Sample records for create plants relieved

  1. Topical Pain Relievers May Cause Burns

    MedlinePlus

    ... and joint pain relievers containing the active ingredients menthol, methyl salicylate and capsaicin. These cases were uncovered ... of people who purchase these products, Tan notes. Menthol, methyl salicylate and capsaicin create sensations of local ...

  2. [Development of cough-relieving herbal teas].

    PubMed

    Puodziūniene, Gene; Janulis, Valdimaras; Milasius, Arvydas; Budnikas, Vytautas

    2005-01-01

    Cough-relieving medicinal herbs in tea are used from ancient times. Mucilage present in them or secretion produced under the influence of the active substances covers the oral and throat mucosa soothing its irritability and relieving dry, tiresome cough. It is known that the mixtures of medicinal herbs (Specias) have a complex influence on the human organism and the rational combination of medicinal herbs can improve their curative action and decrease the undesirable side effects. Having summarized the properties of those medicinal herbs we decided to create two formulations of cough-relieving herbal tea. The first formulation consists of marshmallow roots, liquorice roots and lime flowers, the second -- of marshmallow roots, Iceland moss and lime flowers. The methods for identification and assay of the active substances in the compounds were applied. The purity of the mixtures was regulated by limitation of the loss on drying, total ash, microbial contamination, contamination with radionuclides, heavy metals, pesticides and foreign matter. The expiry date of both cough-relieving herbal teas was approved to be 2 years.

  3. Plant stem cells as innovation in cosmetics.

    PubMed

    Moruś, Martyna; Baran, Monika; Rost-Roszkowska, Magdalena; Skotnicka-Graca, Urszula

    2014-01-01

    The stem cells thanks to their ability of unlimited division number or transformation into different cell types creating organs, are responsible for regeneration processes. Depending on the organism in which the stem cells exists, they divide to the plant or animal ones. The later group includes the stem cells existing in both embryo's and adult human's organs. It includes, among others, epidermal stem cells, located in the hair follicle relieves and also in its basal layers, and responsible for permanent regeneration of the epidermis. Temporary science looks for method suitable for stimulation of the epidermis stem cells, amongst the other by delivery of e.g., growth factors for proliferation that decrease with the age. One of the methods is the use of the plant cell culture technology, including a number of methods that should ensure growth of plant cells, issues or organs in the environment with the microorganism-free medium. It uses abilities of the different plant cells to dedifferentiation into stem cells and coming back to the pluripotent status. The extracts obtained this way from the plant stem cells are currently used for production of both common or professional care cosmetics. This work describes exactly impact of the plant stem cell extract, coming from one type of the common apple tree (Uttwiler Spätlauber) to human skin as one of the first plant sorts, which are used in cosmetology and esthetic dermatology.

  4. Creating an agricultural world order: regional plant protection problems and international phytopathology, 1878-1939.

    PubMed

    Castonguay, Stéphane

    2010-01-01

    Beginning in 1878 with the International Phylloxera Convention of Berne, international conventions have sought to relieve national agricultural industries from two specific burdens. First, by defining phytosanitary practices to be enforced by national plant protection services, these conventions attempted to prevent the introduction of plant diseases and pests into national territories from which they were previously absent. Second, by standardizing these practices - especially through the design of a unique certificate of inspection - the conventions attempted to eliminate barriers such as quarantines affection international agricultural trade. The succession of phytopathological conventions seemed to epitomize the coalescence of an international community against agricultural pests. What actually coalesced was bio-geopolitics wherein plant pathologists and economic entomologists from North America and the British Empire questioned the so-called internationality of the environmental and economic specificities of continental European agriculture, embodied in "international" conventions. Although an international phenomenon, the dissemination of agricultural pests provided opportunities for cooperation on a strictly regional albeit transnational basis that pitted bio-geopolitical spaces against each other. This article retraces the formation of these spaces by analyzing the deliberations of committees and congresses that gathered to define an international agricultural order based on the means to prevent the spread of plant diseases and pests.

  5. Nano-indentation used to study pyramidal slip in GaN single crystals

    NASA Astrophysics Data System (ADS)

    Krimsky, E.; Jones, K. A.; Tompkins, R. P.; Rotella, P.; Ligda, J.; Schuster, B. E.

    2018-02-01

    The nucleation and structure of dislocations created by the nano-indentation of GaN samples with dislocation densities ≈103, 106 or 109 ⊥/cm2 were studied in the interest of learning how dislocations can be created to relieve the mismatch strain in ternary nitride films grown on (0001) oriented binary nitride substrates. Using transmission electron microscopy and stress analyses to assist in interpreting the nano-indentation data, we determined that the pop-ins in the indenter load vs. penetration depth curves are created by an avalanche process at stresses well above the typical yield stress. The process begins by the homogeneous formation of a basal plane screw dislocation that triggers the formation of pyramidal and other basal plane dislocations that relieve the excess stored elastic energy. It appears that pyramidal slip can occur on either the {1122} or {0111} planes, as there is little resistance to the cross slip of screw dislocations.

  6. Relieving menstrual obstruction: surgical correction of vaginal agenesis.

    PubMed

    Schmitt, Jennifer J; Arora, Chetna; Gebhart, John B

    2016-04-01

    Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome includes vaginal agenesis with varied uterine development. The objective of this video is to illustrate our surgical technique to create a cervical and vaginal canal to relieve menstrual obstruction for a teenager with a functional uterus and vaginal agenesis. Using vaginal dissection and a mini laparotomy, a sound placed through the fundus of the uterus created an endocervical and vaginal channel to relieve her menstrual obstruction. A Foley catheter stented the cervical canal and a red rubber chest tube catheter stented the vagina until epithelization was achieved. No complications were encountered. The patient was examined with intermittent hysteroscopy with gentle dilation of the cervix. She had the red rubber catheter removed at 3 months, and she started using a small dilator. Her menses were suppressed with a gonadotropin releasing-hormone agonist allowing for complete healing. She is now 17. Her vaginal canal is well-epithelialized. Hysteroscopy confirmed a patent endocervical canal and uterine cavity. MRKH is rare. A small percentage of affected women has a functional endometrium requiring intervention for menstrual obstruction. Full vaginal reconstruction may be considered, but creation of a small canal to provide menstrual relief can be a temporary solution in those not desiring sexual function.

  7. I-55 integrated diversion traffic management benefit study.

    DOT National Transportation Integrated Search

    2014-11-01

    Traffic congestion, recurrent and non-recurrent, creates significant economic losses and environmental impacts. : Integrated Corridor Management (ICM) is a U.S.DOT research initiative that has been proven to effectively relieve : recurrent congestion...

  8. Production of cell wall-degrading enzymes by Aspergillus nidulans: a model system for fungal pathogenesis of plants.

    PubMed Central

    Dean, R A; Timberlake, W E

    1989-01-01

    The cell wall-degrading enzymes polygalacturonase and pectate lyase have been suggested to be crucial for penetration and colonization of plant tissues by some fungal pathogens. We have found that Aspergillus nidulans (= Emericella nidulans), a saprophytic Ascomycete, produces levels of these enzymes equal to those produced by soft-rotting Erwinia species. Induction of polygacturonase and pectate lyase in A. nidulans requires substrate and is completely repressed by glucose. Surprisingly, inoculation of excised plant tissues with A. nidulans conidia leads to formation of necrotic, water-soaked lesions within which the organism sporulates. Thus, A. nidulans has phytopathogenic potential. The release of glucose and other sugars from wounded tissues may repress pectolytic enzyme production and limit disease development. Therefore, we tested creA204, a mutation that relieves glucose repression of some A. nidulans carbon utilization enzymes, for its effect on production of pectolytic enzymes. creA204 failed to relieve catabolite repression of polygalacturonase or pectate lyase and had no effect on disease severity. PMID:2535501

  9. Opioid Abuse and Addiction

    MedlinePlus

    Opioids, sometimes called narcotics, are a type of drug. They include strong prescription pain relievers, such as ... tramadol. The illegal drug heroin is also an opioid. Some opioids are made from the opium plant, ...

  10. Herbal Remedies for Functional Dyspepsia and Traditional Iranian Medicine Perspective

    PubMed Central

    Babaeian, Mahmoud; Naseri, Mohsen; Kamalinejad, Mohammad; Ghaffari, Farzaneh; Emadi, Fatemeh; Feizi, Awat; Hosseini Yekta, Nafiseh; Adibi, Peyman

    2015-01-01

    Context: Functional dyspepsia (FD) is a functional gastro-intestinal disorder with high prevalence. Among various treatment options, treatment by complementary and alternative medicines especially herbal remedies also practiced. Traditional Iranian medicine (TIM), a valuable resource of valid applied studies of ancient Iranian scholars, recommends numerous medicinal plants to treat dyspepsia symptoms. In this study, through investigation of TIM references, we aimed to identify medicinal plants for treatment of digestion insufficiency. Evidence Acquisition: In this qualitative study, dyspepsia symptoms including fullness, early satiety, bloating, nausea, and belching were checked under reliable sources of traditional medicine. Then medicinal plants recommended for the treatment of the symptoms were extracted from the books. Likewise, for investigating the pharmacological properties of medicinal plants used for the relieving of dyspepsia symptoms, electronic databases such as PubMed, Scopus, Google Scholar and some Iranian databases like SID and IranMedex were employed. Results: The study yielded 105 plants from 37 families which could treat various dyspepsia symptoms; fifty-seven plants, mainly from Apiaceae, Lamiaceae, Amaryllidaceae and Zingiberaceae had digestive effects. In this research, based on the information in TIM reference texts, we obtained 58 plants effective for bloating, 40 for nausea, 37 for appetite loss and 7 for belching. In human clinical trials conducted on medicinal plants effective for FD symptoms, 7 single plants were used. Conclusions: Finding the medicinal plants effective on digestion insufficiency based on TIM could suggest a better strategy for the relieving of dyspepsia symptoms. Traditional Iranian medicine prescribes medicinal plants based on each patient’s personal characteristics and practices multiple target therapies. PMID:26734483

  11. Herbal Remedies for Functional Dyspepsia and Traditional Iranian Medicine Perspective.

    PubMed

    Babaeian, Mahmoud; Naseri, Mohsen; Kamalinejad, Mohammad; Ghaffari, Farzaneh; Emadi, Fatemeh; Feizi, Awat; Hosseini Yekta, Nafiseh; Adibi, Peyman

    2015-11-01

    Functional dyspepsia (FD) is a functional gastro-intestinal disorder with high prevalence. Among various treatment options, treatment by complementary and alternative medicines especially herbal remedies also practiced. Traditional Iranian medicine (TIM), a valuable resource of valid applied studies of ancient Iranian scholars, recommends numerous medicinal plants to treat dyspepsia symptoms. In this study, through investigation of TIM references, we aimed to identify medicinal plants for treatment of digestion insufficiency. In this qualitative study, dyspepsia symptoms including fullness, early satiety, bloating, nausea, and belching were checked under reliable sources of traditional medicine. Then medicinal plants recommended for the treatment of the symptoms were extracted from the books. Likewise, for investigating the pharmacological properties of medicinal plants used for the relieving of dyspepsia symptoms, electronic databases such as PubMed, Scopus, Google Scholar and some Iranian databases like SID and IranMedex were employed. The study yielded 105 plants from 37 families which could treat various dyspepsia symptoms; fifty-seven plants, mainly from Apiaceae, Lamiaceae, Amaryllidaceae and Zingiberaceae had digestive effects. In this research, based on the information in TIM reference texts, we obtained 58 plants effective for bloating, 40 for nausea, 37 for appetite loss and 7 for belching. In human clinical trials conducted on medicinal plants effective for FD symptoms, 7 single plants were used. Finding the medicinal plants effective on digestion insufficiency based on TIM could suggest a better strategy for the relieving of dyspepsia symptoms. Traditional Iranian medicine prescribes medicinal plants based on each patient's personal characteristics and practices multiple target therapies.

  12. Yerba Mate

    MedlinePlus

    Mate is a plant. The leaves are used to make medicine. Mate is used as a stimulant to relieve mental and physical tiredness ( ... diclofenac (Voltaren, Cataflam, others), ibuprofen (Advil, Motrin, others), naproxen (Anaprox, Naprosyn, others), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, ...

  13. Multihole Arc-Welding Orifice

    NASA Technical Reports Server (NTRS)

    Swaim, Benji D.

    1989-01-01

    Modified orifice for variable-polarity plasma-arc welding directs welding plume so it creates clean, even welds on both Inconel(R) and aluminum alloys. Includes eight holes to relieve back pressure in plasma. Quality of welds on ferrous and nonferrous alloys improved as result.

  14. [Effect of BSA on random amplified polymorphic DNA (RAPD) in plants].

    PubMed

    Bian, Cai-Miao; Li, Jun-Min; Jin, Ze-Xin; Ge, Ming-Ju

    2002-05-01

    Using Metasequoia glyptostroboides and Heptacodium miconioides DNA as templates,the effect of bovine serum albumin (BSA) on RAPD in plants was studied. The results showed that suitable concentrations of BSA used in Metasequoia glyptostroboides and Heptacodium miconioides RAPD were different, which were 0.6 microg/microl and 1 microg/microl, respectively. The inhibition of acetylated BSA on the amplification of plant RAPD could be relieved by BSA. BSA could reduce the dosage of Taq DNA polymerase.

  15. Workshop proceedings: U-bend tube cracking in steam generators

    NASA Astrophysics Data System (ADS)

    Shoemaker, C. E.

    1981-06-01

    A design to reduce the rate of tube failure in high pressure feedwater heaters, a number of failed drawn and stress relieved Monel 400 U-bend tubes removed from three high pressure feedwater heaters was examined. Steam extracted from the turbine is used to preheat the boiler feedwater in fossil fuel fired steam plants to improve thermal efficiency. This is accomplished in a series of heaters between the condenser hot well and the boiler. The heaters closest to the boiler handle water at high pressure and temperature. Because of the severe service conditions, high pressure feedwater heaters are frequently tubed with drawn and stress relieved Monel 400.

  16. My First Million: A Fantasy for the Future.

    ERIC Educational Resources Information Center

    Trede, Mildred

    1990-01-01

    The paper presents activities for improving students' literacy, oral communication, and thinking skills. Students brainstorm ideas for improving consumer products, think of ideas for starting a business, design an advertisement, estimate costs involved, create a demand for the product or service, and write a research paper on relieving stress.…

  17. Challenging Social Hierarchy: Playing with Oppositional Identities in Family Talk

    ERIC Educational Resources Information Center

    Bani-Shoraka, Helena

    2008-01-01

    This study examines how bilingual family members use language choice and language alternation as a local scheme of interpretation to distinguish different and often contesting social identities in interaction. It is argued that the playful creation of oppositional identities in interaction relieves the speakers from responsibility and creates a…

  18. Deconstruction Geography: A STEM Approach

    ERIC Educational Resources Information Center

    Gehlhar, Adam M.; Duffield, Stacy K.

    2015-01-01

    This article will define the engineering design process used to create an integrated curriculum at STEM Center Middle School, and it features the planning, implementation, and revision of the Deconstruction Geography unit. The Science Technology Engineering and Math (STEM) Center opened in the fall of 2009 as a way to relieve overcrowding at the…

  19. Experiment and simulation study on alkalis transfer characteristic during direct combustion utilization of bagasse.

    PubMed

    Liao, Yanfen; Cao, Yawen; Chen, Tuo; Ma, Xiaoqian

    2015-10-01

    Bagasse is utilized as fuel in the biggest biomass power plant of China, however, alkalis in the fuel created severe agglomeration and slagging problems. Alkalis transfer characteristic, agglomeration causes in engineering practice, additive improvement effects and mechanism during bagasse combustion were investigated via experiments and simulations. Only slight agglomeration occurs in ash higher than 800°C. Serious agglomeration in practical operation should be attributed to the gaseous alkalis evaporating at high temperature and condensing on the cooler grain surfaces in CFB. It can be speculated that ash caking can be avoided with temperature lower than 750°C and heating surface corrosion caused by alkali metal vapor can be alleviated with temperature lower than 850°C. Kaolin added into the bagasse has an apparent advantage over CaO additive both in enhancing ash fusion point and relieving alkali-chloride corrosion by locking alkalis in dystectic solid compounds over the whole temperature range. Copyright © 2015 Elsevier Ltd. All rights reserved.

  20. Analgesic Activity.

    PubMed

    2016-01-01

    Analgesics are agents which selectively relieve pain by acting in the CNS and peripheral pain mediators without changing consciousness. Analgesics may be narcotic or non-narcotic. The study of pain in animals raises ethical, philosophical, and technical problems. Both peripheral and central pain models are included to make the test more evident for the analgesic property of the plant. This chapter highlights methods such as hot plate and formalin and acetic acid-induced pain models to check the analgesic activity of medicinal plants.

  1. Effect of Inoculation with Glomus versiforme on Cadmium Accumulation, Antioxidant Activities and Phytochelatins of Solanum photeinocarpum

    PubMed Central

    Tan, Shi-Yun; Jiang, Qiu-Yun; Zhuo, Feng; Liu, Hui; Wang, Yu-Tao; Li, Shao-Shan; Ye, Zhi-Hong; Jing, Yuan-Xiao

    2015-01-01

    The plant growth, phosphate acquisition, Cd translocation, phytochelatins (PCs) production and antioxidant parameters [superoxide dismutase (SOD), catalase (CAT), guaiacol peroxidase (POD), ascorbate peroxidase (APX), glutathione reductase (GR), glutathione (GSH), ascorbate (ASA) and malonaldehyde (MDA)] were investigated in Cd-hyperaccumulator Solanum photeinocarpum inoculated with Glomus versiforme BGC GD01C (Gv) in Cd-added soils (0, 5, 10, 20, 40 mg Cd kg-1 soil). Mycorrhizal colonization rates were generally high (from 77% to 94%), and hardly affected by Cd. Gv colonization significantly enhanced P acquisition, growth and total Cd uptakes in both shoots and roots of S. photeinocarpum at all Cd levels. Meanwhile, Gv symbiosis significantly increased Cd concentration in the roots, and decreased Cd concentration in the shoots at all Cd levels, which indicates that Gv could promote phytostabilization by enhancing Cd accumulation in the roots to inhibit its translocation to shoots and the “dilution effects” linked to an increase in plant dry matter yield and a reduced Cd partitioning to shoots. Moreover, the improvement of CAT, POD and APX activities in the leaves of mycorrhizal plants infers that Gv symbiosis helped S. photeinocarpum to relieve oxidative damage to biomolecules in Cd-contaminated soil. The evident decline of MDA content in the leaves of mycorrhizal plants indicates that Gv symbiosis evidently improved antioxidant activities, and the enhancement of PCs production in the leaves of mycorrhizal plants suggests that Gv-inoculated plant may be more efficient to relieve Cd phytotoxicity. Therefore, the possible mechanisms of Cd phytotoxicity alleviation by Gv can be concluded as the decline of Cd concentration in the shoots and the improvement of P acquisition, PCs production and activities of CAT, POD, APX in mycorrhizal plants. PMID:26176959

  2. Nursing Process in Post Tonsillectomy Pain Diagnosis: A Systematic Review

    PubMed Central

    Soleymanifard, Fateme; Khademolhoseyni, Seyyed Mohamad; Nouri, Jamile Mokhtari

    2015-01-01

    Objective: Tonsillectomy is the most common surgery in the field of ENT. Pain is the most common post tonsillectomy complaint. Considering the importance of nursing cares in relieving post-surgery pain in general and post-tonsillectomy pain in particular, this study is conducted with the aim of presenting nursing process in post tonsillectomy pain diagnosis for decreasing loss of appropriate opportunities in nursing cares and achieving appropriate results in taking care of the patients. Methods: This study is a targeted systematic review focusing on “effective nursing measures in relieving children’s post tonsillectomy pain”. The main stages of searching strategy included searching in electronic sources of Latin databases; Pub Med, Science Direct, and EMBASE and Persian databases; SID, Iran medex, ISC to find published articles from 2009 to 2014. In the end, final synthesis was done on eight articles in English. Findings: Effective nursing measurements for relieving post tonsillectomy pain include: decreasing children’s anxiety through children and their families’ psychological preparation by nurses and other caregivers, using cold compress to reduce neck and jaw pain, presenting distraction techniques, offering fluids and cold foods immediately in the period after surgery, creating a comfortable environment for the children, avoiding too much of talking and adequate sleep. Conclusion: It is recommended to the nursing managers and nurses to perform cares achieved from this systematic review to achieve appropriate results in relieving post tonsillectomy pain. PMID:25560345

  3. Trends in the Distribution of Opioids in Puerto Rico, 1999-2013.

    PubMed

    El Burai Félix, Sausan; Mack, Karin A; Jones, Christopher M

    2016-09-01

    Limited information has been published about opioid prescribing practices in Puerto Rico. The objective of this study was to create baseline trends of opioids distributed over a period of fourteen years in Puerto Rico. We examined data from the U.S. Drug Enforcement Administration's Automation of Reports and Consolidated Orders System (ARCOS) for the period 1999-2013. ARCOS data reflects the amount of controlled substances legally dispensed. Analyses include the distribution of opioids (in morphine milligram equivalent kg per 10,000 persons) by year and entity (pharmacy, hospital, practitioner). The distribution of four drugs (fentanyl, hydromorphone, methadone, oxycodone) increased over 100% between 1999 and 2013. The distribution of two drugs (hydrocodone and meperidine) declined between 1999 and 2013. Oxycodone distribution grew from 0.13 MME kg grams per 10,000 persons in 1999 to 0.29 MME kg in 2013. ARCOS data showed that the overall amount of opioid pain relievers distributed in Puerto Rico increased by 68% between 1999 and 2013. Currently, prescription opioid pain reliever overdose deaths in Puerto Rico do not appear to be skyrocketing as they are in the mainland U.S. However, the ongoing problem with prescription opioid pain reliever overdoses in certain areas should serve as a warning to monitor consumption of opioid pain relievers, as well as changes in prescription drug abuse, overdoses, and deaths.

  4. A Guide for Technical Authors: Creating Texts That Are Clear and Effective

    DTIC Science & Technology

    2010-06-01

    and order the entire text into chapters? Paying attention to these points will give your entire documents a tightness and lucidity . It’s easiest to...relieves them of the need to proofread their writing carefully. Too many authors who would never dream of using the word Graham in expressing a measure

  5. Can transmyocardial CO2 laser channels supply nutritive blood flow into adjacent myocardium?

    NASA Astrophysics Data System (ADS)

    Kohmoto, Takushi; Fisher, Peter E.; DeRosa, Carolyn; Smith, Craig R.; Burkhoff, Daniel

    1996-05-01

    Clinical reports of transmyocardial laser revascularization (TMLR) suggest that this procedure is effective in relieving angina. However, experimental evidence of nutritive blood flow through the TMLR channels is not available. The purpose of this study was to test whether blood could flow through the TMLR channels created with the carbon-dioxide laser.

  6. CELLULOSE SYNTHASE INTERACTIVE1 Is Required for Fast Recycling of Cellulose Synthase Complexes to the Plasma Membrane in Arabidopsis

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lei, Lei; Singh, Abhishek; Bashline, Logan

    Plants are constantly subjected to various biotic and abiotic stresses and have evolved complex strategies to cope with these stresses. For example, plant cells endocytose plasma membrane material under stress and subsequently recycle it back when the stress conditions are relieved. Cellulose biosynthesis is a tightly regulated process that is performed by plasma membrane-localized cellulose synthase (CESA) complexes (CSCs). However, the regulatory mechanism of cellulose biosynthesis under abiotic stress has not been well explored. In this study, we show that small CESA compartments (SmaCCs) or microtubule-associated cellulose synthase compartments (MASCs) are critical for fast recovery of CSCs to the plasmamore » membrane after stress is relieved in Arabidopsis thaliana. This SmaCC/MASC-mediated fast recovery of CSCs is dependent on CELLULOSE SYNTHASE INTERACTIVE1 (CSI1), a protein previously known to represent the link between CSCs and cortical microtubules. Independently, AP2M, a core component in clathrin-mediated endocytosis, plays a role in the formation of SmaCCs/MASCs. Together, our study establishes a model in which CSI1-dependent SmaCCs/MASCs are formed through a process that involves endocytosis, which represents an important mechanism for plants to quickly regulate cellulose synthesis under abiotic stress.« less

  7. Evaluation of drug interaction potential of Labisia pumila (Kacip Fatimah) and its constituents

    USDA-ARS?s Scientific Manuscript database

    Labisia pumila (Kacip Fatimah) is a popular herb in Malaysia that has been traditionally used in a number of women's health applications such as to improve libido, relieve postmenopausal symptoms, and to facilitate or hasten delivery in childbirth. In addition, the constituents of this plant have be...

  8. 27 CFR 24.158 - Extent of relief.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Extent of relief. 24.158 Section 24.158 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT..., until all tax is fully paid. (d) Wine vinegar plant bond. The surety will be relieved of liability for...

  9. An Internet Application To Relieve Constraints in the Flow of Technical Information--The Virtual Technology Market (VTM).

    ERIC Educational Resources Information Center

    Beverly, James E.; Xue, Lan; Lee, Chung-Shing

    1996-01-01

    Reports on the use of the Internet and World Wide Web as a virtual technology market (VTM) for information and technology transfer. The project focuses on creating awareness of technology demand (problems) and linking it to technology supply (solutions) in the field of particle technology and multiphase processes in the chemical industry. Benefits…

  10. Top Textbooks on Reserve: Creating, Promoting, and Assessing a Program to Help Meet Students' Need for Affordable Textbooks

    ERIC Educational Resources Information Center

    Thompson, Hilary H.; Cotton, Jennifer E. M.

    2017-01-01

    In Fall 2014 the University of Maryland Libraries launched a textbook reserves program to help relieve the burden of high textbook costs on students. Although its initial performance was lackluster, workflow refinements and expanded promotion greatly improved usage, resulting in a tenfold increase in circulation and expansion of the program. This…

  11. Puerarin blocks the signaling transmission mediated by P2X3 in SG and DRG to relieve myocardial ischemic damage.

    PubMed

    Liu, Shuangmei; Zhang, Chunping; Shi, Qingming; Li, Guilin; Song, Miaomiao; Gao, Yun; Xu, Changshui; Xu, Hong; Fan, Bo; Yu, Shicheng; Zheng, Chaoran; Zhu, Qicheng; Wu, Bing; Peng, Lichao; Xiong, Huangui; Wu, Qin; Liang, Shangdong

    2014-02-01

    P2X₃ receptors in stellate ganglia (SG) and cervical dorsal root ganglia (DRG) neurons are involved in sympathoexcitatory reflex induced by myocardial ischemic damage. Puerarin, a major active ingredient extracted from the traditional Chinese plant medicine Ge-gen, has been widely used in treatment of myocardial and cerebral ischemia. The present study is aimed to observe the effects of puerarin on the signaling transmission mediated by P2X₃ receptor in SG and DRG after myocardial ischemic damage. Our results showed that systolic blood pressure and heart rate increased, and the expression levels of P2X₃ mRNA and protein in SG and DRG were up-regulated after myocardial ischemic damage. Puerarin reduced systolic blood pressure and heart rate, relieved pain and decreased up-regulated expression of P2X₃ mRNA and protein in SG and DRG after myocardial ischemia. Puerarin inhibited the up-regulated ATP-activated currents in DRG neurons after myocardial ischemia. Thus, puerarin can relieve myocardial ischemic damage through blocking the P2X₃ signaling transmission and then depressed the aggravated sympathoexcitatory reflex. Copyright © 2014 Elsevier Inc. All rights reserved.

  12. The physical effects of aromatherapy in alleviating work-related stress on elementary school teachers in taiwan.

    PubMed

    Liu, Shing-Hong; Lin, Tzu-Hsin; Chang, Kang-Ming

    2013-01-01

    People use aromatherapy to relieve the symptoms of physical and psychological stress. However, previous studies have not precisely clarified a scientific basis for the beneficial effects of aromatherapy. Therefore, the overall purpose of this study was to elucidate the beneficial effect of aromatherapy in relieving work-related stress. Twenty-nine elementary school teachers from Taiwan participated in this study. The experimental procedures comprised 2 phases. First, we verified the effect of aromatherapy by conducting 2 blind tests. We used natural bergamot essential oil extracted from plants and synthesized a chemical essential oil as the placebo to do the aromatherapy. Second, we analyzed the performance of the aromatherapy treatment on the teachers who had various workloads. We measured the teachers' heart rate variability to evaluate their autonomic nervous system activity. The results show that only the natural bergamot essential oil had an effect and that the aromatherapy treatment relieved work-related stress of teachers with various workloads. However, the aromatherapy treatment had a weak effect on young teachers who had a heavy workload. Moreover, the aromatherapy treatment exhibited no effect on teachers who belong to the abnormal body mass index subgroup having a heavy workload.

  13. The Physical Effects of Aromatherapy in Alleviating Work-Related Stress on Elementary School Teachers in Taiwan

    PubMed Central

    Liu, Shing-Hong; Lin, Tzu-Hsin; Chang, Kang-Ming

    2013-01-01

    People use aromatherapy to relieve the symptoms of physical and psychological stress. However, previous studies have not precisely clarified a scientific basis for the beneficial effects of aromatherapy. Therefore, the overall purpose of this study was to elucidate the beneficial effect of aromatherapy in relieving work-related stress. Twenty-nine elementary school teachers from Taiwan participated in this study. The experimental procedures comprised 2 phases. First, we verified the effect of aromatherapy by conducting 2 blind tests. We used natural bergamot essential oil extracted from plants and synthesized a chemical essential oil as the placebo to do the aromatherapy. Second, we analyzed the performance of the aromatherapy treatment on the teachers who had various workloads. We measured the teachers' heart rate variability to evaluate their autonomic nervous system activity. The results show that only the natural bergamot essential oil had an effect and that the aromatherapy treatment relieved work-related stress of teachers with various workloads. However, the aromatherapy treatment had a weak effect on young teachers who had a heavy workload. Moreover, the aromatherapy treatment exhibited no effect on teachers who belong to the abnormal body mass index subgroup having a heavy workload. PMID:24228065

  14. High Throughput In vivo Analysis of Plant Leaf Chemical Properties Using Hyperspectral Imaging

    PubMed Central

    Pandey, Piyush; Ge, Yufeng; Stoerger, Vincent; Schnable, James C.

    2017-01-01

    Image-based high-throughput plant phenotyping in greenhouse has the potential to relieve the bottleneck currently presented by phenotypic scoring which limits the throughput of gene discovery and crop improvement efforts. Numerous studies have employed automated RGB imaging to characterize biomass and growth of agronomically important crops. The objective of this study was to investigate the utility of hyperspectral imaging for quantifying chemical properties of maize and soybean plants in vivo. These properties included leaf water content, as well as concentrations of macronutrients nitrogen (N), phosphorus (P), potassium (K), magnesium (Mg), calcium (Ca), and sulfur (S), and micronutrients sodium (Na), iron (Fe), manganese (Mn), boron (B), copper (Cu), and zinc (Zn). Hyperspectral images were collected from 60 maize and 60 soybean plants, each subjected to varying levels of either water deficit or nutrient limitation stress with the goal of creating a wide range of variation in the chemical properties of plant leaves. Plants were imaged on an automated conveyor belt system using a hyperspectral imager with a spectral range from 550 to 1,700 nm. Images were processed to extract reflectance spectrum from each plant and partial least squares regression models were developed to correlate spectral data with chemical data. Among all the chemical properties investigated, water content was predicted with the highest accuracy [R2 = 0.93 and RPD (Ratio of Performance to Deviation) = 3.8]. All macronutrients were also quantified satisfactorily (R2 from 0.69 to 0.92, RPD from 1.62 to 3.62), with N predicted best followed by P, K, and S. The micronutrients group showed lower prediction accuracy (R2 from 0.19 to 0.86, RPD from 1.09 to 2.69) than the macronutrient groups. Cu and Zn were best predicted, followed by Fe and Mn. Na and B were the only two properties that hyperspectral imaging was not able to quantify satisfactorily (R2 < 0.3 and RPD < 1.2). This study suggested the potential usefulness of hyperspectral imaging as a high-throughput phenotyping technology for plant chemical traits. Future research is needed to test the method more thoroughly by designing experiments to vary plant nutrients individually and cover more plant species, genotypes, and growth stages. PMID:28824683

  15. High Throughput In vivo Analysis of Plant Leaf Chemical Properties Using Hyperspectral Imaging.

    PubMed

    Pandey, Piyush; Ge, Yufeng; Stoerger, Vincent; Schnable, James C

    2017-01-01

    Image-based high-throughput plant phenotyping in greenhouse has the potential to relieve the bottleneck currently presented by phenotypic scoring which limits the throughput of gene discovery and crop improvement efforts. Numerous studies have employed automated RGB imaging to characterize biomass and growth of agronomically important crops. The objective of this study was to investigate the utility of hyperspectral imaging for quantifying chemical properties of maize and soybean plants in vivo . These properties included leaf water content, as well as concentrations of macronutrients nitrogen (N), phosphorus (P), potassium (K), magnesium (Mg), calcium (Ca), and sulfur (S), and micronutrients sodium (Na), iron (Fe), manganese (Mn), boron (B), copper (Cu), and zinc (Zn). Hyperspectral images were collected from 60 maize and 60 soybean plants, each subjected to varying levels of either water deficit or nutrient limitation stress with the goal of creating a wide range of variation in the chemical properties of plant leaves. Plants were imaged on an automated conveyor belt system using a hyperspectral imager with a spectral range from 550 to 1,700 nm. Images were processed to extract reflectance spectrum from each plant and partial least squares regression models were developed to correlate spectral data with chemical data. Among all the chemical properties investigated, water content was predicted with the highest accuracy [ R 2 = 0.93 and RPD (Ratio of Performance to Deviation) = 3.8]. All macronutrients were also quantified satisfactorily ( R 2 from 0.69 to 0.92, RPD from 1.62 to 3.62), with N predicted best followed by P, K, and S. The micronutrients group showed lower prediction accuracy ( R 2 from 0.19 to 0.86, RPD from 1.09 to 2.69) than the macronutrient groups. Cu and Zn were best predicted, followed by Fe and Mn. Na and B were the only two properties that hyperspectral imaging was not able to quantify satisfactorily ( R 2 < 0.3 and RPD < 1.2). This study suggested the potential usefulness of hyperspectral imaging as a high-throughput phenotyping technology for plant chemical traits. Future research is needed to test the method more thoroughly by designing experiments to vary plant nutrients individually and cover more plant species, genotypes, and growth stages.

  16. ε Subunit of Bacillus subtilis F1-ATPase Relieves MgADP Inhibition

    PubMed Central

    Mizumoto, Junya; Kikuchi, Yuka; Nakanishi, Yo-Hei; Mouri, Naoto; Cai, Anrong; Ohta, Tokushiro; Haruyama, Takamitsu; Kato-Yamada, Yasuyuki

    2013-01-01

    MgADP inhibition, which is considered as a part of the regulatory system of ATP synthase, is a well-known process common to all F1-ATPases, a soluble component of ATP synthase. The entrapment of inhibitory MgADP at catalytic sites terminates catalysis. Regulation by the ε subunit is a common mechanism among F1-ATPases from bacteria and plants. The relationship between these two forms of regulatory mechanisms is obscure because it is difficult to distinguish which is active at a particular moment. Here, using F1-ATPase from Bacillus subtilis (BF1), which is strongly affected by MgADP inhibition, we can distinguish MgADP inhibition from regulation by the ε subunit. The ε subunit did not inhibit but activated BF1. We conclude that the ε subunit relieves BF1 from MgADP inhibition. PMID:23967352

  17. Thermodynamic Analyses of the LCLS-II Cryogenic Distribution System

    DOE PAGES

    Dalesandro, Andrew; Kaluzny, Joshua; Klebaner, Arkadiy

    2016-12-29

    The Linac Coherent Light Source (LCLS) at Stanford Linear Accelerator Center (SLAC) is in the process of being upgraded to a superconducting radio frequency (SRF) accelerator and renamed LCLS-II. This upgrade requires thirty-five 1.3 GHz SRF cryomodules (CM) and two 3.9 GHz CM. A cryogenic distribution system (CDS) is in development by Fermi National Accelerator Laboratory to interconnect the CM Linac with the cryogenic plant (CP). The CDS design utilizes cryogenic helium to support the CM operations with a high temperature thermal shield around 55 K, a low temperature thermal intercepts around 5 K, and a SRF cavity liquid heliummore » supply and sub-atmospheric vapor return both around 2 K. Additionally the design must accommodate a Linac consisting of two parallel cryogenic strings, supported by two independent CP utilizing CDS components such as distribution boxes, transfer lines, feed caps and endcaps. In this paper, we describe the overall layout of the cryogenic distribution system and the major thermodynamic factors which influence the CDS design including heat loads, pressure drops, temperature profiles, and pressure relieving requirements. In addition the paper describes how the models are created to perform the analyses.« less

  18. Civil markets for buoyant heavy-lift vehicles

    NASA Technical Reports Server (NTRS)

    Mettam, P. J.; Hansen, D.; Ardema, M. D.

    1981-01-01

    Worldwide civil markets for heavy lift airships were investigated. Substantial potential market demand was identified for payloads of from 13 to 800 tons. The largest markets appear to be in applications to relieve port congestion, construction of power generating plants, and, most notably, logging. Because of significant uncertainties both in vehicle and market characteristics, further analysis will be necessary to verify the identified market potential of heavy lift airship concepts.

  19. United States-Canada Trade and Economic Relationship: Prospects and Challenges

    DTIC Science & Technology

    2009-05-13

    capita income gap has proven worrisome to Canadian policymakers as it raises questions about Canadian productivity and competitiveness . In terms of...Canada suffers from productivity problems in other sectors of its economy, its automotive plants are among the most competitive in North America...the U.S. dollar in 2007-8. Another major competitive advantage is Canada’s national health system, which reportedly relieves Canadian automakers of

  20. The clinical utility of testicular prosthesis placement in children with genital and testicular disorders

    PubMed Central

    2014-01-01

    Testicular prosthesis placement is a useful important adjunctive reconstructive therapy for managing children with testicular loss or absence. Though these prostheses are functionless, experience has shown that they are extremely helpful in creating a more normal male body image and in preventing/relieving psychological stress in males with a missing testicle. With attention to details of implant technique, excellent cosmetic results can be anticipated in simulating a normal appearing scrotum. PMID:26816795

  1. Effect of wing flexibility on the experimental aerodynamic characteristics of an oblique wing

    NASA Technical Reports Server (NTRS)

    Hopkins, E. J.; Yee, S. C.

    1977-01-01

    A solid-aluminum oblique wing was designed to deflect considerably under load so as to relieve the asymmetric spanwise stalling that is characteristic of this type of wing by creating washout on the trailing wing panel and washin on the leading wing panel. Experimental forces, and pitching, rolling and yawing moments were measured with the wing mounted on a body of revolution. In order to vary the dynamic pressure, measurements were made at several unit Reynolds numbers, and at Mach numbers. The wing was investigated when unswept (at subsonic Mach numbers only) and when swept 45 deg, 50 deg, and 60 deg. The wing was straight tapered in planform, had an aspect ratio of 7.9 (based on the unswept span), and a profile with a maximum thickness of 4 percent chord. The results substantiate the concept that an oblique wing designed with the proper amount of flexibility self relieves itself of asymmetric spanwise stalling and the associated nonlinear moment curves.

  2. Nutritional, Medicinal and Toxicological Attributes of Star-Fruits (Averrhoa carambola L.): A Review

    PubMed Central

    Muthu, Narmataa; Lee, Su Yin; Phua, Kia Kien; Bhore, Subhash Janardhan

    2016-01-01

    Plants are very complex organisms that produce medicinally important natural products. The Star-fruit producing plant (Averrhoa carambola L.) is a species of woody plant in the family Oxalidaceae native to the Philippines, Indonesia, Malaysia, Vietnam, India, Bangladesh and Sri Lanka; but, cultivated in many parts of the world. Star-fruits are popular tropical fruits and used commonly in Ayurvedic and Traditional Chinese Medicines (TCM) in India, China, and Brazil to relieve ailments such as chronic headache, fever, cough, gastro-enteritis, diarrhoea, ringworm infections, and skin inflammations. However, this fruit contains high amount of oxalate, which is hazardous for uremic patients, and caramboxin (CBX), which is neurotoxic. The aim of this review is to highlight the nutritional, medicinal and toxicological traits of the star-fruits. PMID:28405126

  3. Nutritional, Medicinal and Toxicological Attributes of Star-Fruits (Averrhoa carambola L.): A Review.

    PubMed

    Muthu, Narmataa; Lee, Su Yin; Phua, Kia Kien; Bhore, Subhash Janardhan

    2016-01-01

    Plants are very complex organisms that produce medicinally important natural products. The Star-fruit producing plant (Averrhoa carambola L.) is a species of woody plant in the family Oxalidaceae native to the Philippines, Indonesia, Malaysia, Vietnam, India, Bangladesh and Sri Lanka; but, cultivated in many parts of the world. Star-fruits are popular tropical fruits and used commonly in Ayurvedic and Traditional Chinese Medicines (TCM) in India, China, and Brazil to relieve ailments such as chronic headache, fever, cough, gastro-enteritis, diarrhoea, ringworm infections, and skin inflammations. However, this fruit contains high amount of oxalate, which is hazardous for uremic patients, and caramboxin (CBX), which is neurotoxic. The aim of this review is to highlight the nutritional, medicinal and toxicological traits of the star-fruits.

  4. Interaction between control and design of a SHARON reactor: economic considerations in a plant-wide (BSM2) context.

    PubMed

    Volcke, E I P; van Loosdrecht, M C M; Vanrolleghem, P A

    2007-01-01

    The combined SHARON-Anammox process is a promising technique for nitrogen removal from wastewater streams with high ammonium concentrations. It is typically applied to sludge digestion reject water, in order to relieve the activated sludge tanks, to which this stream is typically recycled. This contribution assesses the impact of the applied control strategy in the SHARON-reactor, both on the effluent quality of the subsequent Anammox reactor as well as on the plant-wide level by means of an operating cost index. Moreover, it is investigated to which extent the usefulness of a certain control strategy depends on the reactor design (volume). A simulation study is carried out using the plant-wide Benchmark Simulation Model no. 2 (BSM2), extended with the SHARON and Anammox processes. The results reveal a discrepancy between optimizing the reject water treatment performance and minimizing plant-wide operating costs.

  5. Phytodermatitis caused by Ceratocephalus falcatus (Ranunculacea).

    PubMed

    Karaca, Semsettin; Kulac, Mustafa; Kucuker, Hudaverdi

    2005-01-01

    Ceratocephalus falcatus is a member of Ranunculacea family that forms part of the flora of the Sinanpasa and Dinar regions of Afyon city in Turkey. Ceratocephalus falcatus has laxative properties and has been used for treating hemorrhoids, rheumatismal diseases and wounds. Here, a case of phytodermatitis caused by this remedy used for relieving knee pain is presented. This plant should be kept in mind when a case of phytodermatitis with vesicles or bullae presents at clinics.

  6. Effect of stimulation by foliage plant display images on prefrontal cortex activity: a comparison with stimulation using actual foliage plants.

    PubMed

    Igarashi, Miho; Song, Chorong; Ikei, Harumi; Miyazaki, Yoshifumi

    2015-01-01

    Natural scenes like forests and flowers evoke neurophysiological responses that can suppress anxiety and relieve stress. We examined whether images of natural objects can elicit neural responses similar to those evoked by real objects by comparing the activation of the prefrontal cortex during presentation of real foliage plants with a projected image of the same foliage plants. Oxy-hemoglobin concentrations in the prefrontal cortex were measured using time-resolved near-infrared spectroscopy while the subjects viewed the real plants or a projected image of the same plants. Compared with a projected image of foliage plants, viewing the actual foliage plants significantly increased oxy-hemoglobin concentrations in the prefrontal cortex. However, using the modified semantic differential method, subjective emotional response ratings ("comfortable vs. uncomfortable" and "relaxed vs. awakening") were similar for both stimuli. The frontal cortex responded differently to presentation of actual plants compared with images of these plants even when the subjective emotional response was similar. These results may help explain the physical and mental health benefits of urban, domestic, and workplace foliage. © 2014 The Authors. Journal of Neuroimaging published by the American Society of Neuroimaging.

  7. Mindful Self-Hypnosis for Self-Care: An Integrative Model and Illustrative Case Example.

    PubMed

    Elkins, Gary R; Roberts, R Lynae; Simicich, Lauren

    2018-07-01

    The combination of mindfulness and self-hypnosis could provide a tool that is easily implemented by individuals who want to care for their well-being in times of high stress. Each discipline has been shown to be effective in relieving stress, and integration could further facilitate change while creating a tool that is highly accessible. There are many similarities between the two practices, such as focusing of attention and the emphasis on mind-body connection. However, important distinctions in psychological (e.g., self-monitoring) and neural (e.g., functional connectivity) elements are noted. A theory of how integrated mindful self-hypnosis may create change is presented. An illustrative case example of mindful self-hypnosis practice and a self-hypnosis transcript are provided.

  8. Ethnopharmacological Survey of Plants Used in the Traditional Treatment of Gastrointestinal Pain, Inflammation and Diarrhea in Africa: Future Perspectives for Integration into Modern Medicine

    PubMed Central

    Stark, Timo D.; Mtui, Dorah J.; Balemba, Onesmo B.

    2013-01-01

    Simple Summary This review provides an inventory of numerous plant species used as traditional remedies for pain and diarrhea in Africa. Africa can emulate advances in traditional Chinese medicine through research, commercialization, teaching traditional medicine in medical schools, and incorporating botanical products in treating veterinary and human patients. Prioritized research of plant species with proven folklore in treating pain and diarrhea using high throughput screening to identify and test bioactive compounds to verify their effectiveness, mechanisms of action and safety and translational research are needed to facilitate these advances and the integration of traditional African botanical preparations for treating pain and gastrointestinal disorders into western medicine. Abstract There is a growing need to find the most appropriate and effective treatment options for a variety of painful syndromes, including conditions affecting the gastrointestinal tract, for treating both veterinary and human patients. The most successful regimen may come through integrated therapies including combining current and novel western drugs with acupuncture and botanical therapies or their derivatives. There is an extensive history and use of plants in African traditional medicine. In this review, we have highlighted botanical remedies used for treatment of pain, diarrheas and inflammation in traditional veterinary and human health care in Africa. These preparations are promising sources of new compounds comprised of flavonoids, bioflavanones, xanthones, terpenoids, sterols and glycosides as well as compound formulas and supplements for future use in multimodal treatment approaches to chronic pain, gastrointestinal disorders and inflammation. The advancement of plant therapies and their derivative compounds will require the identification and validation of compounds having specific anti-nociceptive neuromodulatory and/or anti-inflammatory effects. In particular, there is need for the identification of the presence of compounds that affect purinergic, GABA, glutamate, TRP, opioid and cannabinoid receptors, serotonergic and chloride channel systems through bioactivity-guided, high-throughput screening and biotesting. This will create new frontiers for obtaining novel compounds and herbal supplements to relieve pain and gastrointestinal disorders, and suppress inflammation. PMID:26487315

  9. Sleep, Stress & Relaxation: Rejuvenate Body & Mind

    Cancer.gov

    Sleep, Stress & Relaxation: Rejuvenate Body & Mind; Relieve Stress; best ways to relieve stress; best way to relieve stress; different ways to relieve stress; does smoking relieve stress; does tobacco relieve stress; how can I relieve stress; how can you relieve stress; how do I relieve stress; reduce stress; does smoking reduce stress; how can I reduce stress; how to reduce stress; reduce stress; reduce stress levels; reducing stress; smoking reduce stress; smoking reduces stress; stress reducing techniques; techniques to reduce stress; stress relief; best stress relief; natural stress relief; need stress relief; relief for stress; relief from stress; relief of stress; smoking and stress relief; smoking for stress relief; smoking stress relief; deal with stress; dealing with stress; dealing with anger; dealing with stress; different ways of dealing with stress; help dealing with stress; how to deal with anger; how to deal with stress; how to deal with stress when quitting smoking; stress management; free stress management; how can you manage stress; how do you manage stress; how to manage stress; manage stress; management of stress; management stress; managing stress; strategies for managing stress; coping with stress; cope with stress; copeing with stress; coping and stress; coping skills for stress; coping strategies for stress; coping strategies with stress; coping strategy for stress; coping with stress; coping with stress and anxiety; emotional health; emotional health; emotional health article; emotional health articles; deep relaxation; deep breathing relaxation techniques; deep muscle relaxation; deep relaxation; deep relaxation meditation; deep relaxation technique; deep relaxation techniques; meditation exercises; mindful exercises; mindful meditation exercises; online relaxation exercises; relaxation breathing exercises; relaxation exercise; relaxation exercises; stress relaxation; methods of relaxation for stress; relax stress; relax techniques stress; relaxation and stress; relaxation and stress reduction; relaxation and stress relief; relaxation exercises for stress; relaxation for stress; mind; mind relaxation; mind relaxation techniques; mindful meditation; mindful meditation techniques; mindfulness; mindful meditation; mindful meditation techniques; relax your mind; relieve stress; best ways to relieve stress; help relieve stress; how can I relieve stress; how can we relieve stress; how can you relieve stress; how do I relieve stress; how do you relieve stress; how relieve stress; cope with stress; cope with stress; coping strategies for stress; coping with stress; how to cope with stress; ways of coping with stress; ways to cope with stress; trouble sleeping; having trouble sleeping; i have trouble sleeping; sleep trouble; sleeping trouble; trouble getting to sleep; trouble sleeping; trouble sleeping at night; sleep better; better sleep; help me sleep better; how can I get better sleep; how to sleep better; sleep better

  10. Structure of the novel monomeric glyoxalase I from Zea mays

    PubMed Central

    Turra, Gino L.; Agostini, Romina B.; Fauguel, Carolina M.; Presello, Daniel A.; Andreo, Carlos S.; González, Javier M.; Campos-Bermudez, Valeria A.

    2015-01-01

    The glyoxalase system is ubiquitous among all forms of life owing to its central role in relieving the cell from the accumulation of methylglyoxal, a toxic metabolic byproduct. In higher plants, this system is upregulated under diverse metabolic stress conditions, such as in the defence response to infection by pathogenic microorganisms. Despite their proven fundamental role in metabolic stresses, plant glyoxalases have been poorly studied. In this work, glyoxalase I from Zea mays has been characterized both biochemically and structurally, thus reporting the first atomic model of a glyoxalase I available from plants. The results indicate that this enzyme comprises a single polypeptide with two structurally similar domains, giving rise to two lateral concavities, one of which harbours a functional nickel(II)-binding active site. The putative function of the remaining cryptic active site remains to be determined. PMID:26457425

  11. Structure of the novel monomeric glyoxalase I from Zea mays.

    PubMed

    Turra, Gino L; Agostini, Romina B; Fauguel, Carolina M; Presello, Daniel A; Andreo, Carlos S; González, Javier M; Campos-Bermudez, Valeria A

    2015-10-01

    The glyoxalase system is ubiquitous among all forms of life owing to its central role in relieving the cell from the accumulation of methylglyoxal, a toxic metabolic byproduct. In higher plants, this system is upregulated under diverse metabolic stress conditions, such as in the defence response to infection by pathogenic microorganisms. Despite their proven fundamental role in metabolic stresses, plant glyoxalases have been poorly studied. In this work, glyoxalase I from Zea mays has been characterized both biochemically and structurally, thus reporting the first atomic model of a glyoxalase I available from plants. The results indicate that this enzyme comprises a single polypeptide with two structurally similar domains, giving rise to two lateral concavities, one of which harbours a functional nickel(II)-binding active site. The putative function of the remaining cryptic active site remains to be determined.

  12. Patterns of analgesic use to relieve tooth pain among residents in British Columbia, Canada

    PubMed Central

    2017-01-01

    The use of prescription opioids has increased dramatically in Canada in recent decades. This rise in opioid prescriptions has been accompanied by increasing rates of opioid-related abuse and addiction, creating serious public health challenges in British Columbia (BC), one of Canada's most populated provinces. Our study explores the relationship between dental pain and prescription opioid use among residents in BC. We used data from the 2003 Canadian Community Health Survey (CCHS), which asked respondents about their use of specific analgesic medications, including opioids, and their history of tooth pain in the past month. We used logistic regression, controlling for potential confounding variables, to identify the predictive value of socioeconomic factors, oral health-related variables, and dental care utilization indicators. The Relative Index of Inequality (RII) was calculated to assess the magnitude of socioeconomic inequalities in the use of particular analgesics by incorporating income-derived ridit values into a binary logistic regression model. Our results showed that conventional non-opioid based analgesics (such as aspirin or Tylenol) and opioids were more likely to be used by those who had experienced a toothache in the past month than those who did not report experiencing a toothache. The use of non-opioid painkillers to relieve tooth pain was associated with more recent and more frequent dental visits, better self-reported oral health, and a greater income. Conversely, a lower household income was associated with a preference for opioid use to relieve tooth pain. The RII for recent opioid use and conventional painkiller use were 2.06 (95% CI: 1.75–2.37) and 0.62 (95% CI: 0.35–0.91), respectively, among those who experienced recent tooth pain, suggesting that adverse socioeconomic conditions may influence the need for opioid analgesics to relieve dental pain. We conclude that programs and policies targeted at improving the dental health of the poor may help to reduce the use of prescription opioids, thereby narrowing health inequalities within the broader society. PMID:28459825

  13. Manoeuvring along the edge of breathlessness: an ethnographic case study of two nurses.

    PubMed

    Jellington, Maria Omel; Overgaard, Dorthe; Sørensen, Erik Elgaard

    2016-01-01

    There appears to be divergence between nurses' and patients' perceptions of dyspnoea onset and on how help should be given. This may affect how nurses understand and assess their patients' anxiety and the severity of dyspnoea, potentially diminishing their chances of relieving patients' dyspnoea. The aim of this study was to explore nurse-patient interaction in situations where patients with chronic obstructive pulmonary disease are experiencing acute or worsened dyspnoea in a hospital setting. An ethnographic study using participant observation of two nurses' interactions with six patients, followed by qualitative in-depth interviews with the nurses. Data were analysed in three steps. First, they were coded for identification of preliminary themes. Second, data were regrouped into preliminary themes for focused analysis which led to formulation of themes and subthemes. Third, hermeneutical principles were used as all data were interpreted from the viewpoint of each theme. Three themes were identified: Manoeuvring along the edge; Dyspnoea within the pattern; and Dyspnoea outside the pattern. They were encompassed by the main finding: Manoeuvring along the edge of breathlessness. The nurses attempted to navigate between implicit and explicit care approaches and to create a sphere for relieving or avoiding further worsening of dyspnoea. Depending on the identified pattern for a particular dyspnoeic episode, nurses attributed different significance to the dyspnoea. Interacting in dyspnoeic situations places nurses in a dilemma: an implicit approach risk, deriving from exclusion of patients and performing hesitantly; or an explicit negotiation risk, where patients are exhausted and removed from focusing and breathing. The dilemma weakens nurses' opportunities to relieve or avoid a worsening of the dyspnoea. Likewise, the divergence between nurses' and patients' assessment of dyspnoea as within or outside the pattern appears to jeopardize the efficiency of care. Our findings contribute to a deeper understanding of the challenges of respiratory nursing care in general, and the challenges of relieving in-patients' dyspnoea in particular.

  14. Efficacy of budesonide/formoterol maintenance and reliever therapy compared with higher-dose budesonide as step-up from low-dose inhaled corticosteroid treatment.

    PubMed

    Jenkins, Christine R; Eriksson, Göran; Bateman, Eric D; Reddel, Helen K; Sears, Malcolm R; Lindberg, Magnus; O'Byrne, Paul M

    2017-04-20

    Asthma management may involve a step up in treatment when symptoms are not well controlled. We examined whether budesonide/formoterol maintenance and reliever therapy (MRT) is as effective as higher, fixed-dose budesonide plus as-needed terbutaline in patients requiring step-up from Step 2 treatment (low-dose inhaled corticosteroids), stratified by baseline reliever use. A post-hoc analysis utilized data from three clinical trials of 6-12 months' duration. Patients aged ≥12 years with symptomatic asthma uncontrolled despite Step 2 treatment were included. Severe exacerbation rate, lung function and reliever use were analysed, stratified by baseline reliever use (<1, 1-2 and >2 occasions/day). Overall, 1239 patients were included. Reductions in severe exacerbation rate with budesonide/formoterol MRT versus fixed-dose budesonide were similar across baseline reliever use levels, and were statistically significant in patients using 1-2 (42%, p = 0.01) and >2 (39%, p = 0.02) reliever occasions/day, but not <1 reliever occasion/day (35%, p = 0.11). Both treatments significantly increased mean FEV 1 from baseline; improvements were significantly greater for budesonide/formoterol MRT in all reliever use groups. Reductions in reliever use from baseline were significantly greater with budesonide/formoterol MRT versus fixed-dose budesonide in patients using 1-2 and >2 reliever occasions/day (-0.33 and -0.74 occasions/day, respectively). Treatment benefit with budesonide/formoterol MRT versus higher, fixed-dose budesonide plus short-acting β 2 -agonist was found in Step 2 patients with relatively low reliever use, supporting the proposal that budesonide/formoterol MRT may be useful when asthma is uncontrolled with low-dose inhaled corticosteroid.

  15. Environmental Risks of Nano Zerovalent Iron for Arsenate Remediation: Impacts on Cytosolic Levels of Inorganic Phosphate and MgATP2- in Arabidopsis thaliana.

    PubMed

    Zhang, Weilan; Lo, Irene M C; Hu, Liming; Voon, Chia Pao; Lim, Boon Leong; Versaw, Wayne K

    2018-04-03

    The use of nano zerovalent iron (nZVI) for arsenate (As(V)) remediation has proven effective, but full-scale injection of nZVI into the subsurface has aroused serious concerns for associated environmental risks. This study evaluated the efficacy of nZVI treatment for arsenate remediation and its potential hazards to plants using Arabidopsis thaliana grown in a hydroponic system. Biosensors for inorganic phosphate (Pi) and MgATP 2- were used to monitor in vivo Pi and MgATP 2- levels in plant cells. The results showed that nZVI could remove As(V) from growth media, decrease As uptake by plants, and mitigate As(V) toxicity to plants. However, excess nZVI could cause Pi starvation in plants leading to detrimental effects on plant growth. Due to the competitive adsorption of As(V) and Pi on nZVI, removing As(V) via nZVI treatment at an upstream site could relieve downstream plants from As(V) toxicity and Pi deprivation, in which case 100 mg/L of nZVI was the optimal dosage for remediation of As(V) at a concentration around 16.13 mg/L.

  16. Effectiveness of Iron Ethylenediamine-N,N'-bis(hydroxyphenylacetic) Acid (o,o-EDDHA/Fe3+) Formulations with Different Ratios of Meso and d,l-Racemic Isomers as Iron Fertilizers.

    PubMed

    Alcañiz, Sara; Jordá, Juana D; Cerdán, Mar

    2017-01-18

    Two o,o-EDDHA/Fe 3+ formulations (meso, 93.5% w/w of meso isomer; and d,l-racemic, 91.3% w/w of d,l-racemic mixture) were prepared, and their efficacy to avoid or to relieve iron deficiency in Fe-sufficient and Fe-deficient tomato plants grown on hydroponic solution was compared with that of the current o,o-EDDHA/Fe 3+ formulations (50% of meso and d,l-racemic isomers). The effectiveness of the three o,o-EDDHA/Fe 3+ formulations was different depending on the iron nutritional status of plants. The three o,o-EDDHA/Fe 3+ formulations tested were effective in preventing iron chlorosis in healthy plants. However, the higher the meso concentration in the formulations, the higher the effectiveness in the recovery of iron chlorotic plants from iron deficiency. Accordingly, o,o-EDDHA/Fe 3+ formulations rich in meso isomer are recommended in hydroponic systems.

  17. Sales Training for Army Recruiter Success: Supplementary Information on Modeling the Sales Strategies and Skills of Excellent Recruiters

    DTIC Science & Technology

    1987-11-01

    feel your parachute deploying ... ? The recruiter will want to finish the experience he has created and taken the prospect through in a way that makes... finishing with a pleasant feeling or unspecified experience to relieve the tension: "You’re looking around ... your stomach was tighter than a knot...personal style. Even when the prospect has agreed to join the Army, the recruiter is not finished . He now has to prepare the prospect for processing at the

  18. Final Report Navajo Transmission Project (NTP)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bennie Hoisington; Steven Begay

    2006-09-14

    The Diné Power Authority is developing the Navajo Transmission Project (NTP) to relieve the constraints on the transmission of electricity west of the Four Corners area and to improve the operation flexibility and reliability of the extra-high-voltage transmission system in the region. The NTP creates the wholesale transmission capacity for more economical power transfers, sales, and purchases in the region. It will facilitate the development of Navajo energy resources, improve economic conditions on the Navajo Nation as well as allow DPA to participate in the western electrical utility industry.

