Construction Equipment

NASA Astrophysics Data System (ADS)

1983-01-01

FMC Corporation conducts extensive proof lift tests and computerized analysis to insure that the cranes can lift rated capacity loads up to one million pounds in a wide range of applications. In their analysis work, engineers makes use of a computer program supplied by COSMIC. Called Analysis of Beam Columns, the program is used as part of the required analysis for determining bending moments, deflections and critical load for latticed crane booms.

Evaluation of implants coated with rhBMP-2 using two different coating strategies: a critical-size supraalveolar peri-implant defect study in dogs.

PubMed

Lee, Jaebum; Decker, John F; Polimeni, Giuseppe; Cortella, Carlo Alberto; Rohrer, Michael D; Wozney, John M; Hall, Jan; Susin, Cristiano; Wikesjö, Ulf M E

2010-06-01

Implants coated with recombinant human bone morphogenetic protein-2 (rhBMP-2) induce relevant bone formation but also resident bone remodelling. To compare the effect of implants fully or partially coated with rhBMP-2 on new bone formation and resident bone remodelling. Twelve, male, adult, Hound Labrador mongrel dogs were used. Critical-size, supraalveolar, peri-implant defects received titanium porous oxide surface implants coated in their most coronal aspect with rhBMP-2 (coronal-load/six animals) or by immersion of the entire implant in an rhBMP-2 solution (soak-load/six animals) for a total of 30 mug rhBMP-2/implant. All implants were air-dried. The animals were euthanized at 8 weeks for histometric evaluation. Clinical healing was uneventful. Supraalveolar bone formation was not significantly affected by the rhBMP-2 application protocol. New bone height and area averaged (+/- SE) 3.4 +/- 0.2 versus 3.5 +/- 0.4 mm and 2.6 +/- 0.4 versus 2.5 +/- 0.7 mm(2) for coronal-load and soak-load implants, respectively (p>0.05). The corresponding bone density and bone-implant contact (BIC) recordings averaged 38.0 +/- 3.8%versus 34.4 +/- 5.6% and 25.0 +/- 3.8%versus 31.2 +/- 3.3% (p>0.05). In contrast, resident bone remodelling was significantly influenced by the rhBMP-2 application protocol. Bone density outside the implants threads averaged 74.7 +/- 3.8% and 50.8 +/- 4.1% for coronal-load and soak-load implants, respectively (p<0.05); bone density within the thread area averaged 51.8 +/- 1.2% and 37.8 +/- 2.9%, and BIC 70.1 +/- 6.7% and 43.3 +/- 3.9% (p<0.05). Local application of rhBMP-2 appears to be a viable technology to support local bone formation and osseointegration. Coronal-load implants obviate resident bone remodelling without compromising new bone formation.

Applications of MICP source for next-generation photomask process

NASA Astrophysics Data System (ADS)

Kwon, Hyuk-Joo; Chang, Byung-Soo; Choi, Boo-Yeon; Park, Kyung H.; Jeong, Soo-Hong

2000-07-01

As critical dimensions of photomask extends into submicron range, critical dimension uniformity, edge roughness, macro loading effect, and pattern slope become tighter than before. Fabrication of photomask relies on the ability to pattern features with anisotropic profile. To improve critical dimension uniformity, dry etcher is one of the solution and inductively coupled plasma (ICP) sources have become one of promising high density plasma sources for dry etcher. In this paper, we have utilized dry etcher system with multi-pole ICP source for Cr etch and MoSi etch and have investigated critical dimension uniformity, slope, and defects. We will present dry etch process data by process optimization of newly designed dry etcher system. The designed pattern area is 132 by 132 mm2 with 23 by 23 matrix test patterns. 3 (sigma) of critical dimension uniformity is below 12 nm at 0.8 - 3.0 micrometers . In most cases, we can obtain zero defect masks which is operated by face- down loading.

Solutions for Critical Raw Materials under Extreme Conditions: A Review

PubMed Central

Grilli, Maria Luisa; Bellezze, Tiziano; Gamsjäger, Ernst; Rinaldi, Antonio; Novak, Pavel; Balos, Sebastian; Piticescu, Radu Robert; Ruello, Maria Letizia

2017-01-01

In Europe, many technologies with high socio-economic benefits face materials requirements that are often affected by demand-supply disruption. This paper offers an overview of critical raw materials in high value alloys and metal-matrix composites used in critical applications, such as energy, transportation and machinery manufacturing associated with extreme working conditions in terms of temperature, loading, friction, wear and corrosion. The goal is to provide perspectives about the reduction and/or substitution of selected critical raw materials: Co, W, Cr, Nb and Mg. PMID:28772645

A Relationship Between Constraint and the Critical Crack Tip Opening Angle

NASA Technical Reports Server (NTRS)

Johnston, William M.; James, Mark A.

2009-01-01

Of the various approaches used to model and predict fracture, the Crack Tip Opening Angle (CTOA) fracture criterion has been successfully used for a wide range of two-dimensional thin-sheet and thin plate applications. As thicker structure is considered, modeling the full three-dimensional fracture process will become essential. This paper investigates relationships between the local CTOA evaluated along a three-dimensional crack front and the corresponding local constraint. Previously reported tunneling crack front shapes were measured during fracture by pausing each test and fatigue cycling the specimens to mark the crack surface. Finite element analyses were run to model the tunneling shape during fracture, with the analysis loading conditions duplicating those tests. The results show an inverse relationship between the critical fracture value and constraint which is valid both before maximum load and after maximum load.

Quantification of baseline pupillary response and task-evoked pupillary response during constant and incremental task load.

PubMed

Mosaly, Prithima R; Mazur, Lukasz M; Marks, Lawrence B

2017-10-01

The methods employed to quantify the baseline pupil size and task-evoked pupillary response (TEPR) may affect the overall study results. To test this hypothesis, the objective of this study was to assess variability in baseline pupil size and TEPR during two basic working memory tasks: constant load of 3-letters memorisation-recall (10 trials), and incremental load memorisation-recall (two trials of each load level), using two commonly used methods (1) change from trail/load specific baseline, (2) change from constant baseline. Results indicated that there was a significant shift in baseline between the trails for constant load, and between the load levels for incremental load. The TEPR was independent of shifts in baseline using method 1 only for constant load, and method 2 only for higher levels of incremental load condition. These important findings suggest that the assessment of both the baseline and methods to quantify TEPR are critical in ergonomics application, especially in studies with small number of trials per subject per condition. Practitioner Summary: Quantification of TEPR can be affected by shifts in baseline pupil size that are most likely affected by non-cognitive factors when other external factors are kept constant. Therefore, quantification methods employed to compute both baseline and TEPR are critical in understanding the information processing of humans in practical ergonomics settings.

