. Foster is credited with efforts that resulted in the establishment of over 30 educational…

  20. Multi-Country Experience in Delivering a Joint Course on Software Engineering--Numerical Results

    ERIC Educational Resources Information Center

    Budimac, Zoran; Putnik, Zoran; Ivanovic, Mirjana; Bothe, Klaus; Zdravkova, Katerina; Jakimovski, Boro

    2014-01-01

    A joint course, created as a result of a project under the auspices of the "Stability Pact of South-Eastern Europe" and DAAD, has been conducted in several Balkan countries: in Novi Sad, Serbia, for the last six years in several different forms, in Skopje, FYR of Macedonia, for two years, for several types of students, and in Tirana,…

  1. Specific physiological and biomechanical performance in elite, sub-elite and in non-elite male team handball players.

    PubMed

    Wagner, Herbert; Fuchs, Philip X; von Duvillard, Serge P

    2018-01-01

    Team handball is a dynamic sport game that is played professionally in numerous countries. However, knowledge about training and competition is based mostly on practical experience due to limited scientific studies. Consequently, the aims of our study were to compare specific physiological and biomechanical performance in elite, sub-elite and in non-elite male team handball players. Thirty-six elite, sub-elite and non-elite male team handball players performed a game based performance test, upper-body and lower-body strength tests, 30-m sprint test, counter movement jump test and an incremental treadmill running test. Significant differences (P<0.05) were found for the peak oxygen uptake, heart rate, offense and defense time, jump height and ball velocity during the jump throw in the game based performance test, maximal oxygen uptake in the incremental treadmill running test as well as in maximal leg strength and leg explosive strength in the isometric strength test. Elite male players have an enhanced specific agility, a better throwing performance, a higher team handball specific oxygen uptake and higher leg strength compared to sub-elite and non-elite players. Based on these results we recommend that training in team handball should focus on game based training methods to improve performance in specific agility, endurance and technique.

  2. Palliative Care Medical Education in European Universities: A Descriptive Study and Numerical Scoring System Proposal for Assessing Educational Development.

    PubMed

    Carrasco, José Miguel; Lynch, Thomas J; Garralda, Eduardo; Woitha, Kathrin; Elsner, Frank; Filbet, Marilène; Ellershaw, John E; Clark, David; Centeno, Carlos

    2015-10-01

    The lack of palliative medicine (PM) education has been identified as a barrier to the development of the discipline. A number of international institutions have called for its implementation within undergraduate medical curricula. The objectives are to describe the situation of undergraduate PM education in Europe and to propose a scoring system to evaluate its status. This descriptive study was conducted with data provided by key experts from countries of the World Health Organization European Region (n = 53). A numerical scoring system was developed through consensus techniques. Forty-three countries (81%) provided the requested information. In 13 countries (30%), a PM course is taught in all medical schools, being compulsory in six of them (14%). In 15 countries (35%), PM is taught in at least one university. In 14 countries (33%), PM is not taught within medical curricula. A full professor of PM was identified in 40% of countries. Three indicators were developed to construct a scale (rank 0-100) of educational development: 1) proportion of medical schools that teach PM (weight = 32%); 2) proportion of medical schools that offer PM as a compulsory subject (weight = 40%); 3) total number of PM professors (weight = 28%). The highest level of PM educational development was found in Israel, Norway, the U.K., Belgium, France, Austria, Germany, and Ireland. PM is taught in a substantial number of undergraduate medical programs at European universities, and a qualified teaching structure is emerging; however, there is a wide variation in the level of PM educational development between individual countries. Copyright © 2015 American Academy of Hospice and Palliative Medicine. Published by Elsevier Inc. All rights reserved.

  3. Population patterns in World’s administrative units

    PubMed Central

    Miramontes, Pedro; Cocho, Germinal

    2017-01-01

    Whereas there has been an extended discussion concerning city population distribution, little has been said about that of administrative divisions. In this work, we investigate the population distribution of second-level administrative units of 150 countries and territories and propose the discrete generalized beta distribution (DGBD) rank-size function to describe the data. After testing the balance between the goodness of fit and number of parameters of this function compared with a power law, which is the most common model for city population, the DGBD is a good statistical model for 96% of our datasets and preferred over a power law in almost every case. Moreover, the DGBD is preferred over a power law for fitting country population data, which can be seen as the zeroth-level administrative unit. We present a computational toy model to simulate the formation of administrative divisions in one dimension and give numerical evidence that the DGBD arises from a particular case of this model. This model, along with the fitting of the DGBD, proves adequate in reproducing and describing local unit evolution and its effect on the population distribution. PMID:28791153

  4. Ebola Surveillance - Guinea, Liberia, and Sierra Leone.

    PubMed

    McNamara, Lucy A; Schafer, Ilana J; Nolen, Leisha D; Gorina, Yelena; Redd, John T; Lo, Terrence; Ervin, Elizabeth; Henao, Olga; Dahl, Benjamin A; Morgan, Oliver; Hersey, Sara; Knust, Barbara

    2016-07-08

    Developing a surveillance system during a public health emergency is always challenging but is especially so in countries with limited public health infrastructure. Surveillance for Ebola virus disease (Ebola) in the West African countries heavily affected by Ebola (Guinea, Liberia, and Sierra Leone) faced numerous impediments, including insufficient numbers of trained staff, community reticence to report cases and contacts, limited information technology resources, limited telephone and Internet service, and overwhelming numbers of infected persons. Through the work of CDC and numerous partners, including the countries' ministries of health, the World Health Organization, and other government and nongovernment organizations, functional Ebola surveillance was established and maintained in these countries. CDC staff were heavily involved in implementing case-based surveillance systems, sustaining case surveillance and contact tracing, and interpreting surveillance data. In addition to helping the ministries of health and other partners understand and manage the epidemic, CDC's activities strengthened epidemiologic and data management capacity to improve routine surveillance in the countries affected, even after the Ebola epidemic ended, and enhanced local capacity to respond quickly to future public health emergencies. However, the many obstacles overcome during development of these Ebola surveillance systems highlight the need to have strong public health, surveillance, and information technology infrastructure in place before a public health emergency occurs. Intense, long-term focus on strengthening public health surveillance systems in developing countries, as described in the Global Health Security Agenda, is needed.The activities summarized in this report would not have been possible without collaboration with many U.S and international partners (http://www.cdc.gov/vhf/ebola/outbreaks/2014-west-africa/partners.html).

  5. Work of the Tamm-Sakharov group on the first hydrogen bomb

    NASA Astrophysics Data System (ADS)

    Ritus, V. I.

    2014-09-01

    This review is an extended version of a report delivered at a session of the Department of Physical Sciences, the Department of Energetics, Mechanical Engineering, Mechanics, and Control Processes, and the Coordination Council on Technical Sciences of the RAS devoted to the 60th anniversary of the first hydrogen bomb test. The significant physical ideas suggested by A D Sakharov and V L Ginzburg underlying our first hydrogen bomb, RDS-6s, and numerous concrete problems and difficulties that had to be solved and overcome in designing thermonuclear weapons are presented. The understanding of the country's leaders and the Atomic Project managers of the exceptional role of fundamental science in the appearance and implementation of our scientists' concrete ideas and suggestions is emphasized.

  6. The trajectories of EAEC countries development: Numerical analysis of competitive strategies in investments

    NASA Astrophysics Data System (ADS)

    Shelomentsev, A. G.; Medvedev, M. A.; Isaichik, K. F.; Dyomina, M. I.; Berg, I. A.; Kit, M.

    2017-12-01

    This paper discusses comparative analysis of trajectories in the development of participating countries of the Eurasian Economic Union (EAEC) in a two-dimensional phase space. The coordinates in the space is represented by the value of a dynamic variable that is a key indicator of the country's development, and the rate of its relative growth. This allows for construction of a ternary classification diagram describing competitive behavior strategies of countries in question. The comparative analysis was run for two primary factors: the size of investment in the main capital and R&D spendings. The authors carried out analysis and identification of competitive strategies for the behavior of the EAEC countries, as well as he proposed conclusions and recommendations on improving the policy of economic development.

  7. [Present state of countermeasure to AIDS in the world today].

    PubMed

    Takakuwa, E

    1997-11-01

    1. Only about 10 years have passed since HIV was discovered but WHO presumes that there will be 30 to 40 million infected cases by the year 2,000. This then possesses the possibility of more frequent contact with such persons and thus means we must look for how to protect ourselves. I would like to discuss the present state of AIDS, particularly in eastern European countries such as Bulgaria, Hungary, Romania and Russia, based on recent data I have compiled. 2. AIDS-related laws at present in various countries. (1) Comparison of major laws (17 countries) including 1) patient (17 countries) and infected person (13 countries) notification, 2) protection of privacy (9 countries), 3) prohibiting infected person discrimination (3 countries) and 4) other matters including restraint on behavior to spread infection (6 countries). (2) Entry laws from foreign country (10 countries) applicable to patient and infected person for 1) entry (3 countries) and 2) long period of stay (8 countries). 3. Present countermeasures to AIDS. (1) Data for 8 countries including Japan, U.S.A. U.K., France, Germany and three eastern European countries with regard to 1) budgets, 2) examinations, 3) medical care, 4) consultation and guidance and 5) education. I shall also discuss the following 2 countermeasures in Japan. I have proposed to the Diet: 1) Examination to detect HIV-antibodies in donated blood. This measure is present in effect since Nov. 1st, 1986, as a result of my proposal made to the Diet on March 14th, 1986. 2) For person infected by transfusion of the blood products without heat treatment, I proposed that expenses should be defrayed according to the CD4 level at either CD4 < or = 200 or CD4 < or = 500. (2) Present situation in eastern European countries. Common features are as follows: 1) Infected person and patient are quarantined if they request, since they know their condition which was disclosed based on data from past mass screening test under communism. 2) At present infected persons are few in number. 3) This number will rapidly increase with greater active interchange with western countries following elimination of the Berlin Wall. 4) AIDS countermeasures such as blood and blood products examinations are inadequate due to insufficient funds. In Bulgaria, the government has conducted AIDS tests on more than half the population and in Romania, there is the tragic situation. (3) Guidelines for WHO-ILO countermeasures to AIDS at work places. 4. Present situation in research. The development of effective medicines and vaccines is the primary objective of AIDS research. Research programs may be enumerated as follows; 1) In the U.S.A., NIH and CDC are major organizations which lead research around the world. The major objective is synthetic medicine. 2) In U.K., the development of vaccines for monkey and cat is being sought. 3) In China, herb medicine is administrated to patients in Un-nan-sho where AIDS patients are quite numerous. 4) In Japan, a recombinant vaccine is being sought through use of BCG, vaccinia viruses and the like. 5. Topics related to AIDS include 1) informed consent to be treated by a AIDS-infected doctor, 2) suits against doctors who fail to make infected person known infection and 3) government control laws for AIDS in Russia.

  8. Performance Characteristics of qPCR Assays Targeting Human- and Ruminant-Associated Bacteroidetes for Microbial Source Tracking across Sixteen Countries on Six Continents

    PubMed Central

    2013-01-01

    Numerous quantitative PCR assays for microbial fecal source tracking (MST) have been developed and evaluated in recent years. Widespread application has been hindered by a lack of knowledge regarding the geographical stability and hence applicability of such methods beyond the regional level. This study assessed the performance of five previously reported quantitative PCR assays targeting human-, cattle-, or ruminant-associated Bacteroidetes populations on 280 human and animal fecal samples from 16 countries across six continents. The tested cattle-associated markers were shown to be ruminant-associated. The quantitative distributions of marker concentrations in target and nontarget samples proved to be essential for the assessment of assay performance and were used to establish a new metric for quantitative source-specificity. In general, this study demonstrates that stable target populations required for marker-based MST occur around the globe. Ruminant-associated marker concentrations were strongly correlated with total intestinal Bacteroidetes populations and with each other, indicating that the detected ruminant-associated populations seem to be part of the intestinal core microbiome of ruminants worldwide. Consequently tested ruminant-targeted assays appear to be suitable quantitative MST tools beyond the regional level while the targeted human-associated populations seem to be less prevalent and stable, suggesting potential for improvements in human-targeted methods. PMID:23755882

  9. Multidimensional approach to invasive species prevention.

    PubMed

    Briski, Elizabeta; Allinger, Lisa E; Balcer, Mary; Cangelosi, Allegra; Fanberg, Lana; Markee, Tom P; Mays, Nicole; Polkinghorne, Christine N; Prihoda, Kelsey R; Reavie, Euan D; Regan, Deanna H; Reid, Donald M; Saillard, Heidi J; Schwerdt, Tyler; Schaefer, Heidi; TenEyck, Matthew; Wiley, Chris J; Bailey, Sarah A

    2013-02-05

    Nonindigenous species (NIS) cause global biotic homogenization and extinctions, with commercial shipping being a leading vector for spread of aquatic NIS. To reduce transport of NIS by ships, regulations requiring ballast water exchange (BWE) have been implemented by numerous countries. BWE appears to effectively reduce risk for freshwater ports, but provides only moderate protection of marine ports. In the near future, ships may be required to undertake ballast water treatment (BWT) to meet numeric performance standards, and BWE may be phased out of use. However, there are concerns that BWT systems may not operate reliably in fresh or turbid water, or both. Consequently, it has been proposed that BWE could be used in combination with BWT to maximize the positive benefits of both management strategies for protection of freshwater ports. We compared the biological efficacy of "BWE plus BWT" against "BWT alone" at a ballast water treatment experimental test facility. Our comparative evaluation showed that even though BWT alone significantly reduced abundances of all tested organism groups except total heterotrophic bacteria, the BWE plus BWT strategy significantly reduced abundances for all groups and furthermore resulted in significantly lower abundances of most groups when compared to BWT alone. Our study clearly demonstrates potential benefits of combining BWE with BWT to reduce invasion risk of freshwater organisms transported in ships' ballast water, and it should be of interest to policy makers and environmental managers.

  10. Numerical Simulation of Selecting Model Scale of Cable in Wind Tunnel Test

    NASA Astrophysics Data System (ADS)

    Huang, Yifeng; Yang, Jixin

    The numerical simulation method based on computational Fluid Dynamics (CFD) provides a possible alternative means of physical wind tunnel test. Firstly, the correctness of the numerical simulation method is validated by one certain example. In order to select the minimum length of the cable as to a certain diameter in the numerical wind tunnel tests, the numerical wind tunnel tests based on CFD are carried out on the cables with several different length-diameter ratios (L/D). The results show that, when the L/D reaches to 18, the drag coefficient is stable essentially.

  11. Integrated studies for automobile wastes management in developing countries; in the concept of environmentally friendly mechanic village.

    PubMed

    Nwachukwu, Michael Amamechi; Feng, Huan; Achilike, Kennedy

    2011-07-01

    More cities in developing countries now consider mechanic village (MV) as superior to the city wide auto-workshop practice following the increasing influx of used or waste automobile from industrialized nations. This is because of the numerous advantages of the mechanic village concept as a capacity building, and in poverty alleviation. Nevertheless, mechanic villages are poorly developed with no waste management plan. They are now identified with severe to excessive heavy metal soil pollution, causing ecological and public health hazards. This paper has a wider explanation of what it takes for a mechanic village to be environmentally friendly based on spectroscopic analysis and physical measurements conducted in three MVs. Heavy metal concentrations (mg kg( -1)) above background levels in the upper 100 cm soil profiles of the Okigwe, the Orji, and the Nekede MVs in the Imo River basin collectively range 748-70,606 for Fe; 99-1,090 for Pb; 186-600 for Mn; 102-1,001 for Cu; 8-23 for Cd; 4-27 for Cr; and 3-10 for Ni. The most abundant metals of environmental concerns are Pb, Mn, and Cu, in the order of Pb > Mn > Cu. Three-phase storm water treatment, emission testing, minimum safe farming distance (350 m), extended producer responsibility for disposal or recycling of used motor oil, phyto-remediation using local plants, groundwater monitoring wells, and continuous education of mechanics are recommended. Exporters of waste automobiles to developing countries and the United Nations may assist developing countries in establishing environmentally friendly MVs.

  12. A Collaborative Effort Between Caribbean States for Tsunami Numerical Modeling: Case Study CaribeWave15

    NASA Astrophysics Data System (ADS)

    Chacón-Barrantes, Silvia; López-Venegas, Alberto; Sánchez-Escobar, Rónald; Luque-Vergara, Néstor

    2018-04-01

    Historical records have shown that tsunami have affected the Caribbean region in the past. However infrequent, recent studies have demonstrated that they pose a latent hazard for countries within this basin. The Hazard Assessment Working Group of the ICG/CARIBE-EWS (Intergovernmental Coordination Group of the Early Warning System for Tsunamis and Other Coastal Threats for the Caribbean Sea and Adjacent Regions) of IOC/UNESCO has a modeling subgroup, which seeks to develop a modeling platform to assess the effects of possible tsunami sources within the basin. The CaribeWave tsunami exercise is carried out annually in the Caribbean region to increase awareness and test tsunami preparedness of countries within the basin. In this study we present results of tsunami inundation using the CaribeWave15 exercise scenario for four selected locations within the Caribbean basin (Colombia, Costa Rica, Panamá and Puerto Rico), performed by tsunami modeling researchers from those selected countries. The purpose of this study was to provide the states with additional results for the exercise. The results obtained here were compared to co-seismic deformation and tsunami heights within the basin (energy plots) provided for the exercise to assess the performance of the decision support tools distributed by PTWC (Pacific Tsunami Warning Center), the tsunami service provider for the Caribbean basin. However, comparison of coastal tsunami heights was not possible, due to inconsistencies between the provided fault parameters and the modeling results within the provided exercise products. Still, the modeling performed here allowed to analyze tsunami characteristics at the mentioned states from sources within the North Panamá Deformed Belt. The occurrence of a tsunami in the Caribbean may affect several countries because a great variety of them share coastal zones in this basin. Therefore, collaborative efforts similar to the one presented in this study, particularly between neighboring countries, are critical to assess tsunami hazard and increase preparedness within the countries.

  13. A Collaborative Effort Between Caribbean States for Tsunami Numerical Modeling: Case Study CaribeWave15

    NASA Astrophysics Data System (ADS)

    Chacón-Barrantes, Silvia; López-Venegas, Alberto; Sánchez-Escobar, Rónald; Luque-Vergara, Néstor

    2017-10-01

    Historical records have shown that tsunami have affected the Caribbean region in the past. However infrequent, recent studies have demonstrated that they pose a latent hazard for countries within this basin. The Hazard Assessment Working Group of the ICG/CARIBE-EWS (Intergovernmental Coordination Group of the Early Warning System for Tsunamis and Other Coastal Threats for the Caribbean Sea and Adjacent Regions) of IOC/UNESCO has a modeling subgroup, which seeks to develop a modeling platform to assess the effects of possible tsunami sources within the basin. The CaribeWave tsunami exercise is carried out annually in the Caribbean region to increase awareness and test tsunami preparedness of countries within the basin. In this study we present results of tsunami inundation using the CaribeWave15 exercise scenario for four selected locations within the Caribbean basin (Colombia, Costa Rica, Panamá and Puerto Rico), performed by tsunami modeling researchers from those selected countries. The purpose of this study was to provide the states with additional results for the exercise. The results obtained here were compared to co-seismic deformation and tsunami heights within the basin (energy plots) provided for the exercise to assess the performance of the decision support tools distributed by PTWC (Pacific Tsunami Warning Center), the tsunami service provider for the Caribbean basin. However, comparison of coastal tsunami heights was not possible, due to inconsistencies between the provided fault parameters and the modeling results within the provided exercise products. Still, the modeling performed here allowed to analyze tsunami characteristics at the mentioned states from sources within the North Panamá Deformed Belt. The occurrence of a tsunami in the Caribbean may affect several countries because a great variety of them share coastal zones in this basin. Therefore, collaborative efforts similar to the one presented in this study, particularly between neighboring countries, are critical to assess tsunami hazard and increase preparedness within the countries.

  14. A focus on the consumer: social marketing for change.

    PubMed

    Lucaire, L E

    1985-01-01

    Social marketing is the application of commercial marketing principles to advance a social cause, issue, behavior, product, or service. Social marketing has added a framework to social efforts that heretofore lacked organization and has inspired projects that otherwise might never have been initiated. In the US, social marketing techniques have been particularly successful in the health field. Although advertising and other communications are central to social marketing, the discipline also depends upon other elements of what is termed the marketing mix: product, price, place, and promotion. Social marketing is a cyclical process involving 6 steps: analysis; planning; development, testing, and refining elements of the plan; implementation; assessment of in-market effectiveness; and feedback. In developing countries, health has similarly been the greatest beneficiary to date of applied social marketing techniques. Family planning programs and oral rehydration therapy (ORT) projects have used social marketing techniques effectively in numerous developing countries. Social marketing has been even more widely applied in the sale of contraceptives in developing countries. Contraceptive social marketing (CSM) programs are well established in Bangladesh, Sri Lanka, India, Thailand, Nepal, Colombia, El Salvador, Jamaica, Mexico, and Egypt. More recently programs have been established in Honduras, Guatemala, Barbados, St. Vincent, and St. Lucia. SOMARC (Social Marketing for Change) is a project funded by the US Agency for International Development (AID) and is working with existing CSM programs and helping to launch new CSM programs. CSM programs are successfully functioning as legitimate marketing organizations in developing countries and are using local private sector resources in the process. Program results are encouraging. Social marketing requires both experience and sensitivity to local conditions. Many developing countries now have their own marketing resources. Local private sector advertising and marketing agencies are helping public and private sector programs. In countries where local resources are scarce, AID has created several programs to provide technical assistance in social marketing.

  15. Measuring mechanisms for quality assurance in primary care systems in transition: test of a new instrument in Slovenia and Uzbekistan.

    PubMed

    Kringos, Dionne Sofia; Boerma, Wienke; Pellny, Martina

    2009-01-01

    This World Health Organization (WHO) study aimed to develop and field test an instrument to assess the availability of structures and mechanisms for managing quality in primary care in countries in transition. The instrument is based on a literature study, consensus meetings with experts, and observations in these countries. It consists of three parts: a semi-structured questionnaire on national policies and mechanisms; a structured questionnaire for general practitioners (GPs); and a structured questionnaire for use with managers of primary care facilities. The instrument has been field tested in 2007 in Slovenia and Uzbekistan. In Slovenia, leadership on quality improvement was weak and local managers reported few incentives and resources to control quality. There was a lack of external support for quality improvement activities. Availability and use of clinical guidelines for GPs were not optimal. GPs found teamwork and communication with patients inadequate. In Uzbekistan, primary care quality and standards in health centres were extensively regulated and laid down in numerous manuals, instructions and other documents. Managers, however, indicated the need for more financial and non-financial levers for quality improvement and they wanted to know more about modern healthcare management. GPs reported strong involvement in activities such as peer review and clinical audit, and reported frequent use of clinical guidelines. Overall, the information gathered with the provisional instrument has resulted in policy recommendations. At the same time, the pilot resulted in improvements to the instrument. Application of the instrument helps decision makers to identify improvement areas in the infrastructure for managing the quality of primary care.

  16. Acute Heat Stress Induces Differential Gene Expressions in the Testes of a Broiler-Type Strain of Taiwan Country Chickens

    PubMed Central

    Wang, Shih-Han; Cheng, Chuen-Yu; Tang, Pin-Chi; Chen, Chih-Feng; Chen, Hsin-Hsin; Lee, Yen-Pai; Huang, San-Yuan

    2015-01-01

    The expression of testicular genes following acute heat stress has been reported in layer-type roosters, but few similar studies have been conducted on broilers. This study investigated the effect of acute heat stress on the gene expression in the testes of a broiler-type strain of Taiwan country chickens. Roosters were subjected to acute heat stress (38°C) for 4 h, and then exposed to 25°C, with testes collected 0, 2, and 6 h after the cessation of heat stress, using non-heat-stressed roosters as controls (n = 3 roosters per group). The body temperature and respiratory rate increased significantly (p<0.05) during the heat stress. The numbers of apoptotic cells increased 2 h after the acute heat stress (79 ± 7 vs. 322 ± 192, control vs. heat stress; p<0.05), which was earlier than the time of increase in layer-type roosters. Based on a chicken 44 K oligo microarray, 163 genes were found to be expressed significantly different in the testes of the heat-stressed chickens from those of the controls, including genes involved in the response to stimulus, protein metabolism, signal transduction, cell adhesion, transcription, and apoptosis. The mRNA expressions of upregulated genes, including HSP25, HSP90AA1, HSPA2, and LPAR2, and of downregulated genes, including CDH5, CTNNA3, EHF, CIRBP, SLA, and NTF3, were confirmed through quantitative real-time polymerase chain reaction (qRT-PCR). Moreover, numerous transcripts in the testes exhibited distinct expressions between the heat-stressed broiler-type and layer-type chickens. We concluded that the transcriptional responses of testes to acute heat stress may differ between the broiler-type and layer-type roosters. Whether the differential expression patterns associate with the heat-tolerance in the strains require a further exploration. PMID:25932638

  17. Acute heat stress induces differential gene expressions in the testes of a broiler-type strain of Taiwan country chickens.

    PubMed

    Wang, Shih-Han; Cheng, Chuen-Yu; Tang, Pin-Chi; Chen, Chih-Feng; Chen, Hsin-Hsin; Lee, Yen-Pai; Huang, San-Yuan

    2015-01-01

    The expression of testicular genes following acute heat stress has been reported in layer-type roosters, but few similar studies have been conducted on broilers. This study investigated the effect of acute heat stress on the gene expression in the testes of a broiler-type strain of Taiwan country chickens. Roosters were subjected to acute heat stress (38°C) for 4 h, and then exposed to 25°C, with testes collected 0, 2, and 6 h after the cessation of heat stress, using non-heat-stressed roosters as controls (n = 3 roosters per group). The body temperature and respiratory rate increased significantly (p<0.05) during the heat stress. The numbers of apoptotic cells increased 2 h after the acute heat stress (79 ± 7 vs. 322 ± 192, control vs. heat stress; p<0.05), which was earlier than the time of increase in layer-type roosters. Based on a chicken 44 K oligo microarray, 163 genes were found to be expressed significantly different in the testes of the heat-stressed chickens from those of the controls, including genes involved in the response to stimulus, protein metabolism, signal transduction, cell adhesion, transcription, and apoptosis. The mRNA expressions of upregulated genes, including HSP25, HSP90AA1, HSPA2, and LPAR2, and of downregulated genes, including CDH5, CTNNA3, EHF, CIRBP, SLA, and NTF3, were confirmed through quantitative real-time polymerase chain reaction (qRT-PCR). Moreover, numerous transcripts in the testes exhibited distinct expressions between the heat-stressed broiler-type and layer-type chickens. We concluded that the transcriptional responses of testes to acute heat stress may differ between the broiler-type and layer-type roosters. Whether the differential expression patterns associate with the heat-tolerance in the strains require a further exploration.

  18. Alternatives to animal testing: information resources via the Internet and World Wide Web.

    PubMed

    Hakkinen, P J Bert; Green, Dianne K

    2002-04-25

    Many countries, including the United States, Canada, European Union member states, and others, require that a comprehensive search for possible alternatives be completed before beginning some or all research involving animals. Completing comprehensive alternatives searches and keeping current with information associated with alternatives to animal testing is a challenge that will be made easier as people throughout the world gain access to the Internet and World Wide Web. Numerous Internet and World Wide Web resources are available to provide guidance and other information on in vitro and other alternatives to animal testing. A comprehensive Web site is Alternatives to Animal Testing on the Web (Altweb), which serves as an online clearinghouse for resources, information, and news about alternatives to animal testing. Examples of other important Web sites include the joint one for the (US) Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM) and the National Toxicology Program (NTP) Interagency Center for the Evaluation of Alternative Toxicological Methods (NICEATM) and the Norwegian Reference Centre for Laboratory Animal Science and Alternatives (The NORINA database). Internet mailing lists and online access to bulletin boards, discussion areas, newsletters, and journals are other ways to access and share information to stay current with alternatives to animal testing.

  19. Hepatitis B virus burden in developing countries

    PubMed Central

    Zampino, Rosa; Boemio, Adriana; Sagnelli, Caterina; Alessio, Loredana; Adinolfi, Luigi Elio; Sagnelli, Evangelista; Coppola, Nicola

    2015-01-01

    Hepatitis B virus (HBV) infection has shown an intermediate or high endemicity level in low-income countries over the last five decades. In recent years, however, the incidence of acute hepatitis B and the prevalence of hepatitis B surface antigen chronic carriers have decreased in several countries because of the HBV universal vaccination programs started in the nineties. Some countries, however, are still unable to implement these programs, particularly in their hyperendemic rural areas. The diffusion of HBV infection is still wide in several low-income countries where the prevention, management and treatment of HBV infection are a heavy burden for the governments and healthcare authorities. Of note, the information on the HBV epidemiology is scanty in numerous eastern European and Latin-American countries. The studies on molecular epidemiology performed in some countries provide an important contribution for a more comprehensive knowledge of HBV epidemiology, and phylogenetic studies provide information on the impact of recent and older migratory flows. PMID:26576083

  20. Structural Impact of Construction Loads

    DOT National Transportation Integrated Search

    2012-08-01

    Numerous bridge construction accidents have occurred across the country because of construction loadings, which are an underemphasized : topic in many DOT specifications and design manuals. Bridge girders are least stable when they are subjected to c...

  1. Structural Impact of Construction Loads

    DOT National Transportation Integrated Search

    2012-08-01

    Numerous bridge construction accidents have occurred across the country because of construction loadings, which are an underemphasized topic in many DOT specifications and design manuals. Bridge girders are least stable when they are subjected to con...

  2. The multiple mini-interview for selecting medical residents: first experience in the Middle East region.

    PubMed

    Ahmed, Ashraf; Qayed, Khalil Ibrahim; Abdulrahman, Mahera; Tavares, Walter; Rosenfeld, Jack

    2014-08-01

    Numerous studies have shown that multiple mini-interviews (MMI) provides a standard, fair, and more reliable method for assessing applicants. This article presents the first MMI experience for selection of medical residents in the Middle East culture and an Arab country. In 2012, we started using the MMI in interviewing applicants to the residency program of Dubai Health Authority. This interview process consisted of eight, eight-minute structured interview scenarios. Applicants rotated through the stations, each with its own interviewer and scenario. They read the scenario and were requested to discuss the issues with the interviewers. Sociodemographic and station assessment data provided for each applicant were analyzed to determine whether the MMI was a reliable assessment of the non-clinical attributes in the present setting of an Arab country. One hundred and eighty-seven candidates from 27 different countries were interviewed for Dubai Residency Training Program using MMI. They were graduates of 5 medical universities within United Arab Emirates (UAE) and 60 different universities outside UAE. With this applicant's pool, a MMI with eight stations, produced absolute and relative reliability of 0.8 and 0.81, respectively. The person × station interaction contributed 63% of the variance components, the person contributed 34% of the variance components, and the station contributed 2% of the variance components. The MMI has been used in numerous universities in English speaking countries. The MMI evaluates non-clinical attributes and this study provides further evidence for its reliability but in a different country and culture. The MMI offers a fair and more reliable assessment of applicants to medical residency programs. The present data show that this assessment technique applied in a non-western country and Arab culture still produced reliable results.

  3. Validation of numerical model for cook stove using Reynolds averaged Navier-Stokes based solver

    NASA Astrophysics Data System (ADS)

    Islam, Md. Moinul; Hasan, Md. Abdullah Al; Rahman, Md. Mominur; Rahaman, Md. Mashiur

    2017-12-01

    Biomass fired cook stoves, for many years, have been the main cooking appliance for the rural people of developing countries. Several researches have been carried out to the find efficient stoves. In the present study, numerical model of an improved household cook stove is developed to analyze the heat transfer and flow behavior of gas during operation. The numerical model is validated with the experimental results. Computation of the numerical model is executed the using non-premixed combustion model. Reynold's averaged Navier-Stokes (RaNS) equation along with the κ - ɛ model governed the turbulent flow associated within the computed domain. The computational results are in well agreement with the experiment. Developed numerical model can be used to predict the effect of different biomasses on the efficiency of the cook stove.

  4. A Comparative Study on the Lot Release Systems for Vaccines as of 2016.

    PubMed

    Fujita, Kentaro; Naito, Seishiro; Ochiai, Masaki; Konda, Toshifumi; Kato, Atsushi

    2017-09-25

    Many countries have already established their own vaccine lot release system that is designed for each country's situation: while the World Health Organization promotes for the convergence of these regulatory systems so that vaccines of assured quality are provided globally. We conducted a questionnaire-based investigation of the lot release systems for vaccines in 7 countries and 2 regions. We found that a review of the summary protocol by the National Regulatory Authorities was commonly applied for the independent lot release of vaccines, however, we also noted some diversity between countries, especially in regard to the testing policy. Some countries and regions, including Japan, regularly tested every lot of vaccines, whereas the frequency of these tests was reduced in other countries and regions as determined based on the risk assessment of these products. Test items selected for the lot release varied among the countries or regions investigated, although there was a tendency to prioritize the potency tests. An understanding of the lot release policy may contribute to improving and harmonizing the lot release system globally in the future.

  5. Groundwater arsenic contamination throughout China.

    PubMed

    Rodríguez-Lado, Luis; Sun, Guifan; Berg, Michael; Zhang, Qiang; Xue, Hanbin; Zheng, Quanmei; Johnson, C Annette

    2013-08-23

    Arsenic-contaminated groundwater used for drinking in China is a health threat that was first recognized in the 1960s. However, because of the sheer size of the country, millions of groundwater wells remain to be tested in order to determine the magnitude of the problem. We developed a statistical risk model that classifies safe and unsafe areas with respect to geogenic arsenic contamination in China, using the threshold of 10 micrograms per liter, the World Health Organization guideline and current Chinese standard for drinking water. We estimate that 19.6 million people are at risk of being affected by the consumption of arsenic-contaminated groundwater. Although the results must be confirmed with additional field measurements, our risk model identifies numerous arsenic-affected areas and highlights the potential magnitude of this health threat in China.

  6. International Spring and Summer Festivals. Projects and Patterns for Holiday Gifts, Greetings, Ornaments, Decorations, and Classroom Displays. A Good Apple Seasonal Idea/Activity Book for Grades 1-6.

    ERIC Educational Resources Information Center

    Barr, Marilynn G.

    This seasonal idea/activity book for grades 1-6 features interesting facts on the origins of traditions and customs of spring and summer festivals from around the world. There are numerous hands-on art activities, a map of each country or continent of the activity's origin, and a brief explanation of each tradition. Areas and countries of the…

  7. [Urbanization in tropical countries].

    PubMed

    Amat-Roze, J M

    1983-01-01

    Rural populations are still the most numerous in tropical countries. But we can witness an unprecedent process of urbanization. However the dynamics of the phenomenon differs greatly in different countries and in different towns. As a matter of fact, the greatest overcrowded metropolis attract the greatest part of the migrants from rural areas; the attractive factors are multifarious and universal. This not easily controllable trend seems to be irreversible. The migrant farmers will generally find a job within the informed economic sector. The zones of spontaneous and precarious settlement are often their first environmental living conditions. Some of these unhealthy dwelling areas are subject to development plans; some of them being extremely well designed.

  8. Public awareness and attitudes towards epilepsy in Tehran, Iran.

    PubMed

    Ghanean, Helia; Nojomi, Marzieh; Jacobsson, Lars

    2013-12-05

    Epilepsy is a prototypical, stigmatised disorder. Numerous studies have been conducted regarding the public perception of epilepsy, but they are primarily from high-income western countries; few studies have taken place in low- to middle-income countries with a traditional culture and a religious orientation. The public knowledge and attitudes towards epilepsy in Tehran, Iran, is studied. A survey of 800 subjects ranging from 18 to 85 years was randomly chosen from households in Tehran in 2009. The questionnaire used was based on the Caveness and Gallup's studies conducted in the United States in 1949 and it has been used in numerous similar studies all over the world. The mean age of the participants was 37.5 years and 46.7% were female. Pearson's Chi-squared test was used for subgroup analyses. The majority of subjects cited brain disorders as a cause of epilepsy, while 17% indicated the will of God as the cause. Most individuals were willing to work with a person with epilepsy, allow their children to play with a child with epilepsy, and allow people with epilepsy to use public transportation (78-82%). However, only 28% were willing to accept the marriage of a family member to someone with epilepsy. The knowledge and attitudes towards epilepsy are similar to those in Europe, with the exception of a much lower acceptance regarding marriage to a person with epilepsy. However, the low acceptance for marrying someone with epilepsy reveals the remaining misconceptions about the nature of epilepsy in Iran, despite the high educational level in the studied population. Therefore, informational efforts must be employed to change the perception of epilepsy.

  9. Consistency assessment with global and bridging development strategies in emerging markets.

    PubMed

    Li, Gang; Chen, Josh; Quan, Hui; Shentu, Yue

    2013-11-01

    Global trial strategy with the participation of all major regions including countries from emerging markets surely increases new drug development efficiency. Nevertheless, there are circumstances in which some countries in emerging markets cannot join the original global trial. To evaluate the extrapolability of the original trial results to a new country, a bridging trial in the country has to be conducted. In this paper, we first evaluate the efficiency loss of the bridging trial strategy compared to that of the global trial strategy as a function of between-study variability from consistency assessment perspective. The provided evidence should encourage countries in emerging markets to make a greater effort to participate in the original global trial. We then discuss sample size requirement for desired assurance probability for consistency assessment based on various approaches for both global and bridging trial strategies. Examples are presented for numerical demonstration and comparisons. Copyright © 2013 Elsevier Inc. All rights reserved.

  10. The effects of conduit length and acoustic velocity on conduit resonance: Implications for low-frequency events

    NASA Astrophysics Data System (ADS)

    Sturton, Susan; Neuberg, Jürgen

    2006-03-01

    Low-frequency seismic events at volcanoes are modelled as the seismic wavefield from a magma-filled conduit embedded in a solid country rock using a finite difference method. The effects of varying the conduit length and the impedance contrast between the magma and the country rock are examined, generating a range of possible signals. Short-windowed spectrograms are used to look at the time-frequency relationships within the events in detail, and some of the possible variations are identified using a series of schematic spectrograms. The numerical results are compared to examples of observed seismic data from Soufrière Hills Volcano, Montserrat. While the spectra of the observed events are often different to the spectra of the numerical results, the spectrograms have similar features and show that the low-frequency events from Montserrat are composed of discrete subevents.

  11. Promises and Pitfalls of Anchoring Vignettes in Health Survey Research

    PubMed Central

    Verdes-Tennant, Emese; McEniry, Mary; Ispány, Márton

    2016-01-01

    Data harmonization is a topic of growing importance to demographers, who increasingly conduct domestic or international comparative research. Many self-reported survey items cannot be directly compared across demographic groups or countries because these groups differ in how they use subjective response categories. Anchoring vignettes, already appearing in numerous surveys worldwide, promise to overcome this problem. However, many anchoring vignettes have not been formally evaluated for adherence to the key measurement assumptions of vignette equivalence and response consistency. This article tests these assumptions in some of the most widely fielded anchoring vignettes in the world: the health vignettes in the World Health Organization (WHO) Study on Global AGEing and Adult Health (SAGE) and World Health Survey (WHS) (representing 10 countries; n = 52,388), as well as similar vignettes in the Health and Retirement Study (HRS) (n = 4,528). Findings are encouraging regarding adherence to response consistency, but reveal substantial violations of vignette equivalence both cross-nationally and across socioeconomic groups. That is, members of different sociocultural groups appear to interpret vignettes as depicting fundamentally different levels of health. The evaluated anchoring vignettes do not fulfill their promise of providing interpersonally comparable measures of health. Recommendations for improving future implementations of vignettes are discussed. PMID:26335547

  12. Die philippinische Diaspora - Migration als Bevölkerungsventil und lokale Entwicklungswirkungen

    NASA Astrophysics Data System (ADS)

    Haub, Olaf

    2018-03-01

    According to the Commission on Filipinos Overseas (CFO, 2013), the Philippine diaspora consists of about 10 million Filipinos, which is about 10% of the total population. Of these, just under half are temporary migrant workers (OFWs, Oversea Filipino Workers), with most OFWs working in the Gulf States. With the booming oil industry in the 70s in the Gulf, numerous job opportunities were created at that time. This started the massive migration of Filipino workers to the Gulf States as well as the support of labour migration by the Philippine government. In the meantime, highly qualified workers and professionals from the Philippines are to be found in almost every country and are in demand in numerous fields. The remittances of the OFWs amount to nearly 10% of the gross domestic product and thus make a significant contribution not only to the macroeconomic development but also to poverty alleviation in the country. The coordination and support of the Philippine labour migration has been steadily improving since the 1970s and evolved into a successful system that supports the economy and reduces unemployment. For the employing host countries, the Philippines have long become an indispensable source of labour.

  13. Die philippinische Diaspora. Migration als Bevölkerungsventil und lokale Entwicklungswirkungen

    NASA Astrophysics Data System (ADS)

    Haub, Olaf

    2018-04-01

    According to the Commission on Filipinos Overseas (CFO, 2013), the Philippine diaspora consists of about 10 million Filipinos, which is about 10% of the total population. Of these, just under half are temporary migrant workers (OFWs, Oversea Filipino Workers), with most OFWs working in the Gulf States. With the booming oil industry in the 70s in the Gulf, numerous job opportunities were created at that time. This started the massive migration of Filipino workers to the Gulf States as well as the support of labour migration by the Philippine government. In the meantime, highly qualified workers and professionals from the Philippines are to be found in almost every country and are in demand in numerous fields. The remittances of the OFWs amount to nearly 10% of the gross domestic product and thus make a significant contribution not only to the macroeconomic development but also to poverty alleviation in the country. The coordination and support of the Philippine labour migration has been steadily improving since the 1970s and evolved into a successful system that supports the economy and reduces unemployment. For the employing host countries, the Philippines have long become an indispensable source of labour.

  14. Supporting Reporting: On the Positive Effects of Text- and Video-Based Awareness Material on Responsible Journalistic Suicide News Writing.

    PubMed

    Scherr, Sebastian; Arendt, Florian; Schäfer, Markus

    2017-01-01

    Suicide is a global public health problem. Media impact on suicide is well confirmed and there are several recommendations on how media should and should not report on suicide to minimize the risk of copycat behavior. Those media guidelines have been developed to improve responsible reporting on suicide (RRS). Although such guidelines are used in several countries, we lack empirical evidence on their causal effect on actual journalistic news writing. We conducted an experiment with journalism students (N = 78) in Germany in which we tested whether exposure to awareness material promoting RRS influences news writing. As a supplement to the widely used text-based material, we tested the impact of a video in which a suicide expert presents the guidelines. A video was used as a supplement to text partly due to its potential benefit for prevention efforts over the Internet. We chose a low-budget production process allowing easy reproduction in different countries by local suicide experts. In the experiment, participants were either exposed to written, audio-visual, or no awareness material. Afterwards, participants read numerous facts of an ostensible suicide event and were asked to write a factual suicide news story based on these facts. Analyses indicate that awareness material exposure helped to improve RRS with the awareness video showing the strongest effects. We recommend that suicide prevention should use instructive awareness videos about RRS complementary to text-based awareness material.

  15. [Book review] Birds in Europe: Population estimates, trends and conservation status

    USGS Publications Warehouse

    Peterjohn, Bruce G.

    2006-01-01

    Effective bird conservation requires knowledge of distribution, relative abundance, and population trends at multiple geographic scales. Obtaining this information for a continental avifauna poses considerable challenges, especially in Europe with its 52 countries, numerous languages and cultures, and disparate resources available for monitoring bird populations within each country. Synthesizing the available information on the status and trends of all European birds into a single volume is an enormous yet essential task necessary to direct bird conservation activities across the continent.

  16. Assessing the impact of travel restrictions on international spread of the 2014 West African Ebola epidemic

    PubMed Central

    Poletto, Chiara; Gomes, Marcelo F. C.; Piontti, Ana Pastore y; Rossi, Luca; Bioglio, Livio; Chao, Dennis L.; Longini, Ira M.; Halloran, M. Elizabeth; Colizza, Vittoria; Vespignani, Alessandro

    2015-01-01

    The quick spread of an Ebola outbreak in West Africa has led a number of countries and airline companies to issue travel bans to the affected areas. Considering data up to 31 Aug 2014, we assess the impact of the resulting traffic reductions with detailed numerical simulations of the international spread of the epidemic. Traffic reductions are shown to delay by only a few weeks the risk that the outbreak extends to new countries. PMID:25358040

  17. Mountain bicycle frame testing as an example of practical implementation of hybrid simulation using RTFEM

    NASA Astrophysics Data System (ADS)

    Mucha, Waldemar; Kuś, Wacław

    2018-01-01

    The paper presents a practical implementation of hybrid simulation using Real Time Finite Element Method (RTFEM). Hybrid simulation is a technique for investigating dynamic material and structural properties of mechanical systems by performing numerical analysis and experiment at the same time. It applies to mechanical systems with elements too difficult or impossible to model numerically. These elements are tested experimentally, while the rest of the system is simulated numerically. Data between the experiment and numerical simulation are exchanged in real time. Authors use Finite Element Method to perform the numerical simulation. The following paper presents the general algorithm for hybrid simulation using RTFEM and possible improvements of the algorithm for computation time reduction developed by the authors. The paper focuses on practical implementation of presented methods, which involves testing of a mountain bicycle frame, where the shock absorber is tested experimentally while the rest of the frame is simulated numerically.

  18. Organ trafficking: global solutions for a global problem.

    PubMed

    Jafar, Tazeen H

    2009-12-01

    The organ trafficking market is on the rise worldwide. Numerous unfortunate stories of networks of brokers, physicians, and hospitals engaged in illegal trade have been featured in high-profile media. The profitable enterprises facilitating these unregulated services exploit the poor in underresourced countries and offer substandard medical care with unacceptable outcomes to the rich recipients. Despite efforts to boost altruistic organ donation and resolutions to curb transplant tourism, their implementation has been compromised. At the same time, the worldwide escalation in the number of patients with kidney failure coupled with a shortage in the supply of organs continues to fuel this trade. Thus, measures to enhance the donor pool in well-resourced countries to meet their own needs will act as a strong deterrent to the proliferation of transplant tourism in impoverished nations. Regulated schemes that include reimbursement for removing potential disincentives to organ donation and ensure the long-term safety of donors and their families are likely to increase living donations. Such socially responsible programs should be tested in both developed and developing countries for their own populations. It also is vital that developing countries establish a regulated, standardized, and ethical system of organ procurement; create awareness in physicians and the public; upgrade facilities and standardize medical care; and enforce legislation for transplantation. The World Health Organization, National Kidney Foundation, and international transplant and nephrology societies can have an instrumental role in facilitating initiatives in these critical areas. There should be clearly defined codes of conduct for health care facilities and professionals' roles in unregulated paid organ donations and transplants. Ultimately, physicians and transplant surgeons have the responsibility to ensure to the best of their ability that the organs they transplant were obtained upholding the highest standards of ethics.

  19. Leapfrog diagnostics: Demonstration of a broad spectrum pathogen identification platform in a resource-limited setting

    PubMed Central

    2012-01-01

    Background Resource-limited tropical countries are home to numerous infectious pathogens of both human and zoonotic origin. A capability for early detection to allow rapid outbreak containment and prevent spread to non-endemic regions is severely impaired by inadequate diagnostic laboratory capacity, the absence of a “cold chain” and the lack of highly trained personnel. Building up detection capacity in these countries by direct replication of the systems existing in developed countries is not a feasible approach and instead requires “leapfrogging” to the deployment of the newest diagnostic systems that do not have the infrastructure requirements of systems used in developed countries. Methods A laboratory for molecular diagnostics of infectious agents was established in Bo, Sierra Leone with a hybrid solar/diesel/battery system to ensure stable power supply and a satellite modem to enable efficient communication. An array of room temperature stabilization and refrigeration technologies for reliable transport and storage of reagents and biological samples were also tested to ensure sustainable laboratory supplies for diagnostic assays. Results The laboratory demonstrated its operational proficiency by conducting an investigation of a suspected avian influenza outbreak at a commercial poultry farm at Bo using broad range resequencing microarrays and real time RT-PCR. The results of the investigation excluded influenza viruses as a possible cause of the outbreak and indicated a link between the outbreak and the presence of Klebsiella pneumoniae. Conclusions This study demonstrated that by application of a carefully selected set of technologies and sufficient personnel training, it is feasible to deploy and effectively use a broad-range infectious pathogen detection technology in a severely resource-limited setting. PMID:22759725

  20. Test Selection, Adaptation, and Evaluation: A Systematic Approach to Assess Nutritional Influences on Child Development in Developing Countries

    ERIC Educational Resources Information Center

    Prado, Elizabeth L.; Hartini, Sri; Rahmawati, Atik; Ismayani, Elfa; Hidayati, Astri; Hikmah, Nurul; Muadz, Husni; Apriatni, Mandri S.; Ullman, Michael T.; Shankar, Anuraj H.; Alcock, Katherine J.

    2010-01-01

    Background: Evaluating the impact of nutrition interventions on developmental outcomes in developing countries can be challenging since most assessment tests have been produced in and for developed country settings. Such tests may not be valid measures of children's abilities when used in a new context. Aims: We present several principles for the…

  1. Reducing stillbirths: screening and monitoring during pregnancy and labour

    PubMed Central

    Haws, Rachel A; Yakoob, Mohammad Yawar; Soomro, Tanya; Menezes, Esme V; Darmstadt, Gary L; Bhutta, Zulfiqar A

    2009-01-01

    Background Screening and monitoring in pregnancy are strategies used by healthcare providers to identify high-risk pregnancies so that they can provide more targeted and appropriate treatment and follow-up care, and to monitor fetal well-being in both low- and high-risk pregnancies. The use of many of these techniques is controversial and their ability to detect fetal compromise often unknown. Theoretically, appropriate management of maternal and fetal risk factors and complications that are detected in pregnancy and labour could prevent a large proportion of the world's 3.2 million estimated annual stillbirths, as well as minimise maternal and neonatal morbidity and mortality. Methods The fourth in a series of papers assessing the evidence base for prevention of stillbirths, this paper reviews available published evidence for the impact of 14 screening and monitoring interventions in pregnancy on stillbirth, including identification and management of high-risk pregnancies, advanced monitoring techniques, and monitoring of labour. Using broad and specific strategies to search PubMed and the Cochrane Library, we identified 221 relevant reviews and studies testing screening and monitoring interventions during the antenatal and intrapartum periods and reporting stillbirth or perinatal mortality as an outcome. Results We found a dearth of rigorous evidence of direct impact of any of these screening procedures and interventions on stillbirth incidence. Observational studies testing some interventions, including fetal movement monitoring and Doppler monitoring, showed some evidence of impact on stillbirths in selected high-risk populations, but require larger rigourous trials to confirm impact. Other interventions, such as amniotic fluid assessment for oligohydramnios, appear predictive of stillbirth risk, but studies are lacking which assess the impact on perinatal mortality of subsequent intervention based on test findings. Few rigorous studies of cardiotocography have reported stillbirth outcomes, but steep declines in stillbirth rates have been observed in high-income settings such as the U.S., where cardiotocography is used in conjunction with Caesarean section for fetal distress. Conclusion There are numerous research gaps and large, adequately controlled trials are still needed for most of the interventions we considered. The impact of monitoring interventions on stillbirth relies on use of effective and timely intervention should problems be detected. Numerous studies indicated that positive tests were associated with increased perinatal mortality, but while some tests had good sensitivity in detecting distress, false-positive rates were high for most tests, and questions remain about optimal timing, frequency, and implications of testing. Few studies included assessments of impact of subsequent intervention needed before recommending particular monitoring strategies as a means to decrease stillbirth incidence. In high-income countries such as the US, observational evidence suggests that widespread use of cardiotocography with Caesarean section for fetal distress has led to significant declines in stillbirth rates. Efforts to increase availability of Caesarean section in low-/middle-income countries should be coupled with intrapartum monitoring technologies where resources and provider skills permit. PMID:19426468

  2. A review on the prevalence and measurement of elder abuse in the community.

    PubMed

    Sooryanarayana, Rajini; Choo, Wan-Yuen; Hairi, Noran N

    2013-10-01

    Aging is a rising phenomenon globally and elder abuse is becoming increasingly recognized as a health and social problem. This review aimed to identify the prevalence of elder abuse in community settings, and discuss issues regarding measurement tools and strategies to measure elderly abuse by systematically reviewing all community-based studies conducted worldwide. Articles on elder abuse from 1990 to 2011 were reviewed. A total of 1,832 articles referring to elders residing at home either in their own or at relatives' houses were searched via CINAHL and MEDLINE electronic databases, in addition to a hand search of the latest articles in geriatric textbooks and screening references, choosing a total of 26 articles for review. Highest prevalence was reported in developed countries, with Spain having 44.6% overall prevalence of suspicion of abuse and developing countries exhibiting lower estimates, from 13.5% to 28.8%. Physical abuse was among the least encountered, with psychological abuse and financial exploitation being the most common types of maltreatment reported. To date, there is no single gold standard test to ascertain abuse, with numerous tools and different methods employed in various studies, coupled with varying definitions of thresholds for age. Current evidences show that elder abuse is a common problem in both developed and developing countries. It is important that social, health care, and legal systems take these findings into consideration in screening for abuse or reforming existing services to protect the health and welfare of the elderly.