  19. The Proposal and Early Results of Capitate Forage as a New Treatment Method for Kienböck's Disease.

    PubMed

    Bekler, Halil Ibrahim; Erdag, Yiğit; Gumustas, Seyit Ali; Pehlivanoglu, Gökhan

    2013-12-01

    Kienböck's disease is a type of avascular necrosis which disrupts the biomechanics of the wrist as a result of the changes it creates in the lunate bone. Its treatment generally consists of osteotomies intended to relieve the pressure on the bone, pedicle bone grafting applications aiming to increase bone blood supply, and salvage procedures. Capitate forage is a safe and simple-to-apply surgical treatment method which is intended to enhance neovascularization of the lunate much like a radius osteotomy or core decompression.

  20. Investigations of anti-inflammatory and antinociceptive activities of Piper cubeba, Physalis angulata and Rosa hybrida.

    PubMed

    Choi, Eun-Mi; Hwang, Jae-Kwan

    2003-11-01

    The anti-inflammatory activities of Piper cubeba (fruit), Physalis angulata (flower) and Rosa hybrida (flower) were determined by carrageenan-induced paw edema, arachidonic acid-induced ear edema and formaldehyde-induced arthritis in mice. The anti-allergic and analgesic activities of these plants were also studied by using 2,4-dinitrofluorobenzene (DNFB)-induced contact hypersensitivity reaction (type IV) and hot plate test in mice, respectively. These plant extracts clearly exhibited inhibitory effects against acute and subacute inflammation by oral administration (200 mg/kg). Also, administration (200 mg/kg, p.o.) of plant extracts for 1 week significantly inhibited type IV allergic reaction in mice (P<0.05). Rosa hybrida showed an analgesic effect against hot plate-induced thermal stimulation at a dose of 200 mg/kg. These results provide support for the use of Rosa hybrida in relieving inflammatory pain, and insight into the development of new agents for treating inflammatory diseases.

  1. Down-regulation of respiration in pear fruit depends on temperature.

    PubMed

    Ho, Quang Tri; Hertog, Maarten L A T M; Verboven, Pieter; Ambaw, Alemayehu; Rogge, Seppe; Verlinden, Bert E; Nicolaï, Bart M

    2018-04-09

    The respiration rate of plant tissues decreases when the amount of available O2 is reduced. There is, however, a debate on whether the respiration rate is controlled either by diffusion limitation of oxygen or through regulatory processes at the level of the transcriptome. We used experimental and modelling approaches to demonstrate that both diffusion limitation and metabolic regulation affect the response of respiration of bulky plant organs such as fruit to reduced O2 levels in the surrounding atmosphere. Diffusion limitation greatly affects fruit respiration at high temperature, but at low temperature respiration is reduced through a regulatory process, presumably a response to a signal generated by a plant oxygen sensor. The response of respiration to O2 is time dependent and is highly sensitive, particularly at low O2 levels in the surrounding atmosphere. Down-regulation of the respiration at low temperatures may save internal O2 and relieve hypoxic conditions in the fruit.

  2. 21 CFR 341.85 - Labeling of permitted combinations of active ingredients.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... “pain reliever” or “analgesic (pain reliever).” If the product is also labeled to relieve fever, then the analgesic-antipyretic component is identified as a “pain reliever-fever reducer” or “analgesic (pain reliever)-antipyretic (fever reducer).” (2) [Reserved] (b) Indications. The labeling of the...

  3. 21 CFR 341.85 - Labeling of permitted combinations of active ingredients.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... “pain reliever” or “analgesic (pain reliever).” If the product is also labeled to relieve fever, then the analgesic-antipyretic component is identified as a “pain reliever-fever reducer” or “analgesic (pain reliever)-antipyretic (fever reducer).” (2) [Reserved] (b) Indications. The labeling of the...

  4. 21 CFR 341.85 - Labeling of permitted combinations of active ingredients.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... “pain reliever” or “analgesic (pain reliever).” If the product is also labeled to relieve fever, then the analgesic-antipyretic component is identified as a “pain reliever-fever reducer” or “analgesic (pain reliever)-antipyretic (fever reducer).” (2) [Reserved] (b) Indications. The labeling of the...

  5. The effect of budesonide/formoterol maintenance and reliever therapy on the risk of severe asthma exacerbations following episodes of high reliever use: an exploratory analysis of two randomised, controlled studies with comparisons to standard therapy

    PubMed Central

    2012-01-01

    Background Divergent strategies have emerged for the management of severe asthma. One strategy utilises high and fixed doses of maintenance treatment, usually inhaled corticosteroid/long-acting β2-agonist (ICS/LABA), supplemented by a short-acting β2-agonist (SABA) as needed. Alternatively, budesonide/formoterol is used as both maintenance and reliever therapy. The latter is superior to fixed-dose treatment in reducing severe exacerbations while achieving similar or better asthma control in other regards. Exacerbations may be reduced by the use of budesonide/formoterol as reliever medication during periods of unstable asthma. We examined the risk of a severe exacerbation in the period after a single day with high reliever use. Methods Episodes of high reliever use were quantified and exacerbations occurring post-index day with these episodes were examined post hoc in two double-blind studies comparing the efficacy and safety of budesonide/formoterol maintenance and reliever therapy (Symbicort SMART™, Turbuhaler®) 160/4.5 μg twice daily plus as needed with similar or higher maintenance doses of ICS/LABA plus SABA or formoterol. Results Budesonide/formoterol maintenance and reliever therapy significantly reduced the risk of episodes of high reliever use (>6 inhalations/day) vs. all alternative ICS/LABA regimens. With conventional fixed-dose treatment the need for exacerbation treatment within 21 days ranged from 6.0–10.1% of days post-index for all regimens compared with 2.5–3.4% of days with budesonide/formoterol maintenance and reliever therapy. Conclusions Budesonide/formoterol maintenance and reliever therapy reduces the incidence of high reliever episodes and the exacerbation burden immediately following these episodes vs. alternative ICS/LABA plus SABA regimens at up to double the maintenance dose of ICS. Trial registration These studies do not have registration numbers as they were conducted before clinical trial registration was required PMID:22816878

  6. How Landscape Plants Modify the Environment.

    ERIC Educational Resources Information Center

    Blankenship, Sylvia; Wise, Kevin

    1993-01-01

    Presents three experiments that provide examples of how plants modify their surroundings and create microenvironments. Examples demonstrate (1) how types of ground cover influence water quality; (2) how plants can create a thermal microenvironment; and (3) how plants can serve as barriers to wind. (MDH)

  7. Plant-wide (BSM2) evaluation of reject water treatment with a SHARON-Anammox process.

    PubMed

    Volcke, E I P; Gernaey, K V; Vrecko, D; Jeppsson, U; van Loosdrecht, M C M; Vanrolleghem, P A

    2006-01-01

    In wastewater treatment plants (WWTPs) equipped with sludge digestion and dewatering systems, the reject water originating from these facilities contributes significantly to the nitrogen load of the activated sludge tanks, to which it is typically recycled. In this paper, the impact of reject water streams on the performance of a WWTP is assessed in a simulation study, using the Benchmark Simulation Model no. 2 (BSM2), that includes the processes describing sludge treatment and in this way allows for plant-wide evaluation. Comparison of performance of a WWTP without reject water with a WWTP where reject water is recycled to the primary clarifier, i.e. the BSM2 plant, shows that the ammonium load of the influent to the primary clarifier is 28% higher in the case of reject water recycling. This results in violation of the effluent total nitrogen limit. In order to relieve the main wastewater treatment plant, reject water treatment with a combined SHARON-Anammox process seems a promising option. The simulation results indicate that significant improvements of the effluent quality of the main wastewater treatment plant can be realized. An economic evaluation of the different scenarios is performed using an Operating Cost Index (OCI).

  8. Rebound Headaches

    MedlinePlus

    ... relievers. Common pain relievers such as aspirin and acetaminophen (Tylenol, others) may contribute to rebound headaches — especially ... OTC) pain relievers that combine caffeine, aspirin and acetaminophen (Excedrin, others) are common culprits. This group also ...

  9. Contact dermatitis to Vicks VapoRub.

    PubMed

    Noiles, Kristin; Pratt, Melanie

    2010-01-01

    Vicks VapoRub (VVR) is a commonly used inhalant ointment that helps relieve symptoms of upper respiratory tract infections. It contains several plant substances, including turpentine oil, eucalyptus oil, and cedar leaf oil, which can potentially irritate or sensitize the skin, as well as camphor, menthol, nutmeg oil, and thymol. Although many reports describe allergic contact dermatitis (ACD) to the various constituents in VVR ointment, there are no cases of VVR directly causing ACD. We present a case of a patient who developed an ACD secondary to application of her VVR.

  10. Inversion Therapy: Can It Relieve Back Pain?

    MedlinePlus

    Inversion therapy: Can it relieve back pain? Does inversion therapy relieve back pain? Is it safe? Answers from Edward R. Laskowski, M.D. Inversion therapy doesn't provide lasting relief from back ...

  11. Determining critical pre- and post-anthesis periods and physiological processes in Lycopersicon esculentum Mill. exposed to moderately elevated temperatures.

    PubMed

    Sato, Suguru; Peet, Mary M; Thomas, Judith F

    2002-05-01

    To determine the thermosensitive periods and physiological processes in tomato flowers exposed to moderately elevated temperatures, tomato plants (Lycopersicon esculentum Mill., cv. NC 8288) were grown at 28/22 degrees C or 32/26 degrees C day/night temperature regimes and then transferred to the opposite regime for 0-15 d before or 0-24 h after anthesis. For plants initially grown at 28/22 degrees C, moderate temperature stress before anthesis decreased the percentage of fruit set per plant, but did not clarify the thermosensitive period. The same level of stress did not significantly reduce fruit set when applied immediately after anthesis. For plants initially grown at 32/26 degrees C, fruit set was completely prevented unless a relief period of more than 5 d was provided before anthesis. The same level of stress relief for 3-24 h after anthesis also increased fruit set. Plants were most sensitive to 32/26 degrees C temperatures 7-15 d before anthesis. Microscopic investigation of anthers in plants grown continuously at high temperature indicated disruption of development in the pollen, endothecium, epidermis, and stomium. This disruption was reduced, but still observable in plants relieved from high temperature for 10 d before anthesis.

  12. Treatment Options for Malignant Mesothelioma

    MedlinePlus

    ... as palliative therapy to relieve symptoms and improve quality of life . Chemotherapy Chemotherapy is a cancer treatment that uses ... as palliative therapy to relieve symptoms and improve quality of life . Radiation therapy as palliative therapy to relieve symptoms ...

  13. Stages of Malignant Mesothelioma

    MedlinePlus

    ... as palliative therapy to relieve symptoms and improve quality of life . Chemotherapy Chemotherapy is a cancer treatment that uses ... as palliative therapy to relieve symptoms and improve quality of life . Radiation therapy as palliative therapy to relieve symptoms ...

  14. Treatment Option Overview (Malignant Mesothelioma)

    MedlinePlus

    ... as palliative therapy to relieve symptoms and improve quality of life . Chemotherapy Chemotherapy is a cancer treatment that uses ... as palliative therapy to relieve symptoms and improve quality of life . Radiation therapy as palliative therapy to relieve symptoms ...

  15. Contralateral radiculopathy after transforaminal lumbar interbody fusion in the treatment of lumbar degenerative diseases: A Case Series.

    PubMed

    Hu, Hong-Tao; Ren, Liang; Sun, Xian-Ze; Liu, Feng-Yu; Yu, Jin-He; Gu, Zhen-Fang

    2018-04-01

    Transforaminal lumbar interbody fusion (TLIF) is an effective treatment for patients with degenerative lumbar disc disorder. Contralateral radiculopathy, as a complication of TLIF, has been recognized in this institution, but is rarely reported in the literature. In this article, we report 2 cases of contralateral radiculopathy after TLIF in our institution and its associated complications. In the 2 cases, the postoperative computed tomography (CT) and magnetic resonance image (MRI) showed obvious upward movement of the superior articular process, leading to contralateral foraminal stenosis. Revision surgery was done at once to partially resect the opposite superior facet and to relieve nerve root compression. After revision surgery, the contralateral radiculopathy disappeared. Contralateral radiculopathy is an avoidable potential complication. It is very important to create careful preoperative plans and to conscientiously plan the use of intraoperative techniques. In case of postoperative contralateral leg pain, the patients should be examined by CT and MRI. If CT and MRI show that the superior articular process significantly migrated upwards, which leads to contralateral foraminal stenosis, revision surgery should be done at once to partially resect the contralateral superior facet so as to relieve nerve root compression and avoid possible long-term impairment.

  16. Physiological integration enhanced the tolerance of Cynodon dactylon to flooding.

    PubMed

    Li, Z J; Fan, D Y; Chen, F Q; Yuan, Q Y; Chow, W S; Xie, Z Q

    2015-03-01

    Many flooding-tolerant species are clonal plants; however, the effects of physiological integration on plant responses to flooding have received limited attention. We hypothesise that flooding can trigger changes in metabolism of carbohydrates and ROS (reactive oxygen species) in clonal plants, and that physiological integration can ameliorate the adverse effects of stress, subsequently restoring the growth of flooded ramets. In the present study, we conducted a factorial experiment combining flooding to apical ramets and stolon severing (preventing physiological integration) between apical and basal ramets of Cynodon dactylon, which is a stoloniferous perennial grass with considerable flooding tolerance. Flooding-induced responses including decreased root biomass, accumulation of soluble sugar and starch, as well as increased activity of superoxide dismutase (SOD) and ascorbate peroxidase (APX) in apical ramets. Physiological integration relieved growth inhibition, carbohydrate accumulation and induction of antioxidant enzyme activity in stressed ramets, as expected, without any observable cost in unstressed ramets. We speculate that relief of flooding stress in clonal plants may rely on oxidising power and electron acceptors transferred between ramets through physiological integration. © 2014 German Botanical Society and The Royal Botanical Society of the Netherlands.

  17. Traditional used Plants against Cognitive Decline and Alzheimer Disease

    PubMed Central

    Eckert, Gunter Peter

    2010-01-01

    Alzheimer's disease (AD) is a neurodegenerative disorder characterized clinically by progressive memory deficits, impaired cognitive function, and altered and inappropriate behavior. Aging represents the most important risk factor for AD and the global trend in the phenomenon of population aging has dramatic consequences for public health, healthcare financing, and delivery systems in the word and, especially in developing countries. Mounting evidence obtained in in vitro and in vivo studies, suggests that various traditionally used plants in Asia, India, and Europe significantly affect key metabolic alterations culminating in AD-typical neurodegeneration. The present article aims to bring the reader up-to-date on the most recent studies and advances describing the direct and indirect activities of traditional used plants and its constituents possibly relieving features of AD. A variety of traditional used plants and its extracts exerted activities on AD related drug targets including AChE activity, antioxidative activity, modulation of Aβ-producing secretase activities, Aβ-degradation, heavy metal chelating, induction of neurotrophic factors, and cell death mechanisms. Although pre-clinical investigations identified promising drug candidates for AD, clinical evidences are still pending. PMID:21833177

  18. Vulnerability of US thermoelectric power generation to climate change when incorporating state-level environmental regulations

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Liu, Lu; Hejazi, Mohamad; Li, Hongyi

    This study explores the interactions between climate and thermoelectric generation in the U.S. by coupling an Earth System Model with a thermoelectric power generation model. We validated model simulations of power production for selected power plants (~44% of existing thermoelectric capacity) against reported values. In addition, we projected future usable capacity for existing power plants under two different climate change scenarios. Results indicate that climate change alone may reduce average thermoelectric generating capacity by 2%-3% by the 2060s. Reductions up to 12% are expected if environmental requirements are enforced without waivers for thermal variation. This study concludes that the impactmore » of climate change on the U.S. thermoelectric power system is less than previous estimates due to an inclusion of a spatially-disaggregated representation of environmental regulations and provisional variances that temporarily relieve power plants from permit requirements. This work highlights the significance of accounting for legal constructs in which the operation of power plants are managed, and underscores the effects of provisional variances in addition to environmental requirements.« less

  19. Hand-held instrument should relieve hematoma pressure

    NASA Technical Reports Server (NTRS)

    Raggio, L. J.; Robertson, T. L.

    1967-01-01

    Portable instrument relieves hematomas beneath fingernails and toenails without surgery. This device simplifies the operative procedure with an instant variable heating tip, adjustable depth settings and interchangeable tip sizes for cauterizing small areas and relieving pressurized clots.

  20. Risks associated with managing asthma without a preventer: urgent healthcare, poor asthma control and over-the-counter reliever use in a cross-sectional population survey.

    PubMed

    Reddel, Helen K; Ampon, Rosario D; Sawyer, Susan M; Peters, Matthew J

    2017-09-25

    Overuse of asthma relievers, particularly without anti-inflammatory preventers, increases asthma risks. This study aimed to identify how many reliever-only users have urgent healthcare, explore their attitudes and beliefs about asthma and its treatment, and investigate whether purchasing over-the-counter relievers was associated with worse asthma outcomes than by prescription. Cross-sectional population-based Internet survey in Australia. Of 2686 participants ≥16 years with current asthma randomly drawn from a web-based panel, 1038 (50.7% male) used only reliever medication. Urgent asthma-related healthcare; Asthma Control Test (ACT); patient attitudes about asthma and medications; reliever purchase (with/without prescription). Of 1038 reliever-only participants, 23.3% had required urgent healthcare for asthma in the previous year, and only 36.0% had a non-urgent asthma review. Those needing urgent healthcare were more likely than those without such events to be male (56.5% vs 49.0%, p=0.003) and current smokers (29.4% vs 23.3%, p=0.009). Only 30.6% had well-controlled asthma (ACT ≥20) compared with 71.0% of those with no urgent healthcare (p<0.0001), and 20.8% used relievers regularly to prevent asthma symptoms (vs 5.5% of those without urgent healthcare). Those with urgent healthcare were more frustrated by their asthma and less happy with how they managed it, and they were less confident about their ability to manage worsening asthma, but just as likely as those without urgent healthcare to manage worsening asthma themselves rather than visit a doctor. Reliever-only users purchasing over-the-counter relievers were no more likely than those purchasing relievers by prescription to have uncontrolled asthma (35.9% vs 40.6%, p=0.23) but were less likely to have had a non-urgent asthma review. One-quarter of the reliever-only population had needed urgent asthma healthcare in the previous year, demonstrating the importance of identifying such patients. Their attitudes and beliefs suggest opportunities for targeting this population in the community. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  1. The power of environment.

    PubMed

    Westbury, Becky

    2015-06-01

    In Ten tips for normal birth, the Royal College of Midwives (RCM) (2014) advocates the building of nests; creating an environment that helps women to feel safe and secure during birth, as this can improve women's experiences and likelihood of normal birth. Furthermore, a private, undisturbed and dark environment, where women feel calm and safe can promote the release of oxytocin, the hormone responsible for uterine contractions and thought to promote the release of the pain relieving hormones endorphins (Uvnas Moberg 2003). When this is not achieved, women can experience fear-tension-pain syndrome, impeding labour progress and causing increased levels of pain (Dick-Read 2013). In addition, birth space has the potential to encourage the promotion of normality through providing space to mobilise, and alternative furniture to enable upright birth positions. Midwives should help women to create a birth space in which they feel safe, calm and secure, to promote normality and increase the incidence of normal birth (RCM 2014).

  2. A phytobeneficial strain Planomicrobium sp. MSSA-10 triggered oxidative stress responsive mechanisms and regulated the growth of pea plants under induced saline environment.

    PubMed

    Shahid, M; Akram, M S; Khan, M A; Zubair, M; Shah, S M; Ismail, M; Shabir, G; Basheer, S; Aslam, K; Tariq, M

    2018-06-01

    The study was planned to characterize Planomicrobium sp. MSSA-10 for plant-beneficial traits and to evaluate its inoculation impact on physiology of pea plants under different salinity levels. Strain MSSA-10 was isolated from pea rhizosphere and identified by the analysis of 16S rRNA gene sequence. The strain demonstrated phosphate solubilization and auxin production up to 2 mol l -1 NaCl and exhibited 1-aminocyclopropane-1-carboxylic acid deaminase activity up to 1·5 mol l -1 salt. In an inoculation experiment under different salinity regimes, a significant increase in growth was observed associated with decreased levels of reactive oxygen species and enhanced antioxidative enzyme activities. The strain also promoted the translocation of nutrients in plants with subsequent increase in chlorophyll and protein contents as compared to noninoculated plants. It has been observed that rifampicin-resistant derivatives of MSSA-10 were able to survive for 30 days at optimum cell density with pea rhizosphere. Growth-stimulating effect of MSSA-10 on pea plants may be attributed to its rhizosphere competence, nutrient mobilization and modulation of plant oxidative damage repair mechanisms under saline environment. Planomicrobium sp. MSSA-10 might be used as potent bioinoculant to relieve pea plants from deleterious effects of salinity. © 2018 The Society for Applied Microbiology.

  3. Entomopathogenic and plant pathogenic nematodes as opposing forces in agriculture.

    PubMed

    Kenney, Eric; Eleftherianos, Ioannis

    2016-01-01

    Plant-parasitic nematodes are responsible for substantial damages within the agriculture industry every year, which is a challenge that has thus far gone largely unimpeded. Chemical nematicides have been employed with varying degrees of success, but their implementation can be cumbersome, and furthermore they could potentially be neutralising an otherwise positive effect from the entomopathogenic nematodes that coexist with plant-parasitic nematodes in soil environments and provide protection for plants against insect pests. Recent research has explored the potential of employing entomopathogenic nematodes to protect plants from plant-parasitic nematodes, while providing their standard degree of protection against insects. The interactions involved are highly complex, due to both the three-organism system and the assortment of variables present in a soil environment, but a strong collection of evidence has accumulated regarding the suppressive capacity of certain entomopathogenic nematodes and their mutualistic bacteria, in the context of limiting the infectivity of plant-parasitic nematodes. Specific factors produced by certain entomopathogenic nematode complexes during the process of insect infection appear to have a selectively nematicidal, or at least repellant, effect on plant-parasitic nematodes. Using this information, an opportunity has formed to adapt this relationship to large-scale, field conditions and potentially relieve the agricultural industry of one of its most substantial burdens. Copyright © 2015 Australian Society for Parasitology Inc. Published by Elsevier Ltd. All rights reserved.

  4. Plant defences against ants provide a pathway to social parasitism in butterflies.

    PubMed

    Patricelli, Dario; Barbero, Francesca; Occhipinti, Andrea; Bertea, Cinzia M; Bonelli, Simona; Casacci, Luca P; Zebelo, Simon A; Crocoll, Christoph; Gershenzon, Jonathan; Maffei, Massimo E; Thomas, Jeremy A; Balletto, Emilio

    2015-07-22

    Understanding the chemical cues and gene expressions that mediate herbivore-host-plant and parasite-host interactions can elucidate the ecological costs and benefits accruing to different partners in tight-knit community modules, and may reveal unexpected complexities. We investigated the exploitation of sequential hosts by the phytophagous-predaceous butterfly Maculinea arion, whose larvae initially feed on Origanum vulgare flowerheads before switching to parasitize Myrmica ant colonies for their main period of growth. Gravid female butterflies were attracted to Origanum plants that emitted high levels of the monoterpenoid volatile carvacrol, a condition that occurred when ants disturbed their roots: we also found that Origanum expressed four genes involved in monoterpene formation when ants were present, accompanied by a significant induction of jasmonates. When exposed to carvacrol, Myrmica workers upregulated five genes whose products bind and detoxify this biocide, and their colonies were more tolerant of it than other common ant genera, consistent with an observed ability to occupy the competitor-free spaces surrounding Origanum. A cost is potential colony destruction by Ma. arion, which in turn may benefit infested Origanum plants by relieving their roots of further damage. Our results suggest a new pathway, whereby social parasites can detect successive resources by employing plant volatiles to simultaneously select their initial plant food and a suitable sequential host.

  5. Plant defences against ants provide a pathway to social parasitism in butterflies

    PubMed Central

    Patricelli, Dario; Barbero, Francesca; Occhipinti, Andrea; Bertea, Cinzia M.; Bonelli, Simona; Casacci, Luca P.; Zebelo, Simon A.; Crocoll, Christoph; Gershenzon, Jonathan; Maffei, Massimo E.; Thomas, Jeremy A.; Balletto, Emilio

    2015-01-01

    Understanding the chemical cues and gene expressions that mediate herbivore–host-plant and parasite–host interactions can elucidate the ecological costs and benefits accruing to different partners in tight-knit community modules, and may reveal unexpected complexities. We investigated the exploitation of sequential hosts by the phytophagous–predaceous butterfly Maculinea arion, whose larvae initially feed on Origanum vulgare flowerheads before switching to parasitize Myrmica ant colonies for their main period of growth. Gravid female butterflies were attracted to Origanum plants that emitted high levels of the monoterpenoid volatile carvacrol, a condition that occurred when ants disturbed their roots: we also found that Origanum expressed four genes involved in monoterpene formation when ants were present, accompanied by a significant induction of jasmonates. When exposed to carvacrol, Myrmica workers upregulated five genes whose products bind and detoxify this biocide, and their colonies were more tolerant of it than other common ant genera, consistent with an observed ability to occupy the competitor-free spaces surrounding Origanum. A cost is potential colony destruction by Ma. arion, which in turn may benefit infested Origanum plants by relieving their roots of further damage. Our results suggest a new pathway, whereby social parasites can detect successive resources by employing plant volatiles to simultaneously select their initial plant food and a suitable sequential host. PMID:26156773

  6. Phytonanotherapy for management of diabetes using green synthesis nanoparticles.

    PubMed

    Anand, K; Tiloke, C; Naidoo, Pragalathan; Chuturgoon, A A

    2017-08-01

    The world has a rich diversity of indigenous medicinal plants. The World Health Organization (WHO) gives high priority to eco-friendly, non-hazardous and cost effective healthcare such as the use of medicinal plants to treat various illnesses, including Human immunodeficiency virus (HIV) infection and Acquired immune deficiency syndrome (AIDS), tuberculosis (TB), diabetes mellitus (DM), malaria, and cancer. In developing countries, a high proportion of the population tends to use complementary and alternative medicines (CAM) together with conventional prescription drugs. Globally, CAM has been used in both developed and developing countries. In China, 30-50% of medicinal use is based on traditional alternative medicine. In Africa, it is estimated that 80% of primary health care is CAM, whilst in the USA, about 158 million people us CAM. This increase is due to three main influences: improve their eminence of life, relieve symptoms and preclude long-term complications. Despite the advances and advantages of conventional pharmaceutical medication, these are associated with long-term side effects and pose risks of inefficacy for treatment of chronic diseases such as cancer and DM. The biosynthesis of metal nanoparticles (NPs) using medicinal plants has received considerable attention as a proper alternative to using hazardous chemical and physical synthetic techniques. Plants are being exploited for their unique metal tolerance and effective production of gold metal NPs. A single medicinal plant contains an orchestra of chemical elements (e.g. proteins, vitamins, enzymes, amino acids, polysaccharides and organic compounds) that are "environmentally benign, yet chemically complex" and therefore serve as ideal tools for enhanced medicinal applications. It is reported that phytocompounds such as terpenoids, polysaccharides, polyols and flavones take part in the bio-reduction, stabilization and bio-capping mechanisms to form stable gold and silver NPs. Also the inhibitory potential of plant compounds against diabetic targets followed by a study of enzyme inhibitor kinetics, ligand binding dynamics supported by in silico docking studies that reveal the mode of bioactive compounds and their inhibitory activities. The present review focuses on the potential anticancer, antidiabetic and antimicrobial activity of phyto-synthesized gold and silver NPs. In phytonanotherapy, synergistic features of plant and metal NPs are unique as they offer healing properties that may be the clinical bioequivalent to many synthetic drugs, with minimal side effects. This could provide alternative treatment for chronic diseases that is efficient to overcome the disadvantages of synthetic monotherapy and allows medicinal plant therapy to co-exist with current synthetic treatments. This creates a much needed paradigm shift for further clinical studies in non-communicable and communicable diseases. Copyright © 2017 Elsevier B.V. All rights reserved.

  7. How Do Pain Relievers Work? (For Kids)

    MedlinePlus

    ... First Aid & Safety Doctors & Hospitals Videos Recipes for Kids Kids site Sitio para niños How the Body Works ... Español How Do Pain Relievers Work? KidsHealth / For Kids / How Do Pain Relievers Work? Print en español ¿ ...

  8. Evaluation of U.S. Commercial-Off-the-Shelf Hand-Held Assays to Detect Opiate Pain Reliever Compounds in Multiple Biofluids

    DTIC Science & Technology

    2016-09-01

    EVALUATION OF U.S. COMMERCIAL-OFF-THE-SHELF HAND-HELD ASSAYS TO DETECT OPIATE PAIN RELIEVER COMPOUNDS IN...Commercial-Off-the-Shelf Hand-Held Assays to Detect Opiate Pain Reliever Compounds in Multiple Biofluids 5a. CONTRACT NUMBER 5b. GRANT NUMBER R...study, we evaluated the potential for several U.S. commercial-off-the-shelf (COTS) hand-held assays (HHAs) to detect members of the opiate pain reliever

  9. Understanding Americans' views on opioid pain reliever abuse.

    PubMed

    Barry, Colleen L; Kennedy-Hendricks, Alene; Gollust, Sarah E; Niederdeppe, Jeff; Bachhuber, Marcus A; Webster, Daniel W; McGinty, Emma E

    2016-01-01

    Opioid pain reliever abuse rates have increased sharply in the United States. This study examines Americans' personal experience with opioid pain reliever use and abuse, and views about the seriousness of the problem, factors causing it, responsibility for addressing it and support for policies to resolve it. Public opinion survey. A nationally representative US adult sample (n = 1111). Experiences with opioid pain relievers and views about the seriousness, causes of and responsibility for addressing the problem, and support for policies to reduce opioid pain reliever abuse. 28.2 per cent of Americans reported using opioid pain relievers in the last 12 months, 69.5% have used them in their life-time and 17.3% reported using these medications when not prescribed to them. Fifty-eight per cent ranked the problem as serious, on a par with other major health concerns. Individual-orientated factors, including a lack of understanding about how easy it is to become addicted (80.0%) and improper storage (65.1%) and disposal (64.1%), ranked highest as causes, and those abusing opioid pain relievers (83.8%) and their physicians (78.0%) were viewed as most responsible for solving the problem. Of the policies recommended to curb the epidemic, 14 of 16 were supported by a majority of Americans. Americans view the problem of opioid pain reliever abuse as serious, and support nearly all the policies recommended by medical, law enforcement, disease control and public health experts to curb the epidemic. © 2015 Society for the Study of Addiction.

  10. St. John's Wort seed and feverfew flower extracts relieve painful diabetic neuropathy in a rat model of diabetes.

    PubMed

    Galeotti, Nicoletta; Maidecchi, Anna; Mattoli, Luisa; Burico, Michela; Ghelardini, Carla

    2014-01-01

    Painful diabetic peripheral neuropathy (DPN) is a common complication of diabetes and the few approved therapies for the management of pain have limited efficacy and side effects. With the aim to explore and develop new pharmacological treatments, we investigated the antihyperalgesic properties of St. John's Wort (SJW) and feverfew in streptozotocin (STZ)-diabetic rats. Acute administration of a SJW seed extract reversed mechanical hyperalgesia with a prolonged effect. A SJW extract obtained from the aerial portion of the plant and a feverfew flower extract partially relieved neuropathic pain whereas a feverfew leaf extract was ineffective. The antihyperalgesic efficacy of these herbal drugs was comparable to that of clinically used antihyperalgesic drugs (carbamazepine, lamotrigine, l-acetyl-levocarnitine). Further examinations of SJW and feverfew composition revealed that hyperforin and hypericin might be responsible for the antihyperalgesic properties of SJW whereas the efficacy of feverfew seems to be related to the presence of parthenolide. Rats undergoing treatment with SJW and feverfew did not show any behavioral side effect or sign of altered locomotor activity. Our results suggest that SJW and feverfew extracts may become new therapeutic perspectives for painful DPN. © 2013.

  11. Planting hope in loss and grief: self-care applications of horticultural therapy for grief caregivers in Taiwan.

    PubMed

    Lin, Yeh-Jen; Lin, Chi Yun; Li, Yu-Chan

    2014-01-01

    In 2008, the Taiwan Association for Care and Counseling for Loss organized a workshop about Horticultural Therapy, conducted as a participatory action research (PAR). Nineteen grief caregivers participated. Specific goals were designed according to a survey of participant expectations and focus-group discussions. The workshop content included lectures and interactive activities. Results demonstrated that most participants displayed an increased awareness of personal loss and meaning in grief, indicating that horticulture and nature appreciation might relieve individual grief and stress. The report introduces the rationale, evolution, execution, and results of the program development.

  12. Alpha-momorcharin enhances Tobacco mosaic virus resistance in tobaccoNN by manipulating jasmonic acid-salicylic acid crosstalk.

    PubMed

    Yang, Ting; Zhu, Li-Sha; Meng, Yao; Lv, Rui; Zhou, Zhuo; Zhu, Lin; Lin, Hong-Hui; Xi, De-Hui

    2018-04-01

    Alpha-momorcharin (α-MMC) is a type-I ribosome inactivating protein (RIP) with a molecular weight of 29 kDa found in plants. This protein has been shown to be effective against a broad range of human viruses and also has anti-tumor activities. However, the mechanism by which α-MMC induces plant defense responses and regulates the N gene to promote resistance to the Tobacco mosaic virus (TMV) is still not clear. By using pharmacological and infection experiments, we found that α-MMC enhances TMV resistance of tobacco plants containing the N gene (tobacco NN ). Our results showed that plants pretreated with 0.5 mg/ml α-MMC could relieve TMV-induced oxidative damage, had enhanced the expression of the N gene and increased biosynthesis of jasmonic acid (JA) and salicylic acid (SA). Moreover, transcription of JA and SA signaling pathway genes were increased, and their expression persisted for a longer period of time in plants pretreated with α-MMC compared with those pretreated with water. Importantly, exogenous application of 1-Aminobenzotriazole (ABT, SA inhibitor) and ibuprofen (JA inhibitor) reduced α-MMC induced plant resistance under viral infection. Thus, our results revealed that α-MMC enhances TMV resistance of tobacco NN plants by manipulating JA-SA crosstalk. Copyright © 2017 Elsevier GmbH. All rights reserved.

  13. 46 CFR 58.20-10 - Pressure relieving devices.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 2 2014-10-01 2014-10-01 false Pressure relieving devices. 58.20-10 Section 58.20-10 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING MAIN AND AUXILIARY MACHINERY AND RELATED SYSTEMS Refrigeration Machinery § 58.20-10 Pressure relieving devices. (a) Each...

  14. 46 CFR 58.20-10 - Pressure relieving devices.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 2 2013-10-01 2013-10-01 false Pressure relieving devices. 58.20-10 Section 58.20-10 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING MAIN AND AUXILIARY MACHINERY AND RELATED SYSTEMS Refrigeration Machinery § 58.20-10 Pressure relieving devices. (a) Each...

  15. 46 CFR 58.20-10 - Pressure relieving devices.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 2 2010-10-01 2010-10-01 false Pressure relieving devices. 58.20-10 Section 58.20-10 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING MAIN AND AUXILIARY MACHINERY AND RELATED SYSTEMS Refrigeration Machinery § 58.20-10 Pressure relieving devices. (a) Each...

  16. 46 CFR 58.20-10 - Pressure relieving devices.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 2 2011-10-01 2011-10-01 false Pressure relieving devices. 58.20-10 Section 58.20-10 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING MAIN AND AUXILIARY MACHINERY AND RELATED SYSTEMS Refrigeration Machinery § 58.20-10 Pressure relieving devices. (a) Each...

  17. 46 CFR 58.20-10 - Pressure relieving devices.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 2 2012-10-01 2012-10-01 false Pressure relieving devices. 58.20-10 Section 58.20-10 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING MAIN AND AUXILIARY MACHINERY AND RELATED SYSTEMS Refrigeration Machinery § 58.20-10 Pressure relieving devices. (a) Each...

  18. 49 CFR 192.201 - Required capacity of pressure relieving and limiting stations.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Design of Pipeline Components § 192.201 Required capacity of pressure relieving and limiting stations. (a) Each pressure relief station or pressure limiting station or group of those stations installed to... 49 Transportation 3 2012-10-01 2012-10-01 false Required capacity of pressure relieving and...

  19. 49 CFR 192.201 - Required capacity of pressure relieving and limiting stations.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Design of Pipeline Components § 192.201 Required capacity of pressure relieving and limiting stations. (a) Each pressure relief station or pressure limiting station or group of those stations installed to... 49 Transportation 3 2011-10-01 2011-10-01 false Required capacity of pressure relieving and...

  20. 49 CFR 192.201 - Required capacity of pressure relieving and limiting stations.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Design of Pipeline Components § 192.201 Required capacity of pressure relieving and limiting stations. (a) Each pressure relief station or pressure limiting station or group of those stations installed to... 49 Transportation 3 2013-10-01 2013-10-01 false Required capacity of pressure relieving and...

  1. 49 CFR 192.201 - Required capacity of pressure relieving and limiting stations.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Design of Pipeline Components § 192.201 Required capacity of pressure relieving and limiting stations. (a) Each pressure relief station or pressure limiting station or group of those stations installed to... 49 Transportation 3 2014-10-01 2014-10-01 false Required capacity of pressure relieving and...

  2. Medical marijuana for HIV-associated sensory neuropathy: legal and ethical issues.

    PubMed

    Larriviere, Daniel G

    2014-10-01

    The number of states legalizing medical marijuana is increasing. Medical marijuana is possibly effective therapy for HIV-associated sensory neuropathy. Despite legalization at the state level, however, the current and contradictory federal drug enforcement policy creates the risk that physicians who recommend medical marijuana to their patients will lose their ability to prescribe medications. The federal-state tension has legal and ethical implications for neurologists who receive a request for medical marijuana from their patients since neurologists must strive to both relieve suffering and obey relevant laws. Recommendation of medical marijuana by neurologists to their patients is ethically permissible but is not ethically mandatory.

  3. Predicting plant biomass accumulation from image-derived parameters

    PubMed Central

    Chen, Dijun; Shi, Rongli; Pape, Jean-Michel; Neumann, Kerstin; Graner, Andreas; Chen, Ming; Klukas, Christian

    2018-01-01

    Abstract Background Image-based high-throughput phenotyping technologies have been rapidly developed in plant science recently, and they provide a great potential to gain more valuable information than traditionally destructive methods. Predicting plant biomass is regarded as a key purpose for plant breeders and ecologists. However, it is a great challenge to find a predictive biomass model across experiments. Results In the present study, we constructed 4 predictive models to examine the quantitative relationship between image-based features and plant biomass accumulation. Our methodology has been applied to 3 consecutive barley (Hordeum vulgare) experiments with control and stress treatments. The results proved that plant biomass can be accurately predicted from image-based parameters using a random forest model. The high prediction accuracy based on this model will contribute to relieving the phenotyping bottleneck in biomass measurement in breeding applications. The prediction performance is still relatively high across experiments under similar conditions. The relative contribution of individual features for predicting biomass was further quantified, revealing new insights into the phenotypic determinants of the plant biomass outcome. Furthermore, methods could also be used to determine the most important image-based features related to plant biomass accumulation, which would be promising for subsequent genetic mapping to uncover the genetic basis of biomass. Conclusions We have developed quantitative models to accurately predict plant biomass accumulation from image data. We anticipate that the analysis results will be useful to advance our views of the phenotypic determinants of plant biomass outcome, and the statistical methods can be broadly used for other plant species. PMID:29346559

  4. Hyperactive mutant of a wheat plasma membrane Na+/H+ antiporter improves the growth and salt tolerance of transgenic tobacco.

    PubMed

    Zhou, Yang; Lai, Zesen; Yin, Xiaochang; Yu, Shan; Xu, Yuanyuan; Wang, Xiaoxiao; Cong, Xinli; Luo, Yuehua; Xu, Haixia; Jiang, Xingyu

    2016-12-01

    Wheat SOS1 (TaSOS1) activity could be relieved upon deletion of the C-terminal 168 residues (the auto-inhibitory domain). This truncated form of wheat SOS1 (TaSOS1-974) was shown to increase compensation (compared to wild-type TaSOS1) for the salt sensitivity of a yeast mutant strain, AXT3K, via increased Na + transportation out of cells during salinity stress. Expression of the plasma membrane proteins TaSOS1-974 or TaSOS1 improved the growth of transgenic tobacco plants compared with wild-type plants under normal conditions. However, plants expressing TaSOS1-974 grew better than TaSOS1-transformed plants. Upon salinity stress, Na + efflux and K + influx rates in the roots of transgenic plants expressing TaSOS1-974 or TaSOS1 were greater than those of wild-type plants. Furthermore, compared to TaSOS1-transgenic plants, TaSOS1-974-expressing roots showed faster Na + efflux and K + influx, resulting in less Na + and more K + accumulation in TaSOS1-974-transgenic plants compared to TaSOS1-transgenic and wild-type plants. TaSOS1-974-expressing plants had the lowest MDA content and electrolyte leakage among all tested plants, indicating that TaSOS1-974 might protect the plasma membrane against oxidative damage generated by salt stress. Overall, TaSOS1-974 conferred higher salt tolerance in transgenic plants compared to TaSOS1. Consistent with this result, transgenic plants expressing TaSOS1-974 showed a better growth performance than TaSOS1-expressing and wild-type plants under saline conditions. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  5. Electrical Signals in Prayer Plants (Marantaceae)? Insights into the Trigger Mechanism of the Explosive Style Movement

    PubMed Central

    Jerominek, Markus; Claßen-Bockhoff, Regine

    2015-01-01

    The explosive pollination mechanism of the prayer plants (Marantaceae) is unique among plants. After a tactile stimulus by a pollinator, the style curls up rapidly and mediates pollen exchange. It is still under discussion whether this explosive movement is released electrophysiologically, i.e. by a change in the membrane potential (as in Venus flytrap), or purely mechanically. In the present study, electrophysiological experiments are conducted to clarify the mechanism. Artificial release experiments (chemical and electrical) and electrophysiological measurements were conducted with two phylogenetically distant species, Goeppertia bachemiana (E. Morren) Borchs. & S. Suárez and Donax canniformis (G. Forst.) K. Schum. Electric responses recorded after style release by extracellular measurements are characterised as variation potentials due to their long repolarization phase and lack of self-perpetuation. In both species, chemical and electric stimulations do not release the style movement. It is concluded that the style movement in Marantaceae is released mechanically by relieving the tissue pressure. Accordingly, the variation potential is an effect of the movement and not its cause. The study exemplarily shows that fast movements in plants are not necessarily initiated by electric changes of the membrane as known from the Venus flytrap. PMID:25997015

  6. Electrical signals in prayer plants (marantaceae)? Insights into the trigger mechanism of the explosive style movement.

    PubMed

    Jerominek, Markus; Claßen-Bockhoff, Regine

    2015-01-01

    The explosive pollination mechanism of the prayer plants (Marantaceae) is unique among plants. After a tactile stimulus by a pollinator, the style curls up rapidly and mediates pollen exchange. It is still under discussion whether this explosive movement is released electrophysiologically, i.e. by a change in the membrane potential (as in Venus flytrap), or purely mechanically. In the present study, electrophysiological experiments are conducted to clarify the mechanism. Artificial release experiments (chemical and electrical) and electrophysiological measurements were conducted with two phylogenetically distant species, Goeppertia bachemiana (E. Morren) Borchs. & S. Suárez and Donax canniformis (G. Forst.) K. Schum. Electric responses recorded after style release by extracellular measurements are characterised as variation potentials due to their long repolarization phase and lack of self-perpetuation. In both species, chemical and electric stimulations do not release the style movement. It is concluded that the style movement in Marantaceae is released mechanically by relieving the tissue pressure. Accordingly, the variation potential is an effect of the movement and not its cause. The study exemplarily shows that fast movements in plants are not necessarily initiated by electric changes of the membrane as known from the Venus flytrap.

  7. Specific Activation of the Plant P-type Plasma Membrane H+-ATPase by Lysophospholipids Depends on the Autoinhibitory N- and C-terminal Domains.

    PubMed

    Wielandt, Alex Green; Pedersen, Jesper Torbøl; Falhof, Janus; Kemmer, Gerdi Christine; Lund, Anette; Ekberg, Kira; Fuglsang, Anja Thoe; Pomorski, Thomas Günther; Buch-Pedersen, Morten Jeppe; Palmgren, Michael

    2015-06-26

    Eukaryotic P-type plasma membrane H(+)-ATPases are primary active transport systems that are regulated at the post-translation level by cis-acting autoinhibitory domains, which can be relieved by protein kinase-mediated phosphorylation or binding of specific lipid species. Here we show that lysophospholipids specifically activate a plant plasma membrane H(+)-ATPase (Arabidopsis thaliana AHA2) by a mechanism that involves both cytoplasmic terminal domains of AHA2, whereas they have no effect on the fungal counterpart (Saccharomyces cerevisiae Pma1p). The activation was dependent on the glycerol backbone of the lysophospholipid and increased with acyl chain length, whereas the headgroup had little effect on activation. Activation of the plant pump by lysophospholipids did not involve the penultimate residue, Thr-947, which is known to be phosphorylated as part of a binding site for activating 14-3-3 protein, but was critically dependent on a single autoinhibitory residue (Leu-919) upstream of the C-terminal cytoplasmic domain in AHA2. A corresponding residue is absent in the fungal counterpart. These data indicate that plant plasma membrane H(+)-ATPases evolved as specific receptors for lysophospholipids and support the hypothesis that lysophospholipids are important plant signaling molecules. © 2015 by The American Society for Biochemistry and Molecular Biology, Inc.

  8. Changes in Photosynthetic Pigments, Total Phenolic Content, and Antioxidant Activity of Salvia coccinea Buc'hoz Ex Etl. Induced by Exogenous Salicylic Acid and Soil Salinity.

    PubMed

    Grzeszczuk, Monika; Salachna, Piotr; Meller, Edward

    2018-05-29

    Salvia coccinea (Lamiaceae) is a promising source of potential antioxidants, and its extracts can be used in pharmaceutical industry, as well as in food products and cosmetics. Salicylic acid (SA) affects many physiological and metabolic processes in vascular plants under salinity stress. The aim of this study was to investigate the response of S. coccinea to either SA, or sodium chloride (NaCl), or a combination of both. The plants were sprayed with a solution of 0.5 or 1.0 mM SA and watered with 0, 100, 200, or 300 mM NaCl. Exogenous application of SA increased the number of branches, fresh herbal weight, and total chlorophyll content vs control plants. Salinity-exposed plants showed reduced growth, content of photosynthetic pigments total polyphenols, and antioxidant activity. However, foliar application of SA relieved the adverse effects of 100 mM NaCl, as demonstrated by increased number of branches, greater fresh herbal weight, higher content of total chlorophyll, total carotenoids, and total polyphenols, as well as antioxidant potential, detected using ferric-reducing ability of plasma (FRAP) and 2.2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt (ABTS), compared with untreated plants.

  9. The potential of genetically enhanced plants to address food insecurity.

    PubMed

    Christou, Paul; Twyman, Richard M

    2004-06-01

    Food insecurity is one of the most important social issues faced today, with 840 million individuals enduring chronic hunger and three billion individuals suffering from nutrient deficiencies. Most of these individuals are poverty stricken and live in developing countries. Strategies to address food insecurity must aim to increase agricultural productivity in the developing world in order to tackle poverty, and must provide long-term improvements in crop yields to keep up with demand as the world's population grows. Genetically enhanced plants provide one route to sustainable higher yields, either by increasing the intrinsic yield capability of crop plants or by protecting them from biotic and abiotic constraints. The present paper discusses a range of transgenic approaches that could increase agricultural productivity if applied on a large scale, including the introduction of genes that confer resistance to pests and diseases, or tolerance of harsh environments, and genes that help to lift the intrinsic yield capacity by increasing metabolic flux towards storage carbohydrates, proteins and oils. The paper also explores how the nutritional value of plants can be improved by genetic engineering. Transgenic plants, as a component of integrated strategies to relieve poverty and deliver sustainable agriculture to subsistence farmers in developing countries, could have a significant impact on food security now and in the future.

  10. Use of Phenylboronic Acids to Investigate Boron Function in Plants. Possible Role of Boron in Transvacuolar Cytoplasmic Strands and Cell-to-Wall Adhesion

    PubMed Central

    Bassil, Elias; Hu, Hening; Brown, Patrick H.

    2004-01-01

    The only defined physiological role of boron in plants is as a cross-linking molecule involving reversible covalent bonds with cis-diols on either side of borate. Boronic acids, which form the same reversible bonds with cis-diols but cannot cross-link two molecules, were used to selectively disrupt boron function in plants. In cultured tobacco (Nicotiana tabacum cv BY-2) cells, addition of boronic acids caused the disruption of cytoplasmic strands and cell-to-cell wall detachment. The effect of the boronic acids could be relieved by the addition of boron-complexing sugars and was proportional to the boronic acid-binding strength of the sugar. Experiments with germinating petunia (Petunia hybrida) pollen and boronate-affinity chromatography showed that boronic acids and boron compete for the same binding sites. The boronic acids appear to specifically disrupt or prevent borate-dependent cross-links important for the structural integrity of the cell, including the organization of transvacuolar cytoplasmic strands. Boron likely plays a structural role in the plant cytoskeleton. We conclude that boronic acids can be used to rapidly and reversibly induce boron deficiency-like responses and therefore are useful tools for investigating boron function in plants. PMID:15466241

  11. Callose deposition during gravitropism of Zea mays and Pisum sativum and its inhibition by 2-deoxy-D-glucose

    NASA Technical Reports Server (NTRS)

    Jaffe, M. J.; Leopold, A. C.

    1984-01-01

    In etiolated corn (Zea mays L.) and etiolated pea (Pisum sativum L.) seedlings, a gravitropic stimulation induces the deposition of callose. In the corn coleoptiles this occurs within 5 min of gravity stimulation, and prior to the beginning of curvature. Both gravitropic curvature and callose deposition reach their maxima by 12 h. Within the first 2 h more callose is deposited on the upper (concave) side, but after 2-3 h, this deposition pattern is reversed. An inhibitor of protein glycosylation, 2-deoxy-D-glucose (DDG), inhibits callose production and considerably retards gravitropic bending in both species of plants. Mannose can relieve the inhibition of gravitropic bending by DDG. The pea mutant "Ageotropum", which does not respond to gravity when etiolated, also fails to produce callose in response to a gravitic stimulus. These correlations indicate that callose deposition may be a biochemical component of gravitropism in plant shoots.

  12. Esophageal dissection and hematoma associated with obstruction in an Indian elephant (Elephas maximus indicus).

    PubMed

    Phair, Kristen A; Sutherland-Smith, Meg; Pye, Geoffrey W; Pessier, Allan P; Clippinger, Tracy L

    2014-06-01

    A 42-year-old female Indian elephant (Elephas maximus indicus) developed a sudden onset of excessive salivation and dysphagia. Esophageal obstruction was suspected; possibly related to palm frond ingestion. Esophageal endoscopy revealed a mat of plant material in the distal esophagus. An initial attempt at relieving the obstruction was unsuccessful, but subsequent use of custom-made instruments along with insufflation and hydropulsion enabled partial removal of the material. Postimmobilization care included aggressive intravenous and rectal fluids, anti-inflammatory and antibiotic administration, and fasting. Despite treatment, the dysphagia persisted and the elephant was euthanized due to lack of improvement and grave prognosis. Postmortem examination revealed remaining plant material in the esophagus, complicated by an esophageal dissection, mural hematoma, and secondary bacterial infection. Iatrogenic trauma may have contributed to the extent of esophageal injury. Although treatment was ultimately unsuccessful, the supportive care employed could potentially aid recovery in cases of less severe esophageal trauma.

  13. Third international congress of plant molecular biology: Molecular biology of plant growth and development

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hallick, R.B.

    The Congress was held October 6-11, 1991 in Tucson with approximately 3000 scientists attending and over 300 oral presentations and 1800 posters. Plant molecular biology is one of the most rapidly developing areas of the biological sciences. Recent advances in the ability to isolate genes, to study their expression, and to create transgenic plants have had a major impact on our understanding of the many fundamental plant processes. In addition, new approaches have been created to improve plants for agricultural purposes. This is a book of presentation and posters from the conference.

  14. 31 CFR 585.521 - Donations of food to relieve human suffering authorized.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Donations of food to relieve human... Donations of food to relieve human suffering authorized. (a) Specific licenses may be issued on a case-by.... (b) In general, specific licenses will only be granted for donations of food to be provided through...

  15. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Atwater, Harry A.; Leite, Marina S.; Warmann, Emily C.

    A virtual substrate includes a handle support and a strain-relieved single crystalline layer on the handle support. A method of making the virtual substrate includes growing a coherently-strained single crystalline layer on an initial growth substrate, removing the initial growth substrate to relieve the strain on the single crystalline layer, and applying the strain-relieved single crystalline layer on a handle support.

  16. Stress corrosion evaluation of HP 9Ni-4Co-0.30C steel plate welds

    NASA Technical Reports Server (NTRS)

    Torres, Pablo D.

    1993-01-01

    A stress corrosion cracking (SCC) investigation was conducted on HP 9Ni-4Co-0.30C steel plate welds (welded by using straight polarity plasma arc and HP 9Ni-4Co-0.20C weld wire) since this material is being considered for use in the Advanced Solid Rocket Motor (ASRM) program. Prior to the welding, the material was double tempered at 538 C (1,000 F). After welding, only part of the material was stress relieved at 510 C (950 F) for 3 h. Round tensile specimens obtained from nonstress-relieved material were tested in 100-percent relative humidity at 38 C (100 F), in 3.5-percent NaCl alternate immersion, and in 5-percent salt spray at 35 C (95 F). Specimens obtained from stress-relieved material were tested in alternate immersion. The stress levels were 50, 75, and 90 percent of the corresponding 0.2-percent yield strength (YS). All the nonstress-relieved specimens exposed to salt spray and alternate immersion failed. Stress-relieved specimens (exposed to alternate immersion) failed at 75 and 90 percent of YS. No failures occurred at 50 percent of YS in the stress-relieved specimens which indicates a beneficial effect of the stress relief on the SCC resistance of these welds. The stress relief also had a positive effect on the mechanical properties of the welds (the most important being an increase of 21 percent on the YS). Under the conditions of these tests, the straight polarity plasma are welded HP 9Ni4Co-0.30C steel plate was found highly susceptible to SCC in the nonstress-relieved condition. This susceptibility to SCC was reduced by stress relieving.

  17. Nitrogen and dry-matter partitioning in soybean plants during onset of and recovery from nitrogen stress

    NASA Technical Reports Server (NTRS)

    Tolley-Henry, L.; Raper, C. D. Jr; Raper CD, J. r. (Principal Investigator)

    1986-01-01

    The study tested the hypothesis that resupplying nitrogen after a period of nitrogen stress leads to restoration of the balance between root and shoot growth and normal functional activity. Nonnodulated soybean plants were grown hydroponically for 14 days with 1.0 mM NO3- in a complete nutrient solution. One set of plants was continued on the complete nutrient solution for 25 days; a second set was given 0.0 mM NO3- for 25 days; and the third set was given 0.0 mM NO3- for 10 days followed by transfer to the complete solution with 1.0 mM NO3- for 15 days. In continuously nitrogen-stressed plants, emergence and expansion of main-stem and branch leaves were severely inhibited as low nitrogen content limited further growth. This was followed by a shift in partitioning of dry matter from the leaves to the roots, resulting in an initial stimulation of root growth and a decreased shoot:root ratio. Reduced nitrogen also was redistributed from the leaves into the stem and roots. When nitrogen stress was relieved, leaf initiation and expansion were renewed. With the restoration of the balance between root and shoot function, the shoot:root ratio and distribution of reduced nitrogen within the plant organs returned to levels similar to those of nonstressed plants.

  18. Reviewing the Literature on the Effectiveness of Pressure Relieving Movements

    PubMed Central

    Stinson, May

    2013-01-01

    Sitting for prolonged periods of time increases seating interface pressures, which is known to increase the risk of developing pressure ulcers. Those at risk of developing pressure ulcers are advised to perform pressure relieving movements such as “pushups” or “forward leans” in order to reduce the duration and magnitude of pressure acting on the vulnerable ischial tuberosity region. The aim of this review was to synthesize and critique the existing literature investigating the effectiveness of pressure relieving movements on seating interface pressures. The twenty-seven articles included in this paper highlight the need for further research investigating the effect of recommended pressure relieving movements on the pressures around the ischial tuberosities. Furthermore, this review found that the majority of individuals at risk of developing pressure ulcers do not adhere with the pressure relieving frequency or magnitude of movements currently recommended, indicating a need for pressure ulcer prevention to be explored further. PMID:23365733

  19. Plant-fungus competition for nitrogen erases mycorrhizal growth benefits of Andropogon gerardii under limited nitrogen supply.

    PubMed

    Püschel, David; Janoušková, Martina; Hujslová, Martina; Slavíková, Renata; Gryndlerová, Hana; Jansa, Jan

    2016-07-01

    Considered to play an important role in plant mineral nutrition, arbuscular mycorrhizal (AM) symbiosis is a common relationship between the roots of a great majority of plant species and glomeromycotan fungi. Its effects on the plant host are highly context dependent, with the greatest benefits often observed in phosphorus (P)-limited environments. Mycorrhizal contribution to plant nitrogen (N) nutrition is probably less important under most conditions. Moreover, inasmuch as both plant and fungi require substantial quantities of N for their growth, competition for N could potentially reduce net mycorrhizal benefits to the plant under conditions of limited N supply. Further compounded by increased belowground carbon (C) drain, the mycorrhizal costs could outweigh the benefits under severe N limitation. Using a field AM fungal community or a laboratory culture of Rhizophagus irregularis as mycorrhizal inoculants, we tested the contribution of mycorrhizal symbiosis to the growth, C allocation, and mineral nutrition of Andropogon gerardii growing in a nutrient-poor substrate under variable N and P supplies. The plants unambiguously competed with the fungi for N when its supply was low, resulting in no or negative mycorrhizal growth and N-uptake responses under such conditions. The field AM fungal communities manifested their potential to improve plant P nutrition only upon N fertilization, whereas the R. irregularis slightly yet significantly increased P uptake of its plant host (but not the host's growth) even without N supply. Coincident with increasing levels of root colonization by the AM fungal structures, both inoculants invariably increased nutritional and growth benefits to the host with increasing N supply. This, in turn, resulted in relieving plant P deficiency, which was persistent in non-mycorrhizal plants across the entire range of nutrient supplies.

  20. Faster photosynthetic induction in tobacco by expressing cyanobacterial flavodiiron proteins in chloroplasts.

    PubMed

    Gómez, Rodrigo; Carrillo, Néstor; Morelli, María P; Tula, Suresh; Shahinnia, Fahimeh; Hajirezaei, Mohammad-Reza; Lodeyro, Anabella F

    2018-05-01

    Plants grown in the field experience sharp changes in irradiation due to shading effects caused by clouds, other leaves, etc. The excess of absorbed light energy is dissipated by a number of mechanisms including cyclic electron transport, photorespiration, and Mehler-type reactions. This protection is essential for survival but decreases photosynthetic efficiency. All phototrophs except angiosperms harbor flavodiiron proteins (Flvs) which relieve the excess of excitation energy on the photosynthetic electron transport chain by reducing oxygen directly to water. Introduction of cyanobacterial Flv1/Flv3 in tobacco chloroplasts resulted in transgenic plants that showed similar photosynthetic performance under steady-state illumination, but displayed faster recovery of various photosynthetic parameters, including electron transport and non-photochemical quenching during dark-light transitions. They also kept the electron transport chain in a more oxidized state and enhanced the proton motive force of dark-adapted leaves. The results indicate that, by acting as electron sinks during light transitions, Flvs contribute to increase photosynthesis protection and efficiency under changing environmental conditions as those found by plants in the field.

  1. Biochar increases plant growth and alters microbial communities via regulating the moisture and temperature of green roof substrates.

    PubMed

    Chen, Haoming; Ma, Jinyi; Wei, Jiaxing; Gong, Xin; Yu, Xichen; Guo, Hui; Zhao, Yanwen

    2018-09-01

    Green roofs have increasingly been designed and applied to relieve environmental problems, such as water loss, air pollution as well as heat island effect. Substrate and vegetation are important components of green roofs providing ecosystem services and benefiting the urban development. Biochar made from sewage sludge could be potentially used as the substrate amendment for green roofs, however, the effects of biochar on substrate quality and plant performance in green roofs are still unclear. We evaluated the effects of adding sludge biochar (0, 5, 10, 15 and 20%, v/v) to natural soil planted with three types of plant species (ryegrass, Sedum lineare and cucumber) on soil properties, plant growth and microbial communities in both green roof and ground ecosystems. Our results showed that sludge biochar addition significantly increased substrate moisture, adjusted substrate temperature, altered microbial community structure and increased plant growth. The application rate of 10-15% sludge biochar on the green roof exerted the most significant effects on both microbial and plant biomass by 63.9-89.6% and 54.0-54.2% respectively. Path analysis showed that biochar addition had a strong effect on microbial biomass via changing the soil air-filled porosity, soil moisture and temperature, and promoted plant growth through the positive effects on microbial biomass. These results suggest that the applications of biochar at an appropriate rate can significantly alter plant growth and microbial community structure, and increase the ecological benefits of green roofs via exerting effects on the moisture, temperature and nutrients of roof substrates. Copyright © 2018 Elsevier B.V. All rights reserved.