1.5 MW RF Load for ITER

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ives, Robert Lawrence; Marsden, David; Collins, George

Calabazas Creek Research, Inc. developed a 1.5 MW RF load for the ITER fusion research facility currently under construction in France. This program leveraged technology developed in two previous SBIR programs that successfully developed high power RF loads for fusion research applications. This program specifically focused on modifications required by revised technical performance, materials, and assembly specification for ITER. This program implemented an innovative approach to actively distribute the RF power inside the load to avoid excessive heating or arcing associated with constructive interference. The new design implemented materials and assembly changes required to meet specifications. Critical components were builtmore » and successfully tested during the program.« less

Dynamic Loading of Substation Distribution Transformers: An Application for use in a Production Grade Environment

NASA Astrophysics Data System (ADS)

Zhang, Ming

Recent trends in the electric power industry have led to more attention to optimal operation of power transformers. In a deregulated environment, optimal operation means minimizing the maintenance and extending the life of this critical and costly equipment for the purpose of maximizing profits. Optimal utilization of a transformer can be achieved through the use of dynamic loading. A benefit of dynamic loading is that it allows better utilization of the transformer capacity, thus increasing the flexibility and reliability of the power system. This document presents the progress on a software application which can estimate the maximum time-varying loading capability of transformers. This information can be used to load devices closer to their limits without exceeding the manufacturer specified operating limits. The maximally efficient dynamic loading of transformers requires a model that can accurately predict both top-oil temperatures (TOTs) and hottest-spot temperatures (HSTs). In the previous work, two kinds of thermal TOT and HST models have been studied and used in the application: the IEEE TOT/HST models and the ASU TOT/HST models. And, several metrics have been applied to evaluate the model acceptability and determine the most appropriate models for using in the dynamic loading calculations. In this work, an investigation to improve the existing transformer thermal models performance is presented. Some factors that may affect the model performance such as improper fan status and the error caused by the poor performance of IEEE models are discussed. Additional methods to determine the reliability of transformer thermal models using metrics such as time constant and the model parameters are also provided. A new production grade application for real-time dynamic loading operating purpose is introduced. This application is developed by using an existing planning application, TTeMP, as a start point, which is designed for the dispatchers and load specialists. To overcome the limitations of TTeMP, the new application can perform dynamic loading under emergency conditions, such as loss-of transformer loading. It also has the capability to determine the emergency rating of the transformers for a real-time estimation.

Operational experience and performance characteristics of a valve-regulated lead-acid battery energy-storage system for providing the customer with critical load protection and energy-management benefits at a lead-recycling plant

NASA Astrophysics Data System (ADS)

Hunt, G. W.

The Power Control Division of GNB Technologies, commissioned on May 13, 1996 a new facility which houses a 5-MW battery energy-storage system (BESS) at GNB's Lead Recycling Centre in Vernon, CA. When the plant loses utility power (which typically happens two or three times a year), the BESS will provide up to 5 MW of power at 4160 VAC in support of all the plant loads. Since the critical loads are not isolated, it is necessary to carry the entire plant load (maximum of 5 MVA) for a short period immediately following an incident until non-critical loads have been automatically shed. Plant loading typically peaks at 3.5 MVA with critical loads of about 2.1 MVA. The BESS also provides the manufacturing plant with customer-side-of-the-meter energy management options to reduce its energy demand during peak periods of the day. The BESS has provided a reduction in monthly electric bills through daily peak-shaving. By design, the battery can provide up to 2.5 MWh of energy and still retain 2.5 MWh of capacity in reserve to handle the possibility of a power outage in protecting the critical loads for up to 1 h. By storing energy from the utility during off-peak hours of the night in the batteries when the cost is low (US4.5¢ per kWh), GNB can then discharge this energy during high demand periods of the day (US14.50 per kW). For example, by reducing its peak demand by 300 kW, the lead-recycling centre can save over US4000 per month in its electric bills. The BESS at Vernon represents a first large-scale use of valve-regulated lead-acid batteries in such a demanding application. This paper presents a summary of the operational experience and performance characteristics of the BESS over the past 2 years.

A preliminary psychometric evaluation of the eight-item cognitive load scale.

PubMed

Pignatiello, Grant A; Tsivitse, Emily; Hickman, Ronald L

2018-04-01

The aim of this article is to report the psychometric properties of the eight-item cognitive load scale. According to cognitive load theory, the formatting and delivery of healthcare education influences the degree to which patients and/or family members can engage their working memory systems for learning. However, despite its relevance, cognitive load has not yet been evaluated among surrogate decision makers exposed to electronic decision support for healthcare decisions. To date, no psychometric analyses of instruments evaluating cognitive load have been reported within healthcare settings. A convenience sample of 62 surrogate decision makers for critically ill patients were exposed to one of two healthcare decision support interventions were recruited from four intensive care units at a tertiary medical center in Northeast Ohio. Participants were administered a battery of psychosocial instruments and the eight-item cognitive load scale (CLS). The CLS demonstrated a bidimensional factor structure with acceptable discriminant validity and internal consistency reliability (Cronbach's α = 0.75 and 0.89). The CLS is a psychometrically sound instrument that may be used in the evaluation of decision support among surrogate decision makers of the critically ill. The authors recommend application of the cognitive load scale in the evaluation and development of healthcare education and interventions. Copyright © 2018 Elsevier Inc. All rights reserved.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kilpi, Lauri, E-mail: Lauri.Kilpi@vtt.fi; Ylivaara, Oili M. E.; Vaajoki, Antti

The scratch test method is widely used for adhesion evaluation of thin films and coatings. Usual critical load criteria designed for scratch testing of coatings were not applicable to thin atomic layer deposition (ALD) films on silicon wafers. Thus, the bases for critical load evaluation were established and the critical loads suitable for ALD coating adhesion evaluation on silicon wafers were determined in this paper as L{sub CSi1}, L{sub CSi2}, L{sub CALD1}, and L{sub CALD2}, representing the failure points of the silicon substrate and the coating delamination points of the ALD coating. The adhesion performance of the ALD Al{sub 2}O{submore » 3}, TiO{sub 2}, TiN, and TaCN+Ru coatings with a thickness range between 20 and 600 nm and deposition temperature between 30 and 410 °C on silicon wafers was investigated. In addition, the impact of the annealing process after deposition on adhesion was evaluated for selected cases. The tests carried out using scratch and Scotch tape test showed that the coating deposition and annealing temperature, thickness of the coating, and surface pretreatments of the Si wafer had an impact on the adhesion performance of the ALD coatings on the silicon wafer. There was also an improved load carrying capacity due to Al{sub 2}O{sub 3}, the magnitude of which depended on the coating thickness and the deposition temperature. The tape tests were carried out for selected coatings as a comparison. The results show that the scratch test is a useful and applicable tool for adhesion evaluation of ALD coatings, even when carried out for thin (20 nm thick) coatings.« less

Stress Analysis of B-52B and B-52H Air-Launching Systems Failure-Critical Structural Components

NASA Technical Reports Server (NTRS)

Ko, William L.

2005-01-01

The operational life analysis of any airborne failure-critical structural component requires the stress-load equation, which relates the applied load to the maximum tangential tensile stress at the critical stress point. The failure-critical structural components identified are the B-52B Pegasus pylon adapter shackles, B-52B Pegasus pylon hooks, B-52H airplane pylon hooks, B-52H airplane front fittings, B-52H airplane rear pylon fitting, and the B-52H airplane pylon lower sway brace. Finite-element stress analysis was performed on the said structural components, and the critical stress point was located and the stress-load equation was established for each failure-critical structural component. The ultimate load, yield load, and proof load needed for operational life analysis were established for each failure-critical structural component.

A New Energy-Critical Plane Damage Parameter for Multiaxial Fatigue Life Prediction of Turbine Blades.

