Sample records for creates additional challenges

  1. Additive Manufacturing and 3D Printing in NASA: An Overview of Current Projects and Future Initiatives for Space Exploration

    NASA Technical Reports Server (NTRS)

    Clinton, R. G., Jr.

    2014-01-01

    NASA, including each Mission Directorate, is investing in, experimenting with, and/or utilizing AM across a broad spectrum of applications and projects; Centers have created and are continuing to create partnerships with industry, other Government Agencies, other Centers, and Universities; In-house additive manufacturing capability enables rapid iteration of the entire design, development and testing process, increasing innovation and reducing risk and cost to projects; For deep space exploration, AM offers significant reduction to logistics costs and risk by providing ability to create on demand; There are challenges: Overwhelming message from recent JANNAF AM for Propulsion Applications TIM was "certification."; NASA will continue to work with our partners to address this and other challenges to advance the state of the art in AM and incorporate these capabilities into an array of applications from aerospace to science missions to deep space exploration.

  2. Design and Implementation of Therapist Online Counseling

    ERIC Educational Resources Information Center

    Thomas, Aaron O.; Lee, Geoff; Ess, Brian

    2015-01-01

    The following paper describes the rationale for creating an online therapy program of cognitive behavioral therapy, or CBT, for students at the University of Florida who are struggling with stress and anxiety. In addition, the paper discusses the unique challenges of the instructional design process of creating psychoeducational materials through…

  3. Challenges and Opportunities for Testing Students Who Are Deaf or Hard of Hearing: Information for Educators on Creating Test Equity. Test Equity Considerations: Schools

    ERIC Educational Resources Information Center

    PEPNet-West, 2010

    2010-01-01

    For most students, test taking is a challenge. For students who are deaf or hard of hearing, classroom quizzes, tests, and exams are even more challenging. Standardized tests--The SAT, ACT, state proficiency tests, No Child Left Behind annual tests, and psychoeducational evaluations--present additional challenges for students who are deaf or hard…

  4. Big Data Goes Personal: Privacy and Social Challenges

    ERIC Educational Resources Information Center

    Bonomi, Luca

    2015-01-01

    The Big Data phenomenon is posing new challenges in our modern society. In addition to requiring information systems to effectively manage high-dimensional and complex data, the privacy and social implications associated with the data collection, data analytics, and service requirements create new important research problems. First, the high…

  5. Linking Serious Game Narratives with Pedagogical Theories and Pedagogical Design Strategies

    ERIC Educational Resources Information Center

    De Troyer, Olga; Van Broeckhoven, Frederik; Vlieghe, Joachim

    2017-01-01

    Narrative-based serious games present pedagogical content and interventions through an interactive narrative. To ensure effective learning in such kind of serious games, designers are not only faced with the challenge of creating a compelling narrative, but also with the additional challenge of incorporating suitable pedagogical strategies.…

  6. Marking and Moderation in the UK: False Assumptions and Wasted Resources

    ERIC Educational Resources Information Center

    Bloxham, Sue

    2009-01-01

    This article challenges a number of assumptions underlying marking of student work in British universities. It argues that, in developing rigorous moderation procedures, we have created a huge burden for markers which adds little to accuracy and reliability but creates additional work for staff, constrains assessment choices and slows down…

  7. Exploring Metaskills of Knowledge-Creating Inquiry in Higher Education

    ERIC Educational Resources Information Center

    Muukkonen, Hanni; Lakkala, Minna

    2009-01-01

    The skills of knowledge-creating inquiry are explored as a challenge for higher education. The knowledge-creation approach to learning provides a theoretical tool for addressing them: In addition to the individual and social aspects in regulation of inquiry, the knowledge-creation approach focuses on aspects related to advancing shared objects of…

  8. Perceptions of ESL Program Management in Canadian Higher Education: A Qualitative Case Study

    ERIC Educational Resources Information Center

    Eaton, Sarah Elaine

    2017-01-01

    ESL programs at post-secondary institutions must often generate revenue in addition to teaching students English. Institutions often impose explicit expectations on these programs to generate profit, creating unique challenges for those who administer them. This qualitative case study investigated challenges faced by ESL program directors at one…

  9. Creating a Space for Student Voice in an Educational Evaluation

    ERIC Educational Resources Information Center

    Bourke, Roseanna; MacDonald, Jo

    2018-01-01

    Evaluation research focusing on educational initiatives that impact on the learning and lives of young people must be challenged to incorporate 'student voice'. In a context of conventional evaluation models of government-led initiatives, student voice is a compelling addition, and challenges the nature of traditional forms of evaluation. It…

  10. Teaching Project Management On-Line: Lessons Learned from MOOCs

    ERIC Educational Resources Information Center

    Falcao, Rita; Fernandes, Luis

    2016-01-01

    Creating a course for teaching project management online in a full online distance-learning environment was a challenge. Working with adult learners from different continents that want to complete a Master degree was an additional challenge. This paper describes how different MOOCs were used to learn about teaching -(meta) e-learning. MOOCs…

  11. Removing a Nail from the Boot Camp Coffin: An Outcome Evaluation of Minnesota's Challenge Incarceration Program

    ERIC Educational Resources Information Center

    Duwe, Grant; Kerschner, Deborah

    2008-01-01

    Using a retrospective, quasiexperimental design, this study evaluates Minnesota's Challenge Incarceration Program (CIP), examining whether it has lowered recidivism and saved money. In addition to utilizing a lengthy follow-up period and multiple measures of recidivism and participation, a multistage sampling design was employed to create a…

  12. It's Not Just "What" You Say: Verbal and Nonverbal Skills Help Leaders Address Challenges and Achieve Outcomes

    ERIC Educational Resources Information Center

    Zoller, Kendall; Lahera, Antonia Issa; Normore, Anthony H.

    2015-01-01

    This article presents a story about two school leaders in a large Southern California urban district who used skills developed in a university school leadership program to create rapport, empathy, and trust while leading through challenging situations and achieving actionable outcomes. In addition to developing relationships in support of…

  13. Diploma R.N.'s: A New Challenge for Career Planning and Placement

    ERIC Educational Resources Information Center

    Bostaph, Charles; Moore, Marti

    1978-01-01

    Need for additional college education or career change is becoming common for registered nurses who are graduates of hospital diploma programs. This creates challenges for career planning and placement professionals, including counseling of R.N.s with a variety of majors and needs who wish to enter fields other than hospital nursing. (Author)

  14. A Knowledge Management Case Study: The First U.S. Navy Expeditionary Strike Group (ESG-3) to Implement Knowledge Management

    DTIC Science & Technology

    2008-01-01

    history. 3D Probably the largest challenge from a logistical point of view was arranging for food, tents, and transportation for the over 15,000...the challenge with excellent results. If there was no standard, the staff created (e.g., pass or fail). Additionally, if the staff felt it could have...backcover. 15 Irma Becerra-Fernandez, Knowledge Management: Challenges , Solutions, and Technologies, (Princeton Hall, 2004),2. 16 http

  15. Improving the accuracy of camber predictions for precast pretensioned concrete beams.

    DOT National Transportation Integrated Search

    2015-07-01

    The discrepancies between the designed and measured camber of precast pretensioned concrete beams (PPCBs) observed by the : Iowa DOT have created challenges in the field during bridge construction, causing construction delays and additional costs. Th...

  16. Student Design Printed on ISS 3-D Printer

    NASA Image and Video Library

    2016-06-15

    The winning entry in the Future Engineers Space Tool Challenge is printed in the Additive Manufacturing Facility on the International Space station. This time-lapse video shows the creation of the Multipurpose Precision Maintenance Tool created by University of Alabama in Huntsville student Robert Hillan.

  17. Risk management consideration in the bioeconomy

    Treesearch

    Camilla Abbati de Assis; Ronalds Gonzalez; Stephen Kelley; Hasan Jameel; Ted Bilek; Jesse Daystar; Robert Handfield; Jay Golden; Jeff Prestemon; Damien Singh

    2017-01-01

    In investing in a new venture, companies aim to increase their competitiveness and generate value in scenarios where volatile markets, geopolitical instabilities, and disruptive technologies create uncertainty and risk. The biobased industry poses additional challenges as it competes in a mature, highly efficient market, dominated by...

  18. Could Wind or Solar Energy Replace Diesel Generators for Aviation Ground Maintenance Operations?

    DTIC Science & Technology

    2013-04-17

    power. Both of these systems depend on the sun to produce energy. Wind turbines depend on wind which results from the uneven heating of the earth...inefficient. In addition to these limitations, both systems are costly and their installation brings a number of challenges. For the wind turbines ...these challenges include: the obstruction created by the height of the turbines near airfields, the amount of land necessary for a 7 turbines wind farm

  19. Strategies and Resources for Enhancing the Achievement of Mobile Students

    ERIC Educational Resources Information Center

    Titus, Dale N.

    2007-01-01

    Because studies reveal a relationship between high student mobility and low academic achievement, school administrators are faced with the challenge of raising academic achievement in an era of increased student mobility. Wide variations in state requirements create additional difficulties for mobile students, who tend to be disadvantaged in other…

  20. Creating Communities of Professional Practice in the Correctional Education Classroom

    ERIC Educational Resources Information Center

    DelliCarpini, Margo

    2008-01-01

    Meaningful professional development (PD) for correctional educators is not frequently addressed, though they work with students who are most at-risk in terms of academic success. In addition to the challenges that the students themselves face, there are obstacles inherent in administering educational programs in correctional facilities whose goals…

  1. Increasing Student Success and Retention: A Multidimensional Approach

    ERIC Educational Resources Information Center

    Fowler, Paul R.; Boylan, Hunter R.

    2010-01-01

    Students who are seriously academically deficient, those who are underprepared in all subjects, face many academic challenges as they begin their coursework in higher education. However, students also face nonacademic and personal issues that create additional barriers to success. The results of this study suggest that increases in student success…

  2. Suicide and Its Impact on Campus

    ERIC Educational Resources Information Center

    Levine, Heidi

    2008-01-01

    Although any death on campus can have profound effects on the community, leaving survivors to grope for meaning and cope with feelings of grief and loss, deaths by suicide entail several additional challenges. Shneidman (2001) estimated that an individual's suicide touches the lives of at least six others, creating wide-ranging psychological…

  3. Fluid-Structure Interaction Modeling of the Reefed Stages of the Orion Spacecraft Main Parachutes

    NASA Astrophysics Data System (ADS)

    Boswell, Cody W.

    Spacecraft parachutes are typically used in multiple stages, starting with a "reefed" stage where a cable along the parachute skirt constrains the diameter to be less than the diameter in the subsequent stage. After a certain period of time during the descent, the cable is cut and the parachute "disreefs" (i.e. expands) to the next stage. Computing the parachute shape at the reefed stage and fluid-structure interaction (FSI) modeling during the disreefing involve computational challenges beyond those we have in FSI modeling of fully-open spacecraft parachutes. These additional challenges are created by the increased geometric complexities and by the rapid changes in the parachute geometry. The computational challenges are further increased because of the added geometric porosity of the latest design, where the "windows" created by the removal of panels and the wider gaps created by the removal of sails compound the geometric and flow complexity. Orion spacecraft main parachutes will have three stages, with computation of the Stage 1 shape and FSI modeling of disreefing from Stage 1 to Stage 2 being the most challenging. We present the special modeling techniques we devised to address the computational challenges and the results from the computations carried out. We also present the methods we devised to calculate for a parachute gore the radius of curvature in the circumferential direction. The curvature values are intended for quick and simple engineering analysis in estimating the structural stresses.

  4. Visualising the invisible

    NASA Astrophysics Data System (ADS)

    Laychak, M. B.

    2008-06-01

    In addition to the optical camera Megacam, the Canada-France-Hawaii Telescope operates a large field infrared camera, Wircam, and a spectrograph/spectropolimeter, Espadons. When these instruments were commissioned, the challenge arose to create educational outreach programmes incorporating the concepts of infrared astronomy and spectroscopy. We integrated spectroscopy into discussions of extrasolar planets and the search for life, two topics routinely requested by teachers for classroom talks. Making the infrared accessible to students provided a unique challenge, one that we met through the implementation and use of webcams modified for infrared use.

  5. How to Create a 3D Model from Scanned Data in 5 Easy Steps

    NASA Technical Reports Server (NTRS)

    Hagen, Richard

    2017-01-01

    Additive manufacturing is a cost effective way to generate copies of damaged parts for demonstrations. Integrating scanned data of a damaged area into an existing model may be challenging. However, using the relatively inexpensive Nettfab software (from one can generate a "watertight" model that is easy to print.

  6. How Close Is Close Reading?

    ERIC Educational Resources Information Center

    Saccomano, Doreen

    2014-01-01

    Close Reading is a strategy that can be used when reading challenging text. This strategy requires teachers to provide scaffolding, and create opportunities for think-alouds and rereading of text in order to help students become active readers who focus on finding text-based support for their answers. In addition, teachers must also be aware of…

  7. Professional Development for Biology Teachers in the Knowledge Economy

    ERIC Educational Resources Information Center

    Eiser, Simone; Knight, Bruce Allen

    2008-01-01

    Increasingly, the general media cover new advancements and research in the field of biology. Stem cell research, emerging diseases and bioethics are some of the issues gaining public attention. The rate of increase of these new developments creates additional challenges to teachers of biology as they try to remain abreast of new information and…

  8. Uncovering University Students' Readiness through Their Assessment of Workplace Communication Skills

    ERIC Educational Resources Information Center

    Magogwe, Joel M.; Nkosana, Leonard B. M.; Ntereke, Beauty B.

    2014-01-01

    Employers in today's competitive and challenging global world prefer employees who possess "soft skills" in addition to "hard skills" because they make an impact and create a good impression in the workplace. This study examined employment readiness of the University of Botswana (UB) students who took the Advanced Communication…

  9. Examining Oregon Agriculture Teachers' Professional Development Needs by Career Phase

    ERIC Educational Resources Information Center

    Sorensen, Tyson J.; Lambert, Misty D.; McKim, Aaron J.

    2014-01-01

    Agriculture teachers face challenges at every stage of their career, creating a need for professional development to meet their individual needs. Additionally, research suggests the need for periodic needs assessments to be conducted within individual states. The purpose of this study was to identify and describe, using the Borich needs assessment…

  10. Structural technology challenges for evolutionary growth of Space Station Freedom

    NASA Technical Reports Server (NTRS)

    Doiron, Harold H.

    1990-01-01

    A proposed evolutionary growth scenario for Space Station Freedom was defined recently by a NASA task force created to study requirements for a Human Exploration Initiative. The study was an initial response to President Bush's July 20, 1989 proposal to begin a long range program of human exploration of space including a permanently manned lunar base and a manned mission to Mars. This growth scenario evolves Freedom into a critical transportation node to support lunar and Mars missions. The growth scenario begins with the Assembly Complete configuration and adds structure, power, and facilities to support a Lunar Transfer Vehicle (LTV) verification flight. Evolutionary growth continues to support expendable, then reusable LTV operations, and finally, LTV and Mars Transfer Vehicle (MTV) operations. The significant structural growth and additional operations creating new loading conditions will present new technological and structural design challenges in addition to the considerable technology requirements of the baseline Space Station Freedom program. Several structural design and technology issues of the baseline program are reviewed and related technology development required by the growth scenario is identified.

  11. Challenges for Electronics in the Vision for Space Exploration

    NASA Technical Reports Server (NTRS)

    LaBel, Kenneth A.

    2005-01-01

    This presentation has been a brief snapshot discussing electronics and Exploration-related challenges. The vision for Space Exploration creates a new paradigm for NASA missions. This includes transport (Crew Exploration Vehicle-CEV), and lunar and Mars Exploration and human presence. If one considers the additional hazards faced by these concepts versus more traditional NASA missions, multiple challenges surface for reliable utilization of electronic parts. The true challenge is to provide a risk as low as reasonably achievable (ALARA-a traditional biological radiation exposure term), while still providing cost effective solutions. This presentation also discusses the hazard for electronic parts and exploration, the types of electronic parts for exploration, and the critical juncture for space usage of commercial changes in the electronics world.

  12. 2015 Summer Design Challenge: Team A&E (2241) Additively Manufactured Discriminator.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Miller, Sarah E.; Moore, Brandon James

    Current discriminator designs are based on historical designs and traditional manufacturing methods. The goal of this project was to form non-traditional groups to create novel discriminator designs by taking advantage of additive manufacturing. These designs would expand current discriminator designs and provide insight on the applicability of additive manufacturing for future projects. Our design stretched the current abilities of additive manufacturing and noted desired improvements for the future. Through collaboration with NSC, we noted several additional technologies which work well with additive manufacturing such as topology optimization and CT scanning and determined how these technologies could be improved to bettermore » combine with additive manufacturing.« less

  13. The structure of a thermophilic kinase shapes fitness upon random circular permutation

    PubMed Central

    Jones, Alicia M.; Mehta, Manan M.; Thomas, Emily E.; Atkinson, Joshua T.; Segall-Shapiro, Thomas H.; Liu, Shirley; Silberg, Jonathan J.

    2016-01-01

    Proteins can be engineered for synthetic biology through circular permutation, a sequence rearrangement where native protein termini become linked and new termini are created elsewhere through backbone fission. However, it remains challenging to anticipate a protein’s functional tolerance to circular permutation. Here, we describe new transposons for creating libraries of randomly circularly permuted proteins that minimize peptide additions at their termini, and we use transposase mutagenesis to study the tolerance of a thermophilic adenylate kinase (AK) to circular permutation. We find that libraries expressing permuted AK with either short or long peptides amended to their N-terminus yield distinct sets of active variants and present evidence that this trend arises because permuted protein expression varies across libraries. Mapping all sites that tolerate backbone cleavage onto AK structure reveals that the largest contiguous regions of sequence that lack cleavage sites are proximal to the phosphotransfer site. A comparison of our results with a range of structure-derived parameters further showed that retention of function correlates to the strongest extent with the distance to the phosphotransfer site, amino acid variability in an AK family sequence alignment, and residue-level deviations in superimposed AK structures. Our work illustrates how permuted protein libraries can be created with minimal peptide additions using transposase mutagenesis, and they reveal a challenge of maintaining consistent expression across permuted variants in a library that minimizes peptide additions. Furthermore, these findings provide a basis for interpreting responses of thermophilic phosphotransferases to circular permutation by calibrating how different structure-derived parameters relate to retention of function in a cellular selection. PMID:26976658

  14. The Structure of a Thermophilic Kinase Shapes Fitness upon Random Circular Permutation.

    PubMed

    Jones, Alicia M; Mehta, Manan M; Thomas, Emily E; Atkinson, Joshua T; Segall-Shapiro, Thomas H; Liu, Shirley; Silberg, Jonathan J

    2016-05-20

    Proteins can be engineered for synthetic biology through circular permutation, a sequence rearrangement in which native protein termini become linked and new termini are created elsewhere through backbone fission. However, it remains challenging to anticipate a protein's functional tolerance to circular permutation. Here, we describe new transposons for creating libraries of randomly circularly permuted proteins that minimize peptide additions at their termini, and we use transposase mutagenesis to study the tolerance of a thermophilic adenylate kinase (AK) to circular permutation. We find that libraries expressing permuted AKs with either short or long peptides amended to their N-terminus yield distinct sets of active variants and present evidence that this trend arises because permuted protein expression varies across libraries. Mapping all sites that tolerate backbone cleavage onto AK structure reveals that the largest contiguous regions of sequence that lack cleavage sites are proximal to the phosphotransfer site. A comparison of our results with a range of structure-derived parameters further showed that retention of function correlates to the strongest extent with the distance to the phosphotransfer site, amino acid variability in an AK family sequence alignment, and residue-level deviations in superimposed AK structures. Our work illustrates how permuted protein libraries can be created with minimal peptide additions using transposase mutagenesis, and it reveals a challenge of maintaining consistent expression across permuted variants in a library that minimizes peptide additions. Furthermore, these findings provide a basis for interpreting responses of thermophilic phosphotransferases to circular permutation by calibrating how different structure-derived parameters relate to retention of function in a cellular selection.

  15. The urbanization of wildlife management:Social science, conflict, and decision making

    Treesearch

    Michael E. Patterson; Jessica M. Montag; Daniel R. Williams

    2003-01-01

    Increasing urbanization of rural landscapes has created new challenges for wildlife management. In addition to changes in the physical landscape, urbanization has also produced changes in the socio-cultural landscape. The greater distancing from direct interaction with wildlife in urbanized societies has led to the emergence of a culture whose meanings for wildlife are...

  16. The Role of School Technicians in Promoting Science through Practical Work

    ERIC Educational Resources Information Center

    Helliar, Anne T.; Harrison, Timothy G.

    2011-01-01

    This is a review of the role of practical work in UK's secondary school science lessons, the impact that practical work has in the promotion of science, the challenges created through use of non-specialist science teachers and a possible additional role for science technicians. The paper considers how improved deployment of suitably experienced…

  17. Prediction of Postpartum Social Support and Symptoms of Depression in Pregnant Adolescents: A Pilot Study

    ERIC Educational Resources Information Center

    Logsdon, M. Cynthia; Cross, Rene; Williams, Beverly; Simpson, Theresa

    2004-01-01

    Many pregnant adolescents remain in school, creating unique challenges for professionals to meet their educational and health needs. In this descriptive pilot study of pregnant adolescents (n = 26), 68% demonstrated symptoms of depression as measured by the Center for Epidemiologic Studies Depression Scale (CES-D). In addition, there was an…

  18. A study of a museum-school partnership

    NASA Astrophysics Data System (ADS)

    Wojton, Mary Ann

    Partnerships between museums and schools never have been more important than they are today. Schools, especially urban schools, are facing challenges, including low student achievement and difficulty obtaining funding. Partners can help schools overcome these challenges by sharing educational and financial resources. Nearly 11,000 American museums spend more than $1 billion annually to provide over 18 million instructional hours for k-12 educational programs such as professional development for teachers, guided field trips, and staff visits to schools. Museums would seem like natural partners for challenged urban schools. Yet museums and schools struggle to establish and maintain effective partnerships. This study examined a partnership between a science center and an urban elementary school to provide additional knowledge and resources for those in the field to overcome these challenges in order to create relationships that help students. Using qualitative methods with interpretive descriptive purposes (Erickson, 1986; Glesne, 1999; Lincoln & Guba, 2000), the research design is based on several methods of data collection, including face-to-face, semi-structured interviews; observations; written text; and field notes. Participants in this study included students, parents, teachers, school administrators and museum educators. In addition, adult representatives of community organizations were interviewed to determine the impact of the partnership on the community. The study found that an effective partnership will have four basic elements: mutual goals, communication plan, key leader support, planning and research, and four interpersonal elements: personal responsibility, honesty, communication at the intimate level, and trust. Partners may have difficulty developing these to their fullest extent due to time limitations. No partnership is perfect. By creating strong interpersonal relationships, partners can mitigate challenges caused by limited basic elements and increase the likelihood that their partnership will be effective.

  19. Developing targets for radiation transport experiments at the Omega laser facility

    DOE PAGES

    Capelli, Deanna; Charsley-Groffman, C. A.; Randolph, Randall Blaine; ...

    2017-07-13

    Targets have been developed to measure supersonic radiation transport in aerogel foams using absorption spectroscopy. The target consists of an aerogel foam uniformly doped with either titanium or scandium inserted into an undoped aerogel foam package. This creates a localized doped foam region to provide spatial resolution for the measurement. Development and characterization of the foams is a key challenge in addition to machining and assembling the two foams so they mate without gaps. The foam package is inserted into a beryllium sleeve and mounted on a gold hohlraum. The target is mounted to a holder created using additive manufacturingmore » and mounted on a stalk. As a result, the manufacturing of the components, along with assembly and metrology of the target are described here.« less

  20. Developing targets for radiation transport experiments at the Omega laser facility

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Capelli, Deanna; Charsley-Groffman, C. A.; Randolph, Randall Blaine

    Targets have been developed to measure supersonic radiation transport in aerogel foams using absorption spectroscopy. The target consists of an aerogel foam uniformly doped with either titanium or scandium inserted into an undoped aerogel foam package. This creates a localized doped foam region to provide spatial resolution for the measurement. Development and characterization of the foams is a key challenge in addition to machining and assembling the two foams so they mate without gaps. The foam package is inserted into a beryllium sleeve and mounted on a gold hohlraum. The target is mounted to a holder created using additive manufacturingmore » and mounted on a stalk. As a result, the manufacturing of the components, along with assembly and metrology of the target are described here.« less

  1. Creating environments that foster academic integrity.

    PubMed

    Tippitt, Michelle Pixley; Ard, Nell; Kline, Juanita Reese; Tilghman, Joan; Chamberlain, Barbara; Meagher, P Gail

    2009-01-01

    A number of studies related to academic dishonesty within the nursing student population have been published; however, little has been written in the nursing literature regarding academic integrity and means of promoting this value. In addition to the many short-term solutions to prevent cheating and dissuade academic misconduct that are offered, solutions that promote long-term affective changes underlying the acquisition of academic integrity are needed. This article provides a context for discussions related to academic integrity, explores issues facing faculty when dealing with this challenge, and offers short-term and long-term strategies for creating environments that foster academic integrity.

  2. Genome assembly reborn: recent computational challenges

    PubMed Central

    2009-01-01

    Research into genome assembly algorithms has experienced a resurgence due to new challenges created by the development of next generation sequencing technologies. Several genome assemblers have been published in recent years specifically targeted at the new sequence data; however, the ever-changing technological landscape leads to the need for continued research. In addition, the low cost of next generation sequencing data has led to an increased use of sequencing in new settings. For example, the new field of metagenomics relies on large-scale sequencing of entire microbial communities instead of isolate genomes, leading to new computational challenges. In this article, we outline the major algorithmic approaches for genome assembly and describe recent developments in this domain. PMID:19482960

  3. The Enterprise 2.0 Concept: Challenges on Data and Information Security

    NASA Astrophysics Data System (ADS)

    Silva, Ana; Moreira, Fernando; Varajão, João

    The Web 2.0 wave has "hit" businesses all over the world, with companies taking advantage of the 2.0 concept and new applications stimulating collaboration between employees, and also with external partners (suppliers, contractors, universities, R&D organizations and others). However, the use of Web 2.0 applications inside organizations has created additional security challenges, especially regarding data and information security. Companies need to be aware of these risks when deploying the 2.0 concept and take a proactive approach on security. In this paper are identified and discussed some of the challenges and risks of the use of Web 2.0 tools, namely when it comes to securing companies' intellectual property.

  4. Development and Deployment of the Extended Reach Sluicing System (ERSS) for Retrieval of Hanford Single Shell Tank Waste. Draft

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bauer, Roger E.; Figley, Reed R.; Innes, A. G.

    2013-11-11

    A history of the evolution and the design development of Extended Reach Sluicer System (ERSS) is presented. Several challenges are described that had to be overcome to create a machine that went beyond the capabilities of prior generation sluicers to mobilize waste in Single Shell Tanks for pumping into Double Shell Tank receiver tanks. Off-the-shelf technology and traditional hydraulic fluid power systems were combined with the custom-engineered components to create the additional functionality of the ERSS, while still enabling it to fit within very tight entry envelope into the SST. Problems and challenges inevitably were encountered and overcome in waysmore » that enhance the state of the art of fluid power applications in such constrained environments. Future enhancements to the ERSS design are explored for retrieval of tanks with different dimensions and internal obstacles.« less

  5. Chronic pain in hypermobility syndrome and Ehlers–Danlos syndrome (hypermobility type): it is a challenge

    PubMed Central

    Scheper, Mark C; de Vries, Janneke E; Verbunt, Jeanine; Engelbert, Raoul HH

    2015-01-01

    Generalized joint hypermobility (GJH) is highly prevalent among patients diagnosed with chronic pain. When GJH is accompanied by pain in ≥4 joints over a period ≥3 months in the absence of other conditions that cause chronic pain, the hypermobility syndrome (HMS) may be diagnosed. In addition, GJH is also a clinical sign that is frequently present in hereditary diseases of the connective tissue, such as the Marfan syndrome, osteogenesis imperfecta, and the Ehlers–Danlos syndrome. However, within the Ehlers–Danlos spectrum, a similar subcategory of patients having similar clinical features as HMS but lacking a specific genetic profile was identified: Ehlers–Danlos syndrome hypermobility type (EDS-HT). Researchers and clinicians have struggled for decades with the highly diverse clinical presentation within the HMS and EDS-HT phenotypes (Challenge 1) and the lack of understanding of the pathological mechanisms that underlie the development of pain and its persistence (Challenge 2). In addition, within the HMS/EDS-HT phenotype, there is a high prevalence of psychosocial factors, which again presents a difficult issue that needs to be addressed (Challenge 3). Despite recent scientific advances, many obstacles for clinical care and research still remain. To gain further insight into the phenotype of HMS/EDS-HT and its mechanisms, clearer descriptions of these populations should be made available. Future research and clinical care should revise and create consensus on the diagnostic criteria for HMS/EDS-HT (Solution 1), account for clinical heterogeneity by the classification of subtypes within the HMS/EDS-HT spectrum (Solution 2), and create a clinical core set (Solution 3). PMID:26316810

  6. Chronic pain in hypermobility syndrome and Ehlers-Danlos syndrome (hypermobility type): it is a challenge.

    PubMed

    Scheper, Mark C; de Vries, Janneke E; Verbunt, Jeanine; Engelbert, Raoul Hh

    2015-01-01

    Generalized joint hypermobility (GJH) is highly prevalent among patients diagnosed with chronic pain. When GJH is accompanied by pain in ≥4 joints over a period ≥3 months in the absence of other conditions that cause chronic pain, the hypermobility syndrome (HMS) may be diagnosed. In addition, GJH is also a clinical sign that is frequently present in hereditary diseases of the connective tissue, such as the Marfan syndrome, osteogenesis imperfecta, and the Ehlers-Danlos syndrome. However, within the Ehlers-Danlos spectrum, a similar subcategory of patients having similar clinical features as HMS but lacking a specific genetic profile was identified: Ehlers-Danlos syndrome hypermobility type (EDS-HT). Researchers and clinicians have struggled for decades with the highly diverse clinical presentation within the HMS and EDS-HT phenotypes (Challenge 1) and the lack of understanding of the pathological mechanisms that underlie the development of pain and its persistence (Challenge 2). In addition, within the HMS/EDS-HT phenotype, there is a high prevalence of psychosocial factors, which again presents a difficult issue that needs to be addressed (Challenge 3). Despite recent scientific advances, many obstacles for clinical care and research still remain. To gain further insight into the phenotype of HMS/EDS-HT and its mechanisms, clearer descriptions of these populations should be made available. Future research and clinical care should revise and create consensus on the diagnostic criteria for HMS/EDS-HT (Solution 1), account for clinical heterogeneity by the classification of subtypes within the HMS/EDS-HT spectrum (Solution 2), and create a clinical core set (Solution 3).

  7. Herding Cats: Geocuration Practices Employed for Field Research Data Collection Activities and Visualization by Blueprint Earth

    NASA Astrophysics Data System (ADS)

    Hoover, R.; Harrison, M.; Sonnenthal, N.; Hernandez, A.; Pelaez, J.

    2015-12-01

    Researchers investigating interdisciplinary topics must work to understand the barriers created by information siloes in order to productively collaborate on complex Earth science questions. These barriers create acute challenges when research is driven by observations rather than hypotheses, as communication between collaborators hinges on data synthesis techniques that often vary greatly between disciplines. Field data collection across disciplines creates even more challenges, and employing student researchers of varying abilities demands an approach that is structured, and yet still flexible enough to accommodate inherent differences in the subjective portions of student data collection. Blueprint Earth is performing system-level environmental observations in the broad areas of geology, biology, hydrology, and atmospheric science. Traditional field data collection methodologies are employed for ease of reproducibility, but must translate across disciplinary information siloes. Information collected must be readily useable in the formulation of hypotheses based on field observations, which necessitates an understanding of key metrics by all investigators involved in data analysis. Blueprint Earth demonstrates the ability to create clear data standards across several disciplines while incorporating a quality control process and this allows for conversion of data into functional visualizations. Additionally, geocuration is organized such that data will be ready for public dissemination upon completion of field research.

  8. Factors Influencing the Uptake of a Mechatronics Curriculum Initiative in Five Australian Secondary Schools

    ERIC Educational Resources Information Center

    Nicholas, Howard; Ng, Wan

    2012-01-01

    While the ready-made Lego[TM] Robotics kits are popular in schools and are used by students at both primary and secondary year levels, using the Picaxe microcontroller (chip) to create simple electronic devices, including robotic devices is less popular. The latter imposes an additional challenge as a result of the need to construct the universal…

  9. An Exploratory Study of Aggression in School-Age Children: Underlying Factors and Implications for Treatment

    ERIC Educational Resources Information Center

    Priddis, Lynn E.; Landy, Sarah; Moroney, Darren; Kane, Robert

    2014-01-01

    Aggressive behaviour in school-aged children presents a significant challenge for society. If not managed, it can result in adverse academic, social, emotional, and behavioural outcomes for the child. In addition, it can create stress for families and become a significant burden for the community as these children reach adolescence and adulthood,…

  10. Recommendations for Laboratory Containment and Management of Gene Drive Systems in Arthropods.

    PubMed

    Benedict, Mark Q; Burt, Austin; Capurro, Margareth L; De Barro, Paul; Handler, Alfred M; Hayes, Keith R; Marshall, John M; Tabachnick, Walter J; Adelman, Zach N

    2018-01-01

    Versatile molecular tools for creating driving transgenes and other invasive genetic factors present regulatory, ethical, and environmental challenges that should be addressed to ensure their safe use. In this article, we discuss driving transgenes and invasive genetic factors that can potentially spread after their introduction into a small proportion of individuals in a population. The potential of invasive genetic factors to increase their number in natural populations presents challenges that require additional safety measures not provided by previous recommendations regarding accidental release of arthropods. In addition to providing physical containment, invasive genetic factors require greater attention to strain management, including their distribution and identity confirmation. In this study, we focus on insects containing such factors with recommendations for investigators who are creating them, institutional biosafety committees charged with ensuring safety, funding agencies providing support, those managing insectaries handling these materials who are responsible for containment, and other persons who will be receiving insects-transgenic or not-from these facilities. We give specific examples of efforts to modify mosquitoes for mosquito-borne disease control, but similar considerations are relevant to other arthropods that are important to human health, the environment, and agriculture.

  11. Recommendations for Laboratory Containment and Management of Gene Drive Systems in Arthropods

    PubMed Central

    Burt, Austin; Capurro, Margareth L.; De Barro, Paul; Handler, Alfred M.; Hayes, Keith R.; Marshall, John M.; Tabachnick, Walter J.; Adelman, Zach N.

    2018-01-01

    Abstract Versatile molecular tools for creating driving transgenes and other invasive genetic factors present regulatory, ethical, and environmental challenges that should be addressed to ensure their safe use. In this article, we discuss driving transgenes and invasive genetic factors that can potentially spread after their introduction into a small proportion of individuals in a population. The potential of invasive genetic factors to increase their number in natural populations presents challenges that require additional safety measures not provided by previous recommendations regarding accidental release of arthropods. In addition to providing physical containment, invasive genetic factors require greater attention to strain management, including their distribution and identity confirmation. In this study, we focus on insects containing such factors with recommendations for investigators who are creating them, institutional biosafety committees charged with ensuring safety, funding agencies providing support, those managing insectaries handling these materials who are responsible for containment, and other persons who will be receiving insects—transgenic or not—from these facilities. We give specific examples of efforts to modify mosquitoes for mosquito-borne disease control, but similar considerations are relevant to other arthropods that are important to human health, the environment, and agriculture. PMID:29040058

  12. Reframing the narrative of the battered women's movement.

    PubMed

    Arnold, Gretchen; Ake, Jami

    2013-05-01

    Many claim that the battered women's movement has been co-opted and depoliticized. We argue that this narrative of decline should be reframed as one of continual growth that has incorporated evolving feminist frameworks. We show how the movement's first generation of activists has learned from its mistakes and continues to challenge systems that fail survivors of abuse. In addition, a second generation of activists, many of whom are minority women, has created new organizations and new ways to practice intersectionality. We conclude that each strand within the movement brings complementary strengths that can prepare it to meet future challenges.

  13. A reflective teaching challenge to motivate educational innovation.

    PubMed

    Edwards, Roger A; Kirwin, Jennifer; Gonyeau, Michael; Matthews, S James; Lancaster, Jason; DiVall, Margarita

    2014-06-17

    To describe a teaching challenge intended to increase faculty use of evidence-based and student-centered instructional strategies in the demanding school of pharmacy context with technology-savvy students. A teaching challenge was created that required faculty members to incorporate a "new-to-you" innovative teaching method in a class, course, or experiential activity. The method was linked to at least 1 of 7 evidence-based principles for effective teaching. Faculty members were exposed to colleagues' teaching strategies via brief voluntary presentations at department meetings. A post-challenge survey provided assessment data about the challenge. Responses to a baseline survey provided additional information about what faculty members were already doing (52% response rate). Eighty-one percent of faculty respondents completed the challenge. A wide array of new strategies (13 categories such as flipped classrooms and social media) was implemented and 75% included the use of technology. Nearly all respondents (96%) thought that participation in the challenge was worth the effort and planned to participate again the following year. All faculty members intended to continue using their new strategy and 56% planned additional modifications with future implementations. The challenge demonstrated how multiple goals of curricular improvement, faculty development, and student-centered instruction could be achieved together. The teaching challenge motivated most of the faculty members to try something new to them. Links between evidence-based principles and day-to-day activities were strengthened. The new-to-you design placed the challenge within reach of faculty members regardless of their background, subject, or experience.

  14. Academic-correctional health partnerships: preparing the correctional health workforce for the changing landscape-focus group research results.

    PubMed

    Hale, Janet Fraser; Haley, Heather-Lyn; Jones, Judy L; Brennan, Allyson; Brewer, Arthur

    2015-01-01

    Providing health care in corrections is challenging. Attracting clinicians can be equally challenging. The future holds a shortage of nurses and primary care physicians. We have a unique opportunity, now, to develop and stabilize our workforce, create a positive image, and enhance quality before the health care landscape changes even more dramatically. Focus groups were conducted with 22 correctional health care professionals divided into three groups: physicians (6), nurses (4), and nurse practitioners/physician assistants (12). Content focused on curricular themes, but additional themes emerged related to recruitment and retention. This article describes recruitment challenges, strategic themes identified, and the proposed initiatives to support a stable, high-quality correctional health workforce. © The Author(s) 2014.

  15. Research and Resilience: Creating a Research Agenda for Supporting Military Families with Young Children

    ERIC Educational Resources Information Center

    Williams, Dorinda Silver; Mulrooney, Kathleen

    2012-01-01

    The decade of war since the attacks of 9-11 have meant lengthy and repeated combat deployment for millions of service members, many of whom are parents of very young children. In addition to the many challenges inherent to the deployment cycle, issues such as injury, combat stress, and the death of a service member parent are important realities…

  16. Additive Manufacturing Modeling and Simulation A Literature Review for Electron Beam Free Form Fabrication

    NASA Technical Reports Server (NTRS)

    Seufzer, William J.

    2014-01-01

    Additive manufacturing is coming into industrial use and has several desirable attributes. Control of the deposition remains a complex challenge, and so this literature review was initiated to capture current modeling efforts in the field of additive manufacturing. This paper summarizes about 10 years of modeling and simulation related to both welding and additive manufacturing. The goals were to learn who is doing what in modeling and simulation, to summarize various approaches taken to create models, and to identify research gaps. Later sections in the report summarize implications for closed-loop-control of the process, implications for local research efforts, and implications for local modeling efforts.

  17. Meeting ACGME Standards Under a Unified Accreditation System: Challenges for Osteopathic Graduate Medical Education Programs.

    PubMed

    Cummings, Mark

    2017-07-01

    In 2014, the American Osteopathic Association (AOA) and the American Association of Colleges of Osteopathic Medicine signed a memorandum of understanding (MOU) with the Accreditation Council for Graduate Medical Education (ACGME) to create a unified accreditation system for graduate medical education (GME) under the ACGME. The AOA will cease to accredit GME programs on June 30, 2020. By then, AOA-accredited programs need to apply for and achieve ACGME initial accreditation. The terms of the MOU also made it advantageous for some formerly nonteaching hospitals to establish AOA programs, chiefly in primary care, as a step toward future ACGME accreditation.In transitioning AOA programs to the ACGME system, hospitals with osteopathic GME can expect to encounter challenges related to major differences between AOA and ACGME standards. The minimum numbers of residents for ACGME programs in most specialties are greater than those for AOA programs, which will require hospitals that may already be at their federal caps to add additional residency positions. ACGME standards are also more faculty- and staff-intensive and require additional infrastructure, necessitating additional financial investments. In addition, greater curricular specificity in ACGME standards will generate new educational and financial challenges.To address these challenges, hospitals may need to reallocate resources and positions among their current AOA programs, reducing the number of programs (and specialties) they sponsor. It is expected that a number of established and new AOA programs will choose not to pursue ACGME accreditation or will fail to qualify for ACGME initial accreditation.

  18. SOCIAL SECURITY DISABILITY; Additional Outreach and Collaboration on Sharing Medical Records Would Improve Wounded Warriors’ Access to Benefits

    DTIC Science & Technology

    2009-09-01

    told us that staff turnover at DOD facilities creates a challenge. For example, officials from the Colorado Springs SSA office told us that...Missouri West Virginia Colorado New Jersey Indiana Ohio Nevada Utah California Rhode IslandConnecticut Pennsylvania Illinois Massachusetts Nebraska...Evans US Army Hospital ( Colorado Springs, Colorado ) Colorado Springs, Colorado Denver, Colorado Camp Pendleton Naval Hospital (Camp Pendleton

  19. Mars Science Laboratory Sample Acquisition, Sample Processing and Handling: Subsystem Design and Test Challenges

    NASA Technical Reports Server (NTRS)

    Jandura, Louise

    2010-01-01

    The Sample Acquisition/Sample Processing and Handling subsystem for the Mars Science Laboratory is a highly-mechanized, Rover-based sampling system that acquires powdered rock and regolith samples from the Martian surface, sorts the samples into fine particles through sieving, and delivers small portions of the powder into two science instruments inside the Rover. SA/SPaH utilizes 17 actuated degrees-of-freedom to perform the functions needed to produce 5 sample pathways in support of the scientific investigation on Mars. Both hardware redundancy and functional redundancy are employed in configuring this sampling system so some functionality is retained even with the loss of a degree-of-freedom. Intentional dynamic environments are created to move sample while vibration isolators attenuate this environment at the sensitive instruments located near the dynamic sources. In addition to the typical flight hardware qualification test program, two additional types of testing are essential for this kind of sampling system: characterization of the intentionally-created dynamic environment and testing of the sample acquisition and processing hardware functions using Mars analog materials in a low pressure environment. The overall subsystem design and configuration are discussed along with some of the challenges, tradeoffs, and lessons learned in the areas of fault tolerance, intentional dynamic environments, and special testing

  20. Environmental Control and Life Support Integration Strategy for 6-Crew Operations

    NASA Technical Reports Server (NTRS)

    2009-01-01

    The International Space Station (ISS) crew compliment will be increasing in size from 3 to 6 crew members in the summer of 2009. In order to support this increase in crew on ISS, the United States on-orbit Segment (USOS) has been outfitted with a suite of regenerative Environmental Control and Life Support (ECLS) hardware including an Oxygen Generation System(OGS), Waste and Hygiene Compartment (WHC), and a Water Recovery System (WRS). The WRS includes the Urine Processor Assembly (UPA) and the Water Processor Assembly (WPA). A critical step in advancing to a 6Crew support capability on ISS is a full checkedout and verification of the Regenerative ECLS hardware. With a successful checkout, the ISS will achieve full redundancy in its onorbit life support system between the USOS and Russian Segment (RS). The additional redundancy created by the Regenerative ECLS hardware creates the opportunity for independent support capabilities between segments, and for the first time since the start of ISS, the necessity to revise Life Support strategy agreements. Independent operating strategies coupled with the loss of the Space Shuttle supply and return capabilities in 2010 offers additional challenges. These challenges create the need for a higher level of onorbit consumables reserve to ensure crewmember life support during a system failure. This paper will discuss the evolution of the ISS Life Support hardware strategy in support of 6Crew on ISS, as well as the continued work which will be necessary to ensure the support of crew and ISS Program objectives through the life of station.

  1. Online Learning: Addressing Challenges and Seizing Opportunities. Oregon

    ERIC Educational Resources Information Center

    Alliance for Excellent Education, 2010

    2010-01-01

    America's K-12 education system faces three significant challenges: (1) increased global demands for skilled workers, (2) significant financial shortfalls, and (3) a looming teacher shortage. Independently, these factors present significant challenges for U.S. schools. In combination, they create a national imperative for swift action to create a…

  2. Online Learning: Addressing Challenges and Seizing Opportunities. Minnesota

    ERIC Educational Resources Information Center

    Alliance for Excellent Education, 2010

    2010-01-01

    America's K-12 education system faces three significant challenges: (1) increased global demands for skilled workers, (2) significant financial shortfalls, and (3) a looming teacher shortage. Independently, these factors present significant challenges for U.S. schools. In combination, they create a national imperative for swift action to create a…

  3. Online Learning: Addressing Challenges and Seizing Opportunities. Idaho

    ERIC Educational Resources Information Center

    Alliance for Excellent Education, 2010

    2010-01-01

    America's K-12 education system faces three significant challenges: (1) increased global demands for skilled workers, (2) significant financial shortfalls, and (3) a looming teacher shortage. Independently, these factors present significant challenges for U.S. schools. In combination, they create a national imperative for swift action to create a…

  4. Online Learning: Addressing Challenges and Seizing Opportunities. New Mexico

    ERIC Educational Resources Information Center

    Alliance for Excellent Education, 2010

    2010-01-01

    America's K-12 education system faces three significant challenges: (1) increased global demands for skilled workers, (2) significant financial shortfalls, and (3) a looming teacher shortage. Independently, these factors present significant challenges for U.S. schools. In combination, they create a national imperative for swift action to create a…

  5. Online Learning: Addressing Challenges and Seizing Opportunities. New Hampshire

    ERIC Educational Resources Information Center

    Alliance for Excellent Education, 2010

    2010-01-01

    America's K-12 education system faces three significant challenges: (1) increased global demands for skilled workers, (2) significant financial shortfalls, and (3) a looming teacher shortage. Independently, these factors present significant challenges for U.S. schools. In combination, they create a national imperative for swift action to create a…

  6. Online Learning: Addressing Challenges and Seizing Opportunities. Hawaii

    ERIC Educational Resources Information Center

    Alliance for Excellent Education, 2010

    2010-01-01

    America's K-12 education system faces three significant challenges: (1) increased global demands for skilled workers, (2) significant financial shortfalls, and (3) a looming teacher shortage. Independently, these factors present significant challenges for U.S. schools. In combination, they create a national imperative for swift action to create a…

  7. Online Learning: Addressing Challenges and Seizing Opportunities. Wisconsin

    ERIC Educational Resources Information Center

    Alliance for Excellent Education, 2010

    2010-01-01

    America's K-12 education system faces three significant challenges: (1) increased global demands for skilled workers, (2) significant financial shortfalls, and (3) a looming teacher shortage. Independently, these factors present significant challenges for U.S. schools. In combination, they create a national imperative for swift action to create a…

  8. Moving the Journey Towards Independence: Adolescents Transitioning to Successful Diabetes Self-Management.

    PubMed

    Babler, Elizabeth; Strickland, Carolyn June

    2015-01-01

    To gain a greater understanding of adolescent's experiences living with Type 1 diabetes mellitus (T1DM) and create a theoretical paradigm. Grounded theory as described by Glaser was used. Fifteen in-depth interviews were conducted with adolescent's ages 11-15 with T1DM. Symbolic interactionism is the theoretical framework for grounded theory. Data were collected; transcribed, coded, and analyzed simultaneously using constant comparative analysis and findings were grounded in the words of participants. A theoretical model was created with the concept of "normalizing". Normalizing was defined as the ability to integrate diabetes into one's daily life to make diabetes 'part of me'. Phase four of the model, and the focus of this manuscript was "Moving the Journey towards Independence" and included: 1) taking over care, 2) experiencing conflict with parents, and 3) realizing diabetes is hard. The major task for adolescents in this phase was separating from parents to independently manage diabetes. The normalizing task for this phase was: "taking on the burden of care". Adolescents described challenges with independent care and increased parental conflict including: fearing needles, forgetting insulin, feeling embarrassed and believing that diabetes was a burden in their life. Additionally, juggling the multiple responsibilities of home, school and work along with managing a chronic illness during adolescence is challenging. Transitioning to diabetes self-management is a challenge for adolescents. This model advances understanding of the moving processes in adolescents transitioning; additionally, hypotheses are presented that may be used for developing interventions to promote success in self-management. Copyright © 2015 Elsevier Inc. All rights reserved.

  9. Moving the journey towards independence: Adolescents transitioning to successful diabetes self-management

    PubMed Central

    Strickland, C. June

    2016-01-01

    Purpose To gain a greater understanding of adolescent’s experiences living with Type 1 diabetes mellitus (T1DM) and create a theoretical paradigm. Methods Grounded theory as described by Glaser was used. Fifteen in-depth interviews were conducted with adolescent’s ages 11 to 15 with T1DM. Symbolic interactionism is the theoretical framework for grounded theory. Data were collected; transcribed, coded, and analyzed simultaneously using constant comparative analysis and findings were grounded in the words of participants. Results A theoretical model was created with the concept of “normalizing”. Normalizing was defined as the ability to integrate diabetes into one’s daily life to make diabetes ‘part of me’. Phase four of the model, and the focus of this manuscript was “Moving the Journey towards Independence” and included: 1) taking over care, 2) experiencing conflict with parents, and 3) realizing diabetes is hard. The major task for adolescents in this phase was separating from parents to independently manage diabetes. The normalizing task for this phase was: “taking on the burden of care”. Adolescents described challenges with independent care and increased parental conflict including: fearing needles, forgetting insulin, feeling embarrassed and believing that diabetes was a burden in their life. Additionally, juggling the multiple responsibilities of home, school and work along with managing a chronic illness during adolescence is challenging. Conclusions Transitioning to diabetes self-management is a challenge for adolescents. This model advances understanding of the moving processes in adolescents transitioning; additionally, hypotheses are presented that may be used for developing interventions to promote success in self-management. PMID:26190456

  10. A method to estimate the additional uncertainty in gap-filled NEE resulting from long gaps in the CO2 flux record

    Treesearch

    Andrew D. Richardson; David Y. Hollinger

    2007-01-01

    Missing values in any data set create problems for researchers. The process by which missing values are replaced, and the data set is made complete, is generally referred to as imputation. Within the eddy flux community, the term "gap filling" is more commonly applied. A major challenge is that random errors in measured data result in uncertainty in the gap-...

  11. Transforming your professional self: encouraging lifelong personal and professional growth.

    PubMed

    Rodts, Mary F; Lamb, Karen V

    2008-01-01

    Transforming from student nurse to registered nurse is often discussed in a capstone class or a hospital orientation program. Changes in professional plans later in the career continuum often occur, but are not always planned. This article discusses the challenges of change, the need for career planning, stages of role acquisition, role socialization, and role transformation. In addition, it outlines the importance of creating a career plan to meet future career goals.

  12. Towards addressing transient learning challenges in undergraduate physics: an example from electrostatics

    NASA Astrophysics Data System (ADS)

    Fredlund, T.; Linder, C.; Airey, J.

    2015-09-01

    In this article we characterize transient learning challenges as learning challenges that arise out of teaching situations rather than conflicts with prior knowledge. We propose that these learning challenges can be identified by paying careful attention to the representations that students produce. Once a transient learning challenge has been identified, teachers can create interventions to address it. By illustration, we argue that an appropriate way to design such interventions is to create variation around the disciplinary-relevant aspects associated with the transient learning challenge.

  13. Power System Challenge: Synthesis Report for the 7th Clean Energy Ministerial

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    None, None

    The Clean Energy Ministerial's (CEM's) Power System Challenge was established in 2015 to create a shared vision among major economies regarding the pathway to clean, reliable, resilient, and affordable power. Endorsing governments have created core principles and challenge propositions as a framework for government and industry action to support and guide power system transformation. This brochure details the status of the Challenge, how countries are working to meet the Challenge, and the relevant milestones reached by initiatives of the Clean Energy Ministerial.

  14. Fluid-structure interaction modeling of clusters of spacecraft parachutes with modified geometric porosity

    NASA Astrophysics Data System (ADS)

    Takizawa, Kenji; Tezduyar, Tayfun E.; Boben, Joseph; Kostov, Nikolay; Boswell, Cody; Buscher, Austin

    2013-12-01

    To increase aerodynamic performance, the geometric porosity of a ringsail spacecraft parachute canopy is sometimes increased, beyond the "rings" and "sails" with hundreds of "ring gaps" and "sail slits." This creates extra computational challenges for fluid-structure interaction (FSI) modeling of clusters of such parachutes, beyond those created by the lightness of the canopy structure, geometric complexities of hundreds of gaps and slits, and the contact between the parachutes of the cluster. In FSI computation of parachutes with such "modified geometric porosity," the flow through the "windows" created by the removal of the panels and the wider gaps created by the removal of the sails cannot be accurately modeled with the Homogenized Modeling of Geometric Porosity (HMGP), which was introduced to deal with the hundreds of gaps and slits. The flow needs to be actually resolved. All these computational challenges need to be addressed simultaneously in FSI modeling of clusters of spacecraft parachutes with modified geometric porosity. The core numerical technology is the Stabilized Space-Time FSI (SSTFSI) technique, and the contact between the parachutes is handled with the Surface-Edge-Node Contact Tracking (SENCT) technique. In the computations reported here, in addition to the SSTFSI and SENCT techniques and HMGP, we use the special techniques we have developed for removing the numerical spinning component of the parachute motion and for restoring the mesh integrity without a remesh. We present results for 2- and 3-parachute clusters with two different payload models.

