Planning for Program Design and Assessment Using Value Creation Frameworks

ERIC Educational Resources Information Center

Whisler, Laurel; Anderson, Rachel; Brown, Jenai

2017-01-01

This article explains a program design and planning process using the Value Creation Framework (VCF) developed by Wenger, Trayner, and de Laat (2011). The framework involves identifying types of value or benefit for those involved in the program, conditions and activities that support creation of that value, data that measure whether the value was…

Up into the Wild Blue Yonder

ERIC Educational Resources Information Center

Pellegrino, Joann

2007-01-01

Children are incredibly interested in the idea of flying and the lesson presented in this article is based on that interest. In this article, the author discusses the creation of a digital presentation that could give an overview of the different types of air travel. Motivational questions teachers can use in their classroom discussions are also…

Imperforate anus repair - series (image)

MedlinePlus

... a high type imperforate anus defect usually involves creation of a temporary opening of the large intestine ( ... includes a fistula) involves closure of the fistula, creation of an anal opening, and repositioning the rectal ...

Cloud based intelligent system for delivering health care as a service.

PubMed

Kaur, Pankaj Deep; Chana, Inderveer

2014-01-01

The promising potential of cloud computing and its convergence with technologies such as mobile computing, wireless networks, sensor technologies allows for creation and delivery of newer type of cloud services. In this paper, we advocate the use of cloud computing for the creation and management of cloud based health care services. As a representative case study, we design a Cloud Based Intelligent Health Care Service (CBIHCS) that performs real time monitoring of user health data for diagnosis of chronic illness such as diabetes. Advance body sensor components are utilized to gather user specific health data and store in cloud based storage repositories for subsequent analysis and classification. In addition, infrastructure level mechanisms are proposed to provide dynamic resource elasticity for CBIHCS. Experimental results demonstrate that classification accuracy of 92.59% is achieved with our prototype system and the predicted patterns of CPU usage offer better opportunities for adaptive resource elasticity. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

A Map-Based Service Supporting Different Types of Geographic Knowledge for the Public

PubMed Central

Zhou, Mengjie; Wang, Rui; Tian, Jing; Ye, Ning; Mai, Shumin

2016-01-01

The internet enables the rapid and easy creation, storage, and transfer of knowledge; however, services that transfer geographic knowledge and facilitate the public understanding of geographic knowledge are still underdeveloped to date. Existing online maps (or atlases) can support limited types of geographic knowledge. In this study, we propose a framework for map-based services to represent and transfer different types of geographic knowledge to the public. A map-based service provides tools to ensure the effective transfer of geographic knowledge. We discuss the types of geographic knowledge that should be represented and transferred to the public, and we propose guidelines and a method to represent various types of knowledge through a map-based service. To facilitate the effective transfer of geographic knowledge, tools such as auxiliary background knowledge and auxiliary map-reading tools are provided through interactions with maps. An experiment conducted to illustrate our idea and to evaluate the usefulness of the map-based service is described; the results demonstrate that the map-based service is useful for transferring different types of geographic knowledge. PMID:27045314

A Map-Based Service Supporting Different Types of Geographic Knowledge for the Public.

PubMed

Zhou, Mengjie; Wang, Rui; Tian, Jing; Ye, Ning; Mai, Shumin

2016-01-01

The internet enables the rapid and easy creation, storage, and transfer of knowledge; however, services that transfer geographic knowledge and facilitate the public understanding of geographic knowledge are still underdeveloped to date. Existing online maps (or atlases) can support limited types of geographic knowledge. In this study, we propose a framework for map-based services to represent and transfer different types of geographic knowledge to the public. A map-based service provides tools to ensure the effective transfer of geographic knowledge. We discuss the types of geographic knowledge that should be represented and transferred to the public, and we propose guidelines and a method to represent various types of knowledge through a map-based service. To facilitate the effective transfer of geographic knowledge, tools such as auxiliary background knowledge and auxiliary map-reading tools are provided through interactions with maps. An experiment conducted to illustrate our idea and to evaluate the usefulness of the map-based service is described; the results demonstrate that the map-based service is useful for transferring different types of geographic knowledge.

The Potential of Research-Based Learning for the Creation of Truly Inclusive Academic Communities of Practice

ERIC Educational Resources Information Center

Smith, Pete; Rust, Chris

2011-01-01

The academic community in higher education is becoming increasingly fragmented, with arguably the greatest fault line between research and teaching. This paper argues that, through the reinvention of the undergraduate curriculum to focus on student engagement in research and research-type activities, a truly inclusive community of academic…

Integration of a Zero-footprint Cloud-based Picture Archiving and Communication System with Customizable Forms for Radiology Research and Education.

PubMed

Hostetter, Jason; Khanna, Nishanth; Mandell, Jacob C

2018-06-01

The purpose of this study was to integrate web-based forms with a zero-footprint cloud-based Picture Archiving and Communication Systems (PACS) to create a tool of potential benefit to radiology research and education. Web-based forms were created with a front-end and back-end architecture utilizing common programming languages including Vue.js, Node.js and MongoDB, and integrated into an existing zero-footprint cloud-based PACS. The web-based forms application can be accessed in any modern internet browser on desktop or mobile devices and allows the creation of customizable forms consisting of a variety of questions types. Each form can be linked to an individual DICOM examination or a collection of DICOM examinations. Several uses are demonstrated through a series of case studies, including implementation of a research platform for multi-reader multi-case (MRMC) studies and other imaging research, and creation of an online Objective Structure Clinical Examination (OSCE) and an educational case file. Copyright © 2018 The Association of University Radiologists. Published by Elsevier Inc. All rights reserved.

"Origin," "creation," and "origin of life" some conceptual considerations.

PubMed

Charpa, Ulrich

2012-01-01

This paper opens by drawing attention to the fact that there is some conceptual confusion with regard to "origin" and "creation." This has its historical roots in the beginnings of modern science and undoubtedly affects our positioning towards the evolutionism/creationism-debate. This article argues that there are relevant ontological, epistemological, thematic, methodological, and logical differences between "origin" and "creation." As a result, the analysis suggests keeping the usage of both concepts strictly quite separate. Creation is not simply another word for origin nor does it stand for an (from a rigid scientific point of view) awkward example of an origin. Irrespective of the apparent similarities as explanatory factors, origin and creation belong to fundamentally different types of concepts. Consequently, "origin of life" and those scientific projects connected to it present themselves as something distinct that neither competes nor meshes with thinking about creation.

Crack Modelling for Radiography

NASA Astrophysics Data System (ADS)

Chady, T.; Napierała, L.

2010-02-01

In this paper, possibility of creation of three-dimensional crack models, both random type and based on real-life radiographic images is discussed. Method for storing cracks in a number of two-dimensional matrices, as well algorithm for their reconstruction into three-dimensional objects is presented. Also the possibility of using iterative algorithm for matching simulated images of cracks to real-life radiographic images is discussed.

A distributed program composition system

NASA Technical Reports Server (NTRS)

Brown, Robert L.

1989-01-01

A graphical technique for creating distributed computer programs is investigated and a prototype implementation is described which serves as a testbed for the concepts. The type of programs under examination is restricted to those comprising relatively heavyweight parts that intercommunicate by passing messages of typed objects. Such programs are often presented visually as a directed graph with computer program parts as the nodes and communication channels as the edges. This class of programs, called parts-based programs, is not well supported by existing computer systems; much manual work is required to describe the program to the system, establish the communication paths, accommodate the heterogeneity of data types, and to locate the parts of the program on the various systems involved. The work described solves most of these problems by providing an interface for describing parts-based programs in this class in a way that closely models the way programmers think about them: using sketches of diagraphs. Program parts, the computational modes of the larger program system are categorized in libraries and are accessed with browsers. The process of programming has the programmer draw the program graph interactively. Heterogeneity is automatically accommodated by the insertion of type translators where necessary between the parts. Many decisions are necessary in the creation of a comprehensive tool for interactive creation of programs in this class. Possibilities are explored and the issues behind such decisions are presented. An approach to program composition is described, not a carefully implemented programming environment. However, a prototype implementation is described that can demonstrate the ideas presented.

Evidence for cosmological particle creation?

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pigozzo, C.; Carneiro, S.; Borges, H.A.

2016-05-01

A joint analysis of the linear matter power spectrum, distance measurements from type Ia supernovae and the position of the first peak in the anisotropy spectrum of the cosmic microwave background indicates a cosmological, late-time dark matter creation at 95% confidence level.

Effects of upper-extremity vascular access creation on cardiac events in patients undergoing coronary artery bypass grafting.

PubMed

Han, Youngjin; Choo, Suk Jung; Kwon, Hyunwook; Lee, Jae Won; Chung, Cheol Hyun; Kim, Hyangkyoung; Kwon, Tae-Won; Cho, Yong-Pil

2017-01-01

The present study was conducted to investigate whether upper-extremity vascular access (VA) creation increases the risk for major adverse cardiac events (MACE) and death in patients undergoing coronary artery bypass grafting (CABG) with an in situ left internal thoracic artery (ITA) graft. A total of 111 patients with CABG with a left ITA graft who underwent upper-extremity VA creation were analyzed retrospectively; 93 patients received left VA creation (83.8%, ipsilateral group) and 18 patients received right VA creation (16.2%, contralateral group). The primary outcome was the occurrence of MACE, and the secondary outcome was the composite of MACE or late death. There were no significant differences in the incidence of primary (P = 0.30) or secondary (P = 0.09) outcomes between the two groups. Multivariate regression analysis indicated that prior cerebrovascular accidents (hazard ratio [HR] 3.30; 95% confidence interval [CI] 1.37-7.97; P = 0.01) and type of VA (HR 3.44; 95% CI 1.34-8.82; P = 0.01) were independently associated with MACE; prior peripheral arterial occlusive disease (HR 4.22; 95% CI 1.62-10.98; P<0.01) and type of VA (arteriovenous fistula vs. prosthetic arteriovenous grafting) (HR 3.06; 95% CI, 1.42-6.61; P<0.01) were associated with the composite of MACE or death. The side and location of VA were not associated with MACE or death. Our study showed no definite evidence that ipsilateral VA creation affects the subsequent occurrence of MACE or late death from any cause. The type of VA (a prosthetic arteriovenous grafting) is a significant predictor of the subsequent occurrence of MACE or late death.

Effects of upper-extremity vascular access creation on cardiac events in patients undergoing coronary artery bypass grafting

PubMed Central

Han, Youngjin; Choo, Suk Jung; Kwon, Hyunwook; Lee, Jae Won; Chung, Cheol Hyun; Kim, Hyangkyoung; Kwon, Tae-Won

2017-01-01

The present study was conducted to investigate whether upper-extremity vascular access (VA) creation increases the risk for major adverse cardiac events (MACE) and death in patients undergoing coronary artery bypass grafting (CABG) with an in situ left internal thoracic artery (ITA) graft. A total of 111 patients with CABG with a left ITA graft who underwent upper-extremity VA creation were analyzed retrospectively; 93 patients received left VA creation (83.8%, ipsilateral group) and 18 patients received right VA creation (16.2%, contralateral group). The primary outcome was the occurrence of MACE, and the secondary outcome was the composite of MACE or late death. There were no significant differences in the incidence of primary (P = 0.30) or secondary (P = 0.09) outcomes between the two groups. Multivariate regression analysis indicated that prior cerebrovascular accidents (hazard ratio [HR] 3.30; 95% confidence interval [CI] 1.37–7.97; P = 0.01) and type of VA (HR 3.44; 95% CI 1.34–8.82; P = 0.01) were independently associated with MACE; prior peripheral arterial occlusive disease (HR 4.22; 95% CI 1.62–10.98; P<0.01) and type of VA (arteriovenous fistula vs. prosthetic arteriovenous grafting) (HR 3.06; 95% CI, 1.42–6.61; P<0.01) were associated with the composite of MACE or death. The side and location of VA were not associated with MACE or death. Our study showed no definite evidence that ipsilateral VA creation affects the subsequent occurrence of MACE or late death from any cause. The type of VA (a prosthetic arteriovenous grafting) is a significant predictor of the subsequent occurrence of MACE or late death. PMID:28873444

Creation of Prototype Aircrew Protection Equipment Based on Face Anthropometry

DTIC Science & Technology

1993-12-01

AD-A273 865 AFIT/GSE/ENY/93D-2AD 27 86 DTIC ELECTE SDE.C 161993 A : CREATION OF PROTOTYPE AIRCREW PROTECTION EQUIPMENT BASED ON FACE ANTHROPOMETRY ...AIRCREW PROTECTION EQUIPMENT BASED ON FACE ANTHROPOMETRY THESIS Presented to the Faculty of the Graduate School of Engineering of the Air Force Institute...trans- form anthropomorphic surfaces into a prototype mask mold. xix CREATION OF PROTOTYPE AIRCREW PROTECTION EQUIPMENT BASED ON FACE ANTHROPOMETRY L

Eugene--a domain specific language for specifying and constraining synthetic biological parts, devices, and systems.

PubMed

Bilitchenko, Lesia; Liu, Adam; Cheung, Sherine; Weeding, Emma; Xia, Bing; Leguia, Mariana; Anderson, J Christopher; Densmore, Douglas

2011-04-29

Synthetic biological systems are currently created by an ad-hoc, iterative process of specification, design, and assembly. These systems would greatly benefit from a more formalized and rigorous specification of the desired system components as well as constraints on their composition. Therefore, the creation of robust and efficient design flows and tools is imperative. We present a human readable language (Eugene) that allows for the specification of synthetic biological designs based on biological parts, as well as provides a very expressive constraint system to drive the automatic creation of composite Parts (Devices) from a collection of individual Parts. We illustrate Eugene's capabilities in three different areas: Device specification, design space exploration, and assembly and simulation integration. These results highlight Eugene's ability to create combinatorial design spaces and prune these spaces for simulation or physical assembly. Eugene creates functional designs quickly and cost-effectively. Eugene is intended for forward engineering of DNA-based devices, and through its data types and execution semantics, reflects the desired abstraction hierarchy in synthetic biology. Eugene provides a powerful constraint system which can be used to drive the creation of new devices at runtime. It accomplishes all of this while being part of a larger tool chain which includes support for design, simulation, and physical device assembly.

Refinement of an Instrument to Assess Readiness for Knowledge Management

DTIC Science & Technology

2007-03-01

knowledge from an Aristotlean view of the five types of knowledge: scientific, skills-based, experiential, intuition and theoretical knowledge of...al., 1999). Other researchers have explored the creation of new knowledge in organizations and a number of theories exist that seek to describe how...Holt, Bartczak, Clark, & Trent, 2004; Prusak, 2001), I am not aware of any comprehensive effort that integrates the fundamental theories of

Meaning creation and employee engagement in home health caregivers.

PubMed

Nielsen, Mette Strange; Jørgensen, Frances

2016-03-01

The purpose of this study is to contribute to an understanding on how home health caregivers experience engagement in their work, and specifically, how aspects of home healthcare work create meaning associated with employee engagement. Although much research on engagement has been conducted, little has addressed how individual differences such as worker orientation influence engagement, or how engagement is experienced within a caregiving context. The study is based on a qualitative study in two home homecare organisations in Denmark using a think-aloud data technique, interviews and observations. The analysis suggests caregivers experience meaning in three relatively distinct ways, depending on their work orientation. Specifically, the nature of engagement varies across caregivers oriented towards being 'nurturers', 'professionals', or 'workers', and the sources of engagement differ for each of these types of caregivers. The article contributes by (i) advancing our theoretical understanding of employee engagement by emphasising meaning creation and (ii) identifying factors that influence meaning creation and engagement of home health caregivers, which should consequently affect the quality of services provided home healthcare patients. © 2015 Nordic College of Caring Science.

Creating Effective Type for the Classroom.

ERIC Educational Resources Information Center

Fitzsimons, Dennis

1989-01-01

Defines basic typographic terminology and offers two classroom projects using microcomputers to create and use type. Discusses typeface, type families, type style, type size, and type font. Examples of student projects that include the creation of bulletin board displays and page-size maps. (KO)

Justification of the Expediency of Creating Circular Intersections in Modern Cities

NASA Astrophysics Data System (ADS)

Vasilyeva, Elena; Sazonova, Tatiana

2017-10-01

The article resumes the principles of driving on Circular Intersections, which causes difficulties for some road users. Referring to certain foreign Traffic regulations, the author points out that such intersections are still stated imprecisely in Traffic regulations. Advantages and disadvantages of circular intersections as well as the expediency of their creation in the cities are considered in the article. The author offers to distinguish several types of circular intersections and claims that the most part of disadvantages listed in the article belong to circular intersections of the old type. On the contrary, the author presumes that creation of modern circular intersections will allow to regulate the planning of cities, make heavy traffic of transport possible while increasing the traffic safety at the same time, to improve the ecological situation of the city as well as its appearance, to carry out energy saving in the transport infrastructure of the city. All these aims could be feasible due to the creation of modern intersections of the Roundabout type.

Knowledge Creation and Innovation in a Civil Engineering Course for the First-Year University Students

ERIC Educational Resources Information Center

Salmisto, Alpo; Nokelainen, Petri

2015-01-01

This article examines the application of knowledge creation learning and innovation to higher education in construction. The objectives are to demonstrate the application of the course based on knowledge creation learning to mass teaching and to analyse whether knowledge creation learning improves student motivation and learning. The empirical…

A combined qualitative-quantitative approach for the identification of highly co-creative technology-driven firms

NASA Astrophysics Data System (ADS)

Milyakov, Hristo; Tanev, Stoyan; Ruskov, Petko

2011-03-01

Value co-creation, is an emerging business and innovation paradigm, however, there is not enough clarity on the distinctive characteristics of value co-creation as compared to more traditional value creation approaches. The present paper summarizes the results from an empirically-derived research study focusing on the development of a systematic procedure for the identification of firms that are active in value co-creation. The study is based on a sample 273 firms that were selected for being representative of the breadth of their value co-creation activities. The results include: i) the identification of the key components of value co-creation based on a research methodology using web search and Principal Component Analysis techniques, and ii) the comparison of two different classification techniques identifying the firms with the highest degree of involvement in value co-creation practices. To the best of our knowledge this is the first study using sophisticated data collection techniques to provide a classification of firms according to the degree of their involvement in value co-creation.

The Seven-Year Plan of Georgia - USSR .

DTIC Science & Technology

1961-08-07

Georgian art. A new pleiad of talented singers, musicians and artists has appeared. At a review of the cultural achievements of Georgia held in Moscow...and gymnastics are favorite types of athletics. The creation of a sport base, of cadres of trainers and teachers makes it possible to train first...account the actual demands of industry. Writers and artists are concluding friendship treaties with enterprises and constructions* The initiative

OmicsNet: a web-based tool for creation and visual analysis of biological networks in 3D space.

PubMed

Zhou, Guangyan; Xia, Jianguo

2018-06-07

Biological networks play increasingly important roles in omics data integration and systems biology. Over the past decade, many excellent tools have been developed to support creation, analysis and visualization of biological networks. However, important limitations remain: most tools are standalone programs, the majority of them focus on protein-protein interaction (PPI) or metabolic networks, and visualizations often suffer from 'hairball' effects when networks become large. To help address these limitations, we developed OmicsNet - a novel web-based tool that allows users to easily create different types of molecular interaction networks and visually explore them in a three-dimensional (3D) space. Users can upload one or multiple lists of molecules of interest (genes/proteins, microRNAs, transcription factors or metabolites) to create and merge different types of biological networks. The 3D network visualization system was implemented using the powerful Web Graphics Library (WebGL) technology that works natively in most major browsers. OmicsNet supports force-directed layout, multi-layered perspective layout, as well as spherical layout to help visualize and navigate complex networks. A rich set of functions have been implemented to allow users to perform coloring, shading, topology analysis, and enrichment analysis. OmicsNet is freely available at http://www.omicsnet.ca.

Using ePortfolio-Based Learning Approach to Facilitate Knowledge Sharing and Creation among College Students

ERIC Educational Resources Information Center

Chang, Chi-Cheng; Chou, Pao-Nan; Liang, Chaoyan

2018-01-01

The purpose of the present study was to examine the effects of the ePortfolio-based learning approach (ePBLA) on knowledge sharing and creation with 92 college students majoring in electrical engineering as the participants. Multivariate analysis of covariance (MANCOVA) with a covariance of pretest on knowledge sharing and creation was conducted…

Building an Effective Interdisciplinary Professional Master's Degree

ERIC Educational Resources Information Center

Kline, Douglas M.; Vetter, Ron; Barnhill, Karen

2013-01-01

This article describes the creation of the Master of Science of Computer Science and Information Systems at University of North Carolina Wilmington. The creation of this graduate degree was funded by the Sloan Foundation as a new type of program, the Professional Master's. The program was designed with significant industry input, and is truly…

Transjugular Intrahepatic Portosystemic Shunt Creation and Variceal Coil or Plug Embolization Ineffectively Attain Gastric Variceal Decompression or Occlusion: Results of a 26-Patient Retrospective Study.

PubMed

Lakhoo, Janesh; Bui, James T; Lokken, R Peter; Ray, Charles E; Gaba, Ron C

2016-07-01

To assess the efficacy of transjugular intrahepatic portosystemic shunt (TIPS) creation with or without variceal coil and/or plug embolization in decompressing or occluding gastric varices (GVs). In this retrospective study, 78 patients with GV bleeding who underwent TIPS creation with or without embolotherapy with metallic coils and/or plugs from 1999 to 2014 were identified. Individuals who had a bare-metal TIPS and/or lacked post-TIPS imaging or endoscopic follow-up were excluded. The final cohort included 26 patients (16 men; median age, 54 y; median Model for End-stage Liver Disease score, 16). Variceal types, supplying vessels, and postprocedure GV patency on cross-sectional imaging or endoscopy were assessed. The primary study outcome measure was GV patency rate as a surrogate for efficacy of TIPS creation with or without embolization. GVs included gastroesophageal varix types 1 (n = 10) and 2 (n = 2), isolated GV types 1 (n = 4) and 2 (n = 2), and unspecified (n = 8). TIPS creation resulted in a median final portosystemic pressure gradient of 7 mm Hg. Multiple GV-supplying vessels (left/posterior/short gastric veins) were present in 65% of patients (n = 17). Embolization was performed in 69% (n = 18). Thirteen, four, and nine patients had imaging, endoscopic, or both imaging/endoscopic follow-up. GV patency rate was 65% (n = 17; 61%/75% with/without embolization) at a median of 128.5 days (range, 1-1,295 d) after TIPS creation. Incidence of recurrent bleeding was 27% (n = 7), and the 90-day mortality rate was 15% (n = 4). In this study, most GVs showed persistent patency despite TIPS decompression and variceal embolization, and the incidence of recurrent bleeding was high. The findings suggest suboptimal efficacy for GVs, and indicate a need for study of alternative or adjunctive approaches to GV treatment, such as chemical obliteration. Copyright © 2016 SIR. Published by Elsevier Inc. All rights reserved.

Creation of learning kits

NASA Technical Reports Server (NTRS)

Stow, D. A.; Estes, J. E.; Mertz, F. C.

1981-01-01

A learning kit is an essential part of any remote sensing workshop, course, or in-house training program to provide the "hands-on" experience of working with remotely sensed imagery. This is the objective of laboratory and field exercises as well as the reason behind the production of imagery/map kits. The way in which these learning kits (containing conventional remotely sensed and collateral data products) are put together is described and some concerns that influence the creation of learning kits are discussed. These include budgetary constraints, number of imagery types, and number of collateral data types.

Recipe creation for automated defect classification with a 450mm surface scanning inspection system based on the bidirectional reflectance distribution function of native defects

NASA Astrophysics Data System (ADS)

Yathapu, Nithin; McGarvey, Steve; Brown, Justin; Zhivotovsky, Alexander

2016-03-01

This study explores the feasibility of Automated Defect Classification (ADC) with a Surface Scanning Inspection System (SSIS). The defect classification was based upon scattering sensitivity sizing curves created via modeling of the Bidirectional Reflectance Distribution Function (BRDF). The BRDF allowed for the creation of SSIS sensitivity/sizing curves based upon the optical properties of both the filmed wafer samples and the optical architecture of the SSIS. The elimination of Polystyrene Latex Sphere (PSL) and Silica deposition on both filmed and bare Silicon wafers prior to SSIS recipe creation and ADC creates a challenge for light scattering surface intensity based defect binning. This study explored the theoretical maximal SSIS sensitivity based on native defect recipe creation in conjunction with the maximal sensitivity derived from BRDF modeling recipe creation. Single film and film stack wafers were inspected with recipes based upon BRDF modeling. Following SSIS recipe creation, initially targeting maximal sensitivity, selected recipes were optimized to classify defects commonly found on non-patterned wafers. The results were utilized to determine the ADC binning accuracy of the native defects and evaluate the SSIS recipe creation methodology. A statistically valid sample of defects from the final inspection results of each SSIS recipe and filmed substrate were reviewed post SSIS ADC processing on a Defect Review Scanning Electron Microscope (SEM). Native defect images were collected from each statistically valid defect bin category/size for SEM Review. The data collected from the Defect Review SEM was utilized to determine the statistical purity and accuracy of each SSIS defect classification bin. This paper explores both, commercial and technical, considerations of the elimination of PSL and Silica deposition as a precursor to SSIS recipe creation targeted towards ADC. Successful integration of SSIS ADC in conjunction with recipes created via BRDF modeling has the potential to dramatically reduce the workload requirements of a Defect Review SEM and save a significant amount of capital expenditure for 450mm SSIS recipe creation.

PubNet: a flexible system for visualizing literature derived networks

PubMed Central

Douglas, Shawn M; Montelione, Gaetano T; Gerstein, Mark

2005-01-01

We have developed PubNet, a web-based tool that extracts several types of relationships returned by PubMed queries and maps them into networks, allowing for graphical visualization, textual navigation, and topological analysis. PubNet supports the creation of complex networks derived from the contents of individual citations, such as genes, proteins, Protein Data Bank (PDB) IDs, Medical Subject Headings (MeSH) terms, and authors. This feature allows one to, for example, examine a literature derived network of genes based on functional similarity. PMID:16168087

Eugene – A Domain Specific Language for Specifying and Constraining Synthetic Biological Parts, Devices, and Systems

PubMed Central

Bilitchenko, Lesia; Liu, Adam; Cheung, Sherine; Weeding, Emma; Xia, Bing; Leguia, Mariana; Anderson, J. Christopher; Densmore, Douglas

2011-01-01

Background Synthetic biological systems are currently created by an ad-hoc, iterative process of specification, design, and assembly. These systems would greatly benefit from a more formalized and rigorous specification of the desired system components as well as constraints on their composition. Therefore, the creation of robust and efficient design flows and tools is imperative. We present a human readable language (Eugene) that allows for the specification of synthetic biological designs based on biological parts, as well as provides a very expressive constraint system to drive the automatic creation of composite Parts (Devices) from a collection of individual Parts. Results We illustrate Eugene's capabilities in three different areas: Device specification, design space exploration, and assembly and simulation integration. These results highlight Eugene's ability to create combinatorial design spaces and prune these spaces for simulation or physical assembly. Eugene creates functional designs quickly and cost-effectively. Conclusions Eugene is intended for forward engineering of DNA-based devices, and through its data types and execution semantics, reflects the desired abstraction hierarchy in synthetic biology. Eugene provides a powerful constraint system which can be used to drive the creation of new devices at runtime. It accomplishes all of this while being part of a larger tool chain which includes support for design, simulation, and physical device assembly. PMID:21559524

Assessing a traditional case-based application exercise and a student question creation exercise on student performance and perceptions.

PubMed

Tatachar, Amulya; Kominski, Carol

2017-07-01

To compare the impact of a traditional case-based application exercise with a student question creation exercise on a) student exam performance, b) student perceptions of enjoyment, competence, understanding, effort, interest in continuing participation, and interest in the subject. Subjects were 84 second-year pharmacy students in a pharmacotherapy course. The research focus was active learning involving the topic of chronic kidney disease-mineral bone disorder. Student teams were randomly assigned to either case-based or student question creation exercises using PeerWise. Student performance was assessed by a pre- and posttest and on block and final exams. After completion, an online survey assessed student perceptions of both exercises. Statistically significant differences were revealed in favor of the student question creation group on enjoyment and interest in the subject matter. No statistically differences were found between the traditional case-based group and the student question creation group on gain score from pre-test to posttest. The student question creation group performed slightly better than the case-based application group on two of the five questions on the block exam but none of these differences reached statistical significance. Students randomly assigned to groups that created and reviewed questions exhibited slightly improved summative exam performance and reported significantly more positive perceptions than students engaging in a more traditional case-based learning activity. Student question creation has demonstrated potential as a useful learning activity. Despite inherent difficulties in designing studies involving educational research in a controlled environment, students who have submitted, created, rated, and answered peers' questions have overall performed well. Copyright © 2017 Elsevier Inc. All rights reserved.

Co-creating value through demand and supply integration in senior industry-observations on 33 senior enterprises in Taiwan.

PubMed

Yang, Ya-Ting; Iqbal, Usman; Chen, Ya-Mei; Su, Shyi; Chang, Yao-Mao; Handa, Yujiro; Lin, Neng-Pai; Hsu, Yi-Hsin Elsa

2016-09-01

With global population aging, great business opportunities are driven by the various needs that the elderly face in everyday living. Internet development makes information spread faster, also allows elderly and their caregivers to more easily access information and actively participate in value co-creation in the services. This study aims to investigate the designs of value co-creation by the supply and demand sides of the senior industry. This study investigated senior industry in Taiwan and analyzed bussiness models of 33 selected successful senior enterprises in 2013. We adopted series field observation, reviews of documentations, analysis of meeting records and in-depth interviews with 65 CEOs and managers. Thirty-three quality enterprises in senior industry. Sixty-five CEOs and managers in 33 senior enterprises. None. Value co-creation design, value co-creating process. We constructed a conceptual model that comprehensively describes essential aspects of value co-creation and categorized the value co-creation designs into four types applying for different business models: (i) interaction in experience spaces co-creation design, (ii) on-site interacting co-creation design, (iii) social networking platform co-creation design and (iv) empowering customers co-creation design. Through value co-creation platform design, the senior enterprises have converted the originally passive roles of the elderly and caregivers into active participants in the value co-creation process. The new paradigm of value co-creation designs not only promote innovative development during the interactive process, lead enterprises reveal and meet customers' needs but also increase markets and profits. © The Author 2016. Published by Oxford University Press in association with the International Society for Quality in Health Care. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

GenePattern | Informatics Technology for Cancer Research (ITCR)

Cancer.gov

GenePattern is a genomic analysis platform that provides access to hundreds of tools for the analysis and visualization of multiple data types. A web-based interface provides easy access to these tools and allows the creation of multi-step analysis pipelines that enable reproducible in silico research. A new GenePattern Notebook environment allows users to combine GenePattern analyses with text, graphics, and code to create complete reproducible research narratives.

Achieving Research Impact Through Co-creation in Community-Based Health Services: Literature Review and Case Study.

PubMed

Greenhalgh, Trisha; Jackson, Claire; Shaw, Sara; Janamian, Tina

2016-06-01

Co-creation-collaborative knowledge generation by academics working alongside other stakeholders-is an increasingly popular approach to aligning research and service development. It has potential for "moving beyond the ivory towers" to deliver significant societal impact via dynamic, locally adaptive community-academic partnerships. Principles of successful co-creation include a systems perspective, a creative approach to research focused on improving human experience, and careful attention to governance and process. If these principles are not followed, co-creation efforts may fail. Co-creation-collaborative knowledge generation by academics working alongside other stakeholders-reflects a "Mode 2" relationship (knowledge production rather than knowledge translation) between universities and society. Co-creation is widely believed to increase research impact. We undertook a narrative review of different models of co-creation relevant to community-based health services. We contrasted their diverse disciplinary roots and highlighted their common philosophical assumptions, principles of success, and explanations for failures. We applied these to an empirical case study of a community-based research-service partnership led by the Centre of Research Excellence in Quality and Safety in Integrated Primary-Secondary Care at the University of Queensland, Australia. Co-creation emerged independently in several fields, including business studies ("value co-creation"), design science ("experience-based co-design"), computer science ("technology co-design"), and community development ("participatory research"). These diverse models share some common features, which were also evident in the case study. Key success principles included (1) a systems perspective (assuming emergence, local adaptation, and nonlinearity); (2) the framing of research as a creative enterprise with human experience at its core; and (3) an emphasis on process (the framing of the program, the nature of relationships, and governance and facilitation arrangements, especially the style of leadership and how conflict is managed). In both the literature review and the case study, co-creation "failures" could often be tracked back to abandoning (or never adopting) these principles. All co-creation models made strong claims for significant and sustainable societal impacts as a result of the adaptive and developmental research process; these were illustrated in the case study. Co-creation models have high potential for societal impact but depend critically on key success principles. To capture the nonlinear chains of causation in the co-creation pathway, impact metrics must reflect the dynamic nature and complex interdependencies of health research systems and address processes as well as outcomes. © 2016 Milbank Memorial Fund.

Space Creation Dynamics in Basketball Small-Sided Games.

PubMed

Bredt, Sarah G T; Morales, Juan C P; Andrade, André G P; Torres, Juliana O; Peixoto, Gustavo H; Greco, Pablo J; Praça, Gibson M; Chagas, Mauro H

2018-02-01

Space creation dynamics (SCDs) describe actions players perform to create a scoring opportunity. This study compared SCDs and types of offense during three different three versus three (3vs.3) basketball small-sided games (SSGs) played in half court: 3vs.3 with man-to-man defense in half playing area (3vs.3 HALF ), 3vs.3 with man-to-man defense in full playing area (3vs.3 FULL ), and 3vs.3 with reduced shot clock (3vs.3 RT ). We also investigated the efficacy of SCDs in all SSGs and the reliability of SCDs in 3vs.3 HALF . While the efficacy of SCDs did not differ among these SSGs, 3vs.3 RT presented significantly more "space creation with ball dribbled" and "shot clock violations," and less "on ball screens." 3vs.3 FULL presented no differences in the SCDs and types of offense compared with 3vs.3 HALF . Reliability within 3vs.3 HALF was higher for "space creation with ball dribbled," "space creation without the ball," "set offenses," "fast breaks," and "loss of ball during passing or dribbling." We concluded that 3vs.3 basketball SSGs with different rules can be used for training different tactical behaviors important to formal games, especially since the 3vs.3 HALF presented good reliability for many variables related to tactical behavior.

"Smoking Is Sóóó ... Sandals and White Socks": Co-Creation of a Dutch Anti-Smoking Campaign to Change Social Norms.

PubMed

van den Heerik, Romy A M; van Hooijdonk, Charlotte M J; Burgers, Christian; Steen, Gerard J

2017-05-01

This article considers co-creation as a new persuasive strategy in health campaigns. Co-creation enables target audience members to become active campaign producers. A recent Dutch anti-smoking campaign applied co-creation, inviting the target audience to complete the slogan "smoking is sóóó . . . " with something outdated on social networking sites (SNSs) like Facebook and Twitter to stress non-smoking as the new social norm. From a corpus-linguistic perspective, we investigated how the slogans from the target audience resonated with or deviated from the campaign's original message. In general, the target audience slogans followed the campaign's approach, but on the SNSs, differences were found regarding the valence, type of utterance, and domain to which smoking was compared. The target audience frequently compared smoking with other (inter)personal social norms. Co-creation thus provides the target audience with an opportunity to disseminate campaign messages from their own perspective, but at the same time a co-creation strategy risks diluting the intended campaign message.

Measures to Combat Research Phobia among Undergraduates for Knowledge Creation in Imo State

ERIC Educational Resources Information Center

Ihebereme, Chioma I.

2012-01-01

The study examined the measures to combat research phobia among undergraduates in order to achieve knowledge creation. The study used Alvan Ikoku Federal College of Education Owerri in Imo State as case study. An 11-item four point Likert-type scale of Agreed (A) = 4 points, Strongly Agreed (SA) = 3 points, Disagreed (D) = 2 points and Strongly…

IntegratedMap: a Web interface for integrating genetic map data.

PubMed

Yang, Hongyu; Wang, Hongyu; Gingle, Alan R

2005-05-01

IntegratedMap is a Web application and database schema for storing and interactively displaying genetic map data. Its Web interface includes a menu for direct chromosome/linkage group selection, a search form for selection based on mapped object location and linkage group displays. An overview display provides convenient access to the full range of mapped and anchored object types with genetic locus details, such as numbers, types and names of mapped/anchored objects displayed in a compact scrollable list box that automatically updates based on selected map location and object type. Also, multilinkage group and localized map views are available along with links that can be configured for integration with other Web resources. IntegratedMap is implemented in C#/ASP.NET and the package, including a MySQL schema creation script, is available from http://cggc.agtec.uga.edu/Data/download.asp

Wandering: A Web-Based Platform for the Creation of Location-Based Interactive Learning Objects

ERIC Educational Resources Information Center

Barak, Miri; Ziv, Shani

2013-01-01

Wandering is an innovative web-based platform that was designed to facilitate outdoor, authentic, and interactive learning via the creation of location-based interactive learning objects (LILOs). Wandering was integrated as part of a novel environmental education program among middle school students. This paper describes the Wandering platform's…

Supporting telemicroscopy and laboratory medicine activities. The Greek "TELE.INFO.MED.LAB" project.

PubMed

Miaoulis, G; Protopapa, E; Skourlas, C; Delides, G

1995-01-01

In this paper the authors present the basic results of the study for the "TELE.INFO.MED.LAB" project. This study is based on the local experience of the Metaxas Cancer Institute case and on international references. The possibilities rendered by current developments in telemedicine and particularly in telepathology accelerate and facilitate the communication of crucial medical data and creation of "second level" medical services overcoming the geographical particularities of the country. The availability of data transmission (signals, images, texts, etc.) enables the creation of a "uniform market" for various services. This system must take into account the financial realities, geographical aspects transportation problems and technological developments. Organization of this system, the choices of technical standards and the realization of a complete pilot project are described. For this system we also describe the functional and technical aspects, as well as software and hardware components for the different types of units.

Tuning the Fabrication of Nanostructures by Low-Energy Highly Charged Ions.

PubMed

El-Said, Ayman S; Wilhelm, Richard A; Heller, Rene; Sorokin, Michael; Facsko, Stefan; Aumayr, Friedrich

2016-09-16

Slow highly charged ions have been utilized recently for the creation of monotype surface nanostructures (craters, calderas, or hillocks) in different materials. In the present study, we report on the ability of slow highly charged xenon ions (^{129}Xe^{Q+}) to form three different types of nanostructures on the LiF(100) surface. By increasing the charge state from Q=15 to Q=36, the shape of the impact induced nanostructures changes from craters to hillocks crossing an intermediate stage of caldera structures. A dimensional analysis of the nanostructures reveals an increase of the height up to 1.5 nm as a function of the potential energy of the incident ions. Based on the evolution of both the geometry and size of the created nanostructures, defect-mediated desorption and the development of a thermal spike are utilized as creation mechanisms of the nanostructures at low and high charge states, respectively.

Capturing farm diversity with hypothesis-based typologies: An innovative methodological framework for farming system typology development

PubMed Central

Alvarez, Stéphanie; Timler, Carl J.; Michalscheck, Mirja; Paas, Wim; Descheemaeker, Katrien; Tittonell, Pablo; Andersson, Jens A.; Groot, Jeroen C. J.

2018-01-01

Creating typologies is a way to summarize the large heterogeneity of smallholder farming systems into a few farm types. Various methods exist, commonly using statistical analysis, to create these typologies. We demonstrate that the methodological decisions on data collection, variable selection, data-reduction and clustering techniques can bear a large impact on the typology results. We illustrate the effects of analysing the diversity from different angles, using different typology objectives and different hypotheses, on typology creation by using an example from Zambia’s Eastern Province. Five separate typologies were created with principal component analysis (PCA) and hierarchical clustering analysis (HCA), based on three different expert-informed hypotheses. The greatest overlap between typologies was observed for the larger, wealthier farm types but for the remainder of the farms there were no clear overlaps between typologies. Based on these results, we argue that the typology development should be guided by a hypothesis on the local agriculture features and the drivers and mechanisms of differentiation among farming systems, such as biophysical and socio-economic conditions. That hypothesis is based both on the typology objective and on prior expert knowledge and theories of the farm diversity in the study area. We present a methodological framework that aims to integrate participatory and statistical methods for hypothesis-based typology construction. This is an iterative process whereby the results of the statistical analysis are compared with the reality of the target population as hypothesized by the local experts. Using a well-defined hypothesis and the presented methodological framework, which consolidates the hypothesis through local expert knowledge for the creation of typologies, warrants development of less subjective and more contextualized quantitative farm typologies. PMID:29763422

Capturing farm diversity with hypothesis-based typologies: An innovative methodological framework for farming system typology development.

PubMed

Alvarez, Stéphanie; Timler, Carl J; Michalscheck, Mirja; Paas, Wim; Descheemaeker, Katrien; Tittonell, Pablo; Andersson, Jens A; Groot, Jeroen C J

2018-01-01

Creating typologies is a way to summarize the large heterogeneity of smallholder farming systems into a few farm types. Various methods exist, commonly using statistical analysis, to create these typologies. We demonstrate that the methodological decisions on data collection, variable selection, data-reduction and clustering techniques can bear a large impact on the typology results. We illustrate the effects of analysing the diversity from different angles, using different typology objectives and different hypotheses, on typology creation by using an example from Zambia's Eastern Province. Five separate typologies were created with principal component analysis (PCA) and hierarchical clustering analysis (HCA), based on three different expert-informed hypotheses. The greatest overlap between typologies was observed for the larger, wealthier farm types but for the remainder of the farms there were no clear overlaps between typologies. Based on these results, we argue that the typology development should be guided by a hypothesis on the local agriculture features and the drivers and mechanisms of differentiation among farming systems, such as biophysical and socio-economic conditions. That hypothesis is based both on the typology objective and on prior expert knowledge and theories of the farm diversity in the study area. We present a methodological framework that aims to integrate participatory and statistical methods for hypothesis-based typology construction. This is an iterative process whereby the results of the statistical analysis are compared with the reality of the target population as hypothesized by the local experts. Using a well-defined hypothesis and the presented methodological framework, which consolidates the hypothesis through local expert knowledge for the creation of typologies, warrants development of less subjective and more contextualized quantitative farm typologies.

Computer Assisted Multi-Center Creation of Medical Knowledge Bases

PubMed Central

Giuse, Nunzia Bettinsoli; Giuse, Dario A.; Miller, Randolph A.

1988-01-01

Computer programs which support different aspects of medical care have been developed in recent years. Their capabilities range from diagnosis to medical imaging, and include hospital management systems and therapy prescription. In spite of their diversity these systems have one commonality: their reliance on a large body of medical knowledge in computer-readable form. This knowledge enables such programs to draw inferences, validate hypotheses, and in general to perform their intended task. As has been clear to developers of such systems, however, the creation and maintenance of medical knowledge bases are very expensive. Practical and economical difficulties encountered during this long-term process have discouraged most attempts. This paper discusses knowledge base creation and maintenance, with special emphasis on medical applications. We first describe the methods currently used and their limitations. We then present our recent work on developing tools and methodologies which will assist in the process of creating a medical knowledge base. We focus, in particular, on the possibility of multi-center creation of the knowledge base.

Spin Transport in Nondegenerate Si with a Spin MOSFET Structure at Room Temperature

NASA Astrophysics Data System (ADS)

Sasaki, Tomoyuki; Ando, Yuichiro; Kameno, Makoto; Tahara, Takayuki; Koike, Hayato; Oikawa, Tohru; Suzuki, Toshio; Shiraishi, Masashi

2014-09-01

Spin transport in nondegenerate semiconductors is expected to pave the way to the creation of spin transistors, spin logic devices, and reconfigurable logic circuits, because room-temperature (RT) spin transport in Si has already been achieved. However, RT spin transport has been limited to degenerate Si, which makes it difficult to produce spin-based signals because a gate electric field cannot be used to manipulate such signals. Here, we report the experimental demonstration of spin transport in nondegenerate Si with a spin metal-oxide-semiconductor field-effect transistor (MOSFET) structure. We successfully observe the modulation of the Hanle-type spin-precession signals, which is a characteristic spin dynamics in nondegenerate semiconductors. We obtain long spin transport of more than 20 μm and spin rotation greater than 4π at RT. We also observe gate-induced modulation of spin-transport signals at RT. The modulation of the spin diffusion length as a function of a gate voltage is successfully observed, which we attribute to the Elliott-Yafet spin relaxation mechanism. These achievements are expected to lead to the creation of practical Si-based spin MOSFETs.

Knowledge-Based Transformational Synthesis of Efficient Structures for Concurrent Computation.

DTIC Science & Technology

1985-09-30

this wire network to a smaller wire network , creation of subnetworks to replace an overly-broad fanout network , virtualization which is the creation of...dependencies among the values they contain, reduction of this wire network to a smaller wire network , " creation of subnetworks to replace an overly-broad...fanout network , "rtualization which is the creation of additional array elements and processors to reflect the internal enumera- -4 tions that

Does Teaching Creationism Facilitate Student Autonomy?

ERIC Educational Resources Information Center

Warnick, Bryan R.; Fooce, C. David

2007-01-01

The teaching of evolution in US public schools continues to generate controversy. One argument for including creationism in science classrooms is based on the goal of facilitating student autonomy. Autonomy requires that students be exposed to significant alternatives, it is argued, and religious creation stories offer a significant alternative to…

Enhanced Uranium Ore Concentrate Analysis by Handheld Raman Sensor: FY15 Status Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bryan, Samuel A.; Johnson, Timothy J.; Orton, Christopher R.

2015-11-11

High-purity uranium ore concentrates (UOC) represent a potential proliferation concern. A cost-effective, “point and shoot” in-field analysis capability to identify ore types, phases of materials present, and impurities, as well as estimate the overall purity would be prudent. Handheld, Raman-based sensor systems are capable of identifying chemical properties of liquid and solid materials. While handheld Raman systems have been extensively applied to many other applications, they have not been broadly studied for application to UOC, nor have they been optimized for this class of chemical compounds. PNNL was tasked in Fiscal Year 2015 by the Office of International Safeguards (NA-241)more » to explore the use of Raman for UOC analysis and characterization. This report summarizes the activities in FY15 related to this project. The following tasks were included: creation of an expanded library of Raman spectra of a UOC sample set, creation of optimal chemometric analysis methods to classify UOC samples by their type and level of impurities, and exploration of the various Raman wavelengths to identify the ideal instrument settings for UOC sample interrogation.« less

[The Seintinelles: an innovative approach to promoting Community-Based Research and sustaining health democracy in oncology].

PubMed

Bauquier, Charlotte; Pannard, Myriam; Préau, Marie

2017-10-02

Community-based research drives innovation in major fields of public health, HIV/AIDS being the most emblematic example (Demange, Henry & Préau, 2012), and hepatitis. However, this type of research appears to be more difficult to develop in certain specific diseases, such as cancer (Shankand, Saïas & Friboulet, 2009). This article proposes various approaches concerning current citizen mobilization in relation to cancer research, including potential new levers to the development of participative and community-based research based on the recent creation of the Seintinelles platform, designed to federate researchers and citizens concerned by the problem of cancer. This reflection will be supported by more global issues concerning health democracy.

Pattern-based information portal for business plan co-creation

NASA Astrophysics Data System (ADS)

Bontchev, Boyan; Ruskov, Petko; Tanev, Stoyan

2011-03-01

Creation of business plans helps entrepreneurs in managing identification of business opportunities and committing necessary resources for process evolution. Applying patterns in business plan creation facilitates the identification of effective solutions that were adopted in the past and may provide a basis for adopting similar solutions in the future within given business context. The article presents the system design of an information portal for business plan co-creation based on patterns. The portal is going to provide start-up and entrepreneurs with ready-to-modify business plan patterns in order to help them in development of effective and efficient business plans. It will facilitate entrepreneurs in co-experimenting and co-learning more frequently and faster. Moreover, the paper focuses on the software architecture of the pattern based portal and explains the functionality of its modules, namely the pattern designer, pattern repository services and agent-based pattern implementers. It explains their role for business process co-creation, storing and managing patterns described formally, and selecting patterns best suited for specific business case. Thus, innovative entrepreneurs will be guided by the portal in co-writing winning business plans and staying competitive in the present day dynamic globalized environment.

Pattern-based information portal for business plan co-creation

NASA Astrophysics Data System (ADS)

Bontchev, Boyan; Ruskov, Petko; Tanev, Stoyan

2010-10-01

Creation of business plans helps entrepreneurs in managing identification of business opportunities and committing necessary resources for process evolution. Applying patterns in business plan creation facilitates the identification of effective solutions that were adopted in the past and may provide a basis for adopting similar solutions in the future within given business context. The article presents the system design of an information portal for business plan co-creation based on patterns. The portal is going to provide start-up and entrepreneurs with ready-to-modify business plan patterns in order to help them in development of effective and efficient business plans. It will facilitate entrepreneurs in co-experimenting and co-learning more frequently and faster. Moreover, the paper focuses on the software architecture of the pattern based portal and explains the functionality of its modules, namely the pattern designer, pattern repository services and agent-based pattern implementers. It explains their role for business process co-creation, storing and managing patterns described formally, and selecting patterns best suited for specific business case. Thus, innovative entrepreneurs will be guided by the portal in co-writing winning business plans and staying competitive in the present day dynamic globalized environment.

Proposal for creation of a new genus Neomicrococcus gen. nov. to accommodate Zhihengliuella aestuarii Baik et al. 2011 and Micrococcus lactis Chittpurna et al. 2011 as Neomicrococcus aestuarii comb. nov. and Neomicrococcus lactis comb. nov.

PubMed

Prakash, Om; Sharma, Avinash; Nimonkar, Yogesh; Shouche, Yogesh S

2015-11-01

Micrococcus lactis and Zhihengliuella aestuarii were described independently in 2011. Their type strains showed high levels of 16S rRNA gene sequence similarity (99.3%). Phylogenetic analysis revealed that M. lactis MCC 2278T and Z. aestuarii JCM 16166T formed a monophyletic group and showed distant relationships to other members of closely related genera such as Micrococcus, Zhihengliuella, Arthrobacter and Citricoccus. The presence of large proportions of iso-C14:0 and iso-C16:0 with small amounts of iso-C15:0 distinguished M. lactis MCC 2278T and Z. aestuarii JCM 16166T from other members of the genera Micrococcus and Zhihengliuella. Unlike other members of the genera Zhihengliuella and Micrococcus, M. lactis MCC 2278T and Z. aestuarii JCM 16166T showed growth at low concentrations of NaCl. Thus, based on distinctive phylogenetic, chemotaxonomic and physiological features of these two organisms in comparison with other members of the genera Micrococcus and Zhihengliuella, it is clear that they do not fit within the existing classification and deserve separate status. DNA-DNA hybridization between the two type strains was 63%, indicating that they represent separate species. In this study, we propose the creation of a novel genus, Neomicrococcus gen. nov., to accommodate the two species with Neomicrococcus aestuarii gen. nov., comb. nov. (type strain JCM 16166T = KCTC 19557T) as the type species. Neomicrococcus lactis comb. nov. (type strain MCC 2278T = DSM 23694T) is also proposed.

The creation of high-temperature superconducting cables of megawatt range in Russia

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sytnikov, V. E., E-mail: vsytnikov@gmail.com; Bemert, S. E.; Krivetsky, I. V.

Urgent problems of the power industry in the 21st century require the creation of smart energy systems, providing a high effectiveness of generation, transmission, and consumption of electric power. Simultaneously, the requirements for controllability of power systems and ecological and resource-saving characteristics at all stages of production and distribution of electric power are increased. One of the decision methods of many problems of the power industry is the development of new high-efficiency electrical equipment for smart power systems based on superconducting technologies to ensure a qualitatively new level of functioning of the electric power industry. The intensive research and developmentmore » of new types of electrical devices based on superconductors are being carried out in many industrialized advanced countries. Interest in such developments has especially increased in recent years owing to the discovery of so-called high-temperature superconductors (HTS) that do not require complicated and expensive cooling devices. Such devices can operate at cooling by inexpensive and easily accessible liquid nitrogen. Taking into account the obvious advantages of superconducting cable lines for the transmission of large power flows through an electrical network, as compared with conventional cables, the Federal Grid Company of Unified Energy System (JSC FGC UES) initiated a research and development program including the creation of superconducting HTS AC and DC cable lines. Two cable lines for the transmitted power of 50 MVA/MW at 20 kV were manufactured and tested within the framework of the program.« less

The creation of high-temperature superconducting cables of megawatt range in Russia

NASA Astrophysics Data System (ADS)

Sytnikov, V. E.; Bemert, S. E.; Krivetsky, I. V.; Romashov, M. A.; Popov, D. A.; Fedotov, E. V.; Komandenko, O. V.

2015-12-01

Urgent problems of the power industry in the 21st century require the creation of smart energy systems, providing a high effectiveness of generation, transmission, and consumption of electric power. Simultaneously, the requirements for controllability of power systems and ecological and resource-saving characteristics at all stages of production and distribution of electric power are increased. One of the decision methods of many problems of the power industry is the development of new high-efficiency electrical equipment for smart power systems based on superconducting technologies to ensure a qualitatively new level of functioning of the electric power industry. The intensive research and development of new types of electrical devices based on superconductors are being carried out in many industrialized advanced countries. Interest in such developments has especially increased in recent years owing to the discovery of so-called high-temperature superconductors (HTS) that do not require complicated and expensive cooling devices. Such devices can operate at cooling by inexpensive and easily accessible liquid nitrogen. Taking into account the obvious advantages of superconducting cable lines for the transmission of large power flows through an electrical network, as compared with conventional cables, the Federal Grid Company of Unified Energy System (JSC FGC UES) initiated a research and development program including the creation of superconducting HTS AC and DC cable lines. Two cable lines for the transmitted power of 50 MVA/MW at 20 kV were manufactured and tested within the framework of the program.

Creation of a type IIS restriction endonuclease with a long recognition sequence

PubMed Central

Lippow, Shaun M.; Aha, Patti M.; Parker, Matthew H.; Blake, William J.; Baynes, Brian M.; Lipovšek, Daša

2009-01-01

Type IIS restriction endonucleases cleave DNA outside their recognition sequences, and are therefore particularly useful in the assembly of DNA from smaller fragments. A limitation of type IIS restriction endonucleases in assembly of long DNA sequences is the relative abundance of their target sites. To facilitate ligation-based assembly of extremely long pieces of DNA, we have engineered a new type IIS restriction endonuclease that combines the specificity of the homing endonuclease I-SceI with the type IIS cleavage pattern of FokI. We linked a non-cleaving mutant of I-SceI, which conveys to the chimeric enzyme its specificity for an 18-bp DNA sequence, to the catalytic domain of FokI, which cuts DNA at a defined site outside the target site. Whereas previously described chimeric endonucleases do not produce type IIS-like precise DNA overhangs suitable for ligation, our chimeric endonuclease cleaves double-stranded DNA exactly 2 and 6 nt from the target site to generate homogeneous, 5′, four-base overhangs, which can be ligated with 90% fidelity. We anticipate that these enzymes will be particularly useful in manipulation of DNA fragments larger than a thousand bases, which are very likely to contain target sites for all natural type IIS restriction endonucleases. PMID:19304757

Strategies for Directing the Structure and Function of 3D Collagen Biomaterials across Length Scales

PubMed Central

Walters, Brandan D.; Stegemann, Jan P.