  2. Planting Trees in Designed and Built Community Landscapes - Checklists for Success

    Treesearch

    Mary K. Reynolds; H. Sharon Ossenbruggen

    Trees create green spaces in communities. The right trees in the right places benefit you, your home, and your community now and in the future. It is essential to select living trees to create a sense of place within communities. This publication helps citizens create community green spaces. It encourages both experts and amateurs to plant and grow trees correctly, and...

  3. [Development characteristics of aquatic plants in a constructed wetland for treating urban drinking water source at its initial operation stage].

    PubMed

    Zheng, Jun; Ma, Xin-Tang; Zhou, Lan; Zhou, Qing-Yuan; Wang, Zhong-Qiong; Wang, Wei-Dong; Yin, Cheng-Qing

    2011-08-01

    The development characteristics and improvement measures of aquatic plants were studied in Shijiuyang Constructed Wetland (SCW) at its initial operation stage. SCW was a large-scale wetland aiming to help relieve the source water pollution in Jiaxing City. A checklist of vascular plants in SCW was built, and species composition, life forms, biomass and association distributions were examined. Our objectives were to examine the diversity and community structure of aquatic plants in SCW at its initial operation stage, and to find out the possible hydrophyte improvement measures. The survey results showed that there were 49 vascular plant species belonging to 41 genera, 25 families in SCW, which greatly exceeded the artificially transplanted 13 species. The life forms of present aquatic plants in SCW were dominated by hygrophilous plants (20 species) and emerged plants (17 species), which accounted for 75.5% of the total number of aquatic plants. The aquatic plants transplanted artificially were dominated by emerged plants (accounted for 69.2%), while those naturally developed were predominated by hygrophilous plants (accounted for 47.2%). The horizontal distribution of aquatic plant community in SCW was mixed in the form of mosaics, which made up typical association complex. Except association Aeschynomene indica L., the dominant species of other associations were all those transplanted artificially. The naturally grown species scattered throughout the SCW and only occupied a small percentage. A marked difference was detected on the species and species richness of aquatic plants in different regions of SCW. Biomass of aquatic plant associations in SCW was 167.7 t. SCW has shown a trend of succession heading for quick increase of plant diversity at the primary operation stage. This trend provides a good material base for the future stable community of aquatic plants in SCW. According to the current status of aquatic plants, some suggestions were put forward on the further optimization and utilization of aquatic plant systems in SCW.

  4. Medicinal plants for primary dysmenorrhoea: A systematic review.

    PubMed

    Pellow, Janice; Nienhuis, Chantelle

    2018-04-01

    Primary dysmenorrhoea is a common complaint experienced by many females in their reproductive years. The use of medicinal plants in the treatment of various gynaecological conditions is on the increase, despite the limited evidence available regarding efficacy and safety of their use. The aim of this systematic review was to synthesise the most recent evidence relating to the treatment of primary dysmenorrhoea with medicinal plants. A thorough database search was conducted using defined search terms, and randomised controlled trials (RCTs) published in English between 2008 and 2016, pertaining to the use of medicinal plants (single use) for the treatment of primary dysmenorrhoea, were assessed. Studies evaluating dysmenorrhoeal pain and associated symptoms as a primary or secondary outcome were considered and assessed by two reviewers independently of each other, using the JADAD scale and the Cochrane risk of bias tool,. 22 RCTs were included in the review; 9 were placebo-controlled trials and 13 were comparative studies to pharmacological treatment or nutritional supplements. Most of the evaluated medicinal plants showed evidence of efficacy in relieving menstrual pain in at least one RCT. The low or unclear quality of the majority of these studies however warrants caution in interpreting these results. This review adds to the knowledge-base on the use of these medicinal plants in the treatment of primary dysmenorrhoea. Further research is needed before definitive conclusions can be made regarding the efficacy and safety of the use of these medicinal plants. Copyright © 2018 Elsevier Ltd. All rights reserved.

  5. Co-synergism of endophyte Penicillium resedanum LK6 with salicylic acid helped Capsicum annuum in biomass recovery and osmotic stress mitigation

    PubMed Central

    2013-01-01

    Background Water-deficiency adversely affects crop growth by generating reactive oxygen species (ROS) at cellular level. To mitigate such stressful events, it was aimed to investigate the co-synergism of exogenous salicylic acid (SA) and symbiosis of endophytic fungus with Capsicum annuum L. (pepper). Results The findings of the study showed that exogenous SA (10-6 M) application to endophyte (Penicillium resedanum LK6) infected plants not only increased the shoot length and chlorophyll content but also improved the biomass recovery of pepper plants under polyethylene glycol (15%) induced osmotic stress (2, 4 and 8 days). Endophyte-infected plants had low cellular injury and high photosynthesis rate. SA also enhanced the colonization rate of endophyte in the host-plant roots. Endophyte and SA, in combination, reduced the production of ROS by increasing the total polyphenol, reduce glutathione, catalase, peroxidase and polyphenol oxidase as compared to control plants. Osmotic stress pronounced the lipid peroxidation and superoxide anions formation in control plants as compared to endophyte and SA-treated plants. The endogenous SA contents were significantly higher in pepper plants treated with endophyte and SA under osmotic stress as compared to control. Conclusion Endophytic fungal symbiosis and exogenous SA application can help the plants to relieve the adverse effects of osmotic stress by decreasing losses in biomass as compared to non-inoculated plants. These findings suggest that SA application positively impact microbial colonization while in combination, it reprograms the plant growth under various intervals of drought stress. Such symbiotic strategy can be useful for expanding agriculture production in drought prone lands. PMID:23452409

  6. 'To prove this is the industry's best hope': big tobacco's support of research on the genetics of nicotine addiction.

    PubMed

    Gundle, Kenneth R; Dingel, Molly J; Koenig, Barbara A

    2010-06-01

    New molecular techniques focus a genetic lens upon nicotine addiction. Given the medical and economic costs associated with smoking, innovative approaches to smoking cessation and prevention must be pursued; but can sound research be manipulated by the tobacco industry? The chronological narrative of this paper was created using iterative reviews of primary sources (the Legacy Tobacco Documents), supplemented with secondary literature to provide a broader context. The empirical data inform an ethics and policy analysis of tobacco industry-funded research. The search for a genetic basis for smoking is consistent with industry's decades-long plan to deflect responsibility away from the tobacco companies and onto individuals' genetic constitutions. Internal documents reveal long-standing support for genetic research as a strategy to relieve the tobacco industry of its legal responsibility for tobacco-related disease. Industry may turn the findings of genetics to its own ends, changing strategy from creating a 'safe' cigarette to defining a 'safe' smoker.

  7. The dying neonate: family-centered end-of-life care.

    PubMed

    De Lisle-Porter, Martine; Podruchny, Ann Marie

    2009-01-01

    There is a need in the NICU for an end-of-life care guideline that nurses can follow when working with dying infants and their families. Maintaining intravenous access to relieve the infant's pain, communicating sensitively to the family, and creating precious, everlasting memories are goals that should be part of every dying infant's care. The nurse's ability to partner with the family in caring for the infant is integral to helping the family take the first steps in their grief journey. Evidence-based literature provides NICU nurses with the knowledge that they are the facilitators of end-of-life care for dying infants. New mothers and fathers are not aware of the caring parental tasks they can perform for their dying baby. They look to and depend on their infant's nurses to encourage them. The guideline included here provides nurses with a tool for ensuring that families have the opportunity to create memories that will not only help them with their immediate pain, but also comfort them for a lifetime.

  8. The trigeneration cycle as a way to create multipurpose stationary power plants based on conversion of aeroderivative turbofan engines

    NASA Astrophysics Data System (ADS)

    Varaksin, A. Yu.; Arbekov, A. N.; Inozemtsev, A. A.

    2014-10-01

    A schematic cycle is considered, and thermodynamic analysis is performed to substantiate the possibility of creating multipurpose industrial power plants, operating on a trigeneration cycle, based on production-type turbofan engines.

  9. Use of the Internet to Obtain Drugs without a Prescription Among Treatment-involved Adolescents and Young Adults*

    PubMed Central

    Festinger, David S.; Dugosh, Karen L.; Clements, Nicolle; Flynn, Anna B.; Falco, Mathea; McLellan, A. Thomas; Arria, Amelia M.

    2016-01-01

    Nonmedical use of prescription drugs is common and poses risks such as injury, overdose, and development of abuse and dependence. Internet pharmacies offer prescription drugs without a prescription, creating a source of illicit drugs accessible to anyone with an Internet connection. We examined this issue in a convenience sample of 1,860 adolescents and young adults from 24 residential and outpatient treatment programs. Few individuals obtained drugs from the Internet (n = 26, 2.3%). Pain relievers were the most frequently purchased type of drug. The majority of adolescents and young adult online purchasers made the purchases from their own or a friend’s house. PMID:28194089

  10. Being Sexually Attracted to Minors: Sexual Development, Coping With Forbidden Feelings, and Relieving Sexual Arousal in Self-Identified Pedophiles.

    PubMed

    Houtepen, Jenny A B M; Sijtsema, Jelle J; Bogaerts, Stefan

    2016-01-02

    This article aims to provide more insight into pedophilic attraction and risk and protective factors for offending in nonclinical pedophiles. Fifteen participants were interviewed about sexuality, coping, and sexual self-regulation. Many participants struggled with acknowledging pedophilic interest in early puberty and experienced psychological difficulties as a result. Furthermore, many committed sex offenses during adolescence when they were still discovering their feelings. Early recognition of risk factors and early start of interventions seem vital in preventing offending. Moreover, results suggest that risk for offending can be diminished by creating more openness about pedophilia and by providing pedophiles with social support and control.

  11. [Theory analysis and clinical application of spirit-regulating and pain-relieving acupuncture method].

    PubMed

    Chen, Liang; Tang, Lewei; Du, Huaibin; Zheng, Hui; Liang, Fanrong

    2015-04-01

    The theoretical foundation and scientific connotation of spirit-regulating and pain-relieving acupuncture method as well as its clinical application for pain are discussed. During spirit regulation, attention should be paid on regulating heart and brain, while acupoints should be selected mainly from the Heart Meridian, Pericardium Meridian and Governor Vessel. It has significant efficacy for refractory pain in clinical treatment. Spirit-regulating and pain-relieving acupuncture method is development of acupuncture treating spirit, and it is an important method for pain in clinic. Improvement on sensitization of pain center and brain function is considered as one of the mechanisms in spirit-regulating and pain-relieving acupuncture method.

  12. Implementing the PAIN RelieveIt Randomized Controlled Trial in Hospice Care: Mechanisms for Success and Meeting PCORI Methodology Standards.

    PubMed

    Ezenwa, Miriam O; Suarez, Marie L; Carrasco, Jesus D; Hipp, Theresa; Gill, Anayza; Miller, Jacob; Shea, Robert; Shuey, David; Zhao, Zhongsheng; Angulo, Veronica; McCurry, Timothy; Martin, Joanna; Yao, Yingwei; Molokie, Robert E; Wang, Zaijie Jim; Wilkie, Diana J

    2017-07-01

    This purpose of this article is to describe how we adhere to the Patient-Centered Outcomes Research Institute's (PCORI) methodology standards relevant to the design and implementation of our PCORI-funded study, the PAIN RelieveIt Trial. We present details of the PAIN RelieveIt Trial organized by the PCORI methodology standards and components that are relevant to our study. The PAIN RelieveIt Trial adheres to four PCORI standards and 21 subsumed components. The four standards include standards for formulating research questions, standards associated with patient centeredness, standards for data integrity and rigorous analyses, and standards for preventing and handling missing data. In the past 24 months, we screened 2,837 cancer patients and their caregivers; 874 dyads were eligible; 223.5 dyads consented and provided baseline data. Only 55 patients were lost to follow-up-a 25% attrition rate. The design and implementation of the PAIN RelieveIt Trial adhered to PCORI's methodology standards for research rigor.

  13. 2-Fluoro-L-Fucose Is a Metabolically Incorporated Inhibitor of Plant Cell Wall Polysaccharide Fucosylation

    PubMed Central

    Wallace, Ian S.

    2015-01-01

    The monosaccharide L-fucose (L-Fuc) is a common component of plant cell wall polysaccharides and other plant glycans, including the hemicellulose xyloglucan, pectic rhamnogalacturonan-I (RG-I) and rhamnogalacturonan-II (RG-II), arabinogalactan proteins, and N-linked glycans. Mutations compromising the biosynthesis of many plant cell wall polysaccharides are lethal, and as a result, small molecule inhibitors of plant cell wall polysaccharide biosynthesis have been developed because these molecules can be applied at defined concentrations and developmental stages. In this study, we characterize novel small molecule inhibitors of plant fucosylation. 2-fluoro-L-fucose (2F-Fuc) analogs caused severe growth phenotypes when applied to Arabidopsis seedlings, including reduced root growth and altered root morphology. These phenotypic defects were dependent upon the L-Fuc salvage pathway enzyme L-Fucose Kinase/ GDP-L-Fucose Pyrophosphorylase (FKGP), suggesting that 2F-Fuc is metabolically converted to the sugar nucleotide GDP-2F-Fuc, which serves as the active inhibitory molecule. The L-Fuc content of cell wall matrix polysaccharides was reduced in plants treated with 2F-Fuc, suggesting that this molecule inhibits the incorporation of L-Fuc into these polysaccharides. Additionally, phenotypic defects induced by 2F-Fuc treatment could be partially relieved by the exogenous application of boric acid, suggesting that 2F-Fuc inhibits RG-II biosynthesis. Overall, the results presented here suggest that 2F-Fuc is a metabolically incorporated inhibitor of plant cellular fucosylation events, and potentially suggest that other 2-fluorinated monosaccharides could serve as useful chemical probes for the inhibition of cell wall polysaccharide biosynthesis. PMID:26414071

  14. The Sesquiterpenes(E)-ß-Farnesene and (E)-α-Bergamotene Quench Ozone but Fail to Protect the Wild Tobacco Nicotiana attenuata from Ozone, UVB, and Drought Stresses

    PubMed Central

    Palmer-Young, Evan C.; Veit, Daniel; Gershenzon, Jonathan; Schuman, Meredith C.

    2015-01-01

    Among the terpenes, isoprene (C5) and monoterpene hydrocarbons (C10) have been shown to ameliorate abiotic stress in a number of plant species via two proposed mechanisms: membrane stabilization and direct antioxidant effects. Sesquiterpene hydrocarbons (C15) not only share the structural properties thought to lend protective qualities to isoprene and monoterpene hydrocarbons, but also react rapidly with ozone, suggesting that sesquiterpenes may similarly enhance tolerance of abiotic stresses. To test whether sesquiterpenes protect plants against ozone, UVB light, or drought, we used transgenic lines of the wild tobacco Nicotiana attenuata. The transgenic plants expressed a maize terpene synthase gene (ZmTPS10) which produced a blend of (E)-ß-farnesene and (E)-α-bergamotene, or a point mutant of the same gene (ZmTPS10M) which produced (E)-ß-farnesene alone,. (E)-ß-farnesene exerted a local, external, and transient ozone-quenching effect in ozone-fumigated chambers, but we found no evidence that enhanced sesquiterpene production by the plant inhibited oxidative damage, or maintained photosynthetic function or plant fitness under acute or chronic stress. Although the sesquiterpenes (E)-ß-farnesene and (E)-α-bergamotene might confer benefits under intermittent heat stress, which was not tested, any roles in relieving abiotic stress may be secondary to their previously demonstrated functions in biotic interactions. PMID:26030663

  15. Chinese herbal medicine for chronic neck pain due to cervical degenerative disc disease.

    PubMed

    Cui, Xuejun; Trinh, Kien; Wang, Yong-Jun

    2010-01-20

    Chronic neck pain with radicular signs or symptoms is a common condition. Many patients use complementary and alternative medicine, including traditional Chinese medicine, to address their symptoms. To assess the efficacy of Chinese herbal medicines in treating chronic neck pain with radicular signs or symptoms. We electronically searched CENTRAL (The Cochrane Library 2009, issue 3), MEDLINE, EMBASE, CINAHL and AMED (beginning to October 1, 2009), the Chinese Biomedical Database and related herbal medicine databases in Japan and South Korea (1979 to 2007). We also contacted content experts and handsearched a number of journals published in China. We included randomized controlled trials with adults with a clinical diagnosis of cervical degenerative disc disease, cervical radiculopathy or myelopathy supported by appropriate radiological findings. The interventions were Chinese herbal medicines, defined as products derived from raw or refined plants or parts of plants, minerals and animals that are used for medicinal purposes in any form. The primary outcome was pain relief, measured with a visual analogue scale, numeric scale or other validated tool. The data were independently extracted and recorded by two review authors on a pre-developed form. Risk of bias and clinical relevance were assessed separately by two review authors using the twelve criteria and the five questions recommended by the Cochrane Back Review Group. Disagreements were resolved by consensus. All four included studies were in Chinese; two of which were unpublished. Effect sizes were not clinically relevant and there was low quality evidence for all outcomes due to study limitations and sparse data (single studies). Two trials (680 participants) found that Compound Qishe Tablets relieved pain better in the short-term than either placebo or Jingfukang; one trial (60 participants) found than an oral herbal formula of Huangqi ((Radix Astragali)18 g, Dangshen (Radix Codonopsis) 9 g, Sanqi (Radix Notoginseng) 9 g, Chuanxiong (Rhizoma Chuanxiong)12 g, Lujiao (Cornu Cervi Pantotrichum) 12 g, and Zhimu (Rhizoma Anemarrhenae)12 g) relieved pain better than Mobicox or Methycobal and one trial (360 participants) showed that a topical herbal medicine, Compound Extractum Nucis Vomicae, relieved pain better than Diclofenac Diethylamine Emulgel. There is low quality evidence that an oral herbal medication, Compound Qishe Tablet, reduced pain more than placebo or Jingfukang and a topical herbal medicine, Compound Extractum Nucis Vomicae, reduced pain more than Diclofenac Diethylamine Emulgel. Further research is very likely to change both the effect size and our confidence in the results.

  16. The iPlant collaborative: cyberinfrastructure for plant biology

    USDA-ARS?s Scientific Manuscript database

    The iPlant Collaborative (iPlant) is a United States National Science Foundation (NSF)funded project that aims to create an innovative, comprehensive, and foundational cyberinfrastructure in support of plant biology research (PSCIC, 2006). iPlant is developing cyberinfrastructure that uniquely enabl...

  17. Method of forming a stress relieved amorphous tetrahedrally-coordinated carbon film

    DOEpatents

    Friedmann, Thomas A.; Sullivan, John P.

    2000-01-01

    A stress-relieved amorphous-diamond film is formed by depositing an amorphous diamond film with specific atomic structure and bonding on to a substrate, and annealing the film at sufficiently high temperature to relieve the compressive stress in said film without significantly softening said film. The maximum annealing temperature is preferably on the order of 650.degree. C., a much lower value than is expected from the annealing behavior of other materials.

  18. Getting the Best Value in a Source Selection

    DTIC Science & Technology

    2015-12-01

    leadership, for both civilian and military program managers . Army COL James C. Mills relieved COL Gary D. Stephens as project manager for the...Precision Fires Rocket and Missile Systems (PFRMS) on July 15. COL William D. Jackson relieved COL Thomas H. Todd as project manager for Utility...Helicopters (UH) on July 15. COL Shane N. Fullmer relieved COL John Cavedo, Jr. as project manager for Joint Program Office, Joint Light Tactical Vehicles

  19. Electrical and mechanical characteristics of fully transparent IZO thin-film transistors on stress-relieving bendable substrates

    NASA Astrophysics Data System (ADS)

    Park, Sukhyung; Cho, Kyoungah; Oh, Hyungon; Kim, Sangsig

    2016-10-01

    In this study, we report the electrical and mechanical characteristics of fully transparent indium zinc oxide (IZO) thin-film transistors (TFTs) fabricated on stress-relieving bendable substrates. An IZO TFT on a stress-relieving substrate can operate normally at a bending radius of 6 mm, while an IZO TFT on a normal plastic substrate fails to operate normally at a bending radius of 15 mm. A plastic island with high Young's modulus embedded on a soft elastomer layer with low Young's modulus plays the role of a stress-relieving substrate for the operation of the bent IZO TFT. The stress and strain distributions over the IZO TFT will be analyzed in detail in this paper.

  20. Joint enhancement of lead accumulation in Brassica plants by EDTA and ammonium sulfate in sand culture.

    PubMed

    Xiong, Zhi-ting; Lu, Ping

    2002-04-01

    When EDTA was added alone in the Pb-contaminated sand, the plant biomass and the total Pb amount in Plant decreased in both species, Brassica pekinensis and B. juncea var. multiceps, though the shoot Pb amount increased. In contrast, when (NH4)2SO4 was added alone in the Pb-contaminated sand, little effect was observed on the shoot Pb amount, though the root Pb amount was significantly increased in B. juncea var. multiceps. When amending EDTA and (NH4)2SO4 in combination, however, the shoot Pb amount in both species substantially increased, being, on an average, 2 times and 9 times higher than that in EDTA alone or (NH4)2SO4 alone amended treatment, respectively. The two amendments showed antagonism for plant growth, but synergism for Pb bioaccumulation. B. pekinensis showed its highest level of shoot and total Pb amount in the treatment amended with EDTA and (NH4)2SO4 only a half as much as in the other treatments. It is inferred that the mechanisms responsible for the joint-enhanced Pb accumulation might be concerned with the acidification of the growth medium, cation exchange reaction and relieving EDTA induced toxicity as results by amending ammonium sulfate.

  1. Chemically Induced Conditional Rescue of the Reduced Epidermal Fluorescence8 Mutant of Arabidopsis Reveals Rapid Restoration of Growth and Selective Turnover of Secondary Metabolite Pools1[C][OPEN

    PubMed Central

    Kim, Jeong Im; Ciesielski, Peter N.; Donohoe, Bryon S.; Chapple, Clint; Li, Xu

    2014-01-01

    The phenylpropanoid pathway is responsible for the biosynthesis of diverse and important secondary metabolites including lignin and flavonoids. The reduced epidermal fluorescence8 (ref8) mutant of Arabidopsis (Arabidopsis thaliana), which is defective in a lignin biosynthetic enzyme p-coumaroyl shikimate 3′-hydroxylase (C3′H), exhibits severe dwarfism and sterility. To better understand the impact of perturbation of phenylpropanoid metabolism on plant growth, we generated a chemically inducible C3′H expression construct and transformed it into the ref8 mutant. Application of dexamethasone to these plants greatly alleviates the dwarfism and sterility and substantially reverses the biochemical phenotypes of ref8 plants, including the reduction of lignin content and hyperaccumulation of flavonoids and p-coumarate esters. Induction of C3′H expression at different developmental stages has distinct impacts on plant growth. Although early induction effectively restored the elongation of primary inflorescence stem, application to 7-week-old plants enabled them to produce new rosette inflorescence stems. Examination of hypocotyls of these plants revealed normal vasculature in the newly formed secondary xylem, presumably restoring water transport in the mutant. The ref8 mutant accumulates higher levels of salicylic acid than the wild type, but depletion of this compound in ref8 did not relieve the mutant’s growth defects, suggesting that the hyperaccumulation of salicylic acid is unlikely to be responsible for dwarfism in this mutant. PMID:24381065

  2. Testing the impact of a multimedia video CD of patient-controlled analgesia on pain knowledge and pain relief in patients receiving surgery.

    PubMed

    Chen, Hsing-Hsia; Yeh, Mei-Ling; Yang, Hui-Ju

    2005-07-01

    This study aimed to develop a multimedia video CD (VCD) of patient-controlled analgesia (PCA) and test its effects on pain knowledge and pain relief in patients receiving surgery. This multimedia VCD of PCA was created to convey fundamental knowledge to both patients and their family members and help patients properly utilize PCA devices to relieve pain and improve recovery. The content of multimedia VCD of PCA included pre-admission pain education, introduction of PCA, nursing care procedures, and questions and answers. This study used a quasi-experimental research design to test effects of the multimedia education program in the experimental group of 30 subjects compared to the control subjects of equal number (without the multimedia VCD of PCA). (1) The intervention of multimedia VCD of PCA resulted in a statistically significant difference in pain knowledge between the experimental and control groups. (2) Subjects in the experimental group obtained a better outcome of pain relief compared to control subjects. (3) Subjects in the experimental group indicated that the multimedia VCD of PCA indeed helped them effectively operate their PCA devices to relieve surgery pain. The clinical application of the multimedia VCD of PCA could help patients improve knowledge on pain, learn how to use PCA devices, achieve proper pain relief, and increase effectiveness of recovery activities.

  3. Genomic Aspects of Research Involving Polyploid Plants

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Yang, Xiaohan; Ye, Chuyu; Tschaplinski, Timothy J

    2011-01-01

    Almost all extant plant species have spontaneously doubled their genomes at least once in their evolutionary histories, resulting in polyploidy which provided a rich genomic resource for evolutionary processes. Moreover, superior polyploid clones have been created during the process of crop domestication. Polyploid plants generated by evolutionary processes and/or crop domestication have been the intentional or serendipitous focus of research dealing with the dynamics and consequences of genome evolution. One of the new trends in genomics research is to create synthetic polyploid plants which provide materials for studying the initial genomic changes/responses immediately after polyploid formation. Polyploid plants are alsomore » used in functional genomics research to study gene expression in a complex genomic background. In this review, we summarize the recent progress in genomics research involving ancient, young, and synthetic polyploid plants, with a focus on genome size evolution, genomics diversity, genomic rearrangement, genetic and epigenetic changes in duplicated genes, gene discovery, and comparative genomics. Implications on plant sciences including evolution, functional genomics, and plant breeding are presented. It is anticipated that polyploids will be a regular subject of genomics research in the foreseeable future as the rapid advances in DNA sequencing technology create unprecedented opportunities for discovering and monitoring genomic and transcriptomic changes in polyploid plants. The fast accumulation of knowledge on polyploid formation, maintenance, and divergence at whole-genome and subgenome levels will not only help plant biologists understand how plants have evolved and diversified, but also assist plant breeders in designing new strategies for crop improvement.« less

  4. Mangrove plantation over a limestone reef - Good for the ecology?

    NASA Astrophysics Data System (ADS)

    Asaeda, Takashi; Barnuevo, Abner; Sanjaya, Kelum; Fortes, Miguel D.; Kanesaka, Yoshikazu; Wolanski, Eric

    2016-05-01

    There have been efforts to restore degraded tropical and subtropical mangrove forests. While there have been many failures, there have been some successes but these were seldom evaluated to test to what level the created mangrove wetlands reproduce the characteristics of the natural ecosystem and thus what ecosystem services they can deliver. We provide such a detailed assessment for the case of Olango and Banacon Islands in the Philippines where the forest was created over a limestone reef where mangroves did not exist in one island but they covered most of the other island before deforestation in the 1940s and 1950s. The created forest appears to have reached a steady state after 60 years. As is typical of mangrove rehabilitation efforts worldwide, planting was limited to a single Rhizophora species. While a forest has been created, it does not mimic a natural forest. There is a large difference between the natural and planted forests in terms of forest structure and species diversity, and tree density. The high density of planted trees excludes importing other species from nearby natural forests; therefore the planted forest remains mono-specific even after several decades and shows no sign of mimicking the characteristics of a natural forest. The planted forests provided mangrove propagules that invaded nearby natural forests. The planted forest has also changed the substratum from sandy to muddy. The outline of the crown of the planted forest has become smooth and horizontal, contrary to that of a natural forest, and this changes the local landscape. Thus we recommend that future mangrove restoration schemes should modify their methodology in order to plant several species, maintain sufficient space between trees for growth, include the naturally dominant species, and create tidal creeks, in order to reproduce in the rehabilitated areas some of the key ecosystem characteristics of natural mangrove forests.

  5. Evidence for direct water absorption by shallow-rooted desert plants in desert-oasis ecotone, Northwest China

    NASA Astrophysics Data System (ADS)

    Fang, Jing

    2014-05-01

    Besides the absorption by roots from the soil substrate, it has long been known that plants exhibit alternative water-absorption strategies, particularly in drought-prone environments. For many tropical epiphytic orchids, air moisture can be absorbed directly by aerial roots. Some conifers are also found to utilize air moisture by foliar absorption during the summer fog season. However, few studies have been carried out on the atmospheric water vapor absorption by shallow-rooted desert plants. We conducted experiments in desert-oasis ecotone and investigated the effects of dew absorbed by three kinds of shallow-rooted seedlings on net photosynthesis rate, as well as on other water relations variables. Three kinds of typical shallow-rooted desert species (Bassia dasyphylla, Salsola collina and Corispermum declinatum) have been chosen and potted. Each species were subjected to contrasting watering regimes (normal and deficient) and different air moisture conditions (having dew and having no dew) for 10 weeks. Net photosynthesis rate was measured on six occasions during the study. Other water relations variables (midday shoot water potential, relative water content, stomatal conductance) were also measured. Under the dew conditions, average net photosynthesis rate, shoot water potential, leaf relative water content and stomatal conductance increased, with greater responses observed for plants subjected to a deficient watering regime than for well-watered plants. These results indicated dew occurred in arid region could be utilized through foliar absorption by some shallow-rooted plants, and for the shallow-rooted plants, the presence of dew could significantly relieve the deficit of water in water-stressed regime.

  6. Stomach Disorders

    MedlinePlus

    ... stomach at one time or another. Indigestion and heartburn are common problems. You can relieve some stomach ... you have a bowel movement Severe abdominal pain Heartburn not relieved by antacids Unintended weight loss Ongoing ...

  7. Choline Magnesium Trisalicylate

    MedlinePlus

    Choline magnesium trisalicylate is used to relieve the pain, tenderness, inflammation (swelling), and stiffness caused by arthritis ... also used to relieve pain and lower fever. Choline magnesium trisalicylate is in a class of nonsteroidal ...

  8. Etodolac

    MedlinePlus

    Etodolac tablets, capsules, and extended-release (long-acting) tablets are used to relieve pain, tenderness, swelling, and stiffness caused ... swelling of the lining of the joints). Etodolac tablets and capsules are also used to relieve pain ...

  9. Butabarbital

    MedlinePlus

    ... staying asleep). It is also used to relieve anxiety, including anxiety before surgery. Butabarbital is in a class of ... for sleep. When butabarbital is used to relieve anxiety before surgery, it is usually taken 60 to ...

  10. Cannabis and Anti-Cancer Drugs: Societal Usage and Expected Pharmacological Interactions - A Review.

    PubMed

    Bouquié, Régis; Deslandes, Guillaume; Mazaré, Hélène; Cogné, Marion; Mahé, Julien; Grégoire, Matthieu; Jolliet, Pascale

    2018-04-16

    Cannabis is a plant that has been used for centuries to relieve a wide range of symptoms. Since the 1960s, interest in medical research into this plant has grown steadily. Already very popular for recreational use, a growing number of consumers not accustomed to using cannabis for psychoactive purposes, have begun to use it as an alternative or complement to mainstream pharmaceutical medicines. The principal unsubstantiated or "social" uses of cannabis are based mainly on data that is at best controversial, but usually not scientifically proven. The aim of this review is to identify the scientific basis and reasons that lead patients with cancer to consume cannabis, and also to identify whether there is a risk of interaction between cannabis and anti-cancer medicines through drug transporters (P-glycoprotein and other ABC-superfamily members) Cytochromes P450 (3A, 1A, 2B, 2C 2D families…) and glucuronyl-transferases. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.

  11. Linking mitochondrial bioenergetics to insulin resistance via redox biology

    PubMed Central

    Fisher-Wellman, Kelsey H.; Neufer, P. Darrell

    2012-01-01

    Chronic overnutrition and physical inactivity are major risk factors for insulin resistance and type 2 diabetes. Recent research indicates that overnutrition generates an increase in hydrogen peroxide (H2O2) emission from mitochondria, serving as a release valve to relieve the reducing pressure created by fuel overload, as well as a primary signal to ultimately decrease insulin sensitivity. H2O2 is a major input to cellular redox circuits that link to cysteine residues throughout the entire proteome to regulate cell function. Here we review the principles of mitochondrial bioenergetics and redox systems biology and offer new insight as to how H2O2 emission may be linked via redox biology to the etiology of insulin resistance. PMID:22305519

  12. Photoexcitation Cascade and Quantum-Relativistic Jets in Graphene

    NASA Astrophysics Data System (ADS)

    Lewandowski, Cyprian; Levitov, L. S.

    2018-02-01

    In Dirac materials linear band dispersion blocks momentum-conserving interband transitions, creating a bottleneck for electron-hole pair production and carrier multiplication in the photoexcitation cascade. Here we show that the decays are unblocked and the bottleneck is relieved by subtle many-body effects involving multiple off-shell e -h pairs. The decays result from a collective behavior due to simultaneous emission of many soft pairs. We discuss characteristic signatures of the off-shell pathways, in particular the sharp angular distribution of secondary carriers, resembling relativistic jets in high-energy physics. The jets can be directly probed using solid-state equivalent of particle detectors. Collinear scattering enhances carrier multiplication, allowing for emission of as many as ˜10 secondary carriers per single absorbed photon.

  13. Inspiring hope in our rehabilitation patients, their families, and ourselves.

    PubMed

    Kautz, Donald

    2008-01-01

    When confronted with a devastating disability or chronic illness, rehabilitation nurses play a key role in inspiring hope for patients and their families. This article examines strategies nurses can implement in everyday practice: creating an environment of hope in a rehabilitation unit; assisting patients to manage their negative feelings about their disability; relieving chronic neuropathic pain; sustaining patient relationships with staff and family; helping patients to forgive themselves and others; enhancing patient intimacy with others; using literature to promote hope; acknowledging a patient's belief that nothing is impossible; using humor therapeutically; and maintaining hope for the moment. It is the moment-the time we spend with our patients-that is essential. In that moment, we are promoting hope.

  14. Intracutaneous sterile water for back pain in labour.

    PubMed Central

    Reynolds, J. L.

    1994-01-01

    Intracutaneous sterile water appears to be a simple, effective, and harmless technique for relieving back pain. This technique has been used to relieve pain of renal colic, whiplash, and back pain in labour. Family doctors often practise obstetrics in small or isolated units that have limited options for pain relief in labour. This technique is simple, is easy to learn, and appears effective for relieving back pain, which complicates about one third of all labours. Images Figures 1-2 Figures 3-4 PMID:7950471

  15. Diclofenac Topical (osteoarthritis pain)

    MedlinePlus

    ... gel (Voltaren) is used to relieve pain from osteoarthritis (arthritis caused by a breakdown of the lining ... Diclofenac topical liquid (Pennsaid) is used to relieve osteoarthritis pain in the knees. Diclofenac is in a ...

  16. Natural selection on plant physiological traits in an urban environment

    NASA Astrophysics Data System (ADS)

    Lambrecht, Susan C.; Mahieu, Stephanie; Cheptou, Pierre-Olivier

    2016-11-01

    Current rates of urbanization are creating new opportunities for studying urban plant ecology, but our knowledge of urban plant physiology lags behind that of other ecosystems. Moreover, higher temperatures, elevated CO2, and increased inorganic nitrogen deposition along with altered moisture regimes of urban as compared to rural areas creates a compelling analog for studying adaptations of plants to climate change. We grew plants under common conditions in a greenhouse to determine whether populations of Crepis sancta (Asteraceae) differed in phenological, morphological, and physiological traits. We also used a field experiment to test for natural selection on these traits in urban Montpellier, France. Urban plants flowered and senesced later than rural plants, and natural selection favored later phenology in the urban habitat. Natural selection also favored larger plants with more leaves, and increased photosynthesis and leaf nitrogen concentration. Ours is the first study to document selection on plant functional traits in an urban habitat and, as such, advances our understanding of urban plant ecology and possible adaptations to climate change.

  17. Phytochemicals, antioxidant, and anthelmintic activity of selected traditional wild edible plants of lower Assam.

    PubMed

    Swargiary, Ananta; Daimari, Abhijita; Daimari, Manita; Basumatary, Noymi; Narzary, Ezekiel

    2016-01-01

    Clerodendrum viscosum , Eryngium foetidum , Lippia javanica , and Murraya koenigii are one among the common wild edible plants in Northeast India which are also used as antidiabetic, stomach-ache relieving drugs, etc., The present study was aimed to reveal the phytochemical, antioxidant, and anthelmintic activity of the plants. The antioxidant capacity of methanolic extract of plants was studied by 1,1-diphenyl-2-picrylhydrazyl (DPPH), ferric reducing antioxidant power, TBARS, and total antioxidant activity (TAA). Total phenolics, flavonoids, Vitamin C, carbohydrate, and protein are also estimated following standard protocols. Anthelmintic activity of the extracts has also been studied in vitro against trematode parasites. The result showed that the methanolic extracts of plants possess a substantial quantity of alkaloids, phenolics, flavonoids, proteins, carbohydrates, and Vitamin C. Phenolics, flavonoids, and Vitamin C contents were found higher in C. viscosum followed by M. koenigii , L. javanica , and E. foetidum . The in vitro antioxidant assays revealed substantial free radical scavenging property in all the plants. TAA increased in the order C. viscosum > M. koenigii > L. javanica > E. foetidum . Similarly, C. viscosum displayed a better antioxidant capacity with IC 50 values 29.74 ± 3.63 μg and 148.77 ± 18.38 μg for DPPH and thiobarbituric acid reactive species, respectively. In addition, the plant extracts also showed good anthelmintic activity against Paramphistomum sp. Time taken for paralysis and death were 0:56 ± 0:09 h and 1:35 ± 0:07 h for L. javanica at 50 mg/mL concentration. The study therefore suggests the importance of tested plants as a natural source of free radical scavenger and plausible veterinary uses.

  18. Utilization of a high-throughput shoot imaging system to examine the dynamic phenotypic responses of a C4 cereal crop plant to nitrogen and water deficiency over time

    PubMed Central

    Neilson, E. H.; Edwards, A. M.; Blomstedt, C. K.; Berger, B.; Møller, B. Lindberg; Gleadow, R. M.

    2015-01-01

    The use of high-throughput phenotyping systems and non-destructive imaging is widely regarded as a key technology allowing scientists and breeders to develop crops with the ability to perform well under diverse environmental conditions. However, many of these phenotyping studies have been optimized using the model plant Arabidopsis thaliana. In this study, The Plant Accelerator® at The University of Adelaide, Australia, was used to investigate the growth and phenotypic response of the important cereal crop, Sorghum bicolor L. Moench and related hybrids to water-limited conditions and different levels of fertilizer. Imaging in different spectral ranges was used to monitor plant composition, chlorophyll, and moisture content. Phenotypic image analysis accurately measured plant biomass. The data set obtained enabled the responses of the different sorghum varieties to the experimental treatments to be differentiated and modelled. Plant architectural instead of architecture elements were determined using imaging and found to correlate with an improved tolerance to stress, for example diurnal leaf curling and leaf area index. Analysis of colour images revealed that leaf ‘greenness’ correlated with foliar nitrogen and chlorophyll, while near infrared reflectance (NIR) analysis was a good predictor of water content and leaf thickness, and correlated with plant moisture content. It is shown that imaging sorghum using a high-throughput system can accurately identify and differentiate between growth and specific phenotypic traits. R scripts for robust, parsimonious models are provided to allow other users of phenomic imaging systems to extract useful data readily, and thus relieve a bottleneck in phenotypic screening of multiple genotypes of key crop plants. PMID:25697789

  19. Exogenous NO depletes Cd-induced toxicity by eliminating oxidative damage, re-establishing ATPase activity, and maintaining stress-related hormone equilibrium in white clover plants.

    PubMed

    Liu, S L; Yang, R J; Pan, Y Z; Wang, M H; Zhao, Y; Wu, M X; Hu, J; Zhang, L L; Ma, M D

    2015-11-01

    Various nitric oxide (NO) regulators [including the NO donor sodium nitroprusside (SNP), the NO scavenger 2-(4-carboxyphenyl)-4,4,5,5-tetramethylimidazoline-1-oxyl-3-oxide (cPTIO), the NO-synthase inhibitor N (G)-nitro-L-Arg-methyl ester (L-NAME), and the SNP analogues sodium nitrite/nitrate and sodium ferrocyanide] were investigated to elucidate the role of NO in white clover (Trifolium repens L.) plants after long-term (5 days) exposure to cadmium (Cd). A dose of 100 μM Cd stress significantly restrained plant growth and decreased the concentrations of chlorophyll and NO in vivo, whereas it disrupted the balance of stress-related hormones and enhanced the accumulation of Cd, thereby inducing reactive oxygen species (ROS) burst. However, the inhibition of plant growth was relieved by 50 μM SNP through its stimulation of ROS-scavenging compounds (ascorbic acid, ascorbate peroxidase, catalase, glutathione reductase, non-protein thiol, superoxide dismutase, and total glutathione), regulation of H(+)-ATPase activity of proton pumps, and increasing jasmonic acid and proline but decreasing ethylene in plant tissues. Even so, the alleviating effect of SNP on plant growth was counteracted by cPTIO and L-NAME and was not observed with SNP analogues, suggesting that the protective roles of SNP are related to the induction of NO. These results suggest that NO may improve the Cd tolerance of white clover plants by eliminating oxidative damage, re-establishing ATPase activity, and maintaining hormone equilibrium. Improving our understanding of the role of NO in white clover plants is key to expanding the plantations to various regions and the recovery of pasture species in the future.

  20. Creating Stiff, Tough, and Functional Hydrogel Composites with Low-Melting-Point Alloys.

    PubMed

    Takahashi, Riku; Sun, Tao Lin; Saruwatari, Yoshiyuki; Kurokawa, Takayuki; King, Daniel R; Gong, Jian Ping

    2018-04-01

    Reinforcing hydrogels with a rigid scaffold is a promising method to greatly expand the mechanical and physical properties of hydrogels. One of the challenges of creating hydrogel composites is the significant stress that occurs due to swelling mismatch between the water-swollen hydrogel matrix and the rigid skeleton in aqueous media. This stress can cause physical deformation (wrinkling, buckling, or fracture), preventing the fabrication of robust composites. Here, a simple yet versatile method is introduced to create "macroscale" hydrogel composites, by utilizing a rigid reinforcing phase that can relieve stress-induced deformation. A low-melting-point alloy that can transform from a load-bearing solid state to a free-deformable liquid state at relatively low temperature is used as a reinforcing skeleton, which enables the release of any swelling mismatch, regardless of the matrix swelling degree in liquid media. This design can generally provide hydrogels with hybridized functions, including excellent mechanical properties, shape memory, and thermal healing, which are often difficult or impossible to achieve with single-component hydrogel systems. Furthermore, this technique enables controlled electrochemical reactions and channel-structure templating in hydrogel matrices. This work may play an important role in the future design of soft robots, wearable electronics, and biocompatible functional materials. © 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  1. An Evaluative Review of Simulated Dynamic Smart 3d Objects

    NASA Astrophysics Data System (ADS)

    Romeijn, H.; Sheth, F.; Pettit, C. J.

    2012-07-01

    Three-dimensional (3D) modelling of plants can be an asset for creating agricultural based visualisation products. The continuum of 3D plants models ranges from static to dynamic objects, also known as smart 3D objects. There is an increasing requirement for smarter simulated 3D objects that are attributed mathematically and/or from biological inputs. A systematic approach to plant simulation offers significant advantages to applications in agricultural research, particularly in simulating plant behaviour and the influences of external environmental factors. This approach of 3D plant object visualisation is primarily evident from the visualisation of plants using photographed billboarded images, to more advanced procedural models that come closer to simulating realistic virtual plants. However, few programs model physical reactions of plants to external factors and even fewer are able to grow plants based on mathematical and/or biological parameters. In this paper, we undertake an evaluation of plant-based object simulation programs currently available, with a focus upon the components and techniques involved in producing these objects. Through an analytical review process we consider the strengths and weaknesses of several program packages, the features and use of these programs and the possible opportunities in deploying these for creating smart 3D plant-based objects to support agricultural research and natural resource management. In creating smart 3D objects the model needs to be informed by both plant physiology and phenology. Expert knowledge will frame the parameters and procedures that will attribute the object and allow the simulation of dynamic virtual plants. Ultimately, biologically smart 3D virtual plants that react to changes within an environment could be an effective medium to visually represent landscapes and communicate land management scenarios and practices to planners and decision-makers.

  2. TRANSGENIC PLANTS: ENVIRONMENTAL PERSISTENCE AND EFFECTS ON SOIL AND PLANT ECOSYSTEMS

    EPA Science Inventory

    The genetic engineering of plants has facilitated the production of valuable agricultural and forestry crops. Transgenic plants have been created that have increased resistance to pests, herbicides, pathogens, and environmental stress, enhanced qualitative and quantitative trait...

  3. Hemorrhoids

    MedlinePlus

    ... ice packs to relieve swelling. Use acetaminophen (1 brand name: Tylenol), ibuprofen (1 brand name: Motrin), or aspirin to help relieve pain. ... Childbirth Women Men Seniors Your Health Resources Healthcare Management End-of-Life Issues Insurance & Bills Self Care ...

  4. SVC obstruction

    MedlinePlus

    The goal of treatment is to relieve the blockage. Diuretics (water pills) or steroids (anti-inflammtory drugs) may be used to temporarily relieve swelling . Other treatment options may include radiation or chemotherapy to shrink the tumor, or surgery to ...

  5. Non-prescribed use of pain relievers among adolescents in the United States.

    PubMed

    Wu, Li-Tzy; Pilowsky, Daniel J; Patkar, Ashwin A

    2008-04-01

    We examined gender-specific prevalences, patterns, and correlates of non-prescribed use of pain relievers - mainly opioids - in a representative sample of American adolescents (N=18,678). Data were drawn from the public use data file of the 2005 U.S. National Survey on Drug Use and Health, a survey of non-institutionalized American household residents. The patterns of non-prescribed use of prescription pain relievers were examined, and logistic regression procedures were conducted to identify correlates of non-prescribed use. Approximately one in 10 adolescents aged 12-17 years reported non-prescribed use of pain relievers in their lifetime (9.3% in males and 10.3% in females). The mean age of first non-prescribed use was 13.3 years, which was similar to the mean age of first use of alcohol and marijuana but older than the age of first inhalant use. Among all non-prescribed users, 52% reported having used hydrocodone products (Vicodin, Lortab, Lorcet, and Lorcet Plus, and hydrocodone), 50% had used propoxyphene (Darvocet or Darvon) or codeine (Tylenol with codeine), and 24% had used oxycodone products (OxyContin, Percocet, Percodan, and Tylox). Approximately one quarter (26%) of all non-prescribed users had never used other non-prescribed or illicit drugs. There were gender variations in correlates of non-prescribed use. Use of non-prescribed pain relievers occurs early in adolescence. Research is needed to understand whether early use of non-prescribed pain relievers is related to later drug use.

  6. Large-Eddy Simulation of Wind-Plant Aerodynamics: Preprint

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Churchfield, M. J.; Lee, S.; Moriarty, P. J.

    In this work, we present results of a large-eddy simulation of the 48 multi-megawatt turbines composing the Lillgrund wind plant. Turbulent inflow wind is created by performing an atmospheric boundary layer precursor simulation and turbines are modeled using a rotating, variable-speed actuator line representation. The motivation for this work is that few others have done wind plant large-eddy simulations with a substantial number of turbines, and the methods for carrying out the simulations are varied. We wish to draw upon the strengths of the existing simulations and our growing atmospheric large-eddy simulation capability to create a sound methodology for performingmore » this type of simulation. We have used the OpenFOAM CFD toolbox to create our solver.« less

  7. Plant materials for riparian revegetation

    Treesearch

    J. Chris Hoag; Thomas D. Landis

    2002-01-01

    Increased public awareness and concern have prompted new efforts in riparian revegetation using streambank bioengineering techniques. Planting in a riparian zone is very different than planting on upland sites. Riparian planting zones should be used to ensure that the vegetation is planted in the appropriate location so that the planting does not create more problems...

  8. Nuclear Power Plants | RadTown USA | US EPA

    EPA Pesticide Factsheets

    2018-06-22

    Nuclear power plants produce electricity from the heat created by splitting uranium atoms. In the event of a nuclear power plant emergency, follow instructions from emergency responders and public officials.

  9. Treatment Option Overview (Thyroid Cancer)

    MedlinePlus

    ... cancer, but can relieve symptoms and improve the quality of life . Treatment may include the following: For tumors that ... palliative therapy to relieve symptoms and improve the quality of life . Chemotherapy . A clinical trial of a targeted therapy . ...

  10. Stages of Thyroid Cancer

    MedlinePlus

    ... cancer, but can relieve symptoms and improve the quality of life . Treatment may include the following: For tumors that ... palliative therapy to relieve symptoms and improve the quality of life . Chemotherapy . A clinical trial of a targeted therapy . ...

  11. NIH Pain Consortium

    MedlinePlus

    ... Did You Know? Infographics on Pain Topics Resource Library Health Care Systems Research Collaboratory Pain Registries IOM Report: Relieving Pain ... Did You Know? Infographics on Pain Topics Resource Library Health Care Systems Research Collaboratory Pain Registries IOM Report: Relieving Pain ...

  12. “To Prove This is the Industry’s Best Hope”: Big Tobacco’s Support of Research on the Genetics of Nicotine Addiction

    PubMed Central

    Gundle, Kenneth R.; Dingel, Molly J.

    2010-01-01

    Background New molecular techniques focus a genetic lens on nicotine addiction. Given the medical and economic costs associated with smoking, innovative approaches to smoking cessation and prevention must be pursued. But can sound research be manipulated by the tobacco industry? Methodology The chronological narrative of this paper was created using iterative reviews of primary sources (the Legacy Tobacco Documents), supplemented with secondary literature to provide broader context. The empirical data inform an ethics and policy analysis of tobacco-industry funded research. Findings The search for a genetic basis for smoking is consistent with industry’s decades-long plan to deflect responsibility away from the tobacco companies and onto individuals’ genetic constitutions. Internal documents reveal longstanding support for genetic research as a strategy to relieve the tobacco industry of its legal responsibility for tobacco-related disease. Conclusions Industry may turn the findings of genetics to its own ends, changing strategy from creating a “safe” cigarette to defining a “safe” smoker. PMID:20659058

  13. Narrowing of the Coronary Sinus: A Device-Based Therapy for Persistent Angina Pectoris.

    PubMed

    Konigstein, Maayan; Verheye, Stefan; Jolicœur, E Marc; Banai, Shmuel

    2016-01-01

    Alongside the remarkable advances in medical and invasive therapies for the treatment of ischemic heart disease, an increasing number of patients with advanced coronary artery disease unsuitable for revascularization continue to suffer from angina pectoris despite optimal medical therapy. Patients with chronic angina have poor quality of life and increased levels of anxiety and depression. A considerable number of innovative therapeutic modalities for the treatment of chronic angina have been investigated over the years; however, none of these therapeutic options has become a standard of care, and none are widely utilized. Current treatment options for refractory angina focus on medical therapy and secondary risk factor modification. Interventions to create increased pressure in the coronary sinus may alleviate myocardial ischemia by forcing redistribution of coronary blood flow from the less ischemic subepicardium to the more ischemic subendocardium, thus relieving symptoms of ischemia. Percutaneous, transvenous implantation of a balloon expandable, hourglass-shaped, stainless steel mesh in the coronary sinus to create a fixed focal narrowing and to increase backwards pressure, may serve as a new device-based therapy destined for the treatment of refractory angina pectoris.

  14. Foliar water uptake: a common water acquisition strategy for plants of the redwood forest.

    PubMed

    Limm, Emily Burns; Simonin, Kevin A; Bothman, Aron G; Dawson, Todd E

    2009-09-01

    Evaluations of plant water use in ecosystems around the world reveal a shared capacity by many different species to absorb rain, dew, or fog water directly into their leaves or plant crowns. This mode of water uptake provides an important water subsidy that relieves foliar water stress. Our study provides the first comparative evaluation of foliar uptake capacity among the dominant plant taxa from the coast redwood ecosystem of California where crown-wetting events by summertime fog frequently occur during an otherwise drought-prone season. Previous research demonstrated that the dominant overstory tree species, Sequoia sempervirens, takes up fog water by both its roots (via drip from the crown to the soil) and directly through its leaf surfaces. The present study adds to these early findings and shows that 80% of the dominant species from the redwood forest exhibit this foliar uptake water acquisition strategy. The plants studied include canopy trees, understory ferns, and shrubs. Our results also show that foliar uptake provides direct hydration to leaves, increasing leaf water content by 2-11%. In addition, 60% of redwood forest species investigated demonstrate nocturnal stomatal conductance to water vapor. Such findings indicate that even species unable to absorb water directly into their foliage may still receive indirect benefits from nocturnal leaf wetting through suppressed transpiration. For these species, leaf-wetting events enhance the efficacy of nighttime re-equilibration with available soil water and therefore also increase pre-dawn leaf water potentials.

  15. Correlates of Abusing and Misusing Over-the-Counter Pain Relievers Among Adult Population of Wrocław (Poland).

    PubMed

    Wójta-Kempa, Monika; Krzyżanowski, Dominik M

    2016-01-01

    Almost 90% of households in Poland buy medicines on their own initiative. The most popular OTC medicines bought by Polish consumers are painkillers and non-steroid-anti-inflammatory drugs. The aim of this article was to recognize and describe the most important predictive factors of the abuse and misuse of over-the-counter pain relievers among adults in Wrocław (Poland). The groups of users were selected and described. Some examples of misuse were analyzed. Three hundred eighty six adult inhabitants of Wrocław took part in the survey. The quota sample was representative referring to the most important socio-demographic factors (sex and median age). Almost 91% of participants declare taking OTC pain relievers, and 1.3% of them are their daily users. Only 6.2% of adult inhabitants of Wrocław never take OTC pain relievers. The category of "heavy users" embraces 11% of participants. The most important risk factors of overusing OTC pain relievers are sex (female), age over 55 years and the low health status. Only half of participants read the box label regularly and 25% of users admit they have modified recommended doses. Over 60% shortened recommended intervals between doses and 16% took two or more different pain medications (containing different substances). The non-medical purposes of using OTC pain relievers were: tiredness (7%), stressful situations (5.4%), and discomfort (18.4%). Some users take pain medications to cure hangovers (26%), or instead of the appropriate medicine (7%). About 20% take pain medications without a doctor's advice for longer than the recommended 3 days, and 10% never consult taking such medications with doctors. Pain should be treated aggressively and successfully, especially among chronically ill patients. We should monitor the consumption of OTC pain relievers and limit their current excessively supply and high availability.

  16. Agroecology: Implications for plant response to climate change

    USDA-ARS?s Scientific Manuscript database

    Agricultural ecosystems (agroecosystems) represent the balance between the physiological responses of plants and plant canopies and the energy exchanges. Rising temperature and increasing CO2 coupled with an increase in variability of precipitation will create a complex set of interactions on plant ...

  17. Needs Assessment of a Major Metropolitan Reliever Airport

    DOT National Transportation Integrated Search

    1998-01-01

    In November and December of 1994, investigators from Southern Illinois University, Carbondale, conducted a survey of based-users and transient-users of Palwaukee Municipal Airport of Wheeling, Illinois. Palwaukee is designated as a reliever airport b...

  18. Treatment Options by Stage (Thyroid Cancer)

    MedlinePlus

    ... cancer, but can relieve symptoms and improve the quality of life . Treatment may include the following: For tumors that ... palliative therapy to relieve symptoms and improve the quality of life . Chemotherapy . A clinical trial of a targeted therapy . ...

  19. Know Concentration Before Giving Acetaminophen to Infants

    MedlinePlus

    ... Pain Reliever and Triaminic Infants’ Syrup Fever Reducer Pain Reliever. There are also store brands on the shelves. December 22, 2011 ... or Cold Don't Need Medicines Codeine and Tramadol Can Cause Breathing Problems for Children Reducing Fever ...

  20. Contribution of transposable elements in the plant's genome.

    PubMed

    Sahebi, Mahbod; Hanafi, Mohamed M; van Wijnen, Andre J; Rice, David; Rafii, M Y; Azizi, Parisa; Osman, Mohamad; Taheri, Sima; Bakar, Mohd Faizal Abu; Isa, Mohd Noor Mat; Noor, Yusuf Muhammad

    2018-07-30

    Plants maintain extensive growth flexibility under different environmental conditions, allowing them to continuously and rapidly adapt to alterations in their environment. A large portion of many plant genomes consists of transposable elements (TEs) that create new genetic variations within plant species. Different types of mutations may be created by TEs in plants. Many TEs can avoid the host's defense mechanisms and survive alterations in transposition activity, internal sequence and target site. Thus, plant genomes are expected to utilize a variety of mechanisms to tolerate TEs that are near or within genes. TEs affect the expression of not only nearby genes but also unlinked inserted genes. TEs can create new promoters, leading to novel expression patterns or alternative coding regions to generate alternate transcripts in plant species. TEs can also provide novel cis-acting regulatory elements that act as enhancers or inserts within original enhancers that are required for transcription. Thus, the regulation of plant gene expression is strongly managed by the insertion of TEs into nearby genes. TEs can also lead to chromatin modifications and thereby affect gene expression in plants. TEs are able to generate new genes and modify existing gene structures by duplicating, mobilizing and recombining gene fragments. They can also facilitate cellular functions by sharing their transposase-coding regions. Hence, TE insertions can not only act as simple mutagens but can also alter the elementary functions of the plant genome. Here, we review recent discoveries concerning the contribution of TEs to gene expression in plant genomes and discuss the different mechanisms by which TEs can affect plant gene expression and reduce host defense mechanisms. Copyright © 2018 Elsevier B.V. All rights reserved.

  1. A Gibberellin-Mediated DELLA-NAC Signaling Cascade Regulates Cellulose Synthesis in Rice.

    PubMed

    Huang, Debao; Wang, Shaogan; Zhang, Baocai; Shang-Guan, Keke; Shi, Yanyun; Zhang, Dongmei; Liu, Xiangling; Wu, Kun; Xu, Zuopeng; Fu, Xiangdong; Zhou, Yihua

    2015-06-01

    Cellulose, which can be converted into numerous industrial products, has important impacts on the global economy. It has long been known that cellulose synthesis in plants is tightly regulated by various phytohormones. However, the underlying mechanism of cellulose synthesis regulation remains elusive. Here, we show that in rice (Oryza sativa), gibberellin (GA) signals promote cellulose synthesis by relieving the interaction between SLENDER RICE1 (SLR1), a DELLA repressor of GA signaling, and NACs, the top-layer transcription factors for secondary wall formation. Mutations in GA-related genes and physiological treatments altered the transcription of CELLULOSE SYNTHASE genes (CESAs) and the cellulose level. Multiple experiments demonstrated that transcription factors NAC29/31 and MYB61 are CESA regulators in rice; NAC29/31 directly regulates MYB61, which in turn activates CESA expression. This hierarchical regulation pathway is blocked by SLR1-NAC29/31 interactions. Based on the results of anatomical analysis and GA content examination in developing rice internodes, this signaling cascade was found to be modulated by varied endogenous GA levels and to be required for internode development. Genetic and gene expression analyses were further performed in Arabidopsis thaliana GA-related mutants. Altogether, our findings reveal a conserved mechanism by which GA regulates secondary wall cellulose synthesis in land plants and provide a strategy for manipulating cellulose production and plant growth. © 2015 American Society of Plant Biologists. All rights reserved.

  2. Photoperiodic regulation of the C-repeat binding factor (CBF) cold acclimation pathway and freezing tolerance in Arabidopsis thaliana.

    PubMed

    Lee, Chin-Mei; Thomashow, Michael F

    2012-09-11

    The CBF (C-repeat binding factor) pathway has a major role in plant cold acclimation, the process whereby certain plants increase in freezing tolerance in response to low nonfreezing temperatures. In Arabidopsis thaliana, the pathway is characterized by rapid cold induction of CBF1, CBF2, and CBF3, which encode transcriptional activators, followed by induction of CBF-targeted genes that impart freezing tolerance. At warm temperatures, CBF transcript levels are low, but oscillate due to circadian regulation with peak expression occurring at 8 h after dawn (zeitgeber time 8; ZT8). Here, we establish that the CBF pathway is also regulated by photoperiod at warm temperatures. At ZT8, CBF transcript levels in short-day (SD; 8-h photoperiod) plants were three- to fivefold higher than in long-day plants (LD; 16-h photoperiod). Moreover, the freezing tolerance of SD plants was greater than that of LD plants. Genetic analysis indicated that phytochrome B (PHYB) and two phytochrome-interacting factors, PIF4 and PIF7, act to down-regulate the CBF pathway and freezing tolerance under LD conditions. Down-regulation of the CBF pathway in LD plants correlated with higher PIF4 and PIF7 transcript levels and greater stability of the PIF4 and PIF7 proteins under LD conditions. Our results indicate that during the warm LD growing season, the CBF pathway is actively repressed by PHYB, PIF4, and PIF7, thus mitigating allocation of energy and nutrient resources toward unneeded frost protection. This repression is relieved by shortening day length resulting in up-regulation of the CBF pathway and increased freezing tolerance in preparation for coming cold temperatures.