  15. The New Global Responsibilities of Engineers Create Challenges for Engineering Education

    ERIC Educational Resources Information Center

    Fuchs, Willi

    2012-01-01

    Modern societies aim to solve the global challenges of the 21st century with sustainable solutions such as resource efficiency, use of renewable energy sources and recycling. Engineers are called upon to create the cutting edge technological solutions that can help to address these challenges. In developed as well as in developing countries,…

  16. How to Store Energy Fast

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Augustyn, Veronica; Ko, Jesse; Rauda, Iris

    Representing the Molecularly Engineered Energy Materials (MEEM), this document is one of the entries in the Ten Hundred and One Word Challenge. As part of the challenge, the 46 Energy Frontier Research Centers were invited to represent their science in images, cartoons, photos, words and original paintings, but any descriptions or words could only use the 1000 most commonly used words in the English language, with the addition of one word important to each of the EFRCs and the mission of DOE energy. The mission of MEEM, using inexpensive custom-designed molecular building blocks, aims to create revolutionary new materials withmore » self-assembled multi-scale architectures that will enable high performing energy generation and storage applications.« less

  17. Soft Sun Cells

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Shastry, Tejas

    Representing the Argonne-Northwestern Solar Energy Research (ANSER) Center, this document is one of the entries in the Ten Hundred and One Word Challenge. As part of the challenge, the 46 Energy Frontier Research Centers were invited to represent their science in images, cartoons, photos, words and original paintings, but any descriptions or words could only use the 1000 most commonly used words in the English language, with the addition of one word important to each of the EFRCs and the mission of DOE: energy. The mission of ANSER is to revolutionize our understanding of molecules, materials and methods necessary tomore » create dramatically more efficient technologies for solar fuels and electricity production.« less

  18. Bioprinting toward organ fabrication: challenges and future trends.

    PubMed

    Ozbolat, Ibrahim T; Yu, Yin

    2013-03-01

    Tissue engineering has been a promising field of research, offering hope for bridging the gap between organ shortage and transplantation needs. However, building three-dimensional (3-D) vascularized organs remains the main technological barrier to be overcome. Organ printing, which is defined as computer-aided additive biofabrication of 3-D cellular tissue constructs, has shed light on advancing this field into a new era. Organ printing takes advantage of rapid prototyping (RP) technology to print cells, biomaterials, and cell-laden biomaterials individually or in tandem, layer by layer, directly creating 3-D tissue-like structures. Here, we overview RP-based bioprinting approaches and discuss the current challenges and trends toward fabricating living organs for transplant in the near future.

  19. Participatory Democracy, Community Organizing and the Community Assessment of Freeway Exposure and Health (CAFEH) Partnership

    PubMed Central

    Sprague Martinez, Linda; Reisner, Ellin; Campbell, Maria; Brugge, Doug

    2017-01-01

    Background: Conflicting interests, power imbalance and relationships characterized by distrust are just a few of the many challenges community–academic research partnerships face. In addition, the time it takes to build relationships is often overlooked, which further complicates matters and can leave well-intentioned individuals re-creating oppressive conditions through inauthentic partnerships. This paper presents a novel approach of using meeting minutes to explore partnership dynamics. The Community Assessment of Freeway Exposure and Health (CAFEH) partnership is used as an illustrative case study to identify how community academic partnerships overcome the challenges associated with community-based participatory research (CBPR). CAFEH is a study of ultrafine particle exposure (UFP) near highways in the Boston, MA area. Methods: Qualitative analysis was applied to meeting minutes and process evaluation reports from the first three years of the CAFEH study (n = 73 files). In addition, a group meeting was held with project partners in order to contextualize the findings from the document analysis. Results: The three most commonly referenced challenges included language barriers, the overall project structure and budgetary constraints. Meanwhile, a heavy emphasis on process and an approach steeped in participatory democracy facilitated CAFEH’s ability to overcome these challenges, as well as sustain and augment strong partnership ties. Conclusions: This experience suggests that leadership that incorporates an organizing approach and a transformational style facilitates CBPR processes and helps teams surmount challenges. PMID:28165418

  20. Participatory Democracy, Community Organizing and the Community Assessment of Freeway Exposure and Health (CAFEH) Partnership.

    PubMed

    Sprague Martinez, Linda; Reisner, Ellin; Campbell, Maria; Brugge, Doug

    2017-02-04

    Background: Conflicting interests, power imbalance and relationships characterized by distrust are just a few of the many challenges community-academic research partnerships face. In addition, the time it takes to build relationships is often overlooked, which further complicates matters and can leave well-intentioned individuals re-creating oppressive conditions through inauthentic partnerships. This paper presents a novel approach of using meeting minutes to explore partnership dynamics. The Community Assessment of Freeway Exposure and Health (CAFEH) partnership is used as an illustrative case study to identify how community academic partnerships overcome the challenges associated with community-based participatory research (CBPR). CAFEH is a study of ultrafine particle exposure (UFP) near highways in the Boston, MA area. Methods: Qualitative analysis was applied to meeting minutes and process evaluation reports from the first three years of the CAFEH study ( n = 73 files). In addition, a group meeting was held with project partners in order to contextualize the findings from the document analysis. Results: The three most commonly referenced challenges included language barriers, the overall project structure and budgetary constraints. Meanwhile, a heavy emphasis on process and an approach steeped in participatory democracy facilitated CAFEH's ability to overcome these challenges, as well as sustain and augment strong partnership ties. Conclusions: This experience suggests that leadership that incorporates an organizing approach and a transformational style facilitates CBPR processes and helps teams surmount challenges.

  1. Screening women for intimate partner violence: Creating proper practice habits.

    PubMed

    Knox, Beth

    2018-05-17

    Intimate partner violence continues to be a challenge for advanced practice registered nurses to address and manage in their daily practice. This article reviews current healthcare concerns in heterosexual, bisexual, transgender, and lesbian women, and explores screening guidelines and resources for developing successful screening habits. Additionally, the article discusses how the Transtheoretical Model and Stages of Change offers insight into the behavior of women who experience intimate partner violence and provides safety strategies for these women.

  2. Laboratory medicine: challenges and opportunities.

    PubMed

    Bossuyt, Xavier; Verweire, Kurt; Blanckaert, Norbert

    2007-10-01

    Technologic innovations have substantially improved the productivity of clinical laboratories, but the services provided by clinical laboratories are increasingly becoming commoditized. We reflect on how current developments may affect the future of laboratory medicine and how to deal with these changes. We argue that to be prepared for the future, clinical laboratories should enhance efficiency and reduce costs by forming alliances and networks; consolidating, integrating, or outsourcing; and more importantly, create additional value by providing knowledge services related to in vitro diagnostics.

  3. Competence development for the promotion of gender equality in development cooperation: the case of the Swedish International Development Cooperation Agency (SIDA).

    PubMed

    Hannan-andersson, C

    1997-01-01

    The Swedish International Development Cooperation Agency (SIDA) has created an Action Program for Promoting Equality Between Women and Men in Partner Countries that emphasizes competency development as a means of achieving gender equality. Competency development goes beyond formal training and utilizes existing entry points while creating innovative ones. SIDA's partnership approach requires clear delineation of roles for SIDA personnel and partner countries, with SIDA 1) applying a gender perspective to assessments, 2) initiating a constructive dialogue about gender equality if needed, 3) assessing the need for gender equality promoting competency development, 4) studying the local context, and 5) developing effective local networks. In addition, the needs of different groups within SIDA should be met with appropriate competency development inputs while SIDA continues support to competency development in partner countries by developing local capacity for gender training and gender sensitization at the regional and national levels. At SIDA, gender training has evolved since 1989 to its current focus on the practical and concrete challenges facing participants. In addition, departments and divisions conduct sector- and issue-specific training, and gender equality is integrated in all SIDA training activities on every topic. The challenges for future competency development are to 1) increase the number of men involved in provision of competency development inputs, 2) improve competency at embassy and field levels, and 3) improve competency in policy dialogues.

  4. OCT Expanded Clinical Data Analysis

    NASA Technical Reports Server (NTRS)

    Van Baalen, Mary; Tafreshi, Ali; Patel, Nimesh; Young, Millennia; Mason, Sara; Otto, Christian; Samuels, Brian; Koslovsky, Matthew; Schaefer, Caroline; Taiym, Wafa; hide

    2017-01-01

    Vision changes identified in long duration space fliers has led to a more comprehensive clinical monitoring protocol. Optical Coherence Tomography (OCT) was recently implemented on board the International Space Station in 2013. NASA is collaborating with Heidelberg Engineering to expand our current OCT data analysis capability by implementing a volumetric approach. Volumetric maps will be created by combining the circle scan, the disc block scan, and the radial scan. This assessment may provide additional information about the optic nerve and further characterize changes related microgravity exposure. We will discuss challenges with collection and analysis of OCT data, present the results of this reanalysis and outline the potential benefits and limitations of the additional data.

  5. Open otoplasty.

    PubMed

    Nordzell, B

    2000-12-01

    The fundamental challenge in correcting protruding ears is to create an anthelix fold that has a natural appearance: evenly rounded and without sharp edges. More or less favorable results have been reached using different methods of excision, superficial incision, suturing, and cartilage tubing. A good method must also fulfill some additional requirements. It must be simple and not too time-consuming. In addition, it should be comfortable for the patient, easily adapted to different anatomical conditions, and have a minimal recurrence rate. The following technique to be described has been used by the author for more than 30 years. He has operated on approximately 870 patients with the open technique. In this article, the last 80 consecutive patients are reported after their follow-up visits. Over the years, the technique has been modified in some details. The auricular cartilage is incised along the lateral border of the anthelical fold. The entire anterior surface of the anthelix is dissected free and abraded. The cartilage bends backward, and a natural anthelix fold is created.

  6. Patients’ Online Access to Their Primary Care Electronic Health Records and Linked Online Services: Implications for Research and Practice

    PubMed Central

    Mold, Freda; de Lusignan, Simon

    2015-01-01

    Online access to medical records and linked services, including requesting repeat prescriptions and booking appointments, enables patients to personalize their access to care. However, online access creates opportunities and challenges for both health professionals and their patients, in practices and in research. The challenges for practice are the impact of online services on workload and the quality and safety of health care. Health professionals are concerned about the impact on workload, especially from email or other online enquiry systems, as well as risks to privacy. Patients report how online access provides a convenient means through which to access their health provider and may offer greater satisfaction if they get a timely response from a clinician. Online access and services may also result in unforeseen consequences and may change the nature of the patient-clinician interaction. Research challenges include: (1) Ensuring privacy, including how to control inappropriate carer and guardian access to medical records; (2) Whether online access to records improves patient safety and health outcomes; (3) Whether record access increases disparities across social classes and between genders; and (4) Improving efficiency. The challenges for practice are: (1) How to incorporate online access into clinical workflow; (2) The need for a business model to fund the additional time taken. Creating a sustainable business model for a safe, private, informative, more equitable online service is needed if online access to records is to be provided outside of pay-for-service systems. PMID:26690225

  7. Patients' Online Access to Their Primary Care Electronic Health Records and Linked Online Services: Implications for Research and Practice.

    PubMed

    Mold, Freda; de Lusignan, Simon

    2015-12-04

    Online access to medical records and linked services, including requesting repeat prescriptions and booking appointments, enables patients to personalize their access to care. However, online access creates opportunities and challenges for both health professionals and their patients, in practices and in research. The challenges for practice are the impact of online services on workload and the quality and safety of health care. Health professionals are concerned about the impact on workload, especially from email or other online enquiry systems, as well as risks to privacy. Patients report how online access provides a convenient means through which to access their health provider and may offer greater satisfaction if they get a timely response from a clinician. Online access and services may also result in unforeseen consequences and may change the nature of the patient-clinician interaction. Research challenges include: (1) Ensuring privacy, including how to control inappropriate carer and guardian access to medical records; (2) Whether online access to records improves patient safety and health outcomes; (3) Whether record access increases disparities across social classes and between genders; and (4) Improving efficiency. The challenges for practice are: (1) How to incorporate online access into clinical workflow; (2) The need for a business model to fund the additional time taken. Creating a sustainable business model for a safe, private, informative, more equitable online service is needed if online access to records is to be provided outside of pay-for-service systems.

  8. Friction Stir Additive Manufacturing: Route to High Structural Performance

    NASA Astrophysics Data System (ADS)

    Palanivel, S.; Sidhar, H.; Mishra, R. S.

    2015-03-01

    Aerospace and automotive industries provide the next big opportunities for additive manufacturing. Currently, the additive industry is confronted with four major challenges that have been identified in this article. These challenges need to be addressed for the additive technologies to march into new frontiers and create additional markets. Specific potential success in the transportation sectors is dependent on the ability to manufacture complicated structures with high performance. Most of the techniques used for metal-based additive manufacturing are fusion based because of their ability to fulfill the computer-aided design to component vision. Although these techniques aid in fabrication of complex shapes, achieving high structural performance is a key problem due to the liquid-solid phase transformation. In this article, friction stir additive manufacturing (FSAM) is shown as a potential solid-state process for attaining high-performance lightweight alloys for simpler geometrical applications. To illustrate FSAM as a high-performance route, manufactured builds of Mg-4Y-3Nd and AA5083 are shown as examples. In the Mg-based alloy, an average hardness of 120 HV was achieved in the built structure and was significantly higher than that of the base material (97 HV). Similarly for the Al-based alloy, compared with the base hardness of 88 HV, the average built hardness was 104 HV. A potential application of FSAM is illustrated by taking an example of a simple stiffener assembly.

  9. Hydrogel scaffolds for tissue engineering: Progress and challenges

    PubMed Central

    El-Sherbiny, Ibrahim M.; Yacoub, Magdi H.

    2013-01-01

    Designing of biologically active scaffolds with optimal characteristics is one of the key factors for successful tissue engineering. Recently, hydrogels have received a considerable interest as leading candidates for engineered tissue scaffolds due to their unique compositional and structural similarities to the natural extracellular matrix, in addition to their desirable framework for cellular proliferation and survival. More recently, the ability to control the shape, porosity, surface morphology, and size of hydrogel scaffolds has created new opportunities to overcome various challenges in tissue engineering such as vascularization, tissue architecture and simultaneous seeding of multiple cells. This review provides an overview of the different types of hydrogels, the approaches that can be used to fabricate hydrogel matrices with specific features and the recent applications of hydrogels in tissue engineering. Special attention was given to the various design considerations for an efficient hydrogel scaffold in tissue engineering. Also, the challenges associated with the use of hydrogel scaffolds were described. PMID:24689032

  10. Expanding the Parameters for Excellence in Patient Assignments: Is Leveraging an Evidence-Data-Based Acuity Methodology Realistic?

    PubMed

    Gray, Joel; Kerfoot, Karlene

    2016-01-01

    Finding the balance of equitable assignments continues to be a challenge for health care organizations seeking to leverage evidence-based leadership practices. Ratios and subjective acuity strategies for nurse-patient staffing continue to be the dominant approach in health care organizations. In addition to ratio-based assignments and acuity-based assignment models driven by financial targets, more emphasis on using evidence-based leadership strategies to manage and create science for effective staffing is needed. In particular, nurse leaders are challenged to increase the sophistication of management of patient turnover (admissions, discharges, and transfers) and integrate tools from Lean methodologies and quality management strategies to determine the effectiveness of nurse-patient staffing.

  11. Creating developmentally auspicious school environments for African American boys.

    PubMed

    Barbarin, Oscar A; Chinn, Lisa; Wright, Yamanda F

    2014-01-01

    African American (AA) boys face serious barriers to academic success, many of which are uncommon--or absent--in the lives of AA girls, other children of color, and European American children. In this chapter, we identify nine critical challenges to the successful education of AA boys and review possible solutions. In addition, we evaluate one particular reform, public single-sex schooling, as a possible solution to the challenges facing AA boys. Considering the evidence, we argue that recent efforts to expand the existence of public single-sex schools are rarely grounded in empirical findings. Given the lack of compelling evidence and the high stakes for AA boys, we call for more rigorous evaluations of the outcomes of sex-segregated programs that specifically target AA boys.

  12. Female genital cutting: confronting cultural challenges and health complications across the lifespan.

    PubMed

    Farage, Miranda A; Miller, Kenneth W; Tzeghai, Ghebre E; Azuka, Charles E; Sobel, Jack D; Ledger, William J

    2015-01-01

    Female genital cutting affects over 140 million women worldwide. Prevalent in certain countries of Africa and the Middle East, the practice continues among immigrants to industrialized countries. Female genital cutting is a deeply rooted tradition that confers honor on a woman and her family, yet also a traumatic experience that creates significant dermatological, gynecological, obstetric and infectious disease complications. Little is known about postmenopausal health in cut women. The international community views this practice as a human rights violation. In addition to genital health complications, the medical community must confront an understudied concern of what happens as this population ages. These challenges must be addressed to provide optimal care to women affected by female genital cutting.

  13. Fluid{Structure Interaction Modeling of Modified-Porosity Parachutes and Parachute Clusters

    NASA Astrophysics Data System (ADS)

    Boben, Joseph J.

    To increase aerodynamic performance, the geometric porosity of a ringsail spacecraft parachute canopy is sometimes increased, beyond the "rings" and "sails" with hundreds of "ring gaps" and "sail slits." This creates extra computational challenges for fluid-structure interaction (FSI) modeling of clusters of such parachutes, beyond those created by the lightness of the canopy structure, geometric complexities of hundreds of gaps and slits, and the contact between the parachutes of the cluster. In FSI computation of parachutes with such "modified geometric porosity," the ow through the "windows" created by the removal of the panels and the wider gaps created by the removal of the sails cannot be accurately modeled with the Homogenized Modeling of Geometric Porosity (HMGP), which was introduced to deal with the hundreds of gaps and slits. The ow needs to be actually resolved. All these computational challenges need to be addressed simultaneously in FSI modeling of clusters of spacecraft parachutes with modified geometric porosity. The core numerical technology is the Stabilized Space-Time FSI (SSTFSI) technique, and the contact between the parachutes is handled with the Surface-Edge-Node Contact Tracking (SENCT) technique. In the computations reported here, in addition to the SSTFSI and SENCT techniques and HMGP, we use the special techniques we have developed for removing the numerical spinning component of the parachute motion and for restoring the mesh integrity without a remesh. We present results for 2- and 3-parachute clusters with two different payload models. We also present the FSI computations we carried out for a single, subscale modified-porosity parachute.

  14. Laser Ultrasound Spectroscopy Scanning for 3D Printed Parts

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Brennan, Guendalyn Kendra

    One of the challenges of additive manufacturing is quality control due to the possibility of unseen flaws in the final product. The current methods of inspection are lacking in detail, too slow for practical use, or unable to validate internal structure. This report examines the use of laser ultrasound spectroscopy in layer by layer scans of 3D printed parts as they are created. The result is fast and detailed quality control. An additional advantage of this method is the ability to cancel a print as soon as a defect is detected, therefore saving materials and time. This technique, though simplemore » in concept, has been a challenge to implement. I discuss tweaking the 3D printer configuration, and finding the optimal settings for laser scanning small parts made of ABS plastic, as well as the limits of how small of a detail the laser can detect. These settings include the frequency of the ultrasonic transducer, the speed of the laser, and the distance from the laser to the part.« less

  15. System engineering and science projects: lessons from MeerKAT

    NASA Astrophysics Data System (ADS)

    Kapp, Francois

    2016-08-01

    The Square Kilometre Array (SKA) is a large science project planning to commence construction of the world's largest Radio Telescope after 2018. MeerKAT is one of the precursor projects to the SKA, based on the same site that will host the SKA Mid array in the central Karoo area of South Africa. From the perspective of signal processing hardware development, we analyse the challenges that MeerKAT encountered and extrapolate them to SKA in order to prepare the System Engineering and Project Management methods that could contribute to a successful completion of SKA. Using the MeerKAT Digitiser, Correlator/Beamformer and Time and Frequency Reference Systems as an example, we will trace the risk profile and subtle differences in engineering approaches of these systems over time and show the effects of varying levels of System Engineering rigour on the evolution of their risk profiles. It will be shown that the most rigorous application of System Engineering discipline resulted in the most substantial reduction in risk over time. Since the challenges faced by SKA are not limited to that of MeerKAT, we also look into how that translates to a system development where there is substantial complexity in both the created system as well as the creating system. Since the SKA will be designed and constructed by consortia made up from the ten member countries, there are many additional complexities to the organisation creating the system - a challenge the MeerKAT project did not encounter. Factors outside of engineering, for instance procurement models and political interests, also play a more significant role, and add to the project risks of SKA when compared to MeerKAT.

  16. Additive Manufacturing of Tooling for Refrigeration Cabinet Foaming Processes

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Post, Brian K; Nuttall, David; Cukier, Michael

    The primary objective of this project was to leverage the Big Area Additive Manufacturing (BAAM) process and materials into a long term, quick change tooling concept to drastically reduce product lead and development timelines and costs. Current refrigeration foam molds are complicated to manufacture involving casting several aluminum parts in an approximate shape, machining components of the molds and post fitting and shimming of the parts in an articulated fixture. The total process timeline can take over 6 months. The foaming process is slower than required for production, therefore multiple fixtures, 10 to 27, are required per refrigerator model. Moldsmore » are particular to a specific product configuration making mixed model assembly challenging for sequencing, mold changes or auto changeover features. The initial goal was to create a tool leveraging the ORNL materials and additive process to build a tool in 4 to 6 weeks or less. A secondary goal was to create common fixture cores and provide lightweight fixture sections that could be revised in a very short time to increase equipment flexibility reduce lead times, lower the barriers to first production trials, and reduce tooling costs.« less

  17. Ensemble method for dengue prediction.

    PubMed

    Buczak, Anna L; Baugher, Benjamin; Moniz, Linda J; Bagley, Thomas; Babin, Steven M; Guven, Erhan

    2018-01-01

    In the 2015 NOAA Dengue Challenge, participants made three dengue target predictions for two locations (Iquitos, Peru, and San Juan, Puerto Rico) during four dengue seasons: 1) peak height (i.e., maximum weekly number of cases during a transmission season; 2) peak week (i.e., week in which the maximum weekly number of cases occurred); and 3) total number of cases reported during a transmission season. A dengue transmission season is the 12-month period commencing with the location-specific, historical week with the lowest number of cases. At the beginning of the Dengue Challenge, participants were provided with the same input data for developing the models, with the prediction testing data provided at a later date. Our approach used ensemble models created by combining three disparate types of component models: 1) two-dimensional Method of Analogues models incorporating both dengue and climate data; 2) additive seasonal Holt-Winters models with and without wavelet smoothing; and 3) simple historical models. Of the individual component models created, those with the best performance on the prior four years of data were incorporated into the ensemble models. There were separate ensembles for predicting each of the three targets at each of the two locations. Our ensemble models scored higher for peak height and total dengue case counts reported in a transmission season for Iquitos than all other models submitted to the Dengue Challenge. However, the ensemble models did not do nearly as well when predicting the peak week. The Dengue Challenge organizers scored the dengue predictions of the Challenge participant groups. Our ensemble approach was the best in predicting the total number of dengue cases reported for transmission season and peak height for Iquitos, Peru.

  18. Ensemble method for dengue prediction

    PubMed Central

    Baugher, Benjamin; Moniz, Linda J.; Bagley, Thomas; Babin, Steven M.; Guven, Erhan

    2018-01-01

    Background In the 2015 NOAA Dengue Challenge, participants made three dengue target predictions for two locations (Iquitos, Peru, and San Juan, Puerto Rico) during four dengue seasons: 1) peak height (i.e., maximum weekly number of cases during a transmission season; 2) peak week (i.e., week in which the maximum weekly number of cases occurred); and 3) total number of cases reported during a transmission season. A dengue transmission season is the 12-month period commencing with the location-specific, historical week with the lowest number of cases. At the beginning of the Dengue Challenge, participants were provided with the same input data for developing the models, with the prediction testing data provided at a later date. Methods Our approach used ensemble models created by combining three disparate types of component models: 1) two-dimensional Method of Analogues models incorporating both dengue and climate data; 2) additive seasonal Holt-Winters models with and without wavelet smoothing; and 3) simple historical models. Of the individual component models created, those with the best performance on the prior four years of data were incorporated into the ensemble models. There were separate ensembles for predicting each of the three targets at each of the two locations. Principal findings Our ensemble models scored higher for peak height and total dengue case counts reported in a transmission season for Iquitos than all other models submitted to the Dengue Challenge. However, the ensemble models did not do nearly as well when predicting the peak week. Conclusions The Dengue Challenge organizers scored the dengue predictions of the Challenge participant groups. Our ensemble approach was the best in predicting the total number of dengue cases reported for transmission season and peak height for Iquitos, Peru. PMID:29298320

  19. Composites of 3D-Printed Polymers and Textile Fabrics*

    NASA Astrophysics Data System (ADS)

    Martens, Yasmin; Ehrmann, Andrea

    2017-08-01

    3D printing belongs to the rapidly emerging technologies of our time. Due to its recent drawback - the technology is relatively slow compared with other primary shaping methods, such as injection molding -, 3D printing is often not used for creating complete large components but to add specific features to existing larger objects. One of the possibilities to create such composites with an additional value consists in combining 3D printed polymers with textile fabrics. Several attempts have been made to enhance the adhesion between both materials, a task which is still challenging for diverse material combinations. Our paper reports about new experiments combining 3D printed embossed designs, snap fasteners and zip fasteners with different textile base materials, showing the possibilities and technical limits of these novel composites.

  20. Parenting and the Process of Migration: Possibilities within South Asian Families

    ERIC Educational Resources Information Center

    Deepak, Anne C.

    2005-01-01

    The migration experience creates a unique set of challenges for families, which can result in intergenerational conflict and create the conditions for abuse or neglect. Alternatively, families can cope with these challenges in creative and seemingly contradictory ways, thus strengthening family relationships. This article introduces the process of…

  1. Evaluation of target efficiencies for solid-liquid separation steps in biofuels production.

    PubMed

    Kochergin, Vadim; Miller, Keith

    2011-01-01

    Development of liquid biofuels has entered a new phase of large scale pilot demonstration. A number of plants that are in operation or under construction face the task of addressing the engineering challenges of creating a viable plant design, scaling up and optimizing various unit operations. It is well-known that separation technologies account for 50-70% of both capital and operating cost. Additionally, reduction of environmental impact creates technological challenges that increase project cost without adding to the bottom line. Different technologies vary in terms of selection of unit operations; however, solid-liquid separations are likely to be a major contributor to the overall project cost. Despite the differences in pretreatment approaches, similar challenges arise for solid-liquid separation unit operations. A typical process for ethanol production from biomass includes several solid-liquid separation steps, depending on which particular stream is targeted for downstream processing. The nature of biomass-derived materials makes it either difficult or uneconomical to accomplish complete separation in a single step. Therefore, setting realistic efficiency targets for solid-liquid separations is an important task that influences overall process recovery and economics. Experimental data will be presented showing typical characteristics for pretreated cane bagasse at various stages of processing into cellulosic ethanol. Results of generic material balance calculations will be presented to illustrate the influence of separation target efficiencies on overall process recoveries and characteristics of waste streams.

  2. Change and Hope in Physics

    NASA Astrophysics Data System (ADS)

    Goradia, Shantilal

    2009-05-01

    Physics = Ideas + Analyses. Newton reconciled Kepler's laws, Einstein's GR reconciled action at a distance. Our Planck Scale Statistics (see v3 and v4 of [1]) is a change that reconciles gravity with quantum physics simply. It does what a change should do and I will answer your questions again. It completes TOE, so what? There should not be any fear about disappearance of challenges. It will create other challenges to occupy creative physicists meaningfully. Physicists score highest on GRE score with the exception of mechanical engineers. They will come up with ideas applicable to other sectors like energy and economy. Newton, also a gold mine executive, introduced annuity for life, an insurance feature of social security. Here, I try one bold suggestion to illustrate the point. Putting 10% tax on new housing permits would raise the price of each house in the USA by an average of 2 x 10^4 dollars generating a wealth of 2x10^12 dollars for existing 10^8 houses, encouraging people to stick to their houses, inviting investors to grab existing houses, discouraging new construction which goes against the sale of existing houses, and injecting two trillion dollars in the economy without creating a deficit budget. The hope is that this change would challenge other high GRE scorers to come up with additional ideas. It is imaginative minds that solve problems, not subjective knowledge. [1] http://www.arXiv.org/pdf/physics/0210040.

  3. Challenges and Opportunities for Tribal Waters: Addressing Disparities in Safe Public Drinking Water on the Crow Reservation in Montana, USA.

    PubMed

    Doyle, John T; Kindness, Larry; Realbird, James; Eggers, Margaret J; Camper, Anne K

    2018-03-21

    Disparities in access to safe public drinking water are increasingly being recognized as contributing to health disparities and environmental injustice for vulnerable communities in the United States. As the Co-Directors of the Apsaálooke Water and Wastewater Authority (AWWWA) for the Crow Tribe, with our academic partners, we present here the multiple and complex challenges we have addressed in improving and maintaining tribal water and wastewater infrastructure, including the identification of diverse funding sources for infrastructure construction, the need for many kinds of specialized expertise and long-term stability of project personnel, ratepayer difficulty in paying for services, an ongoing legacy of inadequate infrastructure planning, and lack of water quality research capacity. As a tribal entity, the AWWWA faces additional challenges, including the complex jurisdictional issues affecting all phases of our work, lack of authority to create water districts, and additional legal and regulatory gaps-especially with regards to environmental protection. Despite these obstacles, the AWWWA and Crow Tribe have successfully upgraded much of the local water and wastewater infrastructure. We find that ensuring safe public drinking water for tribal and other disadvantaged U.S. communities will require comprehensive, community-engaged approaches across a broad range of stakeholders to successfully address these complex legal, regulatory, policy, community capacity, and financial challenges.

  4. Challenges and Opportunities for Tribal Waters: Addressing Disparities in Safe Public Drinking Water on the Crow Reservation in Montana, USA

    PubMed Central

    Doyle, John T.; Kindness, Larry; Realbird, James; Camper, Anne K.

    2018-01-01

    Disparities in access to safe public drinking water are increasingly being recognized as contributing to health disparities and environmental injustice for vulnerable communities in the United States. As the Co-Directors of the Apsaálooke Water and Wastewater Authority (AWWWA) for the Crow Tribe, with our academic partners, we present here the multiple and complex challenges we have addressed in improving and maintaining tribal water and wastewater infrastructure, including the identification of diverse funding sources for infrastructure construction, the need for many kinds of specialized expertise and long-term stability of project personnel, ratepayer difficulty in paying for services, an ongoing legacy of inadequate infrastructure planning, and lack of water quality research capacity. As a tribal entity, the AWWWA faces additional challenges, including the complex jurisdictional issues affecting all phases of our work, lack of authority to create water districts, and additional legal and regulatory gaps—especially with regards to environmental protection. Despite these obstacles, the AWWWA and Crow Tribe have successfully upgraded much of the local water and wastewater infrastructure. We find that ensuring safe public drinking water for tribal and other disadvantaged U.S. communities will require comprehensive, community-engaged approaches across a broad range of stakeholders to successfully address these complex legal, regulatory, policy, community capacity, and financial challenges. PMID:29561815

  5. The Online Learning Imperative: A Solution to Three Looming Crises in Education

    ERIC Educational Resources Information Center

    Wise, Bob

    2010-01-01

    Currently, K-12 education in the United States is dealing with three major challenges: (1) global skill demands versus educational attainment; (2) the funding cliff; and (3) a looming teacher shortage. Independently, these factors present significant challenges. In combination, they create a national imperative for swift action to create a more…

  6. Speeding Up Team Learning.

    ERIC Educational Resources Information Center

    Edmondson, Amy; Bohmer, Richard; Pisano, Gary

    2001-01-01

    A study of 16 cardiac surgery teams looked at how the teams adapted to new ways of working. The challenge of team management is to implement new processes as quickly as possible. Steps for creating a learning team include selecting a mix of skills and expertise, framing the challenge, and creating an environment of psychological safety. (JOW)

  7. Value-Creating Networks: Organizational Issues and Challenges

    ERIC Educational Resources Information Center

    Allee, Verna

    2009-01-01

    Purpose: The purpose of this paper is to provide examples of evaluating value-creating networks and to address the organizational issues and challenges of a network orientation. Design/methodology/approach: Value network analysis was first developed in 1993 and was adapted in 1997 for intangible asset management. It has been applied from shopfloor…

  8. Medication Assisted Treatment Research with Criminal Justice Populations: Challenges of Implementation

    PubMed Central

    Gordon, Michael S.; Kinlock, Timothy W.; Miller, Patrice M.

    2011-01-01

    Creating, implementing and evaluating substance abuse interventions, especially medication-assisted treatments, for prisoners, parolees, and probationers with histories of heroin addiction is an especially challenging endeavor because of the difficulty in coordinating and achieving cooperation among diverse criminal justice, substance abuse treatment, research, and social service agencies, each with its own priorities and agenda. In addition, there are special rules that must be followed when conducting research with criminal justice-involved populations, particularly prisoners. The following case studies will explore the authors’ experience of over 10 years conducting pharmacotherapy research using methadone, buprenorphine, and naltrexone with criminal justice populations. The major obstacles and how they were overcome are presented. Finally, recommendations are provided with regard to implementing and conducting research with criminal justice populations. PMID:22086665

  9. Challenges in Real-Time Prediction of Infectious Disease: A Case Study of Dengue in Thailand

    PubMed Central

    Lauer, Stephen A.; Sakrejda, Krzysztof; Iamsirithaworn, Sopon; Hinjoy, Soawapak; Suangtho, Paphanij; Suthachana, Suthanun; Clapham, Hannah E.; Salje, Henrik; Cummings, Derek A. T.; Lessler, Justin

    2016-01-01

    Epidemics of communicable diseases place a huge burden on public health infrastructures across the world. Producing accurate and actionable forecasts of infectious disease incidence at short and long time scales will improve public health response to outbreaks. However, scientists and public health officials face many obstacles in trying to create such real-time forecasts of infectious disease incidence. Dengue is a mosquito-borne virus that annually infects over 400 million people worldwide. We developed a real-time forecasting model for dengue hemorrhagic fever in the 77 provinces of Thailand. We created a practical computational infrastructure that generated multi-step predictions of dengue incidence in Thai provinces every two weeks throughout 2014. These predictions show mixed performance across provinces, out-performing seasonal baseline models in over half of provinces at a 1.5 month horizon. Additionally, to assess the degree to which delays in case reporting make long-range prediction a challenging task, we compared the performance of our real-time predictions with predictions made with fully reported data. This paper provides valuable lessons for the implementation of real-time predictions in the context of public health decision making. PMID:27304062

  10. Challenges in Real-Time Prediction of Infectious Disease: A Case Study of Dengue in Thailand.

    PubMed

    Reich, Nicholas G; Lauer, Stephen A; Sakrejda, Krzysztof; Iamsirithaworn, Sopon; Hinjoy, Soawapak; Suangtho, Paphanij; Suthachana, Suthanun; Clapham, Hannah E; Salje, Henrik; Cummings, Derek A T; Lessler, Justin

    2016-06-01

    Epidemics of communicable diseases place a huge burden on public health infrastructures across the world. Producing accurate and actionable forecasts of infectious disease incidence at short and long time scales will improve public health response to outbreaks. However, scientists and public health officials face many obstacles in trying to create such real-time forecasts of infectious disease incidence. Dengue is a mosquito-borne virus that annually infects over 400 million people worldwide. We developed a real-time forecasting model for dengue hemorrhagic fever in the 77 provinces of Thailand. We created a practical computational infrastructure that generated multi-step predictions of dengue incidence in Thai provinces every two weeks throughout 2014. These predictions show mixed performance across provinces, out-performing seasonal baseline models in over half of provinces at a 1.5 month horizon. Additionally, to assess the degree to which delays in case reporting make long-range prediction a challenging task, we compared the performance of our real-time predictions with predictions made with fully reported data. This paper provides valuable lessons for the implementation of real-time predictions in the context of public health decision making.

  11. Lift-Off: Using Reference Imagery and Freehand Sketching to Create 3D Models in VR.

    PubMed

    Jackson, Bret; Keefe, Daniel F

    2016-04-01

    Three-dimensional modeling has long been regarded as an ideal application for virtual reality (VR), but current VR-based 3D modeling tools suffer from two problems that limit creativity and applicability: (1) the lack of control for freehand modeling, and (2) the difficulty of starting from scratch. To address these challenges, we present Lift-Off, an immersive 3D interface for creating complex models with a controlled, handcrafted style. Artists start outside of VR with 2D sketches, which are then imported and positioned in VR. Then, using a VR interface built on top of image processing algorithms, 2D curves within the sketches are selected interactively and "lifted" into space to create a 3D scaffolding for the model. Finally, artists sweep surfaces along these curves to create 3D models. Evaluations are presented for both long-term users and for novices who each created a 3D sailboat model from the same starting sketch. Qualitative results are positive, with the visual style of the resulting models of animals and other organic subjects as well as architectural models matching what is possible with traditional fine art media. In addition, quantitative data from logging features built into the software are used to characterize typical tool use and suggest areas for further refinement of the interface.

  12. Implementing Multisector Nutrition Programs in Ethiopia and Nepal: Challenges and Opportunities From a Stakeholder Perspective.

    PubMed

    Kennedy, Eileen; Fekadu, Habtamu; Ghosh, Shibani; Baral, Kedar; Davis, Dale; Sapkota, Diplav; Webb, Patrick

    2016-12-01

    Effective governance is essential for effective nutrition program implementation. There are additional challenges in launching multisector plans to enhance nutritional status. The present study compares the challenges and opportunities in Ethiopia and Nepal in designing and implementing a multisector plan for nutrition. A semi-quantitative questionnaire with open-ended questions was used to solicit information from senior national-level policy officials and other key stakeholders. The nature of the major nutrition problems in each country was similar; these include malnutrition (particularly stunting), food insecurity, and micronutrient malnutrition. The main challenges identified included the need for more specificity in the roles of agencies/individuals in program implementation, more effective mechanisms for linking national to subnational officials, methods for creating awareness of the plans, and a dedicated line item in the budgets of each agency. The level of enthusiasm was high in both countries. Respondents in both countries highlighted the need to identify a "champion" at the highest level who would keep the momentum for the respective plans alive. © The Author(s) 2016.

  13. Current Challenges in Commercially Producing Biofuels from Lignocellulosic Biomass

    PubMed Central

    Balan, Venkatesh

    2014-01-01

    Biofuels that are produced from biobased materials are a good alternative to petroleum based fuels. They offer several benefits to society and the environment. Producing second generation biofuels is even more challenging than producing first generation biofuels due the complexity of the biomass and issues related to producing, harvesting, and transporting less dense biomass to centralized biorefineries. In addition to this logistic challenge, other challenges with respect to processing steps in converting biomass to liquid transportation fuel like pretreatment, hydrolysis, microbial fermentation, and fuel separation still exist and are discussed in this review. The possible coproducts that could be produced in the biorefinery and their importance to reduce the processing cost of biofuel are discussed. About $1 billion was spent in the year 2012 by the government agencies in US to meet the mandate to replace 30% existing liquid transportation fuels by 2022 which is 36 billion gallons/year. Other countries in the world have set their own targets to replace petroleum fuel by biofuels. Because of the challenges listed in this review and lack of government policies to create the demand for biofuels, it may take more time for the lignocellulosic biofuels to hit the market place than previously projected. PMID:25937989

  14. Implementing Innovation: The Creation of an iUnit and the Role of Nursing.

    PubMed

    Tiase, Victoria L; Ventura, Rosemary; Sorbello, Daniel; Robinson, Kenya

    2016-01-01

    NewYork-Presbyterian Hospital took on the challenge of thinking about innovation differently with the implementation of an innovation unit or iUnit to create the patient care unit of the future. Goals were to understand more about the innovation process and to test new service models, technology platforms, devices, and deployment models. Key findings from the focus groups included the need for additional training and technical support. In general, the initiative was felt to improve overall communication and represents a starting point for further innovation programs.

  15. Machine‐Assisted Organic Synthesis

    PubMed Central

    Fitzpatrick, Daniel E.; Myers, Rebecca M.; Battilocchio, Claudio; Ingham, Richard. J.

    2015-01-01

    Abstract In this Review we describe how the advent of machines is impacting on organic synthesis programs, with particular emphasis on the practical issues associated with the design of chemical reactors. In the rapidly changing, multivariant environment of the research laboratory, equipment needs to be modular to accommodate high and low temperatures and pressures, enzymes, multiphase systems, slurries, gases, and organometallic compounds. Additional technologies have been developed to facilitate more specialized reaction techniques such as electrochemical and photochemical methods. All of these areas create both opportunities and challenges during adoption as enabling technologies. PMID:26193360

  16. Total knee arthroplasty in a patient with diastrophic dwarfism.

    PubMed

    Crowley, Robin L; Haas, Richard E

    2010-10-01

    Diastrophic dwarfism is an autosomal recessive disease that predominantly occurs in the Finnish population (1 in 33,000) but has been known to occur worldwide. Affected patients present with multiple cartilaginous anomalies and early degeneration of weight-bearing joints. Once past infancy, life expectancy is favorable and patients may undergo multiple surgical procedures throughout their lifetime to repair .or replace affected joints. The characteristic short trunk of these patients in addition to scoliosis, cervical kyphosis, and involvement of articular cartilages can create unique ventilation and airway challenges for anesthesia providers involved in their care.

  17. Community-based water-quality monitoring in the Yukon River Basin and the Kuskokwim Watershed

    USGS Publications Warehouse

    Herman-Mercer, Nicole M.

    2013-01-01

    The unique partnership between the USGS and the YRITWC provides mutual benefits by fostering outreach efforts that have been essential for community empowerment and by generating scientific data for prohibitively large and remote regions that would be challenging for USGS scientists to sample as robustly alone. The addition of a new partnership with the KRWC to create a community-based monitoring program will only increase these benefits by growing the spatial extent of data collection and empowering more people to take charge of important science in their own backyard.

  18. Creating a Transformational Learning Experience: Immersing Students in an Intensive Interdisciplinary Learning Environment

    ERIC Educational Resources Information Center

    White, Shelley K.; Nitkin, Mindell Reiss

    2014-01-01

    The Simmons World Challenge is a unique, interdisciplinary program recently developed at Simmons College. It immerses students in an intensive winter-session course that challenges them to tackle a pressing social issue, such as poverty or hunger, and create actionable solutions to the problem. The program was conceived and designed to harness the…

  19. Physics. Creating and probing electron whispering-gallery modes in graphene.

    PubMed

    Zhao, Yue; Wyrick, Jonathan; Natterer, Fabian D; Rodriguez-Nieva, Joaquin F; Lewandowski, Cyprian; Watanabe, Kenji; Taniguchi, Takashi; Levitov, Leonid S; Zhitenev, Nikolai B; Stroscio, Joseph A

    2015-05-08

    The design of high-finesse resonant cavities for electronic waves faces challenges due to short electron coherence lengths in solids. Complementing previous approaches to confine electronic waves by carefully positioned adatoms at clean metallic surfaces, we demonstrate an approach inspired by the peculiar acoustic phenomena in whispering galleries. Taking advantage of graphene's gate-tunable light-like carriers, we create whispering-gallery mode (WGM) resonators defined by circular pn junctions, induced by a scanning tunneling probe. We can tune the resonator size and the carrier concentration under the probe in a back-gated graphene device over a wide range. The WGM-type confinement and associated resonances are a new addition to the quantum electron-optics toolbox, paving the way to develop electronic lenses and resonators. Copyright © 2015, American Association for the Advancement of Science.

  20. [Development of an ophthalmological clinical information system for inpatient eye clinics].

    PubMed

    Kortüm, K U; Müller, M; Babenko, A; Kampik, A; Kreutzer, T C

    2015-12-01

    In times of increased digitalization in healthcare, departments of ophthalmology are faced with the challenge of introducing electronic clinical health records (EHR); however, specialized software for ophthalmology is not available with most major EHR sytems. The aim of this project was to create specific ophthalmological user interfaces for large inpatient eye care providers within a hospitalwide EHR. Additionally the integration of ophthalmic imaging systems, scheduling and surgical documentation should be achieved. The existing EHR i.s.h.med (Siemens, Germany) was modified using advanced business application programming (ABAP) language to create specific ophthalmological user interfaces for reproduction and moreover optimization of the clinical workflow. A user interface for documentation of ambulatory patients with eight tabs was designed. From June 2013 to October 2014 a total of 61,551 patient contact details were documented. For surgical documentation a separate user interface was set up. Digital clinical orders for documentation of registration and scheduling of operations user interfaces were also set up. A direct integration of ophthalmic imaging modalities could be established. An ophthalmologist-orientated EHR for outpatient and surgical documentation for inpatient clinics was created and successfully implemented. By incorporation of imaging procedures the foundation of future smart/big data analyses was created.

  1. Evaluation of a new mobile system for protecting immune-suppressed patients against airborne contamination.

    PubMed

    Poirot, Jean-Louis; Gangneux, Jean-Pierre; Fischer, Alain; Malbernard, Mireille; Challier, Svetlana; Laudinet, Nicolas; Bergeron, Vance

    2007-09-01

    Invasive aspergillosis is one of the most lethal airborne dangers for immune-suppressed subjects. Providing patient protection from such airborne threats requires costly and high-maintenance facilities. We herein evaluate a new self-contained mobile unit as an alternative for creating a patient protective environment. Airborne contamination levels were monitored for different simulated scenarios and under actual clinical conditions. Functional tests were used to challenge the unit under adverse conditions, and a preliminary clinical study with patients and staff present was performed at 2 different French hospitals. Functional tests demonstrated that the unit can rapidly decontaminate air in the protected zone created by the unit and in the surrounding room. In addition, the protected zone is not sensitive to large disturbances that occur in the room. The clinical study included 4 patients with 150 accumulated days of testing. The protected zone created by the unit systematically provided an environment with undetectable airborne fungal levels (ie, <1 CFU/m(3)) regardless of the levels in the room or corridor (P < .01). These tests show that the unit can be used to create a mobile protective environment for immune-suppressed patients in a standard hospital setting.

  2. Potential Space Applications for Body-Centric Wireless and E-Textile Antennas

    NASA Technical Reports Server (NTRS)

    Kennedy, Timothy F.; Fink, Patrick W.; Chu, Andrew W.; Studor, George F.

    2007-01-01

    Space environment benefits of body-centric wireless communications are numerous, particularly in the context of long duration Lunar and Martian outposts that are in planning stages at several space agencies around the world. Since crew time for such missions is a scarce commodity, seamless integration of body-centric wireless from various sources is paramount. Sources include traditional data, such as audio, video, tracking, and biotelemetry. Newer data sources include positioning, orientation, and status of handheld tools and devices, as well as management and status of on-body inventories. In addition to offering lighter weight and flexibility, performance benefits of e-textile antennas are anticipated due to advantageous use of the body s surface area. In creating e-textile antennas and RF devices, researchers are faced with the challenge of transferring conventional and novel designs to textiles. Lack of impedance control, limited conductivity, and the inability to automatically create intricate designs are examples of limitations frequently attributed to e-textiles. Reliable interfaces between e-textiles and conventional hardware also represent significant challenges. Addressing these limitations is critical to the continued development and acceptance of fabric-based circuits for body-centric wireless applications. Here we present several examples of e-textile antennas and RF devices, created using a NASA-developed process, that overcome several of these limitations. The design and performance of an equiangular spiral, miniaturized spiral-loaded slot antenna, and a hybrid coupler are considered, with the e-textile devices showing comparable performance to like designs using conventional materials.

  3. The Birth of Lepton Colliders in Italy and the United States

    NASA Astrophysics Data System (ADS)

    Paris, Elizabeth

    2003-04-01

    In 1960 the highest center-of-mass energies in particle physics were being achieved via proton synchrotrons utilizing stationary targets. However, efforts were already underway to challenge this hegemony. In addition to Soviet work in Novosibirsk, groups at Stanford University in California and at the Frascati National Laboratories near Rome each had begun original investigation towards one particular type of challenger: colliding beam storage rings. For the group in California, the accomplishment involved creating the potential for feasible experiments. The energetic advantages of the colliding beam configuration had long been accepted - together with its impossibility for realization. The builders of the Princeton-Stanford machine feel that creating usable beams and a reasonable reaction rate is what stood between this concept and its glorious future. For the European builders of AdA, however, the beauty emerges from recognizing the enormous potential inherent in electron-positron annihilations. At least as important for the rise of electron-positron colliders, though, is the role of both of these projects as cultural firsts -- as places where particular sets of physicists got their feet wet associating with beams and beam problems and with the many individuals who were addressing beam problems. The Princeton-Stanford Collider provided experience which its builders would use to move on, functioning as both a technological and political platform for creating what would eventually become SPEAR. For the Roman group, the pursuit of AdA encouraged investigation which applied equally well to their next machine, Adone.

  4. Flexible high-resolution display systems for the next generation of radiology reading rooms

    NASA Astrophysics Data System (ADS)

    Caban, Jesus J.; Wood, Bradford J.; Park, Adrian

    2007-03-01

    A flexible, scalable, high-resolution display system is presented to support the next generation of radiology reading rooms or interventional radiology suites. The project aims to create an environment for radiologists that will simultaneously facilitate image interpretation, analysis, and understanding while lowering visual and cognitive stress. Displays currently in use present radiologists with technical challenges to exploring complex datasets that we seek to address. These include resolution and brightness, display and ambient lighting differences, and degrees of complexity in addition to side-by-side comparison of time-variant and 2D/3D images. We address these issues through a scalable projector-based system that uses our custom-designed geometrical and photometrical calibration process to create a seamless, bright, high-resolution display environment that can reduce the visual fatigue commonly experienced by radiologists. The system we have designed uses an array of casually aligned projectors to cooperatively increase overall resolution and brightness. Images from a set of projectors in their narrowest zoom are combined at a shared projection surface, thus increasing the global "pixels per inch" (PPI) of the display environment. Two primary challenges - geometric calibration and photometric calibration - remained to be resolved before our high-resolution display system could be used in a radiology reading room or procedure suite. In this paper we present a method that accomplishes those calibrations and creates a flexible high-resolution display environment that appears seamless, sharp, and uniform across different devices.

  5. MO-DE-BRA-04: The CREATE Medical Physics Research Training Network: Training of New Generation Innovators

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Seuntjens, J; Collins, L; Devic, S

    Purpose: Over the past century, physicists have played a major role in transforming scientific discovery into everyday clinical applications. However, with the increasingly stringent requirements to regulate medical physics as a health profession, the role of physicists as scientists and innovators has become at serious risk of erosion. These challenges trigger the need for a new, revolutionized training program at the graduate level that respects scientific rigor, attention for medical physics-relevant developments in basic sciences, innovation and entrepreneurship. Methods: A grant proposal was funded by the Collaborative REsearch and Training Experience program (CREATE) of the Natural Sciences and Engineering Researchmore » Council (NSERC) of Canada. This enabled the creation of the Medical Physics Research Training Network (MPRTN) around two CAMPEP-accredited medical physics programs. Members of the network consist of medical device companies, government (research and regulatory) and academia. The MPRTN/CREATE program proposes a curriculum with three main themes: (1) radiation physics, (2) imaging & image processing and (3) radiation response, outcomes and modeling. Results: The MPRTN was created mid 2013 (mprtn.com) and features (1) four new basic Ph.D. courses; (2) industry participation in research projects; (3) formal job-readiness training with involvement of guest faculty from academia, government and industry. MPRTN activities since 2013 include 22 conferences; 7 workshops and 4 exchange travels. Three patents were filed or issued, nine awards/best papers were won. Fifteen journal publications were accepted/published, 102 conference abstracts. There are now 13 industry partners. Conclusion: A medical physics research training network has been set up with the goal to harness graduate student’s job-readiness for industry, government and academia in addition to the conventional clinical role. Two years after inception, significant successes have been booked, but the true challenge will be to demonstrate that with this training philosophy CREATE scholars gain access to a much broader job market. Supported by the Natural Sciences and Engineering Research Council (NSERC) Canada.« less

  6. Community Cloud Computing

    NASA Astrophysics Data System (ADS)

    Marinos, Alexandros; Briscoe, Gerard

    Cloud Computing is rising fast, with its data centres growing at an unprecedented rate. However, this has come with concerns over privacy, efficiency at the expense of resilience, and environmental sustainability, because of the dependence on Cloud vendors such as Google, Amazon and Microsoft. Our response is an alternative model for the Cloud conceptualisation, providing a paradigm for Clouds in the community, utilising networked personal computers for liberation from the centralised vendor model. Community Cloud Computing (C3) offers an alternative architecture, created by combing the Cloud with paradigms from Grid Computing, principles from Digital Ecosystems, and sustainability from Green Computing, while remaining true to the original vision of the Internet. It is more technically challenging than Cloud Computing, having to deal with distributed computing issues, including heterogeneous nodes, varying quality of service, and additional security constraints. However, these are not insurmountable challenges, and with the need to retain control over our digital lives and the potential environmental consequences, it is a challenge we must pursue.

  7. Aerodynamic challenges of ALT

    NASA Technical Reports Server (NTRS)

    Hooks, I.; Homan, D.; Romere, P. O.