2013-01-01

Collagen type I is a widely used natural biomaterial that has found utility in a variety of biological and medical applications. Its well characterized structure and role as an extracellular matrix protein make it a highly relevant material for controlling cell function and mimicking tissue properties. Collagen type I is abundant in a number of tissues, and can be isolated as a purified protein. This review focuses on hydrogel biomaterials made by reconstituting collagen type I from a solubilized form, with an emphasis on in vitro studies in which collagen structure can be controlled. The hierarchical structure of collagen from the nanoscale to the macroscale is described, with an emphasis on how structure is related to function across scales. Methods of reconstituting collagen into hydrogel materials are presented, including molding of macroscopic constructs, creation of microscale modules, and electrospinning of nanoscale fibers. The modification of collagen biomaterials to achieve desired structures and functions is also addressed, with particular emphasis on mechanical control of collagen structure, creation of collagen composite materials, and crosslinking of collagenous matrices. Biomaterials scientists have made remarkable progress in rationally designing collagen-based biomaterials and in applying them to both the study of biology and for therapeutic benefit. This broad review illustrates recent examples of techniques used to control collagen structure, and to thereby direct its biological and mechanical functions. PMID:24012608

Superconducting dark energy

NASA Astrophysics Data System (ADS)

Liang, Shi-Dong; Harko, Tiberiu

2015-04-01

Based on the analogy with superconductor physics we consider a scalar-vector-tensor gravitational model, in which the dark energy action is described by a gauge invariant electromagnetic type functional. By assuming that the ground state of the dark energy is in a form of a condensate with the U(1) symmetry spontaneously broken, the gauge invariant electromagnetic dark energy can be described in terms of the combination of a vector and of a scalar field (corresponding to the Goldstone boson), respectively. The gravitational field equations are obtained by also assuming the possibility of a nonminimal coupling between the cosmological mass current and the superconducting dark energy. The cosmological implications of the dark energy model are investigated for a Friedmann-Robertson-Walker homogeneous and isotropic geometry for two particular choices of the electromagnetic type potential, corresponding to a pure electric type field, and to a pure magnetic field, respectively. The time evolutions of the scale factor, matter energy density and deceleration parameter are obtained for both cases, and it is shown that in the presence of the superconducting dark energy the Universe ends its evolution in an exponentially accelerating vacuum de Sitter state. By using the formalism of the irreversible thermodynamic processes for open systems we interpret the generalized conservation equations in the superconducting dark energy model as describing matter creation. The particle production rates, the creation pressure and the entropy evolution are explicitly obtained.

XML-based information system for planetary sciences

NASA Astrophysics Data System (ADS)

Carraro, F.; Fonte, S.; Turrini, D.

2009-04-01

EuroPlaNet (EPN in the following) has been developed by the planetological community under the "Sixth Framework Programme" (FP6 in the following), the European programme devoted to the improvement of the European research efforts through the creation of an internal market for science and technology. The goal of the EPN programme is the creation of a European network aimed to the diffusion of data produced by space missions dedicated to the study of the Solar System. A special place within the EPN programme is that of I.D.I.S. (Integrated and Distributed Information Service). The main goal of IDIS is to offer to the planetary science community a user-friendly access to the data and information produced by the various types of research activities, i.e. Earth-based observations, space observations, modeling, theory and laboratory experiments. During the FP6 programme IDIS development consisted in the creation of a series of thematic nodes, each of them specialized in a specific scientific domain, and a technical coordination node. The four thematic nodes are the Atmosphere node, the Plasma node, the Interiors & Surfaces node and the Small Bodies & Dust node. The main task of the nodes have been the building up of selected scientific cases related with the scientific domain of each node. The second work done by EPN nodes have been the creation of a catalogue of resources related to their main scientific theme. Both these efforts have been used as the basis for the development of the main IDIS goal, i.e. the integrated distributed service. An XML-based data model have been developed to describe resources using meta-data and to store the meta-data within an XML-based database called eXist. A search engine has been then developed in order to allow users to search resources within the database. Users can select the resource type and can insert one or more values or can choose a value among those present in a list, depending on selected resource. The system searches for all the resources containing the inserted values within the resources descriptions. An important facility of the IDIS search system is the multi-node search capability. This is due to the capacity of eXist to make queries on remote databases. This allows the system to show all resources which satisfy the search criteria on local node and to show how many resources are found on remote nodes, giving also a link to open the results page on remote nodes. During FP7 the development of the IDIS system will have the main goal to make the service Virtual Observatory compliant.

An Efficacious Measurement of Learning Initiatives: E-Learning Systems, Learning-Organization Culture, Knowledge Creation, and Innovativeness

ERIC Educational Resources Information Center

Grundhoefer, Raymie

2013-01-01

The purpose of this research is twofold: (a) develop a validated measure for learning initiatives based on knowledge-creation theory and (b) conduct a quantitative study to investigate the relationships between electronic learning systems, learning-organization culture, efficacious knowledge creation (EKC), and innovativeness. Although Cheng-Chang…

Social media addiction: What is the role of content in YouTube?

PubMed Central

Balakrishnan, Janarthanan; Griffiths, Mark D.

2017-01-01

Background YouTube, the online video creation and sharing site, supports both video content viewing and content creation activities. For a minority of people, the time spent engaging with YouTube can be excessive and potentially problematic. Method This study analyzed the relationship between content viewing, content creation, and YouTube addiction in a survey of 410 Indian-student YouTube users. It also examined the influence of content, social, technology, and process gratifications on user inclination toward YouTube content viewing and content creation. Results The results demonstrated that content creation in YouTube had a closer relationship with YouTube addiction than content viewing. Furthermore, social gratification was found to have a significant influence on both types of YouTube activities, whereas technology gratification did not significantly influence them. Among all perceived gratifications, content gratification had the highest relationship coefficient value with YouTube content creation inclination. The model fit and variance extracted by the endogenous constructs were good, which further validated the results of the analysis. Conclusion The study facilitates new ways to explore user gratification in using YouTube and how the channel responds to it. PMID:28914072

Social media addiction: What is the role of content in YouTube?

PubMed

Balakrishnan, Janarthanan; Griffiths, Mark D

2017-09-01

Background YouTube, the online video creation and sharing site, supports both video content viewing and content creation activities. For a minority of people, the time spent engaging with YouTube can be excessive and potentially problematic. Method This study analyzed the relationship between content viewing, content creation, and YouTube addiction in a survey of 410 Indian-student YouTube users. It also examined the influence of content, social, technology, and process gratifications on user inclination toward YouTube content viewing and content creation. Results The results demonstrated that content creation in YouTube had a closer relationship with YouTube addiction than content viewing. Furthermore, social gratification was found to have a significant influence on both types of YouTube activities, whereas technology gratification did not significantly influence them. Among all perceived gratifications, content gratification had the highest relationship coefficient value with YouTube content creation inclination. The model fit and variance extracted by the endogenous constructs were good, which further validated the results of the analysis. Conclusion The study facilitates new ways to explore user gratification in using YouTube and how the channel responds to it.

Systematic revision of the adeleid haemogregarines, with creation of Bartazoon n. g., reassignment of Hepatozoon argantis Garnham, 1954 to Hemolivia, and molecular data on Hemolivia stellata

PubMed Central

Karadjian, Grégory; Chavatte, Jean-Marc; Landau, Irène

2015-01-01

Life cycles and molecular data for terrestrial haemogregarines are reviewed in this article. Collection material was re-examined: Hepatozoon argantis Garnham, 1954 in Argas brumpti was reassigned to Hemolivia as Hemolivia argantis (Garnham, 1954) n. comb.; parasite DNA was extracted from a tick crush on smear of an archived slide of Hemolivia stellata in Amblyomma rotondatum, then the 18S ssrRNA gene was amplified by PCR. A systematic revision of the group is proposed, based on biological life cycles and phylogenetic reconstruction. Four types of life cycles, based on parasite vector, vertebrate host and the characteristics of their development, are defined. We propose combining species, based on their biology, into four groups (types I, II, III and IV). The characters of each type are defined and associated with a type genus and a type species. The biological characters of each type are associated with a different genus and a type species. The phylogenetic reconstruction with sequences deposited in the databases and our own new sequence of Hemolivia stellata is consistent with this classification. The classification is as follows: Type I, Hepatozoon Miller, 1908, type species H. perniciosum Miller, 1908; Type II, Karyolysus Labbé, 1894, type species K. lacertae (Danilewsky, 1886) Reichenow, 1913; Type III Hemolivia Petit et al., 1990, type species H. stellata, Petit et al., 1990; and Type IV: Bartazoon n. g., type species B. breinli (Mackerras, 1960). PMID:26551414

Development of a booklet on insulin therapy for children with diabetes mellitus type 1.

PubMed

Moura, Denizielle de Jesus Moreira; Moura, Nádya Dos Santos; Menezes, Luciana Catunda Gomes de; Barros, Ariane Alves; Guedes, Maria Vilani Cavalcante

2017-01-01

to describe the process of developing of an educational booklet on insulin therapy for children with diabetes mellitus type 1. methodological approach, in which the following steps were carried out: selecting of the content and type of technology to be developed (for this step, an integrative review, an analysis of the comments of blogs about Diabetes Mellitus type 1 and interviews with the children were performed), creation of images, formatting and layout composition. the work resulted in the production of the final version of the educational booklet, which was titled Aplicando a insulina: a aventura de Beto [Applying insulin: Beto's adventure]. The process of developing of the booklet was based on the active participation of the children and guided by the theoretical framework of Piagetian Constructivism. the resource is a facilitator for the improvement of the knowledge and practices of self care of children with Diabetes Mellitus type 1.

An evidence-based approach to the creation of normative data: base rates of impaired scores within a brief neuropsychological battery argue for age corrections, but against corrections for medical conditions.

PubMed

O'Connell, Megan E; Tuokko, Holly; Voll, Stacey; Simard, Martine; Griffith, Lauren E; Taler, Vanessa; Wolfson, Christina; Kirkland, Susan; Raina, Parminder

We detail a new approach to the creation of normative data for neuropsychological tests. The traditional approach to normative data creation is to make demographic adjustments based on observations of correlations between single neuropsychological tests and selected demographic variables. We argue, however, that this does not describe the implications for clinical practice, such as increased likelihood of misclassification of cognitive impairment, nor does it elucidate the impact on decision-making with a neuropsychological battery. We propose base rate analyses; specifically, differential base rates of impaired scores between theoretical and actual base rates as the basis for decisions to create demographic adjustments within normative data. Differential base rates empirically describe the potential clinical implications of failing to create an appropriate normative group. We demonstrate this approach with data from a short telephone-administered neuropsychological battery given to a large, neurologically healthy sample aged 45-85 years old. We explored whether adjustments for age and medical conditions were warranted based on differential base rates of spuriously impaired scores. Theoretical base rates underestimated the frequency of impaired scores in older adults and overestimated the frequency of impaired scores in younger adults, providing an evidence base for the creation of age-corrected normative data. In contrast, the number of medical conditions (numerous cardiovascular, hormonal, and metabolic conditions) was not related to differential base rates of impaired scores. Despite a small correlation between number of medical conditions and each neuropsychological variable, normative adjustments for number of medical conditions does not appear warranted. Implications for creation of normative data are discussed.

Creating a three level building classification using topographic and address-based data for Manchester

NASA Astrophysics Data System (ADS)

Hussain, M.; Chen, D.

2014-11-01

Buildings, the basic unit of an urban landscape, host most of its socio-economic activities and play an important role in the creation of urban land-use patterns. The spatial arrangement of different building types creates varied urban land-use clusters which can provide an insight to understand the relationships between social, economic, and living spaces. The classification of such urban clusters can help in policy-making and resource management. In many countries including the UK no national-level cadastral database containing information on individual building types exists in public domain. In this paper, we present a framework for inferring functional types of buildings based on the analysis of their form (e.g. geometrical properties, such as area and perimeter, layout) and spatial relationship from large topographic and address-based GIS database. Machine learning algorithms along with exploratory spatial analysis techniques are used to create the classification rules. The classification is extended to two further levels based on the functions (use) of buildings derived from address-based data. The developed methodology was applied to the Manchester metropolitan area using the Ordnance Survey's MasterMap®, a large-scale topographic and address-based data available for the UK.

The role of solitons in charge and energy transfer in 1D molecular chains

NASA Astrophysics Data System (ADS)

Ivić , Zoran

1998-03-01

The idea that polarons and solitons could play the crucial role in the transport processes in biological structures, has been critically reexamined on the basis of the general theory of self-trapping phenomena. The criteria which enable one to determine conditions for the existence and stability of polarons and solitons and to determine their character, in dependence of the values of the basic physical parameters of the system, were formulated. Validity of the so-called Davydov's soliton model was discussed on the basis of these criteria. It was found that the original Davydov's proposal, based upon the idea of the soliton creation due to the single excitation (particle, vibron, etc.) self-trapping, cannot explain the intramolecular energy transfer in α-helix and acetanilide. However, Davydov theory is flexible enough to describe the single electron transfer in some systems (α-helix and acetanilide for example). In the many-particle systems, dressing effect, due to the quantum nature of phonons, may cause the creation of the bound states of the several excitons in the molecular chain. The possibility of creation of the soliton states of this type is discussed for the simple Fröhlich's one-dimensional model. The regions of the system parameter space where different mechanisms dominate the behaviour of such entities are characterized.

The MovieClassroom: An Internet Based Application for Students and Instructors to Create Captioned Animations.

NASA Astrophysics Data System (ADS)

Urbano, L.

2005-12-01

We have developed and tested an internet based application that facilitates the creation of animations for use in lectures and permits movie production by students in laboratory classes. Animation have been found to be extremely useful educational aids in the geosciences, particularly relating to topics requiring comprehension of geospatial relationships. With this program, instructors are able to assemble and caption animations using an online video clip catalogue and present these movies through a standard internet browser. Captioning increases student comprehension by increasing the multimodality of information delivery. For student use, we developed an exercise for introductory, undergraduate, laboratory class sections that was informed by learning pedagogy, particularly as related to game-based learning. Students were asked to assemble video clips and captions into a coherent movie to explain geospatial concepts, with questions such as "Explain why we have seasons?" The affinity of students to digital technology, particularly computer games and digital media, makes this type of exercise particularly captivating to the typical undergraduate. The opportunity to select and arrange video clips (and add background music) into a unique production offers students a greater degree of ownership of the learning process and allows unique non-linear pathways for accomplishing learning objectives. Use in a laboratory section permitted rapid feedback from the instructor. The application was created using open-sourced software and the database populated with video clips and music contributed by faculty and students under a non-commercial-use license. This tool has the potential to permit the wider dissemination of scientific research results given the increasing use animations for scientific visualization, because it eases the creation of multiple presentations targeted to various audiences and allows user participation in the creation of multimedia.

Venture Creation Programs: Bridging Entrepreneurship Education and Technology Transfer

ERIC Educational Resources Information Center

Lackéus, Martin; Williams Middleton, Karen

2015-01-01

Purpose: The purpose of this paper is to explore how university-based entrepreneurship programs, incorporating real-life venture creation into educational design and delivery, can bridge the gap between entrepreneurship education and technology transfer within the university environment. Design/methodology/approach: Based on a literature review…

Accountability for Project-Based Collaborative Learning

ERIC Educational Resources Information Center

Jamal, Abu-Hussain; Essawi, Mohammad; Tilchin, Oleg

2014-01-01

One perspective model for the creation of the learning environment and engendering students' thinking development is the Project-Based Collaborative Learning (PBCL) model. This model organizes learning by collaborative performance of various projects. In this paper we describe an approach to enhancing the PBCL model through the creation of…

36 CFR 1222.12 - What types of documentary materials are Federal records?

Code of Federal Regulations, 2010 CFR

2010-07-01

... 36 Parks, Forests, and Public Property 3 2010-07-01 2010-07-01 false What types of documentary... AND RECORDS ADMINISTRATION RECORDS MANAGEMENT CREATION AND MAINTENANCE OF FEDERAL RECORDS Identifying Federal Records § 1222.12 What types of documentary materials are Federal records? (a) General. To ensure...

Gravitationally influenced particle creation models and late-time cosmic acceleration

NASA Astrophysics Data System (ADS)

Pan, Supriya; Kumar Pal, Barun; Pramanik, Souvik

In this work, we focus on the gravitationally influenced adiabatic particle creation process, a mechanism that does not need any dark energy or modified gravity models to explain the current accelerating phase of the universe. Introducing some particle creation models that generalize some previous models in the literature, we constrain the cosmological scenarios using the latest compilation of the Type Ia Supernovae data only, the first indicator of the accelerating universe. Aside from the observational constraints on the models, we examine the models using two model independent diagnoses, namely the cosmography and Om. Further, we establish the general conditions to test the thermodynamic viabilities of any particle creation model. Our analysis shows that at late-time, the models have close resemblance to that of the ΛCDM cosmology, and the models always satisfy the generalized second law of thermodynamics under certain conditions.

Fiber-optic fluorescence imaging

PubMed Central

Flusberg, Benjamin A; Cocker, Eric D; Piyawattanametha, Wibool; Jung, Juergen C; Cheung, Eunice L M; Schnitzer, Mark J

2010-01-01

Optical fibers guide light between separate locations and enable new types of fluorescence imaging. Fiber-optic fluorescence imaging systems include portable handheld microscopes, flexible endoscopes well suited for imaging within hollow tissue cavities and microendoscopes that allow minimally invasive high-resolution imaging deep within tissue. A challenge in the creation of such devices is the design and integration of miniaturized optical and mechanical components. Until recently, fiber-based fluorescence imaging was mainly limited to epifluorescence and scanning confocal modalities. Two new classes of photonic crystal fiber facilitate ultrashort pulse delivery for fiber-optic two-photon fluorescence imaging. An upcoming generation of fluorescence imaging devices will be based on microfabricated device components. PMID:16299479

Achieving Research Impact Through Co‐creation in Community‐Based Health Services: Literature Review and Case Study

PubMed Central

JACKSON, CLAIRE; SHAW, SARA; JANAMIAN, TINA

2016-01-01

Policy Points: Co‐creation—collaborative knowledge generation by academics working alongside other stakeholders—is an increasingly popular approach to aligning research and service development.It has potential for “moving beyond the ivory towers” to deliver significant societal impact via dynamic, locally adaptive community‐academic partnerships.Principles of successful co‐creation include a systems perspective, a creative approach to research focused on improving human experience, and careful attention to governance and process.If these principles are not followed, co‐creation efforts may fail. Context Co‐creation—collaborative knowledge generation by academics working alongside other stakeholders—reflects a “Mode 2” relationship (knowledge production rather than knowledge translation) between universities and society. Co‐creation is widely believed to increase research impact. Methods We undertook a narrative review of different models of co‐creation relevant to community‐based health services. We contrasted their diverse disciplinary roots and highlighted their common philosophical assumptions, principles of success, and explanations for failures. We applied these to an empirical case study of a community‐based research‐service partnership led by the Centre of Research Excellence in Quality and Safety in Integrated Primary‐Secondary Care at the University of Queensland, Australia. Findings Co‐creation emerged independently in several fields, including business studies (“value co‐creation”), design science (“experience‐based co‐design”), computer science (“technology co‐design”), and community development (“participatory research”). These diverse models share some common features, which were also evident in the case study. Key success principles included (1) a systems perspective (assuming emergence, local adaptation, and nonlinearity); (2) the framing of research as a creative enterprise with human experience at its core; and (3) an emphasis on process (the framing of the program, the nature of relationships, and governance and facilitation arrangements, especially the style of leadership and how conflict is managed). In both the literature review and the case study, co‐creation “failures” could often be tracked back to abandoning (or never adopting) these principles. All co‐creation models made strong claims for significant and sustainable societal impacts as a result of the adaptive and developmental research process; these were illustrated in the case study. Conclusions Co‐creation models have high potential for societal impact but depend critically on key success principles. To capture the nonlinear chains of causation in the co‐creation pathway, impact metrics must reflect the dynamic nature and complex interdependencies of health research systems and address processes as well as outcomes. PMID:27265562

FacetModeller: Software for manual creation, manipulation and analysis of 3D surface-based models

NASA Astrophysics Data System (ADS)

Lelièvre, Peter G.; Carter-McAuslan, Angela E.; Dunham, Michael W.; Jones, Drew J.; Nalepa, Mariella; Squires, Chelsea L.; Tycholiz, Cassandra J.; Vallée, Marc A.; Farquharson, Colin G.

2018-01-01

The creation of 3D models is commonplace in many disciplines. Models are often built from a collection of tessellated surfaces. To apply numerical methods to such models it is often necessary to generate a mesh of space-filling elements that conforms to the model surfaces. While there are meshing algorithms that can do so, they place restrictive requirements on the surface-based models that are rarely met by existing 3D model building software. Hence, we have developed a Java application named FacetModeller, designed for efficient manual creation, modification and analysis of 3D surface-based models destined for use in numerical modelling.

Views of Community Managers on Knowledge Co-creation in Online Communities for People With Disabilities: Qualitative Study

PubMed Central

Rubinelli, Sara

2017-01-01

Background The use of online communities to promote end user involvement and co-creation in the product and service innovation process is well documented in the marketing and management literature. Whereas online communities are widely used for health care service provision and peer-to-peer support, only little is known about how they could be integrated into the health care innovation process. Objective The overall objective of this qualitative study was to explore community managers’ views on and experiences with knowledge co-creation in online communities for people with disabilities. Methods A descriptive qualitative research design was used. Data were collected through semi-structured interviews with nine community managers. To complement the interview data, additional information was retrieved from the communities in the form of structural information (number of registered users, number and names of topic areas covered by the forum) and administrative information (terms and conditions and privacy statements, forum rules). Data were analyzed using thematic analysis. Results Our results highlight two main aspects: peer-to-peer knowledge co-creation and types of collaboration with external actors. Although community managers strongly encouraged peer-to-peer knowledge co-creation, our findings indicated that these activities were not common practice in the communities under investigation. In fact, much of what related to co-creation, prototyping, and product development was still perceived to be directed by professionals and experts. Community managers described the role of their respective communities as informing this process rather than a driving force. The role of community members as advisors to researchers, health care professionals, and businesses was discussed in the context of types of collaboration with external actors. According to the community managers, most of the external inquiries related to research projects of students or health care professionals in training, who often joined a community for the sole purpose of recruiting participants for their research. Despite this unilateral form of knowledge co-creation, community managers acknowledged the mere interest of these user groups as beneficial, as long as their interest was not purely financially motivated. Being able to contribute to advancing research, improving products, and informing the planning and design of health care services were described as some of the key motivations to engage with external stakeholders. Conclusions This paper draws attention to the currently under-investigated role of online communities as platforms for collaboration and co-creation between patients, health care professionals, researchers, and businesses. It describes community managers’ views on and experiences with knowledge co-creation and provides recommendations on how these activities can be leveraged to foster knowledge co-creation in health care. Engaging in knowledge co-creation with online health communities may ultimately help to inform the planning and design of products, services, and research activities that better meet the actual needs of those living with a disability. PMID:29017993

Views of Community Managers on Knowledge Co-creation in Online Communities for People With Disabilities: Qualitative Study.

PubMed

Amann, Julia; Rubinelli, Sara

2017-10-10

The use of online communities to promote end user involvement and co-creation in the product and service innovation process is well documented in the marketing and management literature. Whereas online communities are widely used for health care service provision and peer-to-peer support, only little is known about how they could be integrated into the health care innovation process. The overall objective of this qualitative study was to explore community managers' views on and experiences with knowledge co-creation in online communities for people with disabilities. A descriptive qualitative research design was used. Data were collected through semi-structured interviews with nine community managers. To complement the interview data, additional information was retrieved from the communities in the form of structural information (number of registered users, number and names of topic areas covered by the forum) and administrative information (terms and conditions and privacy statements, forum rules). Data were analyzed using thematic analysis. Our results highlight two main aspects: peer-to-peer knowledge co-creation and types of collaboration with external actors. Although community managers strongly encouraged peer-to-peer knowledge co-creation, our findings indicated that these activities were not common practice in the communities under investigation. In fact, much of what related to co-creation, prototyping, and product development was still perceived to be directed by professionals and experts. Community managers described the role of their respective communities as informing this process rather than a driving force. The role of community members as advisors to researchers, health care professionals, and businesses was discussed in the context of types of collaboration with external actors. According to the community managers, most of the external inquiries related to research projects of students or health care professionals in training, who often joined a community for the sole purpose of recruiting participants for their research. Despite this unilateral form of knowledge co-creation, community managers acknowledged the mere interest of these user groups as beneficial, as long as their interest was not purely financially motivated. Being able to contribute to advancing research, improving products, and informing the planning and design of health care services were described as some of the key motivations to engage with external stakeholders. This paper draws attention to the currently under-investigated role of online communities as platforms for collaboration and co-creation between patients, health care professionals, researchers, and businesses. It describes community managers' views on and experiences with knowledge co-creation and provides recommendations on how these activities can be leveraged to foster knowledge co-creation in health care. Engaging in knowledge co-creation with online health communities may ultimately help to inform the planning and design of products, services, and research activities that better meet the actual needs of those living with a disability. ©Julia Amann, Sara Rubinelli. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 10.10.2017.

Direct detection of light dark matter and solar neutrinos via color center production in crystals

NASA Astrophysics Data System (ADS)

Budnik, Ranny; Cheshnovsky, Ori; Slone, Oren; Volansky, Tomer

2018-07-01

We propose a new low-threshold direct-detection concept for dark matter and for coherent nuclear scattering of solar neutrinos, based on the dissociation of atoms and subsequent creation of color center type defects within a lattice. The novelty in our approach lies in its ability to detect single defects in a macroscopic bulk of material. This class of experiments features ultra-low energy thresholds which allows for the probing of dark matter as light as O (10) MeV through nuclear scattering. Another feature of defect creation in crystals is directional information, which presents as a spectacular signal and a handle on background reduction in the form of daily modulation of the interaction rate. We discuss the envisioned setup and detection technique, as well as background reduction. We further calculate the expected rates for dark matter and solar neutrinos in two example crystals for which available data exists, demonstrating the prospective sensitivity of such experiments.

Alexander Meets Michotte: A Simulation Tool Based on Pattern Programming and Phenomenology

ERIC Educational Resources Information Center

Basawapatna, Ashok

2016-01-01

Simulation and modeling activities, a key point of computational thinking, are currently not being integrated into the science classroom. This paper describes a new visual programming tool entitled the Simulation Creation Toolkit. The Simulation Creation Toolkit is a high level pattern-based phenomenological approach to bringing rapid simulation…

Vascular Access Creation before Hemodialysis Initiation and Use: A Population-Based Cohort Study

PubMed Central

Al-Jaishi, Ahmed A.; Lok, Charmaine E.; Garg, Amit X.; Zhang, Joyce C.

2015-01-01

Background and objectives In Canada, approximately 17% of patients use an arteriovenous access (fistula or arteriovenous graft) at commencement of hemodialysis, despite guideline recommendations promoting its timely creation and use. It is unclear if this low pattern of use is attributable to the lack of surgical creation or a high nonuse rate. Design, setting, participants, & measurements Using large health care databases in Ontario, Canada, a population-based cohort of adult patients (≥18 years old) who initiated hemodialysis as their first form of RRT between 2001 and 2010 was studied. The aims were to (1) estimate the proportion of patients who had an arteriovenous access created before starting hemodialysis and the proportion who successfully used it at hemodialysis start, (2) test for secular trends in arteriovenous access creation, and (3) estimate the effect of late nephrology referral and patient characteristics on arteriovenous access creation. Results There were 17,183 patients on incident hemodialysis. The mean age was 65.8 years, 60% were men, and 40% were referred late to a nephrologist; 27% of patients (4556 of 17,183) had one or more arteriovenous accesses created, and the median time between arteriovenous access creation and hemodialysis start was 184 days. When late referrals were excluded, 39% of patients (4007 of 10,291) had one or more arteriovenous accesses created, and 27% of patients (2724 of 10,291) used the arteriovenous access. Since 2001, there has been a decline in arteriovenous access creation before hemodialysis initiation. Women, higher numbers of comorbidities, and rural residence were consistently associated with lower rates of arteriovenous access creation. These results persisted even after removing patients with <6 months nephrology care or who had AKI 6 months before starting hemodialysis. Conclusions In Canada, arteriovenous access creation before hemodialysis initiation is low, even among patients followed by a nephrologist. Better understanding of the barriers and influencers of arteriovenous access creation is needed to inform both clinical care and guidelines. PMID:25568219

Vascular access creation before hemodialysis initiation and use: a population-based cohort study.

PubMed

Al-Jaishi, Ahmed A; Lok, Charmaine E; Garg, Amit X; Zhang, Joyce C; Moist, Louise M

2015-03-06

In Canada, approximately 17% of patients use an arteriovenous access (fistula or arteriovenous graft) at commencement of hemodialysis, despite guideline recommendations promoting its timely creation and use. It is unclear if this low pattern of use is attributable to the lack of surgical creation or a high nonuse rate. Using large health care databases in Ontario, Canada, a population-based cohort of adult patients (≥18 years old) who initiated hemodialysis as their first form of RRT between 2001 and 2010 was studied. The aims were to (1) estimate the proportion of patients who had an arteriovenous access created before starting hemodialysis and the proportion who successfully used it at hemodialysis start, (2) test for secular trends in arteriovenous access creation, and (3) estimate the effect of late nephrology referral and patient characteristics on arteriovenous access creation. There were 17,183 patients on incident hemodialysis. The mean age was 65.8 years, 60% were men, and 40% were referred late to a nephrologist; 27% of patients (4556 of 17,183) had one or more arteriovenous accesses created, and the median time between arteriovenous access creation and hemodialysis start was 184 days. When late referrals were excluded, 39% of patients (4007 of 10,291) had one or more arteriovenous accesses created, and 27% of patients (2724 of 10,291) used the arteriovenous access. Since 2001, there has been a decline in arteriovenous access creation before hemodialysis initiation. Women, higher numbers of comorbidities, and rural residence were consistently associated with lower rates of arteriovenous access creation. These results persisted even after removing patients with <6 months nephrology care or who had AKI 6 months before starting hemodialysis. In Canada, arteriovenous access creation before hemodialysis initiation is low, even among patients followed by a nephrologist. Better understanding of the barriers and influencers of arteriovenous access creation is needed to inform both clinical care and guidelines. Copyright © 2015 by the American Society of Nephrology.

'Ethos' Enabling Organisational Knowledge Creation

NASA Astrophysics Data System (ADS)

Matsudaira, Yoshito

This paper examines knowledge creation in relation to improvements on the production line in the manufacturing department of Nissan Motor Company and aims to clarify embodied knowledge observed in the actions of organisational members who enable knowledge creation will be clarified. For that purpose, this study adopts an approach that adds a first, second, and third-person's viewpoint to the theory of knowledge creation. Embodied knowledge, observed in the actions of organisational members who enable knowledge creation, is the continued practice of 'ethos' (in Greek) founded in Nissan Production Way as an ethical basis. Ethos is knowledge (intangible) assets for knowledge creating companies. Substantiated analysis classifies ethos into three categories: the individual, team and organisation. This indicates the precise actions of the organisational members in each category during the knowledge creation process. This research will be successful in its role of showing the indispensability of ethos - the new concept of knowledge assets, which enables knowledge creation -for future knowledge-based management in the knowledge society.

VHDL-AMS modelling and simulation of a planar electrostatic micromotor

NASA Astrophysics Data System (ADS)

Endemaño, A.; Fourniols, J. Y.; Camon, H.; Marchese, A.; Muratet, S.; Bony, F.; Dunnigan, M.; Desmulliez, M. P. Y.; Overton, G.

2003-09-01

System level simulation results of a planar electrostatic micromotor, based on analytical models of the static and dynamic torque behaviours, are presented. A planar variable capacitance (VC) electrostatic micromotor designed, fabricated and tested at LAAS (Toulouse) in 1995 is simulated using the high level language VHDL-AMS (VHSIC (very high speed integrated circuits) hardware description language-analog mixed signal). The analytical torque model is obtained by first calculating the overlaps and capacitances between different electrodes based on a conformal mapping transformation. Capacitance values in the order of 10-16 F and torque values in the order of 10-11 N m have been calculated in agreement with previous measurements and simulations from this type of motor. A dynamic model has been developed for the motor by calculating the inertia coefficient and estimating the friction-coefficient-based values calculated previously for other similar devices. Starting voltage results obtained from experimental measurement are in good agreement with our proposed simulation model. Simulation results of starting voltage values, step response, switching response and continuous operation of the micromotor, based on the dynamic model of the torque, are also presented. Four VHDL-AMS blocks were created, validated and simulated for power supply, excitation control, micromotor torque creation and micromotor dynamics. These blocks can be considered as the initial phase towards the creation of intellectual property (IP) blocks for microsystems in general and electrostatic micromotors in particular.

Understanding innovation in social service delivery systems.

PubMed

Moore, S

1994-01-01

Progress in the social services is driven by innovation. It depends on the ability of social work researchers and practitioners to find innovative solutions to the problems they face. Innovation entails the creation, adaptation, and adoption of new approaches to service delivery. The most fundamental type of innovation is the creation of a new service product. However, innovations in the way services are delivered are equally important. This paper provides a model for understanding innovation in social services.

Case-based synthesis in automatic advertising creation system

NASA Astrophysics Data System (ADS)

Zhuang, Yueting; Pan, Yunhe

1995-08-01

Advertising (ads) is an important design area. Though many interactive ad-design softwares have come into commercial use, none of them ever support the intelligent work -- automatic ad creation. The potential for this is enormous. This paper gives a description of our current work in research of an automatic advertising creation system (AACS). After careful analysis of the mental behavior of a human ad designer, we conclude that case-based approach is appropriate to its intelligent modeling. A model for AACS is given in the paper. A case in ads is described as two parts: the creation process and the configuration of the ads picture, with detailed data structures given in the paper. Along with the case representation, we put forward an algorithm. Some issues such as similarity measure computing, and case adaptation have also been discussed.

Modeling in architectural-planning solutions of agrarian technoparks as elements of the infrastructure

NASA Astrophysics Data System (ADS)

Abdrassilova, Gulnara S.

2017-09-01

In the context of development of the agriculture as the driver of the economy of Kazakhstan it is imperative to study new types of agrarian constructions (agroparks, agrotourists complexes, "vertical" farms, conservatories, greenhouses) that can be combined into complexes - agrarian technoparks. Creation of agrarian technoparks as elements of the infrastructure of the agglomeration shall ensure the breakthrough in the field of agrarian goods production, storing and recycling. Modeling of architectural-planning solutions of agrarian technoparks supports development of the theory and practice of designing objects based on innovative approaches.

Complication Rates of Ostomy Surgery Are High and Vary Significantly Between Hospitals

PubMed Central

Sheetz, Kyle H.; Waits, Seth A.; Krell, Robert W.; Morris, Arden M.; Englesbe, Michael J.; Mullard, Andrew; Campbell, Darrell A.; Hendren, Samantha

2014-01-01

Structured Abstract Background Ostomy surgery is common and has traditionally been associated with high rates of morbidity and mortality, suggesting an important target for quality improvement. Objective To evaluate the variation in outcomes after ostomy creation surgery within Michigan in order to identify targets for quality improvement. Design Retrospective cohort study. Setting The 34-hospital Michigan Surgical Quality Collaborative (MSQC). Patients Patients undergoing ostomy creation surgery between 2006-2011. Main outcome measures We evaluated hospitals' morbidity and mortality rates after risk-adjustment (age, comorbidities, emergency v. elective, procedure type). Results 4,250 patients underwent ostomy creation surgery; 3,866 (91.0%) procedures were open and 384 (9.0%) were laparoscopic. Unadjusted morbidity and mortality rates were 43.9% and 10.7%, respectively. Unadjusted morbidity rates for specific procedures ranged from 32.7% for ostomy-creation-only procedures to 47.8% for Hartmann's procedures. Risk-adjusted morbidity rates varied significantly between hospitals, ranging from 31.2% (95%CI 18.4-43.9) to 60.8% (95%CI 48.9-72.6). There were five statistically-significant high-outlier hospitals and three statistically-significant low-outlier hospitals for risk-adjusted morbidity. The pattern of complication types was similar between high- and low-outlier hospitals. Case volume, operative duration, and use of laparoscopic surgery did not explain the variation in morbidity rates across hospitals. Conclusions Morbidity and mortality rates for modern ostomy surgery are high. While this type of surgery has received little attention in healthcare policy, these data reveal that it is both common and uncommonly morbid. Variation in hospital performance provides an opportunity to identify quality improvement practices that could be disseminated among hospitals. PMID:24819104

Transgenic mice: an irreplaceable tool for the study of mammalian development and biology.

PubMed

Babinet, C

2000-11-01

Stable integration into the mouse genome of exogenous genetic information, i.e., the creation of transgenic mice, has become a privileged way of analyzing gene function in normal development and pathology. Both gene addition and gene replacement may be performed. This has allowed, in particular, the creation of mice in which precise mutations are introduced into a given gene. Furthermore, in recent years, strategies that induce the expression of a mutation in a given type of cell and/or at a given time in development have been developed. Thus, the transgenic methodology affords a unique and irreplaceable tool for the study of mammalian development and biology and for the creation of animal models for human genetic diseases.

The creation of virtual teeth with and without tooth pathology for a virtual learning environment in dental education.

PubMed

de Boer, I R; Wesselink, P R; Vervoorn, J M

2013-11-01

To describe the development and opportunities for implementation of virtual teeth with and without pathology for use in a virtual learning environment in dental education. The creation of virtual teeth begins by scanning a tooth with a cone beam CT. The resulting scan consists of multiple two-dimensional grey-scale images. The specially designed software program ColorMapEditor connects these two-dimensional images to create a three-dimensional tooth. With this software, any aspect of the tooth can be modified, including its colour, volume, shape and density, resulting in the creation of virtual teeth of any type. This article provides examples of realistic virtual teeth with and without pathology that can be used for dental education. ColorMapEditor offers infinite possibilities to adjust and add options for the optimisation of virtual teeth. Virtual teeth have unlimited availability for dental students, allowing them to practise as often as required. Virtual teeth can be made and adjusted to any shape with any type of pathology. Further developments in software and hardware technology are necessary to refine the ability to colour and shape the interior of the pulp chamber and surface of the tooth to enable not only treatment but also diagnostics and thus create a greater degree of realism. The creation and use of virtual teeth in dental education appears to be feasible but is still in development; it offers many opportunities for the creation of teeth with various pathologies, although an evaluation of its use in dental education is still required. © 2013 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Charting Collective Knowledge: Supporting Self-Regulated Learning in the Workplace

ERIC Educational Resources Information Center

Littlejohn, Allison; Milligan, Colin; Margaryan, Anoush

2012-01-01

Purpose: This study aims to outline an approach to improving the effectiveness of work-based learning through knowledge creation and enhancing self-regulated learning. The paper presents a case example of a novel approach to learning through knowledge creation in the workplace. This case example is based on empirical data collected through a study…

Redesigning Problem-Based Learning in the Knowledge Creation Paradigm for School Science Learning

ERIC Educational Resources Information Center

Yeo, Jennifer; Tan, Seng Chee

2014-01-01

The introduction of problem-based learning into K-12 science classrooms faces the challenge of achieving the dual goal of learning science content and developing problem-solving skills. To overcome this content-process tension in science classrooms, we employed the knowledge-creation approach as a boundary object between the two seemingly…

Science-On Line: Partnership Approach for the Creation of Internet-based Classroom Resources.

ERIC Educational Resources Information Center

Hawkins, Isabel; Battle, Robyn

Research has been conducted which develops case studies on how to engage scientists in partnerships with teachers. Studies have focused on the Internet and the World Wide Web as potential conduits of research results to the classroom, particularly if scientists and teachers were involved in joint creation of Internet-based curriculum and lesson…

Using a Co-Creational Approach to Develop, Implement and Evaluate an Intervention to Promote Physical Activity in Adolescent Girls from Vocational and Technical Schools: A Case Control Study

PubMed Central

Verloigne, Maïté; Altenburg, Teatske Maria; Chinapaw, Mai Jeanette Maidy; Chastin, Sebastien; Cardon, Greet

2017-01-01

Background: As physical inactivity is particularly prevalent amongst lower-educated adolescent girls, interventions are needed. Using a co-creational approach increases their engagement and might be effective. This study aimed to: (1) describe the co-creation process, (2) evaluate how girls experienced co-creation, and (3) evaluate the effect of the co-creational interventions on physical activity, individual, sociocultural and school-based factors. Methods: Three intervention schools (n = 91) and three control schools (n = 105) across Flanders participated. A questionnaire was completed pre (September–October 2014) and post (April–May 2015). In between, sessions with a co-creation group were organised to develop and implement the intervention in each intervention school. Focus groups were conducted to evaluate the co-creational process. Results: School 1 organised sport sessions for girls, school 2 organised a fitness activity and set up a Facebook page, school 3 organised a lunch walk. Girls were positive about having a voice in developing an intervention. No significant effects were found, except for small effects on extracurricular sports participation and self-efficacy. Conclusions: Using a co-creational approach amongst adolescent girls might be a feasible approach. However, as interventions were minimal, effects were limited or undetectable. Future co-creation projects could consider the most optimal co-creation process, evaluation design and intensively test this approach. PMID:28763041

Using a Co-Creational Approach to Develop, Implement and Evaluate an Intervention to Promote Physical Activity in Adolescent Girls from Vocational and Technical Schools: A Case Control Study.

PubMed

Verloigne, Maïté; Altenburg, Teatske Maria; Chinapaw, Mai Jeanette Maidy; Chastin, Sebastien; Cardon, Greet; De Bourdeaudhuij, Ilse

2017-08-01

Background: As physical inactivity is particularly prevalent amongst lower-educated adolescent girls, interventions are needed. Using a co-creational approach increases their engagement and might be effective. This study aimed to: (1) describe the co-creation process, (2) evaluate how girls experienced co-creation, and (3) evaluate the effect of the co-creational interventions on physical activity, individual, sociocultural and school-based factors. Methods: Three intervention schools (n = 91) and three control schools (n = 105) across Flanders participated. A questionnaire was completed pre (September-October 2014) and post (April-May 2015). In between, sessions with a co-creation group were organised to develop and implement the intervention in each intervention school. Focus groups were conducted to evaluate the co-creational process. Results: School 1 organised sport sessions for girls, school 2 organised a fitness activity and set up a Facebook page, school 3 organised a lunch walk. Girls were positive about having a voice in developing an intervention. No significant effects were found, except for small effects on extracurricular sports participation and self-efficacy. Conclusions: Using a co-creational approach amongst adolescent girls might be a feasible approach. However, as interventions were minimal, effects were limited or undetectable. Future co-creation projects could consider the most optimal co-creation process, evaluation design and intensively test this approach.

"Musical co-creation"? Exploring health-promoting potentials on the use of musical and interactive tangibles for families with children with disabilities.

PubMed

Stensæth, Karette

2013-08-07

The point of departure in this text is the ongoing qualitative interdisciplinary research project RHYME (www.RHYME.no), which addresses the lack of health-promoting interactive and musical Information and Communications Technology (ICT) for families with children with severe disabilities. The project explores a new treatment paradigm based on collaborative, tangible, interactive net-based musical "smart things" with multimedia capabilities. The goal in RHYME is twofold: (1) to reduce isolation and passivity, and (2) to promote health and well-being. Co-creation is suggested as a possible path to achieving these goals, by evoking feelings, for example, or accommodating the needs to act and to create social relations; co-creation also motivates users to communicate and collaborate within (new) social relations. This article engages co-creation by incorporating aspects connected to interaction design and the field of music and health. Empirical observations will be referred to. The research question is as follows: What might co-creation imply for families of children with disabilities when musical and interactive tangibles are used as health-promoting implements?

Some design constraints required for the assembly of software components: The incorporation of atomic abstract types into generically structured abstract types

NASA Technical Reports Server (NTRS)

Johnson, Charles S.

1986-01-01

It is nearly axiomatic, that to take the greatest advantage of the useful features available in a development system, and to avoid the negative interactions of those features, requires the exercise of a design methodology which constrains their use. A major design support feature of the Ada language is abstraction: for data, functions processes, resources, and system elements in general. Atomic abstract types can be created in packages defining those private types and all of the overloaded operators, functions, and hidden data required for their use in an application. Generically structured abstract types can be created in generic packages defining those structured private types, as buildups from the user-defined data types which are input as parameters. A study is made of the design constraints required for software incorporating either atomic or generically structured abstract types, if the integration of software components based on them is to be subsequently performed. The impact of these techniques on the reusability of software and the creation of project-specific software support environments is also discussed.

TEQUEL: The query language of SADDLE

NASA Technical Reports Server (NTRS)

Rajan, S. D.

1984-01-01

A relational database management system is presented that is tailored for engineering applications. A wide variety of engineering data types are supported and the data definition language (DDL) and data manipulation language (DML) are extended to handle matrices. The system can be used either in the standalone mode or through a FORTRAN or PASCAL application program. The query language is of the relational calculus type and allows the user to store, retrieve, update and delete tuples from relations. The relational operations including union, intersect and differ facilitate creation of temporary relations that can be used for manipulating information in a powerful manner. Sample applications are shown to illustrate the creation of data through a FORTRAN program and data manipulation using the TEQUEL DML.

Bubbling route to strange nonchaotic attractor in a nonlinear series LCR circuit with a nonsinusoidal force.

PubMed

Senthilkumar, D V; Srinivasan, K; Thamilmaran, K; Lakshmanan, M

2008-12-01

We identify an unconventional route to the creation of a strange nonchaotic attractor (SNA) in a quasiperiodically forced electronic circuit with a nonsinusoidal (square wave) force as one of the quasiperiodic forces through numerical and experimental studies. We find that bubbles appear in the strands of the quasiperiodic attractor due to the instability induced by the additional square-wave-type force. The bubbles then enlarge and get increasingly wrinkled as a function of the control parameter. Finally, the bubbles get extremely wrinkled (while the remaining parts of the strands of the torus remain largely unaffected) resulting in the creation of the SNA; we term this the bubbling route to the SNA. We characterize and confirm this creation from both experimental and numerical data using maximal Lyapunov exponents and their variance, Poincaré maps, Fourier amplitude spectra, and spectral distribution functions. We also strongly confirm the creation of a SNA via the bubbling route by the distribution of the finite-time Lyapunov exponents.

Tactical Network Load Balancing in Multi-Gateway Wireless Sensor Networks

DTIC Science & Technology

2013-12-01

writeup scrsz = get( 0 ,’ScreenSize’); %Creation of the random Sensor Network fig = figure(1); set(fig, ’Position’,[1 scrsz( 4 )*.25 scrsz(3)*.7...thesis writeup scrsz = get( 0 ,’ScreenSize’); %Creation of the random Sensor Network fig = figure(1); set(fig, ’Position’,[1 scrsz( 4 )*.25 scrsz(3)*.7...TYPE AND DATES COVERED Master’s Thesis 4 . TITLE AND SUBTITLE TACTICAL NETWORK LOAD BALANCING IN MULTI-GATEWAY WIRELESS SENSOR NETWORKS 5

Informational model verification of ZVS Buck quasi-resonant DC-DC converter

NASA Astrophysics Data System (ADS)

Vakovsky, Dimiter; Hinov, Nikolay

2016-12-01

The aim of the paper is to create a polymorphic informational model of a ZVS Buck quasi-resonant DC-DC converter for the modeling purposes of the object. For the creation of the model is applied flexible open standards for setting, storing, publishing and exchange of data in distributed information environment. The created model is useful for creation of many and different by type variants with different configuration of the composing elements and different inner model of the examined object.

Step-by-step fabrication of a highly oriented crystalline three-dimensional pillared-layer-type metal-organic framework thin film confirmed by synchrotron X-ray diffraction.

PubMed

Otsubo, Kazuya; Haraguchi, Tomoyuki; Sakata, Osami; Fujiwara, Akihiko; Kitagawa, Hiroshi

2012-06-13

Fabrication of a crystalline ordered thin film based on the porous metal-organic frameworks (MOFs) is one of the practical applications of the future functional nanomaterials. Here, we report the creation of a highly oriented three-dimensional (3-D) porous pillared-layer-type MOF thin film on a metal substrate using a step-by-step approach based on liquid-phase epitaxy. Synchrotron X-ray diffraction (XRD) study clearly indicates that the thin film is crystalline and its orientation is highly controlled in both horizontal and vertical directions relative to the substrate. This report provides the first confirmation of details of not only the crystallinity but also the orientation of 3-D MOF thin film using synchrotron XRD. Moreover, we also demonstrate its guest adsorption/desorption behavior by using in situ XRD measurements. The results presented here would promise useful insights for fabrication of MOF-based nanodevices in the future.

Patients started on hemodialysis with tunneled dialysis catheter have similar survival after arteriovenous fistula and arteriovenous graft creation.

PubMed

Yuo, Theodore H; Chaer, Rabih A; Dillavou, Ellen D; Leers, Steven A; Makaroun, Michel S

2015-12-01

Current guidelines suggest that arteriovenous fistula (AVF) is associated with survival advantage over arteriovenous graft (AVG). However, AVFs often require months to become functional, increasing tunneled dialysis catheter (TDC) use, which can erode the benefit of an AVF. We sought to compare survival in patients with end-stage renal disease after creation of an AVF or AVG in patients starting hemodialysis (HD) with a TDC and to identify patient populations that may benefit from preferential use of AVG over AVF. Using U.S. Renal Data System databases, we identified incident HD patients in 2005 through 2008 and observed them through 2008. Initial access type and clinical variables including albumin levels were assessed using U.S. Renal Data System data collection forms. Attempts at AVF and AVG creation in patients who started HD through a TDC were identified by Current Procedural Terminology codes. We accounted for the effect of changes in access type by truncating follow-up when an additional AVF or AVG was performed. Survival curves were then constructed, and log-rank tests were used for pairwise survival comparisons, stratified by age. Multivariate analysis was performed with Cox proportional hazards regressions; variables were chosen using stepwise elimination. An interaction of access type and albumin level was detected, and Cox models using differing thresholds for albumin level were constructed. The primary outcome was survival. Among the 138,245 patients who started with a TDC and had complete records amenable for analysis, 22.8% underwent AVF creation (mean age ± standard deviation, 68.9 ± 12.5 years; 27.8% mortality at 1 year) and 7.6% underwent AVG placement (70.2 ± 12.0 years; 28.2% mortality) within 3 months of HD initiation; 69.6% remained with a TDC (63.2 ± 15.4 years; 33.8% mortality). In adjusted Cox proportional hazards regression, AVF creation is equivalent to AVG placement in terms of survival (hazard ratio [HR], 0.98; 95% confidence interval [CI], 0.93-1.02; P = .349). AVG placement is superior to continued TDC use (HR, 1.54; 95% CI, 1.48-1.61; P < .001). In patients older than 80 years with albumin levels >4.0 g/dL, AVF creation is associated with higher mortality hazard compared with AVG creation (HR, 1.22; 95% CI, 1.04-1.43; P = .013). For patients who start HD through a TDC, placement of an AVF and AVG is associated with similar mortality hazard. Further study is necessary to determine the ideal access for patients in whom the survival advantage of an AVF over an AVG is uncertain. Copyright © 2015 Society for Vascular Surgery. Published by Elsevier Inc. All rights reserved.

NASA Interactive Forms Type Interface - NIFTI

NASA Technical Reports Server (NTRS)

Jain, Bobby; Morris, Bill

2005-01-01

A flexible database query, update, modify, and delete tool was developed that provides an easy interface to Oracle forms. This tool - the NASA interactive forms type interface, or NIFTI - features on-the- fly forms creation, forms sharing among users, the capability to query the database from user-entered criteria on forms, traversal of query results, an ability to generate tab-delimited reports, viewing and downloading of reports to the user s workstation, and a hypertext-based help system. NIFTI is a very powerful ad hoc query tool that was developed using C++, X-Windows by a Motif application framework. A unique tool, NIFTI s capabilities appear in no other known commercial-off-the- shelf (COTS) tool, because NIFTI, which can be launched from the user s desktop, is a simple yet very powerful tool with a highly intuitive, easy-to-use graphical user interface (GUI) that will expedite the creation of database query/update forms. NIFTI, therefore, can be used in NASA s International Space Station (ISS) as well as within government and industry - indeed by all users of the widely disseminated Oracle base. And it will provide significant cost savings in the areas of user training and scalability while advancing the art over current COTS browsers. No COTS browser performs all the functions NIFTI does, and NIFTI is easier to use. NIFTI s cost savings are very significant considering the very large database with which it is used and the large user community with varying data requirements it will support. Its ease of use means that personnel unfamiliar with databases (e.g., managers, supervisors, clerks, and others) can develop their own personal reports. For NASA, a tool such as NIFTI was needed to query, update, modify, and make deletions within the ISS vehicle master database (VMDB), a repository of engineering data that includes an indentured parts list and associated resource data (power, thermal, volume, weight, and the like). Since the VMDB is used both as a collection point for data and as a common repository for engineering, integration, and operations teams, a tool such as NIFTI had to be designed that could expedite the creation of database query/update forms which could then be shared among users.

Tools and Methods to Create Scenarios for Experimental Research in the Network Science Research Laboratory (NSRL)

DTIC Science & Technology

2015-12-01

research areas in network science. 15. SUBJECT TERMS scenario creation , emulation environment, NSRL 16. SECURITY CLASSIFICATION OF: 17. LIMITATION...mobility aspect of the emulated environment, the development and creation of scenarios play an integral part. By creating scenarios that model certain...during the visualization phase. We examine these 3 phases in detail by describing the creation of a scenario based upon a vignette from the Multi-Level

Co-production of knowledge: recipe for success in land-based climate change adaptation?

NASA Astrophysics Data System (ADS)

Coninx, Ingrid; Swart, Rob

2015-04-01

After multiple failures of scientists to trigger policymakers and other relevant actors to take action when communicating research findings, the request for co-production (or co-creation) of knowledge and stakeholder involvement in climate change adaptation efforts has rapidly increased over the past few years. In particular for land-based adaptation, on-the-ground action is often met by societal resistance towards solutions proposed by scientists, by a misfit of potential solutions with the local context, leading to misunderstanding and even rejection of scientific recommendations. A fully integrative co-creation process in which both scientists and practitioners discuss climate vulnerability and possible responses, exploring perspectives and designing adaptation measures based on their own knowledge, is expected to prevent the adaptation deadlock. The apparent conviction that co-creation processes result in successful adaptation, has not yet been unambiguously empirically demonstrated, but has resulted in co-creation being one of basic principles in many new research and policy programmes. But is co-creation that brings knowledge of scientists and practitioners together always the best recipe for success in climate change adaptation? Assessing a number of actual cases, the authors have serious doubts. The paper proposes additional considerations for adaptively managing the environment that should be taken into account in the design of participatory knowledge development in which climate scientists play a role. These include the nature of the problem at stake; the values, interests and perceptions of the actors involved; the methods used to build trust, strengthen alignment and develop reciprocal relationships among scientists and practitioners; and the concreteness of the co-creation output.

Facilitating 3D Virtual World Learning Environments Creation by Non-Technical End Users through Template-Based Virtual World Instantiation

ERIC Educational Resources Information Center

Liu, Chang; Zhong, Ying; Ozercan, Sertac; Zhu, Qing

2013-01-01

This paper presents a template-based solution to overcome technical barriers non-technical computer end users face when developing functional learning environments in three-dimensional virtual worlds (3DVW). "iVirtualWorld," a prototype of a platform-independent 3DVW creation tool that implements the proposed solution, facilitates 3DVW…

Creation of dialysis vascular access with normal flow increases brain natriuretic peptide levels.

PubMed

Malík, Jan; Tuka, Vladimir; Krupickova, Zdislava; Chytilova, Eva; Holaj, Robert; Slavikova, Marcela

2009-12-01

Chronic heart failure is very common in hemodialyzed patients due to several factors such as intermittent volume overload, anemia, and hypertension. Dialysis access flow is usually considered to have a minor effect. We hypothesized that creation of dialysis access with "normal" flow would lead to elevation of B-type natriuretic peptide (BNP), which is a sensitive marker of heart failure. We included subjects with a newly created, well-functioning vascular access and normal left ventricular ejection fraction. They were examined before access creation (baseline), then again 6 weeks and 6 months after the surgery. Only subjects with access flow (Qa) < 1500 ml/min were included. Changes of BNP levels and their relation to access flow were studied. We examined 35 subjects aged 60.6 +/- 13.5 years. Qa was 789 +/- 361 and 823 +/- 313 ml/min at 6 weeks and 6 months after the surgery, respectively. Within 6 weeks after access creation, BNP rose from 217 (294) to 267 (550) ng/l (median (quartile range)) with P = 0.003. Qa was significantly related to BNP levels 6 weeks after access creation (r = 0.37, P = 0.036). Six months after access creation, there was only a trend of BNP decrease (235 (308) ng/l, P = 0.44). Creatinine, blood urea nitrogen and hemoglobin levels as well as patients' weight did not change significantly. Creation of dialysis access with "normal" flow volume leads to significant increase of BNP, which is related to the value of access flow. The increase of BNP probably mirrors worsening of clinically silent heart failure.

36 CFR 1222.12 - What types of documentary materials are Federal records?

Code of Federal Regulations, 2011 CFR

2011-07-01

... 36 Parks, Forests, and Public Property 3 2011-07-01 2011-07-01 false What types of documentary materials are Federal records? 1222.12 Section 1222.12 Parks, Forests, and Public Property NATIONAL ARCHIVES AND RECORDS ADMINISTRATION RECORDS MANAGEMENT CREATION AND MAINTENANCE OF FEDERAL RECORDS Identifying...