  3. Photoperiodic regulation of the C-repeat binding factor (CBF) cold acclimation pathway and freezing tolerance in Arabidopsis thaliana

    PubMed Central

    Lee, Chin-Mei; Thomashow, Michael F.

    2012-01-01

    The CBF (C-repeat binding factor) pathway has a major role in plant cold acclimation, the process whereby certain plants increase in freezing tolerance in response to low nonfreezing temperatures. In Arabidopsis thaliana, the pathway is characterized by rapid cold induction of CBF1, CBF2, and CBF3, which encode transcriptional activators, followed by induction of CBF-targeted genes that impart freezing tolerance. At warm temperatures, CBF transcript levels are low, but oscillate due to circadian regulation with peak expression occurring at 8 h after dawn (zeitgeber time 8; ZT8). Here, we establish that the CBF pathway is also regulated by photoperiod at warm temperatures. At ZT8, CBF transcript levels in short-day (SD; 8-h photoperiod) plants were three- to fivefold higher than in long-day plants (LD; 16-h photoperiod). Moreover, the freezing tolerance of SD plants was greater than that of LD plants. Genetic analysis indicated that phytochrome B (PHYB) and two phytochrome-interacting factors, PIF4 and PIF7, act to down-regulate the CBF pathway and freezing tolerance under LD conditions. Down-regulation of the CBF pathway in LD plants correlated with higher PIF4 and PIF7 transcript levels and greater stability of the PIF4 and PIF7 proteins under LD conditions. Our results indicate that during the warm LD growing season, the CBF pathway is actively repressed by PHYB, PIF4, and PIF7, thus mitigating allocation of energy and nutrient resources toward unneeded frost protection. This repression is relieved by shortening day length resulting in up-regulation of the CBF pathway and increased freezing tolerance in preparation for coming cold temperatures. PMID:22927419

  4. Interventions for heartburn in pregnancy

    PubMed Central

    Neilson, James P

    2014-01-01

    Background Heartburn is a common symptom in pregnancy affecting up to 80% of women in the third trimester. The reasons for the increase in symptoms in pregnancy are not well understood, but the effects of pregnancy hormones on the lower oesophageal sphincter and gastric clearance are thought to play a part. A range of interventions have been used to relieve symptoms including advice on diet and lifestyle, antacids, antihistamines, and proton pump inhibitors. The safety and effectiveness of these interventions to relieve heartburn in pregnancy have not been established. Objectives To assess the effect of interventions to relieve heartburn in pregnancy. Search methods We searched the Cochrane Pregnancy and Childbirth Group’s Trials Register (April 2008). We updated this search on 10 November 2012 and added the results to the awaiting classification section of the review. Selection criteria We included randomised controlled trials evaluating interventions to relieve heartburn. Data collection and analysis We assessed eligibility for inclusion and extracted data independently. Main results Three studies were eligible for inclusion, together they included a total of 286 women. All three were placebo controlled trials, each examining a different medication to relieve heartburn (intramuscular prostigmine, an antacid preparation and an antacid plus ranitidine). All three produced positive findings in favour of the intervention groups. It was not possible to pool findings from studies to produce an overall treatment effect. Authors’ conclusions There was little information to draw conclusions on the overall effectiveness of interventions to relieve heartburn in pregnancy. [Note: the two citations in the awaiting classification section of the review may alter the conclusions of the review once assessed.] PMID:18843742

  5. Plant growth response in experimental soilless mixes prepared from coal combustion products and organic waste materials

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bardhan, S.; Watson, M.; Dick, W.A.

    2008-07-15

    Large quantities of organic materials such as animal manures, yard trimmings, and biosolids are produced each year. Beneficial use options for them are often limited, and composting has been proposed as a way to better manage these organic materials. Similarly, burning of coal created 125 million tons of coal combustion products (CCP) in the United States in 2006. An estimated 53 million tons of CCP were reused, whereas the remainder was deposited in landfills. By combining CCP and composted organic materials (COM), we were able to create soilless plant growth mixes with physicochemical conditions that can support excellent plant growth.more » An additional benefit is the conservation of natural raw materials, such as peat, which is generally used for making soilless mixes. Experimental mixes were formulated by combining CCP and COM at ratios ranging from 2:8 to 8:2 (vol/vol), respectively. Water content at saturation for the created mixes was 63% to 72%, whereas for the commercial control, it was 77%. pH values for the best performing mixes ranged between 5.9 and 6.8. Electrical conductivity and concentrations of required plant nutrient were also within plant growth recommendations for container media. Significantly (P < 0.0001) higher plant biomass growth (7%-130%) was observed in the experimental mixes compared with a commercial mix. No additional fertilizers were provided during the experiment, and reduced fertilization costs can thus accrue as an added benefit to the grower. In summary, combining CCP and COM, derived from source materials often viewed as wastes, can create highly productive plant growth mixes.« less

  6. Stages of Mycosis Fungoides and the Sezary Syndrome

    MedlinePlus

    ... usually palliative , to relieve symptoms and improve the quality of life . Patients with early stage disease may live many ... as palliative therapy to relieve symptoms and improve quality of life . Sometimes, total skin electron beam (TSEB) radiation therapy ...

  7. Using Alcohol to Relieve Your Pain: What Are the Risks?

    MedlinePlus

    ... neuropathy, the most common neurologic complication associated with alcoholism. If you use alcohol to relieve your pain, ... Into Health ® National Institute on Alcohol Abuse and Alcoholism www.niaaa.nih.gov • 301.443.3860 Updated ...

  8. Plant height revertants of Dominant Semidwarf mutant rice created by low-energy ion irradiation

    NASA Astrophysics Data System (ADS)

    Liu, Binmei; Wu, Yuejin; Xu, Xue; Song, M.; Zhao, M.; Fu, X. D.

    2008-04-01

    Dominant Semidwarf mutant rice (Sdd) was obtained from its wild type (WT) by irradiation with a low-energy ion beam. Six tall revertants of Sdd were induced by irradiation. The revertants restored the plant height to that of WT plants. Investigation of the agronomic character and genetic analysis indicate that the revertants are similar to WT plants with putative different inherited mutations. The revertants were checked for DNA differences using the simple sequence repeat technique. Among 408 such primers used, only 2 primers detected mutation sites in the revertants, which provided the molecular evidence for the revertants induced from Sdd. This study indicates that ion irradiation may be used as a mutagen to create revertants for plant architecture studies and could be a new application.

  9. Flight tests show potential benefits of data link as primary communication medium

    NASA Technical Reports Server (NTRS)

    Scanlon, Charles H.; Knox, Charles E.

    1991-01-01

    Message exchange for air traffic control (ATC) purposes via data link offers the potential benefits of increasing the airspace system safety and efficiency. This is accomplished by reducing communication errors and relieving the overloaded ATC radio frequencies, which hamper efficient message exchanges during peak traffic periods in many busy terminal areas. However, the many uses and advantages of data link create additional questions concerning the interface among the human-users and the cockpit and ground systems. A flight test was conducted in the NASA Langley B-737 airplane to contrast flight operations using current voice communications with the use of data link for transmitting both strategic and tactical ATC clearances during a typical commercial airline flight from takeoff to landing. Commercial airplane pilots were used as test subjects.

  10. The value and benefits of the International Conference on Harmonisation to drug regulatory authorities: advancing harmonization for better public health.

    PubMed

    Molzon, J A; Giaquinto, A; Lindstrom, L; Tominaga, T; Ward, M; Doerr, P; Hunt, L; Rago, L

    2011-04-01

    The International Conference on Harmonisation (ICH) is an unparalleled undertaking, which has brought together drug regulatory authorities and pharmaceutical trade associations from Europe, Japan, and the United States, to discuss the scientific and technical aspects of medical product registration. Launched in 1990, the value and benefits of ICH to regulators are being realized. ICH has harmonized submission requirements and created a harmonized submission format that is relieving both companies and regulatory authorities of the burdens of assembling and reviewing separate submissions for each region. As more countries embrace ICH guidelines, we anticipate additional benefits, including the promotion of good review practices and, ultimately, a common regulatory language that will facilitate further interactions among global drug regulatory authorities.

  11. Acute intestinal obstruction due to metastatic lung cancer—case report

    PubMed Central

    2017-01-01

    Abstract We present a case of male patient, who was referred to our department because of acute intestinal obstruction, which was the initial clinical symptom of primary lung cancer. The abdominal computed tomography (CT) prior to the emergency operation showed small intestinal obstruction and metastases to both adrenal glands. The patient underwent an emergency abdominal exploratory laparotomy, that confirmed small bowel obstruction and diffuse metastatic lesions along the entire small bowel length. During the operation we took a sample of one metastasis for pathological examination and we created an intestinal bypass to relieve small bowel obstruction. The pathologist suspected to primary lung cancer according to the immunohistochemical staining. The chest CT after the emergency operation showed a large primary tumor in the left upper pulmonary lobe. PMID:28458837

  12. Ecosystem development after mangrove wetland creation: plant-soil change across a 20-year chronosequence

    USGS Publications Warehouse

    Osland, Michael J.; Spivak, Amanda C.; Nestlerode, Janet A.; Lessmann, Jeannine M.; Almario, Alejandro E.; Heitmuller, Paul T.; Russell, Marc J.; Krauss, Ken W.; Alvarez, Federico; Dantin, Darrin D.; Harvey, James E.; From, Andrew S.; Cormier, Nicole; Stagg, Camille L.

    2012-01-01

    Mangrove wetland restoration and creation efforts are increasingly proposed as mechanisms to compensate for mangrove wetland losses. However, ecosystem development and functional equivalence in restored and created mangrove wetlands are poorly understood. We compared a 20-year chronosequence of created tidal wetland sites in Tampa Bay, Florida (USA) to natural reference mangrove wetlands. Across the chronosequence, our sites represent the succession from salt marsh to mangrove forest communities. Our results identify important soil and plant structural differences between the created and natural reference wetland sites; however, they also depict a positive developmental trajectory for the created wetland sites that reflects tightly coupled plant-soil development. Because upland soils and/or dredge spoils were used to create the new mangrove habitats, the soils at younger created sites and at lower depths (10-30 cm) had higher bulk densities, higher sand content, lower soil organic matter (SOM), lower total carbon (TC), and lower total nitrogen (TN) than did natural reference wetland soils. However, in the upper soil layer (0-10 cm), SOM, TC, and TN increased with created wetland site age simultaneously with mangrove forest growth. The rate of created wetland soil C accumulation was comparable to literature values for natural mangrove wetlands. Notably, the time to equivalence for the upper soil layer of created mangrove wetlands appears to be faster than for many other wetland ecosystem types. Collectively, our findings characterize the rate and trajectory of above- and below-ground changes associated with ecosystem development in created mangrove wetlands; this is valuable information for environmental managers planning to sustain existing mangrove wetlands or mitigate for mangrove wetland losses.

  13. Treatment Options by Stage (Mycosis Fungoides and the Sezary Syndrome)

    MedlinePlus

    ... usually palliative , to relieve symptoms and improve the quality of life . Patients with early stage disease may live many ... as palliative therapy to relieve symptoms and improve quality of life . Sometimes, total skin electron beam (TSEB) radiation therapy ...

  14. Misuse of Prescription Pain Relievers: The Buzz Takes Your Breath Away. Permanently.

    MedlinePlus

    ... parents, doctors, relatives, teachers, or school guidance counselors. Substance abuse ruins lives. Don't let it happen to ... is hooked on prescription pain relievers, call the substance abuse treatment 24-hour helpline: 1.800.662.HELP ...

  15. Review of interventions to relieve postpartum pain from perineal trauma.

    PubMed

    Petersen, Melanie Robin

    2011-01-01

    As an increased risk for infection and potentially significant source of pain, perineal trauma can negatively impact a mother's postpartum recovery. A variety of nursing interventions aimed at relieving perineal pain are largely based on localized cooling. Unfortunately, these interventions may not follow best practice for providing adequate pain relief or preventing perineal postpartum infection. This article provides a review of the literature related to utilizing localized cooling for postpartum perineal pain relief, suggests clinical guidelines for safe implementation of these measures, and calls for further research for evidence of nursing interventions to relieve pain caused by perineal trauma.

  16. Outcomes of isolated glenoid labral injuries in professional baseball pitchers.

    PubMed

    Cerynik, Douglas L; Ewald, Timothy J; Sastry, Akhilesh; Amin, Nirav H; Liao, Jason G; Tom, James A

    2008-05-01

    Major League Baseball (MLB) pitchers who return to competition after labral surgery show a decline in their pitching performance. Retrospective cohort. Tertiary institution. MLB starting or relief pitchers with isolated glenoid labral injuries. Open or arthroscopic surgical repair of isolated glenoid labral injuries. Individual statistics were reviewed for 42 MLB pitchers who underwent surgical repair of isolated glenoid labral injuries of their throwing shoulder between 1998 and 2003. Pertinent statistical data, including earned run average (ERA), innings pitched (IP), and walks plus hits per inning pitched (WHIP), were obtained for all players and compared before and after surgery. These statistics were evaluated for an association with demographic factors, pitching role, and rehabilitation time. A total of 42 MLB pitchers (26 starters, 16 relievers) were included in the study with an average age of 27.5 years for starters and 29.9 years for relievers at injury time. There were 30 right-handed pitchers and 12 left-handed pitchers. In all, 69% of pitchers returned postoperatively to MLB for at least one season; 29% pitched for three seasons or more. For both relievers and starters, there was no statistically significant postoperative change in ERA or WHIP at 1 and 3 years. Starters had significantly decreased IP at 1 year, but not at 3 years. Relievers had no significant change in IP at 1 year postoperatively, but IP were significantly decreased at 3 years. Relievers missed less time after surgery than did starters (11.4 vs. 18.4 months). Most pitchers who were able to return to competition after surgery showed insignificant changes in ERA and WHIP and significant decreases in IP. Age, MLB experience, and pitching role as a reliever were the most significant factors related to a successful return after surgery.

  17. Understanding the development of roots exposed to contaminants and the potential of plant-associated bacteria for optimization of growth

    PubMed Central

    Remans, Tony; Thijs, Sofie; Truyens, Sascha; Weyens, Nele; Schellingen, Kerim; Keunen, Els; Gielen, Heidi; Cuypers, Ann; Vangronsveld, Jaco

    2012-01-01

    Background and Scope Plant responses to the toxic effects of soil contaminants, such as excess metals or organic substances, have been studied mainly at physiological, biochemical and molecular levels, but the influence on root system architecture has received little attention. Nevertheless, the precise position, morphology and extent of roots can influence contaminant uptake. Here, data are discussed that aim to increase the molecular and ecological understanding of the influence of contaminants on root system architecture. Furthermore, the potential of plant-associated bacteria to influence root growth by their growth-promoting and stress-relieving capacities is explored. Methods Root growth parameters of Arabidopsis thaliana seedlings grown in vertical agar plates are quantified. Mutants are used in a reverse genetics approach to identify molecular components underlying quantitative changes in root architecture after exposure to excess cadmium, copper or zinc. Plant-associated bacteria are isolated from contaminated environments, genotypically and phenotypically characterized, and used to test plant root growth improvement in the presence of contaminants. Key Results The molecular determinants of primary root growth inhibition and effects on lateral root density by cadmium were identified. A vertical split-root system revealed local effects of cadmium and copper on root development. However, systemic effects of zinc exposure on root growth reduced both the avoidance of contaminated areas and colonization of non-contaminated areas. The potential for growth promotion and contaminant degradation of plant-associated bacteria was demonstrated by improved root growth of inoculated plants exposed to 2,4-di-nitro-toluene (DNT) or cadmium. Conclusions Knowledge concerning the specific influence of different contaminants on root system architecture and the molecular mechanisms by which this is achieved can be combined with the exploitation of plant-associated bacteria to influence root development and increase plant stress tolerance, which should lead to more optimal root systems for application in phytoremediation or safer biomass production. PMID:22634257

  18. Understanding the development of roots exposed to contaminants and the potential of plant-associated bacteria for optimization of growth.

    PubMed

    Remans, Tony; Thijs, Sofie; Truyens, Sascha; Weyens, Nele; Schellingen, Kerim; Keunen, Els; Gielen, Heidi; Cuypers, Ann; Vangronsveld, Jaco

    2012-07-01

    Plant responses to the toxic effects of soil contaminants, such as excess metals or organic substances, have been studied mainly at physiological, biochemical and molecular levels, but the influence on root system architecture has received little attention. Nevertheless, the precise position, morphology and extent of roots can influence contaminant uptake. Here, data are discussed that aim to increase the molecular and ecological understanding of the influence of contaminants on root system architecture. Furthermore, the potential of plant-associated bacteria to influence root growth by their growth-promoting and stress-relieving capacities is explored. Root growth parameters of Arabidopsis thaliana seedlings grown in vertical agar plates are quantified. Mutants are used in a reverse genetics approach to identify molecular components underlying quantitative changes in root architecture after exposure to excess cadmium, copper or zinc. Plant-associated bacteria are isolated from contaminated environments, genotypically and phenotypically characterized, and used to test plant root growth improvement in the presence of contaminants. The molecular determinants of primary root growth inhibition and effects on lateral root density by cadmium were identified. A vertical split-root system revealed local effects of cadmium and copper on root development. However, systemic effects of zinc exposure on root growth reduced both the avoidance of contaminated areas and colonization of non-contaminated areas. The potential for growth promotion and contaminant degradation of plant-associated bacteria was demonstrated by improved root growth of inoculated plants exposed to 2,4-di-nitro-toluene (DNT) or cadmium. Knowledge concerning the specific influence of different contaminants on root system architecture and the molecular mechanisms by which this is achieved can be combined with the exploitation of plant-associated bacteria to influence root development and increase plant stress tolerance, which should lead to more optimal root systems for application in phytoremediation or safer biomass production.

  19. Carpal Tunnel Exercises: Can They Relieve Symptoms?

    MedlinePlus

    ... relieve symptoms, such as pain and numbness. These exercises are most effective when combined with other treatments, such as behavior changes or wrist splints, for mild to moderate carpal tunnel syndrome. If your symptoms ... exercises — one type of carpal tunnel exercise — might help ...

  20. Complex Regional Pain Syndrome

    MedlinePlus

    ... an anesthetic (pain reliever) into certain nerves. This blocks the pain signals. If the injection relieves the pain, it may be repeated. It is not a cure. Sympathectomy of the injured nerve. A surgeon will cut or clamp the nerve chain. This has been reported to improve pain caused ...

  1. INTERIOR DETAIL, SECONDSTORY JOISTS, SUBFLOORING, AND FIREPLACE HEARTH RELIEVING ARCH. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    INTERIOR DETAIL, SECOND-STORY JOISTS, SUBFLOORING, AND FIREPLACE HEARTH RELIEVING ARCH. THESE FEATURES WERE MADE VISIBLE AFTER A 2002 FAILURE OF WHAT WAS LIKELY THE ORIGINAL EIGHTEENTH-CENTURY CEILING PLASTER IN THE SOUTHWEST CABINET - The Woodlands, 4000 Woodlands Avenue, Philadelphia, Philadelphia County, PA

  2. A Review on Antiulcer Activity of Few Indian Medicinal Plants

    PubMed Central

    Vimala, G.; Gricilda Shoba, F.

    2014-01-01

    Ulcer is a common gastrointestinal disorder which is seen among many people. It is basically an inflamed break in the skin or the mucus membrane lining the alimentary tract. Ulceration occurs when there is a disturbance of the normal equilibrium caused by either enhanced aggression or diminished mucosal resistance. It may be due to the regular usage of drugs, irregular food habits, stress, and so forth. Peptic ulcers are a broad term that includes ulcers of digestive tract in the stomach or the duodenum. The formation of peptic ulcers depends on the presence of acid and peptic activity in gastric juice plus a breakdown in mucosal defenses. A number of synthetic drugs are available to treat ulcers. But these drugs are expensive and are likely to produce more side effects when compared to herbal medicines. The literature revealed that many medicinal plants and polyherbal formulations are used for the treatment of ulcer by various ayurvedic doctors and traditional medicinal practitioners. The ideal aims of treatment of peptic ulcer disease are to relieve pain, heal the ulcer, and delay ulcer recurrence. In this review attempts have been made to know about some medicinal plants which may be used in ayurvedic as well as modern science for the treatment or prevention of peptic ulcer. PMID:24971094

  3. Antinociceptive activity of Sempervivum tectorum L. extract in rats.

    PubMed

    Kekesi, Gabriella; Dobos, Ildiko; Benedek, György; Horvath, Gyöngyi

    2003-11-01

    The extract of Sempervivum tectorum L. (Crassulaceae) containing several flavonoids is widely used as an antiinflammatory agent in folk medicine. Previous studies have demonstrated that various flavonoids or flavonoid-containing plant extracts produce significant antinociception, but no data are available concerning their antinociceptive effect especially at the spinal level. The purpose of the present study was to investigate the antinociceptive activity of Sempervivum tectorum L. extract on acute and inflammatory pain sensitivity in awake rats. The pain sensitivity was assessed by the acute tail- flick test in intact rats and by the paw withdrawal test after carrageenan-induced inflammation using heat stimulus. The plant extract was administered intraperitoneally and intrathecally in rats. The intraperitoneal injection of a high dose of the extract (1000 mg/kg) significantly (p < 0.05) increased the paw withdrawal latency of the inflamed paw. The intrathecal administration (30-300 micro g) caused a small, but significant increase (10%-15%) in tail- flick latency. In the carrageenan-induced inflammatory model, the intrathecally applied extract (30-1000 micro g) significantly decreased, but did not relieve the thermal hyperalgesia. The results suggest that the spinal cord does not seem to play an important role in the antinociceptive effects of this plant extract. Copyright 2003 John Wiley & Sons, Ltd.

  4. Elements of Successful Plant Management.

    ERIC Educational Resources Information Center

    Sweitzer, John H.

    The physical plant administrator manages men, money and materials to create the best possible physical environment for the educational processes at his institution. Areas of concern of the plant administrator are administration, building maintenance, janitorial services, traffic, security and safety, utilities, grounds, alterations, and…

  5. Surgical resection of duodenal lymphangiectasia: A case report

    PubMed Central

    Chen, Chih-Ping; Chao, Yee; Li, Chung-Pin; Lo, Wen-Ching; Wu, Chew-Wun; Tsay, Shyh-Haw; Lee, Rheun-Chuan; Chang, Full-Young

    2003-01-01

    Intestinal lymphangiectasia, characterized by dilatation of intestinal lacteals, is rare. The major treatment for primary intestinal lymphangiectasia is dietary modification. Surgery to relieve symptoms and to clarify the etiology should be considered when medical treatment failed. This article reports a 49-year-old woman of solitary duodenal lymphangiectasia, who presented with epigastralgia and anemia. Her symptoms persisted with medical treatment. Surgery was finally performed to relieve the symptoms and to exclude the existence of underlying etiologies, with satisfactory effect. In conclusion, duodenal lymphangiectasia can present clinically as epigastralgia and chronic blood loss. Surgical resection may be resorted to relieve pain, control bleeding, and exclude underlying diseases in some patients. PMID:14669360

  6. Inhibitory effects of crude extracts from some edible Thai plants against replication of hepatitis B virus and human liver cancer cells

    PubMed Central

    2012-01-01

    Background Edible plants such as Cratoxylum formosum (Jack) Dyer, Curcumin longa Lin, Momordica charantia Lin and Moringa oleifera Lam have long been believed in Thai culture to relieve ulcers and the symptoms of liver disease. However, little is known about their anti-liver cancer properties and antiviral activity against hepatitis B virus (HBV). The aim of this study was to investigate the anti-liver cancer and anti-HBV activities of crude extracts from these edible plants on human liver cancer cells. Methods Plant samples were prepared and extracted using buffer and hydro-alcoholic solvents. The MTT assay was performed to investigate the effects of the plant extracts on the cell viability of HepG2 cells. The inhibitory effect on replication of HBV was analysed by determining the level of HBV covalently closed circular DNA (cccDNA) in transiently transfected HepG2 cells with the DNA expression plasmid of the HBV genome using a quantitative real-time PCR. Results Buffer and hydroalcoholic extracts from C. formosum (leaf) reduced cell viability of HepG2 cells and they also inhibited HBV cccDNA. Crude extracts from C. longa (bulb) in both solvents did not have any cytotoxic effects on the HepG2 cells, but they significantly decreased the level of HBV cccDNA. Buffer extracts from the leaves of M. charantia and the fruits of M. oleifera showed to have anti-HBV activity and also a mild cytotoxicity effect on the HepG2 cells. In addition, leaves of M. Oleifera extracted by hydroalcoholic solvent drastically decreased the level of cccDNA in transiently transfected HepG2 cells. Conclusion Some crude extracts of edible plants contain compounds that demonstrate anti-liver cancer and anti-HBV activities. PMID:23216691

  7. Rapamycin and Glucose-Target of Rapamycin (TOR) Protein Signaling in Plants*

    PubMed Central

    Xiong, Yan; Sheen, Jen

    2012-01-01

    Target of rapamycin (TOR) kinase is an evolutionarily conserved master regulator that integrates energy, nutrients, growth factors, and stress signals to promote survival and growth in all eukaryotes. The reported land plant resistance to rapamycin and the embryo lethality of the Arabidopsis tor mutants have hindered functional dissection of TOR signaling in plants. We developed sensitive cellular and seedling assays to monitor endogenous Arabidopsis TOR activity based on its conserved S6 kinase (S6K) phosphorylation. Surprisingly, rapamycin effectively inhibits Arabidopsis TOR-S6K1 signaling and retards glucose-mediated root and leaf growth, mimicking estradiol-inducible tor mutants. Rapamycin inhibition is relieved in transgenic plants deficient in Arabidopsis FK506-binding protein 12 (FKP12), whereas FKP12 overexpression dramatically enhances rapamycin sensitivity. The role of Arabidopsis FKP12 is highly specific as overexpression of seven closely related FKP proteins fails to increase rapamycin sensitivity. Rapamycin exerts TOR inhibition by inducing direct interaction between the TOR-FRB (FKP-rapamycin binding) domain and FKP12 in plant cells. We suggest that variable endogenous FKP12 protein levels may underlie the molecular explanation for longstanding enigmatic observations on inconsistent rapamycin resistance in plants and in various mammalian cell lines or diverse animal cell types. Integrative analyses with rapamycin and conditional tor and fkp12 mutants also reveal a central role of glucose-TOR signaling in root hair formation. Our studies demonstrate the power of chemical genetic approaches in the discovery of previously unknown and pivotal functions of glucose-TOR signaling in governing the growth of cotyledons, true leaves, petioles, and primary and secondary roots and root hairs. PMID:22134914

  8. Tamarisk coalition - native riparian plant materials program

    Treesearch

    Stacy Kolegas

    2012-01-01

    The Tamarisk Coalition (TC), a nonprofit organization dedicated to riparian restoration in the western United States, has created a Native Plant Materials Program to address the identified need for native riparian plant species for use in revegetation efforts on the Colorado Plateau. The specific components of the Native Plant Materials Program include: 1) provide seed...

  9. Plant vulnerabilities and genetic adaptation (Chapter 4)

    Treesearch

    Bryce A. Richardson; Nancy L. Shaw; Rosemary L. Pendleton

    2012-01-01

    The biogeography of plant species and population genetic structure within species is principally governed by climate. The association between climate change and plant distributions has been well documented since the last ice age, and recent studies have shown contemporary climate changes can create landscape-scale die-offs or movement of plant taxa. Terrestrial...

  10. The influence of linear elements on plant species diversity of Mediterranean rural landscapes: assessment of different indices and statistical approaches.

    PubMed

    García del Barrio, J M; Ortega, M; Vázquez De la Cueva, A; Elena-Rosselló, R

    2006-08-01

    This paper mainly aims to study the linear element influence on the estimation of vascular plant species diversity in five Mediterranean landscapes modeled as land cover patch mosaics. These landscapes have several core habitats and a different set of linear elements--habitat edges or ecotones, roads or railways, rivers, streams and hedgerows on farm land--whose plant composition were examined. Secondly, it aims to check plant diversity estimation in Mediterranean landscapes using parametric and non-parametric procedures, with two indices: Species richness and Shannon index. Land cover types and landscape linear elements were identified from aerial photographs. Their spatial information was processed using GIS techniques. Field plots were selected using a stratified sampling design according to relieve and tree density of each habitat type. A 50x20 m2 multi-scale sampling plot was designed for the core habitats and across the main landscape linear elements. Richness and diversity of plant species were estimated by comparing the observed field data to ICE (Incidence-based Coverage Estimator) and ACE (Abundance-based Coverage Estimator) non-parametric estimators. The species density, percentage of unique species, and alpha diversity per plot were significantly higher (p < 0.05) in linear elements than in core habitats. ICE estimate of number of species was 32% higher than of ACE estimate, which did not differ significantly from the observed values. Accumulated species richness in core habitats together with linear elements, were significantly higher than those recorded only in the core habitats in all the landscapes. Conversely, Shannon diversity index did not show significant differences.

  11. Transcriptomic Response of Purple Willow (Salix purpurea) to Arsenic Stress

    PubMed Central

    Yanitch, Aymeric; Brereton, Nicholas J. B.; Gonzalez, Emmanuel; Labrecque, Michel; Joly, Simon; Pitre, Frederic E.

    2017-01-01

    Arsenic (As) is a toxic element for plants and one of the most common anthropogenic pollutants found at contaminated sites. Despite its severe effects on plant metabolism, several species can accumulate substantial amounts of arsenic and endure the associated stress. However, the genetic mechanisms involved in arsenic tolerance remains obscure in many model plant species used for land decontamination (phytoremediation), including willows. The present study assesses the potential of Salix purpurea cv. ‘Fish Creek’ for arsenic phytoextraction and reveals the genetic responses behind arsenic tolerance, phytoextraction and metabolism. Four weeks of hydroponic exposure to 0, 5, 30 and 100 mg/L revealed that plants were able to tolerate up to 5 mg/L arsenic. Concentrations of 0 and 5 mg/L of arsenic treatment were then used to compare alterations in gene expression of roots, stems and leaves using RNA sequencing. Differential gene expression revealed transcripts encoding proteins putatively involved in entry of arsenic into the roots, storage in vacuoles and potential transport through the plant as well as primary and secondary (indirect) toxicity tolerance mechanisms. A major role for tannin as a compound used to relieve cellular toxicity is implicated as well as unexpected expression of the cadmium transporter CAX2, providing a potential means for internal arsenic mobility. These insights into the underpinning genetics of a successful phytoremediating species present novel opportunities for selection of dedicated arsenic tolerant crops as well as the potential to integrate such tolerances into a wider Salix ideotype alongside traits including biomass yield, biomass quality, low agricultural inputs and phytochemical production. PMID:28702037

  12. Korean Emotional Laborers' Job Stressors and Relievers: Focus on Work Conditions and Emotional Labor Properties.

    PubMed

    Lee, Garam

    2015-12-01

    The present study aims to investigate job stressors and stress relievers for Korean emotional laborers, specifically focusing on the effects of work conditions and emotional labor properties. Emotional laborers are asked to hide or distort their real emotions in their interaction with clients. They are exposed to high levels of stress in the emotional labor process, which leads to serious mental health risks including burnout, depression, and even suicide impulse. Exploring job stressors and relieving factors would be the first step in seeking alternatives to protect emotional laborers from those mental health risks. Using the third wave data of Korean Working Conditions Survey, logistic regression analysis was conducted for two purposes: to examine the relations of emotional labor and stress, and to find out job stressors and relievers for emotional laborers. The chances of stress arousal are 3.5 times higher for emotional laborers; emotional laborers experience double risk-burden for stress arousal. In addition to general job stressors, emotional laborers need to bear burdens related to emotional labor properties. The effect of social support at the workplace is not significant for stress relief, unlike common assumptions, whereas subjective satisfaction (wage satisfaction and work-life balance) is proven to have relieving effects on emotional laborers' job stress. From the results, the importance of a balanced understanding of emotional labor for establishing effective policies for emotional laborer protection is stressed.

  13. Effects of a continuous lateral turning device on pressure relief.

    PubMed

    Do, Nam Ho; Kim, Deog Young; Kim, Jung-Hoon; Choi, Jong Hyun; Joo, So Young; Kang, Na Kyung; Baek, Yoon Su

    2016-01-01

    [Purpose] The purpose of this study was to examine the pressure-relieving effects of a continuous lateral turning device on common pressure ulcer sites. [Subjects] Twenty-four healthy adults participated. [Methods] The design of our continuous lateral turning device was motivated by the need for an adequate pressure-relieving device for immobile and/or elderly people. The procedure of manual repositioning is embodied in our continuous lateral turning device. The interface pressure and time were measured, and comfort grade was evaluated during sessions of continuous lateral turning at 0°, 15°, 30°, and 45°. We quantified the pressure-relieving effect using peak pressure, mean pressure, and pressure time integration. [Results] Participants demonstrated pressure time integration values below the pressure-time threshold at 15°, 30°, and 45° at all the common pressure ulcer sites. Moreover, the most effective angles for pressure relief at the common pressure ulcer sites were 30° at the occiput, 15° at the left scapula, 45° at the right scapula, 45° at the sacrum, 15° at the right heel, and 30° at the left heel. However, angles greater than 30° induced discomfort. [Conclusion] Continuous lateral turning with our specially designed device effectively relieved the pressure of targeted sites. Moreover, the suggested angles of continuous lateral turning can be used to relieve pressure at targeted sites.

  14. Prescription Pain Reliever Abuse and Dependence among Adolescents: A Nationally Representative Study

    ERIC Educational Resources Information Center

    Wu, Li-Tzy; Ringwalt, Christopher L.; Mannelli, Paolo; Patkar, Ashwin A.

    2008-01-01

    The study investigates the prevalence, patterns, and correlates of adolescents' abuse, sub-threshold dependence, and dependence on prescription pain relievers (PPRs) in a nationally representative sample. Results show dependence on PPRs can take place without abuse and that sub-threshold dependence could have implications for major diagnostic…

  15. United States Coast Guard: Officer Corps Military Professional Development Program

    DTIC Science & Technology

    2011-06-10

    captain relieved of command after viewing porn on computer,‖ 10 July 2010, http://www.thenewstribune.com/2010/07/ 10/1259108/portland-coast-guard...Coast Guard captain relieved of command after viewing porn on computer,‖ 10 July 2010. http://www.thenewstribune.com/2010/07/ 10/1259108/portland

  16. 49 CFR 173.158 - Nitric acid.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ...” following the steel designation on containers subject to stress relieving or heat treatment during... nitric acid, the following are permissible: (A) Type 304 heat-treated (quenched in water at 1040 °C (1900 °F)), (B) Stabilized Type 347 in the as-welded condition, (C) Stabilized Type 347 stress-relieved...

  17. 49 CFR 173.158 - Nitric acid.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ...” following the steel designation on containers subject to stress relieving or heat treatment during... nitric acid, the following are permissible: (A) Type 304 heat-treated (quenched in water at 1040 °C (1900 °F)), (B) Stabilized Type 347 in the as-welded condition, (C) Stabilized Type 347 stress-relieved...

  18. 49 CFR 173.158 - Nitric acid.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ...” following the steel designation on containers subject to stress relieving or heat treatment during... nitric acid, the following are permissible: (A) Type 304 heat-treated (quenched in water at 1040 °C (1900 °F)), (B) Stabilized Type 347 in the as-welded condition, (C) Stabilized Type 347 stress-relieved...

  19. Kinetic mechanism of an aldehyde reductase of Saccharomyces cerevisiae that relieves toxicity of furfural and 5-hydroxymethylfurfural

    USDA-ARS?s Scientific Manuscript database

    An effective means of relieving the toxicity of furan aldehydes, furfural (FFA) and 5-hydroxymethylfurfural (HMF), on fermenting organisms is essential for achieving efficient fermentation of lignocellulosic biomass to ethanol and other products. Ari1p, an aldehyde reductase from Saccharomyces cerev...

  20. Healthful and Unhealthful Plant-Based Diets and the Risk of Coronary Heart Disease in U.S. Adults.

    PubMed

    Satija, Ambika; Bhupathiraju, Shilpa N; Spiegelman, Donna; Chiuve, Stephanie E; Manson, JoAnn E; Willett, Walter; Rexrode, Kathryn M; Rimm, Eric B; Hu, Frank B

    2017-07-25

    Plant-based diets are recommended for coronary heart disease (CHD) prevention. However, not all plant foods are necessarily beneficial for health. This study sought to examine associations between plant-based diet indices and CHD incidence. We included 73,710 women in NHS (Nurses' Health Study) (1984 to 2012), 92,329 women in NHS2 (1991 to 2013), and 43,259 men in Health Professionals Follow-up Study (1986 to 2012), free of chronic diseases at baseline. We created an overall plant-based diet index (PDI) from repeated semiquantitative food-frequency questionnaire data, by assigning positive scores to plant foods and reverse scores to animal foods. We also created a healthful plant-based diet index (hPDI) where healthy plant foods (whole grains, fruits/vegetables, nuts/legumes, oils, tea/coffee) received positive scores, whereas less-healthy plant foods (juices/sweetened beverages, refined grains, potatoes/fries, sweets) and animal foods received reverse scores. To create an unhealthful PDI (uPDI), we gave positive scores to less-healthy plant foods and reverse scores to animal and healthy plant foods. Over 4,833,042 person-years of follow-up, we documented 8,631 incident CHD cases. In pooled multivariable analysis, higher adherence to PDI was independently inversely associated with CHD (hazard ratio [HR] comparing extreme deciles: 0.92; 95% confidence interval [CI]: 0.83 to 1.01; p trend = 0.003). This inverse association was stronger for hDPI (HR: 0.75; 95% CI: 0.68 to 0.83; p trend <0.001). Conversely, uPDI was positively associated with CHD (HR: 1.32; 95% CI: 1.20 to 1.46; p trend <0.001). Higher intake of a plant-based diet index rich in healthier plant foods is associated with substantially lower CHD risk, whereas a plant-based diet index that emphasizes less-healthy plant foods is associated with higher CHD risk. Copyright © 2017 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.

  1. By inhibiting snail signaling and miR-23a-3p, osthole suppresses the EMT-mediated metastatic ability in prostate cancer

    PubMed Central

    Wen, Yu-Ching; Lee, Wei-Jiunn; Tan, Peng; Yang, Shun-Fa; Hsiao, Michael; Lee, Liang-Ming; Chien, Ming-Hsien

    2015-01-01

    Here we showed that Osthole, 7-methoxy-8-(3-methyl-2-butenyl) coumarin, a bioactive coumarin derivative extracted from medicinal plants, inhibited migration, invasion, epithelial to mesenchymal transition (EMT) in androgen-independent prostate cancer (AIPC) cells in vitro and metastasis of AIPC in vivo. In patients, high Snail levels were correlated with a higher histological Gleason sum and poor survival rates. Osthole inhibited the TGF-β/Akt/MAPK pathways, reduced Snail-DNA-binding activity and induced E-cadherin. We found that osthole decreased miR-23a-3p. Ectopic miR-23a-3p suppressed E-cadherin 3′ untranslated region reporter activity and E-cadherin expression, and relieved the motility suppression caused by osthole treatment. PMID:26110567

  2. By inhibiting snail signaling and miR-23a-3p, osthole suppresses the EMT-mediated metastatic ability in prostate cancer.

    PubMed

    Wen, Yu-Ching; Lee, Wei-Jiunn; Tan, Peng; Yang, Shun-Fa; Hsiao, Michael; Lee, Liang-Ming; Chien, Ming-Hsien

    2015-08-28

    Here we showed that Osthole, 7-methoxy-8-(3-methyl-2-butenyl) coumarin, a bioactive coumarin derivative extracted from medicinal plants, inhibited migration, invasion, epithelial to mesenchymal transition (EMT) in androgen-independent prostate cancer (AIPC) cells in vitro and metastasis of AIPC in vivo. In patients, high Snail levels were correlated with a higher histological Gleason sum and poor survival rates. Osthole inhibited the TGF-β/Akt/MAPK pathways, reduced Snail-DNA-binding activity and induced E-cadherin. We found that osthole decreased miR-23a-3p. Ectopic miR-23a-3p suppressed E-cadherin 3' untranslated region reporter activity and E-cadherin expression, and relieved the motility suppression caused by osthole treatment.

  3. [Shabbetay Donnolo's medical work].

    PubMed

    Tamani, G

    1999-01-01

    Shabbetay ben Abraham, called Donnolo, of Oria in Puglia (913 - post 982), is best known as a doctor. His Sefer-ha-mirqahot (the book of mixtures), often called Sefer-ha-yaqar (The precious book), containing directions for preparing medicinal roots, is based upon Greek medicine and is not only the oldest European Hebrew medical work but also the earliest medical book written in Italy (and probably in any Christian land of the West) in any language after the fall of the Roman Empire, and thus has a singular importance. After describing the preparation of the various herbs for medicinal purposes, Donnolo goes on to give prescriptions for relieving constipation, the hardening of the arteries, and rheumatic pains. Some one hundred and twenty names of medicinal plants and minerals occur in the course of this work.

  4. Preliminary Screening of Antibacterial Activity Using Crude Extracts of Hibiscus rosa sinensis

    PubMed Central

    Arullappan, Sangeetha; Zakaria, Zubaidah; Basri, Dayang Fredalina

    2009-01-01

    Hibiscus rosa sinensis, a member of the Malvaceae family, is widely cultivated in the tropics as an ornamental plant. It is often planted as a fence or hedge plant, and has several forms of flowers with varying colours. It is also used in traditional medicine to induce abortion, ease menstrual cramps, assist in childbirth and relieve headache, fever and inflammation. In this study, we evaluated the antibacterial activity of H. rosa sinesis extract using a disc diffusion method. Crude petroleum ether extract, ethyl acetate extract and methanol extract from the leaves, stems and flowers of the plant were prepared using a cold extraction technique. These extracts were tested at concentrations ranging from 4 mg/disc to 0.017 mg/disc against methicillin-resistant Staphylococcus aureus (MRSA), Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa and Klebsiella pneumonia. The petroleum ether extract from the leaves, stems and flowers and methanol extract from the leaves showed inhibition zones with diameters > 12 mm against MRSA. Overall, the petroleum ether extract from flowers at concentrations of 4 mg/disc and 2 mg/disc displayed the strongest inhibition zones of 18.6 ± 2.85 mm and 18.5 ± 0.29 mm, respectively, as compared to vancomycin (30 μg/ml), which did not differ significantly from the 18.0 ± 0.10 mm size of the vancomycin (30 μg/ml) inhibition zone (p < 0.05). In conclusion, H. rosa sinensis extract is a potential antibacterial agent for treating MRSA infection. PMID:24575183

  5. Preliminary Screening of Antibacterial Activity Using Crude Extracts of Hibiscus rosa sinensis.

    PubMed

    Arullappan, Sangeetha; Zakaria, Zubaidah; Basri, Dayang Fredalina

    2009-12-01

    Hibiscus rosa sinensis, a member of the Malvaceae family, is widely cultivated in the tropics as an ornamental plant. It is often planted as a fence or hedge plant, and has several forms of flowers with varying colours. It is also used in traditional medicine to induce abortion, ease menstrual cramps, assist in childbirth and relieve headache, fever and inflammation. In this study, we evaluated the antibacterial activity of H. rosa sinesis extract using a disc diffusion method. Crude petroleum ether extract, ethyl acetate extract and methanol extract from the leaves, stems and flowers of the plant were prepared using a cold extraction technique. These extracts were tested at concentrations ranging from 4 mg/disc to 0.017 mg/disc against methicillin-resistant Staphylococcus aureus (MRSA), Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa and Klebsiella pneumonia. The petroleum ether extract from the leaves, stems and flowers and methanol extract from the leaves showed inhibition zones with diameters > 12 mm against MRSA. Overall, the petroleum ether extract from flowers at concentrations of 4 mg/disc and 2 mg/disc displayed the strongest inhibition zones of 18.6 ± 2.85 mm and 18.5 ± 0.29 mm, respectively, as compared to vancomycin (30 μg/ml), which did not differ significantly from the 18.0 ± 0.10 mm size of the vancomycin (30 μg/ml) inhibition zone (p < 0.05). In conclusion, H. rosa sinensis extract is a potential antibacterial agent for treating MRSA infection.

  6. FAMM Flap in Reconstructing Postsurgical Nasopharyngeal Airway Stenosis

    PubMed Central

    Nangole, Ferdinand Wanjala; Khainga, Stanley Ominde

    2014-01-01

    Introduction. Postsurgical nasopharyngeal airway stenosis can be a challenge to manage. The stenosis could be as a result of any surgical procedure in the nasopharyngeal region that heals extensive scarring and fibrosis. Objective. To evaluate patients with nasopharyngeal stenosis managed with FAMM flap. Study Design. Prospective study of patients with nasopharyngeal stenosis at the Kenyatta National Hospital between 2010 and 2013 managed with FAMM flap. Materials and Methods. Patients with severe nasopharyngeal airway stenosis were reviewed and managed with FAMM flaps at the Kenyatta National Hospital. Postoperatively they were assessed for symptomatic improvement in respiratory distress, patency of the nasopharyngeal airway, and donor site morbidity. Results. A total of 8 patients were managed by the authors in a duration of 4 years with nasopharyngeal stenosis. Five patients were managed with unilateral FAMM flaps in a two-staged surgical procedure. Four patients had complete relieve of the airway obstruction with a patent airway created. One patient had a patent airway created though with only mild improvement in airway obstruction. Conclusion. FAMM flap provides an alternative in the management of postsurgical severe nasopharyngeal stenosis. It is a reliable flap that is easy to raise and could provide adequate epithelium for the stenosed pharynx. PMID:25328699

  7. Photoexcitation cascade and quantum-relativistic jet formation in graphene

    NASA Astrophysics Data System (ADS)

    Lewandowski, Cyprian; Levitov, Leonid

    Interactions between ultra-relativistic particles can lead to striking behavior in which a high-energy particle creates showers of softer particles characterized by a collimated angular distribution aligned with the particle velocity. These showers, known as jets, are a generic phenomenon relevant for all quantum cascades of linearly dispersing particles. This talk will discuss jets formed upon photoexcitation in graphene, which due to its linear dispersion provides an appealing medium for exploring quantum-relativistic phenomena. We will study the cascade generated by carrier-carrier collisions in photon absorption, wherein a single photon creates an electron-hole (e-h) excitation that decays producing multiple near-collinear secondary e-h excitations. We will argue that the cascade can occur through an off-shell mechanism such that all the particles and holes involved reside outside the energy-momentum dispersion manifold, relieving the bottleneck arising in the on-shell process due to energy and momentum conservation. The characteristics of the jets such as the angular and energy distribution of the particles will be discussed. Photogenerated jets provide an interesting setting to investigate the carrier-carrier collision processes in graphene and other Dirac materials. We acknowledge support of the Center for Integrated Quantum Materials (CIQM) under NSF award DMR-1231319.

  8. Origin, diagnostics, and mitigation of a salt dissolution sinkhole at the US Strategic Petroleum Reserve storage site, Weeks Island, Louisiana

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Neal, J.T.; Myers, R.E.

    1995-01-27

    A sinkhole was first observed in May 1992 over the edge of the two-level former salt mine that was converted for oil storage by the US Strategic Petroleum Reserve (SPR). Diagnostic studies that included geophysical, geochemical, drilling, and hydrological methods suggest a direct connection exists between the surface collapse area and the underground mine as shown by correlative measurements of sediment slump rates and brine influx into the mine. The dissolution of salt below the sinkhole that initiated the leak into the mine was likely caused by several confluent geologic processes, and exacerbated by mining-induced stresses that created fractures whichmore » served as hydrologic flowpaths. Modeling studies of mine stresses show that years may be required before tensional cracking begins to occur, but once begun can continue to develop, and relieve the stress in that specific regime. The crack regime creates the avenue for incursion of groundwater, very slowly initially, but gradually enlarging as undersaturated groundwater dissolves salt on the sides of the crack. Mitigation measures include increasing the mine pressurization, slowing the dissolution by injecting brine into the sinkhole throat, and freeze grouting to restrict hydrologic flowpaths.« less

  9. Only adding stationary storage to vaccine supply chains may create and worsen transport bottlenecks.

    PubMed

    Haidari, Leila A; Connor, Diana L; Wateska, Angela R; Brown, Shawn T; Mueller, Leslie E; Norman, Bryan A; Schmitz, Michelle M; Paul, Proma; Rajgopal, Jayant; Welling, Joel S; Leonard, Jim; Claypool, Erin G; Weng, Yu-Ting; Chen, Sheng-I; Lee, Bruce Y

    2013-01-01

    Although vaccine supply chains in many countries require additional stationary storage and transport capacity to meet current and future needs, international donors tend to donate stationary storage devices far more often than transport equipment. To investigate the impact of only adding stationary storage equipment on the capacity requirements of transport devices and vehicles, we used HERMES (Highly Extensible Resource for Modeling Supply Chains) to construct a discrete event simulation model of the Niger vaccine supply chain. We measured the transport capacity requirement for each mode of transport used in the Niger vaccine cold chain, both before and after adding cold rooms and refrigerators to relieve all stationary storage constraints in the system. With the addition of necessary stationary storage, the average transport capacity requirement increased from 88% to 144% for cold trucks, from 101% to 197% for pickup trucks, and from 366% to 420% for vaccine carriers. Therefore, adding stationary storage alone may worsen or create new transport bottlenecks as more vaccines flow through the system, preventing many vaccines from reaching their target populations. Dynamic modeling can reveal such relationships between stationary storage capacity and transport constraints.

  10. Only Adding Stationary Storage to Vaccine Supply Chains May Create and Worsen Transport Bottlenecks

    PubMed Central

    Haidari, Leila A.; Connor, Diana L.; Wateska, Angela R.; Brown, Shawn T.; Mueller, Leslie E.; Norman, Bryan A.; Schmitz, Michelle M.; Paul, Proma; Rajgopal, Jayant; Welling, Joel S.; Leonard, Jim; Claypool, Erin G.; Weng, Yu-Ting; Chen, Sheng-I; Lee, Bruce Y.

    2015-01-01

    Although vaccine supply chains in many countries require additional stationary storage and transport capacity to meet current and future needs, international donors tend to donate stationary storage devices far more often than transport equipment. To investigate the impact of only adding stationary storage equipment on the capacity requirements of transport devices and vehicles, we used HERMES (Highly Extensible Resource for Modeling Supply Chains) to construct a discrete event simulation model of the Niger vaccine supply chain. We measured the transport capacity requirement for each mode of transport used in the Niger vaccine cold chain, both before and after adding cold rooms and refrigerators to relieve all stationary storage constraints in the system. With the addition of necessary stationary storage, the average transport capacity requirement increased from 88% to 144% for cold trucks, from 101% to 197% for pickup trucks, and from 366% to 420% for vaccine carriers. Therefore, adding stationary storage alone may worsen or create new transport bottlenecks as more vaccines flow through the system, preventing many vaccines from reaching their target populations. Dynamic modeling can reveal such relationships between stationary storage capacity and transport constraints. PMID:23903398

  11. Brazil's conditional cash transfer program associated with declines in infant mortality rates.

    PubMed

    Shei, Amie

    2013-07-01

    Conditional cash transfer programs are innovative social safety-net programs that aim to relieve poverty. They provide a regular source of income to poor families and are "conditional" in that they require poor families to invest in the health and education of their children through greater use of educational and preventive health services. Brazil's Bolsa Família conditional cash transfer program, created in 2003, is the world's largest program of its kind. During the first five years of the program, it was associated with a significant 9.3 percent reduction in overall infant mortality rates, with greater declines in postneonatal mortality rates than in mortality rates at an earlier age and in municipalities with many users of Brazil's Family Health Program than in those with lower use rates. There were also larger effects in municipalities with higher infant mortality rates at baseline. Programs like Bolsa Família can improve child health and reduce long-standing health inequalities. Policy makers should review the adequacy of basic health services to ensure that the services can respond to the increased demand created by such programs. Programs should also target vulnerable groups at greatest risk and include careful monitoring and evaluation.

  12. Measuring whole-plant transpiration gravimetrically: a scalable automated system built from components

    Treesearch

    Damian Cirelli; Victor J. Lieffers; Melvin T. Tyree

    2012-01-01

    Measuring whole-plant transpiration is highly relevant considering the increasing interest in understanding and improving plant water use at the whole-plant level. We present an original software package (Amalthea) and a design to create a system for measuring transpiration using laboratory balances based on the readily available commodity hardware. The system is...

  13. Site preparation + 1 year: effect on plant cover and soil properties

    Treesearch

    Raymond D Ratliff; Renee G. Denton

    1991-01-01

    Preparing for planting conifer seedlings reduces competition for site resources but creates poor range conditions. bare soil, low plant cover, adn little forage do not support forest grazing programs. At Boyd Hill on the Modoc National Forest, in California, several regeneration sites were prepared in 1988. Early in 1989 they were planted with ponderosa pine (...

  14. Developing native plant nurseries in emerging market areas

    Treesearch

    Elliott Duemler

    2012-01-01

    The importance of developing a market for quality native plant materials in a region prior to the establishment of a nursery is crucial to ensure its success. Certain tactics can be applied to help develop a demand for native plant materials in a region. Using these tactics will help create a new market for native plant materials.

  15. Generic HTML Form Processor: A versatile PHP script to save web-collected data into a MySQL database.

    PubMed

    Göritz, Anja S; Birnbaum, Michael H

    2005-11-01

    The customizable PHP script Generic HTML Form Processor is intended to assist researchers and students in quickly setting up surveys and experiments that can be administered via the Web. This script relieves researchers from the burdens of writing new CGI scripts and building databases for each Web study. Generic HTML Form Processor processes any syntactically correct HTML forminput and saves it into a dynamically created open-source database. We describe five modes for usage of the script that allow increasing functionality but require increasing levels of knowledge of PHP and Web servers: The first two modes require no previous knowledge, and the fifth requires PHP programming expertise. Use of Generic HTML Form Processor is free for academic purposes, and its Web address is www.goeritz.net/brmic.

  16. Embedded Librarian as Research Team Member.

    PubMed

    Brahmi, Frances A; Kaplan, F Thomas D

    2017-03-01

    Adding a librarian to an upper extremity surgical and therapy practice has many advantages (educational, research, remaining on the cutting edge of technology). As an embedded team member, the librarian at the Indiana Hand to Shoulder Center prepares literature reviews, creates Google Scholar Alerts for individual clinicians, and introduces developing technologies such as 3-dimensional printers, Smartphone Apps, and online access to nontraditional resources. With the librarian relieving clinicians of these responsibilities, surgeons can devote more time to clinical and research activities. Private practices unable to support their own librarian could share access to a librarian via Skype, Face Time, and video conferencing. Another small practice alternative is contracting services from a local medical school library that designates a librarian as its liaison. Copyright © 2017 American Society for Surgery of the Hand. Published by Elsevier Inc. All rights reserved.

  17. Evaluating selection and efficacy of pressure-relieving equipment.

    PubMed

    Chaloner, Donna; Stevens, Jenny

    2003-06-01

    The drive towards evidence-based practice has highlighted the lack of randomized controlled trials that compare interventions such as pressure-relieving medical devices. This may influence practitioners, particularly purchasing practitioners, to consider other types of evidence when appraising literature to determine clinical practice and support recommendations and local guidelines. This article will illustrate the development of an audit tool used to evaluate nurses' knowledge and skills in patient assessment, selection and installation of appropriate pressure-relieving equipment. The tool also assists in assessing clinical effectiveness and user satisfaction of equipment. This article focuses on a small audit of the Karomed Ltd Transair 1500 (also known as the 3-Comm) mattress replacement system.

  18. A case of gait disturbance caused by low-dose gabapentin

    PubMed Central

    Kanao-Kanda, Megumi; Kanda, Hirotsugu; Takahata, Osamu; Kunisawa, Takayuki

    2016-01-01

    Gabapentin, an anticonvulsant agent, is now often used for the treatment of neuropathic pain all over the world. It is unclear whether the combined use of gabapentin, sodium valproate, and flunitrazepam results in enhancement of the side effect, a gait disturbance. A 60-year-old man was taking oral sodium valproate for symptomatic epilepsy after a brain contusion and flunitrazepam to relieve insomnia. Oral gabapentin therapy was started for suspected neuropathic pain. Although the initial dose of oral gabapentin (200 mg) relieved the pain, the lower extremities became weak, resulting in a gait disturbance. The therapy was restarted with a halved dose, and this resolved the gait disturbance and relieved the pain. PMID:27354808

  19. Novel technique for relieving anastomotic tension using halo-vest immobilization after tracheal sleeve resection.

    PubMed

    Imai, Kazuhiro; Minamiya, Yoshihiro; Saito, Hajime; Miyakoshi, Naohisa; Hongo, Michio; Kasukawa, Yuji; Ishikawa, Yoshinori; Motoyama, Satoru; Sato, Yusuke; Shimada, Yoichi; Ogawa, Jun-ichi

    2013-07-01

    We describe a novel technique of using halo-vest-enforced immobilization to relieve anastomotic tension after tracheal sleeve resection. Immediately after the tracheal sleeve resection, four halo titanium pins were inserted in the skulls of the patients to secure the halo-vest. All patients fitted with halo-vests were able to eat and drink and their clinical course was good. Bronchoscopy confirmed the absence of anastomotic leaks and stenoses, and there were no complications associated with the halo-vest. We believe that ensuring neck flexion using a halo-vest after tracheal sleeve resection is an excellent way of relieving anastomotic tension that would predispose the wound to dehiscence.

  20. Pelvic belt effects on sacroiliac joint ligaments: a computational approach to understand therapeutic effects of pelvic belts.

    PubMed

    Sichting, Freddy; Rossol, Jerome; Soisson, Odette; Klima, Stefan; Milani, Thomas; Hammer, Niels

    2014-01-01

    The sacroiliac joint is a widely described source of low back pain. Therapeutic approaches to relieve pain include the application of pelvic belts. However, the effects of pelvic belts on sacroiliac joint ligaments as potential pain generators are mostly unknown. The aim of our study was to analyze the influence of pelvic belts on ligament load by means of a computer model. Experimental computer study using a finite element method. A computer model of the human pelvis was created, comprising bones, ligaments, and cartilage. Detailed geometries, material properties of ligaments, and in-vivo pressure distribution patterns of a pelvic belt were implemented. The effects of pelvic belts on ligament strain were computed in the double-leg stance. Pelvic belts increase sacroiliac joint motion around the sagittal axis but decrease motion around the transverse axis. With pelvic belt application, most of the strained sacroiliac joint ligaments were relieved, especially the sacrospinous, sacrotuberous, and the interosseous sacroiliac ligaments. Sacroiliac joint motion and ligament strains were minute. These results agree with validation data from other studies. Assigning homogenous and linear material properties and excluding muscle forces are clear simplifications of the complex reality. Pelvic belts alter sacroiliac joint motion and provide partial relief of ligament strain that is subjectively marked, although minimal in absolute terms. These findings confirm theories that besides being mechanical stabilizers, the sacroiliac joint ligaments are likely involved in neuromuscular feedback mechanisms. The results from our computer model help with unraveling the therapeutic mechanisms of pelvic belts.

  1. 49 CFR 192.201 - Required capacity of pressure relieving and limiting stations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Design of Pipeline Components § 192.201 Required capacity of pressure relieving and limiting stations. (a) Each pressure relief station or pressure limiting station or group of those stations installed to... part of the pipeline or distribution system in excess of those for which it was designed, or against...

  2. 21 CFR 349.75 - Labeling of ophthalmic vasoconstrictor drug products.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... “redness reliever” or “vasoconstrictor (redness reliever)” (select one of the following: “eye” or... the heading “Indications,” the following phrase: “Relieves redness of the eye due to minor eye....18: (1) “If you experience eye pain, changes in vision, continued redness or irritation of the eye...

  3. 21 CFR 349.75 - Labeling of ophthalmic vasoconstrictor drug products.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... “redness reliever” or “vasoconstrictor (redness reliever)” (select one of the following: “eye” or... the heading “Indications,” the following phrase: “Relieves redness of the eye due to minor eye....18: (1) “If you experience eye pain, changes in vision, continued redness or irritation of the eye...

  4. Directing traffic on DNA-How transcription factors relieve or induce transcriptional interference.

    PubMed

    Hao, Nan; Palmer, Adam C; Dodd, Ian B; Shearwin, Keith E

    2017-03-15

    Transcriptional interference (TI) is increasingly recognized as a widespread mechanism of gene control, particularly given the pervasive nature of transcription, both sense and antisense, across all kingdoms of life. Here, we discuss how transcription factor binding kinetics strongly influence the ability of a transcription factor to relieve or induce TI.