PubMed

Yu, Zheng-Yong; Zhu, Shun-Peng; Liu, Qiang; Liu, Yunhan

2017-05-08

As one of fracture critical components of an aircraft engine, accurate life prediction of a turbine blade to disk attachment is significant for ensuring the engine structural integrity and reliability. Fatigue failure of a turbine blade is often caused under multiaxial cyclic loadings at high temperatures. In this paper, considering different failure types, a new energy-critical plane damage parameter is proposed for multiaxial fatigue life prediction, and no extra fitted material constants will be needed for practical applications. Moreover, three multiaxial models with maximum damage parameters on the critical plane are evaluated under tension-compression and tension-torsion loadings. Experimental data of GH4169 under proportional and non-proportional fatigue loadings and a case study of a turbine disk-blade contact system are introduced for model validation. Results show that model predictions by Wang-Brown (WB) and Fatemi-Socie (FS) models with maximum damage parameters are conservative and acceptable. For the turbine disk-blade contact system, both of the proposed damage parameters and Smith-Watson-Topper (SWT) model show reasonably acceptable correlations with its field number of flight cycles. However, life estimations of the turbine blade reveal that the definition of the maximum damage parameter is not reasonable for the WB model but effective for both the FS and SWT models.

A New Energy-Critical Plane Damage Parameter for Multiaxial Fatigue Life Prediction of Turbine Blades

PubMed Central

Yu, Zheng-Yong; Zhu, Shun-Peng; Liu, Qiang; Liu, Yunhan

2017-01-01

As one of fracture critical components of an aircraft engine, accurate life prediction of a turbine blade to disk attachment is significant for ensuring the engine structural integrity and reliability. Fatigue failure of a turbine blade is often caused under multiaxial cyclic loadings at high temperatures. In this paper, considering different failure types, a new energy-critical plane damage parameter is proposed for multiaxial fatigue life prediction, and no extra fitted material constants will be needed for practical applications. Moreover, three multiaxial models with maximum damage parameters on the critical plane are evaluated under tension-compression and tension-torsion loadings. Experimental data of GH4169 under proportional and non-proportional fatigue loadings and a case study of a turbine disk-blade contact system are introduced for model validation. Results show that model predictions by Wang-Brown (WB) and Fatemi-Socie (FS) models with maximum damage parameters are conservative and acceptable. For the turbine disk-blade contact system, both of the proposed damage parameters and Smith-Watson-Topper (SWT) model show reasonably acceptable correlations with its field number of flight cycles. However, life estimations of the turbine blade reveal that the definition of the maximum damage parameter is not reasonable for the WB model but effective for both the FS and SWT models. PMID:28772873

Evaluation of implants coated with recombinant human bone morphogenetic protein-2 and vacuum-dried using the critical-size supraalveolar peri-implant defect model in dogs.

PubMed

Decker, John F; Lee, Jaebum; Cortella, Carlo Alberto; Polimeni, Giuseppe; Rohrer, Michael D; Wozney, John M; Hall, Jan; Susin, Cristiano; Wikesjö, Ulf M E

2010-12-01

Endosseous implants coated with recombinant human bone morphogenetic protein-2 (rhBMP-2) in a laboratory bench setting and air-dried induce relevant bone formation but also resident bone remodeling. Thus, the objective of this study is to evaluate the effect of implants fully or partially coated with rhBMP-2 and vacuum-dried using an industrial process on local bone formation and resident bone remodeling. Twelve male adult Hound Labrador mongrel dogs were used. Critical-size, supraalveolar, peri-implant defects received titanium porous oxide surface implants coated in their most coronal aspect with rhBMP-2 (coronal-load, six animals), or by immersion of the entire implant in a rhBMP-2 solution (soak-load, six animals) for a total of 30 μg rhBMP-2 per implant. All implants were vacuum-dried. The animals were sacrificed at 8 weeks for histometric evaluation. Clinical healing was unremarkable. Bone formation was not significantly affected by the rhBMP-2 application protocol. New bone height and area averaged (± SE) 3.2 ± 0.5 versus 3.6 ± 0.3 mm, and 2.3 ± 0.5 versus 2.6 ± 0.8 mm(2) for coronal-load and soak-load implants, respectively (P >0.05). The corresponding bone density and bone-implant contact registrations averaged 46.7% ± 5.8% versus 31.6% ± 4.4%, and 28% ± 5.6% versus 36.9% ± 3.4% (P >0.05). In contrast, resident bone remodeling was significantly influenced by the rhBMP-2 application protocol. Peri-implant bone density averaged 72.2% ± 2.1% for coronal-load versus 60.6% ± 4.7% for soak-load implants (P <0.05); the corresponding bone-implant contact averaged 70.7% ± 6.1% versus 47.2% ± 6.0% (P <0.05). Local application of rhBMP-2 and vacuum-drying using industrial process seems to be a viable technology to manufacture implants that support local bone formation and osseointegration. Coronal-load implants obviate resident bone remodeling without compromising local bone formation.

A review of the calculation procedure for critical acid loads for terrestrial ecosystems.

PubMed

van der Salm, C; de Vries, W

2001-04-23

Target loads for acid deposition in the Netherlands, as formulated in the Dutch environmental policy plan, are based on critical load calculations at the end of the 1980s. Since then knowledge on the effect of acid deposition on terrestrial ecosystems has substantially increased. In the early 1990s a simple mass balance model was developed to calculate critical loads. This model was evaluated and the methods were adapted to represent the current knowledge. The main changes in the model are the use of actual empirical relationships between Al and H concentrations in the soil solution, the addition of a constant base saturation as a second criterion for soil quality and the use of tree species-dependant critical Al/base cation (BC) ratios for Dutch circumstances. The changes in the model parameterisation and in the Al/BC criteria led to considerably (50%) higher critical loads for root damage. The addition of a second criterion in the critical load calculations for soil quality caused a decrease in the critical loads for soils with a median to high base saturation such as loess and clay soils. The adaptation hardly effected the median critical load for soil quality in the Netherlands, since only 15% of the Dutch forests occur on these soils. On a regional scale, however, critical loads were (much) lower in areas where those soils are located.

Estimates of critical acid loads and exceedances for forest soils across the conterminous United States.

PubMed

McNulty, Steven G; Cohen, Erika C; Moore Myers, Jennifer A; Sullivan, Timothy J; Li, Harbin

2007-10-01

Concern regarding the impacts of continued nitrogen and sulfur deposition on ecosystem health has prompted the development of critical acid load assessments for forest soils. A critical acid load is a quantitative estimate of exposure to one or more pollutants at or above which harmful acidification-related effects on sensitive elements of the environment occur. A pollutant load in excess of a critical acid load is termed exceedance. This study combined a simple mass balance equation with national-scale databases to estimate critical acid load and exceedance for forest soils at a 1-km(2) spatial resolution across the conterminous US. This study estimated that about 15% of US forest soils are in exceedance of their critical acid load by more than 250eqha(-1)yr(-1), including much of New England and West Virginia. Very few areas of exceedance were predicted in the western US.

Effect of load eccentricity on the buckling of thin-walled laminated C-columns

NASA Astrophysics Data System (ADS)

Wysmulski, Pawel; Teter, Andrzej; Debski, Hubert

2018-01-01

The study investigates the behaviour of short, thin-walled laminated C-columns under eccentric compression. The tested columns are simple-supported. The effect of load inaccuracy on the critical and post-critical (local buckling) states is examined. A numerical analysis by the finite element method and experimental tests on a test stand are performed. The samples were produced from a carbon-epoxy prepreg by the autoclave technique. The experimental tests rest on the assumption that compressive loads are 1.5 higher than the theoretical critical force. Numerical modelling is performed using the commercial software package ABAQUS®. The critical load is determined by solving an eigen problem using the Subspace algorithm. The experimental critical loads are determined based on post-buckling paths. The numerical and experimental results show high agreement, thus demonstrating a significant effect of load inaccuracy on the critical load corresponding to the column's local buckling.