36 CFR 1222.12 - What types of documentary materials are Federal records?

Code of Federal Regulations, 2014 CFR

2014-07-01

... 36 Parks, Forests, and Public Property 3 2014-07-01 2014-07-01 false What types of documentary materials are Federal records? 1222.12 Section 1222.12 Parks, Forests, and Public Property NATIONAL ARCHIVES AND RECORDS ADMINISTRATION RECORDS MANAGEMENT CREATION AND MAINTENANCE OF FEDERAL RECORDS Identifying...

36 CFR 1222.12 - What types of documentary materials are Federal records?

Code of Federal Regulations, 2012 CFR

2012-07-01

... 36 Parks, Forests, and Public Property 3 2012-07-01 2012-07-01 false What types of documentary materials are Federal records? 1222.12 Section 1222.12 Parks, Forests, and Public Property NATIONAL ARCHIVES AND RECORDS ADMINISTRATION RECORDS MANAGEMENT CREATION AND MAINTENANCE OF FEDERAL RECORDS Identifying...

Creation of a master table for checking indication and contraindication of medicine from a knowledge base linked with a thesaurus.

PubMed

Ji, Shanmei; Matsumura, Yasushi; Kuwata, Shigeki; Nakano, Hirohiko; Chen, Yufeng; Teratani, Tadamasa; Zhang, Qiyan; Mineno, Takahiro; Takeda, Hiroshi

2004-12-01

To develop a system for checking indication and contraindication of medicines in prescription order entry system, a master table consisting of the disease names corresponding to the medicines adopted in a hospital is needed. The creation of this table requires a considerable manpower. We developed a Web-based system for constructing a medicine/disease thesaurus and a knowledge base. By authority management of users, this system enables many specialists to create the thesaurus collaboratively without confusion. It supports the creation of a knowledge base using concept names by referring to the thesaurus, which is automatically converted to the check master table. When a disease name or medicine name was added to the thesaurus, the check table was automatically updated. We constructed a thesaurus and a knowledge base in the field of circulatory system disease. The knowledge base linked with the thesaurus proved to be efficient for making the check master table for indication/contraindication of medicines.

Network Analysis of an Emergent Massively Collaborative Creation on Video Sharing Website

NASA Astrophysics Data System (ADS)

Hamasaki, Masahiro; Takeda, Hideaki; Nishimura, Takuichi

The Web technology enables numerous people to collaborate in creation. We designate it as massively collaborative creation via the Web. As an example of massively collaborative creation, we particularly examine video development on Nico Nico Douga, which is a video sharing website that is popular in Japan. We specifically examine videos on Hatsune Miku, a version of a singing synthesizer application software that has inspired not only song creation but also songwriting, illustration, and video editing. As described herein, creators of interact to create new contents through their social network. In this paper, we analyzed the process of developing thousands of videos based on creators' social networks and investigate relationships among creation activity and social networks. The social network reveals interesting features. Creators generate large and sparse social networks including some centralized communities, and such centralized community's members shared special tags. Different categories of creators have different roles in evolving the network, e.g., songwriters gather more links than other categories, implying that they are triggers to network evolution.

Creation of Audiovisual Presentations as a Tool to Develop Key Competences in Secondary-School Students. A Case Study in Science Class

ERIC Educational Resources Information Center

Ezquerra, Ángel; Manso, Javier; Burgos, Mª Esther; Hallabrin, Carla

2014-01-01

New curricular plans based on key competences create the need for new educational proposals that allow their development. This article describes a proposal to develop key competences through project-based learning. The project's objective is the creation of a digital video. The following study was carried out with students in their final two years…

Information Technology Tools Analysis in Quantitative Courses of IT-Management (Case Study: M.Sc.-Tehran University)

ERIC Educational Resources Information Center

Eshlaghy, Abbas Toloie; Kaveh, Haydeh

2009-01-01

The purpose of this study was to determine the most suitable ICT-based education and define the most suitable e-content creation tools for quantitative courses in the IT-management Masters program. ICT-based tools and technologies are divided in to three categories: the creation of e-content, the offering of e-content, and access to e-content. In…

Geometry creation for MCNP by Sabrina and XSM

DOE Office of Scientific and Technical Information (OSTI.GOV)

Van Riper, K.A.

The Monte Carlo N-Particle transport code MCNP is based on a surface description of 3-dimensional geometry. Cells are defined in terms of boolean operations on signed quadratic surfaces. MCNP geometry is entered as a card image file containing coefficients of the surface equations and a list of surfaces and operators describing cells. Several programs are available to assist in creation of the geometry specification, among them Sabrina and the new ``Smart Editor`` code XSM. We briefly describe geometry creation in Sabrina and then discuss XSM in detail. XSM is under development; our discussion is based on the state of XSMmore » as of January 1, 1994.« less

Cambrian archaeocyathan metazoans: revision of morphological characters and standardization of genus descriptions to establish an online identification tool.

PubMed Central

Kerner, Adeline; Debrenne, Françoise; Vignes-Lebbe, Régine

2011-01-01

Abstract Archaeocyatha represent the oldest calcified sponges and the first metazoans to build bioconstructions in association with calcimicrobes. They are a key group in biology, evolutionary studies, biostratigraphy, paleoecology and paleogeography of the early Cambrian times. The establishing of a new standardized terminology for archaeocyathans description has permitted the creation of the first knowledge base in English including descriptions of all archaeocyathan genera. This base, using the XPER² software package, is an integral part of the -Archaeocyatha- a knowledge base website, freely available at url http://www.infosyslab.fr/archaeocyatha. The website is composed of common information about Archaeocyatha, general remarks about the knowledge base, the description of the 307 genera recognized with images of type-specimens of type-species for each genus, as well as additional morphological data, an interactive free access key and its user guide. The automatic analysis and comparison of the digitized descriptions have identified some genera with highly similar morphology. These results are a great help for future taxonomic revisions and suggest a number of possible synonymies that require further study. PMID:22207818

f-treeGC: a questionnaire-based family tree-creation software for genetic counseling and genome cohort studies.

PubMed

Tokutomi, Tomoharu; Fukushima, Akimune; Yamamoto, Kayono; Bansho, Yasushi; Hachiya, Tsuyoshi; Shimizu, Atsushi

2017-07-14

The Tohoku Medical Megabank project aims to create a next-generation personalized healthcare system by conducting large-scale genome-cohort studies involving three generations of local residents in the areas affected by the Great East Japan Earthquake. We collected medical and genomic information for developing a biobank to be used for this healthcare system. We designed a questionnaire-based pedigree-creation software program named "f-treeGC," which enables even less experienced medical practitioners to accurately and rapidly collect family health history and create pedigree charts. f-treeGC may be run on Adobe AIR. Pedigree charts are created in the following manner: 1) At system startup, the client is prompted to provide required information on the presence or absence of children; f-treeGC is capable of creating a pedigree up to three generations. 2) An interviewer fills out a multiple-choice questionnaire on genealogical information. 3) The information requested includes name, age, gender, general status, infertility status, pregnancy status, fetal status, and physical features or health conditions of individuals over three generations. In addition, information regarding the client and the proband, and birth order information, including multiple gestation, custody, multiple individuals, donor or surrogate, adoption, and consanguinity may be included. 4) f-treeGC shows only marriages between first cousins via the overlay function. 5) f-treeGC automatically creates a pedigree chart, and the chart-creation process is visible for inspection on the screen in real time. 6) The genealogical data may be saved as a file in the original format. The created/modified date and time may be changed as required, and the file may be password-protected and/or saved in read-only format. To enable sorting or searching from the database, the file name automatically contains the terms typed into the entry fields, including physical features or health conditions, by default. 7) Alternatively, family histories are collected using a completed foldable interview paper sheet named "f-sheet", which is identical to the questionnaire in f-treeGC. We developed a questionnaire-based family tree-creation software, named f-treeGC, which is fully compliant with international recommendations for standardized human pedigree nomenclature. The present software simplifies the process of collecting family histories and pedigrees, and has a variety of uses, from genome cohort studies or primary care to genetic counseling.

Polyamide membranes with nanoscale Turing structures for water purification

NASA Astrophysics Data System (ADS)

Tan, Zhe; Chen, Shengfu; Peng, Xinsheng; Zhang, Lin; Gao, Congjie

2018-05-01

The emergence of Turing structures is of fundamental importance, and designing these structures and developing their applications have practical effects in chemistry and biology. We use a facile route based on interfacial polymerization to generate Turing-type polyamide membranes for water purification. Manipulation of shapes by control of reaction conditions enabled the creation of membranes with bubble or tube structures. These membranes exhibit excellent water-salt separation performance that surpasses the upper-bound line of traditional desalination membranes. Furthermore, we show the existence of high water permeability sites in the Turing structures, where water transport through the membranes is enhanced.

Using Cesium for 3D Thematic Visualisations on the Web

NASA Astrophysics Data System (ADS)

Gede, Mátyás

2018-05-01

Cesium (http://cesiumjs.org) is an open source, WebGL-based JavaScript library for virtual globes and 3D maps. It is an excellent tool for 3D thematic visualisations, but to use its full functionality it has to be feed with its own file format, CZML. Unfortunately, this format is not yet supported by any major GIS software. This paper intro- duces a plugin for QGIS, developed by the author, which facilitates the creation of CZML file for various types of visualisations. The usability of Cesium is also examined in various hardware/software environments.

Internet-based site-specific interventions for syphilis prevention among gay and bisexual men.

PubMed

Klausner, J D; Levine, D K; Kent, C K

2004-11-01

Recent increases in syphilis in gay men in urban areas in the US and Europe have been associated with men meeting new sex partners on the Internet in chat-rooms and at websites that facilitate partner meeting. In response to the syphilis epidemic in San Francisco, the San Francisco Department of Public Health partnered with a community-based organization, Internet Sexuality Information Services, Inc., to develop, implement and evaluate a broad range of innovative Internet-based prevention interventions including the creation of a website, individual online outreach, banner advertisements, chats, an educational site, message boards, warnings and an online syphilis testing program. This paper documents the varied success of these interventions with process measures and calls for greater emphasis on impact measures in the evaluation of these types of intervention.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dorey, Patrick; Halavanau, Aliaksei; Mercer, James

Here, we study boundary scattering in themore » $$\\phi^4$$ model on a half-line with a one-parameter family of Neumann-type boundary conditions. A rich variety of phenomena is observed, which extends previously-studied behaviour on the full line to include regimes of near-elastic scattering, the restoration of a missing scattering window, and the creation of a kink or oscillon through the collision-induced decay of a metastable boundary state. We also study the decay of the vibrational boundary mode, and explore different scenarios for its relaxation and for the creation of kinks.« less

Application of ultrasonic sensor for measuring distances in robotics

NASA Astrophysics Data System (ADS)

Zhmud, V. A.; Kondratiev, N. O.; Kuznetsov, K. A.; Trubin, V. G.; Dimitrov, L. V.

2018-05-01

Ultrasonic sensors allow us to equip robots with a means of perceiving surrounding objects, an alternative to technical vision. Humanoid robots, like robots of other types, are, first, equipped with sensory systems similar to the senses of a human. However, this approach is not enough. All possible types and kinds of sensors should be used, including those that are similar to those of other animals and creations (in particular, echolocation in dolphins and bats), as well as sensors that have no analogues in the wild. This paper discusses the main issues that arise when working with the HC-SR04 ultrasound rangefinder based on the STM32VLDISCOVERY evaluation board. The characteristics of similar modules for comparison are given. A subroutine for working with the sensor is given.

Towards an easier creation of three-dimensional data for embedding into scholarly 3D PDF (Portable Document Format) files

PubMed Central

2015-01-01

The Portable Document Format (PDF) allows for embedding three-dimensional (3D) models and is therefore particularly suitable to communicate respective data, especially as regards scholarly articles. The generation of the necessary model data, however, is still challenging, especially for inexperienced users. This prevents an unrestrained proliferation of 3D PDF usage in scholarly communication. This article introduces a new solution for the creation of three of types of 3D geometry (point clouds, polylines and triangle meshes), that is based on MeVisLab, a framework for biomedical image processing. This solution enables even novice users to generate the model data files without requiring programming skills and without the need for an intensive training by simply using it as a conversion tool. Advanced users can benefit from the full capability of MeVisLab to generate and export the model data as part of an overall processing chain. Although MeVisLab is primarily designed for handling biomedical image data, the new module is not restricted to this domain. It can be used for all scientific disciplines. PMID:25780759

Towards an easier creation of three-dimensional data for embedding into scholarly 3D PDF (Portable Document Format) files.

PubMed

Newe, Axel

2015-01-01

The Portable Document Format (PDF) allows for embedding three-dimensional (3D) models and is therefore particularly suitable to communicate respective data, especially as regards scholarly articles. The generation of the necessary model data, however, is still challenging, especially for inexperienced users. This prevents an unrestrained proliferation of 3D PDF usage in scholarly communication. This article introduces a new solution for the creation of three of types of 3D geometry (point clouds, polylines and triangle meshes), that is based on MeVisLab, a framework for biomedical image processing. This solution enables even novice users to generate the model data files without requiring programming skills and without the need for an intensive training by simply using it as a conversion tool. Advanced users can benefit from the full capability of MeVisLab to generate and export the model data as part of an overall processing chain. Although MeVisLab is primarily designed for handling biomedical image data, the new module is not restricted to this domain. It can be used for all scientific disciplines.

Stoma Creation and Reversal After Cytoreductive Surgery with Hyperthermic Intraperitoneal Chemotherapy.

PubMed

Doud, Andrea N; Levine, Edward A; Fino, Nora F; Stewart, John H; Shen, Perry; Votanopoulos, Konstantinos I

2016-02-01

Cytoreductive surgery with heated intraperitoneal chemotherapy (CRS/HIPEC) often includes stoma creation. We evaluated the indications, morbidity, and mortality associated with stoma creation and reversal after CRS/HIPEC. Retrospective analysis of a prospective database of 1149 CRS-HIPEC procedures was performed. Patient demographics, type of malignancy, comorbidities, Clavien-graded morbidity, mortality, indications for stoma creation, and outcomes of subsequent reversal were abstracted. Sixteen percent (186/1149) of CRS/HIPEC procedures included stoma creation, whereas 1.1 % (11/963) of patients without initial stoma creation developed anastomotic leaks requiring stoma. Patients who required a stoma had worse preoperative performance status (ECOG 0/1: 77.2 vs. 86.1 %, p = 0.002), greater burden of disease (PCI 17.6 vs. 12.9, p < 0.0001), and were more likely to have R2 resections (74.5 vs. 48.8 %, p < 0.0001) than those without stoma creation. Stomas were intended to be permanent in 17.5 % (35/199). Of 164 patients with potentially reversible ostomies, only 26.2 % (43/164) underwent reversal. Disease progression (43/164, 26.2 %) and death (40/164, 24.3 %) most commonly precluded reversal. After reversal, 27.9 % (12/43) suffered a Clavien I/II morbidity, 27.9 % (12/43) suffered Clavien III/IV morbidity, and 30-day mortality was 4.7 % (2/43). Anastomotic leak occurred after 9 % (3/33) of ileostomy and 10 % (1/10) of colostomy reversals. Stomas are more common among CRS/HIPEC patients with a high burden of disease and poor functional status. Reversal is uncommon and is associated with significant major morbidity. Preoperative counseling for those with high disease burden and poor functional status should include the risk of permanent stoma.

Influence of wetland type, hydrology, and wetland destruction on aquatic communities within wetland reservoir subirrigation systems in northwestern Ohio

USDA-ARS?s Scientific Manuscript database

Establishment of an agricultural water recycling system known as the wetland reservoir subirrigation system (WRSIS) results in the creation of two different types of wetlands adjacent to agricultural fields. Each WRSIS consists of one treatment wetland designed to process agricultural contaminants (...

36 CFR § 1222.12 - What types of documentary materials are Federal records?

Code of Federal Regulations, 2013 CFR

2013-07-01

... 36 Parks, Forests, and Public Property 3 2013-07-01 2012-07-01 true What types of documentary materials are Federal records? § 1222.12 Section § 1222.12 Parks, Forests, and Public Property NATIONAL ARCHIVES AND RECORDS ADMINISTRATION RECORDS MANAGEMENT CREATION AND MAINTENANCE OF FEDERAL RECORDS...

BDVC (Bimodal Database of Violent Content): A database of violent audio and video

NASA Astrophysics Data System (ADS)

Rivera Martínez, Jose Luis; Mijes Cruz, Mario Humberto; Rodríguez Vázqu, Manuel Antonio; Rodríguez Espejo, Luis; Montoya Obeso, Abraham; García Vázquez, Mireya Saraí; Ramírez Acosta, Alejandro Álvaro

2017-09-01

Nowadays there is a trend towards the use of unimodal databases for multimedia content description, organization and retrieval applications of a single type of content like text, voice and images, instead bimodal databases allow to associate semantically two different types of content like audio-video, image-text, among others. The generation of a bimodal database of audio-video implies the creation of a connection between the multimedia content through the semantic relation that associates the actions of both types of information. This paper describes in detail the used characteristics and methodology for the creation of the bimodal database of violent content; the semantic relationship is stablished by the proposed concepts that describe the audiovisual information. The use of bimodal databases in applications related to the audiovisual content processing allows an increase in the semantic performance only and only if these applications process both type of content. This bimodal database counts with 580 audiovisual annotated segments, with a duration of 28 minutes, divided in 41 classes. Bimodal databases are a tool in the generation of applications for the semantic web.

Creationism Challenges Geology: A Retreat to the Eighteenth Century.

ERIC Educational Resources Information Center

Eglin, Paula G.; Graham, Mildred W.

1982-01-01

Some contentions of scientific creationism that conflict with accepted principles of geology (catastrophism, fossil records, earth's age, rock formation, second law of thermodynamics) are reviewed, demonstrating that these claims are based not on scientific research or reasonable conjecture but on Biblical references. (Author/DC)

Machine Readable Bibliographic Records: Criteria and Creation.

ERIC Educational Resources Information Center

Bregzis, Ritvars

The centrality of bibliographic records in library automation, objectives of the bibliographic record file and elemental factors involved in bibliographic record creation are discussed. The practical work of creating bibliographic records involves: (1) data base environment, (2) technical aspects, (3) cost and (4) operational methodology. The…

Toward “Green” Hybrid Materials: Core–Shell Particles with Enhanced Impact Energy Absorbing Ability

PubMed Central

2016-01-01

Restrained properties of “green” degradable products drive the creation of materials with innovative structures and retained eco-attributes. Herein, we introduce the creation of impact modifiers in the form of core–shell (CS) particles toward the creation of “green” composite materials. Particles with CS structure constituted of PLA stereocomplex (PLASC) and a rubbery phase of poly(ε-caprolactone-co-d,l-lactide) (P[CL-co-LA]) were successfully achieved by spray droplet atomization. A synergistic association of the soft P[CL-co-LA] and hard PLASC domains in the core–shell structure induced unique thermo-mechanical effects on the PLA-based composites. The core–shell particles enhanced the crystallization of PLA matrices by acting as nucleating agents. The core–shell particles functioned efficiently as impact modifiers with minimal effect on the composites stiffness and strength. These findings provide a new platform for scalable design of polymeric-based structures to be used in the creation of advanced degradable materials. PMID:29503773

Thermodynamics of cosmological matter creation.

PubMed

Prigogine, I; Geheniau, J; Gunzig, E; Nardone, P

1988-10-01

A type of cosmological history that includes large-scale entropy production is proposed. These cosmologies are based on reinterpretation of the matter-energy stress tensor in Einstein's equations. This modifies the usual adiabatic energy conservation laws, thereby including irreversible matter creation. This creation corresponds to an irreversible energy flow from the gravitational field to the created matter constituents. This point of view results from consideration of the thermodynamics of open systems in the framework of cosmology. It is shown that the second law of thermodynamics requires that space-time transforms into matter, while the inverse transformation is forbidden. It appears that the usual initial singularity associated with the big bang is structurally unstable with respect to irreversible matter creation. The corresponding cosmological history therefore starts from an instability of the vacuum rather than from a singularity. This is exemplified in the framework of a simple phenomenological model that leads to a three-stage cosmology: the first drives the cosmological system from the initial instability to a de Sitter regime, and the last connects with the usual matter-radiation Robertson-Walker universe. Matter as well as entropy creation occurs during the first two stages, while the third involves the traditional cosmological evolution. A remarkable fact is that the de Sitter stage appears to be an attractor independent of the initial fluctuation. This is also the case for all the physical predictions involving the present Robertson-Walker universe. Most results obtained previously, in the framework of quantum field theory, can now be obtained on a macroscopic basis. It is shown that this description leads quite naturally to the introduction of primeval black holes as the intermediate stage between the Minkowski vacuum and the present matter-radiation universe. The instability at the origin of the universe is the result of fluctuations of the vacuum in which black holes act as membranes that stabilize these fluctuations. In short, black holes will be produced by and "inverse" Hawking radiation process and, once formed, will decompose into "real" matter through the usual Hawking radiation. In this way, the irreversible transformation of space-time into matter can be described as a phase separation between matter and gravitation in which black holes play the role of "critical nuclei."

Consumer Participation in Co-creation: An Enlightening Model of Causes and Effects Based on Ethical Values and Transcendent Motives.

PubMed

Martínez-Cañas, Ricardo; Ruiz-Palomino, Pablo; Linuesa-Langreo, Jorge; Blázquez-Resino, Juan J

2016-01-01

In the current highly interconnected modern world, the role of consumers has changed substantially due to their active collaboration with companies in product and process innovation. Specifically, consumer participation has become key to the development of successful products and services, as companies have come to rely more and more on consumers' opinion as a source of innovative ideas and brand value. However, whereas existing research has focused on identifying the different elements involved in consumers' co-creation, there is still the need to comprehend better this complex mechanism by integrating distinct dimensional insights. With an integrative review of research into three important perspectives, one nurturing from the Service-Dominant logic, another one based on the information and communication technologies (ICTs) platforms, and (the ethical values-driven) Marketing 3.0 paradigm, this article proposes a conceptual framework in which consumers' ethical values and transcendent motivations play an important role in encouraging their engagement in co-creation activities. In this connection, and with consumers increasingly embracing the need to fulfill a social and ethical function in society, the co-creation process is here comprehended as a means to emphasize the social and moral aspects of co-creation. This article also identifies the important, supportive role of the Marketing 3.0 paradigm and Web 3.0 tools to initiate the co-creation process, as well as the important valuable benefits attained by both companies and consumers after consumers engage in this process. Importantly, these benefits are highlighted to increase when ethical products are the object of these co-creation activities. All these insights have notable implications for both research and managerial practice.

Consumer Participation in Co-creation: An Enlightening Model of Causes and Effects Based on Ethical Values and Transcendent Motives

PubMed Central

Martínez-Cañas, Ricardo; Ruiz-Palomino, Pablo; Linuesa-Langreo, Jorge; Blázquez-Resino, Juan J.

2016-01-01

In the current highly interconnected modern world, the role of consumers has changed substantially due to their active collaboration with companies in product and process innovation. Specifically, consumer participation has become key to the development of successful products and services, as companies have come to rely more and more on consumers' opinion as a source of innovative ideas and brand value. However, whereas existing research has focused on identifying the different elements involved in consumers' co-creation, there is still the need to comprehend better this complex mechanism by integrating distinct dimensional insights. With an integrative review of research into three important perspectives, one nurturing from the Service-Dominant logic, another one based on the information and communication technologies (ICTs) platforms, and (the ethical values-driven) Marketing 3.0 paradigm, this article proposes a conceptual framework in which consumers' ethical values and transcendent motivations play an important role in encouraging their engagement in co-creation activities. In this connection, and with consumers increasingly embracing the need to fulfill a social and ethical function in society, the co-creation process is here comprehended as a means to emphasize the social and moral aspects of co-creation. This article also identifies the important, supportive role of the Marketing 3.0 paradigm and Web 3.0 tools to initiate the co-creation process, as well as the important valuable benefits attained by both companies and consumers after consumers engage in this process. Importantly, these benefits are highlighted to increase when ethical products are the object of these co-creation activities. All these insights have notable implications for both research and managerial practice. PMID:27303349

Comparison of Multi-Scale Digital Elevation Models for Defining Waterways and Catchments Over Large Areas

NASA Astrophysics Data System (ADS)

Harris, B.; McDougall, K.; Barry, M.

2012-07-01

Digital Elevation Models (DEMs) allow for the efficient and consistent creation of waterways and catchment boundaries over large areas. Studies of waterway delineation from DEMs are usually undertaken over small or single catchment areas due to the nature of the problems being investigated. Improvements in Geographic Information Systems (GIS) techniques, software, hardware and data allow for analysis of larger data sets and also facilitate a consistent tool for the creation and analysis of waterways over extensive areas. However, rarely are they developed over large regional areas because of the lack of available raw data sets and the amount of work required to create the underlying DEMs. This paper examines definition of waterways and catchments over an area of approximately 25,000 km2 to establish the optimal DEM scale required for waterway delineation over large regional projects. The comparative study analysed multi-scale DEMs over two test areas (Wivenhoe catchment, 543 km2 and a detailed 13 km2 within the Wivenhoe catchment) including various data types, scales, quality, and variable catchment input parameters. Historic and available DEM data was compared to high resolution Lidar based DEMs to assess variations in the formation of stream networks. The results identified that, particularly in areas of high elevation change, DEMs at 20 m cell size created from broad scale 1:25,000 data (combined with more detailed data or manual delineation in flat areas) are adequate for the creation of waterways and catchments at a regional scale.

Investigating Knowledge Creation Technology in an Engineering Course

ERIC Educational Resources Information Center

Jalonen, Satu; Lakkala, Minna; Paavola, Sami

2011-01-01

The aim of the present study was to examine the technological affordances of a web-based collaborative learning technology, Knowledge Practices Environment (KPE), for supporting different dimensions of knowledge creation processes. KPE was used by engineering students in a practically oriented undergraduate engineering course. The study…

Dynamical Reference Frame - Current Relevance and Future Prospects

DTIC Science & Technology

2000-03-01

mentioned that the concepts of ecliptic , obliquity , and mean equator are now obsolete in the context of modern ephemeris creation. 2. Ephemerides...based upon the ICRF, there is no longer an explicit use of the celestial equator, equinox, or ecliptic in the ephemeris creation process. These elements

Complication rates of ostomy surgery are high and vary significantly between hospitals.

PubMed

Sheetz, Kyle H; Waits, Seth A; Krell, Robert W; Morris, Arden M; Englesbe, Michael J; Mullard, Andrew; Campbell, Darrell A; Hendren, Samantha

2014-05-01

Ostomy surgery is common and has traditionally been associated with high rates of morbidity and mortality, suggesting an important target for quality improvement. The purpose of this work was to evaluate the variation in outcomes after ostomy creation surgery within Michigan to identify targets for quality improvement. This was a retrospective cohort study. The study took place within the 34-hospital Michigan Surgical Quality Collaborative. Patients included were those undergoing ostomy creation surgery between 2006 and 2011. We evaluated hospital morbidity and mortality rates after risk adjustment (age, comorbidities, emergency vs elective, and procedure type). A total of 4250 patients underwent ostomy creation surgery; 3866 procedures (91.0%) were open and 384 (9.0%) were laparoscopic. Unadjusted morbidity and mortality rates were 43.9% and 10.7%. Unadjusted morbidity rates for specific procedures ranged from 32.7% for ostomy-creation-only procedures to 47.8% for Hartmann procedures. Risk-adjusted morbidity rates varied significantly between hospitals, ranging from 31.2% (95% CI, 18.4-43.9) to 60.8% (95% CI, 48.9-72.6). There were 5 statistically significant high-outlier hospitals and 3 statistically significant low-outlier hospitals for risk-adjusted morbidity. The pattern of complication types was similar between high- and low-outlier hospitals. Case volume, operative duration, and use of laparoscopic surgery did not explain the variation in morbidity rates across hospitals. This work was limited by its retrospective study design, by unmeasured variation in case severity, and by our inability to differentiate between colostomies and ileostomies because of the use of Current Procedural Terminology codes. Morbidity and mortality rates for modern ostomy surgery are high. Although this type of surgery has received little attention in healthcare policy, these data reveal that it is both common and uncommonly morbid. Variation in hospital performance provides an opportunity to identify quality improvement practices that could be disseminated among hospitals.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pin, F.G.; Bender, S.R.

Most fuzzy logic-based reasoning schemes developed for robot control are fully reactive, i.e., the reasoning modules consist of fuzzy rule bases that represent direct mappings from the stimuli provided by the perception systems to the responses implemented by the motion controllers. Due to their totally reactive nature, such reasoning systems can encounter problems such as infinite loops and limit cycles. In this paper, we proposed an approach to remedy these problems by adding a memory and memory-related behaviors to basic reactive systems. Three major types of memory behaviors are addressed: memory creation, memory management, and memory utilization. These are firstmore » presented, and examples of their implementation for the recognition of limit cycles during the navigation of an autonomous robot in a priori unknown environments are then discussed.« less

Applying Community-Based Participatory Research to Create a Diabetes Prevention Documentary with New Zealand Māori.

PubMed

Farmer, Alison; Gage, Jeffrey; Kirk, Ray; Edgar, Timothy

2016-01-01

Type 2 diabetes is almost three times more prevalent in the indigenous people of New Zealand (Māori) than non-Māori. Despite the high rate of diabetes in the Māori population, little is known about their personal understanding or experience of the disease. To engage Māori in a participatory process to develop a culturally relevant diabetes prevention documentary. Principles of community-based participatory research (CBPR) were applied to a qualitative research design employing key informant interviews and focus groups to develop a diabetes prevention documentary. A CBPR approach provides an appropriate model for enacting local action-oriented approaches in the creation of a documentary that reflects Māori cultural beliefs and practices.

Developing a modular architecture for creation of rule-based clinical diagnostic criteria.

PubMed

Hong, Na; Pathak, Jyotishman; Chute, Christopher G; Jiang, Guoqian

2016-01-01

With recent advances in computerized patient records system, there is an urgent need for producing computable and standards-based clinical diagnostic criteria. Notably, constructing rule-based clinical diagnosis criteria has become one of the goals in the International Classification of Diseases (ICD)-11 revision. However, few studies have been done in building a unified architecture to support the need for diagnostic criteria computerization. In this study, we present a modular architecture for enabling the creation of rule-based clinical diagnostic criteria leveraging Semantic Web technologies. The architecture consists of two modules: an authoring module that utilizes a standards-based information model and a translation module that leverages Semantic Web Rule Language (SWRL). In a prototype implementation, we created a diagnostic criteria upper ontology (DCUO) that integrates ICD-11 content model with the Quality Data Model (QDM). Using the DCUO, we developed a transformation tool that converts QDM-based diagnostic criteria into Semantic Web Rule Language (SWRL) representation. We evaluated the domain coverage of the upper ontology model using randomly selected diagnostic criteria from broad domains (n = 20). We also tested the transformation algorithms using 6 QDM templates for ontology population and 15 QDM-based criteria data for rule generation. As the results, the first draft of DCUO contains 14 root classes, 21 subclasses, 6 object properties and 1 data property. Investigation Findings, and Signs and Symptoms are the two most commonly used element types. All 6 HQMF templates are successfully parsed and populated into their corresponding domain specific ontologies and 14 rules (93.3 %) passed the rule validation. Our efforts in developing and prototyping a modular architecture provide useful insight into how to build a scalable solution to support diagnostic criteria representation and computerization.

Stakeholder views on the creation and use of genetically-engineered animals in research.

PubMed

Ormandy, Elisabeth H

2016-05-01

This interview-based study examined the diversity of views relating to the creation and use of genetically-engineered (GE) animals in biomedical science. Twenty Canadian participants (eight researchers, five research technicians and seven members of the public) took part in the interviews, in which four main themes were discussed: a) how participants felt about the genetic engineering of animals as a practice; b) governance of the creation and use of GE animals in research, and whether current guidelines are sufficient; c) the Three Rs (Replacement, Reduction, Refinement) and how they are applied during the creation and use of GE animals in research; and d) whether public opinion should play a greater role in the creation and use of GE animals. Most of the participants felt that the creation and use of GE animals for biomedical research purposes (as opposed to food purposes) is acceptable, provided that tangible human health benefits are gained. However, obstacles to Three Rs implementation were identified, and the participants agreed that more effort should be placed on engaging the public on the use of GE animals in research. 2016 FRAME.

12 CFR 745.1 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-01-01

... a credit union of a type approved by the Board which evidences money or its equivalent received or... paragraph (c) of this section, or any principal department of such public unit, (1) the creation of which...

[Platonic conception of a man as an element of the universe on the base of dialogue "Timajos"].

PubMed

Ziaja, Jacek

2002-01-01

Dialogue "Timajos" states Plato's lecture on a nature of the universe with special regard for position of a man. Presented in it ideas are based in a considerable degree on the knowledge of earlier thinkers, first of all Phytagoreans. They concern problems of primeval matter properties and world creation based on the rules of geometry. Afterwords the question of soul bestowal on the world and creation of living beings, connected directly with a problem of metempsychosis, are discussed. In the final part of the dialogue Plato focuses his attention on a corporal dimension of human structure. On the basis of triangle theory he describes creation of internal organs, skeleton, blood vessels and organs of senses, their function and the processes of growing old and death of the body. In the whole lecture an attention is brought to disclosure the effect of mind in the universe and purposefulness of creator activity.

Human Activity Modeling and Simulation with High Biofidelity

DTIC Science & Technology

2013-01-01

Human activity Modeling and Simulation (M&S) plays an important role in simulation-based training and Virtual Reality (VR). However, human activity M...kinematics and motion mapping/creation; and (e) creation and replication of human activity in 3-D space with true shape and motion. A brief review is

Curiosity and Its Role in Cross-Cultural Knowledge Creation

ERIC Educational Resources Information Center

Mikhaylov, Natalie S.

2016-01-01

This paper explores the role of curiosity in promoting cross-cultural knowledge creation and competence development. It is based on a study with four international higher educational institutions, all of which offer management and business education for local and international students. The reality of multicultural and intercultural relationships…

Collaboration, Innovation, and Value Creation in a Global Telecom

ERIC Educational Resources Information Center

Allee, Verna; Taug, Jan

2006-01-01

Purpose: The purpose of this paper is to review a systemic organizational change initiative for improving collaboration, innovation and value creation at a global telecom. Design/methodology/approach: Based on a comprehensive internal assessment Telenor identified core issues and challenges in supporting collaboration after several years of…

Polite, Instrumental, and Dual Liars: Relation to Children's Developing Social Skills and Cognitive Ability

ERIC Educational Resources Information Center

Lavoie, Jennifer; Yachison, Sarah; Crossman, Angela; Talwar, Victoria

2017-01-01

Lying is an interpersonal exercise that requires the intentional creation of a false belief in another's mind. As such, children's development of lie-telling is related to their increasing understanding of others and may reflect the acquisition of basic social skills. Although certain types of lies may support social relationships, other types of…

shinyCircos: an R/Shiny application for interactive creation of Circos plot.

PubMed

Yu, Yiming; Ouyang, Yidan; Yao, Wen

2018-04-01

Creation of Circos plot is one of the most efficient approaches to visualize genomic data. However, the installation and use of existing tools to make Circos plot are challenging for users lacking of coding experiences. To address this issue, we developed an R/Shiny application shinyCircos, a graphical user interface for interactive creation of Circos plot. shinyCircos can be easily installed either on computers for personal use or on local or public servers to provide online use to the community. Furthermore, various types of Circos plots could be easily generated and decorated with simple mouse-click. shinyCircos and its manual are freely available at https://github.com/venyao/shinyCircos. shinyCircos is deployed at https://yimingyu.shinyapps.io/shinycircos/ and http://shinycircos.ncpgr.cn/ for online use. diana1983941@mail.hzau.edu.cn or yaowen@henau.edu.cn.

The Big Bang, Genesis, and Knocking on Heaven's Door

NASA Astrophysics Data System (ADS)

Gentry, Robert

2012-03-01

Michael Shermer recently upped the ante in the big bang-Genesis controversy by citing Lisa Randall's provocative claim (Science 334, 762 (2011)) that ``it is inconceivable that God could continue to intervene without introducing a material trace of his actions.'' So does Randall's and Shermer's agreement that no such evidence exists disprove God's existence? Not in my view because my 1970s Science, Nature and ARNS publications, and my article in the 1982 AAAS Western Division's Symposium Proceedings, Evolution Confronts Creation, all contain validation of God's existence via discovery of His Fingerprints of Creation and falsification of the big bang and geological evolution. These results came to wide public/scientific attention in my testimony at the 1981 Arkansas creation/evolution trial. There ACLU witness G Brent Dalrymple from the USGS -- and 2005 Medal of Science recipient from President Bush -- admitted I had discovered a tiny mystery (primordial polonium radiohalos) in granite rocks that indicated their almost instant creation. As a follow-up in 1992 and 1995 he sent out SOS letters to the entire AGU membership that the polonium halo evidence for fiat creation still existed and that someone needed to urgently find a naturalistic explanation for them. Is the physics community guilty of a Watergate-type cover-up of this discovery of God's existence and falsification of the big bang? For the answer see www.halos.tv.

Boundary scattering in the Φ$$^{4}$$ model

DOE PAGES

Dorey, Patrick; Halavanau, Aliaksei; Mercer, James; ...

2017-05-19

Here, we study boundary scattering in themore » $$\\phi^4$$ model on a half-line with a one-parameter family of Neumann-type boundary conditions. A rich variety of phenomena is observed, which extends previously-studied behaviour on the full line to include regimes of near-elastic scattering, the restoration of a missing scattering window, and the creation of a kink or oscillon through the collision-induced decay of a metastable boundary state. We also study the decay of the vibrational boundary mode, and explore different scenarios for its relaxation and for the creation of kinks.« less

The Effect of Water or Wax-based Binders on the Chemical and Morphological Characteristics of the Margin Ceramic-Framework Interface.

PubMed

Güler, Umut; de Queiroz, José Renato Cavalcanti; de Oliveira, Luiz Fernando Cappa; Canay, Senay; Ozcan, Mutlu

2015-09-01

This study evaluated the effect of binder choice in mixing ceramic powder on the chemical and morphological features between the margin ceramic-framework interfaces. Titanium and zirconia frameworks (15 x 5 x 0.5 mm3) were veneered with margin ceramics prepared with two different binders, namely a) water/conventional or b) wax-based. For each zirconia framework material, four different margin ceramics were used: a- Creation Zi (Creation Willi Geller International); b- GC Initial Zr (GC America); Triceram (Dentaurum); and d- IPS emax (voclar Vivadent). For the titanium framework, three different margin ceramics were used: a- Creation Ti (Creation Willi Geller International); b- Triceram (Dentaurum); and c- VITA Titaniumkeramik (Vita Zahnfabrik). The chemical composition of the framework-margin ceramic interface was analyzed using Energy Dispersive X-ray Spectroscopy (EDS) and porosity level was quantified within the margin ceramic using an image program (ImageJ) from four random areas (100 x 100 pixels) on each SEM image. EDS analysis showed the presence of Carbon at the margin ceramic-framework interface in the groups where wax-based binder technique was used with the concentration being the highest for the IPS emax ZirCAD group. While IPS system (IPS ZirCAD and IPS Emax) presented higher porosity concentration using wax binder, in the other groups wax-based binder reduced the porosity of margin ceramic, except for Titanium - Triceram combination.

Universal Verification Methodology Based Register Test Automation Flow.

PubMed

Woo, Jae Hun; Cho, Yong Kwan; Park, Sun Kyu

2016-05-01

In today's SoC design, the number of registers has been increased along with complexity of hardware blocks. Register validation is a time-consuming and error-pron task. Therefore, we need an efficient way to perform verification with less effort in shorter time. In this work, we suggest register test automation flow based UVM (Universal Verification Methodology). UVM provides a standard methodology, called a register model, to facilitate stimulus generation and functional checking of registers. However, it is not easy for designers to create register models for their functional blocks or integrate models in test-bench environment because it requires knowledge of SystemVerilog and UVM libraries. For the creation of register models, many commercial tools support a register model generation from register specification described in IP-XACT, but it is time-consuming to describe register specification in IP-XACT format. For easy creation of register model, we propose spreadsheet-based register template which is translated to IP-XACT description, from which register models can be easily generated using commercial tools. On the other hand, we also automate all the steps involved integrating test-bench and generating test-cases, so that designers may use register model without detailed knowledge of UVM or SystemVerilog. This automation flow involves generating and connecting test-bench components (e.g., driver, checker, bus adaptor, etc.) and writing test sequence for each type of register test-case. With the proposed flow, designers can save considerable amount of time to verify functionality of registers.

Creation of a bovine herpes virus 1 (BoHV-1) quantitative particle standard by transmission electron microscopy and comparison with established standards for use in real-time PCR.

PubMed

Hoferer, Marc; Braun, Anne; Sting, Reinhard

2017-07-01

Standards are pivotal for pathogen quantification by real-time PCR (qPCR); however, the creation of a complete and universally applicable virus particle standard is challenging. In the present study a procedure based on purification of bovine herpes virus type 1 (BoHV-1) and subsequent quantification by transmission electron microscopy (TEM) is described. Accompanying quantitative quality controls of the TEM preparation procedure using qPCR yielded recovery rates of more than 95% of the BoHV-1 virus particles on the grid used for virus counting, which was attributed to pre-treatment of the grid with 5% bovine albumin. To compare the value of the new virus particle standard for use in qPCR, virus counter based quantification and established pure DNA standards represented by a plasmid and an oligonucleotide were included. It could be shown that the numbers of virus particles, plasmid and oligonucleotide equivalents were within one log10 range determined on the basis of standard curves indicating that different approaches provide comparable quantitative values. However, only virus particles represent a complete, universally applicable quantitative virus standard that meets the high requirements of an RNA and DNA virus gold standard. In contrast, standards based on pure DNA have to be considered as sub-standard due to limited applications. Copyright © 2017 International Alliance for Biological Standardization. Published by Elsevier Ltd. All rights reserved.

Determination of power and moment on shaft of special asynchronous electric drives

NASA Astrophysics Data System (ADS)

Karandey, V. Yu; Popov, B. K.; Popova, O. B.; Afanasyev, V. L.

2018-03-01

In the article, questions and tasks of determination of power and the moment on a shaft of special asynchronous electric drives are considered. Use of special asynchronous electric drives in mechanical engineering and other industries is relevant. The considered types of electric drives possess the improved mass-dimensional indicators in comparison with singleengine systems. Also these types of electric drives have constructive advantages; the improved characteristics allow one to realize the technological process. But creation and design of new electric drives demands adjustment of existing or development of new methods and approaches of calculation of parameters. Determination of power and the moment on a shaft of special asynchronous electric drives is the main objective during design of electric drives. This task has been solved based on a method of electromechanical transformation of energy.

Training for Template Creation: A Performance Improvement Method

ERIC Educational Resources Information Center

Lyons, Paul

2008-01-01

Purpose: There are three purposes to this article: first, to offer a training approach to employee learning and performance improvement that makes use of a step-by-step process of skill/knowledge creation. The process offers follow-up opportunities for skill maintenance and improvement; second, to explain the conceptual bases of the approach; and…

Enabling PBPK model development through the application of freely available techniques for the creation of a chemically-annotatedcollection of literature

EPA Science Inventory

The creation of Physiologically Based Pharmacokinetic (PBPK) models for a new chemical requires the selection of an appropriate model structure and the collection of a large amount of data for parameterization. Commonly, a large proportion of the needed information is collected ...

Federal Funding Sources for Public Job Creation Initiatives.

ERIC Educational Resources Information Center

Johnson, Clifford M.; Savner, Steve

This overview on potential funding sources describes three major federal programs that can provide a financing base for public job creation initiatives serving hard-to-employ welfare recipients and non-custodial parents. Section I is an introduction. Section II focuses on the Temporary Assistance to Needy Families (TANF) block grant. Section III…

The Creation of Learner-Centred Dictionaries for Endangered Languages: A Rotuman Example

ERIC Educational Resources Information Center

Vamarasi, M.

2014-01-01

This article examines the creation of dictionaries for endangered languages (ELs). Though each dictionary is uniquely prepared for its users, all dictionaries should be based on sound principles of vocabulary learning, including the importance of lexical chunks, as emphasised by Michael Lewis in his "Lexical Approach." Many of the…

“Musical co-creation”? Exploring health-promoting potentials on the use of musical and interactive tangibles for families with children with disabilities

PubMed Central

2013-01-01

The point of departure in this text is the ongoing qualitative interdisciplinary research project RHYME (www.RHYME.no), which addresses the lack of health-promoting interactive and musical Information and Communications Technology (ICT) for families with children with severe disabilities. The project explores a new treatment paradigm based on collaborative, tangible, interactive net-based musical “smart things” with multimedia capabilities. The goal in RHYME is twofold: (1) to reduce isolation and passivity, and (2) to promote health and well-being. Co-creation is suggested as a possible path to achieving these goals, by evoking feelings, for example, or accommodating the needs to act and to create social relations; co-creation also motivates users to communicate and collaborate within (new) social relations. This article engages co-creation by incorporating aspects connected to interaction design and the field of music and health. Empirical observations will be referred to. The research question is as follows: What might co-creation imply for families of children with disabilities when musical and interactive tangibles are used as health-promoting implements? PMID:23930992

Graph Drawing Aesthetics-Created by Users, Not Algorithms.

PubMed

Purchase, H C; Pilcher, C; Plimmer, B

2012-01-01

Prior empirical work on layout aesthetics for graph drawing algorithms has concentrated on the interpretation of existing graph drawings. We report on experiments which focus on the creation and layout of graph drawings: participants were asked to draw graphs based on adjacency lists, and to lay them out "nicely." Two interaction methods were used for creating the drawings: a sketch interface which allows for easy, natural hand movements, and a formal point-and-click interface similar to a typical graph editing system. We find, in common with many other studies, that removing edge crossings is the most significant aesthetic, but also discover that aligning nodes and edges to an underlying grid is important. We observe that the aesthetics favored by participants during creation of a graph drawing are often not evident in the final product and that the participants did not make a clear distinction between the processes of creation and layout. Our results suggest that graph drawing systems should integrate automatic layout with the user's manual editing process, and provide facilities to support grid-based graph creation.

Relationship between organizational structure and creativity in teaching hospitals.

PubMed

Rezaee, Rita; Marhamati, Saadat; Nabeiei, Parisa; Marhamati, Raheleh

2014-07-01

Organization structure and manpower constitute two basic components of anorganization and both are necessary for stablishing an organization. The aim of this survey was to investigate the type of the organization structure (mechanic and organic) from viewpoint of senior and junior managers in Shiraz teaching hospitals and creativity in each of these two structures. In this cross-sectional and descriptive-analytic study, organization structure and organizational creation questionnaires were filled out by hospital managers. According to the statistical consultation and due to limited target population, the entire study population was considered as sample. Thus, the sample size in this study was 84 (12 hospitals and every hospital, n = 7). For data analysis, SPSS 14 was used and Spearman correlation coefficient and t-test were used. RESULTS showed that there is a negative association between centralization and complexity with organizational creation and its dimensions. Also there was a negative association between formalization and 4 organizational creation dimensions: reception change, accepting ambiguity, abet new view and less control outside (p=0.001). The results of this study showed that the creation in hospitals with organic structure is more than that in hospitals with mechanic structure.

Beneficial use of dredged material for habitat creation, enhancement, and restoration in New York-New Jersey Harbor.

PubMed

Yozzo, David J; Wilber, Pace; Will, Robert J

2004-10-01

A comprehensive Dredged Material Management Plan (DMMP) has been developed by the US Army Corps of Engineers, New York District (USACE-NYD) and the Port Authority of New York and New Jersey (PANY/NJ). The primary objective of the DMMP is to identify cost-effective and environmentally acceptable alternatives for the placement of dredged material derived from ongoing and proposed navigation improvements within the PANY/NJ. A significant portion of this dredged material is classified as unsuitable for open-ocean disposal. One suite of alternatives presented within the DMMP is the beneficial use of dredged material for habitat creation, enhancement, and restoration within the NY/NJ Harbor Estuary. Proposed beneficial use/habitat development projects include the use of dredged material for construction of artificial reefs, oyster reef restoration, intertidal wetland and mudflat creation, bathymetric recontouring, filling dead-end canals/basins, creation of bird/wildlife islands, and landfill/brownfields reclamation. Preliminary screening of the proposed beneficial use alternatives identified advantages, disadvantages, potential volumes, and estimated costs associated with each project type. Continued study of the proposed beneficial use alternatives has identified areas of environmental research or technology development where further investigation is warranted.

Relationship between organizational structure and creativity in teaching hospitals

PubMed Central

REZAEE, RITA; MARHAMATI, SAADAT; NABEIEI, PARISA; MARHAMATI, RAHELEH

2014-01-01

Introduction: Organization structure and manpower constitute two basic components of anorganization and both are necessary for stablishing an organization. The aim of this survey was to investigate the type of the organization structure (mechanic and organic) from viewpoint of senior and junior managers in Shiraz teaching hospitals and creativity in each of these two structures. Methods: In this cross-sectional and descriptive-analytic study, organization structure and organizational creation questionnaires were filled out by hospital managers. According to the statistical consultation and due to limited target population, the entire study population was considered as sample. Thus, the sample size in this study was 84 (12 hospitals and every hospital, n = 7). For data analysis, SPSS 14 was used and Spearman correlation coefficient and t-test were used. Results: Results showed that there is a negative association between centralization and complexity with organizational creation and its dimensions. Also there was a negative association between formalization and 4 organizational creation dimensions: reception change, accepting ambiguity, abet new view and less control outside (p=0.001). Conclusion: The results of this study showed that the creation in hospitals with organic structure is more than that in hospitals with mechanic structure. PMID:25512934

41 CFR 102-193.25 - What type of records management business process improvements should my agency strive to achieve?

Code of Federal Regulations, 2010 CFR

2010-07-01

...) FEDERAL MANAGEMENT REGULATION ADMINISTRATIVE PROGRAMS 193-CREATION, MAINTENANCE, AND USE OF RECORDS § 102... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false What type of records management business process improvements should my agency strive to achieve? 102-193.25 Section 102-193.25...

Creation of graphic database specifying android arm mechanism work envelope taking into account forbidden zones position

NASA Astrophysics Data System (ADS)

Pritykin, F. N.; Nebritov, V. I.

2017-06-01

The structure of graphic database specifying the shape and the work envelope projection position of an android arm mechanism with various positions of the known in advance forbidden zones is proposed. The technique of analytical assignment of the work envelope based on the methods of analytical geometry and theory of sets is represented. The conducted studies can be applied in creation of knowledge bases for intellectual systems of android control functioning independently in the sophisticated environment.

Simple Physics-Based Analytical Formulas for the Potentials of Mean Force of the Interaction of Amino Acid Side Chains in Water. VII. Charged-Hydrophobic/Polar and Polar-Hydrophobic/Polar Side Chains.

PubMed

Makowski, Mariusz; Liwo, Adam; Scheraga, Harold A

2017-01-19

The physics-based potentials of side-chain-side-chain interactions corresponding to pairs composed of charged and polar, polar and polar, charged and hydrophobic, and hydrophobic and hydrophobic side chains have been determined. A total of 144 four-dimensional potentials of mean force (PMFs) of all possible pairs of molecules modeling these pairs were determined by umbrella-sampling molecular dynamics simulations in explicit water as functions of distance and orientation, and the analytical expressions were then fitted to the PMFs. Depending on the type of interacting sites, the analytical approximation to the PMF is a sum of terms corresponding to van der Waals interactions and cavity-creation involving the nonpolar sections of the side chains and van der Waals, cavity-creation, and electrostatic (charge-dipole or dipole-dipole) interaction energies and polarization energies involving the charged or polar sections of the side chains. The model used in this work reproduces all features of the interacting pairs. The UNited RESidue force field with the new side-chain-side-chain interaction potentials was preliminarily tested with the N-terminal part of the B-domain of staphylococcal protein A (PDBL 1BDD ; a three-α-helix bundle) and UPF0291 protein YnzC from Bacillus subtilis (PDB: 2HEP ; an α-helical hairpin).

Sauter-Schwinger pair creation dynamically assisted by a plane wave

NASA Astrophysics Data System (ADS)

Torgrimsson, Greger; Schneider, Christian; Schützhold, Ralf

2018-05-01

We study electron-positron pair creation by a strong and constant electric field superimposed with a weaker transversal plane wave which is incident perpendicularly (or under some angle). Comparing the fully nonperturbative approach based on the world-line instanton method with a perturbative expansion into powers of the strength of the weaker plane wave, we find good agreement—provided that the latter is carried out to sufficiently high orders. As usual for the dynamically assisted Sauter-Schwinger effect, the additional plane wave induces an exponential enhancement of the pair-creation probability if the combined Keldysh parameter exceeds a certain threshold.

Creation of a small high-throughput screening facility.

PubMed

Flak, Tod

2009-01-01

The creation of a high-throughput screening facility within an organization is a difficult task, requiring a substantial investment of time, money, and organizational effort. Major issues to consider include the selection of equipment, the establishment of data analysis methodologies, and the formation of a group having the necessary competencies. If done properly, it is possible to build a screening system in incremental steps, adding new pieces of equipment and data analysis modules as the need grows. Based upon our experience with the creation of a small screening service, we present some guidelines to consider in planning a screening facility.

Splicing predictions reliably classify different types of alternative splicing

PubMed Central

Busch, Anke; Hertel, Klemens J.

2015-01-01

Alternative splicing is a key player in the creation of complex mammalian transcriptomes and its misregulation is associated with many human diseases. Multiple mRNA isoforms are generated from most human genes, a process mediated by the interplay of various RNA signature elements and trans-acting factors that guide spliceosomal assembly and intron removal. Here, we introduce a splicing predictor that evaluates hundreds of RNA features simultaneously to successfully differentiate between exons that are constitutively spliced, exons that undergo alternative 5′ or 3′ splice-site selection, and alternative cassette-type exons. Surprisingly, the splicing predictor did not feature strong discriminatory contributions from binding sites for known splicing regulators. Rather, the ability of an exon to be involved in one or multiple types of alternative splicing is dictated by its immediate sequence context, mainly driven by the identity of the exon's splice sites, the conservation around them, and its exon/intron architecture. Thus, the splicing behavior of human exons can be reliably predicted based on basic RNA sequence elements. PMID:25805853

Examining the Potential for Agricultural Benefits from Pollinator Habitat at Solar Facilities in the United States.

PubMed

Walston, Leroy J; Mishra, Shruti K; Hartmann, Heidi M; Hlohowskyj, Ihor; McCall, James; Macknick, Jordan

2018-06-13

Of the many roles insects serve for ecosystem function, pollination is possibly the most important service directly linked to human well-being. However, land use changes have contributed to the decline of pollinators and their habitats. In agricultural landscapes that also support renewable energy developments such as utility-scale solar energy [USSE] facilities, opportunities may exist to conserve insect pollinators and locally restore their ecosystem services through the implementation of vegetation management approaches that aim to provide and maintain pollinator habitat at USSE facilities. As a first step toward understanding the potential agricultural benefits of solar-pollinator habitat, we identified areas of overlap between USSE facilities and surrounding pollinator-dependent crop types in the United States (U.S.). Using spatial data on solar energy developments and crop types across the U.S., and assuming a pollinator foraging distance of 1.5 km, we identified over 3,500 km 2 of agricultural land near existing and planned USSE facilities that may benefit from increased pollination services through the creation of pollinator habitat at the USSE facilities. The following five pollinator-dependent crop types accounted for over 90% of the agriculture near USSE facilities, and these could benefit most from the creation of pollinator habitat at existing and planned USSE facilities: soybeans, alfalfa, cotton, almonds, and citrus. We discuss how our results may be used to understand potential agro-economic implications of solar-pollinator habitat. Our results show that ecosystem service restoration through the creation of pollinator habitat could improve the sustainability of large-scale renewable energy developments in agricultural landscapes.