    1985-01-01

    The approach and landing test (ALT) of the Space Shuttle Orbiter presented a number of unique challenges in the area of aerodynamics. The purpose of the ALT program was both to confirm the use of the Boeing 747 as a transport vehicle for ferrying the Orbiter across the country and to demonstrate the flight characteristics of the Orbiter in its approach and landing phase. Concerns for structural fatigue and performance dictated a tailcone be attached to the Orbiter for ferry and for the initial landing tests. The Orbiter with a tailcone attached presented additional challenges to the normal aft sting concept of wind tunnel testing. The landing tests required that the Orbiter be separated from the 747 at approximately 20,000 feet using aerodynamic forces to fly the vehicles apart. The concept required a complex test program to determine the relative effects of the two vehicles on each other. Also of concern, and tested, was the vortex wake created by the 747 and the means for the Orbiter to avoid it following separation.

  8. IT Tools for Teachers and Scientists, Created by Undergraduate Researchers

    NASA Astrophysics Data System (ADS)

    Millar, A. Z.; Perry, S.

    2007-12-01

    Interns in the Southern California Earthquake Center/Undergraduate Studies in Earthquake Information Technology (SCEC/UseIT) program conduct computer science research for the benefit of earthquake scientists and have created products in growing use within the SCEC education and research communities. SCEC/UseIT comprises some twenty undergraduates who combine their varied talents and academic backgrounds to achieve a Grand Challenge that is formulated around needs of SCEC scientists and educators and that reflects the value SCEC places on the integration of computer science and the geosciences. In meeting the challenge, students learn to work on multidisciplinary teams and to tackle complex problems with no guaranteed solutions. Meantime, their efforts bring fresh perspectives and insight to the professionals with whom they collaborate, and consistently produces innovative, useful tools for research and education. The 2007 Grand Challenge was to design and prototype serious games to communicate important earthquake science concepts. Interns broke themselves into four game teams, the Educational Game, the Training Game, the Mitigation Game and the Decision-Making Game, and created four diverse games with topics from elementary plate tectonics to earthquake risk mitigation, with intended players ranging from elementary students to city planners. The games were designed to be versatile, to accommodate variation in the knowledge base of the player; and extensible, to accommodate future additions. The games are played on a web browser or from within SCEC-VDO (Virtual Display of Objects). SCEC-VDO, also engineered by UseIT interns, is a 4D, interactive, visualization software that enables integration and exploration of datasets and models such as faults, earthquake hypocenters and ruptures, digital elevation models, satellite imagery, global isochrons, and earthquake prediction schemes. SCEC-VDO enables the user to create animated movies during a session, and is now part of a multi-media, general education curriculum at University of Southern California. Throughout this meeting, at the SCEC booth, UseIT interns will be demonstrating both the serious games and SCEC-VDO. SCEC/UseIT is a National Science Foundation Research Experience for Undergraduates site.

  9. The Impact That Change in the Registration Calendar Has on Student Outcomes, and the Reduction of Late Registration

    ERIC Educational Resources Information Center

    Fobbs, Timothy J.

    2015-01-01

    Students who register for classes late have always been a challenge for community colleges. The student who registers late creates a burden on the enrollment staff, and they create academic achievement challenges for themselves as well. Late class registration has been linked to lower overall GPA's, and to overall lower academic performance. This…

  10. A Teaching Conference of One's Own: Inviting Faculty into the Scholarly Work of Teaching

    ERIC Educational Resources Information Center

    Sievers, Julie

    2015-01-01

    This essay examines the value of creating a peer-reviewed conference on teaching at one's own campus. A conference created by faculty and for faculty is an effective way to address several challenges faced by many teaching centers, especially the challenge of involving a wide range of faculty in scholarly approaches to teaching. I cite experience…

  11. Effects of Full and Quasi-Participatory Learning Strategies on Nigerian Senior Secondary Students' Environmental Knowledge: Implications for Classroom Practice

    ERIC Educational Resources Information Center

    Ajiboye, Josiah O.; Ajitoni, S. O.

    2008-01-01

    Environmental education is considered an appropriate intervention for creating awareness of, and an understanding of the challenges of environmental degradation. The introduction of EE into the Nigerian school curricular creates a challenge of how to teach it. A majority of the teachers still employ the old, traditional "chalk and talk"…

  12. Patient-specific in vitro models for hemodynamic analysis of congenital heart disease - Additive manufacturing approach.

    PubMed

    Medero, Rafael; García-Rodríguez, Sylvana; François, Christopher J; Roldán-Alzate, Alejandro

    2017-03-21

    Non-invasive hemodynamic assessment of total cavopulmonary connection (TCPC) is challenging due to the complex anatomy. Additive manufacturing (AM) is a suitable alternative for creating patient-specific in vitro models for flow measurements using four-dimensional (4D) Flow MRI. These in vitro systems have the potential to serve as validation for computational fluid dynamics (CFD), simulating different physiological conditions. This study investigated three different AM technologies, stereolithography (SLA), selective laser sintering (SLS) and fused deposition modeling (FDM), to determine differences in hemodynamics when measuring flow using 4D Flow MRI. The models were created using patient-specific MRI data from an extracardiac TCPC. These models were connected to a perfusion pump circulating water at three different flow rates. Data was processed for visualization and quantification of velocity, flow distribution, vorticity and kinetic energy. These results were compared between each model. In addition, the flow distribution obtained in vitro was compared to in vivo. The results showed significant difference in velocities measured at the outlets of the models that required internal support material when printing. Furthermore, an ultrasound flow sensor was used to validate flow measurements at the inlets and outlets of the in vitro models. These results were highly correlated to those measured with 4D Flow MRI. This study showed that commercially available AM technologies can be used to create patient-specific vascular models for in vitro hemodynamic studies at reasonable costs. However, technologies that do not require internal supports during manufacturing allow smoother internal surfaces, which makes them better suited for flow analyses. Copyright © 2017 Elsevier Ltd. All rights reserved.

  13. Grand Challenges in Clinical Decision Support v10

    PubMed Central

    Sittig, Dean F.; Wright, Adam; Osheroff, Jerome A.; Middleton, Blackford; Teich, Jonathan M.; Ash, Joan S.; Campbell, Emily; Bates, David W.

    2008-01-01

    There is a pressing need for high-quality, effective means of designing, developing, presenting, implementing, evaluating, and maintaining all types of clinical decision support capabilities for clinicians, patients and consumers. Using an iterative, consensus-building process we identified a rank-ordered list of the top 10 grand challenges in clinical decision support. This list was created to educate and inspire researchers, developers, funders, and policy-makers. The list of challenges in order of importance that they be solved if patients and organizations are to begin realizing the fullest benefits possible of these systems consists of: Improve the human-computer interface; Disseminate best practices in CDS design, development, and implementation; Summarize patient-level information; Prioritize and filter recommendations to the user; Create an architecture for sharing executable CDS modules and services; Combine recommendations for patients with co-morbidities; Prioritize CDS content development and implementation; Create internet-accessible clinical decision support repositories; Use freetext information to drive clinical decision support; Mine large clinical databases to create new CDS. Identification of solutions to these challenges is critical if clinical decision support is to achieve its potential and improve the quality, safety and efficiency of healthcare. PMID:18029232

  14. Post-Closure Challenges of U.S. Department of Energy Sites in Desert Environments of the Southwestern United States - 12095

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gil, April; Steckley, Deborah; Gauthier, Cassie

    2012-07-01

    U.S. Department of Energy (DOE) sites located in harsh desert environments of the Four Corners region of the southwestern United States require diligence and continual maintenance to ensure the remediation systems function as designed to protect human health and the environment. The geology and climate of this area create issues that are unique to these sites. Geologic formations contain naturally occurring constituents that are often the same as the residual contaminants remaining from historical milling activities at the sites. Although annual precipitation is low, when precipitation events occur they can be of extreme intensity, resulting in erosion and flooding thatmore » can quickly destroy infrastructure and rapidly change site conditions. Winds can cause sand storms and sand mounding that effect site features. These challenging environmental conditions, along with the remote locations of the sites, require active management beyond what was originally envisioned for uranium disposal sites to address concerns in a safe and cost-effective manner. The unique environment of the Four Corners region creates many challenges to the LTSM of LM sites in southwestern United States. The remediation efforts and approaches to infrastructure have to be specifically structured to work in this environment. Often, the systems and structures have to be modified based on lessons learned on how to best adapt to these difficult conditions and remote locations. These sites require continual maintenance and additional efforts compared to many other LM sites. (authors)« less

  15. Toward a Digital Thread and Data Package for Metals-Additive Manufacturing.

    PubMed

    Kim, D B; Witherell, P; Lu, Y; Feng, S

    2017-01-01

    Additive manufacturing (AM) has been envisioned by many as a driving factor of the next industrial revolution. Potential benefits of AM adoption include the production of low-volume, customized, complicated parts/products, supply chain efficiencies, shortened time-to-market, and environmental sustainability. Work remains, however, for AM to reach the status of a full production-ready technology. Whereas the ability to create unique 3D geometries has been generally proven, production challenges remain, including lack of (1) data manageability through information management systems, (2) traceability to promote product producibility, process repeatability, and part-to-part reproducibility, and (3) accountability through mature certification and qualification methodologies. To address these challenges in part, this paper discusses the building of data models to support the development of validation and conformance methodologies in AM. We present an AM information map that leverages informatics to facilitate part producibility, process repeatability, and part-to-part reproducibility in an AM process. We present three separate case studies to demonstrate the importance of establishing baseline data structures and part provenance through an AM digital thread.

  16. Toward a Digital Thread and Data Package for Metals-Additive Manufacturing

    PubMed Central

    Kim, D. B.; Witherell, P.; Lu, Y.; Feng, S.

    2017-01-01

    Additive manufacturing (AM) has been envisioned by many as a driving factor of the next industrial revolution. Potential benefits of AM adoption include the production of low-volume, customized, complicated parts/products, supply chain efficiencies, shortened time-to-market, and environmental sustainability. Work remains, however, for AM to reach the status of a full production-ready technology. Whereas the ability to create unique 3D geometries has been generally proven, production challenges remain, including lack of (1) data manageability through information management systems, (2) traceability to promote product producibility, process repeatability, and part-to-part reproducibility, and (3) accountability through mature certification and qualification methodologies. To address these challenges in part, this paper discusses the building of data models to support the development of validation and conformance methodologies in AM. We present an AM information map that leverages informatics to facilitate part producibility, process repeatability, and part-to-part reproducibility in an AM process. We present three separate case studies to demonstrate the importance of establishing baseline data structures and part provenance through an AM digital thread. PMID:28691115

  17. Biobehavioral Factors That Shape Nutrition in Low-Income Populations: A Narrative Review.

    PubMed

    Laraia, Barbara A; Leak, Tashara M; Tester, June M; Leung, Cindy W

    2017-02-01

    Although evidence exists for an association between income level and diet quality, a causal relationship has not been established. A number of studies found that the price of nutritious food and the time cost to prepare foods are economically driven reasons for this relationship. However, in addition to economic constraints, low-income individuals and families face a number of additional challenges linked with food choice, eating behaviors, and diet-related chronic conditions that contribute to diet quality and health. Low-income individuals have a higher burden of employment-, food-, and housing-related insecurity that threaten the livelihood of their household. Poverty and exposure to these insecurities are hypothesized to activate biobehavioral and psychological mechanisms-endocrine, immune, and neurologic systems-that influence food choice and consumption. Examples of biobehavioral and psychological factors that influence diet are stress, poor sleep, and diminished cognitive capacity. High levels of stress, poor sleep, and cognitive overload compound the challenges of economic constraints, creating a mentality of scarcity that leads to poor diet quality. Copyright © 2016 American Journal of Preventive Medicine. Published by Elsevier Inc. All rights reserved.

  18. Creating a pandemic of health: What is the role of digital technologies?

    PubMed

    Jadad, Alejandro R

    2016-11-01

    Imagine a world in which every human being is healthy until the last breath. Thanks to the fast penetration of digital technologies in every region of the planet, this seemingly utopian scenario is not only feasible but also potentially viable. Now that digital technologies have provided almost full interconnectivity among all humans, they should be used to meet key challenges to ensure that health is created and that it spreads to reach every person on earth. The objective of this article is to describe and trigger a serious discussion of such challenges, which include: adopting a new concept of health; positioning self-rated health as the main outcome of the system; creating a health-oriented model to guide service provision; facilitating the identification, scaling up, and sustaining of innovations that can create and spread health; promoting a culture of health promotion; and encouraging the emergence of Precision Health. Once these challenges are met, and health becomes pandemic, public health would have fulfilled its vision, a healthy life for all, at last.

  19. Current Ketamine Practice: Results of the 2016 American Society of Pain Management Nursing Survey on Ketamine.

    PubMed

    Klaess, Cynthia C; Jungquist, Carla R

    2018-06-01

    Ketamine is increasingly utilized for a variety of pain management challenges. Audience comments from a ketamine presentation at the 2015 American Society of Pain Management Nursing (ASPMN) Conference reflected wide variation in ketamine practices as well as barriers to use. The goal was to gain a greater understanding of ASPMN member practice patterns and barriers related to ketamine as adjunctive therapy for pain management. A questionnaire survey design was used. Respondents represented 35 states and 2 countries. The participants were 146 respondents from ASPMN membership (1,485 members). The survey was distributed by ASPMN on SurveyMonkey. Practice setting and ketamine administration practices were assessed with areas for comments. Results were reviewed using frequencies to describe responses and formatted into tables. Comments were individually reviewed and grouped into common themes. Administration of ketamine as an analgesic was reported by 63% of respondents. Continuous intravenous ketamine infusions were the most common route of administration (65%); however, wide variability in dosing and length of therapy was reported. A wide variety of practices and challenges related to ketamine utilization were noted. Numerous studies have indicated the analgesic benefits of ketamine in pain management. The lack of practice standardization has created challenges to its consistent use and outcome measurement. Additionally, the off-label use of ketamine for pain management creates its own unique challenges. However, given the current national climate with intense focus on pain management, interdisciplinary practitioners have an ideal opportunity to evaluate ketamine's use in a comprehensive approach to pain management. Copyright © 2018 American Society for Pain Management Nursing. Published by Elsevier Inc. All rights reserved.

  20. A 3D bioprinting exemplar of the consequences of the regulatory requirements on customized processes.

    PubMed

    Hourd, Paul; Medcalf, Nicholas; Segal, Joel; Williams, David J

    2015-01-01

    Computer-aided 3D printing approaches to the industrial production of customized 3D functional living constructs for restoration of tissue and organ function face significant regulatory challenges. Using the manufacture of a customized, 3D-bioprinted nasal implant as a well-informed but hypothetical exemplar, we examine how these products might be regulated. Existing EU and USA regulatory frameworks do not account for the differences between 3D printing and conventional manufacturing methods or the ability to create individual customized products using mechanized rather than craft approaches. Already subject to extensive regulatory control, issues related to control of the computer-aided design to manufacture process and the associated software system chain present additional scientific and regulatory challenges for manufacturers of these complex 3D-bioprinted advanced combination products.

  1. Additive Manufacturing: Unlocking the Evolution of Energy Materials

    PubMed Central

    Zhakeyev, Adilet; Wang, Panfeng; Shu, Wenmiao; Wang, Huizhi

    2017-01-01

    Abstract The global energy infrastructure is undergoing a drastic transformation towards renewable energy, posing huge challenges on the energy materials research, development and manufacturing. Additive manufacturing has shown its promise to change the way how future energy system can be designed and delivered. It offers capability in manufacturing complex 3D structures, with near‐complete design freedom and high sustainability due to minimal use of materials and toxic chemicals. Recent literatures have reported that additive manufacturing could unlock the evolution of energy materials and chemistries with unprecedented performance in the way that could never be achieved by conventional manufacturing techniques. This comprehensive review will fill the gap in communicating on recent breakthroughs in additive manufacturing for energy material and device applications. It will underpin the discoveries on what 3D functional energy structures can be created without design constraints, which bespoke energy materials could be additively manufactured with customised solutions, and how the additively manufactured devices could be integrated into energy systems. This review will also highlight emerging and important applications in energy additive manufacturing, including fuel cells, batteries, hydrogen, solar cell as well as carbon capture and storage. PMID:29051861

  2. Additive Manufacturing: Unlocking the Evolution of Energy Materials.

    PubMed

    Zhakeyev, Adilet; Wang, Panfeng; Zhang, Li; Shu, Wenmiao; Wang, Huizhi; Xuan, Jin

    2017-10-01

    The global energy infrastructure is undergoing a drastic transformation towards renewable energy, posing huge challenges on the energy materials research, development and manufacturing. Additive manufacturing has shown its promise to change the way how future energy system can be designed and delivered. It offers capability in manufacturing complex 3D structures, with near-complete design freedom and high sustainability due to minimal use of materials and toxic chemicals. Recent literatures have reported that additive manufacturing could unlock the evolution of energy materials and chemistries with unprecedented performance in the way that could never be achieved by conventional manufacturing techniques. This comprehensive review will fill the gap in communicating on recent breakthroughs in additive manufacturing for energy material and device applications. It will underpin the discoveries on what 3D functional energy structures can be created without design constraints, which bespoke energy materials could be additively manufactured with customised solutions, and how the additively manufactured devices could be integrated into energy systems. This review will also highlight emerging and important applications in energy additive manufacturing, including fuel cells, batteries, hydrogen, solar cell as well as carbon capture and storage.

  3. An overview of chemical additives present in plastics: Migration, release, fate and environmental impact during their use, disposal and recycling.

    PubMed

    Hahladakis, John N; Velis, Costas A; Weber, Roland; Iacovidou, Eleni; Purnell, Phil

    2018-02-15

    Over the last 60 years plastics production has increased manifold, owing to their inexpensive, multipurpose, durable and lightweight nature. These characteristics have raised the demand for plastic materials that will continue to grow over the coming years. However, with increased plastic materials production, comes increased plastic material wastage creating a number of challenges, as well as opportunities to the waste management industry. The present overview highlights the waste management and pollution challenges, emphasising on the various chemical substances (known as "additives") contained in all plastic products for enhancing polymer properties and prolonging their life. Despite how useful these additives are in the functionality of polymer products, their potential to contaminate soil, air, water and food is widely documented in literature and described herein. These additives can potentially migrate and undesirably lead to human exposure via e.g. food contact materials, such as packaging. They can, also, be released from plastics during the various recycling and recovery processes and from the products produced from recyclates. Thus, sound recycling has to be performed in such a way as to ensure that emission of substances of high concern and contamination of recycled products is avoided, ensuring environmental and human health protection, at all times. Crown Copyright © 2017. Published by Elsevier B.V. All rights reserved.

  4. Models and methods in delay discounting.

    PubMed

    Tesch, Aaron D; Sanfey, Alan G

    2008-04-01

    Delay discounting (DD) is a term typically used to describe the devaluation of rewards over time, and much research across a wide variety of domains has illustrated that people in general prefer a smaller reward delivered soon as opposed to a larger reward delivered at a later stage. Despite numerous attempts, a single unified model of DD that accounts for the varied pattern of results typically observed has been elusive. One of the difficulties in deriving a unified model is the presence of many framing and context effects, situations in which changing, apparently irrelevant, aspects of the choice scenarios lead to different selections. Additionally, different paradigms of DD research use quite different methodology, which poses challenges for a unified model. This chapter describes some of the difficulties in creating a single DD model and suggests some experiments that would help integrate different paradigms to create a clearer picture of DD.

  5. Current Efforts and Future Prospects in the Development of Live Mycobacteria as Vaccines

    PubMed Central

    Porcelli, Steven A.; Ng, Tony W.; Saavedra-Avila, Noemi A; Kennedy, Steven C.; Carreno, Leandro J.

    2016-01-01

    Summary The development of more effective vaccines against Mycobacterium tuberculosis (Mtb) remains a major goal in the effort to reduce the enormous global burden of disease caused by this pathogen. Whole-cell vaccines based on live mycobacteria with attenuated virulence represent an appealing approach, providing broad antigen exposure and intrinsic adjuvant properties to prime durable immune responses. However, designing vaccine strains with an optimal balance between attenuation and immunogenicity has proven to be extremely challenging. Recent basic and clinical research efforts have broadened our understanding of Mtb pathogenesis and created numerous new vaccine candidates that are designed to overcome different aspects of immune evasion by Mtb. In this review, we provide an overview of current efforts to create improved vaccines against tuberculosis based on modifications of live attenuated mycobacteria. In addition, we discuss the use of such vaccine strains as vectors for stimulating protective immunity against other infectious diseases and cancers. PMID:26366616

  6. Creation of digital contours that approach the characteristics of cartographic contours

    USGS Publications Warehouse

    Tyler, Dean J.; Greenlee, Susan K.

    2012-01-01

    The capability to easily create digital contours using commercial off-the-shelf (COTS) software has existed for decades. Out-of-the-box raw contours are suitable for many scientific applications without pre- or post-processing; however, cartographic applications typically require additional improvements. For example, raw contours generally require smoothing before placement on a map. Cartographic contours must also conform to certain spatial/logical rules; for example, contours may not cross waterbodies. The objective was to create contours that match as closely as possible the cartographic contours produced by manual methods on the 1:24,000-scale, 7.5-minute Topographic Map series. This report outlines the basic approach, describes a variety of problems that were encountered, and discusses solutions. Many of the challenges described herein were the result of imperfect input raster elevation data and the requirement to have the contours integrated with hydrographic features from the National Hydrography Dataset (NHD).

  7. Health insurance exchanges of past and present offer examples of features that could attract small-business customers.

    PubMed

    Gardiner, Terry

    2012-02-01

    The Affordable Care Act calls on states to create health insurance exchanges serving small businesses by 2014. These exchanges will allow small-business owners to pool their buying power, have more choices of health plans, and buy affordable health insurance. However, creating an exchange that appeals to small-business owners poses several challenges. Past and current exchanges provide valuable insights into the role exchanges can play, services they can offer, and design features that can make them successful. For example, states should allow insurance brokers to provide employers with advice and analysis regarding plans offered in the exchanges. Exchanges should also provide services to ease enrollment, such as a single application for all of the plans they offer, and make additional benefits, such as wellness programs, available on a stand-alone basis or within insurance plans.

  8. Creation of next generation U.S. Geological Survey topographic maps

    USGS Publications Warehouse

    Craun, Kari J.

    2010-01-01

    The U.S. Geological Survey (USGS) is 2 years into a 3-year cycle to create new digital topographic map products for the conterminous United States from data acquired and maintained as part of The National Map databases. These products are in the traditional, USGS topographic quadrangle, 7.5-minute (latitude and longitude) cell format. The 3-year cycle was conceived to follow the acquisition of National Aerial Imagery Program (NAIP) orthorectified imagery, a key layer in the new product. In fiscal year (FY) 2009 (ending September 30, 2009), the first year of the 3-year cycle, the USGS produced 13,200 products. These initial products of the “Digital MapBeta” series had limited feature content, including only the NAIP image, some roads, geographic names, and grid and collar information. The products were created in layered georegistered Portable Document Format (PDF) files, allowing users with freely available Adobe® Reader® software to view, print, and perform simple Geographic Information System-like functions. In FY 2010 (ending September 30, 2010), the USGS produced 20,380 products. These products of the “US Topo” series added hydrography (surface water features), contours, and some boundaries. In FY 2011 (ending September 30, 2011), the USGS will complete the initial coverage with US Topo products and will add additional feature content to the maps. The design, development, and production associated with the US Topo products provide management and technical challenges for the USGS and its public and private sector partners. One challenge is the acquisition and maintenance of nationally consistent base map data from multiple sources. Another is the use of these data to create a consistent, current series of cartographic products that can be used by the broad spectrum of traditional topographic map users. Although the USGS and its partners have overcome many of these challenges, many, such as establishing and funding a sustainable base data-maintenance program, remain to be resolved for the long term.

  9. Creating Inclusive School Environments: Recommendations for the Management of Neurobehavioural Comorbidities in Children with Epilepsy

    ERIC Educational Resources Information Center

    MacKinnon, Cheryl; Roberts, Jillian; Wylie, Jaimie

    2016-01-01

    The neurobehavioural comorbidities associated with childhood epilepsy present significant physical challenges (i.e., excessive fatigue, memory impairment, headaches, visual impairments), emotional challenges (i.e., depression, anxiety), behavioural challenges (i.e., inattentiveness, distractibility, aggression), and social challenges (i.e., peer…

  10. Case study: the introduction of stereoscopic games on the Sony PlayStation 3

    NASA Astrophysics Data System (ADS)

    Bickerstaff, Ian

    2012-03-01

    A free stereoscopic firmware update on Sony Computer Entertainment's PlayStation® 3 console provides the potential to increase enormously the popularity of stereoscopic 3D in the home. For this to succeed though, a large selection of content has to become available that exploits 3D in the best way possible. In addition to the existing challenges found in creating 3D movies and television programmes, the stereography must compensate for the dynamic and unpredictable environments found in games. Automatically, the software must map the depth range of the scene into the display's comfort zone, while minimising depth compression. This paper presents a range of techniques developed to solve this problem and the challenge of creating twice as many images as the 2D version without excessively compromising the frame rate or image quality. At the time of writing, over 80 stereoscopic PlayStation 3 games have been released and notable titles are used as examples to illustrate how the techniques have been adapted for different game genres. Since the firmware's introduction in 2010, the industry has matured with a large number of developers now producing increasingly sophisticated 3D content. New technologies such as viewer head tracking and head-mounted displays should increase the appeal of 3D in the home still further.

  11. Scaling the PuNDIT project for wide area deployments

    NASA Astrophysics Data System (ADS)

    McKee, Shawn; Batista, Jorge; Carcassi, Gabriele; Dovrolis, Constantine; Lee, Danny

    2017-10-01

    In today’s world of distributed scientific collaborations, there are many challenges to providing reliable inter-domain network infrastructure. Network operators use a combination of active monitoring and trouble tickets to detect problems, but these are often ineffective at identifying issues that impact wide-area network users. Additionally, these approaches do not scale to wide area inter-domain networks due to unavailability of data from all the domains along typical network paths. The Pythia Network Diagnostic InfrasTructure (PuNDIT) project aims to create a scalable infrastructure for automating the detection and localization of problems across these networks. The project goal is to gather and analyze metrics from existing perfSONAR monitoring infrastructures to identify the signatures of possible problems, locate affected network links, and report them to the user in an intuitive fashion. Simply put, PuNDIT seeks to convert complex network metrics into easily understood diagnoses in an automated manner. We present our progress in creating the PuNDIT system and our status in developing, testing and deploying PuNDIT. We report on the project progress to-date, describe the current implementation architecture and demonstrate some of the various user interfaces it will support. We close by discussing the remaining challenges and next steps and where we see the project going in the future.

  12. Using Human Induced Pluripotent Stem Cells to Model Skeletal Diseases.

    PubMed

    Barruet, Emilie; Hsiao, Edward C

    2016-01-01

    Musculoskeletal disorders affecting the bones and joints are major health problems among children and adults. Major challenges such as the genetic origins or poor diagnostics of severe skeletal disease hinder our understanding of human skeletal diseases. The recent advent of human induced pluripotent stem cells (human iPS cells) provides an unparalleled opportunity to create human-specific models of human skeletal diseases. iPS cells have the ability to self-renew, allowing us to obtain large amounts of starting material, and have the potential to differentiate into any cell types in the body. In addition, they can carry one or more mutations responsible for the disease of interest or be genetically corrected to create isogenic controls. Our work has focused on modeling rare musculoskeletal disorders including fibrodysplasia ossificans progressive (FOP), a congenital disease of increased heterotopic ossification. In this review, we will discuss our experiences and protocols differentiating human iPS cells toward the osteogenic lineage and their application to model skeletal diseases. A number of critical challenges and exciting new approaches are also discussed, which will allow the skeletal biology field to harness the potential of human iPS cells as a critical model system for understanding diseases of abnormal skeletal formation and bone regeneration.

  13. Internet marketing 401.

    PubMed

    Miller, Ryan J

    2010-11-01

    For facial plastic surgeons who are already realizing increased patient consultation requests from their online marketing efforts, the primary concern often becomes implementing additional tactics and strategies that can keep their online marketing fresh, relevant, and effective. This article creates a framework for evaluating advanced online marketing opportunities by analyzing each opportunity according to the variables of possible return, average cost to implement, probability of success, and implementation time. Within this framework, 11 distinct tactics are discussed, with special emphasis on the most common marketing needs and challenges of facial plastic surgery practices. Copyright © 2010 Elsevier Inc. All rights reserved.

  14. The meaning of higher education for people diagnosed with a mental illness: four students share their experiences.

    PubMed

    Knis-Matthews, Laurie; Bokara, Josephine; DeMeo, Lorena; Lepore, Nicole; Mavus, Lauren

    2007-01-01

    In this qualitative study, four participants diagnosed with a mental illness were interviewed to explore their experiences while attending a post-secondary school. Each participant described how education helped them to find a sense of purpose in their lives. Education is also described as a means of transition from the patient role to other roles such as student or worker. However, the symptoms and stigma associated with their mental illness has created additional challenges for them while in a school setting. Supportive professors and counselors were viewed as helpful in overcoming these barriers.

  15. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Moreno, Gilbert

    The objective for this project is to develop thermal management strategies to enable efficient and high-temperature wide-bandgap (WBG)-based power electronic systems (e.g., emerging inverter and DC-DC converter). Device- and system-level thermal analyses are conducted to determine the thermal limitations of current automotive power modules under elevated device temperature conditions. Additionally, novel cooling concepts and material selection will be evaluated to enable high-temperature silicon and WBG devices in power electronics components. WBG devices (silicon carbide [SiC], gallium nitride [GaN]) promise to increase efficiency, but will be driven as hard as possible. This creates challenges for thermal management and reliability.

  16. Current Challenges in Commercially Producing Biofuels from Lignocellulosic Biomass

    DOE PAGES

    Balan, Venkatesh

    2014-01-01

    Biofuels that are produced from biobased materials are a good alternative to petroleum based fuels. They offer several benefits to society and the environment. Producing second generation biofuels is even more challenging than producing first generation biofuels due the complexity of the biomass and issues related to producing, harvesting, and transporting less dense biomass to centralized biorefineries. In addition to this logistic challenge, other challenges with respect to processing steps in converting biomass to liquid transportation fuel like pretreatment, hydrolysis, microbial fermentation, and fuel separation still exist and are discussed in this review. The possible coproducts that could be producedmore » in the biorefinery and their importance to reduce the processing cost of biofuel are discussed. About $1 billion was spent in the year 2012 by the government agencies in US to meet the mandate to replace 30% existing liquid transportation fuels by 2022 which is 36 billion gallons/year. Other countries in the world have set their own targets to replace petroleum fuel by biofuels. Because of the challenges listed in this review and lack of government policies to create the demand for biofuels, it may take more time for the lignocellulosic biofuels to hit the market place than previously projected.« less

  17. Measuring Changes in the Economics of Medical Practice.

    PubMed

    Fleming, Christopher; Rich, Eugene; DesRoches, Catherine; Reschovsky, James; Kogan, Rachel

    2015-08-01

    For the latter third of the twentieth century, researchers have estimated production and cost functions for physician practices. Today, those attempting to measure the inputs and outputs of physician practice must account for many recent changes in models of care delivery. In this paper, we review practice inputs and outputs as typically described in research on the economics of medical practice, and consider the implications of the changing organization of medical practice and nature of physician work. This evolving environment has created conceptual challenges in what are the appropriate measures of output from physician work, as well as what inputs should be measured. Likewise, the increasing complexity of physician practice organizations has introduced challenges to finding the appropriate data sources for measuring these constructs. Both these conceptual and data challenges pose measurement issues that must be overcome to study the economics of modern medical practice. Despite these challenges, there are several promising initiatives involving data sharing at the organizational level that could provide a starting point for developing the needed new data sources and metrics for physician inputs and outputs. However, additional efforts will be required to establish data collection approaches and measurements applicable to smaller and single specialty practices. Overcoming these measurement and data challenges will be key to supporting policy-relevant research on the changing economics of medical practice.

  18. Adaptive eLearning modules for cytopathology education: A review and approach.

    PubMed

    Samulski, T Danielle; La, Teresa; Wu, Roseann I

    2016-11-01

    Clinical training imposes time and resource constraints on educators and learners, making it difficult to provide and absorb meaningful instruction. Additionally, innovative and personalized education has become an expectation of adult learners. Fortunately, the development of web-based educational tools provides a possible solution to these challenges. Within this review, we introduce the utility of adaptive eLearning platforms in pathology education. In addition to a review of the current literature, we provide the reader with a suggested approach for module creation, as well as a critical assessment of an available platform, based on our experience in creating adaptive eLearning modules for teaching basic concepts in gynecologic cytopathology. Diagn. Cytopathol. 2016;44:944-951. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  19. Polycrystalline Diamond Coating of Additively Manufactured Titanium for Biomedical Applications.

    PubMed

    Rifai, Aaqil; Tran, Nhiem; Lau, Desmond W; Elbourne, Aaron; Zhan, Hualin; Stacey, Alastair D; Mayes, Edwin L H; Sarker, Avik; Ivanova, Elena P; Crawford, Russell J; Tran, Phong A; Gibson, Brant C; Greentree, Andrew D; Pirogova, Elena; Fox, Kate

    2018-03-14

    Additive manufacturing using selective laser melted titanium (SLM-Ti) is used to create bespoke items across many diverse fields such as medicine, defense, and aerospace. Despite great progress in orthopedic implant applications, such as for "just in time" implants, significant challenges remain with regards to material osseointegration and the susceptibility to bacterial colonization on the implant. Here, we show that polycrystalline diamond coatings on these titanium samples can enhance biological scaffold interaction improving medical implant applicability. The highly conformable coating exhibited excellent bonding to the substrate. Relative to uncoated SLM-Ti, the diamond coated samples showed enhanced mammalian cell growth, enriched apatite deposition, and reduced microbial S. aureus activity. These results open new opportunities for novel coatings on SLM-Ti devices in general and especially show promise for improved biomedical implants.

  20. The real challenges: the orphan generation and employment creation.

    PubMed

    Whiteside, A

    2000-01-01

    A baby born to an HIV-positive mother has close to a 100% chance of being orphaned before reaching the age of 10. In South Africa, nearly 1 million children under the age of 15 are projected to lose their mothers by 2005 due to AIDS. These orphans are less likely to receive adequate parenting, education, and nutrition; others will seek to survive on the streets and thus will be more likely to face sexual abuse and exploitation. The long-term impact of HIV/AIDS on both the children and society will be severe. The orphans that AIDS is creating pose serious social, economic, political, and developmental challenges for South Africa. There are two options left for the government: 1) dramatically increasing welfare grants and staffing of welfare departments in order to care for the orphans; 2) find new imaginative measures of meeting the challenge. In addition, provision of employment for its population is another challenge the region is facing. Having the required resources and infrastructure, a potential intervention for South Africa would be training and employing a new cadre of workers to care for AIDS orphans. This type of response would also help build a civil society.

  1. Identifying challenges in project consultants engagement practices

    NASA Astrophysics Data System (ADS)

    Shariffuddin, Nadia Alina Amir; Abidin, Nazirah Zainul

    2017-10-01

    Construction projects, green or conventional, involve multi-faceted disciplines engaged with the goal of delivering products i.e. building, infrastructure etc. at the best quality within stipulated budgets. For green projects, additional attention is added for environmental quality. Due to the various responsibilities and liabilities involved as well as the complexity of the construction process itself, formal engagement of multi-disciplinary professionals i.e. project consultants is required in any construction project. Poor selection of project consultants will lead to a multitude of complications resulting in delay, cost escalation, conflicts and poor quality. This paper explores the challenges that occur during the engagement of project consultants in a green project. As the engagement decision involves developers and architects, these two groups of respondents with green project backgrounds were approached qualitatively using interview technique. The challenges identified are limited experience and knowledge, consultants' fee vs. quality, green complexity, conflicts of interest, clients' extended expectation and less demand in green projects. The construction shifts to green project demands engagement of project consultants with added skills. It is expected that through the identification of challenges, better management and administration can be created which would give impact to the overall process of engagement in green projects.

  2. Maximizing research study effectiveness in malaria elimination settings: a mixed methods study to capture the experiences of field-based staff.

    PubMed

    Canavati, Sara E; Quintero, Cesia E; Haller, Britt; Lek, Dysoley; Yok, Sovann; Richards, Jack S; Whittaker, Maxine Anne

    2017-09-11

    In a drug-resistant, malaria elimination setting like Western Cambodia, field research is essential for the development of novel anti-malarial regimens and the public health solutions necessary to monitor the spread of resistance and eliminate infection. Such field studies often face a variety of similar implementation challenges, but these are rarely captured in a systematic way or used to optimize future study designs that might overcome similar challenges. Field-based research staff often have extensive experience and can provide valuable insight regarding these issues, but their perspectives and experiences are rarely documented and seldom integrated into future research protocols. This mixed-methods analysis sought to gain an understanding of the daily challenges encountered by research field staff in the artemisinin-resistant, malaria elimination setting of Western Cambodia. In doing so, this study seeks to understand how the experiences and opinions of field staff can be captured, and used to inform future study designs. Twenty-two reports from six field-based malaria studies conducted in Western Cambodia were reviewed using content analysis to identify challenges to conducting the research. Informal Interviews, Focus Group Discussions and In-depth Interviews were also conducted among field research staff. Thematic analysis of the data was undertaken using Nvivo 9 ® software. Triangulation and critical case analysis was also used. There was a lack of formalized avenues through which field workers could report challenges experienced when conducting the malaria studies. Field research staff faced significant logistical barriers to participant recruitment and data collection, including a lack of available transportation to cover long distances, and the fact that mobile and migrant populations (MMPs) are usually excluded from studies because of challenges in follow-up. Cultural barriers to communication also hindered participant recruitment and created unexpected delays. Field staff often paid a physical, emotional and financial cost, going beyond their duty in order to keep the study running. Formal monthly reports filled out by field study staff could be a key tool for capturing field study staff experiences effectively, but require specific report fields to encourage staff to outline their challenges and to propose potential solutions. Forging strong bonds with communities and their leaders may improve communication, and decrease barriers to participant recruitment. Study designs that make it feasible for MMPs to participate should be pursued; in addition to increasing the potential participant pool, this will ensure that the most malaria-endemic demographic is taken into account in research studies. Overlaps between clinical care and research create ethical dilemmas for study staff, a fact that warrants careful consideration. Lessons learned from study field staff should be used to create a set of locally-relevant recommendations to inform future study designs.

  3. Challenges faced by former child soldiers in the aftermath of war in Uganda.

    PubMed

    Vindevogel, Sofie; De Schryver, Maarten; Broekaert, Eric; Derluyn, Ilse

    2013-06-01

    Warfare takes a profound toll of all layers of society, creating multiple and multilevel challenges that impinge on the psychosocial well-being of affected individuals. This study aims to assess the scope and salience of challenges confronting former child soldiers and at identifying additional challenges they face compared to non-recruited young people in war-affected northern Uganda. The study was carried out with a stratified random sample of northern Ugandan adolescents (n = 1,008), of whom a third had formerly been recruited (n = 330). The mixed-method comparison design consisted of a constrained free listing task to determine the challenges; a free sorting task to categorize them into clusters; and statistical analysis of their prevalence among formerly recruited youth and of how they compare with those of nonrecruited youth. Altogether, 237 challenges were identified and clustered into 15 categories, showing that formerly recruited participants mainly identified "emotional" and "training and skills"-related challenges. Compared with nonrecruited counterparts, they reported significantly more "emotional" and fewer "social and relational" challenges, with the exception of stigmatization. Overall, there was similarity between the challenges reported by both groups. The challenges confronting formerly recruited youths reach well beyond the effects of direct war exposure and emerge mainly from multiple influence spheres surrounding them. These challenges are largely shared in common with nonrecruited youths. This multidimensional and collective character of challenges calls for comprehensive psychosocial interventions through which healing the psychological wounds of war is complemented by mending the war-affected surroundings at all levels and in all life areas. Copyright © 2013 Society for Adolescent Health and Medicine. Published by Elsevier Inc. All rights reserved.

  4. Web Based Prognostics and 24/7 Monitoring

    NASA Technical Reports Server (NTRS)

    Strautkalns, Miryam; Robinson, Peter

    2013-01-01

    We created a general framework for analysts to store and view data in a way that removes the boundaries created by operating systems, programming languages, and proximity. With the advent of HTML5 and CSS3 with JavaScript the distribution of information is limited to only those who lack a browser. We created a framework based on the methodology: one server, one web based application. Additional benefits are increased opportunities for collaboration. Today the idea of a group in a single room is antiquated. Groups will communicate and collaborate with others from other universities, organizations, as well as other continents across times zones. There are many varieties of data gathering and condition-monitoring software available as well as companies who specialize in customizing software to individual applications. One single group will depend on multiple languages, environments, and computers to oversee recording and collaborating with one another in a single lab. The heterogeneous nature of the system creates challenges for seamless exchange of data and ideas between members. To address these limitations we designed a framework to allow users seamless accessibility to their data. Our framework was deployed using the data feed on the NASA Ames' planetary rover testbed. Our paper demonstrates the process and implementation we followed on the rover.

  5. Collaboration-Centred Cities through Urban Apps Based on Open and User-Generated Data

    PubMed Central

    Aguilera, Unai; López-de-Ipiña, Diego; Pérez, Jorge

    2016-01-01

    This paper describes the IES Cities platform conceived to streamline the development of urban apps that combine heterogeneous datasets provided by diverse entities, namely, government, citizens, sensor infrastructure and other information data sources. This work pursues the challenge of achieving effective citizen collaboration by empowering them to prosume urban data across time. Particularly, this paper focuses on the query mapper; a key component of the IES Cities platform devised to democratize the development of open data-based mobile urban apps. This component allows developers not only to use available data, but also to contribute to existing datasets with the execution of SQL sentences. In addition, the component allows developers to create ad hoc storages for their applications, publishable as new datasets accessible by other consumers. As multiple users could be contributing and using a dataset, our solution also provides a data level permission mechanism to control how the platform manages the access to its datasets. We have evaluated the advantages brought forward by IES Cities from the developers’ perspective by describing an exemplary urban app created on top of it. In addition, we include an evaluation of the main functionalities of the query mapper. PMID:27376300

  6. Collaboration-Centred Cities through Urban Apps Based on Open and User-Generated Data.

    PubMed

    Aguilera, Unai; López-de-Ipiña, Diego; Pérez, Jorge

    2016-07-01

    This paper describes the IES Cities platform conceived to streamline the development of urban apps that combine heterogeneous datasets provided by diverse entities, namely, government, citizens, sensor infrastructure and other information data sources. This work pursues the challenge of achieving effective citizen collaboration by empowering them to prosume urban data across time. Particularly, this paper focuses on the query mapper; a key component of the IES Cities platform devised to democratize the development of open data-based mobile urban apps. This component allows developers not only to use available data, but also to contribute to existing datasets with the execution of SQL sentences. In addition, the component allows developers to create ad hoc storages for their applications, publishable as new datasets accessible by other consumers. As multiple users could be contributing and using a dataset, our solution also provides a data level permission mechanism to control how the platform manages the access to its datasets. We have evaluated the advantages brought forward by IES Cities from the developers' perspective by describing an exemplary urban app created on top of it. In addition, we include an evaluation of the main functionalities of the query mapper.

  7. Challenges in Modeling and Measuring Learning Trajectories

    ERIC Educational Resources Information Center

    Confrey, Jere; Jones, R. Seth; Gianopulos, Garron

    2015-01-01

    Briggs and Peck make a compelling case for creating new, more intuitive measures of learning, based on creating vertical scales using learning trajectories (LT) in place of "domain sampling." We believe that the importance of creating measurement scales that coordinate recognizable landmarks in learning trajectories with interval scales…

  8. Challenges of Working in a Multicultural Environment.

    ERIC Educational Resources Information Center

    Howland, Joan S.

    2001-01-01

    Addresses challenges faced when working in a multicultural library setting and discusses the need for library administration to create supportive environments. Highlights include fluctuating power dynamics; merging diverse opinions and approaches; overcoming perceived lack of empathy; tokenism; accountability; and transforming challenges into…

  9. The challenge of giving written thesis feedback to nursing students.

    PubMed

    Tuvesson, Hanna; Borglin, Gunilla

    2014-11-01

    Providing effective written feedback on nursing student's assignments can be a challenging task for any assessor. Additionally, as the student groups tend to become larger, written feedback is likely to gain an overall more prominent position than verbal feedback. Lack of formal training or regular discussion in the teaching faculty about the skill set needed to provide written feedback could negatively affect the students' learning abilities. In this brief paper, we discuss written feedback practices, whilst using the Bachelor of Science in Nursing thesis as an example. Our aim is to highlight the importance of an informed understanding of the impact written feedback can have on students. Creating awareness about this can facilitate the development of more strategic and successful written feedback strategies. We end by offering examples of some relatively simple strategies for improving this practice. Copyright © 2014 Elsevier Ltd. All rights reserved.

  10. Fabrication technologies and sensing applications of graphene-based composite films: Advances and challenges.

    PubMed

    Yu, Xiaoqing; Zhang, Wensi; Zhang, Panpan; Su, Zhiqiang

    2017-03-15

    Graphene (G)-based composite materials have been widely explored for the sensing applications ascribing to their atom-thick two-dimensional conjugated structures, high conductivity, large specific surface areas and controlled modification. With the enormous advantages of film structure, G-based composite films (GCFs), prepared by combining G with different functional nanomaterials (noble metals, metal compounds, carbon materials, polymer materials, etc.), show unique optical, mechanical, electrical, chemical, and catalytic properties. Therefore, great quantities of sensors with high sensitivity, selectivity, and stability have been created in recent years. In this review, we focus on the recent advances in the fabrication technologies of GCFs and their specific sensing applications. In addition, the relationship between the properties of GCFs and sensing performance is concentrated on. Finally, the personal perspectives and key challenges of GCFs are mentioned in the hope to shed a light on their potential future research directions. Copyright © 2016 Elsevier B.V. All rights reserved.

  11. A Whale of a Tale: Creating Spacecraft Telemetry Data Analysis Products for the Deep Impact Mission

    NASA Technical Reports Server (NTRS)

    Sturdevant, Kathryn F.; Wright, Jesse J.; Lighty, Roger A.; Nakamura, Lori L.

    2006-01-01

    This paper describes some of the challenges and lessons learned from the Deep Impact (DI) Mission Ground Data System's (GDS) telemetry data processing and product generation tool, nicknamed 'Whale.' One of the challenges of any mission is to analyze testbed and operational telemetry data. Methods to retrieve this data to date have required spacecraft subsystem members to become experts in the use of a myriad of query and plot tools. As budgets shrink, and the GDS teams grow smaller, more of the burden to understand these tools falls on the users. The user base also varies from novice to expert, and requiring them to become GDS tool experts in addition to spacecraft domain experts is an undue burden. The "Whale" approach is to process all of the data for a given spacecraft test, and provide each subsystem with plots and data products 'automagically.'.

  12. Competency-based education in anesthesiology: history and challenges.

    PubMed

    Ebert, Thomas J; Fox, Chris A

    2014-01-01

    The Accreditation Council for Graduate Medical Education is transitioning to a competency-based system with milestones to measure progress and define success of residents. The confines of the time-based residency will be relaxed. Curriculum must be redesigned and assessments will need to be precise and in-depth. Core anesthesiology faculty will be identified and will be the "trained observers" of the residents' progress. There will be logistic challenges requiring creative management by program directors. There may be residents who achieve "expert" status earlier than the required 36 months of clinical anesthesia education, whereas others may struggle to achieve acceptable status and will require additional education time. Faculty must accept both extremes without judgment. Innovative new educational opportunities will need to be created for fast learners. Finally, it will be important that residents embrace this change. This will require programs to clearly define the specific aims and measurement endpoints for advancement and success.

  13. A theoretical framework for negotiating the path of emergency management multi-agency coordination.

    PubMed

    Curnin, Steven; Owen, Christine; Paton, Douglas; Brooks, Benjamin

    2015-03-01

    Multi-agency coordination represents a significant challenge in emergency management. The need for liaison officers working in strategic level emergency operations centres to play organizational boundary spanning roles within multi-agency coordination arrangements that are enacted in complex and dynamic emergency response scenarios creates significant research and practical challenges. The aim of the paper is to address a gap in the literature regarding the concept of multi-agency coordination from a human-environment interaction perspective. We present a theoretical framework for facilitating multi-agency coordination in emergency management that is grounded in human factors and ergonomics using the methodology of core-task analysis. As a result we believe the framework will enable liaison officers to cope more efficiently within the work domain. In addition, we provide suggestions for extending the theory of core-task analysis to an alternate high reliability environment. Copyright © 2014 Elsevier Ltd and The Ergonomics Society. All rights reserved.

  14. Open NASA Earth Exchange (OpenNEX): A Public-Private Partnership for Climate Change Research

    NASA Astrophysics Data System (ADS)

    Nemani, R. R.; Lee, T. J.; Michaelis, A.; Ganguly, S.; Votava, P.

    2014-12-01

    NASA Earth Exchange (NEX) is a data, computing and knowledge collaborative that houses satellite, climate and ancillary data where a community of researchers can come together to share modeling and analysis codes, scientific results, knowledge and expertise on a centralized platform with access to large supercomputing resources. As a part of broadening the community beyond NASA-funded researchers, NASA through an agreement with Amazon Inc. made available to the public a large collection of Climate and Earth Sciences satellite data. The data, available through the Open NASA Earth Exchange (OpenNEX) platform hosted by Amazon Web Services (AWS) public cloud, consists of large amounts of global land surface imaging, vegetation conditions, climate observations and climate projections. In addition to the data, users of OpenNEX platform can also watch lectures from leading experts, learn basic access and use of the available data sets. In order to advance White House initiatives such as Open Data, Big Data and Climate Data and the Climate Action Plan, NASA over the past six months conducted the OpenNEX Challenge. The two-part challenge was designed to engage the public in creating innovative ways to use NASA data and address climate change impacts on economic growth, health and livelihood. Our intention was that the challenges allow citizen scientists to realize the value of NASA data assets and offers NASA new ideas on how to share and use that data. The first "ideation" challenge, closed on July 31st attracted over 450 participants consisting of climate scientists, hobbyists, citizen scientists, IT experts and App developers. Winning ideas from the first challenge will be incorporated into the second "builder" challenge currently targeted to launch mid-August and close by mid-November. The winner(s) will be formally announced at AGU in December of 2014. We will share our experiences and lessons learned over the past year from OpenNEX, a public-private partnership for engaging and enabling a large community of citizen scientists to better understand global climate changes and in creating climate resilience.

  15. A Love for Learning: Motivation and the Gifted Child

    ERIC Educational Resources Information Center

    Whitney, Carol Strip; Hirsch, Gretchen

    2007-01-01

    Gifted children are susceptible to many de-motivating factors, which can lead to depression and academic underachievement. The authors present concepts and techniques to counteract those factors, allowing a child's motivation to skyrocket. Features the Four C's of Motivation: (1) Creating Challenge; (2) Creating Control; (3) Creating Commitment;…

  16. BrainIACS: a system for web-based medical image processing

    NASA Astrophysics Data System (ADS)

    Kishore, Bhaskar; Bazin, Pierre-Louis; Pham, Dzung L.

    2009-02-01

    We describe BrainIACS, a web-based medical image processing system that permits and facilitates algorithm developers to quickly create extensible user interfaces for their algorithms. Designed to address the challenges faced by algorithm developers in providing user-friendly graphical interfaces, BrainIACS is completely implemented using freely available, open-source software. The system, which is based on a client-server architecture, utilizes an AJAX front-end written using the Google Web Toolkit (GWT) and Java Servlets running on Apache Tomcat as its back-end. To enable developers to quickly and simply create user interfaces for configuring their algorithms, the interfaces are described using XML and are parsed by our system to create the corresponding user interface elements. Most of the commonly found elements such as check boxes, drop down lists, input boxes, radio buttons, tab panels and group boxes are supported. Some elements such as the input box support input validation. Changes to the user interface such as addition and deletion of elements are performed by editing the XML file or by using the system's user interface creator. In addition to user interface generation, the system also provides its own interfaces for data transfer, previewing of input and output files, and algorithm queuing. As the system is programmed using Java (and finally Java-script after compilation of the front-end code), it is platform independent with the only requirements being that a Servlet implementation be available and that the processing algorithms can execute on the server platform.

  17. Challenges in Implementing Strategies for Gender-Aware Teaching.

    ERIC Educational Resources Information Center

    Gilbert, Melissa C.; Gilbert, Lucia Albino

    2002-01-01

    Discusses the negative consequences of gender stereotyping in the mathematics classroom, especially for girls. Addresses possible challenges associated with creating a safe learning environment and combating gender stereotypes. Describes difficulties in various settings in the mathematics classroom and explores challenges associated with…

  18. Conducting pharmaceutical R&D in India - Critical components of entry strategies.

    PubMed

    Gulati, Rajiv

    2008-11-01

    In the face of challenges associated with expiring patents, the rising cost of R&D and pressure on pricing, most major pharmaceutical companies are seeking ways to enhance productivity, reduce costs and augment the late-stage new-product pipeline. Exploiting the R&D capabilities in India is one option that can be helpful in achieving these goals. However, considering the challenges involved, important considerations must be incorporated to ensure that an appropriate R&D strategy is meticulously implemented. In creating suitable strategies, it is important to understand the historical perspective that provides insight into the relative strengths of companies in India across the R&D value chain. In addition, the ability of a company to take risks and commit to a long-term investment will largely determine the model that is selected. To implement a given model, an understanding of cultural differences and infrastructural challenges that must be overcome is extremely important. The ultimate factor that determines success or failure, however, lies within the organization. Preparing an organization by establishing appropriate structures and processes is imperative.