Generating Performance Models for Irregular Applications

DOE Office of Scientific and Technical Information (OSTI.GOV)

Friese, Ryan D.; Tallent, Nathan R.; Vishnu, Abhinav

2017-05-30

Many applications have irregular behavior --- non-uniform input data, input-dependent solvers, irregular memory accesses, unbiased branches --- that cannot be captured using today's automated performance modeling techniques. We describe new hierarchical critical path analyses for the \\Palm model generation tool. To create a model's structure, we capture tasks along representative MPI critical paths. We create a histogram of critical tasks with parameterized task arguments and instance counts. To model each task, we identify hot instruction-level sub-paths and model each sub-path based on data flow, instruction scheduling, and data locality. We describe application models that generate accurate predictions for strong scalingmore » when varying CPU speed, cache speed, memory speed, and architecture. We present results for the Sweep3D neutron transport benchmark; Page Rank on multiple graphs; Support Vector Machine with pruning; and PFLOTRAN's reactive flow/transport solver with domain-induced load imbalance.« less

Climate change impacts on forest soil critical acid loads and exceedances at a national scale

Treesearch

Steven G. McNulty; Erika C. Cohen; Jennifer A. Moore Myers

2013-01-01

Federal agencies are currently developing guidelines for forest soil critical acid loads across the United States. A critical acid load is defined as the amount of acid deposition (usually expressed on an annual basis) that an ecosystem can absorb. Traditionally, an ecosystem is considered to be at risk for health impairment when the critical acid load exceeds a level...

[Mapping Critical Loads of Heavy Metals for Soil Based on Different Environmental Effects].

PubMed

Shi, Ya-xing; Wu, Shao-hua; Zhou, Sheng-lu; Wang, Chun-hui; Chen, Hao

2015-12-01

China's rapid development of industrialization and urbanization causes the growing problem of heavy metal pollution of soil, threatening environment and human health. Therefore, prevention and management of heavy metal pollution become particularly important. Critical loads of heavy metals are an important management tool that can be utilized to prevent the occurrence of heavy metal pollution. Our study was based on three cases: status balance, water environmental effects and health risks. We used the steady-state mass balance equation to calculate the critical loads of Cd, Cu, Pb, Zn at different effect levels and analyze the values and spatial variation of critical loads. In addition, we used the annual input fluxes of heavy metals of the agro-ecosystem in the Yangtze River delta and China to estimate the proportion of area with exceedance of critical loads. The results demonstrated that the critical load value of Cd was the minimum, and the values of Cu and Zn were lager. There were spatial differences among the critical loads of four elements in the study area, lower critical loads areas mainly occurred in woodland and high value areas distributed in the east and southwest of the study area, while median values and the medium high areas mainly occurred in farmland. Comparing the input fluxes of heavy metals, we found that Pb and Zn in more than 90% of the area exceeded the critical loads under different environmental effects in the study area. The critical load exceedance of Cd mainly occurred under the status balance and the water environmental effect, while Cu under the status balance and water environmental effect with a higher proportion of exceeded areas. Critical loads of heavy metals at different effect levels in this study could serve as a reference from effective control of the emissions of heavy metals and to prevent the occurrence of heavy metal pollution.

A Method for Computing Leading-Edge Loads

NASA Technical Reports Server (NTRS)

Rhode, Richard V; Pearson, Henry A

1933-01-01

In this report a formula is developed that enables the determination of the proper design load for the portion of the wing forward of the front spar. The formula is inherently rational in concept, as it takes into account the most important variables that affect the leading-edge load, although theoretical rigor has been sacrificed for simplicity and ease of application. Some empirical corrections, based on pressure distribution measurements on the PW-9 and M-3 airplanes have been introduced to provide properly for biplanes. Results from the formula check experimental values in a variety of cases with good accuracy in the critical loading conditions. The use of the method for design purposes is therefore felt to be justified and is recommended.

Using change-point models to estimate empirical critical loads for nitrogen in mountain ecosystems.

PubMed

Roth, Tobias; Kohli, Lukas; Rihm, Beat; Meier, Reto; Achermann, Beat

2017-01-01

To protect ecosystems and their services, the critical load concept has been implemented under the framework of the Convention on Long-range Transboundary Air Pollution (UNECE) to develop effects-oriented air pollution abatement strategies. Critical loads are thresholds below which damaging effects on sensitive habitats do not occur according to current knowledge. Here we use change-point models applied in a Bayesian context to overcome some of the difficulties when estimating empirical critical loads for nitrogen (N) from empirical data. We tested the method using simulated data with varying sample sizes, varying effects of confounding variables, and with varying negative effects of N deposition on species richness. The method was applied to the national-scale plant species richness data from mountain hay meadows and (sub)alpine scrubs sites in Switzerland. Seven confounding factors (elevation, inclination, precipitation, calcareous content, aspect as well as indicator values for humidity and light) were selected based on earlier studies examining numerous environmental factors to explain Swiss vascular plant diversity. The estimated critical load confirmed the existing empirical critical load of 5-15 kg N ha -1 yr -1 for (sub)alpine scrubs, while for mountain hay meadows the estimated critical load was at the lower end of the current empirical critical load range. Based on these results, we suggest to narrow down the critical load range for mountain hay meadows to 10-15 kg N ha -1 yr -1 . Copyright © 2016 Elsevier Ltd. All rights reserved.

Installation Torque Tables for Noncritical Applications

NASA Technical Reports Server (NTRS)

Rivera-Rosario, Hazel T.; Powell, Joseph S.

2017-01-01

The objective of this project is to define torque values for bolts and screws when loading is not a concern. Fasteners require a certain torque to fulfill its function and prevent failure. NASA Glenn Research Center did not have a set of fastener torque tables for non-critical applications without loads, usually referring to hand-tight or wrench-tight torqueing. The project is based on two formulas, torque and pullout load. Torque values are calculated giving way to preliminary data tables. Testing is done to various bolts and metal plates, torqueing them until the point of failure. Around 640 torque tables were developed for UNC, UNF, and M fasteners. Different lengths of thread engagement were analyzed for the 5 most common materials used at GRC. The tables were put together in an Excel spreadsheet and then formatted into a Word document. The plan is to later convert this to an official technical publication or memorandum.

Equivalent damage: A critical assessment

NASA Technical Reports Server (NTRS)

Laflen, J. R.; Cook, T. S.

1982-01-01

Concepts in equivalent damage were evaluated to determine their applicability to the life prediction of hot path components of aircraft gas turbine engines. Equivalent damage was defined as being those effects which influence the crack initiation life-time beyond the damage that is measured in uniaxial, fully-reversed sinusoidal and isothermal experiments at low homologous temperatures. Three areas of equivalent damage were examined: mean stress, cumulative damage, and multiaxiality. For each area, a literature survey was conducted to aid in selecting the most appropriate theories. Where possible, data correlations were also used in the evaluation process. A set of criteria was developed for ranking the theories in each equivalent damage regime. These criteria considered aspects of engine utilization as well as the theoretical basis and correlative ability of each theory. In addition, consideration was given to the complex nature of the loading cycle at fatigue critical locations of hot path components; this loading includes non-proportional multiaxial stressing, combined temperature and strain fluctuations, and general creep-fatigue interactions. Through applications of selected equivalent damage theories to some suitable data sets it was found that there is insufficient data to allow specific recommendations of preferred theories for general applications. A series of experiments and areas of further investigations were identified.