  5. 21 CFR 868.5115 - Device to relieve acute upper airway obstruction.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 8 2012-04-01 2012-04-01 false Device to relieve acute upper airway obstruction. 868.5115 Section 868.5115 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES ANESTHESIOLOGY DEVICES Therapeutic Devices § 868.5115 Device to...

  6. 21 CFR 868.5115 - Device to relieve acute upper airway obstruction.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Device to relieve acute upper airway obstruction. 868.5115 Section 868.5115 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES ANESTHESIOLOGY DEVICES Therapeutic Devices § 868.5115 Device to...

  7. 21 CFR 868.5115 - Device to relieve acute upper airway obstruction.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 8 2013-04-01 2013-04-01 false Device to relieve acute upper airway obstruction. 868.5115 Section 868.5115 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES ANESTHESIOLOGY DEVICES Therapeutic Devices § 868.5115 Device to...

  8. 29 CFR 790.4 - Liability of employer; effect of contract, custom, or practice.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ..., this section relieves the employer from certain liabilities or punishments to which he might otherwise... by such employee is relieved from liability or punishment therefor if, and only if, such activities... an employer of liability or punishment only with respect to activities of the kind described, which...

  9. 29 CFR 790.4 - Liability of employer; effect of contract, custom, or practice.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ..., this section relieves the employer from certain liabilities or punishments to which he might otherwise... by such employee is relieved from liability or punishment therefor if, and only if, such activities... an employer of liability or punishment only with respect to activities of the kind described, which...

  10. 29 CFR 790.4 - Liability of employer; effect of contract, custom, or practice.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ..., this section relieves the employer from certain liabilities or punishments to which he might otherwise... by such employee is relieved from liability or punishment therefor if, and only if, such activities... an employer of liability or punishment only with respect to activities of the kind described, which...

  11. 29 CFR 790.4 - Liability of employer; effect of contract, custom, or practice.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ..., this section relieves the employer from certain liabilities or punishments to which he might otherwise... by such employee is relieved from liability or punishment therefor if, and only if, such activities... an employer of liability or punishment only with respect to activities of the kind described, which...

  12. The relieving effects of shelter modes on physiological stress of traffic police in summer

    NASA Astrophysics Data System (ADS)

    Zheng, G. Z.; Wang, Y. J.; Bu, W. T.; Lu, Y. Z.; Li, Ke; Li, Z. H.

    2018-03-01

    In summer, high temperature and strong sun radiation last for a long time. However, traffic police still stick to their positions to ensure normal traffic order. Therefore, the health and safety of traffic police are challenged by the high temperature weather. To protect the safety of the traffic police in the outdoor high temperature environment, some shelter modes, such as sun hat and sun umbrella are selected for duty traffic police. The relieving effects on the physiological stress of the shelter modes are analyzed by comparison of the physiological parameters in these shelter modes. The results show that sun umbrella has a good effect on relieving physiological stress. And sun hat has no effect on relieving physiological stress, although it avoids the direct sunlight on the face. However, it causes the increase of the thermal sensation. This study can provide important methods for health protecting of traffic police in the outdoor high temperature environment. It also provides a theoretical support for the revision of the outdoor high temperature labour protection standard.

  13. Non-Prescribed Use of Pain Relievers among Adolescents in the United States

    PubMed Central

    Wu, Li-Tzy; Pilowsky, Daniel J.; Patkar, Ashwin A.

    2008-01-01

    Background We examined gender-specific prevalences, patterns, and correlates of non-prescribed use of pain relievers—mainly opioids—in a representative sample of American adolescents (N = 18,678). Methods Data were drawn from the public use data file of the 2005 U.S. National Survey on Drug Use and Health, a survey of non-institutionalized American household residents. The patterns of non-prescribed use of prescription pain relievers were examined, and logistic regression procedures were conducted to identify correlates of non-prescribed use. Results Approximately one in 10 adolescents aged 12−17 years reported non-prescribed use of pain relievers in their lifetime (9.3% in males and 10.3% in females). The mean age of first non-prescribed use was 13.3 years, which was similar to the mean age of first use of alcohol and marijuana but older than the age of first inhalant use. Among all non-prescribed users, 52% reported having used hydrocodone products (Vicodin, Lortab, Lorcet, and Lorcet Plus, and hydrocodone), 50% had used propoxyphene (Darvocet or Darvon) or codeine (Tylenol with codeine), and 24% had used oxycodone products (OxyContin, Percocet, Percodan, and Tylox). Approximately one quarter (26%) of all non-prescribed users had never used other non-prescribed or illicit drugs. There were gender variations in correlates of non-prescribed use. Conclusions Use of non-prescribed pain relievers occurs early in adolescence. Research is needed to understand whether early use of non-prescribed pain relievers is related to later drug use. PMID:18054444

  14. Korean Emotional Laborers' Job Stressors and Relievers: Focus on Work Conditions and Emotional Labor Properties

    PubMed Central

    Lee, Garam

    2015-01-01

    Background The present study aims to investigate job stressors and stress relievers for Korean emotional laborers, specifically focusing on the effects of work conditions and emotional labor properties. Emotional laborers are asked to hide or distort their real emotions in their interaction with clients. They are exposed to high levels of stress in the emotional labor process, which leads to serious mental health risks including burnout, depression, and even suicide impulse. Exploring job stressors and relieving factors would be the first step in seeking alternatives to protect emotional laborers from those mental health risks. Methods Using the third wave data of Korean Working Conditions Survey, logistic regression analysis was conducted for two purposes: to examine the relations of emotional labor and stress, and to find out job stressors and relievers for emotional laborers. Results The chances of stress arousal are 3.5 times higher for emotional laborers; emotional laborers experience double risk-burden for stress arousal. In addition to general job stressors, emotional laborers need to bear burdens related to emotional labor properties. The effect of social support at the workplace is not significant for stress relief, unlike common assumptions, whereas subjective satisfaction (wage satisfaction and work-life balance) is proven to have relieving effects on emotional laborers' job stress. Conclusion From the results, the importance of a balanced understanding of emotional labor for establishing effective policies for emotional laborer protection is stressed. PMID:26929847

  15. Variations in Care Quality Outcomes of Dying People: Latent Class Analysis of an Adult National Register Population.

    PubMed

    Öhlén, Joakim; Russell, Lara; Håkanson, Cecilia; Alvariza, Anette; Fürst, Carl Johan; Årestedt, Kristofer; Sawatzky, Richard

    2017-01-01

    Symptom relief is a key goal of palliative care. There is a need to consider complexities in symptom relief patterns for groups of people to understand and evaluate symptom relief as an indicator of quality of care at end of life. The aims of this study were to distinguish classes of patients who have different symptom relief patterns during the last week of life and to identify predictors of these classes in an adult register population. In a cross-sectional retrospective design, data were used from 87,026 decedents with expected deaths registered in the Swedish Register of Palliative Care in 2011 and 2012. Study variables were structured into patient characteristics, and processes and outcomes of quality of care. A latent class analysis was used to identify symptom relief patterns. Multivariate multinomial regression analyses were used to identify predictors of class membership. Five latent classes were generated: "relieved pain," "relieved pain and rattles," "relieved pain and anxiety," "partly relieved shortness of breath, rattles and anxiety," and "partly relieved pain, anxiety and confusion." Important predictors of class membership were age, sex, cause of death, and having someone present at death, individual prescriptions as needed (PRN) and expert consultations. Interindividual variability and complexity in symptom relief patterns may inform quality of care and its evaluation for dying people across care settings. Copyright © 2016 American Academy of Hospice and Palliative Medicine. Published by Elsevier Inc. All rights reserved.

  16. Evidence for cognitive-behavioral strategies improving dyspnea and related distress in COPD.

    PubMed

    Norweg, Anna; Collins, Eileen G

    2013-01-01

    Dyspnea is a complex, prevalent, and distressing symptom of chronic obstructive pulmonary disease (COPD) associated with decreased quality of life, significant disability, and increased mortality. It is a major reason for referral to pulmonary rehabilitation. We reviewed 23 COPD studies to examine the evidence for the effectiveness of cognitive-behavioral strategies for relieving dyspnea in COPD. Preliminary evidence from randomized controlled trials exists to support cognitive- behavioral strategies, used with or without exercise, for relieving sensory and affective components of dyspnea in COPD. Small to moderate treatment effects for relieving dyspnea were noted for psychotherapy (effect size [ES] = 0.08-0.25 for intensity; 0.26-0.65 for mastery) and distractive auditory stimuli (ES = 0.08-0.33 for intensity; 0.09 to -0.61 for functional burden). Small to large dyspnea improvements resulted from yoga (ES = 0.2-1.21 for intensity; 0.67 for distress; 0.07 for mastery; and -8.37 for functional burden); dyspnea self-management education with exercise (ES = -0.14 to -1.15 for intensity; -0.62 to -0.69 for distress; 1.04 for mastery; 0.14-0.35 for self-efficacy); and slow-breathing exercises (ES = -0.34 to -0.83 for intensity; -0.61 to -0.80 for distress; and 0.62 for self-efficacy). Cognitive-behavioral interventions may relieve dyspnea in COPD by (1) decreasing sympathetic nerve activity, dynamic hyperinflation, and comorbid anxiety, and (2) promoting arterial oxygen saturation, myelinated vagus nerve activity, a greater exercise training effect, and neuroplasticity. While evidence is increasing, additional randomized controlled trials are needed to evaluate the effectiveness of psychosocial and self-management interventions in relieving dyspnea, in order to make them more available to patients and to endorse them in official COPD, dyspnea, and pulmonary rehabilitation practice guidelines. By relieving dyspnea and related anxiety, such interventions may promote adherence to exercise programs and adaptive lifestyle change.

  17. Engineering Mycorrhizal Symbioses to Alter Plant Metabolism and Improve Crop Health

    PubMed Central

    French, Katherine E.

    2017-01-01

    Creating sustainable bioeconomies for the 21st century relies on optimizing the use of biological resources to improve agricultural productivity and create new products. Arbuscular mycorrhizae (phylum Glomeromycota) form symbiotic relationships with over 80% of vascular plants. In return for carbon, these fungi improve plant health and tolerance to environmental stress. This symbiosis is over 400 million years old and there are currently over 200 known arbuscular mycorrhizae, with dozens of new species described annually. Metagenomic sequencing of native soil communities, from species-rich meadows to mangroves, suggests biologically diverse habitats support a variety of mycorrhizal species with potential agricultural, medical, and biotechnological applications. This review looks at the effect of mycorrhizae on plant metabolism and how we can harness this symbiosis to improve crop health. I will first describe the mechanisms that underlie this symbiosis and what physiological, metabolic, and environmental factors trigger these plant-fungal relationships. These include mycorrhizal manipulation of host genetic expression, host mitochondrial and plastid proliferation, and increased production of terpenoids and jasmonic acid by the host plant. I will then discuss the effects of mycorrhizae on plant root and foliar secondary metabolism. I subsequently outline how mycorrhizae induce three key benefits in crops: defense against pathogen and herbivore attack, drought resistance, and heavy metal tolerance. I conclude with an overview of current efforts to harness mycorrhizal diversity to improve crop health through customized inoculum. I argue future research should embrace synthetic biology to create mycorrhizal chasses with improved symbiotic abilities and potentially novel functions to improve plant health. As the effects of climate change and anthropogenic disturbance increase, the global diversity of arbuscular mycorrhizal fungi should be monitored and protected to ensure this important agricultural and biotechnological resource for the future. PMID:28785256

  18. Engineering Mycorrhizal Symbioses to Alter Plant Metabolism and Improve Crop Health.

    PubMed

    French, Katherine E

    2017-01-01

    Creating sustainable bioeconomies for the 21st century relies on optimizing the use of biological resources to improve agricultural productivity and create new products. Arbuscular mycorrhizae (phylum Glomeromycota) form symbiotic relationships with over 80% of vascular plants. In return for carbon, these fungi improve plant health and tolerance to environmental stress. This symbiosis is over 400 million years old and there are currently over 200 known arbuscular mycorrhizae, with dozens of new species described annually. Metagenomic sequencing of native soil communities, from species-rich meadows to mangroves, suggests biologically diverse habitats support a variety of mycorrhizal species with potential agricultural, medical, and biotechnological applications. This review looks at the effect of mycorrhizae on plant metabolism and how we can harness this symbiosis to improve crop health. I will first describe the mechanisms that underlie this symbiosis and what physiological, metabolic, and environmental factors trigger these plant-fungal relationships. These include mycorrhizal manipulation of host genetic expression, host mitochondrial and plastid proliferation, and increased production of terpenoids and jasmonic acid by the host plant. I will then discuss the effects of mycorrhizae on plant root and foliar secondary metabolism. I subsequently outline how mycorrhizae induce three key benefits in crops: defense against pathogen and herbivore attack, drought resistance, and heavy metal tolerance. I conclude with an overview of current efforts to harness mycorrhizal diversity to improve crop health through customized inoculum. I argue future research should embrace synthetic biology to create mycorrhizal chasses with improved symbiotic abilities and potentially novel functions to improve plant health. As the effects of climate change and anthropogenic disturbance increase, the global diversity of arbuscular mycorrhizal fungi should be monitored and protected to ensure this important agricultural and biotechnological resource for the future.

  19. A Genetic Approach to the Identification of Plant Genes Involved in Viral Movement

    DTIC Science & Technology

    1999-09-30

    Arabidopsis.. We plan to create two transgenic plant lines of Arabidopsis, one that expresses the firefly luciferase (Luc) gene, and one that... transgenic plant lines that express Luc or CD upon infection with RCNMV. Phenotypically these lines will either be luminescent (Luc) or sensitive to 5

  20. Native plant development and deployment [Section VII

    Treesearch

    Jessica Wright; Kas Dumroese; Amy Symstad; Theresa Pitts-Singer; Jim Cane; Gary Krupnick; Peggy Olwell; Byron Love; Elizabeth Sellers; John Englert; Troy Wood

    2015-01-01

    Native plant materials are needed to create, enhance, or restore pollinator habitat. They provide critical foraging and breeding areas for wild and managed pollinator species, including transnational migratory species such as hummingbirds and monarch butterflies. Although many pollinators and plants are generalists, some have limited, obligate relationships (i.e., one...

  1. Invertebrates and Plants

    Treesearch

    Wendell R. Haag; Robert J. Distefano; Siobhan Fennessy; Brett D. Marshall

    2013-01-01

    Invertebrates and plants are among the most ubiquitous and abundant macroscopic organisms in aquatic ecosystems; they dominate most habitats in both diversity and biomass and play central roles in aquatic food webs. Plants regulate and create habitats for a wide array of organisms (Cooke et al. 2005). Snail grazing and bivalve filtering profoundly alter habitats and...

  2. Precision genome engineering and agriculture: opportunities and regulatory challenges.

    PubMed

    Voytas, Daniel F; Gao, Caixia

    2014-06-01

    Plant agriculture is poised at a technological inflection point. Recent advances in genome engineering make it possible to precisely alter DNA sequences in living cells, providing unprecedented control over a plant's genetic material. Potential future crops derived through genome engineering include those that better withstand pests, that have enhanced nutritional value, and that are able to grow on marginal lands. In many instances, crops with such traits will be created by altering only a few nucleotides among the billions that comprise plant genomes. As such, and with the appropriate regulatory structures in place, crops created through genome engineering might prove to be more acceptable to the public than plants that carry foreign DNA in their genomes. Public perception and the performance of the engineered crop varieties will determine the extent to which this powerful technology contributes towards securing the world's food supply.

  3. 32 CFR 733.3 - Information and policy on support of dependents.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... children. The natural parents of an adopted child are relieved of the obligation to support the child as.... (iii) If custody of children of the marriage is divided between the two parents: interim support shall... given no force or effect. (vii) The natural parents of an adopted child are relieved of the obligation...

  4. 32 CFR 733.3 - Information and policy on support of dependents.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... children. The natural parents of an adopted child are relieved of the obligation to support the child as.... (iii) If custody of children of the marriage is divided between the two parents: interim support shall... given no force or effect. (vii) The natural parents of an adopted child are relieved of the obligation...

  5. 21 CFR 868.5115 - Device to relieve acute upper airway obstruction.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... the event of choking on a foreign body, can be applied to the abdomen and pushed upward to generate... 21 Food and Drugs 8 2014-04-01 2014-04-01 false Device to relieve acute upper airway obstruction. 868.5115 Section 868.5115 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN...

  6. 21 CFR 868.5115 - Device to relieve acute upper airway obstruction.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Device to relieve acute upper airway obstruction. 868.5115 Section 868.5115 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN... the event of choking on a foreign body, can be applied to the abdomen and pushed upward to generate...

  7. 49 CFR 390.23 - Relief from regulations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... the time the driver is relieved of all duty if the employing motor carrier does not operate every day... the time the driver is relieved of all duty if the employing motor carrier operates every day in the... relief, or 30 days from the date of the initial declaration of the emergency or the exemption from the...

  8. The Impact of Biblio Group Counseling Supported with the Story of "The Little Prince" upon Mindfulness

    ERIC Educational Resources Information Center

    Ilbay, Azmi Bayram

    2016-01-01

    Using books for healing psychological health is becoming popular day by day. In this process bibliotherapy brings forward suggestions of psychological insight, relieving by identification, relieving from suppressed feelings by discharging and reflecting emotions. The aim of this research is to analyse the effect of biblio group counseling…

  9. Volar denervation and osteophyte resection to relieve volar CMC joint pain.

    PubMed

    Dellon, A Lee

    2017-01-01

    At mean 125.6 months, pain was reduced from mean of 8.7 to 0.67, p  < .001. Each of three patients, two of whom were musicians, returned to full professional ability. It is concluded that volar CMC joint denervation is a useful procedure, preserving joint function and relieving pain long-term.

  10. The phyllophagous of woody plants of genus Ulmus in protective plantings of arid zone

    NASA Astrophysics Data System (ADS)

    Belitskaya, M. N.; Gribust, I. R.; Nefed'eva, E. E.; Filimonova, O. S.; Golovanova, M. A.

    2018-01-01

    Creating of long-lasting, normally developing plantings on the urbanized territories in the arid zones is difficult. The main tree species are elm (Fam. Ulmaceae - more than 70% of tree composition). They have a high drought and salt tolerance, rapid growth. They are widely used in the creation of artificial forest plantings in steppes and deserts. The main part of the plantations was created in the 50-60 years of 20th century. Today the aging of plants is observing. Trees of this age lose their physiological and decorative potential as well as resistance to pests under intensive anthropogenic impact. At the forest pathology research about 90 % of the plants of elm species of plantings of various types and categories were identified to be in poor condition. Leaf-eating pests play an active role in the deterioration of their sanitary state. Xanthogaleruca luteola (Müller, 1766), Cladius ulmi (Linnaeus, 1758), and Aproceros leucopoda (Takeuchi, 1939) have a special harmfulness as well as the regularity of the local centers among the mass phyllophagous of plants of the family. The last two species were discovered in artificial plantations for the first time. The destructive effect of those pests on certain types of elm plants is uneven.

  11. Impact of vegetation on land-atmosphere coupling strength and its implication for desertification mitigation over East Asia

    NASA Astrophysics Data System (ADS)

    Myoung, Boksoon; Choi, Yong-Sang; Choi, Suk-Jin; Park, Seon Ki

    2012-06-01

    Desertification of the East Asian drylands and the consequent dust transport have been serious concerns for adjacent Asian countries as well as the western United States. Tree planting has been considered one applicable strategy to mitigate the desertification. However, the desired effect of the tree planting would not be brought to fruition unless the newly planted trees change the coupling characteristics between the land and the atmosphere. Based on this perception, we attempt to clarify the effects of vegetation on the coupling strength between the atmosphere and land surface, and we suggest the most efficient areas of tree planting for desertification mitigation in East Asia. Using regional vegetation-atmosphere coupled model simulations, coupling strength with and without vegetation was computed and compared with each other. An increased vegetation fraction reduces the coupling strength in June, July, and August (JJA), primarily due to decreased evapotranspiration variability. This effect is pronounced over the Manchurian Plains and the highly populated areas of Beijing and Tianjin. The reduced coupling strength tends to weaken feedback between soil moisture and precipitation as a maintenance mechanism of warm season droughts in the midlatitudes and subsequently decrease the probability of droughts, a finding that is reflected in the enhanced JJA mean soil moisture. However, some drylands like the eastern edges of the Gobi desert present marginal or even opposite changes in coupling strength, meaning a limited effect of vegetation on relieving droughts. Therefore, given limited financial and human resources, acupuncture-like afforestation, i.e., concentrated tree planting in a particular region where the coupling strength can be substantially reduced by vegetation, is an effective strategy to secure long-standing desertification mitigation.

  12. A Gibberellin-Mediated DELLA-NAC Signaling Cascade Regulates Cellulose Synthesis in Rice[OPEN

    PubMed Central

    Huang, Debao; Wang, Shaogan; Zhang, Baocai; Shang-Guan, Keke; Shi, Yanyun; Zhang, Dongmei; Liu, Xiangling; Wu, Kun; Xu, Zuopeng; Fu, Xiangdong; Zhou, Yihua

    2015-01-01

    Cellulose, which can be converted into numerous industrial products, has important impacts on the global economy. It has long been known that cellulose synthesis in plants is tightly regulated by various phytohormones. However, the underlying mechanism of cellulose synthesis regulation remains elusive. Here, we show that in rice (Oryza sativa), gibberellin (GA) signals promote cellulose synthesis by relieving the interaction between SLENDER RICE1 (SLR1), a DELLA repressor of GA signaling, and NACs, the top-layer transcription factors for secondary wall formation. Mutations in GA-related genes and physiological treatments altered the transcription of CELLULOSE SYNTHASE genes (CESAs) and the cellulose level. Multiple experiments demonstrated that transcription factors NAC29/31 and MYB61 are CESA regulators in rice; NAC29/31 directly regulates MYB61, which in turn activates CESA expression. This hierarchical regulation pathway is blocked by SLR1-NAC29/31 interactions. Based on the results of anatomical analysis and GA content examination in developing rice internodes, this signaling cascade was found to be modulated by varied endogenous GA levels and to be required for internode development. Genetic and gene expression analyses were further performed in Arabidopsis thaliana GA-related mutants. Altogether, our findings reveal a conserved mechanism by which GA regulates secondary wall cellulose synthesis in land plants and provide a strategy for manipulating cellulose production and plant growth. PMID:26002868

  13. The role of wildfire in the establishment and range expansion of nonnative plant species into natural areas: A review of current literature

    Treesearch

    Mara Johnson; Lisa J. Rew; Bruce D. Maxwell; Steve Sutherland

    2006-01-01

    Nonnative invasive plants are one of the greatest threats to natural ecosystems worldwide (Vitousek et al. 1996). In fact, their spread has been described as "a raging biological wildfire" (Dewey et al. 1995). Disturbances tend to create conditions that are favorable for germination and establishment of plant species. Nonnative plant species are often...

  14. Mysterious Mycorrhizae? A Field Trip & Classroom Experiment to Demystify the Symbioses Formed between Plants & Fungi

    ERIC Educational Resources Information Center

    Johnson, Nancy C.; Chaudhary, V. Bala; Hoeksema, Jason D.; Moore, John C.; Pringle, Anne; Umbanhowar, James A.; Wilson, Gail W. T.

    2009-01-01

    Biology curricula cover fungi in units on bacteria, protists, and primitive plants, but fungi are more closely related to animals than to bacteria or plants. Like animals, fungi are heterotrophs and cannot create their own food; but, like plants, fungi have cell walls, and are for the most part immobile. Most species of fungi have a filamentous…

  15. Investigating Wound Healing in Plant Cells: This Spud's for You!

    ERIC Educational Resources Information Center

    Thomson, Norm

    2000-01-01

    Presents classroom inquiry-based investigations to investigate wound healing in plant tissues and cells. Students create their own research problems and the investigations can be related to the National Science Standards. (SAH)

  16. Developing microbial inoculants for native Hawaiian trees

    Treesearch

    Kim H. Wilkinson

    2002-01-01

    We use certain microbial inoculants in the nursery as a part of supporting the objectives of accelerating rehabilitation of degraded land and ecosystem function, as well as reducing costs in establishment and maintenance of forest plantings. Microbial inoculants re-create natural partnerships between plants and some of the beneficial microorganisms that support plants...

  17. Plantings for wildlife

    Treesearch

    Samuel B. Kirby; Claude L. Ponder; Donald J. Smith

    1989-01-01

    Grains, forages, and other vegetation can be planted to provide critical habitat for desired wildlife species or to increase habitat diversity. Plantings may be in openings created in the forest (see Note 9.11 Wildlife Openings) or along the forest edge in cultivated or pastured fields if protected from domestic livestock. The first step in determining if and what type...

  18. The Overnight Scentsation Rose Plant

    NASA Technical Reports Server (NTRS)

    1998-01-01

    International Flavors and Fragrances Inc., is a company that creates and manufactures flavors, fragrances and aroma chemicals. The Overnight Scentsation rose plant will be housed aboard NASA's shuttle flight STS-95 in a specially-designed structure under ultraviolet lights. The flowering plant was brought to Cape Canaveral from its home at IFF's greenhouse in Union Beach, New Jersey.

  19. Using the iPlant collaborative discovery environment.

    PubMed

    Oliver, Shannon L; Lenards, Andrew J; Barthelson, Roger A; Merchant, Nirav; McKay, Sheldon J

    2013-06-01

    The iPlant Collaborative is an academic consortium whose mission is to develop an informatics and social infrastructure to address the "grand challenges" in plant biology. Its cyberinfrastructure supports the computational needs of the research community and facilitates solving major challenges in plant science. The Discovery Environment provides a powerful and rich graphical interface to the iPlant Collaborative cyberinfrastructure by creating an accessible virtual workbench that enables all levels of expertise, ranging from students to traditional biology researchers and computational experts, to explore, analyze, and share their data. By providing access to iPlant's robust data-management system and high-performance computing resources, the Discovery Environment also creates a unified space in which researchers can access scalable tools. Researchers can use available Applications (Apps) to execute analyses on their data, as well as customize or integrate their own tools to better meet the specific needs of their research. These Apps can also be used in workflows that automate more complicated analyses. This module describes how to use the main features of the Discovery Environment, using bioinformatics workflows for high-throughput sequence data as examples. © 2013 by John Wiley & Sons, Inc.

  20. Characterization of microtopography and its influence on vegetation patterns in created wetlands

    USGS Publications Warehouse

    Moser, K.; Ahn, C.; Noe, G.

    2007-01-01

    Created wetlands are increasingly used to mitigate wetland loss. Thus, identifying wetland creation methods that enhance ecosystem development might increase the likelihood of mitigation success. Noting that the microtopographic variation found in natural wetland settings may not commonly be found in created wetlands, this study explores relationships between induced microtopography, hydrology, and plant species richness/ diversity in non-tidal freshwater wetlands, comparing results from two created wetland complexes with those from a mature reference wetland complex in northern Virginia. Elevation, steel rod oxidation depth, and species cover were measured along replicate multiscale (0.5 m-, 1 m-, 2 m-, and 4 m-diameter) tangentially conjoined circular transects in each wetland. Microtopography was surveyed using a total station and results used to derive three roughness indices: tortuosity, limiting slope, and limiting elevation difference. Steel rod oxidation depth was used to estimate water table depth, with data collected four times during the growing season for each study site. Plant species cover was estimated visually in 0.2 m2 plots surveyed at peak growth and used to assess species richness, diversity, and wetland prevalence index. Differences in each attribute were examined among disked and non-disked created wetlands and compared to a natural wetland as a reference. Disked and non-disked created wetlands differed in microtopography, both in terms of limiting elevation difference and tortuosity. However, both were within the range of microtopography encompassed by natural wetlands. Disked wetlands supported higher plant diversity and species richness than either natural or non-disked wetlands, as well as greater within-site species assemblage variability than non-disked wetlands. Irrespective of creation method, plant diversity in created wetlands was correlated with tortuosity and limiting elevation difference, similar to correlations observed for natural wetlands. Vegetation was more hydrophytic at disked sites than at non-disked sites, and of equivalent wetland indicator status to natural sites, even though all sites appeared comparable in terms of hydrology. Results suggest that disking may enhance vegetation community development, thus better supporting the goals of wetland mitigation. ?? 2007, The Society of Wetland Scientists.

  1. Unsedation colonoscopy can be not that painful: Evaluation of the effect of "Lamaze method of colonoscopy".

    PubMed

    Yu, Shao-Ping; Lin, Xiao-Dong; Wu, Guang-Yao; Li, Song-Hu; Wen, Zong-Quan; Cen, Xiao-Hong; Huang, Xian-Guang; Huang, Mei-Ting

    2015-10-25

    To evaluate the pain relieving effect of intervention with "Lamaze method of colonoscopy" in the process of colonoscopy. Five hundred and eighty-five patients underwent colonoscopy were randomly divided into three groups, Lamaze group, anesthetic group and control group. Two hundred and twenty-four patients of Lamaze group, the "Lamaze method of colonoscopy" were practiced in the process of colonoscopy. The Lamaze method of colonoscopy is modified from the Lamaze method of childbirth, which helped patients to relieve pain through effective breathing control. One hundred and seventy-eight patients in anesthetic group accepted sedation colonoscopy. For 183 patients in control group, colonoscopy was performed without any intervention. The satisfactory of colon cleaning, intestinal lesions, intubation time, success ratio, pain grading and complications were recorded. All data were statistically analyzed. There were no significant differences at base line of the three groups (P > 0.05). Anesthetic group shows advantage in intubation time than the other two groups (P < 0.05). Lamaze group shows no advantage in intubation time than that in control group (P > 0.05). The anesthetic group showed an apparent advantage in relieving pain (P < 0.01). Therefore, the "Lamaze method of colonoscopy" performed in colonoscopy could relieve pain effectively comparing with control group (P < 0.05). The patients in anesthetic group had the highest incidence of complications (P < 0.05). The performance of the "Lamaze method of colonoscopy" in the process of colonoscopy could relieve patients' pain, minimize the incidence of complications, and is worthy promotion in clinical practice.

  2. Oxygen relieves the CO2 and acetate dependency of Lactobacillus johnsonii NCC 533.

    PubMed

    Hertzberger, Rosanne Y; Pridmore, R David; Gysler, Christof; Kleerebezem, Michiel; Teixeira de Mattos, M Joost

    2013-01-01

    Oxygen relieves the CO2 and acetate dependency of Lactobacillus johnsonii NCC 533. The probiotic Lactobacillus johnsonii NCC 533 is relatively sensitive to oxidative stress; the presence of oxygen causes a lower biomass yield due to early growth stagnation. We show however that oxygen can also be beneficial to this organism as it relieves the requirement for acetate and CO2 during growth. Both on agar- and liquid-media, anaerobic growth of L. johnsonii NCC 533 requires CO2 supplementation of the gas phase. Switching off the CO2 supply induces growth arrest and cell death. The presence of molecular oxygen overcomes the CO2 dependency. Analogously, L. johnsonii NCC 533 strictly requires media with acetate to sustain anaerobic growth, although supplementation at a level that is 100-fold lower (120 microM) than the concentration in regular growth medium for lactobacilli already suffices for normal growth. Analogous to the CO2 requirement, oxygen supply relieves this acetate-dependency for growth. The L. johnsonii NCC 533 genome indicates that this organism lacks genes coding for pyruvate formate lyase (PFL) and pyruvate dehydrogenase (PDH), both CO2 and acetyl-CoA producing systems. Therefore, C1- and C2- compound production is predicted to largely depend on pyruvate oxidase activity (POX). This proposed role of POX in C2/C1-generation is corroborated by the observation that in a POX deficient mutant of L. johnsonii NCC 533, oxygen is not able to overcome acetate dependency nor does it relieve the CO2 dependency.

  3. Oxygen Relieves the CO2 and Acetate Dependency of Lactobacillus johnsonii NCC 533

    PubMed Central

    Hertzberger, Rosanne Y.; Pridmore, R. David; Gysler, Christof; Kleerebezem, Michiel; Teixeira de Mattos, M. Joost

    2013-01-01

    Oxygen relieves the CO2 and acetate dependency of Lactobacillus johnsonii NCC 533. The probiotic Lactobacillus johnsonii NCC 533 is relatively sensitive to oxidative stress; the presence of oxygen causes a lower biomass yield due to early growth stagnation. We show however that oxygen can also be beneficial to this organism as it relieves the requirement for acetate and CO2 during growth. Both on agar- and liquid-media, anaerobic growth of L. johnsonii NCC 533 requires CO2 supplementation of the gas phase. Switching off the CO2 supply induces growth arrest and cell death. The presence of molecular oxygen overcomes the CO2 dependency. Analogously, L. johnsonii NCC 533 strictly requires media with acetate to sustain anaerobic growth, although supplementation at a level that is 100-fold lower (120 microM) than the concentration in regular growth medium for lactobacilli already suffices for normal growth. Analogous to the CO2 requirement, oxygen supply relieves this acetate-dependency for growth. The L. johnsonii NCC 533 genome indicates that this organism lacks genes coding for pyruvate formate lyase (PFL) and pyruvate dehydrogenase (PDH), both CO2 and acetyl-CoA producing systems. Therefore, C1- and C2- compound production is predicted to largely depend on pyruvate oxidase activity (POX). This proposed role of POX in C2/C1-generation is corroborated by the observation that in a POX deficient mutant of L. johnsonii NCC 533, oxygen is not able to overcome acetate dependency nor does it relieve the CO2 dependency. PMID:23468944

  4. 25 CFR 171.405 - Can I build my own structure or take over responsibility of a BIA structure?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... written agreement between you and us which: (a) Relieves us from any future liability or responsibility for the structure; (b) Relieves us from any future costs incurred for maintaining the structure; (c) Describes what is granted by us and accepted by you; and (d) Provides that if you do not regularly use a...

  5. 25 CFR 171.405 - Can I build my own structure or take over responsibility of a BIA structure?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... written agreement between you and us which: (a) Relieves us from any future liability or responsibility for the structure; (b) Relieves us from any future costs incurred for maintaining the structure; (c) Describes what is granted by us and accepted by you; and (d) Provides that if you do not regularly use a...

  6. 5 CFR 610.406 - Holiday for employees on compressed work schedules.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... number of hours of the compressed work schedule on that day. (b) If a part-time employee is relieved or... of the compressed work schedule on that day. When a holiday falls on a nonworkday of a part-time... work schedules. (a) If a full-time employee is relieved or prevented from working on a day designated...

  7. Acute Erycibe henryi Prain ("Ting Kung Teng") poisoning.

    PubMed

    Huang, Hsien-Hao; Yen, David Hung-Tsang; Wu, Ming-Ling; Deng, Jou-Fang; Huang, Chun-I; Lee, Chen-Hsen

    2006-01-01

    Erycibe henryi Prain ("Ting Kung Teng"), a species of Convolvulaceae, has been used in Chinese medicine to relieve pain involving the musculoskeletal system, such as arthritis, sciatica, and traumatic tissue swelling. E. henryi can be mistaken for another herbal plant, Tripterygium wilfordii Hook F, used to treat gouty arthritis. We report here three cases of E. henryi poisoning. All three cases presented with vomiting, diarrhea, salivation, diaphoresis, lacrimation, and rhinorrhea; two patients also had miosis, hypothermia, bradycardia, hypotension, and ventricular tachyarrhythmias. Laboratory abnormalities included leucocytosis, hyperglycemia, hyperamylasemia, hypocalcemia, and transiently elevated liver enzymes, creatinine and creatinine phosphokinase. The active constituents of E. henryi include several tropane alkaloids, which exhibit cholinergic activities. Gastrointestinal disturbances and ventricular tachyarrhythmias may occur with ingestion of either E. henryi or T. wilfordii, but the cholinergic symptoms can help to differentiate them.

  8. Facilitation of survival and growth of Baccharis halimifolia L. by Spartina alterniflora Loisel. in a created Louisiana salt marsh

    USGS Publications Warehouse

    Egerova, J.; Proffitt, C.E.; Travis, S.E.

    2003-01-01

    Coastal wetland loss is a major environmental issue in the Mississippi Delta region of the southern United States, where grasses such as Spartina alterniflora may play a critical role both as early colonizers on created sites and as facilitators of other marsh grasses and shrubs, particularly at high intertidal elevations. We explored the potential role of S. alterniflora as a facilitator of the colonization and growth of the shrub Baccharis halimifolia at two created wetlands in southwestern Louisiana through a combination of plant surveys and experimentation. Surveys for the presence of B. halimifolia inside and outside the bare centers of S. alterniflora clones that had begun to senesce inwardly were conducted at a 4-yr-old site originally created in 1993. The percent of clones containing B. halimifolia and the number of individual B. halimifolia plants per clone increased with increasing S. alterniflora clone size and decreased with increasing distance from an adjacent containment berm. Two experiments conducted at a second 4-yr-old site that originally created in 1996 were designed to assess seed capture and growth of seedlings of B. halimifolia inside S. alterniflora clones. These experiments revealed that while significantly fewer seeds settle inside clones, those seedlings that grow in such areas gain a clear advantage in terms of both survival and rate of growth, which helps to explain the results of the initial survey and testifies to the role of S. alterniflora as a nurse plant in newly-created high intertidal marshes.

  9. Ontology-based prediction of surgical events in laparoscopic surgery

    NASA Astrophysics Data System (ADS)

    Katić, Darko; Wekerle, Anna-Laura; Gärtner, Fabian; Kenngott, Hannes; Müller-Stich, Beat Peter; Dillmann, Rüdiger; Speidel, Stefanie

    2013-03-01

    Context-aware technologies have great potential to help surgeons during laparoscopic interventions. Their underlying idea is to create systems which can adapt their assistance functions automatically to the situation in the OR, thus relieving surgeons from the burden of managing computer assisted surgery devices manually. To this purpose, a certain kind of understanding of the current situation in the OR is essential. Beyond that, anticipatory knowledge of incoming events is beneficial, e.g. for early warnings of imminent risk situations. To achieve the goal of predicting surgical events based on previously observed ones, we developed a language to describe surgeries and surgical events using Description Logics and integrated it with methods from computational linguistics. Using n-Grams to compute probabilities of followup events, we are able to make sensible predictions of upcoming events in real-time. The system was evaluated on professionally recorded and labeled surgeries and showed an average prediction rate of 80%.

  10. Fungal Beta-Glucosidases: A Bottleneck in Industrial Use of Lignocellulosic Materials

    PubMed Central

    Sørensen, Annette; Lübeck, Mette; Lübeck, Peter S.; Ahring, Birgitte K.

    2013-01-01

    Profitable biomass conversion processes are highly dependent on the use of efficient enzymes for lignocellulose degradation. Among the cellulose degrading enzymes, beta-glucosidases are essential for efficient hydrolysis of cellulosic biomass as they relieve the inhibition of the cellobiohydrolases and endoglucanases by reducing cellobiose accumulation. In this review, we discuss the important role beta-glucosidases play in complex biomass hydrolysis and how they create a bottleneck in industrial use of lignocellulosic materials. An efficient beta-glucosidase facilitates hydrolysis at specified process conditions, and key points to consider in this respect are hydrolysis rate, inhibitors, and stability. Product inhibition impairing yields, thermal inactivation of enzymes, and the high cost of enzyme production are the main obstacles to commercial cellulose hydrolysis. Therefore, this sets the stage in the search for better alternatives to the currently available enzyme preparations either by improving known or screening for new beta-glucosidases. PMID:24970184

  11. Ultra-sharp plasmonic resonances from monopole optical nanoantenna phased arrays

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Li, Shi-Qiang; Bruce Buchholz, D.; Zhou, Wei

    Diffractively coupled plasmonic resonances possess both ultra-sharp linewidths and giant electric field enhancement around plasmonic nanostructures. They can be applied to create a new generation of sensors, detectors, and nano-optical devices. However, all current designs require stringent index-matching at the resonance condition that limits their applicability. Here, we propose and demonstrate that it is possible to relieve the index-matching requirement and to induce ultra-sharp plasmon resonances in an ordered vertically aligned optical nano-antenna phased array by transforming a dipole resonance to a monopole resonance with a mirror plane. Due to the mirror image effect, the monopole resonance not only retainedmore » the dipole features but also enhanced them. The engineered resonances strongly suppressed the radiative decay channel, resulting in a four-order of magnitude enhancement in local electric field and a Q-factor greater than 200.« less

  12. Procedural pain management for neonates using nonpharmacological strategies: Part 1: sensorial interventions.

    PubMed

    Fernandes, Ananda; Campbell-Yeo, Marsha; Johnston, C Celeste

    2011-08-01

    Neonates who are born preterm and are admitted to neonatal intensive care units endure frequent procedures that may be painful. Nonpharmacological interventions that have been studied to relieve their pain may be categorized in 2 main groups according to their nature: interventions that focus on creating a favorable environment and offering pleasant sensorial stimuli and interventions that are centered on maternal care. These interventions may be considered within the philosophy of developmental care, since they are aimed at adjusting the environment to the needs of the neonate and involve family-centered care. In this article, the first of a 2-part series, we will synthesize the evidence from experimental studies of interventions that focus on the environment and on tactile and gustatory stimulation. The mechanisms suggested by researchers as possible explanations for the efficacy of these interventions are pointed, and the implications for procedural pain management in neonatal care are drawn.

  13. The integral role of food in Native Hawaiian migrants' perceptions of health and well-being.

    PubMed

    Lassetter, Jane H

    2011-01-01

    Obesity is prevalent among Native Hawaiians, but the relationship between food and perceptions of health and well-being is not well understood. The purpose was to explore the role of food in Native Hawaiians' perceptions of health and well-being. A qualitative descriptive design was used. Twenty-seven Native Hawaiian participants in Las Vegas took part in semistructured interviews. Participants expressed that food can be dangerous to health. However, eating Hawaiian food seems to relieve homesickness, and they occasionally indulge in binge overeating. Hawaiian food plays an important role in participants' health and well-being. Participants' concurrent attraction to Hawaiian-style food and desire to avoid unhealthy food create a challenging struggle. To support cultural connectedness, Native Hawaiians can be encouraged to expend consumed calories in physical activity as their ancestors did. Discussing nutrition from a family framework might be helpful to Native Hawaiians.

  14. Risk and danger among women-who-prostitute in areas where farmworkers predominate.

    PubMed

    Bletzer, Keith V

    2003-06-01

    Based on ethnographic research in three agricultural settings in Florida, this article examines one aspect of risk and danger for female sex workers, that of interpersonal violence, while considering women's responses to a shifting sex trade in areas where farmworkers live and work. Sex work in agricultural areas varies from urban sex work. Women eschew pimps, ask for backup from local men entrenched in street settings, and canvass a wide spatial area rather than remained fixed in space. Oscillating between periods of capital-deficiency (nonseason) and capital-intensification (harvest), women respond to increasing risk and danger by building a clientele of regular customers, refusing risky transactions and referrals, and creating a local infrastructure of sanctuary. Some women also construct schemes to relieve men of their money. These men typically are farmworkers, whose vulnerability and image of low risk for HIV expands the potential for risk and danger found in these settings.

  15. Traditional Arabic Palestinian ethnoveterinary practices in animal health care: A field survey in the West Bank (Palestine).

    PubMed

    Ali-Shtayeh, Mohammed S; Jamous, Rana M; Jamous, Rania M

    2016-04-22

    In Palestine, medicinal plants have continued to play a vital role in fulfilling animal healthcare needs of rural communities. However, these valuable resources are being depleted mainly due to over-harvesting, inappropriate agricultural practices (e.g., over use of herbicides), agricultural expansion, and over-grazing. Therefore, immediate action is required to conserve these resources and document the associated knowledge. The purpose of this study was, thus, to document and analyze information associated with medicinal plants that are used in managing animal health problems in the West Bank, Palestine. Ethnobotanical data were collected from Apr 2012 to Feb 2014 mainly using semi-structured interviews with informants sampled using purposive sampling technique and through field observations. The study revealed the use of 138 medicinal plant species in the West Bank for the treatment of several livestock diseases, of these 75 species representing 70 genera and 33 families were reported by 3 independent informants or above. Classification of the ethnoveterinary plant species cited by three informants or above used in a rank-order priority (ROP) based on their claimed relative healing potential has demonstrated that the following are the plants with the highest efficacy: Camellia sinenses, Teucrium capitatum, and Salvia fruticosa with ROPs of 97.1, 93.2, and 91.4, respectively, are used primarily to relieve gastric disorders. Gastrointestinal disorders is the disease group in the study area that scored the highest Informant consensus factor (ICF) value (0.90), followed by urinary, and reproductive disorders (0.89). Our study provided evidence that medicinal plants are still playing important role in the management of livestock diseases, and showed that ethnoveterinary plants used in animal health care in Palestine have been also recorded in human Traditional Arabic Palestinian Herbal Medicine (TAPHM), and demonstrated a strong link between human and veterinary medical practices. This survey has identified a number of important medicinal plants used by the Palestinian farmers of the West Bank area for the treatment of various animal ailments. It provides a baseline for future phytochemical and pharmacological investigations into the beneficial medicinal properties of such plants. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  16. Power Watch: Increasing Transparency and Accessibility of Data in the Global Power Sector to Accelerate the Transition to a Lower Carbon Economy

    NASA Astrophysics Data System (ADS)

    Hennig, R. J.; Friedrich, J.; Malaguzzi Valeri, L.; McCormick, C.; Lebling, K.; Kressig, A.

    2016-12-01

    The Power Watch project will offer open data on the global electricity sector starting with power plants and their impacts on climate and water systems; it will also offer visualizations and decision making tools. Power Watch will create the first comprehensive, open database of power plants globally by compiling data from national governments, public and private utilities, transmission grid operators, and other data providers to create a core dataset that has information on over 80% of global installed capacity for electrical generation. Power plant data will at a minimum include latitude and longitude, capacity, fuel type, emissions, water usage, ownership, and annual generation. By providing data that is both comprehensive, as well as making it publically available, this project will support decision making and analysis by actors across the economy and in the research community. The Power Watch research effort focuses on creating a global standard for power plant information, gathering and standardizing data from multiple sources, matching information from multiple sources on a plant level, testing cross-validation approaches (regional statistics, crowdsourcing, satellite data, and others) and developing estimation methodologies for generation, emissions, and water usage. When not available from official reports, emissions, annual generation, and water usage will be estimated. Water use estimates of power plants will be based on capacity, fuel type and satellite imagery to identify cooling types. This analysis is being piloted in several states in India and will then be scaled up to a global level. Other planned applications of of the Power Watch data include improving understanding of energy access, air pollution, emissions estimation, stranded asset analysis, life cycle analysis, tracking of proposed plants and curtailment analysis.

  17. 50 CFR 260.100 - Facilities.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Products for Human Consumption Requirements for Plants Operating Under Continuous Inspection on A Contract... or material not intended for human food or which creates an objectionable condition shall be... locations throughout the plant. [36 FR 21040, Nov. 3, 1971] ...

  18. 50 CFR 260.100 - Facilities.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Products for Human Consumption Requirements for Plants Operating Under Continuous Inspection on A Contract... or material not intended for human food or which creates an objectionable condition shall be... locations throughout the plant. [36 FR 21040, Nov. 3, 1971] ...

  19. Hydroponics--Studies in Plant Culture With Historical Roots.

    ERIC Educational Resources Information Center

    Lopez, Luz Maria

    1981-01-01

    Presents methods for demonstrating and applying scientific principles by growing plants through water culture (hydroponics), including a review of the history of hydroponics, re-creating some early experiments, and setting up a modern hydroponic system. (CS)

  20. Genetically engineered foods

    MedlinePlus

    ... insert that gene into a cell of another plant or animal. ... Bioengineered foods; GMOs; Genetically modified foods ... also be moved from an animal to a plant or vice versa. Another ... organisms, or GMOs. The process to create GE foods is different ...

  1. Medical Marijuana in Certain Neurological Disorders

    MedlinePlus

    ... of chemicals in the plant: cannabidiol (CBD) and tetrahydrocannabinol (THC). CBD and THC are taken from the cannabis plant for use ... also can be created (synthesized) in a lab. THC has a stronger intoxicating effect than CBD. Is ...

  2. Floristic summary of North American plant species in the air pollution literature

    USGS Publications Warehouse

    Bennett, J.P.; Yunus, M.; Singh, N.; de Kok, L. J.

    2000-01-01

    Notes are given on a project to create a database of bibliographic information, abstracts and keywords for publications on the biological effects of gaseous and heavy metal air pollution on plants and lichens.

  3. [Progress on painful diabetic peripheral neuropathy treated by integrative medicine].

    PubMed

    Hong, Hong-Bin; Xu, Rong-Juan

    2005-04-01

    The article reviewed clinical studies on painful diabetic peripheral neuropathy (PDPN) treated by integrative medicine. PDPN, a common complication of diabetes mellitus, which could severely influence patients' quality of life. The keystone and difficulty of PDPN treatment is to relieve pain. Tricyclic anti-depressants are the firstline agents for neuropathic pain but with obvious adverse reactions. Antiepileptic drugs and capsicin can relieve PDPN with less adverse reactions. In recent years, lots of report of clinical studies on DPN treated by TCM or integrative medicine were issued, but those pertinent to PDPN were seldom. Only the papers with independent statistical analysis on effect of pain relieving were selected to review in this article, and the authors presumed that it is feasible to treat PDPN with integrative medicine.

  4. The Research on the Impact of Green Beans Sports Drinks on Relieving Fatigue in Sports Training.

    PubMed

    Qi, Li; Ying, Liu

    2015-01-01

    For researching the function of relieving fatigue of green beans sports drinks, this paper selected 60 mice as subjects. They were randomly divided into four groups (low dose group, middle dose group, high dose group and physiological saline group). Each time they were respectively feed 10g 20g/L, 40g/L, 80 g/L green beans sports drinks and 15ml/(kg.d) physiological saline. The experiment lasted for a month. We recorded weight of mice, swimming time and blood urea nitrogen indicators. The results show that green beans sports drinks can significantly prolong swimming time of mice (p <0.05). For serum urea the results show no effect. So green beans sports drinks have a certain function of relieving physical fatigue.

  5. Automatic stress-relieving music recommendation system based on photoplethysmography-derived heart rate variability analysis.

    PubMed

    Shin, Il-Hyung; Cha, Jaepyeong; Cheon, Gyeong Woo; Lee, Choonghee; Lee, Seung Yup; Yoon, Hyung-Jin; Kim, Hee Chan

    2014-01-01

    This paper presents an automatic stress-relieving music recommendation system (ASMRS) for individual music listeners. The ASMRS uses a portable, wireless photoplethysmography module with a finger-type sensor, and a program that translates heartbeat signals from the sensor to the stress index. The sympathovagal balance index (SVI) was calculated from heart rate variability to assess the user's stress levels while listening to music. Twenty-two healthy volunteers participated in the experiment. The results have shown that the participants' SVI values are highly correlated with their prespecified music preferences. The sensitivity and specificity of the favorable music classification also improved as the number of music repetitions increased to 20 times. Based on the SVI values, the system automatically recommends favorable music lists to relieve stress for individuals.

  6. Control of invasive plant species in created wetlands.

    DOT National Transportation Integrated Search

    1994-01-01

    The Virginia Department of Transportation (VDOT) has been using a herbicide in the form of glyphosate for the control of unwanted species in created wetlands. Results with this particular herbicide have been somewhat mixed. It was requested that the ...

  7. Environmental implications of jatropha biofuel from a silvi-pastoral production system in central-west Brazil.

    PubMed

    Bailis, Rob; Kavlak, Goksin

    2013-07-16

    We present a life cycle assessment of synthetic paraffinic kerosene produced from Jatropha curcas. The feedstock is grown in an intercropping arrangement with pasture grasses so that Jatropha is coproduced with cattle. Additional innovations are introduced including hybrid seeds, detoxification of jatropha seedcake, and cogeneration. Two fuel pathways are examined including a newly developed catalytic decarboxylation process. Sensitivities are examined including higher planting density at the expense of cattle production as well as 50% lower yields. Intercropping with pasture and detoxifying seedcake yield coproducts that are expected to relieve pressure on Brazil's forests and indirectly reduce environmental impacts of biofuel production. Other innovations also reduce impacts. Results of the baseline assessment indicate that innovations would reduce impacts relative to the fossil fuel reference scenario in most categories including 62-75% reduction in greenhouse gas emissions, 64-82% reduction in release of ozone depleting chemicals, 33-52% reduction in smog-forming pollutants, 6-25% reduction in acidification, and 60-72% reduction in use of nonrenewable energy. System expansion, which explicitly accounts for avoided deforestation, results in larger improvements. Results are robust across allocation methodologies, improve with higher planting density, and persist if yield is reduced by half.

  8. Functional FRIGIDA allele enhances drought tolerance by regulating the P5CS1 pathway in Arabidopsis thaliana.

    PubMed

    Chen, Qian; Zheng, Yan; Luo, Landi; Yang, Yongping; Hu, Xiangyang; Kong, Xiangxiang

    2018-01-01

    Flowering at the right time is important for the reproductive success of plants and their response to environmental stress. In Arabidopsis, a major determinant of natural variation in flowering time is FRIGIDA (FRI). In the present study, we show that overexpression of the functional FRIGIDA gene in wild-type Col background (ColFRI) positively enhances the drought tolerance by activating P5CS1 expression and promoting proline accumulation during water stress. Furthermore, no significant changes in FRI gene and protein expression levels were observed with drought treatment, whereas P5CS1 protein expression significantly increased. In contrast, vernalization treatment efficiently reduced P5CS1 expression levels and resulted in a decrease in drought tolerance in the ColFRI plants. The flc mutants with a functional FRI background also relieved FRI-mediated activation of P5CS1 during drought tolerance. Taken together, our findings reveal the novel function of FRI in enhancing drought resistance through its downstream P5CS1 pathway during water-deficit stress, which is dependent on its target, the FLC gene. Copyright © 2017 Elsevier Inc. All rights reserved.

  9. 78 FR 59681 - New York State Prohibition of Discharges of Vessel Sewage; Receipt of Petition and Tentative...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-27

    ... globally rare plants and animals and more than 40 species that are found nowhere else in the world. Lake... in the amount of effluent discharged from sewage treatment plants. There are 18 designated... wastewater treatment plant or to an on-site septic system. All fifteen were created through funding provided...

  10. 77 FR 63439 - Endangered and Threatened Wildlife and Plants; Proposed Endangered Status for the Neosho Mucket...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-16

    ... Service 50 CFR Part 17 Endangered and Threatened Wildlife and Plants; Proposed Endangered Status for the... No. FWS-ES-R4-2012-0031; 4500030113] RIN 1018-AX73 Endangered and Threatened Wildlife and Plants... stress (stream's ability to entrain and transport bed material created by the flow acting on the bed...

  11. Native plant restoration on the Going-to-the-Sun Road, Glacier National Park

    Treesearch

    David E. Lange; Joyce Lapp

    1999-01-01

    Since 1991, 53 acres of roadside vegetation and soil were removed along sections of the historic Going-to-the-Sun Road during road rehabilitation activities. Restoration strategies used indigenous plant material to re-establish plant cover, prevent erosion, compete with exotics, and improve aesthetics. From several hundred collections, simple seed mixes were created...

  12. Meeting the challenge: invasive plants in Pacific Northwest ecosystems.

    Treesearch

    Timothy B. Harrington; Sarah H. Reichard

    2007-01-01

    During September 19-20, 2006, a conference was held at the University of Washington Botanic Gardens, Seattle, WA, with the title "Meeting the challenge: invasive plants in Pacific Northwest Ecosystems." The mission of the conference was to create strategies and partnerships to understand and manage invasions of non-native plants in the Pacific Northwest. The...

  13. Factors driving natural regeneration beneath a planted urban forest

    Treesearch

    Danica A. Doroski; Alexander J. Felson; Mark A. Bradford; Mark P. Ashton; Emily E. Oldfield; Richard A. Hallett; Sara E. Kuebbing

    2018-01-01

    Cities around the world are investing in urban forest plantings as a form of green infrastructure. The aim is that these plantations will develop into naturally-regenerating native forest stands. However, woody plant recruitment is often cited as the most limiting factor to creating self-sustaining urban forests. As such, there is interest in site treatments that...

  14. The Australian health policy changes of 1999 and 2000: an evaluation.

    PubMed

    Hopkins, Sandra; Zweifel, Peter

    2005-01-01

    This article evaluates three measures introduced by the Australian Federal Government in 1999 and 2000 that were designed to encourage private health insurance and relieve financial pressure on the public healthcare sector. These policy changes were (i) a 30% premium rebate, (ii) health insurers offering lifetime enrolment on existing terms and the future relaxation of premium regulation by permitting premiums to increase with age, and (iii) a mandate for insurers to offer complementary coverage for bridging the gap between actual hospital billings and benefits paid. These measures were first evaluated in terms of expected benefits and costs at the individual level. In terms of the first criteria, the policy changes as a whole may have been efficiency-increasing. The Australian Government mandate to launch gap policies may well have created a spillover moral hazard effect to the extent that full insurance coverage encouraged policy holders to also use more public hospital services, thus undermining the government's stated objective to relieve public hospitals from demand pressure. Without this spillover moral hazard effect, there might have been a reduction in waiting times in the public sector. Secondly, the measures were evaluated in terms of additional benchmarks of the cost to the public purse, access and equity, and dynamic efficiency. Although public policy changes were found to be largely justifiable on the first set of criteria, they do not appear to be justifiable based on the second set. Uncertainties and doubts remain about the effect of the policy changes in terms of overall cost, access and equity, and dynamic efficiency. This is a common experience in countries that have considered shifts of their healthcare systems between the private and public sectors.

  15. A shape memory airway stent for tracheobronchomalacia in children: an experimental and clinical study.

    PubMed

    Tsugawa, C; Nishijima, E; Muraji, T; Yoshimura, M; Tsubota, N; Asano, H

    1997-01-01

    The authors have designed a coil airway stent using a thermal shape-memory titanium-nickel alloy (SMA) to relieve airway collapse in children. A characteristic of alloy allowed the stent to be enclosed in the thin introducer tube and to position it bronchoscopically in the collapsed airway. When the stent is warmed to 37 to 40 degrees C, it expands to the memorized diameter and stents the airway. In eight rabbits, an experimental model of potentially fatal tracheomalacia was created by fracturing the tracheal cartilages. The stents of 6 mm in diameter and 15 mm in length were placed, and then the stents were recovered to their original shape within 1 minute. All rabbits except one showed no respiratory symptoms during the follow-up period. Results of bronchoscopy performed 6 and 10 months after implantation showed satisfactory patency of the trachea. The rabbits were killed for histological evaluation 6 to 28 months after implantation. The specimens showed little proliferation of granulation and no dislodgement of the stents. This procedure was attempted in two children who had severe bronchomalacia. One 5-year-old patient underwent implantation with a stent of 5 mm in diameter and 25 mm in length into the left main bronchus. The patient was relieved from apneic attacks. The stent was removed 2 years after implantation after a remarkable improvement of ventilation. The other patient with left bronchomalacia, age 1 year 2 months, underwent implantation with a 5-mm x 20-mm stent. The animal experiment and clinical experience indicated that (1) this stent can be easily inserted and removed bronchoscopically, (2) the stent has good tissue compatibility and little interference of mucociliary function, and (3) the SMA stent is a promising therapeutic adjunct in the management of children with severe tracheobronchomalacia.