  3. Estimating the value of a Country's built assets: investment-based exposure modelling for global risk assessment

    NASA Astrophysics Data System (ADS)

    Daniell, James; Pomonis, Antonios; Gunasekera, Rashmin; Ishizawa, Oscar; Gaspari, Maria; Lu, Xijie; Aubrecht, Christoph; Ungar, Joachim

    2017-04-01

    In order to quantify disaster risk, there is a demand and need for determining consistent and reliable economic value of built assets at national or sub national level exposed to natural hazards. The value of the built stock in the context of a city or a country is critical for risk modelling applications as it allows for the upper bound in potential losses to be established. Under the World Bank probabilistic disaster risk assessment - Country Disaster Risk Profiles (CDRP) Program and rapid post-disaster loss analyses in CATDAT, key methodologies have been developed that quantify the asset exposure of a country. In this study, we assess the complementary methods determining value of building stock through capital investment data vs aggregated ground up values based on built area and unit cost of construction analyses. Different approaches to modelling exposure around the world, have resulted in estimated values of built assets of some countries differing by order(s) of magnitude. Using the aforementioned methodology of comparing investment data based capital stock and bottom-up unit cost of construction values per square meter of assets; a suitable range of capital stock estimates for built assets have been created. A blind test format was undertaken to compare the two types of approaches from top-down (investment) and bottom-up (construction cost per unit), In many cases, census data, demographic, engineering and construction cost data are key for bottom-up calculations from previous years. Similarly for the top-down investment approach, distributed GFCF (Gross Fixed Capital Formation) data is also required. Over the past few years, numerous studies have been undertaken through the World Bank Caribbean and Central America disaster risk assessment program adopting this methodology initially developed by Gunasekera et al. (2015). The range of values of the building stock is tested for around 15 countries. In addition, three types of costs - Reconstruction cost (building back to the standard required by building codes); Replacement cost (gross capital stock) and Book value (net capital stock - depreciated value of assets) are discussed and the differences in methodologies assessed. We then examine historical costs (reconstruction and replacement) and losses (book value) of natural disasters versus this upper bound of capital stock in various locations to examine the impact of a reasonable capital stock estimate. It is found that some historic loss estimates in publications are not reasonable given the value of assets at the time of the event. This has applications for quantitative disaster risk assessment and development of country disaster risk profiles, economic analyses and benchmarking upper loss limits of built assets damaged due to natural hazards.

  4. Indicators of international remote sensing activities

    NASA Technical Reports Server (NTRS)

    Spann, G. W.

    1977-01-01

    The extent of worldwide remote sensing activities, including the use of satellite and high/medium altitude aircraft data was studied. Data were obtained from numerous individuals and organizations with international remote sensing responsibilities. Indicators were selected to evaluate the nature and scope of remote sensing activities in each country. These indicators ranged from attendance at remote sensing workshops and training courses to the establishment of earth resources satellite ground stations and plans for the launch of earth resources satellites. Results indicate that this technology constitutes a rapidly increasing component of environmental, land use, and natural resources investigations in many countries, and most of these countries rely on the LANDSAT satellites for a major portion of their data.

  5. On the mathematical analysis of Ebola hemorrhagic fever: deathly infection disease in West African countries.

    PubMed

    Atangana, Abdon; Goufo, Emile Franc Doungmo

    2014-01-01

    For a given West African country, we constructed a model describing the spread of the deathly disease called Ebola hemorrhagic fever. The model was first constructed using the classical derivative and then converted to the generalized version using the beta-derivative. We studied in detail the endemic equilibrium points and provided the Eigen values associated using the Jacobian method. We furthered our investigation by solving the model numerically using an iteration method. The simulations were done in terms of time and beta. The study showed that, for small portion of infected individuals, the whole country could die out in a very short period of time in case there is not good prevention.

  6. Introduction

    USDA-ARS?s Scientific Manuscript database

    In the summer of 2009 an interdisciplinary group of leading scientists from 11 countries assembled on the shores of Lake Mendota in Madison, Wisconsin for a three-day conference on sustaining soil productivity in response to global climate change. Although there have been numerous conferences on cli...

  7. CHARACTERIZATION AND REMEDIATION TECHNOLOGIES FOR LIGHT NONAQUEOUS PHASE LIQUIDS

    EPA Science Inventory

    Light nonaqueous phase liquids (LNAPLs), principally petroleum products, affect ground-water quality at numerous sites across this country and throughout the world. Petroleum products are typically multi-component organic mixtures composed of chemicals with a wide range of solubi...

  8. Neurobehavioural methods, effects and prevention: workers' human rights are why the field matters for developing countries.

    PubMed

    London, L

    2009-11-01

    Little research into neurobehavioural methods and effects occurs in developing countries, where established neurotoxic chemicals continue to pose significant occupational and environmental burdens, and where agents newly identified as neurotoxic are also widespread. Much of the morbidity and mortality associated with neurotoxic agents remains hidden in developing countries as a result of poor case detection, lack of skilled personnel, facilities and equipment for diagnosis, inadequate information systems, limited resources for research and significant competing causes of ill-health, such as HIV/AIDS and malaria. Placing the problem in a human rights context enables researchers and scientists in developing countries to make a strong case for why the field of neurobehavioural methods and effects matters because there are numerous international human rights commitments that make occupational and environmental health and safety a human rights obligation.

  9. Ability of the Confined Explosive Component Water Gap Test STANAG 4363 to Assess the Shock Sensitivity of MM-Scale Detonators

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lefrancois, A S; Roeske, F; Benterou, J

    2006-02-10

    The Explosive Component Water Gap Test (ECWGT) has been validated to assess the shock sensitivity of lead and booster components having a diameter larger than 5 mm. Several countries have investigated by experiments and numerical simulations the effect of confinement on the go/no go threshold for Pentaerythritol Tetranitrate (PETN) pellets having a height and diameter of 3 mm, confined by a steel annulus of wall thickness 1-3.5 mm. Confinement of the PETN by a steel annulus of the same height of the pellet with 1-mm wall thickness makes the component more sensitive (larger gap). As the wall thickness is increasedmore » to 2-mm, the gap increases a lesser amount, but when the wall thickness is increased to 3.5-mm a decrease in sensitivity is observed (smaller gap). This decrease of the water gap has been reproduced experimentally. Recent numerical simulations using Ignition and Growth model [1] for the PETN Pellet have reproduced the experimental results for the steel confinement up to 2 mm thick [2]. The presence of a stronger re-shock following the first input shock from the water and focusing on the axis have been identified in the pellet due to the steel confinement. The double shock configuration is well-known to lead in some cases to shock desensitization. This work presents the numerical simulations using Ignition and Growth model for LX16 (PETN based HE) and LX19 (CL20 based HE) Pellets [3] in order to assess the shock sensitivity of mm-scale detonators. The pellets are 0.6 mm in diameter and 3 mm length with different type of steel confinement 2.2 mm thick and 4.7 mm thick. The influence of an aluminum confinement is calculated for the standard LX 16 pellet 3 mm in diameter and 3 mm in height. The question of reducing the size of the donor charge is also investigated to small scale the test itself.« less

  10. Smoking and Adverse Maternal and Child Health Outcomes in Brazil

    PubMed Central

    2013-01-01

    Introduction: Numerous studies from high-income countries document the causal relationship between cigarette smoking during pregnancy and adverse maternal and child health (MCH) outcomes. Less research has been conducted in low and middle income countries, but a burgeoning literature can be found for Brazil. Methods: We review Brazilian studies of the prevalence of maternal smoking, the relative risk of smoking-attributable adverse MCH outcomes, and present new estimates for these outcomes, using the attributable fraction method. Results: We found that Brazilian studies of the relative risks of smoking-attributable adverse MCH outcomes were broadly consistent with previous reviews. Based on a comparison of maternal smoking over time, smoking during pregnancy has declined by about 50% over the last 20 years in Brazil. For 2008, we estimate that 5,352 cases of spontaneous abortion, 10,929 cases of preterm birth, 20,717 cases of low birth weight, and 29 cases of sudden infant death syndrome are attributable to maternal smoking. Between 1989 and 2008, the percent of smoking-attributable adverse MCH outcomes in Brazil was at least halved. Conclusions: The results show that over a 20-year period, during which Brazil implemented numerous effective tobacco control measures, the country experienced a dramatic decrease in both maternal smoking prevalence and smoking-attributable adverse MCH outcomes. Countries that implement effective tobacco control measures can expect to reduce both maternal smoking and adverse MCH outcomes, thereby improving the public health. PMID:23873977

  11. Benchmarks for health expenditures, services and outcomes in Africa during the 1990s.

    PubMed Central

    Peters, D. H.; Elmendorf, A. E.; Kandola, K.; Chellaraj, G.

    2000-01-01

    There is limited information on national health expenditures, services, and outcomes in African countries during the 1990s. We intend to make statistical information available for national level comparisons. National level data were collected from numerous international databases, and supplemented by national household surveys and World Bank expenditure reviews. The results were tabulated and analysed in an exploratory fashion to provide benchmarks for groupings of African countries and individual country comparison. There is wide variation in scale and outcome of health care spending between African countries, with poorer countries tending to do worse than wealthier ones. From 1990-96, the median annual per capita government expenditure on health was nearly US$ 6, but averaged US$ 3 in the lowest-income countries, compared to US$ 72 in middle-income countries. Similar trends were found for health services and outcomes. Results from individual countries (particularly Ethiopia, Ghana, Côte d'Ivoire and Gabon) are used to indicate how the data can be used to identify areas of improvement in health system performance. Serious gaps in data, particularly concerning private sector delivery and financing, health service utilization, equity and efficiency measures, hinder more effective health management. Nonetheless, the data are useful for providing benchmarks for performance and for crudely identifying problem areas in health systems for individual countries. PMID:10916913

  12. Socioeconomic inequality in smoking in low-income and middle-income countries: results from the World Health Survey.

    PubMed

    Hosseinpoor, Ahmad Reza; Parker, Lucy Anne; Tursan d'Espaignet, Edouard; Chatterji, Somnath

    2012-01-01

    To assess the magnitude and pattern of socioeconomic inequality in current smoking in low and middle income countries. We used data from the World Health Survey [WHS] in 48 low-income and middle-income countries to estimate the crude prevalence of current smoking according to household wealth quintile. A Poisson regression model with a robust variance was used to generate the Relative Index of Inequality [RII] according to wealth within each of the countries studied. In males, smoking was disproportionately prevalent in the poor in the majority of countries. In numerous countries the poorest men were over 2.5 times more likely to smoke than the richest men. Socioeconomic inequality in women was more varied showing patterns of both pro-rich and pro-poor inequality. In 20 countries pro-rich relative socioeconomic inequality was statistically significant: the poorest women had a higher prevalence of smoking compared to the richest women. Conversely, in 9 countries women in the richest population groups had a statistically significant greater risk of smoking compared to the poorest groups. Both the pattern and magnitude of relative inequality may vary greatly between countries. Prevention measures should address the specific pattern of smoking inequality observed within a population.

  13. Socioeconomic Inequality in Smoking in Low-Income and Middle-Income Countries: Results from the World Health Survey

    PubMed Central

    Hosseinpoor, Ahmad Reza; Parker, Lucy Anne; Tursan d'Espaignet, Edouard; Chatterji, Somnath

    2012-01-01

    Objectives To assess the magnitude and pattern of socioeconomic inequality in current smoking in low and middle income countries. Methods We used data from the World Health Survey [WHS] in 48 low-income and middle-income countries to estimate the crude prevalence of current smoking according to household wealth quintile. A Poisson regression model with a robust variance was used to generate the Relative Index of Inequality [RII] according to wealth within each of the countries studied. Results In males, smoking was disproportionately prevalent in the poor in the majority of countries. In numerous countries the poorest men were over 2.5 times more likely to smoke than the richest men. Socioeconomic inequality in women was more varied showing patterns of both pro-rich and pro-poor inequality. In 20 countries pro-rich relative socioeconomic inequality was statistically significant: the poorest women had a higher prevalence of smoking compared to the richest women. Conversely, in 9 countries women in the richest population groups had a statistically significant greater risk of smoking compared to the poorest groups. Conclusion Both the pattern and magnitude of relative inequality may vary greatly between countries. Prevention measures should address the specific pattern of smoking inequality observed within a population. PMID:22952617

  14. Gender Imbalance and Terrorism in Developing Countries.

    PubMed

    Younas, Javed; Sandler, Todd

    2017-03-01

    This article investigates whether gender imbalance may be conducive to domestic terrorism in developing countries. A female-dominated society may not provide sufficient administration, law, or order to limit domestic terrorism, especially since societies in developing countries primarily turn to males for administration, policing, and paramilitary forces. Other economic considerations support female imbalance resulting in grievance-generated terrorism. Because male dominance may also be linked to terrorism, empirical tests are ultimately needed to support our prediction. Based on panel data for 128 developing countries for 1975 to 2011, we find that female gender imbalance results in more total and domestic terrorist attacks. This female gender imbalance does not affect transnational terrorism in developing countries or domestic and transnational terrorism in developed countries. Further tests show that gender imbalance affects terrorism only when bureaucratic institutions are weak. Many robustness tests support our results.

  15. Gender Imbalance and Terrorism in Developing Countries

    PubMed Central

    Younas, Javed

    2016-01-01

    This article investigates whether gender imbalance may be conducive to domestic terrorism in developing countries. A female-dominated society may not provide sufficient administration, law, or order to limit domestic terrorism, especially since societies in developing countries primarily turn to males for administration, policing, and paramilitary forces. Other economic considerations support female imbalance resulting in grievance-generated terrorism. Because male dominance may also be linked to terrorism, empirical tests are ultimately needed to support our prediction. Based on panel data for 128 developing countries for 1975 to 2011, we find that female gender imbalance results in more total and domestic terrorist attacks. This female gender imbalance does not affect transnational terrorism in developing countries or domestic and transnational terrorism in developed countries. Further tests show that gender imbalance affects terrorism only when bureaucratic institutions are weak. Many robustness tests support our results. PMID:28232755

  16. Can trained lay providers perform HIV testing services? A review of national HIV testing policies.

    PubMed

    Flynn, David E; Johnson, Cheryl; Sands, Anita; Wong, Vincent; Figueroa, Carmen; Baggaley, Rachel

    2017-01-04

    Only an estimated 54% of people living with HIV are aware of their status. Despite progress scaling up HIV testing services (HTS), a testing gap remains. Delivery of HTS by lay providers may help close this testing gap, while also increasing uptake and acceptability of HIV testing among key populations and other priority groups. 50 National HIV testing policies were collated from WHO country intelligence databases, contacts and testing program websites. Data regarding lay provider use for HTS was extracted and collated. Our search had no geographical or language restrictions. This data was then compared with reported data from the Global AIDS Response Progress Reporting (GARPR) from July 2015. Forty-two percent of countries permit lay providers to perform HIV testing and 56% permit lay providers to administer pre-and post-test counseling. Comparative analysis with GARPR found that less than half (46%) of reported data from countries were consistent with their corresponding national HIV testing policy. Given the low uptake of lay provider use globally and their proven use in increasing HIV testing, countries should consider revising policies to support lay provider testing using rapid diagnostic tests.

  17. Estimating the Relationship between Economic Growth and Health Expenditures in ECO Countries Using Panel Cointegration Approach.

    PubMed

    Hatam, Nahid; Tourani, Sogand; Homaie Rad, Enayatollah; Bastani, Peivand

    2016-02-01

    Increasing knowledge of people about health leads to raising the share of health expenditures in government budget continuously; although governors do not like this rise because of budget limitations. This study aimed to find the association between health expenditures and economic growth in ECO countries. We added health capital in Solow model and used the panel cointegration approach to show the importance of health expenditures in economic growth. For estimating the model, first we used Pesaran cross-sectional dependency test, after that we used Pesaran CADF unit root test, and then we used Westerlund panel cointegration test to show if there is a long-term association between variables or not. After that, we used chaw test, Breusch-Pagan test and Hausman test to find the form of the model. Finally, we used OLS estimator for panel data. Findings showed that there is a positive, strong association between health expenditures and economic growth in ECO countries. If governments increase investing in health, the total production of the country will be increased, so health expenditures are considered as an investing good. The effects of health expenditures in developing countries must be higher than those in developed countries. Such studies can help policy makers to make long-term decisions.

  18. Towards standard testbeds for numerical relativity

    NASA Astrophysics Data System (ADS)

    Alcubierre, Miguel; Allen, Gabrielle; Bona, Carles; Fiske, David; Goodale, Tom; Guzmán, F. Siddhartha; Hawke, Ian; Hawley, Scott H.; Husa, Sascha; Koppitz, Michael; Lechner, Christiane; Pollney, Denis; Rideout, David; Salgado, Marcelo; Schnetter, Erik; Seidel, Edward; Shinkai, Hisa-aki; Shoemaker, Deirdre; Szilágyi, Béla; Takahashi, Ryoji; Winicour, Jeff

    2004-01-01

    In recent years, many different numerical evolution schemes for Einstein's equations have been proposed to address stability and accuracy problems that have plagued the numerical relativity community for decades. Some of these approaches have been tested on different spacetimes, and conclusions have been drawn based on these tests. However, differences in results originate from many sources, including not only formulations of the equations, but also gauges, boundary conditions, numerical methods and so on. We propose to build up a suite of standardized testbeds for comparing approaches to the numerical evolution of Einstein's equations that are designed to both probe their strengths and weaknesses and to separate out different effects, and their causes, seen in the results. We discuss general design principles of suitable testbeds, and we present an initial round of simple tests with periodic boundary conditions. This is a pivotal first step towards building a suite of testbeds to serve the numerical relativists and researchers from related fields who wish to assess the capabilities of numerical relativity codes. We present some examples of how these tests can be quite effective in revealing various limitations of different approaches, and illustrating their differences. The tests are presently limited to vacuum spacetimes, can be run on modest computational resources and can be used with many different approaches used in the relativity community.

  19. Multinational Quality Assurance

    ERIC Educational Resources Information Center

    Kinser, Kevin

    2011-01-01

    Multinational colleges and universities pose numerous challenges to the traditional models of quality assurance that are designed to validate domestic higher education. When institutions cross international borders, at least two quality assurance protocols are involved. To guard against fraud and abuse, quality assurance in the host country is…

  20. Cyberbullying: A Cross-Cultural Perspective

    ERIC Educational Resources Information Center

    Baek, Jieun; Bullock, Lyndal M.

    2014-01-01

    Numerous studies conducted in different countries have focused on empirical research and literature reviews on prevalence, consequences, and strategies relative to cyberbullying; however, there is a lack of research regarding cyberbullying from a cross-cultural perspective. This article reviews recent research on cyberbullying and presents…

  1. Los Ninos y el Mundo: Children's Books in Spanish from around the World.

    ERIC Educational Resources Information Center

    Schon, Isabel

    2001-01-01

    Offers brief descriptions of 32 children's books (or book series) in Spanish that introduce children to numerous countries around the world. Notes a web site address listing high-quality books in Spanish for children and adolescents. (SR)

  2. Repairing/strengthening of bridges with post-tensioned FRP materials and performance evaluation.

    DOT National Transportation Integrated Search

    2015-09-01

    One of the challenges that transportation agencies are facing is to keep bridges in good condition during their service life. : Numerous bridges are classified as structurally and/or functionally deficient in the country. In the state of Louisiana, 4...

  3. Numerical modeling and experimental validation of thermoplastic composites induction welding

    NASA Astrophysics Data System (ADS)

    Palmieri, Barbara; Nele, Luigi; Galise, Francesco

    2018-05-01

    In this work, a numerical simulation and experimental test of the induction welding of continuous fibre-reinforced thermoplastic composites (CFRTPCs) was provided. The thermoplastic Polyamide 66 (PA66) with carbon fiber fabric was used. Using a dedicated software (JMag Designer), the influence of the fundamental process parameters such as temperature, current and holding time was investigated. In order to validate the results of the simulations, and therefore the numerical model used, experimental tests were carried out, and the temperature values measured during the tests were compared with the aid of an optical pyrometer, with those provided by the numerical simulation. The mechanical properties of the welded joints were evaluated by single lap shear tests.

  4. Cost-effectiveness of human papillomavirus DNA testing in the United Kingdom, The Netherlands, France, and Italy.

    PubMed

    Kim, Jane J; Wright, Thomas C; Goldie, Sue J

    2005-06-15

    European countries with established cytology-based screening programs for cervical cancer will soon face decisions about whether to incorporate human papillomavirus (HPV) DNA testing and what strategies will be most cost-effective. We assessed the cost-effectiveness of incorporating HPV DNA testing into existing cervical cancer screening programs in the United Kingdom, The Netherlands, France, and Italy. We created a computer-based model of the natural history of cervical carcinogenesis for each using country-specific data on cervical cancer risk and compared each country's current screening policy with two new strategies: 1) cytology throughout a woman's lifetime, using HPV DNA testing as a triage strategy for equivocal cytology results ("HPV triage"), as well as 2) cytology until age 30 years and HPV DNA testing in combination with cytology in women more than 30 years of age ("combination testing"). Outcomes included reduction in lifetime cervical cancer risk, increase in life expectancy, lifetime costs, and incremental cost-effectiveness ratios, expressed as cost per year of life saved. We explored alternative protocols and conducted sensitivity analysis on key parameters of the model over a relevant range of values to identify the most cost-effective options for each country. Both HPV DNA testing strategies, HPV triage and combination testing, were more effective than each country's status quo screening policy. Incremental cost-effectiveness ratios for HPV triage were less than $13,000 per year of life saved, whereas those for combination testing ranged from $9800 to $75,900 per year of life saved, depending on screening interval. We identified options that would be very cost-effective (i.e., cost-effectiveness ratio less than the gross domestic product per capita) in each of the four countries. HPV DNA testing has the potential to improve health benefits at a reasonable cost compared with current screening policies in four European countries.

  5. Impacts of heavy groundwater pumping on hydrogeological conditions in Libya: Past and present development and future prognosis on a regional scale

    NASA Astrophysics Data System (ADS)

    Elgzeli, Yousef M.; Ondovčin, Tomáš; Hrkal, Zbyněk; Krásný, Jiří; Mls, Jiří

    2013-06-01

    Elgzeli, Y.M., Ondovčin, T., Hrkal, Z., Krasny, J. and Mls, J. 2011. Impacts of heavy groundwater pumping on hydrogeological conditions in Libya: Past and present development and future prognosis on a regional scale. Acta Geologica Polonica, 63 (2), 283-296. Warszawa. Libya, like many other regions with arid climates, suffers from inadequate water resources to cover all the needs of this rapidly developing country. Increasing amounts of water are needed to supply the population, as well as for agricultural irrigation and industrial use. As groundwater is the main water source in the country, it represents a natural resource of the highest economic and social importance. Conceptual and numerical models were implemented on a regional scale to show how the natural situation has changed following heavy groundwater abstraction during the last decades in the northwestern part of the country. The results of the numerical model indicated that the current zones of depression of the piezometric surface could have been caused by smaller withdrawn amounts than previously estimated. The differences in the assessed withdrawn groundwater volumes seem to be quite high and might have a considerable influence on the future possibilities of groundwater use in the study region.

  6. The History of the Soil Science Society of Nigeria

    NASA Astrophysics Data System (ADS)

    Okechukwu Chude, Victor

    2013-04-01

    The Soil Science Society of Nigeria (SSSN) founded in 1968, is a registered member of the African Soil Science Association, International Union of Soil Science and the Global Soil Partnership. The Society aims at promoting and fostering better understanding of basic and applied Soil Science in Nigeria. The society also strives to enhance the dissemination of knowledge in all aspects of Soil science and shares ideas with National and International Societies through conferences, symposium, lectures, seminars and journal publications. The numerical strength of the society is 600 members (student, ordinary ,life and corporate). The soil science society of Nigeria has provided invaluable services in the formulation of agricultural land and fertilizer use strategies and policies of the country. The existing reconnaissance soil map of Nigeria typifies one of the major professional services rendered to the country by the society and its members. Despite the numerous contributions the society has made to the advancement of soil science in the country, the larger society is not aware of the its existence. This is largely because of our limited soil extension activities to land users due to lack of funds. If the society can attract donor funds, this will go a long way in enhancing the capacity and capability of the society.

  7. Development of risk reduction behavioral counseling for Ebola virus disease survivors enrolled in the Sierra Leone Ebola Virus Persistence Study, 2015-2016.

    PubMed

    Abad, Neetu; Malik, Tasneem; Ariyarajah, Archchun; Ongpin, Patricia; Hogben, Matthew; McDonald, Suzanna L R; Marrinan, Jaclyn; Massaquoi, Thomas; Thorson, Anna; Ervin, Elizabeth; Bernstein, Kyle; Ross, Christine; Liu, William J; Kroeger, Karen; Durski, Kara N; Broutet, Nathalie; Knust, Barbara; Deen, Gibrilla F

    2017-09-01

    During the 2014-2016 West Africa Ebola Virus Disease (EVD) epidemic, the public health community had concerns that sexual transmission of the Ebola virus (EBOV) from EVD survivors was a risk, due to EBOV persistence in body fluids of EVD survivors, particularly semen. The Sierra Leone Ebola Virus Persistence Study was initiated to investigate this risk by assessing EBOV persistence in numerous body fluids of EVD survivors and providing risk reduction counseling based on test results for semen, vaginal fluid, menstrual blood, urine, rectal fluid, sweat, tears, saliva, and breast milk. This publication describes implementation of the counseling protocol and the key lessons learned. The Ebola Virus Persistence Risk Reduction Behavioral Counseling Protocol was developed from a framework used to prevent transmission of HIV and other sexually transmitted infections. The framework helped to identify barriers to risk reduction and facilitated the development of a personalized risk-reduction plan, particularly around condom use and abstinence. Pre-test and post-test counseling sessions included risk reduction guidance, and post-test counseling was based on the participants' individual test results. The behavioral counseling protocol enabled study staff to translate the study's body fluid test results into individualized information for study participants. The Ebola Virus Persistence Risk Reduction Behavioral Counseling Protocol provided guidance to mitigate the risk of EBOV transmission from EVD survivors. It has since been shared with and adapted by other EVD survivor body fluid testing programs and studies in Ebola-affected countries.

  8. Co-circulation of Crimean-Congo Hemorrhagic Fever virus strains Asia 1 and 2 between the border of Iran and Pakistan.

    PubMed

    Shahhosseini, Nariman; Jafarbekloo, Ahmad; Telmadarraiy, Zakkyeh; Chinikar, Sadegh; Haeri, Ali; Nowotny, Norbert; Groschup, Martin H; Fooks, Anthony R; Faghihi, Faezeh

    2017-11-01

    Crimean-Congo Hemorrhagic Fever (CCHF) is a tick-borne viral disease that is transmitted by numerous species of ticks, which serve both as a reservoir and vector of CCHF virus (CCHFV). Molecular and serological tests were undertaken on hard ticks (Ixodidae spp.) and samples from livestock were collected in 2015 from Chabahar County in Southeast Iran. Using RT-PCR, the ticks were tested for the presence of CCHFV. In addition, seven livestock were serologically tested for the presence of IgG antibodies using an ELISA test. IgG antibodies against CCHFV were detected in one of 7 of the livestock that were tested. In total, 49 ticks including five species: Rhipicephalus sanguineus, Hyalomma anatolicum , Hy. asiaticum, Hy. dromedarii and Hy. marginatum with a prevalence of 46.9%, 32.7%, 4.1%, 4.1% and 2.1% respectively were identified. CCHFV was detected in three ticks among 49 collected ticks. The ticks infected with CCHFV belonged to the genus Hyalomma and Rhipicephalus. Phylogenetic analysis demonstrated that two sequences clustered in clade IV (Asia-1) and one sequence was located within clade IV (Asia-2). Most of the animal and human CCHF cases of the country are reported from Sistan and Baluchistan provinces. Regular monitoring programs in the tick population and livestock are needed in the future.

  9. A review on camel brucellosis: a zoonosis sustained by ignorance and indifference

    PubMed Central

    Sprague, Lisa D; Al-Dahouk, Sascha; Neubauer, Heinrich

    2012-01-01

    In many developing countries of Asia and Africa, camels are one of the most important sources of income for the nomadic population. With increasing urbanization, camel milk and meat have gained a wider market and commercialization and consumption of camel products are on the rise. Camel brucellosis can be encountered in all camel rearing countries with exception of Australia. High animal and herd prevalences have been reported from numerous countries, which not only pose a continuous risk for human infection, but also increase the spread of infection through uncontrolled trade of clinically inconspicuous animals. This short review aims at providing an overview on diagnostic investigations, as well as the public health and economic impact of brucellosis in old world camels. PMID:23265371

  10. Costs, payments, and incentives in family planning programs: a review for developing countries.

    PubMed

    Ross, J A; Isaacs, S L

    1988-01-01

    Anxieties about financing health and family planning programs have grown in recent years, leading to discussions of cost-recovery measures that would raise charges to the consumer. Yet some governments wish to lower cost to encourage contraceptive use, and a few use incentives and disincentives. Data from numerous developing countries are presented on contraceptive cost topics: charges for contraceptive supplies and services, in both public and private sectors, and conversely, payments made to clients and providers to offset costs and to increase contraceptive use. The data show great diversity, and much inconsistency within countries, indicating that the structures of charges, payments, and incentives in many programs could be improved. Ethical considerations are discussed, and guidelines are suggested for developing effective financial policies.

  11. Availability, accessibility, and affordability of neurodiagnostic tests in 37 countries.

    PubMed

    McLane, Hannah C; Berkowitz, Aaron L; Patenaude, Bryan N; McKenzie, Erica D; Wolper, Emma; Wahlster, Sarah; Fink, Günther; Mateen, Farrah J

    2015-11-03

    To determine the availability, accessibility, and affordability of EEG, EMG, CSF analysis, head CT, and brain MRI for neurologic disorders across countries. An online, 60-question survey was distributed to neurology practitioners in 2014 to assess the presence, wait time, and cost of each test in private and public health sectors. Data were stratified by World Bank country income group. Affordability was calculated with reference to the World Health Organization's definition of catastrophic health expenditure as health-related out-of-pocket expenditure of >40% of disposable household income, and assessment of providers' perceptions of affordability to the patient. Availability of EEG and EMG is correlated with higher World Bank income group (correlation coefficient 0.38, test for trend p = 0.046; 0.376, p = 0.043); CSF, CT, and MRI did not show statistically significant associations with income groups. Patients in public systems wait longer for neurodiagnostic tests, especially MRI, EEG, and urgent CT (p < 0.0001). The mean cost per test, across all tests, was lower in the public vs private sector (US $55.25 vs $214.62, p < 0.001). Each drop in World Bank income group is associated with a 29% decrease in the estimated share of the population who can afford a given test (95% confidence interval -33.4, 25.2; p < 0.001). In most low-income countries surveyed, only the top 10% or 20% of the population was able to afford tests below catastrophic levels. In surveyed lower-middle-income countries, >40% of the population, on average, could not afford neurodiagnostic tests. Neurodiagnostic tests are least affordable in the lowest income settings. Closing this "diagnostic gap" for countries with the lowest incomes is essential. © 2015 American Academy of Neurology.

  12. Ethical issues in transnational "mail order" oocyte donation.

    PubMed

    Heng, B C

    2006-12-01

    The rising demand for donor oocytes in developed countries has led to what is referred to as transnational or international oocyte donation, or the outsourcing of oocyte donation to poorer countries. In a further twist, frozen sperm from a recipient's partner can also be mailed to a foreign clinic to fertilize donor oocytes, and the resulting embryos are mailed back, cryopreserved, for transfer to the recipient. Among the numerous ethical concerns raised by this practice of mail order oocyte donation, the most obvious are that underprivileged women from poorer countries are often exploited; fertility physicians from richer counties abdicate responsibility for the welfare of donors; and responsibility could become an issue of contention if transmission of disease to the oocyte recipient or congenital defects in offspring born from such oocyte donation were to occur. Moreover, savings from utilizing donors from poorer countries ought to be shared with oocyte recipients.

  13. Project Delivery Methods and Contracting Approaches Available for Implementation by the Texas Department of Transportation

    DOT National Transportation Integrated Search

    2001-10-01

    Public agencies across the country are pursuing innovative project delivery methods such as design-build (D-B) and construction manager-at-risk (CM-at-risk) to improve cycle-time performance on projects, and numerous transportation departments are cu...

  14. Small Projects First

    ERIC Educational Resources Information Center

    Shang-Kuei, Chen

    1975-01-01

    For thousands of years China has been troubled by droughts and floods. In the past 25 years, the country has worked to alleviate these problems. Numerous water conservation projects requiring the communal efforts of the people have been carried out. Record grain crops have resulted from these projects. (MA)

  15. Language Learning: A Worldwide Perspective

    ERIC Educational Resources Information Center

    Christian, Donna; Pufahl, Ingrid U.; Rhodes, Nancy C.

    2005-01-01

    Numerous reports and articles have decried the mediocrity of U.S. students' foreign language skills and have called for improved language education. One study that looked at foreign language education in 19 countries suggests several characteristics of successful foreign language programs: starting early, providing an articulated framework,…

  16. Repairing/strengthening of bridges with post-tensioned FRP materials and performance evaluation : [tech summary].

    DOT National Transportation Integrated Search

    2015-09-01

    One of the challenges that transportation agencies are facing is keeping bridges in good condition during their : service life. Numerous bridges are classi ed as structurally and/or functionally de cient in the country. In the : state of Louisi...

  17. [Proposal for magnetic/electromagnetic fields protection norms on national level].

    PubMed

    Dordević, Drago; Raković, Dejan

    2008-01-01

    The modern life is not possible without application of magnetic/electromagnetic fields, which can be both helpful and harmful for human body. The non-ionizing radiation, especially magnetic/electromagnetic fields of all frequencies (0-300 GHz), can have many harmful effects on the human health that is confirmed by numerous epidemiological studies, studies with volunteers, animal studies, and in vitro studies. Proposal for magnetic/electromagnetic fields protection norms on national level based on the WHO Program for Environment, International Commission on Non-Ionizing Radiation Protection (ICNIRP)], and WHO International EMF Project. Protection from harmful effects of the magnetic/electromagnetic fields is still a great problem in many countries of modern society--huge costs, impaired quality of life, and more important, damage to the human health. Numerous data and publications of harmful effects of the magnetic/electromagnetic fields represents one's country basic necessary documentation for making decisions and law documents for protection norms on national level concerning the health maintenance according to the ICNIRP normatives.

  18. Contract-based electricity markets in developing countries: Overcoming inefficiency constraints

    NASA Astrophysics Data System (ADS)

    Perera, M. N. Susantha

    The electric utility sector throughout the world has been undergoing significant changes. It is changing from its traditional, central-station generation model managed under a vertically integrated monopoly to a more market-dependent business. In the rich industrialized countries, this change has progressed rapidly with the emergence of competitive markets---not only in the area of electricity generation, but also in the extension of such markets down to the level of retail domestic consumer. Developing countries, on the other hand, are trying to attract much-needed investment capital for their power sector expansion activities, particularly for the expansion of generating capacity, through the involvement of the private sector. Unlike their industrialized counterparts, they are facing many limitations in transforming the mostly government-owned monopolies into market-driven businesses, thereby creating an environment that is conducive to private sector participation. Amongst these limitations are the lack of a well-developed, local private sector or domestic financial market that can handle the sophisticated power sector financing; inadequate legal and regulatory frameworks that can address the many complexities of private power development; and numerous risk factors including political risks. This dissertation research addresses an important inefficiency faced by developing countries in the new contract-based market structure that has emerged within these countries. It examines the inefficiencies brought on by restrictions in the contracts, specifically those arising from the guaranteed purchase conditions that are typically included in contracts between the purchasing utility and independent power producers in this new market. The research attempts to provide a solution for this problem and proposes a methodology that enables the parties to conduct their businesses in a cost-efficient manner within a cooperative environment. The situation described above is modeled as a cooperative game based on the relationships that typically exist in power pools. This model draws its mathematical basis from game theory. This research demonstrates that the proposed model has a theoretical solution that yields an efficient allocation of resources. Furthermore, this solution has a significant practical validity as a tool that can be employed by developing country governments faced with similar market situations. In the case study presented here, the model is tested using data from a small developing country.

  19. How might acupuncture work? A systematic review of physiologic rationales from clinical trials.

    PubMed

    Moffet, Howard H

    2006-07-07

    Scientific interest in acupuncture has led numerous investigators to conduct clinical trials to test the efficacy of acupuncture for various conditions, but the mechanisms underlying acupuncture are poorly understood. The author conducted a PubMed search to obtain a fair sample of acupuncture clinical trials published in English in 2005. Each article was reviewed for a physiologic rationale, as well as study objectives and outcomes, experimental and control interventions, country of origin, funding sources and journal type. Seventy-nine acupuncture clinical trials were identified. Twenty-six studies (33%) offered no physiologic rationale. Fifty-three studies (67%) posited a physiologic basis for acupuncture: 33 (62% of 53) proposed neurochemical mechanisms, 2 (4%) segmental nervous system effects, 6 (11%) autonomic nervous system regulation, 3 (6%) local effects, 5 (9%) effects on brain function and 5 (9%) other effects. No rationale was proposed for stroke; otherwise having a rationale was not associated with objective, positive or negative findings, means of intervention, country of origin, funding source or journal type. The dominant explanation for how acupuncture might work involves neurochemical responses and is not reported to be dependent on treatment objective, specific points, means or method of stimulation. Many acupuncture trials fail to offer a meaningful rationale, but proposing a rationale can help investigators to develop and test a causal hypothesis, choose an appropriate control and rule out placebo effects. Acupuncture may stimulate self-regulatory processes independent of the treatment objective, points, means or methods used; this would account for acupuncture's reported benefits in so many disparate pathologic conditions.

  20. Fertility, income distribution, and economic growth: theory and cross-country evidence.

    PubMed

    Galor, O; Zang, H

    1997-05-01

    The authors perform discriminatory, empirical tests of a theoretical model that predicts that family size adversely affects output per capita and nonsteady state growth rates. Neoclassical models posit that adverse output and nonsteady growth rates are affected by labor force growth (LFG) or population growth (PG). This study tests whether family size (FS) will be more significant than LFG or PG in explaining differences in economic growth (EG) rates across countries during 1960-88. A proxy variable for the public education system was used to separate government interventions on human capital formation from market forces. Data were obtained for 73 countries, which exclude centrally planned economies, oil-producing countries, and those with less than 1 million population. The empirical test is run with 58-country, 45-country, and 96-country samples to test for robustness and reliability. The empirical test supports the theoretical model. It demonstrates that equal distribution of income and smaller FS enhance EG. With income inequality, the effect of FS was significant, and the effect of the LFG rate or PG rate was insignificant. With a given FS, LFG was positively correlated with EG. A reduction of the net fertility rate by one point would increase the worker output growth rate by 0.25%, and the differences in growth rates between high- and low-fertility countries would be 1%. An increase in the income share of the bottom 60% would increase the growth rate of worker output by about 1%. Higher investments in public or private education would be conducive to growth.

  1. Analysis of endocrine activity in drinking water, surface water and treated wastewater from six countries.

    PubMed

    Leusch, Frederic D L; Neale, Peta A; Arnal, Charlotte; Aneck-Hahn, Natalie H; Balaguer, Patrick; Bruchet, Auguste; Escher, Beate I; Esperanza, Mar; Grimaldi, Marina; Leroy, Gaela; Scheurer, Marco; Schlichting, Rita; Schriks, Merijn; Hebert, Armelle

    2018-08-01

    The aquatic environment can contain numerous micropollutants and there are concerns about endocrine activity in environmental waters and the potential impacts on human and ecosystem health. In this study a complementary chemical analysis and in vitro bioassay approach was applied to evaluate endocrine activity in treated wastewater, surface water and drinking water samples from six countries (Germany, Australia, France, South Africa, the Netherlands and Spain). The bioassay test battery included assays indicative of seven endocrine pathways, while 58 different chemicals, including pesticides, pharmaceuticals and industrial compounds, were analysed by targeted chemical analysis. Endocrine activity was below the limit of quantification for most water samples, with only two of six treated wastewater samples and two of six surface water samples exhibiting estrogenic, glucocorticoid, progestagenic and/or anti-mineralocorticoid activity above the limit of quantification. Based on available effect-based trigger values (EBT) for estrogenic and glucocorticoid activity, some of the wastewater and surface water samples were found to exceed the EBT, suggesting these environmental waters may pose a potential risk to ecosystem health. In contrast, the lack of bioassay activity and low detected chemical concentrations in the drinking water samples do not suggest a risk to human endocrine health, with all samples below the relevant EBTs. Copyright © 2018 Elsevier Ltd. All rights reserved.

  2. Capturing the Flatness of a peer-to-peer lending network through random and selected perturbations

    NASA Astrophysics Data System (ADS)

    Karampourniotis, Panagiotis D.; Singh, Pramesh; Uparna, Jayaram; Horvat, Emoke-Agnes; Szymanski, Boleslaw K.; Korniss, Gyorgy; Bakdash, Jonathan Z.; Uzzi, Brian

    Null models are established tools that have been used in network analysis to uncover various structural patterns. They quantify the deviance of an observed network measure to that given by the null model. We construct a null model for weighted, directed networks to identify biased links (carrying significantly different weights than expected according to the null model) and thus quantify the flatness of the system. Using this model, we study the flatness of Kiva, a large international crownfinancing network of borrowers and lenders, aggregated to the country level. The dataset spans the years from 2006 to 2013. Our longitudinal analysis shows that flatness of the system is reducing over time, meaning the proportion of biased inter-country links is growing. We extend our analysis by testing the robustness of the flatness of the network in perturbations on the links' weights or the nodes themselves. Examples of such perturbations are event shocks (e.g. erecting walls) or regulatory shocks (e.g. Brexit). We find that flatness is unaffected by random shocks, but changes after shocks target links with a large weight or bias. The methods we use to capture the flatness are based on analytics, simulations, and numerical computations using Shannon's maximum entropy. Supported by ARL NS-CTA.

  3. Performance test of a low cost roof-mounted wind turbine

    NASA Astrophysics Data System (ADS)

    Figueroa-Espinoza, Bernardo; Quintal, Roberto; Gou, Clément; Aguilar, Alicia

    2013-11-01

    A low cost wind turbine was implemented based on the ideas put forward by Hugh Piggot in his book ``A wind turbine recipe book,'' where such device is developed using materials and manufacturing processes available (as much as possible) in developing countries or isolated communities. The wind turbine is to be mounted on a two stories building roof in a coastal zone of Mexico. The velocity profiles and turbulence intensities for typical wind conditions on top of the building roof were analyzed using numerical simulations (RANS) in order to locate the turbine hub above any recirculation and near the maximum average speed. The coefficient of performance is going to be evaluated experimentally by measuring the electrical power generation and wind characteristics that drive the wind turbine on the field. These experimental results will be applied on the improvement of the wind turbine design, as well as the validation of a numerical simulation model that couples the wind characteristics obtained through CFD with the Blade Element Method (BEM) and an electro-mechanical model of the turbine-shaft-generator ensemble. Special thanks to the Coordinación de Investigación Científica of the Universidad Michoacana de San Nicolás de Hidalgo for their support.

  4. Operational Forecasting and Warning systems for Coastal hazards in Korea

    NASA Astrophysics Data System (ADS)

    Park, Kwang-Soon; Kwon, Jae-Il; Kim, Jin-Ah; Heo, Ki-Young; Jun, Kicheon

    2017-04-01

    Coastal hazards caused by both Mother Nature and humans cost tremendous social, economic and environmental damages. To mitigate these damages many countries have been running the operational forecasting or warning systems. Since 2009 Korea Operational Oceanographic System (KOOS) has been developed by the leading of Korea Institute of Ocean Science and Technology (KIOST) in Korea and KOOS has been operated in 2012. KOOS is consists of several operational modules of numerical models and real-time observations and produces the basic forecasting variables such as winds, tides, waves, currents, temperature and salinity and so on. In practical application systems include storm surges, oil spills, and search and rescue prediction models. In particular, abnormal high waves (swell-like high-height waves) have occurred in the East coast of Korea peninsula during winter season owing to the local meteorological condition over the East Sea, causing property damages and the loss of human lives. In order to improve wave forecast accuracy even very local wave characteristics, numerical wave modeling system using SWAN is established with data assimilation module using 4D-EnKF and sensitivity test has been conducted. During the typhoon period for the prediction of sever waves and the decision making support system for evacuation of the ships, a high-resolution wave forecasting system has been established and calibrated.

  5. Optimization of Diode Laser System to Treat Benign Prostate Hyperplasia Final Report CRADA No. TSB-1154-95

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    London, Richard A; Byrne, Mark

    Benign prostate hyperplasia (BPH) is a pervasive condition of enlargement of the male prostate gland which leads to several urinary difficulties ranging from hesitancy to incontinence to kidney dysfunction in severe cases. Currently the most common therapy is transurethral resection of the prostate (TURP) utilizing an electrosurgical device. Although TURP is largely successful, new BPH therapy methods are desired to reduce the cost and recovery time, improve the success rate, and reduce side effects. Recently, lasers have been introduced for this purpose. Indigo Medical Inc. is currently engaged in the development, testing, and preparation for sales of a new diodemore » laser based BPH therapy system. The development is based on laboratory experiments, animal studies, and a limited FDA-approved clinical trial in the US and in other countries. The addition of sophisticated numerical modeling, of the sort that has been highly developed at Lawrence Livermore National Laboratory, can greatly aid in the design of the system and treatment protocol. The benefits to DOE include the maintenance and advancement of numerical modeling expertise in radiation-matter interactions of the sort essential for the stockpile stewardship, inertial confinement fusion, and advanced manufacturing, and the push on advanced scientific computational methods, ultimately in areas such as 3-D transport.« less

  6. Should all suspected tuberculosis cases in high income countries be tested with GeneXpert?

    PubMed

    Vella, Venanzio; Broda, Agnieszka; Drobniewski, Francis

    2018-05-01

    In countries with a low incidence of multidrug-resistant tuberculosis (MDR-TB), universal testing with GeneXpert might not be always cost-effective. This study provides hospital managers in low MDR-TB incidence countries with criteria on when decentralised universal GeneXpert testing would make sense. The alternatives taken into consideration include: universal microbiological culture and drug susceptibility testing (DST) only (comparator); as above but with concurrent centralized GeneXpert in a referral laboratory vs a decentralized GeneXpert system in every hospital to test smear-positive cases only; as above but testing all samples with GeneXpert regardless of smear status. The parameters were from the national TB statistics for England and from a systematic review. Decentralised GeneXpert to test any suspected TB case was the most cost-effective option when 6% or more TB patients belonged to the high-risk group, defined as previous TB diagnosis and or being born in countries with a high MDR-TB incidence. Hospital managers in England and other low MDR-TB incidence countries could use these findings to decide when to invest in GeneXpert or other molecular diagnostics with similar performance criteria for TB diagnostics. Copyright © 2017 Elsevier Ltd. All rights reserved.

  7. Appropriateness of the TOEIC[R] Bridge Test for Students in Three Countries of South America

    ERIC Educational Resources Information Center

    Sinharay, Sandip; Powers, Donald E.; Feng, Ying; Saldivia, Luis; Giunta, Anthony; Simpson, Annabelle; Weng, Vincent

    2009-01-01

    In order to facilitate the interpretation of test scores from the TOEIC[R] "Bridge" as a measure of English language proficiency, one form of the test was administered to more than 6000 test takers in three South American countries--Colombia, Chile and Ecuador. The appropriateness of the TOEIC "Bridge" test as a measure of…

  8. White-tailed deer in the southern forest habitat

    Treesearch

    Lowell K. Halls

    1969-01-01

    White-tailed deer were once nearly exterminated in the South. In the past several decades, however, improvements in game management and changes in land use patterns have enabled populations to recover. The deer today are more numerous than at any time since white men settled the country

  9. Maritime Domain Awareness In The South China Sea: An Operational Picture Design

    DTIC Science & Technology

    China Sea (SCS) region. Socio- economic issues plague the SCS, including overfishing, piracy, and energy usage, and have forced many countries to...disregard borders, laws, and economic exclusionary zones (EEZ). These actions have caused numerous vessels of interest (VOIs) to turn off required

  10. Tendencies of International Career of Romanian Researchers: Brain Drain?

    ERIC Educational Resources Information Center

    Popescu, Dan; Patrasca, Mihaela; Chivu, Iulia

    2006-01-01

    Recent economic and technological developments have led to a growing international demand for highly skilled human resources. The increased competition for human capital has determined numerous OECD countries to take special measures for attracting and retaining human capital in such fields as: information technology, biotechnology,…

  11. Orange sweet potatoes are an excellent source of vitamin A

    USDA-ARS?s Scientific Manuscript database

    Vitamin A is an essential nutrient required for proper growth and development, vision, red blood cell production, and immune function. An estimated 208 million women and children suffer from vitamin A deficiency worldwide, making vitamin A deficiency a public health problem in numerous countries. Se...

  12. Human exposure assessment resources on the World Wide Web.

    PubMed

    Schwela, Dieter; Hakkinen, Pertti J

    2004-05-20

    Human exposure assessment is frequently noted as a weak link and bottleneck in the risk assessment process. Fortunately, the World Wide Web and Internet are providing access to numerous valuable sources of human exposure assessment-related information, along with opportunities for information exchange. Internet mailing lists are available as potential online help for exposure assessment questions, e.g. RISKANAL has several hundred members from numerous countries. Various Web sites provide opportunities for training, e.g. Web sites offering general human exposure assessment training include two from the US Environmental Protection Agency (EPA) and four from the US National Library of Medicine. Numerous other Web sites offer access to a wide range of exposure assessment information. For example, the (US) Alliance for Chemical Awareness Web site addresses direct and indirect human exposures, occupational exposures and ecological exposure assessments. The US EPA's Exposure Factors Program Web site provides a focal point for current information and data on exposure factors relevant to the United States. In addition, the International Society of Exposure Analysis Web site provides information about how this society seeks to foster and advance the science of exposure analysis. A major opportunity exists for risk assessors and others to broaden the level of exposure assessment information available via Web sites. Broadening the Web's exposure information could include human exposure factors-related information about country- or region-specific ranges in body weights, drinking water consumption, etc. along with residential factors-related information on air changeovers per hour in various types of residences. Further, country- or region-specific ranges on how various tasks are performed by various types of consumers could be collected and provided. Noteworthy are that efforts are underway in Europe to develop a multi-country collection of exposure factors and the European Commission is in the early stages of planning and developing a Web-accessible information system (EIS-ChemRisks) to serve as a single gateway to all major European initiatives on human exposure to chemicals contained and released from cleaning products, textiles, toys, etc.

  13. Hospital choice factors: a case study in Turkey.

    PubMed

    Akinci, Fevzi; Esatoğlu, A Ezel; Tengilimoglu, Dilaver; Parsons, Amy

    2004-01-01

    In an attempt to test the robustness of the numerous American findings related to hospital choice in the context of another country, this study examines the factors affecting hospital choice decisions of 869 patients in three public and one private hospital policlinics in Ankara, Turkey and attempts to determine their importance levels. Identification of these factors and determining their effect levels is important in concentrating management efforts on these key areas and in formulating effective marketing strategies to retain and expand hospital patient bases in the future. Our findings highlight the importance of accessibility of hospital services to consumers in hospital choice as well as the role of hospital's image, its physical appearance, and technological capabilities in informing such choices. American health care managers can use these findings to further understand how patients make choices related to health care facilities and to develop marketing strategies that may more effectively market their facilities.