Resonant UPS topologies for the emerging hybrid fiber-coaxial networks

NASA Astrophysics Data System (ADS)

Pinheiro, Humberto

Uninterruptible power supply (UPS) systems have been extensively applied to feed critical loads in many areas. Typical examples of critical loads include life-support equipment, computers and telecommunication systems. Although all UPS systems have a common purpose to provide continuous power-to critical loads, the emerging hybrid fiber-coaxial networks have created the need for specific types of UPS topologies. For example, galvanic isolation for the load and the battery, small size, high input power factor, and trapezoidal output voltage waveforms are among the required features of UPS topologies for hybrid fiber-coaxial networks. None of the conventional UPS topologies meet all these requirements. Consequently. this thesis is directed towards the design and analysis of UPS topologies for this new application. Novel UPS topologies are proposed and control techniques are developed to allow operation at high switching frequencies without penalizing the converter efficiency. By the use of resonant converters in the proposed UPS topologies. a high input power factor is achieved without requiring a dedicated power factor correction stage. In addition, a self-sustained oscillation control method is proposed to ensure soft switching under all operating conditions. A detailed analytical treatment of the resonant converters in the proposed UPS topologies is presented and design procedures illustrated. Simulation and experimental results are presented to validate the analyses and to demonstrate the feasibility of the proposed schemes.

Creep of Hi-Nicalon S Ceramic Fiber Tows at Elevated Temperature in Air and in Steam

DTIC Science & Technology

2012-03-22

temperature and environmental effects is a critical factor in development of composites with load carrying capacity and environmental durability...applications, including aircraft jet engines, gas turbines for electrical power/steam cogeneration , as well as nuclear power plant components. It is

Critical Branches and Lucky Loads in Control-Independence Architectures

ERIC Educational Resources Information Center

Malik, Kshitiz

2009-01-01

Branch mispredicts have a first-order impact on the performance of integer applications. Control Independence (CI) architectures aim to overlap the penalties of mispredicted branches with useful execution by spawning control-independent work as separate threads. Although control independent, such threads may consume register and memory values…

Synthesis and characterization of novel dual-responsive nanogels and their application as drug delivery systems

NASA Astrophysics Data System (ADS)

Peng, Jinrong; Qi, Tingting; Liao, Jinfeng; Fan, Min; Luo, Feng; Li, He; Qian, Zhiyong

2012-03-01

In this study, a temperature/pH dual-response nanogel based on NIPAm, MAA, and PEGMA was synthesized via emulsion polymerization and characterized by 1H-NMR, FT-IR, TEM and DLS. By introducing a novel initiator, through which PEG-AIBN-PEG was synthesized, it was revealed that the PEG segments from PEG-AIBN-PEG with a dosage of initiator had a significant influence over the macro-state and stability of the nanogels. In order to optimize the feeding prescription for better application as a drug delivery system, the effect of the co-monomer contents on the response to stimuli (temperature and pH value) and cytotoxicity of the nanogels has been studied in detail. The results demonstrated that the responsiveness, reversibility and volume phase transition critical value of the nanogels could be controlled by adjusting the feeding ratio of the co-monomers in the synthesis process. MTT assay results revealed that nanogels with appropriate compositions showed good biocompatibility and relatively low toxicity. Most importantly, by studying the drug loading behavior, it was found that the dimensions of the drug molecules had a considerable influence on the drug loading efficiency and loading capacity of the nanogels, and that the mechanism by which drug molecule sizes influence the drug loading behavior of nanogels needs further investigation. The results indicated that such PNMP nanogels might have potential applications in drug delivery and other medical applications, but that the drug loading mechanism must be further developed.

The Critical Compression Load for a Universal Testing Machine When the Specimen Is Loaded Through Knife Edges

NASA Technical Reports Server (NTRS)

Lundquist, Eugene E; Schwartz, Edward B

1942-01-01

The results of a theoretical and experimental investigation to determine the critical compression load for a universal testing machine are presented for specimens loaded through knife edges. The critical load for the testing machine is the load at which one of the loading heads becomes laterally instable in relation to the other. For very short specimens the critical load was found to be less than the rated capacity given by the manufacturer for the machine. A load-length diagram is proposed for defining the safe limits of the test region for the machine. Although this report is particularly concerned with a universal testing machine of a certain type, the basic theory which led to the derivation of the general equation for the critical load, P (sub cr) = alpha L can be applied to any testing machine operated in compression where the specimen is loaded through knife edges. In this equation, L is the length of the specimen between knife edges and alpha is the force necessary to displace the upper end of the specimen unit horizontal distance relative to the lower end of the specimen in a direction normal to the knife edges through which the specimen is loaded.

CRITICAL LOADS METHODS

EPA Science Inventory

I summarize the results of an interagency project that 1) defines a generic approach to quantifying and reporting critical loads, and 2) exercises that generic approach by examining a data rich system -- the critical loads of sulfur deposition and it's effect on the chronic acidi...

The Residual Strength of a Ship after an Internal Explosion

DTIC Science & Technology

1988-05-01

uafcd by the presence of small holes, and is roughly equal to three times the critical buckling load. With regards to application , however, the...not be described by a single measure of failure. Several promising approaches to EPFM are being developed, however, which offer some insights into the...toughness so determined is a material property, and indicates that the rigid-plastic equation is valid for certain applications . From a global energy

Investigation of the Fracture Behavior of Scaled HY-130 Weldments

DTIC Science & Technology

1990-06-01

RESULTS OF EPFM ANALYSIS OF TFREE-POINT BEND SPECIMENS OF DIFFERENT SIZES ........... D-48 xi NAVSWC TR 90-360 TABLES 1 RESULTS OF DYNAMIC FRACTURE...characterize the critical loading needed to cause fracture of the welded joint. An example of such a measure of severity applicable to structures with...weldments. Application of the approach to two titanium alloys and the results of that hwvestigation will be presented in another report. The next four

Consideration of critical axial properties of pristine and defected carbon nanotubes under compression.

PubMed

Ranjbartoreh, A R; Su, D; Wang, G

2012-06-01

Carbon nanotubes are hexagonally configured carbon atoms in cylindrical structures. Exceptionally high mechanical strength, electrical conductivity, surface area, thermal stability and optical transparency of carbon nanotubes outperformed other known materials in numerous advanced applications. However, their mechanical behaviors under practical loading conditions remain to be demonstrated. This study investigates the critical axial properties of pristine and defected single- and multi-walled carbon nanotubes under axial compression. Molecular dynamics simulation method has been employed to consider the destructive effects of Stone-Wales and atom vacancy defects on mechanical properties of armchair and zigzag carbon nanotubes under compressive loading condition. Armchair carbon nanotube shows higher axial stability than zigzag type. Increase in wall number leads to less susceptibility of multi-walled carbon nanotubes to defects and higher stability of them under axial compression. Atom vacancy defect reveals higher destructive effect than Stone-Wales defect on mechanical properties of carbon nanotubes. Critical axial strain of single-walled carbon nanotube declines by 67% and 26% due to atom vacancy and Stone-Wales defects.

Stress intensity factors and COD in an orthotropic strip

NASA Technical Reports Server (NTRS)

Kaya, A. C.; Erdogan, F.

1980-01-01

The elasticity problem for an orthotropic strip or a beam with an internal or an edge crack under general loading conditions is considered. The numerical results are given for four basic loading conditions, namely, uniform tension, pure bending, three point bending, and concentrated surface shear loading. For the strip with an edge crack additional results regarding the crack opening displacements are obtained by using the plastic strip model. A critical quantity which is tabulated is the maximum compressive stress in the plane of the crack. It is shown that this stress may easily exceed the yield limit in compression and hence may severely limit the range of application of the plasticity results.