  16. Evidence for cognitive–behavioral strategies improving dyspnea and related distress in COPD

    PubMed Central

    Norweg, Anna; Collins, Eileen G

    2013-01-01

    Background Dyspnea is a complex, prevalent, and distressing symptom of chronic obstructive pulmonary disease (COPD) associated with decreased quality of life, significant disability, and increased mortality. It is a major reason for referral to pulmonary rehabilitation. Methods We reviewed 23 COPD studies to examine the evidence for the effectiveness of cognitive–behavioral strategies for relieving dyspnea in COPD. Results Preliminary evidence from randomized controlled trials exists to support cognitive– behavioral strategies, used with or without exercise, for relieving sensory and affective components of dyspnea in COPD. Small to moderate treatment effects for relieving dyspnea were noted for psychotherapy (effect size [ES] = 0.08–0.25 for intensity; 0.26–0.65 for mastery) and distractive auditory stimuli (ES = 0.08–0.33 for intensity; 0.09 to −0.61 for functional burden). Small to large dyspnea improvements resulted from yoga (ES = 0.2–1.21 for intensity; 0.67 for distress; 0.07 for mastery; and −8.37 for functional burden); dyspnea self-management education with exercise (ES = −0.14 to −1.15 for intensity; −0.62 to −0.69 for distress; 1.04 for mastery; 0.14–0.35 for self-efficacy); and slow-breathing exercises (ES = −0.34 to −0.83 for intensity; −0.61 to −0.80 for distress; and 0.62 for self-efficacy). Cognitive–behavioral interventions may relieve dyspnea in COPD by (1) decreasing sympathetic nerve activity, dynamic hyperinflation, and comorbid anxiety, and (2) promoting arterial oxygen saturation, myelinated vagus nerve activity, a greater exercise training effect, and neuroplasticity. Conclusion While evidence is increasing, additional randomized controlled trials are needed to evaluate the effectiveness of psychosocial and self-management interventions in relieving dyspnea, in order to make them more available to patients and to endorse them in official COPD, dyspnea, and pulmonary rehabilitation practice guidelines. By relieving dyspnea and related anxiety, such interventions may promote adherence to exercise programs and adaptive lifestyle change. PMID:24106423

  17. Real-life use of budesonide/formoterol in clinical practice: a 12-month follow-up assessment in a multi-national study of asthma patients established on single-inhaler maintenance and reliever therapy

    PubMed Central

    Ställberg, Björn; Naya, Ian; Ekelund, Jan; Eckerwall, Göran

    2015-01-01

    Objective: The efficacy and safety of budesonide/formoterol maintenance and reliever therapy (MRT) has been demonstrated in phase III clinical studies, but limited data are available in a real-life setting. We examined the pattern of maintenance and as-needed inhaler use in routine clinical practice among patients with asthma receiving budesonide/formoterol MRT (NCT00505388). Methods: This 12-month European observational study enrolled patients prescribed budesonide/formoterol MRT and grouped them based on regimen: 80/4.5 µg one inhalation twice daily (b.i.d.); 160/4.5 µg one inhalation b.i.d.; 160/4.5 µg two inhalations b.i.d. (all plus as needed). Patient data were collected daily using an interactive voice- or web-response system. The primary outcome measure was total number of budesonide/formoterol inhalations/day. Results: Overall, 4,581 patients were included (64% female; mean age 48.4 years; regimen: 80/4.5 µg, n = 119; 160/4.5 µg, n = 3,106; 2 × 160/4.5 µg, n = 1,355). Mean (median) total numbers of budesonide/formoterol inhalations/day were 2.48 (2.11), 2.53 (2.14), and 4.27 (4.05) for 80/4.5 µg b.i.d., 160/4.5 µg b.i.d., and 2 × 160/4.5 µg b.i.d., respectively; corresponding mean (median) number of as-needed inhalations/day were 0.68 (0.17), 0.73 (0.26), and 1.08 (0.45), respectively. As-needed budesonide/formoterol use was generally low with a mean of 61 – 66% of reliever-free days; over 4 reliever inhalations/day occurred on a mean of 0.4 – 2.5% of days for all budesonide/formoterol MRT regimens. Conclusions: In routine clinical practice, all budesonide/formoterol MRT regimens were associated with a high proportion of reliever-free days and low incidence of high reliever-use days, indicating acceptable levels of asthma control with this symptom-adjusted controller regimen. PMID:25907171

  18. Real-life use of budesonide/formoterol in clinical practice: a 12-month follow-up assessment in a multi-national study of asthma patients established on single-inhaler maintenance and reliever therapy.

    PubMed

    Ställberg, Björn; Naya, Ian; Ekelund, Jan; Eckerwall, Göran

    2015-06-01

    The efficacy and safety of budesonide/formoterol maintenance and reliever therapy (MRT) has been demonstrated in phase III clinical studies, but limited data are available in a real-life setting. We examined the pattern of maintenance and as-needed inhaler use in routine clinical practice among patients with asthma receiving budesonide/formoterol MRT (NCT00505388). This 12-month European observational study enrolled patients prescribed budesonide/formoterol MRT and grouped them based on regimen: 80/4.5 μg one inhalation twice daily (b.i.d.); 160/4.5 μg one inhalation b.i.d.; 160/4.5 μg two inhalations b.i.d. (all plus as needed). Patient data were collected daily using an interactive voice- or web-response system. The primary outcome measure was total number of budesonide/formoterol inhalations/day. Overall, 4,581 patients were included (64% female; mean age 48.4 years; regimen: 80/4.5 μg, n = 119; 160/4.5 μg, n = 3,106; 2 x 160/4.5 μg, n = 1,355). Mean (median) total numbers of budesonide/formoterol inhalations/day were 2.48 (2.11), 2.53 (2.14), and 4.27 (4.05) for 80/4.5 μg b.i.d., 160/4.5 μg b.i.d., and 2 x 160/4.5 μg b.i.d., respectively; corresponding mean (median) number of as-needed inhalations/day were 0.68 (0.17), 0.73 (0.26), and 1.08 (0.45), respectively. As-needed budesonide/formoterol use was generally low with a mean of 61 - 66% of reliever-free days; over 4 reliever inhalations/day occurred on a mean of 0.4 - 2.5% of days for all budesonide/formoterol MRT regimens. Inroutine clinical practice, all budesonide/formoterol MRT regimens were associated with a high proportion of reliever-free days and low incidence of high reliever-use days, indicating acceptable levels of asthma control with this symptom-adjusted controller regimen.

  19. Bioengineering recombinant tung tree diacylglycerol acyltransferases

    USDA-ARS?s Scientific Manuscript database

    Understanding plant oil biosynthesis will help to create new oilseed crops with value-added properties to replace petroleum-based compounds. Diacylglycerol acyltransferases (DGATs) are key enzymes catalyzing the last step of triacylglycerol (TAG) biosynthesis in eukaryotes. Plants and animals defici...

  20. The Challenges of Creating a Real-Time Data Management System for TRU-Mixed Waste at the Advanced Mixed Waste Treatment Plant

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Paff, S. W; Doody, S.

    2003-02-25

    This paper discusses the challenges associated with creating a data management system for waste tracking at the Advanced Mixed Waste Treatment Plant (AMWTP) at the Idaho National Engineering Lab (INEEL). The waste tracking system combines data from plant automation systems and decision points. The primary purpose of the system is to provide information to enable the plant operators and engineers to assess the risks associated with each container and determine the best method of treating it. It is also used to track the transuranic (TRU) waste containers as they move throughout the various processes at the plant. And finally, themore » goal of the system is to support paperless shipments of the waste to the Waste Isolation Pilot Plant (WIPP). This paper describes the approach, methodologies, the underlying design of the database, and the challenges of creating the Data Management System (DMS) prior to completion of design and construction of a major plant. The system was built utilizing an Oracle database platform, and Oracle Forms 6i in client-server mode. The underlying data architecture is container-centric, with separate tables and objects for each type of analysis used to characterize the waste, including real-time radiography (RTR), non-destructive assay (NDA), head-space gas sampling and analysis (HSGS), visual examination (VE) and coring. The use of separate tables facilitated the construction of automatic interfaces with the analysis instruments that enabled direct data capture. Movements are tracked using a location system describing each waste container's current location and a history table tracking the container's movement history. The movement system is designed to interface both with radio-frequency bar-code devices and the plant's integrated control system (ICS). Collections of containers or information, such as batches, were created across the various types of analyses, which enabled a single, cohesive approach to be developed for verification and validation activities. The DMS includes general system functions, including task lists, electronic signature, non-conformance reports and message systems, that cut vertically across the remaining subsystems. Oracle's security features were utilized to ensure that only authorized users were allowed to log in, and to restrict access to system functionality according to user role.« less

  1. Toxicity and tolerance of aluminum in plants: tailoring plants to suit to acid soils.

    PubMed

    Sade, Hemalatha; Meriga, Balaji; Surapu, Varalakshmi; Gadi, Jogeswar; Sunita, M S L; Suravajhala, Prashanth; Kavi Kishor, P B

    2016-04-01

    Aluminum (Al) stress is one of the serious limiting factors in plant productivity in acidic soils, which constitute about 50 % of the world's potentially arable lands and causes anywhere between 25 and 80 % of yield losses depending upon the species. The mechanism of Al toxicity and tolerance has been examined in plants, which is vital for crop improvement and enhanced food production in the future. Two mechanisms that facilitate Al tolerance in plants are Al exclusion from the roots and the ability to tolerate Al in the symplast or both. Although efforts have been made to unravel Al-resistant factors, many aspects remain unclear. Certain gene families such as MATE, ALMT, ASR, and ABC transporters have been implicated in some plants for resistance to Al which would enhance the opportunities for creating crop plants suitable to grow in acidic soils. Though QTLs have been identified related to Al-tolerance, no crop plant that is tolerant to Al has been evolved so far using breeding or molecular approaches. The remarkable changes that plants experience at the physiological, biochemical and molecular level under Al stress, the vast array of genes involved in Al toxicity-tolerance, the underlying signaling events and the holistic image of the molecular regulation, and the possibility of creating transgenics for Al tolerance are discussed in this review.

  2. Augmenting Transport versus Increasing Cold Storage to Improve Vaccine Supply Chains

    PubMed Central

    Haidari, Leila A.; Connor, Diana L.; Wateska, Angela R.; Brown, Shawn T.; Mueller, Leslie E.; Norman, Bryan A.; Schmitz, Michelle M.; Paul, Proma; Rajgopal, Jayant; Welling, Joel S.; Leonard, Jim; Chen, Sheng-I; Lee, Bruce Y.

    2013-01-01

    Background When addressing the urgent task of improving vaccine supply chains, especially to accommodate the introduction of new vaccines, there is often a heavy emphasis on stationary storage. Currently, donations to vaccine supply chains occur largely in the form of storage equipment. Methods This study utilized a HERMES-generated detailed, dynamic, discrete event simulation model of the Niger vaccine supply chain to compare the impacts on vaccine availability of adding stationary cold storage versus transport capacity at different levels and to determine whether adding stationary storage capacity alone would be enough to relieve potential bottlenecks when pneumococcal and rotavirus vaccines are introduced by 2015. Results Relieving regional level storage bottlenecks increased vaccine availability (by 4%) more than relieving storage bottlenecks at the district (1% increase), central (no change), and clinic (no change) levels alone. Increasing transport frequency (or capacity) yielded far greater gains (e.g., 15% increase in vaccine availability when doubling transport frequency to the district level and 18% when tripling). In fact, relieving all stationary storage constraints could only increase vaccine availability by 11%, whereas doubling the transport frequency throughout the system led to a 26% increase and tripling the frequency led to a 30% increase. Increasing transport frequency also reduced the amount of stationary storage space needed in the supply chain. The supply chain required an additional 61,269L of storage to relieve constraints with the current transport frequency, 55,255L with transport frequency doubled, and 51,791L with transport frequency tripled. Conclusions When evaluating vaccine supply chains, it is important to understand the interplay between stationary storage and transport. The HERMES-generated dynamic simulation model showed how augmenting transport can result in greater gains than only augmenting stationary storage and can reduce stationary storage needs. PMID:23717590

  3. Augmenting transport versus increasing cold storage to improve vaccine supply chains.

    PubMed

    Haidari, Leila A; Connor, Diana L; Wateska, Angela R; Brown, Shawn T; Mueller, Leslie E; Norman, Bryan A; Schmitz, Michelle M; Paul, Proma; Rajgopal, Jayant; Welling, Joel S; Leonard, Jim; Chen, Sheng-I; Lee, Bruce Y

    2013-01-01

    When addressing the urgent task of improving vaccine supply chains, especially to accommodate the introduction of new vaccines, there is often a heavy emphasis on stationary storage. Currently, donations to vaccine supply chains occur largely in the form of storage equipment. This study utilized a HERMES-generated detailed, dynamic, discrete event simulation model of the Niger vaccine supply chain to compare the impacts on vaccine availability of adding stationary cold storage versus transport capacity at different levels and to determine whether adding stationary storage capacity alone would be enough to relieve potential bottlenecks when pneumococcal and rotavirus vaccines are introduced by 2015. Relieving regional level storage bottlenecks increased vaccine availability (by 4%) more than relieving storage bottlenecks at the district (1% increase), central (no change), and clinic (no change) levels alone. Increasing transport frequency (or capacity) yielded far greater gains (e.g., 15% increase in vaccine availability when doubling transport frequency to the district level and 18% when tripling). In fact, relieving all stationary storage constraints could only increase vaccine availability by 11%, whereas doubling the transport frequency throughout the system led to a 26% increase and tripling the frequency led to a 30% increase. Increasing transport frequency also reduced the amount of stationary storage space needed in the supply chain. The supply chain required an additional 61,269L of storage to relieve constraints with the current transport frequency, 55,255L with transport frequency doubled, and 51,791L with transport frequency tripled. When evaluating vaccine supply chains, it is important to understand the interplay between stationary storage and transport. The HERMES-generated dynamic simulation model showed how augmenting transport can result in greater gains than only augmenting stationary storage and can reduce stationary storage needs.

  4. Salt dissolution sinkhole at the Weeks Island, Louisiana, Strategic Petroleum Reserve storage site

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Neal, J.T.; Myers, R.E.

    1994-12-31

    A sinkhole was first observed in May 1992 over the outer edge of the two-tiered former salt mine that was converted for oil storage by the US Strategic Petroleum Reserve (SPR). Results of diagnostic studies which included geophysical, geochemical, drilling, and hydrological methods suggest a direct connection exists between the surface collapse area and the underground mine. The connection was confirmed by correlative measurements of sediment slump rates, piezometric surface deflection, and brine influx rates into the mine. The dissolution of salt below the sinkhole that initiated the leak into the mine was likely caused by several confluent geologic processes,more » and exacerbated by mining-induced stresses that created fractures which severed as hydrologic flowpaths. Modeling studies of mine stresses show that years of tensional stresses may be required before cracking begins to occur, but once begun can continue to develop, and relieve the stress in that specific regime. The crack regime creates the avenue for incursion of groundwater, very slowly initially, but gradually enlarging as undersaturated groundwater dissolves salt on the sides of the crack. Mitigative measures include increasing the mine pressurization, slowing the dissolution by injecting brine into the sinkhole throat, and permeation grouting in hydrologic flowpaths.« less

  5. Management of diabetic complications: a chemical constituents based approach.

    PubMed

    Singh, Randhir; Kaur, Navpreet; Kishore, Lalit; Gupta, Girish Kumar

    2013-10-28

    Long term hyperglycemia leads to development of complications associated with diabetes. Diabetic complications are now a global health problem without effective therapeutic approach. Hyperglycemia and oxidative stress are important components for the development of diabetic complications. Over the past few decades, herbal medicines have attracted much attention as potential therapeutic agents in the prevention and treatment of diabetic complications due to their multiple targets and less toxic side effects. This review aims to assess the current available knowledge of medicinal herbs for attenuation and management of diabetic complications and their underlying mechanisms. Bibliographic investigation was carried out by scrutinizing classical text books and peer reviewed papers, consulting worldwide accepted scientific databases (SCOPUS, PUBMED, SCIELO, NISCAIR, Google Scholar) to retrieve available published literature. The inclusion criteria for the selection of plants were based upon all medicinal herbs and their active compounds with attributed potentials in relieving diabetic complications. Moreover, plants which have potential effect in ameliorating oxidative stress in diabetic animals have been included. Overall, 238 articles were reviewed for plant literature and out of the reviewed literature, 127 articles were selected for the study. Various medicinal plants/plant extracts containing flavonoids, alkaloids, phenolic compounds, terpenoids, saponins and phytosterol type chemical constituents were found to be effective in the management of diabetic complications. This effect might be attributed to amelioration of persistent hyperglycemia, oxidative stress and modulation of various metabolic pathways involved in the pathogenesis of diabetic complications. Screening chemical candidate from herbal medicine might be a promising approach for new drug discovery to treat the diabetic complications. There is still a dire need to explore the mechanism of action of various plant extracts and their toxicity profile and to determine their role in therapy of diabetic complications. Moreover, a perfect rodent model which completely mimics human diabetic complications should be developed. © 2013 Elsevier Ireland Ltd. All rights reserved.

  6. Woody plants of North America [product review

    Treesearch

    Don C. Bragg; Hope A. Bragg

    2001-01-01

    The authors review a 2-CD set created to aid in identifying woody plants. The product is intended to supplement (rather than replace) field instruction for identifying 470 of the most common native and introduced trees and shrubs in North America.

  7. Invite Wildlife to Your Backyard

    ERIC Educational Resources Information Center

    Thomas, Jack Ward; And Others

    1973-01-01

    A step-by-step plan to create a wildlife habitat around one's home is depicted. Three stages, covering 30 to 40 years from initial planting, will provide food, water, cover, and reproductive areas for a large variety of plant and animal life. (BL)

  8. Providing Campus Environmental Coherence by Landscaping.

    ERIC Educational Resources Information Center

    Pawsey, Maurice R.

    1982-01-01

    A landscaping approach aimed at integrating greatly contrasting building types and materials resulting from unplanned growth used these elements to create design continuity; paving, planting, landscape furniture, planting and lawn protection, signs, lights, placement of posters and notices, and bicycle racks. (MSE)

  9. Scenario Analysis of the Impact on Drinking Water Intakes from Bromide in the Discharge of Treated Oil and Gas Wastewater

    EPA Pesticide Factsheets

    EPA scientists created different scenarios for conventional commercial wastewater treatment plants that treat oil and gas wastewaters to evaluate the impact from bromide in discharges by the CWTP plants.

  10. Pubectomy and stereotactic radiotherapy for the treatment of a non-resectable sacral osteosarcoma causing pelvic canal obstruction in a dog

    PubMed Central

    Randall, Victoria D.; Boston, Sarah E.; Gardner, Heather L.; Griffin, Lynn; Oblak, Michelle L.; Kubicek, Lyndsay

    2016-01-01

    A pubectomy was carried out to relieve obstruction of the pelvic canal in a 6-year-old dog diagnosed with sacral osteosarcoma. Two days after surgery, the dog was ambulatory with normal urination and defecation. Pubectomy is a viable option to relieve clinical signs in patients with pelvic canal obstruction due to a non-resectable tumor. PMID:27587885

  11. Analysis of Random Drop for Gateway Congestion Control

    DTIC Science & Technology

    1989-11-01

    effective congest)on control policies. Currently No Gateway Policy is used to relieve and signal congestion, which leads to unfair service to the...early application of the policy removes the pressure of congestion relief and allows more accurate signaling of congestion. ’ To be used effectively ...prompted the need for more effective congestion control policies. Currently No Gateway Policy is used to relieve and signal congestion, which leads to

  12. Monitoring Million Trees LA: Tree performance during the early years and future benefits

    Treesearch

    E. Gregory McPherson

    2014-01-01

    Million Trees LA (MTLA) is one of several large-scale mayoral tree planting initiatives striving to create more livable cities through urban forestry. This study combined field sampling of tree survival and growth with numerical modeling of future benefits to assess performance of MTLA plantings. From 2006 to 2010 MTLA planted a diverse mix of 91,786 trees....

  13. Contributions of gopher mound and casting disturbances to plant community structure in a Cascade Range meadow complex

    Treesearch

    M. Case; C.B. Halpern; S.A. Levin

    2013-01-01

    Pocket gophers (Geomyidae) are major agents of disturbance in North American grasslands. Gopher mounds bury existing plants and influence community structure through various mechanisms. However, in mountain meadows that experience winter snowpack, gophers also create winter castings, smaller tube-shaped deposits, previously ignored in studies of plant–gopher...

  14. The indirect impact of long-term overbrowsing on insects in the Allegheny National Forest region of Pennsylvania

    Treesearch

    Michael J. Chips; Ellen H. Yerger; Arpad Hervanek; Tim Nuttle; Alex Royo; Jonathan N. Pruitt; Terrence P. McGlynn; Cynthia L. Riggall; Walter P. Carson

    2015-01-01

    Overbrowsing has created depauperate plant communities throughout the eastern deciduous forest. We hypothesized these low-diversity plant communities are associated with lower insect diversity. We compared insects inside and outside a 60-year-old fenced deer exclosure where plant species richness is 5x higher inside versus outside. We sampled aboveground and litter...

  15. Canopy gap size influences niche partitioning of the ground-layer plant community in a northern temperate forest

    Treesearch

    Christel C. Kern; Rebecca A. Montgomery; Peter B. Reich; Terry F. Strong

    2013-01-01

    The Gap Partitioning Hypothesis (GPH) posits that gaps create heterogeneity in resources crucial for tree regeneration in closed-canopy forests, allowing trees with contrasting strategies to coexist along resource gradients. Few studies have examined gap partitioning of temperate, ground-layer vascular plants. We used a ground-layer plant community of a temperate...

  16. Using Landsat Thematic Mapper and SPOT Satellite Imagery to inventory wetland plants of the Coeur d'Alene Floodplain

    Treesearch

    F. M. Roberts; P. E. Gessler

    2000-01-01

    Landsat Thematic Mapper (TM) and SPOT Satellite Imagery were used to map wetland plant species in thc Coeur d'Alene floodplain in northern Idaho. This paper discusses the methodology used to create a wetland plant species map for the floodplain. Species mapped included common cattail (Typha latifolia); water horse-tail (Equisetum...

  17. 77 FR 3423 - Endangered and Threatened Wildlife and Plants; 90-Day Finding on a Petition To List the `I'iwi as...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-24

    ... vegetation, eliminate food plants for birds, create mosquito breeding sites, open the forest floor to weed...-0110; 4500030114] Endangered and Threatened Wildlife and Plants; 90-Day Finding on a Petition To List... warranted. To ensure that this status review is comprehensive, we are requesting scientific and commercial...

  18. Market perceptions and opportunities for native plant production on the southern Colorado Plateau

    Treesearch

    Donna L. Peppin; Peter Z. Fule; Janet C. Lynn; Anne L. Mottek-Lucas; Carolyn Hull Sieg

    2010-01-01

    Increases in revegetation activities have created a large demand for locally adapted native plant materials (NPM) in the southwestern United States. Currently, there is a minimal supply of local genotypes to meet this demand. We investigated the potential for the initiation of a native plant market in the southern Colorado Plateau. Through a literature search,...

  19. Effects of Competing Narratives on Public Perceptions of Opioid Pain Reliever Addiction during Pregnancy.

    PubMed

    Kennedy-Hendricks, Alene; McGinty, Emma E; Barry, Colleen L

    2016-10-01

    Opioid pain reliever addiction has increased among women of reproductive age over the last fifteen years. News media and public attention have focused on the implications of this trend for infants exposed to opioids prenatally, with state policy responses varying in the extent to which they are punitive or public health oriented. We fielded a six-group randomized experiment among a nationally representative sample of US adults to test the effects of narratives portraying a woman with opioid pain reliever addiction during pregnancy on beliefs about people addicted to opioid pain relievers, perceptions of treatment effectiveness, policy attitudes, and emotional responses. Portraying a high socioeconomic status (SES) woman in the narrative lowered perceptions of individual blame for addiction and reduced public support for punitive policies. Depicting the barriers to treatment faced by a low SES woman lowered support for punitive policies and increased support for expanded insurance coverage for treatment. The extent to which narratives portraying successfully treated addiction affected public attitudes depended on the SES of the woman portrayed. These findings can inform the development of communication strategies to reduce stigma toward this population, reduce support for punitive policies, and increase support for more public health-oriented approaches to addressing this problem. Copyright © 2016 by Duke University Press.

  20. Well-Loved Music Robustly Relieves Pain: A Randomized, Controlled Trial

    PubMed Central

    Hsieh, Christine; Kong, Jian; Kirsch, Irving; Edwards, Robert R.; Jensen, Karin B.; Kaptchuk, Ted J.; Gollub, Randy L.

    2014-01-01

    Music has pain-relieving effects, but its mechanisms remain unclear. We sought to verify previously studied analgesic components and further elucidate the underpinnings of music analgesia. Using a well-characterized conditioning-enhanced placebo model, we examined whether boosting expectations would enhance or interfere with analgesia from strongly preferred music. A two-session experiment was performed with 48 healthy, pain experiment-naïve participants. In a first cohort, 36 were randomized into 3 treatment groups, including music enhanced with positive expectancy, non-musical sound enhanced with positive expectancy, and no expectancy enhancement. A separate replication cohort of 12 participants received only expectancy-enhanced music following the main experiment to verify the results of expectancy-manipulation on music. Primary outcome measures included the change in subjective pain ratings to calibrated experimental noxious heat stimuli, as well as changes in treatment expectations. Without conditioning, expectations were strongly in favor of music compared to non-musical sound. While measured expectations were enhanced by conditioning, this failed to affect either music or sound analgesia significantly. Strongly preferred music on its own was as pain relieving as conditioning-enhanced strongly preferred music, and more analgesic than enhanced sound. Our results demonstrate the pain-relieving power of personal music even over enhanced expectations. Trial Information Clinicaltrials.gov NCT01835275. PMID:25211164

  1. Artificial pneumothorax: a safe and simple method to relieve pain during microwave ablation of subpleural lung malignancy.

    PubMed

    Hou, Xiaowei; Zhuang, Xingjun; Zhang, Haiwen; Wang, Kai; Zhang, Yuanxin

    2017-08-01

    Microwave ablation has been extensively used for eliminating pulmonary tumors; however, it is usually associated with severe pain under local anesthesia. Decreasing the power and shortening the ablation time can help to relieve the pain; however, this leads to incomplete ablation and an increasing recurrence rate. This research aims to employ an artificial pneumothorax to increase both the curative effect and pain relief during the ablation procedure. From July 2013 to January 2015, nine patients presenting with 10 subpleural lung tumors (age: 44-78 years) with a high possibility of severe pain underwent the artificial pneumothorax during microwave ablation. The pain assessment scores and complications induced by the artificial pneumothorax were recorded and analyzed by a CT scan follow-up. The tumors of the nine patients were eliminated successfully using microwave ablation with artificial pneumothorax under local anesthesia. The pain caused by the ablation was relieved to a great extent with an average rate of 94.66% (range: 63.3%-100%) and all tumors were ablated completely. No severe complications occurred after the operation. The artificial pneumothorax is a reliable therapy to improve the curative effect of microwave ablation under local anesthesia by relieving the pain of the patients.

  2. Multicenter comparison of the efficacy on prevention of pressure ulcer in postoperative patients between two types of pressure-relieving mattresses in China

    PubMed Central

    Jiang, Qixia; Li, Xiaohua; Zhang, Aiqin; Guo, Yanxia; Liu, Yahong; Liu, Haiying; Qu, Xiaolong; Zhu, Yajun; Guo, Xiujun; Liu, Li; Zhang, Liyan; Bo, Suping; Jia, Jing; Chen, Yuejuan; Zhang, Rui; Wang, Jiandong

    2014-01-01

    Objective: Present study is designed to evaluate the effects of preventing pressure ulcer in surgical patients with two types of pressure-relieving mattresses. Methods: 1074 surgical patients from 12 hospitals in China were divided into A group (static air mattress with repositioning every 2 hours, n = 562) and B group (power pressure air mattress with repositioning every 2 hours, n = 512). The patient was subjected to a pressure-relieving mattress and observed from 0-5 days after surgery. Indications include the Braden scores, hospital-acquired pressure ulcers (HAPU) incidence and stage. Results: The Braden scores between two groups in five days after surgery were no significant (P > 0.05). The incidence of HAPU between two groups in same days also was no significant (1.07% vs. 0.98%, P > 0.05). The incidence of Stage I and stage II pressure ulcers in group A and B were 1.07% (6/562) and 0.98% (5/512), respectively (χ2 = 0.148, P = 0.882). Conclusion: The effects of preventing pressure ulcer in surgical patients with two types of pressure-relieving mattresses are similar, but the protocol by static air mattress with repositioning every 2 hours is benefit when no power. PMID:25356144

  3. Vegetation community composition in wetlands created following oil sand mining in Alberta, Canada.

    PubMed

    Roy, Marie-Claude; Foote, Lee; Ciborowski, Jan J H

    2016-05-01

    Reclaiming wetlands following open pit mining for industrial oil sand extraction is challenging due to the physical and chemical conditions of the post-mined landscape. The aim of our study was to examine and compare the influence of oil sands process water (OSPW) and material (fine fluid tails or FFT) on the plant community composition of created wetlands. Compared to created-unamended and natural wetlands, the created wetlands amended with OSPW and/or FFT (created-tailings wetlands) had significantly higher water salinity, conductivity, dissolved oxygen concentration and lower oxidative-reductive potential. Water chemistry parameters of created-unamended did not differ significantly from those of natural wetlands. The sediment of created wetlands had significantly less moisture, total nitrogen, and organic content than the natural wetlands. The application of OSPW/FFT in created wetlands will likely lead to initial vegetation composition atypical of natural regional wetlands. For the objective of reclaiming vegetation composition to the status of natural regional wetlands, unamended wetlands were the best reclamation option, based on the physical and chemical parameters measured. Despite being the favored reclamation option, created-unamended wetlands' physical and chemical characteristics remain atypical of natural wetlands. Most significantly, the basin morphometry of created wetlands was significantly different from that of naturally-formed wetlands in the region, and this appears to partly explain difference in vegetation composition. We also demonstrate that species richness alone is not a useful measure in wetland monitoring. Instead, plant community composition is a better indicator of wetland conditions. Copyright © 2016 Elsevier Ltd. All rights reserved.

  4. Using heat pipe to make isotherm condition in catalytic converters of sulfuric acid plants

    NASA Astrophysics Data System (ADS)

    Yousefi, M.; Pahlavanzadeh, H.; Sadrameli, S. M.

    2017-08-01

    In this study, for the first time, it is tried to construct a pilot reactor, for surveying the possibility of creating isothermal condition in the catalytic convertors where SO2 is converted to SO3 in the sulfuric acid plants by heat pipe. The thermodynamic and thermo-kinetic conditions were considered the same as the sulfuric acid plants converters. Also, influence of SO2 gas flow rate on isothermal condition, has been studied. A thermo-siphon type heat pipe contains the sulfur + 5% iodine as working fluid, was used for disposing the heat of reaction from catalytic bed. Our results show that due to very high energy-efficiency, isothermal and passive heat transfer mechanism of heat pipe, it is possible to reach more than 95% conversion in one isothermal catalytic bed. As the results, heat pipe can be used as a certain piece of equipment to create isothermal condition in catalytic convertors of sulphuric acid plants. With this work a major evaluation in design of sulphuric acid plants can be taken place.

  5. Creation of reference DNA barcode library and authentication of medicinal plant raw drugs used in Ayurvedic medicine.

    PubMed

    Vassou, Sophie Lorraine; Nithaniyal, Stalin; Raju, Balaji; Parani, Madasamy

    2016-07-18

    Ayurveda is a system of traditional medicine that originated in ancient India, and it is still in practice. Medicinal plants are the backbone of Ayurveda, which heavily relies on the plant-derived therapeutics. While Ayurveda is becoming more popular in several countries throughout the World, lack of authenticated medicinal plant raw drugs is a growing concern. Our aim was to DNA barcode the medicinal plants that are listed in the Ayurvedic Pharmacopoeia of India (API) to create a reference DNA barcode library, and to use the same to authenticate the raw drugs that are sold in markets. We have DNA barcoded 347 medicinal plants using rbcL marker, and curated rbcL DNA barcodes for 27 medicinal plants from public databases. These sequences were used to create Ayurvedic Pharmacopoeia of India - Reference DNA Barcode Library (API-RDBL). This library was used to authenticate 100 medicinal plant raw drugs, which were in the form of powders (82) and seeds (18). Ayurvedic Pharmacopoeia of India - Reference DNA Barcode Library (API-RDBL) was created with high quality and authentic rbcL barcodes for 374 out of the 395 medicinal plants that are included in the API. The rbcL DNA barcode differentiated 319 species (85 %) with the pairwise divergence ranging between 0.2 and 29.9 %. PCR amplification and DNA sequencing success rate of rbcL marker was 100 % even for the poorly preserved medicinal plant raw drugs that were collected from local markets. DNA barcoding revealed that only 79 % raw drugs were authentic, and the remaining 21 % samples were adulterated. Further, adulteration was found to be much higher with powders (ca. 25 %) when compared to seeds (ca. 5 %). The present study demonstrated the utility of DNA barcoding in authenticating medicinal plant raw drugs, and found that approximately one fifth of the market samples were adulterated. Powdered raw drugs, which are very difficult to be identified by taxonomists as well as common people, seem to be the easy target for adulteration. Developing a quality control protocol for medicinal plant raw drugs by incorporating DNA barcoding as a component is essential to ensure safety to the consumers.

  6. Broadening the U.S. alfalfa germplasm base

    USDA-ARS?s Scientific Manuscript database

    Over 4000 alfalfa (Medicago sativa L.) plant introductions (PIs) exist in the USDA-ARS National Plant Germplasm System (NPGS). NAAIC has discussed/proposed pre-breeding efforts to utilize this germplasm for creating pre-commercial alfalfa germplasm. Funding constraints have been one impediment to th...

  7. Large-Eddy Simulation of Wind-Plant Aerodynamics

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Churchfield, M. J.; Lee, S.; Moriarty, P. J.

    In this work, we present results of a large-eddy simulation of the 48 multi-megawatt turbines composing the Lillgrund wind plant. Turbulent inflow wind is created by performing an atmospheric boundary layer precursor simulation, and turbines are modeled using a rotating, variable-speed actuator line representation. The motivation for this work is that few others have done large-eddy simulations of wind plants with a substantial number of turbines, and the methods for carrying out the simulations are varied. We wish to draw upon the strengths of the existing simulations and our growing atmospheric large-eddy simulation capability to create a sound methodology formore » performing this type of simulation. We used the OpenFOAM CFD toolbox to create our solver. The simulated time-averaged power production of the turbines in the plant agrees well with field observations, except with the sixth turbine and beyond in each wind-aligned. The power produced by each of those turbines is overpredicted by 25-40%. A direct comparison between simulated and field data is difficult because we simulate one wind direction with a speed and turbulence intensity characteristic of Lillgrund, but the field observations were taken over a year of varying conditions. The simulation shows the significant 60-70% decrease in the performance of the turbines behind the front row in this plant that has a spacing of 4.3 rotor diameters in this direction. The overall plant efficiency is well predicted. This work shows the importance of using local grid refinement to simultaneously capture the meter-scale details of the turbine wake and the kilometer-scale turbulent atmospheric structures. Although this work illustrates the power of large-eddy simulation in producing a time-accurate solution, it required about one million processor-hours, showing the significant cost of large-eddy simulation.« less

  8. Pharmacological Review on Centella asiatica: A Potential Herbal Cure-all

    PubMed Central

    Gohil, Kashmira J.; Patel, Jagruti A.; Gajjar, Anuradha K.

    2010-01-01

    In recent times, focus on plant research has increased all over the world. Centella asiatica is an important medicinal herb that is widely used in the orient and is becoming popular in the West. Triterpenoid, saponins, the primary constituents of Centella asiatica are manly believed to be responsible for its wide therapeutic actions. Apart from wound healing, the herb is recommended for the treatment of various skin conditions such as leprosy, lupus, varicose ulcers, eczema, psoriasis, diarrhoea, fever, amenorrhea, diseases of the female genitourinary tract and also for relieving anxiety and improving cognition. The present review attempts to provide comprehensive information on pharmacology, mechanisms of action, various preclinical and clinical studies, safety precautions and current research prospects of the herb. At the same time, studies to evaluate the likelihood of interactions with drugs and herbs on simultaneous use, which is imperative for optimal and safe utilization of the herb, are discussed. PMID:21694984

  9. [Marijuana for medical purposes--public health perspective].

    PubMed

    Gazdek, Davorka

    2014-01-01

    Studies show significant negative effects of smoking marijuana on physical and mental health as well as social and occupational functioning. At the same time, there are more considerations about its ability to treat a number of diseases. This review summarizes current data in scientific literature that examines the medical effects of marijuana on human health with particular emphasis on its potential in medicine. Marijuana has a range of adverse health effects, particularly relating to young people because of higher risk for psychosis, traffic accidents, and cognitive impairment. Marijuana may be helpful in relieving symptoms of nausea and vomiting, increasing appetite and pain relief for persons with cancer, AIDS and multiple sclerosis. Smoking marijuana can impose significant public health risks. If there is a medical role for using marijuana, it lies in the application of clearly defined medical protocols and chemically defined compounds, not with using the unprocessed cannabis plant.

  10. Synthesis of o,p-EDDHA and its detection as the main impurity in o,o-EDDHA commercial iron chelates.

    PubMed

    Gómez-Gallego, Mar; Sierra, Miguel A; Alcázar, Roberto; Ramírez, Pedro; Piñar, Carmen; Mancheño, María José; García-Marco, Sonia; Yunta, Felipe; Lucena, Juan José

    2002-10-23

    Ethylenediamine-N,N'bis(o-hydroxyphenyl)acetic acid (o,o-EDDHA) is one of the most efficient iron chelates employed to relieve iron chlorosis in plants. However, the presence of positional isomers of EDDHA in commercial iron chelates has been recently demonstrated, and among them, it has been claimed that ethylenediamine-N(o-hydroxyphenylacetic)-N'(p-hydroxyphenylacetic) acid (o,p-EDDHA) is the main impurity present in EDDHA fertilizers. Here we report the preparation of o,p-EDDHA, a compound whose synthesis had not been previously reported. The synthetic o,p-EDDHA is able to form ferric complexes, and it has been used as a standard in the analysis of the impurities of commercial iron fertilizers. The presence of o,p-EDDHA/Fe(3+) in commercial samples has been unambiguously demonstrated by HPLC.

  11. Solving nuts-and-bolts nuclear problems

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Olmstead, A.; Schoen, J.

    1979-05-01

    The Operations and Maintenance Information Service (MIS), created and operated by NUS Corp., was designed to improve plant availability through the exchange of practical information between nuclear plants and a return to an emphasis on the problem-solving process. MIS meetings cover a range of plant problems and have been unique in bringing the rapid feedback of information pertinent to the day-to-day working operation of a total plant. Much of the response is by telephone contact, although the monthly newsletter, semi-annual meetings, and scheduled plant visits are also helpful.

  12. Improvement of the soil nitrogen content and maize growth by earthworms and arbuscular mycorrhizal fungi in soils polluted by oxytetracycline.

    PubMed

    Cao, Jia; Wang, Chong; Ji, Dingge

    2016-11-15

    Interactions between earthworms (Eisenia fetida) and arbuscular mycorrhizal fungi (Rhizophagus intraradices, AM fungi) have been suggested to improve the maize nitrogen (N) content and biomass and were studied in soils polluted by oxytetracycline (OTC). Maize was planted and amended with AMF and/or earthworms (E) in the soil with low (1mgkg(-1) soil DM) or high (100mgkg(-1) soil DM) amounts of OTC pollution in comparison to soil without OTC. The root colonization, shoot and root biomass, shoot and root N contents, soil nitrogen forms, ammonia-oxidizing bacteria (AOB) and archaea (AOA) were measured at harvest. The results indicated that OTC decreased maize shoot and root biomass (p<0.05) by mediating the soil urease activity and AOB and AOA abundance, which resulted in a lower N availability for maize roots and shoots. There was a significant interaction between earthworms and AM fungi on the urease activity in soil polluted by OTC (p<0.05). Adding earthworms or AM fungi could increase the maize biomass and N content (p<0.05) in OTC polluted soil by increasing the urease activity and relieving the stress from OTC on the soil N cycle. AM fungi and earthworms interactively increased maize shoot and root biomass (p<0.05) in the OTC polluted soils through their regulation of the urease activity and the abundance of ammonia oxidizers, resulting in different soil NH4(+)-N and NO3(-)-N contents, which may contribute to the N content of maize shoots and roots. Earthworms and AM fungi could be used as an efficient method to relieve the OTC stress in agro-ecosystems. Copyright © 2016 Elsevier B.V. All rights reserved.

  13. Opposing Control by Transcription Factors MYB61 and MYB3 Increases Freezing Tolerance by Relieving C-Repeat Binding Factor Suppression1[OPEN

    PubMed Central

    Zhang, Yunqin; Miao, Zhenyan; Xie, Can; Meng, Xiangzhao; Deng, Jie; Mysore, Kirankumar S.; Frugier, Florian; Wang, Tao

    2016-01-01

    Cold acclimation is an important process by which plants respond to low temperature and enhance their winter hardiness. C-REPEAT BINDING FACTOR1 (CBF1), CBF2, and CBF3 genes were shown previously to participate in cold acclimation in Medicago truncatula. In addition, MtCBF4 is transcriptionally induced by salt, drought, and cold stresses. We show here that MtCBF4, shown previously to enhance drought and salt tolerance, also positively regulates cold acclimation and freezing tolerance. To identify molecular factors acting upstream and downstream of the MtCBF4 transcription factor (TF) in cold responses, we first identified genes that are differentially regulated upon MtCBF4 overexpression using RNAseq Digital Gene Expression Profiling. Among these, we showed that MtCBF4 directly activates the transcription of the COLD ACCLIMATION SPECIFIC15 (MtCAS15) gene. To gain insights into how MtCBF4 is transcriptionally regulated in response to cold, an R2R3-MYB TF, MtMYB3, was identified based on a yeast one-hybrid screen as binding directly to MYB cis-elements in the MtCBF4 promoter, leading to the inhibition of MtCBF4 expression. In addition, another MYB TF, MtMYB61, identified as an interactor of MtMYB3, can relieve the inhibitory effect of MtMYB3 on MtCBF4 transcription. This study, therefore, supports a model describing how MtCBF4 is regulated by antagonistic MtMYB3/MtMYB61 TFs, leading to the up-regulation of downstream targets such as MtCAS15 acting in cold acclimation in M. truncatula. PMID:27578551

  14. Effect of an orally formulated processed black cumin, from Iranian traditional medicine pharmacopoeia, in relieving symptoms of knee osteoarthritis: A prospective, randomized, double-blind and placebo-controlled clinical trial.

    PubMed

    Salimzadeh, Ahmad; Ghourchian, Anahita; Choopani, Rasool; Hajimehdipoor, Homa; Kamalinejad, Mohammad; Abolhasani, Maryam

    2017-06-01

    Osteoarthritis is a global health problem, especially for the elderly. A good replacement for non-surgical treatments is the use of traditional medicines. We selected a revere plant (Nigella sativa L.), a widely utilized medicinal herb for the treatment of inflammatory conditions, from the Iranian traditional medicine (ITM) pharmacopoeia with proven anti-inflammatory and analgesic actions. We performed a prospective, randomized, double-blind, and placebo-controlled clinical trial, in order to investigate whether the herb is useful in alleviating the symptoms of knee osteoarthritis. American College of Rheumatology clinical criteria were the basis of diagnosis, while the Knee injury and Osteoarthritis Outcome Score (KOOS) questionnaire was considered as the main outcome measure. One hundred and ten eligible patients were assigned to receive a placebo or an active intervention (2 g/day of processed N. sativa seed powder in divided doses). Acetaminophen tablets were the rescue medicine. Finally, 40 patients in the placebo group and 37 patients in the active group completed the trial and were included in the statistical analysis. Both cohorts demonstrated statistically significant within-group differences (P < 0.05) in some subscales that were more prominent in the active group without any considerable adverse effects. Nevertheless, KOOS score results and the mean number of acetaminophen tablets used by patients showed no statistically significant between-group differences. It can be concluded that future programmed studies with larger sample sizes, longer follow-up periods, and other forms of N. sativa seeds as an active intervention is necessary to evaluate its efficacy in relieving the symptoms of knee osteoarthritis. © 2017 Asia Pacific League of Associations for Rheumatology and John Wiley & Sons Australia, Ltd.

  15. Cytosolic Glutamine Synthetase Gln1;2 Is the Main Isozyme Contributing to GS1 Activity and Can Be Up-Regulated to Relieve Ammonium Toxicity1[OPEN

    PubMed Central

    Pedersen, Carsten

    2016-01-01

    Cytosolic GS1 (Gln synthetase) is central for ammonium assimilation in plants. High ammonium treatment enhanced the expression of the GS1 isogene Gln-1;2 encoding a low-affinity high-capacity GS1 protein in Arabidopsis (Arabidopsis thaliana) shoots. Under the same conditions, the expression of the high-affinity low-capacity isoform Gln-1;1 was reduced. The expression of Gln-1;3 did not respond to ammonium treatment while Gln-1;4 and Gln-1;5 isogenes in all cases were expressed at a very low level. Gln-2 was highly expressed in shoots but only at a very low level in roots. To investigate the specific functions of the two isogenes Gln-1;1 and Gln-1;2 in shoots for ammonium detoxification, single and double knock-out mutants were grown under standard N supply or with high ammonium provision. Phenotypes of the single mutant gln1;1 were similar to the wild type, while growth of the gln1;2 single mutant and the gln1;1:gln1;2 double mutant was significantly impaired irrespective of N regime. GS1 activity was significantly reduced in both gln1;2 and gln1;1:gln1;2. Along with this, the ammonium content increased while that of Gln decreased, showing that Gln-1;2 was essential for ammonium assimilation and amino acid synthesis. We conclude that Gln-1;2 is the main isozyme contributing to shoot GS1 activity in vegetative growth stages and can be up-regulated to relieve ammonium toxicity. This reveals, to our knowledge, a novel shoot function of Gln-1;2 in Arabidopsis shoots. PMID:27231101

  16. n-Hexane intoxication in a Chinese medicine pharmaceutical plant: a case report.

    PubMed

    Pan, Jo-Hui; Peng, Chiung-Yu; Lo, Chung-Ting; Dai, Chia-Yen; Wang, Chao-Ling; Chuang, Hung-Yi

    2017-04-28

    n-Hexane is a well-known neurotoxicant. Polyneuropathy due to occupational n-hexane exposure has been reported worldwide, however, our case is the first report in the Chinese herb industry. A 25-year-old Asian man experienced progressive weakness and numbness in his hands and feet after working as an operator in a Chinese medicine pharmaceutical plant for the manufacture of Chinese herbal pain relief patches for 10 months. Electrophysiological studies indicated a reduction in nerve conduction velocity, prolongation of distal latencies, mildly positive sharp waves, and reduced recruitment with polyphasic potentials, particularly at distal sites. Demyelination with axonal degeneration caused by occupational n-hexane exposure was strongly suspected. Through investigation of our patient's workplace, the ambient n-hexane concentration in air was found to considerably exceed the permissible exposure limit/time-weighted average for n-hexane in Taiwan. His symptoms were gradually relieved after 4 months of cessation of exposure to n-hexane. He was then confirmed as a case of occupational n-hexane intoxication. Further effective control measures should be implemented as soon as possible to prevent exposure of workers to n-hexane. Despite a typical clinical presentation, his exposure at workplace was appropriately investigated. Chemical exposure in Chinese medicine pharmaceutical plants could be an emerging issue that may affect workers' health. The lack of knowledge and management of solvents could endanger the health of workers. This case has profound educational implications for occupational health and is worthy of further follow-up for improving hazards control.

  17. A potential of some medicinal plants as an antiulcer agents.

    PubMed

    Gadekar, R; Singour, P K; Chaurasiya, P K; Pawar, R S; Patil, U K

    2010-07-01

    Peptic ulcers are a broad term that includes ulcers of digestive tract in the stomach or the duodenum. The formation of peptic ulcers depends on the presence of acid and peptic activity in gastric juice plus a breakdown in mucosal defenses. There are two major factors that can disrupt the mucosal resistance to injury: non-steroidal antiinflammatory drugs (NSAIDs) example, aspirin and Helicobacter pylori infection. Numerous natural products have been evaluated as therapeutics for the treatment of a variety of diseases, including peptic ulcer. There has been considerable pharmacological investigation into the antiulcer activity of some compounds. In this work, we shall review the literature on different medicinal plant and alkaloids with antiulcer activity. This article reviews the antiacid/anti-peptic, gastroprotective and/or antiulcer properties of the most commonly employed herbal medicines and their identified active constituents. The experimental parameters used for antiulcer activity were cold restraint stress-induced ulcer model, Diclofenac-induced ulcer model in rats, (HCl-ethanol)-induced ulcer in mice and water immersion stress-induced ulcer in rats. The ideal aims of treatment of peptic ulcer disease are to relieve pain, heal the ulcer and delay ulcer recurrence. About 70% of patients with peptic ulcer disease are infected by Helicobacter pylori and eradication of this microorganism seems to be curative for this disease. This article reviews drugs derived from medicinal plant more commonly used in the world for peptic ulcer and, if reported, the antiulcer activity. This article will be concerned only with the antiulcer and gastro-protective effects.

  18. Rethinking Suffering: Allowing for Suffering that is Intrinsic at End of Life.

    PubMed

    Rattner, Maxxine; Berzoff, Joan

    2016-01-01

    The dilemma so central to the work of providers of palliative and end-of-life care is the paradox of their professional and ethical duty to try to relieve suffering and the limitations of so doing. While the capacity to sit with suffering at the end of life is critical to clinical work, the idea that some intrinsic suffering cannot necessarily always be relieved may model for patients and families that suffering can be borne. Clinicians who encounter unrelievable suffering may feel a sense of failure, helplessness, moral distress, and compassion fatigue. While tolerating suffering runs counter to the aims of palliative care, acknowledging it, bearing it, and validating it may actually help patients and families to do the same. "Sitting with suffering" signals a paradigm shift within the discipline of palliative care, as it asks clinicians to rethink their role in being able to relieve some forms of psychosocial suffering intrinsic to dying.

  19. Clinical hypnosis for palliative care in severe chronic diseases: a review and the procedures for relieving physical, psychological and spiritual symptoms.

    PubMed

    Brugnoli, Maria Paola

    2016-10-01

    Hypnotic treatment in severe chronic diseases, for pain and symptoms relief, has proven efficacy as adjuvant therapy, and should be offered to any individual, who expresses an interest in this method. While some theorize hypnotizability as a changing attribute of the individual, there is a growing body of literature that indicates hypnotizability may be characterized as a constellation of potentially modifiable attitudes and skills, which are strongly influenced by related factors, as suffering, in severe chronic diseases. In this article, I briefly review representative studies recognizing how clinical hypnosis in medicine is an effective complementary therapy, for pain and symptom's relief in severe chronic diseases and in palliative care. This paper highlights: (I) a scientific review to underline how clinical hypnosis has an important impact on the treatment goals and integration in relieving pain and symptoms; (II) the advanced techniques for effectively relieving pain and symptoms.

  20. Gene evolutionary trajectories and GC patterns driven by recombination in Zea mays

    USDA-ARS?s Scientific Manuscript database

    Recombination occurring during meiosis is critical for creating genetic variation and plays an essential role in plant evolution. In addition to creating novel gene combinations, recombination can affect genome structure through altering GC patterns. In maize (Zea mays) and other grasses, another in...

  1. Environmental Life Cycle Assessment and Cost Analysis of Bath, NY Wastewater Treatment Plant: Potential Upgrade Implications

    EPA Science Inventory

    Many communities across the U.S. are required to upgrade wastewater treatment plants (WWTP) to meet increasingly stringent nutrient effluent standards. However, increased capital, energy and chemical requirements of upgrades create potential trade-offs between eutrophication pot...

  2. 16. VIEW OF A ROLLING MILL THAT WAS USED TO ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    16. VIEW OF A ROLLING MILL THAT WAS USED TO CREATE A METAL SHEET (SHOWN). (4/16/57) - Rocky Flats Plant, Uranium Rolling & Forming Operations, Southeast section of plant, southeast quadrant of intersection of Central Avenue & Eighth Street, Golden, Jefferson County, CO

  3. Kenaf and bioremediation in Azerbaijan: Planting locations, plant populations, and varieties

    USDA-ARS?s Scientific Manuscript database

    Scientists, businesses, and the Azerbaijan government are bringing together two ancient natural resources, petroleum and kenaf (Hibiscus cannabinus L.), to create a balance between economic growth and environmental reclamation. Oil and kenaf have been used for over 3000 years. Although oil continu...

  4. Phenomic approaches and tools for phytopathologists

    USDA-ARS?s Scientific Manuscript database

    Plant phenomics approaches aim to evaluate traits such as growth, performance, and composition of plants using a suite of non-invasive technologies. The ultimate goal is to link phenotypic traits to the genetic information for particular genotypes, thus creating the bridge between the phenome and ge...

  5. Resource-use efficiencies of three indigenous tree species planted in resource islands created by shrubs: implications for reforestation of subtropical degraded shrublands

    Treesearch

    Nan Liu; Qinfeng Guo

    2012-01-01

    Shrub resource islands are characterized by resources accumulated shrubby areas surrounded by relative barren soils. This research aims to determine resource-use efficiency of native trees species planted on shrub resource islands, and to determine how the planted trees may influence the resource islands in degraded shrublands in South China. Shrub (Rhodomyrtus...

  6. A Manual for the Identification of Invasive Plants in Southern Forests

    Treesearch

    Lewis Zimmerman

    2012-01-01

    This manual was created specifically for use by the U.S. Forest Service Southern Research Station (SRS), Forest Inventory and Analysis (FIA) field survey crews. The SRS FIA unit currently collects data on 33 invasive plants or groups across 13 States. The ability to accurately identify plant species in the field is a crucial component of monitoring a species’ presence...

  7. Interactions of fire and nonnative species across an elevation/plant community gradient in Hawaii volcanoes national park

    Treesearch

    Alison Ainsworth; J. Boone Kauffman

    2010-01-01

    Invasive species interacting with fires pose a relatively unknown, but potentially serious, threat to the tropical forests of Hawaii. Fires may create conditions that facilitate species invasions, but the degree to which this occurs in different tropical plant communities has not been quantified. We documented the survival and establishment of plant species for 2 yr...

  8. The Woody Plant Seed Manual

    Treesearch

    Franklin T. Bonner; Robert P. Karrfalt

    2008-01-01

    The first comprehensive handbook on the seeds of trees and shrubs produced by the USDA Forest Service was USDA Misc. Pub. 654, Woody-Plant Seed Manual. The manuscript was ready for publication in 1941, but World War II delayed publication until 1948. The boom in tree planting in the 1950s and 1960s created a large demand for seeds and exposed the gaps in our knowledge...

  9. Novel Digital Features Discriminate Between Drought Resistant and Drought Sensitive Rice Under Controlled and Field Conditions.

    PubMed

    Duan, Lingfeng; Han, Jiwan; Guo, Zilong; Tu, Haifu; Yang, Peng; Zhang, Dong; Fan, Yuan; Chen, Guoxing; Xiong, Lizhong; Dai, Mingqiu; Williams, Kevin; Corke, Fiona; Doonan, John H; Yang, Wanneng

    2018-01-01

    Dynamic quantification of drought response is a key issue both for variety selection and for functional genetic study of rice drought resistance. Traditional assessment of drought resistance traits, such as stay-green and leaf-rolling, has utilized manual measurements, that are often subjective, error-prone, poorly quantified and time consuming. To relieve this phenotyping bottleneck, we demonstrate a feasible, robust and non-destructive method that dynamically quantifies response to drought, under both controlled and field conditions. Firstly, RGB images of individual rice plants at different growth points were analyzed to derive 4 features that were influenced by imposition of drought. These include a feature related to the ability to stay green, which we termed greenness plant area ratio (GPAR) and 3 shape descriptors [total plant area/bounding rectangle area ratio (TBR), perimeter area ratio (PAR) and total plant area/convex hull area ratio (TCR)]. Experiments showed that these 4 features were capable of discriminating reliably between drought resistant and drought sensitive accessions, and dynamically quantifying the drought response under controlled conditions across time (at either daily or half hourly time intervals). We compared the 3 shape descriptors and concluded that PAR was more robust and sensitive to leaf-rolling than the other shape descriptors. In addition, PAR and GPAR proved to be effective in quantification of drought response in the field. Moreover, the values obtained in field experiments using the collection of rice varieties were correlated with those derived from pot-based experiments. The general applicability of the algorithms is demonstrated by their ability to probe archival Miscanthus data previously collected on an independent platform. In conclusion, this image-based technology is robust providing a platform-independent tool for quantifying drought response that should be of general utility for breeding and functional genomics in future.

  10. Heat shock increases oxidative stress to modulate growth and physico-chemical attributes in diverse maize cultivars

    NASA Astrophysics Data System (ADS)

    Hussain, Iqbal; Ashraf, Muhammad Arslan; Rasheed, Rizwan; Iqbal, Muhammad; Ibrahim, Muhammad; Ashraf, Shamila

    2016-10-01

    The present investigation was conducted to appraise the physiochemical adjustments in contrasting maize cultivars, namely, PakAfgoi (tolerant) and EV-5098 (sensitive) subjected to heat shock. Seven-day-old seedlings were exposed to heat shock for different time intervals (1, 3, 6, 24, 48 and 72 h) and data for various physiochemical attributes determined to appraise time course changes in maize. After 72 h of heat shock, the plants were grown under normal conditions for 5 d and data for different growth attributes and photosynthetic pigments recorded. Exposure to heat shock reduced growth and photosynthetic pigments in maize cultivars. The plants exposed to heat shock for up to 3 h recovered growth and photosynthetic pigments when stress was relieved. A time course rise in the relative membrane permeability, hydrogen peroxide (H2O2) and malondialdehyde contents was recorded particularly in the EV-5098 indicating that heat shock-induced oxidative stress. Activities of different enzymatic antioxidants greatly altered due to heat shock. For instance, an increase in superoxide dismutase activity was recorded in both maize cultivars. The activity of ascorbate peroxidase was greater in Pak-Afgoi. However, the peroxidase and catalase activities were higher in plants of EV-5098. Heat shock caused a significant rise in the proline and decline in the total free amino acids. Overall, the performance of Pak-Afgoi was better in terms of having lesser oxidative damage and greater cellular levels of proline. The results suggested that oxidative stress indicators (relative membrane permeability, H2O2 and malondialdehyde) and proline can be used as markers for heat shock tolerant plants.

  11. Prescribed fire and cutting as tools for reducing woody plant succession in a created salt marsh

    USGS Publications Warehouse

    Owens, A.B.; Proffitt, C.E.; Grace, J.B.

    2007-01-01

    This paper reports on efforts to reduce woody successional growth by the native shrub Iva frutescens L. in a created salt marsh by using prescribed fire and cutting. Experimental treatments included a winter burn, cutting plants at ground level, and a combination burn-and-cut treatment, with replicate plots of each. Iva frutescens proved to be extremely hardy, with zero mortality following the cutting, burning, or combination treatment; similar levels of regrowth were observed for all treatments. Individual shrub response, however, was found to be related to initial plant size, ground water level and salinity, and two fire characteristics (total heating >60??C and total heat index >60??C). Fire severity, sediment nutrient concentrations, and other abiotic factors had no observable effects. ?? 2007 Springer Science+Business Media B.V.

  12. Army Sustainment. Volume 42, Issue 5, September-October 2010

    DTIC Science & Technology

    2010-10-01

    pollution ...creating power plants. Busi- ness prac tices that lead to increased vehicle traffic use more gasoline and create more exhaust pollution . Trash must be...replacing bottled water, which has been a prime target for environmentalists. At least one company offers a compostable plastic water bottle that

  13. Creating Teams Increases Extension Educator Productivity

    ERIC Educational Resources Information Center

    Chalker-Scott, Linda; Daniels, Catherine H.; Martini, Nicole

    2016-01-01

    The Garden Team at Washington State University is a transdisciplinary group of faculty, staff, and students with expertise in applied plant and soil sciences and an interest in Extension education. The team's primary mission is to create current, relevant, and peer-reviewed materials as Extension publications for home gardeners. The average yearly…

  14. Understanding cattail (typha spp.) invasion and persistence in forested wetlands created by the Virginia Department of Transportation.

    DOT National Transportation Integrated Search

    2009-01-01

    Common cattail (Typha latifolia) is a native plant species listed as an invasive weed by some regulatory agencies. While it is not listed as a noxious weed by the Commonwealth of Virginia, control of cattail populations in created forested wetlands i...

  15. 75 FR 62191 - Endangered and Threatened Wildlife and Plants; Revised Critical Habitat for Navarretia fossalis

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-07

    ... soil amendments or dryland farming activities (Roberts 2009, p. 2). Subsurface Water Flow That Creates... protection to reduce the following threats: habitat destruction and fragmentation from urban and agricultural...; fire suppression practices (including discing and plowing to remove weeds and create fire breaks...

  16. The Influence of Plant Root Systems on Subsurface Flow: Implications for Slope Stability

    EPA Science Inventory

    Although research has explained how plant roots mechanically stabilize soils, in this article we explore how root systems create networks of preferential flow and thus influence water pressures in soils to trigger landslides. Root systems may alter subsurface flow: Hydrological m...

  17. Plant growth responses to polypropylene--biocontainers

    USDA-ARS?s Scientific Manuscript database

    The influence of bio-fillers incorporated into polypropylene (PP) on the growth of plants was evaluated. Biocontainers were created by injection molding of PP with 25-40% by weight of Osage orange tree, Paulownia tree, coffee tree wood or dried distillers grain and 5% by weight of maleated polypropy...

  18. Transportation and storage of MOX and LEU assemblies at the Balakovo Nuclear Power Plant

    DOT National Transportation Integrated Search

    2001-01-01

    The VVER-1000-type Balakovo Nuclear Power Plant has been chosen to dispose of the : plutonium created as part of Russian weapons program. The plutonium will be converted to mixed-oxide : (MOX), fabricated into assemblies and loaded into the reactor. ...

  19. Cooling the Itch via TRPM8.

    PubMed

    Liu, Boyi; Jordt, Sven-Eric

    2018-06-01

    Cooling is an effective temporary remedy for itch, bringing welcome relief to itchy insect bites, nettle stings, poison ivy, atopic dermatitis, and psoriasis. Menthol, causing a cooling sensation, has similar itch-relieving effects. Palkar et al. demonstrate that TRPM8, a menthol- and cold-activated ion channel, is essential for cooling to relieve itch, suggesting that pharmacologic TRPM8 activation should be explored further as an antipruritic strategy. Copyright © 2018 The Authors. Published by Elsevier Inc. All rights reserved.