  14. Food waste prevention in Athens, Greece: The effect of family characteristics.

    PubMed

    Abeliotis, Konstadinos; Lasaridi, Katia; Chroni, Christina

    2016-12-01

    Food waste is a stream that becomes increasingly important in terms of its prevention potential. There is a large number of behaviours that can be associated with food waste generation and the efforts towards food waste prevention. A questionnaire study was carried in order to study consumer behaviour related to food provision and wastage in Greece. Proper practices of the respondents that can prevent the generation of food waste were investigated using nine behavioural scales, which were defined on the basis of similar studies in other countries. A structured questionnaire was utilised in order to test those behaviours against the socio-demographic characteristics of respondents. The results of the study indicate that in terms of inferential statistical analysis, among the numerous variables examined, those that enhance food waste prevention are the involvement of the respondent in cooking, the annoyance towards food waste generation and the education level. © The Author(s) 2016.

  15. Antiviral Perspectives for Chikungunya Virus

    PubMed Central

    Cherian, Sarah

    2014-01-01

    Chikungunya virus (CHIKV) is a mosquito-borne pathogen that has a major health impact in humans and causes acute febrile illness in humans accompanied by joint pains and, in many cases, persistent arthralgia lasting for weeks to years. CHIKV reemerged in 2005-2006 in several parts of the Indian Ocean islands and India after a gap of 32 years, causing millions of cases. The re-emergence of CHIKV has also resulted in numerous outbreaks in several countries in the eastern hemisphere, with a threat to further expand in the near future. However, there is no vaccine against CHIKV infection licensed for human use, and therapy for CHIKV infection is still mainly limited to supportive care as antiviral agents are yet in different stages of testing or development. In this review we explore the different perspectives for chikungunya treatment and the effectiveness of these treatment regimens and discuss the scope for future directions. PMID:24955364

  16. Item analysis of three Spanish naming tests: a cross-cultural investigation.

    PubMed

    Marquez de la Plata, Carlos; Arango-Lasprilla, Juan Carlos; Alegret, Montse; Moreno, Alexander; Tárraga, Luis; Lara, Mar; Hewlitt, Margaret; Hynan, Linda; Cullum, C Munro

    2009-01-01

    Neuropsychological evaluations conducted in the United States and abroad commonly include the use of tests translated from English to Spanish. The use of translated naming tests for evaluating predominately Spanish-speakers has recently been challenged on the grounds that translating test items may compromise a test's construct validity. The Texas Spanish Naming Test (TNT) has been developed in Spanish specifically for use with Spanish-speakers; however, it is unlikely patients from diverse Spanish-speaking geographical regions will perform uniformly on a naming test. The present study evaluated and compared the internal consistency and patterns of item-difficulty and -discrimination for the TNT and two commonly used translated naming tests in three countries (i.e., United States, Colombia, Spain). Two hundred fifty two subjects (136 demented, 116 nondemented) across three countries were administered the TNT, Modified Boston Naming Test-Spanish, and the naming subtest from the CERAD. The TNT demonstrated superior internal consistency to its counterparts, a superior item difficulty pattern than the CERAD naming test, and a superior item discrimination pattern than the MBNT-S across countries. Overall, all three Spanish naming tests differentiated nondemented and moderately demented individuals, but the results suggest the items of the TNT are most appropriate to use with Spanish-speakers. Preliminary normative data for the three tests examined in each country are provided.

  17. 26th International Symposium on Ballistics

    DTIC Science & Technology

    2011-09-16

    judicious use of analytical predictions correlated with ballistic testing and post - test failure morphology investigations. •Our approach...ballistic predictions. The numerical predictions correlate well with the damage pattern. Post - Test Morphology Simulation Imbedded Steel Plate Removed Post ... Test •Numerical simulation of damage to embedded steel plate compares well with the post - test plate morphology •Multi-strike modeling in work

  18. Clean birth kits to improve birth practices: development and testing of a country level decision support tool.

    PubMed

    Hundley, Vanora A; Avan, Bilal I; Ahmed, Haris; Graham, Wendy J

    2012-12-19

    Clean birth practices can prevent sepsis, one of the leading causes of both maternal and newborn mortality. Evidence suggests that clean birth kits (CBKs), as part of package that includes education, are associated with a reduction in newborn mortality, omphalitis, and puerperal sepsis. However, questions remain about how best to approach the introduction of CBKs in country. We set out to develop a practical decision support tool for programme managers of public health systems who are considering the potential role of CBKs in their strategy for care at birth. Development and testing of the decision support tool was a three-stage process involving an international expert group and country level testing. Stage 1, the development of the tool was undertaken by the Birth Kit Working Group and involved a review of the evidence, a consensus meeting, drafting of the proposed tool and expert review. In Stage 2 the tool was tested with users through interviews (9) and a focus group, with federal and provincial level decision makers in Pakistan. In Stage 3 the findings from the country level testing were reviewed by the expert group. The decision support tool comprised three separate algorithms to guide the policy maker or programme manager through the specific steps required in making the country level decision about whether to use CBKs. The algorithms were supported by a series of questions (that could be administered by interview, focus group or questionnaire) to help the decision maker identify the information needed. The country level testing revealed that the decision support tool was easy to follow and helpful in making decisions about the potential role of CBKs. Minor modifications were made and the final algorithms are presented. Testing of the tool with users in Pakistan suggests that the tool facilitates discussion and aids decision making. However, testing in other countries is needed to determine whether these results can be replicated and to identify how the tool can be adapted to meet country specific needs.

  19. Spike-Nosed Bodies and Forward Injected Jets in Supersonic Flow

    NASA Technical Reports Server (NTRS)

    Gilinsky, M.; Washington, C.; Blankson, I. M.; Shvets, A. I.

    2002-01-01

    The paper contains new numerical simulation and experimental test results of blunt body drag reduction using thin spikes mounted in front of a body and one- or two-phase jets injected against a supersonic flow. Numerical simulations utilizing the NASA CFL3D code were conducted at the Hampton University Fluid Mechanics and Acoustics Laboratory (FM&AL) and experimental tests were conducted using the facilities of the IM/MSU Aeromechanics and Gas Dynamics Laboratory. Previous results were presented at the 37th AIAA/ASME/SAE/ASEE Joint Propulsion Conference. Those results were based on some experimental and numerical simulation tests for supersonic flow around spike-nosed or shell-nosed bodies, and numerical simulations were conducted only for a single spike-nosed or shell-nosed body at zero attack angle, alpha=0. In this paper, experimental test results of gas, liquid and solid particle jet injection against a supersonic flow are presented. In addition, numerical simulation results for supersonic flow around a multiple spike-nosed body with non-zero attack angles and with a gas and solid particle forward jet injection are included. Aerodynamic coefficients: drag, C(sub D), lift, C(sub L), and longitudinal momentum, M(sub z), obtained by numerical simulation and experimental tests are compared and show good agreement.

  20. Spike-Nosed Bodies and Forward Injected Jets in Supersonic Flow

    NASA Technical Reports Server (NTRS)

    Gilinsky, M.; Washington, C.; Blankson, I. M.; Shvets, A. I.

    2002-01-01

    The paper contains new numerical simulation and experimental test results of blunt body drag reduction using thin spikes mounted in front of a body and one- or two-phase jets injected against a supersonic flow. Numerical simulations utilizing the NASA CFL3D code were conducted at the Hampton University Fluid Mechanics and Acoustics Laboratory (FM&AL) and experimental tests were conducted using the facilities of the IM/MSU Aeromechanics and Gas Dynamics Laboratory. Previous results were presented at the 37th AIAA/ASME/SAE/ASEE Joint Propulsion Conference. Those results were based on some experimental and numerical simulation tests for supersonic flow around spike-nosed or shell-nosed bodies, and numerical simulations were conducted only for a single spike-nosed or shell-nosed body at zero attack angle, alpha = 0 degrees. In this paper, experimental test results of gas, liquid and solid particle jet injection against a supersonic flow are presented. In addition, numerical simulation results for supersonic flow around a multiple spike-nosed body with non-zero attack angles and with a gas and solid particle forward jet injection are included. Aerodynamic coefficients: drag, C (sub D), lift, C(sub L), and longitudinal momentum, M(sub z), obtained by numerical simulation and experimental tests are compared and show good agreement.

  1. Spatial and Numerical Abilities without a Complete Natural Language

    ERIC Educational Resources Information Center

    Hyde, Daniel C.; Winkler-Rhoades, Nathan; Lee, Sang-Ah; Izard, Veronique; Shapiro, Kevin A.; Spelke, Elizabeth S.

    2011-01-01

    We studied the cognitive abilities of a 13-year-old deaf child, deprived of most linguistic input from late infancy, in a battery of tests designed to reveal the nature of numerical and geometrical abilities in the absence of a full linguistic system. Tests revealed widespread proficiency in basic symbolic and non-symbolic numerical computations…

  2. 76 FR 29991 - Live Goats and Swine for Export; Removal of Certain Testing Requirements

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-24

    ... testing of goats and breeding swine intended for export to countries that do not require such tests. This action will facilitate the exportation of goats and breeding swine by eliminating the need to conduct pre... prior to export. Some countries do not require that goats and breeding swine be tested for tuberculosis...

  3. Testing for purchasing power parity in 21 African countries using several unit root tests

    NASA Astrophysics Data System (ADS)

    Choji, Niri Martha; Sek, Siok Kun

    2017-04-01

    Purchasing power parity is used as a basis for international income and expenditure comparison through the exchange rate theory. However, empirical studies show disagreement on the validity of PPP. In this paper, we conduct the testing on the validity of PPP using panel data approach. We apply seven different panel unit root tests to test the validity of the purchasing power parity (PPP) hypothesis based on the quarterly data on real effective exchange rate for 21 African countries from the period 1971: Q1-2012: Q4. All the results of the seven tests rejected the hypothesis of stationarity meaning that absolute PPP does not hold in those African Countries. This result confirmed the claim from previous studies that standard panel unit tests fail to support the PPP hypothesis.

  4. Test selection, adaptation, and evaluation: a systematic approach to assess nutritional influences on child development in developing countries.

    PubMed

    Prado, Elizabeth L; Hartini, Sri; Rahmawati, Atik; Ismayani, Elfa; Hidayati, Astri; Hikmah, Nurul; Muadz, Husni; Apriatni, Mandri S; Ullman, Michael T; Shankar, Anuraj H; Alcock, Katherine J

    2010-03-01

    Evaluating the impact of nutrition interventions on developmental outcomes in developing countries can be challenging since most assessment tests have been produced in and for developed country settings. Such tests may not be valid measures of children's abilities when used in a new context. We present several principles for the selection, adaptation, and evaluation of tests assessing the developmental outcomes of nutrition interventions in developing countries where standard assessment tests do not exist. We then report the application of these principles for a nutrition trial on the Indonesian island of Lombok. Three hundred children age 22-55 months in Lombok participated in a series of pilot tests for the purpose of test adaptation and evaluation. Four hundred and eighty-seven 42-month-old children in Lombok were tested on the finalized test battery. The developmental assessment tests were adapted to the local context and evaluated for a number of psychometric properties, including convergent and discriminant validity, which were measured based on multiple regression models with maternal education, depression, and age predicting each test score. The adapted tests demonstrated satisfactory psychometric properties and the expected pattern of relationships with the three maternal variables. Maternal education significantly predicted all scores but one, maternal depression predicted socio-emotional competence, socio-emotional problems, and vocabulary, while maternal age predicted socio-emotional competence only. Following the methodological principles we present resulted in tests that were appropriate for children in Lombok and informative for evaluating the developmental outcomes of nutritional supplementation in the research context. Following this approach in future studies will help to determine which interventions most effectively improve child development in developing countries.

  5. Modelling Sawing of Metal Tubes Through FEM Simulation

    NASA Astrophysics Data System (ADS)

    Bort, C. M. Giorgio; Bosetti, P.; Bruschi, S.

    2011-05-01

    The paper presents the development of a numerical model of the sawing process of AISI 304 thin tubes, which is cut through a circular blade with alternating roughing and finishing teeth. The numerical simulation environment is the three-dimensional FEM software Deform™ v.10.1. The teeth actual trajectories were determined by a blade kinematics analysis developed in Matlab™. Due to the manufacturing rolling steps and subsequent welding stage, the tube material is characterized by a gradient of properties along its thickness. Consequently, a simplified cutting test was set up and carried out in order to identify the values of relevant material parameters to be used in the numerical model. The dedicated test was the Orthogonal Tube Cutting test (OTC), which was performed on an instrumented lathe. The proposed numerical model was validated by comparing numerical results and experimental data obtained from sawing tests carried out on an industrial machine. The following outputs were compared: the cutting force, the chip thickness, and the chip contact area.

  6. Numerical simulations in the development of propellant management devices

    NASA Astrophysics Data System (ADS)

    Gaulke, Diana; Winkelmann, Yvonne; Dreyer, Michael

    Propellant management devices (PMDs) are used for positioning the propellant at the propel-lant port. It is important to provide propellant without gas bubbles. Gas bubbles can inflict cavitation and may lead to system failures in the worst case. Therefore, the reliable operation of such devices must be guaranteed. Testing these complex systems is a very intricate process. Furthermore, in most cases only tests with downscaled geometries are possible. Numerical sim-ulations are used here as an aid to optimize the tests and to predict certain results. Based on these simulations, parameters can be determined in advance and parts of the equipment can be adjusted in order to minimize the number of experiments. In return, the simulations are validated regarding the test results. Furthermore, if the accuracy of the numerical prediction is verified, then numerical simulations can be used for validating the scaling of the experiments. This presentation demonstrates some selected numerical simulations for the development of PMDs at ZARM.

  7. Education Takes Hit in Budgets

    ERIC Educational Resources Information Center

    Cavanagh, Sean

    2011-01-01

    After months of arduous negotiation and partisan squabbling, states across the country have produced budgets for the new fiscal year that in many cases will bring deep cuts to state spending, including money for schools. The budget blueprints adopted by numerous states were postscripts to divisive legislative sessions that saw newly elected…

  8. Governing Emotionally Vulnerable Subjects and "Therapisation" of Social Justice

    ERIC Educational Resources Information Center

    Ecclestone, Kathryn; Brunila, Kristiina

    2015-01-01

    In numerous countries, pessimism about enduring social and educational inequalities has produced a discernible therapeutic turn in education policy and practice, and a parallel rise in therapeutic understandings of social justice. Focusing on developments in England and Finland, this article explores the ways in which radical/critical…

  9. Contingent and Marginalised? Academic Development and Part-Time Teachers

    ERIC Educational Resources Information Center

    Anderson, Valerie

    2007-01-01

    Academics employed on non-standard contracts are a numerically significant part of the labour market in higher education. Concerns about access to formal academic development for this staff group have been articulated in many countries in the context of increasing emphasis on teaching quality assessment and employment regulation of…

  10. A Paradigm for EST Materials Preparation.

    ERIC Educational Resources Information Center

    Carreon, Edwina S.; Balarbar, Corazon V.

    In many countries, suitable English for special purposes (ESP) textbooks and materials are difficult to find. ESP teachers and program coordinators often must develop their own materials, but preparing such materials requires training. One model that has served as a guide to numerous ESP materials projects is the Hutchinson and Waters' model. This…

  11. Teaching Geography through "Chinatowns": Global Connections and Local Spaces

    ERIC Educational Resources Information Center

    Ho, Li-Ching; Seow, Tricia

    2013-01-01

    Chinatowns are familiar emblems of "Chineseness" in many countries and are among the most visible and tangible spatial manifestations of Chinese migration. Large and well-established Chinatowns can be found in diverse locales, including New York, San Francisco, Vancouver, Paris, Sydney, and Singapore. Despite sharing numerous easily…

  12. The Information Technology Model Curriculum

    ERIC Educational Resources Information Center

    Ekstrom, Joseph J.; Gorka, Sandra; Kamali, Reza; Lawson, Eydie; Lunt, Barry; Miller, Jacob; Reichgelt, Han

    2006-01-01

    The last twenty years has seen the development of demand for a new type of computing professional, which has resulted in the emergence of the academic discipline of Information Technology (IT). Numerous colleges and universities across the country and abroad have responded by developing programs without the advantage of an existing model for…

  13. An Essay in Culture, Society, Education and Vocational Training

    ERIC Educational Resources Information Center

    Cully, John H.

    2007-01-01

    In many developing countries it is apparent that there are multifarious impediments associated with, and acting upon, educational development and the complexity of diverse socio-cultural landscapes. Indeed, numerous perspectives tend to be overlooked or possibly not even taken under consideration when it comes to the transmission of salient…

  14. Technology, Teachers, and Training: Combining Theory with Macedonia's Experience

    ERIC Educational Resources Information Center

    Hosman, Laura; Cvetanoska, Maja

    2013-01-01

    Numerous developing countries are currently planning or executing projects that introduce technology into their educational systems. This article asserts that such projects will have limited long-term success or impact until they are reconceptualized to incorporate three transformative concepts: teachers play the key role in determining the…

  15. Zika Phase 1 Clinical Trial Material—From Research to Release in 90 Days | FNLCR Staging

    Cancer.gov

    Over the past 12 months, we’ve grown accustomed to seeing Zika in the news. The virus has been linked to thousands of cases of microcephaly in Brazilian babies. Numerous countries, including the United States, have reported Zika-related deaths. And

  16. Dog-Mediated Human Rabies Death, Haiti, 2016

    PubMed Central

    Etheart, Melissa D.; Doty, Jeff; Monroe, Ben; Crowdis, Kelly; Augustin, Pierre Dilius; Blanton, Jesse; Fenelon, Natael

    2016-01-01

    Haiti has experienced numerous barriers to rabies control over the past decades and is one of the remaining Western Hemisphere countries to report dog-mediated human rabies deaths. We describe the circumstances surrounding a reported human rabies death in 2016 as well as barriers to treatment and surveillance reporting. PMID:27767911

  17. Psychological Distress in Refugee Children: A Systematic Review

    ERIC Educational Resources Information Center

    Bronstein, Israel; Montgomery, Paul

    2011-01-01

    Nearly one-quarter of the refugees worldwide are children. There have been numerous studies reporting their levels of psychological distress. The aim of this paper is to review systematically and synthesize the epidemiological research concerning the mental health of refugee children residing in Western countries. A Cochrane Collaboration style…

  18. Developing Relationships with Immigrant Families: Learning by Asking the Right Questions

    ERIC Educational Resources Information Center

    Francis, Grace L.; Haines, Shana J.; Nagro, Sarah A.

    2017-01-01

    Families immigrate to the United States for numerous reasons, including placement by a refugee resettlement agency because of an unsafe country of origin, religious or ethnic persecution, or financial and educational opportunities. Differing cultures and reasons for immigration (e.g., asylum vs. education) result in great variability among…

  19. Montenegro in the PISA Study

    ERIC Educational Resources Information Center

    Milic, Saša

    2011-01-01

    Montenegro, a country that has been in transition for the last two decades, is trying intensively to restructure its socioeconomic system and reform the main social systems, such as the education system, health care, the judicial system, the social welfare system, etc. Numerous strategic documents have been adopted in the past decade emphasising…

  20. Sharka epidemiology and worldwide management strategies: learning lessons to optimize disease control in perennial plants

    USDA-ARS?s Scientific Manuscript database

    Many plant epidemics that cause major economic losses cannot be controlled with pesticides. Among them, sharka epidemics severely affect prunus trees worldwide. Its causal agent, Plum pox virus (PPV;, genus Potyvirus), has been classified as a quarantine pathogen in numerous countries. As a result, ...

  1. K-12 and University Partnerships: Bridging the Advocacy Gap

    ERIC Educational Resources Information Center

    Bryan, Charity; Sims, Sandra

    2011-01-01

    Research has cited numerous advantages and benefits of K-12 collaborations with the larger university community (Castle, Fox, & Souder, 2006; Crocco, Faithfull, & Schwartz, 2003). Departments of kinesiology across the country are well positioned to establish partnerships with local school systems in order to advocate for quality, daily physical…

  2. Orange-fleshed sweet potatoes are an excellent source of vitamin A

    USDA-ARS?s Scientific Manuscript database

    Vitamin A is an essential vitamin required for growth, vision, and immune function. Vitamin A deficiency is a public health problem in numerous countries. 208 million women and children suffer from vitamin A deficiency worldwide. Several carotenoids, including beta-carotene, can be converted to vi...

  3. Dog-Mediated Human Rabies Death, Haiti, 2016.

    PubMed

    Wallace, Ryan M; Etheart, Melissa D; Doty, Jeff; Monroe, Ben; Crowdis, Kelly; Augustin, Pierre Dilius; Blanton, Jesse; Fenelon, Natael

    2016-11-01

    Haiti has experienced numerous barriers to rabies control over the past decades and is one of the remaining Western Hemisphere countries to report dog-mediated human rabies deaths. We describe the circumstances surrounding a reported human rabies death in 2016 as well as barriers to treatment and surveillance reporting.

  4. Inventory of Data Sources in Science and Technology. A Preliminary Survey.

    ERIC Educational Resources Information Center

    International Council of Scientific Unions, Paris (France).

    Provided in this inventory are sources of numerical or factual data in selected fields of basic science and applied science/technology. The objective of the inventory is to provide organizations and individuals (scientists, engineers, and information specialists), particularly those in developing countries, with basic data sources relevant to…

  5. Exploring Partial Order of European Countries

    ERIC Educational Resources Information Center

    Annoni, Paola; Bruggemann, Rainer

    2009-01-01

    Partial Order Theory has been recently more and more employed in applied science to overcome the intrinsic disadvantage hidden in aggregation, if a multiple attribute system is available. Despite its numerous positive features, there are many practical cases where the interpretation of the partial order can be rather troublesome. In these cases…

  6. Massification and Diversification as Complementary Strategies for Economic Growth in Developed and Developing Countries

    ERIC Educational Resources Information Center

    Tyndorf, Darryl; Glass, Chris R.

    2016-01-01

    Numerous microeconomic studies demonstrate the significant individual returns to tertiary education; however, little empirical evidence exists regarding the effects of higher education massification and diversification agendas on long-term macroeconomic growth. The researchers used the Uzawa-Lucas endogenous growth model to tertiary education…

  7. Errors in logic and statistics plague a meta-analysis

    USDA-ARS?s Scientific Manuscript database

    The non-target effects of transgenic insecticidal crops has been a topic of debate for over a decade and many laboratory and field studies have addressed the issue in numerous countries. In 2009 Lovei et al. (Transgenic Insecticidal Crops and Natural Enemies: A Detailed Review of Laboratory Studies)...

  8. Ecological, Psychological, and Cognitive Components of Reading Difficulties: Testing the Component Model of Reading in Fourth Graders across 38 Countries

    ERIC Educational Resources Information Center

    Chiu, Ming Ming; McBride-Chang, Catherine; Lin, Dan

    2012-01-01

    The authors tested the component model of reading (CMR) among 186,725 fourth grade students from 38 countries (45 regions) on five continents by analyzing the 2006 Progress in International Reading Literacy Study data using measures of ecological (country, family, school, teacher), psychological, and cognitive components. More than 91% of the…

  9. A Cross-Cultural Test of the Work-Family Interface in 48 Countries

    ERIC Educational Resources Information Center

    Jeffrey Hill, E.; Yang, Chongming; Hawkins, Alan J.; Ferris, Maria

    2004-01-01

    This study tests a cross-cultural model of the work-family interface. Using multigroup structural equation modeling with IBM survey responses from 48 countries (N= 25,380), results show that the same work-family interface model that fits the data globally also fits the data in a four-group model composed of culturally related groups of countries,…

  10. Measuring the bias against low-income country research: an Implicit Association Test.

    PubMed

    Harris, Matthew; Macinko, James; Jimenez, Geronimo; Mullachery, Pricila

    2017-11-06

    With an increasing array of innovations and research emerging from low-income countries there is a growing recognition that even high-income countries could learn from these contexts. It is well known that the source of a product influences perception of that product, but little research has examined whether this applies also in evidence-based medicine and decision-making. In order to examine likely barriers to learning from low-income countries, this study uses established methods in cognitive psychology to explore whether healthcare professionals and researchers implicitly associate good research with rich countries more so than with poor countries. Computer-based Implicit Association Test (IAT) distributed to healthcare professionals and researchers. Stimuli representing Rich Countries were chosen from OECD members in the top ten (>$36,000 per capita) World Bank rankings and Poor Countries were chosen from the bottom thirty (<$1000 per capita) countries by GDP per capita, in both cases giving attention to regional representation. Stimuli representing Research were descriptors of the motivation (objective/biased), value (useful/worthless), clarity (precise/vague), process (transparent/dishonest), and trustworthiness (credible/unreliable) of research. IAT results are presented as a Cohen's d statistic. Quantile regression was used to assess the contribution of covariates (e.g. age, sex, country of origin) to different values of IAT responses that correspond to different levels of implicit bias. Poisson regression was used to model dichotomized responses to the explicit bias item. Three hundred twenty one tests were completed in a four-week period between March and April 2015. The mean Implicit Association Test result (a standardized mean relative latency between congruent and non-congruent categories) for the sample was 0.57 (95% CI 0.52 to 0.61) indicating that on average our sample exhibited moderately strong implicit associations between Rich Countries and Good Research. People over 40 years of age were less likely to exhibit pro-poor implicit associations, and being a peer reviewer contributes to a more pro-poor association. The majority of our participants associate Good Research with Rich Countries, compared to Poor Countries. Implicit associations such as these might disfavor research from poor countries in research evaluation, evidence-based medicine and diffusion of innovations.

  11. Why aircraft disinsection?

    PubMed Central

    Gratz, N. G.; Steffen, R.; Cocksedge, W.

    2000-01-01

    A serious problem is posed by the inadvertent transport of live mosquitoes aboard aircraft arriving from tropical countries where vector-borne diseases are endemic. Surveys at international airports have found many instances of live insects, particularly mosquitoes, aboard aircraft arriving from countries where malaria and arboviruses are endemic. In some instances mosquito species have been established in countries in which they have not previously been reported. A serious consequence of the transport of infected mosquitoes aboard aircraft has been the numerous cases of "airport malaria" reported from Europe, North America and elsewhere. There is an important on-going need for the disinsection of aircraft coming from airports in tropical disease endemic areas into nonendemic areas. The methods and materials available for use in aircraft disinsection and the WHO recommendations for their use are described. PMID:10994283

  12. Synthesis of national reports for Rio+20

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    2013-01-15

    In the lead up to the United Nations Conference on Sustainable Development (Rio+20), which took place in Brazil in June 2012, there were numerous efforts in countries around the world to help governments, civil society organizations and individuals prepare for the event. One of the more significant efforts led by UNDP in collaboration with the United Nations Department of Economic and Social Affairs (UN DESA) was a support programme to 72 countries across all regions to build a consensus on national views around the themes and objectives of the Rio+20 Conference. This report highlights significant advances in sustainable development frommore » almost 60 country reports and underscores the challenges and bottlenecks to moving beyond the economic-led growth strategies of the past 20 years.« less

  13. Why aircraft disinsection?

    PubMed

    Gratz, N G; Steffen, R; Cocksedge, W

    2000-01-01

    A serious problem is posed by the inadvertent transport of live mosquitoes aboard aircraft arriving from tropical countries where vector-borne diseases are endemic. Surveys at international airports have found many instances of live insects, particularly mosquitoes, aboard aircraft arriving from countries where malaria and arboviruses are endemic. In some instances mosquito species have been established in countries in which they have not previously been reported. A serious consequence of the transport of infected mosquitoes aboard aircraft has been the numerous cases of "airport malaria" reported from Europe, North America and elsewhere. There is an important on-going need for the disinsection of aircraft coming from airports in tropical disease endemic areas into nonendemic areas. The methods and materials available for use in aircraft disinsection and the WHO recommendations for their use are described.

  14. A Mathematical Model of Economic Population Dynamics in a Country That Has Optimal Zakat Management

    NASA Astrophysics Data System (ADS)

    Subhan, M.

    2018-04-01

    Zakat is the main tools against two issues in Islamic economy: economic justice and helping the poor. However, no government of Islamic countries can solve the economic disparity today. A mathematical model could give some understanding about this phenomenon. The goal of this research is to obtain a mathematical model that can describe the dynamic of economic group population. The research is theoretical based on relevance references. From the analytical and numerical simulation, we conclude that well-manage zakat and full comitment of the wealthy can achieve wealth equilibrium that represents minimum poverty.

  15. Quantifying spatial distribution of spurious mixing in ocean models.

    PubMed

    Ilıcak, Mehmet

    2016-12-01

    Numerical mixing is inevitable for ocean models due to tracer advection schemes. Until now, there is no robust way to identify the regions of spurious mixing in ocean models. We propose a new method to compute the spatial distribution of the spurious diapycnic mixing in an ocean model. This new method is an extension of available potential energy density method proposed by Winters and Barkan (2013). We test the new method in lock-exchange and baroclinic eddies test cases. We can quantify the amount and the location of numerical mixing. We find high-shear areas are the main regions which are susceptible to numerical truncation errors. We also test the new method to quantify the numerical mixing in different horizontal momentum closures. We conclude that Smagorinsky viscosity has less numerical mixing than the Leith viscosity using the same non-dimensional constant.

  16. The foamed structures in numerical testing

    NASA Astrophysics Data System (ADS)

    John, Antoni; John, Małgorzata

    2018-01-01

    In the paper numerical simulation of the foamed metal structures using numerical homogenization algorithm is prescribed. From the beginning, numerical model of heterogeneous porous simplified structures of typical foamed metal, based on the FEM was built and material parameters (coefficients of elasticity matrix of the considered structure) were determined with use of numerical homogenization algorithm. During the work the different RVE models of structure were created and their properties were compared at different relative density, different numbers and the size and structure of the arrangement of voids. Finally, obtained results were used in modeling of typical elements made from foam metals structures - sandwich structure and profile filled with metal foam. Simulation were performed for different dimensions of cladding and core. Additionally, the test of influence material orientation (arrangement of voids in RVE element) on the maximum stresses and displacement during bending test was performed.

  17. CIM at GE's factory of the future

    NASA Astrophysics Data System (ADS)

    Waldman, H.

    Functional features of a highly automated aircraft component batch processing factory are described. The system has processing, working, and methodology components. A rotating parts operation installed 20 yr ago features a high density of numerically controlled machines, and is connected to a hierarchical network of data communications and apparatus for moving the rotating parts and tools of engines. Designs produced at one location in the country are sent by telephone link to other sites for development of manufacturing plans, tooling, numerical control programs, and process instructions for the rotating parts. Direct numerical control is implemented at the work stations, which have instructions stored on tape for back-up in case the host computer goes down. Each machine is automatically monitored at 48 points and notice of failure can originate from any point in the system.

  18. Dispersive models describing mosquitoes’ population dynamics

    NASA Astrophysics Data System (ADS)

    Yamashita, W. M. S.; Takahashi, L. T.; Chapiro, G.

    2016-08-01

    The global incidences of dengue and, more recently, zica virus have increased the interest in studying and understanding the mosquito population dynamics. Understanding this dynamics is important for public health in countries where climatic and environmental conditions are favorable for the propagation of these diseases. This work is based on the study of nonlinear mathematical models dealing with the life cycle of the dengue mosquito using partial differential equations. We investigate the existence of traveling wave solutions using semi-analytical method combining dynamical systems techniques and numerical integration. Obtained solutions are validated through numerical simulations using finite difference schemes.

  19. Simulation of a manual electric-arc welding in a working gas pipeline. 2. Numerical investigation of the temperature-stress distribution in the wall of a gas pipe

    NASA Astrophysics Data System (ADS)

    Baikov, V. I.; Gishkelyuk, I. A.; Rus', A. M.; Sidorovich, T. V.; Tonkonogov, B. A.

    2010-11-01

    A numerical simulation of the action of the current experienced by an electric arc and the rate of gas flow in a pipe of a cross-country gas pipeline on the depth of penetration of the electric arc into the wall of this pipe and on the current and residual stresses arising in the pipe material in the process of electric-arc welding of nonthrough cavity-like defects in it has been carried out for gas pipes with walls of different thickness.

  20. Steel Fibers Reinforced Concrete Pipes - Experimental Tests and Numerical Simulation

    NASA Astrophysics Data System (ADS)

    Doru, Zdrenghea

    2017-10-01

    The paper presents in the first part a state of the art review of reinforced concrete pipes used in micro tunnelling realised through pipes jacking method and design methods for steel fibres reinforced concrete. In part two experimental tests are presented on inner pipes with diameters of 1410mm and 2200mm, and specimens (100x100x500mm) of reinforced concrete with metal fibres (35 kg / m3). In part two experimental tests are presented on pipes with inner diameters of 1410mm and 2200mm, and specimens (100x100x500mm) of reinforced concrete with steel fibres (35 kg / m3). The results obtained are analysed and are calculated residual flexural tensile strengths which characterise the post-cracking behaviour of steel fibres reinforced concrete. In the third part are presented numerical simulations of the tests of pipes and specimens. The model adopted for the pipes test was a three-dimensional model and loads considered were those obtained in experimental tests at reaching breaking forces. Tensile stresses determined were compared with mean flexural tensile strength. To validate tensile parameters of steel fibres reinforced concrete, experimental tests of the specimens were modelled with MIDAS program to reproduce the flexural breaking behaviour. To simulate post - cracking behaviour was used the method σ — ε based on the relationship stress - strain, according to RILEM TC 162-TDF. For the specimens tested were plotted F — δ diagrams, which have been superimposed for comparison with the similar diagrams of experimental tests. The comparison of experimental results with those obtained from numerical simulation leads to the following conclusions: - the maximum forces obtained by numerical calculation have higher values than the experimental values for the same tensile stresses; - forces corresponding of residual strengths have very similar values between the experimental and numerical calculations; - generally the numerical model estimates a breaking force greater than that obtained in the experimental tests. Experimental and numerical studies are used to establish the residual characteristic flexural tensile strength minimum guaranteed and limits of applicability of concrete pipes reinforced with steel fibres used in various field and loading situations.

  1. National roll-out of latent tuberculosis testing and treatment for new migrants in England: a retrospective evaluation in a high-incidence area

    PubMed Central

    Loutet, Miranda G.; Burman, Matthew; Jayasekera, Nivenka; Trathen, Duncan; Dart, Susan; Kunst, Heinke; Zenner, Dominik

    2018-01-01

    Latent tuberculosis infection (LTBI) screening is an important intervention for tuberculosis (TB) elimination in low-incidence countries and is, therefore, a key component of England's TB control strategy. This study describes outcomes from a LTBI screening programme in a high-incidence area to inform national LTBI screening in England and other low-incidence countries. We conducted a retrospective cohort study of LTBI screening among eligible migrants (from high-incidence countries and entered the UK within the last 5 years), who were identified at primary-care clinics in Newham, London between August 2014 and August 2015. Multivariable logistic regression was used to identify factors associated with LTBI testing uptake, interferon-γ release assay (IGRA) positivity and treatment uptake. 40% of individuals offered LTBI screening received an IGRA test. The majority of individuals tested were 16–35 years old, male and born in India, Bangladesh or Pakistan. Country of birth, smoking status and co-morbidities were associated with LTBI testing uptake. IGRA positivity was 32% among those tested and was significantly associated with country of birth, age, sex and co-morbidities. This study identifies factors associated with screening uptake, IGRA positivity and treatment uptake, and improves understanding of groups that should be supported to increase acceptability of LTBI testing and treatment in the community. PMID:29326327

  2. Backbone of complex networks of corporations: the flow of control.

    PubMed

    Glattfelder, J B; Battiston, S

    2009-09-01

    We present a methodology to extract the backbone of complex networks based on the weight and direction of links, as well as on nontopological properties of nodes. We show how the methodology can be applied in general to networks in which mass or energy is flowing along the links. In particular, the procedure enables us to address important questions in economics, namely, how control and wealth are structured and concentrated across national markets. We report on the first cross-country investigation of ownership networks, focusing on the stock markets of 48 countries around the world. On the one hand, our analysis confirms results expected on the basis of the literature on corporate control, namely, that in Anglo-Saxon countries control tends to be dispersed among numerous shareholders. On the other hand, it also reveals that in the same countries, control is found to be highly concentrated at the global level, namely, lying in the hands of very few important shareholders. Interestingly, the exact opposite is observed for European countries. These results have previously not been reported as they are not observable without the kind of network analysis developed here.

  3. Backbone of complex networks of corporations: The flow of control

    NASA Astrophysics Data System (ADS)

    Glattfelder, J. B.; Battiston, S.

    2009-09-01

    We present a methodology to extract the backbone of complex networks based on the weight and direction of links, as well as on nontopological properties of nodes. We show how the methodology can be applied in general to networks in which mass or energy is flowing along the links. In particular, the procedure enables us to address important questions in economics, namely, how control and wealth are structured and concentrated across national markets. We report on the first cross-country investigation of ownership networks, focusing on the stock markets of 48 countries around the world. On the one hand, our analysis confirms results expected on the basis of the literature on corporate control, namely, that in Anglo-Saxon countries control tends to be dispersed among numerous shareholders. On the other hand, it also reveals that in the same countries, control is found to be highly concentrated at the global level, namely, lying in the hands of very few important shareholders. Interestingly, the exact opposite is observed for European countries. These results have previously not been reported as they are not observable without the kind of network analysis developed here.

  4. Uranium deposits of Brazil

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    Brazil is a country of vast natural resources, including numerous uranium deposits. In support of the country`s nuclear power program, Brazil has developed the most active uranium industry in South America. Brazil has one operating reactor (Angra 1, a 626-MWe PWR), and two under construction. The country`s economic challenges have slowed the progress of its nuclear program. At present, the Pocos de Caldas district is the only active uranium production. In 1990, the Cercado open-pit mine produced approximately 45 metric tons (MT) U{sub 3}O{sub 8} (100 thousand pounds). Brazil`s state-owned uranium production and processing company, Uranio do Brasil, announced itmore » has decided to begin shifting its production from the high-cost and nearly depleted deposits at Pocos de Caldas, to lower-cost reserves at Lagoa Real. Production at Lagoa Real is schedules to begin by 1993. In addition to these two districts, Brazil has many other known uranium deposits, and as a whole, it is estimated that Brazil has over 275,000 MT U{sub 3}O{sub 8} (600 million pounds U{sub 3}O{sub 8}) in reserves.« less

  5. Non-hydrostatic semi-elastic hybrid-coordinate SISL extension of HIRLAM. Part II: numerical testing

    NASA Astrophysics Data System (ADS)

    Rõõm, Rein; Männik, Aarne; Luhamaa, Andres; Zirk, Marko

    2007-10-01

    The semi-implicit semi-Lagrangian (SISL), two-time-level, non-hydrostatic numerical scheme, based on the non-hydrostatic, semi-elastic pressure-coordinate equations, is tested in model experiments with flow over given orography (elliptical hill, mountain ridge, system of successive ridges) in a rectangular domain with emphasis on the numerical accuracy and non-hydrostatic effect presentation capability. Comparison demonstrates good (in strong primary wave generation) to satisfactory (in weak secondary wave reproduction in some cases) consistency of the numerical modelling results with known stationary linear test solutions. Numerical stability of the developed model is investigated with respect to the reference state choice, modelling dynamics of a stationary front. The horizontally area-mean reference temperature proves to be the optimal stability warrant. The numerical scheme with explicit residual in the vertical forcing term becomes unstable for cross-frontal temperature differences exceeding 30 K. Stability is restored, if the vertical forcing is treated implicitly, which enables to use time steps, comparable with the hydrostatic SISL.

  6. Development of early numerical abilities of Spanish-speaking Mexican preschoolers: A new assessment tool.

    PubMed

    Beltrán-Navarro, Beatriz; Abreu-Mendoza, Roberto A; Matute, Esmeralda; Rosselli, Monica

    2018-01-01

    This article presents a tool for assessing the early numerical abilities of Spanish-speaking Mexican preschoolers. The Numerical Abilities Test, from the Evaluación Neuropsicológica Infantil-Preescolar (ENI-P), evaluates four core abilities of number development: magnitude comparison, counting, subitizing, and basic calculation. We evaluated 307 Spanish-speaking Mexican children aged 2 years 6 months to 4 years 11 months. Appropriate internal consistency and test-retest reliability were demonstrated. We also investigated the effect of age, children's school attendance, maternal education, and sex on children's numerical scores. The results showed that the four subtests captured development across ages. Critically, maternal education had an impact on children's performance in three out of the four subtests, but there was no effect associated with children's school attendance or sex. These results suggest that the Numerical Abilities Test is a reliable instrument for Spanish-speaking preschoolers. We discuss the implications of our outcomes for numerical development.

  7. Comparison of eigenvectors for coupled seismo-electromagnetic layered-Earth modelling

    NASA Astrophysics Data System (ADS)

    Grobbe, N.; Slob, E. C.; Thorbecke, J. W.

    2016-07-01

    We study the accuracy and numerical stability of three eigenvector sets for modelling the coupled poroelastic and electromagnetic layered-Earth response. We use a known eigenvector set, its flux-normalized version and a newly derived flux-normalized set. The new set is chosen such that the system is properly uncoupled when the coupling between the poroelastic and electromagnetic fields vanishes. We carry out two different numerical stability tests: the first test focuses on the internal system, eigenvector and eigenvalue consistency; the second test investigates the stability and preciseness of the flux-normalized systems by looking at identity relations. We find that the known set shows the largest deviation for both tests, whereas the new set performs best. In two additional numerical modelling experiments, these numerical inaccuracies are shown to generate numerical noise levels comparable to small signals, such as signals coming from the important interface conversion responses, especially when the coupling coefficient is small. When coupling vanishes completely, the known set does not produce proper results. The new set produces numerically stable and accurate results in all situations. We therefore strongly recommend to use this newly derived set for future layered-Earth seismo-electromagnetic modelling experiments.

  8. Definition of sanitary boundaries to prevent ISAv spread between salmon farms in southern Chile based on numerical simulations of currents

    NASA Astrophysics Data System (ADS)

    Olivares, Gonzalo; Sepúlveda, H. H.; Yannicelli, B.

    2015-06-01

    The infectious Salmon Anemia virus (ISAv) is a pathogen that mainly affects the Atlantic Salmon (Salmo salar). It was detected in Norway in 1984 and in June 2007 appeared in Chile, producing a drop of more than 30% in the country's production level. It is expected that with certain regularity, outbreaks will continue to appear in Chile without the need of reintroducing the virus from foreign countries. We present a numerical study of the influence of winds and tides in the dispersion of lagrangian particles to simulate the transport of ISAv in the Aysen region, in southern Chile. This study combines the use of numerical models of the ocean and atmosphere, lagrangian tracking and biological aspects of ISAv infections. As in previous results, a wider dispersion of ISAv was observed during spring tides. Temporal changes in wind significantly modified the transport of viral particles from an infected center. Under similar forcing conditions, the areas of risk associated to culture sites separated by a few kilometers could be very different. Our main results remark the importance of the use of a detailed knowledge of hydrographic and atmospheric circulation in the definition of boundaries for sanitary management areas. We suggest that a methodology similar to the one presented in this study should be considered to define sanitary strategies to minimize the occurrence of native outbreaks of ISAv.

  9. [Dog tourism and import: an inquiry in Germany on the extent as well as on the spectrum and preference of countries of residence and origin respectively].

    PubMed

    Glaser, B; Gothe, R

    1998-05-01

    A survey was conducted among practicing veterinarians and at pet clinics in Germany in order to estimate the extent of tourism with dogs and import of dogs and to determine the range and preference of the foreign countries involved. The survey covered the years from 1985 to 1995 and included 5240 dogs, of which 4567 (87.2%) were born in Germany and 673 (12.8%) were born abroad. Among the latter, 263 (39.1%) originated from Mediterranean countries and Portugal, 344 (51.1%) were born in other European countries and 66 (9.8%) were from non-European countries. Of all 5240 dogs surveyed, 2894 (55.2%) had been taken abroad at least once between 1985 and 1995. Of these, 2424 (53.1%) were born in Germany, 470 (69.8%) were born abroad. Of the 2894 dogs taken abroad, 1929 (66.7%) travelled to Mediterranean countries or Portugal and 1152 of these had additional travels to other countries as well. The spectrum of all countries travelled to was very broad, but numerous dogs were taken regularly, repeatedly and exclusively to Austria, Switzerland, Italy, Spain or France. Other countries were visited only once for the majority of dogs. The analysis of the annual survey data revealed a steady increase of dogs along on trips from Germany to other countries, rising from 31.1% in 1990 to 40.8% in 1994. In any of these years, always more than 56% of these dogs were taken to Mediterranean countries.

  10. Health and Ethical Consequences of Outsourcing Pivotal Clinical Trials to Latin America: A Cross-Sectional, Descriptive Study.

    PubMed

    Homedes, Núria; Ugalde, Antonio

    2016-01-01

    The implications of conducting clinical trials in low and middle income countries on the financial accessibility and safety of the pharmaceutical products available in those markets have not been studied. Regulatory practices and ethical declarations lead to the commercialization of the new products, referred to as New Molecular Entities (NMEs), in the countries where tested as soon as they are approved in high surveillance countries. Patients and patients' associations use the Latin American courts to access new and expensive treatments, regardless of their safety profile and therapeutic value. Cross-sectional, descriptive study. To determine the therapeutic value and safety profile of the NMEs approved by the Food and Drug Administration (FDA) in 2011 and 2012 that had been tested in Latin America, and the implications of their market approval for the pharmaceutical budgets in the countries where tested. Latin America. To assess the therapeutic value and safety of the NMEs commercialized in the different countries we used f independent drug bulletins. The prices of the NMEs for the consumers were obtained from the pharmaceutical price observatories of the countries were the medicines had been tested. If the price was not available in the observatories, it was obtained from pharmaceutical distributors. We used the countries' minimum wage and per capita income to calculate the financial accessibility of a course of treatment with the NMEs. We found that 33 NMEs approved by the FDA in 2011 and 2012 have been tested in Latin America. Of these, 26 had been evaluated by independent drug bulletins and only five were found to add some value to a subset of patients and had significant side-effects. The pharmaceutical prices were very high, varied widely across countries and were unrelated to the countries' income per capita or minimum wage. The implementation of clinical trials in Latin America results in the commercialization of medicines with questionable safety profiles and limited therapeutic value, putting patients at risk and causing budgetary strains in pharmaceutical budgets.

  11. Introducing Simple Detection of Bioavailable Arsenic at Rafaela (Santa Fe Province, Argentina) Using the ARSOlux Biosensor.

    PubMed

    Siegfried, Konrad; Hahn-Tomer, Sonja; Koelsch, Andreas; Osterwalder, Eva; Mattusch, Juergen; Staerk, Hans-Joachim; Meichtry, Jorge M; De Seta, Graciela E; Reina, Fernando D; Panigatti, Cecilia; Litter, Marta I; Harms, Hauke

    2015-05-21

    Numerous articles have reported the occurrence of arsenic in drinking water in Argentina, and the resulting health effects in severely affected regions of the country. Arsenic in drinking water in Argentina is largely naturally occurring due to elevated background content of the metalloid in volcanic sediments, although, in some regions, mining can contribute. While the origin of arsenic release has been discussed extensively, the problem of drinking water contamination has not yet been solved. One key step in progress towards mitigation of problems related with the consumption of As-containing water is the availability of simple detection tools. A chemical test kit and the ARSOlux biosensor were evaluated as simple analytical tools for field measurements of arsenic in the groundwater of Rafaela (Santa Fe, Argentina), and the results were compared with ICP-MS and HPLC-ICP-MS measurements. A survey of the groundwater chemistry was performed to evaluate possible interferences with the field tests. The results showed that the ARSOlux biosensor performed better than the chemical field test, that the predominant species of arsenic in the study area was arsenate and that arsenic concentration in the studied samples had a positive correlation with fluoride and vanadium, and a negative one with calcium and iron.

  12. Difficulties in initial algebra learning in Indonesia

    NASA Astrophysics Data System (ADS)

    Jupri, Al; Drijvers, Paul; van den Heuvel-Panhuizen, Marja

    2014-12-01

    Within mathematics curricula, algebra has been widely recognized as one of the most difficult topics, which leads to learning difficulties worldwide. In Indonesia, algebra performance is an important issue. In the Trends in International Mathematics and Science Study (TIMSS) 2007, Indonesian students' achievement in the algebra domain was significantly below the average student performance in other Southeast Asian countries such as Thailand, Malaysia, and Singapore. This fact gave rise to this study which aims to investigate Indonesian students' difficulties in algebra. In order to do so, a literature study was carried out on students' difficulties in initial algebra. Next, an individual written test on algebra tasks was administered, followed by interviews. A sample of 51 grade VII Indonesian students worked the written test, and 37 of them were interviewed afterwards. Data analysis revealed that mathematization, i.e., the ability to translate back and forth between the world of the problem situation and the world of mathematics and to reorganize the mathematical system itself, constituted the most frequently observed difficulty in both the written test and the interview data. Other observed difficulties concerned understanding algebraic expressions, applying arithmetic operations in numerical and algebraic expressions, understanding the different meanings of the equal sign, and understanding variables. The consequences of these findings on both task design and further research in algebra education are discussed.

  13. Introducing Simple Detection of Bioavailable Arsenic at Rafaela (Santa Fe Province, Argentina) Using the ARSOlux Biosensor

    PubMed Central

    Siegfried, Konrad; Hahn-Tomer, Sonja; Koelsch, Andreas; Osterwalder, Eva; Mattusch, Juergen; Staerk, Hans-Joachim; Meichtry, Jorge M.; De Seta, Graciela E.; Reina, Fernando D.; Panigatti, Cecilia; Litter, Marta I.; Harms, Hauke

    2015-01-01

    Numerous articles have reported the occurrence of arsenic in drinking water in Argentina, and the resulting health effects in severely affected regions of the country. Arsenic in drinking water in Argentina is largely naturally occurring due to elevated background content of the metalloid in volcanic sediments, although, in some regions, mining can contribute. While the origin of arsenic release has been discussed extensively, the problem of drinking water contamination has not yet been solved. One key step in progress towards mitigation of problems related with the consumption of As-containing water is the availability of simple detection tools. A chemical test kit and the ARSOlux biosensor were evaluated as simple analytical tools for field measurements of arsenic in the groundwater of Rafaela (Santa Fe, Argentina), and the results were compared with ICP-MS and HPLC-ICP-MS measurements. A survey of the groundwater chemistry was performed to evaluate possible interferences with the field tests. The results showed that the ARSOlux biosensor performed better than the chemical field test, that the predominant species of arsenic in the study area was arsenate and that arsenic concentration in the studied samples had a positive correlation with fluoride and vanadium, and a negative one with calcium and iron. PMID:26006123

  14. Computerized Numerical Control Test Item Bank.

    ERIC Educational Resources Information Center

    Reneau, Fred; And Others

    This guide contains 285 test items for use in teaching a course in computerized numerical control. All test items were reviewed, revised, and validated by incumbent workers and subject matter instructors. Items are provided for assessing student achievement in such aspects of programming and planning, setting up, and operating machines with…

  15. Economic Literacy in German Speaking Countries and the United States. First Steps to a Comparative Study.

    ERIC Educational Resources Information Center

    Beck, Klaus; Krumm, Volker

    The lack of a German language testing instrument for economic literacy has led to problems for researchers in German-speaking countries to establish the level of economic literacy in those countries. The translation of the 23rd edition (1987) of the Test of Economic Literacy (TEL) into a German version, known as the Wirtschalfliche Bildung Test…

  16. Systemic Measures and Legislative and Organizational Frameworks Aimed at Preventing or Mitigating Drug Shortages in 28 European and Western Asian Countries.