Applications of the DOE/NASA wind turbine engineering information system

NASA Technical Reports Server (NTRS)

Neustadter, H. E.; Spera, D. A.

1981-01-01

A statistical analysis of data obtained from the Technology and Engineering Information Systems was made. The systems analyzed consist of the following elements: (1) sensors which measure critical parameters (e.g., wind speed and direction, output power, blade loads and component vibrations); (2) remote multiplexing units (RMUs) on each wind turbine which frequency-modulate, multiplex and transmit sensor outputs; (3) on-site instrumentation to record, process and display the sensor output; and (4) statistical analysis of data. Two examples of the capabilities of these systems are presented. The first illustrates the standardized format for application of statistical analysis to each directly measured parameter. The second shows the use of a model to estimate the variability of the rotor thrust loading, which is a derived parameter.

Recent developments on SMA actuators: predicting the actuation fatigue life for variable loading schemes

NASA Astrophysics Data System (ADS)

Wheeler, Robert W.; Lagoudas, Dimitris C.

2017-04-01

Shape memory alloys (SMAs), due to their ability to repeatably recover substantial deformations under applied mechanical loading, have the potential to impact the aerospace, automotive, biomedical, and energy industries as weight and volume saving replacements for conventional actuators. While numerous applications of SMA actuators have been flight tested and can be found in industrial applications, these actuators are generally limited to non-critical components, are not widely implemented and frequently one-off designs, and are generally overdesigned due to a lack of understanding of the effect of the loading path on the fatigue life and the lack of an accurate method for predicting actuator lifetimes. In recent years, multiple research efforts have increased our understanding of the actuation fatigue process of SMAs. These advances can be utilized to predict the fatigue lives and failure loads in SMA actuators. Additionally, these prediction methods can be implemented in order to intelligently design actuators in accordance with their fatigue and failure limits. In the following paper, both simple and complex thermomechanical loading paths have been considered. Experimental data was utilized from two material systems: equiatomic Nickel-Titanium and Nickelrich Nickel-Titanium.

Usefulness of Compile-Time Restructuring of LGDF Programs in Throughput- Critical Applications

DTIC Science & Technology

1993-09-01

efficiency of the sufers . Ma overhead can be reduced effecively by using the node and an: attributes of the data flow graph at ccunpie-time to...intolerable delays and insufficient buffer space, especiall underbhigh loads. A. THESIS SCOPE AND CONTRIB~tMON The focus of this work is on compile-time

Integration and consolidation of border freight transportation data for planning applications and characterization of NAFTA truck loads for aiding in transportation infrastructure management : second year.

DOT National Transportation Integrated Search

2008-07-01

Average Daily Truck Traffic (ADTT) increased dramatically in Texas in the 1990s partly because of the : implementation of the North American Free Trade Agreement (NAFTA). Accurate information on truck : volumes and truck characteristics is critical t...

A screening procedure to evaluate air pollution effects on Class I wilderness areas

Treesearch

Douglas G. Fox; Ann M. Bartuska; James G. Byrne; Ellis Cowling; Richard Fisher; Gene E. Likens; Steven E. Lindberg; Rick A. Linthurst; Jay Messer; Dale S. Nichols

1989-01-01

This screening procedure is intended to help wilderness managers conduct "adverse impact determinations" as part of Prevention of Significant Deterioration (PSD) applications for sources that emit air pollutants that might impact Class I wildernesses. The process provides an initial estimate of susceptibility to critical loadings for sulfur, nitrogen, and...

Real-time anomaly detection for very short-term load forecasting

DOE Office of Scientific and Technical Information (OSTI.GOV)

Luo, Jian; Hong, Tao; Yue, Meng

Although the recent load information is critical to very short-term load forecasting (VSTLF), power companies often have difficulties in collecting the most recent load values accurately and timely for VSTLF applications. This paper tackles the problem of real-time anomaly detection in most recent load information used by VSTLF. This paper proposes a model-based anomaly detection method that consists of two components, a dynamic regression model and an adaptive anomaly threshold. The case study is developed using the data from ISO New England. This paper demonstrates that the proposed method significantly outperforms three other anomaly detection methods including two methods commonlymore » used in the field and one state-of-the-art method used by a winning team of the Global Energy Forecasting Competition 2014. Lastly, a general anomaly detection framework is proposed for the future research.« less

Real-time anomaly detection for very short-term load forecasting

DOE PAGES

Luo, Jian; Hong, Tao; Yue, Meng

2018-01-06

Although the recent load information is critical to very short-term load forecasting (VSTLF), power companies often have difficulties in collecting the most recent load values accurately and timely for VSTLF applications. This paper tackles the problem of real-time anomaly detection in most recent load information used by VSTLF. This paper proposes a model-based anomaly detection method that consists of two components, a dynamic regression model and an adaptive anomaly threshold. The case study is developed using the data from ISO New England. This paper demonstrates that the proposed method significantly outperforms three other anomaly detection methods including two methods commonlymore » used in the field and one state-of-the-art method used by a winning team of the Global Energy Forecasting Competition 2014. Lastly, a general anomaly detection framework is proposed for the future research.« less

Constitutive modeling of the dynamic-tensile-extrusion test of PTFE

NASA Astrophysics Data System (ADS)

Resnyansky, A. D.; Brown, E. N.; Trujillo, C. P.; Gray, G. T.

2017-01-01

Use of polymers in defense, aerospace and industrial applications under extreme loading conditions makes prediction of the behavior of these materials very important. Crucial to this is knowledge of the physical damage response in association with phase transformations during loading and the ability to predict this via multi-phase simulation accounting for thermodynamical non-equilibrium and strain rate sensitivity. The current work analyzes Dynamic-Tensile-Extrusion (Dyn-Ten-Ext) experiments on polytetrafluoroethylene (PTFE). In particular, the phase transition during loading and subsequent tension are analyzed using a two-phase rate sensitive material model implemented in the CTH hydrocode. The calculations are compared with experimental high-speed photography. Deformation patterns and their link with changing loading modes are analyzed numerically and correlated to the test observations. It is concluded that the phase transformation is not as critical to the response of PTFE under Dyn-Ten-Ext loading as it is during the Taylor rod impact testing.

Quantitative correlation between the void morphology of niobium-tin wires and their irreversible critical current degradation upon mechanical loading

DOE PAGES

Barth, Christian; Seeber, B.; Rack, A.; ...

2018-04-26

Understanding the critical current performance variation of Nb 3Sn superconducting wires under mechanical loading is a crucial issue for the design of next generation accelerator and fusion magnets. In these applications, the mechanical properties of the conductors may become a limiting factor due to the strong electro-magnetic forces resulting from the combination of large magnets and intense magnetic fields. In particular, the presence of voids in the superconducting filament structure, which are formed during the fabrication and the reaction heat treatment, determines localized stress concentrations and possibly the formation of cracks. In this work, we demonstrate a quantitative correlation betweenmore » the void morphology and the electro-mechanical limits measured on different Bronze route Nb 3Sn wires. Hot Isostatic Pressing (HIP) prior to the reaction heat treatment is utilized to partially eliminate the voids. The wires’ void distributions - with and without HIP treatment - are detected and statistically analyzed using high energy X-ray micro tomography. The stress concentration due to the shape and distribution of the voids as well as their impact on the electro-mechanical properties are determined through finite element method modeling. Lastly, the results are quantitatively correlated with the experimentally determined limits of the irreversible critical current degradation upon mechanical loading.« less

Quantitative correlation between the void morphology of niobium-tin wires and their irreversible critical current degradation upon mechanical loading

DOE Office of Scientific and Technical Information (OSTI.GOV)

Barth, Christian; Seeber, B.; Rack, A.