Graph theoretic analysis of structural connectivity across the spectrum of Alzheimer's disease: The importance of graph creation methods

PubMed Central

Phillips, David J.; McGlaughlin, Alec; Ruth, David; Jager, Leah R.; Soldan, Anja

2015-01-01

Graph theory is increasingly being used to study brain connectivity across the spectrum of Alzheimer's disease (AD), but prior findings have been inconsistent, likely reflecting methodological differences. We systematically investigated how methods of graph creation (i.e., type of correlation matrix and edge weighting) affect structural network properties and group differences. We estimated the structural connectivity of brain networks based on correlation maps of cortical thickness obtained from MRI. Four groups were compared: 126 cognitively normal older adults, 103 individuals with Mild Cognitive Impairment (MCI) who retained MCI status for at least 3 years (stable MCI), 108 individuals with MCI who progressed to AD-dementia within 3 years (progressive MCI), and 105 individuals with AD-dementia. Small-world measures of connectivity (characteristic path length and clustering coefficient) differed across groups, consistent with prior studies. Groups were best discriminated by the Randić index, which measures the degree to which highly connected nodes connect to other highly connected nodes. The Randić index differentiated the stable and progressive MCI groups, suggesting that it might be useful for tracking and predicting the progression of AD. Notably, however, the magnitude and direction of group differences in all three measures were dependent on the method of graph creation, indicating that it is crucial to take into account how graphs are constructed when interpreting differences across diagnostic groups and studies. The algebraic connectivity measures showed few group differences, independent of the method of graph construction, suggesting that global connectivity as it relates to node degree is not altered in early AD. PMID:25984446

Mobile VR in Education: From the Fringe to the Mainstream

ERIC Educational Resources Information Center

Cochrane, Thomas

2016-01-01

This paper explores the development of virtual reality (VR) use in education and the emergence of mobile VR based content creation and sharing as a platform for enabling learner-generated content and learner-generated contexts. The author argues that an ecology of resources that maps the user content creation and sharing affordances of mobile…

Co-Creation Learning Procedures: Comparing Interactive Language Lessons for Deaf and Hearing Students.

PubMed

Hosono, Naotsune; Inoue, Hiromitsu; Tomita, Yutaka

2017-01-01

This paper discusses co-creation learning procedures of second language lessons for deaf students, and sign language lessons by a deaf lecturer. The analyses focus on the learning procedure and resulting assessment, considering the disability. Through questionnaires ICT-based co-creative learning technologies are effective and efficient and promote spontaneous learning motivation goals.

Diversifying Assessment through Multimedia Creation in a Non-Technical Module: Reflections on the MAIK Project

ERIC Educational Resources Information Center

Cox, Andrew M.; Vasconcelos, Ana Cristina; Holdridge, Peter

2010-01-01

Creation of multimedia (MM) could be a valuable diversification of assessment methods within non-technical modules. The apparent popularity of sites based on user-generated video content such as YouTube and also of podcasting suggests that relevant skills and interest are becoming more mainstream. Translating book learned knowledge into visual…

The Creation of Task-Based Differentiated Learning Materials for Students with Learning Difficulties and/or Disabilities.

ERIC Educational Resources Information Center

Barker, Trevor; Jones, Sara; Britton, Carol; Messer, David

This paper describes Horizon, a European-funded project designed to increase employment opportunities for students with disabilities or learning difficulties. The project established a working cafe/restaurant (Cafe Horizon) in East London staffed by students. Part of the project involved the creation of multimedia units linked directly to Level 1…

The Role of Media/Video Production in Non-Media Disciplines: The Case of Health Promotion

ERIC Educational Resources Information Center

Shuldman, Mitch; Tajik, Mansoureh

2010-01-01

Media creation has been almost exclusively a domain of media and communication fields. Traditionally, non-media fields, such as public health and health promotion, do not typically include media creation courses. As media technologies continue to advance, however, opportunities arise for the development of new pedagogical models based on new…

ICBP90 Regulation of DNA Methylation, Histone Ubiquitination, and Tumor Suppressor Gene Expression in Breast Cancer Cells

DTIC Science & Technology

2011-07-01

type and mutant plants via chromatin immunoprecipitation (ChIP). Additionally, differences in centromere structure between wild-type and VIM1 RING...contexts. The proposed work is ongoing, and so far the major accomplishments include creation of relevant plant lines and development of in vitro assays...a comparative proteomics approach in wild-type plants and RING domain mutants (Months 1 - 18) This work is in early stages, with the main

Who is having a voice? Journalists' selection of sources in a creationism controversy in the UK press

NASA Astrophysics Data System (ADS)

Allgaier, Joachim

2011-06-01

Media accounts of reality have the potential to influence public opinion and decision making processes. Therefore who has and who does not have access to the media and can make their voice heard is a crucial question with serious political consequences. In this article it is investigated whether the speciality of journalists influences their source selection procedures. The coverage of science in schools is an interesting example, since it can be covered by specialized science or education correspondents, but also by general news reporters. A public controversy in the UK about the inclusion of creationism in a school is used to identify which types of sources were selected by various journalists. The focus is upon the selection of sources and whether journalists with different specialties consider various sources relevant and credible. A content analysis of articles, featuring this controversy, is combined with an analysis of correspondent's strategies for selecting sources based on interviews with them. The findings suggest that compared to journalists that specialize in education issues, science correspondents employ a narrower scope when seeking sources. This might have important consequences for the representation of views on science education in the media.

MSW-resonant fermion mixing during reheating

NASA Astrophysics Data System (ADS)

Kanai, Tsuneto; Tsujikawa, Shinji

2003-10-01

We study the dynamics of reheating in which an inflaton field couples two flavor fermions through Yukawa-couplings. When two fermions have a mixing term with a constant coupling, we show that the Mikheyev-Smirnov-Wolfenstein (MSW)-type resonance emerges due to a time-dependent background in addition to the standard fermion creation via parametric resonance. This MSW resonance not only alters the number densities of fermions generated by a preheating process but also can lead to the larger energy transfer from the inflaton to fermions. Our mechanism can provide additional source terms for the creation of superheavy fermions which may be relevant for the leptogenesis scenario.

Thermodynamics of cosmological matter creation

PubMed Central

Prigogine, I.; Geheniau, J.; Gunzig, E.; Nardone, P.

1988-01-01

A type of cosmological history that includes large-scale entropy production is proposed. These cosmologies are based on reinterpretation of the matter-energy stress tensor in Einstein's equations. This modifies the usual adiabatic energy conservation laws, thereby including irreversible matter creation. This creation corresponds to an irreversible energy flow from the gravitational field to the created matter constituents. This point of view results from consideration of the thermodynamics of open systems in the framework of cosmology. It is shown that the second law of thermodynamics requires that space-time transforms into matter, while the inverse transformation is forbidden. It appears that the usual initial singularity associated with the big bang is structurally unstable with respect to irreversible matter creation. The corresponding cosmological history therefore starts from an instability of the vacuum rather than from a singularity. This is exemplified in the framework of a simple phenomenological model that leads to a three-stage cosmology: the first drives the cosmological system from the initial instability to a de Sitter regime, and the last connects with the usual matter-radiation Robertson-Walker universe. Matter as well as entropy creation occurs during the first two stages, while the third involves the traditional cosmological evolution. A remarkable fact is that the de Sitter stage appears to be an attractor independent of the initial fluctuation. This is also the case for all the physical predictions involving the present Robertson-Walker universe. Most results obtained previously, in the framework of quantum field theory, can now be obtained on a macroscopic basis. It is shown that this description leads quite naturally to the introduction of primeval black holes as the intermediate stage between the Minkowski vacuum and the present matter-radiation universe. The instability at the origin of the universe is the result of fluctuations of the vacuum in which black holes act as membranes that stabilize these fluctuations. In short, black holes will be produced by and “inverse” Hawking radiation process and, once formed, will decompose into “real” matter through the usual Hawking radiation. In this way, the irreversible transformation of space-time into matter can be described as a phase separation between matter and gravitation in which black holes play the role of “critical nuclei.” PMID:16593986

Performance Assessment of Passive Hearing Protection Devices

DTIC Science & Technology

2014-10-24

ear ................................................ 9 Figure 11. Schematic of the set-up of the explosive charge for the creation of a shock wave...10 Table 1: Type and mass of explosive and distance between ATF and explosive for different peak pressure levels and A-durations...OF TABLES Table 1: Type and mass of explosive and distance between ATF and explosive for different peak pressure levels and A-durations

Synthesizing Biomolecule-based Boolean Logic Gates

PubMed Central

Miyamoto, Takafumi; Razavi, Shiva; DeRose, Robert; Inoue, Takanari

2012-01-01

One fascinating recent avenue of study in the field of synthetic biology is the creation of biomolecule-based computers. The main components of a computing device consist of an arithmetic logic unit, the control unit, memory, and the input and output devices. Boolean logic gates are at the core of the operational machinery of these parts, hence to make biocomputers a reality, biomolecular logic gates become a necessity. Indeed, with the advent of more sophisticated biological tools, both nucleic acid- and protein-based logic systems have been generated. These devices function in the context of either test tubes or living cells and yield highly specific outputs given a set of inputs. In this review, we discuss various types of biomolecular logic gates that have been synthesized, with particular emphasis on recent developments that promise increased complexity of logic gate circuitry, improved computational speed, and potential clinical applications. PMID:23526588

Synthesizing biomolecule-based Boolean logic gates.

PubMed

Miyamoto, Takafumi; Razavi, Shiva; DeRose, Robert; Inoue, Takanari

2013-02-15

One fascinating recent avenue of study in the field of synthetic biology is the creation of biomolecule-based computers. The main components of a computing device consist of an arithmetic logic unit, the control unit, memory, and the input and output devices. Boolean logic gates are at the core of the operational machinery of these parts, and hence to make biocomputers a reality, biomolecular logic gates become a necessity. Indeed, with the advent of more sophisticated biological tools, both nucleic acid- and protein-based logic systems have been generated. These devices function in the context of either test tubes or living cells and yield highly specific outputs given a set of inputs. In this review, we discuss various types of biomolecular logic gates that have been synthesized, with particular emphasis on recent developments that promise increased complexity of logic gate circuitry, improved computational speed, and potential clinical applications.

Standard Generalized Markup Language for self-defining structured reports.

PubMed

Kahn, C E

1999-01-01

Structured reporting is the process of using standardized data elements and predetermined data-entry formats to record observations. The Standard Generalized Markup Language (SGML; International Standards Organization (ISO) 8879:1986)--an open, internationally accepted standard for document interchange was used to encode medical observations acquired in an Internet-based structured reporting system. The resulting report is self-documenting: it includes a definition of its allowable data fields and values encoded as a report-specific SGML document type definition (DTD). The data-entry forms, DTD, and report document instances are based on report specifications written in a simple, SGML-based language designed for that purpose. Reporting concepts can be linked with those of external vocabularies such as the Unified Medical Language System (UMLS) Metathesaurus. The use of open standards such as SGML is an important step in the creation of open, universally comprehensible structured reports.

The instrumental genesis process in future primary teachers using Dynamic Geometry Software

NASA Astrophysics Data System (ADS)

Ruiz-López, Natalia

2018-05-01

This paper, which describes a study undertaken with pairs of future primary teachers using GeoGebra software to solve geometry problems, includes a brief literature review, the theoretical framework and methodology used. An analysis of the instrumental genesis process for a pair participating in the case study is also provided. This analysis addresses the techniques and types of dragging used, the obstacles to learning encountered, a description of the interaction between the pair and their interaction with the teacher, and the type of language used. Based on this analysis, possibilities and limitations of the instrumental genesis process are identified for the development of geometric competencies such as conjecture creation, property checking and problem researching. It is also suggested that the methodology used in the analysis of the problem solving process may be useful for those teachers and researchers who want to integrate Dynamic Geometry Software (DGS) in their classrooms.

"GARDEN OF CHILDHOOD" as an Innovative Approach to Training and Education of Children at Preschool Institutions

ERIC Educational Resources Information Center

Alekseeva, Larisa; Shkolyar, Luidmila; Savenkova, Luibov

2016-01-01

The authors reveal an innovative approach to training and education of preschool children. This approach is called "GARDEN OF CHILDHOOD". It is based on the idea that the development of the preschool child's personality should be joyous and free "cultural self-creation" in terms of the collective co-creation, where adults and…

The Creation of the "Hong Kong Visual Arts Education Web" and the Use of the Inquiry-Based Teaching Approach

ERIC Educational Resources Information Center

Sang, Anita Ng Heung

2009-01-01

This article describes a collaborative action research conducted by a lecturer and several primary school art teachers, who between 2001 and 2006 created the Visual Arts Education Web ("iii web") in Hong Kong. The creation of the "iii web" was accomplished through research that employed questionnaires, focus group discussions…

Promoting Creative Thinking and Expression of Science Concepts among Elementary Teacher Candidates through Science Content Movie Creation and Showcasing

ERIC Educational Resources Information Center

Hechter, Richard P.; Guy, Mark

2010-01-01

This article reports the phases of design and use of video editing technology as a medium for creatively expressing science content knowledge in an elementary science methods course. Teacher candidates communicated their understanding of standards-based core science concepts through the creation of original digital movies. The movies were assigned…

Money creation and circulation in a credit economy

NASA Astrophysics Data System (ADS)

Xiong, Wanting; Fu, Han; Wang, Yougui

2017-01-01

This paper presents a multi-agent model describing the main mechanisms of money creation and money circulation in a credit economy. Our special attention is paid to the role of debt in the two processes. With the agent-based modeling approach, macro phenomena are well founded in micro-based causalities. A hypothetical economy composed of a banking system and multiple traders is proposed. Instead of being a pure financial intermediary, the banking system is viewed as the center of money creation and an accelerator of money circulation. Agents finance their expenditures not only by their own savings but also through bank loans. Through mathematical calculations and numerical simulation, we identify the determinants of money multiplier and those of velocity of money. In contrast to the traditional money creation model, the money multiplier is determined not only by the behavior of borrowing but also by the behavior of repayment as well. The velocity of money is found to be influenced by both money-related factors such as the expenditure habits of agents with respect to their income and wealth and debt-related factors such as borrowing and repayment behaviors of debtors and the reserve requirements faced by banks.

Substantiation of International Nanomaterials Security Group Creation

NASA Astrophysics Data System (ADS)

Sosnov, A.; Sadovnikov, S.; Panfilov, S.; Magarshak, Yu.

Nanotechnology has achieved the status as one of the critical R&D area. Scientists use the unique properties of atomic and molecular assemblages built at the nanometer scale. The ability to manipulate the physical, chemical, and biological properties of molecules and particles affords to design agents with set up properties. But the technology allows creating not only useful agents. Possible accidental or deliberate creation of new nanoparticles (NPs) with dangerous properties is highly probable minor product of progress in the new area. The article briefly describes some pathways in development and implementation of NPs for medicinal and the similar purposes. Some of NPs can effective facilitate and mask transport of various agents in various environments. Possible creation of new dangerous NPs (e.g. conjugates based on combination of extensively use NPs and chemical, biological and radioactive agents) as well as creation of brand new NPs and nanodevices with unique properties needs creation of international multidiscipline community for security evaluation of nanomaterials and technologies. The community will forecast possible dangerous unexpectedness in the field of nanoscale materials and devices and suggests rational pathways for prevention of the threats.

The successes and challenges of open-source biopharmaceutical innovation.

PubMed

Allarakhia, Minna

2014-05-01

Increasingly, open-source-based alliances seek to provide broad access to data, research-based tools, preclinical samples and downstream compounds. The challenge is how to create value from open-source biopharmaceutical innovation. This value creation may occur via transparency and usage of data across the biopharmaceutical value chain as stakeholders move dynamically between open source and open innovation. In this article, several examples are used to trace the evolution of biopharmaceutical open-source initiatives. The article specifically discusses the technological challenges associated with the integration and standardization of big data; the human capacity development challenges associated with skill development around big data usage; and the data-material access challenge associated with data and material access and usage rights, particularly as the boundary between open source and open innovation becomes more fluid. It is the author's opinion that the assessment of when and how value creation will occur, through open-source biopharmaceutical innovation, is paramount. The key is to determine the metrics of value creation and the necessary technological, educational and legal frameworks to support the downstream outcomes of now big data-based open-source initiatives. The continued focus on the early-stage value creation is not advisable. Instead, it would be more advisable to adopt an approach where stakeholders transform open-source initiatives into open-source discovery, crowdsourcing and open product development partnerships on the same platform.

Polishing the craft of genetic diversity creation in directed evolution.

PubMed

Tee, Kang Lan; Wong, Tuck Seng

2013-12-01

Genetic diversity creation is a core technology in directed evolution where a high quality mutant library is crucial to its success. Owing to its importance, the technology in genetic diversity creation has seen rapid development over the years and its application has diversified into other fields of scientific research. The advances in molecular cloning and mutagenesis since 2008 were reviewed. Specifically, new cloning techniques were classified based on their principles of complementary overhangs, homologous sequences, overlapping PCR and megaprimers and the advantages, drawbacks and performances of these methods were highlighted. New mutagenesis methods developed for random mutagenesis, focused mutagenesis and DNA recombination were surveyed. The technical requirements of these methods and the mutational spectra were compared and discussed with references to commonly used techniques. The trends of mutant library preparation were summarised. Challenges in genetic diversity creation were discussed with emphases on creating "smart" libraries, controlling the mutagenesis spectrum and specific challenges in each group of mutagenesis methods. An outline of the wider applications of genetic diversity creation includes genome engineering, viral evolution, metagenomics and a study of protein functions. The review ends with an outlook for genetic diversity creation and the prospective developments that can have future impact in this field. © 2013. Published by Elsevier Inc. All rights reserved.

Percutaneous Creation of a Central Iliac Arteriovenous Anastomosis for the Treatment of Arterial Hypertension.

PubMed

Bertog, Stefan C; Sobotka, Nathan A; Sobotka, Paul A; Lobo, Melvin D; Sievert, Kolja; Vaskelyte, Laura; Sievert, Horst; Schmieder, Roland E

2018-03-19

Provision of a summary on the physiologic effects of arteriovenous fistula creation and description of previously published human data on the efficacy of a percutaneously implanted device creating an arteriovenous fistula. Though antihypertensive therapy is effective, some patient's blood pressure remains poorly controlled despite adherence to optimal medical therapy. Moreover, some patients are not compliant with recommended medical therapy due to side effects or personal decision. This has prompted exploration of alternative, device-based antihypertensive therapies including, among others, the percutaneous creation of an arteriovenous fistula. An arteriovenous fistula is accompanied by a number of favorable physiologic changes that may lower blood pressure. These physiologic changes, conduction of the procedure, and previously published human experience are summarized in this review article. The results of a recently published trial comparing arteriovenous fistula creation and standard antihypertensive therapy versus standard antihypertensive therapy alone are summarized. Creation of an arteriovenous fistula is accompanied by a significant blood pressure reduction likely related to a reduction in total arterial resistance, perhaps blood volume reduction, inhibition of the baroreceptor reflex, and release of natriuretic peptides. These findings foster further interest in studying the impact of an arteriovenous fistula and arterial blood pressure. The design of a large randomized trial comparing arteriovenous fistula creation to sham control is outlined.

Co-creation and Co-innovation in a Collaborative Networked Environment

NASA Astrophysics Data System (ADS)

Klen, Edmilson Rampazzo

Leveraged by the advances in communication and information Technologies, producers and consumers are developing a new behavior. Together with the new emerging collaborative manifestations this behavior may directly impact the way products are developed. This powerful combination indicates that consumers will be involved in a very early stage in product development processes supporting even more the creation and innovation of products. This new way of collaboration gives rise to a new collaborative networked environment based on co-creation and co-innovation. This work will present some evolutionary steps that point to the development of this environment where prosumer communities and virtual organizations interact and collaborate.

Particle creation and reheating in a braneworld inflationary scenario

NASA Astrophysics Data System (ADS)

Bilić, Neven; Domazet, Silvije; Djordjevic, Goran S.

2017-10-01

We study the cosmological particle creation in the tachyon inflation based on the D-brane dynamics in the Randall-Sundrum (RSII) model extended to include matter in the bulk. The presence of matter modifies the warp factor which results in two effects: a modification of the RSII cosmology and a modification of the tachyon potential. Besides, a string theory D-brane supports among other fields a U(1) gauge field reflecting open strings attached to the brane. We demonstrate how the interaction of the tachyon with the U(1) gauge field drives cosmological creation of massless particles and estimate the resulting reheating at the end of inflation.

Thought Spot: Co-Creating Mental Health Solutions with Post-Secondary Students.

PubMed

Wiljer, David; Johnson, Andrew; McDiarmid, Erica; Abi-Jaoude, Alexxa; Ferguson, Genevieve; Hollenberg, Elisa; van Heerwaarden, Nicole; Tripp, Tim; Law, Marcus

2017-01-01

It is difficult for the nearly 20% of Canadian 15- to 24-year olds reporting symptoms to seek the help they need within the current mental health system. Web-based and mobile health interventions are promising tools for reaching this group; having the capacity to reduce access-to-service barriers and engage youth in promoting their mental well-being. A three-phased, iterative, co-creation developmental approach was used to develop Thought Spot, a platform to better enable post-secondary students to seek mental health support. Co-creation activities included student development teams, hosting a hackathon, conducting focus groups and evidence-based workshops and student advisory groups. Evaluation results highlighted the need for greater role clarity and strategies for sustainable engagement in the co-creation process. Lessons learned are informing the project optimization phase and will be utilized to inform the design and implementation of an RCT, assessing impact on help seeking behaviour.

Frequency distributions from birth, death, and creation processes.

PubMed

Bartley, David L; Ogden, Trevor; Song, Ruiguang

2002-01-01

The time-dependent frequency distribution of groups of individuals versus group size was investigated within a continuum approximation, assuming a simplified individual growth, death and creation model. The analogy of the system to a physical fluid exhibiting both convection and diffusion was exploited in obtaining various solutions to the distribution equation. A general solution was approximated through the application of a Green's function. More specific exact solutions were also found to be useful. The solutions were continually checked against the continuum approximation through extensive simulation of the discrete system. Over limited ranges of group size, the frequency distributions were shown to closely exhibit a power-law dependence on group size, as found in many realizations of this type of system, ranging from colonies of mutated bacteria to the distribution of surnames in a given population. As an example, the modeled distributions were successfully fit to the distribution of surnames in several countries by adjusting the parameters specifying growth, death and creation rates.

Direct writing of room temperature and zero field skyrmion lattices by a scanning local magnetic field

NASA Astrophysics Data System (ADS)

Zhang, Senfu; Zhang, Junwei; Zhang, Qiang; Barton, Craig; Neu, Volker; Zhao, Yuelei; Hou, Zhipeng; Wen, Yan; Gong, Chen; Kazakova, Olga; Wang, Wenhong; Peng, Yong; Garanin, Dmitry A.; Chudnovsky, Eugene M.; Zhang, Xixiang

2018-03-01

Magnetic skyrmions are topologically protected nanoscale spin textures exhibiting fascinating physical behaviors. Recent observations of room temperature skyrmions in sputtered multilayer films are an important step towards their use in ultra-low power devices. Such practical applications prefer skyrmions to be stable at zero magnetic fields and room temperature. Here, we report the creation of skyrmion lattices in Pt/Co/Ta multilayers by a scanning local field using magnetic force microscopy tips. We also show that those newly created skyrmion lattices are stable at both room temperature and zero fields. Lorentz transmission electron microscopy measurements reveal that the skyrmions in our films are of Néel-type. To gain a deeper understanding of the mechanism behind the creation of a skyrmion lattice by the scanning of local fields, we perform micromagnetic simulations and find the experimental results to be in agreement with our simulation data. This study opens another avenue for the creation of skyrmion lattices in thin films.

Model-based engineering for medical-device software.

PubMed

Ray, Arnab; Jetley, Raoul; Jones, Paul L; Zhang, Yi

2010-01-01

This paper demonstrates the benefits of adopting model-based design techniques for engineering medical device software. By using a patient-controlled analgesic (PCA) infusion pump as a candidate medical device, the authors show how using models to capture design information allows for i) fast and efficient construction of executable device prototypes ii) creation of a standard, reusable baseline software architecture for a particular device family, iii) formal verification of the design against safety requirements, and iv) creation of a safety framework that reduces verification costs for future versions of the device software. 1.

Developmental trends in the process of constructing own- and other-race facial composites.

PubMed

Kehn, Andre; Renken, Maggie D; Gray, Jennifer M; Nunez, Narina L

2014-01-01

The current study examined developmental differences from the age of 5 to 18 in the creation process of own- and other-race facial composites. In addition, it considered how differences in the creation process affect similarity ratings. Participants created two composites (one own- and one other-race) from memory. The complexity of the composite creation process was recorded during Phase One. In Phase Two, a separate group of participants rated the composites for similarity to the corresponding target face. Results support the cross-race effect, developmental differences (based on composite creators) in similarity ratings, and the importance of the creation process for own- and other-race facial composites. Together, these findings suggest that as children get older the process through which they create facial composites becomes more complex and their ability to create facial composites improves. Increased complexity resulted in higher rated composites. Results are discussed from a psycho-legal perspective.

Goal Attribution toward Non-Human Objects during Infancy Predicts Imaginary Companion Status during Preschool Years.

PubMed

Moriguchi, Yusuke; Kanakogi, Yasuhiro; Todo, Naoya; Okumura, Yuko; Shinohara, Ikuko; Itakura, Shoji

2016-01-01

It has been shown that there is a significant relationship between children's mentalizing skills and creation of an imaginary companion (IC). Theorists have proposed that interaction with an IC may improve mentalizing skills, but it is also possible that children's mentalizing skills affect their creation of an IC. In this longitudinal study, we examined whether goal attribution in infants younger than 1 years old (Time 1) predicted their creation of ICs at 48 months old (Time 2). At Time 1, infants' goal attribution was measured in an action prediction experiment, where infants anticipated three types of action goals: (1) another person's goal-directed action (GH condition); (2) another person's non-goal-directed (BH condition); and (3) a mechanical claw's goal-directed action (MC condition). At Time 2, parents completed questionnaires assessing whether their children had ICs. The path analyses using Bayesian estimation revealed that infants' anticipation in the MC condition, but not in the GH and BH conditions, predicted their later IC status. These results indicate that infants' goal attributions to non-human agents may be a strong predictor of their later IC creation. Early mentalizing skills toward non-human objects may provide children with a basis for their engagement in imaginative play.

Independence.

ERIC Educational Resources Information Center

Stephenson, Margaret E.

2000-01-01

Discusses the four planes of development and the periods of creation and crystallization within each plane. Identifies the type of independence that should be achieved by the end of the first two planes of development. Maintains that it is through individual work on the environment that one achieves independence. (KB)

Enhanced external quantum efficiency in GaN-based vertical-type light-emitting diodes by localized surface plasmons

PubMed Central

Yao, Yung-Chi; Hwang, Jung-Min; Yang, Zu-Po; Haung, Jing-Yu; Lin, Chia-Ching; Shen, Wei-Chen; Chou, Chun-Yang; Wang, Mei-Tan; Huang, Chun-Ying; Chen, Ching-Yu; Tsai, Meng-Tsan; Lin, Tzu-Neng; Shen, Ji-Lin; Lee, Ya-Ju

2016-01-01

Enhancement of the external quantum efficiency of a GaN-based vertical-type light emitting diode (VLED) through the coupling of localized surface plasmon (LSP) resonance with the wave-guided mode light is studied. To achieve this experimentally, Ag nanoparticles (NPs), as the LSP resonant source, are drop-casted on the most top layer of waveguide channel, which is composed of hydrothermally synthesized ZnO nanorods capped on the top of GaN-based VLED. Enhanced light-output power and external quantum efficiency are observed, and the amount of enhancement remains steady with the increase of the injected currents. To understand the observations theoretically, the absorption spectra and the electric field distributions of the VLED with and without Ag NPs decorated on ZnO NRs are determined using the finite-difference time-domain (FDTD) method. The results prove that the observation of enhancement of the external quantum efficiency can be attributed to the creation of an extra escape channel for trapped light due to the coupling of the LSP with wave-guided mode light, by which the energy of wave-guided mode light can be transferred to the efficient light scattering center of the LSP. PMID:26935648

A fuzzy logic approach to modeling a vehicle crash test

NASA Astrophysics Data System (ADS)

Pawlus, Witold; Karimi, Hamid Reza; Robbersmyr, Kjell G.

2013-03-01

This paper presents an application of fuzzy approach to vehicle crash modeling. A typical vehicle to pole collision is described and kinematics of a car involved in this type of crash event is thoroughly characterized. The basics of fuzzy set theory and modeling principles based on fuzzy logic approach are presented. In particular, exceptional attention is paid to explain the methodology of creation of a fuzzy model of a vehicle collision. Furthermore, the simulation results are presented and compared to the original vehicle's kinematics. It is concluded which factors have influence on the accuracy of the fuzzy model's output and how they can be adjusted to improve the model's fidelity.

The Genetic Privacy Act and commentary

DOE Office of Scientific and Technical Information (OSTI.GOV)

Annas, G.J.; Glantz, L.H.; Roche, P.A.

1995-02-28

The Genetic Privacy Act is a proposal for federal legislation. The Act is based on the premise that genetic information is different from other types of personal information in ways that require special protection. Therefore, to effectively protect genetic privacy unauthorized collection and analysis of individually identifiable DNA must be prohibited. As a result, the premise of the Act is that no stranger should have or control identifiable DNA samples or genetic information about an individual unless that individual specifically authorizes the collection of DNA samples for the purpose of genetic analysis, authorized the creation of that private information, andmore » has access to and control over the dissemination of that information.« less

The Ethnic Factor in the Soviet Armed Forces. The Muslim Dimension

DTIC Science & Technology

1991-01-01

Muslim conscripts into effective soldiers. The types of problems that a Muslim conscript presents for the Soviet military can be narrowed to two categories ... categories : ability and reliability. ETHNICITY AND DEMOGRAPHICS The major Soviet Muslim ethnic groups are creations of the Soviet regime, dating back to...avoid such embarrassments in the future. viii SOVIET MILITARY REFORM The predominantly coercive type of compliance previously used by the Soviet military

Examining the Potential for Agricultural Benefits from Pollinator Habitat at Solar Facilities in the United States

DOE Office of Scientific and Technical Information (OSTI.GOV)

McCall, James D; Macknick, Jordan E; Walston, Leroy J.

Of the many roles insects serve for ecosystem function, pollination is possibly the most important service directly linked to human well-being. However, land use changes have contributed to the decline of pollinators and their habitats. In agricultural landscapes that also support renewable energy developments such as utility-scale solar energy [USSE] facilities, opportunities may exist to conserve insect pollinators and locally restore their ecosystem services through the implementation of vegetation management approaches that aim to provide and maintain pollinator habitat at USSE facilities. As a first step toward understanding the potential agricultural benefits of solar-pollinator habitat, we identified areas of overlapmore » between USSE facilities and surrounding pollinator-dependent crop types in the United States (U.S.). Using spatial data on solar energy developments and crop types across the U.S., and assuming a pollinator foraging distance of 1.5 km, we identified over 3,500 km2 of agricultural land near existing and planned USSE facilities that may benefit from increased pollination services through the creation of pollinator habitat at the USSE facilities. The following five pollinator-dependent crop types accounted for over 90% of the agriculture near USSE facilities, and these could benefit most from the creation of pollinator habitat at existing and planned USSE facilities: soybeans, alfalfa, cotton, almonds, and citrus. We discuss how our results may be used to understand potential agro-economic implications of solar-pollinator habitat. Our results show that ecosystem service restoration through the creation of pollinator habitat could improve the sustainability of large-scale renewable energy developments in agricultural landscapes.« less

Direct Job Creation in the Public Sector. Evaluation of National Experience in Canada, Denmark, Norway, United Kingdom, United States.

ERIC Educational Resources Information Center

Organisation for Economic Cooperation and Development, Paris (France).

This report examines selected public sector direct job creation schemes that were in operation in 1977-1978 in Canada, Denmark, Norway, the United Kingdom, and the United States. Based on responses to a questionnaire and discussions with officials in the five countries, the information presented in the report is not intended to evaluate any one…

What's the fire danger now? Linking fuel inventories with atmospheric data

Treesearch

Christopher W. Woodall; Joseph J. Charney; Greg C. Liknes; Brian E. Potter

2005-01-01

The combination of forest fuel maps with real-time atmospheric data may enable the creation of more dynamic and comprehensive assessments of fire danger. The goal of this study was to combine fuel maps, based on data from the Forest Inventory and Analysis (FIA) program of the USDA Forest Service, with real-time atmospheric data for the creation of a more dynamic index...

nmsBuilder: Freeware to create subject-specific musculoskeletal models for OpenSim.

PubMed

Valente, Giordano; Crimi, Gianluigi; Vanella, Nicola; Schileo, Enrico; Taddei, Fulvia

2017-12-01

Musculoskeletal modeling and simulations of movement have been increasingly used in orthopedic and neurological scenarios, with increased attention to subject-specific applications. In general, musculoskeletal modeling applications have been facilitated by the development of dedicated software tools; however, subject-specific studies have been limited also by time-consuming modeling workflows and high skilled expertise required. In addition, no reference tools exist to standardize the process of musculoskeletal model creation and make it more efficient. Here we present a freely available software application, nmsBuilder 2.0, to create musculoskeletal models in the file format of OpenSim, a widely-used open-source platform for musculoskeletal modeling and simulation. nmsBuilder 2.0 is the result of a major refactoring of a previous implementation that moved a first step toward an efficient workflow for subject-specific model creation. nmsBuilder includes a graphical user interface that provides access to all functionalities, based on a framework for computer-aided medicine written in C++. The operations implemented can be used in a workflow to create OpenSim musculoskeletal models from 3D surfaces. A first step includes data processing to create supporting objects necessary to create models, e.g. surfaces, anatomical landmarks, reference systems; and a second step includes the creation of OpenSim objects, e.g. bodies, joints, muscles, and the corresponding model. We present a case study using nmsBuilder 2.0: the creation of an MRI-based musculoskeletal model of the lower limb. The model included four rigid bodies, five degrees of freedom and 43 musculotendon actuators, and was created from 3D surfaces of the segmented images of a healthy subject through the modeling workflow implemented in the software application. We have presented nmsBuilder 2.0 for the creation of musculoskeletal OpenSim models from image-based data, and made it freely available via nmsbuilder.org. This application provides an efficient workflow for model creation and helps standardize the process. We hope this would help promote personalized applications in musculoskeletal biomechanics, including larger sample size studies, and might also represent a basis for future developments for specific applications. Copyright © 2017 Elsevier B.V. All rights reserved.

Myth and reality in the rural health service crisis: facing up to community responsibilities.

PubMed

Amundson, B

1993-01-01

Rural communities, rural advocacy organizations, and policy makers persist in perpetuating two serious but related misconceptions, namely: (1) The continuing deterioration of health services in most rural communities is primarily the result of forces and factors outside of the communities themselves, and (2) the solution to reverse this deterioration will come mainly from changes in reimbursement and other types of public policy initiatives. Overemphasis on the role of external factors has created a serious imbalance in programs, resources, and policy efforts, including those supported by the NRHA, resulting in inadequate national efforts and resources to foster community-based solutions. Suggested solutions include: (1) application by communities of a proven set of principles for organizing and developing local health services, and (2) creation of a national network to promote such community-based solutions.

Flow dynamics and salt transport in a coastal aquifer driven by a stratified saltwater body: Lab experiment and numerical modeling

NASA Astrophysics Data System (ADS)

Oz, Imri; Shalev, Eyal; Yechieli, Yoseph; Gavrieli, Ittai; Gvirtzman, Haim

2014-04-01

This paper examines the transient development and the steady-state configuration of groundwater within a coastal aquifer adjacent to a stratified saltwater body. Such systems consist of three different water types: the regional fresh groundwater, and low and high salinity brines forming the upper and lower water layers of the stratified water body, respectively. The dynamics, location and the geometry of the interfaces and the density-driven circulation flows that develop in the aquifer are examined using laboratory experiments and numerical modeling at the same scale. The results show that the transient intrusion of the different water bodies into the aquifer takes place at different rates, and that the locations of the interfaces between them change with time, before reaching steady-state. Under steady-state conditions both the model and the experiments show the existence of three interfaces between the three water types. The numerical model, which is calibrated against the salinity distribution and groundwater discharge rate in the laboratory experiments, allows the quantification of the flow rates and flow patterns within the aquifer. These flow patterns, which cannot be derived from laboratory experiments, show the transient development of three circulation cells which are confined between the three interfaces. These results confirm the hypothesis that has been previously suggested based solely on a steady-state numerical modeling defined by a conceptual understanding. Parametric analysis shows that the creation of three circulation cells and three interfaces is limited to certain conditions and defines the ranges for the creation of this unique system.

Sensing for HOV/HOT lanes enforcement : final report.

DOT National Transportation Integrated Search

2017-02-01

The use and creation of combined high-occupancy vehicle/high-occupancy toll (HOV/HOT Lanes) have become : more common in urban areas since all types of road users can take advantage of the lane either as a highoccupancy : vehicle or opting in to pay ...

From Where You Sit.

ERIC Educational Resources Information Center

Kennedy, Mike

2001-01-01

Explains how furniture selection for residence halls depends on the space available, the function it is intended to serve, and the types of students who live there. Discusses the creation of a home-like atmosphere, including instituting regulations that let students supply some of their own furniture. (GR)

75 FR 81239 - Proposed Collection; Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-27

... civilian job creation and type of redevelopment at the former military installations. The respondents to... generate jobs as military activity diminishes and to serve as a clearinghouse for reuse data. Affected... DEPARTMENT OF DEFENSE Office of the Secretary [Docket ID DOD-2010-OS-0170] Proposed Collection...

Simulated Breeding

NASA Astrophysics Data System (ADS)

Unemi, Tatsuo

This chapter describes a basic framework of simulated breeding, a type of interactive evolutionary computing to breed artifacts, whose origin is Blind Watchmaker by Dawkins. These methods make it easy for humans to design a complex object adapted to his/her subjective criteria, just similarly to agricultural products we have been developing over thousands of years. Starting from randomly initialized genome, the solution candidates are improved through several generations with artificial selection. The graphical user interface helps the process of breeding with techniques of multifield user interface and partial breeding. The former improves the diversity of individuals that prevents being trapped at local optimum. The latter makes it possible for the user to fix features he/she already satisfied. These methods were examined through artistic applications by the author: SBART for graphics art and SBEAT for music. Combining with a direct genome editor and exportation to another graphical or musical tool on the computer, they can be powerful tools for artistic creation. These systems may contribute to the creation of a type of new culture.

The audiovisual structure of onomatopoeias: An intrusion of real-world physics in lexical creation.

PubMed

Taitz, Alan; Assaneo, M Florencia; Elisei, Natalia; Trípodi, Mónica; Cohen, Laurent; Sitt, Jacobo D; Trevisan, Marcos A

2018-01-01

Sound-symbolic word classes are found in different cultures and languages worldwide. These words are continuously produced to code complex information about events. Here we explore the capacity of creative language to transport complex multisensory information in a controlled experiment, where our participants improvised onomatopoeias from noisy moving objects in audio, visual and audiovisual formats. We found that consonants communicate movement types (slide, hit or ring) mainly through the manner of articulation in the vocal tract. Vowels communicate shapes in visual stimuli (spiky or rounded) and sound frequencies in auditory stimuli through the configuration of the lips and tongue. A machine learning model was trained to classify movement types and used to validate generalizations of our results across formats. We implemented the classifier with a list of cross-linguistic onomatopoeias simple actions were correctly classified, while different aspects were selected to build onomatopoeias of complex actions. These results show how the different aspects of complex sensory information are coded and how they interact in the creation of novel onomatopoeias.

ALR - Laser altimeter for the ASTER deep space mission. Simulated operation above a surface with crater

NASA Astrophysics Data System (ADS)

de Brum, A. G. V.; da Cruz, F. C.; Hetem, A., Jr.

2015-10-01

To assist in the investigation of the triple asteroid system 2001-SN263, the deep space mission ASTER will carry onboard a laser altimeter. The instrument was named ALR and its development is now in progress. In order to help in the instrument design, with a view to the creation of software to control the instrument, a package of computer programs was produced to simulate the operation of a pulsed laser altimeter with operating principle based on the measurement of the time of flight of the travelling pulse. This software Simulator was called ALR_Sim, and the results obtained with its use represent what should be expected as return signal when laser pulses are fired toward a target, reflect on it and return to be detected by the instrument. The program was successfully tested with regard to some of the most common situations expected. It constitutes now the main workbench dedicated to the creation and testing of control software to embark in the ALR. In addition, the Simulator constitutes also an important tool to assist the creation of software to be used on Earth, in the processing and analysis of the data received from the instrument. This work presents the results obtained in the special case which involves the modeling of a surface with crater, along with the simulation of the instrument operation above this type of terrain. This study points out that the comparison of the wave form obtained as return signal after reflection of the laser pulse on the surface of the crater with the expected return signal in the case of a flat and homogeneous surface is a useful method that can be applied for terrain details extraction.

Investigating Deformation and Mesoscale Void Creation in HMX Based Composites using Tomography Based Grain Scale Finite Element Modeling

NASA Astrophysics Data System (ADS)

Walters, David J.; Luscher, Darby J.; Manner, Virginia; Yeager, John D.; Patterson, Brian M.

2017-06-01

The microstructure of plastic bonded explosives (PBXs) significantly affects their macroscale mechanical characteristics. Imaging and modeling of the mesoscale constituents allows for a detailed examination of the deformation of mechanically loaded PBXs. In this study, explosive composites, formulated with HMX crystals and various HTPB based polymer binders have been imaged using micro Computed Tomography (μCT). Cohesive parameters for simulation of the crystal/binder interface are determined by comparing numerical and experimental results of the delamination of a polymer bound bi-crystal system. Similarly, polycrystalline samples are discretized into a finite element mesh using the mesoscale geometry captured by in-situ μCT imaging. Experimentally, increasing the stiffness of the HTPB binder in the polycrystalline system resulted in a transition from ductile flow with little crystal/binder delamination to brittle behavior with increased void creation along the interfaces. Simulating the macroscale compression of these samples demonstrates the effects that the mesoscale geometry, cohesive properties, and binder stiffness have on the creation and distribution of interfacial voids. Understanding void nucleation is critical for modeling damage in these complex materials.

Extraction of Multilayered Social Networks from Activity Data

PubMed Central

Bródka, Piotr; Kazienko, Przemysław; Gaworecki, Jarosław

2014-01-01

The data gathered in all kinds of web-based systems, which enable users to interact with each other, provides an opportunity to extract social networks that consist of people and relationships between them. The emerging structures are very complex due to the number and type of discovered connections. In web-based systems, the characteristic element of each interaction between users is that there is always an object that serves as a communication medium. This can be, for example, an e-mail sent from one user to another or post at the forum authored by one user and commented on by others. Based on these objects and activities that users perform towards them, different kinds of relationships can be identified and extracted. Additional challenge arises from the fact that hierarchies can exist between objects; for example, a forum consists of one or more groups of topics, and each of them contains topics that finally include posts. In this paper, we propose a new method for creation of multilayered social network based on the data about users activities towards different types of objects between which the hierarchy exists. Due to the flattening, preprocessing procedure of new layers and new relationships in the multilayered social network can be identified and analysed. PMID:25105159

Three-Dimensional Printing and Cell Therapy for Wound Repair.

PubMed

van Kogelenberg, Sylvia; Yue, Zhilian; Dinoro, Jeremy N; Baker, Christopher S; Wallace, Gordon G

2018-05-01

Significance: Skin tissue damage is a major challenge and a burden on healthcare systems, from burns and other trauma to diabetes and vascular disease. Although the biological complexities are relatively well understood, appropriate repair mechanisms are scarce. Three-dimensional bioprinting is a layer-based approach to regenerative medicine, whereby cells and cell-based materials can be dispensed in fine spatial arrangements to mimic native tissue. Recent Advances: Various bioprinting techniques have been employed in wound repair-based skin tissue engineering, from laser-induced forward transfer to extrusion-based methods, and with the investigation of the benefits and shortcomings of each, with emphasis on biological compatibility and cell proliferation, migration, and vitality. Critical issues: Development of appropriate biological inks and the vascularization of newly developed tissues remain a challenge within the field of skin tissue engineering. Future Directions: Progress within bioprinting requires close interactions between material scientists, tissue engineers, and clinicians. Microvascularization, integration of multiple cell types, and skin appendages will be essential for creation of complex skin tissue constructs.

Analogue of cosmological particle creation in an ion trap.

PubMed

Schützhold, Ralf; Uhlmann, Michael; Petersen, Lutz; Schmitz, Hector; Friedenauer, Axel; Schätz, Tobias

2007-11-16

We study phonons in a dynamical chain of ions confined by a trap with a time-dependent (axial) potential strength and demonstrate that they behave in the same way as quantum fields in an expanding or contracting Universe. Based on this analogy, we present a scheme for the detection of the analogue of cosmological particle creation which should be feasible with present day technology. In order to test the quantum nature of the particle creation mechanism and to distinguish it from classical effects such as heating, we propose to measure the two-phonon amplitude via the 2nd red sideband transition and to compare it with the one-phonon amplitude (1st red sideband).

Strain-controlled skyrmion creation and propagation in ferroelectric/ferromagnetic hybrid wires

NASA Astrophysics Data System (ADS)

Li, Zhi; Zhang, Youguang; Huang, Yangqi; Wang, Chengxiang; Zhang, Xichao; Liu, Yan; Zhou, Yan; Kang, Wang; Koli, Shradha Chandrashekhar; Lei, Na

2018-06-01

The control of magnetic skyrmion creation and pinning through strain is studied by micromagnetic simulations. A single stable skyrmion can be created by a vertical strain pulse on Pd/Fe/Ir hybrid structure on Pb(Zr1-xTix)O3 nanowire with -1.8 V pulse voltage from 1.2 ns to 2.0 ns. Then the skyrmion is pinned by the vertical strain independent of the polarity during its propagation in the wire driven by the current. The proposed device integrates strain-controlled skyrmion creation and pinning in a single nanowire structure, which would open a new route for skyrmion-based memory and logic devices with ultra-low power consumption.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jesus, J.F.; Pereira, S.H., E-mail: jfjesus@itapeva.unesp.br, E-mail: shpereira@gmail.com

In this work the results from the quantum process of matter creation have been used in order to constrain the mass of the dark matter particles in an accelerated Cold Dark Matter model (Creation Cold Dark Matter, CCDM). In order to take into account a back reaction effect due to the particle creation phenomenon, it has been assumed a small deviation ε for the scale factor in the matter dominated era of the form t{sup 2/3+ε}. Based on recent H(z) data, the best fit values for the mass of dark matter created particles and the ε parameter have been foundmore » as m = 1.6× 10{sup 3} GeV, restricted to a 68.3% c.l. interval of 1.5 < m < 6.3× 10{sup 7}) GeV and ε = -0.250{sup +0.15}{sub -0.096} at 68.3% c.l. For these best fit values the model correctly recovers a transition from decelerated to accelerated expansion and admits a positive creation rate near the present era. Contrary to recent works in CCDM models where the creation rate was phenomenologically derived, here we have used a quantum mechanical result for the creation rate of real massive scalar particles, given a self consistent justification for the physical process. This method also indicates a possible solution to the so called ''dark degeneracy'', where one can not distinguish if it is the quantum vacuum contribution or quantum particle creation which accelerates the Universe expansion.« less

Promoting Knowledge Creation Discourse in an Asian Primary Five Classroom: Results from an inquiry into life cycles

NASA Astrophysics Data System (ADS)

van Aalst, Jan; Sioux Truong, Mya

2011-03-01

The phrase 'knowledge creation' refers to the practices by which a community advances its collective knowledge. Experience with a model of knowledge creation could help students to learn about the nature of science. This research examined how much progress a teacher and 16 Primary Five (Grade 4) students in the International Baccalaureate Primary Years Programme could make towards the discourse needed for Bereiter and Scardamalia's model of knowledge creation. The study consisted of two phases: a five-month period focusing on the development of the classroom ethos and skills needed for this model (Phase 1), followed by a two-month inquiry into life cycles (Phase 2). In Phase 1, we examined the classroom practices that are thought to support knowledge creation and the early experiences of the students with a web-based inquiry environment, Knowledge Forum®. In Phase 2, we conducted a summative evaluation of the students' work in Knowledge Forum in the light of the model. The data sources included classroom video recordings, artefacts of the in-class work, the Knowledge Forum database, a science content test, questionnaires, and interviews. The findings indicate that the students made substantial progress towards the knowledge creation discourse, particularly regarding the social structure of this kind of discourse and, to a lesser extent, its idea-centred nature. They also made acceptable advances in scientific knowledge and appeared to enjoy this way of learning. The study provides one of the first accounts in the literature of how a teacher new to the knowledge creation model enacted it in an Asian primary classroom.

Speeding up ontology creation of scientific terms

NASA Astrophysics Data System (ADS)

Bermudez, L. E.; Graybeal, J.

2005-12-01

An ontology is a formal specification of a controlled vocabulary. Ontologies are composed of classes (similar to categories), individuals (members of classes) and properties (attributes of the individuals). Having vocabularies expressed in a formal specification like the Web Ontology Language (OWL) enables interoperability due to the comprehensiveness of OWL by software programs. Two main non-inclusive strategies exist when constructing an ontology: an up-down approach and a bottom-up approach. The former one is directed towards the creation of top classes first (main concepts) and then finding the required subclasses and individuals. The later approach starts from the individuals and then finds similar properties promoting the creation of classes. At the Marine Metadata Interoperability (MMI) Initiative we used a bottom-up approach to create ontologies from simple-vocabularies (those that are not expressed in a conceptual way). We found that the vocabularies were available in different formats (relational data bases, plain files, HTML, XML, PDF) and sometimes were composed of thousands of terms, making the ontology creation process a very time consuming activity. To expedite the conversion process we created a tool VOC2OWL that takes a vocabulary in a table like structure (CSV or TAB format) and a conversion-property file to create automatically an ontology. We identified two basic structures of simple-vocabularies: Flat vocabularies (e.g., phone directory) and hierarchical vocabularies (e.g., taxonomies). The property file defines a list of attributes for the conversion process for each structure type. The attributes included metadata information (title, description, subject, contributor, urlForMoreInformation) and conversion flags (treatAsHierarchy, generateAutoIds) and other conversion information needed to create the ontology (columnForPrimaryClass, columnsToCreateClassesFrom, fileIn, fileOut, namespace, format). We created more than 50 ontologies and generated more than 250,000 statements (or triples). The previous ontologies allowed domain experts to create 800 relations allowing to infer 2200 more relations among different vocabularies in the MMI workshop "Advancing Domain Vocabularies" held in Boulder Aug, 2005.

ModFossa: A library for modeling ion channels using Python.

PubMed

Ferneyhough, Gareth B; Thibealut, Corey M; Dascalu, Sergiu M; Harris, Frederick C

2016-06-01

The creation and simulation of ion channel models using continuous-time Markov processes is a powerful and well-used tool in the field of electrophysiology and ion channel research. While several software packages exist for the purpose of ion channel modeling, most are GUI based, and none are available as a Python library. In an attempt to provide an easy-to-use, yet powerful Markov model-based ion channel simulator, we have developed ModFossa, a Python library supporting easy model creation and stimulus definition, complete with a fast numerical solver, and attractive vector graphics plotting.

Efficient creation of multipartite entanglement in flux qubits.

PubMed

Ferber, J; Wilhelm, F K

2010-07-09

We investigate three superconducting flux qubits coupled in a loop. In this setup, tripartite entanglement can be created in a natural, controllable, and stable way. Both generic kinds of tripartite entanglement--the W type as well as the GHZ type entanglement--can be identified among the eigenstates. We also discuss the violation of Bell inequalities in this system and show the impact of a limited measurement fidelity on the detection of entanglement and quantum nonlocality.

Checkpoint triggering in a computer system

DOEpatents

Cher, Chen-Yong

2016-09-06

According to an aspect, a method for triggering creation of a checkpoint in a computer system includes executing a task in a processing node of the computer system and determining whether it is time to read a monitor associated with a metric of the task. The monitor is read to determine a value of the metric based on determining that it is time to read the monitor. A threshold for triggering creation of the checkpoint is determined based on the value of the metric. Based on determining that the value of the metric has crossed the threshold, the checkpoint including state data of the task is created to enable restarting execution of the task upon a restart operation.

Making the Most of MASINT and Advanced Geospatial Intelligence

DTIC Science & Technology

2012-04-10

mining contracts and new job creation that ultimately supports economic development. This 22 type of forensic level analysis can make MASINT an...and Technology, ed. John D. Bossler (London: Taylor and Francis, 2002), 305 17 Jian Guo Liu and Philippa J. Mason, Essential Image Processing and

Job Loss and Infrastructure Job Creation Spending During the Recession

DTIC Science & Technology

2010-05-26

the clay product and refractory manufacturing industry used by the construction industry to erect residential buildings. The output requirements from...a particular point in time. The total employment requirement associated with a given type of final demand (e.g., a water reuse program) is the

Wear of enamel and veneering ceramics after laboratory and chairside finishing procedures.

PubMed

Magne, P; Oh, W S; Pintado, M R; DeLong, R

1999-12-01

This in vitro study compared the wear of enamel against 3 types of ceramics with high esthetic potential (designed for layering techniques): feldspathic porcelain (Creation), aluminous porcelain (Vitadur alpha), and low-fusing glass (Duceram-LFC). Laboratory finishing (glazing/polishing) and chairside polishing with a Dialite kit were simulated to compare their respective effects on wear. Tooth-material specimen pairs were placed in an artificial mouth using closed-loop servohydraulics. Constant masticatory parameters (13.5 N occlusal force, 0.62 mm lateral excursion; 0.23 second cuspal contact time) were maintained for 300, 000 cycles at a rate of 4 Hz. The occlusal surface of each pair was mapped and digitally recorded before and after each masticatory test. Quantitative changes were measured in terms of depth and volume of wear. Quantitative wear characteristics were assessed by SEM. Significant differences were observed (2-factor ANOVA, P <.05). Duceram-LFC generated increased volume loss of enamel (0.197 mm(3)) compared with Creation (0.135 mm(3)) and Vitadur alpha (0.153 mm(3)). Creation exhibited the lowest ceramic wear and lowest combined volume loss (0.260 mm(3); the sum of the data for enamel and the opposing material) compared with Duceram-LFC (0.363 mm(3)) and Vitadur alpha (0.333 mm(3)). The most significant differences among materials were observed in volume loss, not in depth of wear. For all 3 ceramic systems, qualitative SEM evaluation revealed an abrasive type of wear. Wear characteristics of chairside polished specimens were similar to those of laboratory finished specimens (glazed and polished). Duceram-LFC was the most abrasive ceramic for the antagonistic tooth. Creation ceramic was the least abrasive material and most resistant to wear. Defects, brittleness, and the possibly insufficient toughness of LFC may explain its increased abrasiveness. Laboratory and chairside finishing procedures generated similar results.

The OMI Aerosol Absorption Product: An A-train application

NASA Astrophysics Data System (ADS)

Torres, O.; Jethva, H. T.; Ahn, C.

2017-12-01

Because of the uniquely large sensitivity of satellite-measured near-UV radiances to absorption by desert dust, carbonaceous and volcanic ash aerosols, observations by a variety of UV-capable sensors have been routinely used over the last forty years in both qualitative and quantitative applications for estimating the absorption properties of these aerosol types. In this presentation we will discuss a multi-sensor application involving observations from A-train sensors OMI, AIRS and CALIOP for the creation of a 13-year record of aerosol optical depth (AOD) and single scattering albedo (SSA). Determination of aerosol type, in terms of particle size distribution and refractive index, is an important algorithmic step that requires using external information. AIRS CO measurements are used as carbonaceous aerosols tracer to differentiate this aerosol type from desert dust. On the other hand, the height of the absorbing aerosol layer, an important parameter in UV aerosol retrievals, is prescribed using a CALIOP-based climatology. The combined use of these observations in the developments of the OMI long-term AOD/SSA record will be discussed along with an evaluation of retrieval results using independent observations.