  20. Accomplishments under the Airport Improvement Program: Fiscal Year 1990 (Ninth Annual Report)

    DTIC Science & Technology

    1990-01-01

    ST PAUL 06 $259,200 INSTALL TAXIWAY SIGNS; EXTEND SERVICE ST PAUL DOWNTOWN HOLMAN FIELD ROAD (RELIEVER) THIEF RIVER FALLS 01 $69,075 INSTALL RUNWAY AND...TAXIWAY SIGNS THIEF RIVER FALLS REGIONAL (COMMERCIAL SERVICE) MISSISSIPPI S2 $101,000 CONDUCT STATE SYSTEM PLAN STUDY STATE OF MISSISSIPPI (SYSTEM...SOL5tRG-HUNTERDON (GENERAL AVIATION) TETERBORO 09 $174,103 ACQUIRE SNOW REMOVAL EQUIPMENT TETERBORO (RELIEVER) TOMS RIVER Oa $189,764 IMPROVE DRAINAGE

  1. Experience of low-dose aminophylline use to relieve minor adverse effects of dipyridamole in patients undergoing stress myocardial perfusion imaging.

    PubMed

    Lin, Li-Fan; Cheng, Cheng-Yi; Hou, Cheng-Han; Ku, Chih-Hung; Tseng, Neng-Chuan; Shen, Daniel H Y

    2014-06-01

    Intravenous administration of aminophylline is widely adopted to reverse dipyridamole-related adverse effects (AEs) during stress myocardial perfusion imaging (MPI). The study aimed to investigate the efficacy of lower-dose aminophylline to relieve minor AEs. 2,250 consecutive patients undergoing dipyridamole-stressed MPI were enrolled. Information concerning AE occurrence and dosages of aminophylline was collected to evaluate the efficacy of lower-dose aminophylline. A logistic regression was used to determine independent predictors of dipyridamole-related AE occurrence. No severe AE was noted. Overall mild AE incidence was 37.0% (833/2,250 patients). Initial low-dose (25 mg) aminophylline relieved symptoms in 98.8% of patients with mild AEs (823/833 patients). An extra 25 mg aminophylline sufficed to reverse all such AEs. Mean body mass index (BMI) differed significantly between patients with and without any AE [25.6 vs 25.1 (P = .009)]. There was no significant difference between two subgroups in mean age, male gender prevalence, body height and weight, dipyridamole dose/BMI, or prevalence of significant perfusion defect(s) on MPI. Multivariable logistic regression demonstrated BMI remained the independent predictor of dipyridamole-related AE occurrence (odds ratio 1.028, 95% confidence interval 1.007-1.049, P = .01). Low-dose (≦50 mg, and usually 25 mg) aminophylline seems sufficient to relieve mild dipyridamole-related AEs during stress MPI.

  2. Evaluation of the efficacy of two mouthrinses formulated for the relief of xerostomia of diverse origin in adult subjects.

    PubMed

    Morales-Bozo, Irene; Rojas, Gonzalo; Ortega-Pinto, Ana; Espinoza, Iris; Soto, Lilian; Plaza, Anita; Lozano, Carla; Urzúa, Blanca

    2012-06-01

    To evaluate the efficacy of two new mouthrinses in the reduction of xerostomía-associated symptomatology. Xerostomia is a common chronic health condition that affects a great number of adults and significantly deteriorates quality of life, such that treatment is necessary. Sixty-seven adult subjects of both sexes presenting xerostomia of diverse origin were selected. Mouthrinses were tested using a double-blind, randomized, cross-over clinical trial with an intervining wash out period. The 100% of subjects presented sensation of dry mouth, and 86% stated sensation of thick saliva. Burning tongue sensation, need to drink liquids to swallow and the sensation of swallowing difficulty were recorded in more than 50% of the patients. The most frequent pathologies in the sample were depression, arthritis, and arterial hypertension. Results of the clinical tests showed that mouthrinse 1 relieves sensation of dry mouth, need to drink liquids, and swallowing difficulty. In contrast, mouthrinse 2 relieves only latter two symptoms. Both rinses were more effective in relieving xerostomía-associated symptomatology in patients taking 3 or more medicines simultaneously. Both mouthrinses were effective in relieving various xerostomia symptoms, could be distributed at a low cost, thereby improving the quality of life of population affected. © 2012 The Gerodontology Society and John Wiley & Sons A/S.

  3. PKA activity is essential for relieving the suppression of hyphal growth and appressorium formation by MoSfl1 in Magnaporthe oryzae

    PubMed Central

    Li, Yang; Zhang, Xue

    2017-01-01

    In the rice blast fungus Magnaporthe oryzae, the cAMP-PKA pathway regulates surface recognition, appressorium turgor generation, and invasive growth. However, deletion of CPKA failed to block appressorium formation and responses to exogenous cAMP. In this study, we generated and characterized the cpk2 and cpkA cpk2 mutants and spontaneous suppressors of cpkA cpk2 in M. oryzae. Our results demonstrate that CPKA and CPK2 have specific and overlapping functions, and PKA activity is essential for appressorium formation and plant infection. Unlike the single mutants, the cpkA cpk2 mutant was significantly reduced in growth and rarely produced conidia. It failed to form appressoria although the intracellular cAMP level and phosphorylation of Pmk1 MAP kinase were increased. The double mutant also was defective in plant penetration and Mps1 activation. Interestingly, it often produced fast-growing spontaneous suppressors that formed appressoria but were still non-pathogenic. Two suppressor strains of cpkA cpk2 had deletion and insertion mutations in the MoSFL1 transcription factor gene. Deletion of MoSFL1 or its C-terminal 93-aa (MoSFL1ΔCT) was confirmed to suppress the defects of cpkA cpk2 in hyphal growth but not appressorium formation or pathogenesis. We also isolated 30 spontaneous suppressors of the cpkA cpk2 mutant in Fusarium graminearum and identified mutations in 29 of them in FgSFL1. Affinity purification and co-IP assays showed that this C-terminal region of MoSfl1 was essential for its interaction with the conserved Cyc8-Tup1 transcriptional co-repressor, which was reduced by cAMP treatment. Furthermore, the S211D mutation at the conserved PKA-phosphorylation site in MoSFL1 partially suppressed the defects of cpkA cpk2. Overall, our results indicate that PKA activity is essential for appressorium formation and proper activation of Pmk1 or Mps1 in M. oryzae, and phosphorylation of MoSfl1 by PKA relieves its interaction with the Cyc8-Tup1 co-repressor and suppression of genes important for hyphal growth. PMID:28806765

  4. Chemical signaling between plants and plant-pathogenic bacteria.

    PubMed

    Venturi, Vittorio; Fuqua, Clay

    2013-01-01

    Studies of chemical signaling between plants and bacteria in the past have been largely confined to two models: the rhizobial-legume symbiotic association and pathogenesis between agrobacteria and their host plants. Recent studies are beginning to provide evidence that many plant-associated bacteria undergo chemical signaling with the plant host via low-molecular-weight compounds. Plant-produced compounds interact with bacterial regulatory proteins that then affect gene expression. Similarly, bacterial quorum-sensing signals result in a range of functional responses in plants. This review attempts to highlight current knowledge in chemical signaling that takes place between pathogenic bacteria and plants. This chemical communication between plant and bacteria, also referred to as interkingdom signaling, will likely become a major research field in the future, as it allows the design of specific strategies to create plants that are resistant to plant pathogens.

  5. Plant Chemistry and Local Adaptation of a Specialized Folivore

    PubMed Central

    Laukkanen, Liisa; Leimu, Roosa; Muola, Anne; Lilley, Marianna; Salminen, Juha-Pekka; Mutikainen, Pia

    2012-01-01

    Local adaptation is central for creating and maintaining spatial variation in plant-herbivore interactions. Short-lived insect herbivores feeding on long-lived plants are likely to adapt to their local host plants, because of their short generation time, poor dispersal, and geographically varying selection due to variation in plant defences. In a reciprocal feeding trial, we investigated the impact of geographic variation in plant secondary chemistry of a long-lived plant, Vincetoxicum hirundinaria, on among-population variation in local adaptation of a specialist leaf-feeding herbivore, Abrostola asclepiadis. The occurrence and degree of local adaptation varied among populations. This variation correlated with qualitative and quantitative differences in plant chemistry among the plant populations. These findings provide insights into the mechanisms driving variation in local adaptation in this specialized plant-herbivore interaction. PMID:22666493

  6. Challenges and opportunities for improving food quality and nutrition through plant biotechnology.

    PubMed

    Francis, David; Finer, John J; Grotewold, Erich

    2017-04-01

    Plant biotechnology has been around since the advent of humankind, resulting in tremendous improvements in plant cultivation through crop domestication, breeding and selection. The emergence of transgenic approaches involving the introduction of defined DNA sequences into plants by humans has rapidly changed the surface of our planet by further expanding the gene pool used by plant breeders for plant improvement. Transgenic approaches in food plants have raised concerns on the merits, social implications, ecological risks and true benefits of plant biotechnology. The recently acquired ability to precisely edit plant genomes by modifying native genes without introducing new genetic material offers new opportunities to rapidly exploit natural variation, create new variation and incorporate changes with the goal to generate more productive and nutritious plants. Copyright © 2016 Elsevier Ltd. All rights reserved.

  7. USSR Report, Life Sciences Biomedical and Behavioral Sciences.

    DTIC Science & Technology

    1983-09-13

    created by the lengthy pro- cesses of evolution and selection, as well as methods for selecting and evaluating plants at the first stages of the...27 May 83) 17 Soviets-American Symposium in Alma-Ata on Plant Proteins and Nutrition (N. Idrisov? KAZAKHSTANSKAYA PRAVDA, 26 Feb 83).., 19...MIKROBIOLOGIYA, Nov-Dec 82),.,,. 38 MOLECULAR BIOLOGY New Research Institute of Plant Molecular Biology and Biochemistry in Alma-Ata (Murat

  8. Spatial and temporal optimization in habitat placement for a threatened plant: the case of the western prairie fringed orchid

    Treesearch

    John Hof; Carolyn Hull Sieg; Michael Bevers

    1999-01-01

    This paper investigates an optimization approach to determining the placement and timing of habitat protection for the western prairie fringed orchid. This plant’s population dynamics are complex, creating a challenging optimization problem. The sensitivity of the orchid to random climate conditions is handled probabilistically. The plant’s seed, protocorm and above-...

  9. The use of agrobiodiversity for plant improvement and the intellectual property paradigm: institutional fit and legal tools for mass selection, conventional and molecular plant breeding.

    PubMed

    Batur, Fulya; Dedeurwaerdere, Tom

    2014-12-01

    Focused on the impact of stringent intellectual property mechanisms over the uses of plant agricultural biodiversity in crop improvement, the article delves into a systematic analysis of the relationship between institutional paradigms and their technological contexts of application, identified as mass selection, controlled hybridisation, molecular breeding tools and transgenics. While the strong property paradigm has proven effective in the context of major leaps forward in genetic engineering, it faces a systematic breakdown when extended to mass selection, where innovation often displays a collective nature. However, it also creates partial blockages in those innovation schemes rested between on-farm observation and genetic modification, i.e. conventional plant breeding and upstream molecular biology research tools. Neither overly strong intellectual property rights, nor the absence of well delineated protection have proven an optimal fit for these two intermediary socio-technological systems of cumulative incremental innovation. To address these challenges, the authors look at appropriate institutional alternatives which can create effective incentives for in situ agrobiodiversity conservation and the equitable distribution of technologies in plant improvement, using the flexibilities of the TRIPS Agreement, the liability rules set forth in patents or plant variety rights themselves (in the form of farmers', breeders' and research exceptions), and other ad hoc reward regimes.

  10. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Thompson, R.L.; Wade, G.L.; Straw, R.A.

    A descriptive study of the naturally invading and planted flora was conducted during 1984-1985 on a 14- and 21-year-old contour surface mine the 14.2 ha Log Mountain Demonstration Area (LMDA), in Bell County, Kentucky. Six habitats are designated from areas created from coal mining; the 1963 bench, 1970 bench, bench highwalls, mine outslopes, mine seeps, and coal haul-telephone microwave tower road. Twenty-four of 25 woody and herbaceous species (11 indigenous, 13 non-indigenous) have persisted from plantings by personnel of the Northeastern Forest Experiment Station, USDA Forest Service. We recommend 11 native and exotic woody and herbaceous species for planting onmore » coal surface-mined areas. An annotated list of vascular plants comprises 360 taxa (286 indigenous, 74 non-indigenous) in 224 genera from 82 families. Taxa consist of 1 Lycopodiophyta, 1 Equisetophyta, 8 Polypodiophyta, 7 Pinophyta, and 343 Magnoliophyta. The most species-rich families are the Asteraceae (64), Poaceae (39), Fabaceae (20), Cyperaceae (16), Rosaceae (13), and Lamiaceae (11). A total of 155 Bell County distribution records were documented. Three threatened Kentucky species (Gentiana decora, Liparis loeselii, Silene ovata) were present in refugial habitats created by surface mining. The high species richness has resulted from native and naturalized invading species from the environs, native and exotic planted species, and species from the remnant seed bank. Forest vegetation is a complex mosaic of natural and semi-natural plant communities on the unplanted and planted areas of LMDA.« less

  11. Initial empirical analysis of nuclear power plant organization and its effect on safety performance

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Olson, J.; McLaughlin, S.D.; Osborn, R.N.

    This report contains an analysis of the relationship between selected aspects of organizational structure and the safety-related performance of nuclear power plants. The report starts by identifying and operationalizing certain key dimensions of organizational structure that may be expected to be related to plant safety performance. Next, indicators of plant safety performance are created by combining existing performance measures into more reliable indicators. Finally, the indicators of plant safety performance using correlational and discriminant analysis. The overall results show that plants with better developed coordination mechanisms, shorter vertical hierarchies, and a greater number of departments tend to perform more safely.

  12. Water-Related Power Plant Curtailments: An Overview of Incidents and Contributing Factors

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    McCall, James; Macknick, Jordan; Macknick, Jordan

    Water temperatures and water availability can affect the reliable operations of power plants in the United States. Data on water-related impacts on the energy sector are not consolidated and are reported by multiple agencies. This study provides an overview of historical incidents where water resources have affected power plant operations, discusses the various data sources providing information, and creates a publicly available and open access database that contains consolidated information about water-related power plant curtailment and shut-down incidents. Power plants can be affected by water resources if incoming water temperatures are too high, water discharge temperatures are too high, ormore » if there is not enough water available to operate. Changes in climate have the potential to exacerbate uncertainty over water resource availability and temperature. Power plant impacts from water resources include curtailment of generation, plant shut-downs, and requests for regulatory variances. In addition, many power plants have developed adaptation approaches to reducing the potential risks of water-related issues by investing in new technologies or developing and implementing plans to undertake during droughts or heatwaves. This study identifies 42 incidents of water-related power plant issues from 2000-2015, drawing from a variety of different datasets. These incidents occur throughout the U.S., and affect coal and nuclear plants that use once-through, recirculating, and pond cooling systems. In addition, water temperature violations reported to the Environmental Protection Agency are also considered, with 35 temperature violations noted from 2012-2015. In addition to providing some background information on incidents, this effort has also created an open access database on the Open Energy Information platform that contains information about water-related power plant issues that can be updated by users.« less

  13. Discovery Central

    ERIC Educational Resources Information Center

    Wood, Jaimee

    2005-01-01

    Spring is an exciting time in any kindergarten classroom. The children are communicating better, and they have begun working more independently. Their critical-thinking skills are growing each day. Last year, as the warm days of spring teased our senses, a plant unit seemed especially enticing, so the author created four interactive, plant-themed…

  14. Horizontal gene acquisitions, mobile element proliferation, and genome decay in the host-restricted plant pathogen erwinia tracheiphila

    USDA-ARS?s Scientific Manuscript database

    Modern industrial agriculture depends on high-density cultivation of genetically similar crop plants, creating favorable conditions for the emergence of novel pathogens with increased fitness in managed compared with ecologically intact settings. Here, we present the genome sequence of six strains o...

  15. Az-Tech Medicine.

    ERIC Educational Resources Information Center

    Nicholson, Rob

    2000-01-01

    Created in 1552 as a gift for Spain's king, the Badianus Manuscript is a repository of Aztec traditional medicinal knowledge and contains the earliest surviving illustrations of New World plants. At the College of Santa Cruz (Mexico City) for Aztec nobility, an Aztec healer who became the college physician compiled plant descriptions and medicinal…

  16. Perspectives for genomic selection applications and research in plants

    USDA-ARS?s Scientific Manuscript database

    Genomic selection (GS) has created a lot of excitement and expectations in the animal and plant breeding research communities. In this review, we briefly describe how genomic prediction can be integrated into breeding efforts and point out achievements and areas where more research is needed. GS pro...

  17. Microgravity

    NASA Image and Video Library

    1998-10-01

    International Flavors and Fragrances Inc., is a company that creates and manufactures flavors, fragrances and aroma chemicals. The Overnight Scentsation rose plant will be housed aboard NASA's shuttle flight STS-95 in a specially-designed structure under ultraviolet lights. The flowering plant was brought to Cape Canaveral from its home at IFF's greenhouse in Union Beach, New Jersey.

  18. Engineering Encounters: The Internet of Things for Kids

    ERIC Educational Resources Information Center

    Davis, Tiffany

    2017-01-01

    This column presents ideas and techniques to enhance science teaching. In the "Talking Window Garden" project, students create "smart" plant pots that use sensors to collect and analyze data on the health of their plants. The Talking Window Garden project was a collaborative effort between an elementary teacher who wanted to…

  19. Spatial heterogeneity in soil microbes alters outcomes of plant competition.

    PubMed

    Abbott, Karen C; Karst, Justine; Biederman, Lori A; Borrett, Stuart R; Hastings, Alan; Walsh, Vonda; Bever, James D

    2015-01-01

    Plant species vary greatly in their responsiveness to nutritional soil mutualists, such as mycorrhizal fungi and rhizobia, and this responsiveness is associated with a trade-off in allocation to root structures for resource uptake. As a result, the outcome of plant competition can change with the density of mutualists, with microbe-responsive plant species having high competitive ability when mutualists are abundant and non-responsive plants having high competitive ability with low densities of mutualists. When responsive plant species also allow mutualists to grow to greater densities, changes in mutualist density can generate a positive feedback, reinforcing an initial advantage to either plant type. We study a model of mutualist-mediated competition to understand outcomes of plant-plant interactions within a patchy environment. We find that a microbe-responsive plant can exclude a non-responsive plant from some initial conditions, but it must do so across the landscape including in the microbe-free areas where it is a poorer competitor. Otherwise, the non-responsive plant will persist in both mutualist-free and mutualist-rich regions. We apply our general findings to two different biological scenarios: invasion of a non-responsive plant into an established microbe-responsive native population, and successional replacement of non-responders by microbe-responsive species. We find that resistance to invasion is greatest when seed dispersal by the native plant is modest and dispersal by the invader is greater. Nonetheless, a native plant that relies on microbial mutualists for competitive dominance may be particularly vulnerable to invasion because any disturbance that temporarily reduces its density or that of the mutualist creates a window for a non-responsive invader to establish dominance. We further find that the positive feedbacks from associations with beneficial soil microbes create resistance to successional turnover. Our theoretical results constitute an important first step toward developing a general understanding of the interplay between mutualism and competition in patchy landscapes, and generate qualitative predictions that may be tested in future empirical studies.

  20. Spatial Heterogeneity in Soil Microbes Alters Outcomes of Plant Competition

    PubMed Central

    Abbott, Karen C.; Karst, Justine; Biederman, Lori A.; Borrett, Stuart R.; Hastings, Alan; Walsh, Vonda; Bever, James D.

    2015-01-01

    Plant species vary greatly in their responsiveness to nutritional soil mutualists, such as mycorrhizal fungi and rhizobia, and this responsiveness is associated with a trade-off in allocation to root structures for resource uptake. As a result, the outcome of plant competition can change with the density of mutualists, with microbe-responsive plant species having high competitive ability when mutualists are abundant and non-responsive plants having high competitive ability with low densities of mutualists. When responsive plant species also allow mutualists to grow to greater densities, changes in mutualist density can generate a positive feedback, reinforcing an initial advantage to either plant type. We study a model of mutualist-mediated competition to understand outcomes of plant-plant interactions within a patchy environment. We find that a microbe-responsive plant can exclude a non-responsive plant from some initial conditions, but it must do so across the landscape including in the microbe-free areas where it is a poorer competitor. Otherwise, the non-responsive plant will persist in both mutualist-free and mutualist-rich regions. We apply our general findings to two different biological scenarios: invasion of a non-responsive plant into an established microbe-responsive native population, and successional replacement of non-responders by microbe-responsive species. We find that resistance to invasion is greatest when seed dispersal by the native plant is modest and dispersal by the invader is greater. Nonetheless, a native plant that relies on microbial mutualists for competitive dominance may be particularly vulnerable to invasion because any disturbance that temporarily reduces its density or that of the mutualist creates a window for a non-responsive invader to establish dominance. We further find that the positive feedbacks from associations with beneficial soil microbes create resistance to successional turnover. Our theoretical results constitute an important first step toward developing a general understanding of the interplay between mutualism and competition in patchy landscapes, and generate qualitative predictions that may be tested in future empirical studies. PMID:25946068

  1. Relieving the cardiometabolic disease burden: a perspective on phytometabolite functional and chemical annotation for diabetes management.

    PubMed

    Janero, David R

    2014-01-01

    Type 2 diabetes (T2D) is both a complex, multifactorial disease state and an unsolved, intensifying public-health problem. To help reduce disease burden, some T2D patients have embraced plant-derived substances for use with - if not in place of - prescription medicines, a trend based mainly upon historical precedent and anecdotal observations of human health benefit. Preclinical research has emphasized phytometabolite interactions with purported T2D pathogenic targets and the effects of botanical preparations on experimental T2D symptomology as induced in laboratory animals. More holistic, systems-oriented profiling of phytochemicals with functional-biology, omics, and chemical-fingerprinting tools now appears necessary to increase our appreciation of phytometabolite actions potentially beneficial to the T2D patient. The resultant, multidimensional view of phytometabolite pharmacology should help provide a more rational basis for evaluating the potential of natural plant products as T2D pharmacotherapy. Such information may also help substantiate and legitimize (pre)clinical demonstrations of phytochemical health benefits, advance our understanding of T2D pathogenesis, and offer scope for better T2D medicines. Public-private partnerships are invoked for conducting this research with the ultimate aim of improving the global cardiometabolic profile.

  2. Hyptis suaveolens (L.) Poit (Lamiaceae), a medicinal plant protects the stomach against several gastric ulcer models.

    PubMed

    Jesus, N Z T; Falcão, H S; Lima, G R M; Caldas Filho, M R D; Sales, I R P; Gomes, I F; Santos, S G; Tavares, J F; Barbosa-Filho, J M; Batista, L M

    2013-12-12

    Hyptis suaveolens is used by the traditional population in several parts of the world to treat inflammation, gastric ulcer and infection and is used as a crude drug to relieve symptoms related with gastric ulcer or gastritis in northeaster and central region of Brazil. the standardized ethanolic extract (Hs-EtOHE) and hexanic fraction (Hs-HexF) of Hyptis suaveolens (62,5, 125, 250 and 500 mg/kg) was evaluated in several models of acute gastric ulcers. The participation of NO was evaluated by pretreatment with L-NAME and non-protein sulfyhydryls by NEM in the gastroprotective effect. Hs-EtOHE and Hs-HexF markedly reduced the gastric lesions induced by all ulcerogenic agents (HCl/ethanol, ethanol, NSAIDs and hypothermic restraint-stress). Gastric ulcerations were exacerbated by administration of NEM suggesting that the gastroprotective mechanism of action of Hs-EtOHE and Hs-HexF involves sulfhydryl groups. Ours results show that an extract of Hyptis suaveolens, administered orally to rodents, present gastro protective activity in different models of acute of gastric ulcer and give some support to the reported claims on the use of this plant as a gastro protective agent. © 2013 Published by Elsevier Ireland Ltd.

  3. Influence of irradiation time and solution concentration on the photochemical degradation of EDDHA/Fe3+: effect of its photodecomposition products on soybean growth.

    PubMed

    Hernández-Apaolaza, Lourdes; Lucena, Juan J

    2011-08-30

    Ethylenediamine-N, N'-bis(2-hydroxyphenylacetic acid (EDDHA) is one of the most efficient iron-chelating agents employed to relieve iron chlorosis in plants. It has been well known for decades that this compound is photosensitive, but in spite of this fact its degradation pathways are virtually unknown. The aim of this work was to evaluate how the length of sunlight exposure and the concentration of irradiated EDDHA/Fe(3+) solutions influence the photostability of the chelate at constant pH. Moreover, the possible toxic effect of the chelate photodegradation products, elsewhere proposed, on soybean growth has been tested. The photodecomposition of the chelate increased as the time of sunlight exposure increased, and resulted in a partial decomposition of the organic ligand. Moreover, EDDHA/Fe(3+) photodecomposition was highly correlated with the concentration of solution exposed. Plants did not present differences in recovery from chlorosis among treatments with and without decomposition products. EDDHA/Fe(3+) undergoes photodegradation, like other aminopolycarboxylic acids, being more degraded as solution concentration decreases and exposure time increases. The photodecomposition products salicylic acid, salicylaldehide and Salicylaldehyde ethylenediamine diimine tested did not have negative effects on soybean growth, at least in the short-term hydroponic experimental design tested. Copyright © 2011 Society of Chemical Industry.

  4. Alteration of Neutrophil Reactive Oxygen Species Production by Extracts of Devil's Claw (Harpagophytum).

    PubMed

    Muzila, Mbaki; Rumpunen, Kimmo; Wright, Helen; Roberts, Helen; Grant, Melissa; Nybom, Hilde; Sehic, Jasna; Ekholm, Anders; Widén, Cecilia

    2016-01-01

    Harpagophytum, Devil's Claw, is a genus of tuberiferous xerophytic plants native to southern Africa. Some of the taxa are appreciated for their medicinal effects and have been traditionally used to relieve symptoms of inflammation. The objectives of this pilot study were to investigate the antioxidant capacity and the content of total phenols, verbascoside, isoverbascoside, and selected iridoids, as well as to investigate the capacity of various Harpagophytum taxa in suppressing respiratory burst in terms of reactive oxygen species produced by human neutrophils challenged with phorbol myristate acetate (PMA), opsonised Staphylococcus aureus, and Fusobacterium nucleatum. Harpagophytum plants were classified into different taxa according to morphology, and DNA analysis was used to confirm the classification. A putative new variety of H. procumbens showed the highest degree of antioxidative capacity. Using PMA, three Harpagophytum taxa showed anti-inflammatory effects with regard to the PBS control. A putative hybrid between H. procumbens and H. zeyheri in contrast showed proinflammatory effect on the response of neutrophils to F. nucleatum in comparison with treatment with vehicle control. Harpagophytum taxa were biochemically very variable and the response in suppressing respiratory burst differed. Further studies with larger number of subjects are needed to corroborate anti-inflammatory effects of different taxa of Harpagophytum.

  5. Alteration of Neutrophil Reactive Oxygen Species Production by Extracts of Devil's Claw (Harpagophytum)

    PubMed Central

    Muzila, Mbaki; Wright, Helen; Roberts, Helen; Grant, Melissa; Nybom, Hilde; Sehic, Jasna; Ekholm, Anders

    2016-01-01

    Harpagophytum, Devil's Claw, is a genus of tuberiferous xerophytic plants native to southern Africa. Some of the taxa are appreciated for their medicinal effects and have been traditionally used to relieve symptoms of inflammation. The objectives of this pilot study were to investigate the antioxidant capacity and the content of total phenols, verbascoside, isoverbascoside, and selected iridoids, as well as to investigate the capacity of various Harpagophytum taxa in suppressing respiratory burst in terms of reactive oxygen species produced by human neutrophils challenged with phorbol myristate acetate (PMA), opsonised Staphylococcus aureus, and Fusobacterium nucleatum. Harpagophytum plants were classified into different taxa according to morphology, and DNA analysis was used to confirm the classification. A putative new variety of H. procumbens showed the highest degree of antioxidative capacity. Using PMA, three Harpagophytum taxa showed anti-inflammatory effects with regard to the PBS control. A putative hybrid between H. procumbens and H. zeyheri in contrast showed proinflammatory effect on the response of neutrophils to F. nucleatum in comparison with treatment with vehicle control. Harpagophytum taxa were biochemically very variable and the response in suppressing respiratory burst differed. Further studies with larger number of subjects are needed to corroborate anti-inflammatory effects of different taxa of Harpagophytum. PMID:27429708

  6. A Comprehensive Review on the Phytochemical Constituents and Pharmacological Activities of Pogostemon cablin Benth.: An Aromatic Medicinal Plant of Industrial Importance.

    PubMed

    Swamy, Mallappa Kumara; Sinniah, Uma Rani

    2015-05-12

    Pogostemon cablin Benth. (patchouli) is an important herb which possesses many therapeutic properties and is widely used in the fragrance industries. In traditional medicinal practices, it is used to treat colds, headaches, fever, nausea, vomiting, diarrhea, abdominal pain, insect and snake bites. In aromatherapy, patchouli oil is used to relieve depression, stress, calm nerves, control appetite and to improve sexual interest. Till now more than 140 compounds, including terpenoids, phytosterols, flavonoids, organic acids, lignins, alkaloids, glycosides, alcohols, aldehydes have been isolated and identified from patchouli. The main phytochemical compounds are patchouli alcohol, α-patchoulene, β-patchoulene, α-bulnesene, seychellene, norpatchoulenol, pogostone, eugenol and pogostol. Modern studies have revealed several biological activities such as antioxidant, analgesic, anti-inflammatory, antiplatelet, antithrombotic, aphrodisiac, antidepressant, antimutagenic, antiemetic, fibrinolytic and cytotoxic activities. However, some of the traditional uses need to be verified and may require standardizing and authenticating the bioactivity of purified compounds through scientific methods. The aim of the present review is to provide comprehensive knowledge on the phytochemistry and pharmacological activities of essential oil and different plant extracts of patchouli based on the available scientific literature. This information will provide a potential guide in exploring the use of main active compounds of patchouli in various medical fields.

  7. The sustainability of a community pharmacy intervention to improve the quality use of asthma medication.

    PubMed

    Bereznicki, B; Peterson, G; Jackson, S; Walters, E H; Gee, P

    2011-04-01

    A previously published asthma intervention used a software application to data mine pharmacy dispensing records and generate a list of patients with potentially suboptimal management of their asthma; in particular, a high rate of provision of reliever medication. These patients were sent educational material from their community pharmacists and advised to seek a review of their asthma management from their general practitioner. The intervention resulted in a 3-fold improvement in the ratio of dispensed preventer medication (inhaled corticosteroids) to reliever medication (short-acting beta-2 agonists). This follow-up study aimed to determine the long-term effects of the intervention programme on the preventer-to-reliever (P:R) ratio. The same data mining software was modified so that it could re-identify patients who were originally targeted for the intervention. Community pharmacists who participated in the previous intervention installed the modified version of the software. The dispensing data were then de-identified, encrypted and transferred via the Internet to a secure server. The follow-up dispensing data for all patients were compared with their pre- and post-intervention data collected originally. Of the 1551 patients who were included in the original study, 718 (46·3%) were eligible to be included in the follow-up study. The improved P:R ratio was sustained for at least 12 months following the intervention (P < 0·01). The sustained increase in the P:R ratio was attributed to significant decreases in the average daily usage of reliever medication (P < 0·0001). The follow-up study demonstrated a sustained improvement in the ratio of dispensed preventer medication to reliever medication for asthma. The intervention has the potential to show long-lasting and widespread improvements in asthma management, improved health outcomes for patients, and ultimately, a reduced burden on the health system. © 2010 Blackwell Publishing Ltd.

  8. Comparison of plasma generated nitrogen fertilizer to conventional fertilizers ammonium nitrate and sodium nitrate for pre-emergent and seedling growth

    NASA Astrophysics Data System (ADS)

    Andhavarapu, A.; King, W.; Lindsay, A.; Byrns, B.; Knappe, D.; Fonteno, W.; Shannon, S.

    2014-10-01

    Plasma source generated nitrogen fertilizer is compared to conventional nitrogen fertilizers in water for plant growth. Root, shoot sizes, and weights are used to examine differences between plant treatment groups. With a simple coaxial structure creating a large-volume atmospheric glow discharge, a 162 MHz generator drives the air plasma. The VHF plasma source emits a steady state glow; the high drive frequency is believed to inhibit the glow-to-arc transition for non-thermal discharge generation. To create the plasma activated water (PAW) solutions used for plant treatment, the discharge is held over distilled water until a 100 ppm nitrate aqueous concentration is achieved. The discharge is used to incorporate nitrogen species into aqueous solution, which is used to fertilize radishes, marigolds, and tomatoes. In a four week experiment, these plants are watered with four different solutions: tap water, dissolved ammonium nitrate DI water, dissolved sodium nitrate DI water, and PAW. Ammonium nitrate solution has the same amount of total nitrogen as PAW; sodium nitrate solution has the same amount of nitrate as PAW. T-tests are used to determine statistical significance in plant group growth differences. PAW fertilization chemical mechanisms are presented.

  9. Prospects for arbuscular mycorrhizal fungi (AMF) to assist in phytoremediation of soil hydrocarbon contaminants.

    PubMed

    Rajtor, Monika; Piotrowska-Seget, Zofia

    2016-11-01

    Arbuscular mycorrhizal fungi (AMF) form mutualistic associations with the roots of 80-90% of vascular plant species and may constitute up to 50% of the total soil microbial biomass. AMF have been considered to be a tool to enhance phytoremediation, as their mycelium create a widespread underground network that acts as a bridge between plant roots, soil and rhizosphere microorganisms. Abundant extramatrical hyphae extend the rhizosphere thus creating the hyphosphere, which significantly increases the area of a plant's access to nutrients and contaminants. The paper presents and evaluates the role and significance of AMF in phytoremediation of hydrocarbon contaminated sites. We focused on (1) an impact of hydrocarbons on arbuscular mycorrhizal symbiosis, (2) a potential of AMF to enhance phytoremediation, (3) determinants that influence effectiveness of hydrocarbon removal from contaminated soils. This knowledge may be useful for selection of proper plant and fungal symbionts and crucial to optimize environmental conditions for effective AMF-mediated phytoremediation. It has been concluded that three-component phytoremediation systems based on synergistic interactions between plant roots, AMF and hydrocarbon-degrading microorganisms demonstrated high effectiveness in dissipation of organic pollutants in soil. Copyright © 2016 Elsevier Ltd. All rights reserved.

  10. Enhanced Nitrogen Availability in Karst Ecosystems by Oxalic Acid Release in the Rhizosphere

    PubMed Central

    Pan, Fujing; Liang, Yueming; Zhang, Wei; Zhao, Jie; Wang, Kelin

    2016-01-01

    In karst ecosystems, a high level of CaCO3 enhances the stabilization of soil organic matter (SOM) and causes nitrogen (N) and/or phosphorus (P) limitation in plants. Oxalic acid has been suggested to be involved in the nutrient-acquisition strategy of plants because its addition can temporarily relieve nutrient limitation. Therefore, understanding how oxalic acid drives N availability may help support successful vegetation restoration in the karst ecosystems of southwest China. We tested a model suggested by Clarholm et al. (2015) where oxalate reacts with Ca bridges in SOM, thus exposing previously protected areas to enzymatic attacks in a way that releases N for local uptake. We studied the effects of oxalic acid, microbial biomass carbon (MBC), and β-1,4-N-acetylglucosaminidase (NAG) on potential N mineralization rates in rhizosphere soils of four plant species (two shrubs and two trees) in karst areas. The results showed that rhizosphere soils of shrubs grown on formerly deforested land had significantly lower oxalic acid concentrations and NAG activity than that of trees in a 200-year-old forest. The levels of MBC in rhizosphere soils of shrubs were significantly lower than those of trees in the growing season, but the measure of shrubs and trees were similar in the non-growing season; the potential N mineralization rates showed a reverse pattern. Positive relationships were found among oxalic acid, MBC, NAG activity, and potential N mineralization rates for both shrubs and trees. This indicated that oxalic acid, microbes, and NAG may enhance N availability for acquisition by plants. Path analysis showed that oxalic acid enhanced potential N mineralization rates indirectly through inducing microbes and NAG activities. We found that the exudation of oxalic acid clearly provides an important mechanism that allows plants to enhance nutrient acquisition in karst ecosystems. PMID:27252713

  11. Enhancing Aluminum Reactivity by Exploiting Surface Chemistry and Mechanical Properties

    DTIC Science & Technology

    2015-06-01

    alter its mechanical properties . In bulk material processing , annealing and quenching metals such as Al can relieve residual stress and improve...increasing  Al  reactivity is to alter its mechanical  properties .  In bulk material  processing , annealing and quenching metals such as  Al  can relieve...mechanical properties . On a single particle level, affecting mechanical properties may also affect Al particle reactivity. Aluminum particles underwent

  12. Robot Drills Holes To Relieve Excess Tire Pressures

    NASA Technical Reports Server (NTRS)

    Carrott, David T.

    1996-01-01

    Small, relatively inexpensive, remotely controlled robot called "tire assault vehicle" (TAV) developed to relieve excess tire pressures to protect ground crew, aircraft equipment, and nearby vehicles engaged in landing tests of CV-990 Landing System Research Aircraft. Reduces costs and saves time in training, maintenance, and setup related to "yellow" and "red" tire conditions. Adapted to any heavy-aircraft environment in which ground-crew safety at risk because of potential for tire explosions. Also ideal as scout vehicle for performing inspections in hazardous locations.

  13. Underwater Facilities Inspections and Assessments at Philadelphia Naval Shipyard, Philadelphia, Pennsylvania. Volume 2.

    DTIC Science & Technology

    1983-10-01

    broken piles in a concentrated area . As a result, the relieving platform is unsupported and in this are loading should be restricted to 50 psf until...concentration of damaged piles occurs on Section A near Drydock No. 4 and until repairs are made, loading should be restricted to 100 psf in this area . The...a concentrated area . As a result, the relieving platform is unsup- * ported and in this area loading should be restricted to 50 psf until repairs

  14. [Application of blistering cupping].

    PubMed

    Gu, Xingui; Chen, Zelin; Chen, Bo; Fan, Yihua; Chen, Xianghong

    2016-11-12

    Blistering cupping is special as eliminating wind and dampness as well as removing phlegm and blood stasis, and it achieves effects through suction. In this paper we reviewed relevant literature combined with clinical experience so as to summarize its operation attention through exploring the origin, mechanism and application. We divide the progress into the blistering period, the phlegm-stasis-eliminating period, and the escharosis period according to the changes of bubble and the things pulled out. Blistering cupping creates ways to eliminate concrete unhealthy influences through smoothing meridians and collaterals, such as phlegm and retained fluid, dampness and blood stasis. Thus chronic diseases are relieved. Also,we propose the rules of "blistering acupoints being related to disease location as well as the nature of acupoints and diseases". The therapy has been used to treat diseases of respiratory system, osteoarticular, skin and subcutaneous tissue, mental and behavioral disorders, and tumor, among which the effects of intractable diseases of respiratory and osteoarticular systems are definite. It deserves to be further explored and promoted.

  15. Comparing in situ removal strategies for improving styrene bioproduction.

    PubMed

    McKenna, Rebekah; Moya, Luis; McDaniel, Matthew; Nielsen, David R

    2015-01-01

    As an important conventional monomer compound, the biological production of styrene carries significant promise with respect to creating novel sustainable materials. Since end-product toxicity presently limits styrene production by previously engineered Escherichia coli, in situ product removal by both solvent extraction and gas stripping were explored as process-based strategies for circumventing its inhibitory effects. In solvent extraction, the addition of bis(2-ethylhexyl)phthalate offered the greatest productivity enhancement, allowing net volumetric production of 836 ± 64 mg/L to be reached, representing a 320 % improvement over single-phase cultures. Gas stripping rates, meanwhile, were controlled by rates of bioreactor agitation and, to a greater extent, aeration. A periodic gas stripping protocol ultimately enabled up to 561 ± 15 mg/L styrene to be attained. Lastly, by relieving the effects of styrene toxicity, new insight was gained regarding subsequent factors limiting its biosynthesis in E. coli and strategies for future strain improvement are discussed.

  16. Head-Up; An interdisciplinary, participatory and co-design process informing the development of a novel head and neck support for people living with progressive neck muscle weakness.

    PubMed

    Reed, Heath; Langley, Joe; Stanton, Andy; Heron, Nicola; Clarke, Zoe; Judge, Simon; McCarthy, Avril; Squire, Gill; Quinn, Ann; Wells, Oliver; Tindale, Wendy; Baxter, Susan; Shaw, Pamela J; McDermott, Christopher J

    2014-01-01

    This paper presents the Head-Up project, that aims to provide innovative head support to help improve posture, relieve pain and aid communication for people living with progressive neck muscle weakness. The initial focus is motor neurone disease. The case study illustrates collaborative, interdisciplinary research and new product development underpinned by participatory design. The study was initiated by a 2-day stakeholder workshop followed by early proof-of-concept modelling and patient need evidence building. The work subsequently led to a successful NIHR i4i application funding a 24-month iterative design process, patenting, CE marking and clinical evaluation. The evaluation has informed amendments to the proposed design refered to here as the Sheffield Support Snood (SSS). The outcome positively demonstrates use and performance improvements over current neck orthoses and the process of multidisciplinary and user engagement has created a sense of ownership by MND participants, who have since acted as advocates for the product.

  17. An ethics of suffering: does it solve the problems we want to solve?: commentary.

    PubMed

    Edwards, Barbara Springer

    1991-01-01

    Erich H. Loewy proposes to elevate the moral obligation to prevent and relieve suffering to the level of a prima facie moral duty by delineating which beings are of primary moral worth and which are of secondary moral worth. Sentient beings have a capacity to suffer and are therefore of primary moral worth. Beings that are insentient cannot suffer; therefore such beings are only of secondary moral worth. Objects of secondary moral worth include patients in a persistent vegetative state (PVS) and brain-dead patients. This proposal, he says, would solve a number of problems in clinical bioethics. First, it would help to clarify our moral duties at the bedside. And secondly, by creating a hierarchy of moral values, it helps to differentiate which patients are owed our primary allegiance and resources. Despite his extensive and painstaking proof, I believe several questions remain about the use of the "capacity of sentient beings to suffer" as a basis for a universal grounding in ethics.

  18. Can physicians be replaced with gynecological teaching women to train medical students in their first pelvic examination? A pilot study from Northern Sweden.

    PubMed

    Grankvist, Olov; Olofsson, Anders D; Isaksson, Rose-Marie

    2014-07-01

    The main objective was to gain a deeper understanding of how medical students perceive and experience learning from gynecological teaching women (GTW) instead of physicians in their first pelvic examination. A second aim was to describe how the women experience their roles as GTW. Data were collected from individual interviews with 24 medical students from a medical school in Sweden and with 5 GTW. Discourse analysis was performed to acquire a deeper understanding of the informants' experiences and to understand social interactions. Five themes revealed in the medical students' experiences: "Hoping that anxiety will be replaced with security," "Meeting as equals creates a sense of calm," "Succeeding creates a sense of security for the future," "Wanting but not having the opportunity to learn more," and "Feeling relieved and grateful." One theme revealed in the GTW experiences: "Hoping to relate in a trustworthy way." To replace physicians with GTW may facilitate the learning process and may also help medical students improve their communicative skills. Using GTW will hopefully further improve students' basic medical examination techniques and physician-patient relationships. Since GTW seems to increase self-confidence and skills of medical students performing their first pelvic examination we recommend that the use of GTW is considered in the training of medical students. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  19. Plant-Based Dietary Patterns and Incidence of Type 2 Diabetes in US Men and Women: Results from Three Prospective Cohort Studies.

    PubMed

    Satija, Ambika; Bhupathiraju, Shilpa N; Rimm, Eric B; Spiegelman, Donna; Chiuve, Stephanie E; Borgi, Lea; Willett, Walter C; Manson, JoAnn E; Sun, Qi; Hu, Frank B

    2016-06-01

    Plant-based diets have been recommended to reduce the risk of type 2 diabetes (T2D). However, not all plant foods are necessarily beneficial. We examined the association of an overall plant-based diet and hypothesized healthful and unhealthful versions of a plant-based diet with T2D incidence in three prospective cohort studies in the US. We included 69,949 women from the Nurses' Health Study (1984-2012), 90,239 women from the Nurses' Health Study 2 (1991-2011), and 40,539 men from the Health Professionals Follow-Up Study (1986-2010), free of chronic diseases at baseline. Dietary data were collected every 2-4 y using a semi-quantitative food frequency questionnaire. Using these data, we created an overall plant-based diet index (PDI), where plant foods received positive scores, while animal foods (animal fats, dairy, eggs, fish/seafood, poultry/red meat, miscellaneous animal-based foods) received reverse scores. We also created a healthful plant-based diet index (hPDI), where healthy plant foods (whole grains, fruits, vegetables, nuts, legumes, vegetable oils, tea/coffee) received positive scores, while less healthy plant foods (fruit juices, sweetened beverages, refined grains, potatoes, sweets/desserts) and animal foods received reverse scores. Lastly, we created an unhealthful plant-based diet index (uPDI) by assigning positive scores to less healthy plant foods and reverse scores to healthy plant foods and animal foods. We documented 16,162 incident T2D cases during 4,102,369 person-years of follow-up. In pooled multivariable-adjusted analysis, both PDI and hPDI were inversely associated with T2D (PDI: hazard ratio [HR] for extreme deciles 0.51, 95% CI 0.47-0.55, p trend < 0.001; hPDI: HR for extreme deciles 0.55, 95% CI 0.51-0.59, p trend < 0.001). The association of T2D with PDI was considerably attenuated when we additionally adjusted for body mass index (BMI) categories (HR 0.80, 95% CI 0.74-0.87, p trend < 0.001), while that with hPDI remained largely unchanged (HR 0.66, 95% CI 0.61-0.72, p trend < 0.001). uPDI was positively associated with T2D even after BMI adjustment (HR for extreme deciles 1.16, 95% CI 1.08-1.25, p trend < 0.001). Limitations of the study include self-reported diet assessment, with the possibility of measurement error, and the potential for residual or unmeasured confounding given the observational nature of the study design. Our study suggests that plant-based diets, especially when rich in high-quality plant foods, are associated with substantially lower risk of developing T2D. This supports current recommendations to shift to diets rich in healthy plant foods, with lower intake of less healthy plant and animal foods.

  20. Digital Full-Scope Simulation of a Conventional Nuclear Power Plant Control Room, Phase 2: Installation of a Reconfigurable Simulator to Support Nuclear Plant Sustainability

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ronald L. Boring; Vivek Agarwal; Kirk Fitzgerald

    2013-03-01

    The U.S. Department of Energy’s Light Water Reactor Sustainability program has developed a control room simulator in support of control room modernization at nuclear power plants in the U.S. This report highlights the recent completion of this reconfigurable, full-scale, full-scope control room simulator buildout at the Idaho National Laboratory. The simulator is fully reconfigurable, meaning it supports multiple plant models developed by different simulator vendors. The simulator is full-scale, using glasstop virtual panels to display the analog control boards found at current plants. The present installation features 15 glasstop panels, uniquely achieving a complete control room representation. The simulator ismore » also full-scope, meaning it uses the same plant models used for training simulators at actual plants. Unlike in the plant training simulators, the deployment on glasstop panels allows a high degree of customization of the panels, allowing the simulator to be used for research on the design of new digital control systems for control room modernization. This report includes separate sections discussing the glasstop panels, their layout to mimic control rooms at actual plants, technical details on creating a multi-plant and multi-vendor reconfigurable simulator, and current efforts to support control room modernization at U.S. utilities. The glasstop simulator provides an ideal testbed for prototyping and validating new control room concepts. Equally importantly, it is helping create a standardized and vetted human factors engineering process that can be used across the nuclear industry to ensure control room upgrades maintain and even improve current reliability and safety.« less

  1. Minimally Invasive Microendoscopic Resection of the Transverse Process for Treatment of Low Back Pain with Bertolotti's Syndrome

    PubMed Central

    Sakai, Toshinori; Higashino, Kosaku; Goda, Yuichiro; Mineta, Kazuaki; Sairyo, Koichi

    2014-01-01

    Bertolotti's syndrome is characterized by anomalous enlargement of the transverse process of the most caudal lumbar segment, causing chronic and persistent low back pain or sciatica. We describe the case of a 45-year-old woman who presented with left sciatic pain and low back pain due to a recurrent lumbar disc herniation at L4-5 with Bertolotti's syndrome. Selective L5 nerve root block and local injection of lidocaine into the articulation between the transverse process and sacral ala temporarily relieved the left sciatic pain and low back pain, respectively. To confirm the effect of local injection on low back pain, we gave a second local injection, which once again relieved the low back pain. Microendoscopic resection of the pseudoarticulation region and discectomy successfully relieved all symptoms. This report illustrates the effectiveness of minimally invasive resection of the transverse process for the treatment of low back pain with Bertolotti's syndrome. PMID:25045566

  2. Pressure-relieving properties of a intra-operative warming device.

    PubMed

    Baker, E A; Leaper, D J

    2003-04-01

    The primary objective of this study was to determine differences in interface pressure between four mattress combinations: a standard operating table mattress, a pressure-relieving gel pad and an under-patient warming device set at 38 degrees C (Pegasus Inditherm System) and at ambient temperature. The secondary objective was to determine whether the warming device remains stable in extreme surgical positions. Interface pressures obtained with all four combinations were measured in 10 healthy volunteers using force sensing array technology. The warming device demonstrated better or equivalent pressure relief when compared with the standard gel pad. There was no significant difference in subject position 'shift' between the mattress, the gel pad and the warming device for either the Trendelenberg or reverse Trendelenberg positions. Both pressure-relieving mattresses and warming reduce intra-operative pressure damage. A mattress with both properties may further reduce pressure damage postoperatively. The warming device used in this study appears stable--subject 'slippage' was minimal in extreme positions. Research needs to be conducted among real anaesthetised patients to support these conclusions.

  3. Processing method for forming dislocation-free SOI and other materials for semiconductor use

    DOEpatents

    Holland, Orin Wayne; Thomas, Darrell Keith; Zhou, Dashun

    1997-01-01

    A method for preparing a silicon-on-insulator material having a relatively defect-free Si overlayer involves the implanting of oxygen ions within a silicon body and the interruption of the oxygen-implanting step to implant Si ions within the silicon body. The implanting of the oxygen ions develops an oxide layer beneath the surface of the silicon body, and the Si ions introduced by the Si ion-implanting step relieves strain which is developed in the Si overlayer during the implanting step without the need for any intervening annealing step. By relieving the strain in this manner, the likelihood of the formation of strain-induced defects in the Si overlayer is reduced. In addition, the method can be carried out at lower processing temperatures than have heretofore been used with SIMOX processes of the prior art. The principles of the invention can also be used to relieve negative strain which has been induced in a silicon body of relatively ordered lattice structure.

  4. Minimally Invasive Microendoscopic Resection of the Transverse Process for Treatment of Low Back Pain with Bertolotti's Syndrome.

    PubMed

    Takata, Yoichiro; Sakai, Toshinori; Higashino, Kosaku; Goda, Yuichiro; Mineta, Kazuaki; Sugiura, Kosuke; Sairyo, Koichi

    2014-01-01

    Bertolotti's syndrome is characterized by anomalous enlargement of the transverse process of the most caudal lumbar segment, causing chronic and persistent low back pain or sciatica. We describe the case of a 45-year-old woman who presented with left sciatic pain and low back pain due to a recurrent lumbar disc herniation at L4-5 with Bertolotti's syndrome. Selective L5 nerve root block and local injection of lidocaine into the articulation between the transverse process and sacral ala temporarily relieved the left sciatic pain and low back pain, respectively. To confirm the effect of local injection on low back pain, we gave a second local injection, which once again relieved the low back pain. Microendoscopic resection of the pseudoarticulation region and discectomy successfully relieved all symptoms. This report illustrates the effectiveness of minimally invasive resection of the transverse process for the treatment of low back pain with Bertolotti's syndrome.

  5. Surgical pain management at the Medical School of Salerno (11th-13th centuries).

    PubMed

    Giuffra, Valentina

    2013-06-01

    Before the advent of general anesthesia, only poorly effective remedies were known to relieve pain. Although classical medical authorities describe a number of elaborate surgical techniques, no references about some forms of anesthesia are reported. Only the authors of pharmaceutical or botanical texts mention the use of substances, especially mandrake, to induce sleep in the patient. The first and most detailed evidences of general anesthesia described in medical texts of the western world can be found at the Medical School of Salerno. However, the use of substances aimed to relieve pain or to induce sleep during surgery is mentioned only by the authors of pharmaceutical or botanical texts and not by surgeons. Furthermore, the efficacy of these preparations to produce a profound and lasting sleep is doubtful. The general impression is that surgeons knew how to relieve pain, but considered it a necessary appendix of surgery and therefore an incisive effort to eliminate it was not pursued.

  6. Creating a cryobank for germplasm of fruit and berry crops: methodological recommendations

    USDA-ARS?s Scientific Manuscript database

    Plant genetic resources are a national treasure in each country. They serve as a basis for developing new and improving existing varieties of plants. In Kazakhstan, a wide selection of cultivated and wild forms grow unique fruit and berry crops, including apple (Malus sieversii (Ledeb.) M. Roem., Ma...

  7. Arbuscular Mycorrhizal Fungi Can Benefit Heavy Metal Tolerance and Phytoremediation

    ERIC Educational Resources Information Center

    Forgy, David

    2012-01-01

    Sites contaminated by heavy metals, such as industrial waste sites, create unwelcoming environments for plant growth. Heavy metals can have a wide range of toxic effects such as replacing essential elements or disrupting enzyme function. While some heavy metals are essential to plant nutrition at low concentrations, high concentrations of any…

  8. Genetics of a sex-linked recessive red eye color mutant of the tarnished plant bug, Lygus lineolaris

    USDA-ARS?s Scientific Manuscript database

    An inbred colony of the tarnished plant bug, Lygus lineolaris (Palisot de Beauvois) (Miridae: Hemiptera), was observed to contain specimens with abnormal traits including red eyes, deformed antennae, and deformed legs. These specimens were isolated and back crossed to create stable phenotypic strain...

  9. 75 FR 48997 - NUREG-1946, “Inservice Testing of Pumps and Valves, and Inservice Examination and Testing of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-12

    ..., and Inservice Examination and Testing of Dynamic Restraints (Snubbers) at Nuclear Power Plants, Draft... Dynamic Restraints (Snubbers) at Nuclear Power Plants, Draft Report for Comment.'' DATES: Please submit... System (ADAMS): Publicly available documents created or received at the NRC are available electronically...

  10. Living Willow Huts

    ERIC Educational Resources Information Center

    Keeler, Rusty

    2007-01-01

    Living Willow Huts are inexpensive to make, fun to plant, easy to grow, and make beautiful spaces for children. They involve planting dormant willow shoots in the ground and weaving them into shapes that will sprout and grow over time. People have been creating similar living architecture throughout the world for centuries in the forms of living…

  11. The role of landscape anomalies in regional plant conservation

    Treesearch

    S. Kelso; C. Hall; G. Maentz

    2001-01-01

    Landscape anomalies are regionally restricted habitats created by unusual geologic, edaphic, or hydrologic factors. Barrens, cliff faces, canyons, hanging gardens, and playas are all examples of landscape anomalies in the arid Southwest. Such sites often harbor an unusual and rich flora, including endemic, disjunct, or relictual plant species. Using examples from our...

  12. Good genes – using germplasm and breeding to create new plants at the U.S. National Arboretum

    USDA-ARS?s Scientific Manuscript database

    The U.S. National Arboretum was established in 1927 and occupies 446 acres in Northeast Washington, D.C. Its mission is to enhance the economic, environmental, and aesthetic value of ornamental and landscape plants through long-term, multi-disciplinary research, conservation of genetic resources, an...

  13. Every Plant Has a Story

    ERIC Educational Resources Information Center

    Foster, Allan

    2007-01-01

    One of the author's pet projects is to demonstrate to teachers how easy it is to grow plants in the classroom. In order to create equitable schools in Ontario, teachers are mandated to honour diversity in their classrooms by celebrating a diversity of special significant days such as Ramadan, Kwansaa, Diwali and Chinese New Year. Not only does…

  14. 75 FR 29588 - Notice of Availability of the Models for Plant-Specific Adoption of Technical Specifications Task...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-26

    ... Documents Access and Management System (ADAMS) under Accession Number ML090510686. The proposed changes... Documents Access and Management System (ADAMS): Publicly available documents created or received at the NRC... expedited approval of plant-specific adoption of TSTF- 501, Revision 1. Documents: You can access publicly...

  15. 75 FR 26294 - Notice of Availability of the Models for Plant-Specific Adoption of Technical Specifications Task...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-11

    ... an errata sheet are available in the Agencywide Documents Access and Management System (ADAMS) under... Agencywide Documents Access and Management System (ADAMS): Publicly available documents created or received... facilitate expedited approval of plant-specific adoption of TSTF-493, Revision 4. Documents: You can access...

  16. GRIN-Global: An International Project to Develop a Global Plant Genebank and Information Management System

    USDA-ARS?s Scientific Manuscript database

    The mission of the GRIN-Global Project is to create a new, scalable version of the Germplasm Resource Information System (GRIN) to provide the world’s crop genebanks with a powerful, flexible, easy-to-use plant genetic resource (PGR) information management system. The system will help safeguard PGR ...

  17. GRIN-Global: An International Project to Develop a Global Plant Genebank and Information Management System

    USDA-ARS?s Scientific Manuscript database

    The mission of the GRIN-Global Project is to create a new, scalable version of the Germplasm Resource Information System (GRIN) to provide the world's crop genebanks with a powerful, flexible, easy-to-use plant genetic resource (PGR) information management system. The system will help safeguard PGR ...

  18. GRIN-Global: An International Project to Develop a Global Plant Genebank and Information Management System

    USDA-ARS?s Scientific Manuscript database

    The mission of the GRIN-Global Project is to create a new, scalable version of the Germplasm Resource Information System (GRIN) to provide the world’s crop genebanks with a powerful, flexible, easy-to-use plant genetic resource (PGR) information management system. The system will help safeguard PGR...

  19. GRIN-Global: An International Project to Develop a Global Plant Genebank Information Management System

    USDA-ARS?s Scientific Manuscript database

    The mission of the GRIN-Global Project is to create a new, scalable version of the Germplasm Resource Information System (GRIN) to provide the world’s crop genebanks with a powerful, flexible, easy-to-use plant genetic resource (PGR) information management system. The system will help safeguard PGR ...

  20. Evaluating Sustainability: Soap versus Biodiesel Production from Plant Oils

    ERIC Educational Resources Information Center

    Pohl, Nicola L. B.; Streff, Jennifer M.; Brokman, Steve

    2012-01-01

    Herein we describe a series of experiments for the undergraduate organic laboratory curriculum in which various plant oils (soybean, rapeseed, and olive) are subjected to saponification and transesterification reactions to create a set of compounds that can function as soaps or as fuels. The experiments introduce students to and asks them to…

  1. An Interactive Virtual Tour of a Milk Powder Plant

    ERIC Educational Resources Information Center

    Herritsch, Alfred; Rahim, Elin Abdul; Fee, Conan J.; Morison, Ken R.; Gostomski, Peter A.

    2013-01-01

    Immersive learning applications in chemical and process engineering are creating the opportunity to bring entire process plants to the student. While meant to complement field trips, in some cases, this is the only opportunity for students to engage with certain industrial sites due to site regulations (health and safety, hygiene, intellectual…

  2. Company Town Shutdown.

    ERIC Educational Resources Information Center

    Turnage, Martha A.

    Saltville, Virginia, is a former company town whose main employer, a soda ash plant, shut down on July 1, 1971. The closure of the chemical plant displaced 700 workers, and created a crisis that threatened not only the existence of the town, but of the entire region. In response, Virginia Highlands Community College (VHCC), in cooperation with the…

  3. Uranium Immobilization in an Iron-Rich Rhizosphere of a Native Wetland Plant from the Savannah River Site under Reducing Conditions

    EPA Science Inventory

    The hypothesis of this study was that iron plaque formed on the roots of wetland plants and their rhizospheres create environmental conditions favorable for iron reducing bacteria that promote the in situ immobilization of uranium. Greenhouse microcosm studies were conducted usin...