Understanding the critical current performance variation of Nb 3Sn superconducting wires under mechanical loading is a crucial issue for the design of next generation accelerator and fusion magnets. In these applications, the mechanical properties of the conductors may become a limiting factor due to the strong electro-magnetic forces resulting from the combination of large magnets and intense magnetic fields. In particular, the presence of voids in the superconducting filament structure, which are formed during the fabrication and the reaction heat treatment, determines localized stress concentrations and possibly the formation of cracks. In this work, we demonstrate a quantitative correlation betweenmore » the void morphology and the electro-mechanical limits measured on different Bronze route Nb 3Sn wires. Hot Isostatic Pressing (HIP) prior to the reaction heat treatment is utilized to partially eliminate the voids. The wires’ void distributions - with and without HIP treatment - are detected and statistically analyzed using high energy X-ray micro tomography. The stress concentration due to the shape and distribution of the voids as well as their impact on the electro-mechanical properties are determined through finite element method modeling. Lastly, the results are quantitatively correlated with the experimentally determined limits of the irreversible critical current degradation upon mechanical loading.« less

Quantitative correlation between the void morphology of niobium-tin wires and their irreversible critical current degradation upon mechanical loading.

PubMed

Barth, C; Seeber, B; Rack, A; Calzolaio, C; Zhai, Y; Matera, D; Senatore, C

2018-04-26

Understanding the critical current performance variation of Nb 3 Sn superconducting wires under mechanical loading is a crucial issue for the design of next generation accelerator and fusion magnets. In these applications, the mechanical properties of the conductors may become a limiting factor due to the strong electro-magnetic forces resulting from the combination of large magnets and intense magnetic fields. In particular, the presence of voids in the superconducting filament structure, which are formed during the fabrication and the reaction heat treatment, determines localized stress concentrations and possibly the formation of cracks. In this work, we demonstrate a quantitative correlation between the void morphology and the electro-mechanical limits measured on different Bronze route Nb 3 Sn wires. Hot Isostatic Pressing (HIP) prior to the reaction heat treatment is utilized to partially eliminate the voids. The wires' void distributions - with and without HIP treatment - are detected and statistically analyzed using high energy X-ray micro tomography. The stress concentration due to the shape and distribution of the voids as well as their impact on the electro-mechanical properties are determined through finite element method modeling. Finally, the results are quantitatively correlated with the experimentally determined limits of the irreversible critical current degradation upon mechanical loading.

Vibration Testing of Electrical Cables to Quantify Loads at Tie-Down Locations

NASA Technical Reports Server (NTRS)

Dutson, Joseph D.

2013-01-01

The standard method for defining static equivalent structural load factors for components is based on Mile s equation. Unless test data is available, 5% critical damping is assumed for all components when calculating loads. Application of this method to electrical cable tie-down hardware often results in high loads, which often exceed the capability of typical tie-down options such as cable ties and P-clamps. Random vibration testing of electrical cables was used to better understand the factors that influence component loads: natural frequency, damping, and mass participation. An initial round of vibration testing successfully identified variables of interest, checked out the test fixture and instrumentation, and provided justification for removing some conservatism in the standard method. Additional testing is planned that will include a larger range of cable sizes for the most significant contributors to load as variables to further refine loads at cable tie-down points. Completed testing has provided justification to reduce loads at cable tie-downs by 45% with additional refinement based on measured cable natural frequencies.

Microgrids for Service Restoration to Critical Load in a Resilient Distribution System

DOE Office of Scientific and Technical Information (OSTI.GOV)

Xu, Yin; Liu, Chen-Ching; Schneider, Kevin P.

icrogrids can act as emergency sources to serve critical loads when utility power is unavailable. This paper proposes a resiliency-based methodology that uses microgrids to restore critical loads on distribution feeders after a major disaster. Due to limited capacity of distributed generators (DGs) within microgrids, dynamic performance of the DGs during the restoration process becomes essential. In this paper, the stability of microgrids, limits on frequency deviation, and limits on transient voltage and current of DGs are incorporated as constraints of the critical load restoration problem. The limits on the amount of generation resources within microgrids are also considered. Bymore » introducing the concepts of restoration tree and load group, restoration of critical loads is transformed into a maximum coverage problem, which is a linear integer program (LIP). The restoration paths and actions are determined for critical loads by solving the LIP. A 4-feeder, 1069-bus unbalanced test system with four microgrids is utilized to demonstrate the effectiveness of the proposed method. The method is applied to the distribution system in Pullman, WA, resulting in a strategy that uses generators on the Washington State University campus to restore service to the Hospital and City Hall in Pullman.« less

Mapping Critical Loads of Atmospheric Nitrogen Deposition in the Rocky Mountains, USA

NASA Astrophysics Data System (ADS)

Nanus, L.; Clow, D. W.; Stephens, V. C.; Saros, J. E.

2010-12-01

Atmospheric nitrogen (N) deposition can adversely affect sensitive aquatic ecosystems at high-elevations in the western United States. Critical loads are the amount of deposition of a given pollutant that an ecosystem can receive below which ecological effects are thought not to occur. GIS-based landscape models were used to create maps for high-elevation areas across the Rocky Mountain region showing current atmospheric deposition rates of nitrogen (N), critical loads of N, and exceedances of critical loads of N. Atmospheric N deposition maps for the region were developed at 400 meter resolution using gridded precipitation data and spatially interpolated chemical concentrations in rain and snow. Critical loads maps were developed based on chemical thresholds corresponding to observed ecological effects, and estimated ecosystem sensitivities calculated from basin characteristics. Diatom species assemblages were used as an indicator of ecosystem health to establish critical loads of N. Chemical thresholds (concentrations) were identified for surface waters by using a combination of in-situ growth experiments and observed spatial patterns in surface-water chemistry and diatom species assemblages across an N deposition gradient. Ecosystem sensitivity was estimated using a multiple-linear regression approach in which observed surface water nitrate concentrations at 530 sites were regressed against estimates of inorganic N deposition and basin characteristics (topography, soil type and amount, bedrock geology, vegetation type) to develop predictive models of surface water chemistry. Modeling results indicated that the significant explanatory variables included percent slope, soil permeability, and vegetation type (including barren land, shrub, and grassland) and were used to predict high-elevation surface water nitrate concentrations across the Rocky Mountains. Chemical threshold concentrations were substituted into an inverted form of the model equations and applied to estimate critical loads for each stream reach within a basin, from which critical loads maps were created. Atmospheric N deposition maps were overlaid on the critical loads maps to identify areas in the Rocky Mountain region where critical loads are being exceeded, or where they may do so in the future. This approach may be transferable to other high-elevation areas of the United States and the world.

Intraosseous heat generation during sonic, ultrasonic and conventional osteotomy.