Preferential access to genetic information from endogenous hominin ancient DNA and accurate quantitative SNP-typing via SPEX

PubMed Central

Brotherton, Paul; Sanchez, Juan J.; Cooper, Alan; Endicott, Phillip

2010-01-01

The analysis of targeted genetic loci from ancient, forensic and clinical samples is usually built upon polymerase chain reaction (PCR)-generated sequence data. However, many studies have shown that PCR amplification from poor-quality DNA templates can create sequence artefacts at significant levels. With hominin (human and other hominid) samples, the pervasive presence of highly PCR-amplifiable human DNA contaminants in the vast majority of samples can lead to the creation of recombinant hybrids and other non-authentic artefacts. The resulting PCR-generated sequences can then be difficult, if not impossible, to authenticate. In contrast, single primer extension (SPEX)-based approaches can genotype single nucleotide polymorphisms from ancient fragments of DNA as accurately as modern DNA. A single SPEX-type assay can amplify just one of the duplex DNA strands at target loci and generate a multi-fold depth-of-coverage, with non-authentic recombinant hybrids reduced to undetectable levels. Crucially, SPEX-type approaches can preferentially access genetic information from damaged and degraded endogenous ancient DNA templates over modern human DNA contaminants. The development of SPEX-type assays offers the potential for highly accurate, quantitative genotyping from ancient hominin samples. PMID:19864251

West Java Snack Mapping based on Snack Types, Main Ingredients, and Processing Techniques

NASA Astrophysics Data System (ADS)

Nurani, A. S.; Subekti, S.; Ana

2016-04-01

The research was motivated by lack of literature on archipelago snack especially from West Java. It aims to explore the snack types, the processing techniques, and the main ingredients by planning a learning material on archipelago cake especially from West Java. The research methods used are descriptive observations and interviews. The samples were randomly chosen from all regions in West Java. The findings show the identification of traditional snack from West java including: 1. snack types which are similar in all regions as research sample namely: opak, rangginang, nagasari, aliagrem, cuhcur, keripik, semprong, wajit, dodol, kecimpring, combro, tape ketan, and surabi. The typical snack types involve burayot (Garut), simping kaum (Purwakarta), surabi hejo (Karawang), papais cisaat (Subang), Papais moyong, opak bakar (Kuningan), opak oded, ranggesing (Sumedang), gapit, tapel (Cirebon), gulampo, kue aci (Tasikmalaya), wajit cililin, gurilem (West Bandung), and borondong (Bandung District); 2. various processing techniques namely: steaming, boiling, frying, caramelizing, baking, grilling, roaster, sugaring; 3. various main ingredients namely rice, local glutinous rice, rice flour, glutinous rice flour, starch, wheat flour, hunkue flour, cassava, sweet potato, banana, nuts, and corn; 4. snack classification in West Java namely (1) traditional snack, (2) creation-snack, (3) modification-snack, (4) outside influence-snack.

Conceptualization of an R&D Based Learning-to-Innovate Model for Science Education

NASA Astrophysics Data System (ADS)

Lai, Oiki Sylvia

The purpose of this research was to conceptualize an R & D based learning-to-innovate (LTI) model. The problem to be addressed was the lack of a theoretical L TI model, which would inform science pedagogy. The absorptive capacity (ACAP) lens was adopted to untangle the R & D LTI phenomenon into four learning processes: problem-solving via knowledge acquisition, incremental improvement via knowledge participation, scientific discovery via knowledge creation, and product design via knowledge productivity. The four knowledge factors were the latent factors and each factor had seven manifest elements as measured variables. The key objectives of the non experimental quantitative survey were to measure the relative importance of the identified elements and to explore the underlining structure of the variables. A questionnaire had been prepared, and was administered to more than 155 R & D professionals from four sectors - business, academic, government, and nonprofit. The results showed that every identified element was important to the R & D professionals, in terms of improving the related type of innovation. The most important elements were highlighted to serve as building blocks for elaboration. In search for patterns of the data matrix, exploratory factor analysis (EF A) was performed. Principal component analysis was the first phase of EF A to extract factors; while maximum likelihood estimation (MLE) was used to estimate the model. EF A yielded the finding of two aspects in each kind of knowledge. Logical names were assigned to represent the nature of the subsets: problem and knowledge under knowledge acquisition, planning and participation under knowledge participation, exploration and discovery under knowledge creation, and construction and invention under knowledge productivity. These two constructs, within each kind of knowledge, added structure to the vague R & D based LTI model. The research questions and hypotheses testing were addressed using correlation analysis. The alternative hypotheses that there were positive relationships between knowledge factors and their corresponding types of innovation were accepted. In-depth study of each process is recommended in both research and application. Experimental tests are needed, in order to ultimately present the LTI model to enhance the scientific knowledge absorptive capacity of the learners to facilitate their innovation performance.

Cloud Computing Value Chains: Understanding Businesses and Value Creation in the Cloud

NASA Astrophysics Data System (ADS)

Mohammed, Ashraf Bany; Altmann, Jörn; Hwang, Junseok

Based on the promising developments in Cloud Computing technologies in recent years, commercial computing resource services (e.g. Amazon EC2) or software-as-a-service offerings (e.g. Salesforce. com) came into existence. However, the relatively weak business exploitation, participation, and adoption of other Cloud Computing services remain the main challenges. The vague value structures seem to be hindering business adoption and the creation of sustainable business models around its technology. Using an extensive analyze of existing Cloud business models, Cloud services, stakeholder relations, market configurations and value structures, this Chapter develops a reference model for value chains in the Cloud. Although this model is theoretically based on porter's value chain theory, the proposed Cloud value chain model is upgraded to fit the diversity of business service scenarios in the Cloud computing markets. Using this model, different service scenarios are explained. Our findings suggest new services, business opportunities, and policy practices for realizing more adoption and value creation paths in the Cloud.

Particle Creation at a Point Source by Means of Interior-Boundary Conditions

NASA Astrophysics Data System (ADS)

Lampart, Jonas; Schmidt, Julian; Teufel, Stefan; Tumulka, Roderich

2018-06-01

We consider a way of defining quantum Hamiltonians involving particle creation and annihilation based on an interior-boundary condition (IBC) on the wave function, where the wave function is the particle-position representation of a vector in Fock space, and the IBC relates (essentially) the values of the wave function at any two configurations that differ only by the creation of a particle. Here we prove, for a model of particle creation at one or more point sources using the Laplace operator as the free Hamiltonian, that a Hamiltonian can indeed be rigorously defined in this way without the need for any ultraviolet regularization, and that it is self-adjoint. We prove further that introducing an ultraviolet cut-off (thus smearing out particles over a positive radius) and applying a certain known renormalization procedure (taking the limit of removing the cut-off while subtracting a constant that tends to infinity) yields, up to addition of a finite constant, the Hamiltonian defined by the IBC.

Speaking Up For Science

NASA Astrophysics Data System (ADS)

Spilhaus, Fred

2005-06-01

The Smithsonian Institution's National Museum of Natural History in Washington D.C. is planning to show a film, "A Privileged Planet" that promotes creationism in the form of "intelligent design." The film is based on the book by Guillermo Gonzalez and Jay Wesley Richards, both affiliated with the Discovery Institute, which advocates teaching "intelligent design" as science in U.S. public schools. By associating with the Discovery Institute, the Smithsonian Institution will associate science with creationism and damage their credibility. The film is slated for airing on 23 June, unless the Smithsonian comes to its senses.Why is this important? Because the film promotes a long term strategy of the Discovery Institute (//www.discovery.org/csc/) to replace "materialistic science" with "intelligent design." The film fosters the idea that science should include the supernatural. This is unacceptable. AGU's position is clear, creationism is not science and AGU opposes all efforts to promote creationism as science, (The full text of the AGU position statement can be found at: //www.agu.org/sci_soc/policy/positions/evolution.shtml).

[Ethics guidelines for the creation and use of registries for biomedical research purposes].

PubMed

Abajo Iglesias, Francisco J de; Feito Grande, Lydia; Júdez Gutiérrez, Javier; Martín Arribas, M Concepción; Terracini, Benedetto; Pàmpols Ros, Teresa; Campos Castelló, Jaime; Martín Uranga, Amelia; Abascal Alonso, Moisés; Herrera Carranza, Joaquín; Sánchez Martínez, María José

2008-01-01

The clinical information stored in registries and records of different types is a fundamental tool for biomedical research. Up until just a few years ago, hardly any limitations existed on the creation and use of epidemiological registries or the use of information from pre-existing records for research purposes. This situation has changed substantially due mainly to the growing importance current laws place upon the safeguarding of the privacy and confidentiality of personal data. Although the legal framework is already quite explicit, a certain degree of leeway exists for ethical debate and prudence advice for the purpose of conducting valid, useful research with this information which will also respect the rights of the subjects and the laws in force. These guidelines deal with those aspects which have been considered relevant from an ethical standpoint in the handling of records and registries for research-related purposes, including not only the use but also the creation proper of the registries. A total of twenty-four recommendations are provided, grouped into ten sections: warranting of the creation of registry, organization and definition of responsibilities, scientific validity of the research project, ethical requirements of the collections of anonymous and anonymized data, ethical requirements of the registries including personal data, uses of medical records for research purposes, use of historical records of deceased individuals, contact with the research subjects, notification of results and review by a Research Ethics Committee.

Looking and listening for learning in arts- and humanities-based creations.

PubMed

Varpio, Lara; Grassau, Pamela; Hall, Pippa

2017-02-01

The arts and humanities are gradually gaining a foothold in health professions education as a means of supporting the development of future clinicians who are compassionate, critical and reflexive thinkers, while also strengthening clinical skills and practices that emphasise patient-centredness, collaboration and interprofessional practices. Assignments that tap into trainee creativity are increasingly used both to prepare learners for the demands of clinical work and to understand the personal and professional challenges learners face in these contexts. Health professions educators need methods for interpreting these creations in order to understand each learner's expressions. This paper describes two theoretical frameworks that can be used to understand trainees' unique learning experiences as they are expressed in arts- and humanities-based creations. The authors introduce the philosophical underpinnings and interpretation procedures of two theoretical frameworks that enable educators to 'hear' and 'see' the multilayered expressions embedded within arts- and humanities-based student creations: Gilligan's Listening Guide and Kress and van Leeuwen's approach to visual rhetoric. To illustrate how these frameworks can be used, the authors apply them to two creative summaries that learners made as part of a humanities-informed, interprofessional education intervention that took place in a non-acute-care teaching hospital. The interpretations of two creative summaries, a poem and a pair of paintings, highlight how applying these theoretical frameworks can offer important insights into learners' experiences. This cross-cutting edge paper describes how the Listening Guide and visual rhetoric can help health professions educators listen to and read the arts- and humanities-based creative expressions made by learners. Insights gained from these interpretations can advance the understanding of students' personal experiences in different learning environments and can inform curriculum development. © 2016 John Wiley & Sons Ltd and The Association for the Study of Medical Education.

Evolution of Incubation Models: Evidence from the Italian Incubation Industry

ERIC Educational Resources Information Center

Grandi, Alessandro; Grimaldi, Rosa

2004-01-01

This paper addresses the role of incubators in supporting new venture creation. A mapping of four different types of incubator is proposed: corporate private incubators (CPIs), independent private incubators (IPIs), business innovation centres (BICs) and university business incubators (UBIs). This mapping is exemplified through case studies of one…

The Relationship between Students' Performance on Conventional Standardized Mathematics Assessments and Complex Mathematical Modeling Problems

ERIC Educational Resources Information Center

Kartal, Ozgul; Dunya, Beyza Aksu; Diefes-Dux, Heidi A.; Zawojewski, Judith S.

2016-01-01

Critical to many science, technology, engineering, and mathematics (STEM) career paths is mathematical modeling--specifically, the creation and adaptation of mathematical models to solve problems in complex settings. Conventional standardized measures of mathematics achievement are not structured to directly assess this type of mathematical…

Psychic Powers, Astrology & Creationism in the Classroom?

ERIC Educational Resources Information Center

Eve, Raymond A.; Dunn, Dana

1990-01-01

Examined is the extent to which teachers actually hold pseudoscientific beliefs. Described are the study design, sources of pseudoscientific belief, and correlates with various types of pseudoscientific beliefs. Results indicate that many high school biology and life science teachers endorse these beliefs. Implications of this study are discussed.…

An Analytical Index to the Internet: Dreams of Utopia.

ERIC Educational Resources Information Center

Casey, Carol

1999-01-01

Explores the need for analytical indexes to access Internet resources. Considers bibliographic control, Web site design, keyword search engines, hierarchical subject indexes, and special indexes and compilations of links, and concludes that the creation of small, focused indexes may be the best solution for accessing specific types of digital…

Trees of Our National Forests.

ERIC Educational Resources Information Center

Forest Service (USDA), Washington, DC.

Presented is a description of the creation of the National Forests system, how trees grow, managing the National Forests, types of management systems, and managing for multiple use, including wildlife, water, recreation and other uses. Included are: (1) photographs; (2) line drawings of typical leaves, cones, flowers, and seeds; and (3)…

22 CFR 521.21 - Discovery.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 22 Foreign Relations 2 2013-04-01 2009-04-01 true Discovery. 521.21 Section 521.21 Foreign... Discovery. (a) The following types of discovery are authorized: (1) Requests for production of documents for... interpreted to require the creation of a document. (c) Unless mutually agreed to by the parties, discovery is...

38 CFR 42.21 - Discovery.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 38 Pensions, Bonuses, and Veterans' Relief 2 2012-07-01 2012-07-01 false Discovery. 42.21 Section... IMPLEMENTING THE PROGRAM FRAUD CIVIL REMEDIES ACT § 42.21 Discovery. (a) The following types of discovery are... creation of a document. (c) Unless mutually agreed to by the parties, discovery is available only as...

22 CFR 521.21 - Discovery.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 22 Foreign Relations 2 2014-04-01 2014-04-01 false Discovery. 521.21 Section 521.21 Foreign... Discovery. (a) The following types of discovery are authorized: (1) Requests for production of documents for... interpreted to require the creation of a document. (c) Unless mutually agreed to by the parties, discovery is...

22 CFR 521.21 - Discovery.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 22 Foreign Relations 2 2012-04-01 2009-04-01 true Discovery. 521.21 Section 521.21 Foreign... Discovery. (a) The following types of discovery are authorized: (1) Requests for production of documents for... interpreted to require the creation of a document. (c) Unless mutually agreed to by the parties, discovery is...

38 CFR 42.21 - Discovery.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 38 Pensions, Bonuses, and Veterans' Relief 2 2011-07-01 2011-07-01 false Discovery. 42.21 Section... IMPLEMENTING THE PROGRAM FRAUD CIVIL REMEDIES ACT § 42.21 Discovery. (a) The following types of discovery are... creation of a document. (c) Unless mutually agreed to by the parties, discovery is available only as...

22 CFR 521.21 - Discovery.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 22 Foreign Relations 2 2011-04-01 2009-04-01 true Discovery. 521.21 Section 521.21 Foreign... Discovery. (a) The following types of discovery are authorized: (1) Requests for production of documents for... interpreted to require the creation of a document. (c) Unless mutually agreed to by the parties, discovery is...

38 CFR 42.21 - Discovery.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 38 Pensions, Bonuses, and Veterans' Relief 2 2014-07-01 2014-07-01 false Discovery. 42.21 Section... IMPLEMENTING THE PROGRAM FRAUD CIVIL REMEDIES ACT § 42.21 Discovery. (a) The following types of discovery are... creation of a document. (c) Unless mutually agreed to by the parties, discovery is available only as...

38 CFR 42.21 - Discovery.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 38 Pensions, Bonuses, and Veterans' Relief 2 2013-07-01 2013-07-01 false Discovery. 42.21 Section... IMPLEMENTING THE PROGRAM FRAUD CIVIL REMEDIES ACT § 42.21 Discovery. (a) The following types of discovery are... creation of a document. (c) Unless mutually agreed to by the parties, discovery is available only as...

A Virtual World for Collaboration: The AETZone

ERIC Educational Resources Information Center

Cheney, Amelia W.; Sanders, Robert L.; Matzen, Nita J.; Bronack, Stephen C.; Riedl, Richard E.; Tashner, John H.

2009-01-01

Participation in learning communities, and the construction of knowledge in communities of practice, are important considerations in the use of 3D immersive worlds. This article describes the creation of this type of learning environment in AETZone, an immersive virtual environment in use within graduate programs at Appalachian State University…

22 CFR 521.21 - Discovery.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Discovery. 521.21 Section 521.21 Foreign... Discovery. (a) The following types of discovery are authorized: (1) Requests for production of documents for... interpreted to require the creation of a document. (c) Unless mutually agreed to by the parties, discovery is...

38 CFR 42.21 - Discovery.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Discovery. 42.21 Section... IMPLEMENTING THE PROGRAM FRAUD CIVIL REMEDIES ACT § 42.21 Discovery. (a) The following types of discovery are... creation of a document. (c) Unless mutually agreed to by the parties, discovery is available only as...

Simply Performance Assessment

ERIC Educational Resources Information Center

McLaughlin, Cheryl A.; McLaughlin, Felecia C.; Pringle, Rose M.

2013-01-01

This article presents the experiences of Miss Felecia McLaughlin, a fourth-grade teacher from the island of Jamaica who used the model proposed by Bass et al. (2009) to assess conceptual understanding of four of the six types of simple machines while encouraging collaboration through the creation of learning teams. Students had an opportunity to…

[Proposal for a new funding system for mental health departments. Results from an evaluative multicentre Italian study (I-psycost)].

PubMed

Grigoletti, Laura; Amaddeo, Francesco; Grassi, Aldrigo; Boldrini, Massimo; Chiappelli, Marco; Percudani, Mauro; Catapano, Francesco; Fiorillo, Andrea; Bartoli, Luca; Bacigalupi, Maurizio; Albanese, Paolo; Simonetti, Simona; Perali, Federico; De Agostini, Paola; Tansella, Michele

2006-01-01

To obtain a new, well-balanced mental health funding system, through the creation of (i) a list of psychiatric interventions provided by Italian Community-based Psychiatric Services (CPS), and associated costs; (ii) a new prospective funding system for patients with a high use of resources, based on packages of care. Five Italian Community-based Psychiatric Services collected data from 1250 patients during October 2002. Socio-demographical and clinical characteristics and GAF scores were collected at baseline. All psychiatric contacts during the following six months were registered and categorised into 24 service contact types. Using elasticity equation and contact characteristics, we estimate the costs of care. Cluster analysis techniques identified packages of care. Logistic regression defined predictive variables of high use patients. Multinomial Logistic Model assigned each patient to a package of care. The sample's socio-demographic characteristics are similar, but variations exist between the different CPS. Patients were then divided into two groups, and the group with the highest use of resources was divided into three smaller groups, based on number and type of services provided. Our findings show how is possible to develop a cost predictive model to assign patients with a high use of resources to a group that can provide the right level of care. For these patients it might be possible to apply a prospective per-capita funding system based on packages of care.

A Multi-touch Tool for Co-creation

NASA Astrophysics Data System (ADS)

Ludden, Geke D. S.; Broens, Tom

Multi-touch technology provides an attractive way for knowledge workers to collaborate. Co-creation is an important collaboration process in which collecting resources, creating results and distributing these results is essential. We propose a wall-based multi-touch system (called CoCreate) in which these steps are made easy due to the notion of connected private spaces and a shared co-create space. We present our ongoing work, expert evaluation of interaction scenarios and future plans.

NSWC-NADC interactive communication links for AN/UYS-1 loadtape creation and retrieval

NASA Astrophysics Data System (ADS)

Greathouse, D. M.

1984-09-01

This report contains an alternative method of communication (interactive vs. remote batch) with the Naval Air Development Center for the creation and retrieval of AN/UYS-1 Advanced Signal Processor (ASP) operational software loadtapes. Operational software for the Digital Acoustic Sensor Simulator (DASS) program is developed and maintained at the Naval Air Development Center (NADC). The Facility for Automated Software Production (FASP), an NADC-resident software generation facility, provides the support tools necessary for data base creation, software development and maintenance, and loadtape generation. Once a loadtape file is generated at NADC, it must be retrieved via telephone transmission and placed in a format suitable for loading into the AN/UYS-1 Advanced Signal Processor (ASP).

Thermoinduced laser-assisted deposition of molybdenum from aqueous solutions

NASA Astrophysics Data System (ADS)

Kochemirovsky, Vladimir V.; Logunov, Lev S.; Zhigley, Elvira S.; Baranauskaite, Valeriia

2015-05-01

Local molybdenum deposit obtainment is promising for micro thermocouples creation on dielectric surfaces. This paper is dedicated to development of method of laser-induced molybdenum deposition from water-based solution of inorganic salt on Sitall st-50 and glass dielectric substrates, as well as research of solution composition, pH and substrate optical properties influence on result of laser-induced molybdenum deposition from solution. It was shown that depending on dielectric substrate type, as a result of laser-induced deposition metallic molybdenum or molybdenum dioxide deposit forms: molybdenum dioxide deposits in case of optically clear substrate and metallic molybdenum deposits in case of opaque glass-ceramics. While modelling interim case via using clouded glass, mixture of molybdenum and its oxide was successfully obtained.

Novel approaches to development, delivery and evaluation of a peer-led occupational safety training for Latino day laborers.

PubMed

De Souza, Rachael Ann; Hecker, Steven; de Castro, A B; Stern, Hilary; Hernandez, Araceli; Seixas, Noah

2012-01-01

Latino day laborers experience high rates of work-related injuries and are a hard-to-reach group for safety interventions. This study describes the creation and implementation of safety training based in empowerment theory and its evaluation to address three levels in empowerment's hierarchy of change. Pictographic pre- and post-tests were used to assess knowledge level changes. Individual and large-group interviews were conducted to address attitudes and behavior-level changes. Results indicate that day laborers learn and apply lessons from this type of safety training. Findings also offer insight into challenges that day laborers encounter when trying to work safely as well as ideas for future training interventions.

Out of the frying pan: Explosive droplet dynamics

NASA Astrophysics Data System (ADS)

Marston, Jeremy; Li, Chao; Truscott, Tadd; Mansoor, Mohammad

2017-11-01

Regardless of culinary skills, most people who have used a stove top have encountered the result of water interacting with hot oil. The phenomenon is particularly memorable if the result is impingement of hot fluid on one's skin. Whilst ubiquitous, a deeper probing of this phenomenon reveals a vastly rich dynamical process. We use high-speed imaging to investigate the idealized case of a single water droplet impacting onto a hot oil film. At a qualitative level, we have observed three regimes of fluid ejection - jets, cones and explosive vaporization. The latter of these results in the spectacular creation of aerosol with sizes down to the sub-micrometer range. We present our experimental findings based upon control parameters such as temperature, film thickness and oil type.

Predicate Argument Structure Frames for Modeling Information in Operative Notes

PubMed Central

Wang, Yan; Pakhomov, Serguei; Melton, Genevieve B.

2015-01-01

The rich information about surgical procedures contained in operative notes is a valuable data source for improving the clinical evidence base and clinical research. In this study, we propose a set of Predicate Argument Structure (PAS) frames for surgical action verbs to assist in the creation of an information extraction (IE) system to automatically extract details about the techniques, equipment, and operative steps from operative notes. We created PropBank style PAS frames for the 30 top surgical action verbs based on examination of randomly selected sample sentences from 3,000 Laparoscopic Cholecystectomy notes. To assess completeness of the PAS frames to represent usage of same action verbs, we evaluated the PAS frames created on sample sentences from operative notes of 6 other gastrointestinal surgical procedures. Our results showed that the PAS frames created with one type of surgery can successfully denote the usage of the same verbs in operative notes of broader surgical categories. PMID:23920664

"It's In My Veins": Exploring the Role of an Afrocentric, Popular Education-Based Training Program in the Empowerment of African American and African Community Health Workers in Oregon.

PubMed

Bridgeman-Bunyoli, Arika; Mitchell, S Renee; Bin Abdullah, AbdulʼHafeedh M; Schwoeffermann, Ty; Phoenix, Toliver; Goughnour, Cat; Hines-Norwood, Richard; Wiggins, Noelle

2015-01-01

The role racism and other social determinants of health play in the creation of health inequities in African American communities in the United States is increasingly understood. In this article, we explore the effectiveness of an Afrocentric, popular education-based community health worker (CHW) training program in creating positive change among CHW participants and their communities in Portland, Oregon. Findings suggest that CHW participants experienced 4 types of awakening, in addition to changes in their interaction with their family members and increased community involvement. The CHWs identified group bond, Afrocentrism, public health knowledge, popular education, facilitators, and time management as important elements of an effective training program for this community. Psychological empowerment, self-reported health status, and health behavior among participants generally increased over time, but changes were not statistically significant.

Remote creation of hybrid entanglement between particle-like and wave-like optical qubits

NASA Astrophysics Data System (ADS)

Morin, Olivier; Huang, Kun; Liu, Jianli; Le Jeannic, Hanna; Fabre, Claude; Laurat, Julien

2014-07-01

The wave-particle duality of light has led to two different encodings for optical quantum information processing. Several approaches have emerged based either on particle-like discrete-variable states (that is, finite-dimensional quantum systems) or on wave-like continuous-variable states (that is, infinite-dimensional systems). Here, we demonstrate the generation of entanglement between optical qubits of these different types, located at distant places and connected by a lossy channel. Such hybrid entanglement, which is a key resource for a variety of recently proposed schemes, including quantum cryptography and computing, enables information to be converted from one Hilbert space to the other via teleportation and therefore the connection of remote quantum processors based upon different encodings. Beyond its fundamental significance for the exploration of entanglement and its possible instantiations, our optical circuit holds promise for implementations of heterogeneous network, where discrete- and continuous-variable operations and techniques can be efficiently combined.

Database systems for knowledge-based discovery.

PubMed

Jagarlapudi, Sarma A R P; Kishan, K V Radha

2009-01-01

Several database systems have been developed to provide valuable information from the bench chemist to biologist, medical practitioner to pharmaceutical scientist in a structured format. The advent of information technology and computational power enhanced the ability to access large volumes of data in the form of a database where one could do compilation, searching, archiving, analysis, and finally knowledge derivation. Although, data are of variable types the tools used for database creation, searching and retrieval are similar. GVK BIO has been developing databases from publicly available scientific literature in specific areas like medicinal chemistry, clinical research, and mechanism-based toxicity so that the structured databases containing vast data could be used in several areas of research. These databases were classified as reference centric or compound centric depending on the way the database systems were designed. Integration of these databases with knowledge derivation tools would enhance the value of these systems toward better drug design and discovery.

A block chain based architecture for asset management in coalition operations

NASA Astrophysics Data System (ADS)

Verma, Dinesh; Desai, Nirmit; Preece, Alun; Taylor, Ian

2017-05-01

To support dynamic communities of interests in coalition operations, new architectures for efficient sharing of ISR assets are needed. The use of blockchain technology in wired business environments, such as digital currency systems, offers an interesting solution by creating a way to maintain a distributed shared ledger without requiring a single trusted authority. In this paper, we discuss how a blockchain-based system can be modified to provide a solution for dynamic asset sharing amongst coalition members, enabling the creation of a logically centralized asset management system by a seamless policy-compliant federation of different coalition systems. We discuss the use of blockchain for three different types of assets in a coalition context, showing how blockchain can offer a suitable solution for sharing assets in those environments. We also discuss the limitations in the current implementations of blockchain which need to be overcome for the technology to become more effective in a decentralized tactical edge environment.

[Exposed workers to lung cancer risk. An estimation using the ISPESL database of enterprises].

PubMed

Scarselli, Alberto; Marinaccio, Alessandro; Nesti, Massimo

2007-01-01

lung cancer is the first cause of death in the industrialized country among males and is increasing among females. In 2001 a uniform and standardised list of occupations or jobs known or suspected to be associated with lung cancer has been prepared. The aim of this study is to set up a database of Italian enterprises corresponding to activities related to this list and to assess the number of potentially exposed workers. a detailed and unique list of codes, referred to Ateco91 ISTAT classification with exclusion of the State Railways and the public administration sectors, has been developed. The list is divided into two categories: respectively for occupations or jobs definitely entailing carcinogenic risk and for those which probably/possibly entail a risk. Firms have been selected from the ISPESL database of enterprises and the number of workers has been estimated on the basis of this list. Italy. assessment of the number of workers potentially exposed to lung cancer risk and creation of a register of involved firms. the number of potentially exposed workers in the industrial and services sector related to lung cancer risk is 650,886 blue collars and the number of firms censused in Italy is 117,006 units. Corresponding figures in the agriculture sector are 163,340 and 84,839. This type of evaluation, being based on administrative sources rather then on direct measures of exposure, certainly includes an overestimation of exposed workers. the lists based on a standard classification which have been created allow for the creation of databases which can be used to control occupational exposure to carcinogens and to increase comparability between epidemiologic studies based on job-exposure matrix.

Detecting Hardware-assisted Hypervisor Rootkits within Nested Virtualized Environments

DTIC Science & Technology

2012-06-14

least the minimum required for the guest OS and click “Next”. For 64-bit Windows 7 the minimum required is 2048 MB (Figure 66). Figure 66. Memory...prompted for Memory, allocate at least the minimum required for the guest OS, for 64-bit Windows 7 the minimum required is 2048 MB (Figure 79...130 21. Within the virtual disk creation wizard, select VDI for the file type (Figure 81). Figure 81. Select File Type 22. Select Dynamically

Dense gamma-ray and pair creation using ultra-intense lasers

NASA Astrophysics Data System (ADS)

Liang, Edison; Lo, Willie; Hasson, Hannah; Dyer, Gilliss; Clarke, Taylor; Fasanelli, Fabio; Yao, Kelly; Marchenka, Ilija; Henderson, Alexander; Dashko, Andriy; Zhang, Yuling; Ditmire, Todd

2016-10-01

We report recent results of gamma-ray and e +e- pair creation experiments using the Texas Petawatt laser (TPW) in Austin and the Trident laser at LANL irradiating solid high-Z targets. In addition to achieving record high densities of emerging gamma-rays and pairs at TPW, we measured in detail the spectra of hot electrons, positrons, and gamma-rays, and studied their spectral variation with laser and target parameters. A new type of gamma-ray spectrometer, called the scintillator attenuation spectrometer (SAS), was successfully demonstrated in Trident experiments in 2015. We will discuss the design and results of the SAS. Preliminary results of new experiments at TPW carried out in the summer of 2016 will also be presented.

Digital subtraction angiography during transjugular intrahepatic portosystemic shunt creation or revision: data on radiation exposure and image quality obtained using a standard and a low-dose acquisition protocol in a flat-panel detector-based system.

PubMed

Miraglia, Roberto; Maruzzelli, Luigi; Cortis, Kelvin; Tafaro, Corrado; Gerasia, Roberta; Parisi, Carmelo; Luca, Angelo

2015-08-01

To determine whether the use of a low-dose acquisition protocol (LDP) in digital subtraction angiography during transjugular intrahepatic portosystemic shunt (TIPS) creation/revision results in significant reduction of patient radiation exposure and adequate image quality, as compared to a default reference standard-dose acquisition protocol (SDP). Two angiographic runs were performed during TIPS creation/revision: the first following catheterization of the portal venous system and the second after stent deployment/angioplasty. Constant field of view, object to image-detector distance, and source to image-receptor distance were maintained in each patient during the two angiographic runs. 17 consecutive adult patients who underwent TIPS creation (n = 11) or TIPS revision (n = 6) from December 2013 to March 2014 were considered eligible for this single centre prospective study. In each patient, the LDP and the SDP were used in a random order for the two runs, with each patient serving as his/her own control. The dose-area product (DAP) was calculated for each image and compared. Image quality was graded by two interventional radiologists other than the operator. In all runs acquired with the LDP, image quality was considered adequate for a successful procedural outcome. The DAP per image of the LDP was numerically inferior as compared to the DAP per image of the SDP in all patients. The mean reduction in DAP per image was 75.24% ± 5.7% (p < 0. 001). Radiation exposure during TIPS creation/revision was significantly reduced by selecting a LDP in our flat-panel detector-based system, while maintaining adequate image quality.

Code IN Exhibits - Supercomputing 2000

NASA Technical Reports Server (NTRS)

Yarrow, Maurice; McCann, Karen M.; Biswas, Rupak; VanderWijngaart, Rob F.; Kwak, Dochan (Technical Monitor)

2000-01-01

The creation of parameter study suites has recently become a more challenging problem as the parameter studies have become multi-tiered and the computational environment has become a supercomputer grid. The parameter spaces are vast, the individual problem sizes are getting larger, and researchers are seeking to combine several successive stages of parameterization and computation. Simultaneously, grid-based computing offers immense resource opportunities but at the expense of great difficulty of use. We present ILab, an advanced graphical user interface approach to this problem. Our novel strategy stresses intuitive visual design tools for parameter study creation and complex process specification, and also offers programming-free access to grid-based supercomputer resources and process automation.

Principles of visual key construction-with a visual identification key to the Fagaceae of the southeastern United States.

PubMed

Kirchoff, Bruce K; Leggett, Roxanne; Her, Va; Moua, Chue; Morrison, Jessica; Poole, Chamika

2011-01-01

Advances in digital imaging have made possible the creation of completely visual keys. By a visual key we mean a key based primarily on images, and that contains a minimal amount of text. Characters in visual keys are visually, not verbally defined. In this paper we create the first primarily visual key to a group of taxa, in this case the Fagaceae of the southeastern USA. We also modify our recently published set of best practices for image use in illustrated keys to make them applicable to visual keys. Photographs of the Fagaceae were obtained from internet and herbarium databases or were taken specifically for this project. The images were printed and then sorted into hierarchical groups. These hierarchical groups of images were used to create the 'couplets' in the key. A reciprocal process of key creation and testing was used to produce the final keys. Four keys were created, one for each of the parts-leaves, buds, fruits and bark. Species description pages consisting of multiple images were also created for each of the species in the key. Creation and testing of the key resulted in a modified list of best practices for image use visual keys. The inclusion of images into paper and electronic keys has greatly increased their ease of use. However, virtually all of these keys are still based upon verbally defined, atomistic characters. The creation of primarily visual keys allows us to overcome the well-known limitations of linguistic-based characters and create keys that are much easier to use, especially for botanical novices.

Graphical explanation in an expert system for Space Station Freedom rack integration

NASA Technical Reports Server (NTRS)

Craig, F. G.; Cutts, D. E.; Fennel, T. R.; Purves, B.

1990-01-01

The rationale and methodology used to incorporate graphics into explanations provided by an expert system for Space Station Freedom rack integration is examined. The rack integration task is typical of a class of constraint satisfaction problems for large programs where expertise from several areas is required. Graphically oriented approaches are used to explain the conclusions made by the system, the knowledge base content, and even at more abstract levels the control strategies employed by the system. The implemented architecture combines hypermedia and inference engine capabilities. The advantages of this architecture include: closer integration of user interface, explanation system, and knowledge base; the ability to embed links to deeper knowledge underlying the compiled knowledge used in the knowledge base; and allowing for more direct control of explanation depth and duration by the user. The graphical techniques employed range from simple statis presentation of schematics to dynamic creation of a series of pictures presented motion picture style. User models control the type, amount, and order of information presented.

Geomorphology as science: the role of theory

NASA Astrophysics Data System (ADS)

Rhoads, Bruce L.; Thorn, Colin E.

1993-04-01

Because geomorphology is a science, it is permeated by theory. Overt recognition of this actuality is frequently resisted by geomorphologists. Earth history does not represent an alternative to earth science, it is an essential component of earth science. In its broadest sense science seeks to discover new knowledge through a two-stage activity involving the creation and justification of ideas (theory). Deduction is generally regarded as the only logically-consistent method of justifying ideas. The creation of ideas is a much more controversial topic. Some methodologists deem it beyond logic; certainly deductive arguments, which are nothing more than formal, logical expressions of theory, play no role in the conception of new ideas. Many earth scientists generate possible explanations of observed phenomena based on abductive reasoning. Others advocate reliance on purported forms of "pure" induction, such as serendipity and intuition, in which observations assume primacy over theory. Besides lacking consistency and educability, the latter posture is flawed because it mistakenly implies that becoming well-versed in theory is irrelevant to or impedes scientific discovery. Irrational or subjective factors play a role in the creation of ideas, but it is erroneous to claim that these factors are divorced from theory. Science is first and foremost a cognitive activity; thus, the primacy of observations in science is a myth. All observations are theory-laden in the sense that the act of observation inherently involves interpretation and classification, both of which can only occur within the context of theoretical preconceptions. Even discoveries based on unexpected observations require the fortunate investigator to recognize the theoretical importance of what is seen or measured. The most useful view of geomorphology as a science is one in which theory is seen as central, but fragile, and in which theory and observation are viewed symbiotically with theory providing the generative force and observation providing a vital policing role. Much of the current debate in geomorphology centers around differences in characteristics of theory, type of scientific arguments, and metaphysical perspectives among investigators working at different temporal scales. Full recognition and understanding of these differences are essential for developing a unified approach to the science of geomorphology.

Biowep: a workflow enactment portal for bioinformatics applications.

PubMed

Romano, Paolo; Bartocci, Ezio; Bertolini, Guglielmo; De Paoli, Flavio; Marra, Domenico; Mauri, Giancarlo; Merelli, Emanuela; Milanesi, Luciano

2007-03-08

The huge amount of biological information, its distribution over the Internet and the heterogeneity of available software tools makes the adoption of new data integration and analysis network tools a necessity in bioinformatics. ICT standards and tools, like Web Services and Workflow Management Systems (WMS), can support the creation and deployment of such systems. Many Web Services are already available and some WMS have been proposed. They assume that researchers know which bioinformatics resources can be reached through a programmatic interface and that they are skilled in programming and building workflows. Therefore, they are not viable to the majority of unskilled researchers. A portal enabling these to take profit from new technologies is still missing. We designed biowep, a web based client application that allows for the selection and execution of a set of predefined workflows. The system is available on-line. Biowep architecture includes a Workflow Manager, a User Interface and a Workflow Executor. The task of the Workflow Manager is the creation and annotation of workflows. These can be created by using either the Taverna Workbench or BioWMS. Enactment of workflows is carried out by FreeFluo for Taverna workflows and by BioAgent/Hermes, a mobile agent-based middleware, for BioWMS ones. Main workflows' processing steps are annotated on the basis of their input and output, elaboration type and application domain by using a classification of bioinformatics data and tasks. The interface supports users authentication and profiling. Workflows can be selected on the basis of users' profiles and can be searched through their annotations. Results can be saved. We developed a web system that support the selection and execution of predefined workflows, thus simplifying access for all researchers. The implementation of Web Services allowing specialized software to interact with an exhaustive set of biomedical databases and analysis software and the creation of effective workflows can significantly improve automation of in-silico analysis. Biowep is available for interested researchers as a reference portal. They are invited to submit their workflows to the workflow repository. Biowep is further being developed in the sphere of the Laboratory of Interdisciplinary Technologies in Bioinformatics - LITBIO.

Biowep: a workflow enactment portal for bioinformatics applications

PubMed Central

Romano, Paolo; Bartocci, Ezio; Bertolini, Guglielmo; De Paoli, Flavio; Marra, Domenico; Mauri, Giancarlo; Merelli, Emanuela; Milanesi, Luciano

2007-01-01

Background The huge amount of biological information, its distribution over the Internet and the heterogeneity of available software tools makes the adoption of new data integration and analysis network tools a necessity in bioinformatics. ICT standards and tools, like Web Services and Workflow Management Systems (WMS), can support the creation and deployment of such systems. Many Web Services are already available and some WMS have been proposed. They assume that researchers know which bioinformatics resources can be reached through a programmatic interface and that they are skilled in programming and building workflows. Therefore, they are not viable to the majority of unskilled researchers. A portal enabling these to take profit from new technologies is still missing. Results We designed biowep, a web based client application that allows for the selection and execution of a set of predefined workflows. The system is available on-line. Biowep architecture includes a Workflow Manager, a User Interface and a Workflow Executor. The task of the Workflow Manager is the creation and annotation of workflows. These can be created by using either the Taverna Workbench or BioWMS. Enactment of workflows is carried out by FreeFluo for Taverna workflows and by BioAgent/Hermes, a mobile agent-based middleware, for BioWMS ones. Main workflows' processing steps are annotated on the basis of their input and output, elaboration type and application domain by using a classification of bioinformatics data and tasks. The interface supports users authentication and profiling. Workflows can be selected on the basis of users' profiles and can be searched through their annotations. Results can be saved. Conclusion We developed a web system that support the selection and execution of predefined workflows, thus simplifying access for all researchers. The implementation of Web Services allowing specialized software to interact with an exhaustive set of biomedical databases and analysis software and the creation of effective workflows can significantly improve automation of in-silico analysis. Biowep is available for interested researchers as a reference portal. They are invited to submit their workflows to the workflow repository. Biowep is further being developed in the sphere of the Laboratory of Interdisciplinary Technologies in Bioinformatics – LITBIO. PMID:17430563

Developing Vocabularies to Improve Understanding and Use of NOAA Observing Systems

NASA Astrophysics Data System (ADS)

Austin, M.

2014-12-01

The NOAA Observing System Integrated Analysis project (NOSIA II), is an attempt to capture and tell the story of how valuable observing systems are in producing products and services that are required to fulfill the NOAA's diverse mission. NOAA's goals and mission areas cover a broad range of environmental data; a complexity exists in terms and vocabulary as applied to the creation of observing system derived products. The NOSIA data collection focused first on decomposing NOAA's goals in the creation and acceptance of Mission Service Areas (MSAs) by NOAA senior leadership. Products and services that supported the MSAs were then identified through the process of interviewing product producers across NOAA organization. Product Data inputs including models, databases and observing system were also identified. The NOSIA model contains over 20,000 nodes each representing levels in a network connecting products, datasources, users and desired outcomes. An immediate need became apparent that the complexity and variety of the data collected required data management to mature the quality and the content of the NOSIA model. The NOSIA Analysis Database (ADB) was developed initially to improve consistency of terms and data types to allow for the linkage of observing systems, products and NOAA's Goals and mission. The ADB also allowed for the prototyping of reports and product generation in an easily accessible and comprehensive format for the first time. Web based visualization of relationships between products, datasources, users, producers were generated to make the information easily understood This includes developing ontologies/vocabularies that are used for the development of users type specific products for NOAA leadership, Observing System Portfolio mangers and the users of NOAA data.

Physicochemical and osteoplastic characteristics of 3D printed bone grafts based on synthetic calcium phosphates and natural polymers

NASA Astrophysics Data System (ADS)

Nezhurina, E. K.; Karalkin, P. A.; Komlev, V. S.; Sviridova, I. K.; Kirsanova, V. A.; Akhmedova, S. A.; Shanskiy, Ya D.; Fedotov, A. Yu; Barinov, S. M.; Sergeeva, N. S.

2018-04-01

A creation of personalized implants for regeneration of bone tissue seems to be a very promising biomedical technological approach. We have studied the physicochemical characteristics, cyto- and biocompatibility of three-dimensional constructs based on sodium alginate and gelatin in combination with 2 types of calcium phosphate (tricalcium phosphate or octacalcium phosphate) obtained by inkjet 3D printing. In our experiments, we have studied the physical and chemical properties of the constructs – their porosity, chemical composition, microarchitecture of the surface and mechanical elasticity. The cytocompatibility of 3D constructs and matrix-for-cell properties were investigated in vitro on a model of human osteosarcoma MG-63 cell line by means of MTT assay. The biocompatibility of 3D constructs was studied on the model of subcutaneous implantation in mice up to 12 weeks. All types of 3D constructs were cytocompatible in vitro, demonstrated good matrix-for-cells properties, and had supported cell proliferation for 2 weeks. In results of subcutaneous in vivo test all constructs demonstrated biocompatibility with slow bioresorption of organic and inorganic components. Osteogenesis proceeded more actively in rat tibia model defects (marginal excision), substituted by 3D printed 3-component implants based on alginate, gelatin and octacalcium phosphate.

Fault tolerance in computational grids: perspectives, challenges, and issues.

PubMed

Haider, Sajjad; Nazir, Babar

2016-01-01

Computational grids are established with the intention of providing shared access to hardware and software based resources with special reference to increased computational capabilities. Fault tolerance is one of the most important issues faced by the computational grids. The main contribution of this survey is the creation of an extended classification of problems that incur in the computational grid environments. The proposed classification will help researchers, developers, and maintainers of grids to understand the types of issues to be anticipated. Moreover, different types of problems, such as omission, interaction, and timing related have been identified that need to be handled on various layers of the computational grid. In this survey, an analysis and examination is also performed pertaining to the fault tolerance and fault detection mechanisms. Our conclusion is that a dependable and reliable grid can only be established when more emphasis is on fault identification. Moreover, our survey reveals that adaptive and intelligent fault identification, and tolerance techniques can improve the dependability of grid working environments.

Developing a Statewide Library Network.

ERIC Educational Resources Information Center

Trezza, Alphonse F.

1975-01-01

The first step in establishing a statewide library network in Minnesota is to seek passage of enabling legislation which would create a single network for all types of state libraries. Membership in the network should be voluntary, and control of budgets, staffs, and collections should remain at the local level. Creation of such statewide networks…

Internal Capabilities, External Network Position, and Knowledge Creation

ERIC Educational Resources Information Center

Liao, Yin-Chi

2010-01-01

Despite the general consensus on the importance of interfirm networks, there is an ongoing debate centering on which type of network structure is most beneficial to firm performance. While spanning structural holes--a network position with disconnected partners--is argued to be advantageous in terms of providing access to diverse knowledge,…

Cloud Computing and Validated Learning for Accelerating Innovation in IoT

ERIC Educational Resources Information Center

Suciu, George; Todoran, Gyorgy; Vulpe, Alexandru; Suciu, Victor; Bulca, Cristina; Cheveresan, Romulus

2015-01-01

Innovation in Internet of Things (IoT) requires more than just creation of technology and use of cloud computing or big data platforms. It requires accelerated commercialization or aptly called go-to-market processes. To successfully accelerate, companies need a new type of product development, the so-called validated learning process.…

SENSIT.FOR: A program for sensitometric reduction

NASA Astrophysics Data System (ADS)

Maury, A.; Marchal, J.

1984-09-01

A FORTRAN program for sensitometric evaluation of processes involved in hypering astronomical plates was written. It contains subroutines for full or quick description of the operation being done; choice of type of sensitogram; creation of 16 subfiles in the scan; density filtering; correction for area; specular PDS to diffuse ISO density calibration; and fog correction.

31 CFR 16.21 - Discovery.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 31 Money and Finance: Treasury 1 2012-07-01 2012-07-01 false Discovery. 16.21 Section 16.21 Money... FRAUD CIVIL REMEDIES ACT OF 1986 § 16.21 Discovery. (a) The following types of discovery are authorized... to require the creation of a document. (c) Unless mutually agreed to by the parties, discovery is...

31 CFR 16.21 - Discovery.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 31 Money and Finance: Treasury 1 2013-07-01 2013-07-01 false Discovery. 16.21 Section 16.21 Money... FRAUD CIVIL REMEDIES ACT OF 1986 § 16.21 Discovery. (a) The following types of discovery are authorized... to require the creation of a document. (c) Unless mutually agreed to by the parties, discovery is...

31 CFR 16.21 - Discovery.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 31 Money and Finance: Treasury 1 2014-07-01 2014-07-01 false Discovery. 16.21 Section 16.21 Money... FRAUD CIVIL REMEDIES ACT OF 1986 § 16.21 Discovery. (a) The following types of discovery are authorized... to require the creation of a document. (c) Unless mutually agreed to by the parties, discovery is...

31 CFR 16.21 - Discovery.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 31 Money and Finance: Treasury 1 2011-07-01 2011-07-01 false Discovery. 16.21 Section 16.21 Money... FRAUD CIVIL REMEDIES ACT OF 1986 § 16.21 Discovery. (a) The following types of discovery are authorized... to require the creation of a document. (c) Unless mutually agreed to by the parties, discovery is...

31 CFR 16.21 - Discovery.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 31 Money and Finance: Treasury 1 2010-07-01 2010-07-01 false Discovery. 16.21 Section 16.21 Money... FRAUD CIVIL REMEDIES ACT OF 1986 § 16.21 Discovery. (a) The following types of discovery are authorized... to require the creation of a document. (c) Unless mutually agreed to by the parties, discovery is...

The Cancer Cell Map Initiative: Defining the Hallmark Networks of Cancer

PubMed Central

Krogan, Nevan J.; Lippman, Scott; Agard, David A.; Ashworth, Alan; Ideker, Trey

2017-01-01

Progress in DNA sequencing has revealed the startling complexity of cancer genomes, which typically carry thousands of somatic mutations. However, it remains unclear which are the key driver mutations or dependencies in a given cancer and how these influence pathogenesis and response to therapy. Although tumors of similar types and clinical outcomes can have patterns of mutations that are strikingly different, it is becoming apparent that these mutations recurrently hijack the same hallmark molecular pathways and networks. For this reason, it is likely that successful interpretation of cancer genomes will require comprehensive knowledge of the molecular networks under selective pressure in oncogenesis. Here we announce the creation of a new effort, called The Cancer Cell Map Initiative (CCMI), aimed at systematically detailing these complex interactions among cancer genes and how they differ between diseased and healthy states. We discuss recent progress that enables creation of these Cancer Cell Maps across a range of tumor types and how they can be used to target networks disrupted in individual patients, significantly accelerating the development of precision medicine. PMID:26000852

The cancer cell map initiative: defining the hallmark networks of cancer.

PubMed

Krogan, Nevan J; Lippman, Scott; Agard, David A; Ashworth, Alan; Ideker, Trey

2015-05-21

Progress in DNA sequencing has revealed the startling complexity of cancer genomes, which typically carry thousands of somatic mutations. However, it remains unclear which are the key driver mutations or dependencies in a given cancer and how these influence pathogenesis and response to therapy. Although tumors of similar types and clinical outcomes can have patterns of mutations that are strikingly different, it is becoming apparent that these mutations recurrently hijack the same hallmark molecular pathways and networks. For this reason, it is likely that successful interpretation of cancer genomes will require comprehensive knowledge of the molecular networks under selective pressure in oncogenesis. Here we announce the creation of a new effort, The Cancer Cell Map Initiative (CCMI), aimed at systematically detailing these complex interactions among cancer genes and how they differ between diseased and healthy states. We discuss recent progress that enables creation of these cancer cell maps across a range of tumor types and how they can be used to target networks disrupted in individual patients, significantly accelerating the development of precision medicine. Copyright © 2015 Elsevier Inc. All rights reserved.

Cadastre (forest maps) and spatial land uses planning, strategic tool for sustainable development

NASA Astrophysics Data System (ADS)

Drosos, Vasileios C.

2014-08-01

The rise in the living standards of the Greeks created, especially since 1970, along with other needs and the need for second or holiday home since 1990 after finding the first house on the outskirts of large urban centers. Trying to find land for the creation of new resorts or new type of permanent residences (maisonettes with or without garden, depending on the financial position of each) had the painful consequence of wasteful and uncontrolled use of land, without a program, without the fundamental rules of land planning and the final creation was usually unsightly buildings. The costs were to pay as usually the forest rural lands. The national spatial planning of land use requires that we know the existing land uses in this country, and based on that we can design and decide their land uses on the future in a rational way. On final practical level, this planning leads to mark the boundaries of specific areas of land that are permitted and may change uses. For this reason, one of the most valuable "tools" of that final marking the boundaries is also the forest maps. The paper aims the investigation to determine the modern views on the issues of Cadastre and Land Management with an ulterior view to placing the bases for creating a building plan of an immediate completion of forest maps. Sustainable development as a term denoting a policy of continued economic and social development that does not involve the destruction of the environment and natural resources, but rather guarantees their rational viability.

Do Adults Show an Effect of Delayed First Language Acquisition When Calculating Scalar Implicatures?

PubMed

Davidson, Kathryn; Mayberry, Rachel I

Language acquisition involves learning not only grammatical rules and a lexicon, but also what someone is intending to convey with their utterance: the semantic/pragmatic component of language. In this paper we separate the contributions of linguistic development and cognitive maturity to the acquisition of the semantic/pragmatic component of language by comparing deaf adults who had either early or late first exposure to their first language (ASL). We focus on the particular type of meaning at the semantic/pragmatic interface called scalar implicature , for which preschool-age children typically differ from adults. Children's behavior has been attributed to either their not knowing appropriate linguistic alternatives to consider or to cognitive developmental differences between children and adults. Unlike children, deaf adults with late language exposure are cognitively mature, although they never fully acquire some complex linguistic structures, and thus serve as a test for the role of language in such interpretations. Our results indicate an overall high performance by late learners, especially when implicatures are not based on conventionalized items. However, compared to early language learners, late language learners compute fewer implicatures when conventionalized linguistic alternatives are involved (e.g. ). We conclude that (i) in general, Gricean pragmatic reasoning does not seem to be impacted by delayed first language acquisition and can account for multiple quantity implicatures, but (ii) the creation of a scale based on lexical items can lead to ease in alternative creation that may be advantageously learned early in life, and that this may be one of several factors contributing to differences between adults and children on scalar implicature tasks.

Recent processing methods for preparing starch-based bioproducts

USDA-ARS?s Scientific Manuscript database

There is currently an intense interest in starch-based materials because of the low cost of starch, the replacement of dwindling petroleum-based resources with annually-renewable feedstocks, the biodegradability of starch-based products, and the creation of new markets for farm commodities. Non-trad...

Dairy Analytics and Nutrient Analysis (DANA) Prototype System User Manual

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sam Alessi; Dennis Keiser

2012-10-01

This document is a user manual for the Dairy Analytics and Nutrient Analysis (DANA) model. DANA provides an analysis of dairy anaerobic digestion technology and allows users to calculate biogas production, co-product valuation, capital costs, expenses, revenue and financial metrics, for user customizable scenarios, dairy and digester types. The model provides results for three anaerobic digester types; Covered Lagoons, Modified Plug Flow, and Complete Mix, and three main energy production technologies; electricity generation, renewable natural gas generation, and compressed natural gas generation. Additional options include different dairy types, bedding types, backend treatment type as well as numerous production, and economicmore » parameters. DANA’s goal is to extend the National Market Value of Anaerobic Digester Products analysis (informa economics, 2012; Innovation Center, 2011) to include a greater and more flexible set of regional digester scenarios and to provide a modular framework for creation of a tool to support farmer and investor needs. Users can set up scenarios from combinations of existing parameters or add new parameters, run the model and view a variety of reports, charts and tables that are automatically produced and delivered over the web interface. DANA is based in the INL’s analysis architecture entitled Generalized Environment for Modeling Systems (GEMS) , which offers extensive collaboration, analysis, and integration opportunities and greatly speeds the ability construct highly scalable web delivered user-oriented decision tools. DANA’s approach uses server-based data processing and web-based user interfaces, rather a client-based spreadsheet approach. This offers a number of benefits over the client-based approach. Server processing and storage can scale up to handle a very large number of scenarios, so that analysis of county, even field level, across the whole U.S., can be performed. Server based databases allow dairy and digester parameters be held and managed in a single managed data repository, while allows users to customize standard values and perform individual analysis. Server-based calculations can be easily extended, versions and upgrades managed, and any changes are immediately available to all users. This user manual describes how to use and/or modify input database tables, run DANA, view and modify reports.« less

Dust dynamics in off-road vehicle trails: Measurements on 16 arid soil types, Nevada, USA.

PubMed

Goossens, Dirk; Buck, Brenda

2009-08-01

Soil analyses and measurements with the Portable In Situ Wind Erosion Laboratory (PI-SWERL) were conducted on 16 soil types in an area heavily affected by off-road vehicle (ORV) driving. Measurements were performed in ORV trails as well as on undisturbed terrain to investigate how ORV driving affects the vulnerability of a soil to emit PM10 (particles<10microm), during the driving as well as during episodes of wind erosion. Particular attention is paid to how the creation of a new trail affects those properties of the topsoil that determine its capability to emit PM10. Also, recommendations are given for adequate management of ORV-designed areas. The type of surface (sand, silt, gravel, drainage) is a key factor with respect to dust emission in an ORV trail. Trails in sand, defined in this study as the grain size fraction 63-2000microm, show higher deflation thresholds (the critical wind condition at which wind erosion starts) than the surrounding undisturbed soil. Trails in silt (2-63microm) and in drainages, on the other hand, have lower deflation thresholds than undisturbed soil. The increase in PM10 emission resulting from the creation of a new ORV trail is much higher for surfaces with silt than for surfaces with sand. Also, the creation of a new trail in silt decreases the supply limitation in the top layer: the capacity of the reservoir of emission-available PM10 increases. For sand the situation is reversed: the supply limitation increases, and the capacity of the PM10 reservoir decreases. Finally, ORV trails are characterized by a progressive coarsening of the top layer with time, but the speed of coarsening is much lower in trails in silt than in trails in sand or in drainages. The results of this study suggest that, to minimize emissions of PM10, new ORV fields should preferably be designed on sandy terrain rather than in silt areas or in drainages.

The history of the creation of Astronomy & Astrophysics

NASA Astrophysics Data System (ADS)

Pottasch, S. R.

2011-07-01

Dutch astronomer S.R. Pottasch, who was appointed as one of the two first Editors-in-Chief of A&A together with J.L. Steinberg, recalls the events that led to the creation of the first European astronomy journal. This account is based on the author's notes and documents and also on an article relating ESO's early history written by A. Blaauw and published in The ESO Messenger No. 60, pp. 23-34 (1990). C. Bertout added footnotes giving a few biographical details about the actors.