  19. Challenges to clinical deployment of upper limb neuroprostheses.

    PubMed

    Triolo, R; Nathan, R; Handa, Y; Keith, M; Betz, R R; Carroll, S; Kantor, C

    1996-04-01

    The technology for functional neuromuscular stimulation (FNS) as a means of providing upper limb function to people with tetraplegia has been under development by three clinical research groups for almost two decades. This paper presents the current status of the clinical trials of three FNS systems: a noninvasive system built into a cosmetic forearm splint, a 30-channel percutaneous system, and an 8-channel implantable system. The complexity of FNS systems and the unique characteristics of the individuals to whom they are applied combine to create many clinical and technical challenges that must be addressed before the devices can be deployed. The emerging challenges to widespread clinical introduction of FNS systems for hand and arm function are identified and analyzed. In addition to the demands of designed and conducting the clinical trials to satisfy regulatory requirements, the lack of knowledge, skepticism, and the complacency on the part of potential FNS recipients, as well as of rehabilitation professionals, must be overcome through education and careful consideration of economic and societal factors in the design of clinical systems.

  20. Sprawl and the Management of Urban Greenfrastructure

    Treesearch

    John F. Dwyer; Gina M. Childs

    2003-01-01

    Sprawl and associated developments create new opportunities and challenges for the management of green infrastructure across the urban to rural landscape. This paper outlines these opportunities and challenges.

  1. Compelling teaching with the four Cs: caring, comedy, creativity, and challenging.

    PubMed

    Story, Lachel; Butts, Janie B

    2010-05-01

    The traditional classroom, particularly in nursing, often is stifling to students and teachers. A dynamic co-learning experience creates a potential to move students from merely obtaining knowledge to practice. This article presents an exemplar of the transformative learning process within the nursing education setting. The concepts forming this compelling teaching approach are caring, comedy, creativity, and challenging (the four Cs). Through this innovative teaching method, opportunities are created for authentic co-learning to occur.

  2. Thriving Earth Exchange: AGU's new grand challenge

    NASA Astrophysics Data System (ADS)

    McEntee, Chris; Williams, Billy

    2012-11-01

    Imagine a world where scientists are acknowledged and celebrated for their good works. Imagine being able to make a powerful impact, applying your expertise and experience to create real solutions to ensure a sustainable future. Now imagine those two ideas linked: AGU scientists engaged in creating solutions that are recognized and celebrated for their positive impact on our world. The AGU Grand Challenge: Thriving Earth Exchange, a new idea from our member leaders, is about making this dream real.

  3. Creating Student Engagement Through Immersion: Exploring the MT6 Shipwreck in Puget Sound via Submersible, Using a Team Challenge Format

    NASA Astrophysics Data System (ADS)

    Sarason, C. P.; Hartzler, R.; Anderson, A.

    2016-02-01

    Educational literature has many stories describing the "aha" moment that teachers are privileged to observe: a student who suddenly grasps a concept (ding!), dives into an activity (whee!) or works tirelessly to complete a complicated project (wow!). Designing moments like these for students can be one of the great joys of teaching. Experiencing such a moment can have a lasting impact on student engagement and motivation, and is the underlying rationale for the importance of creating a wide array of outreach efforts, from field work to telepresence activities.During the spring of 2015, OceanGate Foundation and Seattle Central College partnered on a pilot program to design a program that had this kind of impact and created the Open The Oceans Challenge. Student teams responded to our Request for Proposal (RFP), which was centered around the exploration of a shipwreck in 150 meters of water just off the Seattle waterfront, the MT-6. Students spent a significant amount of time crafting their proposals and reported that they enjoyed the process of writing the proposal as a team. The two winning teams accompanied us on a series of submersible dives performed by OceanGate, Inc. and worked up the results afterward. In addition to researching the MT-6 wreck and documenting what they found, students were able to do basic observational research on the wreck, providing sonar and photographic data that will help form the basis of future expeditions to this site.We report on lessons learned from this pilot — the impact for the small set of students involved in this project was profound, but how can we expand the reach of such activities? Results from this experience suggest that providing a highly engaging topic and expedition may not be enough to inspire an "aha" moment that creates lasting engagement; the scaffolding and mentorship that surrounds a rich experience is also critical.

  4. Tri-Agency Coordination: Challenges and Successes in Creating a Community of Practice among Climate Change Education Principal Investigators funded by NASA, NOAA, and NSF

    NASA Astrophysics Data System (ADS)

    Schoedinger, S. E.; McDougall, C.; Karsten, J. L.; Campbell, D.; Pippin, M. R.; Chambers, L. H.

    2013-12-01

    The effort needed for comprehensive climate change education is far greater than any one institution, education sector, or even federal agency can handle. Recognizing a need to synergistically combine efforts, NSF, NASA, and NOAA have created a collaborative community of their climate change education principal investigators (PIs) through tri-agency coordination. The goals of this tri-agency collaboration are to leverage existing resources, minimize duplicate efforts, and facilitate communication among this emergent community of scientists and educators. NASA, NOAA, and NSF work together to strategically coordinate and support a portfolio of projects focused on climate literacy and education in formal and informal learning environments. The activities of the tri-agency collaboration, including annual meetings for PIs, a catalog of the agencies collective investments in climate change education and the ongoing development of a nascent common evaluation framework, have created a strong national network for effectively engaging diverse audiences with the principles of climate literacy (see Eos Vol. 92, No. 24, 14 June 2011). Last year, after 3 years of active collaboration, similar programs underway at other U.S. Global Change Research Program agencies: the EPA, National Institutes for Environmental Health Sciences, and USDA, were engaged in the collaboration. And, in an attempt to understand the interests of the private sector in this arena, conversations have begun with private philanthropic organizations. This year, as many of the funded projects are maturing, the PI meeting will have a focus on bringing this community together to create a science-theme based tangible outcome that can move the field of climate change education forward. Additional outcomes from this PI meeting will be presented as well as the challenges that were encountered in bringing together institutions with diverse missions, and approaches developed to ensure all parties feel they're benefiting from the collaboration.

  5. Techniques for High Contrast Imaging in Multi-Star Systems II: Multi-Star Wavefront Control

    NASA Technical Reports Server (NTRS)

    Sirbu, D.; Thomas, S.; Belikov, R.

    2017-01-01

    Direct imaging of exoplanets represents a challenge for astronomical instrumentation due to the high-contrast ratio and small angular separation between the host star and the faint planet. Multi-star systems pose additional challenges for coronagraphic instruments because of the diffraction and aberration leakage introduced by the additional stars, and as a result are not planned to be on direct imaging target lists. Multi-star wavefront control (MSWC) is a technique that uses a coronagraphic instrument's deformable mirror (DM) to create high-contrast regions in the focal plane in the presence of multiple stars. Our previous paper introduced the Super-Nyquist Wavefront Control (SNWC) technique that uses a diffraction grating to enable the DM to generate high-contrast regions beyond the nominal controllable region. These two techniques can be combined to generate high-contrast regions for multi-star systems at any angular separations. As a case study, a high-contrast wavefront control (WC) simulation that applies these techniques shows that the habitable region of the Alpha Centauri system can be imaged reaching 8 times 10(exp -9) mean contrast in 10 percent broadband light in one-sided dark holes from 1.6-5.5 lambda (wavelength) divided by D (distance).

  6. Student nurses' experience working with mentally challenged individuals in South Africa.

    PubMed

    Janse VAN Rensburg, E S; Poggenpoel, M; Myburgh, C P H

    2012-11-01

    South African student nurses experience emotional discomfort that might influence their adjustment and coping while working with mentally challenged individuals. Adjustment and coping might impact on their mental health and support needed while working in this challenging context. Student nurses working with mentally challenged individuals experience emotional discomfort that may result in work-related stress. The experiences of student nurses working with mentally challenged individuals were explored and described as it may influence their adjustment, coping and result in work-related stress, impacting on their mental health. The study used a qualitative, explorative, descriptive, contextual research design with a case study as strategy. Thirteen student nurses from a specific higher educational institution in Gauteng, South Africa, participated in the focus group interviews. The researcher utilized reflective journals, a reflective letter, naïve sketches, drawings and field notes to collect data. Data analysis was done according to Tesch's descriptive method of open coding and theme analysis. A central storyline emerged where student nurses described working with mentally challenged individuals as a process of personal transformation that was initiated by an engagement on a deeper emotional level with these individuals. The process of personal transformation started a journey towards the discovery of meaning for the self, as student nurses. Student nurses working in challenging environments during their training may experience emotional discomfort and need additional support in coping and adjustment within this context. The nurse educator plays an important role in providing this support to manage work-related stress as well as in creating learning opportunities for the student nurses working in challenging contexts. © 2012 Blackwell Publishing.

  7. Large datasets, logistics, sharing and workflow in screening.

    PubMed

    Cook, Tessa S

    2018-03-29

    Cancer screening initiatives exist around the world for different malignancies, most frequently breast, colorectal, and cervical cancer. A number of cancer registries exist to collect relevant data, but while these data may include imaging findings, they rarely, if ever, include actual images. Additionally, the data submitted to the registry are usually correlated with eventual cancer diagnoses and patient outcomes, rather than used with the individual's future screenings. Developing screening programs that allow for images to be submitted to a central location in addition to patient meta data and used for comparison to future screening exams would be very valuable in increasing access to care and ensuring that individuals are effectively screened at appropriate intervals. It would also change the way imaging results and additional patient data are correlated to eventual outcomes. However, it introduces logistical challenges surrounding secure storage and transmission of data to subsequent screening sites. In addition, in the absence of standardized protocols for screening, comparing current and prior imaging, especially from different equipment, can be challenging. Implementing a large-scale screening program with an image-enriched screening registry-effectively, an image-enriched electronic screening record-also requires that incentives exist for screening sites, physicians, and patients to participate; to maximize coverage, participation may have to be supported by government agencies. Workflows will also have to be adjusted to support registry participation for all screening patients in an effort to create a large, robust data set that can be used for future screening efforts as well as research initiatives.center.

  8. Creating a Pilot Educational Psychiatry Website: Opportunities, Barriers, and Next Steps.

    PubMed

    Torous, John; O'Connor, Ryan; Franzen, Jamie; Snow, Caitlin; Boland, Robert; Kitts, Robert

    2015-11-05

    While medical students and residents may be utilizing websites as online learning resources, medical trainees and educators now have the opportunity to create such educational websites and digital tools on their own. However, the process and theory of building educational websites for medical education have not yet been fully explored. To understand the opportunities, barriers, and process of creating a novel medical educational website. We created a pilot psychiatric educational website to better understand the options, opportunities, challenges, and processes involved in the creation of a psychiatric educational website. We sought to integrate visual and interactive Web design elements to underscore the potential of such Web technology. A pilot website (PsychOnCall) was created to demonstrate the potential of Web technology in medical and psychiatric education. Creating an educational website is now technically easier than ever before, and the primary challenge no longer is technology but rather the creation, validation, and maintenance of information for such websites as well as translating text-based didactics into visual and interactive tools. Medical educators can influence the design and implementation of online educational resources through creating their own websites and engaging medical students and residents in the process.

  9. Creating a Pilot Educational Psychiatry Website: Opportunities, Barriers, and Next Steps

    PubMed Central

    O'Connor, Ryan; Franzen, Jamie; Snow, Caitlin; Boland, Robert; Kitts, Robert

    2015-01-01

    Background While medical students and residents may be utilizing websites as online learning resources, medical trainees and educators now have the opportunity to create such educational websites and digital tools on their own. However, the process and theory of building educational websites for medical education have not yet been fully explored. Objective To understand the opportunities, barriers, and process of creating a novel medical educational website. Methods We created a pilot psychiatric educational website to better understand the options, opportunities, challenges, and processes involved in the creation of a psychiatric educational website. We sought to integrate visual and interactive Web design elements to underscore the potential of such Web technology. Results A pilot website (PsychOnCall) was created to demonstrate the potential of Web technology in medical and psychiatric education. Conclusions Creating an educational website is now technically easier than ever before, and the primary challenge no longer is technology but rather the creation, validation, and maintenance of information for such websites as well as translating text-based didactics into visual and interactive tools. Medical educators can influence the design and implementation of online educational resources through creating their own websites and engaging medical students and residents in the process. PMID:27731837

  10. Multi-material 3D Models for Temporal Bone Surgical Simulation.

    PubMed

    Rose, Austin S; Kimbell, Julia S; Webster, Caroline E; Harrysson, Ola L A; Formeister, Eric J; Buchman, Craig A

    2015-07-01

    A simulated, multicolor, multi-material temporal bone model can be created using 3-dimensional (3D) printing that will prove both safe and beneficial in training for actual temporal bone surgical cases. As the process of additive manufacturing, or 3D printing, has become more practical and affordable, a number of applications for the technology in the field of Otolaryngology-Head and Neck Surgery have been considered. One area of promise is temporal bone surgical simulation. Three-dimensional representations of human temporal bones were created from temporal bone computed tomography (CT) scans using biomedical image processing software. Multi-material models were then printed and dissected in a temporal bone laboratory by attending and resident otolaryngologists. A 5-point Likert scale was used to grade the models for their anatomical accuracy and suitability as a simulation of cadaveric and operative temporal bone drilling. The models produced for this study demonstrate significant anatomic detail and a likeness to human cadaver specimens for drilling and dissection. Simulated temporal bones created by this process have potential benefit in surgical training, preoperative simulation for challenging otologic cases, and the standardized testing of temporal bone surgical skills. © The Author(s) 2015.

  11. Leadership Skills and Challenges in Hospitality Management Education

    ERIC Educational Resources Information Center

    Kalargyrou, Valentini

    2009-01-01

    Leaders in hospitality management education face diverse challenges in today's competitive and changing environment. Evolving demands from superiors, financial challenges, and faculty and students increasing demands, create a turbulent environment in which administrators must thrive. One of the keys in being effective leaders is the application of…

  12. 78 FR 33849 - Battery-Powered Medical Devices Workshop: Challenges and Opportunities; Public Workshop; Request...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-05

    ...] Battery-Powered Medical Devices Workshop: Challenges and Opportunities; Public Workshop; Request for.... The Food and Drug Administration (FDA) is announcing the following public workshop entitled ``Battery... create awareness of the challenges related to battery-powered medical devices and collaboratively develop...

  13. Creation of Functional Micro/Nano Systems through Top-down and Bottom-up Approaches

    PubMed Central

    Wong, Tak-Sing; Brough, Branden; Ho, Chih-Ming

    2009-01-01

    Mimicking nature’s approach in creating devices with similar functional complexity is one of the ultimate goals of scientists and engineers. The remarkable elegance of these naturally evolved structures originates from bottom-up self-assembly processes. The seamless integration of top-down fabrication and bottom-up synthesis is the challenge for achieving intricate artificial systems. In this paper, technologies necessary for guided bottom-up assembly such as molecular manipulation, molecular binding, and the self assembling of molecules will be reviewed. In addition, the current progress of synthesizing mechanical devices through top-down and bottom-up approaches will be discussed. PMID:19382535

  14. Nucleation and growth of the Naica giant gypsum crystals.

    PubMed

    Otálora, Fermín; García-Ruiz, JuanMa

    2014-04-07

    The Cave of Giant Crystals in the Naica mine (Mexico) is one of the most amazing displays of mineral beauty ever created in nature. In addition to the colossal crystals of gypsum, which in some cases exceed eleven meters in length and one meter in thickness, the scenery fashioned by the crystalline beams that thrust through the darkness of the cave from floor to ceiling with a luster like moonlight is a unique example of harmony based on crystal symmetry. We review the crystallogenesis of this remarkable and challenging phenomenon of mineralization near equilibrium that can be used to teach the basics of nucleation and crystal growth.

  15. Investment in Open Innovation Service Providers: NASA's Innovative Strategy for Solving Space Exploration Challenges

    NASA Technical Reports Server (NTRS)

    Fogarty, Jennifer A.; Rando, Cynthia; Baumann, David; Richard, Elizabeth; Davis, Jeffrey

    2010-01-01

    In an effort to expand routes for open communication and create additional opportunities for public involvement with NASA, Open Innovation Service Provider (OISP) methodologies have been incorporated as a tool in NASA's problem solving strategy. NASA engaged the services of two OISP providers, InnoCentive and Yet2.com, to test this novel approach and its feasibility in solving NASA s space flight challenges. The OISPs were chosen based on multiple factors including: network size and knowledge area span, established process, methodology, experience base, and cost. InnoCentive and Yet2.com each met the desired criteria; however each company s approach to Open Innovation is distinctly different. InnoCentive focuses on posting individual challenges to an established web-based network of approximately 200,000 solvers; viable solutions are sought and granted a financial award if found. Based on a specific technological need, Yet2.com acts as a talent scout providing a broad external network of experts as potential collaborators to NASA. A relationship can be established with these contacts to develop technologies and/or maintained as an established network of future collaborators. The results from the first phase of the pilot study have shown great promise for long term efficacy of utilizing the OISP methodologies. Solution proposals have been received for the challenges posted on InnoCentive and are currently under review for final disposition. In addition, Yet2.com has identified new external partners for NASA and we are in the process of understanding and acting upon these new opportunities. Compared to NASA's traditional routes for external problem solving, the OISP methodologies offered NASA a substantial savings in terms of time and resources invested. In addition, these strategies will help NASA extend beyond its current borders to build an ever expanding network of experts and global solvers.

  16. Bringing Seismology's Grand Challenges to the Undergraduate Classroom

    NASA Astrophysics Data System (ADS)

    Benoit, M. H.; Taber, J.; Hubenthal, M.

    2011-12-01

    The "Seismological Grand Challenges in Understanding Earth's Dynamic Systems," a community-written long-range science plan for the next decade, poses 10 questions to guide fundamental seismological research. Written in an approachable fashion suitable for policymakers, the broad questions and supporting discussion contained in this document offer an ideal framework for the development of undergraduate curricular materials. Leveraging this document, we have created a collection of inquiry-based classroom modules that utilize authentic data to modernize seismological instruction in 100 and 200 level undergraduate courses. The modules not only introduce undergraduates to the broad questions that the seismological community seeks to answer in the future but also showcase the numerous areas where modern seismological research is actively contributing to our understanding of fundamental Earth processes. To date 6 in-depth explorations that correspond to the Grand Challenges document have been developed. The specific topics for each exploration were selected to showcase modern seismological research while also covering topics commonly included in the curriculum of these introductory classes. Examples of activities that have been created and their corresponding Grand Challenge include: -A guided inquiry that introduces students to episodic tremor and slip and compares the GPS and seismic signatures of ETS with those produced from standard tectonic earthquakes (Grand Challenge "How do faults slip?"). - A laboratory exercise where students engage in b-value mapping of volcanic earthquakes to assess potential eruption hazards (How do magmas ascend and erupt?). - A module that introduce students to glacial earthquakes in Greenland and compares their frequency and spatial distribution to tectonic earthquakes (How do processes in the ocean and atmosphere interact with the solid Earth?). What is the relationship between stress and strain in the lithosphere? - An activity that examines the phenomena of earthquake triggering by distant events. (What is the relationship between stress and strain in the lithosphere?) To enhance the usefulness of these resources, all have been developed in a modular fashion which allows instructors to pick and choose some (or all) of these resources for integration in to the scope and sequence of their course. In addition to the in-depth labs, we also have created a number of mini-activities and visual material for the classroom, including think-pair-shares and lecture tutorials based on the following Grand Challenges: -What is the lithosphere-asthenosphere boundary? -How do plate boundary systems evolve? -How do temperature and composition variations control mantle and core convection? -How are Earth's internal boundaries affected by dynamics? Over the next year we will be pilot testing and refining these activities at a number of institutions, including 2- and 4-year colleges, and the materials will eventually be disseminated online and through small training workshops. Current drafts of some of the activities are available at www.tcnj.edu/~benoit/grandchallenges.

  17. Social determinants of health in selected slum areas in Jordan: challenges and policy directions.

    PubMed

    Ajlouni, Musa T

    2016-01-01

    The unplanned urbanization in Jordan has over time created many informal settlements "slums" around big cities as Amman, Zerka and Aqaba. The purpose of this study was to highlight the most common challenges related to social determinants of health in two selected slum areas in Amman and Aqaba and suggest policy directions and interventions to meet these challenges. In addition to a prestructured interview with all household heads living in the two slum sites, focus group meetings with a purposefully selected sample of 12 slum dwellers in each site were used to assess the structural and intermediary determinants of health as perceived by slum residents in the two study locations. The study found that slum residents in the two locations suffer from many challenges as severe poverty; unemployment; illiteracy and low education attainments; gender discrimination; insufficient and poor diet; social and official exclusion; unhealthy environment; lack of water supply, electricity and basic sanitation facilities; high prevalence of diseases; and insufficient and inappropriate health services. Specific policy directions to meet these challenges were recommended and grouped into three main clusters: social protection, social inclusion and empowerment. New plans and tools should be developed by local authorities in Jordan to understand, protect, include and empower those vulnerable people who are forced to live in these unhealthy and inhuman environments. Copyright © 2014 John Wiley & Sons, Ltd.

  18. [Status and challenges related to creating a healthy food environment: a questionnaire survey for public health dieticians].

    PubMed

    Sakaguchi, Keiko; Takemi, Yukari

    2017-01-01

    Objectives Creating a healthy food environment is crucial for healthful longevity in Japan. This study aimed to provide an overview of the status and challenges related to creating that environment through prefectural public health centers.Methods Public health dieticians working at 489 prefectural public health centers in March 2015 individually completed an anonymous self-administered questionnaire. Berelson's content analysis was utilized for response analysis.Results Data from 359 (response rate: 74.3%) prefectural public health centers, involving 599 public health dieticians, were included in the analysis. More than 80% of the prefectural public health centers implemented a registration system for dining facilities such as restaurants. Furthermore, greater than 80% of the public health dietitians thought that creating a healthy food environment was an important aspect of their work mission. On the other hand, more than 50% of these dieticians expressed dissatisfaction in their role. In terms of evaluation, the public health centers only monitored the number of registered facilities, with few other evaluations conducted. Approximately 80% of the participants requested national guidelines and/or some legal support from the Ministry of Health, Labor, and Welfare and/or the prefectural administration.Conclusion This study demonstrated that there are challenges related to creating a healthy food environment through prefectural health centers. Improving the evaluation methods and government/administrative provision of national guidelines and/or legal supports were identified as courses of action.

  19. Challenges of Recruiting Candidates with Strong Academic Credentials

    ERIC Educational Resources Information Center

    Denton, Jon; Davis, Trina

    2007-01-01

    A major challenge to improving science education lies in the shortage of qualified science teachers. A potential solution to this challenge consists of directing the energy and talent of graduate students and postdoctoral scientists to reinvigorate science education in schools. This requires creating new, more accessible pathways for science…

  20. Student Media Production to Meet Challenges in Climate Change Science Education

    ERIC Educational Resources Information Center

    Rooney-Varga, Juliette N.; Brisk, Angelica Allende; Adams, Elizabeth; Shuldman, Elizabeth; Rath, Kenneth

    2014-01-01

    While the need for effective climate change education is growing, this area of geoscience also poses unique educational challenges. These challenges include the politicization of climate change, the psychological and affective responses it elicits, and common misconceptions, which can all create barriers to learning. Here, we present an…

  1. The Jet Travel Challenge

    ERIC Educational Resources Information Center

    Roman, Harry T.

    2007-01-01

    Airplane travelers are dismayed by the long lines and seemingly chaotic activities that precede boarding a full airplane. Surely, the one who can solve this problem is going to make many travelers happy. This article describes the Jet Travel Challenge, an activity that challenges students to create some alternatives to this now frustrating…

  2. Building Connections: Strategies to Address Rurality and Accessibility Challenges

    ERIC Educational Resources Information Center

    Hartman, Sara; Hines-Bergmeier, Jennifer

    2015-01-01

    Operating a museum in a high poverty, underserved area creates many challenges related to accessibility, programming, and funding. Over the course of nearly a decade, the Ohio Valley Museum of Discovery (OVMoD) has identified several organizational practices that help mitigate these challenges. Located in the southeastern corner of Appalachian…

  3. Application of the instructional congruence framework: Developing supplemental materials for English language learners

    NASA Astrophysics Data System (ADS)

    Drews, Tina Skjerping

    2009-12-01

    This dissertation is a study of the instructional congruence framework as it was used to develop and pilot a supplemental science unit on energy and the environment for sixth grade students in Arizona. With the growing linguistic and cultural diversity of children in American schools, congruent materials are more important now than ever before. The supplemental materials were designed by the researcher and underwent a six person, three educator and three engineer, panel review. The revised materials were then piloted in two sixth grade classrooms in the Southwest with high numbers of English language learners. Classroom observation, teacher interviews, and the classroom observation protocol were utilized to understand the fidelity to the instructional congruence framework. The fidelity of implementation of materials was subject to the realities of varied educational contexts. Piloting materials in urban contexts with diverse students involved additional challenges. The results of the study explore the challenges in creating instructionally congruent materials for diverse students in urban contexts. Recommendations are provided for curriculum developers that undertake the task of creating instructionally congruent materials and emphasize the need to devise innovative methods of creation, while understanding that there is no perfect solution. The education community as a whole could benefit from incorporating and synthesizing the instructional congruence framework in order to provide maximum opportunities in science for all students.

  4. Sustainability in a Hospital-Based Biobank and University-Based DNA Biorepository: Strategic Roadmaps.

    PubMed

    Seiler, Catherine Y; Eschbacher, Jennifer; Bowser, Robert; LaBaer, Joshua

    2015-12-01

    Sustainability in the biobanking community has recently become an important and oft-discussed issue as biorepositories struggle to balance limited external funding and complex cost recovery models with high operating costs and the desire to provide the highest quality materials and services to the research community. A multi-faceted view of biobanking sustainability requires consideration of operational and social sustainability in addition to the historical focus exclusively on financial sustainability. Planning and implementing this three pillar model creates a well-rounded biorepository that meets the needs of all the major stakeholders: the funders, the patients/depositors, and the researcher recipients. Often the creation of a detailed business plan is the first step to develop goals and objectives that lead down a path towards sustainability. The definition of sustainability and the complexity of a sustainable business plan may differ for each biorepository. The DNASU Plasmid Repository at Arizona State University stores and distributes DNA plasmids to researchers worldwide, and the Biobank Core Facility at St. Joseph's Hospital and Barrow Neurological Institute consents patients and collects, stores, and distributes human tissue and blood samples. We will discuss these two biorepositories, their similar and different approaches to sustainability and business planning, their challenges in creating and implementing their sustainability plan, and their responses to some of these challenges. From these experiences, the biobanks share lessons learned about planning for sustainability that are applicable to all biorepositories.

  5. IED Cleanup: A Cooperative Classroom Robotics Challenge--The Benefits and Execution of a Cooperative Classroom Robotics Challenge

    ERIC Educational Resources Information Center

    Piotrowski, Mark; Kressly, Rich

    2009-01-01

    This article describes a cooperative classroom robotics challenge named "IED Cleanup". This classroom challenge was created to incorporate a humanitarian project with the use of a robotics design system in order to remove simulated IEDs (Improvised Explosive Devices) to a detonation zone within a specified amount of time. Throughout the activity,…

  6. Burnout Factories: The Challenge of Retaining Great Teachers in Charter Schools

    ERIC Educational Resources Information Center

    Fusco, Mark

    2017-01-01

    In its well-intentioned effort to create alternatives to public school dropout factories, the charter school sector has created teacher burnout factories. But it does not have to be this way. Charter schools can continue to maintain high standards while creating a more sustainable work environment for teachers. This article examines the teacher…

  7. Creating "Third Spaces": Promoting Learning through Dialogue

    ERIC Educational Resources Information Center

    Wilhelm, Jeffrey D.

    2010-01-01

    Wilhelm offers us a definition of "third spaces" as "more democratic and dialogic spaces than a classroom, as well as a metaphor for a space in which new, hybrid, and challenging discourses and real-world knowledge and applications are created." With helpful background and examples, he urges us to create such spaces for our students, adamant that…

  8. Engineering as a Social Activity: Preparing Engineers to Thrive in the Changing World of Work

    ERIC Educational Resources Information Center

    Joyner, Fredricka F.; Mann, Derek T. Y.; Harris, Todd

    2012-01-01

    Key macro-trends are combining to create a new work context for the practice of engineering. Telecommuting and virtual teams create myriad possibilities and challenges related to managing work and workers. Social network technology tools allow for unprecedented global, 24/7 collaboration. Globalization has created hyper-diverse organizations,…

  9. Rise to the Challenge: A Business Guide to Creating a Workforce Investment System That Makes Sense.

    ERIC Educational Resources Information Center

    2000

    This document explains how employers can participate in creating a new workforce investment system that is market driven, comprehensive, portable, accountable, customer focused, responsive, flexible, and customized. The guide details immediate and future steps employers can take at the state and local levels to influence the process of creating a…

  10. A Field-Tested Task Analysis for Creating Single-Subject Graphs Using Microsoft[R] Office Excel

    ERIC Educational Resources Information Center

    Lo, Ya-yu; Konrad, Moira

    2007-01-01

    Creating single-subject (SS) graphs is challenging for many researchers and practitioners because it is a complex task with many steps. Although several authors have introduced guidelines for creating SS graphs, many users continue to experience frustration. The purpose of this article is to minimize these frustrations by providing a field-tested…

  11. A social media intervention to improve hypoglycemia management at a multicenter hospital: a quality improvement pilot for clinical nurses.

    PubMed

    De Sousa, Filomena; Jackson, Jennifer; Knight, Ruth; Cloutier, Edith; Basa, Rosemary; Fourney, Anne; Devecseri, Kathleen

    2018-02-01

    Hypoglycemia poses significant risk to inpatients. Nursing management of hypoglycemia is a challenge, despite established best practice guidelines. Social media is an effective tool for sharing information and could overcome barriers to clinical education at a multicenter hospital. The purpose of this quality improvement intervention was to create and disseminate social media posts about best practices in hypoglycemia management. An unmatched pre-and post-survey assessed nursing knowledge of hypoglycemia management. Social media posts were created to visually outline the steps for hypoglycemia management over 2 weeks, across a nursing social media platform. We assessed the reach of the posts via Facebook and a survey. The posts reached 2962 users during the first week, and 1491 users the second week. A social media intervention can have a substantial reach and distribute information across a multicenter hospital. Additional study is needed to determine what factors could support an increase in nursing knowledge through a social media campaign.

  12. A knowledge discovery object model API for Java

    PubMed Central

    Zuyderduyn, Scott D; Jones, Steven JM

    2003-01-01

    Background Biological data resources have become heterogeneous and derive from multiple sources. This introduces challenges in the management and utilization of this data in software development. Although efforts are underway to create a standard format for the transmission and storage of biological data, this objective has yet to be fully realized. Results This work describes an application programming interface (API) that provides a framework for developing an effective biological knowledge ontology for Java-based software projects. The API provides a robust framework for the data acquisition and management needs of an ontology implementation. In addition, the API contains classes to assist in creating GUIs to represent this data visually. Conclusions The Knowledge Discovery Object Model (KDOM) API is particularly useful for medium to large applications, or for a number of smaller software projects with common characteristics or objectives. KDOM can be coupled effectively with other biologically relevant APIs and classes. Source code, libraries, documentation and examples are available at . PMID:14583100

  13. One-Micron Beams for Macromolecular Crystallography at GM/CA-CAT

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Yoder, D. W.; Sanishvili, R.; Xu, S.

    2010-06-23

    GM/CA-CAT has developed a 1-{mu}m beam for challenging micro-diffraction experiments with macromolecular crystals (e.g. small crystals) and for radiation damage studies. Reflective (Kirkpatrick-Baez mirrors) and diffractive (Fresnel zone plates) optics have been used to focus the beam. Both cases are constrained by the need to maintain a small beam convergence. Using two different zone plates, 1.0x1.0 and 0.8x0.9 {mu}m{sup 2} (VxH,FWHM) beams were created at 15.2 keV and 18.5 keV, respectively. Additionally, by introducing a vertical focusing mirror upstream of the zone plate, a line focus at 15.2 keV was created (28x1.4 {mu}m{sup 2} VxH,FWHM) with the line oriented perpendicularmore » to the X-ray polarization and the crystal rotation axis. Crystal-mounting stages with nanometer resolution have been assembled to profile these beams and to perform diffraction experiments.« less

  14. Sparse synthetic aperture with Fresnel elements (S-SAFE) using digital incoherent holograms

    PubMed Central

    Kashter, Yuval; Rivenson, Yair; Stern, Adrian; Rosen, Joseph

    2015-01-01

    Creating a large-scale synthetic aperture makes it possible to break the resolution boundaries dictated by the wave nature of light of common optical systems. However, their implementation is challenging, since the generation of a large size continuous mosaic synthetic aperture composed of many patterns is complicated in terms of both phase matching and time-multiplexing duration. In this study we present an advanced configuration for an incoherent holographic imaging system with super resolution qualities that creates a partial synthetic aperture. The new system, termed sparse synthetic aperture with Fresnel elements (S-SAFE), enables significantly decreasing the number of the recorded elements, and it is free from positional constrains on their location. Additionally, in order to obtain the best image quality we propose an optimal mosaicking structure derived on the basis of physical and numerical considerations, and introduce three reconstruction approaches which are compared and discussed. The super-resolution capabilities of the proposed scheme and its limitations are analyzed, numerically simulated and experimentally demonstrated. PMID:26367947

  15. Web Design for Space Operations: An Overview of the Challenges and New Technologies Used in Developing and Operating Web-Based Applications in Real-Time Operational Support Onboard the International Space Station, in Astronaut Mission Planning and Mission Control Operations

    NASA Technical Reports Server (NTRS)

    Khan, Ahmed

    2010-01-01

    The International Space Station (ISS) Operations Planning Team, Mission Control Centre and Mission Automation Support Network (MAS) have all evolved over the years to use commercial web-based technologies to create a configurable electronic infrastructure to manage the complex network of real-time planning, crew scheduling, resource and activity management as well as onboard document and procedure management required to co-ordinate ISS assembly, daily operations and mission support. While these Web technologies are classified as non-critical in nature, their use is part of an essential backbone of daily operations on the ISS and allows the crew to operate the ISS as a functioning science laboratory. The rapid evolution of the internet from 1998 (when ISS assembly began) to today, along with the nature of continuous manned operations in space, have presented a unique challenge in terms of software engineering and system development. In addition, the use of a wide array of competing internet technologies (including commercial technologies such as .NET and JAVA ) and the special requirements of having to support this network, both nationally among various control centres for International Partners (IPs), as well as onboard the station itself, have created special challenges for the MCC Web Tools Development Team, software engineers and flight controllers, who implement and maintain this system. This paper presents an overview of some of these operational challenges, and the evolving nature of the solutions and the future use of COTS based rich internet technologies in manned space flight operations. In particular this paper will focus on the use of Microsoft.s .NET API to develop Web-Based Operational tools, the use of XML based service oriented architectures (SOA) that needed to be customized to support Mission operations, the maintenance of a Microsoft IIS web server onboard the ISS, The OpsLan, functional-oriented Web Design with AJAX

  16. Perceived benefits and challenges of coordinated approaches to chronic disease prevention in state health departments.

    PubMed

    Allen, Peg; Sequeira, Sonia; Best, Leslie; Jones, Ellen; Baker, Elizabeth A; Brownson, Ross C

    2014-05-08

    Chronic disease prevention efforts have historically been funded categorically according to disease or risk factor. Federal agencies are now progressively starting to fund combined programs to address common risk. The purpose of this study was to inform transitions to coordinated chronic disease prevention by learning views on perceived benefits and challenges of a coordinated approach to funding. A national survey on evidence-based public health was conducted from March through May 2013 among state health department employees working in chronic disease prevention (N = 865). Participants were asked to rank the top 3 benefits and top 3 challenges in coordinating chronic disease approaches from provided lists and could provide additional responses. Descriptive analyses, χ(2) tests, and analysis of variance were conducted. The most common perceived benefits of coordinated approaches to chronic disease prevention were improved health outcomes, common risk factors better addressed, and reduced duplication of program efforts. The most common perceived challenges were funding restrictions, such as disease-specific performance measures; competing priorities; lack of communication across programs; funding might be reduced; agency not structured for program coordination; and loss of disease-specific partner support. Rankings of benefits and challenges were similar across states and participant roles; the perceived challenges "lack of communication across programs" (P = .02) and "funding might be reduced" differed by program area (P < .001). Findings can be used by funding agencies and state health departments for planning, training, and technical assistance. The information on perceived challenges demonstrates the need to improve communication across programs, enhance organizational support for coordinated approaches, and create benefits for organizational partners.

  17. Deep brain stimulation and ethics: perspectives from a multisite qualitative study of Canadian neurosurgical centers.

    PubMed

    Bell, Emily; Maxwell, Bruce; McAndrews, Mary Pat; Sadikot, Abbas; Racine, Eric

    2011-12-01

    Deep brain stimulation (DBS) is an approved neurosurgical intervention for motor disorders such as Parkinson disease. The emergence of psychiatric uses for DBS combined with the fact that it is an invasive and expensive procedure creates important ethical and social challenges in the delivery of care that need further examination. We endeavored to examine health care provider perspectives on ethical and social challenges encountered in DBS. Health care providers working in Canadian DBS surgery programs participated in a semistructured interview to identify and characterize ethical and social challenges of DBS. A content analysis of the interviews was conducted. Several key ethical issues, such as patient screening and resource allocation, were identified by members of neurosurgical teams. Providers described challenges in selecting patients for DBS on the basis of unclear evidence-based guidance regarding behavioral issues or cognitive criteria. Varied contexts of resource allocation, including some very challenging schemas, were also reported. In addition, the management of patients in the community was highlighted as a source of ethical and clinical complexity, given the need for coordinated long-term care. This study provides insights into the complexity of ethical challenges that providers face in the use of DBS across different neurosurgical centers. We propose actions for health care providers for the long-term care and postoperative monitoring of patients with DBS. More data on patient perspectives in DBS would complement the understanding of key challenges, as well as contribute to best practices, for patient selection, management, and resource allocation. Copyright © 2011 Elsevier Inc. All rights reserved.

  18. Pydpiper: a flexible toolkit for constructing novel registration pipelines.

    PubMed

    Friedel, Miriam; van Eede, Matthijs C; Pipitone, Jon; Chakravarty, M Mallar; Lerch, Jason P

    2014-01-01

    Using neuroimaging technologies to elucidate the relationship between genotype and phenotype and brain and behavior will be a key contribution to biomedical research in the twenty-first century. Among the many methods for analyzing neuroimaging data, image registration deserves particular attention due to its wide range of applications. Finding strategies to register together many images and analyze the differences between them can be a challenge, particularly given that different experimental designs require different registration strategies. Moreover, writing software that can handle different types of image registration pipelines in a flexible, reusable and extensible way can be challenging. In response to this challenge, we have created Pydpiper, a neuroimaging registration toolkit written in Python. Pydpiper is an open-source, freely available software package that provides multiple modules for various image registration applications. Pydpiper offers five key innovations. Specifically: (1) a robust file handling class that allows access to outputs from all stages of registration at any point in the pipeline; (2) the ability of the framework to eliminate duplicate stages; (3) reusable, easy to subclass modules; (4) a development toolkit written for non-developers; (5) four complete applications that run complex image registration pipelines "out-of-the-box." In this paper, we will discuss both the general Pydpiper framework and the various ways in which component modules can be pieced together to easily create new registration pipelines. This will include a discussion of the core principles motivating code development and a comparison of Pydpiper with other available toolkits. We also provide a comprehensive, line-by-line example to orient users with limited programming knowledge and highlight some of the most useful features of Pydpiper. In addition, we will present the four current applications of the code.

  19. Pydpiper: a flexible toolkit for constructing novel registration pipelines

    PubMed Central

    Friedel, Miriam; van Eede, Matthijs C.; Pipitone, Jon; Chakravarty, M. Mallar; Lerch, Jason P.

    2014-01-01

    Using neuroimaging technologies to elucidate the relationship between genotype and phenotype and brain and behavior will be a key contribution to biomedical research in the twenty-first century. Among the many methods for analyzing neuroimaging data, image registration deserves particular attention due to its wide range of applications. Finding strategies to register together many images and analyze the differences between them can be a challenge, particularly given that different experimental designs require different registration strategies. Moreover, writing software that can handle different types of image registration pipelines in a flexible, reusable and extensible way can be challenging. In response to this challenge, we have created Pydpiper, a neuroimaging registration toolkit written in Python. Pydpiper is an open-source, freely available software package that provides multiple modules for various image registration applications. Pydpiper offers five key innovations. Specifically: (1) a robust file handling class that allows access to outputs from all stages of registration at any point in the pipeline; (2) the ability of the framework to eliminate duplicate stages; (3) reusable, easy to subclass modules; (4) a development toolkit written for non-developers; (5) four complete applications that run complex image registration pipelines “out-of-the-box.” In this paper, we will discuss both the general Pydpiper framework and the various ways in which component modules can be pieced together to easily create new registration pipelines. This will include a discussion of the core principles motivating code development and a comparison of Pydpiper with other available toolkits. We also provide a comprehensive, line-by-line example to orient users with limited programming knowledge and highlight some of the most useful features of Pydpiper. In addition, we will present the four current applications of the code. PMID:25126069

  20. Environmental Control and Life Support Integration Strategy for 6-Crew Operations Stephanie Duchesne

    NASA Technical Reports Server (NTRS)

    Duchesne, Stephanie M.

    2009-01-01

    The International Space Station (ISS) crew compliment has increased in size from 3 to 6 crew members . In order to support this increase in crew on ISS, the United States on-orbit Segment (USOS) has been outfitted with a suite of regenerative Environmental Control and Life Support (ECLS) hardware including an Oxygen Generation System(OGS), Waste and Hygiene Compartment (WHC), and a Water Recovery System (WRS). The WRS includes the Urine Processor Assembly (UPA) and the Water Processor Assembly (WPA). With this additional life support hardware, the ISS has achieved full redundancy in its on-orbit life support system between the USOS and Russian Segment (RS). The additional redundancy created by the Regenerative ECLS hardware creates the opportunity for independent support capabilities between segments, and for the first time since the start of ISS, the necessity to revise Life Support strategy agreements. Independent operating strategies coupled with the loss of the Space Shuttle supply and return capabilities in 2010 offer new and unique challenges. This paper will discuss the evolution of the ISS Life Support hardware strategy in support of 6-Crew on ISS, as well as the continued work that is necessary to ensure the support of crew and ISS Program objectives through the life of station.

  1. Environmental Control and Life Support Integration Strategy for 6-Crew Operations

    NASA Technical Reports Server (NTRS)

    Duchesne, Stephanie M.; Tressler, Chad H.

    2010-01-01

    The International Space Station (ISS) crew complement has increased in size from 3 to 6 crew members. In order to support this increase in crew on ISS, the United States on-orbit Segment (USOS) has been outfitted with a suite of regenerative Environmental Control and Life Support (ECLS) hardware including an Oxygen Generation System (OGS), Waste and Hygiene Compartment (WHC), and a Water Recovery System (WRS). The WRS includes the Urine Processor Assembly (UPA) and the Water Processor Assembly (WPA). With this additional life support hardware, the ISS has achieved full redundancy in its on-orbit life support system between the t OS and Russian Segment (RS). The additional redundancy created by the Regenerative ECLS hardware creates the opportunity for independent support capabilities between segments, and for the first time since the start of ISS, the necessity to revise Life Support strategy agreements. Independent operating strategies coupled with the loss of the Space Shuttle supply and return capabilities in 2010 offer new and unique challenges. This paper will discuss the evolution of the ISS Life Support hardware strategy in support of 6-Crew on ISS, as well as the continued work that is necessary to ensure the support of crew and ISS Program objectives through the life of station

  2. Presidential Green Chemistry Challenge: 2013 Academic Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 2013 award winner, Prof Richard P. Wool of the University of Delaware, created high-performance materials using vegetable oils, feathers, and flax. Can be used as adhesives, composites, foams, and circuit boards.

  3. Presidential Green Chemistry Challenge: 2003 Greener Synthetic Pathways Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 2003 winner, Sud-Chemie, developed a synthesis for solid oxide catalysts used to make hydrogen and clean fuels. The process creates little wastewater, no nitrates, and no or little NOx.

  4. Overcoming Challenges of the Technological Age by Teaching Information Literacy Skills

    ERIC Educational Resources Information Center

    Burke, Melynda

    2010-01-01

    The technological age has forever altered every aspect of life and work. Technology has changed how people locate and view information. However, the transition from print to electronic formats has created numerous challenges for individuals to overcome. These challenges include coping with the massive amounts of information bombarding people and…

  5. Challenge Activities for the Physical Education Classroom: Considerations

    ERIC Educational Resources Information Center

    McKenzie, Emily; Tapps, Tyler; Fink, Kevin; Symonds, Matthew L.

    2018-01-01

    The purpose of this article is to provide physical education teachers with the tools to develop and implement challenge course-like activities in their physical education classes. The article also covers environmental considerations for teachers who have the desire to create a challenge-based classroom setting in order to reach a wider and more…

  6. Have It Their Way: Creating Personalized Online Challenges to Motivate Learners

    ERIC Educational Resources Information Center

    O'Neill, Barbara; Ensle, Karen

    2012-01-01

    This article describes the development and evaluation of an online health and personal finance behavior change challenge that can be adapted for other Extension subject matter areas. The Small Steps to Health and Wealth™ Challenge is a behaviorally focused activity in which registered users self-report health and financial behaviors and receive…

  7. The BuzzFeed Marketing Challenge: An Integrative Social Media Experience

    ERIC Educational Resources Information Center

    Cowley, Scott W.

    2017-01-01

    This article presents the BuzzFeed Marketing Challenge, which helps students gain integrative real-world marketing experience by selecting a target market, then creating, publishing, and promoting an article for the target market on entertainment publisher BuzzFeed.com. The challenge is for students to effectively use marketing strategy and…

  8. New Measure for Fathers of Children with Developmental Challenges

    ERIC Educational Resources Information Center

    Ly, A. R.; Goldberg, W. A.

    2014-01-01

    Background: There is a relative lack of measures tailored to the study of fathers of children with developmental challenges (DCs). The goal of the current study was to create and validate a brief measure designed to capture the perceptions and experiences of these fathers. The Fathers of Children with Developmental Challenges (FCDC) questionnaire…

  9. Goals for Education. Challenge to Lead: Mississippi

    ERIC Educational Resources Information Center

    Southern Regional Education Board, 2004

    2004-01-01

    The Southern Regional Education Board adopted Challenge to Lead education goals to focus and hold attention on educational improvement in its 16 states. This report provides an overview of Mississippi's progress toward meeting these important goals. Challenge to Lead asserts: "With almost half of the new jobs created in America in the 1990s,…

  10. Goals for Education. Challenge to Lead: Virginia

    ERIC Educational Resources Information Center

    Southern Regional Education Board, 2004

    2004-01-01

    The Southern Regional Education Board adopted Challenge to Lead education goals to focus and hold attention on educational improvement in its 16 states. This report provides an overview of Virginia's progress toward meeting these important goals. Challenge to Lead asserts: "With almost half of the new jobs created in America in the 1990s, SREB…

  11. Goals for Education. Challenge to Lead: Maryland

    ERIC Educational Resources Information Center

    Southern Regional Education Board, 2004

    2004-01-01

    The Southern Regional Education Board adopted Challenge to Lead education goals to focus and hold attention on educational improvement in its 16 states. This report provides an overview of Maryland's progress toward meeting these important goals. Challenge to Lead asserts: "With almost half of the new jobs created in America in the 1990s,…

  12. Goals for Education. Challenge to Lead: Arkansas

    ERIC Educational Resources Information Center

    Southern Regional Education Board, 2004

    2004-01-01

    The Southern Regional Education Board adopted Challenge to Lead education goals to focus and hold attention on educational improvement in its 16 states. This report provides an overview of Arkansas' progress toward meeting these important goals. Challenge to Lead asserts: "With almost half of the new jobs created in America in the 1990s, Southern…

  13. Goals for Education. Challenge to Lead: Georgia

    ERIC Educational Resources Information Center

    Southern Regional Education Board, 2004

    2004-01-01

    The Southern Regional Education Board adopted Challenge to Lead education goals to focus and hold attention on educational improvement in its 16 states. This report provides an overview of Georgia's progress toward meeting these important goals. Challenge to Lead asserts: "With almost half of the new jobs created in America in the 1990s, Southern…

  14. Goals for Education. Challenge to Lead: Delaware

    ERIC Educational Resources Information Center

    Southern Regional Education Board, 2004

    2004-01-01

    The Southern Regional Education Board adopted Challenge to Lead education goals to focus and hold attention on educational improvement in its 16 states. This report provides an overview of Delaware's progress toward meeting these important goals. Challenge to Lead asserts: "With almost half of the new jobs created in America in the 1990s,…

  15. Goals for Education. Challenge to Lead: Tennessee

    ERIC Educational Resources Information Center

    Southern Regional Education Board, 2004

    2004-01-01

    The Southern Regional Education Board adopted Challenge to Lead education goals to focus and hold attention on educational improvement in its 16 states. This report provides an overview of Tennessee's progress toward meeting these important goals. Challenge to Lead asserts: "With almost half of the new jobs created in America in the 1990s, SREB…

  16. Goals for Education. Challenge to Lead: Kentucky

    ERIC Educational Resources Information Center

    Southern Regional Education Board, 2004

    2004-01-01

    The Southern Regional Education Board adopted Challenge to Lead education goals to focus and hold attention on educational improvement in its 16 states. This report provides an overview of Kentucky's progress toward meeting these important goals. Challenge to Lead asserts: "With almost half of the new jobs created in America in the 1990s,…

  17. Goals for Education. Challenge to Lead: Alabama

    ERIC Educational Resources Information Center

    Southern Regional Education Board, 2004

    2004-01-01

    The Southern Regional Education Board adopted Challenge to Lead education goals to focus and hold attention on educational improvement in its 16 states. This report provides an overview of Alabama?s progress toward meeting these important goals. Challenge to Lead asserts: ?With almost half of the new jobs created in America in the 1990s, Southern…

  18. Goals for Education. Challenge to Lead: Oklahoma

    ERIC Educational Resources Information Center

    Southern Regional Education Board, 2004

    2004-01-01

    The Southern Regional Education Board adopted Challenge to Lead education goals to focus and hold attention on educational improvement in its 16 states. This report provides an overview of Oklahoma's progress toward meeting these important goals. Challenge to Lead asserts: "With almost half of the new jobs created in America in the 1990s, SREB…

  19. Goals for Education. Challenge to Lead: Florida

    ERIC Educational Resources Information Center

    Southern Regional Education Board, 2004

    2004-01-01

    The Southern Regional Education Board adopted Challenge to Lead education goals to focus and hold attention on educational improvement in its 16 states. This report provides an overview of Florida's progress toward meeting these important goals. Challenge to Lead asserts: "With almost half of the new jobs created in America in the 1990s, Southern…

  20. Goals for Education. Challenge to Lead: Louisiana

    ERIC Educational Resources Information Center

    Southern Regional Education Board, 2004

    2004-01-01

    The Southern Regional Education Board adopted Challenge to Lead education goals to focus and hold attention on educational improvement in its 16 states. This report provides an overview of Louisiana's progress toward meeting these important goals. Challenge to Lead asserts: "With almost half of the new jobs created in America in the 1990s,…

  1. Goals for Education. Challenge to Lead: Texas

    ERIC Educational Resources Information Center

    Southern Regional Education Board, 2004

    2004-01-01

    The Southern Regional Education Board adopted Challenge to Lead education goals to focus and hold attention on educational improvement in its 16 states. This report provides an overview of Texas' progress toward meeting these important goals. Challenge to Lead asserts: "With almost half of the new jobs created in America in the 1990s, SREB states…

  2. Hitting the Moving Target: Challenges of Creating a Dynamic Curriculum Addressing the Ethical Dimensions of Geospatial Data

    ERIC Educational Resources Information Center

    Carr, John; Vallor, Shannon; Freundschuh, Scott; Gannon, William L.; Zandbergen, Paul

    2014-01-01

    While established ethical norms and core legal principles concerning the protection of privacy may be easily identified, applying these standards to rapidly evolving digital information technologies, markets for digital information and convulsive changes in social understandings of privacy is increasingly challenging. This challenge has been…

  3. Moral Injury, Soul Repair, and Creating a Place for Grace

    ERIC Educational Resources Information Center

    Antal, Chris J.; Winings, Kathy

    2015-01-01

    Our returning veterans face many challenges from loss of limb and physical disabilities to posttraumatic stress disorder, depression, substance abuse, homelessness, family problems, and unemployment. The greater challenge, though, for returning veterans is the injury to their soul due to the war and violence they have experienced. Our challenge is…

  4. Spicing up Classrooms Using Creative Challenges

    ERIC Educational Resources Information Center

    Rubenstein, Lisa DaVia; Wilson, Hope E.

    2011-01-01

    Gifted programs have long relied upon creative challenges (activities in which students are asked to create a product or an idea in response to specific teacher directions) to spark ideas, collaboration, and exploration. These challenges, however, have often been devoid of context. Gifted students are pulled out of the classroom to build a bridge…

  5. Geoscience Challenges of a State-by-state Adoption or Adaptation of the NGSS

    NASA Astrophysics Data System (ADS)

    Wysession, M. E.