    PubMed

    Bochenek, Tomasz; Abilova, Vafa; Alkan, Ali; Asanin, Bogdan; de Miguel Beriain, Iñigo; Besovic, Zeljka; Vella Bonanno, Patricia; Bucsics, Anna; Davidescu, Michal; De Weerdt, Elfi; Duborija-Kovacevic, Natasa; Fürst, Jurij; Gaga, Mina; Gailīte, Elma; Gulbinovič, Jolanta; Gürpınar, Emre U; Hankó, Balázs; Hargaden, Vincent; Hotvedt, Tor A; Hoxha, Iris; Huys, Isabelle; Inotai, Andras; Jakupi, Arianit; Jenzer, Helena; Joppi, Roberta; Laius, Ott; Lenormand, Marie-Camille; Makridaki, Despina; Malaj, Admir; Margus, Kertu; Marković-Peković, Vanda; Miljković, Nenad; de Miranda, João L; Primožič, Stanislav; Rajinac, Dragana; Schwartz, David G; Šebesta, Robin; Simoens, Steven; Slaby, Juraj; Sović-Brkičić, Ljiljana; Tesar, Tomas; Tzimis, Leonidas; Warmińska, Ewa; Godman, Brian

    2017-01-01

    Drug shortages have been identified as a public health problem in an increasing number of countries. This can negatively impact on the quality and efficiency of patient care, as well as contribute to increases in the cost of treatment and the workload of health care providers. Shortages also raise ethical and political issues. The scientific evidence on drug shortages is still scarce, but many lessons can be drawn from cross-country analyses. The objective of this study was to characterize, compare, and evaluate the current systemic measures and legislative and organizational frameworks aimed at preventing or mitigating drug shortages within health care systems across a range of European and Western Asian countries. The study design was retrospective, cross-sectional, descriptive, and observational. Information was gathered through a survey distributed among senior personnel from ministries of health, state medicines agencies, local health authorities, other health or pharmaceutical pricing and reimbursement authorities, health insurance companies and academic institutions, with knowledge of the pharmaceutical markets in the 28 countries studied. Our study found that formal definitions of drug shortages currently exist in only a few countries. The characteristics of drug shortages, including their assortment, duration, frequency, and dynamics, were found to be variable and sometimes difficult to assess. Numerous information hubs were identified. Providing public access to information on drug shortages to the maximum possible extent is a prerequisite for performing more advanced studies on the problem and identifying solutions. Imposing public service obligations, providing the formal possibility to prescribe unlicensed medicines, and temporary bans on parallel exports are widespread measures. A positive finding of our study was the identification of numerous bottom-up initiatives and organizational frameworks aimed at preventing or mitigating drug shortages. The experiences and lessons drawn from these initiatives should be carefully evaluated, monitored, and presented to a wider international audience for careful appraisal. To be able to find solutions to the problem of drug shortages, there is an urgent need to develop a set of agreed definitions for drug shortages, as well as methodologies for their evaluation and monitoring. This is being progressed.

  17. Systemic Measures and Legislative and Organizational Frameworks Aimed at Preventing or Mitigating Drug Shortages in 28 European and Western Asian Countries

    PubMed Central

    Bochenek, Tomasz; Abilova, Vafa; Alkan, Ali; Asanin, Bogdan; de Miguel Beriain, Iñigo; Besovic, Zeljka; Vella Bonanno, Patricia; Bucsics, Anna; Davidescu, Michal; De Weerdt, Elfi; Duborija-Kovacevic, Natasa; Fürst, Jurij; Gaga, Mina; Gailīte, Elma; Gulbinovič, Jolanta; Gürpınar, Emre U.; Hankó, Balázs; Hargaden, Vincent; Hotvedt, Tor A.; Hoxha, Iris; Huys, Isabelle; Inotai, Andras; Jakupi, Arianit; Jenzer, Helena; Joppi, Roberta; Laius, Ott; Lenormand, Marie-Camille; Makridaki, Despina; Malaj, Admir; Margus, Kertu; Marković-Peković, Vanda; Miljković, Nenad; de Miranda, João L.; Primožič, Stanislav; Rajinac, Dragana; Schwartz, David G.; Šebesta, Robin; Simoens, Steven; Slaby, Juraj; Sović-Brkičić, Ljiljana; Tesar, Tomas; Tzimis, Leonidas; Warmińska, Ewa; Godman, Brian

    2018-01-01

    Drug shortages have been identified as a public health problem in an increasing number of countries. This can negatively impact on the quality and efficiency of patient care, as well as contribute to increases in the cost of treatment and the workload of health care providers. Shortages also raise ethical and political issues. The scientific evidence on drug shortages is still scarce, but many lessons can be drawn from cross-country analyses. The objective of this study was to characterize, compare, and evaluate the current systemic measures and legislative and organizational frameworks aimed at preventing or mitigating drug shortages within health care systems across a range of European and Western Asian countries. The study design was retrospective, cross-sectional, descriptive, and observational. Information was gathered through a survey distributed among senior personnel from ministries of health, state medicines agencies, local health authorities, other health or pharmaceutical pricing and reimbursement authorities, health insurance companies and academic institutions, with knowledge of the pharmaceutical markets in the 28 countries studied. Our study found that formal definitions of drug shortages currently exist in only a few countries. The characteristics of drug shortages, including their assortment, duration, frequency, and dynamics, were found to be variable and sometimes difficult to assess. Numerous information hubs were identified. Providing public access to information on drug shortages to the maximum possible extent is a prerequisite for performing more advanced studies on the problem and identifying solutions. Imposing public service obligations, providing the formal possibility to prescribe unlicensed medicines, and temporary bans on parallel exports are widespread measures. A positive finding of our study was the identification of numerous bottom-up initiatives and organizational frameworks aimed at preventing or mitigating drug shortages. The experiences and lessons drawn from these initiatives should be carefully evaluated, monitored, and presented to a wider international audience for careful appraisal. To be able to find solutions to the problem of drug shortages, there is an urgent need to develop a set of agreed definitions for drug shortages, as well as methodologies for their evaluation and monitoring. This is being progressed. PMID:29403372

  18. Exploring differential item functioning (DIF) with the Rasch model: a comparison of gender differences on eighth grade science items in the United States and Spain.

    PubMed

    Babiar, Tasha Calvert

    2011-01-01

    Traditionally, women and minorities have not been fully represented in science and engineering. Numerous studies have attributed these differences to gaps in science achievement as measured by various standardized tests. Rather than describe mean group differences in science achievement across multiple cultures, this study focused on an in-depth item-level analysis across two countries: Spain and the United States. This study investigated eighth-grade gender differences on science items across the two countries. A secondary purpose of the study was to explore the nature of gender differences using the many-faceted Rasch Model as a way to estimate gender DIF. A secondary analysis of data from the Third International Mathematics and Science Study (TIMSS) was used to address three questions: 1) Does gender DIF in science achievement exist? 2) Is there a relationship between gender DIF and characteristics of the science items? 3) Do the relationships between item characteristics and gender DIF in science items replicate across countries. Participants included 7,087 eight grade students from the United States and 3,855 students from Spain who participated in TIMSS. The Facets program (Linacre and Wright, 1992) was used to estimate gender DIF. The results of the analysis indicate that the content of the item seemed to be related to gender DIF. The analysis also suggests that there is a relationship between gender DIF and item format. No pattern of gender DIF related to cognitive demand was found. The general pattern of gender DIF was similar across the two countries used in the analysis. The strength of item-level analysis as opposed to group mean difference analysis is that gender differences can be detected at the item level, even when no mean differences can be detected at the group level.

  19. Development of risk reduction behavioral counseling for Ebola virus disease survivors enrolled in the Sierra Leone Ebola Virus Persistence Study, 2015-2016

    PubMed Central

    Malik, Tasneem; Ariyarajah, Archchun; Ongpin, Patricia; Hogben, Matthew; McDonald, Suzanna L. R.; Marrinan, Jaclyn; Massaquoi, Thomas; Thorson, Anna; Ervin, Elizabeth; Bernstein, Kyle; Ross, Christine; Liu, William J.; Kroeger, Karen; Durski, Kara N.; Broutet, Nathalie; Knust, Barbara; Deen, Gibrilla F.

    2017-01-01

    Background During the 2014–2016 West Africa Ebola Virus Disease (EVD) epidemic, the public health community had concerns that sexual transmission of the Ebola virus (EBOV) from EVD survivors was a risk, due to EBOV persistence in body fluids of EVD survivors, particularly semen. The Sierra Leone Ebola Virus Persistence Study was initiated to investigate this risk by assessing EBOV persistence in numerous body fluids of EVD survivors and providing risk reduction counseling based on test results for semen, vaginal fluid, menstrual blood, urine, rectal fluid, sweat, tears, saliva, and breast milk. This publication describes implementation of the counseling protocol and the key lessons learned. Methodology/Principal findings The Ebola Virus Persistence Risk Reduction Behavioral Counseling Protocol was developed from a framework used to prevent transmission of HIV and other sexually transmitted infections. The framework helped to identify barriers to risk reduction and facilitated the development of a personalized risk-reduction plan, particularly around condom use and abstinence. Pre-test and post-test counseling sessions included risk reduction guidance, and post-test counseling was based on the participants’ individual test results. The behavioral counseling protocol enabled study staff to translate the study’s body fluid test results into individualized information for study participants. Conclusions/Significance The Ebola Virus Persistence Risk Reduction Behavioral Counseling Protocol provided guidance to mitigate the risk of EBOV transmission from EVD survivors. It has since been shared with and adapted by other EVD survivor body fluid testing programs and studies in Ebola-affected countries. PMID:28892490

  20. Variational Algorithms for Test Particle Trajectories

    NASA Astrophysics Data System (ADS)

    Ellison, C. Leland; Finn, John M.; Qin, Hong; Tang, William M.

    2015-11-01

    The theory of variational integration provides a novel framework for constructing conservative numerical methods for magnetized test particle dynamics. The retention of conservation laws in the numerical time advance captures the correct qualitative behavior of the long time dynamics. For modeling the Lorentz force system, new variational integrators have been developed that are both symplectic and electromagnetically gauge invariant. For guiding center test particle dynamics, discretization of the phase-space action principle yields multistep variational algorithms, in general. Obtaining the desired long-term numerical fidelity requires mitigation of the multistep method's parasitic modes or applying a discretization scheme that possesses a discrete degeneracy to yield a one-step method. Dissipative effects may be modeled using Lagrange-D'Alembert variational principles. Numerical results will be presented using a new numerical platform that interfaces with popular equilibrium codes and utilizes parallel hardware to achieve reduced times to solution. This work was supported by DOE Contract DE-AC02-09CH11466.

  1. International assessment on quality and content of internet information on osteoarthritis.

    PubMed

    Varady, N H; Dee, E C; Katz, J N

    2018-05-23

    Osteoarthritis is one of the leading causes of global disability. Numerous studies have assessed the quality and content of online health information; however, how information content varies between multiple countries remains unknown. The primary objective of this study was to examine how the quality and content of online health information on osteoarthritis compares on an international scale. Internet searches for the equivalent of "knee osteoarthritis treatment" were performed in ten countries around the world. For each country, the first ten websites were evaluated using a custom scoring form examining: website type; quality and reliability using the DISCERN and Health-on-the-Net (HON) frameworks; and treatment content based on three international osteoarthritis treatment guidelines. Consistency of search results between countries speaking the same language was also assessed. Significant differences in all scoring metrics existed between countries speaking different languages. Western countries scored higher than more eastern countries, there were no differences between the United States and Mexico in any of the scoring metrics, and HON certified websites were of higher quality and reliability. Searches in different countries speaking the same language had at least 70% overlap. The quality of online health information on knee osteoarthritis varies significantly between countries speaking different languages. Differential access to quality, accurate, and safe health information online may represent a novel but important health inequality. Future efforts are needed to translate online health resources into additional languages. In the interim, patients may seek websites that display the HON seal. Copyright © 2018. Published by Elsevier Ltd.

  2. Regional gastrointestinal transit and pH studied in 215 healthy volunteers using the wireless motility capsule: influence of age, gender, study country and testing protocol.

    PubMed

    Wang, Y T; Mohammed, S D; Farmer, A D; Wang, D; Zarate, N; Hobson, A R; Hellström, P M; Semler, J R; Kuo, B; Rao, S S; Hasler, W L; Camilleri, M; Scott, S M

    2015-09-01

    The wireless motility capsule (WMC) offers the ability to investigate luminal gastrointestinal (GI) physiology in a minimally invasive manner. To investigate the effect of testing protocol, gender, age and study country on regional GI transit times and associated pH values using the WMC. Regional GI transit times and pH values were determined in 215 healthy volunteers from USA and Sweden studied using the WMC over a 6.5-year period. The effects of test protocol, gender, age and study country were examined. For GI transit times, testing protocol was associated with differences in gastric emptying time (GET; shorter with protocol 2 (motility capsule ingested immediately after meal) vs. protocol 1 (motility capsule immediately before): median difference: 52 min, P = 0.0063) and colonic transit time (CTT; longer with protocol 2: median 140 min, P = 0.0189), but had no overall effect on whole gut transit time. Females had longer GET (by median 17 min, P = 0.0307), and also longer CTT by (104 min, P = 0.0285) and whole gut transit time by (263 min, P = 0.0077). Increasing age was associated with shorter small bowel transit time (P = 0.002), and study country also influenced small bowel and CTTs. Whole gut and CTTs showed clustering of data at values separated by 24 h, suggesting that describing these measures as continuous variables is invalid. Testing protocol, gender and study country also significantly influenced pH values. Regional GI transit times and pH values, delineated using the wireless motility capsule (WMC), vary based on testing protocol, gender, age and country. Standardisation of testing is crucial for cross-referencing in clinical practice and future research. © 2015 John Wiley & Sons Ltd.

  3. ITEM ANALYSIS OF THREE SPANISH NAMING TESTS: A CROSS-CULTURAL INVESTIGATION

    PubMed Central

    de la Plata, Carlos Marquez; Arango-Lasprilla, Juan Carlos; Alegret, Montse; Moreno, Alexander; Tárraga, Luis; Lara, Mar; Hewlitt, Margaret; Hynan, Linda; Cullum, C. Munro

    2009-01-01

    Neuropsychological evaluations conducted in the United States and abroad commonly include the use of tests translated from English to Spanish. The use of translated naming tests for evaluating predominately Spanish-speakers has recently been challenged on the grounds that translating test items may compromise a test’s construct validity. The Texas Spanish Naming Test (TNT) has been developed in Spanish specifically for use with Spanish-speakers; however, it is unlikely patients from diverse Spanish-speaking geographical regions will perform uniformly on a naming test. The present study evaluated and compared the internal consistency and patterns of item-difficulty and -discrimination for the TNT and two commonly used translated naming tests in three countries (i.e., United States, Colombia, Spain). Two hundred fifty two subjects (126 demented, 116 nondemented) across three countries were administered the TNT, Modified Boston Naming Test-Spanish, and the naming subtest from the CERAD. The TNT demonstrated superior internal consistency to its counterparts, a superior item difficulty pattern than the CERAD naming test, and a superior item discrimination pattern than the MBNT-S across countries. Overall, all three Spanish naming tests differentiated nondemented and moderately demented individuals, but the results suggest the items of the TNT are most appropriate to use with Spanish-speakers. Preliminary normative data for the three tests examined in each country are provided. PMID:19208960

  4. Numerical Modelling of Femur Fracture and Experimental Validation Using Bone Simulant.

    PubMed

    Marco, Miguel; Giner, Eugenio; Larraínzar-Garijo, Ricardo; Caeiro, José Ramón; Miguélez, María Henar

    2017-10-01

    Bone fracture pattern prediction is still a challenge and an active field of research. The main goal of this article is to present a combined methodology (experimental and numerical) for femur fracture onset analysis. Experimental work includes the characterization of the mechanical properties and fracture testing on a bone simulant. The numerical work focuses on the development of a model whose material properties are provided by the characterization tests. The fracture location and the early stages of the crack propagation are modelled using the extended finite element method and the model is validated by fracture tests developed in the experimental work. It is shown that the accuracy of the numerical results strongly depends on a proper bone behaviour characterization.

  5. Top Ten Standardized Tests Used Internationally with Children and Youth by School Psychologists in 64 Countries: A 24-Year Follow-Up Study

    ERIC Educational Resources Information Center

    Oakland, Thomas; Douglas, Sara; Kane, Harrison

    2016-01-01

    This article provides a 24-year update on the 10 standardized tests used most frequently with children and youth by school psychologists. Data were acquired from 64 countries through an international survey, with one respondent from each country. The informants were solicited due to their expertise in the area of assessment. The data from the…

  6. a-Copaene and quercivorol lures: Chemical analysis and efficacy for detection of Euwallacea nr. fornicatus (Coleoptera: Curculionidae: Scolytinae)

    USDA-ARS?s Scientific Manuscript database

    Invasive ambrosia beetles in the Euwallacea nr. fornicatus complex vector a fungal pathogen responsible for Fusarium dieback, a disease that impacts avocado (Persea americana) and numerous native trees in the USA, Israel, and other countries. Currently, these pests are detected with quercivorol lure...

  7. Decent Leadership

    ERIC Educational Resources Information Center

    Denton, D. Keith

    2010-01-01

    95% of people surveyed say honesty and integrity are extremely important or very important in being a good leader. That there has been a continuing erosion of trust across numerous business sectors in this country. Nearly 70% of the surveyed respondents said, "I don't know whom to trust anymore", and said they will "hold business to a higher…

  8. Motivation for Weight-Loss Diets: A Clustering, Longitudinal Field Study Using Self-Esteem and Self-Determination Theory Perspectives

    ERIC Educational Resources Information Center

    Georgiadis, Manolis M.; Biddle, Stuart J. H.; Stavrou, Nektarios A.

    2006-01-01

    Background: Gradual elevation of body weight leads numerous individuals to dieting and weight loss behaviours. Nevertheless, the prevalence of obesity continues to rise in industrialised countries. The examination of the motivational determinants of dietary modification ("dieting") in order to identify clusters of individuals in the…

  9. Teacher Management and Educational Reforms: Paradigm Shifts

    ERIC Educational Resources Information Center

    Cheng, Yin Cheong

    2009-01-01

    In the past 15 years, numerous reforms and initiatives in many countries in the Asia-Pacific region have aimed to change education and promote new learning to prepare the new generation for the future. Unfortunately, despite good intentions and huge investments of resources, many of these reforms have been found to be ineffective and…

  10. Re-Framing Pacific Regional Service Delivery: Opportunity Spaces for "Together" and "Apart"

    ERIC Educational Resources Information Center

    Sanga, Kabini

    2011-01-01

    Regionalism is a common development strategy in the Pacific region. Through it, numerous services are delivered to countries, communities and organisations. While some see regionalism as an effective and efficient strategy for the Pacific region, others point to its dismal performance. Using the experience of the Rethinking Pacific Education…

  11. Exploring the Quality of Teacher-Child Interactions: The Soka Discourse in Practice

    ERIC Educational Resources Information Center

    Ikegami, Kiiko; Rivalland, Corine

    2016-01-01

    Numerous research has shown that quality of interactions between early childhood teachers and children contribute significantly to children's holistic development. Most literature on this topic comes from developed/Western countries and little is known about the kind of interactions occurring within the Soka kindergarten model. This article, based…

  12. Designing Media and ICT Strategies for Non-Formal Education in Eritrea

    ERIC Educational Resources Information Center

    Murthy, C. S. H. N.

    2006-01-01

    Designing media and ICT strategies for a newly formed country like Eritrea, which has endured 30 years of armed struggle, leading to massive destruction followed by serial drought, is fraught with numerous constraints: limitation of human resources (e.g. qualified personnel), infrastructure and financial constraints. At the same time, though it…

  13. Unintended Revelations in History Textbooks: The Precarious Authenticity and Historical Continuity of the Slovak Nation

    ERIC Educational Resources Information Center

    Šulíková, Jana

    2016-01-01

    Purpose: This article proposes an analytical framework that helps to identify and challenge misconceptions of ethnocentrism found in pre-tertiary teaching resources for history and the social sciences in numerous countries. Design: Drawing on nationalism studies, the analytical framework employs ideas known under the umbrella terms of…

  14. Little Orphan Annie

    ERIC Educational Resources Information Center

    Hyatt, Sarah

    2009-01-01

    The benefits of therapeutic riding and hippotherapy can be numerous and long lasting for children and adults with special needs. The connection that a child or adult with disabilities can make with a horse is evident in therapeutic riding programs all over the country. In this article, the author, who is the Equestrian Center Director at Heartland…

  15. Permeability between VET and Higher Education--A Way of Human Resource Development

    ERIC Educational Resources Information Center

    Spottl, Georg

    2013-01-01

    Purpose: Parity of esteem between general and vocational education is a widely discussed topic in those countries which have established a system of vocational education and training (VET) beside the system of general education, leading to numerous qualifications and licenses. This paper aims to address this issue. Design/methodology/approach: An…

  16. Zika Phase 1 Clinical Trial Material—From Research to Release in 90 Days | Frederick National Laboratory for Cancer Research

    Cancer.gov

    Over the past 12 months, we’ve grown accustomed to seeing Zika in the news. The virus has been linked to thousands of cases of microcephaly in Brazilian babies. Numerous countries, including the United States, have reported Zika-related deaths. And

  17. Supporting the Retention of Non-Traditional Students in Higher Education Using a Resilience Framework

    ERIC Educational Resources Information Center

    Cotton, Debby R. E.; Nash, Tricia; Kneale, Pauline

    2017-01-01

    Student drop-out in higher education is an increasingly important issue across Europe, but there are substantial disparities between countries and institutions which suggest that variations in policies and practices may influence student retention and success. Numerous schemes have been devised to increase student retention, frequently focusing on…

  18. Influences of Some Philosophical Approaches in the Historical Development of Turkish Science Education

    ERIC Educational Resources Information Center

    Turkmen, Lutfullah; Bonnstetter, Ronald J.

    2007-01-01

    The last one thousand years or more of Turkish science educational development have numerous historical similarities to other parts of the world. While documentation of historical educational developments are important to those whose ancestors are being described, the true value of this regional- and country-specific evolutionary historical…

  19. A Critical and Contextual Approach to Inclusive Education: Perspectives from an Indian Context

    ERIC Educational Resources Information Center

    Taneja Johansson, Shruti

    2014-01-01

    Post Salamanca, inclusive education was incorporated in government policies in countries of the North and South. Since then there have been numerous books, articles, and academic debates on the topic but with little representation from the South. This article examines how inclusive education is conceptualised in India, within four recent…

  20. Vulnerability to Violence of "Talibe" Children in Mauritania

    ERIC Educational Resources Information Center

    Ballet, Jerome; Bhukuth, Augendra; Hamzetta, Bilal

    2012-01-01

    "Talibe" children are children sent to Quranic schools (daaras), where they are completely dependent on a master, known as a marabout. This is a very common system of education in formerly French-speaking countries in West Africa. In the last 10 years or so, numerous cases of violence towards "talibe" children have been…

  1. Student Success: Approaches to Modeling Student Matriculation and Retention

    ERIC Educational Resources Information Center

    Lin, Jien-Jou

    2013-01-01

    Every year a group of graduates from high schools enter the engineering programs across this country with remarkable academic record. However, as reported in numerous studies, the number of students switching out of engineering majors continues to be an important issue. Previous studies have suggested various factors as predictors for student…

  2. The Don Bosco Way to Train Disadvantaged Youth. Discussion Paper No. 92.

    ERIC Educational Resources Information Center

    Mashek, R. W.

    Founded by Don Bosco in 1859 in Turin, Italy, the Salesian Society helps disadvantaged youth in over 100 countries, according to 1991 data. Salesians operate technical training institutes and run numerous informal shops and training courses within their schools, orphanages, street children shelters, and youth centers. The institutes are financed…

  3. Divided We Fall: The Federal Government Confronts the Digital Divide

    ERIC Educational Resources Information Center

    Jackson, Charmaine

    2003-01-01

    For several decades, education has assumed a vital role in this country's economic, social, and political development, catapulting less advantaged citizens into higher social classes and the political process. A testament to education's fundamental importance in our society are the numerous programs designed during the 1960s to eliminate the…

  4. Corruption Hierarchies in Higher Education in the Former Soviet Bloc

    ERIC Educational Resources Information Center

    Osipian, Ararat L.

    2009-01-01

    Corruption in higher education is known but not described theoretically. Decentralization and privatization of higher education and the increasing scale and scope of corruption in higher education in the former Soviet Bloc, as well as numerous other countries, urges better understanding of the problem within the context of socio-economic…

  5. The prevalence of early postpartum psychiatric morbidity in Dubai: a transcultural perspective.

    PubMed

    Abou-Saleh, M T; Ghubash, R

    1997-05-01

    There have been numerous studies of the prevalence of postpartum psychiatric illness and its putative risk factors in Western Europe and North America, but very few studies have been undertaken in developing countries, including the Arab world. A total of 95 women admitted to the New Dubai Hospital in Dubai, United Arab Emirates, for childbirth were studied. All subjects were assessed in the postpartum period using clinical and socio-cultural instruments, namely the Self-Reporting Questionnaire (SRQ) on day 2 and the Edinburgh Postnatal Depression Scale (EPDS) on day 7 after delivery. The prevalence of psychiatric morbidity was 24% according to the SRQ and 18% according to the EPDS. A number of psychosocial factors emerged as putative risk factors for postpartum psychiatric disturbance, including depressive illness. It is concluded that the prevalence of postpartum psychiatric morbidity and its risk factors in this Arab culture are similar to the results obtained in numerous previous studies conducted in industrialized countries. These findings have implications for the early detection and care of women at risk for postpartum psychiatric illness.

  6. Postpartum psychiatric illness in Arab culture: prevalence and psychosocial correlates.

    PubMed

    Ghubash, R; Abou-Saleh, M T

    1997-07-01

    There have been numerous studies of the prevalence of postpartum depression and its putative risk factors in Western Europe and North America, but very few studies in developing countries including the Arab world. Ninety-five women admitted to the New Dubai Hospital in Dubai, United Arab Emirates, for childbirth were studied. All subjects were assessed in the postpartum period using clinical and socio-cultural instruments: the Self Report Questionnaire (SRQ) at day 2, the Edinburgh Postnatal Depression Scale (EPDS) at day 7, and the Present State Examination (PSE) at week 8 +/- 2 and week 30 +/- 2 after delivery. The prevalence rate of psychiatric morbidity was 24.5% by the SRQ, 17.8% by the EPDS, and 15.8% by the PSE. A number of psychosocial factors emerged as putative risk factors for postpartum depression. The prevalence rates of postpartum psychiatric morbidity and its risk factors in this Arab culture are similar to the results obtained in numerous previous studies in industrialised countries. These findings have implications for the early detection and care of women at risk for postpartum depression.

  7. Evaluation of Immigrant Tuberculosis Screening in Industrialized Countries

    PubMed Central

    Pareek, Manish; Baussano, Iacopo; Abubakar, Ibrahim; Dye, Christopher

    2012-01-01

    In industrialized countries, tuberculosis (TB) cases are concentrated among immigrants and driven by reactivation of imported latent TB infection (LTBI). We examined mechanisms used to screen immigrants for TB and LTBI by sending an anonymous, 18-point questionnaire to 31 member countries of the Organisation for Economic Co-operation and Development. Twenty-nine (93.5%) of 31 responded; 25 (86.2%) screened immigrants for active TB. Fewer countries (16/29, 55.2%) screened for LTBI. Marked variations were observed in targeted populations for age (range <5 years of age to all age groups) and TB incidence in countries of origin of immigrants (>20 cases/100,000 population to >500 cases/100,000). LTBI screening was conducted in 11/16 countries by using the tuberculin skin test. Six countries used interferon-γ release assays, primarily to confirm positive tuberculin skin test results. Industrialized countries performed LTBI screening infrequently and policies varied widely. There is an urgent need to define the cost-effectiveness of LTBI screening strategies for immigrants. PMID:22931959

  8. Native Rodent Species Are Unlikely Sources of Infection for Leishmania (Viannia) braziliensis along the Transoceanic Highway in Madre de Dios, Peru

    PubMed Central

    Shender, Lisa A.; De Los Santos, Maxy; Montgomery, Joel M.; Conrad, Patricia A.; Ghersi, Bruno M.; Razuri, Hugo; Lescano, Andres G.; Mazet, Jonna A. K.

    2014-01-01

    An estimated 2.3 million disability-adjusted life years are lost globally from leishmaniasis. In Peru's Amazon region, the department of Madre de Dios (MDD) rises above the rest of the country in terms of the annual incidence rates of human leishmaniasis. Leishmania (Viannia) braziliensis is the species most frequently responsible for the form of disease that results in tissue destruction of the nose and mouth. However, essentially nothing is known regarding the reservoirs of this vector-borne, zoonotic parasite in MDD. Wild rodents have been suspected, or proven, to be reservoirs of several Leishmania spp. in various ecosystems and countries. Additionally, people who live or work in forested terrain, especially those who are not regionally local and whose immune systems are thus naïve to the parasite, are at most risk for contracting L. (V.) braziliensis. Hence, the objective of this study was to collect tissues from wild rodents captured at several study sites along the Amazonian segment of the newly constructed Transoceanic Highway and to use molecular laboratory techniques to analyze samples for the presence of Leishmania parasites. Liver tissues were tested via polymerase chain reaction from a total of 217 rodents; bone marrow and skin biopsies (ear and tail) were also tested from a subset of these same animals. The most numerous rodent species captured and tested were Oligoryzomys microtis (40.7%), Hylaeamys perenensis (15.7%), and Proechimys spp. (12%). All samples were negative for Leishmania, implying that although incidental infections may occur, these abundant rodent species are unlikely to serve as primary reservoirs of L. (V.) braziliensis along the Transoceanic Highway in MDD. Therefore, although these rodent species may persist and even thrive in moderately altered landscapes, we did not find any evidence to suggest they pose a risk for L. (V.) braziliensis transmission to human inhabitants in this highly prevalent region. PMID:25062033

  9. Native rodent species are unlikely sources of infection for Leishmania (Viannia) braziliensis along the Transoceanic Highway in Madre de Dios, Peru.

    PubMed

    Shender, Lisa A; De Los Santos, Maxy; Montgomery, Joel M; Conrad, Patricia A; Ghersi, Bruno M; Razuri, Hugo; Lescano, Andres G; Mazet, Jonna A K

    2014-01-01

    An estimated 2.3 million disability-adjusted life years are lost globally from leishmaniasis. In Peru's Amazon region, the department of Madre de Dios (MDD) rises above the rest of the country in terms of the annual incidence rates of human leishmaniasis. Leishmania (Viannia) braziliensis is the species most frequently responsible for the form of disease that results in tissue destruction of the nose and mouth. However, essentially nothing is known regarding the reservoirs of this vector-borne, zoonotic parasite in MDD. Wild rodents have been suspected, or proven, to be reservoirs of several Leishmania spp. in various ecosystems and countries. Additionally, people who live or work in forested terrain, especially those who are not regionally local and whose immune systems are thus naïve to the parasite, are at most risk for contracting L. (V.) braziliensis. Hence, the objective of this study was to collect tissues from wild rodents captured at several study sites along the Amazonian segment of the newly constructed Transoceanic Highway and to use molecular laboratory techniques to analyze samples for the presence of Leishmania parasites. Liver tissues were tested via polymerase chain reaction from a total of 217 rodents; bone marrow and skin biopsies (ear and tail) were also tested from a subset of these same animals. The most numerous rodent species captured and tested were Oligoryzomys microtis (40.7%), Hylaeamys perenensis (15.7%), and Proechimys spp. (12%). All samples were negative for Leishmania, implying that although incidental infections may occur, these abundant rodent species are unlikely to serve as primary reservoirs of L. (V.) braziliensis along the Transoceanic Highway in MDD. Therefore, although these rodent species may persist and even thrive in moderately altered landscapes, we did not find any evidence to suggest they pose a risk for L. (V.) braziliensis transmission to human inhabitants in this highly prevalent region.

  10. The end of donor anonymity: how genetic testing is likely to drive anonymous gamete donation out of business.

    PubMed

    Harper, Joyce C; Kennett, Debbie; Reisel, Dan

    2016-06-01

    Thousands of people worldwide have been conceived using donor gametes, but not all parents tell their children of their origin. Several countries now allow donor-conceived offspring to potentially know their genetic parent if they are informed of their donor-conceived status. At the same time, personal genetic testing is a rapidly expanding field. Over 3 million people have already used direct-to-consumer genetic testing to find information about their ancestry, and many are participating in international genetic genealogy databases that will match them with relatives. The increased prevalence of these technologies poses numerous challenges to the current practice of gamete donation. (i) Whether they are donating in a country that practices anonymous donation or not, donors should be informed that their anonymity is not guaranteed, as they may be traced if their DNA, or that of a relative, is added to a database. (ii) Donor-conceived adults who have not been informed of their status may find out that they are donor-conceived. (iii) Parents using donor conception need to be fully informed that their children's DNA will identify that they are not the biological parents and they should be encouraged to disclose the use of donor gametes to their children. Together, these concerns make urgent a wide-ranging societal conversation about how to best safeguard and promote the interests of donor-conceived offspring and protect the rights of donors. Specifically, there is a need to ensure that new genetic information is communicated in a way that promotes both the safety and the privacy rights of offspring and donors alike. All parties concerned must be aware that, in 2016, donor anonymity does not exist. © The Author 2016. Published by Oxford University Press on behalf of the European Society of Human Reproduction and Embryology. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  11. Developing a Numerical Ability Test for Students of Education in Jordan: An Application of Item Response Theory

    ERIC Educational Resources Information Center

    Abed, Eman Rasmi; Al-Absi, Mohammad Mustafa; Abu shindi, Yousef Abdelqader

    2016-01-01

    The purpose of the present study is developing a test to measure the numerical ability for students of education. The sample of the study consisted of (504) students from 8 universities in Jordan. The final draft of the test contains 45 items distributed among 5 dimensions. The results revealed that acceptable psychometric properties of the test;…

  12. HIV testing and counselling for migrant populations living in high-income countries: a systematic review

    PubMed Central

    Monge, Susana; Azcoaga, Amaya; Rio, Isabel; Hernando, Victoria; Gonzalez, Cristina; Alejos, Belen; Caro, Ana Maria; Perez-Cachafeiro, Santiago; Ramirez-Rubio, Oriana; Bolumar, Francisco; Noori, Teymur; Del Amo, Julia

    2013-01-01

    Background: The barriers to HIV testing and counselling that migrants encounter can jeopardize proactive HIV testing that relies on the fact that HIV testing must be linked to care. We analyse available evidence on HIV testing and counselling strategies targeting migrants and ethnic minorities in high-income countries. Methods: Systematic literature review of the five main databases of articles in English from Europe, North America and Australia between 2005 and 2009. Results: Of 1034 abstracts, 37 articles were selected. Migrants, mainly from HIV-endemic countries, are at risk of HIV infection and its consequences. The HIV prevalence among migrants is higher than the general population’s, and migrants have higher frequency of delayed HIV diagnosis. For migrants from countries with low HIV prevalence and for ethnic minorities, socio-economic vulnerability puts them at risk of acquiring HIV. Migrants have specific legal and administrative impediments to accessing HIV testing—in some countries, undocumented migrants are not entitled to health care—as well as cultural and linguistic barriers, racism and xenophobia. Migrants and ethnic minorities fear stigma from their communities, yet community acceptance is key for well-being. Conclusions: Migrants and ethnic minorities should be offered HIV testing, but the barriers highlighted in this review may deter programs from achieving the final goal, which is linking migrants and ethnic minorities to HIV clinical care under the public health perspective. PMID:23002238

  13. Cross-cultural equivalence of the patient- and parent-reported quality of life in short stature youth (QoLISSY) questionnaire.

    PubMed

    Bullinger, Monika; Quitmann, Julia; Silva, Neuza; Rohenkohl, Anja; Chaplin, John E; DeBusk, Kendra; Mimoun, Emmanuelle; Feigerlova, Eva; Herdman, Michael; Sanz, Dolores; Wollmann, Hartmut; Pleil, Andreas; Power, Michael

    2014-01-01

    Testing cross-cultural equivalence of patient-reported outcomes requires sufficiently large samples per country, which is difficult to achieve in rare endocrine paediatric conditions. We describe a novel approach to cross-cultural testing of the Quality of Life in Short Stature Youth (QoLISSY) questionnaire in five countries by sequentially taking one country out (TOCO) from the total sample and iteratively comparing the resulting psychometric performance. Development of the QoLISSY proceeded from focus group discussions through pilot testing to field testing in 268 short-statured patients and their parents. To explore cross-cultural equivalence, the iterative TOCO technique was used to examine and compare the validity, reliability, and convergence of patient and parent responses on QoLISSY in the field test dataset, and to predict QoLISSY scores from clinical, socio-demographic and psychosocial variables. Validity and reliability indicators were satisfactory for each sample after iteratively omitting one country. Comparisons with the total sample revealed cross-cultural equivalence in internal consistency and construct validity for patients and parents, high inter-rater agreement and a substantial proportion of QoLISSY variance explained by predictors. The TOCO technique is a powerful method to overcome problems of country-specific testing of patient-reported outcome instruments. It provides an empirical support to QoLISSY's cross-cultural equivalence and is recommended for future research.

  14. Agricultural Policies Exacerbate Honeybee Pollination Service Supply-Demand Mismatches Across Europe

    PubMed Central

    Breeze, Tom D.; Vaissière, Bernard E.; Bommarco, Riccardo; Petanidou, Theodora; Seraphides, Nicos; Kozák, Lajos; Scheper, Jeroen; Biesmeijer, Jacobus C.; Kleijn, David; Gyldenkærne, Steen; Moretti, Marco; Holzschuh, Andrea; Steffan-Dewenter, Ingolf; Stout, Jane C.; Pärtel, Meelis; Zobel, Martin; Potts, Simon G.

    2014-01-01

    Declines in insect pollinators across Europe have raised concerns about the supply of pollination services to agriculture. Simultaneously, EU agricultural and biofuel policies have encouraged substantial growth in the cultivated area of insect pollinated crops across the continent. Using data from 41 European countries, this study demonstrates that the recommended number of honeybees required to provide crop pollination across Europe has risen 4.9 times as fast as honeybee stocks between 2005 and 2010. Consequently, honeybee stocks were insufficient to supply >90% of demands in 22 countries studied. These findings raise concerns about the capacity of many countries to cope with major losses of wild pollinators and highlight numerous critical gaps in current understanding of pollination service supplies and demands, pointing to a pressing need for further research into this issue. PMID:24421873

  15. Overview of Heat Addition and Efficiency Predictions for an Advanced Stirling Convertor

    NASA Technical Reports Server (NTRS)

    Wilson, Scott D.; Reid, Terry V.; Schifer, Nicholas A.; Briggs, Maxwell H.

    2012-01-01

    The U.S. Department of Energy (DOE) and Lockheed Martin Space Systems Company (LMSSC) have been developing the Advanced Stirling Radioisotope Generator (ASRG) for use as a power system for space science missions. This generator would use two high-efficiency Advanced Stirling Convertors (ASCs), developed by Sunpower Inc. and NASA Glenn Research Center (GRC). The ASCs convert thermal energy from a radioisotope heat source into electricity. As part of ground testing of these ASCs, different operating conditions are used to simulate expected mission conditions. These conditions require achieving a particular operating frequency, hot end and cold end temperatures, and specified electrical power output for a given net heat input. Microporous bulk insulation is used in the ground support test hardware to minimize the loss of thermal energy from the electric heat source to the environment. The insulation package is characterized before operation to predict how much heat will be absorbed by the convertor and how much will be lost to the environment during operation. In an effort to validate these predictions, numerous tasks have been performed, which provided a more accurate value for net heat input into the ASCs. This test and modeling effort included: (a) making thermophysical property measurements of test setup materials to provide inputs to the numerical models, (b) acquiring additional test data that was collected during convertor tests to provide numerical models with temperature profiles of the test setup via thermocouple and infrared measurements, (c) using multidimensional numerical models (computational fluid dynamics code) to predict net heat input of an operating convertor, and (d) using validation test hardware to provide direct comparison of numerical results and validate the multidimensional numerical models used to predict convertor net heat input. This effort produced high fidelity ASC net heat input predictions, which were successfully validated using specially designed test hardware enabling measurement of heat transferred through a simulated Stirling cycle. The overall effort and results are discussed.

  16. Cognitive screening tools for identification of dementia in illiterate and low-educated older adults, a systematic review and meta-analysis.

    PubMed

    Paddick, Stella-Maria; Gray, William K; McGuire, Jackie; Richardson, Jenny; Dotchin, Catherine; Walker, Richard W

    2017-06-01

    The majority of older adults with dementia live in low- and middle-income countries (LMICs). Illiteracy and low educational background are common in older LMIC populations, particularly in rural areas, and cognitive screening tools developed for this setting must reflect this. This study aimed to review published validation studies of cognitive screening tools for dementia in low-literacy settings in order to determine the most appropriate tools for use. A systematic search of major databases was conducted according to PRISMA guidelines. Validation studies of brief cognitive screening tests including illiterate participants or those with elementary education were eligible. Studies were quality assessed using the QUADAS-2 tool. Good or fair quality studies were included in a bivariate random-effects meta-analysis and a hierarchical summary receiver operating characteristic (HSROC) curve constructed. Forty-five eligible studies were quality assessed. A significant proportion utilized a case-control design, resulting in spectrum bias. The area under the ROC (AUROC) curve was 0.937 for community/low prevalence studies, 0.881 for clinic based/higher prevalence studies, and 0.869 for illiterate populations. For the Mini-Mental State Examination (MMSE) (and adaptations), the AUROC curve was 0.853. Numerous tools for assessment of cognitive impairment in low-literacy settings have been developed, and tools developed for use in high-income countries have also been validated in low-literacy settings. Most tools have been inadequately validated, with only MMSE, cognitive abilities screening instrument (CASI), Eurotest, and Fototest having more than one published good or fair quality study in an illiterate or low-literate setting. At present no screening test can be recommended.

  17. The Use of Standardized Tests in Secondary Schools in Four European Countries.

    ERIC Educational Resources Information Center

    Postlethwaite, T. Neville

    The use of standardized testing in secondary schools (with students between 10 and 19 years old) is described for four European countries: (1) England; (2) West Germany; (3) the Netherlands; and (4) Sweden. In the decentralized English system, several published standardized tests are available; they are used less at the secondary level than in…

  18. Numerical Modeling of Active Flow Control in a Boundary Layer Ingesting Offset Inlet

    NASA Technical Reports Server (NTRS)

    Allan, Brian G.; Owens, Lewis R.; Berrier, Bobby L.

    2004-01-01

    This investigation evaluates the numerical prediction of flow distortion and pressure recovery for a boundary layer ingesting offset inlet with active flow control devices. The numerical simulations are computed using a Reynolds averaged Navier-Stokes code developed at NASA. The numerical results are validated by comparison to experimental wind tunnel tests conducted at NASA Langley Research Center at both low and high Mach numbers. Baseline comparisons showed good agreement between numerical and experimental results. Numerical simulations for the inlet with passive and active flow control also showed good agreement at low Mach numbers where experimental data has already been acquired. Numerical simulations of the inlet at high Mach numbers with flow control jets showed an improvement of the flow distortion. Studies on the location of the jet actuators, for the high Mach number case, were conducted to provide guidance for the design of a future experimental wind tunnel test.

  19. Guiding healthier food choice: systematic comparison of four front-of-pack labelling systems and their effect on judgements of product healthiness.

    PubMed

    Hodgkins, Charo E; Raats, Monique M; Fife-Schaw, Chris; Peacock, Matthew; Gröppel-Klein, Andrea; Koenigstorfer, Joerg; Wasowicz, Grazyna; Stysko-Kunkowska, Malgorzata; Gulcan, Yaprak; Kustepeli, Yesim; Gibbs, Michelle; Shepherd, Richard; Grunert, Klaus G

    2015-05-28

    Different front-of-pack (FOP) labelling systems have been developed in Europe by industry and organisations concerned with health promotion. A study (n 2068) was performed to establish the extent to which inclusion of the most prevalent FOP systems--guideline daily amounts (GDA), traffic lights (TL), GDA+TL hybrid (HYB) and health logos (HL)--impact consumer perceptions of healthiness over and above the provision of a FOP basic label (BL) containing numerical nutritional information alone. The design included within- and between-subjects factors. The within-subjects factors were: food (pizzas, yogurts and biscuits), healthiness of the food (high health, medium health and low health) and the repeated measurements under BL and test FOP label conditions. The between-subjects factors were: the system (GDA, TL, GDA+TL hybrid, HL), portion size (typical portion size and a 50% reduction of a typical portion) and country (the UK, Germany, Poland and Turkey). Although the FOP systems tested did result in small improvements for objective understanding under some conditions, there was little difference between the provision of an FOP label containing basic numerical nutritional information alone or between the various systems. Thus, any structured and legible presentation of key nutrient and energy information on the FOP label is sufficient to enable consumers to detect a healthier alternative within a food category when provided with foods that have distinctly different levels of healthiness. Future research should focus on developing greater understanding of the psychological and contextual factors that impact motivation and the opportunity to use the various FOP systems in real-world shopping settings.

  20. Legislation on direct-to-consumer genetic testing in seven European countries.

    PubMed

    Borry, Pascal; van Hellemondt, Rachel E; Sprumont, Dominique; Jales, Camilla Fittipaldi Duarte; Rial-Sebbag, Emmanuelle; Spranger, Tade Matthias; Curren, Liam; Kaye, Jane; Nys, Herman; Howard, Heidi

    2012-07-01

    An increasing number of private companies are now offering direct-to-consumer (DTC) genetic testing services. Although a lot of attention has been devoted to the regulatory framework of DTC genetic testing services in the USA, only limited information about the regulatory framework in Europe is available. We will report on the situation with regard to the national legislation on DTC genetic testing in seven European countries (Belgium, the Netherlands, Switzerland, Portugal, France, Germany, the United Kingdom). The paper will address whether these countries have legislation that specifically address the issue of DTC genetic testing or have relevant laws that is pertinent to the regulatory control of these services in their countries. The findings show that France, Germany, Portugal and Switzerland have specific legislation that defines that genetic tests can only be carried out by a medical doctor after the provision of sufficient information concerning the nature, meaning and consequences of the genetic test and after the consent of the person concerned. In the Netherlands, some DTC genetic tests could fall under legislation that provides the Minister the right to refuse to provide a license to operate if a test is scientifically unsound, not in accordance with the professional medical practice standards or if the expected benefit is not in balance with the (potential) health risks. Belgium and the United Kingdom allow the provision of DTC genetic tests.

  1. Legislation on direct-to-consumer genetic testing in seven European countries

    PubMed Central

    Borry, Pascal; van Hellemondt, Rachel E; Sprumont, Dominique; Jales, Camilla Fittipaldi Duarte; Rial-Sebbag, Emmanuelle; Spranger, Tade Matthias; Curren, Liam; Kaye, Jane; Nys, Herman; Howard, Heidi

    2012-01-01

    An increasing number of private companies are now offering direct-to-consumer (DTC) genetic testing services. Although a lot of attention has been devoted to the regulatory framework of DTC genetic testing services in the USA, only limited information about the regulatory framework in Europe is available. We will report on the situation with regard to the national legislation on DTC genetic testing in seven European countries (Belgium, the Netherlands, Switzerland, Portugal, France, Germany, the United Kingdom). The paper will address whether these countries have legislation that specifically address the issue of DTC genetic testing or have relevant laws that is pertinent to the regulatory control of these services in their countries. The findings show that France, Germany, Portugal and Switzerland have specific legislation that defines that genetic tests can only be carried out by a medical doctor after the provision of sufficient information concerning the nature, meaning and consequences of the genetic test and after the consent of the person concerned. In the Netherlands, some DTC genetic tests could fall under legislation that provides the Minister the right to refuse to provide a license to operate if a test is scientifically unsound, not in accordance with the professional medical practice standards or if the expected benefit is not in balance with the (potential) health risks. Belgium and the United Kingdom allow the provision of DTC genetic tests. PMID:22274578

  2. Statistical considerations for harmonization of the global multicenter study on reference values.

    PubMed

    Ichihara, Kiyoshi

    2014-05-15

    The global multicenter study on reference values coordinated by the Committee on Reference Intervals and Decision Limits (C-RIDL) of the IFCC was launched in December 2011, targeting 45 commonly tested analytes with the following objectives: 1) to derive reference intervals (RIs) country by country using a common protocol, and 2) to explore regionality/ethnicity of reference values by aligning test results among the countries. To achieve these objectives, it is crucial to harmonize 1) the protocol for recruitment and sampling, 2) statistical procedures for deriving the RI, and 3) test results through measurement of a panel of sera in common. For harmonized recruitment, very lenient inclusion/exclusion criteria were adopted in view of differences in interpretation of what constitutes healthiness by different cultures and investigators. This policy may require secondary exclusion of individuals according to the standard of each country at the time of deriving RIs. An iterative optimization procedure, called the latent abnormal values exclusion (LAVE) method, can be applied to automate the process of refining the choice of reference individuals. For global comparison of reference values, test results must be harmonized, based on the among-country, pair-wise linear relationships of test values for the panel. Traceability of reference values can be ensured based on values assigned indirectly to the panel through collaborative measurement of certified reference materials. The validity of the adopted strategies is discussed in this article, based on interim results obtained to date from five countries. Special considerations are made for dissociation of RIs by parametric and nonparametric methods and between-country difference in the effect of body mass index on reference values. Copyright © 2014 Elsevier B.V. All rights reserved.

  3. Intentional and automatic numerical processing as predictors of mathematical abilities in primary school children

    PubMed Central

    Pina, Violeta; Castillo, Alejandro; Cohen Kadosh, Roi; Fuentes, Luis J.

    2015-01-01

    Previous studies have suggested that numerical processing relates to mathematical performance, but it seems that such relationship is more evident for intentional than for automatic numerical processing. In the present study we assessed the relationship between the two types of numerical processing and specific mathematical abilities in a sample of 109 children in grades 1–6. Participants were tested in an ample range of mathematical tests and also performed both a numerical and a size comparison task. The results showed that numerical processing related to mathematical performance only when inhibitory control was involved in the comparison tasks. Concretely, we found that intentional numerical processing, as indexed by the numerical distance effect in the numerical comparison task, was related to mathematical reasoning skills only when the task-irrelevant dimension (the physical size) was incongruent; whereas automatic numerical processing, indexed by the congruency effect in the size comparison task, was related to mathematical calculation skills only when digits were separated by small distance. The observed double dissociation highlights the relevance of both intentional and automatic numerical processing in mathematical skills, but when inhibitory control is also involved. PMID:25873909

  4. Lessons Learned From Option B+ in the Evolution Toward "Test and Start" From Malawi, Cameroon, and the United Republic of Tanzania.

    PubMed

    Kalua, Thokozani; Tippett Barr, Beth A; van Oosterhout, Joep J; Mbori-Ngacha, Dorothy; Schouten, Erik J; Gupta, Sundeep; Sande, Amakobe; Zomba, Gerald; Tweya, Hannock; Lungu, Edgar; Kajoka, Deborah; Tih, Pius; Jahn, Andreas

    2017-05-01

    The acceleration of prevention of mother-to-child transmission (PMTCT) activities, coupled with the rollout of 2010 World Health Organization (WHO) guidelines, led to important discussions and innovations at global and country levels. One paradigm-shifting innovation was Option B+ in Malawi. It was later included in WHO guidelines and eventually adopted by all 22 Global Plan priority countries. This article presents Malawi's experience with designing and implementing Option B+ and provides complementary narratives from Cameroon and Tanzania. Malawi's HIV program started in 2002, but by 2009, the PMTCT program was lagging far behind the antiretroviral therapy (ART) program because of numerous health system challenges. When WHO recommended Option A and Option B for PMTCT in 2010, it was clear that Malawi's HIV program would not be able to successfully implement either option without increasing existing barriers to PMTCT services and potentially decreasing women's access to care. Subsequent stakeholder discussions led to the development of Option B+. Operationalizing Option B+ required several critical considerations, including the complete integration of ART and PMTCT programs, systematic reduction of barriers to facilitate doubling the number of ART sites in less than a year, building consensus with stakeholders, and securing additional resources for the new program. During the planning and implementation process, several lessons were learned which are considerations for countries transitioning to "treat-all": Comprehensive change requires effective government leadership and coordination; national clinical guidelines must accommodate health system limitations; ART services and commodities should be decentralized within facilities; the general public should be well informed about major changes in the national HIV program; and patients should be educated on clinic processes to improve program monitoring.