Recruiting the Cyber Leader: An Evaluation of the Human Resource Model Used for Recruiting the Army’s Cyber Operations Officer

DTIC Science & Technology

2017-09-01

For the first time since the creation of the Special Forces branch in 1987, the Army authorized the creation of a new branch, the Cyber branch. With...management model. The purpose of our research is to evaluate the effectiveness of that model to recruit Cyber Operations Officers and to examine the...performance (MOPs) and measures of effectiveness (MOEs) based on data collected from: Army institutions; a survey of the Cyber Branch population; and the

Automated rule-base creation via CLIPS-Induce

NASA Technical Reports Server (NTRS)

Murphy, Patrick M.

1994-01-01

Many CLIPS rule-bases contain one or more rule groups that perform classification. In this paper we describe CLIPS-Induce, an automated system for the creation of a CLIPS classification rule-base from a set of test cases. CLIPS-Induce consists of two components, a decision tree induction component and a CLIPS production extraction component. ID3, a popular decision tree induction algorithm, is used to induce a decision tree from the test cases. CLIPS production extraction is accomplished through a top-down traversal of the decision tree. Nodes of the tree are used to construct query rules, and branches of the tree are used to construct classification rules. The learned CLIPS productions may easily be incorporated into a large CLIPS system that perform tasks such as accessing a database or displaying information.

Development of an indexed integrated neuroradiology reports for teaching file creation

NASA Astrophysics Data System (ADS)

Tameem, Hussain Z.; Morioka, Craig; Bennett, David; El-Saden, Suzie; Sinha, Usha; Taira, Ricky; Bui, Alex; Kangarloo, Hooshang

2007-03-01

The decrease in reimbursement rates for radiology procedures has placed even more pressure on radiology departments to increase their clinical productivity. Clinical faculties have less time for teaching residents, but with the advent and prevalence of an electronic environment that includes PACS, RIS, and HIS, there is an opportunity to create electronic teaching files for fellows, residents, and medical students. Experienced clinicians, who select the most appropriate radiographic image, and clinical information relevant to that patient, create these teaching files. Important cases are selected based on the difficulty in determining the diagnosis or the manifestation of rare diseases. This manual process of teaching file creation is time consuming and may not be practical under the pressure of increased demands on the radiologist. It is the goal of this research to automate the process of teaching file creation by manually selecting key images and automatically extracting key sections from clinical reports and laboratories. The text report is then processed for indexing to two standard nomenclatures UMLS and RADLEX. Interesting teaching files can then be queried based on specific anatomy and findings found within the clinical reports.

The Latin-American region and the challenges to develop one homogeneous and harmonized hazard model: preliminary results for the Caribbean and Central America regions in the GEM context

NASA Astrophysics Data System (ADS)

Garcia, J.; Arcila, M.; Benito, B.; Eraso, J.; García, R.; Gomez Capera, A.; Pagani, M.; Pinho, R.; Rendon, H.; Torres, Y.

2013-05-01

Latin America is a seismically active region with complex tectonic settings that make the creation of hazard models challenging. Over the past two decades PSHA studies have been completed for this region in the context of global (Shedlock, 1999), regional (Dimaté et al., 1999) and national initiatives. Currently different research groups are developing new models for various nations. The Global Earthquake Model (GEM), an initiative aiming at the creation of a large global community working collaboratively on building hazard and risk models using open standards and tools, is promoting the collaboration between different national projects and groups so as to facilitate the creation of harmonized regional models. The creation of a harmonized hazard model can follow different approaches, varying from a simple patching of available models to a complete homogenisation of basic information and the subsequent creation of a completely new PSHA model. In this contribution we describe the process and results of a first attempt aiming at the creation of a community based model covering the Caribbean and Central America regions. It consists of five main steps: 1- Identification and collection of available PSHA input models; 2- Analysis of the consistency, transparency and reproducibility of each model; 3- Selection (if more then a model exists for the same region); 4- Representation of the models in a standardized format and incorporation of new knowledge from recent studies; 5- Proposal(s) of harmonization We consider some PHSA studies completed over the latest twenty years in the region comprising the Caribbean (CAR), Central America (CAM) and northern South America (SA), we illustrate a tentative harmonization of the seismic source geometries models and we discuss the steps needed toward a complete harmonisation of the models. Our will is to have a model based on best practices and high standards created though a combination of knowledge and competences coming from the scientific community, incorporating national and regional Institutions. This is an ambitious goal that can be pursued only through an intense and open cooperation between all the interested subjects.

An Advanced User Interface Approach for Complex Parameter Study Process Specification in the Information Power Grid

NASA Technical Reports Server (NTRS)

Yarrow, Maurice; McCann, Karen M.; Biswas, Rupak; VanderWijngaart, Rob; Yan, Jerry C. (Technical Monitor)

2000-01-01

The creation of parameter study suites has recently become a more challenging problem as the parameter studies have now become multi-tiered and the computational environment has become a supercomputer grid. The parameter spaces are vast, the individual problem sizes are getting larger, and researchers are now seeking to combine several successive stages of parameterization and computation. Simultaneously, grid-based computing offers great resource opportunity but at the expense of great difficulty of use. We present an approach to this problem which stresses intuitive visual design tools for parameter study creation and complex process specification, and also offers programming-free access to grid-based supercomputer resources and process automation.

Is employer-based health insurance a barrier to entrepreneurship?

PubMed

Fairlie, Robert W; Kapur, Kanika; Gates, Susan

2011-01-01

The focus on employer-provided health insurance in the United States may restrict business creation. We address the limited research on the topic of "entrepreneurship lock" by using recent panel data from matched Current Population Surveys. We use difference-in-difference models to estimate the interaction between having a spouse with employer-based health insurance and potential demand for health care. We find evidence of a larger negative effect of health insurance demand on business creation for those without spousal coverage than for those with spousal coverage. We also take a new approach in the literature to examine the question of whether employer-based health insurance discourages business creation by exploiting the discontinuity created at age 65 through the qualification for Medicare. Using a novel procedure of identifying age in months from matched monthly CPS data, we compare the probability of business ownership among male workers in the months just before turning age 65 and in the months just after turning age 65. We find that business ownership rates increase from just under age 65 to just over age 65, whereas we find no change in business ownership rates from just before to just after for other ages 55-75. We also do not find evidence from the previous literature and additional estimates that other confounding factors such as retirement, partial retirement, social security and pension eligibility are responsible for the increase in business ownership in the month individuals turn 65. Our estimates provide some evidence that "entrepreneurship lock" exists, which raises concerns that the bundling of health insurance and employment may create an inefficient level of business creation. Copyright © 2010 Elsevier B.V. All rights reserved.

A User-Centric Knowledge Creation Model in a Web of Object-Enabled Internet of Things Environment

PubMed Central

Kibria, Muhammad Golam; Fattah, Sheik Mohammad Mostakim; Jeong, Kwanghyeon; Chong, Ilyoung; Jeong, Youn-Kwae

2015-01-01

User-centric service features in a Web of Object-enabled Internet of Things environment can be provided by using a semantic ontology that classifies and integrates objects on the World Wide Web as well as shares and merges context-aware information and accumulated knowledge. The semantic ontology is applied on a Web of Object platform to virtualize the real world physical devices and information to form virtual objects that represent the features and capabilities of devices in the virtual world. Detailed information and functionalities of multiple virtual objects are combined with service rules to form composite virtual objects that offer context-aware knowledge-based services, where context awareness plays an important role in enabling automatic modification of the system to reconfigure the services based on the context. Converting the raw data into meaningful information and connecting the information to form the knowledge and storing and reusing the objects in the knowledge base can both be expressed by semantic ontology. In this paper, a knowledge creation model that synchronizes a service logistic model and a virtual world knowledge model on a Web of Object platform has been proposed. To realize the context-aware knowledge-based service creation and execution, a conceptual semantic ontology model has been developed and a prototype has been implemented for a use case scenario of emergency service. PMID:26393609

A User-Centric Knowledge Creation Model in a Web of Object-Enabled Internet of Things Environment.

PubMed

Kibria, Muhammad Golam; Fattah, Sheik Mohammad Mostakim; Jeong, Kwanghyeon; Chong, Ilyoung; Jeong, Youn-Kwae

2015-09-18

User-centric service features in a Web of Object-enabled Internet of Things environment can be provided by using a semantic ontology that classifies and integrates objects on the World Wide Web as well as shares and merges context-aware information and accumulated knowledge. The semantic ontology is applied on a Web of Object platform to virtualize the real world physical devices and information to form virtual objects that represent the features and capabilities of devices in the virtual world. Detailed information and functionalities of multiple virtual objects are combined with service rules to form composite virtual objects that offer context-aware knowledge-based services, where context awareness plays an important role in enabling automatic modification of the system to reconfigure the services based on the context. Converting the raw data into meaningful information and connecting the information to form the knowledge and storing and reusing the objects in the knowledge base can both be expressed by semantic ontology. In this paper, a knowledge creation model that synchronizes a service logistic model and a virtual world knowledge model on a Web of Object platform has been proposed. To realize the context-aware knowledge-based service creation and execution, a conceptual semantic ontology model has been developed and a prototype has been implemented for a use case scenario of emergency service.

Development of a VOR/DME model for an advanced concepts simulator

NASA Technical Reports Server (NTRS)

Steinmetz, G. G.; Bowles, R. L.

1984-01-01

The report presents a definition of a VOR/DME, airborne and ground systems simulation model. This description was drafted in response to a need in the creation of an advanced concepts simulation in which flight station design for the 1980 era can be postulated and examined. The simulation model described herein provides a reasonable representation of VOR/DME station in the continental United States including area coverage by type and noise errors. The detail in which the model has been cast provides the interested researcher with a moderate fidelity level simulator tool for conducting research and evaluation of navigator algorithms. Assumptions made within the development are listed and place certain responsibilities (data bases, communication with other simulation modules, uniform round earth, etc.) upon the researcher.

RAVE: Rapid Visualization Environment

NASA Technical Reports Server (NTRS)

Klumpar, D. M.; Anderson, Kevin; Simoudis, Avangelos

1994-01-01

Visualization is used in the process of analyzing large, multidimensional data sets. However, the selection and creation of visualizations that are appropriate for the characteristics of a particular data set and the satisfaction of the analyst's goals is difficult. The process consists of three tasks that are performed iteratively: generate, test, and refine. The performance of these tasks requires the utilization of several types of domain knowledge that data analysts do not often have. Existing visualization systems and frameworks do not adequately support the performance of these tasks. In this paper we present the RApid Visualization Environment (RAVE), a knowledge-based system that interfaces with commercial visualization frameworks and assists a data analyst in quickly and easily generating, testing, and refining visualizations. RAVE was used for the visualization of in situ measurement data captured by spacecraft.

СЦИНТИЛЛЯЦИОННЫЕ ДЕТЕКТОРЫ УСТАНОВКИ CDF П В ЭКСПЕРИМЕНТАХ ПО ФИЗИКЕ ТЯЖЁЛЫХ КВАРКОВ НА ТЭВА ТРОНЕ (in Russian)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chokheli, Davit

2007-01-01

The author presents the following: 1) Development and creation from scratch of scintillation detectors system for CDF II muon trigger using more than 1140 scintillation counters different type and size; development of the contol and monitoring software/hardware systems; 2) Development and creation of updgraded preshower CPR II for electromagnet calorimeter CDF II with better segmentation by pseydorapidity (10 times more against previous version) to be able collect the data with increased Tevatron luminosity; 3) Aging study for scintillation counters used at CDF II and its long-term efficiency estimation; and 4) Research of the possibility to use the proposed new muon trigger atmore » $$1.0 \\leq \\mu \\leq 1.25$$ region by pseudorapidity by creation of additional layers of muon scintillation detectors.« less

Discontinuous non-equilibrium phase transition in a threshold Schloegl model for autocatalysis: Generic two-phase coexistence and metastability

DOE PAGES

Wang, Chi -Jen; Liu, Da -Jiang; Evans, James W.

2015-04-28

Threshold versions of Schloegl’s model on a lattice, which involve autocatalytic creation and spontaneous annihilation of particles, can provide a simple prototype for discontinuous non-equilibrium phase transitions. These models are equivalent to so-called threshold contact processes. A discontinuous transition between populated and vacuum states can occur selecting a threshold of N ≥ 2 for the minimum number, N, of neighboring particles enabling autocatalytic creation at an empty site. Fundamental open questions remain given the lack of a thermodynamic framework for analysis. For a square lattice with N = 2, we show that phase coexistence occurs not at a unique valuemore » but for a finite range of particle annihilation rate (the natural control parameter). This generic two-phase coexistence also persists when perturbing the model to allow spontaneous particle creation. Such behavior contrasts both the Gibbs phase rule for thermodynamic systems and also previous analysis for this model. We find metastability near the transition corresponding to a non-zero effective line tension, also contrasting previously suggested critical behavior. As a result, mean-field type analysis, extended to treat spatially heterogeneous states, further elucidates model behavior.« less

Discontinuous non-equilibrium phase transition in a threshold Schloegl model for autocatalysis: Generic two-phase coexistence and metastability

NASA Astrophysics Data System (ADS)

Wang, Chi-Jen; Liu, Da-Jiang; Evans, James W.

2015-04-01

Threshold versions of Schloegl's model on a lattice, which involve autocatalytic creation and spontaneous annihilation of particles, can provide a simple prototype for discontinuous non-equilibrium phase transitions. These models are equivalent to so-called threshold contact processes. A discontinuous transition between populated and vacuum states can occur selecting a threshold of N ≥ 2 for the minimum number, N, of neighboring particles enabling autocatalytic creation at an empty site. Fundamental open questions remain given the lack of a thermodynamic framework for analysis. For a square lattice with N = 2, we show that phase coexistence occurs not at a unique value but for a finite range of particle annihilation rate (the natural control parameter). This generic two-phase coexistence also persists when perturbing the model to allow spontaneous particle creation. Such behavior contrasts both the Gibbs phase rule for thermodynamic systems and also previous analysis for this model. We find metastability near the transition corresponding to a non-zero effective line tension, also contrasting previously suggested critical behavior. Mean-field type analysis, extended to treat spatially heterogeneous states, further elucidates model behavior.

Eye Movements during Art Appreciation by Students Taking a Photo Creation Course.

PubMed

Ishiguro, Chiaki; Yokosawa, Kazuhiko; Okada, Takeshi

2016-01-01

Previous studies have focused on the differences in the art appreciation process between individuals, and indicated that novice viewers of artworks, in comparison to experts, rarely consider the creation process of the artwork or how this may relate to style. However, behavioral changes in individuals after educational interventions have not been examined. Art education researchers claim that technical knowledge and creation experiences help novice viewers to pay attention to technical features of artwork. Therefore, an artistic photo creation course was designed and conducted to help students acquire techniques and procedural knowledge of photo creation. The present study verified whether students' viewing strategies during appreciation of photographs changed after the course. Twenty-one students participated in two sessions, viewing the same 12 photographs before and after the course. Based on the analysis of recorded eye movements, the results indicated that the students' perceptual exploration became more active with photographs containing recognizable subjects (i.e., humans and objects), and their global saccades increased when they viewed classic photography, one of the categories of photography covered in the course. Interview data after the course indicated that students became aware of the technical effects in photographs. These results suggest that students' viewing strategies may change following a course, as assessed by behavioral measures of eye movements. Further examination is needed to validate this approach to educational effect measurement.

Eye Movements during Art Appreciation by Students Taking a Photo Creation Course

PubMed Central

Ishiguro, Chiaki; Yokosawa, Kazuhiko; Okada, Takeshi

2016-01-01

Previous studies have focused on the differences in the art appreciation process between individuals, and indicated that novice viewers of artworks, in comparison to experts, rarely consider the creation process of the artwork or how this may relate to style. However, behavioral changes in individuals after educational interventions have not been examined. Art education researchers claim that technical knowledge and creation experiences help novice viewers to pay attention to technical features of artwork. Therefore, an artistic photo creation course was designed and conducted to help students acquire techniques and procedural knowledge of photo creation. The present study verified whether students' viewing strategies during appreciation of photographs changed after the course. Twenty-one students participated in two sessions, viewing the same 12 photographs before and after the course. Based on the analysis of recorded eye movements, the results indicated that the students' perceptual exploration became more active with photographs containing recognizable subjects (i.e., humans and objects), and their global saccades increased when they viewed classic photography, one of the categories of photography covered in the course. Interview data after the course indicated that students became aware of the technical effects in photographs. These results suggest that students' viewing strategies may change following a course, as assessed by behavioral measures of eye movements. Further examination is needed to validate this approach to educational effect measurement. PMID:27471485

MultiDrizzle: An Integrated Pyraf Script for Registering, Cleaning and Combining Images

NASA Astrophysics Data System (ADS)

Koekemoer, A. M.; Fruchter, A. S.; Hook, R. N.; Hack, W.

We present the new PyRAF-based `MultiDrizzle' script, which is aimed at providing a one-step approach to combining dithered HST images. The purpose of this script is to allow easy interaction with the complex suite of tasks in the IRAF/STSDAS `dither' package, as well as the new `PyDrizzle' task, while at the same time retaining the flexibility of these tasks through a number of parameters. These parameters control the various individual steps, such as sky subtraction, image registration, `drizzling' onto separate output images, creation of a clean median image, transformation of the median with `blot' and creation of cosmic ray masks, as well as the final image combination step using `drizzle'. The default parameters of all the steps are set so that the task will work automatically for a wide variety of different types of images, while at the same time allowing adjustment of individual parameters for special cases. The script currently works for both ACS and WFPC2 data, and is now being tested on STIS and NICMOS images. We describe the operation of the script and the effect of various parameters, particularly in the context of combining images from dithered observations using ACS and WFPC2. Additional information is also available at the `MultiDrizzle' home page: http://www.stsci.edu/~koekemoe/multidrizzle/

A multi-criteria targeting approach to neutral grassland conservation.

PubMed

Bayliss, Julian; Helyar, Alice; Lee, John T; Thompson, Stewart

2003-02-01

Resources for creating and managing rare habitats are limited, and a targeting approach aimed at identifying the most viable sites for habitat conservation is therefore desirable. This study developed a multi-criteria targeting approach to site conservation for two rare grassland types, based on a suite of biotic and abiotic factors managed within a Geographical Information System. A number of biotic and abiotic criteria were assessed to evaluate the biodiversity status of grassland sites. Biotic factors included species diversity, species richness and species rarity; and abiotic factors included patch area, position in the ecological unit and the influence of surrounding land use. Each criterion was given equal weighting and a final biodiversity value for each patch was calculated; the patch with the highest cumulative rank score was deemed the patch with the greatest biodiversity. Each site was then examined in relation to agricultural land under the existing management prescriptions of the Upper Thames Tributaries Environmentally Sensitive Area (UTTESA). Sites identified with high biodiversity potential, but currently not included under management prescriptions, were targeted for future inclusion in the ESA scheme. The targeting approach demonstrated how the national Lowland Meadows habitat action plan creation target of 500 ha could be achieved in the UTTESA. The fact that this target figure was so easily attained within this study area highlighted the possible underestimation of national habitat creation targets.

Practical approaches to adverse outcome pathway (AOP) ...

EPA Pesticide Factsheets

Adverse Outcome Pathways (AOPs) describe toxicant effects as a sequential chain of causally linked events beginning with a molecular perturbation and culminating in an adverse outcome at an individual or population level. Strategies for developing AOPs are still evolving and depend largely on the intended use or motivation for development. Four ecological AOP case studies, which were developed for different purposes, are described herein. In each situation, creation of the AOP began in a manner determined by the initial motivation for its creation, and expanded either to include additional components of the pathway, or to address the domains of applicability in terms of chemical initiators, susceptible species, life stages, etc. From these case studies, some general strategies can be gleaned which a developer may find useful for supporting an existing AOP or creating a new one. Several web-based tools which can aid in AOP assembly, as well as evaluation of weight of evidence for scientific robustness of AOP components are highlighted. The need for AOP development and greater population of AOPs in the online knowledgebase has been widely recognized (e.g., OECD Project 1.29, Knapen et al 2015, Escher et al 2016; Groh et al 2015), but currently there are few AOP developers. To promote broader development of AOPs, and the inclusion of potential developers across various types of institutes and fields of study, this manuscript outlines strategies for initiating

New method of a "point-like" neutron source creation based on sharp focusing of high-current deuteron beam onto deuterium-saturated target for neutron tomography

NASA Astrophysics Data System (ADS)

Golubev, S.; Skalyga, V.; Izotov, I.; Sidorov, A.

2017-02-01

A possibility of a compact powerful point-like neutron source creation is discussed. Neutron yield of the source based on deuterium-deuterium (D-D) reaction is estimated at the level of 1011 s-1 (1013 s-1 for deuterium-tritium reaction). The fusion takes place due to bombardment of deuterium- (or tritium) loaded target by high-current focused deuterium ion beam with energy of 100 keV. The ion beam is formed by means of high-current quasi-gasdynamic ion source of a new generation based on an electron cyclotron resonance (ECR) discharge in an open magnetic trap sustained by powerful microwave radiation. The prospects of proposed generator for neutron tomography are discussed. Suggested method is compared to the point-like neutron sources based on a spark produced by powerful femtosecond laser pulses.

Designing an Online Social Support Platform Through Co-Creation with Seniors.

PubMed

Rochat, Jessica; Nap, Henk Herman; Ricci, Arnaud; Cornelisse, Lotte; Lukkien, Dirk; Lovis, Christian; Ehrler, Frédéric

2018-01-01

The high number of seniors that feels excluded of society highlights the necessity to promote active ageing. This intention can be supported through online platforms that encourage participation in social activities. The goal of the present study was to identify design principles of online support platforms for seniors through focus groups and to ideate the platform through co-creation sessions. The results show that a social platform for seniors must, among other, help to foster contact between users, and must provide services and meaningful activities. A first mock-up of the platform's design has been created based on the co-creation sessions and will be iteratively evaluated and enhanced in future studies in four countries across Europe. Our findings are in line with those of other studies demonstrating that seniors attach importance to trustworthiness and need to maintain social ties.

Pillars of Creation Revealed in 3-D

NASA Image and Video Library

2015-05-01

This video clip shows a visualisation of the three-dimensional structure of the Pillars of Creation within the star formation region Messier 16 (also called the Eagle Nebula). It is based on new observations of the object using the MUSE instrument on ESO’s Very Large Telescope in Chile. The pillars actually consist of several distinct pieces on either side of the star cluster NGC 6611. Credit: ESO/M. Kornmesser Read more: www.nasa.gov/image-feature/goddard/pillars-of-creation-re... NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram

Non-destructive evaluation of laboratory scale hydraulic fracturing using acoustic emission

NASA Astrophysics Data System (ADS)

Hampton, Jesse Clay

The primary objective of this research is to develop techniques to characterize hydraulic fractures and fracturing processes using acoustic emission monitoring based on laboratory scale hydraulic fracturing experiments. Individual microcrack AE source characterization is performed to understand the failure mechanisms associated with small failures along pre-existing discontinuities and grain boundaries. Individual microcrack analysis methods include moment tensor inversion techniques to elucidate the mode of failure, crack slip and crack normal direction vectors, and relative volumetric deformation of an individual microcrack. Differentiation between individual microcrack analysis and AE cloud based techniques is studied in efforts to refine discrete fracture network (DFN) creation and regional damage quantification of densely fractured media. Regional damage estimations from combinations of individual microcrack analyses and AE cloud density plotting are used to investigate the usefulness of weighting cloud based AE analysis techniques with microcrack source data. Two granite types were used in several sample configurations including multi-block systems. Laboratory hydraulic fracturing was performed with sample sizes ranging from 15 x 15 x 25 cm3 to 30 x 30 x 25 cm 3 in both unconfined and true-triaxially confined stress states using different types of materials. Hydraulic fracture testing in rock block systems containing a large natural fracture was investigated in terms of AE response throughout fracture interactions. Investigations of differing scale analyses showed the usefulness of individual microcrack characterization as well as DFN and cloud based techniques. Individual microcrack characterization weighting cloud based techniques correlated well with post-test damage evaluations.

TALENT-ed and TYPE III: An Effective Learning Strategy for Gifted Students Who Are Learning Disabled

ERIC Educational Resources Information Center

Newman, Jane L.; Zupko, Sue

2006-01-01

Educators agree that a student can display gifted behavior and learning disabilities (GLD) simultaneously. Some of these students thrive when exploring advanced level investigative projects which require higher order thinking skills (HOTS) and creation of an original product. This article presents a GLD case story as an example of successful…

Languages for Specific Purposes Curriculum Creation and Implementation in Service to the U.S. Community

ERIC Educational Resources Information Center

Lear, Darcy

2012-01-01

Community service learning (CSL) is a type of experiential learning that blends specific course content with real-world applications and ties them together through structured reflection. It is an ideal pedagogy for 21st-century language for specific purposes (LSP) programs. This article frames that argument around sociocultural theory, moves to a…

Where Did Your Graduate Students End Up? LinkedIn Knows

ERIC Educational Resources Information Center

Patton, Stacey

2012-01-01

Stakeholders want to know whether the graduates remained in the states where they got their professional science master's (PSM) degree, what their job titles were, and the type of employers they were working for. Business leaders, governors, and university-system heads want to know if graduates are contributing to job creation and work-force…

Analyzing Forces on Amusement Park Rides with Mobile Devices

ERIC Educational Resources Information Center

Vieyra, Rebecca E.; Vieyra, Chrystian

2014-01-01

Mobile device accelerometers are a simple and easy way for students to collect accurate and detailed data on an amusement park ride. The resulting data can be graphed to assist in the creation of force diagrams to help students explain their physical sensations while on the ride. This type of activity can help students overcome some of the…

Global Learning and Development as an Engagement Strategy for Christian Higher Education: A Macro Study

ERIC Educational Resources Information Center

Decker, Allyn; Hawkins, Greg

2016-01-01

The purpose of this research was to better understand the variety of student and faculty global learning and development programs by member institutions of the Council for Christian Colleges & Universities (CCCU), and what motivated the creation of these types of programs. Although various forms of global engagement programming were examined,…

Value Types in Higher Education--Students' Perspective

ERIC Educational Resources Information Center

Dziewanowska, Katarzyna

2017-01-01

The purpose of the paper is to propose the service-dominant logic in marketing as a framework for analysing the value co-creation process in the higher education sector and present the results of a quantitative study (a survey) conducted among business students from four Polish public universities. The results of the study led to identification of…

The Mechanics of Social Capital and Academic Performance in an Indian College

ERIC Educational Resources Information Center

Hasan, Sharique; Bagde, Surendrakumar

2013-01-01

In this article we examine how social capital affects the creation of human capital. Specifically, we study how college students' peers affect academic performance. Building on existing research, we consider the different types of peers in the academic context and the various mechanisms through which peers affect performance. We test our model…

Self-Efficacy Perceptions of Prospective Social Studies Teachers in Relation to History Teaching

ERIC Educational Resources Information Center

Yilmaz, Ali

2009-01-01

Self-efficacy is one of the important concepts of the social cognitive theory, and can be defined as individual's perception of his or her own capabilities for organizing and successfully executing the courses of action required to attain designated types of performance. Teachers with high self-efficacy perception can contribute to creation of a…

Database Software for Social Studies. A MicroSIFT Quarterly Report.

ERIC Educational Resources Information Center

Weaver, Dave

The report describes and evaluates the use of a set of learning tools called database managers and their creation of databases to help teach problem solving skills in social studies. Details include the design, building, and use of databases in a social studies setting, along with advantages and disadvantages of using them. The three types of…

Modeling as a Core Component of Structuring Data

ERIC Educational Resources Information Center

Konold, Clifford; Finzer, William; Kreetong, Kosoom

2017-01-01

We gave participants diagrams of traffic on two roads with information about eight attributes, including the type of each vehicle, its speed, direction and the width of the road. Their task was to record and organize the data to assist city planners in its analysis. Successfully encoding the information required the creation of a case, a physical…

FOCIH: Form-Based Ontology Creation and Information Harvesting

NASA Astrophysics Data System (ADS)

Tao, Cui; Embley, David W.; Liddle, Stephen W.

Creating an ontology and populating it with data are both labor-intensive tasks requiring a high degree of expertise. Thus, scaling ontology creation and population to the size of the web in an effort to create a web of data—which some see as Web 3.0—is prohibitive. Can we find ways to streamline these tasks and lower the barrier enough to enable Web 3.0? Toward this end we offer a form-based approach to ontology creation that provides a way to create Web 3.0 ontologies without the need for specialized training. And we offer a way to semi-automatically harvest data from the current web of pages for a Web 3.0 ontology. In addition to harvesting information with respect to an ontology, the approach also annotates web pages and links facts in web pages to ontological concepts, resulting in a web of data superimposed over the web of pages. Experience with our prototype system shows that mappings between conceptual-model-based ontologies and forms are sufficient for creating the kind of ontologies needed for Web 3.0, and experiments with our prototype system show that automatic harvesting, automatic annotation, and automatic superimposition of a web of data over a web of pages work well.

Technology and Current Reading/Literacy Assessment Strategies

ERIC Educational Resources Information Center

Balajthy, Ernest

2007-01-01

Computer-based technologies offer promise as a means to assess students and provide teachers with better understandings of their students' achievement. This article describes recent developments in computer-based and web-based reading and literacy assessment, focusing on assessment administration, information management, and report creation. In…

Does physics instruction foster university students' cognitive processes?: A descriptive study of teacher activities

NASA Astrophysics Data System (ADS)

Ferguson-Hessler, Monica G. M.; de Jong, Ton

This study aims at giving a systematic description of the cognitive activities involved in teaching physics. Such a description of instruction in physics requires a basis in two models, that is, the cognitive activities involved in learning physics and the knowledge base that is the foundation of expertise in that subject. These models have been provided by earlier research. The model of instruction distinguishes three main categories of instruction process: presenting new information, integrating (i.e., bringing structure into) new knowledge, and connecting elements of new knowledge to prior knowledge. Each of the main categories has been divided into a number of specific instruction processes. Hereby any limited and specific cognitive teacher activity can be described along the two dimensions of process and type of knowledge. The model was validated by application to lectures and problem-solving classes of first year university courses. These were recorded and analyzed as to instruction process and type of knowledge. Results indicate that teachers are indeed involved in the various types of instruction processes defined. The importance of this study lies in the creation of a terminology that makes it possible to discuss instruction in an explicit and specific way.

Analysis of mutual assured destruction-like scenario with swarms of non-recallable autonomous robots

NASA Astrophysics Data System (ADS)

Straub, Jeremy

2015-05-01

This paper considers the implications of the creation of an autonomous robotic fighting force without recall-ability which could serve as a deterrent to a `total war' magnitude attack. It discusses the technical considerations for this type of robotic system and the limited enhancements required to current technologies (particularly UAVs) needed to create such a system. Particular consideration is paid to how the introduction of this type of technology by one actor could create a need for reciprocal development. Also considered is the prospective utilization of this type of technology by non-state actors and the impact of this on state actors.

Predictors of nonfunctional arteriovenous access at hemodialysis initiation and timing of access creation: A registry-based study

PubMed Central

Metzger, Marie; Labeeuw, Michel; Ayav, Carole; Jacquelinet, Christian; Massy, Ziad A.; Stengel, Bénédicte

2017-01-01

Determinants of nonfunctional arteriovenous (AV) access, including timing of AV access creation, have not been sufficiently described. We studied 29 945 patients who had predialysis AV access placement and were included in the French REIN registry from 2005 through 2013. AV access was considered nonfunctional when dialysis began with a catheter. We estimated crude and adjusted odds ratio (OR) with 95% confidence intervals (CI) of nonfunctional versus functional AV access associated with case-mix, facility characteristics, and timing of AV access creation. Analyses were stratified by dialysis start condition (planned or as an emergency) and comorbidity profile. Overall, 18% patients had nonfunctional AV access at hemodialysis initiation. In the group with planned dialysis start, female gender (OR 1.43, 95% CI 1.32–1.56), diabetes (OR 1.28, 95% CI 1.15–1.44), and a higher number of cardiovascular comorbidities (OR 1.27, 95% CI 1.09–1.49, and 1.31, 1.05–1.64, for 3 and >3 cardiovascular comorbidities versus none, respectively) were independent predictors of nonfunctional AV access. A higher percentage of AV access creation at the region level was associated with a lower rate of nonfunctional AV access (OR 0.98, 95% CI 0.98–0.99 per 1% increase). The odds of nonfunctional AV access decreased as time from creation to hemodialysis initiation increased up to 3 months in nondiabetic patients with fewer than 2 cardiovascular comorbidities and 6 months in patients with diabetes or 2 or more such comorbidities. In conclusion, both patient characteristics and clinical practices may play a role in successful AV access use at hemodialysis initiation. Adjusting the timing of AV access creation to patients’ comorbidity profiles may improve functional AV access rates. PMID:28749967

Predictors of nonfunctional arteriovenous access at hemodialysis initiation and timing of access creation: A registry-based study.

PubMed

Alencar de Pinho, Natalia; Coscas, Raphael; Metzger, Marie; Labeeuw, Michel; Ayav, Carole; Jacquelinet, Christian; Massy, Ziad A; Stengel, Bénédicte

2017-01-01

Determinants of nonfunctional arteriovenous (AV) access, including timing of AV access creation, have not been sufficiently described. We studied 29 945 patients who had predialysis AV access placement and were included in the French REIN registry from 2005 through 2013. AV access was considered nonfunctional when dialysis began with a catheter. We estimated crude and adjusted odds ratio (OR) with 95% confidence intervals (CI) of nonfunctional versus functional AV access associated with case-mix, facility characteristics, and timing of AV access creation. Analyses were stratified by dialysis start condition (planned or as an emergency) and comorbidity profile. Overall, 18% patients had nonfunctional AV access at hemodialysis initiation. In the group with planned dialysis start, female gender (OR 1.43, 95% CI 1.32-1.56), diabetes (OR 1.28, 95% CI 1.15-1.44), and a higher number of cardiovascular comorbidities (OR 1.27, 95% CI 1.09-1.49, and 1.31, 1.05-1.64, for 3 and >3 cardiovascular comorbidities versus none, respectively) were independent predictors of nonfunctional AV access. A higher percentage of AV access creation at the region level was associated with a lower rate of nonfunctional AV access (OR 0.98, 95% CI 0.98-0.99 per 1% increase). The odds of nonfunctional AV access decreased as time from creation to hemodialysis initiation increased up to 3 months in nondiabetic patients with fewer than 2 cardiovascular comorbidities and 6 months in patients with diabetes or 2 or more such comorbidities. In conclusion, both patient characteristics and clinical practices may play a role in successful AV access use at hemodialysis initiation. Adjusting the timing of AV access creation to patients' comorbidity profiles may improve functional AV access rates.

Point clouds segmentation as base for as-built BIM creation

NASA Astrophysics Data System (ADS)

Macher, H.; Landes, T.; Grussenmeyer, P.

2015-08-01

In this paper, a three steps segmentation approach is proposed in order to create 3D models from point clouds acquired by TLS inside buildings. The three scales of segmentation are floors, rooms and planes composing the rooms. First, floor segmentation is performed based on analysis of point distribution along Z axis. Then, for each floor, room segmentation is achieved considering a slice of point cloud at ceiling level. Finally, planes are segmented for each room, and planes corresponding to ceilings and floors are identified. Results of each step are analysed and potential improvements are proposed. Based on segmented point clouds, the creation of as-built BIM is considered in a future work section. Not only the classification of planes into several categories is proposed, but the potential use of point clouds acquired outside buildings is also considered.

Stochastic Process Creation

NASA Astrophysics Data System (ADS)

Esparza, Javier

In many areas of computer science entities can “reproduce”, “replicate”, or “create new instances”. Paramount examples are threads in multithreaded programs, processes in operating systems, and computer viruses, but many others exist: procedure calls create new incarnations of the callees, web crawlers discover new pages to be explored (and so “create” new tasks), divide-and-conquer procedures split a problem into subproblems, and leaves of tree-based data structures become internal nodes with children. For lack of a better name, I use the generic term systems with process creation to refer to all these entities.

A Framework for the Design of Service Systems

NASA Astrophysics Data System (ADS)

Tan, Yao-Hua; Hofman, Wout; Gordijn, Jaap; Hulstijn, Joris

We propose a framework for the design and implementation of service systems, especially to design controls for long-term sustainable value co-creation. The framework is based on the software support tool e3-control. To illustrate the framework we use a large-scale case study, the Beer Living Lab, for simplification of customs procedures in international trade. The BeerLL shows how value co-creation can be achieved by reduction of administrative burden in international beer export due to electronic customs. Participants in the BeerLL are Heineken, IBM and Dutch Tax & Customs.

Bell pair creation in current of Kondo-correlated dot

NASA Astrophysics Data System (ADS)

Sakano, Rui; Oguri, Akira; Nishikawa, Yunori; Abe, Eisuke

Recently, local-Fermi-liquid properties in non-linear currents and shot noises through the Kondo dot have been investigated both theoretically and experimentally. We suggest a new entangled-electron-pair generator utilizing mechanism of quasiparticle-pair creation which has been observed as enhancement of shot noise in the quantum dot. Using the renormalized perturbation theory for an orbital-degenerate impurity Anderson model and the full counting statistics, we calculate the Clauser-Horne-Shimony-Holt type Bell's correlator for currents through correlated two different channels of a Kondo correlated dot. It is shown that residual exchange-interactions of the local-Fermi-liquid create spin-entangled quasiparticle-pairs in nonlinear current and this results in violation of the Bell's inequality. This work was partially supported by JSPS KAKENHI Grant Numbers JP26220711, JP26400319, JP15K05181 and JP16K17723.

Achieving behavioral control with millisecond resolution in a high-level programming environment.

PubMed

Asaad, Wael F; Eskandar, Emad N

2008-08-30

The creation of psychophysical tasks for the behavioral neurosciences has generally relied upon low-level software running on a limited range of hardware. Despite the availability of software that allows the coding of behavioral tasks in high-level programming environments, many researchers are still reluctant to trust the temporal accuracy and resolution of programs running in such environments, especially when they run atop non-real-time operating systems. Thus, the creation of behavioral paradigms has been slowed by the intricacy of the coding required and their dissemination across labs has been hampered by the various types of hardware needed. However, we demonstrate here that, when proper measures are taken to handle the various sources of temporal error, accuracy can be achieved at the 1 ms time-scale that is relevant for the alignment of behavioral and neural events.

Continental crustal formation and recycling: Evidence from oceanic basalts

NASA Technical Reports Server (NTRS)

Saunders, A. D.; Tarney, J.; Norry, M. J.

1988-01-01

Despite the wealth of geochemical data for subduction-related magma types, and the clear importance of such magmas in the creation of continental crust, there is still no concensus about the relative magnitudes of crustal creation versus crustal destruction (i.e., recycling of crust into the mantle). The role of subducted sediment in the formation of the arc magmas is now well documented; but what proportion of sediment is taken into the deeper mantle? Integrated isotopic and trace element studies of magmas erupted far from presently active subduction zones, in particular basaltic rocks erupted in the ocean basins, are providing important information about the role of crustal recycling. By identifying potential chemical tracers, it is impossible to monitor the effects of crustal recycling, and produce models predicting the mass of material recycled into the mantle throughout long periods of geological time.

Grassland birds: An overview of threats and recommended management strategies

USGS Publications Warehouse

Vickery, P.D.; Herkert, J.R.; Knopf, F.L.; Ruth, J.; Keller, C.E.; Bonney, Rick; Pashley, David N.; Cooper, Robert; Niles, Larry

2000-01-01

Grassland ecosystems are dependent on periodic disturbance for habitat maintenance. Historically, grazing by native herbivores and prairie fires were the agents principally responsible for maintaining grassland areas. However, elimination of native herbivores, wide-spread fire suppression, and conversion for agriculture have greatly altered grasslands in the United States and Canada. Because of these landscape changes, many grassland birds are increasingly dependent on land managers for habitat creation, maintenance, and health. Grazing, prescribed burning, and mowing/haying are the most frequently used, and versatile, grassland management techniques. Grassland birds prefer a wide range of grass heights and densities, with some species preferring short sparse vegetation, and others preferring taller, more dense vegetation. Due to differences in species habitat preferences and regional differences in soils and floristics, the responses of individual grassland species to specific grassland management practices can be variable and often are regionally dependent. As a result, management of grassland areas is best directed toward the creation of a mosaic of grassland habitat types. This habitat mosaic is probably best maintained through some type of rotational management system in which sections of large grassland areas receive management on a regular schedule. Such a rotational system would provide a variety of habitat types in every year, would ensure the availability of suitable habitat for birds at either end of the grassland management spectrum, and also would provide habitat for birds whose preferences lie between these extremes.

“I Got to Know Them in a New Way”: Rela(y/t)ing Rhizomes and Community-Based Knowledge (Brokers’) Transformation of Western and Indigenous Knowledge

PubMed Central

Fornssler, Barbara; McKenzie, Holly A.; Dell, Colleen Anne; Laliberte, Larry; Hopkins, Carol

2016-01-01

Drawing on three culturally specific research projects, this paper examines how community-based knowledge brokers’ engagement in brokering knowledge shaped the projects’ processes. Informed by Deleuze and Guattari’s (1987) conceptualization of the “rhizome,” we discuss how community knowledge brokers’ engagement in open research-creation practices embrace the relational foundation of Indigenous research paradigms in contrast to mainstream Western research practices that are engaged as linear, objective, and outcome-oriented activities. In turn, we offer propositions for building team environments where open research-creation practices can unfold, informing a periphery of shared space for Indigenous and Western paradigms. PMID:27867319

Promotion of Evidence-Based Nursing by Polish and foreign nursing organizations.

PubMed

Wasowska, Iga; Repka, Iwona

2014-01-01

The aim of the review was to obtain information on specific activities undertaken by professional nursing organizations, in order to promote and develop Evidence-Based Nursing (EBN). The foreign organizations featured in the study actively promote EBN within their countries of origin. This activity is currently focused on the structural and financial measures (focused on extrinsic factors). Some organizations are lobbying governments for grants and general support, in order to further their use and development of EBN. Educational activities are still ongoing, which include the creation of the creation of new guidelines and publishing research in journals, along with the organization of periodic conferences. Polish Nurses Association was the only one not involved in any structural and financial activities.

Professor Tyndale John Rendle-Short (1919-2010), British and Australian paediatrician: A life in two domains.

PubMed

Pearn, John

2014-05-01

Professor Tyndale John Rendle-Short (1919-2010), a British and Australian paediatrician, lived a professional life of considerable influence in two domains - academic paediatrics and fundamentalist theology. A Cambridge medical graduate (1943) and doctor-soldier, he was appointed as the Foundation Professor of Child Health at the University of Queensland (1961). In Australia, he was a pioneer in three paediatric developments ('rooming-in' for mothers in hospitals, autism research and cystic fibrosis). His A Synopsis of Children's Diseases was published in six editions, was translated into three languages and was used as a standard paediatric textbook on four Continents. Distinct from this clinical domain, as a passionate anti-Darwinist his fundamentalist theology was that variously self-described as 'theistic evolution' (believing in 'progressive Creationism') and later that of 'six-literal day young-earth Creation'. He established and was the Foundation Chairman of the Creation Science Foundation (UK) and was World Chairman of the US-based Creation Ministries International. This biography is a record of this perhaps paradoxical and unique life. © The Author(s) 2013 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav.

Literature-Based Scientific Learning: A Collaboration Model

ERIC Educational Resources Information Center

Elrod, Susan L.; Somerville, Mary M.

2007-01-01

Amidst exponential growth of knowledge, student insights into the knowledge creation practices of the scientific community can be furthered by science faculty collaborations with university librarians. The Literature-Based Scientific Learning model advances undergraduates' disciplinary mastery and information literacy through experience with…

An Overview of Computer-Based Natural Language Processing.

ERIC Educational Resources Information Center

Gevarter, William B.

Computer-based Natural Language Processing (NLP) is the key to enabling humans and their computer-based creations to interact with machines using natural languages (English, Japanese, German, etc.) rather than formal computer languages. NLP is a major research area in the fields of artificial intelligence and computational linguistics. Commercial…

Modeling and prototyping of biometric systems using dataflow programming

NASA Astrophysics Data System (ADS)

Minakova, N.; Petrov, I.

2018-01-01

The development of biometric systems is one of the labor-intensive processes. Therefore, the creation and analysis of approaches and techniques is an urgent task at present. This article presents a technique of modeling and prototyping biometric systems based on dataflow programming. The technique includes three main stages: the development of functional blocks, the creation of a dataflow graph and the generation of a prototype. A specially developed software modeling environment that implements this technique is described. As an example of the use of this technique, an example of the implementation of the iris localization subsystem is demonstrated. A variant of modification of dataflow programming is suggested to solve the problem related to the undefined order of block activation. The main advantage of the presented technique is the ability to visually display and design the model of the biometric system, the rapid creation of a working prototype and the reuse of the previously developed functional blocks.

The co-creation of meaningful action: bridging enaction and interactional sociology.

PubMed

De Jaegher, Hanne; Peräkylä, Anssi; Stevanovic, Melisa

2016-05-05

What makes possible the co-creation of meaningful action? In this paper, we go in search of an answer to this question by combining insights from interactional sociology and enaction. Both research schools investigate social interactions as such, and conceptualize their organization in terms of autonomy. We ask what it could mean for an interaction to be autonomous, and discuss the structures and processes that contribute to and are maintained in the so-called interaction order. We also discuss the role played by individual vulnerability as well as the vulnerability of social interaction processes in the co-creation of meaningful action. Finally, we outline some implications of this interdisciplinary fraternization for the empirical study of social understanding, in particular in social neuroscience and psychology, pointing out the need for studies based on dynamic systems approaches on origins and references of coordination, and experimental designs to help understand human co-presence. © 2016 The Authors.

The co-creation of meaningful action: bridging enaction and interactional sociology

PubMed Central

Peräkylä, Anssi; Stevanovic, Melisa

2016-01-01

What makes possible the co-creation of meaningful action? In this paper, we go in search of an answer to this question by combining insights from interactional sociology and enaction. Both research schools investigate social interactions as such, and conceptualize their organization in terms of autonomy. We ask what it could mean for an interaction to be autonomous, and discuss the structures and processes that contribute to and are maintained in the so-called interaction order. We also discuss the role played by individual vulnerability as well as the vulnerability of social interaction processes in the co-creation of meaningful action. Finally, we outline some implications of this interdisciplinary fraternization for the empirical study of social understanding, in particular in social neuroscience and psychology, pointing out the need for studies based on dynamic systems approaches on origins and references of coordination, and experimental designs to help understand human co-presence. PMID:27069055

Parastomal hernia – current knowledge and treatment

PubMed Central

Styliński, Roman; Rudzki, Sławomir

2018-01-01

Intestinal stoma creation is one of the most common surgical procedures. The most common long-term complication following stoma creation is parastomal hernia, which according to some authors is practically unavoidable. Statistical differences of its occurrence are mainly due to patient observation time and evaluation criteria. Consequently, primary prevention methods such as placement of prosthetic mesh and newly developed minimally invasive methods of stoma creation are used. It seems that in the light of evidence-based medicine, the best way to treat parastomal hernia is the one that the surgeon undertaking therapy is the most experienced in and is suited to the individuality of each patient, his condition and comorbidities. As a general rule, reinforcing the abdominal wall with a prosthetic mesh is the treatment of choice, with a low rate of complications and relapses over a long period of time. The current trend is to use lightweight, large pore meshes. PMID:29643952

Pea weevil damage and chemical characteristics of pea cultivars determining their resistance to Bruchus pisorum L.

PubMed

Nikolova, I

2016-04-01

Bruchus pisorum (L.) is one of the most intractable pest problems of cultivated pea in Europe. Development of resistant cultivars is very important to environmental protection and would solve this problem to a great extent. Therefore, the resistance of five spring pea cultivars was studied to B. pisorum: Glyans, Modus; Kamerton and Svit and Pleven 4 based on the weevil damage and chemical composition of seeds. The seeds were classified as three types: healthy seeds (type one), damaged seeds with parasitoid emergence holes (type two) and damaged seeds with bruchid emergence holes (type three). From visibly damaged pea seeds by pea weevil B. pisorum was isolated the parasitoid Triaspis thoracica Curtis (Hymenoptera, Braconidae). Modus, followed by Glyans was outlined as resistant cultivars against the pea weevil. They had the lowest total damaged seed degree, loss in weight of damaged seeds (type two and type three) and values of susceptibility coefficients. A strong negative relationship (r = -0.838) between the weight of type one seeds and the proportion of type three seeds was found. Cultivars with lower protein and phosphorus (P) content had a lower level of damage. The crude protein, crude fiber and P content in damaged seeds significantly or no significantly were increased as compared with the healthy seeds due to weevil damage. The P content had the highest significant influence on pea weevil infestation. Use of chemical markers for resistance to the creation of new pea cultivars can be effective method for defense and control against B. pisorum.

Reclassification of Paenibacillus riograndensis as a Genomovar of Paenibacillus sonchi: Genome-Based Metrics Improve Bacterial Taxonomic Classification

PubMed Central

Sant’Anna, Fernando H.; Ambrosini, Adriana; de Souza, Rocheli; de Carvalho Fernandes, Gabriela; Bach, Evelise; Balsanelli, Eduardo; Baura, Valter; Brito, Luciana F.; Wendisch, Volker F.; de Oliveira Pedrosa, Fábio; de Souza, Emanuel M.; Passaglia, Luciane M. P.

2017-01-01

Species from the genus Paenibacillus are widely studied due to their biotechnological relevance. Dozens of novel species descriptions of this genus were published in the last couple of years, but few utilized genomic data as classification criteria. Here, we demonstrate the importance of using genome-based metrics and phylogenetic analyses to identify and classify Paenibacillus strains. For this purpose, Paenibacillus riograndensis SBR5T, Paenibacillus sonchi X19-5T, and their close relatives were compared through phenotypic, genotypic, and genomic approaches. With respect to P. sonchi X19-5T, P. riograndensis SBR5T, Paenibacillus sp. CAR114, and Paenibacillus sp. CAS34 presented ANI (average nucleotide identity) values ranging from 95.61 to 96.32%, gANI (whole-genome average nucleotide identity) values ranging from 96.78 to 97.31%, and dDDH (digital DNA–DNA hybridization) values ranging from 68.2 to 73.2%. Phylogenetic analyses of 16S rRNA, gyrB, recA, recN, and rpoB genes and concatenated proteins supported the monophyletic origin of these Paenibacillus strains. Therefore, we propose to assign Paenibacillus sp. CAR114 and Paenibacillus sp. CAS34 to P. sonchi species, and reclassify P. riograndensis SBR5T as a later heterotypic synonym of P. sonchi (type strain X19-5T), with the creation of three novel genomovars, P. sonchi genomovar Sonchi (type strain X19-5T), P. sonchi genomovar Riograndensis (type strain SBR5T), P. sonchi genomovar Oryzarum (type strain CAS34T = DSM 102041T; = BR10511T). PMID:29046663

A method for radiological characterization based on fluence conversion coefficients

NASA Astrophysics Data System (ADS)

Froeschl, Robert

2018-06-01

Radiological characterization of components in accelerator environments is often required to ensure adequate radiation protection during maintenance, transport and handling as well as for the selection of the proper disposal pathway. The relevant quantities are typical the weighted sums of specific activities with radionuclide-specific weighting coefficients. Traditional methods based on Monte Carlo simulations are radionuclide creation-event based or the particle fluences in the regions of interest are scored and then off-line weighted with radionuclide production cross sections. The presented method bases the radiological characterization on a set of fluence conversion coefficients. For a given irradiation profile and cool-down time, radionuclide production cross-sections, material composition and radionuclide-specific weighting coefficients, a set of particle type and energy dependent fluence conversion coefficients is computed. These fluence conversion coefficients can then be used in a Monte Carlo transport code to perform on-line weighting to directly obtain the desired radiological characterization, either by using built-in multiplier features such as in the PHITS code or by writing a dedicated user routine such as for the FLUKA code. The presented method has been validated against the standard event-based methods directly available in Monte Carlo transport codes.

Creating Web-Based Scientific Applications Using Java Servlets

NASA Technical Reports Server (NTRS)

Palmer, Grant; Arnold, James O. (Technical Monitor)

2001-01-01

There are many advantages to developing web-based scientific applications. Any number of people can access the application concurrently. The application can be accessed from a remote location. The application becomes essentially platform-independent because it can be run from any machine that has internet access and can run a web browser. Maintenance and upgrades to the application are simplified since only one copy of the application exists in a centralized location. This paper details the creation of web-based applications using Java servlets. Java is a powerful, versatile programming language that is well suited to developing web-based programs. A Java servlet provides the interface between the central server and the remote client machines. The servlet accepts input data from the client, runs the application on the server, and sends the output back to the client machine. The type of servlet that supports the HTTP protocol will be discussed in depth. Among the topics the paper will discuss are how to write an http servlet, how the servlet can run applications written in Java and other languages, and how to set up a Java web server. The entire process will be demonstrated by building a web-based application to compute stagnation point heat transfer.

Overviewing Software Applications for Graphic Novel Creation in the Post-Secondary and Secondary Classroom

ERIC Educational Resources Information Center

Kirchoff, Jeffrey S. J.; Cook, Mike

2015-01-01

It is well established that the 21st century literate student needs to be able to effectively craft and interpret texts that use multiple communicative modes. Graphic novels are one text type that facilitates such literacy instruction, as the seamless relationship between words, image, and sound (in the form of sound effects) are inherent to the…

Wikiwijs: An Unexpected Journey and the Lessons Learned towards OER

ERIC Educational Resources Information Center

Schuwer, Robert; Kreijns, Karel; Vermeulen, Marjan

2014-01-01

The Dutch Ministry of Education, Culture and Science has funded a five years program to encourage the use, creation and sharing of Open Educational Resources (OER) by teachers from various types of education. This program is known as Wikiwijs. Ultimo 2013, the program has come to an end. As some of the assumptions at the start of Wikiwijs proved…

Intimate Geographies: Reclaiming Citizenship and Community in "The Autobiography of Delfina Cuero" and Bonita Nunez's "Diaries"

ERIC Educational Resources Information Center

Fitzgerald, Stephanie

2006-01-01

American Indian women's autobiographies recount a specific type of life experience that has often been overlooked, one that is equally important in understanding the genre and to develop ways of reading these texts that balance the recovery and recognition of the Native voice and agency contained within them with the processes of creation and the…

Adsorption and transport of imazapyr through intact soils columns taken from two soils under two tillage systems

USDA-ARS?s Scientific Manuscript database

Imazapyr (2-(4,5-dihydro-4-methyl-4-(1-methylethyl)-5-oxo-1H-imidazol-2-yl)-3- pyridinecarboxylic acid) is an imidazolinone herbicide used to control a wide spectrum of weed species. It's use has increased since the creation of a new type of nontransgenic imidazolinone resistant sunflower. This herb...

Spanish and English Word-Initial Voiceless Stop Production in Code-Switched vs. Monolingual Structures

ERIC Educational Resources Information Center

Gonzalez Lopez, Veronica

2012-01-01

The present study examines the production outcomes of late second language (L2) learners in order to determine if the mechanisms that allow the creation of phonetic categories remains available during the lifespan, as the Speech Language Model (SLM) claims. In addition, the study focuses on the type of interaction that exists between the first…

Meteorological tsunamis along the U.S. coastline

NASA Astrophysics Data System (ADS)

Vilibic, I.; Monserrat, S.; Amores, A.; Dadic, V.; Fine, I.; Horvath, K.; Ivankovic, D.; Marcos, M.; Mihanovic, H.; Pasquet, S.; Rabinovich, A. B.; Sepic, J.; Strelec Mahovic, N.; Whitmore, P.

2012-04-01

Meteotsunamis, or meteorological tsunamis, are atmospherically induced ocean waves in the tsunami frequency band that are found to affect coasts in a destructive way in a number of places in the World Ocean, including the U.S. coastline. The Boothbay Harbor, Maine, in October 2008 and Daytona Beach, Florida, in July 1992 were hit by several meters high waves appearing from "nowhere", and a preliminary assessment pointed to the atmosphere as a possible source for the events. As a need for in-depth analyses and proper qualification of these and other events emerged, National Oceanographic and Atmospheric Administration (NOAA) decided to fund the research, currently carried out within the TMEWS project (Towards a MEteotsunami Warning System along the U.S. coastline). The project structure, planned research activities and first results will be presented here. The first objective of the project is creation of a list of potential meteotsunami events, from catalogues, news and high-resolution sea level data, and their proper assessment with regards to the source, generation and dynamics. The assessment will be based on the research of the various types of ocean (tide gauges, buoys), atmospheric (ground stations, buoys, vertical soundings, reanalyses) and remote sensing (satellites) data and products, supported by the atmospheric and ocean modelling efforts. Based on the earned knowledge, the basis for a meteotsunami warning system, i.e. observational systems and communication needs for early detection of a meteotsunami, will be defined. Finally, meteotsunami warning protocols, procedures and decision matrix will be developed, and tested on historical meteotsunami events. These deliverables are expected also to boost meteotsunami research in other parts of the World Ocean, and to contribute to the creation of an efficient meteotsunami warning systems in different regions of interest, such as Mediterranean Sea, western Japan, Western Australia or other.