    2016-12-01

    For the geosciences, the Next Generation Science Standards (NGSS) contain the largest shift in K-12 education to have happened in our lifetimes, but its adoption is playing our very differently in different states. Because it is illegal to have a national curriculum, the NGSS intentionally avoided providing a curriculum but rather a set of performance expectations that each state (or district or school) could use in its own way to construct assessments and curricula. The result is that although more than 80% of schools in the U.S. are in the process of revising their curricula to align with the NGSS, this is happening in a different way in each state (or district or school). Instead of having a single target for curriculum developers to aim for, the result is to actually create a greater diversity of pedagogic platforms across the U.S. schools than there was before the NGSS were released. Some states (Alaska, North Dakota, Texas, Virginia) stated at the outset that they would not be adopting any version of the NGSS at all. So far seventeen states (and D.C.) have adopted the NGSS verbatim, but they are still each developing their curricula in their own way. In fossil-fuel-concentrated communities, such as Wyoming, Oklahoma, and West Virginia, the strong presence of the topics of climate and climate change in the NGSS have created complications for its adoption. States that still only require two years of high school science for all students, so the addition of a year of Earth and Space Science is creating legislative challenges. There is a general lack of trained and accredited high school geoscience teachers in nearly all states (with a few notable exceptions, such as New York), so the preparation and training of high school geoscience teachers is a significant nationwide concern. There are also large variations in the development of assessment materials, pre-service training, and updating certification programs. Progress is definitely being made, but the NGSS is looking like a patchwork quilt, with no two states' pieces the same, and this is posing great challenges for curriculum developers.

  6. Cognitive behavioral game design: a unified model for designing serious games

    PubMed Central

    Starks, Katryna

    2014-01-01

    Video games have a unique ability to engage, challenge, and motivate, which has led teachers, psychology specialists, political activists and health educators to find ways of using them to help people learn, grow and change. Serious games, as they are called, are defined as games that have a primary purpose other than entertainment. However, it is challenging to create games that both educate and entertain. While game designers have embraced some psychological concepts such as flow and mastery, understanding how these concepts work together within established psychological theory would assist them in creating effective serious games. Similarly, game design professionals have understood the propensity of video games to teach while lamenting that educators do not understand how to incorporate educational principles into game play in a way that preserves the entertainment. Bandura (2006) social cognitive theory (SCT) has been used successfully to create video games that create positive behavior outcomes, and teachers have successfully used Gardner’s (1983) theory of multiple intelligences (MIs) to create engaging, immersive learning experiences. Cognitive behavioral game design is a new framework that incorporates SCT and MI with game design principles to create a game design blueprint for serious games. PMID:24550858

  7. Cognitive behavioral game design: a unified model for designing serious games.

    PubMed

    Starks, Katryna

    2014-01-01

    Video games have a unique ability to engage, challenge, and motivate, which has led teachers, psychology specialists, political activists and health educators to find ways of using them to help people learn, grow and change. Serious games, as they are called, are defined as games that have a primary purpose other than entertainment. However, it is challenging to create games that both educate and entertain. While game designers have embraced some psychological concepts such as flow and mastery, understanding how these concepts work together within established psychological theory would assist them in creating effective serious games. Similarly, game design professionals have understood the propensity of video games to teach while lamenting that educators do not understand how to incorporate educational principles into game play in a way that preserves the entertainment. Bandura (2006) social cognitive theory (SCT) has been used successfully to create video games that create positive behavior outcomes, and teachers have successfully used Gardner's (1983) theory of multiple intelligences (MIs) to create engaging, immersive learning experiences. Cognitive behavioral game design is a new framework that incorporates SCT and MI with game design principles to create a game design blueprint for serious games.

  8. Examining Challenges Related to the Production of Actionable Climate Knowledge for Adaptation Decision-Making: A Focus on Climate Knowledge System Producers

    NASA Astrophysics Data System (ADS)

    Ernst, K.; Preston, B. L.; Tenggren, S.; Klein, R.; Gerger-Swartling, Å.

    2017-12-01

    Many challenges to adaptation decision-making and action have been identified across peer-reviewed and gray literature. These challenges have primarily focused on the use of climate knowledge for adaptation decision-making, the process of adaptation decision-making, and the needs of the decision-maker. Studies on climate change knowledge systems often discuss the imperative role of climate knowledge producers in adaptation decision-making processes and stress the need for producers to engage in knowledge co-production activities and to more effectively meet decision-maker needs. While the influence of climate knowledge producers on the co-production of science for adaptation decision-making is well-recognized, hardly any research has taken a direct approach to analyzing the challenges that climate knowledge producers face when undertaking science co-production. Those challenges can influence the process of knowledge production and may hinder the creation, utilization, and dissemination of actionable knowledge for adaptation decision-making. This study involves semi-structured interviews, focus groups, and participant observations to analyze, identify, and contextualize the challenges that climate knowledge producers in Sweden face as they endeavor to create effective climate knowledge systems for multiple contexts, scales, and levels across the European Union. Preliminary findings identify complex challenges related to education, training, and support; motivation, willingness, and culture; varying levels of prioritization; professional roles and responsibilities; the type and amount of resources available; and professional incentive structures. These challenges exist at varying scales and levels across individuals, organizations, networks, institutions, and disciplines. This study suggests that the creation of actionable knowledge for adaptation decision-making is not supported across scales and levels in the climate knowledge production landscape. Additionally, enabling the production of actionable knowledge for adaptation decision-making requires multi-level effort beyond the individual level.

  9. Improving Pedestrian Access to Transit: City of Gresham's Ped-to-MAX Program

    DOT National Transportation Integrated Search

    1999-01-01

    Accommodating multi-modal travel on high speed arterials is a challenge, : particularly in Gresham where numerous arterials transect the city, creating : barriers to pedestrians, bicyclists, and transit users. The "Ped-to-MAX" : program was created t...

  10. Assessment "Honest Alternatives".

    ERIC Educational Resources Information Center

    Mandel, Susan Glazer

    1995-01-01

    Addresses the challenge of finding or creating alternatives to tests and traditional grading systems. Reflects on and describes the experience of creating an assessment tool and cautions against choosing alternatives that merely camouflage the grades. Encourages educators to find authentic alternatives to describe children's growth. (BAC)

  11. Challenges and benefits of conducting environmental justice research in a school setting.

    PubMed

    Guidry, Virginia T; Lowman, Amy; Hall, Devon; Baron, Dothula; Wing, Steve

    2014-01-01

    Environmental justice (EJ) research requires attention to consequences for research participants beyond those typically considered by institutional review boards. The imbalance of power between impacted communities and those who create and regulate pollution creates challenges for participation, yet research can also benefit those involved. Our community-academic partnership designed the Rural Air Pollutants and Children's Health (RAPCH) study to provide positive impacts while measuring health effects at three low-resource public middle schools near concentrated animal feeding operations (CAFOs) in North Carolina. We evaluated perceived benefits and challenges of study involvement by interviewing school staff and community liaisons who facilitated data collection. Reported benefits included enhancement of students' academic environment and increased community environmental awareness; challenges were associated mainly with some participants' immaturity. Leadership from a strong community-based organization was crucial to recruitment, yet our approach entailed minimal focus on EJ, which may have limited opportunities for community education or organizing for environmental health.

  12. A Case Study: Using Delmia at Kennedy Space Center to Support NASA's Constellation Program

    NASA Technical Reports Server (NTRS)

    Kickbusch, Tracey; Humeniuk, Bob

    2010-01-01

    The presentation examines the use of Delmia (Digital Enterprise Lean Manufacturing Interactive Application) for digital simulation in NASA's Constellation Program. Topics include an overview of the Kennedy Space Center (KSC) Design Visualization Group tasks, NASA's Constellation Program, Ares 1 ground processing preliminary design review, and challenges and how Delmia is used at KSC, Challenges include dealing with large data sets, creating and maintaining KSC's infrastructure, gathering customer requirements and meeting objectives, creating life-like simulations, and providing quick turn-around on varied products,

  13. Complexities in Subsetting Satellite Level 2 Data

    NASA Astrophysics Data System (ADS)

    Huwe, P.; Wei, J.; Albayrak, A.; Silberstein, D. S.; Alfred, J.; Savtchenko, A. K.; Johnson, J. E.; Hearty, T.; Meyer, D. J.

    2017-12-01

    Satellite Level 2 data presents unique challenges for tools and services. From nonlinear spatial geometry to inhomogeneous file data structure to inconsistent temporal variables to complex data variable dimensionality to multiple file formats, there are many difficulties in creating general tools for Level 2 data support. At NASA Goddard Earth Sciences Data and Information Services Center (GES DISC), we are implementing a general Level 2 Subsetting service for Level 2 data. In this presentation, we will unravel some of the challenges faced in creating this service and the strategies we used to surmount them.

  14. Creating a meaningful infection control program: one home healthcare agency's lessons.

    PubMed

    Poff, Renee McCoy; Browning, Sarah Via

    2014-03-01

    Creating a meaningful infection control program in the home care setting proved to be challenging for agency leaders of one hospital-based home healthcare agency. Challenges arose when agency leaders provided infection control (IC) data to the hospital's IC Committee. The IC Section Chief asked for national benchmark comparisons to align home healthcare reporting to that of the hospital level. At that point, it was evident that the home healthcare IC program lacked definition and structure. The purpose of this article is to share how one agency built a meaningful IC program.

  15. Tailorable Surface Morphology of 3D Scaffolds by Combining Additive Manufacturing with Thermally Induced Phase Separation.

    PubMed

    Di Luca, Andrea; de Wijn, Joost R; van Blitterswijk, Clemens A; Camarero-Espinosa, Sandra; Moroni, Lorenzo

    2017-08-01

    The functionalization of biomaterials substrates used for cell culture is gearing towards an increasing control over cell activity. Although a number of biomaterials have been successfully modified by different strategies to display tailored physical and chemical surface properties, it is still challenging to step from 2D substrates to 3D scaffolds with instructive surface properties for cell culture and tissue regeneration. In this study, additive manufacturing and thermally induced phase separation are combined to create 3D scaffolds with tunable surface morphology from polymer gels. Surface features vary depending on the gel concentration, the exchanging temperature, and the nonsolvent used. When preosteoblasts (MC-3T3 cells) are cultured on these scaffolds, a significant increase in alkaline phosphatase activity is measured for submicron surface topography, suggesting a potential role on early cell differentiation. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  16. Prospects of application of additive technologies for increasing the efficiency of impeller machines

    NASA Astrophysics Data System (ADS)

    Belova, O. V.; Borisov, Yu. A.

    2017-08-01

    Impeller machine is a device in which the flow path carries out the supply (or retraction) of mechanical energy to the flow of a working fluid passing through the machine. To increase the efficiency of impeller machines, it is necessary to use design modern technologies, namely the use of numerical methods for conducting research in the field of gas dynamics, as well as additive manufacturing (AM) for the of both prototypes and production model. AM technologies are deservedly rightly called revolutionary because they give unique possibility for manufacturing products, creating perfect forms, both light and durable. The designers face the challenge of developing a new design methodology, since AM allows the use of the concept of "Complexity For Free". The "Complexity For Free" conception is based on: complexity of the form; hierarchical complexity; complexity of the material; functional complexity. The new technical items design method according to a functional principle is also investigated.

  17. Edible packaging materials.

    PubMed

    Janjarasskul, Theeranun; Krochta, John M

    2010-01-01

    Research groups and the food and pharmaceutical industries recognize edible packaging as a useful alternative or addition to conventional packaging to reduce waste and to create novel applications for improving product stability, quality, safety, variety, and convenience for consumers. Recent studies have explored the ability of biopolymer-based food packaging materials to carry and control-release active compounds. As diverse edible packaging materials derived from various by-products or waste from food industry are being developed, the dry thermoplastic process is advancing rapidly as a feasible commercial edible packaging manufacturing process. The employment of nanocomposite concepts to edible packaging materials promises to improve barrier and mechanical properties and facilitate effective incorporation of bioactive ingredients and other designed functions. In addition to the need for a more fundamental understanding to enable design to desired specifications, edible packaging has to overcome challenges such as regulatory requirements, consumer acceptance, and scaling-up research concepts to commercial applications.

  18. Hittability: The Leader's Edge.

    PubMed

    Souba, Wiley

    2017-04-01

    Mastery of any discipline entails both the requisite skills and the ability to see things as "hittable." However, the concept of "hittability," which, in the context of leadership, refers to whether or not a specific leadership challenge shows up as hittable (or solvable) for those who are responsible for taking it on, is consistently overlooked. Nevertheless, it is a critical determinant of leadership effectiveness. Hittability is a function of the framing lenses-a person's beliefs, values, and worldviews-which frame the way a person "sees" a leadership challenge. Additionally, the future a person is "living into" is the framing lens for the present. In other words, a person's view of the future shapes his or her view of the present and his or her actions within it. Because the beliefs, values, and worldviews that constitute our framing lenses are constituted in and accessible through language (i.e., in the day-to-day stories, or narratives, a person tells him- or herself), reframing them to create a new future requires a new narrative. The ability to shift the previously unhittable to the hittable won't be, primarily, due to some newly acquired knowledge. Rather, it will be the result of reframing our challenges so they show up as hittable.

  19. Composites

    NASA Astrophysics Data System (ADS)

    Taylor, John G.

    The Composites market is arguably the most challenging and profitable market for phenolic resins aside from electronics. The variety of products and processes encountered creates the challenges, and the demand for high performance in critical operations brings value. Phenolic composite materials are rendered into a wide range of components to supply a diverse and fragmented commercial base that includes customers in aerospace (Space Shuttle), aircraft (interiors and brakes), mass transit (interiors), defense (blast protection), marine, mine ducting, off-shore (ducts and grating) and infrastructure (architectural) to name a few. For example, phenolic resin is a critical adhesive in the manufacture of honeycomb sandwich panels. Various solvent and water based resins are described along with resin characteristics and the role of metal ions for enhanced thermal stability of the resin used to coat the honeycomb. Featured new developments include pultrusion of phenolic grating, success in RTM/VARTM fabricated parts, new ballistic developments for military vehicles and high char yield carbon-carbon composites along with many others. Additionally, global regional market resin volumes and sales are presented and compared with other thermosetting resin systems.

  20. New Insights into Perfluorinated Sulfonic-Acid Ionomers

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kusoglu, Ahmet; Weber, Adam Z.

    In this comprehensive review, recent progress and developments on perfluorinated sulfonic-acid (PFSA) membranes have been summarized on many key topics. Although quite well investigated for decades, PFSA ionomers’ complex behavior, along with their key role in many emerging technologies, have presented significant scientific challenges but also helped create a unique cross-disciplinary research field to overcome such challenges. Research and progress on PFSAs, especially when considered with their applications, are at the forefront of bridging electrochemistry and polymer (physics), which have also opened up development of state-of-the-art in situ characterization techniques as well as multiphysics computation models. Topics reviewed stem frommore » correlating the various physical (e.g., mechanical) and transport properties with morphology and structure across time and length scales. In addition, topics of recent interest such as structure/transport correlations and modeling, composite PFSA membranes, degradation phenomena, and PFSA thin films are presented. Throughout, the impact of PFSA chemistry and side-chain is also discussed to present a broader perspective.« less

  1. Design colloidal particle morphology and self-assembly for coating applications

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Jiang, Shan; Van Dyk, Antony; Maurice, Alvin

    The progressive replacement of organic solvent-based coatings by waterborne latex polymer coatings has substantially renovated the coating industry, and generated huge environmental and health benefits. Today, on top of the continuing demand for higher performance and lower costs, the coating industry faces tighter regulation and higher sustainability standards. In addition, the new waterborne coatings have created unique opportunities and challenges in terms of fundamental understanding and research development. To address these challenges, polymer latex binders with diverse particle morphologies have been developed to improve coating performance. Furthermore, colloidal self-assembly has been utilized to help manufacturers make better paint with lessmore » cost. In this report, we review the recent progress in both fundamental study and industrial application in the context of developing new generation architectural coating materials. We introduce the basic concepts in coating materials and showcase several key technologies that have been implemented to improve coating performance. As a result, these technologies also represent the most important considerations in architectural coating design.« less

  2. Designing the future: NBIC technologies and human performance enhancement.

    PubMed

    Canton, James

    2004-05-01

    Never before has any civilization had the unique opportunity to enhance human performance on the scale that we will face in the near future. The convergence of nanotechnology, biotechnology, information technology, and cognitive science (NBIC) is creating a set of powerful tools that have the potential to significantly enhance human performance as well as transform society, science, economics, and human evolution. As the NBIC convergence becomes more understood, the possibility that we may be able to enhance human performance in the three domains of therapy, augmentation, and designed evolution will become anticipated and even expected. In addition, NBIC convergence represents entirely new challenges for scientists, policymakers, and business leaders who will have, for the first time, vast new and powerful tools to shape markets, societies, and lifestyles. The emergence of NBIC convergence will challenge us in new ways to balance risk and return, threat and opportunity, and social responsibility and competitive advantage as we step into the 21st century.

  3. The James Webb STEM Innovation Project: Bringing JWST to the Education Community

    NASA Astrophysics Data System (ADS)

    Eisenhamer, Bonnie; Harris, J.; Ryer, H.; Taylor, J.; Bishop, M.

    2012-01-01

    Building awareness of a NASA mission prior to launch and connecting that mission to the education community can be challenging. In order to address this challenge, the Space Telescope Science Institute's Office of Public Outreach has developed the James Webb STEM innovation Project (SIP) - an interdisciplinary project that focuses on the engineering aspects and potential scientific discoveries of JWST, while incorporating elements of project-based learning. Students in participating schools will use skills from multiple subject areas to research an aspect of the JWST's design or potential science and create models, illustrated essays, or technology-based projects to demonstrate their learning. Student projects will be showcased during special events at select venues in the project states - thus allowing parents and community members to also be benefactors of the project. Currently, the SIP is being piloted in New York, California, and Maryland. In addition, we will be implementing the SIP in partnership with NASA Explorer Schools in the states of New Mexico, Michigan, Texas, Tennessee, and Iowa.

  4. Exploiting the unique regenerative capacity of the liver to underpin cell and gene therapy strategies for genetic and acquired liver disease.

    PubMed

    Logan, Grant J; de Alencastro, Gustavo; Alexander, Ian E; Yeoh, George C

    2014-11-01

    The number of genetic or acquired diseases of the liver treatable by organ transplantation is ever-increasing as transplantation techniques improve placing additional demands on an already limited organ supply. While cell and gene therapies are distinctly different modalities, they offer a synergistic alternative to organ transplant due to distinct architectural and physiological properties of the liver. The hepatic blood supply and fenestrated endothelial system affords relatively facile accessibility for cell and/or gene delivery. More importantly, however, the remarkable capacity of hepatocytes to proliferate and repopulate the liver creates opportunities for new treatments based on emerging technologies. This review will summarise current understanding of liver regeneration, describe clinical and experimental cell and gene therapeutic modalities and discuss critical challenges to translate these new technologies to wider clinical utility. This article is part of a Directed Issue entitled: "Regenerative Medicine: the challenge of translation". Copyright © 2014 Elsevier Ltd. All rights reserved.

  5. Design Recommendations for Pharmacogenomics Clinical Decision Support Systems

    PubMed Central

    Khelifi, Maher; Tarczy-Hornoch, Peter; Devine, Emily B.; Pratt, Wanda

    2017-01-01

    The use of pharmacogenomics (PGx) in clinical practice still faces challenges to fully adopt genetic information in targeting drug therapy. To incorporate genetics into clinical practice, many support the use of Pharmacogenomics Clinical Decision Support Systems (PGx-CDS) for medication prescriptions. This support was fueled by new guidelines to incorporate genetics for optimizing drug dosage and reducing adverse events. In addition, the complexity of PGx led to exploring CDS outside the paradigm of the basic CDS tools embedded in commercial electronic health records. Therefore, designing the right CDS is key to unleashing the full potential of pharmacogenomics and making it a part of clinicians’ daily workflow. In this work, we 1) identify challenges and barriers of the implementation of PGx-CDS in clinical settings, 2) develop a new design approach to CDS with functional characteristics that can improve the adoption of pharmacogenomics guidelines and thus patient safety, and 3) create design guidelines and recommendations for such PGx-CDS tools. PMID:28815136

  6. Design colloidal particle morphology and self-assembly for coating applications

    DOE PAGES

    Jiang, Shan; Van Dyk, Antony; Maurice, Alvin; ...

    2017-05-04

    The progressive replacement of organic solvent-based coatings by waterborne latex polymer coatings has substantially renovated the coating industry, and generated huge environmental and health benefits. Today, on top of the continuing demand for higher performance and lower costs, the coating industry faces tighter regulation and higher sustainability standards. In addition, the new waterborne coatings have created unique opportunities and challenges in terms of fundamental understanding and research development. To address these challenges, polymer latex binders with diverse particle morphologies have been developed to improve coating performance. Furthermore, colloidal self-assembly has been utilized to help manufacturers make better paint with lessmore » cost. In this report, we review the recent progress in both fundamental study and industrial application in the context of developing new generation architectural coating materials. We introduce the basic concepts in coating materials and showcase several key technologies that have been implemented to improve coating performance. As a result, these technologies also represent the most important considerations in architectural coating design.« less

  7. Regulatory Considerations in the Design and Manufacturing of Implantable 3D‐Printed Medical Devices

    PubMed Central

    Morrison, Robert J.; Kashlan, Khaled N.; Flanangan, Colleen L.; Wright, Jeanne K.; Green, Glenn E.; Hollister, Scott J.

    2015-01-01

    Abstract Three‐dimensional (3D) printing, or additive manufacturing, technology has rapidly penetrated the medical device industry over the past several years, and innovative groups have harnessed it to create devices with unique composition, structure, and customizability. These distinctive capabilities afforded by 3D printing have introduced new regulatory challenges. The customizability of 3D‐printed devices introduces new complexities when drafting a design control model for FDA consideration of market approval. The customizability and unique build processes of 3D‐printed medical devices pose unique challenges in meeting regulatory standards related to the manufacturing quality assurance. Consistent material powder properties and optimal printing parameters such as build orientation and laser power must be addressed and communicated to the FDA to ensure a quality build. Postprinting considerations unique to 3D‐printed devices, such as cleaning, finishing and sterilization are also discussed. In this manuscript we illustrate how such regulatory hurdles can be navigated by discussing our experience with our group's 3D‐printed bioresorbable implantable device. PMID:26243449

  8. New Insights into Perfluorinated Sulfonic-Acid Ionomers

    DOE PAGES

    Kusoglu, Ahmet; Weber, Adam Z.

    2017-01-23

    In this comprehensive review, recent progress and developments on perfluorinated sulfonic-acid (PFSA) membranes have been summarized on many key topics. Although quite well investigated for decades, PFSA ionomers’ complex behavior, along with their key role in many emerging technologies, have presented significant scientific challenges but also helped create a unique cross-disciplinary research field to overcome such challenges. Research and progress on PFSAs, especially when considered with their applications, are at the forefront of bridging electrochemistry and polymer (physics), which have also opened up development of state-of-the-art in situ characterization techniques as well as multiphysics computation models. Topics reviewed stem frommore » correlating the various physical (e.g., mechanical) and transport properties with morphology and structure across time and length scales. In addition, topics of recent interest such as structure/transport correlations and modeling, composite PFSA membranes, degradation phenomena, and PFSA thin films are presented. Throughout, the impact of PFSA chemistry and side-chain is also discussed to present a broader perspective.« less

  9. The 21st Century Challenges and the Food-Energy-Water-Security (FEWS) Nexus in the Middle East Region

    NASA Astrophysics Data System (ADS)

    Moradkhani, H.; Hameed, M.

    2017-12-01

    Developing countries have experienced crucial conditions in meeting the needs for food, energy, and water security. This paper presents a country-level quantitative assessment of the current issues associated with the Food-Energy-Water-Security (FEWS) Nexus in the Middle East region. In this study, sixteen countries in the Middle East region are chosen, namely, Arabian Peninsula, Iran, Syria, Lebanon, Israel, Palestine, Egypt, and Turkey. The most recent datasets are used to study and analyze the factors that have emerged the demand to understand and manage the linkage of FEW systems in the region. Water scarcity, extreme events, population growth, urbanization, economic growth, poverty, and political stability are found to be the key drivers of the current challenges in the Middle East region. Additionally, the results suggest that these factors have created a subsequent stress on FEW resources specifically on water sector in the region. Therefore, more attention is required to sustain the FEW resources and cope with the socio-economic development.

  10. Design and Lessons Learned on the Development of a Cryogenic Pupil Select Mechanism (PSM)

    NASA Technical Reports Server (NTRS)

    Mitchell, Alissa L.; Capon, Thomas L.; Hakun, Claef; Haney, Paul; Koca, Corina; Guzek, Jeffrey

    2014-01-01

    Calibration and testing of the instruments on the Integrated Science Instrument Module (ISIM) of the James Webb Space Telescope (JWST) is being performed by the use of a cryogenic, full-field, optical simulator that was constructed for this purpose. The Pupil Select Mechanism (PSM) assembly is one of several mechanisms and optical elements that compose the Optical Telescope Element SIMulator, or OSIM. The PSM allows for several optical elements to be inserted into the optical plane of OSIM, introducing a variety of aberrations, distortions, obscurations, and other calibration states into the pupil plane. The following discussion focuses on the details of the design evolution, analysis, build, and test of this mechanism along with the challenges associated with creating a sub arc-minute positioning mechanism operating in an extreme cryogenic environment. In addition, difficult challenges in the control system design will be discussed including the incorporation of closed-loop feedback control into a system that was designed to operate in an open-loop fashion.

  11. Additional self-monitoring tools in the dietary modification component of The Women's Health Initiative.

    PubMed

    Mossavar-Rahmani, Yasmin; Henry, Holly; Rodabough, Rebecca; Bragg, Charlotte; Brewer, Amy; Freed, Trish; Kinzel, Laura; Pedersen, Margaret; Soule, C Oehme; Vosburg, Shirley

    2004-01-01

    Self-monitoring promotes behavior changes by promoting awareness of eating habits and creates self-efficacy. It is an important component of the Women's Health Initiative dietary intervention. During the first year of intervention, 74% of the total sample of 19,542 dietary intervention participants self-monitored. As the study progressed the self-monitoring rate declined to 59% by spring 2000. Participants were challenged by inability to accurately estimate fat content of restaurant foods and the inconvenience of carrying bulky self-monitoring tools. In 1996, a Self-Monitoring Working Group was organized to develop additional self-monitoring options that were responsive to participant needs. This article describes the original and additional self-monitoring tools and trends in tool use over time. Original tools were the Food Diary and Fat Scan. Additional tools include the Keeping Track of Goals, Quick Scan, Picture Tracker, and Eating Pattern Changes instruments. The additional tools were used by the majority of participants (5,353 of 10,260 or 52% of participants who were self-monitoring) by spring 2000. Developing self-monitoring tools that are responsive to participant needs increases the likelihood that self-monitoring can enhance dietary reporting adherence, especially in long-term clinical trials.

  12. Local Strategies: Creating and Nurturing Collaborative Communities of Practice

    ERIC Educational Resources Information Center

    Bauer, Denise; Beaulieu, Elizabeth; Wobbe, Kristin

    2017-01-01

    Creating meaningful professional development opportunities for general education faculty can be particularly challenging at professionally-focused institutions where teaching liberal arts courses is sometimes viewed merely as a service requirement. Committing to sustained professional development for general education faculty can lead to…

  13. The Opportunities and Challenges of Partnering with Schools

    ERIC Educational Resources Information Center

    Center for Higher Education Policy Analysis, University of Southern California, 2005

    2005-01-01

    While the benefits of partnerships between school and external groups are many (building social capital, enhancing educational reform, creating stronger communities, increasing academic achievements, and enhancing school performance), creating effective partnerships does not always come easily. One of the first decisions that organizations…

  14. Creating and Implementing Practices That Promote and Support Quality Student Affairs Professionals

    ERIC Educational Resources Information Center

    Tyrell, Steve

    2014-01-01

    In this chapter, the author draws on this volume's chapters to identify prominent issues and challenges facing student affairs professionals. Suggestions for practice are provided that support the work of professionals to create quality educational environments.

  15. Remapping Revisionist Historiography

    ERIC Educational Resources Information Center

    Gold, David

    2012-01-01

    Rhetoric and composition historiography has recently undergone a rapid transformation as scholars have complicated and challenged earlier narratives by examining diverse local histories and alternative rhetorical traditions. This revisionist scholarship has in turn created new research challenges, as scholars must now demonstrate connections…

  16. Goals for Education. Challenge to Lead: West Virginia

    ERIC Educational Resources Information Center

    Southern Regional Education Board, 2004

    2004-01-01

    The Southern Regional Education Board adopted Challenge to Lead education goals to focus and hold attention on educational improvement in its 16 states. This report provides an overview of West Virginia's progress toward meeting these important goals. Challenge to Lead asserts: "With almost half of the new jobs created in America in the 1990s,…

  17. Goals for Education. Challenge to Lead: South Carolina

    ERIC Educational Resources Information Center

    Southern Regional Education Board, 2004

    2004-01-01

    The Southern Regional Education Board adopted Challenge to Lead education goals to focus and hold attention on educational improvement in its 16 states. This report provides an overview of South Carolina's progress toward meeting these important goals. Challenge to Lead asserts: "With almost half of the new jobs created in America in the 1990s,…

  18. Goals for Education. Challenge to Lead: North Carolina

    ERIC Educational Resources Information Center

    Southern Regional Education Board, 2004

    2004-01-01

    The Southern Regional Education Board adopted Challenge to Lead education goals to focus and hold attention on educational improvement in its 16 states. This report provides an overview of North Carolina's progress toward meeting these important goals. Challenge to Lead asserts: "With almost half of the new jobs created in America in the 1990s,…

  19. Lifelong Learning in Challenging Times

    ERIC Educational Resources Information Center

    Thomson, Alastair

    2010-01-01

    In the wake of the general election, the new government--and the United Kingdom--face a range of pressing challenges. In this article, the author sets out what he believes to be the principal challenges and calls for action to create a learning society. The agenda set out would, if followed by the new government, pave the way to a genuine learning…

  20. Creating Publications: Write To Fight Crime. Youth in Action Bulletin, Number 16.

    ERIC Educational Resources Information Center

    Department of Justice, Washington, DC. Office of Justice Programs.

    Publications, which can be anything from a one-page flier to a brochure to a poster or a book, can be relatively easy to create but very effective for helping to fight crime. This bulletin considers how publications can contribute to crime prevention; what it takes to start a publication; what are some of the challenges in creating a publication;…

  1. A Cyberspace Command and Control Model (Maxwell Paper, Number 47)

    DTIC Science & Technology

    2009-08-01

    mand [for] Network Warfare [JFCC-NW]).ŗ This arrange- ment further creates gaps and seams as the DOD attempts, through a traditional, hierarchical...pervasiveness of cyberspace coupled with aggressive adversaries create a volatile environment. The DOD. along with the rest of the world, is...these factors, along with the challenges of attributing cyberspace intrusions, combine to create an environment of frustrating ambiguity. The correct

  2. Optimal medical outcomes with limited liability: risk management principles for medical practices at the intersection of medicine, law, and business.

    PubMed

    Paterick, Timothy J; Paterick, Timothy E; Waterhouse, Blake E

    2007-01-01

    Physicians practice at the intersection of medicine, law, and business. Each discipline creates its own challenges for the practicing physician: to practice efficient, effective medicine; to limit potential liability; and to create a positive financial outcome. Those challenges increase with escalating costs and reduced reimbursements. In this paper, the common clinical presentation of chest pain has been used to create a paradigm to educate physicians to understand efficient and effective approaches to diagnosis and treatment, and how effective communication with patients and meticulous documentation of all medical encounters can limit the potential for liability. Ultimately, given today's reimbursement formulas, physicians must also understand the cost of testing, in relation to its benefits, in an attempt to yield a positive financial outcome.

  3. Creating a public space and dialogue on sexuality and rights: a case study from Bangladesh.

    PubMed

    Rashid, Sabina Faiz; Standing, Hilary; Mohiuddin, Mahrukh; Ahmed, Farah Mahjabeen

    2011-06-16

    This article describes and analyses a research based engagement by a university school of public health in Bangladesh aimed at raising public debate on sexuality and rights and making issues such as discrimination more visible to policy makers and other key stakeholders in a challenging context. The impetus for this work came from participation in an international research programme with a particular interest in bridging international and local understandings of sexual and reproductive rights. The research team worked to create a platform to broaden discussions on sexuality and rights by building on a number of research activities on rural and urban men's and women's sexual health concerns, and on changing concepts of sexuality and understandings of sexual rights among specific population groups in Dhaka city, including sexual minorities. Linked to this on-going process of improving the evidence base, there has been a series of learning and capacity building activities over the last four years consisting of training workshops, meetings, conferences and dialogues. These brought together different configurations of stakeholders - members of sexual minorities, academics, service providers, advocacy organisations, media and policy makers. This process contributed to developing more effective advocacy strategies through challenging representations of sexuality and rights in the public domain. Gradually, these efforts brought visibility to hidden or stigmatised sexuality and rights issues through interim outcomes that have created important steps towards changing attitudes and policies. These included creating safe spaces for sexual minorities to meet and strategise, development of learning materials for university students and engagement with legal rights groups on sexual rights. Through this process, it was found to be possible to create a public space and dialogue on sexuality and rights in a conservative and challenging environment like Bangladesh by bringing together a diverse group of stakeholders to successfully challenge representations of sexuality in the public arena. A further challenge for BRAC University has been to assess its role as a teaching and research organisation, and find a balance between the two roles of research and activism in doing work on sexuality issues in a very sensitive political context.

  4. Development of elastomeric flight muscles for flapping wing micro air vehicles

    NASA Astrophysics Data System (ADS)

    Lau, Gih-Keong; Chin, Yao-Wei; La, Thanh-Giang

    2017-04-01

    Common drivers of flapping wings are a motorized crank mechanisms, which convert the motor rotation into wing reciprocation. Energetic efficiency of the motorized wing flappers can be quite low due to the lack of elastic storage and high friction. This paper relook into the flapping flight apparatus of natural flyers and draw inspiration to develop flight muscles capable of elastic storage, in addition to the frictionless thoracic compliant mechanisms. We review the recent findings on the use of dielectric elastomer actuators as flight muscles. We also discuss the challenges and the prospects of using dielectric elastomer minimum energy structure to create large and fast bending/unbending, possibly for wing flapping.

  5. Formation of nanoporous Si upon self-organized growth of Al and Si nanostructures.

    PubMed

    Thøgersen, Annett; Jensen, Ingvild J T; Stange, Marit; Kjeldstad, Torunn; Martinez-Martinez, Diego; Løvvik, Ole Martin; Ulyashin, Alexander G; Diplas, Spyros

    2018-08-03

    Nanostructured materials offer unique electronic and optical properties compared to their bulk counterparts. The challenging part of the synthesis is to create a balance between the control of design, size limitations, up-scalability and contamination. In this work we show that self-organized Al nanowires in amorphous Si can be produced at room temperature by magnetron co-sputtering using two individual targets. Nanoporous Si, containing nanotunnels with dimensions within the quantum confinement regime, were then made by selective etching of Al. The material properties, film growth, and composition of the films were investigated for different compositions. In addition, the reflectance of the etched film has been measured.

  6. Nurse leader resilience: career defining moments.

    PubMed

    Cline, Susan

    2015-01-01

    Resilience is an essential component of effective nursing leadership. It is defined as the ability to survive and thrive in the face of adversity. Resilience can be developed and internalized as a measure to improve retention and reduce burnout. Nurse leaders at all levels should develop these competencies to survive and thrive in an increasingly complex health care environment. Building positive relationships, maintaining positivity, developing emotional insight, creating work-life balance, and reflecting on successes and challenges are effective strategies for resilience building. Nurse leaders have a professional obligation to develop resilience in themselves, the teams they supervise, and the organization as a whole. Additional benefits include reduced turnover, reduced cost, and improved quality outcomes through organizational mindfulness.

  7. Enhancing the platinum atomic layer deposition infiltration depth inside anodic alumina nanoporous membrane

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Vaish, Amit, E-mail: anv@udel.edu; Krueger, Susan; Dimitriou, Michael

    Nanoporous platinum membranes can be straightforwardly fabricated by forming a Pt coating inside the nanopores of anodic alumina membranes (AAO) using atomic layer deposition (ALD). However, the high-aspect-ratio of AAO makes Pt ALD very challenging. By tuning the process deposition temperature and precursor exposure time, enhanced infiltration depth along with conformal coating was achieved for Pt ALD inside the AAO templates. Cross-sectional scanning electron microscopy/energy dispersive x-ray spectroscopy and small angle neutron scattering were employed to analyze the Pt coverage and thickness inside the AAO nanopores. Additionally, one application of platinum-coated membrane was demonstrated by creating a high-density protein-functionalized interface.

  8. Ciência & Saúde coletiva Journal at the national and international context of scientific communication.

    PubMed

    Minayo, Maria Cecília de Souza; Gomes, Romeu

    2015-07-01

    The article discusses the role of the Ciência & Saúde Coletiva Journal in the dissemination of knowledge in Brazil and in the international scientific community, its new challenges and role in the consolidation of the national public health field. Its history is outlined, positioning it as a scientific journal and the themes approached in it are analyzed. Among the findings, it is emphasized that the journal features a structured space by the habitus of public health, and creates its own habitus that contributes to structure this field. In addition, the journal contributes to the development of critical mass in the area and is committed to the Brazilian Public Health System.

  9. Using information technology to improve the quality and efficiency of clinical trial research in academic medical centers.

    PubMed

    Hardison, C D; Schnetzer, T

    1999-01-01

    In the area of clinical trial research, academic medical centers (AMCs) need to create additional capacity and improve performance on vital indicators to attract more studies, as they are currently losing their share to stand-alone research sites. Through the utilization of information technology, AMCs will be in a better position to fend off the competitive threats to their clinical research dollars. Most AMCs are in an enviable position to leverage the value of information technology because of the existing people, processes, and technologies that probably already exist throughout the AMC. The challenge, then, is to deploy these resources in a different manner to support clinical trial research.

  10. Generating carbon finance through avoided deforestation and its potential to create climatic, conservation and human development benefits.

    PubMed

    Ebeling, Johannes; Yasué, Maï

    2008-05-27

    Recent proposals to compensate developing countries for reducing emissions from deforestation (RED) under forthcoming climate change mitigation regimes are receiving increasing attention. Here we demonstrate that if RED credits were traded on international carbon markets, even moderate decreases in deforestation rates could generate billions of Euros annually for tropical forest conservation. We also discuss the main challenges for a RED mechanism that delivers real climatic benefits. These include providing sufficient incentives while only rewarding deforestation reductions beyond business-as-usual scenarios, addressing risks arising from forest degradation and international leakage, and ensuring permanence of emission reductions. Governance may become a formidable challenge for RED because some countries with the highest RED potentials score poorly on governance indices. In addition to climate mitigation, RED funds could help achieve substantial co-benefits for biodiversity conservation and human development. However, this will probably require targeted additional support because the highest biodiversity threats and human development needs may exist in countries that have limited income potentials from RED. In conclusion, how successfully a market-based RED mechanism can contribute to climate change mitigation, conservation and development will strongly depend on accompanying measures and carefully designed incentive structures involving governments, business, as well as the conservation and development communities.

  11. Cloud-enabled large-scale land surface model simulations with the NASA Land Information System

    NASA Astrophysics Data System (ADS)

    Duffy, D.; Vaughan, G.; Clark, M. P.; Peters-Lidard, C. D.; Nijssen, B.; Nearing, G. S.; Rheingrover, S.; Kumar, S.; Geiger, J. V.

    2017-12-01

    Developed by the Hydrological Sciences Laboratory at NASA Goddard Space Flight Center (GSFC), the Land Information System (LIS) is a high-performance software framework for terrestrial hydrology modeling and data assimilation. LIS provides the ability to integrate satellite and ground-based observational products and advanced modeling algorithms to extract land surface states and fluxes. Through a partnership with the National Center for Atmospheric Research (NCAR) and the University of Washington, the LIS model is currently being extended to include the Structure for Unifying Multiple Modeling Alternatives (SUMMA). With the addition of SUMMA in LIS, meaningful simulations containing a large multi-model ensemble will be enabled and can provide advanced probabilistic continental-domain modeling capabilities at spatial scales relevant for water managers. The resulting LIS/SUMMA application framework is difficult for non-experts to install due to the large amount of dependencies on specific versions of operating systems, libraries, and compilers. This has created a significant barrier to entry for domain scientists that are interested in using the software on their own systems or in the cloud. In addition, the requirement to support multiple run time environments across the LIS community has created a significant burden on the NASA team. To overcome these challenges, LIS/SUMMA has been deployed using Linux containers, which allows for an entire software package along with all dependences to be installed within a working runtime environment, and Kubernetes, which orchestrates the deployment of a cluster of containers. Within a cloud environment, users can now easily create a cluster of virtual machines and run large-scale LIS/SUMMA simulations. Installations that have taken weeks and months can now be performed in minutes of time. This presentation will discuss the steps required to create a cloud-enabled large-scale simulation, present examples of its use, and describe the potential deployment of this information technology with other NASA applications.

  12. Enhancing moist forest restoration opportunities in riparian systems

    Treesearch

    Theresa Benavidez Jain; Russell T. Graham

    2004-01-01

    In northern Rocky Mountain moist forests, riparian systems contain many attributes that create unique biophysical conditions that alter disturbances and microenvironments; thus creating distinct forest structures, species composition, and management challenges. For example, browsing, limited opening size, competition from surrounding ground vegetation, high soil...

  13. Challenging Heteronormativity: Creating a Safe and Inclusive Environment for LGBTQ Students

    ERIC Educational Resources Information Center

    Steck, Andy K.; Perry, David

    2018-01-01

    Lesbian, gay, bisexual, transgender, and queer/questioning (LGBTQ) youth face hostile and exclusionary learning environments. A qualitative phenomenographic method involving semistructured interviews of seven secondary school administrators was conducted to identify perceptions of experiences creating a safe and inclusive environment for students…

  14. Targeted analyte deconvolution and identification by four-way parallel factor analysis using three-dimensional gas chromatography with mass spectrometry data.

    PubMed

    Watson, Nathanial E; Prebihalo, Sarah E; Synovec, Robert E

    2017-08-29

    Comprehensive three-dimensional gas chromatography with time-of-flight mass spectrometry (GC 3 -TOFMS) creates an opportunity to explore a new paradigm in chemometric analysis. Using this newly described instrument and the well understood Parallel Factor Analysis (PARAFAC) model we present one option for utilization of the novel GC 3 -TOFMS data structure. We present a method which builds upon previous work in both GC 3 and targeted analysis using PARAFAC to simplify some of the implementation challenges previously discovered. Conceptualizing the GC 3 -TOFMS instead as a one-dimensional gas chromatograph with GC × GC-TOFMS detection we allow the instrument to create the PARAFAC target window natively. Each first dimension modulation thus creates a full GC × GC-TOFMS chromatogram fully amenable to PARAFAC. A simple mixture of 115 compounds and a diesel sample are interrogated through this methodology. All test analyte targets are successfully identified in both mixtures. In addition, mass spectral matching of the PARAFAC loadings to library spectra yielded results greater than 900 in 40 of 42 test analyte cases. Twenty-nine of these cases produced match values greater than 950. Copyright © 2017 Elsevier B.V. All rights reserved.

  15. Creating student awareness to improve cultural competence: creating the critical incident.

    PubMed

    Morell, Venita W; Sharp, Penny C; Crandall, Sonia J

    2002-09-01

    Teaching medical students to recognize the need for cultural competence and accept their shortcomings in this area is a challenge. A simulated patient scenario was developed to address this challenge. The objective of the simulation is to enhance students' readiness to learn by moving them from 'unconscious incompetence' to 'conscious incompetence'. The patient scenario presents a Cherokee Indian woman with a complaint of abnormal menstrual bleeding who is resistant to gynaecologic care from male providers. A faculty member facilitates a small-group videotape review of student interviews. As students discuss their encounters, they realize they 'misdiagnose' and mishandle the interview. They are confronted by their inability to recognize cultural cues and the impact they may have on health outcomes and begin to question whether cultural beliefs are affecting the care of other patients. This simulation creates an eye-opening situation that must be handled carefully. This activity is an effective method to create awareness in students who feel they 'know all this stuff.'

  16. Will a catch share for whales improve social welfare?

    PubMed

    Smith, Martin D; Asche, Frank; Bennear, Lori S; Havice, Elizabeth; Read, Andrew J; Squires, Dale

    2014-01-01

    We critique a proposal to use catch shares to manage transboundary wildlife resources with potentially high non-extractive values, and we focus on the case of whales. Because whales are impure public goods, a policy that fails to capture all nonmarket benefits (due to free riding) could lead to a suboptimal outcome. Even if free riding were overcome, whale shares would face four implementation challenges. First, a whale share could legitimize the international trade in whale meat and expand the whale meat market. Second, a legal whale trade creates monitoring and enforcement challenges similar to those of organizations that manage highly migratory species such as tuna. Third, a whale share could create a new political economy of management that changes incentives and increases costs for nongovernmental organizations (NGOs) to achieve the current level of conservation. Fourth, a whale share program creates new logistical challenges for quota definition and allocation regardless of whether the market for whale products expands or contracts. Each of these issues, if left unaddressed, could result in lower overall welfare for society than under the status quo.

  17. Project UCARE : Uniform Commuter Assistance Reporting and Evaluation for transportation demand management programs, [summary].

    DOT National Transportation Integrated Search

    2013-09-01

    The federal transportation reauthorization called : Moving Ahead for Progress in the 21st Century Act : (MAP-21) creates a program that addresses many : challenges facing the U.S. transportation system. : These challenges include improving safety, : ...

  18. Cultural Considerations in Counseling Couples Who Experience Infertility

    ERIC Educational Resources Information Center

    Burnett, Judith A.

    2009-01-01

    Infertility creates challenges affecting various aspects of couples' intimate lives. Practices regarding reproduction are often shaped by cultural messages. Culturally sensitive treatment methods help counselors provide effective therapy to couples with fertility problems. This article describes cultural influences, challenges, and counseling…

  19. Travel in adverse winter weather conditions by blind pedestrians.

    DOT National Transportation Integrated Search

    2015-08-31

    Winter weather creates many orientation and mobility (O&M) challenges for people who are visually impaired. Getting the cane tip stuck is one of the noticeable challenges when traveling in snow, particularly when the walking surface is covered in dee...

  20. Connected Building Challenge – Seattle Demonstration

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wang, Nora; Khamphanchai, Warodom; Chotibhongs, Tony

    2016-11-07

    PNNL's first-ever innovation challenge invited teams to leverage PNNL's VOLTTRON technology to create solutions that advance the growth of the smart building market. Five teams presented their solutions at Seattle's Smart Buildings Center in early August 2016. This video summarizes the event.

  1. Emerging Water Contaminants: Technical, Legal and Policy Challenges

    NASA Astrophysics Data System (ADS)

    Deeb, R. A.; Kresic, N.; Laugier, M. C.; Kavanaugh, M. C.

    2002-12-01

    Approximately 120 new chemicals are created each year due to ever-improving industry and technology markets. Releases of new contaminants into the environment can occur during production, use and disposal of these chemicals thereby leading to potential contamination of water supply sources. Very few emerging contaminants are regulated. In addition, knowledge gaps regarding emerging contaminants include lack health effects, occurrence (either because these compounds are not measured or because concentrations are below detection limits of readily available analytical techniques) and fate and transport in the environment especially with regards to mobility and persistence. The sources of these compounds are numerous. One source is treated wastewater, which is re-injected into groundwater aquifers for indirect potable reuse purposes. Emerging compounds of concern can be classified in various classes. This presentation will focus on contaminants, which have emerged in the last 10 years including pharmaceuticals (antibiotics/drugs), personal care products (polycyclic musks), pesticides/herbicides, industrial solvents (1,4-dioxane), gasoline additives (MTBE), disinfection byproducts such as NDMA (N-nitrosodimethylamine), and inorganic compounds such as perchlorate and arsenic. This presentation will present technical, legal and legislative challenges posed by the presence of these contaminants in water. Background information including chemical's history of use, sources in the environments, nationwide occurrence, physical and chemical properties, behavior in the environment and technologies for removal from soil and water will be presented. In addition, case studies on MTBE, pharmaceuticals and personal care products, 1,4-dioxane, arsenic and NDMA will be discussed.

  2. Teamwork & Teamplay: A Guide to Cooperative, Challenge and Adventure Activities That Build Confidence, Cooperation, Teamwork, Creativity, Trust, Decision Making, Conflict Resolution, Resource Management, Communication, Effective Feedback and Problem Solving Skills.

    ERIC Educational Resources Information Center

    Cain, Jim; Jolliff, Barry

    Challenge and adventure programs create situations that challenge the abilities of individuals and groups and that are metaphors for the problems and challenges of daily life. This book describes dozens of group activities that foster individual and group skills such as cooperation, problem solving, and communication. Each activity has a…

  3. Perceived Benefits and Challenges of Coordinated Approaches to Chronic Disease Prevention in State Health Departments

    PubMed Central

    Sequeira, Sonia; Best, Leslie; Jones, Ellen; Baker, Elizabeth A.; Brownson, Ross C.

    2014-01-01

    Introduction Chronic disease prevention efforts have historically been funded categorically according to disease or risk factor. Federal agencies are now progressively starting to fund combined programs to address common risk. The purpose of this study was to inform transitions to coordinated chronic disease prevention by learning views on perceived benefits and challenges of a coordinated approach to funding. Methods A national survey on evidence-based public health was conducted from March through May 2013 among state health department employees working in chronic disease prevention (N = 865). Participants were asked to rank the top 3 benefits and top 3 challenges in coordinating chronic disease approaches from provided lists and could provide additional responses. Descriptive analyses, χ2 tests, and analysis of variance were conducted. Results The most common perceived benefits of coordinated approaches to chronic disease prevention were improved health outcomes, common risk factors better addressed, and reduced duplication of program efforts. The most common perceived challenges were funding restrictions, such as disease-specific performance measures; competing priorities; lack of communication across programs; funding might be reduced; agency not structured for program coordination; and loss of disease-specific partner support. Rankings of benefits and challenges were similar across states and participant roles; the perceived challenges “lack of communication across programs” (P = .02) and “funding might be reduced” differed by program area (P < .001). Conclusion Findings can be used by funding agencies and state health departments for planning, training, and technical assistance. The information on perceived challenges demonstrates the need to improve communication across programs, enhance organizational support for coordinated approaches, and create benefits for organizational partners. PMID:24809362

  4. RCAS: an RNA centric annotation system for transcriptome-wide regions of interest.

    PubMed

    Uyar, Bora; Yusuf, Dilmurat; Wurmus, Ricardo; Rajewsky, Nikolaus; Ohler, Uwe; Akalin, Altuna

    2017-06-02

    In the field of RNA, the technologies for studying the transcriptome have created a tremendous potential for deciphering the puzzles of the RNA biology. Along with the excitement, the unprecedented volume of RNA related omics data is creating great challenges in bioinformatics analyses. Here, we present the RNA Centric Annotation System (RCAS), an R package, which is designed to ease the process of creating gene-centric annotations and analysis for the genomic regions of interest obtained from various RNA-based omics technologies. The design of RCAS is modular, which enables flexible usage and convenient integration with other bioinformatics workflows. RCAS is an R/Bioconductor package but we also created graphical user interfaces including a Galaxy wrapper and a stand-alone web service. The application of RCAS on published datasets shows that RCAS is not only able to reproduce published findings but also helps generate novel knowledge and hypotheses. The meta-gene profiles, gene-centric annotation, motif analysis and gene-set analysis provided by RCAS provide contextual knowledge which is necessary for understanding the functional aspects of different biological events that involve RNAs. In addition, the array of different interfaces and deployment options adds the convenience of use for different levels of users. RCAS is available at http://bioconductor.org/packages/release/bioc/html/RCAS.html and http://rcas.mdc-berlin.de. © The Author(s) 2017. Published by Oxford University Press on behalf of Nucleic Acids Research.

  5. Leaders' perspectives in the Yellowstone to Yukon Conservation Initiative

    USGS Publications Warehouse

    Mattson, D.J.; Clark, S.G.; Byrd, K.L.; Brown, S.R.; Robinson, B.

    2011-01-01

    The Yellowstone to Yukon Conservation Initiative (Y2Y) was created in 1993 to advance conservation in a 1.2 million km2 portion of the North American Rocky Mountains. We assembled 21 people with influence over Y2Y in a workshop to elucidate perspectives on challenges and solutions for this organization at a key point in its evolution, and used Q method to define four perspectives on challenges and three on solutions. Participants were differentiated by four models for effecting change-vision-based advocacy, practice-based learning, political engagement, and scientific management-with emphasis on the first three. Those with authority in Y2Y aligned with vision-based advocacy and expressed ambivalence about practice-based adaptive learning and rigorous appraisals of existing strategies. Workshop results were consistent with an apparent trend toward organizational maturation focused on stabilizing revenues, developing formal organizational arrangements, and focusing strategies. Consolidation of power in Y2Y around a long-standing formula does not bode well for the effectiveness of Y2Y. We recommend that leaders in Y2Y and similar organizations focused on large-scale conservation to create and maintain an open system-philosophically and operationally-that capitalizes on the diverse perspectives and skills of individuals who are attracted to such efforts. We also recommend that the Y2Y initiative be followed closely to harvest additional lessons for potential application to large-scale conservation efforts elsewhere. ?? Springer Science+Business Media, LLC(outside the USA).2011.