  5. Can self-testing increase HIV testing among men who have sex with men: A systematic review and meta-analysis.

    PubMed

    Zhang, Ci; Li, Xianhong; Brecht, Mary-Lynn; Koniak-Griffin, Deborah

    2017-01-01

    Globally, four out of ten individuals living with HIV have not been tested for HIV. Testing is especially important for men who have sex with men (MSM), among whom an increasing HIV epidemic has been identified in many regions of the world. As a supplement to site-based HIV testing services, HIV self-testing (HIVST) provides a promising approach to promote HIV testing. However, evidence is scattered and not well-summarized on the effect of HIVST to improve HIV testing behaviors, especially for MSM. Seven databases (PubMed, Web of Science, Cochrane Library, PsycINFO, CINAHL Plus, WanFang, and China National Knowledge Internet) and conference abstracts from six HIV/sexually transmitted infections conferences were searched from January 2000-April 2017. Of 1,694 records retrieved, 23 studies were identified, 9 conducted in resource-limited countries and 14 in high-income countries. The pooled results showed that HIVST increased HIV test frequency for MSM by one additional test in a 6-month period (mean difference = 0.88 [95% CI 0.52-1.24]). The pooled proportion of first-time testers among those who took HIVST was 18.7% (95% CI: 9.9-32.4) globally, with a rate 3.32 times higher in resource-limited country settings (32.9% [95% CI: 21.3-47.6]) than in high-income countries (9.9% [95% CI: 7.4-13.8]). The pooled proportions included non-recent testers, 32.9% (95% CI: 28.1-38.3); ever or currently married MSM, 16.7% (95% CI: 14.5-19.4); and HIV positive men, 3.8% (95% CI: 2.0-5.7) globally; 6.5% [95% CI: 0.38-12.3] in resource-limited country settings; and 2.9% [95% CI: 2.0-5.0] in high-income countries). The rates reported for linkage to care ranged from 31.3% to 100%. HIVST could increase HIV testing frequency and potentially have capacity equivalent to that of site-based HIV testing services to reach first-time, delayed, married, and HIV-infected testers among MSM and link them to medical care. However, more rigorous study designs are needed to explore the specific self-testing approach (oral-fluid based or finger-prick based) on improving HIV testing for MSM in different social and economic settings.

  6. Harm reduction and viral hepatitis C in European prisons: a cross-sectional survey of 25 countries.

    PubMed

    Bielen, Rob; Stumo, Samya R; Halford, Rachel; Werling, Klára; Reic, Tatjana; Stöver, Heino; Robaeys, Geert; Lazarus, Jeffrey V

    2018-05-11

    Current estimates suggest that 15% of all prisoners worldwide are chronically infected with the hepatitis C virus (HCV), and this number is even higher in regions with high rates of injecting drug use. Although harm reduction services such as opioid substitution therapy (OST) and needle and syringe programs (NSPs) are effective in preventing the further spread of HCV and HIV, the extent to which these are available in prisons varies significantly across countries. The Hep-CORE study surveyed liver patient groups from 25 European countries in 2016 and mid-2017 on national policies related to harm reduction, testing/screening, and treatment for HCV in prison settings. Results from the cross-sectional survey were compared to the data from available reports and the peer-reviewed literature to determine the overall degree to which European countries implement evidence-based HCV recommendations in prison settings. Patient groups in nine countries (36%) identified prisoners as a high-risk population target for HCV testing/screening. Twenty-one countries (84%) provide HCV treatment in prisons. However, the extent of coverage of these treatment programs varies widely. Two countries (8%) have NSPs officially available in prisons in all parts of the country. Eleven countries (44%) provide OST in prisons in all parts of the country without additional requirements. Despite the existence of evidence-based recommendations, infectious disease prevention measures such as harm reduction programs are inadequate in European prison settings. Harm reduction, HCV testing/screening, and treatment should be scaled up in prison settings in order to progress towards eliminating HCV as a public health threat.

  7. Potential utilization of biodiesel as alternative fuel for compression ignition engine in Malaysia

    NASA Astrophysics Data System (ADS)

    Wahab, M. A.; Ma'arof, M. I. N.; Ahmad, I. N.; Husain, H.

    2017-10-01

    Biodiesel is a type of fuel which is derived from various sources of vegetable plants and waste fuels. Today, numerous biodiesels have been engineered to be at par or even better in term of performance in comparison to pure diesel. Therefore, biodiesel has shown a promising sign as one of the best candidate in overcoming total dependency on pure diesel. This paper gives review on various tests and experiments conducted on biodiesel in order to highlight the potentials given by this particular fuel. In addition, providing the supporting evidences to further endorse for a mass usage of biodiesel in Malaysia - simultaneously, driving the country to become a potential global biodiesel producer in the near future. The reviewed studies were obtained mainly via indexed journals and online libraries. Conclusively, every test and study for every blend of biodiesel had shown consistent positive results in regards to performance and in overcoming emission related issues. Thus, providing the evidence that biodiesel is highly reliable. Malaysia as a semi-agricultural nation could take the advantage in becoming one of the leading global biodiesel producers. Nevertheless, this will requires total cooperation of every concerned government bodies and authorities.

  8. Application of Paste Backfill in Underground Coal Fires

    NASA Astrophysics Data System (ADS)

    Masniyom, M.; Drebenstedt, C.

    2009-04-01

    Coal fires are known from different coalfields worldwide. China, India, USA, Australia, Indonesia and South Africa are the main countries affected by coal fires. The fires is thermally intensive and cause numerous sinkholes, large-scale subsidence, air pollution, global warming, loss of mining productivity and increasing safety risk. The Wuda Inner Mongolia coalfield has been selected as a possible test area for paste backfill. The traditional methods, executed by fire fighting teams, by covering the coalfire areas with soil, blasting burning coal outcrops and injecting water in the subsurface fire pockets are continuously improved and extended. Initiatives to introduce modern techniques, such as backfill placement at fracture and borehole, to cool down the burning coal and cut off the air supply. This study is to investigate backfill materials and techniques suited for underground coal fires. Laboratory tests were carried out on physical, chemical and mechanical properties of different backfill materials and mixtures thereof. Special attention was paid to materials generated as by-products and other cheaply available materials e.g. fly ash from power plants. There is a good chance that one of the different material mixtures investigated can be used as a technically and economically viable backfill for underground coal fires.

  9. Thermoviscoelastic characterization and prediction of Kevlar/epoxy composite laminates

    NASA Technical Reports Server (NTRS)

    Gramoll, K. C.; Dillard, D. A.; Brinson, H. F.

    1990-01-01

    The thermoviscoelastic characterization of Kevlar 49/Fiberite 7714A epoxy composite lamina and the development of a numerical procedure to predict the viscoelastic response of any general laminate constructed from the same material were studied. The four orthotropic material properties, S sub 11, S sub 12, S sub 22, and S sub 66, were characterized by 20 minute static creep tests on unidirectional (0) sub 8, (10) sub 8, and (90) sub 16 lamina specimens. The Time-Temperature Superposition-Principle (TTSP) was used successfully to accelerate the characterization process. A nonlinear constitutive model was developed to describe the stress dependent viscoelastic response for each of the material properties. A numerical procedure to predict long term laminate properties from lamina properties (obtained experimentally) was developed. Numerical instabilities and time constraints associated with viscoelastic numerical techniques were discussed and solved. The numerical procedure was incorporated into a user friendly microcomputer program called Viscoelastic Composite Analysis Program (VCAP), which is available for IBM PC type computers. The program was designed for ease of use. The final phase involved testing actual laminates constructed from the characterized material, Kevlar/epoxy, at various temperatures and load level for 4 to 5 weeks. These results were compared with the VCAP program predictions to verify the testing procedure and to check the numerical procedure used in the program. The actual tests and predictions agreed for all test cases which included 1, 2, 3, and 4 fiber direction laminates.

  10. Adipose tissue as an endocrine organ.

    PubMed

    McGown, Christine; Birerdinc, Aybike; Younossi, Zobair M

    2014-02-01

    Obesity is one of the most important health challenges faced by developed countries and is increasingly affecting adolescents and children. Obesity is also a considerable risk factor for the development of numerous other chronic diseases, such as insulin resistance, type 2 diabetes, heart disease and nonalcoholic fatty liver disease. The epidemic proportions of obesity and its numerous comorbidities are bringing into focus the highly complex and metabolically active adipose tissue. Adipose tissue is increasingly being considered as a functional endocrine organ. This article discusses the endocrine effects of adipose tissue during obesity and the systemic impact of this signaling. Copyright © 2014 Elsevier Inc. All rights reserved.

  11. 76 FR 61282 - Defense Federal Acquisition Regulation Supplement; Definition of “Qualifying Country End Product...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-04

    ... Federal Acquisition Regulation Supplement; Definition of ``Qualifying Country End Product'' (DFARS Case... Supplement (DFARS) to revise the definition of ``qualifying country end product.'' This final rule eliminates the component test for qualifying country end products that are commercially available off-the-shelf...

  12. Numerical and analytical modeling of the end-loaded split (ELS) test specimens made of multi-directional coupled composite laminates

    NASA Astrophysics Data System (ADS)

    Samborski, Sylwester; Valvo, Paolo S.

    2018-01-01

    The paper deals with the numerical and analytical modelling of the end-loaded split test for multi-directional laminates affected by the typical elastic couplings. Numerical analysis of three-dimensional finite element models was performed with the Abaqus software exploiting the virtual crack closure technique (VCCT). The results show possible asymmetries in the widthwise deflections of the specimen, as well as in the strain energy release rate (SERR) distributions along the delamination front. Analytical modelling based on a beam-theory approach was also conducted in simpler cases, where only bending-extension coupling is present, but no out-of-plane effects. The analytical results matched the numerical ones, thus demonstrating that the analytical models are feasible for test design and experimental data reduction.

  13. Factorial validity and measurement equivalence of the Client Assessment of Treatment Scale for psychiatric inpatient care - a study in three European countries.

    PubMed

    Richardson, Michelle; Katsakou, Christina; Torres-González, Francisco; Onchev, George; Kallert, Thomas; Priebe, Stefan

    2011-06-30

    Patients' views of inpatient care need to be assessed for research and routine evaluation. For this a valid instrument is required. The Client Assessment of Treatment Scale (CAT) has been used in large scale international studies, but its psychometric properties have not been well established. The structural validity of the CAT was tested among involuntary inpatients with psychosis. Data from locations in three separate European countries (England, Spain and Bulgaria) were collected. The factorial validity was initially tested using single sample confirmatory factor analyses in each country. Subsequent multi-sample analyses were used to test for invariance of the factor loadings, and factor variances across the countries. Results provide good initial support for the factorial validity and invariance of the CAT scores. Future research is needed to cross-validate these findings and to generalise them to other countries, treatment settings, and patient populations. Copyright © 2011 Elsevier Ltd. All rights reserved.

  14. Alternative method of highway traffic safety analysis for developing countries using delphi technique and Bayesian network.

    PubMed

    Mbakwe, Anthony C; Saka, Anthony A; Choi, Keechoo; Lee, Young-Jae

    2016-08-01

    Highway traffic accidents all over the world result in more than 1.3 million fatalities annually. An alarming number of these fatalities occurs in developing countries. There are many risk factors that are associated with frequent accidents, heavy loss of lives, and property damage in developing countries. Unfortunately, poor record keeping practices are very difficult obstacle to overcome in striving to obtain a near accurate casualty and safety data. In light of the fact that there are numerous accident causes, any attempts to curb the escalating death and injury rates in developing countries must include the identification of the primary accident causes. This paper, therefore, seeks to show that the Delphi Technique is a suitable alternative method that can be exploited in generating highway traffic accident data through which the major accident causes can be identified. In order to authenticate the technique used, Korea, a country that underwent similar problems when it was in its early stages of development in addition to the availability of excellent highway safety records in its database, is chosen and utilized for this purpose. Validation of the methodology confirms the technique is suitable for application in developing countries. Furthermore, the Delphi Technique, in combination with the Bayesian Network Model, is utilized in modeling highway traffic accidents and forecasting accident rates in the countries of research. Copyright © 2016 Elsevier Ltd. All rights reserved.

  15. Increasing women's access to skilled pregnancy care to reduce maternal and perinatal mortality in rural Edo State, Nigeria: a randomized controlled trial.

    PubMed

    Yaya, Sanni; Okonofua, Friday; Ntoimo, Lorretta; Kadio, Bernard; Deuboue, Rodrigue; Imongan, Wilson; Balami, Wapada

    2018-01-01

    Nigeria presently has the second highest absolute number of maternal deaths and perinatal deaths (stillbirth and neonatal deaths) in the world. The country accounts for up to 14% of global maternal deaths and is second only to India in the number of women who die during childbirth. Although all parts of the country are worsened by these staggering statistics, several lines of evidence show that most maternal, and perinatal deaths occur in the north-east and north-west geo-political zones where women have limited access to evidence-based maternal and neonatal health services. The proposed project intends to identify the demand and supply factors that prevent women from using PHCs for maternal and early new-born care in Nigeria, and to test innovative and community relevant interventions for improving women's access to PHC services, and thus, ultimately, to prevent maternal and perinatal deaths. An open-labelled, randomized controlled trial will is carried out in two local government areas selected based on three criteria (i) maternal mortality rates (ii) PHC utilization rates and (iii) and geographic localization. The study will be conducted over 54-months in six communities, with PHCs in six communities of similar status serving as control sites. Surveys about quality of care and maternal health services utilization will be carried out at baseline, at midterm and at end of the project to test the effectiveness of the intervention, alongside conventional epidemiological measures of maternal and perinatal mortality. Ethical approval for the study has been granted (reference no. NHREC/01/01/2007). The findings will be published in compliance with reporting guidelines for randomized controlled trials. The current Federal Government in Nigeria has identified PHC as its main strategy for increasing access to health in Nigeria. However, despite numerous efforts, there are persisting concerns that there is currently no scientific evidence on which to base the improvement of PHCs. The results of this study will identify barriers in the use of PHCs and will provide scientific evidence for effective and innovative interventions for improving PHCs that can be rolled out throughout the country. Clinical Trials.gov NCT02643953.

  16. The importance of Evolutionary Medicine in developing countries: A case for Pakistan's medical schools.

    PubMed

    Enam, Syed Faaiz; Hashmi, Shumaila

    2018-01-01

    Evolutionary Medicine (EM) is a fundamental science exploring why our bodies are plagued with disease and hindered by limitations. EM views the body as an assortment of benefits, mistakes, and compromises molded over millennia. It highlights the role of evolution in numerous diseases encountered in community and family medicine clinics of developing countries. It enables us to ask informed questions and develop novel responses to global health problems. An understanding of the field is thus crucial for budding doctors, but its study is currently limited to a handful of medical schools in high-income countries. For the developing world, Pakistan's medical schools may be excellent starting posts as the country is beset with communicable and non-communicable diseases that are shaped by evolution. Remarkably, Pakistani medical students are open to studying and incorporating EM into their training. Understanding the principles of EM could empower them to tackle growing health problems in the country. Additionally, some difficulties that western medical schools face in integrating EM into their curriculum may not be a hindrance in Pakistan. We propose solutions for the remaining challenges, including obstinate religious sentiments. Herein, we make the case that incorporating EM is particularly important in developing countries such as Pakistan and that it is achievable in its medical student body.

  17. The importance of Evolutionary Medicine in developing countries

    PubMed Central

    Hashmi, Shumaila

    2018-01-01

    Abstract Evolutionary Medicine (EM) is a fundamental science exploring why our bodies are plagued with disease and hindered by limitations. EM views the body as an assortment of benefits, mistakes, and compromises molded over millennia. It highlights the role of evolution in numerous diseases encountered in community and family medicine clinics of developing countries. It enables us to ask informed questions and develop novel responses to global health problems. An understanding of the field is thus crucial for budding doctors, but its study is currently limited to a handful of medical schools in high-income countries. For the developing world, Pakistan's medical schools may be excellent starting posts as the country is beset with communicable and non-communicable diseases that are shaped by evolution. Remarkably, Pakistani medical students are open to studying and incorporating EM into their training. Understanding the principles of EM could empower them to tackle growing health problems in the country. Additionally, some difficulties that western medical schools face in integrating EM into their curriculum may not be a hindrance in Pakistan. We propose solutions for the remaining challenges, including obstinate religious sentiments. Herein, we make the case that incorporating EM is particularly important in developing countries such as Pakistan and that it is achievable in its medical student body. PMID:29492264

  18. [Developing a harmonised system for the recognition of clinical trials for veterinary product registration].

    PubMed

    Maliandi, F S

    2008-12-01

    The increase of commerce between developing countries requires a harmonised system for accepting the results of clinical trials (CT) of veterinary products, similar to those that exist in developed countries. The objective of this paper is to propose a basis for the creation of a system that harmonises CTs for approving veterinary products (VP) for registration. Such a system would be a step towards unifying the CTs of different countries, while maintaining country-specific variations that are compatible with the scientific method, international standards, and the principles of objectivity, transparency and confidentiality. Basic requirements to be fulfilled by both private institutions and public offices are described, as are professional responsibilities and possible administrative procedures that could be adapted in each country. The conclusion reached is that a harmonised system is feasible, as has been demonstrated in numerous countries throughout the world. A harmonised system will result in a more efficient product approval process, a reduction in costs, greater transparency in controls, an improvement in the reliability of the health system, and a reduction in the time the process takes. It will also contribute to animal welfare by avoiding the need to repeat trials. The author acknowledges that there are cultural, technological and economic limitations and that these problems, and others, have yet to be overcome.

  19. International variation in the prevalence of preclinical colorectal cancer: Implications for predictive values of noninvasive screening tests and potential target populations for screening

    PubMed Central

    Stock, Christian; Brenner, Hermann

    2017-01-01

    Screening for colorectal cancer (CRC) is implemented in an increasing number of countries. We aimed to assess international variation in the prevalence of preclinical CRC and the resulting variation in positive and negative predictive values (PPVs, NPVs) of existing and potential CRC screening tests in various countries. Using age‐ and sex‐specific CRC incidence data and transition rates from preclinical to clinical CRC we estimated overall and age‐ and sex‐specific prevalence of preclinical CRC in the target population aged 50–74 years in different parts of the world. These prevalence estimates were used to derive PPVs and NPVs for existing and potential noninvasive screening tests with varying levels of sensitivity and specificity. Within all regions and countries, prevalence strongly increases with age and is higher in men than in women. In addition, major variation was seen between regions and countries, with overall prevalence varying between 1 and 0.1%. As a result, PPVs are expected to strongly vary between ∼10% for men in high incidence countries, such as Australia and Germany, and 1% for women in low incidence countries, whereas NPVs are expected to be consistently well above 99%. Variation in CRC prevalence profoundly affects expected PPVs of screening tests, and PPVs should be carefully considered when decisions on screening tests and strategies are made for specific populations and health care systems. Here, we provide estimates of preclinical CRC and expected PPVs and NPVs of noninvasive screening tests, which may enhance the empirical basis for planning of population‐based CRC screening strategies. PMID:28670788

  20. HIV service delivery models towards 'Zero AIDS-related Deaths': a collaborative case study of 6 Asia and Pacific countries.

    PubMed

    Fujita, Masami; Poudel, Krishna C; Green, Kimberly; Wi, Teodora; Abeyewickreme, Iyanthi; Ghidinelli, Massimo; Kato, Masaya; Vun, Mean Chhi; Sopheap, Seng; San, Khin Ohnmar; Bollen, Phavady; Rai, Krishna Kumar; Dahal, Atul; Bhandari, Durga; Boas, Peniel; Yaipupu, Jessica; Sirinirund, Petchsri; Saonuam, Pairoj; Duong, Bui Duc; Nhan, Do Thi; Thu, Nguyen Thi Minh; Jimba, Masamine

    2015-04-24

    In the Asia-Pacific region, limited systematic assessment has been conducted on HIV service delivery models. Applying an analytical framework of the continuum of prevention and care, this study aimed to assess HIV service deliveries in six Asia and Pacific countries from the perspective of service availability, linking approaches and performance monitoring for maximizing HIV case detection and retention. Each country formed a review team that provided published and unpublished information from the national HIV program. Four types of continuum were examined: (i) service linkages between key population outreach and HIV diagnosis (vertical-community continuum); (ii) chronic care provision across HIV diagnosis and treatment (chronological continuum); (iii) linkages between HIV and other health services (horizontal continuum); and (iv) comprehensive care sites coordinating care provision (hub and heart of continuum). Regarding the vertical-community continuum, all districts had voluntary counselling and testing (VCT) in all countries except for Myanmar and Vietnam. In these two countries, limited VCT availability was a constraint for referring key populations reached. All countries monitored HIV testing coverage among key populations. Concerning the chronological continuum, the proportion of districts/townships having antiretroviral treatment (ART) was less than 70% except in Thailand, posing a barrier for accessing pre-ART/ART care. Mechanisms for providing chronic care and monitoring retention were less developed for VCT/pre-ART process compared to ART process in all countries. On the horizontal continuum, the availability of HIV testing for tuberculosis patients and pregnant women was limited and there were sub-optimal linkages between tuberculosis, antenatal care and HIV services except for Cambodia and Thailand. These two countries indicated higher HIV testing coverage than other countries. Regarding hub and heart of continuum, all countries had comprehensive care sites with different degrees of community involvement. The analytical framework was useful to identify similarities and considerable variations in service availability and linking approaches across the countries. The study findings would help each country critically adapt and adopt global recommendations on HIV service decentralization, linkages and integration. Especially, the findings would inform cross-fertilization among the countries and national HIV program reviews to determine county-specific measures for maximizing HIV case detection and retention.

  1. [Vaccines: producers in countries of the Southern hemisphere].

    PubMed

    Bertrand, J J

    2007-08-01

    Vaccine producers in southern hemisphere countries now contribute significantly to global output. In 2006 southern hemisphere countries accounted for more than 10% of the total worldwide production with a progression approximately 70% greater than all producers combined in the two-year period between 2004 and 2006. Though difficult to measure, production in volume is higher due to lower prices practiced in most of these countries. For many years before the 1980s, production was scattered among numerous limited-scale companies. Most were founded at the initiative of governments striving to cover the needs of the population for essential vaccines. A number of institutions and private structures such as Institut Pasteur Production, Connaught Laboratories, and Institut Merieux have also set up production facilities. Today's producers can be divided into two categories, i.e., local producers that produce mainly monovalent vaccines and worldwide producers with strong R&D investment programs. Local producers are located mainly in large southern hemisphere countries such as China, India, Brazil, and Indonesia as well as in eastern countries. For the most dynamic companies, international development is focused on southern hemisphere countries excluding North America and Europe. With the support international organization such as WHO, UNICEF and GAVI, alliances are now being formed and networks are being organized in an effort to ensure reliable supplies of high quality vaccines at affordable prices in developing countries. The contribution of these producers will increase for the greater benefit of the people living in the southern hemisphere.

  2. National Testing of Pupils in Europe: Objectives, Organisation and Use of Results

    ERIC Educational Resources Information Center

    Parveva, Teodora; De Coster, Isabelle; Noorani, Sogol

    2009-01-01

    This study produced by the Eurydice network gives a detailed picture of the context and organisation of national tests in 30 European countries and the use made of test results in informing education policy and practice and in guiding the school career of pupils. It presents the diverse choices made by European countries regarding the objectives,…

  3. Hepatitis B testing and vaccination in immigrants attending English as a second language classes in British Columbia, Canada.

    PubMed

    Hislop, T Gregory; Bajdik, Chris D; Teh, Chong; Lam, Wendy; Tu, Shin-Ping; Yasui, Yutaka; Bastani, Roshan; Taylor, Vicky M

    2009-01-01

    Hepatitis B virus (HBV) is a growing health issue in Canada, especially given that population growth is now largely the result of immigration. Immigrants from countries with high HBV prevalence and low levels of HBV vaccination have an excess risk of liver disease and there is a need for increased diligence in HBV blood testing and possibly vaccination among these populations. This study describes the sociodemographic characteristics associated with a history of HBV testing and HBV vaccination in immigrants from several countries with high HBV prevalence who are attending English classes. 759 adult immigrants attending English as a Second Language classes completed a self-administered questionnaire asking about sociodemographic characteristics and history of HBV testing and HBV vaccination. Descriptive statistics and adjusted ORs were calculated to explore these associations. 71% reported prior HBV testing, 8% reported vaccination without testing, and 21% reported neither testing nor vaccination. Age, education and country of birth all showed significant effects for both testing and vaccination. Health care practitioners need to be cognizant of HBV testing, and possibly vaccination, in some of their patients, including immigrants from countries with endemic HBV infection. Infected persons need to be identified by blood testing in order receive necessary care to prevent or delay the onset of liver disease as well as to adopt appropriate behaviours to reduce the risk of transmission to others. Close contacts of infected persons also require HBV testing and subsequent vaccination (if not infected) or medical management (if infected).

  4. Earth physicist describes US nuclear test monitoring system

    NASA Astrophysics Data System (ADS)

    1986-01-01

    The U. S. capabilities to monitor underground nuclear weapons tests in the USSR was examined. American methods used in monitoring the underground nuclear tests are enumerated. The U. S. technical means of monitoring Solviet nuclear weapons testing, and whether it is possible to conduct tests that could not be detected by these means are examined. The worldwide seismic station network in 55 countries available to the U. S. for seismic detection and measurement of underground nuclear explosions, and also the systems of seismic research observatories in 15 countries and seismic grouping stations in 12 countries are outlined including the advanced computerized data processing capabilities of these facilities. The level of capability of the U. S. seismic system for monitoring nuclear tests, other, nonseismic means of monitoring, such as hydroacoustic and recording of effects in the atmosphere, ionosphere, and the Earth's magnetic field, are discussed.

  5. Long Term Association of Tropospheric Trace gases over Pakistan by exploiting satellite observations and development of Econometric Regression based Model

    NASA Astrophysics Data System (ADS)

    Zeb, Naila; Fahim Khokhar, Muhammad; Khan, Saud Ahmed; Noreen, Asma; Murtaza, Rabbia

    2017-04-01

    Air pollution is the expected key environmental issue of Pakistan as it is ranked among top polluted countries in the region. Ongoing rapid economic growth without any adequate measures is leading to worst air quality over time. The study aims to monitor long term atmospheric composition and association of trace gases over Pakistan. Tropospheric concentrations of CO, TOC, NO2 and HCHO derived from multiple satellite instruments are used for study from year 2005 to 2014. The study will provide first database for tropospheric trace gases over Pakistan. Spatio-temporal assessment identified hotspots and possible sources of trace gases over the Pakistan. High concentrations of trace gases are mainly observed over Punjab region, which may be attributed to its metropolitan importance. It is the major agricultural, industrialized and urbanized (nearly 60 % of the Pakistan's population) sector of the country. The expected sources are the agricultural fires, biomass/fossil fuel burning for heating purposes, urbanization, industrialization and meteorological variations. Seasonal variability is observed to explore seasonal patterns over the decade. Well defined seasonal cycles of trace gases are observed over the whole study period. The observed seasonal patterns also showed some noteworthy association among trace gases, which is further explored by different statistical tests. Seasonal Mann Kendall test is applied to test the significance of trend in series whereas correlation is carried out to measure the strength of association among trace gases. Strong correlation is observed for trace gases especially between CO and TOC. Partial Mann Kendall test is used to ideally identify the impact of each covariate on long term trend of CO and TOC by partialling out each correlating trace gas (covariate). It is observed that TOC, NO2 and HCHO has significant impact on long term trend of CO whereas, TOC critically depends on NO2 concentrations for long term increase over the region. Furthermore to explore causal relation, regression analysis is employed to estimate model for CO and TOC. This model numerically estimated the long term association of trace gases over the region.

  6. Unmet clinical needs in cervical cancer screening.

    PubMed

    Rao, Jianyu; Escobar-Hoyos, Luisa; Shroyer, Kenneth R

    2016-01-01

    Cancer rates worldwide are expected to increase disproportionally in coming decades relative to the projected increase in population, especially in the developing world. The general unavailability of the Pap test and the cost of the HPV test in the developing world have precluded the deployment of effective cervical cancer screening programs in many developing countries. Recent improvements in testing technology arise from a need to overcome the significant limitations of the Pap test and HPV test, but results require first-world technology and validation. Developing countries, where cervical cancer remains one of the most important causes of cancer death, have the greatest need for an affordable, easy-to-use, and highly reliable cancer screening method that can return a diagnosis through efficient laboratory analysis or, more easily, at a woman's point of care. While research, testing, and vaccine improvements in recent years continue to lower the incidence of cervical cancer in some developed countries such as the U.S., HPV testing research needs to do more than test for the presence of virus. The tests must determine the presence and progression of cervical disease. Tests should be more sensitive and specific than Pap tests and Pap-related tests, and should be accurate in more than 90 percent of cases. Tests also need to be low-cost, objective, and easy to perform so screening programs can be widely implemented in developing countries where the need for a better cervical cancer screening test is highest. Such tests may be available through the recent advances in specific biomarkers of cervical cancer and multiplex detection technologies. Development of the next generation of cervical cancer tests that are more specific, sensitive, and informative than the traditional Pap or HPV test will make a significant impact on the reduction of cervical cancer worldwide.

  7. [Internship-test reveals increased knowledge gaps].

    PubMed

    Östgren, Carl-Johan; Krook-Brandt, Margareta; Carlborg, Andreas

    2016-04-08

    We present the results of the medical knowledge test after fulfilled internship for Swedish medical authorization during the years 2009 to the spring of 2015. A total of 7,613 tests were analyzed. Interns graduated from Swedish universities failed in 2.7% to 3.8% of the test moments. Interns who graduated from countries within the European Union (EU) failed in 21.2% and interns graduated from a non-EU country failed in 41.6%. The results from those who graduated from EU and non-EU countries have worsened compared to an earlier study in 2009. Proper measures have now to be implemented for doctors graduated from a non-Swedish university to improve the outcome and introduction to the Swedish health care system.

  8. International survey of cochlear implant candidacy.

    PubMed

    Vickers, D; De Raeve, L; Graham, J

    2016-04-01

    The goal of this work was to determine international differences in candidacy based on audiometric and speech perception measures, and to evaluate the information in light of the funding structure and access to implants within different countries. An online questionnaire was circulated to professionals in 25 countries. There were 28 respondents, representing the candidacy practice in 17 countries. Results showed differences in the funding model between countries. Unilateral implants for both adults and children and bilateral implants for children were covered by national funding in approximately 60% of countries (30% used medical insurance, and 10% self-funding). Fewer countries provided bilateral implants routinely for adults: national funding was available in only 22% (37% used medical insurance and 41% self-funding). Main evolving candidacy areas are asymmetric losses, auditory neuropathy spectrum disorders and electro-acoustic stimulation. For countries using speech-based adult candidacy assessments, the majority (40%) used word tests, 24% used sentence tests, and 36% used a mixture of both. For countries using audiometry for candidacy (70-80% of countries), the majority used levels of 75-85 dB HL at frequencies above 1 kHz. The United Kingdom and Belgium had the most conservative audiometric criteria, and countries such as Australia, Germany, and Italy were the most lenient. Countries with a purely self-funding model had greater flexibility in candidacy requirements.

  9. The Globalization of Science Education

    ERIC Educational Resources Information Center

    DeBoer, George E.

    2011-01-01

    Standards-based science education, with its emphasis on monitoring and accountability, is rapidly becoming a key part of the globalization of science education. Standards-based testing within countries is increasingly being used to determine the effectiveness of a country's educational system, and international testing programs such as Programme…

  10. Quantitative analysis of contents and volatile emissions from a-copaene and quercivorol lures, and longevity for attraction of Euwallacea nr. fornicatus in Florida

    USDA-ARS?s Scientific Manuscript database

    Ambrosia beetles in the cryptic species complex Euwallacea nr. fornicatus vector a fungal pathogen responsible for Fusarium dieback, a disease that impacts avocado (Persea americana) and numerous native trees in the USA (California, Florida), Israel, and other countries. Currently, these pests are d...

  11. Thermal inactivation of non-0157:H7 shiga-toxin producing Escherichia coli (STEC) in catfish fillets

    USDA-ARS?s Scientific Manuscript database

    Non-O157:H7 Shiga-toxin producing Escherichia coli (STECs) are emerging pathogens which have been involved in numerous foodborne illness outbreaks. It is not unusual for STEC associated foodborne illness outbreaks to be associated with consumption of fish in many countries. In this study catfish fi...

  12. Tying Early Childhood Education More Closely to Schooling: Promise, Perils and Practical Problems

    ERIC Educational Resources Information Center

    Halpern, Robert

    2013-01-01

    Background: Over the past decade or so, the idea of joining early childhood education (ECE) and schooling has gained currency in the educational reform arena. Numerous education reform proposals and plans include ECE as a component. Scores of school districts around the country have added preschool classrooms to at least some of their elementary…

  13. Focus on Cultural Issues in Research: Developing and Implementing Native American Postcolonial Participatory Action Research.

    ERIC Educational Resources Information Center

    Stone, Joseph B.

    Indian country presents even the most seasoned and careful researcher with numerous methodological issues. Two of the most salient of these are appropriate understanding of postcolonial stress in tribal communities, and the use of participatory action research methods and models in a culturally sensitive manner. This paper explains postcolonial…

  14. Tutoring Programs for Struggling Readers: The America Reads Challenge. Rutgers Invitational Symposia on Education.

    ERIC Educational Resources Information Center

    Morrow, Lesley Mandel, Ed.; Woo, Deborah Gee, Ed.

    As a result of the America Reads Challenge Act of 1997, numerous tutoring programs have been established to help ensure that every child reads independently by the end of third grade. This book describes exemplary America Reads programs across the country as well as other effective early literacy interventions, including Reading Recovery, the…

  15. Common Timberland Tax Questions and Answers

    Treesearch

    William C. Siegel

    1999-01-01

    I recieve numerous letters and telephone calls from non-industrial forest landowners throughout the country who have timber tax questions. Many of the questions I've been asked during the last year should also be of interest to the readers of National Woodlands. I've therefore selected some of them and my answers, for this issue's "Timber and...

  16. Future Developments of Educational Research in the Asia-Pacific Region: Paradigm Shifts, Reforms, and Practice

    ERIC Educational Resources Information Center

    Cheng, Yin Cheong

    2007-01-01

    In facing up to the challenges and impacts of globalization, high technology, economic transformation, international competitions and local developments in the new century, there have been numerous educational reforms and initiatives in many countries in the Asia-Pacific Region (Cheng, 2005a, A new paradigm for re-engineering education:…

  17. Volunteer Scientist-in-the-Classroom Partnership in Metropolitan Nashville Public Schools

    ERIC Educational Resources Information Center

    Tuschl, Jeannie

    2008-01-01

    In 1897, long before the entertainment industry made Nashville famous with country music and the Grand Ole Opry, the city was known as the "Athens of the South," with numerous institutions of higher learning. A century later, four of Nashville's oldest universities have united to promote science education in Metropolitan Nashville Public Schools…

  18. Globalization, National Identity, and Citizenship Education: China's Search for Modernization and a Modern Chinese Citizenry

    ERIC Educational Resources Information Center

    Law, Wing-Wah

    2013-01-01

    Since the early 20th century, numerous scholars have proposed theories and models describing, interpreting, and suggesting the development paths countries have taken or should take. None of these, however, can fully explain China's efforts, mainly through education and citizenship education, to modernize itself and foster a modern citizenry since…

  19. Teachers' Perception of Mobile Edutainment for Special Needs Learners: The Malaysian Case

    ERIC Educational Resources Information Center

    Mohd Yusof, Anuar; Daniel, Esther Gnanamalar Sarojini; Low, Wah Yun; Ab. Aziz, Kamarulzaman

    2014-01-01

    Study of Malaysian adoption of mobile learning (m-learning) is still in the early stages. However, there are numerous researchers in the country exploring the potential and application of m-learning in the Malaysian education system, including special education. A key question is whether teachers are prepared to incorporate mobile technology as…

  20. Do You See What I See? Understanding Filipino Elderly's Needs, Benefits, and Expectations from an Adult Continuing Education Program

    ERIC Educational Resources Information Center

    Escolar Chua, Rowena L.; de Guzman, Allan B.

    2014-01-01

    As the elderly population increases, encouraging older adults to participate in lifelong learning has become a priority for many countries. Properly structured lifelong learning programs have consistently yielded numerous benefits to older adults; therefore, careful attention and effort should be exerted to ensure its effectiveness by involving…

  1. Promoting Reading Attitudes of Girls and Boys: A New Challenge for Educational Policy? Multi-Group Analyses across Four European Countries

    ERIC Educational Resources Information Center

    Nonte, Sonja; Hartwich, Lea; Willems, Ariane S.

    2018-01-01

    Background: Numerous studies have investigated the relationships between various student, home and contextual factors and reading achievement. However, the relationship between such factors and reading attitudes has been investigated far less, despite the fact that theoretical frameworks of large-scale assessments and school effectiveness research…

  2. "Virginity Is a Virtue: Prevent Early Sex"--Teacher Perceptions of Sex Education in a Ugandan Secondary School

    ERIC Educational Resources Information Center

    Iyer, Padmini; Aggleton, Peter

    2014-01-01

    Sex education is a politically contentious issue in many countries, and there are numerous, competing ideologies relating to the most appropriate methods to teach young people about sexual and reproductive health. This paper examines policy and practice in Uganda in light of two contrasting ideologies, namely morally conservative and comprehensive…

  3. Teachers' Risk Perception and Needs in Addressing Infectious Disease Outbreak

    ERIC Educational Resources Information Center

    Wong, Emmy M. Y.; Cheng, May M. H.; Lo, S.K.

    2010-01-01

    The outbreak of the Influenza A (H1N1) virus has led to numerous precautionary school closures in several countries. No research is available on the school teachers' perceptions as a health protective resource in controlling communicable disease outbreaks. The purposes of this study were to examine the risk perception, the perceived understanding…

  4. International Norms in the Reform of Romanian Higher Education: A Discursive Analysis

    ERIC Educational Resources Information Center

    Deca, Ligia

    2015-01-01

    Higher education systems in Central and Eastern Europe have faced numerous challenges in their transitions following the collapse of totalitarian regimes in 1989-1990. Romania, as a country that is representative of the specificities of this particular region, as well as a relatively new member of the European Union, is a privileged site for…

  5. The Best Laid Plans: Components of Quality Campus Environments in Europe.

    ERIC Educational Resources Information Center

    Gerber, Carole

    A group of American university facility planners and architects paid a 2-week visit in September 1987 to eight universities in five countries in order to study and explore European campuses at first hand. A description of the tour illustrated by numerous color photographs of the universities visited is presented in this report. Both the visitors…

  6. An Opportunity to Lead Sustainably: The Benefits and Considerations of Student-Led Green Revolving Fund Projects

    ERIC Educational Resources Information Center

    Kononenko, Kevin

    2012-01-01

    In recent years, energy- and resource-reduction projects have compelled student leaders to create sustainability projects on campuses across the country. This paper examines the role that students play in green revolving funds, including identification, approval, and management. After speaking with numerous students on a variety of campuses, it is…

  7. Implementing Free Primary Education Policy in Malawi and Ghana: Equity and Efficiency Analysis

    ERIC Educational Resources Information Center

    Inoue, Kazuma; Oketch, Moses

    2008-01-01

    Malawi and Ghana are among the numerous Sub-Saharan Africa countries that have in recent years introduced Free Primary Education (FPE) policy as a means to realizing the 2015 Education for All and Millennium Development Goals international targets. The introduction of FPE policy is, however, a huge challenge for any national government that has…

  8. Teaching the New Vietnam: It's a Country, Not a War

    ERIC Educational Resources Information Center

    McCornac, Dennis C.

    2008-01-01

    Vietnam has made remarkable progress over the past two decades in its transition to a market economy resulting in numerous changes to both its social and economic institutions. It is a nation at peace focusing on economic development and integrating into the world economy. Although the tragic events in Vietnam's history cannot be forgotten, the…

  9. A Causal Inference Analysis of the Effect of Wildland Fire Smoke on Ambient Air Pollution Levels and Health Burden

    EPA Science Inventory

    Wildfire smoke is a major contributor to ambient air pollution levels. In this talk, we develop a spatio-temporal model to estimate the contribution of fire smoke to overall air pollution in different regions of the country. We combine numerical model output with observational da...

  10. Personalized Mobile English Vocabulary Learning System Based on Item Response Theory and Learning Memory Cycle

    ERIC Educational Resources Information Center

    Chen, C. M.; Chung, C. J.

    2008-01-01

    Since learning English is very popular in non-English speaking countries, developing modern assisted-learning tools that support effective English learning is a critical issue in the English-language education field. Learning English involves memorization and practice of a large number of vocabulary words and numerous grammatical structures.…

  11. How Does Formal Leadership Influence a District Content Coaching Program?

    ERIC Educational Resources Information Center

    Hudson, Sarah E.

    2010-01-01

    The titles of professional books on the topic of coaching are numerous, coaching professional development offerings are widespread and schools across the country are hiring teachers to serve in coaching roles. There is great interest around the topic of coaching and much is being written about the support that is needed for coaches as well.…

  12. Demographic Change and the Life Circumstances of Immigrant Families

    ERIC Educational Resources Information Center

    Hernandez, Donald J.

    2004-01-01

    Several major demographic shifts over the past half-century have transformed who we are and how we live in this country in many ways. Most striking, however, is the fact that children today are much more likely to be members of ethnic or racial minority groups. Racial/ethnic minorities are destined, in aggregate, to become the numerical majority…

  13. Prevention of Dengue Fever: An Exploratory School-Community Intervention Involving Students Empowered as Change Agents

    ERIC Educational Resources Information Center

    Jayawardene, Wasantha P.; Lohrmann, David K.; YoussefAgha, Ahmed H.; Nilwala, Dayani C.

    2011-01-01

    Background: Dengue fever and dengue hemorrhagic fever (DF/DHF) are epidemic and endemic in tropical and subtropical countries including Sri Lanka. Numerous structural and community interventions have been shown to be effective in interrupting the life cycle of mosquitoes that transmit DF/DHF; however, these interventions are not always implemented…

  14. School Enrolment and Attendance for Children with Disabilities in Kenya: An Examination of Household Survey Data

    ERIC Educational Resources Information Center

    Moyi, Peter

    2017-01-01

    While evidence confirms that children with disabilities face significant obstacles to schooling, especially in low-income countries like Kenya, there is limited empirical research on which to develop policy. The government of Kenya has long neglected the plight of people with disabilities. Despite numerous policy recommendations from the various…

  15. Advancement of Children's Rights in Africa: A Social Justice Framework for School Psychologists

    ERIC Educational Resources Information Center

    Pillay, Jace

    2014-01-01

    The United Nations Convention on Children's Rights and the subsequent African Charter on the Rights and Welfare of the Child together with the Bill of Children's Rights and numerous other policies and regulations in many African countries have set the precedent for children's rights to be respected and implemented across the African Continent.…

  16. Choosing appropriate subpopulations for modeling tree canopy cover nationwide

    Treesearch

    Gretchen G. Moisen; John W. Coulston; Barry T. Wilson; Warren B. Cohen; Mark V. Finco

    2012-01-01

    In prior national mapping efforts, the country has been divided into numerous ecologically similar mapping zones, and individual models have been constructed for each zone. Additionally, a hierarchical approach has been taken within zones to first mask out areas of nonforest, then target models of tree attributes within forested areas only. This results in many models...

  17. Housing and construction markets

    Treesearch

    Delton Alderman

    2013-01-01

    The UNECE region's economic recovery has been sluggish; national income in more than half of the region’s countries has yet to return to 2008 levels and unemployment remains high. Numerous risks remain that could endanger even moderate growth in 2014 and beyond as the eurozone crisis appears to be deepening. Further deterioration in the eurozone or an economic...

  18. Four Rationales of HE Internationalization: Perspectives of U.K. Universities on Attracting Students from Former Soviet Countries

    ERIC Educational Resources Information Center

    Chankseliani, Maia

    2018-01-01

    In the context marked by increasing competition between nation-states and universities, expanding individualization, growing influence of nonstate actors, and the new reality of Brexit, this study uses narrative and numeric data to explore the rationales of U.K. higher education (HE) internationalization, specifically motives of attracting…

  19. Modelling of Factors Influencing Gender Difference in Mathematics Achievement Using TIMSS 2011 Data for Singaporean Eighth Grade Students

    ERIC Educational Resources Information Center

    Yoo, Yang Seok

    2018-01-01

    Numerous studies have attributed gender difference in mathematics achievement to various sociocultural influences. Singapore is a country of higher gender equality as represented in the Global Gender Gap Index and Singaporean girls perform as well or higher than boys in international mathematics assessments. This study develops a conceptual model…

  20. Did Unilateral Divorce Laws Raise Divorce Rates in Western Europe?

    ERIC Educational Resources Information Center

    Kneip, Thorsten; Bauer, Gerrit

    2009-01-01

    The increase in European divorce rates over the past decades was accompanied by several changes in divorce laws. Yet for European countries, research on the effects of divorce law on the divorce rate is scarce. Most of the existing studies are based on data from North America and provide numerous, but inconsistent, results. We use fixed-effects…

  1. Online Learning in Singapore Primary Schools: An Interview with Seng Chee Tan

    ERIC Educational Resources Information Center

    Hawthorne, Elizabeth; Tan, Seng Chee

    2005-01-01

    The Southeast Asian country of Singapore comprises a main island and numerous islets between Malaysia and Indonesia. Inhabited by Chinese, Malays, Indians, Eurasians, and other ethnic populations, Singapore is a vibrant mix of different cultures and religions. It is also reputed to be the most wired island in the world. This characteristic--along…

  2. The Effects of Community Factors on School Participation in Turkey: A Multilevel Analysis

    ERIC Educational Resources Information Center

    Gumus, Sedat

    2014-01-01

    Turkey, like many developing countries, is facing considerable problems in terms of low school attendance rates, late enrolment and early dropout of girls in particular. Numerous studies have already been conducted, both in Turkey and elsewhere, to determine the factors affecting school enrolment of boys and girls. Existing studies in Turkey,…

  3. High School Male and Female Learning-Style Similarities and Differences in Diverse Nations.

    ERIC Educational Resources Information Center

    Honigsfeld, Andrea; Dunn, Rita

    2003-01-01

    Investigated gender differences in the learning styles of high school boys and girls from Bermuda, Brunei, Hungary, Sweden, and New Zealand. Data from student surveys indicated that although boys' and girls' learning styles differed in numerous ways, individuals within each group were more unique then either group as a whole. Country-specific…

  4. Euthanasia: Murder or Not: A Comparative Approach

    PubMed Central

    BANOVIĆ, Božidar; TURANJANIN, Veljko

    2014-01-01

    Abstract Background Euthanasia is one of the most intriguing ethical, medical and law issues that marked whole XX century and beginning of the XXI century, sharply dividing scientific and unscientific public to its supporters and opponents. It also appears as one of the points where all three major religions (Catholic, Orthodox, and Islamic) have the same view. They are strongly against legalizing mercy killing, emphasizing the holiness of life as a primary criterion by which the countries should start in their considerations. Studying criminal justice systems in the world, the authors concluded that the issue of deprivation of life from compassion is solved on three ways. On the first place, we have countries where euthanasia is murder like any other murder from the criminal codes. Second, the most numerous are states where euthanasia is murder committed under privilege circumstances. On the third place, in the Western Europe we have countries where euthanasia is a legal medical procedure, under requirements prescribed by the law. In this paper, authors have made a brief comparison of the solutions that exist in some Islamic countries, where euthanasia is a murder, with Western countries, where it represents completely decriminalized medical procedure. PMID:26056652

  5. Experimental and numerical study of drill bit drop tests on Kuru granite

    NASA Astrophysics Data System (ADS)

    Fourmeau, Marion; Kane, Alexandre; Hokka, Mikko

    2017-01-01

    This paper presents an experimental and numerical study of Kuru grey granite impacted with a seven-buttons drill bit mounted on an instrumented drop test machine. The force versus displacement curves during the impact, so-called bit-rock interaction (BRI) curves, were obtained using strain gauge measurements for two levels of impact energy. Moreover, the volume of removed rock after each drop test was evaluated by stereo-lithography (three-dimensional surface reconstruction). A modified version of the Holmquist-Johnson-Cook (MHJC) material model was calibrated using Kuru granite test results available from the literature. Numerical simulations of the single drop tests were carried out using the MHJC model available in the LS-DYNA explicit finite-element solver. The influence of the impact energy and additional confining pressure on the BRI curves and the volume of the removed rock is discussed. In addition, the influence of the rock surface shape before impact was evaluated using two different mesh geometries: a flat surface and a hyperbolic surface. The experimental and numerical results are compared and discussed in terms of drilling efficiency through the mechanical specific energy. This article is part of the themed issue 'Experimental testing and modelling of brittle materials at high strain rates'.

  6. Early Gender Test Score Gaps across OECD Countries

    ERIC Educational Resources Information Center

    Bedard, Kelly; Cho, Insook

    2010-01-01

    The results reported in this paper contribute to the debate about gender skill gaps in at least three ways. First, we document the large differences in early gender gaps across developed countries using a large scale, modern, representative data source. Second, we show that countries with pro-female sorting, countries that place girls in classes…

  7. Numerical Weather Prediction Models on Linux Boxes as tools in meteorological education in Hungary

    NASA Astrophysics Data System (ADS)

    Gyongyosi, A. Z.; Andre, K.; Salavec, P.; Horanyi, A.; Szepszo, G.; Mille, M.; Tasnadi, P.; Weidiger, T.

    2012-04-01

    Education of Meteorologist in Hungary - according to the Bologna Process - has three stages: BSc, MSc and PhD, and students graduating at each stage get the respective degree (BSc, MSc and PhD). The three year long base BSc course in Meteorology can be chosen by undergraduate students in the fields of Geosciences, Environmental Sciences and Physics. BasicsFundamentals in Mathematics (Calculus), Physics (General and Theoretical) Physics and Informatics are emphasized during their elementary education. The two year long MSc course - in which about 15 to 25 students are admitted each year - can be studied only at our the Eötvös Loránd uUniversity in the our country. Our aim is to give a basic education in all fields of Meteorology. Main topics are: Climatology, Atmospheric Physics, Atmospheric Chemistry, Dynamic and Synoptic Meteorology, Numerical Weather Prediction, modeling Modeling of surfaceSurface-atmosphere Iinteractions and Cclimate change. Education is performed in two branches: Climate Researcher and Forecaster. Education of Meteorologist in Hungary - according to the Bologna Process - has three stages: BSc, MSc and PhD, and students graduating at each stage get the respective degree. The three year long BSc course in Meteorology can be chosen by undergraduate students in the fields of Geosciences, Environmental Sciences and Physics. Fundamentals in Mathematics (Calculus), (General and Theoretical) Physics and Informatics are emphasized during their elementary education. The two year long MSc course - in which about 15 to 25 students are admitted each year - can be studied only at the Eötvös Loránd University in our country. Our aim is to give a basic education in all fields of Meteorology: Climatology, Atmospheric Physics, Atmospheric Chemistry, Dynamic and Synoptic Meteorology, Numerical Weather Prediction, Modeling of Surface-atmosphere Interactions and Climate change. Education is performed in two branches: Climate Researcher and Forecaster. Numerical modeling became a common tool in the daily practice of weather experts forecasters due to the i) increasing user demands for weather data by the costumers, ii) the growth in computer resources, iii) numerical weather prediction systems available for integration on affordable, off the shelf computers and iv) available input data (from ECMWF or NCEP) for model integrations. Beside learning the theoretical basis, since the last year. Students in their MSc or BSc Thesis Research or in Student's Research ProjectsStudent's Research Projects h have the opportunity to run numerical models and to analyze the outputs for different purposes including wind energy estimation, simulation of the dynamics of a polar low, and subtropical cyclones, analysis of the isentropic potential vorticity field, examination of coupled atmospheric dispersion models, etc. A special course in the application of numerical modeling has been held (is being announced for the upcoming semester) (is being announced for the upcoming semester) for our students in order to improve their skills on this field. Several numerical model (NRIPR ETA and WRF) systems have been adapted in the University and integrated WRF have been tested and used for the geographical region of the Carpathian Basin (NRIPR, ETA and WRF). Recently ALADIN/CHAPEAU the academic version of the ARPEGE ALADIN cy33t1 meso-scale numerical weather prediction model system (which is the operational forecasting tool of our National Weather Service) has been installed at our Institute. ALADIN is the operational forecasting model of the Hungarian Meteorological Service and developed in the framework of the international ALADIN co-operation. Our main objectives are i) the analysis of different typical weather situations, ii) fine tuning of parameterization schemes and the iii) comparison of the ALADIN/CHAPEAU and WRF model outputs based on case studies. The necessary hardware and software innovations has have been done. In the presentation the computer resources needed for the integration of both WRF and ALADIN/CHAPEAU models will be briefly described. The software developments performed for the evaluation and comparison of the different modeling systems will be demonstrated. The main objectives of the education program on the practical numerical weather modeling will be introduced, as well as its detailed thematics and the structure of the labs.