Spatial Object Recognition Enables Endogenous LTD that Curtails LTP in the Mouse Hippocampus

PubMed Central

Goh, Jinzhong Jeremy

2013-01-01

Although synaptic plasticity is believed to comprise the cellular substrate for learning and memory, limited direct evidence exists that hippocampus-dependent learning actually triggers synaptic plasticity. It is likely, however, that long-term potentiation (LTP) works in concert with its counterpart, long-term depression (LTD) in the creation of spatial memory. It has been reported in rats that weak synaptic plasticity is facilitated into persistent plasticity if afferent stimulation is coupled with a novel spatial learning event. It is not known if this phenomenon also occurs in other species. We recorded from the hippocampal CA1 of freely behaving mice and observed that novel spatial learning triggers endogenous LTD. Specifically, we observed that LTD is enabled when test-pulse afferent stimulation is given during the learning of object constellations or during a spatial object recognition task. Intriguingly, LTP is significantly impaired by the same tasks, suggesting that LTD is the main cellular substrate for this type of learning. These data indicate that learning-facilitated plasticity is not exclusive to rats and that spatial learning leads to endogenous LTD in the hippocampus, suggesting an important role for this type of synaptic plasticity in the creation of hippocampus-dependent memory. PMID:22510536

The Ferret as a Surgical Model for Vocal Fold Scar Creation and Treatment.

PubMed

Kodama, Haruka; Kumai, Yoshihiko; Nishimoto, Kohei; Toya, Yutaka; Miyamaru, Satoru; Furushima, Shinobu; Yumoto, Eiji

2018-03-01

To develop a vocal fold (VF) scarring procedure in the ferret, characterize the scars histologically, and test the injectability of the lamina propria (LP). Secondarily, to compare laryngeal anatomy of the ferret with rat and rabbit. The larynges of 18 male ferrets were prepared by unilateral scarring, and normal larynges from 6 female Wistar rats and 5 male albino rabbits were used for comparative purposes. For scarring, the right VF were electrocauterized, ablating the entire LP. Prior to harvesting the larynges at 4 and 16 weeks, each ferret was re-anesthetized, and in 3 animals, India ink was injected into the LPs of both normal and scarred VFs. Laryngoscopic methods and instrumentation for precise visualization, scarring, and injection were developed. The scarred VFs had reduced hyaluronic acid and increased collagen type I, III, and fibronectin compared with normal VFs. The 2 timepoints (4 and 16 weeks) differed significantly only in collagen type III level (levels were higher at 4 weeks). Injected ink migrated from scarred LP to muscle layer just beneath the scarred tissue 3 hours after injection. The ferret is a promising species for creation and experimental treatment of vocal fold scar.

Enabling and sustaining the activities of lay health influencers: lessons from a community-based tobacco cessation intervention study.

PubMed

Castañeda, Heide; Nichter, Mark; Nichter, Mimi; Muramoto, Myra

2010-07-01

The authors present findings from a community-based tobacco cessation project that trained lay health influencers to conduct brief interventions. They outline four major lessons regarding sustainability. First, participants were concerned about the impact that promoting cessation might have on social relationships. "Social risk" must be addressed during training to ensure long-term sustainability. Second, formal training provided participants with an increased sense of self-efficacy, allowed them to embrace a health influencer identity, and aided in further reducing social risk. Third, material resources functioned to mediate social tensions during health intervention conversations. A variety of resources should be made available to health influencers to accommodate type of relationship, timing, and location of the interaction. Finally, project design must be attentive to the creation of a "community of practice" among health influencers as an integral part of project sustainability. These lessons have broad implications for successful health promotion beyond tobacco cessation.

An aspartate and a water molecule mediate efficient acid-base catalysis in a tailored antibody pocket

PubMed Central

Debler, Erik W.; Müller, Roger; Hilvert, Donald; Wilson, Ian A.

2009-01-01

Design of catalysts featuring multiple functional groups is a desirable, yet formidable goal. Antibody 13G5, which accelerates the cleavage of unactivated benzisoxazoles, is one of few artificial enzymes that harness an acid and a base to achieve efficient proton transfer. X-ray structures of the Fab-hapten complexes of wild-type 13G5 and active-site variants now afford detailed insights into its mechanism. The parent antibody preorganizes AspH35 and GluL34 to abstract a proton from substrate and to orient a water molecule for leaving group stabilization, respectively. Remodeling the environment of the hydrogen bond donor with a compensatory network of ordered waters, as seen in the GluL34 to alanine mutant, leads to an impressive 109-fold rate acceleration over the nonenzymatic reaction with acetate, illustrating the utility of buried water molecules in bifunctional catalysis. Generalization of these design principles may aid in creation of catalysts for other important chemical transformations. PMID:19846764

Adapting Comparative Effectiveness Research Summaries for Delivery to Patients and Providers through a Patient Portal

PubMed Central

McDougald Scott, Amanda M.; Jackson, Gretchen Purcell; Ho, Yun-Xian; Yan, Zhou; Davison, Coda; Rosenbloom, S. Trent

2013-01-01

Despite increases in the scientific evidence for a variety of medical treatments, a gap remains in the adoption of best medical practices. This manuscript describes a process for adapting published summary guides from comparative effectiveness research to render them concise, targeted to audience, and easily actionable; and a strategy for disseminating such evidence to patients and their physicians through a web-based portal and linked electronic health record. This project adapted summary guides about oral medications for adults with type 2 diabetes to a fifth-grade literacy level and modified the resulting materials based on evaluations with the Suitability Assessment of Materials instrument. Focus groups and individual interviews with patients, diabetes providers, and health literacy experts were employed to evaluate and enhance the adapted summary guide. We present the lessons learned as general guidelines for the creation of concise, targeted, and actionable evidence and its delivery to both patients and providers through increasingly prevalent health information technologies. PMID:24551387

Radio science ground data system for the Voyager-Neptune encounter, part 1

NASA Technical Reports Server (NTRS)

Kursinski, E. R.; Asmar, S. W.

1991-01-01

The Voyager radio science experiments at Neptune required the creation of a ground data system array that includes a Deep Space Network complex, the Parkes Radio Observatory, and the Usuda deep space tracking station. The performance requirements were based on experience with the previous Voyager encounters, as well as the scientific goals at Neptune. The requirements were stricter than those of the Uranus encounter because of the need to avoid the phase-stability problems experienced during that encounter and because the spacecraft flyby was faster and closer to the planet than previous encounters. The primary requirement on the instrument was to recover the phase and amplitude of the S- and X-band (2.3 and 8.4 GHz) signals under the dynamic conditions encountered during the occultations. The primary receiver type for the measurements was open loop with high phase-noise and frequency stability performance. The receiver filter bandwidth was predetermined based on the spacecraft's trajectory and frequency uncertainties.

Cost-efficiency of knowledge creation: randomized controlled trials vs. observational studies.

PubMed

Struck, Rafael; Baumgarten, Georg; Wittmann, Maria

2014-04-01

This article reviews traditional and current perspectives on randomized, controlled trials (RCTs) and observational studies relative to the economic implications for public healthcare stakeholders. It takes an average of 17 years to bring 14% of original research into clinical practice. Results from high-quality observational studies may complement limited RCTs in primary and secondary literature bases, and enhance the incorporation of sound evidence-based guidelines. Observational findings from comprehensive medical databases may offer valuable clues on the effectiveness and relevance of public healthcare interventions. Major expenditures associated with RCTs relate to recruitment, inappropriate site selection, conduct and reporting. Application of business strategies and economic evaluation tools, in addition to the planning and conduct of RCTs, may enhance clinical trial site performances. Considering the strengths and limitations of each study type, clinical researchers should explore the contextual worthiness of either design in promulgating knowledge. They should focus on quality of conduct and reporting that may allow for the liberation of limited public and private clinical research funding.

Crosslinked wholly aromatic polyether membranes based on quinoline derivatives and their application in high temperature polymer electrolyte membrane fuel cells

NASA Astrophysics Data System (ADS)

Kallitsis, K. J.; Nannou, R.; Andreopoulou, A. K.; Daletou, M. K.; Papaioannou, D.; Neophytides, S. G.; Kallitsis, J. K.

2018-03-01

An AB type difunctional quinoline based monomer bearing a pentafluorophenyl unit combined with a phenol functionality is being synthesized and homopolymerized to create linear aromatic polyethers as polymer electrolytes for HT-PEM FCs applications. Several conditions are tested for the optimized synthesis of the monomer and homopolymer. Additionally, covalent crosslinking through aromatic polyether bond formation enables the creation of wholly aromatic crosslinked polymeric electrolyte membranes. More specifically, the perfluorophenyl units are crosslinked with other hydroxyl end functionalized moieties, providing membranes with enhanced chemical and mechanical properties that are moreover easily doped with phosphoric acid even at ambient temperatures. All membranes are evaluated for their structural and thermal characteristics and their doping ability with phosphoric acid. Selected crosslinked membranes are further tested in terms of their single cell performance at the temperature range 160 °C-200 °C showing promising performance and high conductivity values even up to 0.2 S cm-1 in some cases.

Layered conductive polymer on nylon membrane templates for high performance, thin-film supercapacitor electrodes

NASA Astrophysics Data System (ADS)

Shi, HaoTian Harvey; Naguib, Hani E.

2016-04-01

Flexible Thin-film Electrochemical Capacitors (ECs) are emerging technology that plays an important role as energy supply for various electronics system for both present era and the future. Intrinsically conductive polymers (ICPs) are promising pseudo-capacitive materials as they feature both good electrical conductivity and high specific capacitance. This study focuses on the construction and characterization of ultra-high surface area porous electrodes based on coating of nano-sized conductive polymer materials on nylon membrane templates. Herein, a novel nano-engineered electrode material based on nylon membranes was presented, which allows the creation of super-capacitor devices that is capable of delivering competitive performance, while maintaining desirable mechanical characteristics. With the formation of a highly conductive network with the polyaniline nano-layer, the electrical conductivity was also increased dramatically to facilitate the charge transfer process. Cyclic voltammetry and specific capacitance results showed promising application of this type of composite materials for future smart textile applications.

An aspartate and a water molecule mediate efficient acid-base catalysis in a tailored antibody pocket.

PubMed

Debler, Erik W; Müller, Roger; Hilvert, Donald; Wilson, Ian A

2009-11-03

Design of catalysts featuring multiple functional groups is a desirable, yet formidable goal. Antibody 13G5, which accelerates the cleavage of unactivated benzisoxazoles, is one of few artificial enzymes that harness an acid and a base to achieve efficient proton transfer. X-ray structures of the Fab-hapten complexes of wild-type 13G5 and active-site variants now afford detailed insights into its mechanism. The parent antibody preorganizes Asp(H35) and Glu(L34) to abstract a proton from substrate and to orient a water molecule for leaving group stabilization, respectively. Remodeling the environment of the hydrogen bond donor with a compensatory network of ordered waters, as seen in the Glu(L34) to alanine mutant, leads to an impressive 10(9)-fold rate acceleration over the nonenzymatic reaction with acetate, illustrating the utility of buried water molecules in bifunctional catalysis. Generalization of these design principles may aid in creation of catalysts for other important chemical transformations.

Creationism as Science: What Every Teacher-Scientist Should Know.

ERIC Educational Resources Information Center

Gatzke, Ken W.

1985-01-01

Addresses philosophical problems of the evolution/creationism debate (including underlying assumptions of creationism and nature of science), suggesting that creationism cannot be presented as science in science courses because it fails to qualify as a science. Prediction and explanation, absolute creationism, and a fundamental difficulty in…

Remanufacturing Aided Added-Value Creation, Innovations Meeting to Deliver Sustainable Manufacturing

NASA Astrophysics Data System (ADS)

Tariq Abullah, Ziyad; Guo, Shun Sheng; Yun, Sheng Bu

2015-05-01

End-of-life scrap steel such as vehicles bulks and bodies, steel wheel and shells are easily land filled at the end-of-life when treated in a developing country with non-industrial infrastructure. Research idea is about composite shape steel remanufacturing to be sheet steel for construction application through nested recovered pieces of scrap steel within new sheet steel base to meet innovation value creation of remanufactured steel and innovation eco-design of steel products to close supply chain through linkage developed and developing countries of non-industrial infrastructure economy. That can be satisfied through comprehensive business- education-training model conduction firstly at the developing countries to reduce costs and change the intensive labour remanufacturing paradigm collaboratively. Sustainable remanufacturing business model can be applied based on infrastructure of educational institutions such as institutes of technology to adopt environmental, economic, and social developments as triple bottom line sustainability. Such innovation value creation is driven by eco-design and eco-innovation enabling where the meet to deliver human development, employment, and education conscious environment and bench mark recommendations of development directions for upgrading to apply business that allows eco-societies to emerge, through cooperative steel scrap processing.

Application of forwardchaining method to diagnosis of onion plant diseases

NASA Astrophysics Data System (ADS)

Sitanggang, Delima; Siregar, Saut D.; Situmeang, Suryani M. F.; Indra, Evta; Sagala, Ayu R.; Sihombing, Oloan; Nababan, Marlince; Pasaribu, Hendra; Damanik, Rudolf R.; Turnip, Mardi; Saragih, Rijois I. E.

2018-04-01

Red Onion is a tuber plant that is widely used by the people of Indonesia, both as herbs and herbal medicines. Onion farmers have limitations in identifying diseases that attack their crops.This disease can cause crop failure against the onion.This design begins with the creation of a knowledge base up to input-output design with forward chaining method. The results of this design can assist farmers in identifying their plant diseases. Based on diagnostic results of several methods that have been done testing can diagnose diseases contained in onion plants. With symptoms data that has been determined by the expert with the value of each symptom is different. As for the symptoms that have been determined that the leaves contain patches with a value of 0.3, White leaf spots value 0.4, Leaf spots form a purple zone if it is severe 0.5, Leaf tip of 0.2, Tubers rot 0.4. Based on the above diagnostic results then get the value of diagnosis 67% forward chaining with trotol disease type, Purple spotting.

Implementation of a frame-based representation in CLIPS

NASA Technical Reports Server (NTRS)

Assal, Hisham; Myers, Leonard

1990-01-01

Knowledge representation is one of the major concerns in expert systems. The representation of domain-specific knowledge should agree with the nature of the domain entities and their use in the real world. For example, architectural applications deal with objects and entities such as spaces, walls, and windows. A natural way of representing these architectural entities is provided by frames. This research explores the potential of using the expert system shell CLIPS, developed by NASA, to implement a frame-based representation that can accommodate architectural knowledge. These frames are similar but quite different from the 'template' construct in version 4.3 of CLIPS. Templates support only the grouping of related information and the assignment of default values to template fields. In addition to these features frames provide other capabilities including definition of classes, inheritance between classes and subclasses, relation of objects of different classes with 'has-a', association of methods (demons) of different types (standard and user-defined) to fields (slots), and creation of new fields at run-time. This frame-based representation is implemented completely in CLIPS. No change to the source code is necessary.

Isomorphic pressures, institutional strategies, and knowledge creation in the health care sector.

PubMed

Yang, Chen-Wei; Fang, Shih-Chieh; Huang, Wei-Min

2007-01-01

Health care organizations are facing surprisingly complex challenges, including new treatment and diagnostic technologies, ongoing pressures for health care institutional reform, the emergence of new organizational governance structures, and knowledge creation for the health care system. To maintain legitimacy in demanding environments, organizations tend to copy practices of similar organizations, which lead to isomorphism, and to use internal strategies to accommodate changes. A concern is that a poor fit between isomorphic pressures and internal strategies can interfere with developmental processes, such as knowledge creation. The purposes of this article are to, first, develop a set of propositions, based on institutional theory, as a theoretical framework that might explain the influence of isomorphic pressures on institutional processes through which knowledge is created within the health care sector and, second, propose that a good fit between isomorphic pressures factors and health care organizations' institutional strategic choices will enhance the health care organizations' ability to create knowledge. To develop a theoretical framework, we developed a set of propositions based on literature pertaining to the institutional theory perspective of isomorphic pressures and the response of health care organizations to isomorphic pressures. Institutional theory perspectives of isomorphic pressures and institutional strategies may provide a new understanding for health care organizations seeking effective knowledge creation strategies within institutional environment of health care sector. First, the ability to identify three forces for isomorphic change is critical for managers. Second, the importance of a contingency approach by health care managers can lead to strategies tailoring to cope with uncertainties facing their organizations.

Enhanced Management of and Access to Hurricane Sandy Ocean and Coastal Mapping Data

NASA Astrophysics Data System (ADS)

Eakins, B.; Neufeld, D.; Varner, J. D.; McLean, S. J.

2014-12-01

NOAA's National Geophysical Data Center (NGDC) has significantly improved the discovery and delivery of its geophysical data holdings, initially targeting ocean and coastal mapping (OCM) data in the U.S. coastal region impacted by Hurricane Sandy in 2012. We have developed a browser-based, interactive interface that permits users to refine their initial map-driven data-type choices prior to bulk download (e.g., by selecting individual surveys), including the ability to choose ancillary files, such as reports or derived products. Initial OCM data types now available in a U.S. East Coast map viewer, as well as underlying web services, include: NOS hydrographic soundings and multibeam sonar bathymetry. Future releases will include trackline geophysics, airborne topographic and bathymetric-topographic lidar, bottom sample descriptions, and digital elevation models.This effort also includes working collaboratively with other NOAA offices and partners to develop automated methods to receive and verify data, stage data for archive, and notify data providers when ingest and archive are completed. We have also developed improved metadata tools to parse XML and auto-populate OCM data catalogs, support the web-based creation and editing of ISO-compliant metadata records, and register metadata in appropriate data portals. This effort supports a variety of NOAA mission requirements, from safe navigation to coastal flood forecasting and habitat characterization.

Ideas for the rapid development of the structural models in mechanical engineering

NASA Astrophysics Data System (ADS)

Oanta, E.; Raicu, A.; Panait, C.

2017-08-01

Conceiving computer based instruments is a long run concern of the authors. Some of the original solutions are: optimal processing of the large matrices, interfaces between the programming languages, approximation theory using spline functions, numerical programming increased accuracy based on the extended arbitrary precision libraries. For the rapid development of the models we identified the following directions: atomization, ‘librarization’, parameterization, automatization and integration. Each of these directions has some particular aspects if we approach mechanical design problems or software development. Atomization means a thorough top-down decomposition analysis which offers an insight regarding the basic features of the phenomenon. Creation of libraries of reusable mechanical parts and libraries of programs (data types, functions) save time, cost and effort when a new model must be conceived. Parameterization leads to flexible definition of the mechanical parts, the values of the parameters being changed either using a dimensioning program or in accord to other parts belonging to the same assembly. The resulting templates may be also included in libraries. Original software applications are useful for the model’s input data generation, to input the data into CAD/FEA commercial applications and for the data integration of the various types of studies included in the same project.

Zometool Rationalization of Freeform Surfaces.

PubMed

Zimmer, Henrik; Kobbelt, Leif

2014-10-01

An ever broader availability of freeform designs together with an increasing demand for product customization has lead to a rising interest in efficient physical realization of such designs, the trend toward personal fabrication. Not only large-scale architectural applications are (becoming increasingly) popular but also different consumer-level rapid-prototyping applications, including toy and 3D puzzle creation. In this work we present a method for do-it-yourself reproduction of freeform designs without the typical limitation of state-of-the-art approaches requiring manufacturing custom parts using semi-professional laser cutters or 3D printers. Our idea is based on a popular mathematical modeling system (Zometool) commonly used for modeling higher dimensional polyhedra and symmetric structures such as molecules and crystal lattices. The proposed method extends the scope of Zometool modeling to freeform, disk-topology surfaces. While being an efficient construction system on the one hand (consisting only of a single node type and nine different edge types), this inherent discreteness of the Zometool system, on the other hand gives rise to a hard approximation problem. We base our method on a marching front approach, where elements are not added in a greedy sense, but rather whole regions on the front are filled optimally, using a set of problem specific heuristics to keep complexity under control.

Anatomy of deception: a behavioral contingency analysis.

PubMed

Mechner, Francis

2010-05-01

Deception, a basic and pervasive biological phenomenon, takes many forms, variously referred to as mimicry, trickery, seduction, pretense, feigning, masquerading, impersonation, distraction, or false promises, and these share certain common distinguishing behavioral elements that permit them to be classified into categories. A symbolic language for the codification and analysis of behavioral contingencies shows that all instances of deception are based on a misperception, misprediction, non-perception, or non-prediction by the deceived party, and can be further categorized based on features of the contingencies that define them. Instances of particular interest are those in which a deceiving party predicts (and in that sense "intends") the deception. In those instances, the effect of the deception is usually to the deceiving party's benefit and to the deceived party's detriment. In economics, finance, business, military operations, public affairs, education, and everyday social interaction, deception takes numerous forms. Special forms, usually involving obfuscation, concealment, counterfeiting, and misrepresentation, occur in certain prevalent types of property transfer, including securitization, the creation of derivatives, and various types of Ponzi schemes. Such property transfers tend to be driven by opportunities for deception. They all involve blurring and clouding of the contingencies that defined the transferred properties, thus permitting their obfuscation. Copyright (c) 2009 Elsevier B.V. All rights reserved.

Value Creation in the Knowledge-Based Economy

ERIC Educational Resources Information Center

Liu, Fang-Chun

2013-01-01

Effective investment strategies help companies form dynamic core organizational capabilities allowing them to adapt and survive in today's rapidly changing knowledge-based economy. This dissertation investigates three valuation issues that challenge managers with respect to developing business-critical investment strategies that can have…

Gradient-Hierarchic-Aligned Porosity SiOC Ceramics

PubMed Central

Vakifahmetoglu, Cekdar; Zeydanli, Damla; Innocentini, Murilo Daniel de Mello; Ribeiro, Fernanda dos Santos; Lasso, Paulo Renato Orlandi; Soraru, Gian Domenico

2017-01-01

This work describes a simple technique to produce porous ceramics with aligned porosity having very high permeability and specific surface area. SiOC-based compositions were processed from blends of three types of preceramic polymer and a catalyst, followed by curing and pyrolysis. The heating applied from the bottom of molds promoted the nucleation, expansion and rising of gas bubbles, and the creation of a ceramic matrix with axially oriented channels interconnected by small round pores. The samples were analyzed by SEM, tomography, BET, water immersion porosimetry and permeation to gas flow. The resulting bodies presented levels of open porosity (69.9–83.4%), average channel diameter (0.59–1.25 mm) and permeability (0.56–3.83 × 10−9 m2) comparable to those of ceramic foams and honeycomb monoliths, but with specific surface area (4.8–121.9 m2/g) typical adsorbents, enabling these lotus-type ceramics to be advantageously used as catalytic supports and adsorption components in several environmental control applications. PMID:28106140

Mathematical Metaphors: Problem Reformulation and Analysis Strategies

NASA Technical Reports Server (NTRS)

Thompson, David E.

2005-01-01

This paper addresses the critical need for the development of intelligent or assisting software tools for the scientist who is working in the initial problem formulation and mathematical model representation stage of research. In particular, examples of that representation in fluid dynamics and instability theory are discussed. The creation of a mathematical model that is ready for application of certain solution strategies requires extensive symbolic manipulation of the original mathematical model. These manipulations can be as simple as term reordering or as complicated as discovery of various symmetry groups embodied in the equations, whereby Backlund-type transformations create new determining equations and integrability conditions or create differential Grobner bases that are then solved in place of the original nonlinear PDEs. Several examples are presented of the kinds of problem formulations and transforms that can be frequently encountered in model representation for fluids problems. The capability of intelligently automating these types of transforms, available prior to actual mathematical solution, is advocated. Physical meaning and assumption-understanding can then be propagated through the mathematical transformations, allowing for explicit strategy development.

De Novo Design of Protein Mimics of B-DNA

PubMed Central

Yüksel, Deniz; Bianco, Piero R.; Kumar, Krishna

2015-01-01

Structural mimicry of DNA is utilized in nature as a strategy to evade molecular defences mounted by host organisms. One such example is the protein Ocr – the first translation product to be expressed as the bacteriophage T7 infects E. coli. The structure of Ocr reveals an intricate and deliberate arrangement of negative charges that endows it with the ability to mimic ∼24 base pair stretches of B–DNA. This uncanny resemblance to DNA enables Ocr to compete in binding the type I restriction modification (R/M) system, and neutralizes the threat of hydrolytic cleavage of viral genomic material. Here, we report the de novo design and biophysical characterization of DNA mimicking peptides, and describe the inhibitory action of the designed helical bundles on a type I R/M enzyme, EcoR124I. This work validates the use of charge patterning as a design principle for creation of protein mimics of DNA, and serves as a starting point for development of therapeutic peptide inhibitors against human pathogens that employ molecular camouflage as part of their invasion stratagem. PMID:26568416

Ricor's Nanostar water vapor compact cryopump: applications and model overview

NASA Astrophysics Data System (ADS)

Harris, Rodney S.; Nachman, Ilan; Tauber, Tomer; Kootzenko, Michael; Barak, Boris; Aminov, Eli; Gover, Dan

2017-05-01

Ricor Systems has developed a compact, single stage cryopump that fills the gap where GM and other type cryopumps can't fit in. Stirling cycle technology is highly efficient and is the primary cryogenic technology for use in IR, SWIR, HOT FPA, and other IR detector technology in military, security, and aerospace applications. Current GM based dual stage cryopumps have been the legacy type water vapor pumping system for more than 50 years. However, the typically large cryopanel head, compressor footprint, and power requirements make them not cost and use effective for small, tabletop evaporation / sputtering systems, portable analysis systems, and other systems requiring small volume vacuum creation from medium, high, and UHV levels. This single stage cryopump works well in-line with diffusion and molecular turbopumps. Studies have shown effective cooperation with non-evaporable getter technology as well for UHV levels. Further testing in this area are ongoing. Temperatures created by Stirling cycle cryogenic coolers develop a useful temperature range of 40 to 150K. Temperatures of approximately 100 K are sufficient to condense water and all hydrocarbons oil vapors.

Characterization of Listeria monocytogenes from an ice cream plant by serotyping and pulsed-field gel electrophoresis.

PubMed

Miettinen, M K; Björkroth, K J; Korkeala, H J

1999-02-18

One dominating strain of serotype 1/2b was found when serotyping and pulsed-field gel electrophoresis (PFGE) patterns were used for the characterization of 41 Listeria monocytogenes isolates originating from an ice cream plant. Samples were taken from the production environment, equipment and ice cream during the years 1990-1997. Serotyping divided the isolates into two serovars, 1/2b and 4b. Three rare-cutting enzymes (ApaI, AscI and SmaI) were used in the creation of PFGE patterns. AscI resulted in the best restriction enzyme digestion patterns (REDPs) for visual comparison. Eight different AscI REDPs were obtained, whereas ApaI produced six and SmaI seven banding patterns. When one-band differences are taken into account, 12 different PFGE types were distinguished based on information obtained with all three enzymes. The dominant PFGE type was found to have persisted in the ice cream plant for seven years. Improved and precisely targeted cleaning and disinfection practices combined with structural changes making for easier cleaning of the packaging machine, resulted in eradication of L. monocytogenes from this plant.

Coherence of beam arrays propagating in the turbulent atmosphere

NASA Astrophysics Data System (ADS)

Charnotskii, Mikhail

2010-04-01

We analyze some recent publications addressing propagation of the partially coherent polarized beams and beam arrays in the turbulent atmosphere. We show that the published results are limited to the scalar propagation model, and are not particular to the beam polarization. Therefore these results are equally relevant for the scalar beam pairs and arrays discriminated by some parameters such as small frequency shift, time delay or geometry, but not necessary the polarization. We use the virtual incoherent source model to derive the general form of the mutual coherence function of the two Schell-type beams. We discuss some physical stochastic models that result in the creation of the Schell-type beams and beam arrays. New classes of the uniformly, nonuniformly and nonlocally coherent beam pairs emerge naturally from this analysis. Rigorous, Markov approximation-based, propagation model provides relatively simple analytic results for the second-order moments of the optical field of the partially-coherent individual beams and beam pairs. We examine the changes of the beam mutual coherence in the process of the free-space propagation and propagation through the turbulent atmosphere.

The Atlas of Physiology and Pathophysiology: Web-based multimedia enabled interactive simulations.

PubMed

Kofranek, Jiri; Matousek, Stanislav; Rusz, Jan; Stodulka, Petr; Privitzer, Pavol; Matejak, Marek; Tribula, Martin

2011-11-01

The paper is a presentation of the current state of development for the Atlas of Physiology and Pathophysiology (Atlas). Our main aim is to provide a novel interactive multimedia application that can be used for biomedical education where (a) simulations are combined with tutorials and (b) the presentation layer is simplified while the underlying complexity of the model is retained. The development of the Atlas required the cooperation of many professionals including teachers, system analysts, artists, and programmers. During the design of the Atlas, tools were developed that allow for component-based creation of simulation models, creation of interactive multimedia and their final coordination into a compact unit based on the given design. The Atlas is a freely available online application, which can help to explain the function of individual physiological systems and the causes and symptoms of their disorders. Copyright © 2010 Elsevier Ireland Ltd. All rights reserved.

The TextBase project--implementation of a base level message supporting electronic patient record transfer in English general practice.

PubMed

Booth, N; Jain, N L; Sugden, B

1999-01-01

The TextBase project is a laboratory experiment to assess the feasibility of a common exchange format for sending a transcription of the contents of the Electronic Patient Record (EPR) between different general practices, when patients move from one practice to another in the NHS in England. The project was managed using a partnership arrangement between the four EPR systems vendors who agreed to collaborate and the project team. It lasted one year and consisted of an iterative design process followed by creation of message generation and reading modules within the collaborating EPR systems according to a software requirement specification created by the project team. The paper describes the creation of a common record display format, the implementation of transfer using a floppy disk in the lab, and considers the further barriers before a national implementation might be achieved.

Applying the miniaturization technologies for biosensor design.

PubMed

Derkus, Burak

2016-05-15

Microengineering technologies give us some opportunities in developing high-tech sensing systems that operate with low volumes of samples, integrates one or more laboratory functions on a single substrate, and enables automation. These millimetric sized devices can be produced for only a few dollars, which makes them promising candidates for mass-production. Besides electron beam lithography, stencil lithography, nano-imprint lithography or dip pen lithography, basic photolithography is the technique which is extensively used for the design of microengineered sensing systems. This technique has some advantages such as easy-to-manufacture, do not require expensive instrumentation, and allow creation of lower micron-sized patterns. In this review, it has been focused on three different type of microengineered sensing devices which are developed using micro/nano-patterning techniques, microfluidic technology, and microelectromechanics system based technology. Copyright © 2016 Elsevier B.V. All rights reserved.

Micro-UAV tracking framework for EO exploitation

NASA Astrophysics Data System (ADS)

Browning, David; Wilhelm, Joe; Van Hook, Richard; Gallagher, John

2012-06-01

Historically, the Air Force's research into aerial platforms for sensing systems has focused on low-, mid-, and highaltitude platforms. Though these systems are likely to comprise the majority of the Air Force's assets for the foreseeable future, they have limitations. Specifically, these platforms, their sensor packages, and their data exploitation software are unsuited for close-quarter surveillance, such as in alleys and inside of buildings. Micro-UAVs have been gaining in popularity, especially non-fixed-wing platforms such as quad-rotors. These platforms are much more appropriate for confined spaces. However, the types of video exploitation techniques that can effectively be used are different from the typical nadir-looking aerial platform. This paper discusses the creation of a framework for testing existing and new video exploitation algorithms, as well as describes a sample micro-UAV-based tracker.

Component Technology for High-Performance Scientific Simulation Software

DOE Office of Scientific and Technical Information (OSTI.GOV)

Epperly, T; Kohn, S; Kumfert, G

2000-11-09

We are developing scientific software component technology to manage the complexity of modem, parallel simulation software and increase the interoperability and re-use of scientific software packages. In this paper, we describe a language interoperability tool named Babel that enables the creation and distribution of language-independent software libraries using interface definition language (IDL) techniques. We have created a scientific IDL that focuses on the unique interface description needs of scientific codes, such as complex numbers, dense multidimensional arrays, complicated data types, and parallelism. Preliminary results indicate that in addition to language interoperability, this approach provides useful tools for thinking about themore » design of modem object-oriented scientific software libraries. Finally, we also describe a web-based component repository called Alexandria that facilitates the distribution, documentation, and re-use of scientific components and libraries.« less

Creation of Exercises for Team-Based Learning in Business

ERIC Educational Resources Information Center

Timmerman, John E.; Morris, R. Franklin, Jr.

2015-01-01

Team-based learning (TBL) is an approach that builds on both the case method and problem-based learning and has been widely adopted in the sciences and healthcare disciplines. In recent years business disciplines have also discovered the value of this approach. One of the key characteristics of the team-based learning approach consists of…

Evidence-Based Administration for Decision Making in the Framework of Knowledge Strategic Management

ERIC Educational Resources Information Center

Del Junco, Julio Garcia; Zaballa, Rafael De Reyna; de Perea, Juan Garcia Alvarez

2010-01-01

Purpose: This paper seeks to present a model based on evidence-based administration (EBA), which aims to facilitate the creation, transformation and diffusion of knowledge in learning organizations. Design/methodology/approach: A theoretical framework is proposed based on EBA and the case method. Accordingly, an empirical study was carried out in…

[Immunosensors: sources of origin, achievements and perspectives].

PubMed

Starodub, M F; Starodub, V M

2000-01-01

The analysis of the recent data in the literature and results of investigations in the field of the development and study of function efficiency of different types of immune sensors, that are performed at the Department of Biochemistry Sensory and Regulatory Systems of the A. V. Palladin Institute of Biochemistry of Ukrainian National Academy of Sciences are presented. Sources of origination and perspectives of the devlopment of biosensors are discussed as well. The paper also gives an overview of main research projects at the Department, mainly in the filed of biosensors. They include development of the scientific bases for the creation of a new generation of chemo- and biosensors for their application in medicine and ecology. Multi-immune, multi-enzyme and combined multi-parametrical sensors can provide express analyses in laboratory and field conditions with the purpose to perform immune chemical diagnostics of diabet, kidney diseases, immune defficiencies, autoimmune, allergic, pre-infarction and pre-tumor states as well as to control total toxicity of the environment and identification of main types of toxic elements in it. The investigations are based on the latest achivements in the field of physics, chemistry, information technology and electronics with the use of different types of planar electrodes, ion sensitive field effect transistors (ISFETs), semiconductor capacitive structures, termistors, optrodes, piezocrystalls and application of such methods and effects as laser correlation spectroscopy, chemiluminescence, fluorescence, surface plasmon resonance, photoluminescence of porous silicon, interferometry, evanescent wave technique, nonemmiting energy transfer and holography.

The National Children's Study: Recruitment Outcomes Using an Enhanced Household-Based Approach.

PubMed

Blaisdell, Laura L; Zellner, Jennifer A; King, Alison A; Faustman, Elaine; Wilhelm, Mari; Hudak, Mark L; Annett, Robert D

2016-06-01

Ten National Children's Study (NCS) study locations with diverse demographic characteristics used an enhanced household-based recruitment (EHBR) approach to enroll preconceptional and pregnant women. Study centers used different types and dosages of community outreach and engagement (COE) activities and supplemental strategies. The goal of the study was to determine whether variability in enumeration and recruitment outcomes correlated with study location characteristics or types and dosages of COE activities (number of COE events, number of advance household mailings, total media expenditures, and total COE expenditures). Each of the sites provided data on COE activities, protocol implementation, supplemental recruitment activities, location demographic characteristics, and enumeration/recruitment outcomes. COE activities varied across sites in breadth and scope. Numerous strategies were used, including media advertising, social media, participation in community-wide events, presentations to stakeholders, and creation of advisory boards. Some sites included supplemental recruitment efforts. EHBR sites enrolled 1404 women at the initial pregnancy screening. No significant relationships were found between study location demographic characteristics or between the types and dosages of COE activities and recruitment outcomes. Probability sampling for a long-term study requires a positive image with stakeholders and within communities; this requirement may be especially true for door-to-door recruitment. EHBR sites successfully recruited a representative sample of preconceptional and pregnant women. Sites reported implementing similar COE activities but with varying dosage and cost; however, analyses did not support a benefit of COE strategies on study recruitment. Copyright © 2016 by the American Academy of Pediatrics.

Solar test of Dirac's large number hypothesis. [multiplicative creation model for solar evolution

NASA Technical Reports Server (NTRS)

Chin, C.-W.; Stothers, R.

1975-01-01

An investigation is conducted regarding the implications of Dirac's theories (1973, 1974) concerning the creation of new matter. It is found that Dirac's theory of multiplicative creation, but not his theory of additive creation, is not in contradiction with known facts about the sun. According to the theory of additive creation, matter is formed uniformly throughout space. The concept of multiplicative creation implies that existing matter multiplies itself in proportion to the amount of matter already present.

Ada Compiler Validation Summary Report: Certificate Number: 940630W1. 11360, Radional Software Corporation, VADSself for DEC Alpha AXP OSF/1, Product Number: 2100-01439, Version 6.2, DEC 3000 Model 500 AXP under OSF/1, V1.3

DTIC Science & Technology

1994-07-21

for the task’s type. The address of an ADA KRN DEFS.TASK ATTR T record is the argument of the piagma and- is passed to the underlying microkernel at...task creation. The task attributes are microkernel dependent. See ada krn defs.a in standard for the type definition of TASK ATTR T and the different...ENDIAN, BIG _4DIAN BYTE-ORDER: constant BYTE ORDER T :- LITTLEENDIAN; type L4 _ADDRESS is private; NO_ LONG_ADDR : constant 10CG_ADDRESS; function

Unidata's Vision for Transforming Geoscience by Moving Data Services and Software to the Cloud

NASA Astrophysics Data System (ADS)

Ramamurthy, M. K.; Fisher, W.; Yoksas, T.

2014-12-01

Universities are facing many challenges: shrinking budgets, rapidly evolving information technologies, exploding data volumes, multidisciplinary science requirements, and high student expectations. These changes are upending traditional approaches to accessing and using data and software. It is clear that Unidata's products and services must evolve to support new approaches to research and education. After years of hype and ambiguity, cloud computing is maturing in usability in many areas of science and education, bringing the benefits of virtualized and elastic remote services to infrastructure, software, computation, and data. Cloud environments reduce the amount of time and money spent to procure, install, and maintain new hardware and software, and reduce costs through resource pooling and shared infrastructure. Cloud services aimed at providing any resource, at any time, from any place, using any device are increasingly being embraced by all types of organizations. Given this trend and the enormous potential of cloud-based services, Unidata is taking moving to augment its products, services, data delivery mechanisms and applications to align with the cloud-computing paradigm. Specifically, Unidata is working toward establishing a community-based development environment that supports the creation and use of software services to build end-to-end data workflows. The design encourages the creation of services that can be broken into small, independent chunks that provide simple capabilities. Chunks could be used individually to perform a task, or chained into simple or elaborate workflows. The services will also be portable, allowing their use in researchers' own cloud-based computing environments. In this talk, we present a vision for Unidata's future in a cloud-enabled data services and discuss our initial efforts to deploy a subset of Unidata data services and tools in the Amazon EC2 and Microsoft Azure cloud environments, including the transfer of real-time meteorological data into its cloud instances, product generation using those data, and the deployment of TDS, McIDAS ADDE and AWIPS II data servers and the Integrated Data Server visualization tool.

Making It Personal: The Importance of Student Experience in Creating Autonomy-Supportive Classrooms for Millennial Learners

ERIC Educational Resources Information Center

Conklin, Thomas A.

2013-01-01

This article reviews andragogy as the philosophy resident in the broad arena of experience-based learning. Beneath the umbrella of experience-based learning lie the specific classroom orientations of student-centered learning, problem-based learning, and classrooms as organizations. These orientations contribute to the creation of…

Is Teacher Assessment Reliable or Valid for High School Students under a Web-Based Portfolio Environment?

ERIC Educational Resources Information Center

Chang, Chi-Cheng; Wu, Bing-Hong

2012-01-01

This study explored the reliability and validity of teacher assessment under a Web-based portfolio assessment environment (or Web-based teacher portfolio assessment). Participants were 72 eleventh graders taking the "Computer Application" course. The students perform portfolio creation, inspection, self- and peer-assessment using the Web-based…

Ethical and technical considerations for the creation of cell lines in the head & neck and tissue harvesting for research and drug development (Part I): Techniques of tissue harvesting and propagation

PubMed Central

Upile, Tahwinder; Jerjes, Waseem; Kafas, Panagiotis; Singh, Sandeep U; Sudhoff, Holger; Mahil, Jaspal; Sandison, Ann; Hopper, Colin

2009-01-01

Background Although much has been published for the development of cell lines, these were lab based and developed for scientific technical staff. Objective of review We present a simple and successful protocol for the development of cell lines and tissue harvesting for the clinical scientist. We also discuss the ethical implications of tissue retention and present a generic consent form. Conclusion The advantages of hospital-based cell line creation are numerous. We can be more certain that cell lines are developed from the particular tissues of interest and accurate anatomical and appropriate clinico-pathological control tissues are also harvested. We can also be certain of less cell line cross contamination. PMID:19344501

Implementation of megaprojects for the creation of tourist clusters in Russia based on the concept of energy efficiency and sustainable construction

NASA Astrophysics Data System (ADS)

Orlov, Alexandr K.

2017-10-01

The article deals with the application of sustainable construction concept within implementation of megaprojects of tourist clusters development using energy saving technologies. The concept of sustainable construction includes the elements of green construction, energy management as well as aspects of the economic efficiency of construction projects implementation. The methodical approach to the implementation of megaprojects for the creation of tourist clusters in Russia based on the concept of energy efficiency and sustainable construction is proved. The conceptual approach to the evaluation of the ecological, social and economic components of the integral indicator of the effectiveness of the megaproject for the development of the tourist cluster is provided. The algorithm for estimation of the efficiency of innovative solutions in green construction is considered.

Educational-research laboratory "electric circuits" on the base of digital technologies

NASA Astrophysics Data System (ADS)

Koroteyev, V. I.; Florentsev, V. V.; Florentseva, N. I.

2017-01-01

The problem of research activity of trainees' activation in the educational-research laboratory "Electric Circuits" using innovative methodological solutions and digital technologies is considered. The main task is in creation of the unified experimental research information-educational environment "Electrical Engineering". The problems arising during the developing and application of the modern software and hardware, experimental and research stands and digital control and measuring systems are presented. This paper presents the main stages of development and creation of educational-research laboratory "Electrical Circuits" at the Department of Electrical Engineering of NRNU MEPhI. The authors also consider the analogues of the described research complex offered by various educational institutions and companies. The analysis of their strengths and weaknesses, on which the advantages of the proposed solution are based, is held.

Exploiting Information Diffusion Feature for Link Prediction in Sina Weibo

NASA Astrophysics Data System (ADS)

Li, Dong; Zhang, Yongchao; Xu, Zhiming; Chu, Dianhui; Li, Sheng

2016-01-01

The rapid development of online social networks (e.g., Twitter and Facebook) has promoted research related to social networks in which link prediction is a key problem. Although numerous attempts have been made for link prediction based on network structure, node attribute and so on, few of the current studies have considered the impact of information diffusion on link creation and prediction. This paper mainly addresses Sina Weibo, which is the largest microblog platform with Chinese characteristics, and proposes the hypothesis that information diffusion influences link creation and verifies the hypothesis based on real data analysis. We also detect an important feature from the information diffusion process, which is used to promote link prediction performance. Finally, the experimental results on Sina Weibo dataset have demonstrated the effectiveness of our methods.

Exploiting Information Diffusion Feature for Link Prediction in Sina Weibo.

PubMed

Li, Dong; Zhang, Yongchao; Xu, Zhiming; Chu, Dianhui; Li, Sheng

2016-01-28

The rapid development of online social networks (e.g., Twitter and Facebook) has promoted research related to social networks in which link prediction is a key problem. Although numerous attempts have been made for link prediction based on network structure, node attribute and so on, few of the current studies have considered the impact of information diffusion on link creation and prediction. This paper mainly addresses Sina Weibo, which is the largest microblog platform with Chinese characteristics, and proposes the hypothesis that information diffusion influences link creation and verifies the hypothesis based on real data analysis. We also detect an important feature from the information diffusion process, which is used to promote link prediction performance. Finally, the experimental results on Sina Weibo dataset have demonstrated the effectiveness of our methods.

Method of recommending items to a user based on user interest

DOEpatents

Bollen, John; Van De Sompel, Herbert

2013-11-05

Although recording of usage data is common in scholarly information services, its exploitation for the creation of value-added services remains limited due to concerns regarding, among others, user privacy, data validity, and the lack of accepted standards for the representation, sharing and aggregation of usage data. A technical, standards-based architecture for sharing usage information is presented. In this architecture, OpenURL-compliant linking servers aggregate usage information of a specific user community as it navigates the distributed information environment that it has access to. This usage information is made OAI-PMH harvestable so that usage information exposed by many linking servers can be aggregated to facilitate the creation of value-added services with a reach beyond that of a single community or a single information service.

Usage based indicators to assess the impact of scholarly works: architecture and method

DOEpatents

Bollen, Johan [Santa Fe, NM; Van De Sompel, Herbert [Santa Fe, NM

2012-03-13

Although recording of usage data is common in scholarly information services, its exploitation for the creation of value-added services remains limited due to concerns regarding, among others, user privacy, data validity, and the lack of accepted standards for the representation, sharing and aggregation of usage data. A technical, standards-based architecture for sharing usage information is presented. In this architecture, OpenURL-compliant linking servers aggregate usage information of a specific user community as it navigates the distributed information environment that it has access to. This usage information is made OAI-PMH harvestable so that usage information exposed by many linking servers can be aggregated to facilitate the creation of value-added services with a reach beyond that of a single community or a single information service.

Bones of the Earth

ERIC Educational Resources Information Center

Correa, Jose Miguel

2014-01-01

The film "Bones of the Earth" (Riglin, Cunninham & Correa, 2014) is an experience in collective inquiry and visual creation based on arts-based research. Starting from the meeting of different subjectivities and through dialogue, planning, shooting and editing, an audiovisual text that reconstructs a reflexive process of collective…

Providing Alternatives to Nursing Home Care: An Interorganizational Analysis.

ERIC Educational Resources Information Center

Austin, Carol D.

The development of alternatives to institutionally based long-term care requires the creation of greater interdependence among community based agencies and the provision of appropriate interdependence as the foundation for coordinated service delivery. Theoretical models of interorganizational interdependence are examined and assessed for their…

Knowledge-Driven Event Extraction in Russian: Corpus-Based Linguistic Resources

PubMed Central

Solovyev, Valery; Ivanov, Vladimir

2016-01-01

Automatic event extraction form text is an important step in knowledge acquisition and knowledge base population. Manual work in development of extraction system is indispensable either in corpus annotation or in vocabularies and pattern creation for a knowledge-based system. Recent works have been focused on adaptation of existing system (for extraction from English texts) to new domains. Event extraction in other languages was not studied due to the lack of resources and algorithms necessary for natural language processing. In this paper we define a set of linguistic resources that are necessary in development of a knowledge-based event extraction system in Russian: a vocabulary of subordination models, a vocabulary of event triggers, and a vocabulary of Frame Elements that are basic building blocks for semantic patterns. We propose a set of methods for creation of such vocabularies in Russian and other languages using Google Books NGram Corpus. The methods are evaluated in development of event extraction system for Russian. PMID:26955386

Concept maps: A tool for knowledge management and synthesis in web-based conversational learning.

PubMed

Joshi, Ankur; Singh, Satendra; Jaswal, Shivani; Badyal, Dinesh Kumar; Singh, Tejinder

2016-01-01

Web-based conversational learning provides an opportunity for shared knowledge base creation through collaboration and collective wisdom extraction. Usually, the amount of generated information in such forums is very huge, multidimensional (in alignment with the desirable preconditions for constructivist knowledge creation), and sometimes, the nature of expected new information may not be anticipated in advance. Thus, concept maps (crafted from constructed data) as "process summary" tools may be a solution to improve critical thinking and learning by making connections between the facts or knowledge shared by the participants during online discussion This exploratory paper begins with the description of this innovation tried on a web-based interacting platform (email list management software), FAIMER-Listserv, and generated qualitative evidence through peer-feedback. This process description is further supported by a theoretical construct which shows how social constructivism (inclusive of autonomy and complexity) affects the conversational learning. The paper rationalizes the use of concept map as mid-summary tool for extracting information and further sense making out of this apparent intricacy.

Final Report for The Creation of a Physics-based Ground-effect Model, Phase 2 - Inclusion of the Effects of Wind, Stratification, and Shear into the New Ground Effect Model

NASA Technical Reports Server (NTRS)

Sarpkaya, Turgut

2006-01-01

The reduction of the separation of the leading and following aircrafts is desirable to enhance the airport capacity provided that there is a physics-based operational model applicable to all regions of the flight domain (out of ground effect, OGE; near ground effect, NGE; and in ground effect, IGE) and that the quality of the quantitative input from the measurements of the prevailing atmospheric conditions and the quality of the total airport operations regarding the safety and the sound interpretation of the prevailing conditions match the quality of the analysis and numerical simulations. In the absence of an analytical solution, the physics of the flow is best expressed by a mathematical model based on numerical simulations, field and laboratory experiments, and heuristic reasoning. This report deals with the creation of a sound physics-based real-time IGE model of the aircraft wake vortices subjected to crosswind, stratification and shear.

Building a Knowledge to Action Program in Stroke Rehabilitation.

PubMed

Janzen, Shannon; McIntyre, Amanda; Richardson, Marina; Britt, Eileen; Teasell, Robert

2016-09-01

The knowledge to action (KTA) process proposed by Graham et al (2006) is a framework to facilitate the development and application of research evidence into clinical practice. The KTA process consists of the knowledge creation cycle and the action cycle. The Evidence Based Review of Stroke Rehabilitation is a foundational part of the knowledge creation cycle and has helped guide the development of best practice recommendations in stroke. The Rehabilitation Knowledge to Action Project is an audit-feedback process for the clinical implementation of best practice guidelines, which follows the action cycle. The objective of this review was to: (1) contextualize the Evidence Based Review of Stroke Rehabilitation and Rehabilitation Knowledge to Action Project within the KTA model and (2) show how this process led to improved evidence-based practice in stroke rehabilitation. Through this process, a single centre was able to change clinical practice and promote a culture that supports the use of evidence-based practices in stroke rehabilitation.

Bird-community responses to habitat creation in a long-term, large-scale natural experiment.

PubMed

Whytock, Robin C; Fuentes-Montemayor, Elisa; Watts, Kevin; Barbosa De Andrade, Patanjaly; Whytock, Rory T; French, Paul; Macgregor, Nicholas A; Park, Kirsty J

2018-04-01

Ecosystem function and resilience are compromised when habitats become fragmented due to land-use change. This has led to national and international conservation strategies aimed at restoring habitat extent and improving functional connectivity (i.e., maintaining dispersal processes). However, biodiversity responses to landscape-scale habitat creation and the relative importance of spatial and temporal scales are poorly understood, and there is disagreement over which conservation strategies should be prioritized. We used 160 years of historic post-agricultural woodland creation as a natural experiment to evaluate biodiversity responses to habitat creation in a landscape context. Birds were surveyed in 101 secondary, broadleaf woodlands aged 10-160 years with ≥80% canopy cover and in landscapes with 0-17% broadleaf woodland cover within 3000 m. We used piecewise structural equation modeling to examine the direct and indirect relationships between bird abundance and diversity, ecological continuity, patch characteristics, and landscape structure and quantified the relative conservation value of local and landscape scales for bird communities. Ecological continuity indirectly affected overall bird abundance and species richness through its effects on stand structure, but had a weaker influence (effect size near 0) on the abundance and diversity of species most closely associated with woodland habitats. This was probably because woodlands were rapidly colonized by woodland generalists in ≤10 years (minimum patch age) but were on average too young (median 50 years) to be colonized by woodland specialists. Local patch characteristics were relatively more important than landscape characteristics for bird communities. Based on our results, biodiversity responses to habitat creation depended on local- and landscape-scale factors that interacted across time and space. We suggest that there is a need for further studies that focus on habitat creation in a landscape context and that knowledge gained from studies of habitat fragmentation and loss should be used to inform habitat creation with caution because the outcomes are not necessarily reciprocal. © 2017 The Authors. Conservation Biology published by Wiley Periodicals, Inc. on behalf of Society for Conservation Biology.

Fuzzy Euclidean wormholes in de Sitter space

NASA Astrophysics Data System (ADS)

Chen, Pisin; Hu, Yao-Chieh; Yeom, Dong-han

2017-07-01

We investigate Euclidean wormholes in Einstein gravity with a massless scalar field in de Sitter space. Euclidean wormholes are possible due to the analytic continuation of the time as well as complexification of fields, where we need to impose the classicality after the Wick-rotation to the Lorentzian signatures. For some parameters, wormholes are preferred than Hawking-Moss instantons, and hence wormholes can be more fundamental than Hawking-Moss type instantons. Euclidean wormholes can be interpreted in three ways: (1) classical big bounce, (2) either tunneling from a small to a large universe or a creation of a collapsing and an expanding universe from nothing, and (3) either a transition from a contracting to a bouncing phase or a creation of two expanding universes from nothing. These various interpretations shed some light on challenges of singularities. In addition, these will help to understand tensions between various kinds of quantum gravity theories.

Fuzzy Euclidean wormholes in de Sitter space

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chen, Pisin; Hu, Yao-Chieh; Yeom, Dong-han, E-mail: pisinchen@phys.ntu.edu.tw, E-mail: r04244003@ntu.edu.tw, E-mail: innocent.yeom@gmail.com

We investigate Euclidean wormholes in Einstein gravity with a massless scalar field in de Sitter space. Euclidean wormholes are possible due to the analytic continuation of the time as well as complexification of fields, where we need to impose the classicality after the Wick-rotation to the Lorentzian signatures. For some parameters, wormholes are preferred than Hawking-Moss instantons, and hence wormholes can be more fundamental than Hawking-Moss type instantons. Euclidean wormholes can be interpreted in three ways: (1) classical big bounce, (2) either tunneling from a small to a large universe or a creation of a collapsing and an expanding universemore » from nothing, and (3) either a transition from a contracting to a bouncing phase or a creation of two expanding universes from nothing. These various interpretations shed some light on challenges of singularities. In addition, these will help to understand tensions between various kinds of quantum gravity theories.« less

Fuzzy Euclidean wormholes in de Sitter space

DOE PAGES

Chen, Pisin; Hu, Yao-Chieh; Yeom, Dong-han

2017-07-03

Here, we investigate Euclidean wormholes in Einstein gravity with a massless scalar field in de Sitter space. Euclidean wormholes are possible due to the analytic continuation of the time as well as complexification of fields, where we need to impose the classicality after the Wick-rotation to the Lorentzian signatures. Furthermore, we prefer wormholes for some parameters, rather than Hawking-Moss instantons, and hence wormholes can be more fundamental than Hawking-Moss type instantons. Euclidean wormholes can be interpreted in three ways: (1) classical big bounce, (2) either tunneling from a small to a large universe or a creation of a collapsing andmore » an expanding universe from nothing, and (3) either a transition from a contracting to a bouncing phase or a creation of two expanding universes from nothing. These various interpretations shed some light on challenges of singularities. In addition, these will help to understand tensions between various kinds of quantum gravity theories.« less

Ethical aspects of creating human-nonhuman chimeras capable of human gamete production and human pregnancy.

PubMed

Palacios-González, César

2015-01-01

In this paper I explore some of the moral issues that could emerge from the creation of human-nonhuman chimeras (HNH-chimeras) capable of human gamete production and human pregnancy. First I explore whether there is a cogent argument against the creation of HNH-chimeras that could produce human gametes. I conclude that so far there is none, and that in fact there is at least one good moral reason for producing such types of creatures. Afterwards I explore some of the moral problems that could emerge from the fact that a HNH-chimera could become pregnant with a human conceptus. I focus on two sets of problems: problems that would arise by virtue of the fact that a human is gestated by a nonhuman creature, and problems that would emerge from the fact that such pregnancies could affect the health of the HNH-chimera.