  6. Power Watch - A global, open database of power plants that supports research on climate, water and air pollution impact of the global power sector.

    NASA Astrophysics Data System (ADS)

    Friedrich, J.; Kressig, A.; Van Groenou, S.; McCormick, C.

    2017-12-01

    Challenge The lack of transparent, accessible, and centralized power sector data inhibits the ability to research the impact of the global power sector. information gaps for citizens, analysts, and decision makers worldwide create barriers to sustainable development efforts. The need for transparent, accessible, and centralized information is especially important to enhance the commitments outlined in the recently adopted Paris Agreement and Sustainable Development Goals. Offer Power Watch will address this challenge by creating a comprehensive, open-source platform on the world's power systems. The platform hosts data on 85% of global installed electrical capacity and for each power plant will include data points on installed capacity, fuel type, annual generation, commissioning year, with more characteristics like emissions, particulate matter, annual water demand and more added over time. Most of the data is reported from national level sources, but annual generation and other operational characteristiscs are estimated via Machine Learning modeling and remotely sensed data when not officially reported. In addition, Power Watch plans to provide a suite of tools that address specific decision maker needs, such as water risk assessments and air pollution modeling. Impact Through open data, the platform and its tools will allow reserachers to do more analysis of power sector impacts and perform energy modeling. It will help catalyze accountability for policy makers, businesses, and investors and will inform and drive the transition to a clean energy future while reaching development targets.

  7. Pharmaceutical pricing and reimbursement in China: When the whole is less than the sum of its parts.

    PubMed

    Hu, Jia; Mossialos, Elias

    2016-05-01

    In recent years, there has been rapid growth in pharmaceutical spending in China. In addition, the country faces many challenges with regards to the quality, pricing and affordability of drugs. Pricing and reimbursement are important aspects of pharmaceutical policy that must be prioritised in order to address the many challenges. This review draws on multiple sources of information. A review of the academic and grey literature along with official government statistics were combined with information from seminars held by China's State Council Development Research Center to provide an overview of pharmaceutical pricing and reimbursement in China. Pricing and reimbursement policy were analysed through a framework that incorporates supply-side policies, proxy-demand policies and demand-side policies. China's current pharmaceutical policies interact in such a way to create dysfunction in the form of high prices, low drug quality, irrational prescribing and problems with access. Finally, the country's fragmented regulatory environment hampers pharmaceutical policy reform. The pricing and reimbursement policy landscape can be improved through higher drug quality standards, greater market concentration, an increase in government subsidies, quality-oriented tendering, wider implementation of the zero mark-up policy, through linking reimbursement with rational prescribing, and the promotion of health technology assessment and comparative effectiveness research. Addressing broader issues of regulatory fragmentation, the lack of transparency and corruption will help ensure that policies are created in a coherent, evidence-based fashion. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  8. Evaluating local policy adoption campaigns in California: Tobacco Retail License (TRL) adoption.

    PubMed

    Satterlund, Travis D; Treiber, Jeanette; Haun, Sue; Cassady, Diana

    2014-06-01

    As part of its state-wide "denormalization" campaign, the California Tobacco Control Program has funded local tobacco control projects to secure tobacco retail licenses (TRLs) in their communities. TRL policies generate funding by requiring tobacco retailers within a jurisdiction to obtain a license, which is in addition to the state license that tobacco retailers are legally required to purchase to sell tobacco products. The funding provided by TRLs enables local law enforcement to carry out inspection and enforcement operations. This paper examines the unique processes by which local project campaigns attempt to get TRL policies adopted in communities across the State of California. Twenty-two local projects submitted final evaluation reports pertaining to the adoption of TRLs, and the reports from these projects form the basis of the analysis. Successful campaigns tended to include the following strategies: (1) determining policy readiness; (2) gathering local data; (3) identifying and working with a "champion"; (4) building relationships with local law enforcement agencies and decision makers; and (5) educating community and decision makers. The major challenges faced by local projects included budget cuts and staffing issues, concern about creating an unfavorable environment for business by imposing more regulations and fees, and complaints about using law enforcement resources for tobacco control in light of more "pressing" public safety issues. These challenges proved difficult for local projects to overcome, and also highlight the need for projects to create and carry out strong but flexible tactical plans that incorporate the aforementioned strategies.

  9. Sustainability in a Hospital-Based Biobank and University-Based DNA Biorepository: Strategic Roadmaps

    PubMed Central

    Eschbacher, Jennifer; Bowser, Robert; LaBaer, Joshua

    2015-01-01

    Sustainability in the biobanking community has recently become an important and oft-discussed issue as biorepositories struggle to balance limited external funding and complex cost recovery models with high operating costs and the desire to provide the highest quality materials and services to the research community. A multi-faceted view of biobanking sustainability requires consideration of operational and social sustainability in addition to the historical focus exclusively on financial sustainability. Planning and implementing this three pillar model creates a well-rounded biorepository that meets the needs of all the major stakeholders: the funders, the patients/depositors, and the researcher recipients. Often the creation of a detailed business plan is the first step to develop goals and objectives that lead down a path towards sustainability. The definition of sustainability and the complexity of a sustainable business plan may differ for each biorepository. The DNASU Plasmid Repository at Arizona State University stores and distributes DNA plasmids to researchers worldwide, and the Biobank Core Facility at St. Joseph's Hospital and Barrow Neurological Institute consents patients and collects, stores, and distributes human tissue and blood samples. We will discuss these two biorepositories, their similar and different approaches to sustainability and business planning, their challenges in creating and implementing their sustainability plan, and their responses to some of these challenges. From these experiences, the biobanks share lessons learned about planning for sustainability that are applicable to all biorepositories. PMID:26697909

  10. A Method to Represent Heterogeneous Materials for Rapid Prototyping: The Matryoshka Approach.

    PubMed

    Lei, Shuangyan; Frank, Matthew C; Anderson, Donald D; Brown, Thomas D

    The purpose of this paper is to present a new method for representing heterogeneous materials using nested STL shells, based, in particular, on the density distributions of human bones. Nested STL shells, called Matryoshka models, are described, based on their namesake Russian nesting dolls. In this approach, polygonal models, such as STL shells, are "stacked" inside one another to represent different material regions. The Matryoshka model addresses the challenge of representing different densities and different types of bone when reverse engineering from medical images. The Matryoshka model is generated via an iterative process of thresholding the Hounsfield Unit (HU) data using computed tomography (CT), thereby delineating regions of progressively increasing bone density. These nested shells can represent regions starting with the medullary (bone marrow) canal, up through and including the outer surface of the bone. The Matryoshka approach introduced can be used to generate accurate models of heterogeneous materials in an automated fashion, avoiding the challenge of hand-creating an assembly model for input to multi-material additive or subtractive manufacturing. This paper presents a new method for describing heterogeneous materials: in this case, the density distribution in a human bone. The authors show how the Matryoshka model can be used to plan harvesting locations for creating custom rapid allograft bone implants from donor bone. An implementation of a proposed harvesting method is demonstrated, followed by a case study using subtractive rapid prototyping to harvest a bone implant from a human tibia surrogate.

  11. Making sense of the shadows: priorities for creating a learning healthcare system based on routinely collected data

    PubMed Central

    Deeny, Sarah R; Steventon, Adam

    2015-01-01

    Socrates described a group of people chained up inside a cave, who mistook shadows of objects on a wall for reality. This allegory comes to mind when considering ‘routinely collected data’—the massive data sets, generated as part of the routine operation of the modern healthcare service. There is keen interest in routine data and the seemingly comprehensive view of healthcare they offer, and we outline a number of examples in which they were used successfully, including the Birmingham OwnHealth study, in which routine data were used with matched control groups to assess the effect of telephone health coaching on hospital utilisation. Routine data differ from data collected primarily for the purposes of research, and this means that analysts cannot assume that they provide the full or accurate clinical picture, let alone a full description of the health of the population. We show that major methodological challenges in using routine data arise from the difficulty of understanding the gap between patient and their ‘data shadow’. Strategies to overcome this challenge include more extensive data linkage, developing analytical methods and collecting more data on a routine basis, including from the patient while away from the clinic. In addition, creating a learning health system will require greater alignment between the analysis and the decisions that will be taken; between analysts and people interested in quality improvement; and between the analysis undertaken and public attitudes regarding appropriate use of data. PMID:26065466

  12. HUNCH Student Culinary Competition at USSRC's Davidson Center

    NASA Image and Video Library

    2018-02-08

    High Schools United with NASA to Create Hardware (HUNCH) students from 6 schools meet at the U.S. Space and Rocket center in order to participate in the annual culinary challenge where students create meals suitable for astronaut use in space. Students in 2018 created different dishes for breakfast dining. Other NASA centers also participate in this program with the top 10 voted recipes being judged at Johnson Space Center.

  13. Security Challenges in the Gulf of Guinea Sub-Region: Strategy for Nigeria

    DTIC Science & Technology

    2008-06-01

    Gas Fisheries Defense of Shipping Data Sea Power Functioning Ecosystem Nation-States Pollution & Misuse Criminal Activities Poaching ...region, these increased activities have created challenging security issues including increased piracy, poaching , terrorism, militant youth activities... impact its economic, social and political development. Also, the GoG’s vast sea area presents great challenges to the Nigerian nation and the

  14. Including Disabled Children in Learning: Challenges in Developing Countries. CREATE Pathways to Access. Research Monograph No. 36

    ERIC Educational Resources Information Center

    Croft, Alison

    2010-01-01

    This is an exploratory study suggesting ways of analysing challenges for developing countries in the move to greater inclusion of disabled children and young people in learning. The paper focuses on pedagogical challenges to realising more inclusive education. Pedagogy encompasses not only the practice of teaching and learning, but also the ideas…

  15. London Challenge: Surveys of Pupils and Teachers, 2005. Research Report RR718

    ERIC Educational Resources Information Center

    Ridley, Kate; Knight, Sarah; Scott, Emma; Benton, Tom; Woodthorpe, Adrian

    2006-01-01

    The London Challenge is a Department for Education and Skills (DfES) initiative, which aims to raise levels of attainment in London secondary schools and to create a world class education system in the capital. In 2005, London Challenge commissioned the National Foundation for Educational Research (NFER) to carry out a survey of Year 7 pupils,…

  16. Complexities in Subsetting Level 2 Data

    NASA Technical Reports Server (NTRS)

    Huwe, Paul; Wei, Jennifer; Meyer, David; Silberstein, David S.; Alfred, Jerome; Savtchenko, Andrey K.; Johnson, James E.; Albayrak, Arif; Hearty, Thomas

    2017-01-01

    Satellite Level 2 data presents unique challenges for tools and services. From nonlinear spatial geometry to inhomogeneous file data structure to inconsistent temporal variables to complex data variable dimensionality to multiple file formats, there are many difficulties in creating general tools for Level 2 data support. At NASA Goddard Earth Sciences Data and Information Services Center (GES DISC), we are implementing a general Level 2 Subsetting service for Level 2 data to a user-specified spatio-temporal region of interest (ROI). In this presentation, we will unravel some of the challenges faced in creating this service and the strategies we used to surmount them.

  17. Deep nursing: a thoughtful, co-created nursing process.

    PubMed

    Griffiths, Colin

    2017-03-30

    This article examines some of the challenges in nursing practice experienced by patients and nurses in the UK and Ireland, and considers some of the associated stressors in the system. Nurses must respond to these challenges by crafting their own practice, and the article offers a blueprint for developing personal nursing practice through acceptance, paying detailed attention to patients, taking time with patients and personal reflection. It draws on innovations in learning disability practice to suggest that care should be jointly thought through and co-created by patients and nurses, and that this process of thoughtful engagement constitutes 'deep nursing'.

  18. A platform for evolving intelligently interactive adversaries.

    PubMed

    Fogel, David B; Hays, Timothy J; Johnson, Douglas R

    2006-07-01

    Entertainment software developers face significant challenges in designing games with broad appeal. One of the challenges concerns creating nonplayer (computer-controlled) characters that can adapt their behavior in light of the current and prospective situation, possibly emulating human behaviors. This adaptation should be inherently novel, unrepeatable, yet within the bounds of realism. Evolutionary algorithms provide a suitable method for generating such behaviors. This paper provides background on the entertainment software industry, and details a prior and current effort to create a platform for evolving nonplayer characters with genetic and behavioral traits within a World War I combat flight simulator.

  19. Creating Standards-Based Technology Education Facilities

    ERIC Educational Resources Information Center

    Daugherty, Michael K.; Klenke, Andrew M.; Neden, Michael

    2008-01-01

    One of the most intimidating tasks faced by new or practicing technology education teachers is the challenge of creating new facilities or renovating current facilities for a new purpose. While the fourth program standard in "Advancing Excellence in Technological Literacy: Student Assessment, Professional Development, and Program Standards (AETL)"…

  20. Lessons learnt from 12 oral cholera vaccine campaigns in resource-poor settings.

    PubMed

    Hsiao, Amber; Desai, Sachin N; Mogasale, Vittal; Excler, Jean-Louis; Digilio, Laura

    2017-04-01

    Improving water and sanitation is the preferred choice for cholera control in the long-term. Nevertheless, vaccination is an available tool that has been shown to be a cost-effective option for cholera prevention in endemic countries or during outbreaks. In 2011 the first low-cost oral cholera vaccine for international use was given prequalification by the World Health Organization (WHO). To increase and prioritize use of the vaccine, WHO created a global stockpile in 2013 from which countries may request oral cholera vaccine for reactive campaigns. WHO has issued specific guidelines for applying for the vaccine, which was previously in short supply (despite prequalification for a second oral vaccine in 2015). The addition of a third WHO-prequalified oral cholera vaccine in 2016 is expected to increase the global stockpile considerably and alleviate supply issues. However, prioritization and best use of the vaccine (e.g. how, when and where to use) will remain challenges. We describe 12 past oral cholera vaccine campaigns, conducted in settings with varying burdens of cholera. These case studies illustrate three key challenges faced in the use of the oral cholera vaccines: regulatory hurdles, cold chain logistics and vaccine coverage and uptake. To pave the way for the introduction of current and future oral cholera vaccines, we discuss operational challenges and make recommendations for future research with respect to each of these challenges.

  1. Stakeholders' views on the ethical challenges of pragmatic trials investigating pharmaceutical drugs.

    PubMed

    Kalkman, Shona; van Thiel, Ghislaine J M W; Grobbee, Diederick E; Meinecke, Anna-Katharina; Zuidgeest, Mira G P; van Delden, Johannes J M

    2016-08-22

    We explored the views of key stakeholders to identify the ethical challenges of pragmatic trials investigating pharmaceutical drugs. A secondary aim was to capture stakeholders' attitudes towards the implementation of pragmatic trials in the drug development process. We conducted semistructured, in-depth interviews among individuals from different key stakeholder groups (academia and independent research institutions, the pharmaceutical industry, regulators, Health Technology Assessment (HTA) agencies and patients' organizations) through telephone or face-to-face sessions. Interviews were structured around the question "what challenges were experienced or perceived during the design, conduct and/or review of pragmatic trials." Respondents were additionally asked about their views on implementation of pragmatic trials in the drug development process. Thematic analysis was used to identify the ethically relevant features across data sets. We interviewed 34 stakeholders in 25 individual sessions and four group sessions. The four perceived challenges of ethical relevance were: (1) less controlled conditions creating safety concerns, (2) comparison with usual care potentially compromising clinical equipoise, (3) tailored or waivers of informed consent affecting patient autonomy, and (4) minimal interference with "real-world" practice reducing the knowledge value of trial results. We identified stakeholder concerns regarding risk assessment, use of suboptimal usual care as a comparator, tailoring of informed consent procedures and ensuring the social value of pragmatic trials. These concerns increased when respondents were asked about pragmatic trials conducted before market authorization.

  2. STEM Beyond The Classroom: Creating Authentic Outreach Programs That Build Bridges Between The Classroom And Real World Challenges

    NASA Astrophysics Data System (ADS)

    Ibarra, D. L.; Forder, S. E.; Pritchard, M.

    2014-12-01

    The ISF Academy was founded by Charles Kao, a Nobel Prize laureate. In 2011, the Shuyuan programs were established at The ISF Academy to operate both as a "school within a school" and as a "school outside the classroom." The Shuyuan programs work together with the IBO Science and Technology subject areas to develop comprehensive and challenging opportunities that address the 14 Grand Engineering Challenges. The goal is to establish co-curricular programs that go beyond the taught curriculum and support STEM curricula. Several programs outside of the classroom include an onsite robotics researcher, underwater and land based robotics programs, field trips, whole school food waste composting and the implementation of an energy tracking system. Relationships with several local universities allow students to work closely with professors in research settings and, annually, a leading researcher gives a keynote speech to our students. Other signature Shuyuan programs have developed international strategic relationships with the NRI at Cambridge University, where students spend several weeks studying science and civilization in China using primary source materials. Additionally, Shuyuan has supported extension opportunities for classroom teachers with institutional partnerships that include the British Council, governmental organizations, local universities, corporations, and NGOs. In conclusion, the overall goal of the Shuyuan Programs is to provide experiential learning opportunities that challenge conventional curriculum design in a manner that is supportive and innovative!

  3. Time for a change: addressing R&D and commercialization challenges for antibacterials

    PubMed Central

    Payne, David J.; Miller, Linda Federici; Findlay, David; Anderson, James; Marks, Lynn

    2015-01-01

    The antibacterial therapeutic area has been described as the perfect storm. Resistance is increasing to the point that our hospitals encounter patients infected with untreatable pathogens, the overall industry pipeline is described as dry and most multinational pharmaceutical companies have withdrawn from the area. Major contributing factors to the declining antibacterial industry pipeline include scientific challenges, clinical/regulatory hurdles and low return on investment. This paper examines these challenges and proposes approaches to address them. There is a need for a broader scientific agenda to explore new approaches to discover and develop antibacterial agents. Additionally, ideas of how industry and academia could be better integrated will be presented. While promising progress in the regulatory environment has been made, more streamlined regulatory paths are still required and the solutions will lie in global harmonization and clearly defined guidance. Creating the right incentives for antibacterial research and development is critical and a new commercial model for antibacterial agents will be proposed. One key solution to help resolve both the problem of antimicrobial resistance (AMR) and lack of new drug development are rapid, cost-effective, accurate point of care diagnostics that will transform antibacterial prescribing and enable more cost-effective and efficient antibacterial clinical trials. The challenges of AMR are too great for any one group to resolve and success will require leadership and partnerships among academia, industry and governments globally. PMID:25918443

  4. Lessons learnt from 12 oral cholera vaccine campaigns in resource-poor settings

    PubMed Central

    Desai, Sachin N; Mogasale, Vittal; Excler, Jean-Louis; Digilio, Laura

    2017-01-01

    Abstract Improving water and sanitation is the preferred choice for cholera control in the long-term. Nevertheless, vaccination is an available tool that has been shown to be a cost-effective option for cholera prevention in endemic countries or during outbreaks. In 2011 the first low-cost oral cholera vaccine for international use was given prequalification by the World Health Organization (WHO). To increase and prioritize use of the vaccine, WHO created a global stockpile in 2013 from which countries may request oral cholera vaccine for reactive campaigns. WHO has issued specific guidelines for applying for the vaccine, which was previously in short supply (despite prequalification for a second oral vaccine in 2015). The addition of a third WHO-prequalified oral cholera vaccine in 2016 is expected to increase the global stockpile considerably and alleviate supply issues. However, prioritization and best use of the vaccine (e.g. how, when and where to use) will remain challenges. We describe 12 past oral cholera vaccine campaigns, conducted in settings with varying burdens of cholera. These case studies illustrate three key challenges faced in the use of the oral cholera vaccines: regulatory hurdles, cold chain logistics and vaccine coverage and uptake. To pave the way for the introduction of current and future oral cholera vaccines, we discuss operational challenges and make recommendations for future research with respect to each of these challenges. PMID:28479625

  5. Inviting Student Engagement with Questioning

    ERIC Educational Resources Information Center

    Caram, Chris A.; Davis, Patsy B.

    2005-01-01

    Teaching is about designing, creating, and inventing intellectually challenging work for students--work that engages students and is so compelling that students persist when they experience difficulty and feel satisfaction, indeed delight, when they successfully accomplish the challenge (Schlechty 1997). Whether thinking skills are taught…

  6. Connected Building Challenge – Seattle Demonstration

    ScienceCinema

    Wang, Nora; Khamphanchai, Warodom; Chotibhongs, Tony; Hjortland, Andrew; David, Nigel; Bao, Han; Huang, Da-Wei; Shillingford, Kirk; Gutierrez, Lourdes; Kapadia, Priyank; Hagerman, Joe

    2018-06-13

    PNNL's first-ever innovation challenge invited teams to leverage PNNL's VOLTTRON technology to create solutions that advance the growth of the smart building market. Five teams presented their solutions at Seattle's Smart Buildings Center in early August 2016. This video summarizes the event.

  7. Using Medicare Data for Comparative Effectiveness Research – Opportunities and Challenges

    PubMed Central

    Fung, Vicki; Brand, Richard; Newhouse, Joseph; Hsu, John

    2013-01-01

    Background With the introduction of Part D drug benefits, Medicare collects information on diagnoses, treatments, and clinical events for millions of beneficiaries. These data are a promising resource for comparative effectiveness research (CER) on treatments, benefit designs, and delivery systems. Objectives We explore the data available for researchers and approaches that could be used to enhance the value of Medicare data for CER. Challenges and Opportunities Using currently available Medicare data for CER is challenging; as with all administrative data, it is not possible to capture every factor that contributes to prescribing decisions and patients are not randomly assigned to treatments. In addition, Part D plan selection and switching may influence treatment decisions and contribute to selection bias. Exploiting certain program aspects can help address these limitations. For example, ongoing changes in Medicare or plan policies, and the random assignment of beneficiaries who receive Part D low income subsidies into plans with different formularies could yield natural experiments. Policy implications Refining policies around time to data release, provision of additional data elements, and linkage with greater beneficiary-level information would improve the value and usability of these data. Improving the transparency and reproduceability of findings, and potential open access to qualified stakeholders are also important policy considerations. Work is needed to reconcile data needs with current policies and goals. Conclusions Medicare data provides a rich resource for CER. Leveraging existing program elements combined with some administrative changes in data availability could create large datasets for evaluating treatment patterns, spending, and coverage decisions. PMID:21819169

  8. Manufacturing and metrology for IR conformal windows and domes

    NASA Astrophysics Data System (ADS)

    Ferralli, Ian; Blalock, Todd; Brunelle, Matt; Lynch, Timothy; Myer, Brian; Medicus, Kate

    2017-05-01

    Freeform and conformal optics have the potential to dramatically improve optical systems by enabling systems with fewer optical components, reduced aberrations, and improved aerodynamic performance. These optical components differ from standard components in their surface shape, typically a non-symmetric equation based definition, and material properties. Traditional grinding and polishing tools are unable to handle these freeform shapes. Additionally, standard metrology tools cannot measure these surfaces. Desired substrates are typically hard ceramics, including poly-crystalline alumina or aluminum oxynitride. Notwithstanding the challenges that the hardness provides to manufacturing, these crystalline materials can be highly susceptible to grain decoration creating unacceptable scatter in optical systems. In this presentation, we will show progress towards addressing the unique challenges of manufacturing conformal windows and domes. Particular attention is given to our robotic polishing platform. This platform is based on an industrial robot adapted to accept a wide range of tooling and parts. The robot's flexibility has provided us an opportunity to address the unique challenges of conformal windows. Slurries and polishing active layers can easily be changed to adapt to varying materials and address grain decoration. We have the flexibility to change tool size and shape to address the varying sizes and shapes of conformal optics. In addition, the robotic platform can be a base for a deflectometry-based metrology tool to measure surface form error. This system, whose precision is independent of the robot's positioning accuracy, will allow us to measure optics in-situ saving time and reducing part risk. In conclusion, we will show examples of the conformal windows manufactured using our developed processes.

  9. EXTENSION EDUCATION SYMPOSIUM: Getting the most out of your extension appointment and still having a life.

    PubMed

    Powers, W; Cockett, N; Lardy, G

    2017-04-01

    Managing the demands of an academic appointment in extension can be a challenging task. Demands from constituent groups, expectations of supervisors, and rigors of promotion and tenure processes can create pressures that young faculty did not expect. Throw in spousal and family duties and you have created a situation that many will find hard to navigate. However, there are ways to cope and, even better news, there are ways to excel in meeting the demands of an academic appointment and enjoying life. Because many new extension faculty members do not have prior experience in extension, best practices in documenting programs and extension scholarship over the pretenure period are provided in this paper. Appointments that include both research and extension are quite common at many land grant universities. The advantages of joint appointments are numerous and include the fact that more and more grant agencies are seeking integrated research, teaching, and/or extension projects. However, the time demands of joint appointments can be challenging. Joint appointments can be designed to help faculty members conduct important translational research and have it be applied in a production setting. By seeking commonalities in research and extension efforts, joint appointments can be very synergistic. Development of highly successful programs requires planning on the front end with an emphasis on an in-depth needs assessment to determine stakeholder needs for both research and extension. Impact assessment should be part of this planning effort. Performing as a successful extension faculty member while maintaining relationships outside of work is challenging and requires deliberate effort on the part of employees and supervisors to realize there is more to life than work. Some authors have referred to this as work-life balance, but it may be more helpful to think of it as work-life effectiveness. To do this, one needs to 1) define what success looks like, 2) set boundaries and maintain control including control of your schedule, and 3) find time to ensure your physical, emotional, and spiritual well-being are nurtured in addition to your professional development. In summary, extension careers can be challenging at times as demands and expectations of stakeholders, supervisors, and rigors of the tenure system create formidable obstacles. However, by keeping a focus on the priorities of the position and looking for synergy in research and extension work, they can actually be quite enjoyable and very rewarding.

  10. Celebrating Difference: Best Practices in Culturally Responsive Teaching Online

    ERIC Educational Resources Information Center

    Woodley, Xeturah; Hernandez, Cecilia; Parra, Julia; Negash, Beyan

    2017-01-01

    Culturally responsive teaching and design practices flip the online classroom by creating an environment that acknowledges, celebrates, and builds upon the cultural capital that learners and teachers bring to the online classroom. Challenges exist in all phases of online course design, including the ability to create online courses that reflect…

  11. Learning from Student Data

    ERIC Educational Resources Information Center

    Pruitt, Kobie

    2016-01-01

    Just as adults' personal lives and data are increasingly inhabiting online spaces, so are students. While this shift brings many benefits and the possibility of learning tailored to individual students' needs, it is also brings new challenges. Students create an electronic trail of information that creates an obvious concern: How can they enjoy…

  12. INNOVATIVE BIODIESEL PRODUCTION: A SOLUTION TO THE SCIENTIFIC, TECHNICAL, AND EDUCATIONAL CHALLENGES OF SUSTAINABILITY

    EPA Science Inventory

    Loyola's STEP students completed over 20 team projects: Developed a business plan for biodiesel production, created the LUC biodiesel website, created the Bio­shorts documentaries, tabled at environmental events, publicized and put on two Biodiesel Forums (2nd one pending,...

  13. Understanding Effective Program Improvement Schools through a Distributed Leadership Task Context Model

    ERIC Educational Resources Information Center

    Gipson, Frances Marie

    2012-01-01

    Federal, state, and local agencies face challenges organizing resources that create the conditions necessary to create, sustain, and replicate effective high performing schools. Knowing that leadership does impact achievement outcomes and that school districts tackle growing numbers of sanctioned Program Improvement schools, a distributed…

  14. Beyond knowledge capture: creating useful work-centric systems

    NASA Technical Reports Server (NTRS)

    Cooper, L. P.; Majchrzak, A.

    2001-01-01

    Once you have successfully captured knowledge, the challenge then becomes one of creating an affective way to use that knowledge. Two high knowledge content systems developed at the Jet Propulsion Laboratory are presented as examples of work-centric systems, where the primary value to the user is in the content.

  15. Shared Geospatial Metadata Repository for Ontario University Libraries: Collaborative Approaches

    ERIC Educational Resources Information Center

    Forward, Erin; Leahey, Amber; Trimble, Leanne

    2015-01-01

    Successfully providing access to special collections of digital geospatial data in academic libraries relies upon complete and accurate metadata. Creating and maintaining metadata using specialized standards is a formidable challenge for libraries. The Ontario Council of University Libraries' Scholars GeoPortal project, which created a shared…

  16. MASS SPECTROMETRY OF DRINKING WATER CONTAMINANTS: DISINFECTION BY-PRODUCTS AND THE US EPA CONTAMINANT CANDIDATE LIST COMPOUNDS

    EPA Science Inventory

    Disinfection by-products (DBPs) are the thousands of compounds created during the disinfection of drinking water. These compounds can create potential health risks, challenge drinking water treatment technology, and pose difficulties in their analysis. Research in the use of ga...

  17. Globalisation, Mergers and "Inadvertent Multi-Campus Universities": Reflections from Wales

    ERIC Educational Resources Information Center

    Zeeman, Nadine; Benneworth, Paul

    2017-01-01

    Multi-site universities face the challenge of integrating campuses that may have different profiles and orientations arising from place-specific attachments. Multi-campus universities created via mergers seeking to ensure long-term financial sustainability, and increasing their attractiveness to students, create a tension in campuses' purposes. We…

  18. Improving the Design of Workplace E-Learning Research

    ERIC Educational Resources Information Center

    Dubois, Cathy; Long, Lori

    2012-01-01

    E-learning researchers face considerable challenges in creating meaningful and generalizable studies due to the complex nature of this dynamic training medium. Our experience in conducting workplace e-learning research led us to create this guide for planning research on e-learning. We share the unanticipated complications we encountered in our…

  19. Creating Sustainable Societies: Developing Emerging Professionals through Transforming Current Mindsets

    ERIC Educational Resources Information Center

    Griswold, Wendy

    2017-01-01

    Future professionals will bear the brunt of creating sustainable societies. Equipping them for the task is the challenge of current educators. Educational experiences facilitating the development of sustainable habits of mind are needed. This research reports on the experiences of developing scientists and engineers engaged in a sustainable energy…

  20. Creating Opportunities for Undocumented Youth: A Review of the Literature

    ERIC Educational Resources Information Center

    Varela, Alejandra M.

    2011-01-01

    The increasing number of undocumented immigrants coming to the United States has created serious socioeconomic, sociocultural, and socioeducational challenges for the communities in which these immigrants settle. Minors represent over 1.3 million of the 10.8 million unauthorized immigrants presently living in the United States. Given the secretive…

  1. Culturally Responsive Teaching Knowledge and Practices of Online Faculty

    ERIC Educational Resources Information Center

    Heitner, Keri L.; Jennings, Miranda

    2016-01-01

    Cultural differences between faculty and their students can create important challenges that affect the quality and efficacy of online teaching and learning. The objectives of this study were to: (a) create and pilot test an assessment for online faculty to measure culturally responsive teaching knowledge (CRT) and culturally responsive…

  2. The Challenges of Creating a Benchmarking Process for Administrative and Support Services

    ERIC Educational Resources Information Center

    Manning, Terri M.

    2007-01-01

    In the current climate of emphasis on outcomes assessment, colleges and universities are working diligently to create assessment processes for student learning outcomes, competence in general education, student satisfaction with services, and electronic tracking media to document evidence of competence in graduates. Benchmarking has become a…

  3. Viewpoint: The Challenge of Creating Engaged Public Research Universities

    ERIC Educational Resources Information Center

    Cherwitz, Rick

    2010-01-01

    The quest to create engaged public research universities requires academe to confront a stark reality: inflexible administrative structures, historically embedded practices, status-quo thinking, and inertia. Until these obstacles are overcome, the retreat from public life will not be arrested. In this article, the author provides a sample of the…

  4. Synchronous Learning Best Practices: An Action Research Study

    ERIC Educational Resources Information Center

    Warden, Clyde A.; Stanworth, James O.; Ren, Jian Biao; Warden, Antony R.

    2013-01-01

    Low cost and significant advances in technology now allow instructors to create their own virtual learning environments. Creating social interactions within a virtual space that emulates the physical classroom remains challenging. While students are familiar with virtual worlds and video meetings, they are inexperienced as virtual learners. Over a…

  5. A Provably Necessary Symbiosis

    ERIC Educational Resources Information Center

    Hochberg, Robert; Gabric, Kathleen

    2010-01-01

    The "new biology" of the 21st century is increasingly dependent on mathematics, and preparing high school students to have both strong science and math skills has created major challenges for both disciplines. Researchers and educators in biology and mathematics have been working long hours on a project to create high school teaching modules…

  6. Great Performances: Creating Classroom-Based Assessment Tasks. Second Edition

    ERIC Educational Resources Information Center

    Shoemaker, Betty; Lewin, Larry

    2011-01-01

    Get an in-depth understanding of how to create fun, engaging, and challenging performance assessments that require students to elaborate on content and demonstrate mastery of skills. This update of an ASCD (Association for Supervision and Curriculum Development) classic includes new scoring methods, reading assessments, and insights on navigating…

  7. Creation and genomic analysis of irradiation hybrids in Populus

    Treesearch

    Matthew S. Zinkgraf; K. Haiby; M.C. Lieberman; L. Comai; I.M. Henry; Andrew Groover

    2016-01-01

    Establishing efficient functional genomic systems for creating and characterizing genetic variation in forest trees is challenging. Here we describe protocols for creating novel gene-dosage variation in Populus through gamma-irradiation of pollen, followed by genomic analysis to identify chromosomal regions that have been deleted or inserted in...

  8. Towards Critical Appraisal of Infographics as Scientific Inscriptions

    ERIC Educational Resources Information Center

    Polman, Joseph L.; Gebre, Engida H.

    2015-01-01

    Teaching young adults about interpreting and creating the sort of multimodal infographics increasingly prevalent in science communication creates considerable challenges for teachers and practitioners, as there is no guide to determine the quality or effectiveness of this new genre of inscriptional forms, and to scaffold students' performances in…

  9. Automatic pattern localization across layout database and photolithography mask

    NASA Astrophysics Data System (ADS)

    Morey, Philippe; Brault, Frederic; Beisser, Eric; Ache, Oliver; Röth, Klaus-Dieter

    2016-03-01

    Advanced process photolithography masks require more and more controls for registration versus design and critical dimension uniformity (CDU). The distribution of the measurement points should be distributed all over the whole mask and may be denser in areas critical to wafer overlay requirements. This means that some, if not many, of theses controls should be made inside the customer die and may use non-dedicated patterns. It is then mandatory to access the original layout database to select patterns for the metrology process. Finding hundreds of relevant patterns in a database containing billions of polygons may be possible, but in addition, it is mandatory to create the complete metrology job fast and reliable. Combining, on one hand, a software expertise in mask databases processing and, on the other hand, advanced skills in control and registration equipment, we have developed a Mask Dataprep Station able to select an appropriate number of measurement targets and their positions in a huge database and automatically create measurement jobs on the corresponding area on the mask for the registration metrology system. In addition, the required design clips are generated from the database in order to perform the rendering procedure on the metrology system. This new methodology has been validated on real production line for the most advanced process. This paper presents the main challenges that we have faced, as well as some results on the global performances.

  10. To kill a kangaroo: understanding the decision to pursue high-risk/high-gain resources.

    PubMed

    Jones, James Holland; Bird, Rebecca Bliege; Bird, Douglas W

    2013-09-22

    In this paper, we attempt to understand hunter-gatherer foraging decisions about prey that vary in both the mean and variance of energy return using an expected utility framework. We show that for skewed distributions of energetic returns, the standard linear variance discounting (LVD) model for risk-sensitive foraging can produce quite misleading results. In addition to creating difficulties for the LVD model, the skewed distributions characteristic of hunting returns create challenges for estimating probability distribution functions required for expected utility. We present a solution using a two-component finite mixture model for foraging returns. We then use detailed foraging returns data based on focal follows of individual hunters in Western Australia hunting for high-risk/high-gain (hill kangaroo) and relatively low-risk/low-gain (sand monitor) prey. Using probability densities for the two resources estimated from the mixture models, combined with theoretically sensible utility curves characterized by diminishing marginal utility for the highest returns, we find that the expected utility of the sand monitors greatly exceeds that of kangaroos despite the fact that the mean energy return for kangaroos is nearly twice as large as that for sand monitors. We conclude that the decision to hunt hill kangaroos does not arise simply as part of an energetic utility-maximization strategy and that additional social, political or symbolic benefits must accrue to hunters of this highly variable prey.

  11. Social Skills Assessment and Intervention for Children and Youth

    ERIC Educational Resources Information Center

    Gresham, Frank M.

    2016-01-01

    Children and youth with deficits in social competence present substantial challenges for schools, teachers, parents and peers. These challenges cut across disciplinary, instructional and interpersonal domains and they frequently create chaotic home, school and classroom environments. Schools are charged with teaching an increasingly diverse…

  12. The Challenge of Urban Policy

    ERIC Educational Resources Information Center

    Glaeser, Edward L.

    2012-01-01

    Urbanization almost invariably accompanies development, and the cities of India and China are experiencing spectacular increases in population. The concentration of millions of people in a small mass creates challenges for public policy, especially in the areas of basic infrastructure, public health, traffic congestion, and often law enforcement…

  13. CHALLENGES AND BENEFITS OF CONDUCTING ENVIRONMENTAL JUSTICE RESEARCH IN A SCHOOL SETTING

    PubMed Central

    GUIDRY, VIRGINIA T.; LOWMAN, AMY; HALL, DEVON; BARON, DOTHULA; WING, STEVE

    2015-01-01

    Environmental justice (EJ) research requires attention to consequences for research participants beyond those typically considered by institutional review boards. The imbalance of power between impacted communities and those who create and regulate pollution creates challenges for participation, yet research can also benefit those involved. Our community-academic partnership designed the Rural Air Pollutants and Children's Health (RAPCH) study to provide positive impacts while measuring health effects at three low-resource public middle schools near concentrated animal feeding operations (CAFOs) in North Carolina. We evaluated perceived benefits and challenges of study involvement by interviewing school staff and community liaisons who facilitated data collection. Reported benefits included enhancement of students’ academic environment and increased community environmental awareness; challenges were associated mainly with some participants’ immaturity. Leadership from a strong community-based organization was crucial to recruitment, yet our approach entailed minimal focus on EJ, which may have limited opportunities for community education or organizing for environmental health. PMID:25085828

  14. Dihydroquinazolines as a novel class of Trypanosoma brucei trypanothione reductase inhibitors: discovery, synthesis, and characterization of their binding mode by protein crystallography.

    PubMed

    Patterson, Stephen; Alphey, Magnus S; Jones, Deuan C; Shanks, Emma J; Street, Ian P; Frearson, Julie A; Wyatt, Paul G; Gilbert, Ian H; Fairlamb, Alan H

    2011-10-13

    Trypanothione reductase (TryR) is a genetically validated drug target in the parasite Trypanosoma brucei , the causative agent of human African trypanosomiasis. Here we report the discovery, synthesis, and development of a novel series of TryR inhibitors based on a 3,4-dihydroquinazoline scaffold. In addition, a high resolution crystal structure of TryR, alone and in complex with substrates and inhibitors from this series, is presented. This represents the first report of a high resolution complex between a noncovalent ligand and this enzyme. Structural studies revealed that upon ligand binding the enzyme undergoes a conformational change to create a new subpocket which is occupied by an aryl group on the ligand. Therefore, the inhibitor, in effect, creates its own small binding pocket within the otherwise large, solvent exposed active site. The TryR-ligand structure was subsequently used to guide the synthesis of inhibitors, including analogues that challenged the induced subpocket. This resulted in the development of inhibitors with improved potency against both TryR and T. brucei parasites in a whole cell assay.

  15. Development of a Mapped Diabetes Community Program Guide for a Safety Net Population

    PubMed Central

    Zallman, Leah; Ibekwe, Lynn; Thompson, Jennifer W.; Ross-Degnan, Dennis; Oken, Emily

    2014-01-01

    Purpose Enhancing linkages between patients and community programs is increasingly recognized as a method for improving physical activity, nutrition and weight management. Although interactive mapped community program guides may be beneficial, there remains a dearth of articles that describe the processes and practicalities of creating such guides. This article describes the development of an interactive, web-based mapped community program guide at a safety net institution and the lessons learned from that process. Conclusions This project demonstrated the feasibility of creating two maps – a program guide and a population health map. It also revealed some key challenges and lessons for future work in this area, particularly within safety-net institutions. Our work underscores the need for developing partnerships outside of the health care system and the importance of employing community-based participatory methods. In addition to facilitating improvements in individual wellness, mapping community programs also has the potential to improve population health management by healthcare delivery systems such as hospitals, health centers, or public health systems, including city and state departments of health. PMID:24752180

  16. Strategy of Planetary Data Archives in Japanese Missions for Planetary Data System

    NASA Astrophysics Data System (ADS)

    Yamamoto, Y.; Ishihara, Y.; Murakami, S. Y.

    2017-12-01

    To preserve data acquired by Japanese planetary explorations for a long time, we need a data archiving strategy in a form suitable for resources. Planetary Data System(PDS) developed by NASA is an excellent system for saving data over a long period. Especially for the current version 4 (PDS4), it is possible to create a data archive with high completeness using information technology. Historically, the Japanese planetary missions have archived data by scientists in their ways, but in the past decade, JAXA has been aiming to conform data to PDS considering long term preservation. Hayabusa, Akatsuki are archived in PDS3. Kaguya(SELENE) data have been newly converted from the original format to PDS3. Hayabusa2 and BepiColombo, and future planetary explorations will release data in PDS4. The cooperation of engineers who are familiar with information technology is indispensable to create data archives for scientists. In addition, it is essential to have experience, information sharing, and a system to support it. There is a challenge in Japan about the system.

  17. Engineering long term clinical success of advanced ceramic prostheses.

    PubMed

    Rekow, Dianne; Thompson, Van P

    2007-01-01

    Biocompatability and, in some applications, esthetics make all-ceramic prostheses compelling choices but despite significant improvements in materials properties and toughening mechanisms, these still have significant failure rates. Factors that contribute to the degradation in strength and survival include material selection and prosthesis design which set the upper limit for performance. However, fabrication operations introduce damage that can be exacerbated by environmental conditions and clinical function. Using all-ceramic dental crowns as an example, experimentally derived models provide insight into the relationships between materials properties and initial critical loads to failure. Analysis of fabrication operations suggests strategies to minimize damage. Environmental conditions can create viscoplastic flow of supporting components which can contribute additional stress within the prosthesis. Fatigue is a particularly challenging problem, not only providing the energy to propagate existing damage but, when combined with the wet environment, can create new damage modes. While much is known, the influence of these new damage modes has not been completely elucidated. The role of complex prosthesis geometry and its interaction with other factors on damage initiation and propagation has yet to be well characterized.

  18. Catalyst design with atomic layer deposition

    DOE PAGES

    O'Neill, Brandon J.; Jackson, David H. K.; Lee, Jechan; ...

    2015-02-06

    Atomic layer deposition (ALD) has emerged as an interesting tool for the atomically precise design and synthesis of catalytic materials. Herein, we discuss examples in which the atomic precision has been used to elucidate reaction mechanisms and catalyst structure-property relationships by creating materials with a controlled distribution of size, composition, and active site. We highlight ways ALD has been utilized to design catalysts with improved activity, selectivity, and stability under a variety of conditions (e.g., high temperature, gas and liquid phase, and corrosive environments). In addition, due to the flexibility and control of structure and composition, ALD can create myriadmore » catalytic structures (e.g., high surface area oxides, metal nanoparticles, bimetallic nanoparticles, bifunctional catalysts, controlled microenvironments, etc.) that consequently possess applicability for a wide range of chemical reactions (e.g., CO 2 conversion, electrocatalysis, photocatalytic and thermal water splitting, methane conversion, ethane and propane dehydrogenation, and biomass conversion). Lastly, the outlook for ALD-derived catalytic materials is discussed, with emphasis on the pending challenges as well as areas of significant potential for building scientific insight and achieving practical impacts.« less

  19. Advancing three-dimensional MEMS by complimentary laser micro manufacturing

    NASA Astrophysics Data System (ADS)

    Palmer, Jeremy A.; Williams, John D.; Lemp, Tom; Lehecka, Tom M.; Medina, Francisco; Wicker, Ryan B.

    2006-01-01

    This paper describes improvements that enable engineers to create three-dimensional MEMS in a variety of materials. It also provides a means for selectively adding three-dimensional, high aspect ratio features to pre-existing PMMA micro molds for subsequent LIGA processing. This complimentary method involves in situ construction of three-dimensional micro molds in a stand-alone configuration or directly adjacent to features formed by x-ray lithography. Three-dimensional micro molds are created by micro stereolithography (MSL), an additive rapid prototyping technology. Alternatively, three-dimensional features may be added by direct femtosecond laser micro machining. Parameters for optimal femtosecond laser micro machining of PMMA at 800 nanometers are presented. The technical discussion also includes strategies for enhancements in the context of material selection and post-process surface finish. This approach may lead to practical, cost-effective 3-D MEMS with the surface finish and throughput advantages of x-ray lithography. Accurate three-dimensional metal microstructures are demonstrated. Challenges remain in process planning for micro stereolithography and development of buried features following femtosecond laser micro machining.

  20. Catalyst design with atomic layer deposition

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    O'Neill, Brandon J.; Jackson, David H. K.; Lee, Jechan

    Atomic layer deposition (ALD) has emerged as an interesting tool for the atomically precise design and synthesis of catalytic materials. Herein, we discuss examples in which the atomic precision has been used to elucidate reaction mechanisms and catalyst structure-property relationships by creating materials with a controlled distribution of size, composition, and active site. We highlight ways ALD has been utilized to design catalysts with improved activity, selectivity, and stability under a variety of conditions (e.g., high temperature, gas and liquid phase, and corrosive environments). In addition, due to the flexibility and control of structure and composition, ALD can create myriadmore » catalytic structures (e.g., high surface area oxides, metal nanoparticles, bimetallic nanoparticles, bifunctional catalysts, controlled microenvironments, etc.) that consequently possess applicability for a wide range of chemical reactions (e.g., CO 2 conversion, electrocatalysis, photocatalytic and thermal water splitting, methane conversion, ethane and propane dehydrogenation, and biomass conversion). Lastly, the outlook for ALD-derived catalytic materials is discussed, with emphasis on the pending challenges as well as areas of significant potential for building scientific insight and achieving practical impacts.« less

  1. Infrastructural considerations for supporting POC devices. Healthcare executives must focus on creating integration-friendly environments for the most effective use of mobile devices.

    PubMed

    Hashem, Ahmad; Ruggeri, Roberto

    2003-01-01

    Creating an integration-friendly infrastructure is the best way to prepare for current as well as next-generation POC devices. Fortunately, hassle-free system integration is needed throughout healthcare today for reasons beyond the domain of POC devices, so integration progress already made in other areas helps pave the way for POC devices. Healthcare IT professionals, as much or more than any other IT group, have had to deal with the challenges of integrating disparate systems. When considering deployment of POC devices, you will want to make sure they adhere to open industry standards. In this way, these important devices won't add to the problem of disparate systems, but will contribute to the solution. We see XML and Web services as being especially important to the future of healthcare delivery and administration. XML and Web services, along with powerful orchestrators, can provide an ever-richer collection of clinical data to be delivered to, and received from, the POC devices that will become an ever more important addition to the physician armamentarium.

  2. Interferences from blood collection tube components on clinical chemistry assays

    PubMed Central

    Bowen, Raffick A.R.; Remaley, Alan T.

    2014-01-01

    Improper design or use of blood collection devices can adversely affect the accuracy of laboratory test results. Vascular access devices, such as catheters and needles, exert shear forces during blood flow, which creates a predisposition to cell lysis. Components from blood collection tubes, such as stoppers, lubricants, surfactants, and separator gels, can leach into specimens and/or adsorb analytes from a specimen; special tube additives may also alter analyte stability. Because of these interactions with blood specimens, blood collection devices are a potential source of pre-analytical error in laboratory testing. Accurate laboratory testing requires an understanding of the complex interactions between collection devices and blood specimens. Manufacturers, vendors, and clinical laboratorians must consider the pre-analytical challenges in laboratory testing. Although other authors have described the effects of endogenous substances on clinical assay results, the effects/impact of blood collection tube additives and components have not been well systematically described or explained. This review aims to identify and describe blood collection tube additives and their components and the strategies used to minimize their effects on clinical chemistry assays. PMID:24627713

  3. 2011 Green Flight Challenge Highlights Video for Awards Ceremony

    NASA Image and Video Library

    2011-10-03

    On Monday, October 3, 2011, NASA's Centennial Challenges program awarded the largest prize in aviation history, created to inspire the development of more fuel-efficient aircraft and spark the start of a new electric airplane industry. Three teams successfully met all requirements and competed for the $1.65 million purse in the CAFE Green Flight Challenge, sponsored by Google, over the skies of Santa Rosa, California.

  4. 77 FR 17060 - Announcement of Requirements and Registration for Beat Down Blood Pressure Challenge

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-23

    ....Challenge.gov and must provide: The title of the Video; A link to the Video on YouTube.com or Vimeo.com (the.... This step ensures that you will receive important challenge updates. 3. Create a video and ensure the... longer than 2 minutes. 4. Confirm that you have read and agreed to the Official Rules. A Contestant will...

  5. Student Reflections on Learning with Challenging Tasks: "I Think the Worksheets Were Just for Practice, and the Challenges Were for Maths"

    ERIC Educational Resources Information Center

    Russo, James; Hopkins, Sarah

    2017-01-01

    The current study considered young students' (7 and 8 years old) experiences and perceptions of mathematics lessons involving challenging (i.e. cognitively demanding) tasks. We used the Constant Comparative Method to analyse the interview responses (n = 73) regarding what work artefacts students were most proud of creating and why. Five themes…

  6. Predictive Systems for Customer Interactions

    NASA Astrophysics Data System (ADS)

    Vijayaraghavan, Ravi; Albert, Sam; Singh, Vinod Kumar; Kannan, Pallipuram V.

    With the coming of age of web as a mainstream customer service channel, B2C companies have invested substantial resources in enhancing their web presence. Today customers can interact with a company, not only through the traditional phone channel but also through chat, email, SMS or web self-service. Each of these channels is best suited for some services and ill-matched for others. Customer service organizations today struggle with the challenge of delivering seamlessly integrated services through these different channels. This paper will evaluate some of the key challenges in multi-channel customer service. It will address the challenge of creating the right channel mix i.e. providing the right choice of channels for a given customer/behavior/issue profile. It will also provide strategies for optimizing the performance of a given channel in creating the right customer experience.

  7. Cognitive Bias in the Verification and Validation of Space Flight Systems

    NASA Technical Reports Server (NTRS)

    Larson, Steve

    2012-01-01

    Cognitive bias is generally recognized as playing a significant role in virtually all domains of human decision making. Insight into this role is informally built into many of the system engineering practices employed in the aerospace industry. The review process, for example, typically has features that help to counteract the effect of bias. This paper presents a discussion of how commonly recognized biases may affect the verification and validation process. Verifying and validating a system is arguably more challenging than development, both technically and cognitively. Whereas there may be a relatively limited number of options available for the design of a particular aspect of a system, there is a virtually unlimited number of potential verification scenarios that may be explored. The probability of any particular scenario occurring in operations is typically very difficult to estimate, which increases reliance on judgment that may be affected by bias. Implementing a verification activity often presents technical challenges that, if they can be overcome at all, often result in a departure from actual flight conditions (e.g., 1-g testing, simulation, time compression, artificial fault injection) that may raise additional questions about the meaningfulness of the results, and create opportunities for the introduction of additional biases. In addition to mitigating the biases it can introduce directly, the verification and validation process must also overcome the cumulative effect of biases introduced during all previous stages of development. A variety of cognitive biases will be described, with research results for illustration. A handful of case studies will be presented that show how cognitive bias may have affected the verification and validation process on recent JPL flight projects, identify areas of strength and weakness, and identify potential changes or additions to commonly used techniques that could provide a more robust verification and validation of future systems.

  8. Probabilistic Impact Assessment of Domestic Rainwater Harvesting in Urban Slums: West Africa Case Study

    NASA Astrophysics Data System (ADS)

    Cowden, J. R.; Watkins, D. W.; Mihelcic, J. R.; Fry, L. M.

    2007-12-01

    Urban populations now exceed rural populations worldwide, creating unique challenges in providing basic services, especially in developing countries where informal or illegal settlements grow in peri-urban areas. West Africa is an acute example of the problems created by rapid urban growth, with high levels of urban poverty and low water and sanitation access rates. Although considerable effort has been made in providing improved water access and urban services to slum communities, research indicates that clean water access rates are not keeping up with urbanization rates in several areas of the world and that rapidly growing slum communities are beginning to overwhelm many prior water improvements projects. In the face of these challenges, domestic rainwater harvesting is proposed as a technologically appropriate and economically viable option for enhancing water supplies to urban slum households. However, assessing the reliability, potential health impacts, and overall cost-effectiveness of these systems on a regional level is difficult for several reasons. First, long daily rainfall records are not readily available in much of the developing world, including many regions of sub-Saharan Africa. Second, significant uncertainties exist in the relevant cost, water use, and health data. Third, to estimate the potential future impacts at the regional scale, various global change scenarios should be investigated. Finally, in addition to these technical challenges, there is also a need to develop relatively simple and transparent assessment methods for informing policy makers. A procedure is presented for assessment of domestic rainwater harvesting systems using a combination of scenario, sensitivity, and trade-off analyses. Using data from West Africa, simple stochastic weather models are developed to generate rainfall sequences for the region, which are then used to estimate the reliability of providing a range of per capita water supplies. Next, a procedure is proposed for quantifying the health impacts of improved water supplies, and sensitivity analysis of cost and health data provides an indication of cost- effectiveness. Climate change impacts are assessed via weather model parameter adjustment according to statistical downscaling of general circulation model output. Future work involving the interpolation of model parameters to ungaged sites, incorporation of additional global change scenarios (e.g., population, emissions), and extension of the procedure to a full Monte Carlo analysis will be discussed as time allows.