  8. Testing and numerical modeling of hypervelocity impact damaged Space Station multilayer insulation

    NASA Technical Reports Server (NTRS)

    Rule, William K.

    1992-01-01

    Results are presented of experiments measuring the degradation of the insulating capabilities of the multilayer insulation (MLI) of the Space Station Freedom, when subjected to hypervelocity impact damage. A simple numerical model was developed for use in an engineering design environment for quick assessment of thermal effect of the impact. The model was validated using results from thermal vacuum tests on MLI with simulated damage. The numerical model results agreed with experimental data.

  9. Review of policy and status of implementation of collaborative HIV-TB activities in 23 high-burden countries.

    PubMed

    Gupta, S; Granich, R; Date, A; Lepere, P; Hersh, B; Gouws, E; Samb, B

    2014-10-01

    Issuance of national policy guidance is a critical step to ensure quality HIV-TB (human immunodeficiency virus-tuberculosis) coordination and programme implementation. From the database of the Joint United Nations Programme on HIV/AIDS (UNAIDS), we reviewed 62 national HIV and TB guidelines from 23 high-burden countries for recommendations on HIV testing for TB patients, criteria for initiating antiretroviral therapy (ART) and the Three I's for HIV/TB (isoniazid preventive treatment [IPT], intensified TB case finding and TB infection control). We used UNAIDS country-level programme data to determine the status of implementation of existing guidance. Of the 23 countries representing 89% of the global HIV-TB burden, Brazil recommends ART irrespective of CD4 count for all people living with HIV, and four (17%) countries recommend ART at the World Health Organization (WHO) 2013 guidelines level of CD4 count ⩿500 cells/mm(3) for asymptomatic persons. Nineteen (83%) countries are consistent with WHO 2013 guidelines and recommend ART for HIV-positive TB patients irrespective of CD4 count. IPT is recommended by 16 (70%) countries, representing 67% of the HIV-TB burden; 12 recommend symptom-based screening alone for IPT initiation. Guidelines from 15 (65%) countries with 79% of the world's HIV-TB burden include recommendations on HIV testing and counselling for TB patients. Although uptake of ART, HIV testing for TB patients, TB screening for people living with HIV and IPT have increased significantly, progress is still limited in many countries. There is considerable variance in the timing and content of national policies compared with WHO guidelines. Missed opportunities to implement new scientific evidence and delayed adaptation of existing WHO guidance remains a key challenge for many countries.

  10. Rotavirus vaccine RIX4414 (Rotarix™): a pharmacoeconomic review of its use in the prevention of rotavirus gastroenteritis in developing countries.

    PubMed

    Plosker, Greg L

    2011-11-01

    This article provides an overview of the clinical profile of rotavirus vaccine RIX4414 (Rotarix™) in the prevention of rotavirus gastroenteritis (RVGE) in developing countries, followed by a comprehensive review of pharmacoeconomic analyses with the vaccine in low- and middle-income countries. RVGE is associated with significant morbidity and mortality among children <5 years of age in developing countries. The protective efficacy of a two-dose oral series of rotavirus vaccine RIX4414 has been demonstrated in several well designed clinical trials conducted in developing countries, and the 'real-world' effectiveness of the vaccine has also been shown in naturalistic and case-control trials after the introduction of universal vaccination programmes with RIX4414 in Latin American countries. The WHO recommends universal rotavirus vaccination programmes for all countries. Numerous modelled cost-effectiveness analyses have been conducted with rotavirus vaccine RIX4414 across a wide range of low- and middle-income countries. Although data sources and assumptions varied across studies, results of the analyses consistently showed that the introduction of the vaccine as part of a national vaccination programme would be very (or highly) cost effective compared with no rotavirus vaccination programme, according to widely used cost-effectiveness thresholds for developing countries. Vaccine price was not known at the time the analyses were conducted and had to be estimated. In sensitivity analyses, rotavirus vaccine RIX4414 generally remained cost effective at the highest of a range of possible vaccine prices considered. Despite these favourable results, decisions regarding the implementation of universal vaccination programmes with RIX4414 may also be contingent on budgetary and other factors, underscoring the importance of subsidized vaccination programmes for poor countries through the GAVI Alliance (formerly the Global Alliance for Vaccines and Immunization).

  11. Wilga Photonics and Web Engineering 2011

    NASA Astrophysics Data System (ADS)

    Romaniuk, Ryszard S.

    2011-10-01

    The paper presents a digest of chosen technical work results shown by young researchers from different technical universities from this country during the SPIE-IEEE Wilga 2011 symposium on Photonics and Web Engineering. Topical tracks of the symposium embraced, among others, nanomaterials and nanotechnologies for photonics, sensory and nonlinear optical fibers, object oriented design of hardware, photonic metrology, optoelectronics and photonics applications, photonics-electronics co-design, optoelectronic and electronic systems for astronomy and high energy physics experiments, JET and pi-of-the sky experiments development. The symposium is an annual summary in the development of numerable Ph.D. theses carried out in this country in the area of advanced electronic and photonic systems. It is also a great occasion for SPIE, IEEE, OSA and PSP students to meet together in a large group spanning the whole country with guests from this part of Europe. A digest of Wilga references is presented [1-225].

  12. The two cultures of health worker migration: a Pacific perspective.

    PubMed

    Connell, John

    2014-09-01

    Migration of health workers from relatively poor countries has been sustained for more than half a century. The rationale for migration has been linked to numerous factors relating to the economies and health systems of source and destination countries. The contemporary migration of health workers is also embedded in a longstanding and intensifying culture of migration, centred on the livelihoods of extended households, and a medical culture that is oriented to superior technology and advanced skills. This dual culture is particularly evident in small island states in the Pacific, but is apparent in other significant migrant source countries in the Caribbean, Sub-Saharan Africa and Asia. Family expectations of the benefits of migration indicate that regulating the migration and attrition of health workers necessitates more complex policies beyond those evident within health care systems alone. Copyright © 2014. Published by Elsevier Ltd.

  13. Tooth follicle extirpation and uvulectomy.

    PubMed

    Johnston, N L; Riordan, P J

    2005-12-01

    Migration is not only the movement of people, but also of their culture, customs and beliefs. As more people from developing countries in Africa migrate to industrialized countries, the more likely health professionals will find themselves providing care for people of whose customs and practices they have little knowledge. This review of the literature suggests that removal of deciduous canine follicles and uvulectomy are frequently practised in some African and neighbouring countries. Reasons given for deciduous canine extirpation include the prevention of vomiting, fever and diarrhoea. The indications for uvulectomy appear widespread, including treatment for persistent fever, coughing and growth retardation. The practices are usually performed by traditional healers. Risks for children who undergo these procedures are extensive, including septicaemia, potential for HIV transmission, numerous dental complications and death. With improved understanding between Western health teams and local, traditional people, an improved system may develop whereby the two systems can work together in providing improved health outcomes for the people.

  14. Epidemiology, aetiology and management of visual impairment in children.

    PubMed

    Solebo, Ameenat Lola; Rahi, Jugnoo

    2014-04-01

    An estimated 19 million of the world's children are visually impaired, while 1.4 million are blind. Using the UK as a model for high income countries, from a population-based incidence study, the annual cumulative incidence of severe visual impairment/blindness (SVL/BL) is estimated to be 6/10 000 by age 15 years, with the incidence being highest in the first year of life. The population of visually impaired children within high, middle and lower income countries differ considerably between and within countries. The numerous and mainly uncommon disorders which can cause impaired vision result in heterogeneous population which includes a substantial proportion (for SVI/BL, the majority) of children with additional systemic disorders or impairments whose needs differ substantially from those with isolated vision impairment. Paediatricians and other paediatric professionals have a key role in early detection and multidisciplinary management to minimise the impact of visual impairment (VI) in childhood.

  15. [Chronic obstructive pulmonary disease (COPD) and the interior environment].

    PubMed

    Khayath, N; Qi, S; de Blay, F

    2016-10-01

    In COPD, the risk attributable to smoking is very variable according to published studies. A significant number shows that the risk of COPD in non-smokers is far from negligible. The links between COPD and pollution of the interior environment vary between developed and developing countries. In developing countries, numerous studies have shown a link between COPD and exposure to substances derived from the combustion of biomass fuels, particularly in women where the exposure is the greatest. Nevertheless, a cause and effect relationship has not always been demonstrated. In developed countries, there is no evidence of a role of exposure to domestic interior pollution in the genesis of COPD and interior pollutants such as NO 2  and particulates seem only to aggravate already existing COPD. Further studies are necessary to evaluate their role in COPD and explore the underlying mechanisms. Irritative phenomena could be involved. Copyright © 2016 SPLF. Published by Elsevier Masson SAS. All rights reserved.

  16. Global Reach of an Internet Smoking Cessation Intervention among Spanish- and English-Speaking Smokers from 157 Countries

    PubMed Central

    Barrera, Alinne Z.; Pérez-Stable, Eliseo J.; Delucchi, Kevin L.; Muñoz, Ricardo F.

    2009-01-01

    This investigation is a secondary analysis of demographic, smoking, and depression information in a global sample of Spanish- and English-speaking smokers who participated in a series of randomized controlled smoking cessation trials conducted via the Internet. The final sample consisted of 17,579 smokers from 157 countries. Smoking profiles were similar across languages and world regions and consistent with characteristics of participants in traditional smoking cessation studies. Participants were predominantly Spanish-speakers, evenly divided between men and women and relatively few indicated using traditional smoking cessation methods (e.g., groups or medication). This study demonstrates that substantial numbers of smokers from numerous countries seek Web-based smoking cessation resources and adds to the growing support for Web-assisted tobacco interventions as an additional tool to address the need for global smoking cessation efforts. PMID:19440423

  17. The Death of the West: An alternative view.

    PubMed

    Coleman, David; Basten, Stuart

    2015-01-01

    Much has been written about the 'Death of the West', a demise threatened by the low level of reproduction in Western countries. That fate is contrasted unfavourably with the rapid growth of the populations and economies of less developed countries, and the prospect of the numerical and political marginalization of the formerly dominant developed world. We believe that trends in European fertility have been misunderstood and that, with effort and some pain, their consequences for age structure are manageable. Many European societies also enjoy the advantages of demographic and social maturity, the resilience of established consensual democratic institutions, the rule of law, and civil society. The sizes of China and India raise problems of resource sustainability and vulnerability to climate change. China risks falling into a low-fertility trap, reinforced by urban working conditions unfriendly to family formation. Traditional patriarchal and familist cultures may depress fertility rates to unhelpfully low levels in other less developed countries.

  18. Minimizing the dependency ratio in a population with below-replacement fertility through immigration

    PubMed Central

    Simon, C.; Belyakov, A.O.; Feichtinger, G.

    2012-01-01

    Many industrialized countries face fertility rates below replacement level, combined with declining mortality especially in older ages. Consequently, the populations of these countries have started to age. One important indicator of age structures is the dependency ratio which is the ratio of the nonworking age population to the working age population. In this work we find the age-specific immigration profile that minimizes the dependency ratio in a stationary population with below-replacement fertility. It is assumed that the number of immigrants per age is limited. We consider two alternative policies. In the first one, we fix the total number of people who annually immigrate to a country. In the second one, we prescribe the size of the receiving country’s population. For both cases we provide numerical results for the optimal immigration profile, for the resulting age structure of the population, as well as for the dependency ratio. PMID:22781918

  19. Parametric methods outperformed non-parametric methods in comparisons of discrete numerical variables.

    PubMed

    Fagerland, Morten W; Sandvik, Leiv; Mowinckel, Petter

    2011-04-13

    The number of events per individual is a widely reported variable in medical research papers. Such variables are the most common representation of the general variable type called discrete numerical. There is currently no consensus on how to compare and present such variables, and recommendations are lacking. The objective of this paper is to present recommendations for analysis and presentation of results for discrete numerical variables. Two simulation studies were used to investigate the performance of hypothesis tests and confidence interval methods for variables with outcomes {0, 1, 2}, {0, 1, 2, 3}, {0, 1, 2, 3, 4}, and {0, 1, 2, 3, 4, 5}, using the difference between the means as an effect measure. The Welch U test (the T test with adjustment for unequal variances) and its associated confidence interval performed well for almost all situations considered. The Brunner-Munzel test also performed well, except for small sample sizes (10 in each group). The ordinary T test, the Wilcoxon-Mann-Whitney test, the percentile bootstrap interval, and the bootstrap-t interval did not perform satisfactorily. The difference between the means is an appropriate effect measure for comparing two independent discrete numerical variables that has both lower and upper bounds. To analyze this problem, we encourage more frequent use of parametric hypothesis tests and confidence intervals.

  20. Assessment of Cognitive Abilities in Multiethnic Countries: The Case of the Wolof and Mandinka in the Gambia

    ERIC Educational Resources Information Center

    Jukes, Matthew C. H.; Grigorenko, Elena L.

    2010-01-01

    Background: The use of cognitive tests is increasing in Africa but little is known about how such tests are affected by the great ethnic and linguistic diversity on the continent. Aim: To assess ethnic and linguistic group differences in cognitive test performance in the West African country of the Gambia and to investigate the sources of these…

  1. Vibration and noise analysis of a gear transmission system

    NASA Technical Reports Server (NTRS)

    Choy, F. K.; Qian, W.; Zakrajsek, J. J.; Oswald, F. B.

    1993-01-01

    This paper presents a comprehensive procedure to predict both the vibration and noise generated by a gear transmission system under normal operating conditions. The gearbox vibrations were obtained from both numerical simulation and experimental studies using a gear noise test rig. In addition, the noise generated by the gearbox vibrations was recorded during the experimental testing. A numerical method was used to develop linear relationships between the gearbox vibration and the generated noise. The hypercoherence function is introduced to correlate the nonlinear relationship between the fundamental noise frequency and its harmonics. A numerical procedure was developed using both the linear and nonlinear relationships generated from the experimental data to predict noise resulting from the gearbox vibrations. The application of this methodology is demonstrated by comparing the numerical and experimental results from the gear noise test rig.

  2. Numerical investigation of the flow inside the combustion chamber of a plant oil stove

    NASA Astrophysics Data System (ADS)

    Pritz, B.; Werler, M.; Wirbser, H.; Gabi, M.

    2013-10-01

    Recently a low cost cooking device for developing and emerging countries was developed at KIT in cooperation with the company Bosch und Siemens Hausgeräte GmbH. After constructing an innovative basic design further development was required. Numerical investigations were conducted in order to investigate the flow inside the combustion chamber of the stove under variation of different geometrical parameters. Beyond the performance improvement a further reason of the investigations was to rate the effects of manufacturing tolerance problems. In this paper the numerical investigation of a plant oil stove by means of RANS simulation will be presented. In order to reduce the computational costs different model reduction steps were necessary. The simulation results of the basic configuration compare very well with experimental measurements and problematic behaviors of the actual stove design could be explained by the investigation.

  3. Apollo-Soyuz test project docking system

    NASA Technical Reports Server (NTRS)

    Swan, W. L., Jr.

    1976-01-01

    The United States and Soviet Union in July 1975 successfully completed a joint space mission utilizing each country's spacecraft and the compatible docking system designed and fabricated by each country. The compatible docking system is described, along with the extensive research, development, and testing leading up to the successful mission. It also describes the formulation and implementation of methods for breaking the language barrier, bridging the extensive distances for communication and travel, and adjusting to each country's different culture during the three-year development program.

  4. Learning Linear Spatial-Numeric Associations Improves Accuracy of Memory for Numbers

    PubMed Central

    Thompson, Clarissa A.; Opfer, John E.

    2016-01-01

    Memory for numbers improves with age and experience. One potential source of improvement is a logarithmic-to-linear shift in children’s representations of magnitude. To test this, Kindergartners and second graders estimated the location of numbers on number lines and recalled numbers presented in vignettes (Study 1). Accuracy at number-line estimation predicted memory accuracy on a numerical recall task after controlling for the effect of age and ability to approximately order magnitudes (mapper status). To test more directly whether linear numeric magnitude representations caused improvements in memory, half of children were given feedback on their number-line estimates (Study 2). As expected, learning linear representations was again linked to memory for numerical information even after controlling for age and mapper status. These results suggest that linear representations of numerical magnitude may be a causal factor in development of numeric recall accuracy. PMID:26834688

  5. Learning Linear Spatial-Numeric Associations Improves Accuracy of Memory for Numbers.

    PubMed

    Thompson, Clarissa A; Opfer, John E

    2016-01-01

    Memory for numbers improves with age and experience. One potential source of improvement is a logarithmic-to-linear shift in children's representations of magnitude. To test this, Kindergartners and second graders estimated the location of numbers on number lines and recalled numbers presented in vignettes (Study 1). Accuracy at number-line estimation predicted memory accuracy on a numerical recall task after controlling for the effect of age and ability to approximately order magnitudes (mapper status). To test more directly whether linear numeric magnitude representations caused improvements in memory, half of children were given feedback on their number-line estimates (Study 2). As expected, learning linear representations was again linked to memory for numerical information even after controlling for age and mapper status. These results suggest that linear representations of numerical magnitude may be a causal factor in development of numeric recall accuracy.

  6. Marshall Space Flight Center's Impact Testing Facility Capabilities

    NASA Technical Reports Server (NTRS)

    Finchum, Andy; Hubbs, Whitney; Evans, Steve

    2008-01-01

    Marshall Space Flight Center s (MSFC) Impact Testing Facility (ITF) serves as an important installation for space and missile related materials science research. The ITF was established and began its research in spacecraft debris shielding in the early 1960s, then played a major role in the International Space Station debris shield development. As NASA became more interested in launch debris and in-flight impact concerns, the ITF grew to include research in a variety of impact genres. Collaborative partnerships with the DoD led to a wider range of impact capabilities being relocated to MSFC as a result of the closure of Particle Impact Facilities in Santa Barbara, California. The Particle Impact Facility had a 30 year history in providing evaluations of aerospace materials and components during flights through rain, ice, and solid particle environments at subsonic through hypersonic velocities. The facility s unique capabilities were deemed a "National Asset" by the DoD. The ITF now has capabilities including environmental, ballistic, and hypervelocity impact testing utilizing an array of air, powder, and two-stage light gas guns to accommodate a variety of projectile and target types and sizes. Numerous upgrades including new instrumentation, triggering circuitry, high speed photography, and optimized sabot designs have been implemented. Other recent research has included rain drop demise characterization tests to obtain data for inclusion in on-going model development. The current and proposed ITF capabilities range from rain to micrometeoroids allowing the widest test parameter range possible for materials investigations in support of space, atmospheric, and ground environments. These test capabilities including hydrometeor, single/multi-particle, ballistic gas guns, exploding wire gun, and light gas guns combined with Smooth Particle Hydrodynamics Code (SPHC) simulations represent the widest range of impact test capabilities in the country.

  7. Numerical solution of special ultra-relativistic Euler equations using central upwind scheme

    NASA Astrophysics Data System (ADS)

    Ghaffar, Tayabia; Yousaf, Muhammad; Qamar, Shamsul

    2018-06-01

    This article is concerned with the numerical approximation of one and two-dimensional special ultra-relativistic Euler equations. The governing equations are coupled first-order nonlinear hyperbolic partial differential equations. These equations describe perfect fluid flow in terms of the particle density, the four-velocity and the pressure. A high-resolution shock-capturing central upwind scheme is employed to solve the model equations. To avoid excessive numerical diffusion, the considered scheme avails the specific information of local propagation speeds. By using Runge-Kutta time stepping method and MUSCL-type initial reconstruction, we have obtained 2nd order accuracy of the proposed scheme. After discussing the model equations and the numerical technique, several 1D and 2D test problems are investigated. For all the numerical test cases, our proposed scheme demonstrates very good agreement with the results obtained by well-established algorithms, even in the case of highly relativistic 2D test problems. For validation and comparison, the staggered central scheme and the kinetic flux-vector splitting (KFVS) method are also implemented to the same model. The robustness and efficiency of central upwind scheme is demonstrated by the numerical results.

  8. Practical guidance for the implementation of stress echocardiography.

    PubMed

    Suzuki, Kengo; Hirano, Yutaka; Yamada, Hirotsugu; Murata, Mitsushige; Daimon, Masao; Takeuchi, Masaaki; Seo, Yoshihiro; Izumi, Chisato; Akaishi, Makoto

    2018-06-06

    Exercise stress testing has been widely undertaken for the diagnosis of heart diseases. The accurate assessment of clinical conditions can be conducted by comparing the findings obtained from the results of stress echocardiography with the changes in the blood/heart rate and electrocardiograms. Numerous overseas studies have reported the utility of stress echocardiography in diagnosing myocardial ischemia; in Japan, the use of this modality for this purpose was included in the national health insurance reimbursable list in 2012. Nevertheless, stress echocardiography is far from being a widespread practice in Japan. This might be due to insufficient equipment (e.g., ergometers, space for test implementation) at each medical institution, shortage of technicians and sonographers who are well experienced and who are responsible for obtaining images during stress testing. The other possible reasons include the limited evidence available in Japan and the lack of a standardized testing protocol. Further dissemination of the practice of exercise stress echocardiography in this country is deemed necessary to establish satisfactory evidence for the use of stress echocardiography in the Japanese population. To this end, efforts are underway to develop a standardized protocol and report format to be adopted throughout Japan. We here present a guideline created by the Guideline Development Committee of the Japanese Society of Echocardiography that describes safe and effective stress echocardiography protocols and report formats. The readers are encouraged to perform exercise stress echocardiography using the proposed template for consensus document and report attached to this guideline.

  9. Effects of Non-Symbolic Approximate Number Practice on Symbolic Numerical Abilities in Pakistani Children.

    PubMed

    Khanum, Saeeda; Hanif, Rubina; Spelke, Elizabeth S; Berteletti, Ilaria; Hyde, Daniel C

    2016-01-01

    Current theories of numerical cognition posit that uniquely human symbolic number abilities connect to an early developing cognitive system for representing approximate numerical magnitudes, the approximate number system (ANS). In support of this proposal, recent laboratory-based training experiments with U.S. children show enhanced performance on symbolic addition after brief practice comparing or adding arrays of dots without counting: tasks that engage the ANS. Here we explore the nature and generality of this effect through two brief training experiments. In Experiment 1, elementary school children in Pakistan practiced either a non-symbolic numerical addition task or a line-length addition task with no numerical content, and then were tested on symbolic addition. After training, children in the numerical training group completed the symbolic addition test faster than children in the line length training group, suggesting a causal role of brief, non-symbolic numerical training on exact, symbolic addition. These findings replicate and extend the core findings of a recent U.S. laboratory-based study to non-Western children tested in a school setting, attesting to the robustness and generalizability of the observed training effects. Experiment 2 tested whether ANS training would also enhance the consistency of performance on a symbolic number line task. Over several analyses of the data there was some evidence that approximate number training enhanced symbolic number line placements relative to control conditions. Together, the findings suggest that engagement of the ANS through brief training procedures enhances children's immediate attention to number and engagement with symbolic number tasks.

  10. Patient safety: numerical skills and drug calculation abilities of nursing students and registered nurses.

    PubMed

    McMullan, Miriam; Jones, Ray; Lea, Susan

    2010-04-01

    This paper is a report of a correlational study of the relations of age, status, experience and drug calculation ability to numerical ability of nursing students and Registered Nurses. Competent numerical and drug calculation skills are essential for nurses as mistakes can put patients' lives at risk. A cross-sectional study was carried out in 2006 in one United Kingdom university. Validated numerical and drug calculation tests were given to 229 second year nursing students and 44 Registered Nurses attending a non-medical prescribing programme. The numeracy test was failed by 55% of students and 45% of Registered Nurses, while 92% of students and 89% of nurses failed the drug calculation test. Independent of status or experience, older participants (> or = 35 years) were statistically significantly more able to perform numerical calculations. There was no statistically significant difference between nursing students and Registered Nurses in their overall drug calculation ability, but nurses were statistically significantly more able than students to perform basic numerical calculations and calculations for solids, oral liquids and injections. Both nursing students and Registered Nurses were statistically significantly more able to perform calculations for solids, liquid oral and injections than calculations for drug percentages, drip and infusion rates. To prevent deskilling, Registered Nurses should continue to practise and refresh all the different types of drug calculations as often as possible with regular (self)-testing of their ability. Time should be set aside in curricula for nursing students to learn how to perform basic numerical and drug calculations. This learning should be reinforced through regular practice and assessment.

  11. Effects of Non-Symbolic Approximate Number Practice on Symbolic Numerical Abilities in Pakistani Children

    PubMed Central

    Khanum, Saeeda; Hanif, Rubina; Spelke, Elizabeth S.; Berteletti, Ilaria; Hyde, Daniel C.

    2016-01-01

    Current theories of numerical cognition posit that uniquely human symbolic number abilities connect to an early developing cognitive system for representing approximate numerical magnitudes, the approximate number system (ANS). In support of this proposal, recent laboratory-based training experiments with U.S. children show enhanced performance on symbolic addition after brief practice comparing or adding arrays of dots without counting: tasks that engage the ANS. Here we explore the nature and generality of this effect through two brief training experiments. In Experiment 1, elementary school children in Pakistan practiced either a non-symbolic numerical addition task or a line-length addition task with no numerical content, and then were tested on symbolic addition. After training, children in the numerical training group completed the symbolic addition test faster than children in the line length training group, suggesting a causal role of brief, non-symbolic numerical training on exact, symbolic addition. These findings replicate and extend the core findings of a recent U.S. laboratory-based study to non-Western children tested in a school setting, attesting to the robustness and generalizability of the observed training effects. Experiment 2 tested whether ANS training would also enhance the consistency of performance on a symbolic number line task. Over several analyses of the data there was some evidence that approximate number training enhanced symbolic number line placements relative to control conditions. Together, the findings suggest that engagement of the ANS through brief training procedures enhances children's immediate attention to number and engagement with symbolic number tasks. PMID:27764117

  12. Reliability, Factor Structure, and Measurement Invariance of the Dominic Interactive Across European Countries: Cross-Country Utility of a Child Mental Health Self-Report

    PubMed Central

    Kuijpers, Rowella C. W. M.; Otten, Roy; Vermulst, Ad A.; Bitfoi, Adina; Goelitz, Dietmar; Koç, Ceren; Mihova, Zlatka; Pez, Ondine; Carta, Mauro; Keyes, Katherine; Lesinskiene, Sigita; Engels, Rutger C. M. E.; Kovess, Viviane

    2015-01-01

    Large-scale international surveys are important to globally evaluate, monitor, and promote children's mental health. However, use of young children's self-reports in these studies is still controversial. The Dominic Interactive, a computerized DSM-IV–based child mental health self-report questionnaire, has unique characteristics that may make it preeminently appropriate for usage in cross-country comparisons. This study aimed to determine scale score reliabilities (omega) of the Dominic Interactive in a sample of 8,135 primary school children, ages 6–11 years old, in 7 European countries, to confirm the proposed 7-scale factor structure, and to test for measurement invariance of scale and item scores across countries. Omega reliability values for scale scores were good to high in every country, and the factor structure was confirmed for all countries. A thorough examination of measurement invariance provided evidence for cross-country test score comparability of 5 of the 7 scales and partial scale score invariance of 2 anxiety scales. Possible explanations for this partial invariance include cross-country differences in conceptualizing items and defining what is socially and culturally acceptable anxiety. The convincing evidence for validity of score interpretation makes the Dominic Interactive an indispensable tool for cross-country screening purposes. PMID:26237209

  13. Democracy predicts sport and recreation membership: Insights from 52 countries.

    PubMed

    Balish, Shea M

    2017-03-01

    Although evidence suggests sport and recreation are powerful contributors to worldwide public health, sizable gender differences persist. It is unknown whether country characteristics moderate gender differences across countries. The primary purpose of this study was to examine if countries' levels of democracy and/or gender inequality moderate gender differences in sport and recreation membership across countries. The secondary purpose was to examine if democracy and/or gender inequality predicts overall rates of sport and recreation membership for both males and females. This study involved a nested cross-sectional design and employed the sixth wave (2013) of the world value survey (n Ss =71,901, n countries =52). Multiple hierarchal nonlinear Bernoulli models tested: (1) if countries' levels of democracy moderate gender differences in sport and recreation membership; and (2) if democracy is associated with increased sport and recreation membership for both males and females. Countries' level of democracy fully moderated gender differences in sport and recreation membership across countries. Moreover, democracy was positively associated with both male and female membership, even when controlling for individual and country-level covariates. Democratic political regimes may confer health benefits via increased levels of sport and recreation membership, especially for females. Future research should test mediating mechanisms. Copyright © 2016 Ministry of Health, Saudi Arabia. Published by Elsevier Ltd. All rights reserved.

  14. Physiological Profiles of High School Female Cross Country Runners.

    ERIC Educational Resources Information Center

    Butts, Nancy Kay

    1982-01-01

    Percentage of body fat, ratings of perceived exertion, and maximal oxygen consumption were obtained during a continuous running treadmill test on 127 high school female cross country runners. The relatively low relationships between the variables tested and running performance indicated that other factors may be more important determinants of…

  15. Cultural values: can they explain self-reported health?

    PubMed

    Roudijk, Bram; Donders, Rogier; Stalmeier, Peep

    2017-06-01

    Self-reported health (SRH) is a measure widely used in health research and population studies. Differences in SRH have been observed between countries and cultural values have been hypothesized to partly explain such differences. Cultural values can be operationalized by two cultural dimensions using the World Values Survey (WVS), namely the traditional/rational-secular and the survival/self-expression dimension. We investigate whether there is an association between the WVS cultural dimensions and SRH, both within and between countries. Data from 51 countries in the WVS is used and combined with macroeconomic data from the Worldbank database. The association between SRH and the WVS cultural dimensions is tested within each of the 51 countries and multilevel mixed models are used to test differences between these countries. Socio-demographic and macroeconomic variables are used to correct for non-cultural variables related to SRH. Within countries, the survival/self-expression dimension was positively associated with SRH, while in most countries there was a negative association for the traditional/rational-secular dimension. Values range between 4 and 17% within countries. Further analyses show that the associations within countries and between countries are similar. Controlling for macroeconomic and socio-demographic factors did not change our results. The WVS cultural dimensions predict SRH within and between countries. Contrary to our expectations, traditional/rational-secular values were negatively associated with SRH. As SRH is associated with cultural values between countries, cultural values could be considered when interpreting SRH between countries.

  16. Experimental and numerical study of a 10MW TLP wind turbine in waves and wind

    NASA Astrophysics Data System (ADS)

    Pegalajar-Jurado, Antonio; Hansen, Anders M.; Laugesen, Robert; Mikkelsen, Robert F.; Borg, Michael; Kim, Taeseong; Heilskov, Nicolai F.; Bredmose, Henrik

    2016-09-01

    This paper presents tests on a 1:60 version of the DTU 10MW wind turbine mounted on a tension leg platform and their numerical reproduction. Both the experimental setup and the numerical model are Froude-scaled, and the dynamic response of the floating wind turbine to wind and waves is compared in terms of motion in the six degrees of freedom, nacelle acceleration and mooring line tension. The numerical model is implemented in the aero-elastic code Flex5, featuring the unsteady BEM method and the Morison equation for the modelling of aerodynamics and hydrodynamics, respectively. It was calibrated with the tests by matching key system features, namely the steady thrust curve and the decay tests in water. The calibrated model is used to reproduce the wind-wave climates in the laboratory, including regular and irregular waves, with and without wind. The model predictions are compared to the measured data, and a good agreement is found for surge and heave, while some discrepancies are observed for pitch, nacelle acceleration and line tension. The addition of wind generally improves the agreement with test results. The aerodynamic damping is identified in both tests and simulations. Finally, the sources of the discrepancies are discussed and some improvements in the numerical model are suggested in order to obtain a better agreement with the experiments.

  17. Impact of military on biofuels consumption and GHG emissions: the evidence from G7 countries.

    PubMed

    Bildirici, Melike

    2018-05-01

    It was aimed to test the relation among the greenhouse gases emissions, economic growth, biofuels consumption, and militarization in G7 countries during the 1985-2015 period by Pedroni 1995 and panel Johansen tests and two long-run estimators-dynamic OLS and fully modified OLS. Long-run estimators found that economic growth and militarization have statistically significant positive impact on CO 2 emission of G7 countries. Furthermore, the panel causality tests were applied: Dumitrescu and Hurlin (Econ Model 29(4):1450-1460, 2012) and panel Granger causality. These tests determined the causal relationship between the variables. The results of this paper implied that economic growth and biofuels consumption depend on militarization, and economic growth and militarization are granger causes of the greenhouse gases emissions.

  18. Biomarker Testing for Personalized Therapy in Lung Cancer in Low- and Middle-Income Countries.

    PubMed

    Hirsch, Fred R; Zaric, Bojan; Rabea, Ahmed; Thongprasert, Sumitra; Lertprasertsuke, Nirush; Dalurzo, Mercedes Liliana; Varella-Garcia, Marileila

    2017-01-01

    There have been many important advances in personalized therapy for patients with lung cancer, particularly for those with advanced disease. Molecular testing is crucial for implementation of personalized therapy. Although the United States and many Western countries have come far in the implementation of personalized therapy for lung cancer, there are substantial challenges for low- and middle-income countries (LMICs). Globally, the LMICs display great heterogeneity in the pattern of implementation of molecular testing and targeted therapy. The current review presents an attempt to identify the challenges and obstacles for the implementation of molecular testing and the use of targeted therapies in these areas. Lack of infrastructure, lack of technical expertise, economic factors, and lack of access to new drugs are among the substantial barriers.

  19. Hepatitis B Testing and Vaccination in Immigrants Attending English as a Second Language Classes in British Columbia, Canada

    PubMed Central

    Hislop, T Gregory; Bajdik, Chris D; Teh, Chong; Lam, Wendy; Tu, Shin-Ping; Yasui, Yutaka; Bastani, Roshan; Taylor, Vicky M

    2010-01-01

    Background Hepatitis B virus (HBV) is a growing health issue in Canada, especially given that population growth is now largely the result of immigration. Immigrants from countries with high HBV prevalence and low levels of HBV vaccination have an excess risk of liver disease and there is a need for increased diligence in HBV blood testing and possibly vaccination among these populations. Objective This study describes the sociodemographic characteristics associated with a history of HBV testing and HBV vaccination in immigrants from several countries with high HBV prevalence who are attending English classes. Methods 759 adult immigrants attending English as a Second Language classes completed a self-administered questionnaire asking about sociodemographic characteristics and history of HBV testing and HBV vaccination. Descriptive statistics and adjusted ORs were calculated to explore these associations. Results 71% reported prior HBV testing, 8% reported vaccination without testing, and 21% reported neither testing nor vaccination. Age, education and country of birth all showed significant effects for both testing and vaccination. Conclusions Health care practitioners need to be cognizant of HBV testing, and possibly vaccination, in some of their patients, including immigrants from countries with endemic HBV infection. Infected persons need to be identified by blood testing in order receive necessary care to prevent or delay the onset of liver disease as well as to adopt appropriate behaviours to reduce the risk of transmission to others. Close contacts of infected persons also require HBV testing and subsequent vaccination (if not infected) or medical management (if infected). PMID:20192572

  20. Quality assurance for HIV point-of-care testing and treatment monitoring assays

    PubMed Central

    Sandstrom, Paul; Denny, Thomas N.; Hurlston, Mackenzie; Ball, Terry B.; Peeling, Rosanna W.; Boeras, Debrah I.

    2016-01-01

    In 2015, UNAIDS launched the 90-90-90 targets aimed at increasing the number of people infected with HIV to become aware of their status, access antiretroviral therapies and ultimately be virally suppressed. To achieve these goals, countries may need to scale up point-of-care (POC) testing in addition to strengthening central laboratory services. While decentralising testing increases patient access to diagnostics, it presents many challenges with regard to training and assuring the quality of tests and testing. To ensure synergies, the London School of Hygiene & Tropical Medicine held a series of consultations with countries with an interest in quality assurance and their implementing partners, and agreed on an external quality assessment (EQA) programme to ensure reliable results so that the results lead to the best possible care for HIV patients. As a result of the consultations, EQA International was established, bringing together EQA providers and implementers to develop a strategic plan for countries to establish national POC EQA programmes and to estimate the cost of setting up and maintaining the programme. With the dramatic increase in the number of proficiency testing panels required for thousands of POC testing sites across Africa, it is important to facilitate technology transfer from global EQA providers to a network of regional EQA centres in Africa for regional proficiency testing panel production. EQA International will continue to identify robust and cost-effective EQA technologies for quality POC testing, integrating novel technologies to support sustainable country-owned EQA programmes in Africa. PMID:28879133

  1. Influence of Installation Effects on Pile Bearing Capacity in Cohesive Soils - Large Deformation Analysis Via Finite Element Method

    NASA Astrophysics Data System (ADS)

    Konkol, Jakub; Bałachowski, Lech

    2017-03-01

    In this paper, the whole process of pile construction and performance during loading is modelled via large deformation finite element methods such as Coupled Eulerian Lagrangian (CEL) and Updated Lagrangian (UL). Numerical study consists of installation process, consolidation phase and following pile static load test (SLT). The Poznań site is chosen as the reference location for the numerical analysis, where series of pile SLTs have been performed in highly overconsolidated clay (OCR ≈ 12). The results of numerical analysis are compared with corresponding field tests and with so-called "wish-in-place" numerical model of pile, where no installation effects are taken into account. The advantages of using large deformation numerical analysis are presented and its application to the pile designing is shown.

  2. Tsunami propagation modelling - a sensitivity study

    NASA Astrophysics Data System (ADS)

    Dao, M. H.; Tkalich, P.

    2007-12-01

    Indian Ocean (2004) Tsunami and following tragic consequences demonstrated lack of relevant experience and preparedness among involved coastal nations. After the event, scientific and forecasting circles of affected countries have started a capacity building to tackle similar problems in the future. Different approaches have been used for tsunami propagation, such as Boussinesq and Nonlinear Shallow Water Equations (NSWE). These approximations were obtained assuming different relevant importance of nonlinear, dispersion and spatial gradient variation phenomena and terms. The paper describes further development of original TUNAMI-N2 model to take into account additional phenomena: astronomic tide, sea bottom friction, dispersion, Coriolis force, and spherical curvature. The code is modified to be suitable for operational forecasting, and the resulting version (TUNAMI-N2-NUS) is verified using test cases, results of other models, and real case scenarios. Using the 2004 Tsunami event as one of the scenarios, the paper examines sensitivity of numerical solutions to variation of different phenomena and parameters, and the results are analyzed and ranked accordingly.

  3. Shallow magma diversions during explosive diatreme-forming eruptions.

    PubMed

    Le Corvec, Nicolas; Muirhead, James D; White, James D L

    2018-04-13

    The diversion of magma is an important mechanism that may lead to the relocation of a volcanic vent. Magma diversion is known to occur during explosive volcanic eruptions generating subterranean excavation and remobilization of country and volcanic rocks. However, feedbacks between explosive crater formation and intrusion processes have not been considered previously, despite their importance for understanding evolving hazards during volcanic eruptions. Here, we apply numerical modeling to test the impacts of excavation and subsequent infilling of diatreme structures on stress states and intrusion geometries during the formation of maar-diatreme complexes. Explosive excavation and infilling of diatremes affects local stress states which inhibits magma ascent and drives lateral diversion at various depths, which are expected to promote intra-diatreme explosions, host rock mixing, and vent migration. Our models demonstrate novel mechanisms explaining the generation of saucer-shaped sills, linked with magma diversion and enhanced intra-diatreme explosive fragmentation during maar-diatreme volcanism. Similar mechanisms will occur at other volcanic vents producing crater-forming eruptions.

  4. Point-of-Care Diagnostics in Low Resource Settings: Present Status and Future Role of Microfluidics

    PubMed Central

    Sharma, Shikha; Zapatero-Rodríguez, Julia; Estrela, Pedro; O’Kennedy, Richard

    2015-01-01

    The inability to diagnose numerous diseases rapidly is a significant cause of the disparity of deaths resulting from both communicable and non-communicable diseases in the developing world in comparison to the developed world. Existing diagnostic instrumentation usually requires sophisticated infrastructure, stable electrical power, expensive reagents, long assay times, and highly trained personnel which is not often available in limited resource settings. This review will critically survey and analyse the current lateral flow-based point-of-care (POC) technologies, which have made a major impact on diagnostic testing in developing countries over the last 50 years. The future of POC technologies including the applications of microfluidics, which allows miniaturisation and integration of complex functions that facilitate their usage in limited resource settings, is discussed The advantages offered by such systems, including low cost, ruggedness and the capacity to generate accurate and reliable results rapidly, are well suited to the clinical and social settings of the developing world. PMID:26287254

  5. Municipal waste management in Sicily: practices and challenges.

    PubMed

    Messineo, Antonio; Panno, Domenico

    2008-01-01

    There are numerous problems yet to be solved in waste management and although efforts towards waste recovery and recycling have been made, landfills are still the most common method used in the EU and many other industrialised countries. Thermal disposal, particularly incineration, is a tested and viable alternative. In 2004, only 11% of the annual waste production of Italy was incinerated. Sicily, with over five million inhabitants, is the second largest region in Italy where waste management is now a critical problem. The use of landfills can no longer be considered a satisfactory environmental solution; therefore, new methods have to be chosen and waste-to-energy plants could provide an answer. This paper gives details of municipal solid waste management in Sicily following a new Waste Management Plan. Four waste-to-energy plants will generate electricity through a steam cycle; the feedstock will become the residue after material recovery, which is calculated as 20-40% weight of the collected municipal solid waste.

  6. French validation of the compulsive internet use scale (CIUS).

    PubMed

    Khazaal, Yasser; Chatton, Anne; Horn, Alessandra; Achab, Sophia; Thorens, Gabriel; Zullino, Daniele; Billieux, Joël

    2012-12-01

    The popularity of using the Internet and related applications has grown in European countries in the last two decades. Despite numerous advantages in terms of optimizing communications among individuals and social systems, the use of the Internet may be associated with excessive use and possible Internet addiction. The goals of the current study were to validate a French version of the compulsive Internet use scale (CIUS) and to assess its links with common psychiatric symptoms such as depression (assessed with the Beck depression inventory: BDI), anxiety (assessed with the trait anxiety inventory: STAI) and alcohol misuse (assessed with the alcohol use disorder identification test: AUDIT). The French versions of the CIUS, BDI, STAI and AUDIT were administered to a sample of Internet users. Exploratory and confirmatory analyses, correlation analysis and logistic regression were performed. As previously found with the original version, a one-factor model of the CIUS had good psychometric properties and fit the data well. Excessive use of the Internet was associated with depressive symptoms.

  7. The Correlation of Arterial Stiffness with Biophysical Parameters and Blood Biochemistry.

    PubMed

    Khiyami, Anamil M; Dore, Fiona J; Mammadova, Aytan; Amdur, Richard L; Sen, Sabyasachi

    2017-05-01

    Type 2 diabetes presents with numerous macrovascular and microvascular impairments, which in turn lead to various co-morbidities. Vascular co-morbidities can be seen when examining arterial stiffness (AS), which is a predictor for endothelial health and cardiovascular disease risk. Pulse wave analysis (PWA) and pulse wave velocity (PWV) are two tests that are commonly used to measure AS. Currently, disease states and progression are tracked via blood biochemistry. These gold standards in monitoring diabetes are expensive and need optimization. To investigate which biophysical and biochemical parameters correlated best with AS, which may reduce the number of biochemical tests and biophysical parameter measurements needed to track disease progression. Data from 42 subjects with type 2 diabetes mellitus for ≤10 years, aged 40-70 years, were analyzed at a single time point. We investigated various blood biochemistry, body composition, and AS parameters. A combination of fat mass and fat-free mass was most associated with PWA over any other parameters. Leptin and high-sensitivity C-reactive protein seem to be the next two parameters that correlate with augmentation index. No other parameters had strong correlations to either PWA or PWV values. Body composition methods seemed to be better predictors of type 2 diabetes mellitus patient's vascular disease progression. Our study indicates that body composition measurements may help replace expensive tests. This may have public health and health surveillance implications in countries facing financial challenges.

  8. Bedroom media: One risk factor for development.

    PubMed

    Gentile, Douglas A; Berch, Olivia N; Choo, Hyekyung; Khoo, Angeline; Walsh, David A

    2017-12-01

    Mass media have numerous effects on children, ranging from influencing school performance to increased or reduced aggression. What we do not know, however, is how media availability in the bedroom moderates these effects. Although several researchers have suggested that bedroom media may influence outcomes by displacing other activities (the displacement hypothesis) or by changing the content of media consumed (the content hypothesis), these have rarely been tested directly. This study tested both hypotheses using several outcomes that are associated with bedroom media and some of the underlying mediating mechanisms. The hypotheses were tested using 3 longitudinal samples of varying methods, age, duration, and country. The results indicate that children who have bedroom media are likely to watch larger amounts of screen time which displaced important activities, such as reading and sleeping, which mediated later negative outcomes such as poor school performance. Bedroom media also influence risk for obesity and video game addiction. Children with bedroom media are also likely to be exposed to more media violence. The violent content increased normative beliefs about aggression, which increased physical aggression, providing support for the content hypothesis. This study demonstrates that media can have effects not just from what they show, but also because of what children are not exposed to. Bedroom media are therefore a robust risk factor for several aspects of child development. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  9. Performance testing of coagulants to reduce stormwater runoff turbidity.

    DOT National Transportation Integrated Search

    2014-05-01

    On December 1, 2009, the US Environmental Protection Agency (EPA) published a rule in the Federal : Register establishing non-numeric and, for the first time, numeric effluent limitation guidelines (ELGs). The : numeric ELGs included a turbidity limi...

  10. Stages and transitions in medical education around the world: clarifying structures and terminology.

    PubMed

    Wijnen-Meijer, Marjo; Burdick, William; Alofs, Lonneke; Burgers, Chantalle; ten Cate, Olle

    2013-04-01

    In a world that increasingly serves the international exchange of information on medical training, many students, physicians and educators encounter numerous variations in curricula, degrees, point of licensing and terminology. The aim of this study was to shed some light for those trying to compare medical training formats across countries. We surveyed a sample of key informants from 40 countries. Survey questions included: structure of medical education, moment that unrestricted practice is allowed, various options after general medical licensing, nomenclature of degrees granted and relevant terminology related to the medical education system. In addition, we searched the literature for description of country-specific information. Based on the results, we described the six models of current medical training around the world, supplemented with a list of degrees granted after medical school and an explanation of frequently used terminology. The results of this questionnaire study lead to the conclusion that while there are many differences between countries, there appear to be six dominant models. The models vary in structure and length of medical training, point of full registration and degrees that are granted.

  11. European guidelines for workplace drug testing in urine.

    PubMed

    Taskinen, Sanna; Beck, Olof; Bosch, Tessa; Brcak, Michaela; Carmichael, Duncan; Fucci, Nadia; George, Claire; Piper, Mark; Salomone, Alberto; Schielen, Wim; Steinmeyer, Stefan; Weinmann, Wolfgang

    2017-06-01

    These European Guidelines for Workplace Drug Testing in Urine have been prepared and updated by the European Workplace Drug Testing Society (EWDTS). The first version of these urine guidelines was published in 2002. Since then, the guidelines have been followed by many laboratories in different European countries and their role has been essential particularly in countries lacking legislation for workplace drug testing. In 2014, the EWDTS started a guidelines updating project and published a new version of the urine guidelines in 2015. Here we represent this updated version of the urine guidelines. The European Guidelines are designed to establish best practice procedures whilst allowing individual countries to operate within the requirements of national customs and legislation. The EWDTS recommends that all European laboratories that undertake legally defensible workplace drug testing should use these guidelines as a template for accreditation. Copyright © 2017 John Wiley & Sons, Ltd. Copyright © 2017 John Wiley & Sons, Ltd.

  12. Proposed Tuberculosis Mass Testing Program for the Third-Country National Indigent Workforce of the Country of Palau

    DTIC Science & Technology

    2010-12-01

    workers upon entry to Palau for TB and the human immunodeficiency virus (HIV), since it can affect testing results and can change the therapy...human immunodeficiency virus (HIV) can affect testing results and can change the therapy recommendations for those patients with MTB, HIV testing...133°30’ E. (Ref 1). Because of the location (latitude and longitude), Palau enjoys a tropical climate year round, with an average temperature of 82

  13. Molecular markers for colorectal cancer screening

    PubMed Central

    Dickinson, Brandon T.; Kisiel, John; Ahlquist, David A.; Grady, William M.

    2016-01-01

    Colorectal cancer (CRC), although a significant cause of morbidity and mortality worldwide, has seen a declining incidence and mortality in countries with programmatic screening. Fecal occult blood testing (FOBT) and endoscopic approaches are the predominant screening methods currently. The discovery of the adenoma→carcinoma sequence and a greater understanding of the genetic and epigenetic changes that drive the formation of CRC have contributed to innovative research to identify molecular markers for highly accurate, non-invasive screening tests for CRC. DNA, proteins, messenger RNA, and micro-RNA have all been evaluated. The observation of tumor cell exfoliation into the mucocellular layer of the colonic epithelium and proven stability of DNA in a harsh stool environment make stool DNA a particularly promising marker. The development of a clinically useful stool DNA test has required numerous technical advances, including optimization in DNA stabilization, the development of assays with high analytical sensitivity, and the identification of specific and broadly informative molecular markers. A multi-target stool DNA (MT-sDNA) test, which combines both mutant and methylated DNA markers and a fecal immunochemical test (FIT), recently performed favorably in a large cross-sectional validation study and has been approved by the US Food and Drug Administration (FDA) for the screening of asymptomatic, average risk individuals. The ultimate way in which molecular marker screening assays will be used in clinical practice will require additional studies to determine optimal screening intervals, factors affecting compliance, management of false positive results, and the use of these assays in high-risk populations, as well as other considerations. PMID:25994221

  14. Evaluation of the base/subgrade soil under repeated loading : phase I--laboratory testing and numerical modeling of geogrid reinforced bases in flexible pavement.

    DOT National Transportation Integrated Search

    2009-10-01

    This report documents the results of a study that was conducted to characterize the behavior of geogrid reinforced base : course materials. The research was conducted through an experimental testing and numerical modeling programs. The : experimental...

  15. Study of radon dispersion in typical dwelling using CFD modeling combined with passive-active measurements

    NASA Astrophysics Data System (ADS)

    Rabi, R.; Oufni, L.

    2017-10-01

    Inhalation of radon (222Rn) and its decay products are a major source of natural radiation exposure. It is known from recent surveys in many countries that radon and its progeny contribute significantly to total inhalation dose and it is fairly established that radon when inhaled in large quantity causes lung disorder. Indoor air conditions and ventilation systems strongly influence the indoor radon concentration. This study focuses on investigating both numerically and experimentally the influence of environmental conditions on the indoor radon concentration and spatial distribution. The numerical results showed that ventilation rate, temperature and humidity have significant impacts on both radon content and distribution. The variations of radon concentration with the ventilation, temperature and relative humidity are discussed. The measurement results show the diurnal variations of the indoor radon concentration are found to exhibit a positive correlation with relative humidity and negatively correlate with the air temperature. The analytic solution is used to validate the numeric results. The comparison amongst analytical, numerical and measurement results shows close agreement.

  16. Technological Innovation and Developmental Strategies for Sustainable Management of Aquatic Resources in Developing Countries

    NASA Astrophysics Data System (ADS)

    Agboola, Julius Ibukun

    2014-12-01

    Sustainable use and allocation of aquatic resources including water resources require implementation of ecologically appropriate technologies, efficient and relevant to local needs. Despite the numerous international agreements and provisions on transfer of technology, this has not been successfully achieved in developing countries. While reviewing some challenges to technological innovations and developments (TID), this paper analyzes five TID strategic approaches centered on grassroots technology development and provision of localized capacity for sustainable aquatic resources management. Three case studies provide examples of successful implementation of these strategies. Success requires the provision of localized capacity to manage technology through knowledge empowerment in rural communities situated within a framework of clear national priorities for technology development.

  17. Technological innovation and developmental strategies for sustainable management of aquatic resources in developing countries.