Achieving behavioral control with millisecond resolution in a high-level programming environment

PubMed Central

Asaad, Wael F.; Eskandar, Emad N.

2008-01-01

The creation of psychophysical tasks for the behavioral neurosciences has generally relied upon low-level software running on a limited range of hardware. Despite the availability of software that allows the coding of behavioral tasks in high-level programming environments, many researchers are still reluctant to trust the temporal accuracy and resolution of programs running in such environments, especially when they run atop non-real-time operating systems. Thus, the creation of behavioral paradigms has been slowed by the intricacy of the coding required and their dissemination across labs has been hampered by the various types of hardware needed. However, we demonstrate here that, when proper measures are taken to handle the various sources of temporal error, accuracy can be achieved at the one millisecond time-scale that is relevant for the alignment of behavioral and neural events. PMID:18606188

Demonstration of the spin solar cell and spin photodiode effect

PubMed Central

Endres, B.; Ciorga, M.; Schmid, M.; Utz, M.; Bougeard, D.; Weiss, D.; Bayreuther, G.; Back, C.H.

2013-01-01

Spin injection and extraction are at the core of semiconductor spintronics. Electrical injection is one method of choice for the creation of a sizeable spin polarization in a semiconductor, requiring especially tailored tunnel or Schottky barriers. Alternatively, optical orientation can be used to generate spins in semiconductors with significant spin-orbit interaction, if optical selection rules are obeyed, typically by using circularly polarized light at a well-defined wavelength. Here we introduce a novel concept for spin injection/extraction that combines the principle of a solar cell with the creation of spin accumulation. We demonstrate that efficient optical spin injection can be achieved with unpolarized light by illuminating a p-n junction where the p-type region consists of a ferromagnet. The discovered mechanism opens the window for the optical generation of a sizeable spin accumulation also in semiconductors without direct band gap such as Si or Ge. PMID:23820766

Fuzzy Euclidean wormholes in de Sitter space

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chen, Pisin; Hu, Yao-Chieh; Yeom, Dong-han

Here, we investigate Euclidean wormholes in Einstein gravity with a massless scalar field in de Sitter space. Euclidean wormholes are possible due to the analytic continuation of the time as well as complexification of fields, where we need to impose the classicality after the Wick-rotation to the Lorentzian signatures. Furthermore, we prefer wormholes for some parameters, rather than Hawking-Moss instantons, and hence wormholes can be more fundamental than Hawking-Moss type instantons. Euclidean wormholes can be interpreted in three ways: (1) classical big bounce, (2) either tunneling from a small to a large universe or a creation of a collapsing andmore » an expanding universe from nothing, and (3) either a transition from a contracting to a bouncing phase or a creation of two expanding universes from nothing. These various interpretations shed some light on challenges of singularities. In addition, these will help to understand tensions between various kinds of quantum gravity theories.« less

Impurity trapped excitons under high hydrostatic pressure

NASA Astrophysics Data System (ADS)

Grinberg, Marek

2013-09-01

Paper summarizes the results on pressure effect on energies of the 4fn → 4fn and 4fn-15d1 → 4fn transitions as well as influence of pressure on anomalous luminescence in Lnα+ doped oxides and fluorides. A model of impurity trapped exciton (ITE) was developed. Two types of ITE were considered. The first where a hole is localized at the Lnα+ ion (creation of Ln(α+1)+) and an electron is attracted by Coulomb potential at Rydberg-like states and the second where an electron captured at the Lnα+ ion (creation of Ln(α-1)+) and a hole is attracted by Coulomb potential at Rydberg-like states. Paper presents detailed analysis of nonlinear changes of energy of anomalous luminescence of BaxSr1-xF2:Eu2+ (x > 0.3) and LiBaF3:Eu2+, and relate them to ITE-4f65d1 states mixing.

Helicobacter pylori virulence factors in relation to gastrointestinal diseases in Iran.

PubMed

Safaralizadeh, Reza; Dastmalchi, Narges; Hosseinpourfeizi, MohammadAli; Latifi-Navid, Saeid

2017-04-01

Helicobacter pylori as an important pathogenic bacterium that colonizes in gastric mucosa, is one of the causative agents in development of some types of gastric diseases, such as chronic active gastritis, peptic ulcer disease (PUD) and gastric cancer (GC). In this review, the aim is studying different genotypes of H. pylori, and the extent of their participation in the pathogenesis of this bacterium which creates gastroduodenal disorders. Some genotypes of H. pylori have a major role in creation of gastroduodenal diseases, whereas some other genotypes of the bacterium do not cause gastric diseases in Iran. It was also reported that some genotypes of this bacterium in different conditions and among different ethnic groups demonstrate different effectiveness. Role of genotypes of H. pylori in creation of gastroduodenal diseases is different among various regions and ethnic groups of Iran. Copyright © 2017 Elsevier Ltd. All rights reserved.

Migration, Business Formation, and the Informal Economy in Urban Mexico

PubMed Central

Riosmena, Fernando

2013-01-01

Although the informal economy has grown rapidly in several developing nations, and migration and informality may be related to similar types of credit constraints and market failures, previous research has not systematically attempted to identify if migrant households are more likely to start informal and formal businesses alike and if this association varies across local contexts. We examine the relationship between prior U.S. migration and the creation of both formal and informal businesses in urban Mexico using several criteria to indirectly assess sector location. We use data from 56 communities from the Mexican Migration Project to estimate multilevel survival and nonmultilevel competing risk models predicting the likelihood of informal, formal, and no business formation. The recent return migration of the household head is strongly associated with informal business creation, particularly in economically dynamic areas. On the other hand, migrants are only marginally more likely to start formal businesses in highly economically dynamic sending areas. PMID:23721676

Value Co-creation from the Consumer Perspective

NASA Astrophysics Data System (ADS)

Baron, Steve; Warnaby, Gary

The paper provides the basis for a classification of organizational operant resources as seen from a customer perspective. It facilitates, particularly, research and further understanding of Foundational Premise 9 (FP9) of the service-dominant logic of marketing (i.e. all social and economic actors are resource integrators), and suggests areas for more focused research on other foundational premises relating to value co-creation. It is based on research undertaken for, and with, the British Library, and offers an alternative research approach to the more conventional ­customer satisfaction survey in order to ascertain value from a ­consumer perspective.

Coastal resource and sensitivity mapping of Vietnam

DOE Office of Scientific and Technical Information (OSTI.GOV)

Odin, L.M.

1997-08-01

This paper describes a project to establish a relationship between environmental sensitivity (primarily to oil pollution) and response planning and prevention priorities for Vietnamese coastal regions. An inventory of coastal environmental sensitivity and the creation of index mapping was performed. Satellite and geographical information system data were integrated and used for database creation. The database was used to create a coastal resource map, coastal sensitivity map, and a field inventory base map. The final coastal environment sensitivity classification showed that almost 40 percent of the 7448 km of mapped shoreline has a high to medium high sensitivity to oil pollution.

N.G. Basov and early works on semiconductor lasers at P.N. Lebedev Physics Institute

DOE Office of Scientific and Technical Information (OSTI.GOV)

Eliseev, P G

2012-12-31

A survey is presented of works on creation and investigation of semiconductor lasers during 1957 - 1977 at the P.N. Lebedev Physics Institute. Many of these works were initiated by N.G. Basov, starting from pre-laser time, when N.G. Basov and his coworkers formulated principal conditions of creation of lasers on interband transitions in semiconductors. Main directions of further works were diode lasers based on various materials and structures, their characteristics of output power, high-speed operation and reliability. (special issue devoted to the 90th anniversary of n.g. basov)

[Creation of expert centers on endometriosis].

PubMed

Daraï, Emile; Bendifallah, Sofiane; Chabbert-Buffet, Nathalie; Golfier, François

2017-12-01

Endometriosis is a frequent pathology with a high incidence of deep infiltrating endometriosis and complex forms that can affect 20% of patients with endometriosis. The incidence of infertility associated with endometriosis can reach 50%. The complexity of care requires the creation of expert centers working in networks with general practitioners. Criteria for defining these expert centers are being drawn up, based on structural criteria (multidisciplinary consultation meeting), links with medical assistance structures for procreation and activity criteria for severe and complex forms (number of interventions per center and per surgeon). Copyright © 2017. Published by Elsevier Masson SAS.

Testing the Digital Thread in Support of Model-Based Manufacturing and Inspection

PubMed Central

Hedberg, Thomas; Lubell, Joshua; Fischer, Lyle; Maggiano, Larry; Feeney, Allison Barnard

2016-01-01

A number of manufacturing companies have reported anecdotal evidence describing the benefits of Model-Based Enterprise (MBE). Based on this evidence, major players in industry have embraced a vision to deploy MBE. In our view, the best chance of realizing this vision is the creation of a single “digital thread.” Under MBE, there exists a Model-Based Definition (MBD), created by the Engineering function, that downstream functions reuse to complete Model-Based Manufacturing and Model-Based Inspection activities. The ensemble of data that enables the combination of model-based definition, manufacturing, and inspection defines this digital thread. Such a digital thread would enable real-time design and analysis, collaborative process-flow development, automated artifact creation, and full-process traceability in a seamless real-time collaborative development among project participants. This paper documents the strengths and weaknesses in the current, industry strategies for implementing MBE. It also identifies gaps in the transition and/or exchange of data between various manufacturing processes. Lastly, this paper presents measured results from a study of model-based processes compared to drawing-based processes and provides evidence to support the anecdotal evidence and vision made by industry. PMID:27325911

Yet Another Role for Team Building and Work Motivation -Enabler of Knowledge Creation and Knowledge Sharing

DTIC Science & Technology

2002-06-01

team socialising , and finally, goal alignment. The findings strongly suggest that there is a closely coupled relationship between effectiveness of...affiliation, gender , rank, whether military or civilian, work location, and duration of placement. The main advantage of this type of sampling was that it...Goal Alignment *Communication Climate *Recognition & Reward * Socialising *Induction *Mentoring & Buddying *Career Management *Posting & Promotion

Cracking the finger code: an interview with CCR’s Susan Mackem | Center for Cancer Research

Cancer.gov

The creation of the digits in our hand—the thumb, index-middle-ring fingers and pinky—begins early in development, but little is known about the exact programming that occurs to produce the different digit types. Investigators in the Cancer and Developmental Biology Laboratory, (CDBL), provide the first genetic evidence of how the tuning of signals sets digit identity by

The Evolving National Information Network: Background and Challenges. A Report of the Technology Assessment Advisory Committee to the Commission on Preservation and Access.

ERIC Educational Resources Information Center

Van Houweling, Douglas E.; McGill, Michael J.

The rapidly developing and changing networking and telecommunications environment now being implemented in the United States and across the globe is explored. The creation of a flexible and inexpensive digital network allowing instantaneous access by any individual to information of any type is now within our grasp. A primer on the technology…

Release of Suppressed Red Spruce Using Canopy Gap Creation--Ecological Restoration in the Central Appalachians

Treesearch

J.S. Rentch; W.M. Ford; Thomas Schuler; Jeff Palmer; C.A. Diggins

2016-01-01

Red spruce (Picea rubens) and red spruce-northern hardwood mixed stands once covered as much as 300,000 ha in the Central Appalachians, but now comprise no more than 21,000 ha. Recently, interest in restoration of this forest type has increased because red spruce forests provide habitat for a number of rare animal species. Our study reports the...

Federally Created Entities: An Overview of Key Attributes. Report to the Ranking Member, Committee on Finance, U.S. Senate. GAO-10-97

ERIC Educational Resources Information Center

Ragland, Susan; Poling, Susan A.

2009-01-01

Over the years, Congress has created or authorized the creation of numerous entities to carry out federal programs and further public purposes. These federally created entities can be categorized into several types and serve a variety of missions. They are subject to varying governance, accountability, and transparency requirements through which…

Oxidation-mediated chitosan as additives for creation of chitosan aerogels with diverse three-dimensional interconnected skeletons

NASA Astrophysics Data System (ADS)

Zhang, Sizhao; Feng, Jian; Feng, Junzong; Jiang, Yonggang

2017-02-01

Naturally occurring polymer-based aerogels have myriad practical utilizations due to environmentally benign and fruitful resources. However, engineering morphology-controllable biomass aerogels still represents a great challenge. Here we present a facile solution to synthesize chitosan aerogels having distinguished textures by reacting oxidized chitosan with formaldehyde and chitosan sol. In more detail, chitosan was chemically oxidized using two types of oxidation agents such as ammonium persulphate (SPD) and sodium periodate (APS) to obtain corresponding oxidized chitosan, subsequently cross-linked with chitosan solution containing formaldehyde to harvest SPD-oxidized chitosan aerogels (SCAs) and APS-SPD-oxidized ones (ASCAs) after aging, solvent exchange and supercritical drying processes. We found that the morphologies of as-prepared chitosan aerogels are strongly dependent upon the oxidation pattern towards chitosan. The structural textures of SCAs and ASCAs appear nanoflake-like and nanofiber-like structures, which may be related to spatial freedom of active groups located in chitosan. Selected area electron diffraction analysis reveals that the crystalline properties of chitosan aerogels generally appear the serious deterioration comparing to raw chitosan owing to their interconnected skeletal structure formation. The occurrence of characteristic groups displays cross-linked chain construction by using chemical state measurements such as FT-IR and XPS. Further, a plausible mechanism for controlling morphology of chitosan aerogels is also established. This new family of method for creation of chitosan aerogels may open up a perspective for biomass aerogels with controllable textures.

Preoperative ultrasound still valuable for radio-cephalic arteriovenous fistula creation?

PubMed

Pajek, Jernej; Malovrh, Marko

2017-03-06

Radio-cephalic arteriovenous fistula is a prototype hemodialysis access with small incidences of infection and distal ischemia, it spares proximal veins for future access use and it helps in the maturation of veins that may be used for more proximal access creations. This access type is prone to higher early failure rates compared to more proximal fistulas and there are unsolved uncertainties regarding exact ultrasound parameters predictive of fistula outcome. Evolution of ultrasound use has yielded several functional parameters that can be measured in addition to anatomical lumen sizes, which remain core parameters on which the decision to construct fistula in radio-cephalic forearm position is based. We propose to use arterial hyperemic response and wall morphology to aid in this decision when radial artery diameter falls in the interval with predictive uncertainty of 1.6-1.9 mm and to use venous flow pattern, respiratory variation, radial artery status and possibly venous distensibility when cephalic vein augmented diameter lies in the borderline interval of 2-2.4 mm. Ultrasound preoperative mapping and planning should be followed by expert surgical technique and several technique modifications of the classical end-to-side approach are possible to enhance operation outcome and diminish the incidence of stenosis most often present at juxta-anastomotic location. In our experience radio-cephalic arteriovenous fistula remains the golden standard for hemodialysis access and preoperative ultrasound the single best imaging modality to plan the operation and predict its success.

Phyllotactic arrangements of optical elements

NASA Astrophysics Data System (ADS)

Horacek, M.; Meluzin, P.; Kratky, S.; Matejka, M.; Kolarik, V.

2017-05-01

Phyllotaxy studies arrangements of biological entities, e.g. a placement of seeds in the flower head. Vogel (1979) presented a phyllotactic model based on series of seeds ordered along a primary spiral. This arrangement allows each seed to occupy the same area within a circular flower head. Recently, a similar arrangement of diffraction primitives forming a planar relief diffractive structure was presented. The planar relief structure was used for benchmarking and testing purposes of the electron beam writer patterning process. This contribution presents the analysis of local periods and azimuths of optical phyllotactic arrangements. Two kinds of network characteristic triangles are introduced. If the discussed planar structure has appropriate size and density, diffraction of the incoming light creates characteristic a phyllotactic diffraction pattern. Algorithms enabling the analysis of such behavior were developed and they were validated by fabricated samples of relief structures. Combined and higher diffraction orders are also analyzed. Different approaches enabling the creation of phyllotactic diffractive patterns are proposed. E-beam lithography is a flexible technology for various diffraction gratings origination. The e-beam patterning typically allows for the creation of optical diffraction gratings in the first diffraction order. Nevertheless, this technology enables also more complex grating to be prepared, e.g. blazed gratings and zero order gratings. Moreover, the mentioned kinds of gratings can be combined within one planar relief structure. The practical part of the presented work deals with the nano patterning of such structures by using two different types of the e-beam pattern generators.

Medical research--a comparative study of the situation in the RSA and in certain other countries.

PubMed

Brink, A J

1983-02-05

Research as a whole, with medical research as part thereof, is supported by organizational systems which differ in different countries. The basis for research support is nearly always one of two types: projects (short-term research) conducted by individuals, or programme research (a more extended form) carried out by a number of people in a defined field and under the direction of a person uniquely suited to lead the research. The other important form of research undertaking is one of national importance which assumes dimensions necessitating the creation of specific facilities in the form of buildings, research equipment and a staffing establishment (usually termed an 'institute'). Certain aspects relating to medical research as seen in other countries could well be adapted to our own needs, such as the introduction of research work communities (as found in Holland), and the establishment of priority research programmes in order to develop areas of neglect (as done in Germany). Adjustments can also be made to our training programmes and bursary schemes. In particular, attention can be paid to the re-employment of active research workers who have reached retirement age, and to the creation of full-time research posts in different categories at universities. In whatever manner our available research funds are calculated for comparison with those available elsewhere, whether based on money available per capita, size in relation to other research programmes or percentage of gross national product, the position of South Africa appears to be embarrassingly inferior.

Perspective: acts of interpretation: a philosophical approach to using creative arts in medical education.

PubMed

Kumagai, Arno K

2012-08-01

Medical educators have used the visual arts for a variety of instrumental purposes, such as sharpening trainees' skills in observation, description, critical thinking, and communication. The arts have also served as means to more humanistic ends-that is, as a mode of self-care for house officers coping with grief and as a medium for reflecting on the meaning of illness and the nature of doctoring. More generally, art can serve as an expression of identity, as a form of social critique, and as a means to develop a sense of community of shared values. At the University of Michigan Medical School, the creation of original artwork (visual or otherwise) has been a major part of the Family Centered Experience, a longitudinal learning activity based on the stories that patient-volunteers tell of living with chronic illness. The purpose of this article is to explore how the creation of original art may serve as concrete evidence of the types of tacit learning and understanding that students gain through human interactions in medicine. The evidence of learning is not achieved via behaviorist notions of "demonstrating competence"; instead, student interpretive projects are visual or musical expressions of the affective, experiential, cognitive, and existential lessons students have learned through their long-term relationships with patient-volunteers. The overall aim of this article is to provide additional theoretical foundations, as well as practical information, that may guide the incorporation of the humanities and arts into the training of physicians.

How Co-Creation Helped Address Hierarchy, Overwhelmed Patients, and Conflicts of Interest in Health Care Quality and Safety.

PubMed

Israilov, Sigal; Cho, Hyung J

2017-11-01

Co-creation is health professionals' and systems' development of health care together with patients and families. Such collaborations yield an exchange of values, ideas, and priorities that can individualize care for each patient. Co-creation has been discussed interchangeably with co-production and shared decision making; this article explores co-creation through the lens of quality improvement. Although there are barriers to co-creation including physician autonomy, patient overwhelm, and conflicts of interest, co-creation has been shown to promote patient engagement, peer learning, and improved outcomes. Further research is needed in co-creation for systems improvement. © 2017 American Medical Association. All Rights Reserved.

Determination of the spectral dependence of reduced scattering and quantitative second-harmonic generation imaging for detection of fibrillary changes in ovarian cancer

NASA Astrophysics Data System (ADS)

Campbell, Kirby R.; Tilbury, Karissa B.; Campagnola, Paul J.

2015-03-01

Here, we examine ovarian cancer extracellular matrix (ECM) modification by measuring the wavelength dependence of optical scattering measurements and quantitative second-harmonic generation (SHG) imaging metrics in the range of 800-1100 nm in order to determine fibrillary changes in ex vivo normal ovary, type I, and type II ovarian cancer. Mass fractals of the collagen fiber structure is analyzed based on a power law correlation function using spectral dependence measurements of the reduced scattering coefficient μs' where the mass fractal dimension is related to the power. Values of μs' are measured using independent methods of determining the values of μs and g by on-axis attenuation measurements using the Beer-Lambert Law and by fitting the angular distribution of scattering to the Henyey-Greenstein phase function, respectively. Quantitativespectral SHG imaging on the same tissues determines FSHG/BSHG creation ratios related to size and harmonophore distributions. Both techniques probe fibril packing order, but the optical scattering probes structures of sizes from about 50-2000 nm where SHG imaging - although only able to resolve individual fibers - builds contrast from the assembly of fibrils. Our findings suggest that type I ovarian tumor structure has the most ordered collagen fibers followed by normal ovary then type II tumors showing the least order.

7 CFR 1703.301 - Policy.

Code of Federal Regulations, 2010 CFR

2010-01-01

... is RUS's policy to encourage borrowers to invest in and promote rural development and rural job creation projects that are based on sound economic and financial analyses. Borrowers are encouraged to use...

Computer Synthesis Approaches of Hyperboloid Gear Drives with Linear Contact

NASA Astrophysics Data System (ADS)

Abadjiev, Valentin; Kawasaki, Haruhisa

2014-09-01

The computer design has improved forming different type software for scientific researches in the field of gearing theory as well as performing an adequate scientific support of the gear drives manufacture. Here are attached computer programs that are based on mathematical models as a result of scientific researches. The modern gear transmissions require the construction of new mathematical approaches to their geometric, technological and strength analysis. The process of optimization, synthesis and design is based on adequate iteration procedures to find out an optimal solution by varying definite parameters. The study is dedicated to accepted methodology in the creation of soft- ware for the synthesis of a class high reduction hyperboloid gears - Spiroid and Helicon ones (Spiroid and Helicon are trademarks registered by the Illinois Tool Works, Chicago, Ill). The developed basic computer products belong to software, based on original mathematical models. They are based on the two mathematical models for the synthesis: "upon a pitch contact point" and "upon a mesh region". Computer programs are worked out on the basis of the described mathematical models, and the relations between them are shown. The application of the shown approaches to the synthesis of commented gear drives is illustrated.

Analyzing Forces on Amusement Park Rides with Mobile Devices

NASA Astrophysics Data System (ADS)

Vieyra, Rebecca E.; Vieyra, Chrystian

2014-03-01

Mobile device accelerometers are a simple and easy way for students to collect accurate and detailed data on an amusement park ride. The resulting data can be graphed to assist in the creation of force diagrams to help students explain their physical sensations while on the ride. This type of activity can help students overcome some of the conceptual difficulties often associated with understanding centripetal force and typical "elevator-type problems" that are inherent in so many amusement park rides that move, lift, and drop riders. This article provides some sample data and examples from a visit to Six Flags Great America.

The Development of German Army Airplanes During the War

NASA Technical Reports Server (NTRS)

Wilhelm, Hoff

1921-01-01

The author, who was a captain of the Reserves in the Technical Department of the Aviation Division (Board of Airplane Experts) during the war, shows what means were taken for the creation of new airplane types and what tests were employed for trying out their flying properties, capacities and structural reliability. The principal representative types of each of the classes of airplanes are described and the characteristics of the important structural parts are discussed. Data regarding the number of airplanes at the front and the flying efficiency of the various classes of airplanes are given.

[Surgical learning curve for creation of vascular accesses for haemodialysis: value of medico-radio-surgical collaboration].

PubMed

Van Glabeke, Emmanuel; Belenfant, Xavier; Barrou, Benoît; Adhemar, Jean-Pierre; Laedrich, Joëlle; Mavel, Marie-Christine; Challier, Emmanuel

2005-04-01

Creation of a vascular access (VA) for haemodialysis is a surgical procedure which comprises a failure rate related to the quality of the vessels and the operator's experience. The authors report the first 2 years of a young urologist's experience with this procedure in a local hospital in collaboration with the nephrology team. Patients undergoing creation of VA were divided into 2 chronological groups. The patient's age and gender, the cause of renal failure, the presence of diabetes, clinical examination of the upper limb, preoperative assessment of upper limb vessels, the type of anaesthesia, the operating time and the start of dialysis after the operation, as well as the functional results of the VA at 6 months were studied. Results concerning the patients of the first period were discussed by the operator and the nephrology team. During the first 9 months, 28 patients were operated, corresponding to 36 operations including 32 direct fistulas. Over the following 15 months, 61 patients were operated, with the creation of 63 VAs, including 55 direct fistulas. The failure rate (thrombosis or non-functioning VA) decreased from 32.1% to 11.1% (p=0.07), while the 2 groups were globally comparable. Evaluation of a new surgical procedure shows a number of failures, as for all learning curves. However, it helps to improve the results. Collaboration with nephrologists must comprise a discussion allowing the acceptance of certain failures, as they reflect compliance with a strategy of preservation of the vascular capital and a rational attempt to avoid a non-essential proximal access or bypass graft. The support of a motivated radiology team (preoperative assessment and management of complications) and the assistance of a more experienced operator are essential.

The sleeve method for creation of radiocephalic arteriovenous fistulas in patients with calcified vessels.

PubMed

Gołębiowski, Tomasz; Weyde, Wacław; Letachowicz, Krzysztof; Kusztal, Mariusz; Augustyniak-Bartosik, Hanna; Penar, Jan; Madziarska, Katarzyna; Zmonarski, Sławomir; Krajewska, Magdalena; Klinger, Marian

2017-09-11

Creation of an arteriovenous fistula (AVF) in patients with advanced atherosclerotic changes of the artery is often a challenge for the physician due to difficulties in suturing the vein to the side of the frangible artery. The sleeve technique relies on advancing the end of the artery into the lumen of the vein and protecting the anastomosis by adventitial sutures. The sleeve technique was performed in 23 patients with chronic kidney disease stage IV and V and included hemodialysis patients. Their mean age was 60.8 ± 14.8 years and hemodialysis treatment time 49.8 ± 40.2 months. The most frequent causes of chronic kidney disease are ischemic nephropathy (43%, n = 10) and type l diabetes (21%, n = 5). Only patients with extremely advanced atherosclerotic were recruited and analyzed. The primary patency rate was 67%, 59%, 44% and 28% at 6, 12, 24, and 36 months, respectively. The secondary patency rate was 67%, 61%, 50% and 37% at 6, 12, 24, and 36 months, respectively. In three patients the AVF failed directly after the operation. Delayed fistula failure occurred in seven patients. The overall success in the creation of a functioning fistula was achieved in 15 of the 23 patients (65%). No serious complications were observed. In patients with calcified atherosclerotic plaques, which constitute a barrier or make it difficult to suture the vein to the side of the artery, the sleeve method may be considered as an alternative before abandoning the creation of a fistula on the forearm. The technique is much simpler than the standard end-to-side or side-to-side anastomosis.

Experimental Percutaneous Extrahepatic Portacaval Shunt Creation by Transjugular Approach in Swine

DOE Office of Scientific and Technical Information (OSTI.GOV)

Seong, Chang Kyu; Pavcnik, Dusan, E-mail: pavcnikd@ohsu.edu; Uchida, Barry T.

2005-06-15

The purpose of the study was to evaluate the feasibility of the creation of a percutaneous extrahepatic portacaval shunt (PEPS) in swine by a transjugular approach and to find a suitable stent-graft to use in PEPS. In 12 swine, the extrahepatic portal vein (PV) was entered from the inferior vena cava (IVC) by a needle system introduced from the transjugular approach. A catheter introduced through the transhepatic approach served as a target. Five types of stent-graft consisting of homemade Z stents and a polytetrafluoethylene cover were explored for PEPS creation. Eight animals had follow-up venograms up to 6 weeks ormore » until the shunt became severely stenotic. Gross and histologic examinations were performed after the final follow-up venography. The PV punctures and stent-graft placement were difficult, but the PEPS was established in all animals. In four animals, the stent-graft failed to adequately cover the tract, causing severe hemorrhage. Only two shunts remained patent up to 6 weeks. The other shunts exhibited severe stenosis or occlusion. At gross examination, all shunts traversed the liver parenchyma of the caudate lobe surrounding the IVC. The extravascular PEPS portion was 4 mm to 2 cm long. All shunts entered the PV close to the splenomesenteric junction and exhibited neointimal formation. Shunt stenoses were caused by neointimal hyperplasia and occlusions by a superimposed thrombus. PEPS can be created by the transjugular approach in swine, but only the PV shunt entrance is extrahepatic. None of the tested rigid stent-grafts were suitable for PEPS creation. A short flexible stent-graft with flanged ends is suggested for further exploration.« less

Reconstructive techniques for creation of catheterizable channels: tunneled and nipple valve channels

PubMed Central

Levy, Mya E.

2016-01-01

Cutaneous catheterizable channels allow for continent bladder emptying when an alternate route is desired. The goals of channel creation in the neurogenic bladder population are successful urine elimination, renal preservation, continence and lastly cosmesis. In addition to a particular surgeon’s comfort and experience with a given procedure, individual patient factors such as medical comorbidities, anatomic factors, and occupational function should be central to the selection of a surgical approach. An ideal channel is one that is short, straight, and well supported by associated blood supply and surrounding adventitia, so as to minimize difficulty with catheterization. Two types of channel continence mechanisms are discussed at length in this review—the tunneled channel, and the nipple valve. The appendicovesicostomy (Mitrofanoff), and reconfigured ileum (Yang-Monti) are both tunneled channels. The ileocecal valve is a commonly used nipple valve and provides continence when reinforced. The continent catheterizable ileal cecocystoplasty (CCIC) is an example of this channel technique. This method couples a tapered ileal limb as a catheterizable channel, the ileocecal valve as the continence mechanism, and the cecum and ascending colon as a bladder augmentation. While this procedure has higher perioperative complications relative to a simple tunneled channel, it has increased channel length flexibility and is also coupled with a bladder augment, which is completely performed using one bowel segment. Continent channel creation in adults can improve quality of life and minimize morbidity associated with neurogenic bladder. However, the decision to proceed with creation of a catheterizable channel should be made only after careful consideration of the patient’s medical comorbidities, physical abilities social support, and surgeon experience. PMID:26904419

Elimination of the negative component of the unipolar atrial electrogram as an in vivo marker of transmural lesion creation: acute study in canines.

PubMed

Bortone, Agustín; Brault-Noble, Guillaume; Appetiti, Anthony; Marijon, Eloi

2015-08-01

It has been experimentally shown that elimination of the negative component of the unipolar atrial electrogram (R morphology completion) during radiofrequency applications reflects transmural lesions creation. Subsequently, it has been clinically suggested that such a transmurality can be either irreversible or reversible. The present study is aimed to determine, at the histological level, whether transmural lesions, assessed by R morphology completion, might indeed be reversible in some circumstances or not. In 6 Mongrel hound dogs, superior and inferior vena cavae were isolated and individual lesions were created in the right atrium using radiofrequency energy (30 W/48°C/17 mL/min as presettings and 10g of force in average) under CARTO guidance. Five types of lesions were created; R+0: termination of ablation at the time of R morphology completion; R+5, R+10, or R+20: extension of ablation for 5, 10, or 20 seconds, respectively, after R morphology achievement; and conventional: radiofrequency applications lasting 30 seconds irrespective of the atrial electrogram modification. All conventional, R+5, R+10, and R+20 lesions were necrotic and transmural, whereas some R+0 lesions were not (comprising a part of necrosis and a part of reversible cell damage). Interestingly, surrounding organ injuries were observed after conventional, R+10, and R+20 radiofrequency applications but were not observed after R+0 and R+5 applications. Elimination of the negative component of the unipolar atrial electrogram reflects, in general, irreversible transmural necrosis creation. In some cases, however, it translates transmural lesion only (with potential reversibility) likely related to transient cell damage creation. © 2015 American Heart Association, Inc.

Storytelling Molas.

ERIC Educational Resources Information Center

Clark, Sylvia T.

1998-01-01

Recounts the creation by fifth- and sixth-grade students of their own personal "molas," based on the fabric art form of the Cuna Indians of the San Blas Islands off the coast of Panama. Tells how students created their designs based around a central image surrounded by geometric patterns and colors. (DSK)

A Computer Program for the Management of Prescription-Based Problems.

ERIC Educational Resources Information Center

Cotter, Patricia M.; Gumtow, Robert H.

1991-01-01

The Prescription Management Program, a software program using Apple's HyperCard on a MacIntosh, was developed to simplify the creation, storage, modification, and general management of prescription-based problems. Pharmacy instructors may customize the program to serve their individual teaching needs. (Author/DB)

Palaeo-sea-level and palaeo-ice-sheet databases: problems, strategies, and perspectives

NASA Astrophysics Data System (ADS)

Düsterhus, André; Rovere, Alessio; Carlson, Anders E.; Horton, Benjamin P.; Klemann, Volker; Tarasov, Lev; Barlow, Natasha L. M.; Bradwell, Tom; Clark, Jorie; Dutton, Andrea; Gehrels, W. Roland; Hibbert, Fiona D.; Hijma, Marc P.; Khan, Nicole; Kopp, Robert E.; Sivan, Dorit; Törnqvist, Torbjörn E.

2016-04-01

Sea-level and ice-sheet databases have driven numerous advances in understanding the Earth system. We describe the challenges and offer best strategies that can be adopted to build self-consistent and standardised databases of geological and geochemical information used to archive palaeo-sea-levels and palaeo-ice-sheets. There are three phases in the development of a database: (i) measurement, (ii) interpretation, and (iii) database creation. Measurement should include the objective description of the position and age of a sample, description of associated geological features, and quantification of uncertainties. Interpretation of the sample may have a subjective component, but it should always include uncertainties and alternative or contrasting interpretations, with any exclusion of existing interpretations requiring a full justification. During the creation of a database, an approach based on accessibility, transparency, trust, availability, continuity, completeness, and communication of content (ATTAC3) must be adopted. It is essential to consider the community that creates and benefits from a database. We conclude that funding agencies should not only consider the creation of original data in specific research-question-oriented projects, but also include the possibility of using part of the funding for IT-related and database creation tasks, which are essential to guarantee accessibility and maintenance of the collected data.

(U) An Analytic Examination of Piezoelectric Ejecta Mass Measurements

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tregillis, Ian Lee

2017-02-02

Ongoing efforts to validate a Richtmyer-Meshkov instability (RMI) based ejecta source model [1, 2, 3] in LANL ASC codes use ejecta areal masses derived from piezoelectric sensor data [4, 5, 6]. However, the standard technique for inferring masses from sensor voltages implicitly assumes instantaneous ejecta creation [7], which is not a feature of the RMI source model. To investigate the impact of this discrepancy, we define separate “areal mass functions” (AMFs) at the source and sensor in terms of typically unknown distribution functions for the ejecta particles, and derive an analytic relationship between them. Then, for the case of single-shockmore » ejection into vacuum, we use the AMFs to compare the analytic (or “true”) accumulated mass at the sensor with the value that would be inferred from piezoelectric voltage measurements. We confirm the inferred mass is correct when creation is instantaneous, and furthermore prove that when creation is not instantaneous, the inferred values will always overestimate the true mass. Finally, we derive an upper bound for the error imposed on a perfect system by the assumption of instantaneous ejecta creation. When applied to shots in the published literature, this bound is frequently less than several percent. Errors exceeding 15% may require velocities or timescales at odds with experimental observations.« less

Practical Implementation of Semi-Automated As-Built Bim Creation for Complex Indoor Environments

NASA Astrophysics Data System (ADS)

Yoon, S.; Jung, J.; Heo, J.

2015-05-01

In recent days, for efficient management and operation of existing buildings, the importance of as-built BIM is emphasized in AEC/FM domain. However, fully automated as-built BIM creation is a tough issue since newly-constructed buildings are becoming more complex. To manage this problem, our research group has developed a semi-automated approach, focusing on productive 3D as-built BIM creation for complex indoor environments. In order to test its feasibility for a variety of complex indoor environments, we applied the developed approach to model the `Charlotte stairs' in Lotte World Mall, Korea. The approach includes 4 main phases: data acquisition, data pre-processing, geometric drawing, and as-built BIM creation. In the data acquisition phase, due to its complex structure, we moved the scanner location several times to obtain the entire point clouds of the test site. After which, data pre-processing phase entailing point-cloud registration, noise removal, and coordinate transformation was followed. The 3D geometric drawing was created using the RANSAC-based plane detection and boundary tracing methods. Finally, in order to create a semantically-rich BIM, the geometric drawing was imported into the commercial BIM software. The final as-built BIM confirmed that the feasibility of the proposed approach in the complex indoor environment.

A biosensor based on electroactive dipyrromethene-Cu(II) layer deposited onto gold electrodes for the detection of antibodies against avian influenza virus type H5N1 in hen sera.

PubMed

Jarocka, Urszula; Sawicka, Róża; Stachyra, Anna; Góra-Sochacka, Anna; Sirko, Agnieszka; Zagórski-Ostoja, Włodzimierz; Sączyńska, Violetta; Porębska, Anna; Dehaen, Wim; Radecki, Jerzy; Radecka, Hanna

2015-10-01

This paper describes the development of a biosensor for the detection of anti-hemagglutinin antibodies against the influenza virus hemagglutinin. The steps of biosensor fabrications are as follows: (i) creation of a mixed layer containing the thiol derivative of dipyrromethene and 4-mercapto-1-butanol, (ii) complexation of Cu(II) ions, (iii) oriented immobilization of the recombinant histidine-tagged hemagglutinin, and (iv) filling free spaces with bovine serum albumin. The interactions between recombinants hemagglutinin from the highly pathogenic avian influenza virus type H5N1 and anti-hemagglutinin H5 monoclonal antibodies were explored with Osteryoung square-wave voltammetry. The biosensor displayed a good detection limit of 2.4 pg/mL, quantification limit of 7.2 pg/mL, and dynamic range from 4.0 to 100.0 pg/mL in buffer. In addition, this analytical device was applied for the detection of antibodies in hen sera from individuals vaccinated and non-vaccinated against the avian influenza virus type H5N1. The limit of detection for the assay was the dilution of sera 1: 7 × 10(6), which is about 200 times better than the enzyme-linked immunosorbent assay.

Quantum junction solar cells.

PubMed

Tang, Jiang; Liu, Huan; Zhitomirsky, David; Hoogland, Sjoerd; Wang, Xihua; Furukawa, Melissa; Levina, Larissa; Sargent, Edward H

2012-09-12

Colloidal quantum dot solids combine convenient solution-processing with quantum size effect tuning, offering avenues to high-efficiency multijunction cells based on a single materials synthesis and processing platform. The highest-performing colloidal quantum dot rectifying devices reported to date have relied on a junction between a quantum-tuned absorber and a bulk material (e.g., TiO(2)); however, quantum tuning of the absorber then requires complete redesign of the bulk acceptor, compromising the benefits of facile quantum tuning. Here we report rectifying junctions constructed entirely using inherently band-aligned quantum-tuned materials. Realizing these quantum junction diodes relied upon the creation of an n-type quantum dot solid having a clean bandgap. We combine stable, chemically compatible, high-performance n-type and p-type materials to create the first quantum junction solar cells. We present a family of photovoltaic devices having widely tuned bandgaps of 0.6-1.6 eV that excel where conventional quantum-to-bulk devices fail to perform. Devices having optimal single-junction bandgaps exhibit certified AM1.5 solar power conversion efficiencies of 5.4%. Control over doping in quantum solids, and the successful integration of these materials to form stable quantum junctions, offers a powerful new degree of freedom to colloidal quantum dot optoelectronics.

[Report of the NEDO project "Research and development to promote the creation and utilization of an intellectual infrastructure: development of reference materials for laboratory medicine" "Development of pure substance-type certified reference materials"].

PubMed

Takatsu, Akiko

2009-06-01

There is an increasing demand to establish a metrological traceability system for in vitro diagnostics and medical devices. Pure substance-type reference materials are playing key roles in metrological traceability, because they form the basis for many traceability chains in chemistry. The National Metrology Institute of Japan (NMIJ), in the National Institute of Advanced Industrial Science and Technology (AIST), has been developing purity-certified reference materials (CRMs) in this field, such as cholesterol, creatinine, and urea. In the New Energy and Industrial Technology Development Organization (NEDO) project, entitled: "Research and Development to Promote the Creation and Utilization of an Intellectual Infrastructure: Development of Reference Materials for Laboratory Medicine", several pure substance-type CRMs were developed. For a pure protein solution CRM, amino acid analysis and nitrogen determination were chosen as the certification methods. The development and certification processes for the C-reactive protein (CRP) solution CRM were completed, with the recombinant human CRP solution as a candidate material. This CRP solution CRM is now available as NMIJ CRM. For cortisol CRM, a purified candidate material and highly pure primary reference material were prepared. Each impure compound in the materials was identified and quantified. The pure cortisol CRM will be available in 2009. These two CRMs provide a traceability link between routine clinical methods and the SI unit.

Defensive Cyber Battle Damage Assessment Through Attack Methodology Modeling

DTIC Science & Technology

2011-03-25

ASL Creation ............................................................... 68 3.3.4. Evidence Evaluation and EML Creation...90 4.2.3. COA Analysis and ASL Creation ............................................................... 92 4.2.4. Evidence Evaluation and EML ...Evidence Evaluation and EML Creation. .................................................... 70 18. DCBDA Forensic Analysis

Prognostic capability of different liver disease scoring systems for prediction of early mortality after transjugular intrahepatic portosystemic shunt creation.

PubMed

Gaba, Ron C; Couture, Patrick M; Bui, James T; Knuttinen, M Grace; Walzer, Natasha M; Kallwitz, Eric R; Berkes, Jamie L; Cotler, Scott J

2013-03-01

To compare the performance of various liver disease scoring systems in predicting early mortality after transjugular intrahepatic portosystemic shunt (TIPS) creation. In this single-institution retrospective study, eight scoring systems were used to grade liver disease in 211 patients (male-to-female ratio = 131:80; mean age, 54 y) before TIPS creation from 1999-2011. Scoring systems included bilirubin level, Child-Pugh (CP) score, Model for End-Stage Liver Disease (MELD) and Model for End-Stage Liver Disease sodium (MELD-Na) score, Emory score, prognostic index (PI), Acute Physiology and Chronic Health Evaluation (APACHE) 2 score, and Bonn TIPS early mortality (BOTEM) score. Medical record review was used to identify 30-day and 90-day clinical outcomes. The relationship of scoring parameters with mortality outcomes was assessed with multivariate analysis, and the relative ability of systems to predict mortality after TIPS creation was evaluated by comparing area under receiver operating characteristic (AUROC) curves. TIPS were successfully created for variceal hemorrhage (n = 121), ascites (n = 72), hepatic hydrothorax (n = 15), and portal vein thrombosis (n = 3). All scoring systems had a significant association with 30-day and 90-day mortality (P<.050 in each case) on multivariate analysis. Based on 30-day and 90-day AUROC, MELD (0.878, 0.816) and MELD-Na (0.863, 0.823) scores had the best capability to predict early mortality compared with bilirubin (0.786, 0.749), CP (0.822, 0.771), Emory (0.786, 0.681), PI (0.854, 0.760), APACHE 2 (0.836, 0.735), and BOTEM (0.798, 0.698), with statistical superiority over bilirubin, Emory, and BOTEM scores. Several liver disease scoring systems have prognostic value for early mortality after TIPS creation. MELD and MELD-Na scores most effectively predict survival after TIPS creation. Copyright © 2013. Published by Elsevier Inc.

OntoCR: A CEN/ISO-13606 clinical repository based on ontologies.

PubMed

Lozano-Rubí, Raimundo; Muñoz Carrero, Adolfo; Serrano Balazote, Pablo; Pastor, Xavier

2016-04-01

To design a new semantically interoperable clinical repository, based on ontologies, conforming to CEN/ISO 13606 standard. The approach followed is to extend OntoCRF, a framework for the development of clinical repositories based on ontologies. The meta-model of OntoCRF has been extended by incorporating an OWL model integrating CEN/ISO 13606, ISO 21090 and SNOMED CT structure. This approach has demonstrated a complete evaluation cycle involving the creation of the meta-model in OWL format, the creation of a simple test application, and the communication of standardized extracts to another organization. Using a CEN/ISO 13606 based system, an indefinite number of archetypes can be merged (and reused) to build new applications. Our approach, based on the use of ontologies, maintains data storage independent of content specification. With this approach, relational technology can be used for storage, maintaining extensibility capabilities. The present work demonstrates that it is possible to build a native CEN/ISO 13606 repository for the storage of clinical data. We have demonstrated semantic interoperability of clinical information using CEN/ISO 13606 extracts. Copyright © 2016 Elsevier Inc. All rights reserved.

The Necessity for Routine Pre-operative Ultrasound Mapping Before Arteriovenous Fistula Creation: A Meta-analysis.

PubMed

Georgiadis, G S; Charalampidis, D G; Argyriou, C; Georgakarakos, E I; Lazarides, M K

2015-05-01

Existing guidelines suggest routine use of pre-operative color Doppler ultrasound (DUS) vessel mapping before the creation of arteriovenous fistulae (AVF); however, there is controversy about its benefit over traditional clinical examination or selective ultrasound use. This was a systematic review and meta-analysis of randomized controlled trials (RCTs) comparing routine DUS mapping before the creation of AVF with patients for whom the decision for AVF placement was based on clinical examination and selective ultrasound use. A search of MEDLINE/PubMed, SCOPUS, and the Cochrane Library was carried out in June 2014. The analyzed outcome measures were the immediate failure rate and the early/midterm adequacy of the fistula for hemodialysis. Additionally, assessment of the methodological quality of the included studies was carried out. Five studies (574 patients) were analyzed. A random effects model was used to pool the data. The pooled odds ratio (OR) for the immediate failure rate was 0.32 (95% confidence interval [CI] 0.17-0.60; p < .01), which was significantly in favor of the DUS mapping group. The pooled OR for the early/midterm adequacy for hemodialysis was 0.66 (95% CI 0.42-1.03; p = .06), with a trend in favor of the DUS mapping group; however, subgroup analysis revealed that routine DUS mapping was more beneficial than selective DUS (p < .05). The available evidence, based mainly on moderate quality RCTs, suggests that the pre-operative clinical examination should always be supplemented with routine DUS mapping before AVF creation. This policy avoids negative surgical explorations and significantly reduces the immediate AVF failure rate. Copyright © 2015 European Society for Vascular Surgery. Published by Elsevier Ltd. All rights reserved.

A Study of the Effectiveness of Web-Based Homework in Teaching Undergraduate Business Statistics

ERIC Educational Resources Information Center

Palocsay, Susan W.; Stevens, Scott P.

2008-01-01

Web-based homework (WBH) Technology can simplify the creation and grading of assignments as well as provide a feasible platform for assessment testing, but its effect on student learning in business statistics is unknown. This is particularly true of the latest software development of Web-based tutoring agents that dynamically evaluate individual…

Value co-creation in healthcare through positive deviance.

PubMed

Zanetti, Cole Anthony; Taylor, Natalie

2016-12-01

To explore how converging fields of co-creation and positive deviance may increase value in healthcare. Informed by research in positive deviance, patient engagement, value co-creation, and quality improvement, we propose a positive deviance approach to co-creation of health. Co-creation has shown to improve health outcomes with regard to multiple health conditions. Positive deviance has also shown to improve outcomes in multiple healthcare and patient community environments. A positive deviance co-creation framework may aid in achieving improved outcomes for patients, care teams and their respective healthcare organizations. Copyright © 2016 Elsevier Inc. All rights reserved.

Effect of traditional plants in Sri Lanka on skin fibroblast cell number.

PubMed

Sano, Katsura; Someya, Takao; Hara, Kotaro; Sagane, Yoshimasa; Watanabe, Toshihiro; Wijesekara, R G S

2018-08-01

This article describes the effects of extracts of several plants collected in Sri Lanka on the cell number of human skin fibroblasts. This study especially focuses on the plants traditionally used in indigenous systems of medicine in Sri Lanka, such as Ayurveda, as described below (English name, "local name in Sri Lanka," scientific name). Bougainvillea plant, "bouganvilla," Bougainvillea grabla (Nature׳s Beauty Creations Ltd., 2014) [1], purple fruited pea eggplant,"welthibbatu," Solanum trilobatum (Nature׳s Beauty Creations Ltd., 2014) [2], country borage plant, "kapparawalliya," Plectranthus amboinicus  (Nature׳s Beauty Creations Ltd., 2014) [3], malabar nut plant, "adhatoda," Justicia adhatoda (Nature׳s Beauty Creations Ltd., 2014) [4], long pepper plant,"thippili," Piper longum (Nature׳s Beauty Creations Ltd., 2014) [5], holy basil plant, "maduruthala," Ocimum tenuiflorum (Nature׳s Beauty Creations Ltd., 2014) [6], air plant, "akkapana," Kalanchoe pinnata (Nature׳s Beauty Creations Ltd., 2014) [7], plumed cockscomb plant, "kiri-henda," Celosia argentea (Nature׳s Beauty Creations Ltd., 2014) [8], neem plant,"kohomba," Azadirachta indica (Nature׳s Beauty Creations Ltd., 2014) [9], emblic myrobalan plant, "nelli," Phyllanthus emblica (Nature׳s Beauty Creations Ltd., 2014) [10]. Human skin fibroblast cells were treated with various concentration of plant extracts (0-3.0%), and the cell viability of cells were detected using calcein assay. The cell viabillity profiles are provided as line graphs.

Visualising Learning Design in LAMS: A Historical View

ERIC Educational Resources Information Center

Dalziel, James

2011-01-01

The Learning Activity Management System (LAMS) provides a web-based environment for the creation, sharing, running and monitoring of Learning Designs. A central feature of LAMS is the visual authoring environment, where educators use a drag-and-drop environment to create sequences of learning activities. The visualisation is based on boxes…

Improving Collaborative Learning in the Classroom: Text Mining Based Grouping and Representing

ERIC Educational Resources Information Center

Erkens, Melanie; Bodemer, Daniel; Hoppe, H. Ulrich

2016-01-01

Orchestrating collaborative learning in the classroom involves tasks such as forming learning groups with heterogeneous knowledge and making learners aware of the knowledge differences. However, gathering information on which the formation of appropriate groups and the creation of graphical knowledge representations can be based is very effortful…

Online Resource-Based Learning Environment: Case Studies in Primary Classrooms

ERIC Educational Resources Information Center

So, Winnie Wing Mui; Ching, Fiona Ngai Ying

2012-01-01

This paper discusses the creation of learning environments with online resources by three primary school teachers for pupil's learning of science-related topics with reference to the resource-based e-learning environments (RBeLEs) framework. Teachers' choice of contexts, resources, tools, and scaffolds in designing the learning environments are…

Web-Based Instruction (WBI): An Introduction.

ERIC Educational Resources Information Center

Khan, Badrul H.

1998-01-01

Advances in information technology, coupled with changes in society, are creating new paradigms for education. The Web, as a medium of learning and instruction, has the potential to support the creation of well-designed resources. A table of features and components associated with Web-based instruction learning environments is provided.…

Creating an X Window Terminal-Based Information Technology Center.

ERIC Educational Resources Information Center

Klassen, Tim W.

1997-01-01

The creation of an information technology center at the University of Oregon Science Library is described. Goals included providing access to Internet-based resources and multimedia software, platforms for running science-oriented software, and resources so students can create multimedia materials. A mixed-lab platform was created with Unix-based…

Cancer Care Initiative: Creation of a Comprehensive Cancer Center at Naval Medical Center Dan Diego

DTIC Science & Technology

2008-06-24

to know about and practice evidence - based medicine and are more experienced with many of the complexities related to difficult chronic illnesses...frequent requesters of evidence - based medicine . Clinical information systems are important to the model to help ensure productive interactions. An

Putting Life into Computer-Based Training: The Creation of an Epidemiologic Case Study.

ERIC Educational Resources Information Center

Gathany, Nancy C.; Stehr-Green, Jeanette K.

1994-01-01

Describes the design of "Pharyngitis in Louisiana," a computer-based epidemiologic case study that was created to teach students how to conduct disease outbreak investigations. Topics discussed include realistic content portrayals; graphics; interactive teaching methods; interaction between the instructional designer and the medical…

Scalable focused ion beam creation of nearly lifetime-limited single quantum emitters in diamond nanostructures

PubMed Central

Schröder, Tim; Trusheim, Matthew E.; Walsh, Michael; Li, Luozhou; Zheng, Jiabao; Schukraft, Marco; Sipahigil, Alp; Evans, Ruffin E.; Sukachev, Denis D.; Nguyen, Christian T.; Pacheco, Jose L.; Camacho, Ryan M.; Bielejec, Edward S.; Lukin, Mikhail D.; Englund, Dirk

2017-01-01

The controlled creation of defect centre—nanocavity systems is one of the outstanding challenges for efficiently interfacing spin quantum memories with photons for photon-based entanglement operations in a quantum network. Here we demonstrate direct, maskless creation of atom-like single silicon vacancy (SiV) centres in diamond nanostructures via focused ion beam implantation with ∼32 nm lateral precision and <50 nm positioning accuracy relative to a nanocavity. We determine the Si+ ion to SiV centre conversion yield to be ∼2.5% and observe a 10-fold conversion yield increase by additional electron irradiation. Low-temperature spectroscopy reveals inhomogeneously broadened ensemble emission linewidths of ∼51 GHz and close to lifetime-limited single-emitter transition linewidths down to 126±13 MHz corresponding to ∼1.4 times the natural linewidth. This method for the targeted generation of nearly transform-limited quantum emitters should facilitate the development of scalable solid-state quantum information processors. PMID:28548097

Scalable focused ion beam creation of nearly lifetime-limited single quantum emitters in diamond nanostructures

DOE PAGES

Schroder, Tim; Trusheim, Matthew E.; Walsh, Michael; ...

2017-05-26

The controlled creation of defect centre—nanocavity systems is one of the outstanding challenges for efficiently interfacing spin quantum memories with photons for photon-based entanglement operations in a quantum network. Here we demonstrate direct, maskless creation of atom-like single silicon vacancy (SiV) centres in diamond nanostructures via focused ion beam implantation with ~32 nm lateral precision and <50 nm positioning accuracy relative to a nanocavity. We determine the Si+ ion to SiV centre conversion yield to be ~2.5% and observe a 10-fold conversion yield increase by additional electron irradiation. Low-temperature spectroscopy reveals inhomogeneously broadened ensemble emission linewidths of ~51 GHz andmore » close to lifetime-limited single-emitter transition linewidths down to 126±13 MHz corresponding to ~1.4 times the natural linewidth. Furthermore, this method for the targeted generation of nearly transform-limited quantum emitters should facilitate the development of scalable solid-state quantum information processors.« less

Scalable focused ion beam creation of nearly lifetime-limited single quantum emitters in diamond nanostructures

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schroder, Tim; Trusheim, Matthew E.; Walsh, Michael

The controlled creation of defect centre—nanocavity systems is one of the outstanding challenges for efficiently interfacing spin quantum memories with photons for photon-based entanglement operations in a quantum network. Here we demonstrate direct, maskless creation of atom-like single silicon vacancy (SiV) centres in diamond nanostructures via focused ion beam implantation with ~32 nm lateral precision and <50 nm positioning accuracy relative to a nanocavity. We determine the Si+ ion to SiV centre conversion yield to be ~2.5% and observe a 10-fold conversion yield increase by additional electron irradiation. Low-temperature spectroscopy reveals inhomogeneously broadened ensemble emission linewidths of ~51 GHz andmore » close to lifetime-limited single-emitter transition linewidths down to 126±13 MHz corresponding to ~1.4 times the natural linewidth. Furthermore, this method for the targeted generation of nearly transform-limited quantum emitters should facilitate the development of scalable solid-state quantum information processors.« less

Nurturing gerontology students' intrinsic motivation to cocreate: The design of a powerful learning environment.

PubMed

Jukema, Jan S; Veerman, Mieke; Van Alphen, Jacqueline; Visser, Geraldine; Smits, Carolien; Kingma, Tineke

2017-09-21

Professionals such as gerontologists play an important role in the design, development and implementation of age-friendly services. and products, by using working methods and principles of co-creation. A Dutch undergraduate applied gerontology programme aims to train students in the why, how and what of co-creation. The degree to which students are intrinsically motivated to develop competencies depends on how their psychological needs are met. These needs are autonomy, an awareness of competence and a sense of relatedness, as described in the self-determination theory. To nurture the intrinsic motivation of the applied gerontology students, a realistic, powerful learning environment called the Living Lab Applied Gerontology was designed and implemented. The aim of this paper is to present the design of this powerful learning environment and to discuss its value for nurturing the students' intrinsic motivation for co-creation. Based on a focus group with eight students, we identify directions for further research and development of living labs.