  4. Effects of Environmental Conditions on the Fitness Penalty in Herbicide Resistant Brachypodium hybridum

    PubMed Central

    Frenkel, Eyal; Matzrafi, Maor; Rubin, Baruch; Peleg, Zvi

    2017-01-01

    Herbicide-resistance mutations may impose a fitness penalty in herbicide-free environments. Moreover, the fitness penalty associated with herbicide resistance is not a stable parameter and can be influenced by ecological factors. Here, we used two Brachypodium hybridum accessions collected from the same planted forest, sensitive (S) and target-site resistance (TSR) to photosystem II (PSII) inhibitors, to study the effect of agro-ecological parameters on fitness penalty. Both accessions were collected in the same habitat, thus, we can assume that the genetic variance between them is relatively low. This allow us to focus on the effect of PSII TSR on plant fitness. S plants grains were significantly larger than those of the TSR plants and this was associated with a higher rate of germination. Under low radiation, the TSR plants showed a significant fitness penalty relative to S plants. S plants exhibiting dominance when both types of plants were grown together in a low-light environment. In contrast to previous documented studies, under high-light environment our TSR accession didn’t show any significant difference in fitness compared to the S accession. Nitrogen deficiency had significant effect on the R compared to the S accession and was demonstrated in significant yield reduction. TSR plants also expressed a high fitness penalty, relative to the S plants, when grown in competition with wheat plants. Two evolutionary scenarios can be suggested to explain the coexistence of both TSR and S plants in the same habitat. The application of PSII inhibitors may have created selective pressure toward TSR dominancy; termination of herbicide application gave an ecological advantage to S plants, creating changes in the composition of the seed bank. Alternatively, the high radiation intensities found in the Mediterranean-like climate may reduce the fitness penalty associated with TSR. Our results may suggest that by integrating non-herbicidal approaches into weed-management programs, we can reduce the agricultural costs associated with herbicide resistance. PMID:28217132

  5. Perceptions of impact: Invasive alien plants in the urban environment.

    PubMed

    Potgieter, Luke J; Gaertner, Mirijam; O'Farrell, Patrick J; Richardson, David M

    2018-06-08

    Many alien plant species are introduced to urban areas to create, augment or restore ecosystem services (ES). However, many of these species spread beyond original plantings, sometimes causing negative effects on existing ES or creating novel ecosystem disservices (EDS). An understanding of the perceptions of urban residents regarding invasive alien plants (IAPs) and the ES and EDS they provide is needed for the effective prioritisation of IAP management efforts in cities. Using the city of Cape Town, South Africa as a case study, we conducted questionnaire-based surveys (online and face-to-face) to determine the perceptions of urban residents regarding IAPs and their capacity to provide ES and EDS. Most urban residents perceive IAPs negatively (i.e. agreeing that they create EDS), but many recognise their importance in providing ES. Although most residents are not opposed to the management of IAPs, such actions are not perceived as a high priority relative to other environmental problems. Socio-demographic variables such as age, education, environmental awareness, and ethnicity shape urban residents' perceptions of IAPs. Older, more educated respondents were more likely to perceive IAPs negatively, while respondents with greater environmental awareness were aware of the benefits provided by IAPs. This study highlights the need to integrate public perceptions into the planning and management of IAPs and emphasises the importance of including ES assessments into the decision-making process, particularly in urban areas. Copyright © 2018 Elsevier Ltd. All rights reserved.

  6. Modelling of nuclear power plant decommissioning financing.

    PubMed

    Bemš, J; Knápek, J; Králík, T; Hejhal, M; Kubančák, J; Vašíček, J

    2015-06-01

    Costs related to the decommissioning of nuclear power plants create a significant financial burden for nuclear power plant operators. This article discusses the various methodologies employed by selected European countries for financing of the liabilities related to the nuclear power plant decommissioning. The article also presents methodology of allocation of future decommissioning costs to the running costs of nuclear power plant in the form of fee imposed on each megawatt hour generated. The application of the methodology is presented in the form of a case study on a new nuclear power plant with installed capacity 1000 MW. © The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  7. Enabling plant synthetic biology through genome engineering.

    PubMed

    Baltes, Nicholas J; Voytas, Daniel F

    2015-02-01

    Synthetic biology seeks to create new biological systems, including user-designed plants and plant cells. These systems can be employed for a variety of purposes, ranging from producing compounds of industrial or therapeutic value, to reducing crop losses by altering cellular responses to pathogens or climate change. To realize the full potential of plant synthetic biology, techniques are required that provide control over the genetic code - enabling targeted modifications to DNA sequences within living plant cells. Such control is now within reach owing to recent advances in the use of sequence-specific nucleases to precisely engineer genomes. We discuss here the enormous potential provided by genome engineering for plant synthetic biology. Copyright © 2014 Elsevier Ltd. All rights reserved.

  8. Fractionation of metal stable isotopes by higher plants

    USGS Publications Warehouse

    Von Blanckenburg, F.; Von Wiren, N.; Guelke, M.; Weiss, D.J.; Bullen, T.D.

    2009-01-01

    Higher plants induce chemical reactions in the rhizosphere, facilitating metal uptake by roots. Fractionation of the isotopes in nutrients such as calcium, iron, magnesium, and zinc produces a stable isotope composition in the plants that generally differs from that of the growth medium. Isotope fractionation also occurs during transport of the metals within most plants, but its extent depends on plant species and on the metal, in particular, on the metal's redox state and what ligand it is bound to. The metal stable isotope variations observed in plants create an isotope signature of life at the Earth's surface, contributing substantially to our understanding of metal cycling processes in the environment and in individual organisms.

  9. PlantDB – a versatile database for managing plant research

    PubMed Central

    Exner, Vivien; Hirsch-Hoffmann, Matthias; Gruissem, Wilhelm; Hennig, Lars

    2008-01-01

    Background Research in plant science laboratories often involves usage of many different species, cultivars, ecotypes, mutants, alleles or transgenic lines. This creates a great challenge to keep track of the identity of experimental plants and stored samples or seeds. Results Here, we describe PlantDB – a Microsoft® Office Access database – with a user-friendly front-end for managing information relevant for experimental plants. PlantDB can hold information about plants of different species, cultivars or genetic composition. Introduction of a concise identifier system allows easy generation of pedigree trees. In addition, all information about any experimental plant – from growth conditions and dates over extracted samples such as RNA to files containing images of the plants – can be linked unequivocally. Conclusion We have been using PlantDB for several years in our laboratory and found that it greatly facilitates access to relevant information. PMID:18182106

  10. Actin Cytoskeleton-Based Plant Synapse as Gravitransducer in the Transition Zone of the Root Apex

    NASA Astrophysics Data System (ADS)

    Baluska, Frantisek; Barlow, Peter; Volkmann, Dieter; Mancuso, Stefano

    The actin cytoskeleton was originally proposed to act as the signal transducer in the plant gravity sensory-motoric circuit. Surprisingly, however, several studies have documented that roots perfom gravisensing and gravitropism more effectively if exposed to diverse anti-F-actin drugs. Our study, using decapped maize root apices, has revealed that depolymerization of F-actin stimulates gravity perception in cells of the transition zone where root gravitropism is initiated (Mancuso et al. 2006). It has been proposed (Balǔka et al. 2005, 2009a) that s the non-growing adhesive end-poles, enriched with F-actin and myosin VIII, and active in endocytic recycling of both PIN transporters and cell wall pectins cross-linked with calcium and boron, act as the gravisensing domains, and that these impinge directly upon the root motoric responses via control of polar auxin transport. This model suggests that mechanical asymmetry at these plant synapses determines vectorial gravity-controlled auxin transport. Due to the gravity-imposed mechanical load upon the protoplast, a tensional stress is also imposed upon the plasma membrane of the physically lower synaptic cell pole. This stress is then relieved by shifting the endocytosis-exocytosis balance towards exocytosis (Balǔka et al. s 2005, 2009a,b). This `Synaptic Auxin Secretion' hypothesis does not conflict with the `Starch Statolith' hypothesis, which is based on amyloplast sedimentation. In fact, the `Synaptic Auxin Secretion' hypothesis has many elements which allow its unification with the Starch-Statolith model (Balǔka et al. 2005, 2009a,b). s References Balǔka F, Volkmann D, Menzel D (2005) Plant synapses: actin-based adhesion s domains for cell-to-cell communication. Trends Plant Sci 10: 106-111 Balǔka F, Schlicht M, s Wan Y-L, Burbach C, Volkmann D (2009a) Intracellular domains and polarity in root apices: from synaptic domains to plant neurobiology. Nova Acta Leopoldina 96: 103-122 Balǔka s F, Mancuso S, Volkmann D, Barlow PW (2009b) The 'root-brain' hypothesis of Charles and Francis Darwin: Revival after more than 125 years. Plant Signal Behav 4: 1121-1127 Mancuso S, Barlow PW, Volkmann D, Balǔka F (2006). Actin turnover-mediated gravity response in s maize root apices: gravitropism of decapped roots implicates gravisensing outside of the root cap. Plant Signal Behav 1: 52-58

  11. Knowledge-based object recognition for different morphological classes of plants

    NASA Astrophysics Data System (ADS)

    Brendel, Thorsten; Schwanke, Joerg; Jensch, Peter F.; Megnet, Roland

    1995-01-01

    Micropropagation of plants is done by cutting juvenile plants and placing them into special container-boxes with nutrient-solution where the pieces can grow up and be cut again several times. To produce high amounts of biomass it is necessary to do plant micropropagation by a robotic syshoot. In this paper we describe parts of the vision syshoot that recognizes plants and their particular cutting points. Therefore, it is necessary to extract elements of the plants and relations between these elements (for example root, shoot, leaf). Different species vary in their morphological appearance, variation is also immanent in plants of the same species. Therefore, we introduce several morphological classes of plants from that we expect same recognition methods. As a result of our work we present rules which help users to create specific algorithms for object recognition of plant species.

  12. Freeing Crop Genetics through the Open Source Seed Initiative

    PubMed Central

    Luby, Claire H.; Goldman, Irwin L.

    2016-01-01

    For millennia, seeds have been freely available to use for farming and plant breeding without restriction. Within the past century, however, intellectual property rights (IPRs) have threatened this tradition. In response, a movement has emerged to counter the trend toward increasing consolidation of control and ownership of plant germplasm. One effort, the Open Source Seed Initiative (OSSI, www.osseeds.org), aims to ensure access to crop genetic resources by embracing an open source mechanism that fosters exchange and innovation among farmers, plant breeders, and seed companies. Plant breeders across many sectors have taken the OSSI Pledge to create a protected commons of plant germplasm for future generations. PMID:27093567

  13. Freeing Crop Genetics through the Open Source Seed Initiative.

    PubMed

    Luby, Claire H; Goldman, Irwin L

    2016-04-01

    For millennia, seeds have been freely available to use for farming and plant breeding without restriction. Within the past century, however, intellectual property rights (IPRs) have threatened this tradition. In response, a movement has emerged to counter the trend toward increasing consolidation of control and ownership of plant germplasm. One effort, the Open Source Seed Initiative (OSSI, www.osseeds.org), aims to ensure access to crop genetic resources by embracing an open source mechanism that fosters exchange and innovation among farmers, plant breeders, and seed companies. Plant breeders across many sectors have taken the OSSI Pledge to create a protected commons of plant germplasm for future generations.

  14. Land-markings: 12 Journeys through 9/11 Living Memorials

    Treesearch

    Erika S. Svendsen; Lindsay K. Campbell

    2006-01-01

    Living memorials are spaces created, used, or reappropriated by people as they employ the landscape to memorialize individuals, places, and events. Ranging from single tree plantings, to the creation of new parks, to the rededication of existing forests, hundreds of groups across the country created a vast network of sites that continues to grow. "Land-markings:...

  15. In vivo monoubiquitination of anaplerotic phosphoenolpyruvate carboxylase occurs at Lys624 in germinating sorghum seeds.

    PubMed

    Ruiz-Ballesta, Isabel; Feria, Ana-Belén; Ni, Hong; She, Yi-Min; Plaxton, William Charles; Echevarría, Cristina

    2014-02-01

    Phosphoenolpyruvate carboxylase (PEPC; EC 4.1.1.31) is an important cytosolic regulatory enzyme that plays a pivotal role in numerous physiological processes in plants, including seed development and germination. Previous studies demonstrated the occurrence of immunoreactive PEPC polypeptides of ~110 kDa and 107 kDa (p110 and p107, respectively) on immunoblots of clarified extracts of germinating sorghum (Sorghum bicolor) seeds. In order to establish the biochemical basis for this observation, a 460 kDa PEPC heterotetramer composed of an equivalent ratio of p110 and p107 subunits was purified to near homogeneity from the germinated seeds. Mass spectrometry established that p110 and p107 are both encoded by the same plant-type PEPC gene (CP21), but that p107 was in vivo monoubiquitinated at Lys624 to form p110. This residue is absolutely conserved in vascular plant PEPCs and is proximal to a PEP-binding/catalytic domain. Anti-ubiquitin IgG immunodetected p110 but not p107, whereas incubation with a deubiquitinating enzyme (USP-2 core) efficiently converted p110 into p107, while relieving the enzyme's feedback inhibition by L-malate. Partial PEPC monoubiquitination was also detected during sorghum seed development. It is apparent that monoubiquitination at Lys624 is opposed to phosphorylation at Ser7 in terms of regulating the catalytic activity of sorghum seed PEPC. PEPC monoubiquitination is hypothesized to fine-tune anaplerotic carbon flux according to the cell's immediate physiological requirements for tricarboxylic acid cycle intermediates needed in support of biosynthesis and carbon-nitrogen interactions.

  16. Herbal medicine for sports: a review.

    PubMed

    Sellami, Maha; Slimeni, Olfa; Pokrywka, Andrzej; Kuvačić, Goran; D Hayes, Lawrence; Milic, Mirjana; Padulo, Johnny

    2018-01-01

    The use of herbal medicinal products and supplements has increased during last decades. At present, some herbs are used to enhance muscle strength and body mass. Emergent evidence suggests that the health benefits from plants are attributed to their bioactive compounds such as Polyphenols, Terpenoids, and Alkaloids which have several physiological effects on the human body. At times, manufacturers launch numerous products with banned ingredient inside with inappropriate amounts or fake supplement inducing harmful side effect. Unfortunately up to date, there is no guarantee that herbal supplements are safe for anyone to use and it has not helped to clear the confusion surrounding the herbal use in sport field especially. Hence, the purpose of this review is to provide guidance on the efficacy and side effect of most used plants in sport. We have identified plants according to the following categories: Ginseng, alkaloids, and other purported herbal ergogenics such as Tribulus Terrestris , Cordyceps Sinensis. We found that most herbal supplement effects are likely due to activation of the central nervous system via stimulation of catecholamines. Ginseng was used as an endurance performance enhancer, while alkaloids supplementation resulted in improvements in sprint and cycling intense exercises. Despite it is prohibited, small amount of ephedrine was usually used in combination with caffeine to enhance muscle strength in trained individuals. Some other alkaloids such as green tea extracts have been used to improve body mass and composition in athletes. Other herb (i.e. Rhodiola, Astragalus) help relieve muscle and joint pain, but results about their effects on exercise performance are missing.

  17. In vivo monoubiquitination of anaplerotic phosphoenolpyruvate carboxylase occurs at Lys624 in germinating sorghum seeds

    PubMed Central

    Echevarría, Cristina

    2014-01-01

    Phosphoenolpyruvate carboxylase (PEPC; EC 4.1.1.31) is an important cytosolic regulatory enzyme that plays a pivotal role in numerous physiological processes in plants, including seed development and germination. Previous studies demonstrated the occurrence of immunoreactive PEPC polypeptides of ~110kDa and 107kDa (p110 and p107, respectively) on immunoblots of clarified extracts of germinating sorghum (Sorghum bicolor) seeds. In order to establish the biochemical basis for this observation, a 460kDa PEPC heterotetramer composed of an equivalent ratio of p110 and p107 subunits was purified to near homogeneity from the germinated seeds. Mass spectrometry established that p110 and p107 are both encoded by the same plant-type PEPC gene (CP21), but that p107 was in vivo monoubiquitinated at Lys624 to form p110. This residue is absolutely conserved in vascular plant PEPCs and is proximal to a PEP-binding/catalytic domain. Anti-ubiquitin IgG immunodetected p110 but not p107, whereas incubation with a deubiquitinating enzyme (USP-2 core) efficiently converted p110 into p107, while relieving the enzyme’s feedback inhibition by l-malate. Partial PEPC monoubiquitination was also detected during sorghum seed development. It is apparent that monoubiquitination at Lys624 is opposed to phosphorylation at Ser7 in terms of regulating the catalytic activity of sorghum seed PEPC. PEPC monoubiquitination is hypothesized to fine-tune anaplerotic carbon flux according to the cell’s immediate physiological requirements for tricarboxylic acid cycle intermediates needed in support of biosynthesis and carbon–nitrogen interactions. PMID:24288181

  18. Acute effects of Sceletium tortuosum (Zembrin), a dual 5-HT reuptake and PDE4 inhibitor, in the human amygdala and its connection to the hypothalamus.

    PubMed

    Terburg, David; Syal, Supriya; Rosenberger, Lisa A; Heany, Sarah; Phillips, Nicole; Gericke, Nigel; Stein, Dan J; van Honk, Jack

    2013-12-01

    The South African endemic plant Sceletium tortuosum has a long history of traditional use as a masticatory and medicine by San and Khoikhoi people and subsequently by European colonial farmers as a psychotropic in tincture form. Over the past decade, the plant has attracted increasing attention for its possible applications in promoting a sense of wellbeing and relieving stress in healthy individuals and for treating clinical anxiety and depression. The pharmacological actions of a standardized extract of the plant (Zembrin) have been reported to be dual PDE4 inhibition and 5-HT reuptake inhibition, a combination that has been argued to offer potential therapeutic advantages. Here we tested the acute effects of Zembrin administration in a pharmaco-fMRI study focused on anxiety-related activity in the amygdala and its connected neurocircuitry. In a double-blind, placebo-controlled, cross-over design, 16 healthy participants were scanned during performance in a perceptual-load and an emotion-matching task. Amygdala reactivity to fearful faces under low perceptual load conditions was attenuated after a single 25 mg dose of Zembrin. Follow-up connectivity analysis on the emotion-matching task showed that amygdala-hypothalamus coupling was also reduced. These results demonstrate, for the first time, the attenuating effects of S. tortuosum on the threat circuitry of the human brain and provide supporting evidence that the dual 5-HT reuptake inhibition and PDE4 inhibition of this extract might have anxiolytic potential by attenuating subcortical threat responsivity.

  19. Acute Effects of Sceletium tortuosum (Zembrin), a Dual 5-HT Reuptake and PDE4 Inhibitor, in the Human Amygdala and its Connection to the Hypothalamus

    PubMed Central

    Terburg, David; Syal, Supriya; Rosenberger, Lisa A; Heany, Sarah; Phillips, Nicole; Gericke, Nigel; Stein, Dan J; van Honk, Jack

    2013-01-01

    The South African endemic plant Sceletium tortuosum has a long history of traditional use as a masticatory and medicine by San and Khoikhoi people and subsequently by European colonial farmers as a psychotropic in tincture form. Over the past decade, the plant has attracted increasing attention for its possible applications in promoting a sense of wellbeing and relieving stress in healthy individuals and for treating clinical anxiety and depression. The pharmacological actions of a standardized extract of the plant (Zembrin) have been reported to be dual PDE4 inhibition and 5-HT reuptake inhibition, a combination that has been argued to offer potential therapeutic advantages. Here we tested the acute effects of Zembrin administration in a pharmaco-fMRI study focused on anxiety-related activity in the amygdala and its connected neurocircuitry. In a double-blind, placebo-controlled, cross-over design, 16 healthy participants were scanned during performance in a perceptual-load and an emotion-matching task. Amygdala reactivity to fearful faces under low perceptual load conditions was attenuated after a single 25 mg dose of Zembrin. Follow-up connectivity analysis on the emotion-matching task showed that amygdala–hypothalamus coupling was also reduced. These results demonstrate, for the first time, the attenuating effects of S. tortuosum on the threat circuitry of the human brain and provide supporting evidence that the dual 5-HT reuptake inhibition and PDE4 inhibition of this extract might have anxiolytic potential by attenuating subcortical threat responsivity. PMID:23903032

  20. Efficient modification of floral traits by heavy-ion beam irradiation on transgenic Torenia.

    PubMed

    Ohtsubo, Norihiro; Sasaki, Katsutomo; Aida, Ryutaro; Ryuto, Hiromichi; Ichida, Hiroyuki; Hayashi, Yoriko; Abe, Tomoko

    2012-01-01

    While heavy-ion beam irradiation is becoming popular technology for mutation breeding in Japan, the combination with genetic manipulation makes it more convenient to create greater variation in plant phenotypes. We have succeeded in producing over 200 varieties of transgenic torenia (Torenia fournieri Lind.) from over 2,400 regenerated plants by this procedure in only 2 years. Mutant phenotypes were observed mainly in flowers and showed wide variation in colour and shape. Higher mutation rates in the transgenics compared to those in wild type indicate the synergistic effect of genetic manipulation and heavy-ion beam irradiation, which might be advantageous to create greater variation in floral traits.

  1. Root Systems of Individual Plants, and the Biotic and Abiotic Factors Controlling Their Depth and Distribution: a Synthesis Using a Global Database.

    NASA Astrophysics Data System (ADS)

    Tumber-Davila, S. J.; Schenk, H. J.; Jackson, R. B.

    2017-12-01

    This synthesis examines plant rooting distributions globally, by doubling the number of entries in the Root Systems of Individual Plants database (RSIP) created by Schenk and Jackson. Root systems influence many processes, including water and nutrient uptake and soil carbon storage. Root systems also mediate vegetation responses to changing climatic and environmental conditions. Therefore, a collective understanding of the importance of rooting systems to carbon sequestration, soil characteristics, hydrology, and climate, is needed. Current global models are limited by a poor understanding of the mechanisms affecting rooting, carbon stocks, and belowground biomass. This improved database contains an extensive bank of records describing the rooting system of individual plants, as well as detailed information on the climate and environment from which the observations are made. The expanded RSIP database will: 1) increase our understanding of rooting depths, lateral root spreads and above and belowground allometry; 2) improve the representation of plant rooting systems in Earth System Models; 3) enable studies of how climate change will alter and interact with plant species and functional groups in the future. We further focus on how plant rooting behavior responds to variations in climate and the environment, and create a model that can predict rooting behavior given a set of environmental conditions. Preliminary results suggest that high potential evapotranspiration and seasonality of precipitation are indicative of deeper rooting after accounting for plant growth form. When mapping predicted deep rooting by climate, we predict deepest rooting to occur in equatorial South America, Africa, and central India.

  2. LEGO® Bricks as Building Blocks for Centimeter-Scale Biological Environments: The Case of Plants

    PubMed Central

    Lind, Kara R.; Sizmur, Tom; Benomar, Saida; Miller, Anthony; Cademartiri, Ludovico

    2014-01-01

    LEGO bricks are commercially available interlocking pieces of plastic that are conventionally used as toys. We describe their use to build engineered environments for cm-scale biological systems, in particular plant roots. Specifically, we take advantage of the unique modularity of these building blocks to create inexpensive, transparent, reconfigurable, and highly scalable environments for plant growth in which structural obstacles and chemical gradients can be precisely engineered to mimic soil. PMID:24963716

  3. LEGO® bricks as building blocks for centimeter-scale biological environments: the case of plants.

    PubMed

    Lind, Kara R; Sizmur, Tom; Benomar, Saida; Miller, Anthony; Cademartiri, Ludovico

    2014-01-01

    LEGO bricks are commercially available interlocking pieces of plastic that are conventionally used as toys. We describe their use to build engineered environments for cm-scale biological systems, in particular plant roots. Specifically, we take advantage of the unique modularity of these building blocks to create inexpensive, transparent, reconfigurable, and highly scalable environments for plant growth in which structural obstacles and chemical gradients can be precisely engineered to mimic soil.

  4. CRISPR: From Prokaryotic Immune Systems to Plant Genome Editing Tools.

    PubMed

    Bandyopadhyay, Anindya; Mazumdar, Shamik; Yin, Xiaojia; Quick, William Paul

    2017-01-01

    The clustered regularly interspaced short palindromic repeats (CRISPR) system is a prokaryotic adaptive immune system that has the ability to identify specific locations on the bacteriophage (phage) genome to create breaks in it, and internalize the phage genome fragments in its own genome as CRISPR arrays for memory-dependent resistance. Although CRISPR has been used in the dairy industry for a long time, it recently gained importance in the field of genome editing because of its ability to precisely target locations in a genome. This system has further been modified to locate and target any region of a genome of choice due to modifications in the components of the system. By changing the nucleotide sequence of the 20-nucleotide target sequence in the guide RNA, targeting any location is possible. It has found an application in the modification of plant genomes with its ability to generate mutations and insertions, thus helping to create new varieties of plants. With the ability to introduce specific sequences into the plant genome after cleavage by the CRISPR system and subsequent DNA repair through homology-directed repair (HDR), CRISPR ensures that genome editing can be successfully applied in plants, thus generating stronger and more improved traits. Also, the use of the CRISPR editing system can generate plants that are transgene-free and have mutations that are stably inherited, thus helping to circumvent current GMO regulations.

  5. Intracutaneous sterile water injections do not relieve pain in cervicogenic headache.

    PubMed

    Sand, T; Bovim, G; Helde, G

    1992-11-01

    Intracutaneous sterile water injections have been reported to relieve acute labor pain and cervical pain in whip-lash patients. A double blind cross-over trial has presently been conducted in 10 women with cervicogenic headache in order to investigate whether sterile water injections were effective in this disorder. No benefit was observed for either treatment (isotonic saline or sterile water), neither on pain during the first 14 days nor on neck mobility. We conclude that intracutaneous sterile water injections is not effective in cervicogenic headache.

  6. Simultaneous knockdown of six non-family genes using a single synthetic RNAi fragment in Arabidopsis thaliana

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Czarnecki, Olaf; Bryan, Anthony C.; Jawdy, Sara S.

    Genetic engineering of plants that results in successful establishment of new biochemical or regulatory pathways requires stable introduction of one or more genes into the plant genome. It might also be necessary to down-regulate or turn off expression of endogenous genes in order to reduce activity of competing pathways. An established way to knockdown gene expression in plants is expressing a hairpin-RNAi construct, eventually leading to degradation of a specifically targeted mRNA. Knockdown of multiple genes that do not share homologous sequences is still challenging and involves either sophisticated cloning strategies to create vectors with different serial expression constructs ormore » multiple transformation events that is often restricted by a lack of available transformation markers. Synthetic RNAi fragments were assembled in yeast carrying homologous sequences to six or seven non-family genes and introduced into pAGRIKOLA. Transformation of Arabidopsis thaliana and subsequent expression analysis of targeted genes proved efficient knockdown of all target genes. In conclusion, we present a simple and cost-effective method to create constructs to simultaneously knockdown multiple non-family genes or genes that do not share sequence homology. The presented method can be applied in plant and animal synthetic biology as well as traditional plant and animal genetic engineering.« less

  7. Crop calendars for the US, USSR, and Canada in support of the early warning project

    NASA Technical Reports Server (NTRS)

    Hodges, T.; Sestak, M. L.; Trenchard, M. H. (Principal Investigator)

    1980-01-01

    New crop calendars are produced for U.S. regions where several years of periodic growth stage observations are available on a CRD basis. Preexisting crop calendars from the LACIE are also collected as are U.S. crop calendars currently being created for the Foreign Commodities Production Forecast project. For the U.S.S.R. and Canada, no new crop calendars are created because no new data are available. Instead, LACIE crop calendars are compared against simulated normal daily temperatures and against the Robertson wheat and Williams barley phenology models run on the simulated normal temperatures. Severe inconsistencies are noted and discussed. For the U.S.S.R., spring and fall planting dates can probably be estimated accurately from satellite or meteorological data. For the starter model problem, the Feyerherm spring wheat model is recommended for spring planted small grains, and the results of an analysis are presented. For fall planted small grains, use of normal planting dates supplemented by spectral observation of an early stage is recommended. The importance of nonmeteorological factors as they pertain to meteorological factors in determining fall planting is discussed. Crop calendar data available at the Johnson Space Center for the U.S., U.S.S.R., Canada, and other countries are inventoried.

  8. Gene Networks Involved in Hormonal Control of Root Development in Arabidopsis thaliana: A Framework for Studying Its Disturbance by Metal Stress

    PubMed Central

    De Smet, Stefanie; Cuypers, Ann; Vangronsveld, Jaco; Remans, Tony

    2015-01-01

    Plant survival under abiotic stress conditions requires morphological and physiological adaptations. Adverse soil conditions directly affect root development, although the underlying mechanisms remain largely to be discovered. Plant hormones regulate normal root growth and mediate root morphological responses to abiotic stress. Hormone synthesis, signal transduction, perception and cross-talk create a complex network in which metal stress can interfere, resulting in root growth alterations. We focus on Arabidopsis thaliana, for which gene networks in root development have been intensively studied, and supply essential terminology of anatomy and growth of roots. Knowledge of gene networks, mechanisms and interactions related to the role of plant hormones is reviewed. Most knowledge has been generated for auxin, the best-studied hormone with a pronounced primary role in root development. Furthermore, cytokinins, gibberellins, abscisic acid, ethylene, jasmonic acid, strigolactones, brassinosteroids and salicylic acid are discussed. Interactions between hormones that are of potential importance for root growth are described. This creates a framework that can be used for investigating the impact of abiotic stress factors on molecular mechanisms related to plant hormones, with the limited knowledge of the effects of the metals cadmium, copper and zinc on plant hormones and root development included as case example. PMID:26287175

  9. Simultaneous knockdown of six non-family genes using a single synthetic RNAi fragment in Arabidopsis thaliana

    DOE PAGES

    Czarnecki, Olaf; Bryan, Anthony C.; Jawdy, Sara S.; ...

    2016-02-17

    Genetic engineering of plants that results in successful establishment of new biochemical or regulatory pathways requires stable introduction of one or more genes into the plant genome. It might also be necessary to down-regulate or turn off expression of endogenous genes in order to reduce activity of competing pathways. An established way to knockdown gene expression in plants is expressing a hairpin-RNAi construct, eventually leading to degradation of a specifically targeted mRNA. Knockdown of multiple genes that do not share homologous sequences is still challenging and involves either sophisticated cloning strategies to create vectors with different serial expression constructs ormore » multiple transformation events that is often restricted by a lack of available transformation markers. Synthetic RNAi fragments were assembled in yeast carrying homologous sequences to six or seven non-family genes and introduced into pAGRIKOLA. Transformation of Arabidopsis thaliana and subsequent expression analysis of targeted genes proved efficient knockdown of all target genes. In conclusion, we present a simple and cost-effective method to create constructs to simultaneously knockdown multiple non-family genes or genes that do not share sequence homology. The presented method can be applied in plant and animal synthetic biology as well as traditional plant and animal genetic engineering.« less

  10. Controlling attachment and growth of Listeria monocytogenes in PVC model floor drains using a peroxide chemical, chitosan/arginine or heat

    USDA-ARS?s Scientific Manuscript database

    Listeria monocytogenes enters a poultry further processing plant with raw product and colonizes the plant as a resident in floor drains. We have shown that L. monocytogenes can escape floor drains, becoming airborne during wash down, creating potential for contamination of fully cooked product. Li...

  11. Creating a Successful Citizen Science Model to Detect and Report Invasive Species

    ERIC Educational Resources Information Center

    Gallo, Travis; Waitt, Damon

    2011-01-01

    The Invaders of Texas program is a successful citizen science program in which volunteers survey and monitor invasive plants throughout Texas. Invasive plants are being introduced at alarming rates, and our limited knowledge about their distribution is a major cause for concern. The Invaders of Texas program trains citizen scientists to detect the…

  12. Resistance to Phakopsora pachyrhizi in soybean PI 587905 maps to the Rpp1 locus and exhibits variable dominance associated with plant ontogeny

    USDA-ARS?s Scientific Manuscript database

    Soybean rust, caused by Phakopsora pachyrhizi Sydow, results in significant yield loss worldwide. Soybean accession PI 587905, previously identified as having resistance to P. pachyrhizi, was used to create two independent populations (F2 plants and F2-derived F3 lines) segregating for resistance. ...

  13. Creating a Schoolyard Mini-Garden

    ERIC Educational Resources Information Center

    Garcia-Ruiz, Francisca

    2009-01-01

    The creation of schoolyard gardens is a growing movement in the United States and around the world (Ballard, Tong, and Usher 1998; Pope 1998; Lewis 2004). It brings together all of the features of authentic hands-on science: Students can collect data on plant growth, observe the plant and animal interactions in the garden, and acquire a sense of…

  14. Fantasy Seed Company: A Role Playing Game for Plant Breeding Courses

    ERIC Educational Resources Information Center

    Hague, Steve S.

    2011-01-01

    Understanding plant breeding as well as procedures and issues of seed companies are skills students studying agronomy need to acquire. Simulation games can be effective teaching tools in developing higher-order thinking skills of students. The "Fantasy Seed Company" game was developed to create motivated learners by allowing students to run a mock…

  15. Tree thinning treatments alter soil properties, arbuscular mycorrhizal fungi and understory plant communities

    Treesearch

    Suzanne M. Neal

    2007-01-01

    Forest management practices designed to reduce fire risk, particularly thinning followed by burning slash piles, can cause below ground disturbance that creates favorable conditions for exotic plant species. Newer fuel-reduction methods, such as mechanical mastication are being examined as potential alternatives to the burning of slash piles. We compared soil...

  16. Incorporating plant mortality and recruitment into rangeland management and assessment

    Treesearch

    Tony Svejcar; Jeremy James; Stuart Hardegree; Roger Sheley

    2014-01-01

    Rangeland management is largely focused on managing vegetation change. Objectives may include managing against change if the desired vegetation is in place, or attempting to create a shift in vegetation if the desired plant community is not present. There is a rich body of research documenting influences of disturbance and management on rangeland vegetation. However,...

  17. Integrative functional analyses using rainbow trout selected for tolerance to plant diets reveal nutrigenomic signatures for soy utilization without the concurrence of enteritis

    USDA-ARS?s Scientific Manuscript database

    Finding suitable alternative protein sources for diets of carnivorous fish species remains a major concern for sustainable aquaculture. Through genetic selection, we created a strain of rainbow trout that outperforms parental lines in utilizing an all-plant protein diet and does not develop enteriti...

  18. Plant succession on the Mount St. Helens debris-avalanche deposit and the role of non-native species

    USDA-ARS?s Scientific Manuscript database

    The debris-avalanche deposit is one of the most severely disturbed areas created by the 1980 eruption of Mount St. Helens, with little survival of a few plant fragments, and primary succession mostly being initiated by the seeds dispersed onto the newly emplaced material. Vegetation changes on the d...

  19. 76 FR 67581 - Importation of Bromeliad Plants in Growing Media From Belgium, Denmark, and the Netherlands

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-02

    ... marketing channels, with retailers able to buy mature plants directly from European suppliers rather than... to the extent that they would be eliminated from the marketing chain, the commenter stated that we... wholesale nurseries, but there may also be jobs created as other businesses expand due to new marketing...

  20. Software for computing plant biomass—BIOPAK users guide.

    Treesearch

    Joseph E. Means; Heather A. Hansen; Greg J. Koerper; Paul B Alaback; Mark W. Klopsch

    1994-01-01

    BIOPAK is a menu-driven package of computer programs for IBM-compatible personal computers that calculates the biomass, area, height, length, or volume of plant components (leaves, branches, stem, crown, and roots). The routines were written in FoxPro, Fortran, and C.BIOPAK was created to facilitate linking of a diverse array of vegetation datasets with the...

  1. Partial automation of database processing of simulation outputs from L-systems models of plant morphogenesis.

    PubMed

    Chen, Yi- Ping Phoebe; Hanan, Jim

    2002-01-01

    Models of plant architecture allow us to explore how genotype environment interactions effect the development of plant phenotypes. Such models generate masses of data organised in complex hierarchies. This paper presents a generic system for creating and automatically populating a relational database from data generated by the widely used L-system approach to modelling plant morphogenesis. Techniques from compiler technology are applied to generate attributes (new fields) in the database, to simplify query development for the recursively-structured branching relationship. Use of biological terminology in an interactive query builder contributes towards making the system biologist-friendly.

  2. An operation support expert system based on on-line dynamics simulation and fuzzy reasoning for startup schedule optimization in fossil power plants

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Matsumoto, H.; Eki, Y.; Kaji, A.

    1993-12-01

    An expert system which can support operators of fossil power plants in creating the optimum startup schedule and executing it accurately is described. The optimum turbine speed-up and load-up pattern is obtained through an iterative manner which is based on fuzzy resonating using quantitative calculations as plant dynamics models and qualitative knowledge as schedule optimization rules with fuzziness. The rules represent relationships between stress margins and modification rates of the schedule parameters. Simulations analysis proves that the system provides quick and accurate plant startups.

  3. Estimate for interstage water injection in air compressor incorporated into gas-turbine cycles and combined power plants cycles

    NASA Astrophysics Data System (ADS)

    Kler, A. M.; Zakharov, Yu. B.; Potanina, Yu. M.

    2017-05-01

    The objects of study are the gas turbine (GT) plant and combined cycle power plant (CCPP) with opportunity for injection between the stages of air compressor. The objective of this paper is technical and economy optimization calculations for these classes of plants with water interstage injection. The integrated development environment "System of machine building program" was a tool for creating the mathematic models for these classes of power plants. Optimization calculations with the criterion of minimum for specific capital investment as a function of the unit efficiency have been carried out. For a gas-turbine plant, the economic gain from water injection exists for entire range of power efficiency. For the combined cycle plant, the economic benefit was observed only for a certain range of plant's power efficiency.

  4. Novel approaches and tools to reduce environmental impacts in agrosystems

    NASA Astrophysics Data System (ADS)

    De Cesare, Fabrizio; Macagnano, Antonella

    2017-04-01

    The world population is estimated to increase until about 9 billion of people in 2050. The contemporary limitation and increased degradation of land areas for agricultural uses have been posing serious problems to the management of food production. In the last century, an excessive use of agrochemicals (fertilisers and pesticides) in intensive agrosystems to improve crop yields and match human nutritional needs have caused great impact on the soil ecosystems (properties and biodiversity) and people's health. Consequently, more ecofriendly solutions (e.g. integrated crop and pest management - ICPM - and organic farming) have started to be pursued by scientists, public opinion and governments. In nature, several strategies and mechanisms have been evolved to provide nutrients to plants and defend them from pest and pathogen attacks. They consist in modifications of the environment surrounding plants (e.g. acidification), or the production of compounds for plant protection (e.g. biopesticides). As a consequence, farmers have often adopted practices to modify soil properties according to the crop needs for nutrients to facilitate their mobilisation and uptake by plants. Other more sophisticated natural strategies involve interactions between plant, soil and microorganisms, so that plants attract beneficial organisms that assist them: i) to mobilise and collect nutrients upon symbiotic or non-symbiotic relationships; ii) to suppress pests and pathogens by predation or the secretion of biocidal compounds; iii) to stimulate plant growth (regulators). In recent studies, we have created nanomaterial-based tools to: i) support plant growth; ii) detecting soil metabolic activities and quality; iii) degrading pollutants in environments; iv) detecting and monitoring pollutants in environments. Such nanostructured tools have been generated employing a nanotechnology capable of producing nanofibres under an electric field, called electrospinning. By electrospinning, it is possible to obtain fibres in the range of tens of nanometres to few micrometres to create 2D and 3D fibrous scaffolds. These nanostructures are characterised by considerable porosity and large surface area. The further possibility to use a variety of materials (inorganic and organic) to produce pure and composite polymers enlarge the possible properties of the resulting nanostructures for a multitude of applications (medicine, environment, healthcare, textile, energy, etc.) considerably. The nanofibrous scaffolds we created on purpose were specifically aimed at i) preventing micronutrient deficiency in plants (iron mobilisation mediated by siderophore release followed by plant uptake); ii) developing PGPR-biofilms stimulating plant growth by hormones and mobilising nutrients (phosphorus) and micronutrients (iron); iii) developing biocontrol fungal biofilms protecting plants from diseases by suppressing phytopathogen activity; iv) removing organic xenobiotics by adsorption and degradation mechanisms, thus limiting their environmental and health impact; v) developing sensing systems to detect xenobiotics, monitor their degradation and assess holistic soil metabolic activity.

  5. Carbon sequestration in two created riverine wetlands in the midwestern United States.

    PubMed

    Bernal, Blanca; Mitsch, William J

    2013-07-01

    Wetlands have the ability to accumulate significant amounts of carbon (C) and thus could provide an effective approach to mitigate greenhouse gas accumulation in the atmosphere. Wetland hydrology, age, and management can affect primary productivity, decomposition, and ultimately C sequestration in riverine wetlands, but these aspects of wetland biogeochemistry have not been adequately investigated, especially in created wetlands. In this study we investigate the ability of created freshwater wetlands to sequester C by determining the sediment accretion and soil C accumulation of two 15-yr-old created wetlands in central Ohio-one planted and one naturally colonized. We measured the amount of sediment and soil C accumulated over the parent material and found that these created wetlands accumulated an average of 242 g C m yr, 70% more than a similar natural wetland in the region and 26% more than the rate estimated for these same wetlands 5 yr before this study. The C sequestration of the naturally colonized wetland was 22% higher than that of the planted wetland (267 ± 17 vs. 219 ± 15 g C m yr, respectively). Soil C accrual accounted for 66% of the aboveground net primary productivity on average. Open water communities had the highest C accumulation rates in both wetlands. This study shows that created wetlands can be natural, cost-effective tools to sequester C to mitigate the effect of greenhouse gas emissions. Copyright © by the American Society of Agronomy, Crop Science Society of America, and Soil Science Society of America, Inc.

  6. Computer modelling of technogenic thermal pollution zones in large water bodies

    NASA Astrophysics Data System (ADS)

    Parshakova, Ya N.; Lyubimova, T. P.

    2018-01-01

    In the present work, the thermal pollution zones created due to discharge of heated water from thermal power plants are investigated using the example of the Permskaya Thermal Power Plant (Permskaya TPP or Permskaya GRES), which is one of the largest thermal power plants in Europe. The study is performed for different technological and hydrometeorological conditions. Since the vertical temperature distribution in such wastewater reservoirs is highly inhomogeneous, the computations are performed in the framework of 3D model.

  7. New research discovery may mean less radioactive contamination, safer nuclear power plants

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Murph, S.

    Murph has now made another nanoparticle breakthrough that could benefit various work environments such as nuclear power plants. Murph and her team have created nanoparticle treated stainless steel filters that are capable to capturing radioactive vapor materials. Just like air filters capture dust and dirt, these filters are capable of capturing large amounts of radioactive vapors. The new research may one day mean that nuclear power plant workers, and other workers in related fields, will have a safer working environment.

  8. Ecology: 'Devil's gardens' bedevilled by ants.

    PubMed

    Frederickson, Megan E; Greene, Michael J; Gordon, Deborah M

    2005-09-22

    'Devil's gardens' are large stands of trees in the Amazonian rainforest that consist almost entirely of a single species, Duroia hirsuta, and, according to local legend, are cultivated by an evil forest spirit. Here we show that the ant Myrmelachista schumanni, which nests in D. hirsuta stems, creates devil's gardens by poisoning all plants except its host plants with formic acid. By killing these other plants, M. schumanni provides its colonies with abundant nest sites--a long-lasting benefit as colonies can live for 800 years.

  9. Plant-Based Dietary Patterns and Incidence of Type 2 Diabetes in US Men and Women: Results from Three Prospective Cohort Studies

    PubMed Central

    Satija, Ambika; Bhupathiraju, Shilpa N.; Rimm, Eric B.; Spiegelman, Donna; Chiuve, Stephanie E.; Borgi, Lea; Willett, Walter C.; Manson, JoAnn E.; Sun, Qi; Hu, Frank B.

    2016-01-01

    Background Plant-based diets have been recommended to reduce the risk of type 2 diabetes (T2D). However, not all plant foods are necessarily beneficial. We examined the association of an overall plant-based diet and hypothesized healthful and unhealthful versions of a plant-based diet with T2D incidence in three prospective cohort studies in the US. Methods and Findings We included 69,949 women from the Nurses’ Health Study (1984–2012), 90,239 women from the Nurses’ Health Study 2 (1991–2011), and 40,539 men from the Health Professionals Follow-Up Study (1986–2010), free of chronic diseases at baseline. Dietary data were collected every 2–4 y using a semi-quantitative food frequency questionnaire. Using these data, we created an overall plant-based diet index (PDI), where plant foods received positive scores, while animal foods (animal fats, dairy, eggs, fish/seafood, poultry/red meat, miscellaneous animal-based foods) received reverse scores. We also created a healthful plant-based diet index (hPDI), where healthy plant foods (whole grains, fruits, vegetables, nuts, legumes, vegetable oils, tea/coffee) received positive scores, while less healthy plant foods (fruit juices, sweetened beverages, refined grains, potatoes, sweets/desserts) and animal foods received reverse scores. Lastly, we created an unhealthful plant-based diet index (uPDI) by assigning positive scores to less healthy plant foods and reverse scores to healthy plant foods and animal foods. We documented 16,162 incident T2D cases during 4,102,369 person-years of follow-up. In pooled multivariable-adjusted analysis, both PDI and hPDI were inversely associated with T2D (PDI: hazard ratio [HR] for extreme deciles 0.51, 95% CI 0.47–0.55, p trend < 0.001; hPDI: HR for extreme deciles 0.55, 95% CI 0.51–0.59, p trend < 0.001). The association of T2D with PDI was considerably attenuated when we additionally adjusted for body mass index (BMI) categories (HR 0.80, 95% CI 0.74–0.87, p trend < 0.001), while that with hPDI remained largely unchanged (HR 0.66, 95% CI 0.61–0.72, p trend < 0.001). uPDI was positively associated with T2D even after BMI adjustment (HR for extreme deciles 1.16, 95% CI 1.08–1.25, p trend < 0.001). Limitations of the study include self-reported diet assessment, with the possibility of measurement error, and the potential for residual or unmeasured confounding given the observational nature of the study design. Conclusions Our study suggests that plant-based diets, especially when rich in high-quality plant foods, are associated with substantially lower risk of developing T2D. This supports current recommendations to shift to diets rich in healthy plant foods, with lower intake of less healthy plant and animal foods. PMID:27299701

  10. Plant signalling: the opportunities and dangers of chemical communication.

    PubMed

    Adler, Frederick R

    2011-04-23

    The notion of chemical communication between plants and other organisms has gone from being viewed as a fringe idea to an accepted ecological phenomenon only recently. An Organized Oral Session at the August 2010 Ecological Society of America meeting in Pittsburgh examined the role of plant signalling both within and between plants, with speakers addressing the remarkably wide array of effects that plant signals have on plant physiology, species interactions and entire communities. In addition to the familiar way that plants communicate with mutualists like pollinators and fruit dispersers through both chemical and visual cues, speakers at this session described how plants communicate with themselves, with each other, with herbivores and with predators of those herbivores. These plant signals create a complex odour web superimposed upon the more classical food web itself, with its own dynamics in the face of exotic species and rapid community assembly and disassembly.

  11. Landscapes of facilitation: how self-organized patchiness of aquatic macrophytes promotes diversity in streams.

    PubMed

    Cornacchia, Loreta; van de Koppel, Johan; van der Wal, Daphne; Wharton, Geraldene; Puijalon, Sara; Bouma, Tjeerd J

    2018-04-01

    Spatial heterogeneity plays a crucial role in the coexistence of species. Despite recognition of the importance of self-organization in creating environmental heterogeneity in otherwise uniform landscapes, the effects of such self-organized pattern formation in promoting coexistence through facilitation are still unknown. In this study, we investigated the effects of pattern formation on species interactions and community spatial structure in ecosystems with limited underlying environmental heterogeneity, using self-organized patchiness of the aquatic macrophyte Callitriche platycarpa in streams as a model system. Our theoretical model predicted that pattern formation in aquatic vegetation - due to feedback interactions between plant growth, water flow and sedimentation processes - could promote species coexistence, by creating heterogeneous flow conditions inside and around the plant patches. The spatial plant patterns predicted by our model agreed with field observations at the reach scale in naturally vegetated rivers, where we found a significant spatial aggregation of two macrophyte species around C. platycarpa. Field transplantation experiments showed that C. platycarpa had a positive effect on the growth of both beneficiary species, and the intensity of this facilitative effect was correlated with the heterogeneous hydrodynamic conditions created within and around C. platycarpa patches. Our results emphasize the importance of self-organized patchiness in promoting species coexistence by creating a landscape of facilitation, where new niches and facilitative effects arise in different locations. Understanding the interplay between competition and facilitation is therefore essential for successful management of biodiversity in many ecosystems. © 2018 The Authors Ecology published by Wiley Periodicals, Inc. on behalf of Ecological Society of America.

  12. AMPAkines Target the Nucleus Accumbens to Relieve Postoperative Pain

    PubMed Central

    Su, Chen; Lin, Hau Yeuh; Yang, Runtao; Xu, Duo; Lee, Michelle; Pawlak, Natalie; Norcini, Monica; Sideris, Alexandra; Recio-Pinto, Esperanza; Huang, Dong; Wang, Jing

    2016-01-01

    Background AMPAkines augment the function of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors in the brain to increase excitatory outputs. These drugs are known to relieve persistent pain. However, their role in acute pain is unknown. Furthermore, a specific molecular and anatomic target for these novel analgesics remains elusive. Methods We studied the analgesic role of an AMPAkine, CX546, in a rat paw incision (PI) model of acute postoperative pain. We measured the effect of AMPAkines on sensory as well as depressive symptoms of pain using mechanical hypersensitivity and forced swim tests. We asked whether AMPA receptors in the nucleus accumbens (NAc), a key node in the brain's reward and pain circuitry, can be a target for AMPAkine analgesia. Results Systemic administration of CX546 (n=13), compared with control (n=13), reduced mechanical hypersensitivity (50% withdrawal threshold of 6.05±1.30g (mean±SEM) vs. 0.62±0.13g), and it reduced depressive features of pain by decreasing immobility on the forced swim test in PI-treated rats (89.0±15.5s vs. 156.7±18.5s). Meanwhile, CX546 delivered locally into the NAc provided pain-relieving effects in both PI (50% withdrawal threshold of 6.81±1.91g vs. 0.50±0.03g; control n=6, CX546 n=8) and persistent postoperative pain (spared nerve injury – SNI) models (50% withdrawal threshold of 3.85±1.23g vs. 0.45±0.00g; control n=7, CX546 n=11). Blocking AMPA receptors in the NAc with 3-dihydroxy-6-nitro-7-sulfamoyl-benzo[f]quinoxaline-2, 3-dione (NBQX) inhibited these pain-relieving effects (50% withdrawal threshold of 7.18±1.52g vs. 1.59±0.66g; n=8 for PI groups; 10.70±3.45g vs. 1.39±0.88g; n=4 for SNI groups). Conclusions AMPAkines relieves postoperative pain by activating AMPA receptors in the NAc. PMID:27627816

  13. AMPAkines Target the Nucleus Accumbens to Relieve Postoperative Pain.

    PubMed

    Su, Chen; Lin, Hau Yeuh; Yang, Runtao; Xu, Duo; Lee, Michelle; Pawlak, Natalie; Norcini, Monica; Sideris, Alexandra; Recio-Pinto, Esperanza; Huang, Dong; Wang, Jing

    2016-11-01

    AMPAkines augment the function of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors in the brain to increase excitatory outputs. These drugs are known to relieve persistent pain. However, their role in acute pain is unknown. Furthermore, a specific molecular and anatomic target for these novel analgesics remains elusive. The authors studied the analgesic role of an AMPAkine, CX546, in a rat paw incision (PI) model of acute postoperative pain. The authors measured the effect of AMPAkines on sensory and depressive symptoms of pain using mechanical hypersensitivity and forced swim tests. The authors asked whether AMPA receptors in the nucleus accumbens (NAc), a key node in the brain's reward and pain circuitry, can be a target for AMPAkine analgesia. Systemic administration of CX546 (n = 13), compared with control (n = 13), reduced mechanical hypersensitivity (50% withdrawal threshold of 6.05 ± 1.30 g [mean ± SEM] vs. 0.62 ± 0.13 g), and it reduced depressive features of pain by decreasing immobility on the forced swim test in PI-treated rats (89.0 ± 15.5 vs. 156.7 ± 18.5 s). Meanwhile, CX546 delivered locally into the NAc provided pain-relieving effects in both PI (50% withdrawal threshold of 6.81 ± 1.91 vs. 0.50 ± 0.03 g; control, n = 6; CX546, n = 8) and persistent postoperative pain (spared nerve injury) models (50% withdrawal threshold of 3.85 ± 1.23 vs. 0.45 ± 0.00 g; control, n = 7; CX546, n = 11). Blocking AMPA receptors in the NAc with 2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo[f]quinoxaline-2,3-dione inhibited these pain-relieving effects (50% withdrawal threshold of 7.18 ± 1.52 vs. 1.59 ± 0.66 g; n = 8 for PI groups; 10.70 ± 3.45 vs. 1.39 ± 0.88 g; n = 4 for spared nerve injury groups). AMPAkines relieve postoperative pain by acting through AMPA receptors in the NAc.

  14. Effects of Melatonin on Anti-oxidative Systems and Photosystem II in Cold-Stressed Rice Seedlings

    PubMed Central

    Han, Qiao-Hong; Huang, Bo; Ding, Chun-Bang; Zhang, Zhong-Wei; Chen, Yang-Er; Hu, Chao; Zhou, Li-Jun; Huang, Yan; Liao, Jin-Qiu; Yuan, Shu; Yuan, Ming

    2017-01-01

    Melatonin (N-acetyl-5-methoxytryptamine) plays important role in multiple plant developmental processes and stress responses. We investigated the possible mediatory role of melatonin in growth, photosynthesis, and the response to cold stress in rice by using three different experiments: soaking seed; immersing roots, and spraying to leaves with 0, 20, or 100 μM melatonin. After 6 days of cold stress, the growth of rice seedlings was significantly inhibited, but this inhibition was alleviated by exogenous melatonin. Furthermore, exogenous melatonin pretreatment alleviated the accumulation of reactive oxygen species, malondialdehyde and cell death induced by cold stress. Melatonin pretreatment also relieved the stress-induced inhibitions to photosynthesis and photosystem II activities. Further investigations showed that, antioxidant enzyme activities and non-enzymatic antioxidant levels were increased by melatonin pretreatments. The treatment methods of seed soaking and root immersion were more effective in improving cold stress resistance than the spraying method. The results also indicated the dose-dependent response of melatonin on rice physiological, biochemical, and photosynthetic parameters. PMID:28553310

  15. Vulnerability of US thermoelectric power generation to climate change when incorporating state-level environmental regulations

    NASA Astrophysics Data System (ADS)

    Liu, Lu; Hejazi, Mohamad; Li, Hongyi; Forman, Barton; Zhang, Xiao

    2017-08-01

    Previous modelling studies suggest that thermoelectric power generation is vulnerable to climate change, whereas studies based on historical data suggest the impact will be less severe. Here we explore the vulnerability of thermoelectric power generation in the United States to climate change by coupling an Earth system model with a thermoelectric power generation model, including state-level representation of environmental regulations on thermal effluents. We find that the impact of climate change is lower than in previous modelling estimates due to an inclusion of a spatially disaggregated representation of environmental regulations and provisional variances that temporarily relieve power plants from permit requirements. More specifically, our results indicate that climate change alone may reduce average generating capacity by 2-3% by the 2060s, while reductions of up to 12% are expected if environmental requirements are enforced without waivers for thermal variation. Our work highlights the significance of accounting for legal constructs and underscores the effects of provisional variances in addition to environmental requirements.

  16. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Huang, Pu; Brutnell, Thomas P.

    C 4 photosynthesis is used by only three percent of all flowering plants, but explains a quarter of global primary production, including some of the worlds’ most important cereals and bioenergy grasses. Recent advances in our understanding of C 4 development can be attributed to the application of comparative transcriptomics approaches that has been fueled by high throughput sequencing. Global surveys of gene expression conducted between different developmental stages or on phylogenetically closely related C 3 and C 4 species are providing new insights into C 4 function, development and evolution. Importantly, through co-expression analysis and comparative genomics, these studiesmore » help define novel candidate genes that transcend traditional genetic screens. In this review, we briefly summarize the major findings from recent transcriptomic studies, compare and contrast these studies to summarize emerging consensus, and suggest new approaches to exploit the data. Lastly, we suggest using Setaria viridis as a model system to relieve a major bottleneck in genetic studies of C 4 photosynthesis, and discuss the challenges and new opportunities for future comparative transcriptomic studies.« less

  17. Polysaccharides from Arctium lappa L.: Chemical structure and biological activity.

    PubMed

    Carlotto, Juliane; de Souza, Lauro M; Baggio, Cristiane H; Werner, Maria Fernanda de P; Maria-Ferreira, Daniele; Sassaki, Guilherme L; Iacomini, Marcello; Cipriani, Thales R

    2016-10-01

    The plant Arctium lappa L. is popularly used to relieve symptoms of inflammatory disorders. A crude polysaccharide fraction (SAA) resulting of aqueous extraction of A. lappa leaves showed a dose dependent anti-edematogenic activity on carrageenan-induced paw edema, which persisted for up to 48h. Sequential fractionation by ultrafiltration at 50kDa and 30kDa cut-off membranes yielded three fractions, namely RF50, RF30, and EF30. All these maintained the anti-edematogenic effect, but RF30 showed a more potent action, inhibiting 57% of the paw edema at a dose of 4.9mg/kg. The polysaccharide RF30 contained galacturonic acid, galactose, arabinose, rhamnose, glucose, and mannose in a 7:4:2:1:2:1 ratio and had a Mw of 91,000g/mol. Methylation analysis and NMR spectroscopy indicated that RF30 is mainly constituted by a type I rhamnogalacturonan branched by side chains of types I and II arabinogalactans, and arabinan. Copyright © 2016 Elsevier B.V. All rights reserved.

  18. Trans-nasal-trans-sphenoidal brain injury by a fencing foil: an unusual case report and brief literature review.

    PubMed

    Özay, Rafet; Balkan, Mehmet S; Tönge, Çağhan; Şekerci, Zeki

    2017-11-01

    In this report, the authors present an unusual case of a 10-year-old child who suffered a severe headache and rhinorrhea that occurred as a result of fencing foil sports injury via trans-nasal-trans-sphenoidal (TNTS) pathway. Following trauma, the child had shown neurological symptoms such a pupil dilatation, change in consciousness and mild hemiparesia. Imaging demonstrated destruction of bone structures including posterior wall of sphenoid sinus and antero-superior part of sella turcica, and also a contusion at right thalamic region. For treatment of rhinorrhea lumbar drainage system (LDS) had planted in order to relieve cerebrospinal fluid (CSF) leakage. After the treatment, the patient had fully recovered without any need of further surgical intervention. CSF leakage had prevented and neurological symptoms were completely treated. This case represents the first report of brain injury via TNTS pathway in a sports practice. Diagnosis, clinic follow-up and treatment options of this rare accidental sports injury are discussed.

  19. The role of arginine vasopressin in electroacupuncture treatment of primary sciatica in human.

    PubMed

    Zhao, Xue-Yan; Zhang, Qi-Shun; Yang, Jun; Sun, Fang-Jie; Wang, Da-Xin; Wang, Chang-Hong; He, Wei-Ya

    2015-08-01

    It has been implicated that electroacupuncture can relieve the symptoms of sciatica with the increase of pain threshold in human, and arginine vasopressin (AVP) in the brain rather than the spinal cord and blood circulation participates in antinociception. Our previous study has proven that AVP in the brain played a role in the process of electroacupuncture analgesia in rat. The goal of the present study was to investigate the role of AVP in electroacupuncture in treating primary sciatica in human. The results showed that (1) AVP concentration of cerebrospinal fluid (CSF) (7.5 ± 2.5 pg/ml), not plasma (13.2 ± 4.2 pg/ml) in primary sciatica patients was lower than that in health volunteers (16.1 ± 3.8 pg/ml and 12.3 ± 3.4 pg/ml), although the osmotic pressure in CSF and plasma did not change; (2) electroacupuncture of the bilateral "Zusanli" points (St. 36) for 60 min relieved the pain sensation in primary sciatica patients; (3) electroacupuncture increased the AVP level of CSF, not plasma in primary sciatica patients; and (4) there was the positive correlation between the effect of electroacupuncture relieving the pain and the AVP level of CSF in the primary sciatica patients. The data suggested that central AVP, not peripheral AVP might improve the effect of electroacupuncture treatment of primary sciatica in human, i.e., central AVP might take part in the electroacupuncture relieving the pain sensation in primary sciatica patients. Copyright © 2015 Elsevier B.V. All rights reserved.

  20. Q&A: How do gene regulatory networks control environmental responses in plants?

    PubMed

    Sun, Ying; Dinneny, José R

    2018-04-11

    A gene regulatory network (GRN) describes the hierarchical relationship between transcription factors, associated proteins, and their target genes. Studying GRNs allows us to understand how a plant's genotype and environment are integrated to regulate downstream physiological responses. Current efforts in plants have focused on defining the GRNs that regulate functions such as development and stress response and have been performed primarily in genetically tractable model plant species such as Arabidopsis thaliana. Future studies will likely focus on how GRNs function in non-model plants and change over evolutionary time to allow for adaptation to extreme environments. This broader understanding will inform efforts to engineer GRNs to create tailored crop traits.

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