    PubMed

    Agboola, Julius Ibukun

    2014-12-01

    Sustainable use and allocation of aquatic resources including water resources require implementation of ecologically appropriate technologies, efficient and relevant to local needs. Despite the numerous international agreements and provisions on transfer of technology, this has not been successfully achieved in developing countries. While reviewing some challenges to technological innovations and developments (TID), this paper analyzes five TID strategic approaches centered on grassroots technology development and provision of localized capacity for sustainable aquatic resources management. Three case studies provide examples of successful implementation of these strategies. Success requires the provision of localized capacity to manage technology through knowledge empowerment in rural communities situated within a framework of clear national priorities for technology development.

  18. Water Quality and Management Changes Over the History of Poland.

    PubMed

    Szalinska, Ewa

    2018-01-01

    Poland is one of the countries distinguished by a long and colorful past. Undergoing numerous turbulent socio-economic changes forced by the course of history, Poland is now one of the member states of the European Union. Experiencing low water quantity and high contamination levels in surface waters, Poland is following other EU countries in the effort to reach a "good" water status. Herein are presented impacts of changes in Polish history on water legislation, management, and research, as well as explanations for the perceptible split between engineering and scientific approaches to the aquatic issues. Drawbacks caused by unsatisfactory state research funding for the sciences and division of the water related contemporary scientific interests are also discussed.

  19. Brief historical perspectives of malaria in Iran.

    PubMed

    Azizi, Mohammad Hossein; Bahadori, Moslem

    2013-02-01

    The history of malaria as a serious human disease dates back to ancient times. For centuries, malaria has been a deadly disease with high morbidity and mortality that profoundly impacted the socioeconomic status of endemic countries. However, its causative agent remained unidentified until the last decades of the nineteenth century. There were no effective synthetic anti-malarial agents until the mid-twentieth century. Currently malaria has been eliminated or pre-eliminated in numerous countries; however, this preventable and curable disease remains a significant global health problem. A major concern is drug resistance. Presented here, is a brief look at the history of malaria in Iran and the rest of the world, particularly during the nineteenth and twentieth centuries.

  20. 15 CFR Supplement No. 2 to Part 748 - Unique Application and Submission Requirements

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... tools, dimensional inspection machines, direct numerical control systems, specially designed assemblies... Commerce Control List (§ 774.1 of the EAR)—see Category 5 Part 1 Notes 1 and 2 and Part 2 Note 1. License... containing computers to destinations in Country Group D:1 (See Supplement No. 1 to part 740 of the EAR), or...

  1. 15 CFR Supplement No. 2 to Part 748 - Unique Application and Submission Requirements

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... tools, dimensional inspection machines, direct numerical control systems, specially designed assemblies... Commerce Control List (§ 774.1 of the EAR)—see Category 5 Part 1 Notes 1 and 2 and Part 2 Note 1. License... containing computers to destinations in Country Group D:1 (See Supplement No. 1 to part 740 of the EAR), or...

  2. 15 CFR Supplement No. 2 to Part 748 - Unique Application and Submission Requirements

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... tools, dimensional inspection machines, direct numerical control systems, specially designed assemblies... Commerce Control List (§ 774.1 of the EAR)—see Category 5 Part 1 Notes 1 and 2 and Part 2 Note 1. License... containing computers to destinations in Country Group D:1 (See supplement No. 1 to part 740 of the EAR), or...

  3. Toxicity of selected essential oils, silicone oils, and paraffino oil against the common bed bug, cimex lectularius L. (Hemiptera: Cimicidae)

    USDA-ARS?s Scientific Manuscript database

    The common bed bug (Cimex lectularius L.) resurged in the U.S. and many other countries over the past decade. The need for safe and effective bed bug control products propelled the development of numerous “green pesticides”, mostly with essential oils listed as active ingredients. Various inorganic ...

  4. The Problems of Parental Leave.

    PubMed

    Price, Sean

    2017-10-01

    The United States is the only major industrialized country in the world to not require paid parental leave. Numerous studies have shown that allowing parents time with a newborn makes the child and the parents healthier, both physically and mentally. Many physicians, especially those who work in practices with five or fewer doctors, worry about how to pay for parental leave for themselves and their staff.

  5. Unresolved Issues and New Challenges in Teaching English to Young Learners: The Case of South Korea

    ERIC Educational Resources Information Center

    Garton, Sue

    2014-01-01

    The introduction of languages, especially English, into the primary curriculum around the world has been one of the major language-in-education policy developments in recent years. In countries where English has been compulsory for a number of years, the question arises as to what extent the numerous and well-documented challenges faced by the…

  6. Sign Language: An Effective Strategy to Reduce the Gap between English Language Learners Native Language and English

    ERIC Educational Resources Information Center

    Nicholson, Sheryl; Graves, Emily

    2010-01-01

    Linguistic diversity provides even greater challenges for our educational system. English Language Learners (ELLs) are a diverse population of students who are learning English in school. They come from numerous cultural and economic backgrounds, and live throughout the country. The task of the classroom teacher is to find a way to reach these…

  7. East Europe Report.

    DTIC Science & Technology

    1986-06-25

    nuclear disaster will be averted, that peace can be rescued. We think that the initiatives of the governments of numerous nonaligned and neutral...we recently declared at the 135h BCP Congress, "for us, communists, the prevention of nuclear disaster and the preservation of universal peace is a...introduced against several Eastern European countries, including Hungary. Answer: I must be admitted that the Chernobyl nuclear disaster caused

  8. How Does Research Evaluation Impact Educational Research? Exploring Intended and Unintended Consequences of Research Assessment in the United Kingdom, 1986-2014

    ERIC Educational Resources Information Center

    Marques, Marcelo; Powell, Justin J. W.; Zapp, Mike; Biesta, Gert

    2017-01-01

    Research evaluation systems in many countries aim to improve the quality of higher education. Among the first of such systems, the UK's Research Assessment Exercise (RAE) dating from 1986 is now the Research Excellence Framework (REF). Highly institutionalised, it transforms research to be more accountable. While numerous studies describe the…

  9. Distance Education and Women Empowerment: The Women Who Dared at Distance Learning Institute

    ERIC Educational Resources Information Center

    Okunuga, A. O.

    2011-01-01

    In the past, the African female child had always been denied formal education due to various cultural and social prejudices. Distance education has been employed by numerous women, who had earlier thus been deprived, to bridge the educational gap between males and females in the country. These are mature females, of which the majority (54%) are…

  10. Against All Odds: Socio-Cultural Influence on Nontraditional International Learners Pursuing Higher Education in the United States

    ERIC Educational Resources Information Center

    Hunter-Johnson, Yvonne

    2016-01-01

    The decision to migrate to a foreign country with an unfamiliar educational system to pursue higher education as a nontraditional adult learner is a decision that is not taken frivolously. Despite the motivation and excitement coupled with such a journey, there are numerous unforeseen accompanying challenges from a socio-cultural perspective that…

  11. Building Better Courses: Examining the Content Validity of the iNACOL National Standards for Quality Online Courses

    ERIC Educational Resources Information Center

    Adelstein, David; Barbour, Michael

    2016-01-01

    In 2011, the International Association for K-12 Online Learning released the second iteration of the "National Standards for Quality Online Courses." These standards have been used by numerous institutions and states around the country to help design and create K-12 online courses. However, there has been no reported research on the…

  12. Identifying Tensions around Gender-Responsive Curriculum Practices in Science Teacher Education in Zimbabwe: An Activity Theory Analysis

    ERIC Educational Resources Information Center

    Chikunda, Charles

    2014-01-01

    The physical sciences, mathematics and technology subjects in Zimbabwe, like in most other African countries, are still male dominated. This is despite numerous efforts over the years directed towards gender equality in these disciplines. Many studies point at teacher education as not doing enough to assist future teachers in these disciplines…

  13. Distribution and occupancy of introduced species: a baseline inventory from Phase 3 plots across the country

    Treesearch

    Bethany K. Schulz; W. Keith Moser

    2012-01-01

    Invasive plant species have significant negative impacts in many ecosystems and are found in many forests around the world. Although not all introduced species become invasive, there are numerous examples of species escaping cultivation and invading natural ecosystems years or even decades after their initial introduction. Regional distributions of invasive species are...

  14. The Decline in Sexual Assaults in Men's Prisons in New South Wales: A "Systems" Approach

    ERIC Educational Resources Information Center

    Yap, Lorraine; Richters, Juliet; Butler, Tony; Schneider, Karen; Grant, Luke; Donovan, Basil

    2011-01-01

    Male prison rape and sexual assaults remains a serious and sensitive issue in many countries. Human rights groups claim that sexual assaults among male prisoners have reached pandemic proportions and need to be stopped. Researchers for many years have studied the causes of male sexual assault in prison and offered numerous recommendations on its…

  15. Walking a New Path of Life: Learning Tours, "Agroforestry" and the Transformation of the Village of Bann Na Isarn, Thailand

    ERIC Educational Resources Information Center

    Thacheen, Piyaporn; Lauzon, Allan C.

    2006-01-01

    Rural areas in both developed and developing countries are being increasingly marginalized through structural changes. Furthermore, the disinvestment in state-provided supports and services means that rural people are left to their own devices to cope with these changes. Numerous authors argue that the most effective way of dealing with these…

  16. From Mangos to Manufacturing: Uneven Development and Its Impact on Social Well-Being in the Dominican Republic

    ERIC Educational Resources Information Center

    Pomeroy, Carlton; Jacob, Steve

    2004-01-01

    The International Monetary Fund (IMF) and the World Bank have been trying to help developing countries speed up economic growth in order to help eradicate poverty. In the last two decades these policies in the Dominican Republic have caused rapid and severe changes. Over the last two centuries Dominican culture has faced numerous challenges…

  17. Alternatives to evacuation during wildland fire: Exploring adaptive capacity in one Idaho community

    Treesearch

    Travis B. Paveglio; Matthew S. Caroll; Pamela J. Jakes

    2010-01-01

    The use of alternatives to evacuation during wildfire events continues to be an intensely debated strategy in the professional and policy circles of numerous fire-prone countries. The most recent chapter comes in response to the Black Saturday Fires in Australia, which has led to policy changes concerning alternatives to evacuation in both Australia and USA. This study...

  18. Carbon emissions-income relationships with structural breaks: the case of the Middle Eastern and North African countries.

    PubMed

    El Montasser, Ghassen; Ajmi, Ahdi Noomen; Nguyen, Duc Khuong

    2018-01-01

    This article revisits the carbon dioxide (CO 2 ) emissions-GDP causal relationships in the Middle Eastern and North African (MENA) countries by employing the Rossi (Economet Theor 21:962-990, 2005) instability-robust causality test. We show evidence of significant causality relationships for all considered countries within the instability context, whereas the standard Granger causality test fails to detect causal links in any direction, except for Egypt, Iran, and Morocco. An important policy implication resulting from this robust analysis is that the income is not affected by the cuts in the CO 2 emissions for only two MENA countries, the UAE and Syria.

  19. A Causal Inference Analysis of the Effect of Wildland Fire ...

    EPA Pesticide Factsheets

    Wildfire smoke is a major contributor to ambient air pollution levels. In this talk, we develop a spatio-temporal model to estimate the contribution of fire smoke to overall air pollution in different regions of the country. We combine numerical model output with observational data within a causal inference framework. Our methods account for aggregation and potential bias of the numerical model simulation, and address uncertainty in the causal estimates. We apply the proposed method to estimation of ozone and fine particulate matter from wildland fires and the impact on health burden assessment. We develop a causal inference framework to assess contributions of fire to ambient PM in the presence of spatial interference.

  20. Global migration and health: ecofeminist perspectives.

    PubMed

    McGuire, S

    1998-12-01

    Global migration is occurring at an unprecedented rate. The phenomenon of migration is complex and poorly understood by most people in countries who host immigrants. People migrate for numerous reasons related to social, economic, political, cultural, and physical environmental conditions formed by historical antecedents. Migrating people, especially vulnerable women and children, are exposed to numerous health hazards, a situation calling for a response from nursing. To respond effectively nursing needs knowledge development of global migration and health that includes the precursors to migration in addition to the postmigration experience where nurses encounter immigrants. Ecofeminist perspectives allowing for reflection on historical determinants and interlocking socioeconomic, political, and environmental conditions are used as a prism to examine global migration and health.

  1. Comparison between firing tests and numerical simulation of vortex shedding in a 2-D test solid motor

    NASA Astrophysics Data System (ADS)

    Lupoglazoff, N.; Vuillot, F.

    Some comparisons between firing tests and numerical simulations of vortex shedding via a simple test case called 'C1experimental' are presented. These experiments are performed to validate further numerical simulations, as well as to serve as a tool for facilitating interpretation. At ignition time, spectra of pressure are more complex: it is the effect of vortex pairings. For 6.5-mm burnt, the second longitudinal mode dominates. For 8-mm burnt, the first longitudinal mode dominates. For 11.5-mm burnt, there is only the first longitudinal mode, with a slight shift of the frequency value. Tables are presented which give the pressure oscillation amplitudes of 'C1experimental' with operating pressures, and these amplitudes relative to the corresponding operating pressure.

  2. Numerical simulation of flood barriers

    NASA Astrophysics Data System (ADS)

    Srb, Pavel; Petrů, Michal; Kulhavý, Petr

    This paper deals with testing and numerical simulating of flood barriers. The Czech Republic has been hit by several very devastating floods in past years. These floods caused several dozens of causalities and property damage reached billions of Euros. The development of flood measures is very important, especially for the reduction the number of casualties and the amount of property damage. The aim of flood control measures is the detention of water outside populated areas and drainage of water from populated areas as soon as possible. For new flood barrier design it is very important to know its behaviour in case of a real flood. During the development of the barrier several standardized tests have to be carried out. Based on the results from these tests numerical simulation was compiled using Abaqus software and some analyses were carried out. Based on these numerical simulations it will be possible to predict the behaviour of barriers and thus improve their design.

  3. Current use and acceptability of novel diagnostic tests for active tuberculosis: a worldwide survey

    PubMed Central

    Amicosante, Massimo; D’Ambrosio, Lia; Munoz, Marcela; Mello, Fernanda Carvalho de Queiroz; Tebruegge, Marc; Chegou, Novel Njweipi; Seghrouchni, Fouad; Centis, Rosella; Goletti, Delia; Bothamley, Graham; Migliori, Giovanni Battista

    2017-01-01

    ABSTRACT Objective: To determine the current use and potential acceptance (by tuberculosis experts worldwide) of novel rapid tests for the diagnosis of tuberculosis that are in line with World Health Organization target product profiles. Methods: A multilingual survey was disseminated online between July and November of 2016. Results: A total of 723 individuals from 114 countries responded to the survey. Smear microscopy was the most commonly used rapid tuberculosis test (available to 90.9% of the respondents), followed by molecular assays (available to 70.7%). Only a small proportion of the respondents in middle- and low-income countries had access to interferon-gamma-release assays. Serological and lateral flow immunoassays were used by more than a quarter (25.4%) of the respondents. Among the respondents who had access to molecular tests, 46.7% were using the Xpert assay overall, that proportion being higher in lower middle-income countries (55.6%) and low-income countries (76.6%). The data also suggest that there was some alignment of pricing for molecular assays. Respondents stated they would accept novel rapid tuberculosis tests if available, including molecular assays (acceptable to 86.0%) or biomarker-based serological assays (acceptable to 81.7%). Simple biomarker-based assays were more commonly deemed acceptable in middle- and low-income countries. Conclusions: Second-generation molecular assays have become more widely available in high- and low-resource settings. However, the development of novel rapid tuberculosis tests continues to be considered important by tuberculosis experts. Our data also underscore the need for additional training and education of end users. PMID:29160384

  4. Current use and acceptability of novel diagnostic tests for active tuberculosis: a worldwide survey.

    PubMed

    Amicosante, Massimo; D'Ambrosio, Lia; Munoz, Marcela; Mello, Fernanda Carvalho de Queiroz; Tebruegge, Marc; Chegou, Novel Njweipi; Seghrouchni, Fouad; Centis, Rosella; Goletti, Delia; Bothamley, Graham; Migliori, Giovanni Battista

    2017-01-01

    To determine the current use and potential acceptance (by tuberculosis experts worldwide) of novel rapid tests for the diagnosis of tuberculosis that are in line with World Health Organization target product profiles. A multilingual survey was disseminated online between July and November of 2016. A total of 723 individuals from 114 countries responded to the survey. Smear microscopy was the most commonly used rapid tuberculosis test (available to 90.9% of the respondents), followed by molecular assays (available to 70.7%). Only a small proportion of the respondents in middle- and low-income countries had access to interferon-gamma-release assays. Serological and lateral flow immunoassays were used by more than a quarter (25.4%) of the respondents. Among the respondents who had access to molecular tests, 46.7% were using the Xpert assay overall, that proportion being higher in lower middle-income countries (55.6%) and low-income countries (76.6%). The data also suggest that there was some alignment of pricing for molecular assays. Respondents stated they would accept novel rapid tuberculosis tests if available, including molecular assays (acceptable to 86.0%) or biomarker-based serological assays (acceptable to 81.7%). Simple biomarker-based assays were more commonly deemed acceptable in middle- and low-income countries. Second-generation molecular assays have become more widely available in high- and low-resource settings. However, the development of novel rapid tuberculosis tests continues to be considered important by tuberculosis experts. Our data also underscore the need for additional training and education of end users.

  5. [World population growth and the food supply].

    PubMed

    Huang, Y

    1982-07-29

    The general trend in the last several hundred years has been that the speed of growth in the food supply exceeds the speed of the population growth. For the time being, 2 major problems still exist. The 1st problem is that food production is still influenced by natural conditions. For example, abnormal weather conditions may cause regional food shortages. The 2nd problem is the imbalance of food consumption by the world population. This phenomenon exists between different social classes as well as between developed and developing countries. According to statistics released by the World Bank, 1 billion suffer from malnutrition today and most of them are in developing countries. In developed countries, about half of their increase in the food supply is for feed grains, and those countries follow the policy of reducing farm land for the purpose of maintaing stabl e grain prices. Up to the present time, grain prices have been unstable, and this has become a rather heavy economic burden for numerous developing countries. Many developing countries are trying to increase grain production by increasing their arable land and promoting their cultivating techniques. However, these countries are facing the problems of finding and adequate water supply, fertilizer, and pesticides. In addition, a rapid population growth in these countries has offset their endeavors in agriculture. In recent years, these counties have realized the necessity of birth control. The world population growth rate has decreased from 2% to about 1.7% in 1981. Birth control and an increase in the food supply will bring new hope to the world's problems of overpopulation and food supply.

  6. Hybrid test on building structures using electrodynamic fatigue test machine

    NASA Astrophysics Data System (ADS)

    Xu, Zhao-Dong; Wang, Kai-Yang; Guo, Ying-Qing; Wu, Min-Dong; Xu, Meng

    2017-01-01

    Hybrid simulation is an advanced structural dynamic experimental method that combines experimental physical models with analytical numerical models. It has increasingly been recognised as a powerful methodology to evaluate structural nonlinear components and systems under realistic operating conditions. One of the barriers for this advanced testing is the lack of flexible software for hybrid simulation using heterogeneous experimental equipment. In this study, an electrodynamic fatigue test machine is made and a MATLAB program is developed for hybrid simulation. Compared with the servo-hydraulic system, electrodynamic fatigue test machine has the advantages of small volume, easy operation and fast response. A hybrid simulation is conducted to verify the flexibility and capability of the whole system whose experimental substructure is one spring brace and numerical substructure is a two-storey steel frame structure. Experimental and numerical results show the feasibility and applicability of the whole system.

  7. Numerical analysis and experimental verification of elastomer bending process with different material models

    NASA Astrophysics Data System (ADS)

    Kut, Stanislaw; Ryzinska, Grazyna; Niedzialek, Bernadetta

    2016-01-01

    The article presents the results of tests in order to verifying the effectiveness of the nine selected elastomeric material models (Neo-Hookean, Mooney with two and three constants, Signorini, Yeoh, Ogden, Arruda-Boyce, Gent and Marlow), which the material constants were determined in one material test - the uniaxial tension testing. The convergence assessment of nine analyzed models were made on the basis of their performance from an experimental bending test of the elastomer samples from the results of numerical calculations FEM for each material models. To calculate the material constants for the analyzed materials, a model has been generated by the stressstrain characteristics created as a result of experimental uniaxial tensile test with elastomeric dumbbell samples, taking into account the parameters received in its 18th cycle. Using such a calculated material constants numerical simulation of the bending process of a elastomeric, parallelepipedic sampleswere carried out using MARC / Mentat program.

  8. Allergic Contact Dermatitis to Ophthalmic Medications: Relevant Allergens and Alternative Testing Methods.

    PubMed

    Grey, Katherine R; Warshaw, Erin M

    Allergic contact dermatitis is an important cause of periorbital dermatitis. Topical ophthalmic agents are relevant sensitizers. Contact dermatitis to ophthalmic medications can be challenging to diagnose and manage given the numerous possible offending agents, including both active and inactive ingredients. Furthermore, a substantial body of literature reports false-negative patch test results to ophthalmic agents. Subsequently, numerous alternative testing methods have been described. This review outlines the periorbital manifestations, causative agents, and alternative testing methods of allergic contact dermatitis to ophthalmic medications.

  9. Experiences using and organizing HIV self-testing.

    PubMed

    Qin, Yilu; Han, Larry; Babbitt, Andrew; Walker, Jennifer S; Liu, Fengying; Thirumurthy, Harsha; Tang, Weiming; Tucker, Joseph D

    2018-01-28

    HIV self-testing (HIVST) is now officially recommended by the WHO, yet much of HIVST evidence to date has focused on quantitative data and hypothetical concerns. Effective scale-up of HIVST in diverse local contexts requires qualitative data from experiences using and organizing HIVST. This qualitative systematic review aims to appraise and synthesize research evidence on experiences using and organizing HIVST. We conducted a systematic search of seven primary literature databases, four gray literature sources, and reference lists reporting qualitative evidence on HIVST. Data extraction and thematic analysis were used to synthesize findings. Quality of studies was assessed using the Critical Appraisal Skills Programme tool. Confidence in review findings was evaluated using the Confidence in the Evidence from Reviews of Qualitative Research approach. The review protocol was registered (CRD42015027607). From 1266 potential articles, we included 18. Four studies were conducted in low-income countries, three in middle-income countries, 10 in high-income countries, and one in multiple countries. Generally, HIVST increased capacity to reach priority populations and expanded opportunities for service delivery. Self-testing was preferred to facility-based testing due to increased convenience and confidentiality, especially among stigmatized populations. HIVST decreased test-associated stigma compared with facility-based testing. HIVST generally empowered people because it provided greater control over individual testing needs. At the same time, HIVST rarely allowed husbands to coerce their wives to test. This review suggests that HIVST should be offered as an additional HIV testing option to expand testing and empower testers. Adapting national policies to incorporate HIVST will be necessary to guide scale-up.

  10. External quality assurance for HIV point-of-care testing in Africa: A collaborative country-partner approach to strengthen diagnostic services

    PubMed Central

    2016-01-01

    It is important to consider the role of diagnostics and the critical need for quality diagnostics services in resource-limited settings. Accurate diagnostic tests play a key role in patient management and the prevention and control of most infectious diseases. As countries plan for implementation of HIV early infant diagnosis and viral load point-of-care testing, the London School of Hygiene & Tropical Medicine has worked with countries and partners with an interest in external quality assurance to support quality point-of-care testing on the continent. Through a series of collaborative consultations and workshops, the London School of Hygiene & Tropical Medicine has gathered lessons learned, tools, and resources and developed quality assurance models that will support point-of-care testing. The London School of Hygiene & Tropical Medicine is committed to the continued advancement of laboratory diagnostics in Africa and quality laboratory services and point-of-care testing. PMID:28879132

  11. Implementing services for Early Infant Diagnosis (EID) of HIV: a comparative descriptive analysis of national programs in four countries.

    PubMed

    Chatterjee, Anirban; Tripathi, Sangeeta; Gass, Robert; Hamunime, Ndapewa; Panha, Sok; Kiyaga, Charles; Wade, Abdoulaye; Barnhart, Matthew; Luo, Chewe; Ekpini, Rene

    2011-07-13

    There is a significant increase in survival for HIV-infected children who have early access to diagnosis and treatment. The goal of this multi-country review was to examine when and where HIV-exposed infants and children are being diagnosed, and whether the EID service is being maximally utilized to improve health outcomes for HIV-exposed children. In four countries across Africa and Asia existing documents and data were reviewed and key informant interviews were conducted. EID testing data was gathered from the central testing laboratories and was then complemented by health facility level data extraction which took place using a standardized and validated questionnaire In the four countries reviewed from 2006 to 2009 EID sample volumes rose dramatically to an average of >100 samples per quarter in Cambodia and Senegal, >7,000 samples per quarter in Uganda, and >2,000 samples per quarter in Namibia. Geographic coverage of sites also rapidly expanded to 525 sites in Uganda, 205 in Namibia, 48 in Senegal, and 26 in Cambodia in 2009. However, only a small proportion of testing was done at lower-level health facilities: in Uganda Health Center IIs and IIIs comprised 47% of the EID collection sites, but only 11% of the total tests, and in Namibia 15% of EID sites collected >93% of all samples. In all countries except for Namibia, more than 50% of the EID testing was done after 2 months of age. Few sites had robust referral mechanisms between EID and ART. In a sub-sample of children, we noted significant attrition of infants along the continuum of care post testing. Only 22% (Senegal), 37% (Uganda), and 38% (Cambodia) of infants testing positive by PCR were subsequently initiated onto treatment. In Namibia, which had almost universal EID coverage, more than 70% of PCR-positive infants initiated ART in 2008. While EID testing has expanded dramatically, a large proportion of PCR- positive infants are initiated on treatment. As EID services continue to scale-up, more programmatic attention and support is needed to retain HIV-exposed infants in care and ensure that those testing positive initiate treatment in a timely manner. Namibia's experience demonstrates that it is feasible for a rural, low-income country to achieve high national coverage of infant testing and treatment.

  12. Test anxiety in Indian children: a cross-cultural perspective.

    PubMed

    Bodas, Jaee; Ollendick, Thomas H; Sovani, Anuradha V

    2008-10-01

    The present investigation examined test anxiety in Indian children from a cross-cultural perspective. Test anxiety has been studied extensively in western countries but much less so in eastern countries. Furthermore, the cross-cultural research conducted in eastern countries possesses significant limitations and continues to possess a western bias. The present research attempted to advance cross-cultural research on test anxiety by adopting Berry's imposed etic-emic-derived etic methodology. Participants included 231 schoolchildren. Qualitative data were collected to examine culture-specific variables (emic considerations) using structured focus groups and open-ended questions. Next, quantitative data were collected using translated and adapted versions of Spielberger's Test Anxiety Inventory and the FRIEDBEN Test Anxiety Scale. Qualitative data indicated culture-specific elements of test anxiety in Indian youth, including the high stakes associated with exam performance and future schooling as well as the role of somatization and social derogation in the phenomenological experience of test anxiety. Although quantitative findings failed to confirm the importance of high-stakes environments on test anxiety, the importance of somatization and social derogation was substantiated. Ongoing desensitization to test anxiety and enhanced coping responses were proposed as possible explanations for the obtained relations.

  13. The role of food-security solutions in the protection of natural resources and environment of developing countries.

    PubMed

    Lashgarara, Farhad; Mirdamadi, Seyyed Mehdi; Hosseini, Seyyed Jamal Farajollah; Chizari, Mohammad

    2008-10-01

    The majority of the countries of the world, especially developing countries, face environmental problems. Limitations of basic resources (water and soil) and population growth have been the cause of these environmental problems that countries are confronted with. Developing countries have numerous problems, including destruction of forests, vegetable and animal species, and pollution of the environment. Damage to natural resources and the environment can influence the food-security situation. One of the main millennium development goals (MDGs) is protection of the environment and people's health. This cannot obtained unless there is ensured food security. Food security has been defined as a situation when all people, at all times, have physical and economic access to sufficient, safe, and nutritious food needed to maintain a healthy and active life. At the same time, with ensured food security, we can hope to protect the natural resources and environment. The methodology used is descriptive-analytical, and its main purpose is determining the importance and role of food-security solutions in the reduction of environmental hazards and improvement of natural resources and the environmental situation in developing countries. Therefore, some of the most important food-security solutions that can play an important role in this relation were discussed, including conventional research-based technology, biotechnology, information and communication technologies (ICTs), alternative energy sources, and food irradiation.

  14. Socioeconomic inequalities in childhood overweight: heterogeneity across five countries in the WHO European Childhood Obesity Surveillance Initiative (COSI-2008).

    PubMed

    Lissner, L; Wijnhoven, T M A; Mehlig, K; Sjöberg, A; Kunesova, M; Yngve, A; Petrauskiene, A; Duleva, V; Rito, A I; Breda, J

    2016-05-01

    Excess risk of childhood overweight and obesity occurring in socioeconomically disadvantaged families has been demonstrated in numerous studies from high-income regions, including Europe. It is well known that socioeconomic characteristics such as parental education, income and occupation are etiologically relevant to childhood obesity. However, in the pan-European setting, there is reason to believe that inequalities in childhood weight status may vary among countries as a function of differing degrees of socioeconomic development and equity. In this cross-sectional study, we have examined socioeconomic differences in childhood obesity in different parts of the European region using nationally representative data from Bulgaria, the Czech Republic, Lithuania, Portugal and Sweden that were collected in 2008 during the first round of the World Health Organization (WHO) European Childhood Obesity Surveillance Initiative. Heterogeneity in the association between parental socioeconomic indicators and childhood overweight or obesity was clearly observed across the five countries studied. Positive as well as negative associations were observed between parental socioeconomic indicators and childhood overweight, with statistically significant interactions between country and parental indicators. These findings have public health implications for the WHO European Region and underscore the necessity to continue documenting socioeconomic inequalities in obesity in all countries through international surveillance efforts in countries with diverse geographic, social and economic environments. This is a prerequisite for universal as well as targeted preventive actions.

  15. Experimental and numerical study of drill bit drop tests on Kuru granite.

    PubMed

    Fourmeau, Marion; Kane, Alexandre; Hokka, Mikko

    2017-01-28

    This paper presents an experimental and numerical study of Kuru grey granite impacted with a seven-buttons drill bit mounted on an instrumented drop test machine. The force versus displacement curves during the impact, so-called bit-rock interaction (BRI) curves, were obtained using strain gauge measurements for two levels of impact energy. Moreover, the volume of removed rock after each drop test was evaluated by stereo-lithography (three-dimensional surface reconstruction). A modified version of the Holmquist-Johnson-Cook (MHJC) material model was calibrated using Kuru granite test results available from the literature. Numerical simulations of the single drop tests were carried out using the MHJC model available in the LS-DYNA explicit finite-element solver. The influence of the impact energy and additional confining pressure on the BRI curves and the volume of the removed rock is discussed. In addition, the influence of the rock surface shape before impact was evaluated using two different mesh geometries: a flat surface and a hyperbolic surface. The experimental and numerical results are compared and discussed in terms of drilling efficiency through the mechanical specific energy.This article is part of the themed issue 'Experimental testing and modelling of brittle materials at high strain rates'. © 2016 The Author(s).

  16. Experimental and numerical study of drill bit drop tests on Kuru granite

    PubMed Central

    Kane, Alexandre; Hokka, Mikko

    2017-01-01

    This paper presents an experimental and numerical study of Kuru grey granite impacted with a seven-buttons drill bit mounted on an instrumented drop test machine. The force versus displacement curves during the impact, so-called bit–rock interaction (BRI) curves, were obtained using strain gauge measurements for two levels of impact energy. Moreover, the volume of removed rock after each drop test was evaluated by stereo-lithography (three-dimensional surface reconstruction). A modified version of the Holmquist–Johnson–Cook (MHJC) material model was calibrated using Kuru granite test results available from the literature. Numerical simulations of the single drop tests were carried out using the MHJC model available in the LS-DYNA explicit finite-element solver. The influence of the impact energy and additional confining pressure on the BRI curves and the volume of the removed rock is discussed. In addition, the influence of the rock surface shape before impact was evaluated using two different mesh geometries: a flat surface and a hyperbolic surface. The experimental and numerical results are compared and discussed in terms of drilling efficiency through the mechanical specific energy. This article is part of the themed issue ‘Experimental testing and modelling of brittle materials at high strain rates’. PMID:27956511

  17. The effect of information about false negative and false positive rates on people's attitudes towards colorectal cancer screening using faecal occult blood testing (FOBt).

    PubMed

    Miles, Anne; Rodrigues, Vania; Sevdalis, Nick

    2013-11-01

    To examine the impact of numeric risk information about false negative (FN) and false positive (FP) rates in faecal occult blood testing (FOBt) on attitudes towards screening. 95 people aged 45-59, living in England, read 6 hypothetical vignettes presented online about the use of FOB testing to detect bowel cancer, in which information about FN and FP rates was systematically varied. Both verbal and numeric FN risk information reduced people's interest in screening compared with no FN information. Numeric FN risk information reduced people's perceptions of screening effectiveness and lowered perceived trust in the results of screening compared with both verbal FN information and no FN information. FP information did not affect attitudes towards FOB testing. There was limited evidence that FN information reduced interest and perceptions of screening effectiveness more in educated groups. Numeric FN risk information decreased people's perceptions of screening effectiveness and trust in the results of screening but did not affect people's interest in screening anymore than verbal FN risk information. Numeric FN information could be added to patient information without affecting interest in screening, although this needs to be replicated in a larger, more representative sample. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

  18. Can Norms Developed in One Country Be Applicable to Children of Another Country?

    ERIC Educational Resources Information Center

    Lam, Hazel Mei Yung

    2008-01-01

    The primary aim this study was to investigate whether a gross motor proficiency norm developed in one country could be applied to young children in another country. The secondary aim of the study was to assess the gross motor proficiency of Hong Kong preschoolers aged five years. The Bruininks-Oseretsky Test of Motor Proficiency (BOTMP) (subtests…

  19. Experiments and Dynamic Finite Element Analysis of a Wire-Rope Rockfall Protective Fence

    NASA Astrophysics Data System (ADS)

    Tran, Phuc Van; Maegawa, Koji; Fukada, Saiji

    2013-09-01

    The imperative need to protect structures in mountainous areas against rockfall has led to the development of various protection methods. This study introduces a new type of rockfall protection fence made of posts, wire ropes, wire netting and energy absorbers. The performance of this rock fence was verified in both experiments and dynamic finite element analysis. In collision tests, a reinforced-concrete block rolled down a natural slope and struck the rock fence at the end of the slope. A specialized system of measuring instruments was employed to accurately measure the acceleration of the block without cable connection. In particular, the performance of two energy absorbers, which contribute also to preventing wire ropes from breaking, was investigated to determine the best energy absorber. In numerical simulation, a commercial finite element code having explicit dynamic capabilities was employed to create models of the two full-scale tests. To facilitate simulation, certain simplifying assumptions for mechanical data of each individual component of the rock fence and geometrical data of the model were adopted. Good agreement between numerical simulation and experimental data validated the numerical simulation. Furthermore, the results of numerical simulation helped highlight limitations of the testing method. The results of numerical simulation thus provide a deeper understanding of the structural behavior of individual components of the rock fence during rockfall impact. More importantly, numerical simulations can be used not only as supplements to or substitutes for full-scale tests but also in parametric study and design.

  20. Analysis and testing of numerical formulas for the initial value problem

    NASA Technical Reports Server (NTRS)

    Brown, R. L.; Kovach, K. R.; Popyack, J. L.

    1980-01-01

    Three computer programs for evaluating and testing numerical integration formulas used with fixed stepsize programs to solve initial value systems of ordinary differential equations are described. A program written in PASCAL SERIES, takes as input the differential equations and produces a FORTRAN subroutine for the derivatives of the system and for computing the actual solution through recursive power series techniques. Both of these are used by STAN, a FORTRAN program that interactively displays a discrete analog of the Liapunov stability region of any two dimensional subspace of the system. The derivatives may be used by CLMP, a FORTRAN program, to test the fixed stepsize formula against a good numerical result and interactively display the solutions.

  1. Structural and numerical chromosome aberration inducers in liver micronucleus test in rats with partial hepatectomy.

    PubMed

    Itoh, Satoru; Hattori, Chiharu; Nagata, Mayumi; Sanbuissho, Atsushi

    2012-08-30

    The liver micronucleus test is an important method to detect pro-mutagens such as active metabolites not reaching bone marrow due to their short lifespan. We have already reported that dosing of the test compound after partial hepatectomy (PH) is essential to detect genotoxicity of numerical chromosome aberration inducers in mice [Mutat. Res. 632 (2007) 89-98]. In naive animals, the proportion of binucleated cells in rats is less than half of that in mice, which suggests a species difference in the response to chromosome aberration inducers. In the present study, we investigated the responses to structural and numerical chromosome aberration inducers in the rat liver micronucleus test. Two structural chromosome aberretion inducers (diethylnitrosamine and 1,2-dimethylhydrazine) and two numerical chromosome aberration inducers (colchicine and carbendazim) were used in the present study. PH was performed a day before or after the dosing of the test compound in 8-week old male F344 rats and hepatocytes were isolated 4 days after the PH. As a result, diethylnitrosamine and 1,2-dimethylhydrazine, structural chromosome aberration inducers, exhibited significant increase in the incidence of micronucleated hepatocyte (MNH) when given either before and after PH. Colchicine and carbendazim, numerical chromosome aberration inducers, did not result in any toxicologically significant increase in MNH frequency when given before PH, while they exhibited MNH induction when given after PH. It is confirmed that dosing after PH is essential in order to detect genotoxicity of numerical chromosome aberration inducers in rats as well as in mice. Regarding the species difference, a different temporal response to colchicine was identified. Colchicine increased the incidence of MNH 4 days after PH in rats, although such induction in mice was observed 8-10 days after PH. Copyright © 2012 Elsevier B.V. All rights reserved.

  2. Radiation doses to local populations near nuclear weapons test sites worldwide.

    PubMed

    Simon, Steven L; Bouville, André

    2002-05-01

    Nuclear weapons testing was conducted in the atmosphere at numerous sites worldwide between 1946 and 1980, which resulted in exposures to local populations as a consequence of fallout of radioactive debris. The nuclear tests were conducted by five nations (United States, Soviet Union, United Kingdom, France, and China) primarily at 16 sites. The 16 testing sites, located in nine different countries on five continents (plus Oceania) contributed nearly all of the radioactive materials released to the environment by atmospheric testing; only small amounts were released at a fewother minor testing sites. The 16 sites discussed here are Nevada Test Site, USA (North American continent), Bikini and Enewetak, Marshall Islands (Oceania); Johnston Island, USA (Oceania), Christmas and Malden Island, Kiribati (Oceania); Emu Field, Maralinga, and Monte Bello Islands, Australia (Australian continent); Mururoa and Fangataufa, French Polynesia (Oceania), Reggane, Algeria (Africa), Novaya Zemlya and Kapustin Yar, Russia (Europe), Semipalatinsk, Kazakhstan (Asia), and Lop Nor, China (Asia). There were large differences in the numbers of tests conducted at each location and in the total explosive yields. Those factors, as well as differences in population density, lifestyle, environment, and climate at each site, led to large differences in the doses received by local populations. In general, the tests conducted earliest led to the highest individual and population exposures, although the amount of information available for a few of these sites is insufficient to provide any detailed evaluation of radiation exposures. The most comprehensive information for any site is for the Nevada Test Site. The disparities in available information add difficulty to determining the radiation exposures of local populations at each site. It is the goal of this paper to summarize the available information on external and internal doses received by the public living in the regions near each of the mentioned nuclear test sites as a consequence of local fallout deposition.

  3. Malaria rapid diagnostic tests in tropical climates: the need for a cool chain.

    PubMed

    Jorgensen, Pernille; Chanthap, Lon; Rebueno, Antero; Tsuyuoka, Reiko; Bell, David

    2006-05-01

    Malaria control programs in endemic countries increasingly rely on early case detection and treatment at village level. The rapid diagnostic tests (RDTs) and accompanying drugs on which the success of these programs depends deteriorate to varying degrees at high temperatures. To assess the ability of health systems to maintain RDTs within manufacturers' specifications, we monitored temperatures in the delivery chain from manufacturer through to the village health worker in Cambodia and the Philippines. In both countries, storage temperatures regularly exceeded those recommended for most RDTs intended for field use, whereas temperatures during transport greatly exceeded the lower and upper limits. These results emphasize the need for good logistical planning during the introduction of point-of-care tests in tropical countries and the importance of considering the stability of diagnostic tests during procurement.

  4. Math anxiety, self-efficacy, and ability in British undergraduate nursing students.

    PubMed

    McMullan, Miriam; Jones, Ray; Lea, Susan

    2012-04-01

    Nurses need to be able to make drug calculations competently. In this study, involving 229 second year British nursing students, we explored the influence of mathematics anxiety, self-efficacy, and numerical ability on drug calculation ability and determined which factors would best predict this skill. Strong significant relationships (p < .001) existed between anxiety, self-efficacy, and ability. Students who failed the numerical and/or drug calculation ability tests were more anxious (p < .001) and less confident (p ≤ .002) in performing calculations than those who passed. Numerical ability made the strongest unique contribution in predicting drug calculation ability (beta = 0.50, p < .001) followed by drug calculation self-efficacy (beta = 0.16, p = .04). Early testing is recommended for basic numerical skills. Faculty are advised to refresh students' numerical skills before introducing drug calculations. Copyright © 2012 Wiley Periodicals, Inc.

  5. Slow Crack Growth Analysis of Advanced Structural Ceramics Under Combined Loading Conditions: Damage Assessment in Life Prediction Testing

    NASA Technical Reports Server (NTRS)

    Choi, Sung R.; Gyekenyesi, John P.

    2000-01-01

    Slow crack growth analysis was performed with three different loading histories including constant stress-rate/constant stress-rate testing (Case 1 loading), constant stress/constant stress-rate testing (Case 2 loading), and cyclic stress/constant stress-rate testing (Case 2 loading). Strength degradation due to slow crack growth and/or damage accumulation was determined numerically as a function of percentage of interruption time between the two loading sequences for a given loading history. The numerical solutions were examined with the experimental data determined at elevated temperatures using four different advanced ceramic materials, two silicon nitrides, one silicon carbide and one alumina for the Case 1 loading history, and alumina for the Case 3 loading history. The numerical solutions were in reasonable agreement with the experimental data, indicating that notwithstanding some degree of creep deformation presented for some test materials slow crack growth was a governing mechanism associated with failure for all the test materials.

  6. Slow Crack Growth Analysis of Advanced Structural Ceramics Under Combined Loading Conditions: Damage Assessment in Life Prediction Testing

    NASA Technical Reports Server (NTRS)

    Choi, Sung R.; Gyekenyesi, John P.

    2000-01-01

    Slow crack growth analysis was performed with three different loading histories including constant stress-rate/constant stress-rate testing (Case I loading), constant stress/constant stress-rate testing (Case II loading), and cyclic stress/constant stress-rate testing (Case III loading). Strength degradation due to slow crack growth arid/or damage accumulation was determined numerically as a Function of percentage of interruption time between the two loading sequences for a given loading history. The numerical solutions were examined with the experimental data determined at elevated temperatures using four different advanced ceramic materials, two silicon nitrides, one silicon carbide and one alumina for the Case I loading history, and alumina for the Case II loading history. The numerical solutions were in reasonable agreement with the experimental data, indicating that notwithstanding some degree of creep deformation presented for some test materials slow crack growth was a governing mechanism associated with failure for all the test material&

  7. Abstract Spatial Reasoning as an Autistic Strength

    PubMed Central

    Stevenson, Jennifer L.; Gernsbacher, Morton Ann

    2013-01-01

    Autistic individuals typically excel on spatial tests that measure abstract reasoning, such as the Block Design subtest on intelligence test batteries and the Raven’s Progressive Matrices nonverbal test of intelligence. Such well-replicated findings suggest that abstract spatial processing is a relative and perhaps absolute strength of autistic individuals. However, previous studies have not systematically varied reasoning level – concrete vs. abstract – and test domain – spatial vs. numerical vs. verbal, which the current study did. Autistic participants (N = 72) and non-autistic participants (N = 72) completed a battery of 12 tests that varied by reasoning level (concrete vs. abstract) and domain (spatial vs. numerical vs. verbal). Autistic participants outperformed non-autistic participants on abstract spatial tests. Non-autistic participants did not outperform autistic participants on any of the three domains (spatial, numerical, and verbal) or at either of the two reasoning levels (concrete and abstract), suggesting similarity in abilities between autistic and non-autistic individuals, with abstract spatial reasoning as an autistic strength. PMID:23533615

  8. Association between Physical Fitness and Successful Aging in Taiwanese Older Adults.

    PubMed

    Lin, Pay-Shin; Hsieh, Chih-Chin; Cheng, Huey-Shinn; Tseng, Tsai-Jou; Su, Shin-Chang

    2016-01-01

    Population aging is escalating in numerous countries worldwide; among them is Taiwan, which will soon become an aged society. Thus, aging successfully is an increasing concern. One of the factors for achieving successful aging (SA) is maintaining high physical function. The purpose of this study was to determine the physical fitness factors associated with SA in Taiwanese older adults (OAs), because these factors are intervenable. Community-dwelling OAs aged more than 65 years and residing in Northern Taiwan were recruited in this study. They received a comprehensive geriatric assessment, which includes sociodemographic data, health conditions and behaviors, activities of daily living (ADL) and instrumental ADL (IADL) function, cognitive and depressive status, and quality of life. Physical fitness tests included the grip strength (GS), 30-second sit-to-stand (30s STS), timed up-and-go (TUG), functional reach (FR), one-leg standing, chair sit-and-reach, and reaction time (drop ruler) tests as well as the 6-minute walk test (6MWT). SA status was defined as follows: complete independence in performing ADL and IADL, satisfactory cognitive status (Mini-Mental State Examination ≥ 24), no depression (Geriatric Depression Scale < 5), and favorable social function (SF subscale ≥ 80 in SF-36). Adjusted multiple logistic regression analyses were performed. Among the total recruited OAs (n = 378), 100 (26.5%) met the aforementioned SA criteria. After adjustment for sociodemographic characteristics and health condition and behaviors, some physical fitness tests, namely GS, 30s STS, 6MWT, TUG, and FR tests, were significantly associated with SA individually, but not in the multivariate model. Among the physical fitness variables tested, cardiopulmonary endurance, mobility, muscle strength, and balance were significantly associated with SA in Taiwanese OAs. Early detection of deterioration in the identified functions and corresponding intervention is essential to ensuring SA.

  9. Association between Physical Fitness and Successful Aging in Taiwanese Older Adults

    PubMed Central

    Cheng, Huey-Shinn; Tseng, Tsai-Jou; Su, Shin-Chang

    2016-01-01

    Population aging is escalating in numerous countries worldwide; among them is Taiwan, which will soon become an aged society. Thus, aging successfully is an increasing concern. One of the factors for achieving successful aging (SA) is maintaining high physical function. The purpose of this study was to determine the physical fitness factors associated with SA in Taiwanese older adults (OAs), because these factors are intervenable. Community-dwelling OAs aged more than 65 years and residing in Northern Taiwan were recruited in this study. They received a comprehensive geriatric assessment, which includes sociodemographic data, health conditions and behaviors, activities of daily living (ADL) and instrumental ADL (IADL) function, cognitive and depressive status, and quality of life. Physical fitness tests included the grip strength (GS), 30-second sit-to-stand (30s STS), timed up-and-go (TUG), functional reach (FR), one-leg standing, chair sit-and-reach, and reaction time (drop ruler) tests as well as the 6-minute walk test (6MWT). SA status was defined as follows: complete independence in performing ADL and IADL, satisfactory cognitive status (Mini-Mental State Examination ≥ 24), no depression (Geriatric Depression Scale < 5), and favorable social function (SF subscale ≥ 80 in SF-36). Adjusted multiple logistic regression analyses were performed. Among the total recruited OAs (n = 378), 100 (26.5%) met the aforementioned SA criteria. After adjustment for sociodemographic characteristics and health condition and behaviors, some physical fitness tests, namely GS, 30s STS, 6MWT, TUG, and FR tests, were significantly associated with SA individually, but not in the multivariate model. Among the physical fitness variables tested, cardiopulmonary endurance, mobility, muscle strength, and balance were significantly associated with SA in Taiwanese OAs. Early detection of deterioration in the identified functions and corresponding intervention is essential to ensuring SA. PMID:26963614

  10. Successes and Short Comings in Four Years of an International External Quality Assurance Program for Animal Influenza Surveillance

    PubMed Central

    Spackman, Erica; Cardona, Carol; Muñoz-Aguayo, Jeannette; Fleming, Susan

    2016-01-01

    The US National institutes of Health-Centers of Excellence for Influenza Research and Surveillance is a research consortium that funds numerous labs worldwide to conduct influenza A surveillance in diverse animal species. There is no harmonization of testing procedures among these labs; therefore an external quality assurance (EQA) program was implemented to evaluate testing accuracy among labs in the program in 2012. Accurate detection of novel influenza A variants is crucial because of the broad host range and potentially high virulence of the virus in diverse species. Two molecular detection sample sets and 2 serology sample sets (one with avian origin isolates, and one with mammalian origin isolates each) were made available at approximately six month intervals. Participating labs tested the material in accordance with their own protocols. During a five year period a total of 41 labs from 23 countries ordered a total of 132 avian molecular, 121 mammalian molecular and 90 serology sample sets. Testing was completed by 111 individuals. Detection of type A influenza by RT-PCR was reliable with a pass rate (80% or greater agreement with expected results) of 86.6% for avian and 86.2% for mammalian origin isolates. However, identification of subtype by RT-PCR was relatively poor with 54.1% and 75.9% accuracy for avian and mammalian influenza isolates respectively. Serological testing had an overall pass rate of 86.9% and 22/23 labs used commercial ELISA kits. Based on the results of this EQA program six labs modified their procedures to improve accuracy and one lab identified an unknown equipment problem. These data represent the successful implementation of an international EQA program for an infectious disease; insights into the logistics and test design are also discussed. PMID:27788155

  11. Successes and Short Comings in Four Years of an International External Quality Assurance Program for Animal Influenza Surveillance.

    PubMed

    Spackman, Erica; Cardona, Carol; Muñoz-Aguayo, Jeannette; Fleming, Susan

    2016-01-01

    The US National institutes of Health-Centers of Excellence for Influenza Research and Surveillance is a research consortium that funds numerous labs worldwide to conduct influenza A surveillance in diverse animal species. There is no harmonization of testing procedures among these labs; therefore an external quality assurance (EQA) program was implemented to evaluate testing accuracy among labs in the program in 2012. Accurate detection of novel influenza A variants is crucial because of the broad host range and potentially high virulence of the virus in diverse species. Two molecular detection sample sets and 2 serology sample sets (one with avian origin isolates, and one with mammalian origin isolates each) were made available at approximately six month intervals. Participating labs tested the material in accordance with their own protocols. During a five year period a total of 41 labs from 23 countries ordered a total of 132 avian molecular, 121 mammalian molecular and 90 serology sample sets. Testing was completed by 111 individuals. Detection of type A influenza by RT-PCR was reliable with a pass rate (80% or greater agreement with expected results) of 86.6% for avian and 86.2% for mammalian origin isolates. However, identification of subtype by RT-PCR was relatively poor with 54.1% and 75.9% accuracy for avian and mammalian influenza isolates respectively. Serological testing had an overall pass rate of 86.9% and 22/23 labs used commercial ELISA kits. Based on the results of this EQA program six labs modified their procedures to improve accuracy and one lab identified an unknown equipment problem. These data represent the successful implementation of an international EQA program for an infectious disease; insights into the logistics and test design are also discussed.