  9. Preschool Gifted Education: Perceived Challenges Associated with Program Development

    ERIC Educational Resources Information Center

    Kettler, Todd; Oveross, Mattie E.; Salman, Rania C.

    2017-01-01

    This descriptive study investigated the challenges related to implementing gifted education services in preschool centers. Participants were 254 licensed preschool center directors in a southern state. Participants completed a researcher-created survey including both selected response items and constructed response items to examine the perceived…

  10. Managing Information in Law Firms: Changes and Challenges

    ERIC Educational Resources Information Center

    Evans, Nina; Price, James

    2017-01-01

    Introduction. Data, information and knowledge together constitute a vital business asset for every organization that enables every business activity, every business process and every business decision. The global legal industry is facing unprecedented change, which inevitably creates challenges for individual law firms. These global changes affect…

  11. Teaching Sustainable Design Using BIM and Project-Based Energy Simulations

    ERIC Educational Resources Information Center

    Shen, Zhigang; Jensen, Wayne; Wentz, Timothy; Fischer, Bruce

    2012-01-01

    The cross-disciplinary nature of energy-efficient building design has created many challenges for architecture, engineering and construction instructors. One of the technical challenges in teaching sustainable building design is enabling students to quantitatively understand how different building designs affect a building's energy performance.…

  12. Creating Asset-Rich Communities

    ERIC Educational Resources Information Center

    Miller, Teresa Northern; Leslie-Toogood, Adrienne; Kaff, Marilyn

    2005-01-01

    Adolescents today face increasing challenges, while the support systems that should help them meet and surmount those challenges are rapidly disappearing. Yearly statistics on teen substance abuse, depression, suicide, and violent crime continue to escalate. Teens with low attachments to school are most vulnerable because they are less likely to…

  13. The Future of Educational Entrepreneurship: Possibilities for School Reform

    ERIC Educational Resources Information Center

    Hess, Frederick M., Ed.

    2008-01-01

    "The Future of Educational Entrepreneurship" examines the challenge of creating innovative and productive entrepreneurial activity in American education. In the course of exploring these challenges, the book considers a number of crucial issues and circumstances: existing "barriers to entry" that prohibit or obstruct entrepreneurial efforts; the…

  14. How to Survive the First Year of Teaching.

    ERIC Educational Resources Information Center

    Harris, Judy J.

    2003-01-01

    Discusses the unique challenges of the first year of teaching. Challenges include over enrollment, long hours, and overload of paperwork. Gives advice on how new teachers can overcome problems by creating alliances within the spiritual community, working with administrators, and taking care of their health. (MZ)

  15. People with Learning Disabilities and "Active Ageing"

    ERIC Educational Resources Information Center

    Foster, Liam; Boxall, Kathy

    2015-01-01

    Background: People (with and without learning disabilities) are living longer. Demographic ageing creates challenges and the leading policy response to these challenges is "active ageing". "Active" does not just refer to the ability to be physically and economically active, but also includes ongoing social and civic engagement…

  16. Internationalizing Business Education for Globally Competent Managers

    ERIC Educational Resources Information Center

    Kedia, Ben L.; Englis, Paula D.

    2011-01-01

    The world is shrinking as developments in technology and transportation rapidly increase global opportunities and challenges for businesses. Furthermore, developing markets are becoming increasingly important, creating new challenges for managers. Business education must step in and prepare graduates to work in and with these markets. This article…

  17. User-Centered Design of a Tablet Waiting Room Tool for Complex Patients to Prioritize Discussion Topics for Primary Care Visits.

    PubMed

    Lyles, Courtney R; Altschuler, Andrea; Chawla, Neetu; Kowalski, Christine; McQuillan, Deanna; Bayliss, Elizabeth; Heisler, Michele; Grant, Richard W

    2016-09-14

    Complex patients with multiple chronic conditions often face significant challenges communicating and coordinating with their primary care physicians. These challenges are exacerbated by the limited time allotted to primary care visits. Our aim was to employ a user-centered design process to create a tablet tool for use by patients for visit discussion prioritization. We employed user-centered design methods to create a tablet-based waiting room tool that enables complex patients to identify and set discussion topic priorities for their primary care visit. In an iterative design process, we completed one-on-one interviews with 40 patients and their 17 primary care providers, followed by three design sessions with a 12-patient group. We audiorecorded and transcribed all discussions and categorized major themes. In addition, we met with 15 key health communication, education, and technology leaders within our health system to further review the design and plan for broader implementation of the tool. In this paper, we present the significant changes made to the tablet tool at each phase of this design work. Patient feedback emphasized the need to make the tablet tool accessible for patients who lacked technical proficiency and to reduce the quantity and complexity of text presentation. Both patients and their providers identified specific content choices based on their personal experiences (eg, the ability to raise private or sensitive concerns) and recommended targeting new patients. Stakeholder groups provided essential input on the need to augment text with video and to create different versions of the videos to match sex and race/ethnicity of the actors with patients. User-centered design in collaboration with patients, providers, and key health stakeholders led to marked evolution in the initial content, layout, and target audience for a tablet waiting room tool intended to assist complex patients with setting visit discussion priorities.

  18. Understanding Global Change (UGC) as a Unifying Conceptual Framework for Teaching Ecology: Using UGC in a High School Biology Program to Integrate Earth Science and Biology, and to Demonstrate the Value of Modeling Global Systems in Promoting Conceptual Learning

    NASA Astrophysics Data System (ADS)

    Levine, J.; Bean, J. R.

    2017-12-01

    Global change science is ideal for NGSS-informed teaching, but presents a serious challenge to K-12 educators because it is complex and interdisciplinary- combining earth science, biology, chemistry, and physics. Global systems are themselves complex. Adding anthropogenic influences on those systems creates a formidable list of topics - greenhouse effect, climate change, nitrogen enrichment, introduced species, land-use change among them - which are often presented as a disconnected "laundry list" of "facts." This complexity, combined with public and mass-media scientific illiteracy, leaves global change science vulnerable to misrepresentation and politicization, creating additional challenges to teachers in public schools. Ample stand-alone, one-off, online resources, many of them excellent, are (to date) underutilized by teachers in the high school science course taken by most students: biology. The Understanding Global Change project (UGC) from the UC Berkeley Museum of Paleontology has created a conceptual framework that organizes, connects, and explains global systems, human and non-human drivers of change in those systems, and measurable changes in those systems. This organization and framework employ core ideas, crosscutting concepts, structure/function relationships, and system models in a unique format that facilitates authentic understanding, rather than memorization. This system serves as an organizing framework for the entire ecology unit of a forthcoming mainstream high school biology program. The UGC system model is introduced up front with its core informational graphic. The model is elaborated, step by step, by adding concepts and processes as they are introduced and explained in each chapter. The informational graphic is thus used in several ways: to organize material as it is presented, to summarize topics in each chapter and put them in perspective, and for review and critical thinking exercises that supplement the usual end-of-chapter lists of key terms.

  19. Steps Toward Massage Therapy Guidelines: A First Report to the Profession

    PubMed Central

    Grant, Keith Eric; Balletto, John; Gowan-Moody, Donelda; Healey, Dale; Kincaid, Diana; Lowe, Whitney; Travillian, Ravensara S.

    2008-01-01

    The massage profession has grown rapidly since the late 1980s. As with business startups that begin informally and successfully mature into larger enterprises, growth brings new organizational challenges, together with greater visibility and opportunity. The maturation of massage as a health care profession increases the need for a process to formalize the synthesis of massage therapy knowledge from clinical experience and research—to collect what we know and to make such baseline knowledge widely available to practitioners, consumers, and other health care stakeholders. In short, we need to create a process for setting guidelines. The present paper lays out the motivations and framework for creating massage therapy guidelines that are informed both by research and by clinical experience. It also acts as a report to the massage therapy profession and to other stakeholders about the work of the Best Practices Committee of the Massage Therapy Foundation since 2006. And it has the additional goal of providing a health care literature basis for future academic discussions of massage. The discussion here is based on a definition from the Institute of Medicine and on research into the nature of expertise. Guidelines are targeted for submission to the National Guideline Clearinghouse. Challenges in creating guidelines for massage therapy are discussed. Various stakeholders are considered. Current literature from the wider scope of health care is extensively reviewed. Topics addressed include guideline creation, credentialing of complementary and alternative medicine practitioners, definition of competence, and the increasing role of technology (that is, informatics) in managing training and task-necessary competencies. Finally, a process for creation of massage therapy guidelines is proposed. A central feature of the proposal is the use of a “World Café” symposium to elicit knowledge and solutions from diverse experts. The role of transparency and broad and open peer review is emphasized as essential to the usability and credibility of guidelines. PMID:21589815

  20. Steps toward massage therapy guidelines: a first report to the profession.

    PubMed

    Grant, Keith Eric; Balletto, John; Gowan-Moody, Donelda; Healey, Dale; Kincaid, Diana; Lowe, Whitney; Travillian, Ravensara S

    2008-08-20

    The massage profession has grown rapidly since the late 1980s. As with business startups that begin informally and successfully mature into larger enterprises, growth brings new organizational challenges, together with greater visibility and opportunity. The maturation of massage as a health care profession increases the need for a process to formalize the synthesis of massage therapy knowledge from clinical experience and research-to collect what we know and to make such baseline knowledge widely available to practitioners, consumers, and other health care stakeholders. In short, we need to create a process for setting guidelines.The present paper lays out the motivations and framework for creating massage therapy guidelines that are informed both by research and by clinical experience. It also acts as a report to the massage therapy profession and to other stakeholders about the work of the Best Practices Committee of the Massage Therapy Foundation since 2006. And it has the additional goal of providing a health care literature basis for future academic discussions of massage.The discussion here is based on a definition from the Institute of Medicine and on research into the nature of expertise. Guidelines are targeted for submission to the National Guideline Clearinghouse. Challenges in creating guidelines for massage therapy are discussed. Various stakeholders are considered. Current literature from the wider scope of health care is extensively reviewed. Topics addressed include guideline creation, credentialing of complementary and alternative medicine practitioners, definition of competence, and the increasing role of technology (that is, informatics) in managing training and task-necessary competencies. Finally, a process for creation of massage therapy guidelines is proposed. A central feature of the proposal is the use of a "World Café" symposium to elicit knowledge and solutions from diverse experts. The role of transparency and broad and open peer review is emphasized as essential to the usability and credibility of guidelines.

  1. 3D printing of bacteria into functional complex materials.

    PubMed

    Schaffner, Manuel; Rühs, Patrick A; Coulter, Fergal; Kilcher, Samuel; Studart, André R

    2017-12-01

    Despite recent advances to control the spatial composition and dynamic functionalities of bacteria embedded in materials, bacterial localization into complex three-dimensional (3D) geometries remains a major challenge. We demonstrate a 3D printing approach to create bacteria-derived functional materials by combining the natural diverse metabolism of bacteria with the shape design freedom of additive manufacturing. To achieve this, we embedded bacteria in a biocompatible and functionalized 3D printing ink and printed two types of "living materials" capable of degrading pollutants and of producing medically relevant bacterial cellulose. With this versatile bacteria-printing platform, complex materials displaying spatially specific compositions, geometry, and properties not accessed by standard technologies can be assembled from bottom up for new biotechnological and biomedical applications.

  2. Acknowledging the Elephant in the Room: How Stressful Environmental Contexts Shape Relationship Dynamics

    PubMed Central

    Neff, Lisa A.; Karney, Benjamin R.

    2016-01-01

    Compared to affluent marriages, lower income marriages develop within a context filled with negative stressors that may prove quite toxic for marital stability. The current paper argues that stressful contexts may undermine marital well-being through two routes. First, external stressors create additional problems within the marriage by diverting time and attention away from activities that promote intimacy between partners. Second, external stress may render spouses ill-equipped to cope with this increase in problems by draining spouses of the energy and resources necessary for responding to marital challenges in a constructive manner. In acknowledging the role of the marital context for relationship dynamics, this model suggests new directions for interventions designed to strengthen the marriages of lower income couples. PMID:27766285

  3. [Activities using websites and social networks: tools and indicators for evaluation].

    PubMed

    López, María José; Continente, Xavier; Sánchez, Esther; Bartroli, Montse

    In the field of health, information and communication technology (ICT) can create a space that, regardless of place or time, enables information to be shared and disseminated quickly. In addition to the usual challenges of evaluating public health activities, other difficulties are present when evaluating activities using ICT, such as lack of previous standards, unknown individual exposure or lack of information on the characteristics of those exposed. The aim of this paper is to describe some tools and indicators that may help to assess the scope, use and parameters related to website positioning on search engines as well as the connected social networks. Copyright © 2017 SESPAS. Publicado por Elsevier España, S.L.U. All rights reserved.

  4. 3D printing of bacteria into functional complex materials

    PubMed Central

    Schaffner, Manuel; Rühs, Patrick A.; Coulter, Fergal; Kilcher, Samuel; Studart, André R.

    2017-01-01

    Despite recent advances to control the spatial composition and dynamic functionalities of bacteria embedded in materials, bacterial localization into complex three-dimensional (3D) geometries remains a major challenge. We demonstrate a 3D printing approach to create bacteria-derived functional materials by combining the natural diverse metabolism of bacteria with the shape design freedom of additive manufacturing. To achieve this, we embedded bacteria in a biocompatible and functionalized 3D printing ink and printed two types of “living materials” capable of degrading pollutants and of producing medically relevant bacterial cellulose. With this versatile bacteria-printing platform, complex materials displaying spatially specific compositions, geometry, and properties not accessed by standard technologies can be assembled from bottom up for new biotechnological and biomedical applications. PMID:29214219

  5. The UNAM M. Sc. program in Medical Physics enters its teen years

    NASA Astrophysics Data System (ADS)

    Brandan, María-Ester

    2010-12-01

    The M.Sc. (Medical Physics) program at the National Autonomous University of Mexico UNAM, created in 1997, has graduated a substantial number of medical physicists who constitute today about 30% of the medical physics clinical workforce in the country. Up to present date (May 2010) more than 60 students have graduated, 60% of them hold clinical jobs, 20% have completed or study a Ph.D., and 15% perform activities related to this specialization. In addition to strengthening the clinical practice of medical physics, the program has served as an incentive for medical physics research in UNAM and other centers. We report the circumstances of the program origin, the evolution of its curriculum, the main achievements, and the next challenges.

  6. The frail elderly: a matter of caring.

    PubMed

    Erlen, Judith A

    2007-01-01

    Nurses caring for patients with orthopaedic problems often encounter elderly patients in their caseload. These patients have variable levels of functioning; some may be frail and, therefore, require greater assistance and possibly more time with their care. This loss of function and need for more assistance increases their vulnerability and creates challenges for nurses and other healthcare providers who are delivering patient care. This article offers a brief description of the frail elderly and examines their increasing vulnerability and their need for additional protection, preserving their dignity and respecting their autonomy, and how caring helps to guide nurses in addressing the special needs of this particularly vulnerable patient population. Sensitivity, patience, trust, compassion, and clinical competence matter when caring for the frail elderly.

  7. Sorting Tasks and Vocabulary-in-Context Activities for Assessing Introductory Astronomy Understanding

    NASA Astrophysics Data System (ADS)

    Slater, Timothy F.; Loranz, D.; Prather, E. E.

    2006-12-01

    One of the most ardent challenges for astronomy teachers is to deeply and meaningfully assess students’ conceptual and quantitative understanding of astronomy topics. In an effort to uncover students’ actual understanding, members and affiliates of the Conceptual Astronomy and Physics Education Research (CAPER) Team at the University of Arizona and Truckee Meadows Community College are creating and field-testing innovative approaches to assessment. Leveraging from the highly successful work from physics education research, we are creating a series of tasks where students categorize a list describing common astronomical events or phenomenon; or vocabulary terms into context rich categories or conceptually rich sentences. These intellectually challenging tasks are being created to span the entire domain of topics in introductory astronomy for non-science majoring undergraduates. When completed, these sorting tasks and vocabulary-in-context activities will be able to be delivered via a drag-and-drop computer interface.

  8. Visual Activities for Assessing Non-science Majors’ Understanding in Introductory Astronomy

    NASA Astrophysics Data System (ADS)

    Loranz, Daniel; Prather, E. E.; Slater, T. F.

    2006-12-01

    One of the most ardent challenges for astronomy teachers is to deeply and meaningfully assess students’ conceptual and quantitative understanding of astronomy topics. In an effort to uncover students’ actual understanding, members and affiliates of the Conceptual Astronomy and Physics Education Research (CAPER) Team at the University of Arizona and Truckee Meadows Community College are creating and field-testing innovative approaches to assessment. Leveraging from the highly successful work on interactive lecture demonstrations from astronomy and physics education research, we are creating a series of conceptually rich questions that are matched to visually captivating and purposefully interactive astronomical animations. These conceptually challenging tasks are being created to span the entire domain of topics in introductory astronomy for non-science majoring undergraduates. When completed, these sorting tasks and vocabulary-in-context activities will be able to be delivered via a drag-and-drop computer interface.

  9. Multiple Sclerosis in the Contemporary Age: Understanding the Millennial Patient with Multiple Sclerosis to Create Next-Generation Care.

    PubMed

    Hansen, Madison R; Okuda, Darin T

    2018-02-01

    The average age of onset of multiple sclerosis (MS) is between 20 and 40 years of age. Therefore, most new patients diagnosed with MS within the next 10 to 15 years will be from the millennial generation, representing those born between 1982 and 2000. Certain preferences and trends of this contemporary generation will present new challenges to the MS physician and effective MS care. By first understanding these challenges, relevant and successful solutions can be created to craft a system of care that best benefits the millennial patient with MS. Copyright © 2017 Elsevier Inc. All rights reserved.

  10. Crowdsourcing biomedical research: leveraging communities as innovation engines

    PubMed Central

    Saez-Rodriguez, Julio; Costello, James C.; Friend, Stephen H.; Kellen, Michael R.; Mangravite, Lara; Meyer, Pablo; Norman, Thea; Stolovitzky, Gustavo

    2018-01-01

    The generation of large-scale biomedical data is creating unprecedented opportunities for basic and translational science. Typically, the data producers perform initial analyses, but it is very likely that the most informative methods may reside with other groups. Crowdsourcing the analysis of complex and massive data has emerged as a framework to find robust methodologies. When the crowdsourcing is done in the form of collaborative scientific competitions, known as Challenges, the validation of the methods is inherently addressed. Challenges also encourage open innovation, create collaborative communities to solve diverse and important biomedical problems, and foster the creation and dissemination of well-curated data repositories. PMID:27418159

  11. Crowdsourcing biomedical research: leveraging communities as innovation engines.

    PubMed

    Saez-Rodriguez, Julio; Costello, James C; Friend, Stephen H; Kellen, Michael R; Mangravite, Lara; Meyer, Pablo; Norman, Thea; Stolovitzky, Gustavo

    2016-07-15

    The generation of large-scale biomedical data is creating unprecedented opportunities for basic and translational science. Typically, the data producers perform initial analyses, but it is very likely that the most informative methods may reside with other groups. Crowdsourcing the analysis of complex and massive data has emerged as a framework to find robust methodologies. When the crowdsourcing is done in the form of collaborative scientific competitions, known as Challenges, the validation of the methods is inherently addressed. Challenges also encourage open innovation, create collaborative communities to solve diverse and important biomedical problems, and foster the creation and dissemination of well-curated data repositories.

  12. How Mockups, a Key Engineering Tool, Help to Promote Science, Technology, Engineering, and Mathematics Education

    NASA Technical Reports Server (NTRS)

    McDonald, Harry E.

    2010-01-01

    The United States ranking among the world in science, technology, engineering, and mathematics (STEM) education is decreasing. To counteract this problem NASA has made it part of its mission to promote STEM education among the nation s youth. Mockups can serve as a great tool when promoting STEM education in America. The Orion Cockpit Working Group has created a new program called Students Shaping America s Next Space Craft (SSANS) to outfit the Medium Fidelity Orion Mockup. SSANS will challenge the students to come up with unique designs to represent the flight design hardware. There are two main types of project packages created by SSANS, those for high school students and those for university students. The high school projects will challenge wood shop, metal shop and pre-engineering classes. The university projects are created mainly for senior design projects and will require the students to perform finite element analysis. These projects will also challenge the undergraduate students in material selection and safety requirements. The SSANS program will help NASA in its mission to promote STEM education, and will help to shape our nations youth into the next generation of STEM leaders.

  13. ALLOCATING ENVIRONMENTAL BURDENS ACROSS CO-PRODUCTS TO CREATE A LIFE CYCLE INVENTORY: IS THERE A BEST WAY?

    EPA Science Inventory

    Allocation methodology for creating life cycle inventories is frequently addressed, discussed and debated, yet the methodology continues to be in a state of flux. ISO 14041 puts perspective on the issues but its one-size fits all framework is being challenged. It is clear that ...

  14. Scholarship: The Key to Creating Change through Outreach

    ERIC Educational Resources Information Center

    Bruns, Karen; Conklin, Nikki; Wright, Mindy; Hoover, David; Brace, Ben; Wise, Greg; Pendleton, Fariba; Dann, Michael; Martin, Michael; Childers, Jeri

    2002-01-01

    Outreach can and should exemplify the characteristics typical of any scholarly work if it is to create change in our communities and universities. Glassick, Huber, and Maeroff's insight on the standards for scholarly work are reflected in the processes commonly used to implement outreach. Boyer challenges us to think of scholarship as a communal…

  15. Panel Discussion: Creating a Spirit of Inquiry in the Classroom

    ERIC Educational Resources Information Center

    Leh, Sandra Kundrik; Melincavage, Sharon M.

    2012-01-01

    A paucity of published literature exists related to the use of panel discussion as a teaching strategy. This article describes the panel discussion, the underpinnings of constructivism and the use of panel discussion to create a constructivist classroom environment. Details of planning, evaluating, and challenges of a panel discussion are also…

  16. Issues and Options in Creating a National Assessment in World History

    ERIC Educational Resources Information Center

    Bain, Robert B.; Shreiner, Tamara L.

    2005-01-01

    The National Assessment Governing Board (NAGB) is considering creating a National Assessment of Educational Progress (NAEP) for world history education. On the surface, a national assessment in world history appears to be a sensible and essentially unproblematic decision. However, problems lurk below the surface challenging the creation of a…

  17. An Interdisciplinary Design Project in Second Life: Creating a Virtual Marine Science Learning Environment

    ERIC Educational Resources Information Center

    Triggs, Riley; Jarmon, Leslie; Villareal, Tracy A.

    2010-01-01

    Virtual environments can resolve many practical and pedagogical challenges within higher education. Economic considerations, accessibility issues, and safety concerns can all be somewhat alleviated by creating learning activities in a virtual space. Because of the removal of real-world physical limitations like gravity, durability and scope,…

  18. A Sales Representative Is Made: An Innovative Sales Course

    ERIC Educational Resources Information Center

    Levin, Michael A.; Peterson, Lori T.

    2016-01-01

    Job openings for nonscientific business-to-business sales professionals will increase over the next 10 years. A small private university in the Midwest has developed an innovative sales course to help create professionals who are ready to fill this need. This article addresses the challenges of creating a meaningful, hands-on, experiential course…

  19. Renaissance Schools Fund-Supported Schools: Early Outcomes, Challenges, and Opportunities

    ERIC Educational Resources Information Center

    Young, Viki M.; Humphrey, Daniel C.; Wang, Haiwen; Bosetti, Kristin R.; Cassidy, Lauren; Wechsler, Marjorie E.; Rivera, Elizabeth; Murray, Samantha; Schanzenbach, Diane Whitmore

    2009-01-01

    Chicago's Renaissance 2010 seeks to create 100 new and autonomous schools by 2010. These new schools are expected to increase choice for parents and students, enact innovative practices, and help create a portfolio of schools designed to make the Chicago Public Schools (CPS) more diversified, responsive, and effective. Renaissance Schools Fund…

  20. Helping Students Rise and Shine

    ERIC Educational Resources Information Center

    Ross, Flynn; Gendron, Marcia; Nogar, Dan; Queen, Marjorie

    2018-01-01

    A high-poverty, previously low-performing elementary school in Maine shifted its from looking mainly at achievement and test scores to focusing on ways to create motivated, confident, engaged students. They created Rise and Shine, through which all 3rd-5th graders start each day with a fun, challenging activity chosen from a big menu--from…

  1. A Pilot Evaluation of Using Symbol-Based Information in Police Custody

    ERIC Educational Resources Information Center

    Parsons, Sarah; Sherwood, Gina

    2016-01-01

    At least 20-30% of offenders within the criminal justice system (CJS) have learning disabilities or difficulties. This creates significant challenges in relation to meeting their information needs about rights, entitlements, processes and procedures. We report a pilot project where widgit Symbols were used to create more accessible information…

  2. Managing agricultural emissions to the atmosphere: State of the science, fate and mitigation, and identifying research gaps

    USDA-ARS?s Scientific Manuscript database

    The impact of agriculture on regional air quality creates significant challenges to sustainability of food supplies and to the quality of national resources. Agricultural emissions to the atmosphere can lead to many nuisances, such as smog, haze, or offensive odors. They can also create more seriou...

  3. Learning and Organizational Effectiveness: A Systems Perspective

    ERIC Educational Resources Information Center

    Andreadis, Nicholas

    2009-01-01

    The challenge for leaders today is to create and develop the capability of their organization. Leaders must perceive and manage their organization as a dynamic, open system where learning is the core competence underlying innovation, growth, and sustainability. Creating a culture of learning is the first work of leadership. This article presents a…

  4. Opting Out: Parents Creating Contested Spaces to Challenge Standardized Tests

    ERIC Educational Resources Information Center

    Mitra, Dana; Mann, Bryan; Hlavacik, Mark

    2016-01-01

    We explore how the opt-out movement has responded to the combination of a stringent federal policy with weak and often variable implementation among the states. Gaps between federal expectations and states' understandings of just how to make NCLB's demands a reality have created policy ambiguity. Parents who oppose standardized testing have…

  5. Reconsidering Differential Behaviors: Reflection and Teacher Judgment When Forming Classroom Relationships

    ERIC Educational Resources Information Center

    Newberry, Melissa

    2013-01-01

    Positive teacher-student relationships promote growth in students both academically and socially, but in today's ever-changing classrooms creating such positive relationships can be a challenge. This study attempts to look at the influences on teacher thinking and judgment when creating and maintaining relationships. This is done by examining the…

  6. Creating Next Generation Blended Learning Environments Using Mixed Reality, Video Games and Simulations

    ERIC Educational Resources Information Center

    Kirkley, Sonny E.; Kirkley, Jamie R.

    2005-01-01

    In this article, the challenges and issues of designing next generation learning environments using current and emerging technologies are addressed. An overview of the issues is provided as well as design principles that support the design of instruction and the overall learning environment. Specific methods for creating cognitively complex,…

  7. Facilitating Interdisciplinary Work: Using Quality Assessment to Create Common Ground

    ERIC Educational Resources Information Center

    Oberg, Gunilla

    2009-01-01

    Newcomers often underestimate the challenges of interdisciplinary work and, as a rule, do not spend sufficient time to allow them to overcome differences and create common ground, which in turn leads to frustration, unresolved conflicts, and, in the worst case scenario, discontinued work. The key to successful collaboration is to facilitate the…

  8. Personalizing the Scholarship of Teaching and Learning: A 2001-2002 Carnegie Scholars Project Report.

    ERIC Educational Resources Information Center

    Gayle, Barbara Mae

    Societal acceptance of polarized discourse poses challenges for communication professors engaged in teaching ethical public speaking processes to undergraduates. This study explores how creating caring and safe environments for the discussion of difficult dialogues is paramount to creating civil and reasoned discourse that can address issues of…

  9. Creating Start-up Companies around NCI Inventions | Poster

    Cancer.gov

    By Karen Surabian, Thomas Stackhouse, and Rose Freel, Contributing Writers, and Rosemarie Truman, Guest Writer The National Cancer Institute (NCI), led by the Technology Transfer Center (TTC),  the Avon Foundation, and The Center for Advancing Innovation have partnered to create a “first-of-a-kind” Breast Cancer Start-up Challenge.

  10. The Canon, the Web, and the Long Tail

    ERIC Educational Resources Information Center

    Sanderhoff, Merete

    2017-01-01

    This article argues that releasing images of artworks into the public domain creates a new possibility for the public to challenge the canon or create their own, based on access to previously inaccessible images. Through the dissemination of openly licensed artworks across the Internet, museums can support the public in expanding their engagement…

  11. Clinical Epidemiology (CE) and Evidence-Based Medicine (EBM) in the Asia Pacific region (Round Table Forum).

    PubMed

    Su, Tin Tin; Bulgiba, Awang M; Sampatanukul, Pichet; Sastroasmoro, Sudigdo; Chang, Peter; Tharyan, Prathap; Lin, Vivian; Wong, Yut Lin

    2013-01-01

    Clinical Epidemiology (CE) and Evidence-Based Medicine (EBM) have become increasingly important in an era of rising costs, patient safety concerns and evidence-based health care. CE and EBM research in the Asia Pacific region have grown significantly. However, there are three main challenges such as linking evidence to practice and policy; developing a strong collaborative network; and a need for resources and technical expertise to produce evidence. The Cochrane Collaboration is a possible solution to resolve above challenges identified, particularly the challenge of transforming evidence to practice. In addition, training can be carried out to enhance technical expertise in the region and there is also the promising potential that collaborations could extend beyond systematic reviews. To improve the adoption of evidence-based health policy, selection of the best evidence for the right audience and focusing on the relevant issues through appropriate methodology are essential. Information on effectiveness and cost effectiveness needs to be highlighted for policy makers. The way forward to strengthen research and capacity building is to establish the Asia Pacific Consortium for CE and EBM. The consortium would help to create mutually rewarding scientific research and collaborations that will augur well for advances in CE and EBM. Copyright © 2013 Elsevier Inc. All rights reserved.

  12. Updates on Managing Type 2 Diabetes Mellitus with Natural Products: Towards Antidiabetic Drug Development.

    PubMed

    Alam, Fahmida; Islam, Md Asiful; Kamal, M A; Gan, Siew Hua

    2016-08-13

    Over the years, natural products have shown success as antidiabetics in vitro, in vivo and in clinical trials. Because natural product-derived drugs are more affordable and effective with fewer side-effects compared to conventional therapies, pharmaceutical research is increasingly leaning towards the discovery of new antidiabetic drugs from natural products targeting pathways or components associated with type 2 diabetes mellitus (T2DM) pathophysiology. However, the drug discovery process is very lengthy and costly with significant challenges. Therefore, various techniques are currently being developed for the preclinical research phase of drug discovery with the aim of drug development with less time and efforts from natural products. In this review, we have provided an update on natural products including fruits, vegetables, spices, nuts, beverages and mushrooms with potential antidiabetic activities from in vivo, in vitro and clinical studies. Synergistic interactions between natural products and antidiabetic drugs; and potential antidiabetic active compounds from natural products are also documented to pave the way for combination treatment and new drug discovery, respectively. Additionally, a brief idea of the drug discovery process along with the challenges that arise during drug development from natural products and the methods to conquer those challenges are discussed to create a more convenient future drug discovery process.

  13. Where to next with animal health in Latin America? The transition from endemic to disease-free status.

    PubMed

    Rojas, H; Romero, J R

    2017-04-01

    The Latin American and Caribbean region (LAC) is a leading global producer and exporter of animal products. Its livestock production systems are diverse, ranging from large-scale commercial enterprises to family farms. Countries in this region have sought to improve their animal health status through both public and private efforts. Despite significant advances in eradicating such diseases as foot and mouth disease and classical swine fever, other animal health challenges remain; constraining exports, causing negative economic impacts and threatening food security. Obtaining certification of disease-free status is only the first step towards gaining benefits from improvements in animal health. Increasing international trade means that countries must manage the sustainability of their disease-free status in conjunction with trade partners and must comply with additional food safety and animal welfare standards. This paper comments on the challenges created by this new scenario in relation to the epidemiology and economics of animal health, when seeking to improve decisionmaking for animal health management. The authors characterise the current LAC livestock landscape and animal health situation, describing transitions in disease control and the use of economics in improving animal health. They conclude with remarks on the challenges presented by decision-making, economic rationality, sources of benefits, distribution and incentives.

  14. Thinking, feeling and moving: drama and movement therapy as an adjunct to a multidisciplinary rehabilitation approach for chronic pain in two adolescent girls.

    PubMed

    Christie, Deborah; Hood, Deborah; Griffin, Angela

    2006-10-01

    Chronic Pain without an identifiable organic basis represents a substantial element of referrals to both medical and mental health professionals. Chronic pain can compromise independence, school attendance, physical and social activities. The tendency to label 'nonorganic' pain as having a psychological origin is usually strongly resisted by parents and young people with treatment creating a significant challenge for health care professionals. Collaborative, multidisciplinary treatment programmes encourage families to find ways of getting on with their lives by taking a proactive approach to challenging pain. The family is invited to join with the team in the task of challenging the pain through the use of physiotherapy to increase strength, stamina and suppleness alongside a range of individual and group activities that can include relaxation training, hypnotherapy, systemic and cognitive-behavioural approaches. This article describes how drama and movement therapy was introduced as an additional component of the treatment programme of two adolescents who had been long-term inpatients on a medical adolescent ward. The experiences of adding a complementary therapy to the programme are described to illustrate a creative way of contributing to established treatment programmes through the use of sound, movement and gesture in order to provide a space to explore new ways of being and expanding abilities.

  15. Strategies for Building Positive Student-Instructor Interactions in Large Classes

    ERIC Educational Resources Information Center

    Solis, Oscar J.; Turner, Windi D.

    2016-01-01

    Although large classes in and of themselves are pragmatic for universities, they can be challenging for both students and instructors. The purpose of this study was to investigate pedagogical strategies that instructors teaching large classes can utilize to create positive student-instructor interactions to counter these challenges. Both…

  16. Strategies, Challenges and Prospects for Active Learning in the Computer-Based Classroom

    ERIC Educational Resources Information Center

    Holbert, K. E.; Karady, G. G.

    2009-01-01

    The introduction of computer-equipped classrooms into engineering education has brought with it a host of opportunities and issues. Herein, some of the challenges and successes for creating an environment for active learning within computer-based classrooms are described. The particular teaching approach developed for undergraduate electrical…

  17. Taking a Community Approach to Curriculum Change

    ERIC Educational Resources Information Center

    Dalrymple, Sarah E.; Auerbach, Anna Jo; Schussler, Elisabeth E.

    2017-01-01

    Many undergraduate institutions are reforming their courses to increase student engagement. A critical challenge in these efforts is to engage the academic community beyond the instructors in the process of change. At our university, we embraced this challenge by creating a volunteer community of faculty, postdocs, graduate students, and…

  18. Combating Ethical Issues in University Admissions Using Technology

    ERIC Educational Resources Information Center

    George, Micael S., Jr.; Soares, Caio V.; Gilbert, Juan E.

    2009-01-01

    Obtaining diversity among admitted applicants is often a challenging task for most post secondary institutions. As a proposed solution to this challenge, Applications Quest (AQ) was created. AQ addresses the dilemma of how to achieve diversity while still upholding institutional academic standards and objectives while adhering to the law. A steady…

  19. Challenges in Archetypes Terminology Binding Using SNOMED-CT Compositional Grammar: The Norwegian Patient Summary Case.

    PubMed

    Marco-Ruiz, Luis; Pedersen, Rune

    2017-01-01

    In order to cover the requirements for interoperability in the Norwegian context, we studied the terminology binding of archetypes to terminology expressions created with the SNOMED-CT compositional grammar. As a result we identified important challenges categorized as technical, expressivity, human, and models mismatch.

  20. Challenges and Strategies for Assessing Specialised Knowledge for Teaching

    ERIC Educational Resources Information Center

    Orrill, Chandra Hawley; Kim, Ok-Kyeong; Peters, Susan A.; Lischka, Alyson E.; Jong, Cindy; Sanchez, Wendy B.; Eli, Jennifer A.

    2015-01-01

    Developing and writing assessment items that measure teachers' knowledge is an intricate and complex undertaking. In this paper, we begin with an overview of what is known about measuring teacher knowledge. We then highlight the challenges inherent in creating assessment items that focus specifically on measuring teachers' specialised knowledge…

  1. Relative Harmony: Achieving Balance in Your Brand Family

    ERIC Educational Resources Information Center

    Collins, Mary Ellen

    2011-01-01

    Educational institutions understand the importance of having a positive image among their target audiences, but the process of creating, enhancing, and managing that image remains challenging to many. Confusion over what branding is only adds to the challenge. Consultants define "brand" as promising an experience and delivering on that…

  2. Curriculum Change and Climate Change: Inside outside Pressures in Higher Education

    ERIC Educational Resources Information Center

    Fahey, Shireen J.

    2012-01-01

    In higher education today, institutions are facing a number of challenges--including the challenge to create future-proof graduates. Higher education institutions have a particular mandate to develop future leaders and decision-makers capable of understanding and providing solutions to complex, global issues. Education programmes that focus on…

  3. Addressing a Nation's Challenge: Graduate Programs in Gerontology in Israel

    ERIC Educational Resources Information Center

    Carmel, Sara; Lowenstein, Ariela

    2007-01-01

    Like other developed nations, Israel has rapidly aged. This demographic revolution has created new challenges for Israeli society. We describe the societal background, including the emerging societal needs, solutions, and problems, as well as the professional principles, which guided us in developing the first two Israeli academic programs in…

  4. Challenge Beginning Teacher Beliefs

    ERIC Educational Resources Information Center

    Lannin, John K.; Chval, Kathryn B.

    2013-01-01

    As beginning teachers start to recognize the complexity of teaching mathematics in elementary school classrooms and how their new vision for teaching mathematics creates new challenges, they experience discomfort--a healthy awareness that much is to be learned. Brousseau (1997) notes that changes in the roles that are implicitly assigned to the…

  5. Teaching Racism: Using Experiential Learning to Challenge the Status Quo

    ERIC Educational Resources Information Center

    Loya, Melody Aye; Cuevas, Mo

    2010-01-01

    Teaching about racism creates challenging issues for educators and students alike. Using experiential learning and a public-access curriculum to teach about racism and social inequality, graduate and undergraduate students participated in this elective course. The hybrid "minimester" course focused on affective responses to classroom activities,…

  6. Forging University-Community Collaboration: The Agency Perspective on National Service.

    ERIC Educational Resources Information Center

    Tice, Carol H.

    1994-01-01

    With passage of the National and Community Service Trust Act of 1993, national service volunteers will be joining forces with community-based organizations to work with underserved populations, creating many challenges. The community agency perspective on some anticipated challenges, possible responses, and application of principles of good…

  7. The Clay Challenge Continues...

    ERIC Educational Resources Information Center

    Coy, Mary

    2007-01-01

    It was time for yet another challenge. Bright colored glazes were on hiatus; earth tones and mixed media took center stage. Inspiration was provided this time by the myriad Native American potters from the desert Southwest. The project: create a coil pot that demonstrates interesting form and good artistry and reflects, through symbolism or mixed…

  8. The Challenge. Volume 13, Number 3, Spring 2005

    ERIC Educational Resources Information Center

    US Department of Education, 2005

    2005-01-01

    "The Challenge", a publication of the US Department of Education's office of Safe and Drug-Free Schools, provides critical information and resources to assist schools in creating safe and healthy environments for young people. This issue addresses the following topics: (1) Prevention Programs with Staying Power: What Makes Good Prevention Programs…

  9. The Challenge. Volume 14, Number 3

    ERIC Educational Resources Information Center

    US Department of Education, 2007

    2007-01-01

    "The Challenge" provides information and resources to help schools create safe and healthy learning environments for students. Articles in this issue include: (1) Research Shows Consequences of Drug Abuse on the Teenage Brain (Don Vereen); (2) Interview: NIDA [National Institute on Drug Abuse] Director Discusses Drug Abuse among Teens; (3) Know…

  10. Districtwide Instructional Reform: Using Sociocultural Theory to Link Professional Learning to Organizational Support

    ERIC Educational Resources Information Center

    Gallucci, Chrysan

    2008-01-01

    No Child Left Behind Act accountability pressures and calls to close achievement gaps between groups of students have challenged school districts to achieve systemwide instructional improvement. These policies create learning challenges for classroom teachers and for school and district leaders. This article engages questions about organizational…

  11. Redesigning State Financial Aid: Principles to Guide State Aid Policymaking

    ERIC Educational Resources Information Center

    Pingel, Sarah; Sponsler, Brian A.

    2015-01-01

    Several factors create a challenging environment for individuals seeking financial support to complete a postsecondary degree program. In recognition of the challenges of paying for higher education, decision-makers at the federal and state levels support college-going with public policy. Through direct institutional allocations, need and…

  12. Addressing Diversity on College Campuses: Changing Expectations and Practices in Instructional Leadership

    ERIC Educational Resources Information Center

    Chen, Angela

    2017-01-01

    The increasing diversity evident across all facets of American society is creating opportunities as well as challenges for instructional leaders across the nation's postsecondary institutions. Racial and ethnic diversity and the attendant challenges and benefits of multiculturalism in society are more awareness in higher education. This study…

  13. The Development and Implementation of Outdoor-Based Secondary School Integrated Programs

    ERIC Educational Resources Information Center

    Comishin, Kelly; Dyment, Janet E.; Potter, Tom G.; Russell, Constance L.

    2004-01-01

    Four teachers share the challenges they faced when creating and running outdoor-focused secondary school integrated programs in British Columbia, Canada. The five most common challenges were funding constraints, insufficient support from administrators and colleagues, time constraints, liability and risk management, and inadequate skills and…

  14. Facing the Issues: Challenges, Censorship, and Reflection through Dialogue

    ERIC Educational Resources Information Center

    Lent, ReLeah Cossett

    2008-01-01

    ReLeah Cossett Lent provides practical advice for ensuring that books are kept on shelves and in classrooms for students to read. She outlines steps for creating professional learning communities that engage with censorship issues and prepare schools to deal with book challenges in thoughtful, supportive ways. (Contains 4 figures.)

  15. Choosing High-Yield Tasks for the Mathematical Development of Practicing Secondary Teachers

    ERIC Educational Resources Information Center

    Epperson, James A. Mendoza; Rhoads, Kathryn

    2015-01-01

    Many mathematics teacher educators encounter the challenge of creating or choosing mathematical tasks that evoke important mathematical insights and connections yet remain firmly grounded in school mathematics. This challenge increases substantially when trying to meet the needs of practicing secondary mathematics teachers pursuing graduate work…

  16. Creating Technology-Enriched Classrooms: Implementational Challenges in Turkish Education

    ERIC Educational Resources Information Center

    Kurt, Serhat

    2014-01-01

    This paper provides an overview of the status of educational technology in Turkey. In the face of severe social and economic challenges, many developing nations, including Turkey, are looking to education as a potential remedy. Recognizing that in an increasingly technology-dependent world, information and communications technology skills and…

  17. Learning the Language of Statistics: Challenges and Teaching Approaches

    ERIC Educational Resources Information Center

    Dunn, Peter K.; Carey, Michael D.; Richardson, Alice M.; McDonald, Christine

    2016-01-01

    Learning statistics requires learning the language of statistics. Statistics draws upon words from general English, mathematical English, discipline-specific English and words used primarily in statistics. This leads to many linguistic challenges in teaching statistics and the way in which the language is used in statistics creates an extra layer…

  18. Turning challenge into opportunity: what home care needs to know about Medicare advantage.

    PubMed

    Twiss, Amanda; Schwien, Tina

    2008-01-01

    With multiple payors having different rules, paperwork, and payment models, the challenge is that MA plans typically focus time and attention on the providers associated with the highest costs--hospitals and physicians. With little attention being paid to the home health providers, MA plans cost containment measures and operational practices create challenges for providers developing an overall treatment plan for a patient's episode of care.

  19. The practices, challenges and recommendations of South African audiologists regarding managing children with auditory processing disorders

    PubMed Central

    Govender, Samantha; Khan, Nasim

    2016-01-01

    Audiologists managing children with auditory processing disorders (APD) encounter challenges that include conflicting definitions, several classification profiles, problems with differential diagnosis and a lack of standardised guidelines. The heterogeneity of the disorder and its concomitant childhood disorders makes diagnosis difficult. Linguistic and cultural issues are additional challenges faced by South African audiologists. The study aimed to describe the practices, challenges and recommendations of South African audiologists managing children with APD. A quantitative, non-experimental descriptive survey was used to obtain data from 156 audiologists registered with the Health Professions of South Africa. Findings revealed that 67% screened for APD, 42% assessed while 43% provided intervention. A variety of screening and assessment procedures were being administered, with no standard test battery identified. A range of intervention strategies being used are discussed. When the relationship between the number of years of experience and the audiologists’ level of preparedness to practice in the field of APD was compared, a statistically significant difference (p = 0.049) was seen in that participants with more than 10 years of experience were more prepared to practice in this area. Those participants having qualified as speech-language therapists and audiologists were significantly more prepared (p = 0.03) to practice than the audiologists who comprised the sample. Challenges experienced by the participants included the lack of linguistically and culturally appropriate screening and assessment tools and limited normative data. Recommendations included reviewing the undergraduate audiology training programmes, reinstituting the South African APD Taskforce, developing linguistically and culturally appropriate normative data, creating awareness among educators and involving them in the multidisciplinary team. PMID:27380913

  20. Striving for a zero-error patient surgical journey through adoption of aviation-style challenge and response flow checklists: a quality improvement project.

    PubMed

    Low, Daniel K; Reed, Mark A; Geiduschek, Jeremy M; Martin, Lynn D

    2013-07-01

    We describe our aim to create a zero-error system in our pediatric ambulatory surgery center by employing effective teamwork and aviation-style challenge and response 'flow checklists' at key stages of the patient surgical journey. These are used in addition to the existing World Health Organization Surgical Safety Checklists (Ann Surg, 255, 2012 and 44). Bellevue Surgery Center is a freestanding ambulatory surgery center affiliated with Seattle Children's Hospital, WA, USA. Approximately three thousand ambulatory surgeries are performed each year across a variety of surgical disciplines. Key points in the patient surgical journey were identified as high risk (different time points from the WHO safer surgery checklists). These were moments when the team, patient, and equipment have to been reconfigured to maximize patient safety. These points were departure from induction room, arrival in the operating room, departure from operating room, and arrival in the postanesthesia care unit. Traditionally, the anesthesiologist has memorized a list of 'do-not-forget items' for each of these stages. We recognized the potential for error to occur if the process was solely the responsibility of one individual and their memory. So we created 'flow checklists' executed by the team at every one of these high-risk points. We adopted a challenge and response system for these flow checklists as this is a tried and tested system widely used in aviation for critical tasks such as configuring an aircraft pretakeoff and prelanding. A staff survey with a 72% response rate (n = 29) showed that the team valued the checklists and thought they contributed to patient safety. To date, we have had zero incidence of omitting any of the 24 items listed on the four flow checklists. We have created a reproducible model of care involving multiple checklists at high-risk points in the patient surgical journey. The model is reliable and has a high degree of staff engagement. It promotes patient safety by ensuring the patient, team and equipment are correctly configured at every key transition stage in the surgical journey. We have been able to achieve this with no measurable increase in turnover times or reduction in operating room efficiency. © 2013 John Wiley & Sons Ltd.

  1. Engineering-derived approaches for iPSC preparation, expansion, differentiation and applications.

    PubMed

    Li, Yang; Li, Ling; Chen, Zhi-Nan; Gao, Ge; Yao, Rui; Sun, Wei

    2017-07-31

    Remarkable achievements have been made since induced pluripotent stem cells (iPSCs) were first introduced in 2006. Compared with non-pluripotent stem cells, iPSC research faces several additional complexities, such as the choice of extracellular matrix proteins, growth and differentiation factors, as well as technical challenges related to self-renewal and directed differentiation. Overcoming these challenges requires the integration of knowledge and technologies from multiple fields including cell biology, biomaterial science, engineering, physics and medicine. Here, engineering-derived iPSC approaches are reviewed according to three aspects of iPSC studies: preparation, expansion, differentiation and applications. Engineering strategies, such as 3D systems establishment, cell-matrix mechanics and the regulation of biophysical and biochemical cues, together with engineering techniques, such as 3D scaffolds, cell microspheres and bioreactors, have been applied to iPSC studies and have generated insightful results and even mini-organs such as retinas, livers and intestines. Specific results are given to demonstrate how these approaches impact iPSC behavior, and related mechanisms are discussed. In addition, cell printing technologies are presented as an advanced engineering-derived approach since they have been applied in both iPSC studies and the construction of diverse tissues and organs. Further development and possible innovations of cell printing technologies are presented in terms of creating complex and functional iPSC-derived living tissues and organs.

  2. Gamifying quantum research: harnessing human intuition

    NASA Astrophysics Data System (ADS)

    Sherson, Jacob

    In the emerging field of citizen science ordinary citizens have already contributed to research in as diverse fields as astronomy, protein and RNA folding, and neuron mapping by playing online games. In the www.scienceathome.org project, we have extended this democratized research to the realm of quantum physics by gamifying a class of challenges related to optimization of gate operations in a quantum computer. The games have been played by more than 150,000 players and perhaps surprisingly we observe that a large fraction of the players outperform state-of-the-art optimization algorithms. With a palette of additional games within cognitive science, behavioral economics, and corporate innovation we investigate the general features of individual and collaborative problem solving to shed additional light on the process of human intuition and innovation and potentially develop novel models of artificial intelligence. We have also developed and tested in classrooms educational games within classical and quantum physics and mathematics at high-school and university level. The games provide individualized learning and enhance motivation for the core curriculum by actively creating links to modern research challenges, see eg. Finally, we have recently launched our new democratic lab: an easily accessible remote interface for our ultra-cold atoms experiment allowing amateur scientists, students, and research institutions world-wide to perform state-of-the-art quantum experimentation. In first tests, nearly a thousand players helped optimize the production of our BEC and discovered novel efficient strategies.

  3. Examining the need & potential for biomedical engineering to strengthen health care delivery for displaced populations & victims of conflict.

    PubMed

    Nadkarni, Devika; Elhajj, Imad; Dawy, Zaher; Ghattas, Hala; Zaman, Muhammad H

    2017-01-01

    Conflict and the subsequent displacement of populations creates unique challenges in the delivery of quality health care to the affected population. Equitable access to quality care demands a multi-pronged strategy with a growing need, and role, for technological innovation to address these challenges. While there have been significant contributions towards alleviating the burden of conflict via data informatics and analytics, communication technology, and geographic information systems, little has been done within biomedical engineering. This article elaborates on the causes for gaps in biomedical innovation for refugee populations affected by conflict, tackles preconceived notions, takes stock of recent developments in promising technologies to address these challenges, and identifies tangible action items to create a stronger and sustainable pipeline for biomedical technological innovation to improve the health and well-being of an increasing group of vulnerable people around the world.

  4. Ethical challenges in fetal surgery.

    PubMed

    Smajdor, Anna

    2011-02-01

    Fetal surgery has been practised for some decades now. However, it remains a highly complex area, both medically and ethically. This paper shows how the routine use of ultrasound has been a catalyst for fetal surgery, in creating new needs and new incentives for intervention. Some of the needs met by fetal surgery are those of parents and clinicians who experience stress while waiting for the birth of a fetus with known anomalies. The paper suggests that the role of technology and visualisation techniques in creating and meeting such new needs is ethically problematic. It then addresses the idea that fetal surgery should be restricted to interventions that are life-saving for the fetus, arguing that this restriction is unduly paternalistic. Fetal surgery poses challenges for an autonomy-based system of ethics. However, it is risky to circumvent these challenges by restricting the choices open to pregnant women, even when these choices appear excessively altruistic.

  5. Plain language: a strategic response to the health literacy challenge.

    PubMed

    Stableford, Sue; Mettger, Wendy

    2007-01-01

    Low health literacy is a major challenge confronting American and international health organizations. Research in the past decade has documented the prevalence of limited literacy and limited health literacy skills among adults worldwide. This creates a major policy challenge: how to create text-based health information - a common method of health communication - that is accessible to the public. Plain language is a logical, flexible response. While touted by American, Canadian, and European health policy makers, adoption and promotion of plain language standards and skills in health-focused organizations have lagged. Most text-based health information continues to be too hard for most adults to read. Barriers to more rapid diffusion of plain language are reflected in a set of myths perpetuated by critics. These myths are identified and refuted. While plain language is only one of many broad-based solutions needed to address low health literacy, the benefits to everyone demand increased use by health organizations.

  6. Creating Flexible and Sustainable Work Models for Academic Obstetrician-Gynecologists Engaged in Global Health Work.

    PubMed

    Molina, Rose; Boatin, Adeline; Farid, Huma; Luckett, Rebecca; Neo, Dayna; Ricciotti, Hope; Scott, Jennifer

    2017-10-01

    To describe various work models for obstetrics and gynecology global health faculty affiliated with academic medical centers and to identify barriers and opportunities for pursuing global health work. A mixed-methods study was conducted in 2016 among obstetrics and gynecology faculty and leaders from seven academic medical institutions in Boston, Massachusetts. Global health faculty members were invited to complete an online survey about their work models and to participate in semistructured interviews about barriers and facilitators of these models. Department chairs and residency directors were asked to participate in interviews. The survey response rate among faculty was 65.6% (21/32), of which 76.2% (16/21) completed an interview. Five department leaders (45.5% [5/11]) participated in an interview. Faculty described a range of work models with varied time and compensation, but only one third reported contracted time for global health work. The most common barriers to global health work were financial constraints, time limitations, lack of mentorship, need for specialized training, and maintenance of clinical skills. Career satisfaction, creating value for the obstetrics and gynecology department, and work model flexibility were the most important facilitators of sustainable global health careers. The study identified challenges and opportunities to creating flexible and sustainable work models for academic obstetrics and gynecology clinicians engaged in global health work. Additional research and innovation are needed to identify work models that allow for sustainable careers in global women's health. There are opportunities to create professional standards and models for academic global health work in the obstetrics and gynecology specialty.