  12. Towards a suite of test cases and a pycomodo library to assess and improve numerical methods in ocean models

    NASA Astrophysics Data System (ADS)

    Garnier, Valérie; Honnorat, Marc; Benshila, Rachid; Boutet, Martial; Cambon, Gildas; Chanut, Jérome; Couvelard, Xavier; Debreu, Laurent; Ducousso, Nicolas; Duhaut, Thomas; Dumas, Franck; Flavoni, Simona; Gouillon, Flavien; Lathuilière, Cyril; Le Boyer, Arnaud; Le Sommer, Julien; Lyard, Florent; Marsaleix, Patrick; Marchesiello, Patrick; Soufflet, Yves

    2016-04-01

    The COMODO group (http://www.comodo-ocean.fr) gathers developers of global and limited-area ocean models (NEMO, ROMS_AGRIF, S, MARS, HYCOM, S-TUGO) with the aim to address well-identified numerical issues. In order to evaluate existing models, to improve numerical approaches and methods or concept (such as effective resolution) to assess the behavior of numerical model in complex hydrodynamical regimes and to propose guidelines for the development of future ocean models, a benchmark suite that covers both idealized test cases dedicated to targeted properties of numerical schemes and more complex test case allowing the evaluation of the kernel coherence is proposed. The benchmark suite is built to study separately, then together, the main components of an ocean model : the continuity and momentum equations, the advection-diffusion of the tracers, the vertical coordinate design and the time stepping algorithms. The test cases are chosen for their simplicity of implementation (analytic initial conditions), for their capacity to focus on a (few) scheme or part of the kernel, for the availability of analytical solutions or accurate diagnoses and lastly to simulate a key oceanic processus in a controlled environment. Idealized test cases allow to verify properties of numerical schemes advection-diffusion of tracers, - upwelling, - lock exchange, - baroclinic vortex, - adiabatic motion along bathymetry, and to put into light numerical issues that remain undetected in realistic configurations - trajectory of barotropic vortex, - interaction current - topography. When complexity in the simulated dynamics grows up, - internal wave, - unstable baroclinic jet, the sharing of the same experimental designs by different existing models is useful to get a measure of the model sensitivity to numerical choices (Soufflet et al., 2016). Lastly, test cases help in understanding the submesoscale influence on the dynamics (Couvelard et al., 2015). Such a benchmark suite is an interesting bed to continue research in numerical approaches as well as an efficient tool to maintain any oceanic code and assure the users a stamped model in a certain range of hydrodynamical regimes. Thanks to a common netCDF format, this suite is completed with a python library that encompasses all the tools and metrics used to assess the efficiency of the numerical methods. References - Couvelard X., F. Dumas, V. Garnier, A.L. Ponte, C. Talandier, A.M. Treguier (2015). Mixed layer formation and restratification in presence of mesoscale and submesoscale turbulence. Ocean Modelling, Vol 96-2, p 243-253. doi:10.1016/j.ocemod.2015.10.004. - Soufflet Y., P. Marchesiello, F. Lemarié, J. Jouanno, X. Capet, L. Debreu , R. Benshila (2016). On effective resolution in ocean models. Ocean Modelling, in press. doi:10.1016/j.ocemod.2015.12.004

  13. The Influence of Pre-University Students' Mathematics Test Anxiety and Numerical Anxiety on Mathematics Achievement

    ERIC Educational Resources Information Center

    Seng, Ernest Lim Kok

    2015-01-01

    This study examines the relationship between mathematics test anxiety and numerical anxiety on students' mathematics achievement. 140 pre-university students who studied at one of the institutes of higher learning were being investigated. Gender issue pertaining to mathematics anxieties was being addressed besides investigating the magnitude of…

  14. Evaluation of Test Methods for Triaxially Braided Composites using a Meso-Scale Finite Element Model

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zhang, Chao

    The characterization of triaxially braided composite is complicate due to the nonuniformity of deformation within the unit cell as well as the possibility of the freeedge effect related to the large size of the unit cell. Extensive experimental investigation has been conducted to develop more accurate test approaches in characterizing the actual mechanical properties of the material we are studying. In this work, a meso-scale finite element model is utilized to simulate two complex specimens: notched tensile specimen and tube tensile specimen, which are designed to avoid the free-edge effect and free-edge effect induced premature edge damage. The full fieldmore » strain data is predicted numerically and compared with experimental data obtained by Digit Image Correlation. The numerically predicted tensile strength values are compared with experimentally measured results. The discrepancy between numerically predicted and experimentally measured data, the capability of different test approaches are analyzed and discussed. The presented numerical model could serve as assistance to the evaluation of different test methods, and is especially useful in identifying potential local damage events.« less

  15. Spatial and numerical abilities without a complete natural language.

    PubMed

    Hyde, Daniel C; Winkler-Rhoades, Nathan; Lee, Sang-Ah; Izard, Veronique; Shapiro, Kevin A; Spelke, Elizabeth S

    2011-04-01

    We studied the cognitive abilities of a 13-year-old deaf child, deprived of most linguistic input from late infancy, in a battery of tests designed to reveal the nature of numerical and geometrical abilities in the absence of a full linguistic system. Tests revealed widespread proficiency in basic symbolic and non-symbolic numerical computations involving the use of both exact and approximate numbers. Tests of spatial and geometrical abilities revealed an interesting patchwork of age-typical strengths and localized deficits. In particular, the child performed extremely well on navigation tasks involving geometrical or landmark information presented in isolation, but very poorly on otherwise similar tasks that required the combination of the two types of spatial information. Tests of number- and space-specific language revealed proficiency in the use of number words and deficits in the use of spatial terms. This case suggests that a full linguistic system is not necessary to reap the benefits of linguistic vocabulary on basic numerical tasks. Furthermore, it suggests that language plays an important role in the combination of mental representations of space. Copyright © 2010 Elsevier Ltd. All rights reserved.

  16. Application of the inverse analysis for determining the material properties of the woven fabrics for macroscopic approach

    NASA Astrophysics Data System (ADS)

    Oleksik, Mihaela; Oleksik, Valentin

    2013-05-01

    The current paper intends to realise a fast method for determining the material characteristics in the case of composite materials used in the airbags manufacturing. For determining the material data needed for other complex numerical simulations at macroscopic level there was used the inverse analysis method. In fact, there were carried out tensile tests for the composite material extracted along two directions - the direction of the weft and the direction of the warp and afterwards there were realised numerical simulations (using the Ls-Dyna software). A second stage consisted in the numerical simulation through the finite element method and the experimental testing for the Bias test. The material characteristics of the composite fabric material were then obtained by applying a multicriterial analysis using the Ls-Opt software, for which there was imposed a decrease of the mismatch between the force-displacement curves obtained numerically and experimentally, respectively, for both directions (weft and warp) as well as the decrease of the mismatch between the strain - extension curves for two points at the Bias test.

  17. Analysis of Indonesian educational system standard with KSIM cross-impact method

    NASA Astrophysics Data System (ADS)

    Arridjal, F.; Aldila, D.; Bustamam, A.

    2017-07-01

    The Result of The Programme of International Student Assessment (PISA) on 2012 shows that Indonesia is on 64'th position from 65 countries in Mathematics Mean Score. The 2013 Learning Curve Mapping, Indonesia is included in the 10th category of countries with the lowest performance on cognitive skills aspect, i.e. 37'th position from 40 countries. Competency is built by 3 aspects, one of them is cognitive aspect. The low result of mapping on cognitive aspect, describe the low of graduate competences as an output of Indonesia National Education System (INES). INES adopting a concept Eight Educational System Standards (EESS), one of them is graduate competency standard which connected directly with Indonesia's students. This research aims is to model INES by using KSIM cross-impact. Linear regression models of EESS constructed using the accreditation national data of Senior High Schools in Indonesia. The results then interpreted as impact value on the construction of KSIM cross-impact INES. The construction is used to analyze the interaction of EESS and doing numerical simulation for possible public policy in the education sector, i.e. stimulate the growth of education staff standard, content, process and infrastructure. All simulations of public policy has been done with 2 methods i.e with a multiplier impact method and with constant intervention method. From numerical simulation result, it is shown that stimulate the growth standard of content in the construction KSIM cross-impact EESS is the best option for public policy to maximize the growth of graduate competency standard.

  18. Following international trends while subject to past traditions: neuropsychological test use in the Nordic countries.

    PubMed

    Egeland, Jens; Løvstad, Marianne; Norup, Anne; Nybo, Taina; Persson, Bengt A; Rivera, Diego Fernando; Schanke, Anne-Kristine; Sigurdardottir, Solrun; Arango-Lasprilla, Juan Carlos

    2016-01-01

    Historically, the neuropsychological test traditions of the four Nordic countries have spanned from the flexible and qualitative tradition of Luria-Christensen to the quantitative large battery approach of Halstead and Kløve-Matthews. This study reports current test use and discusses whether these traditions still influence attitudes toward test use and choice of tests. The study is based on survey data from 702 Nordic neuropsychologists. The average participant used 9 tests in a standard assessment, and 25 tests overall in their practice. Test use was moderated by nationality, competence level, practice profile, and by attitude toward test selection. Participants who chose their tests flexibly used fewer tests than those adhering to the flexible battery approach, but had fewer tests from which to choose. Testing patients with psychiatric disorders was associated with using more tests. IQ, memory, attention, and executive function were the domains with the largest utilization rate, while tests of motor, visual/spatial, and language were used by few. There is a lack of academic achievement tests. Screening tests played a minor role in specialized assessments, and symptom validity tests were seldom applied on a standard basis. Most tests were of Anglo-American origin. New test methods are implemented rapidly in the Nordic countries, but test selection is also characterized by the dominating position of established and much researched tests. The Halstead-Reitan and Luria traditions are currently weak, but national differences in size of test batteries seem to be influenced by these longstanding traditions.

  19. Development and implementation of a quality assurance program for a hormonal contraceptive implant.

    PubMed

    Owen, Derek H; Jenkins, David; Cancel, Aida; Carter, Eli; Dorflinger, Laneta; Spieler, Jeff; Steiner, Markus J

    2013-04-01

    The importance of the distribution of safe, effective and cost-effective pharmaceutical products in resource-constrained countries is the subject of increasing attention. FHI 360 has developed a program aimed at evaluating the quality of a contraceptive implant manufactured in China, while the product is being registered in an increasing number of countries and distributed by international procurement agencies. The program consists of (1) independent product testing; (2) ongoing evaluation of the manufacturing facility through audits and inspections; and (3) post-marketing surveillance. This article focuses on the laboratory testing of the product. The various test methods were chosen from the following test method compendia, the United States Pharmacopeia (USP), British Pharmacopeia (BP), International Organization for Standardization (ISO), the American Society for Testing and Materials (ASTM), or lot release tests mandated by Chinese regulatory requirements. Each manufactured lot is independently tested prior to its distribution to countries supported by this program. In addition, a more detailed annual testing program includes evaluation of the active ingredient (levonorgestrel), the final product and the packaging material. Over the first 4 years of this 5-year project, all tested lots met the established quality criteria. The quality assurance program developed for this contraceptive implant has helped ensure that a safe product was being introduced into developing country family planning programs. This program provides a template for establishing quality assurance programs for other cost-effective pharmaceutical products that have not yet received stringent regulatory approval and are being distributed in resource-poor settings. Copyright © 2013 Elsevier Inc. All rights reserved.

  20. Income inequality and schizophrenia: increased schizophrenia incidence in countries with high levels of income inequality.

    PubMed

    Burns, Jonathan K; Tomita, Andrew; Kapadia, Amy S

    2014-03-01

    Income inequality is associated with numerous negative health outcomes. There is evidence that ecological-level socio-environmental factors may increase risk for schizophrenia. The aim was to investigate whether measures of income inequality are associated with incidence of schizophrenia at the country level. We conducted a systematic review of incidence rates for schizophrenia, reported between 1975 and 2011. For each country, national measures of income inequality (Gini coefficient) along with covariate risk factors for schizophrenia were obtained. Multi-level mixed-effects Poisson regression was performed to investigate the relationship between Gini coefficients and incidence rates of schizophrenia controlling for covariates. One hundred and seven incidence rates (from 26 countries) were included. Mean incidence of schizophrenia was 18.50 per 100,000 (SD = 11.9; range = 1.7-67). There was a significant positive relationship between incidence rate of schizophrenia and Gini coefficient (β = 1.02; Z = 2.28; p = .02; 95% CI = 1.00, 1.03). Countries characterized by a large rich-poor gap may be at increased risk of schizophrenia. We suggest that income inequality impacts negatively on social cohesion, eroding social capital, and that chronic stress associated with living in highly disparate societies places individuals at risk of schizophrenia.

  1. Handwashing in 51 Countries: Analysis of Proxy Measures of Handwashing Behavior in Multiple Indicator Cluster Surveys and Demographic and Health Surveys, 2010-2013.

    PubMed

    Kumar, Swapna; Loughnan, Libbet; Luyendijk, Rolf; Hernandez, Orlando; Weinger, Merri; Arnold, Fred; Ram, Pavani K

    2017-08-01

    In 2009, a common set of questions addressing handwashing behavior was introduced into nationally representative Demographic and Health Surveys (DHS) and Multiple Indicator Cluster Surveys (MICS), providing large amounts of comparable data from numerous countries worldwide. The objective of this analysis is to describe global handwashing patterns using two proxy indicators for handwashing behavior from 51 DHS and MICS surveys conducted in 2010-2013: availability of soap anywhere in the dwelling and access to a handwashing place with soap and water. Data were also examined across geographic regions, wealth quintiles, and rural versus urban settings. We found large disparities for both indicators across regions, and even among countries within the same World Health Organization region. Within countries, households in lower wealth quintiles and in rural areas were less likely to have soap anywhere in the dwelling and at designated handwashing locations than households in higher wealth quintiles and urban areas. In addition, disparities existed among various geographic regions within countries. This analysis demonstrates the need to promote access to handwashing materials and placement at handwashing locations in the dwelling, particularly in poorer, rural areas where children are more vulnerable to handwashing-preventable syndromes such as pneumonia and diarrhea.

  2. Legal perspectives on cross-border reproductive care.

    PubMed

    Crockin, Susan L

    2011-12-01

    Global cross-border reproductive care (CBRC), and the challenges accompanying it, are here to stay. A recent issue of this journal devoted to CBRC provides an extraordinary array of insights into multiple facets, with a focus on the legal dimensions of practices by restrictive countries such as Turkey and Italy. The articles identify restrictive laws that challenge and create vulnerabilities for both citizens and providers involved in CBRC, and call instead for more modest and nuanced legislation and the closing paper presents a thoughtful and ambitious outline for a future research agenda. This commentary reflects on the implications of these legal dimensions, including their applicability to countries with more permissive CBRC policies, discusses three specific examples of legal concerns that have arisen in the USA and identifies numerous legal issues meriting future study. Together with the nuanced, more modest legislation recommended for restrictive countries, consistent legal and judicial principles for CBRC in permissive countries would respect varying perspectives on family building while attempting to address a central legal concern of CBRC, the protection of families, third-parties and providers. Any future agenda should include research and recommendations on the legal dimensions of CBRC in both restrictive and permissive countries. Copyright © 2011 Reproductive Healthcare Ltd. Published by Elsevier Ltd. All rights reserved.

  3. Comparing antibiotic consumption between two European countries: are packages an adequate surrogate for prescriptions?

    PubMed

    Watier, Laurence; Cavalié, Philippe; Coignard, Bruno; Brun-Buisson, Christian

    2017-11-01

    Defined daily doses (DDD) are the gold standard indicator for quantifying prescriptions. Since 2014, the European Centre for Disease Prevention and Control (ECDC) has also been using the number of packages per 1,000 inhabitants per day (ipd), as a surrogate for prescriptions, to report antibiotic consumption in the community and to perform comparisons between European Union (EU) countries participating in the European Surveillance of Antimicrobial Consumption Network (ESAC-Net). In 2015, consumption was reported to range across Europe from 1.0 to 4.7 packages per 1,000 ipd. Our analysis showed that consumption of antibiotics for systemic use per 1,000 ipd was on average 1.3 times greater in France than in Belgium when considering prescriptions in the numerator, 2.5 times greater when considering packages and 1.2 times greater when considering DDD. As long as the same metrics are used over time, antibiotic consumption data aggregated and disseminated by ECDC are useful for assessing temporal trends at the European level and within individual countries; these data may also be used for benchmarking across EU countries. While DDD - although imperfect - are the most widely accepted metric for this purpose, antibiotic packages do not appear suitable for comparisons between countries and may be misleading.

  4. Comparing antibiotic consumption between two European countries: are packages an adequate surrogate for prescriptions?

    PubMed Central

    Watier, Laurence; Cavalié, Philippe; Coignard, Bruno; Brun-Buisson, Christian

    2017-01-01

    Defined daily doses (DDD) are the gold standard indicator for quantifying prescriptions. Since 2014, the European Centre for Disease Prevention and Control (ECDC) has also been using the number of packages per 1,000 inhabitants per day (ipd), as a surrogate for prescriptions, to report antibiotic consumption in the community and to perform comparisons between European Union (EU) countries participating in the European Surveillance of Antimicrobial Consumption Network (ESAC-Net). In 2015, consumption was reported to range across Europe from 1.0 to 4.7 packages per 1,000 ipd. Our analysis showed that consumption of antibiotics for systemic use per 1,000 ipd was on average 1.3 times greater in France than in Belgium when considering prescriptions in the numerator, 2.5 times greater when considering packages and 1.2 times greater when considering DDD. As long as the same metrics are used over time, antibiotic consumption data aggregated and disseminated by ECDC are useful for assessing temporal trends at the European level and within individual countries; these data may also be used for benchmarking across EU countries. While DDD - although imperfect - are the most widely accepted metric for this purpose, antibiotic packages do not appear suitable for comparisons between countries and may be misleading. PMID:29162212

  5. Handwashing in 51 Countries: Analysis of Proxy Measures of Handwashing Behavior in Multiple Indicator Cluster Surveys and Demographic and Health Surveys, 2010–2013

    PubMed Central

    Kumar, Swapna; Loughnan, Libbet; Luyendijk, Rolf; Hernandez, Orlando; Weinger, Merri; Arnold, Fred; Ram, Pavani K.

    2017-01-01

    Abstract. In 2009, a common set of questions addressing handwashing behavior was introduced into nationally representative Demographic and Health Surveys (DHS) and Multiple Indicator Cluster Surveys (MICS), providing large amounts of comparable data from numerous countries worldwide. The objective of this analysis is to describe global handwashing patterns using two proxy indicators for handwashing behavior from 51 DHS and MICS surveys conducted in 2010–2013: availability of soap anywhere in the dwelling and access to a handwashing place with soap and water. Data were also examined across geographic regions, wealth quintiles, and rural versus urban settings. We found large disparities for both indicators across regions, and even among countries within the same World Health Organization region. Within countries, households in lower wealth quintiles and in rural areas were less likely to have soap anywhere in the dwelling and at designated handwashing locations than households in higher wealth quintiles and urban areas. In addition, disparities existed among various geographic regions within countries. This analysis demonstrates the need to promote access to handwashing materials and placement at handwashing locations in the dwelling, particularly in poorer, rural areas where children are more vulnerable to handwashing-preventable syndromes such as pneumonia and diarrhea. PMID:28722572

  6. Potential Production of Sterigmatocystin on Country-Cured Ham

    PubMed Central

    Halls, N. A.; Ayres, J. C.

    1973-01-01

    In laboratory media, 10 of 16 isolates of Aspergillus versicolor from country-cured ham were capable of producing sterigmatocystin. Three of these isolates were tested and found to produce sterigmatocystin on country-cured ham after 14 days of incubation at 20 or 28 C. PMID:4751808

  7. Current and future use of point-of-care tests in primary care: an international survey in Australia, Belgium, The Netherlands, the UK and the USA

    PubMed Central

    Howick, Jeremy; Cals, Jochen W L; Jones, Caroline; Price, Christopher P; Plüddemann, Annette; Heneghan, Carl; Berger, Marjolein Y; Buntinx, Frank; Hickner, John; Pace, Wilson; Badrick, Tony; Van den Bruel, Ann; Laurence, Caroline; van Weert, Henk C; van Severen, Evie; Parrella, Adriana; Thompson, Matthew

    2014-01-01

    Objective Despite the growing number of point-of-care (POC) tests available, little research has assessed primary care clinician need for such tests. We therefore aimed to determine which POC tests they actually use or would like to use (if not currently available in their practice). Design Cross-sectional survey. Setting Primary care in Australia, Belgium (Flanders region only), the Netherlands, the UK and the USA. Participants Primary care doctors (general practitioners, family physicians). Main measures We asked respondents to (1) identify conditions for which a POC test could help inform diagnosis, (2) from a list of tests provided: evaluate which POC tests they currently use (and how frequently) and (3) determine which tests (from that same list) they would like to use in the future (and how frequently). Results 2770 primary care clinicians across five countries responded. Respondents in all countries wanted POC tests to help them diagnose acute conditions (infections, acute cardiac disease, pulmonary embolism/deep vein thrombosis), and some chronic conditions (diabetes, anaemia). Based on the list of POC tests provided, the most common tests currently used were: urine pregnancy, urine leucocytes or nitrite and blood glucose. The most commonly reported tests respondents expressed a wish to use in the future were: D-dimer, troponin and chlamydia. The UK and the USA reported a higher actual and desired use for POC tests than Australia, Belgium and the Netherlands. Our limited data suggest (but do not confirm) representativeness. Conclusions Primary care clinicians in all five countries expressed a desire for POC tests to help them diagnose a range of acute and chronic conditions. Rates of current reported use and desired future use were generally high for a small selection of POC tests, but varied across countries. Future research is warranted to explore how specific POC tests might improve primary care. PMID:25107438

  8. Dominance and leadership in research activities: Collaboration between countries of differing human development is reflected through authorship order and designation as corresponding authors in scientific publications

    PubMed Central

    Park, Jinseo; Huamaní, Charles; Ramos, José M.

    2017-01-01

    Introduction Scientific collaboration is an important mechanism that enables the integration of the least developed countries into research activities. In the present study, we use the order of author signatures and addresses for correspondence in scientific publications as variables to analyze the interactions between countries of very high (VHHD), high (HHD), medium (MHD), and low human development (LHD). Methodology We identified all documents published between 2011 and 2015 in journals included in the Science Citation Index-Expanded categories’ of Tropical Medicine, Infectious Diseases, Parasitology, and Pediatrics. We then classified the countries participating in the publications according to their Human Development Index (HDI), analyzing the international collaboration; positioning and influence of some countries over others in cooperative networks; their leadership; and the impact of the work based on the HDI and the type of collaboration. Results We observed a high degree of international collaboration in all the areas analyzed, in the case of both LHD and MHD countries. We identified numerous cooperative links between VHHD countries and MHD/LHD countries, reflecting the fact that cooperative links are an important mechanism for integrating research activities into the latter. The countries with large emerging economies, such as Brazil and China stand out due to the dominance they exert in the collaborations established with the United States, the UK, and other European countries. The analysis of the leadership role of the countries, measured by the frequency of lead authorships, shows limited participation by MHD/LHD countries. This reduced participation among less developed countries is further accentuated by their limited presence in the addresses for correspondence. We observed significant statistical differences in the degree of citation according to the HDI of the participating countries. Conclusions The order of signatures and the address for correspondence in scientific publications are bibliographic characteristics that facilitate a precise, in-depth analysis of cooperative practices and their associations with concepts like dominance or leadership. This is useful to monitor the existing balance in research participation in health research publications. PMID:28792519

  9. Interdependent networks - Topological percolation research and application in finance

    NASA Astrophysics Data System (ADS)

    Zhou, Di

    This dissertation covers the two major parts of my Ph.D. research: i) developing a theoretical framework of complex networks and applying simulation and numerical methods to study the robustness of the network system, and ii) applying statistical physics concepts and methods to quantitatively analyze complex systems and applying the theoretical framework to study real-world systems. In part I, we focus on developing theories of interdependent networks as well as building computer simulation models, which includes three parts: 1) We report on the effects of topology on failure propagation for a model system consisting of two interdependent networks. We find that the internal node correlations in each of the networks significantly changes the critical density of failures, which can trigger the total disruption of the two-network system. Specifically, we find that the assortativity within a single network decreases the robustness of the entire system. 2) We study the percolation behavior of two interdependent scale-free (SF) networks under random failure of 1-p fraction of nodes. We find that as the coupling strength q between the two networks reduces from 1 (fully coupled) to 0 (no coupling), there exist two critical coupling strengths q1 and q2 , which separate the behaviors of the giant component as a function of p into three different regions, and for q2 < q < q 1 , we observe a hybrid order phase transition phenomenon. 3) We study the robustness of n interdependent networks with partially support-dependent relationship both analytically and numerically. We study a starlike network of n Erdos-Renyi (ER), SF networks and a looplike network of n ER networks, and we find for starlike networks, their phase transition regions change with n, but for looplike networks the phase regions change with average degree k . In part II, we apply concepts and methods developed in statistical physics to study economic systems. We analyze stock market indices and foreign exchange daily returns for 60 countries over the period of 1999-2012. We build a multi-layer network model based on different correlation measures, and introduce a dynamic network model to simulate and analyze the initializing and spreading of financial crisis. Using different computational approaches and econometric tests, we find atypical behavior of the cross correlations and community formations in the financial networks that we study during the financial crisis of 2008. For example, the overall correlation of stock market increases during crisis while the correlation between stock market and foreign exchange market decreases. The dramatic increase in correlations between a specific nation and other nations may indicate that this nation could trigger a global financial crisis. Specifically, core countries that have higher correlations with other countries and larger Gross Domestic Product (GDP) values spread financial crisis quite effectively, yet some countries with small GDPs like Greece and Cyprus are also effective in propagating systemic risk and spreading global financial crisis.

  10. Numerical Study of Magnetic Damping During Unidirectional Solidification

    NASA Technical Reports Server (NTRS)

    Li, Ben Q.

    1997-01-01

    A fully 3-D numerical model is developed to represent magnetic damping of complex fluid flow, heat transfer and electromagnetic field distributions in a melt cavity. The model is developed based on our in-house finite element code for the fluid flow, heat transfer and electromagnetic field calculations. The computer code has been tested against benchmark test problems that are solved by other commercial codes as well as analytical solutions whenever available. The numerical model is tested against numerical and experimental results for water reported in literature. With the model so tested, various numerical simulations are carried out for the Sn-35.5% Pb melt convection and temperature distribution in a cylindrical cavity with and without the presence of a transverse magnetic field. Numerical results show that magnetic damping can be effectively applied to reduce turbulence and flow levels in the melt undergoing solidification and over a certain threshold value a higher magnetic field resulted in a higher velocity reduction. It is found also that for a fully 3-D representation of the magnetic damping effects, the electric field induced in the melt by the applied DC magnetic field does not vanish, as some researchers suggested, and must be included even for molten metal and semiconductors. Also, for the study of the melt flow instability, a long enough time has to be applied to ensure the final fluid flow recirculation pattern. Moreover, our numerical results suggested that there seems to exist a threshold value of applied magnetic field, above which magnetic damping becomes possible and below which the convection in the melt is actually enhanced. Because of the limited financial resource allocated for the project, we are unable to carry out extensive study on this effect, which should warrant further theoretical and experimental study. In that endeavor, the developed numerical model should be very useful; and the model should serve as a useful tool for exploring necessary design parameters for planning magnetic damping experiments and interpreting the experimental results.

  11. WEC-SIM Phase 1 Validation Testing -- Numerical Modeling of Experiments: Preprint

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ruehl, Kelley; Michelen, Carlos; Bosma, Bret

    2016-08-01

    The Wave Energy Converter Simulator (WEC-Sim) is an open-source code jointly developed by Sandia National Laboratories and the National Renewable Energy Laboratory. It is used to model wave energy converters subjected to operational and extreme waves. In order for the WEC-Sim code to be beneficial to the wave energy community, code verification and physical model validation is necessary. This paper describes numerical modeling of the wave tank testing for the 1:33-scale experimental testing of the floating oscillating surge wave energy converter. The comparison between WEC-Sim and the Phase 1 experimental data set serves as code validation. This paper is amore » follow-up to the WEC-Sim paper on experimental testing, and describes the WEC-Sim numerical simulations for the floating oscillating surge wave energy converter.« less

  12. Diffusion of counterfeit drugs in developing countries and stability of galenics stored for months under different conditions of temperature and relative humidity.

    PubMed

    Baratta, Francesca; Germano, Antonio; Brusa, Paola

    2012-04-01

    To investigate the diffusion of counterfeit medicines in developing countries and to verify the stability of galenic dosage forms to determine the stability of galenics prepared and stored in developing countries. We purchased 221 pharmaceutical samples belonging to different therapeutic classes both in authorized and illegal pharmacies and subjected them to European Pharmacopoeia, 7th ed. quality tests. An UV-visible spectrophotometric assay was used to determine the galenics stability under different conditions of temperature (T) and relative humidity (RH). A substantial percentage of samples was substandard (52%) and thus had to be considered as counterfeit. Stability tests for galenics showed that the tested dosage forms were stable for 24 months under "standard" (t=25±2°C, RH=50±5%) conditions. Under "accelerated" (t=40±2°C, RH=50±5%) conditions, samples were stable for 3 months provided that they were stored in glass containers. Stability results of samples stored in "accelerated" conditions were similar to those obtained by on site in tropical countries and could so supply precious information on the expected stability of galenics in tropical countries. This study gives useful information about the presence of counterfeit medicinal products in the pharmacies of many developing countries. This should serve as an alarm bell and an input for the production of galenics. We recommend setting up of galenic laboratories in developing countries around the globe.

  13. Preconception health assessment in China, Lebanon and the Philippines: applicability to other countries.

    PubMed

    Reeve, Mary-Elizabeth; Charafeddine, Lama; Zhong, Nanbert; Padilla, Carmencita D; Yunis, Khalid; El Rafei, Reem; Alamiddine, Kawthar; Zhao, Xinliang; Jiang, Xiaoqing; Howson, Christopher P

    2014-07-01

    To test the utility of a preconception checklist tool in identifying preconception health needs of women in three countries; China, Lebanon and the Philippines. An academic medical center within each country participated in the development and testing of a preconception checklist tool, which was administered over a 6 month period to selected target groups in each country. The checklist provided valuable data on the preconception health of 6,530 women. Aggregated data identified common preconception health needs across all countries, including provision of modern contraceptives and adequate immunization coverage; HIV and STI screening; treatment for anemia; and counseling for maintenance of a healthy weight. A preconception checklist tool was found to be useful in distinct cultural settings. The study was a pilot. Future steps include validation and standardization of the checklist, data from which could be used to help shape preconception care policies and implementation strategies.

  14. A simple landslide susceptibility analysis for hazard and risk assessment in developing countries

    NASA Astrophysics Data System (ADS)

    Guinau, M.; Vilaplana, J. M.

    2003-04-01

    In recent years, a number of techniques and methodologies have been developed for mitigating natural disasters. The complexity of these methodologies and the scarcity of material and data series justify the need for simple methodologies to obtain the necessary information for minimising the effects of catastrophic natural phenomena. The work with polygonal maps using a GIS allowed us to develop a simple methodology, which was developed in an area of 473 Km2 in the Departamento de Chinandega (NW Nicaragua). This area was severely affected by a large number of landslides (mainly debris flows), triggered by the Hurricane Mitch rainfalls in October 1998. With the aid of aerial photography interpretation at 1:40.000 scale, amplified to 1:20.000, and detailed field work, a landslide map at 1:10.000 scale was constructed. The failure zones of landslides were digitized in order to obtain a failure zone digital map. A terrain unit digital map, in which a series of physical-environmental terrain factors are represented, was also used. Dividing the studied area into two zones (A and B) with homogeneous physical and environmental characteristics, allows us to develop the proposed methodology and to validate it. In zone A, the failure zone digital map is superimposed onto the terrain unit digital map to establish the relationship between the different terrain factors and the failure zones. The numerical expression of this relationship enables us to classify the terrain by its landslide susceptibility. In zone B, this numerical relationship was employed to obtain a landslide susceptibility map, obviating the need for a failure zone map. The validity of the methodology can be tested in this area by using the degree of superposition of the susceptibility map and the failure zone map. The implementation of the methodology in tropical countries with physical and environmental characteristics similar to those of the study area allows us to carry out a landslide susceptibility analysis in areas where landslide records do not exist. This analysis is essential to landslide hazard and risk assessment, which is necessary to determine the actions for mitigating landslide effects, e.g. land planning, emergency aid actions, etc.

  15. 22 CFR 96.49 - Provision of medical and social information in incoming cases.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... on the known health risks in the specific region or country where the child resides. (e) If the...) Information about the full range of any tests performed on the child, including tests addressing known risk factors in the child's country of origin; and (6) Current health information. (f) The agency or person...

  16. Priming International Affairs: How the Media Influence Attitudes toward Foreign Countries.

    ERIC Educational Resources Information Center

    Willnat, Lars; Graf, Joseph; Brewer, Paul R.

    This study broadens the scope of priming research by testing whether media coverage of international affairs shapes the criteria which people use to judge foreign countries. In contrast to previous priming experiments that focused on the effects of television news stories, this study experimentally tests the power of print media to produce priming…

  17. PISA 2012: How Do Results for the Paper and Computer Tests Compare?

    ERIC Educational Resources Information Center

    Jerrim, John

    2016-01-01

    The Programme for International Assessment (PISA) is an important cross-national study of 15-year olds academic achievement. Although it has traditionally been conducted using paper-and-pencil tests, the vast majority of countries will use computer-based assessment from 2015. In this paper, we consider how cross-country comparisons of children's…

  18. Trends of improved water and sanitation coverage around the globe between 1990 and 2010: inequality among countries and performance of official development assistance

    PubMed Central

    Cha, Seungman; Mankadi, Paul Mansiangi; Elhag, Mousab Siddig; Lee, Yongjoo; Jin, Yan

    2017-01-01

    ABSTRACT Background: As the Millennium Development Goals ended, and were replaced by the Sustainable Development Goals, efforts have been made to evaluate the achievements and performance of official development assistance (ODA) in the health sector. In this study, we explore trends in the expansion of water and sanitation coverage in developing countries and the performance of ODA. Design: We explored inequality across developing countries by income level, and investigated how ODA for water and sanitation was committed by country, region, and income level. Changes in inequality were tested via slope changes by investigating the interaction of year and income level with a likelihood ratio test. A random effects model was applied according to the results of the Hausman test. Results: The slope of the linear trend between economic level and sanitation coverage has declined over time. However, a random effects model suggested that the change in slope across years was not significant (e.g. for the slope change between 2000 and 2010: likelihood ratio χ2 = 2.49, probability > χ2 = 0.1146). A similar pro-rich pattern across developing countries and a non-significant change in the slope associated with different economic levels were demonstrated for water coverage. Our analysis shows that the inequality of water and sanitation coverage among countries across the world has not been addressed effectively during the past decade. Our findings demonstrate that the countries with the least coverage persistently received far less ODA per capita than did countries with much more extensive water and sanitation coverage, suggesting that ODA for water and sanitation is poorly targeted. Conclusion: The most deprived countries should receive more attention for water and sanitation improvements from the world health community. A strong political commitment to ODA targeting the countries with the least coverage is needed at the global level. PMID:28604256

  19. Improving global estimates of syphilis in pregnancy by diagnostic test type: A systematic review and meta-analysis.

    PubMed

    Ham, D Cal; Lin, Carol; Newman, Lori; Wijesooriya, N Saman; Kamb, Mary

    2015-06-01

    "Probable active syphilis," is defined as seroreactivity in both non-treponemal and treponemal tests. A correction factor of 65%, namely the proportion of pregnant women reactive in one syphilis test type that were likely reactive in the second, was applied to reported syphilis seropositivity data reported to WHO for global estimates of syphilis during pregnancy. To identify more accurate correction factors based on test type reported. Medline search using: "Syphilis [Mesh] and Pregnancy [Mesh]," "Syphilis [Mesh] and Prenatal Diagnosis [Mesh]," and "Syphilis [Mesh] and Antenatal [Keyword]. Eligible studies must have reported results for pregnant or puerperal women for both non-treponemal and treponemal serology. We manually calculated the crude percent estimates of subjects with both reactive treponemal and reactive non-treponemal tests among subjects with reactive treponemal and among subjects with reactive non-treponemal tests. We summarized the percent estimates using random effects models. Countries reporting both reactive non-treponemal and reactive treponemal testing required no correction factor. Countries reporting non-treponemal testing or treponemal testing alone required a correction factor of 52.2% and 53.6%, respectively. Countries not reporting test type required a correction factor of 68.6%. Future estimates should adjust reported maternal syphilis seropositivity by test type to ensure accuracy. Published by Elsevier Ireland Ltd.

  20. Perinatal Exposure of Mice to the Pesticide DDT Impairs Energy Expenditure and Metabolism in Adult Female Offspring

    PubMed Central

    La Merrill, Michele; Karey, Emma; Moshier, Erin; Lindtner, Claudia; La Frano, Michael R.; Newman, John W.; Buettner, Christoph

    2014-01-01

    Dichlorodiphenyltrichloroethane (DDT) has been used extensively to control malaria, typhus, body lice and bubonic plague worldwide, until countries began restricting its use in the 1970s. Its use in malaria control continues in some countries according to recommendation by the World Health Organization. Individuals exposed to elevated levels of DDT and its metabolite dichlorodiphenyldichloroethylene (DDE) have an increased prevalence of diabetes and insulin resistance. Here we hypothesize that perinatal exposure to DDT disrupts metabolic programming leading to impaired metabolism in adult offspring. To test this, we administered DDT to C57BL/6J mice from gestational day 11.5 to postnatal day 5 and studied their metabolic phenotype at several ages up to nine months. Perinatal DDT exposure reduced core body temperature, impaired cold tolerance, decreased energy expenditure, and produced a transient early-life increase in body fat in female offspring. When challenged with a high fat diet for 12 weeks in adulthood, female offspring perinatally exposed to DDT developed glucose intolerance, hyperinsulinemia, dyslipidemia, and altered bile acid metabolism. Perinatal DDT exposure combined with high fat feeding in adulthood further impaired thermogenesis as evidenced by reductions in core temperature and in the expression of numerous RNA that promote thermogenesis and substrate utilization in the brown adipose tissue of adult female mice. These observations suggest that perinatal DDT exposure impairs thermogenesis and the metabolism of carbohydrates and lipids which may increase susceptibility to the metabolic syndrome in adult female offspring. PMID:25076055

  1. The contributions of numerical acuity and non-numerical stimulus features to the development of the number sense and symbolic math achievement.

    PubMed

    Starr, Ariel; DeWind, Nicholas K; Brannon, Elizabeth M

    2017-11-01

    Numerical acuity, frequently measured by a Weber fraction derived from nonsymbolic numerical comparison judgments, has been shown to be predictive of mathematical ability. However, recent findings suggest that stimulus controls in these tasks are often insufficiently implemented, and the proposal has been made that alternative visual features or inhibitory control capacities may actually explain this relation. Here, we use a novel mathematical algorithm to parse the relative influence of numerosity from other visual features in nonsymbolic numerical discrimination and to examine the strength of the relations between each of these variables, including inhibitory control, and mathematical ability. We examined these questions developmentally by testing 4-year-old children, 6-year-old children, and adults with a nonsymbolic numerical comparison task, a symbolic math assessment, and a test of inhibitory control. We found that the influence of non-numerical features decreased significantly over development but that numerosity was a primary determinate of decision making at all ages. In addition, numerical acuity was a stronger predictor of math achievement than either non-numerical bias or inhibitory control in children. These results suggest that the ability to selectively attend to number contributes to the maturation of the number sense and that numerical acuity, independent of inhibitory control, contributes to math achievement in early childhood. Copyright © 2017 Elsevier B.V. All rights reserved.

  2. A Measurement Invariance Analysis of the General Self-Efficacy Scale on Two Different Cultures

    ERIC Educational Resources Information Center

    Teo, Timothy; Kam, Chester

    2014-01-01

    The 10-item General Self-Efficacy Scale (GSES) was developed to assess an individual's beliefs to cope with a variety of situations in life. Despite the GSES being used in numerous research from researchers in different countries and presented in different languages, little is known about the use of its validity in an Asian culture. The aim of the…

  3. Coordination and Data Management of the International Arctic Buoy Programme (IABP)

    DTIC Science & Technology

    2002-09-30

    for forcing, validation and assimilation into numerical climate models , and for forecasting weather and ice conditions. TRANSITIONS Using IABP ...Coordination and Data Management of the International Arctic Buoy Programme ( IABP ) Ignatius G. Rigor 1013 NE 40th Street Polar Science Center...analyzed geophysical fields. APPROACH The IABP is a collaboration between 25 different institutions from 8 different countries, which work together

  4. The Design and Development of a Web-Based E-Learning Platform for the Understanding and Acquisition of Various Entrepreneurial Skills in SMEs and Industry

    ERIC Educational Resources Information Center

    Ogunleye, Ayodele; Owolabi, Tunde; Adeyemo, Sunday

    2013-01-01

    In recent times, the role of entrepreneurs has been recognized to be of great significance in accelerating the pace of growth of economic development of any country. Internet-enabled technologies have also challenged existing business models in numerous market sectors and offered innovation opportunities to a variety of stakeholders--not least…

  5. Microelectronics: The Nature of Work, Skills and Training. An Analysis of Case Studies from Developed and Developing Countries. Training Discussion Paper No. 51.

    ERIC Educational Resources Information Center

    Acero, Liliana

    Microelectronic technologies have had an impact on the nature of work in industry for both white-collar and blue-collar workers. Evidence from sector- and enterprise-level studies shows changes in skills and job content for blue-collar workers involved with numerically controlled machine tools, robots, and other microelectronics applications.…

  6. Telemicrobiology for Mission Support in the Field of Infectious Diseases

    DTIC Science & Technology

    2010-04-01

    bacterial meningitis so that important additional verification was lacking. Microscopic diagnoses in the expert laboratory also rarely yield a...With bacterial infections, depending on the country of deployment, also unusual resistance behavior of the pathogens will occur because numerous...missions of the US Forces in the recent years, well-documented with respect to epidemiology , the weekly incidence of infectious diseases was always

  7. [Contribution of the US Army Nurse Corps to the First World War].

    PubMed

    Vane, Elizabeth A P; Marble, Sanders

    2014-06-01

    A number of American nurses, on an individual basis, gave their assistance to European countries as soon as war was declared, in 1914. In 1917, when the United States entered the war, nurses from the American army arrived on the European continent before the troops. They made a major contribution to the conflict, as testified by the numerous medals they were awarded.

  8. The Short-Run Effects of the Croatian War on Education, Employment, and Earnings

    ERIC Educational Resources Information Center

    Kecmanovic, Milica

    2013-01-01

    The recent war in Croatia (1991-1995) has had numerous adverse affects on the country and the economy as a whole. This article investigates the effect that the war had on the educational, employment, and earnings trajectories of the 1971 birth cohort of men. This birth cohort was very likely to be drafted into the armed forces. Using data from the…

  9. Making the Most of the American Recovery and Reinvestment Act of 2009: A Guide for Full-Service School Leaders and Community Partners

    ERIC Educational Resources Information Center

    Gaughen, Katherine; Stewart, Nichole H.; LaVallee, Robert; Zvara, Alexandra

    2009-01-01

    To address the economic crisis facing the country, the President signed the American Recovery and Reinvestment Act (ARRA) into law on February 17, 2009. The ARRA offers numerous opportunities for full-service school leaders and may provide the necessary funding to prevent significant decreases in operating budgets. One of the largest investments…

  10. Risk of Autism Associated with General Anesthesia during Cesarean Delivery: A Population-Based Birth-Cohort Analysis

    ERIC Educational Resources Information Center

    Chien, Li-Nien; Lin, Hsiu-Chen; Shao, Yu-Hsuan Joni; Chiou, Shu-Ti; Chiou, Hung-Yi

    2015-01-01

    The rates of Cesarean delivery (C-section) have risen to >30 % in numerous countries. Increased risk of autism has been shown in neonates delivered by C-section. This study examined the incidence of autism in neonates delivered vaginally, by C-section with regional anesthesia (RA), and by C-section with general anesthesia (GA) to evaluate the…

  11. Scandiatransplant: organ transplantation in the Nordic countries 1996.

    PubMed

    Madsen, M; Asmundsson, P; Brekke, I B; Höckerstedt, K; Kirkegaard, P; Persson, N H; Tufveson, G

    1997-11-01

    The Nordic collaboration in organ transplantation was initiated nearly 30 years ago in the frame of Scandiatransplant. With a recent formalization of its structure, Scandiatransplant has become a modern organ exchange organization. The increasing activities of Scandiatransplant clearly reflect the continuously growing need for a close and firm Nordic collaboration in the transplantation field, for the benefit of the numerous patients waiting for an organ transplant.

  12. AIDS-related discrimination in Asia.

    PubMed

    Paxton, S; Gonzales, G; Uppakaew, K; Abraham, K K; Okta, S; Green, C; Nair, K S; Merati, T Parwati; Thephthien, B; Marin, M; Quesada, A

    2005-05-01

    The Asia Pacific Network of People Living with HIV/AIDS (APN+) conducted the first regional documentation of AIDS-related discrimination in Asia. This project was an action-based, peer-implemented study that aimed to develop an understanding of the nature, pattern and extent of AIDS-related discrimination in several Asian countries. Trained HIV-positive people interviewed 764 positive people in four countries (India 302; Indonesia 42; Thailand 338; the Philippines 82) using a structured questionnaire. Findings indicate that the major area of discrimination in each country is within the health sector, where over half of those surveyed experienced some form of discrimination. In all countries, the majority of people did not receive pre-test counselling before being tested for HIV. People who reported coerced testing were significantly more likely than other respondents to face subsequent AIDS-related discrimination. A considerable number of respondents were refused treatment after being diagnosed with HIV and many experienced delayed provision of treatment or health services. Breaches of confidentiality by health workers were common. Within the family and the community, women were significantly more likely to experience discrimination than men, including ridicule and harassment, physical assault and being forced to change their place of residence because of their HIV status. These findings have serious implications, particularly in light of the increasing trend in many countries to test all pregnant women in order to prevent transmission of HIV to their unborn children.

  13. Entrepreneurial Intentions in Developing and Developed Countries

    ERIC Educational Resources Information Center

    Iakovleva, Tatiana; Kolvereid, Lars; Stephan, Ute

    2011-01-01

    Purpose: This study proposes to use the Theory of Planned Behaviour to predict entrepreneurial intentions among students in five developing and nine developed countries. The purpose is to investigate whether entrepreneurial intention and its antecedents differ between developing and developed countries, and to test the theory in the two groups of…

  14. 7 CFR 3300.58 - General.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... States or in test facilities located in, and approved by, a foreign country which is a Contracting Party... may receive a U.S. ATP certiticate in exchange for the Foreign-ATP certificate issued by the country... and approved by a foreign country which is a Contracting Party. (f) In accordance with ATP, Annex 1...

  15. 7 CFR 3300.58 - General.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... States or in test facilities located in, and approved by, a foreign country which is a Contracting Party... may receive a U.S. ATP certiticate in exchange for the Foreign-ATP certificate issued by the country... and approved by a foreign country which is a Contracting Party. (f) In accordance with ATP, Annex 1...

  16. Methodology for the development of normative data for Spanish-speaking pediatric populations.

    PubMed

    Rivera, D; Arango-Lasprilla, J C

    2017-01-01

    To describe the methodology utilized to calculate reliability and the generation of norms for 10 neuropsychological tests for children in Spanish-speaking countries. The study sample consisted of over 4,373 healthy children from nine countries in Latin America (Chile, Cuba, Ecuador, Guatemala, Honduras, Mexico, Paraguay, Peru, and Puerto Rico) and Spain. Inclusion criteria for all countries were to have between 6 to 17 years of age, an Intelligence Quotient of≥80 on the Test of Non-Verbal Intelligence (TONI-2), and score of <19 on the Children's Depression Inventory. Participants completed 10 neuropsychological tests. Reliability and norms were calculated for all tests. Test-retest analysis showed excellent or good- reliability on all tests (r's>0.55; p's<0.001) except M-WCST perseverative errors whose coefficient magnitude was fair. All scores were normed using multiple linear regressions and standard deviations of residual values. Age, age2, sex, and mean level of parental education (MLPE) were included as predictors in the models by country. The non-significant variables (p > 0.05) were removed and the analysis were run again. This is the largest Spanish-speaking children and adolescents normative study in the world. For the generation of normative data, the method based on linear regression models and the standard deviation of residual values was used. This method allows determination of the specific variables that predict test scores, helps identify and control for collinearity of predictive variables, and generates continuous and more reliable norms than those of traditional methods.

  17. THE EMERGENCE OF NUMERICAL AIR QUALITY FORECASTING MODELS AND THEIR APPLICATION

    EPA Science Inventory

    In recent years the U.S. and other nations have begun programs for short-term local through regional air quality forecasting based upon numerical three-dimensional air quality grid models. These numerical air quality forecast (NAQF) models and systems have been developed and test...

  18. THE EMERGENCE OF NUMERICAL AIR QUALITY FORCASTING MODELS AND THEIR APPLICATIONS

    EPA Science Inventory

    In recent years the U.S. and other nations have begun programs for short-term local through regional air quality forecasting based upon numerical three-dimensional air quality grid models. These numerical air quality forecast (NAQF) models and systems have been developed and test...

  19. Hotspots within the Transboundary Selenga River Basin

    NASA Astrophysics Data System (ADS)

    Kasimov, Nikolay; Lychagin, Mikhail; Chalov, Sergey

    2013-04-01

    Gathering the efficient information on water pollution of transboundary river systems remains the crucial task in international water management, environmental pollution control and prevention health problems. Countries, located in the low parts of the river basins, depend on the water strategy and water use in the adjacent countries, located upstream. Surface water pollution is considered to be the most serious problem, facing the above-mentioned countries. Large efforts in terms of field measurement campaigns and (numerical) transport modeling are then typically needed for relevant pollution prediction and prevention. Russian rivers take inflow from 8 neighboring countries. Among them there are 2 developing economies - People Republic of China and Mongolia, which are located in water-scarce areas and thus solve their water-related problems through the consumption of international water. Negative change of water runoff and water quality in the foreign part of transboundary river is appeared inside Russian territory with more or less delay. The transboundary river system of Selenga is particularly challenging, being the biggest tributary of Lake Baikal which is the largest freshwater reservoir in the world. Selenga River contributes about 50 % of the total inflow into Baikal. It originates in the mountainous part of Mongolia and then drains into Russia. There are numerous industries and agricultural activities within the Selenga drainage basin that affect the water quality of the river system. Absence of the single monitoring system and predictive tools for pollutants transport in river system requires large efforts in understanding sources of water pollution and implemented data on the relevant numerical systems for the pollution prediction and prevention. Special investigations in the Selenga river basin (Mongolia and Russia) were done to assess hot spots and understand state-of-the art in sediment load, water chemistry and hydrobiology of transboundary systems. Hot spot assessment included 100 gauge stations in the river basin with discharge measurement by ADCP, turbidity (T) and suspended sediment concentration (SSC), bed load by bed load traps, composition of salt, biochemical oxidation, nitrogen and phosphorous content in water, pH, redox and conductivity values, and also content of heavy metals in water, suspended matter and sediments. The study revealed rather high levels of dissolved Fe, Al, Mn, Zn, Cu, and Mo in the Selenga River water which often are higher than MPC for water fishery. Most contrast distribution is characteristic for W and Mo, which is caused by mineral deposits in the Selenga basin. The most severe pollution of aquatic systems in the basin caused by mining activities is characteristic for a small river Modonkul, which flows into Dzhida River (left tributary of Selenga).

  20. An Experimental and Numerical Comparison of the Rupture Locations of an Abdominal Aortic Aneurysm

    PubMed Central

    Doyle, Barry J.; Corbett, Timothy J.; Callanan, Anthony; Walsh, Michael T.; Vorp, David A.; McGloughlin, Timothy M.

    2009-01-01

    Purpose: To identify the rupture locations of idealized physical models of abdominal aortic aneurysm (AAA) using an in-vitro setup and to compare the findings to those predicted numerically. Methods: Five idealized AAAs were manufactured using Sylgard 184 silicone rubber, which had been mechanically characterized from tensile tests, tear tests, and finite element analysis. The models were then inflated to the point of rupture and recorded using a high-speed camera. Numerical modeling attempted to confirm these rupture locations. Regional variations in wall thickness of the silicone models was also quantified and applied to numerical models. Results: Four of the 5 models tested ruptured at inflection points in the proximal and distal regions of the aneurysm sac and not at regions of maximum diameter. These findings agree with high stress regions computed numerically. Wall stress appears to be independent of wall thickness, with high stress occurring at regions of inflection regardless of wall thickness variations. Conclusion: According to these experimental and numerical findings, AAAs experience higher stresses at regions of inflection compared to regions of maximum diameter. Ruptures of the idealized silicone models occurred predominantly at the inflection points, as numerically predicted. Regions of inflection can be easily identified from basic 3-dimensional reconstruction; as ruptures appear to occur at inflection points, these findings may provide a useful insight into the clinical significance of inflection regions. This approach will be applied to patient-specific models in a future study. PMID:19642790

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