  7. Creating Occupational Therapy: The Challenges to Defining a Profession.

    PubMed

    Reed, Kathlyn L

    2018-05-08

    The creation of a new profession in the early 20th century, such as occupational therapy, required a commitment to certain ideas and a willingness to accept certain challenges. This study examines the commitment to the idea of therapeutic and health supporting occupation by the early leaders and proponents of the profession and the challenges they faced in gaining acceptance of occupational therapy as a profession capable of delivering a valued health care service to society. Six challenges are reviewed as they occurred in the history of the profession and as they continue to challenge the profession into the present era.

  8. Strategies for medical data extraction and presentation part 2: creating a customizable context and user-specific patient reference database.

    PubMed

    Reiner, Bruce

    2015-06-01

    One of the greatest challenges facing healthcare professionals is the ability to directly and efficiently access relevant data from the patient's healthcare record at the point of care; specific to both the context of the task being performed and the specific needs and preferences of the individual end-user. In radiology practice, the relative inefficiency of imaging data organization and manual workflow requirements serves as an impediment to historical imaging data review. At the same time, clinical data retrieval is even more problematic due to the quality and quantity of data recorded at the time of order entry, along with the relative lack of information system integration. One approach to address these data deficiencies is to create a multi-disciplinary patient referenceable database which consists of high-priority, actionable data within the cumulative patient healthcare record; in which predefined criteria are used to categorize and classify imaging and clinical data in accordance with anatomy, technology, pathology, and time. The population of this referenceable database can be performed through a combination of manual and automated methods, with an additional step of data verification introduced for data quality control. Once created, these referenceable databases can be filtered at the point of care to provide context and user-specific data specific to the task being performed and individual end-user requirements.

  9. Chondrocytes and stem cells in 3D-bioprinted structures create human cartilage in vivo

    PubMed Central

    Amoroso, Matteo; Lindahl, Anders; Brantsing, Camilla; Rotter, Nicole; Gatenholm, Paul; Kölby, Lars

    2017-01-01

    Cartilage repair and replacement is a major challenge in plastic reconstructive surgery. The development of a process capable of creating a patient-specific cartilage framework would be a major breakthrough. Here, we described methods for creating human cartilage in vivo and quantitatively assessing the proliferative capacity and cartilage-formation ability in mono- and co-cultures of human chondrocytes and human mesenchymal stem cells in a three-dimensional (3D)-bioprinted hydrogel scaffold. The 3D-bioprinted constructs (5 × 5 × 1.2 mm) were produced using nanofibrillated cellulose and alginate in combination with human chondrocytes and human mesenchymal stem cells using a 3D-extrusion bioprinter. Immediately following bioprinting, the constructs were implanted subcutaneously on the back of 48 nude mice and explanted after 30 and 60 days, respectively, for morphological and immunohistochemical examination. During explantation, the constructs were easy to handle, and the majority had retained their macroscopic grid appearance. Constructs consisting of human nasal chondrocytes showed good proliferation ability, with 17.2% of the surface areas covered with proliferating chondrocytes after 60 days. In constructs comprising a mixture of chondrocytes and stem cells, an additional proliferative effect was observed involving chondrocyte production of glycosaminoglycans and type 2 collagen. This clinically highly relevant study revealed 3D bioprinting as a promising technology for the creation of human cartilage. PMID:29236765

  10. Chondrocytes and stem cells in 3D-bioprinted structures create human cartilage in vivo.

    PubMed

    Apelgren, Peter; Amoroso, Matteo; Lindahl, Anders; Brantsing, Camilla; Rotter, Nicole; Gatenholm, Paul; Kölby, Lars

    2017-01-01

    Cartilage repair and replacement is a major challenge in plastic reconstructive surgery. The development of a process capable of creating a patient-specific cartilage framework would be a major breakthrough. Here, we described methods for creating human cartilage in vivo and quantitatively assessing the proliferative capacity and cartilage-formation ability in mono- and co-cultures of human chondrocytes and human mesenchymal stem cells in a three-dimensional (3D)-bioprinted hydrogel scaffold. The 3D-bioprinted constructs (5 × 5 × 1.2 mm) were produced using nanofibrillated cellulose and alginate in combination with human chondrocytes and human mesenchymal stem cells using a 3D-extrusion bioprinter. Immediately following bioprinting, the constructs were implanted subcutaneously on the back of 48 nude mice and explanted after 30 and 60 days, respectively, for morphological and immunohistochemical examination. During explantation, the constructs were easy to handle, and the majority had retained their macroscopic grid appearance. Constructs consisting of human nasal chondrocytes showed good proliferation ability, with 17.2% of the surface areas covered with proliferating chondrocytes after 60 days. In constructs comprising a mixture of chondrocytes and stem cells, an additional proliferative effect was observed involving chondrocyte production of glycosaminoglycans and type 2 collagen. This clinically highly relevant study revealed 3D bioprinting as a promising technology for the creation of human cartilage.

  11. Ethical aspects of clinical research with minors.

    PubMed

    Bos, Wendy; Tromp, Krista; Tibboel, Dick; Pinxten, Wim

    2013-07-01

    Over the past decades, clinical research has increasingly been subjected to ethical requirements and legal regulation. The specific focus of ethical and legal frameworks on competent adults (which serve as the paradigmatic research subject), however, has created an ambivalent attitude towards pediatric clinical research. On one hand, minors are regarded as a vulnerable population that deserves additional protection against the risks and burdens involved in clinical research. On the other hand, the population of minors should not be denied (or not get timely) access to the benefits of clinical research. In this paper, we will explore the legal regulation and ethical guidance that currently governs pediatric clinical research in the European Union and discuss the future challenges in this field. In addition, we will discuss major ethical concerns in pediatric clinical research, with a focus on the acceptability of research risks and the informed consent process. In the discussion, we will address key concerns in both regulating pediatric clinical research and implementing ethical and legal requirement in the actual pediatric research conduct.

  12. Thermal transport in binary colloidal glasses: Composition dependence and percolation assessment

    NASA Astrophysics Data System (ADS)

    Ruckdeschel, Pia; Philipp, Alexandra; Kopera, Bernd A. F.; Bitterlich, Flora; Dulle, Martin; Pech-May, Nelson W.; Retsch, Markus

    2018-02-01

    The combination of various types of materials is often used to create superior composites that outperform the pure phase components. For any rational design, the thermal conductivity of the composite as a function of the volume fraction of the filler component needs to be known. When approaching the nanoscale, the homogeneous mixture of various components poses an additional challenge. Here, we investigate binary nanocomposite materials based on polymer latex beads and hollow silica nanoparticles. These form randomly mixed colloidal glasses on a sub-μ m scale. We focus on the heat transport properties through such binary assembly structures. The thermal conductivity can be well described by the effective medium theory. However, film formation of the soft polymer component leads to phase segregation and a mismatch between existing mixing models. We confirm our experimental data by finite element modeling. This additionally allowed us to assess the onset of thermal transport percolation in such random particulate structures. Our study contributes to a better understanding of thermal transport through heterostructured particulate assemblies.

  13. Interoperability in healthcare: major challenges in the creation of the enterprise environment

    NASA Astrophysics Data System (ADS)

    Lindsköld, L.; Wintell, M.; Lundberg, N.

    2009-02-01

    There is today a lack of interoperability in healthcare although the need for it is obvious. A new healthcare enterprise environment has been deployed for secure healthcare interoperability in the Western Region in Sweden (WRS). This paper is an empirical overview of the new enterprise environment supporting regional shared and transparent radiology domain information in the WRS. The enterprise environment compromises 17 radiology departments, 1,5 million inhabitants, using different RIS and PACS in a joint work-oriented network and additional cardiology, dentistry and clinical physiology departments. More than 160 terabytes of information are stored in the enterprise repository. Interoperability is developed according to the IHE mission, i.e. applying standards such as Digital Imaging and Communication in Medicine (DICOM) and Health Level 7 (HL7) to address specific clinical communication needs and support optimal patient care. The entire enterprise environment is implemented and used daily in WRS. The central prerequisites in the development of the enterprise environment in western region of Sweden were: 1) information harmonization, 2) reuse of standardized messages e.g. HL7 v2.x and v3.x, 3) development of a holistic information domain including both text and images, and 4) to create a continuous and dynamic update functionality. The central challenges in this project were: 1) the many different vendors acting in the region and the negotiations with them to apply communication roles/profiles such as HL7 (CDA, CCR), DICOM, and XML, 2) the question of whom owns the data, and 3) incomplete technical standards. This study concludes that to create a workflow that runs within an enterprise environment there are a number of central prerequisites and challenges that needs to be in place. This calls for negotiations on an international, national and regional level with standardization organizations, vendors, health management and health personnel.

  14. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kazyak, Eric; Chen, Kuan-Hung; Wood, Kevin N.

    Lithium solid electrolytes are a promising platform for achieving high energy density, long-lasting, and safe rechargeable batteries, which could have widespread societal impact. In particular, the ceramic oxide garnet Li7La3Zr2O12 (LLZO) has been shown to be a promising electrolyte due to its stability and high ionic conductivity. Two major challenges for commercialization are manufacturing of thin layers and creating stable, low-impedance, interfaces with both anode and cathode materials. Atomic Layer Deposition (ALD) has recently been shown as a potential method for depositing both solid electrolytes and interfacial layers to improve the stability and performance at electrode-electrolyte interfaces in battery systems.more » Herein we present the first reported ALD process for LLZO, demonstrating the ability to tune composition within the amorphous film and anneal to achieve the desired cubic garnet phase. Formation of the cubic phase was observed at temperatures as low as 555°C, significantly lower than is required for bulk processing. Additionally, challenges associated with achieving a dense garnet phase due to substrate reactivity, morphology changes and Li loss under the necessary high temperature annealing are quantified via in situ synchrotron diffraction.« less

  15. Appdaptivity: An Internet of Things Device-Decoupled System for Portable Applications in Changing Contexts

    PubMed Central

    Díaz, Manuel; Rubio, Bartolomé; Van den Abeele, Floris

    2018-01-01

    Currently, applications in the Internet of Things (IoT) are tightly coupled to the underlying physical devices. As a consequence, upon adding a device, device replacement or user’s relocation to a different physical space, application developers have to re-perform installation and configuration processes to reconfigure applications, which bears costs in time and knowledge of low-level details. In the emerging IoT field, this issue is even more challenging due to its current unpredictable growth in term of applications and connected devices. In addition, IoT applications can be personalised to each end user and can be present in different environments. As a result, IoT scenarios are very changeable, presenting a challenge for IoT applications. In this paper we present Appdaptivity, a system that enables the development of portable device-decoupled applications that can be adapted to changing contexts. Through Appdaptivity, application developers can intuitively create portable and personalised applications, disengaging from the underlying physical infrastructure. Results confirms a good scalability of the system in terms of connected users and components involved. PMID:29701698

  16. An alternative animal protein source: cultured beef.

    PubMed

    Post, Mark J

    2014-11-01

    Alternative sources of animal proteins are needed that can be produced efficiently, thereby providing food security with diminished ecological burden. It is feasible to culture beef from bovine skeletal muscle stem cells, but the technology is still under development. The aim is to create a beef mimic with equivalent taste, texture, and appearance and with the same nutritional value as livestock-produced beef. More specifically, there is a need for optimization of protein content and fat content. In addition, scalability of production requires modification of current small-scale bioreactors to the largest possible scale. The necessary steps and current progress suggest that this aim is achievable, but formal evidence is still required. Similarly, we can be optimistic about consumer acceptance based on initial data, but detailed studies are needed to gain more insight into potential psychological obstacles that could lead to rejection. These challenges are formidable but likely surmountable. The severity of upcoming food-security threats warrants serious research and development efforts to address the challenges that come with bringing cultured beef to the market. © 2014 New York Academy of Sciences.

  17. Veterinary professional associates: does the profession's foresight include a mid-tier professional similar to physician assistants?

    PubMed

    Kogan, Lori R; Stewart, Sherry M

    2009-01-01

    The projected shortage of veterinarians has created a need to explore alternatives designed to meet society's future demands. A veterinary professional health care provider, similar to the human medical profession's physician assistant (PA), is one such alternative. To explore this option, this paper provides background information on the development of PAs, including the motivations behind the initiative and the history of the role's development. Rather than aiming for a persuasive appeal, the authors have written this article with the intent of fostering discussion. It is suggested that perhaps veterinary professional associates, modeled after PAs, could be employed to handle routine veterinary care and thereby allow veterinarians additional time to focus on the more demanding and challenging aspects of veterinary medicine. Perhaps a team approach, similar to the physician/PA team, could help the field of veterinary medicine to better serve both clients and patients. As veterinary medicine directs its attention toward the new challenges on the horizon, creative solutions will be needed. Perhaps some variation of a veterinary professional associate is worthy of future discussion.

  18. Recent developments in turbomachinery component materials and manufacturing challenges for aero engine applications

    NASA Astrophysics Data System (ADS)

    Srinivas, G.; Raghunandana, K.; Satish Shenoy, B.

    2018-02-01

    In the recent years the development of turbomachinery materials performance enhancement plays a vital role especially in aircraft air breathing engines like turbojet engine, turboprop engine, turboshaft engine and turbofan engines. Especially the transonic flow engines required highly sophisticated materials where it can sustain the entire thrust which can create by the engine. The main objective of this paper is to give an overview of the present cost-effective and technological capabilities process for turbomachinery component materials. Especially the main focus is given to study the Electro physical, Photonic additive removal process and Electro chemical process for turbomachinery parts manufacture. The aeronautical propulsion based technologies are reviewed thoroughly where in surface reliability, geometrical precession, and material removal and highly strengthened composite material deposition rates usually difficult to cut dedicated steels, Titanium and Nickel based alloys. In this paper the past aeronautical and propulsion mechanical based manufacturing technologies, current sophisticated technologies and also future challenging material processing techniques are covered. The paper also focuses on the brief description of turbomachinery components of shaping process and coating in aeromechanical applications.

  19. Big data management challenges in health research-a literature review.

    PubMed

    Wang, Xiaoming; Williams, Carolyn; Liu, Zhen Hua; Croghan, Joe

    2017-08-07

    Big data management for information centralization (i.e. making data of interest findable) and integration (i.e. making related data connectable) in health research is a defining challenge in biomedical informatics. While essential to create a foundation for knowledge discovery, optimized solutions to deliver high-quality and easy-to-use information resources are not thoroughly explored. In this review, we identify the gaps between current data management approaches and the need for new capacity to manage big data generated in advanced health research. Focusing on these unmet needs and well-recognized problems, we introduce state-of-the-art concepts, approaches and technologies for data management from computing academia and industry to explore improvement solutions. We explain the potential and significance of these advances for biomedical informatics. In addition, we discuss specific issues that have a great impact on technical solutions for developing the next generation of digital products (tools and data) to facilitate the raw-data-to-knowledge process in health research. Published by Oxford University Press 2017. This work is written by US Government employees and is in the public domain in the US.

  20. Appdaptivity: An Internet of Things Device-Decoupled System for Portable Applications in Changing Contexts.

    PubMed

    Martín, Cristian; Hoebeke, Jeroen; Rossey, Jen; Díaz, Manuel; Rubio, Bartolomé; Van den Abeele, Floris

    2018-04-26

    Currently, applications in the Internet of Things (IoT) are tightly coupled to the underlying physical devices. As a consequence, upon adding a device, device replacement or user’s relocation to a different physical space, application developers have to re-perform installation and configuration processes to reconfigure applications, which bears costs in time and knowledge of low-level details. In the emerging IoT field, this issue is even more challenging due to its current unpredictable growth in term of applications and connected devices. In addition, IoT applications can be personalised to each end user and can be present in different environments. As a result, IoT scenarios are very changeable, presenting a challenge for IoT applications. In this paper we present Appdaptivity, a system that enables the development of portable device-decoupled applications that can be adapted to changing contexts. Through Appdaptivity, application developers can intuitively create portable and personalised applications, disengaging from the underlying physical infrastructure. Results confirms a good scalability of the system in terms of connected users and components involved.

  1. pTcGW plasmid vectors 1.1 version: a versatile tool for Trypanosoma cruzi gene characterisation

    PubMed Central

    Kugeratski, Fernanda G; Batista, Michel; Inoue, Alexandre Haruo; Ramos, Bruno Dias; Krieger, Marco Aurelio; Marchini/, Fabricio K

    2015-01-01

    The functional characterisation of thousands of Trypanosoma cruzi genes remains a challenge. Reverse genetics approaches compatible with high-throughput cloning strategies can provide the tool needed to tackle this challenge. We previously published the pTcGW platform, composed by plasmid vectors carrying different options of N-terminal fusion tags based on Gateway® technology. Here, we present an improved 1.1 version of pTcGW vectors, which is characterised by a fully flexible structure allowing an easy customisation of each element of the vectors in a single cloning step. Additionally, both N and C-terminal fusions are available with new tag options for protein complexes purification. Three of the newly created vectors were successfully used to determine the cellular localisation of four T. cruzi proteins. The 1.1 version of pTcGW platform can be used in a variety of assays, such as protein overexpression, identification of protein-protein interaction and protein localisation. This powerful and versatile tool allows adding valuable functional information to T. cruzi genes and is freely available for scientific community. PMID:26200713

  2. Dense blocks of energetic ions driven by multi-petawatt lasers

    PubMed Central

    Weng, S. M.; Liu, M.; Sheng, Z. M.; Murakami, M.; Chen, M.; Yu, L. L.; Zhang, J.

    2016-01-01

    Laser-driven ion accelerators have the advantages of compact size, high density, and short bunch duration over conventional accelerators. Nevertheless, it is still challenging to simultaneously enhance the yield and quality of laser-driven ion beams for practical applications. Here we propose a scheme to address this challenge via the use of emerging multi-petawatt lasers and a density-modulated target. The density-modulated target permits its ions to be uniformly accelerated as a dense block by laser radiation pressure. In addition, the beam quality of the accelerated ions is remarkably improved by embedding the target in a thick enough substrate, which suppresses hot electron refluxing and thus alleviates plasma heating. Particle-in-cell simulations demonstrate that almost all ions in a solid-density plasma of a few microns can be uniformly accelerated to about 25% of the speed of light by a laser pulse at an intensity around 1022 W/cm2. The resulting dense block of energetic ions may drive fusion ignition and more generally create matter with unprecedented high energy density. PMID:26924793

  3. Context, Challenges, and Tensions in Global Efforts to Engage Men in the Prevention of Violence against Women: An Ecological Analysis

    PubMed Central

    Casey, Erin A.; Carlson, Juliana; Fraguela-Rios, Cathlyn; Kimball, Ericka; Neugut, Tova B.; Tolman, Richard M.; Edleson, Jeffrey L.

    2014-01-01

    As gender-based violence prevention programs around the world increasingly include efforts to engage men and boys as antiviolence allies, both the profound benefits and the inherent complexities of these efforts are emerging. Acknowledging and exploring tensions associated with engaging men is an important element of thoughtfully fostering men’s antiviolence ally movements so as to both respectfully invite men into anti-violence work and create effective, gender-equitable prevention programming. To this end, this study presents descriptive findings regarding challenges associated with men’s engagement programming from in-depth interviews with twenty-nine representatives of organizations that engage men and boys in preventing violence against women and girls in Africa, Asia, Europe, Oceania, and North and South America. Programs reported negotiating complex issues related to gender, the intersectional nature of men’s identities, and establishing legitimacy and sustainability within communities while maintaining ideological focus and consistency. Additionally, programs reported that these tensions manifest across ecological layers of analysis, and impact both the participation of individual men and the programs’ experiences in community and national contexts. PMID:25568612

  4. Design and Lessons Learned on the Development of a Cryogenic Pupil Select Mechanism used in the Testing and Calibration of the Integrated Science Instrument Module (ISIM) on the James Webb Space Telescope (JWST)

    NASA Technical Reports Server (NTRS)

    Mitchell, Alissa; Capon, Thomas; Guzek, Jeffrey; Hakun, Claef; Haney, Paul; Koca, Corina

    2014-01-01

    Calibration and testing of the instruments on the Integrated Science Instrument Module (ISIM) of the James Webb Space Telescope (JWST) is being performed by the use of a cryogenic, full-field, optical simulator that was constructed for this purpose. The Pupil Select Mechanism (PSM) assembly is one of several mechanisms and optical elements that compose the Optical Telescope Element SIMulator, or OSIM. The PSM allows for several optical elements to be inserted into the optical plane of OSIM, introducing a variety of aberrations, distortions, obscurations, and other calibration states into the pupil plane. The following discussion focuses on the details of the design evolution, analysis, build, and test of this mechanism along with the challenges associated with creating a sub arc-minute positioning mechanism operating in an extreme cryogenic environment. In addition, difficult challenges in the control system design will be discussed including the incorporation of closed-loop feedback control into a system that was designed to operate in an open-loop fashion.

  5. Design and Lessons Learned on the Development of a Cryogenic Pupil Select Mechanism Used in the Testing and Calibration of the Integrated Science Instrument Module (ISIM) on the James Webb Space Telescope (JWST)

    NASA Technical Reports Server (NTRS)

    Mitchell, Alissa; Capon, Thomas; Guzek, Jeffrey; Hakun, Claef; Haney, Paul; Koca, Corina

    2014-01-01

    Calibration and testing of the instruments on the Integrated Science Instrument Module (ISIM) of the James Webb Space Telescope (JWST) is being performed by the use of a cryogenic, full-field, optical simulator that was constructed for this purpose. The Pupil Select Mechanism (PSM) assembly is one of several mechanisms and optical elements that compose the Optical Telescope Element SIMulator, or OSIM. The PSM allows for several optical elements to be inserted into the optical plane of OSIM, introducing a variety of aberrations, distortions, obscurations, and other calibration states into the pupil plane. The following discussion focuses on the details of the design evolution, analysis, build, and test of this mechanism along with the challenges associated with creating a sub arc-minute positioning mechanism operating in an extreme cryogenic environment. In addition, difficult challenges in the control system design will be discussed including the incorporation of closed-loop feedback control into a system that was designed to operate in an open-loop fashion.

  6. Care plan program reduces the number of visits for challenging psychiatric patients in the ED.

    PubMed

    Abello, Arthur; Brieger, Ben; Dear, Kim; King, Ben; Ziebell, Chris; Ahmed, Atheer; Milling, Truman J

    2012-09-01

    A small number of patients representing a significant demand on emergency department (ED) services present regularly for a variety of reasons, including psychiatric or behavioral complaints and lack of access to other services. A care plan program was created as a database of ED high users and patients of concern, as identified by ED staff and approved by program administrators to improve care and mitigate ED strain. A list of medical record numbers was assembled by searching the care plan program database for adult patients initially enrolled between the dates of November 1, 2006, and October 21, 2007. Inclusion criteria were the occurrence of a psychiatric International Classification Diseases, Ninth Revision, code in their medical record and a care plan level implying a serious psychiatric disorder causing harmful behavior. Additional data about these patients were acquired using an indigent care tracking database and electronic medical records. Variables collected from these sources were analyzed for changes before and after program enrollment. Of 501 patients in the database in the period studied, 48 patients fulfilled the criteria for the cohort. There was a significant reduction in the number of visits to the ED from the year before program enrollment to the year after enrollment (8.9, before; 5.9, after; P < .05). There was also an increase in psychiatric hospital visits (2%, before; 25%, after; P < .05). An alert program that identifies challenging ED patients with psychiatric conditions and creates a care plan appears to reduce visits and lead to more appropriate use of other resources. Copyright © 2012 Elsevier Inc. All rights reserved.

  7. Estimating Precipitation Input to a Watershed by Combining Gauge and Radar Derived Observations

    NASA Astrophysics Data System (ADS)

    Ercan, M. B.; Goodall, J. L.

    2011-12-01

    One challenge in creating an accurate watershed model is obtaining estimates of precipitation intensity over the watershed area. While precipitation measurements are generally available from gauging stations and radar instruments, both of these approaches for measuring precipitation have strengths and weakness. A typical way of addressing this challenge is to use gauged precipitation estimates to calibrate radar based estimates, however this study proposes a slightly different approach in which the optimal daily precipitation value is selected from either the gauged or the radar estimates based on the observed streamflow for that day. Our proposed approach is perhaps most relevant for cases of modeling watersheds that do not have a nearby precipitation gauge, or for regions that experience convective storms that are often highly spatially variable. Using the Eno River watershed located in Orange County, NC, three different precipitation datasets were created to predict streamflow at the watershed outlet for the time period 2005-2010 using the Soil and Water Assessment Tool (SWAT): (1) estimates based on only precipitation gauging stations, (2) estimates based only on gauged-corrected radar observations, and (3) the combination of precipitation estimates from the gauge and radar data determined using our proposed approach. The results show that the combined precipitation approach significantly improves streamflow predictions (Nash-Sutcliffe Coefficient, E = 0.66) when compared to the gauged estimates alone (E = 0.47) and the radar based estimates alone (E = 0.45). Our study was limited to one watershed, therefore additional studies are needed to control for factors such as climate, ecology, and hydrogeology that will likely influence the results of the analysis.

  8. A Method to Represent Heterogeneous Materials for Rapid Prototyping: The Matryoshka Approach

    PubMed Central

    Lei, Shuangyan; Frank, Matthew C.; Anderson, Donald D.; Brown, Thomas D.

    2015-01-01

    Purpose The purpose of this paper is to present a new method for representing heterogeneous materials using nested STL shells, based, in particular, on the density distributions of human bones. Design/methodology/approach Nested STL shells, called Matryoshka models, are described, based on their namesake Russian nesting dolls. In this approach, polygonal models, such as STL shells, are “stacked” inside one another to represent different material regions. The Matryoshka model addresses the challenge of representing different densities and different types of bone when reverse engineering from medical images. The Matryoshka model is generated via an iterative process of thresholding the Hounsfield Unit (HU) data using computed tomography (CT), thereby delineating regions of progressively increasing bone density. These nested shells can represent regions starting with the medullary (bone marrow) canal, up through and including the outer surface of the bone. Findings The Matryoshka approach introduced can be used to generate accurate models of heterogeneous materials in an automated fashion, avoiding the challenge of hand-creating an assembly model for input to multi-material additive or subtractive manufacturing. Originality/Value This paper presents a new method for describing heterogeneous materials: in this case, the density distribution in a human bone. The authors show how the Matryoshka model can be used to plan harvesting locations for creating custom rapid allograft bone implants from donor bone. An implementation of a proposed harvesting method is demonstrated, followed by a case study using subtractive rapid prototyping to harvest a bone implant from a human tibia surrogate. PMID:26120277

  9. Validating Domains of Patient Contextual Factors Essential to Preventing Contextual Errors: A Qualitative Study Conducted at Chicago Area Veterans Health Administration Sites.

    PubMed

    Binns-Calvey, Amy E; Malhiot, Alex; Kostovich, Carol T; LaVela, Sherri L; Stroupe, Kevin; Gerber, Ben S; Burkhart, Lisa; Weiner, Saul J; Weaver, Frances M

    2017-09-01

    "Patient context" indicates patient circumstances and characteristics or states that are essential to address when planning patient care. Specific patient "contextual factors," if overlooked, result in an inappropriate plan of care, a medical error termed a "contextual error." The myriad contextual factors that constitute patient context have been grouped into broad domains to create a taxonomy of challenges to consider when planning care. This study sought to validate a previously identified list of contextual domains. This qualitative study used directed content analysis. In 2014, 19 Department of Veterans Affairs (VA) providers (84% female) and 49 patients (86% male) from two VA medical centers and four outpatient clinics in the Chicago area participated in semistructured interviews and focus groups. Topics included patient-specific, community, and resource-related factors that affect patients' abilities to manage their care. Transcripts were analyzed with a previously identified list of contextual domains as a framework. Analysis of responses revealed that patients and providers identified the same 10 domains previously published, plus 3 additional ones. Based on comments made by patients and providers, the authors created a revised list of 12 domains from themes that emerged. Six pertain to patient circumstances such as access to care and financial situation, and 6 to patient characteristics/states including skills, abilities, and knowledge. Contextual factors in patients' lives may be essential to address for effective care planning. The rubric developed can serve as a "contextual differential" for clinicians to consider when addressing challenges patients face when planning their care.

  10. Pectoral muscle segmentation in breast tomosynthesis with deep learning

    NASA Astrophysics Data System (ADS)

    Rodriguez-Ruiz, Alejandro; Teuwen, Jonas; Chung, Kaman; Karssemeijer, Nico; Chevalier, Margarita; Gubern-Merida, Albert; Sechopoulos, Ioannis

    2018-02-01

    Digital breast tomosynthesis (DBT) has superior detection performance than mammography (DM) for population-based breast cancer screening, but the higher number of images that must be reviewed poses a challenge for its implementation. This may be ameliorated by creating a twodimensional synthetic mammographic image (SM) from the DBT volume, containing the most relevant information. When creating a SM, it is of utmost importance to have an accurate lesion localization detection algorithm, while segmenting fibroglandular tissue could also be beneficial. These tasks encounter an extra challenge when working with images in the medio-lateral oblique view, due to the presence of the pectoral muscle, which has similar radiographic density. In this work, we present an automatic pectoral muscle segmentation model based on a u-net deep learning architecture, trained with 136 DBT images acquired with a single system (different BIRADS ® densities and pathological findings). The model was tested on 36 DBT images from that same system resulting in a dice similarity coefficient (DSC) of 0.977 (0.967-0.984). In addition, the model was tested on 125 images from two different systems and three different modalities (DBT, SM, DM), obtaining DSCs between 0.947 and 0.970, a range determined visually to provide adequate segmentations. For reference, a resident radiologist independently annotated a mix of 25 cases obtaining a DSC of 0.971. The results suggest the possibility of using this model for inter-manufacturer DBT, DM and SM tasks that benefit from the segmentation of the pectoral muscle, such as SM generation, computer aided detection systems, or patient dosimetry algorithms.

  11. The Benefits of a Real-Time Web-Based Response System for Enhancing Engaged Learning in Classrooms and Public Science Events.

    PubMed

    Sarvary, Mark A; Gifford, Kathleen M

    2017-01-01

    Large introduction to neuroscience classes and small science cafés have the same goal: bridging the gap between the presenter and the audience to convey the information while being engaging. Early classroom response systems became the cornerstone of flipped and engaged learning. These "clickers" helped turn lectures into dialogues, allowing the presenter to become a facilitator rather than a "sage on the stage." Rapid technological developments, especially the increase of computing power opened up new opportunities, moving these systems from a clicker device onto cellphones and laptops. This allowed students to use their own devices, and instructors to use new question types, such as clicking on a picture or ranking concepts. A variety of question types makes the learning environment more engaging, allows better examples for creative and critical thinking, and facilitates assessment. Online access makes these response systems scalable, bringing the strength of formative assessments and surveys to public science communication events, neuroscience journal clubs and distance learning. In addition to the new opportunities, online polling systems also create new challenges for the presenters. For example, allowing mobile devices in the classroom can be distracting. Here, a web-based, real-time response system called Poll Everywhere was compared to iClickers, highlighting the benefits and the pitfalls of both systems. In conclusion, the authors observe that the benefits of web-based response systems outweigh the challenges, and this form of digital pedagogy can help create a rich dialogue with the audience in large classrooms as well as in public science events.

  12. Creating Meaningful Change in Education: A Cascading Logic Model. Scaling-Up Brief. Number 6

    ERIC Educational Resources Information Center

    Blase, Karen; Fixsen, Dean; Jackson, Kathleen Ryan

    2015-01-01

    Creating meaningful change in a state's education system from the capitol to the classroom is complex and challenging work. Over the past several decades, considerable research, policy, and funding have focused on the use of evidence-based programs (EBP) in schools. However, these practices only are effective when fully and effectively implemented…

  13. Video Game Development Strategies for Creating Successful Cognitively Challenging Games

    ERIC Educational Resources Information Center

    Williams, Walter K.

    2018-01-01

    The video game industry is a global multibillion dollar industry with millions of players. The process of developing video games is essential for the continued growth of the industry, and developers need to employ effective strategies that will help them to create successful games. The purpose of this explorative qualitative single case study was…

  14. Construction-Paper Puzzle Masterpieces

    ERIC Educational Resources Information Center

    Vance, Shelly

    2010-01-01

    Creating an appreciation of art history in her junior-high students has always been one of the author's greatest challenges as an art teacher. In this article, the author describes how her eighth-grade students re-created a famous work of art--piece by piece, like a puzzle or a stained-glass window--out of construction paper. (Contains 1 resource.)

  15. Creating a Positive Social-Emotional Climate in Your Elementary Physical Education Program

    ERIC Educational Resources Information Center

    Gagnon, Amy G.

    2016-01-01

    Creating a positive social-emotional climate must be the backbone of a quality elementary physical education program. The need to belong, have friends, and feel emotionally safe are basic needs everyone has, but meeting these needs in the classroom can be challenging at times. Strategies regarding how to implement a positive social-emotional…

  16. Attacking Poverty. World Development Report, 2000/2001.

    ERIC Educational Resources Information Center

    World Bank, Washington, DC.

    This report seeks to expand the understanding of poverty and its causes and sets out actions to create to create a world free of poverty in all its dimensions. The report both builds on past thinking and strategy and substantially broadens and deepens what is judged to be necessary to meet the challenge of reducing poverty. It argues that major…

  17. Impact of Metacognitive Practices and Assorted Assessment Modalities towards Creating Self-Regulated Learners

    ERIC Educational Resources Information Center

    Nair N., Sreevrinda

    2014-01-01

    Worldwide efforts are increasing to infuse thinking skills into the curriculum, which are part of cognitive behavior, and to include them in the instructional strategies, which will make the learner producer of knowledge and help to create a sense of responsibility among them. Metacognitive learning activities immerse students in challenging tasks…

  18. Addressing the Needs of Overweight Students in Elementary Physical Education: Creating an Environment of Care and Success

    ERIC Educational Resources Information Center

    Tingstrom, Catherine A.

    2015-01-01

    The rising prevalence of obesity in society has resulted in an increased need for physical education teachers to create learning opportunities that promote physical activity among children. However, the presence of anti-fat attitudes and a limited understanding of the challenges associated with being overweight in a physical activity environment…

  19. Inspiration and Intellect: Significant Learning in Musical Forms and Analysis

    ERIC Educational Resources Information Center

    Kelley, Bruce C.

    2009-01-01

    In his book "Creating Significant Learning Experiences" (2003), Dee Fink challenges professors to create a deep vision for the courses they teach. Educators often have a vision for what their courses could be, but often lack a model for instituting change. Fink's book provides that model. In this article, the author describes how this model helped…

  20. 77 FR 48157 - Office of the National Coordinator for Health Information Technology; Announcement of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-13

    ... on YouTube.com or Vimeo.com (the Video should be no longer than 2 minutes); A text description of... open call for the public to create short, inspiring videos sharing how you use technology to manage... Challenge invites you to create short, inspiring videos sharing how you use technology to manage your...

  1. Satellite Maps Deliver More Realistic Gaming

    NASA Technical Reports Server (NTRS)

    2013-01-01

    When Redwood City, California-based Electronic Arts (EA) decided to make SSX, its latest snowboarding video game, it faced challenges in creating realistic-looking mountains. The solution was NASA's ASTER Global Digital Elevation Map, made available by the Jet Propulsion Laboratory, which EA used to create 28 real-life mountains from 9 different ranges for its award-winning game.

  2. 2012 Presidential Address: Daring to Be Different Using Five Discovery Skills

    ERIC Educational Resources Information Center

    Buck, Sue

    2012-01-01

    In "The Innovator's DNA, Mastering the Five Skills of Disruptive Innovators," authors Jeff Dyer, Hal Gregersen, and Clayton M. Christensen, challenge the reader to become more innovative and impactful. They share three levels of innovation. Level one is creating enough program change so it creates interest for people to come back. Level two is…

  3. A Qualitative Study Using Project-Based Learning in a Mainstream Middle School

    ERIC Educational Resources Information Center

    Wurdinger, Scott; Haar, Jean; Hugg, Robert; Bezon, Jennifer

    2007-01-01

    Project-based learning taps into students' interests by allowing them to create projects that result in meaningful learning experiences. The method requires teachers to identify projects that challenge students to work individually or in groups to create plans, solve problems they encounter, test their ideas, and present their projects to peers.…

  4. Business as Usual? It's Just Not an Option

    ERIC Educational Resources Information Center

    Blewitt, John

    2010-01-01

    There is no doubt that in order to address the serious challenges arising from anthropogenic--or human-produced--climate change, Britain, along with the rest of the world, needs to adopt policies and develop skills that will create a low-carbon economy with a highly effective use of renewable and natural resources. People need to create the…

  5. Overview of the Future Forest Webinar Series [Chapter 1

    Treesearch

    Sarah Hines; Megan Matonis

    2014-01-01

    The Future Forest Webinar Series was created to facilitate dialogue between scientists and managers about the challenges and opportunities created by the mountain pine beetle1 (MPB) epidemic. A core team of scientists and managers from the USFS Rocky Mountain Research Station and the Northern and Rocky Mountain Regions worked together to develop the format and content...

  6. Multicultural Education: A Challenge for All.

    ERIC Educational Resources Information Center

    Fallahi, Mitra

    This paper addresses the role of the classroom in bringing students of different backgrounds together and the role of the teacher in creating an atmosphere in which students not only get along well with each other, but also develop respect and appreciation that they carry with them outside of school. There is a need to create an atmosphere of…

  7. Health Information Technology Challenges to Support Patient-Centered Care Coordination

    PubMed Central

    Séroussi, B.; Jaulent, M.-C.; Lehmann, C. U.

    2015-01-01

    Summary Objectives To provide an editorial introduction to the 2015 IMIA Yearbook of Medical Informatics. Methods We provide a brief overview of the 2015 special topic “Patient-Centered Care Coordination”, discuss the addition of two new sections to the Yearbook, Natural Language Processing and Public Health & Epidemiology Informatics, and present our editorial plans for the upcoming celebration of the 25th anniversary of the Yearbook. Results Care delivery currently occurs through the processing of complex clinical pathways designed for increasingly multi-morbid patients by various practitioners in different settings. To avoid the consequences of the fragmentation of services, care should be organized to coordinate all providers, giving them the opportunity to share the same holistic view of the patient’s condition, and to be informed of the planned clinical pathway that establishes the roles and interventions of each one. The adoption and use of electronic health records (EHRs) is a solution to address health information sharing and care coordination challenges. However, while EHRs are necessary, they are not sufficient to achieve care coordination, creating information availability does not mean the information will be accessed. This edition of the Yearbook acknowledges the fact that health information technology (HIT), and EHRs in particular, are not yet fully addressing the challenges in care coordination. Emerging trends, tools, and applications of HIT to support care coordination are presented through the keynote paper, survey papers, and working group contributions. Conclusions In 2015, the IMIA Yearbook has been extended to emphasize two fields of biomedical informatics through new sections. Next year, the 25th anniversary of the Yearbook will be celebrated in grand style! A special issue with a touch of reflection, a bit of rediscovery, and some “science-fiction” will be published in addition to the usual edition. PMID:26123912

  8. JPSS Preparations at the Satellite Proving Ground for Marine, Precipitation, and Satellite Analysis

    NASA Astrophysics Data System (ADS)

    Folmer, M. J.; Berndt, E.; Clark, J.; Orrison, A.; Kibler, J.; Sienkiewicz, J. M.; Nelson, J. A., Jr.; Goldberg, M.

    2016-12-01

    The National Oceanic and Atmospheric Administration (NOAA) Satellite Proving Ground (PG) for Marine, Precipitation, and Satellite Analysis (MPS) has been demonstrating and evaluating Suomi National Polar-orbiting Partnership (S-NPP) products along with other polar-orbiting satellite platforms in preparation for the Joint Polar Satellite System - 1 (JPSS-1) launch in March 2017. The first S-NPP imagery was made available to the MPS PG during the evolution of Hurricane Sandy in October 2012 and has since been popular in operations. Since this event the MPS PG Satellite Liaison has been working with forecasters on ways to integrate single-channel and multispectral imagery from the Visible Infrared Imaging Radiometer Suite (VIIRS), the Moderate Resolution Imaging Spectroradiometer (MODIS), and the Advanced Very High Resolution Radiometer (AVHRR)into operations to complement numerical weather prediction and geostationary satellite savvy National Weather Service (NWS) National Centers. Additional unique products have been introduced to operations to address specific forecast challenges, including the Cooperative Institute for Research in the Atmosphere (CIRA) Layered Precipitable Water, the National Environmental Satellite, Data, and Information Service (NESDIS) Snowfall Rate product, NOAA Unique Combined Atmospheric Processing System (NUCAPS) Soundings, ozone products from the Atmospheric Infrared Sounder (AIRS), Cross-track Infrared Sounder/Advanced Technology Microwave Sounder (CrIS/ATMS), and Infrared Atmospheric Sounding Interferometer (IASI). In addition, new satellite domains have been created to provide forecasters at the NWS Ocean Prediction Center and Weather Prediction Center with better quality imagery at high latitudes. This has led to research projects that are addressing forecast challenges such as tropical to extratropical transition and explosive cyclogenesis. This presentation will provide examples of how the MPS PG has been introducing and integrating these products into operations to help solve these forecast challenges.

  9. Health Information Technology Challenges to Support Patient-Centered Care Coordination.

    PubMed

    Séroussi, B; Jaulent, M-C; Lehmann, C U

    2015-08-13

    To provide an editorial introduction to the 2015 IMIA Yearbook of Medical Informatics. We provide a brief overview of the 2015 special topic "Patient-Centered Care Coordination", discuss the addition of two new sections to the Yearbook, Natural Language Processing and Public Health & Epidemiology Informatics, and present our editorial plans for the upcoming celebration of the 25th anniversary of the Yearbook. Care delivery currently occurs through the processing of complex clinical pathways designed for increasingly multi-morbid patients by various practitioners in different settings. To avoid the consequences of the fragmentation of services, care should be organized to coordinate all providers, giving them the opportunity to share the same holistic view of the patient's condition, and to be informed of the planned clinical pathway that establishes the roles and interventions of each one. The adoption and use of electronic health records (EHRs) is a solution to address health information sharing and care coordination challenges. However, while EHRs are necessary, they are not sufficient to achieve care coordination, creating information availability does not mean the information will be accessed. This edition of the Yearbook acknowledges the fact that health information technology (HIT), and EHRs in particular, are not yet fully addressing the challenges in care coordination. Emerging trends, tools, and applications of HIT to support care coordination are presented through the keynote paper, survey papers, and working group contributions. In 2015, the IMIA Yearbook has been extended to emphasize two fields of biomedical informatics through new sections. Next year, the 25th anniversary of the Yearbook will be celebrated in grand style! A special issue with a touch of reflection, a bit of rediscovery, and some "science-fiction" will be published in addition to the usual edition.

  10. In-Space Recycler Technology Demonstration

    NASA Technical Reports Server (NTRS)

    Hoyt, Rob; Werkheiser, NIKI; Kim, Tony

    2016-01-01

    In 2014, a 3D printer was installed and used successfully on the International Space Station (ISS), creating the first additively manufactured part in space. While additive manufacturing is a game changing technology for exploration missions, the process still requires raw feedstock material to fabricate parts. Without a recycling capability, a large supply of feedstock would need to be stored onboard, which negates the logistical benefits of these capabilities. Tethers Unlimited, Inc. (TUI), received a Small Business Innovation Research (SBIR) award to design and build the first In-space Recycler for demonstration aboard the ISS in 2017. To fully test this technology in microgravity, parts will be 3D printed, recycled into reusable filament, and then reprinted into new parts. Recycling scrap into printer filament is quite challenging in that a recycler must be able to handle a large variety of possible scrap configurations and densities. New challenges include: dealing with inevitable contamination of the scrap material, minimizing damage to the molecular structure of the plastic during reprocessing, managing a larger volume of hot liquid plastic, and exercising greater control over the cooling/resolidification of the material. TUI has developed an architecture that addresses these challenges by combining standard, proven technologies with novel, patented processes developed through this effort. Results show that the filament diameter achieved is more consistent than commercial filament, with only minimal degradation of material properties over recycling steps. In May 2016, TUI completed fabrication of a flight prototype, which will ultimately progress to the demonstration unit for the ISS as a testbed for future exploration missions. This capability will provide significant cost savings by reducing the launch mass and volume required for printer feedstock as well as reduce waste that must be stored or disposed.

  11. Time for a change: addressing R&D and commercialization challenges for antibacterials.

    PubMed

    Payne, David J; Miller, Linda Federici; Findlay, David; Anderson, James; Marks, Lynn

    2015-06-05

    The antibacterial therapeutic area has been described as the perfect storm. Resistance is increasing to the point that our hospitals encounter patients infected with untreatable pathogens, the overall industry pipeline is described as dry and most multinational pharmaceutical companies have withdrawn from the area. Major contributing factors to the declining antibacterial industry pipeline include scientific challenges, clinical/regulatory hurdles and low return on investment. This paper examines these challenges and proposes approaches to address them. There is a need for a broader scientific agenda to explore new approaches to discover and develop antibacterial agents. Additionally, ideas of how industry and academia could be better integrated will be presented. While promising progress in the regulatory environment has been made, more streamlined regulatory paths are still required and the solutions will lie in global harmonization and clearly defined guidance. Creating the right incentives for antibacterial research and development is critical and a new commercial model for antibacterial agents will be proposed. One key solution to help resolve both the problem of antimicrobial resistance (AMR) and lack of new drug development are rapid, cost-effective, accurate point of care diagnostics that will transform antibacterial prescribing and enable more cost-effective and efficient antibacterial clinical trials. The challenges of AMR are too great for any one group to resolve and success will require leadership and partnerships among academia, industry and governments globally. © 2015 The Author(s) Published by the Royal Society. All rights reserved.

  12. Creating an "Education Shark Tank" to Encourage and Support Educational Scholarship and Innovation.

    PubMed

    Cofrancesco, Joseph; Wright, Scott M; Vohr, Eric; Ziegelstein, Roy C

    2017-11-01

    Creating and supporting opportunities for innovation that showcase and reward creativity in medical and biomedical education is critically important for academic institutions, learners, and faculty. In 2014, the Institute for Excellence in Education at Johns Hopkins University School of Medicine created a small grant program called Education Shark Tank, in which two to five finalist teams present their proposals on innovative initiatives to improve education to four or five senior educator "sharks" at an educational conference, with an audience. The sharks then "grill" the presenters, considering which if any to fund, focusing on the rationale, feasibility, appropriateness of the outcome measures, evaluation and assessment plan, and proposed method of dissemination. They also make suggestions that challenge the presenters to assess and improve their designs. In the program's first year (2014), funds were divided equally between two projects, both of which were successfully completed and one of which led to a journal publication; this led to increased funding for the program in 2015. Participants have called Education Shark Tank a "challenging and rewarding experience." Education Shark Tank can facilitate educational innovation and scholarship via engaging and challenging interactions between grant applicants and reviewers in a public venue. The authors plan to conduct a five-year survey (after 2018) of all Education Shark Tank finalists to determine the success and challenges the funded projects have had, what scholarly dissemination has occurred, whether nonfunded projects were able to move forward, and the value of the feedback and mentoring received.

  13. Engineering design: A cognitive process approach

    NASA Astrophysics Data System (ADS)

    Strimel, Greg Joseph

    The intent of this dissertation was to identify the cognitive processes used by advanced pre-engineering students to solve complex engineering design problems. Students in technology and engineering education classrooms are often taught to use an ideal engineering design process that has been generated mostly by educators and curriculum developers. However, the review of literature showed that it is unclear as to how advanced pre-engineering students cognitively navigate solving a complex and multifaceted problem from beginning to end. Additionally, it was unclear how a student thinks and acts throughout their design process and how this affects the viability of their solution. Therefore, Research Objective 1 was to identify the fundamental cognitive processes students use to design, construct, and evaluate operational solutions to engineering design problems. Research Objective 2 was to determine identifiers within student cognitive processes for monitoring aptitude to successfully design, construct, and evaluate technological solutions. Lastly, Research Objective 3 was to create a conceptual technological and engineering problem-solving model integrating student cognitive processes for the improved development of problem-solving abilities. The methodology of this study included multiple forms of data collection. The participants were first given a survey to determine their prior experience with engineering and to provide a description of the subjects being studied. The participants were then presented an engineering design challenge to solve individually. While they completed the challenge, the participants verbalized their thoughts using an established "think aloud" method. These verbalizations were captured along with participant observational recordings using point-of-view camera technology. Additionally, the participant design journals, design artifacts, solution effectiveness data, and teacher evaluations were collected for analysis to help achieve the research objectives of this study. Two independent coders then coded the video/audio recordings and the additional design data using Halfin's (1973) 17 mental processes for technological problem-solving. The results of this study indicated that the participants employed a wide array of mental processes when solving engineering design challenges. However, the findings provide a general analysis of the number of times participants employed each mental process, as well as the amount of time consumed employing the various mental processes through the different stages of the engineering design process. The results indicated many similarities between the students solving the problem, which may highlight voids in current technology and engineering education curricula. Additionally, the findings showed differences between the processes employed by participants that created the most successful solutions and the participants who developed the least effective solutions. Upon comparing and contrasting these processes, recommendations for instructional strategies to enhance a student's capability for solving engineering design problems were developed. The results also indicated that students, when left without teacher intervention, use a simplified and more natural process to solve design challenges than the 12-step engineering design process reported in much of the literature. Lastly, these data indicated that students followed two different approaches to solving the design problem. Some students employed a sequential and logical approach, while others employed a nebulous, solution centered trial-and-error approach to solving the problem. In this study the participants who were more sequential had better performing solutions. Examining these two approaches and the student cognition data enabled the researcher to generate a conceptual engineering design model for the improved teaching and development of engineering design problem solving.

  14. Towards a Framework for Creative Online Collaboration: A Research on Challenges and Context

    ERIC Educational Resources Information Center

    Stockleben, Björn; Thayne, Martyn; Jäminki, Seija; Haukijärvi, Ilkka; Mavengere, Nicholas Blessing; Demirbilek, Muhammet; Ruohonen, Mikko

    2017-01-01

    The OnCreate project was initiated by ten universities with expertise in collaborative work in online-based learning environments and explores the specific challenges of implementing university courses in creative disciplines in such an environment. The first research phase comprises a literature search on creativity and its contextual factors in…

  15. The Challenge of Teaching Elementary Reading

    ERIC Educational Resources Information Center

    Wolf, Aline D.

    2006-01-01

    In this article, Aline Wolf discusses the challenges of teaching elementary reading at present time. She also raises her concern not only about the declining of reading skills, but also about the declining number of books that students actually read which creates a dilemma for teachers. She believes that the Montessori community must give priority…

  16. Creating Critical Conversations: Investigating the Utility of Socratic Dialogues in Elementary Social Studies Methods

    ERIC Educational Resources Information Center

    Buchanan, Lisa Brown

    2012-01-01

    This article explores the utility of Socratic dialogues in the elementary social studies methods course. Findings include preservice teachers' behaviors during dialogues, perceived strengths and challenges of using Socratic dialogues in teacher education, and the impact on student learning. Challenges and apprehensions encountered by the teacher…

  17. Creating a Pronunciation Profile of First-Year Spanish Students

    ERIC Educational Resources Information Center

    Añorga, Angel; Benander, Ruth

    2015-01-01

    Previous research has shown that improving pronunciation in the foreign language classroom is challenging, and there is often little time left over in a dense curriculum for pronunciation practice. In describing a pronunciation profile for all phonemes in Spanish, this study suggests that the principal challenge for native speakers of English who…

  18. 78 FR 56708 - Announcement of Requirements and Registration for Game On!: HIV/STD Prevention Mobile Application...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-13

    ... Requirements and Registration for Game On!: HIV/ STD Prevention Mobile Application (App) Video Game Challenge... Services (HHS) announces the launch of the Game On!: HIV/STD Prevention Mobile Application (App) Video Game Challenge. We invite video game developers to create an original, innovative, and highly entertaining game...

  19. Cohesion and Trauma: An Examination of a Collegiate Women's Volleyball Team

    ERIC Educational Resources Information Center

    Fletcher, Teresa B.; Meyer, Barbara B.

    2009-01-01

    This study examined the effects of Adventure Based Counseling (i.e., a low-element challenge program) on the cohesion of a collegiate women's volleyball team. Results suggest postintervention improvements in team cohesion. The support created in the challenge experience also transferred to the players helping one another to grieve the untimely…

  20. Creating a Platform for Sustained Neighborhood Improvement: Interim Findings from Chicago's New Communities Program

    ERIC Educational Resources Information Center

    Greenberg, David; Verma, Nandita; Dillman, Keri-Nicole; Chaskin, Robert

    2010-01-01

    Distressed urban neighborhoods face challenges on multiple fronts, but most efforts to confront these problems work in isolation of one another. The New Communities Program (NCP) is an exception, helping selected Chicago neighborhoods develop partnerships to address challenges involving employment, education, housing, and safety in a…

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