PubMed

Rashad, Ashkan; Sadr-Eshkevari, Pooyan; Heiland, Max; Smeets, Ralf; Hanken, Henning; Gröbe, Alexander; Assaf, Alexandre T; Köhnke, Robert H; Mehryar, Pouyan; Riecke, Björn; Wikner, Johannes

2015-09-01

To assess heat generation in osteotomies during application of sonic and ultrasonic saws compared to conventional bur. Two glass-fiber isolated nickel-chromium thermocouples, connected to a recording device, were inserted into fresh bovine rib bone blocks and kept in 20 ± 0.5 °C water at determined depths of 1.5 mm (cortical layer) and 7 mm (cancellous layer) and 1.0 mm away from the planned osteotomy site. Handpieces, angulated 24-32°, were mounted in a vertical drill stand, and standardized weights were attached to their tops to exert loads of 5, 8, 15 and 20 N. Irrigation volumes of 20, 50 and 80 ml/min were used for each load. Ten repetitions were conducted using new tips each time for each test condition. The Mann-Whitney-U test was used for statistical analysis (p < 0.05). Both ultrasonic and sonic osteotomies were associated with significantly lower heat generation than conventional osteotomy (p < 0.01). Sonic osteotomy showed non-significantly lower heat generation than ultrasonic osteotomy. Generated heat never exceeded the critical limit of 47 °C in any system. Variation of load had no effect on heat generation in both bone layers for all tested systems. An increased irrigation volume resulted in lower temperatures in both cortical and cancellous bone layers during all tested osteotomies. Although none of the systems under the conditions of the present study resulted in critical heat generation, the application of ultrasonic and sonic osteotomy systems was associated with lower heat generation compared to the conventional saw osteotomy. Copious irrigation seems to play a critical role in preventing heat generation in the osteotomy site. Copyright © 2015 European Association for Cranio-Maxillo-Facial Surgery. Published by Elsevier Ltd. All rights reserved.

Empirical Critical Loads of Atmospheric Nitrogen Deposition for Nutrient Enrichment and Acidification of Sensitive US Lakes

EPA Science Inventory

A critical load is a “quantitative estimate of the exposure to one or more pollutants below which significant harmful effects on specified sensitive elements of the environment do not occur according to present knowledge”. Critical loads can be either modeled, or calculated empi...

Sintered Cathodes for All-Solid-State Structural Lithium-Ion Batteries

NASA Technical Reports Server (NTRS)

Huddleston, William; Dynys, Frederick; Sehirlioglu, Alp

2017-01-01

All-solid-state structural lithium ion batteries serve as both structural load-bearing components and as electrical energy storage devices to achieve system level weight savings in aerospace and other transportation applications. This multifunctional design goal is critical for the realization of next generation hybrid or all-electric propulsion systems. Additionally, transitioning to solid state technology improves upon battery safety from previous volatile architectures. This research established baseline solid state processing conditions and performance benchmarks for intercalation-type layered oxide materials for multifunctional application. Under consideration were lithium cobalt oxide and lithium nickel manganese cobalt oxide. Pertinent characteristics such as electrical conductivity, strength, chemical stability, and microstructure were characterized for future application in all-solid-state structural battery cathodes. The study includes characterization by XRD, ICP, SEM, ring-on-ring mechanical testing, and electrical impedance spectroscopy to elucidate optimal processing parameters, material characteristics, and multifunctional performance benchmarks. These findings provide initial conditions for implementing existing cathode materials in load bearing applications.

Marine west coast forests: Chapter 9

USGS Publications Warehouse

Perakis, Steven S.; Geiser, Linda H.; Lilleskov, Erik A.; Pardo, Linda H.; Robin-Abbott, Molly J.; Driscoll, Charles T.

2011-01-01

Human activities have greatly increased nitrogen emissions and deposition across large areas of Earth. Although nitrogen is an essential nutrient for plant growth, too much nitrogen in excess of critical loads leads to losses of biodiversity, soil and stream acidification, nutrient imbalances, and other deleterious effects. In a new report quantifying critical loads of nitrogen deposition across the United States, USGS scientist Steve Perakis and co-authors provided a chapter about responses of marine west coast forests. Much of this region is understudied with respect to nitrogen deposition, and in this chapter the authors identify known adverse effects and estimate critical loads of nitrogen deposition for western Oregon and Washington and southeast Alaska forests. Perakis also contributed to the synthesis chapter, which includes background, objectives, advantages and uncertainties of critical loads, an overview of critical loads across U.S. ecoregions, and other topics.

Effect of stiffness characteristics on the response of composite grid-stiffened structures

NASA Technical Reports Server (NTRS)

Ambur, Damodar R.; Rehfield, Lawrence W.

1991-01-01

A study of the effect of stiffness discontinuities and structural parameters on the response of continuous-filament grid-stiffened flat panels is presented. The buckling load degradation due to manufacturing-introduced stiffener discontinuities associated with a filament cut-and-add approach at the stiffener intersections is investigated. The degradation of buckling resistance in isogrid flat panels subjected to uni-axial compression and combined axial compression and shear loading conditions and induced damage is quantified using FEM. The combined loading case is the most critical one. Nonsolid stiffener cross sections, such as a foam-filled blade or hat with a 0-deg dominant cap, result in grid-stiffened structures that are structurally very efficient for wing and fuselage applications. The results of a study of the ability of grid-stiffened structural concepts to enhance the effective Poisson's ratio of a panel are presented. Grid-stiffened concepts create a highly effective Poisson's ratio, which can produce large camber deformations for certain elastic tailoring applications.

Systems and applications analysis for concentrating photovoltaic-thermal systems

NASA Astrophysics Data System (ADS)

Schwinkendorf, W. E.

Numerical simulations were carried out of the performance, costs, and land use requirements of five commercial and six residential applications of combined photovoltaic-thermal (PVT) power plants. Line focus Fresnel concentrators (LFF) systems were selected after a simulated comparison of different PVT systems. Load profiles were configured from industrial data and ASHRAE and building codes. Assumptions included costs of $1/Wp, 0.15 efficiency, and a cost of $275/sq m, as well as a 25 percent solar tax credit. The calculations showed that a significant low temperature thermal load must be available, but no heat recovery system. Industrial situations were identified which favor solar thermal energy alone rather than a combined system. The thermal energy displacement was determined to be the critical factor in assessing the economics of the PVT systems.

Buckling Analysis of a Honeycomb-Core Composite Cylinder with Initial Geometric Imperfections

NASA Technical Reports Server (NTRS)

Cha, Gene; Schultz, Marc R.

2013-01-01

Thin-walled cylindrical shell structures often have buckling as the critical failure mode, and the buckling of such structures can be very sensitive to small geometric imperfections. The buckling analyses of an 8-ft-diameter, 10-ft-long honeycomb-core composite cylinder loaded in pure axial compression is discussed in this document. Two loading configurations are considered configuration 1 uses simple end conditions, and configuration 2 includes additional structure that may more closely approximate experimental loading conditions. Linear eigenvalue buckling analyses and nonlinear analyses with and without initial geometric imperfections were performed on both configurations. The initial imperfections were introduced in the shell by applying a radial load at the midlength of the cylinder to form a single inward dimple. The critical bifurcation buckling loads are predicted to be 924,190 lb and 924,020 lb for configurations 1 and 2, respectively. Nonlinear critical buckling loads of 918,750 lb and 954,900 lb were predicted for geometrically perfect configurations 1 and 2, respectively. Lower-bound critical buckling loads for configurations 1 and 2 with radial perturbations were found to be 33% and 36% lower, respectively, than the unperturbed critical loads. The inclusion of the load introduction cylinders in configuration 2 increased the maximum bending-boundary-layer rotation up to 11%.

Design for cyclic loading endurance of composites

NASA Technical Reports Server (NTRS)

Shiao, Michael C.; Murthy, Pappu L. N.; Chamis, Christos C.; Liaw, Leslie D. G.

1993-01-01

The application of the computer code IPACS (Integrated Probabilistic Assessment of Composite Structures) to aircraft wing type structures is described. The code performs a complete probabilistic analysis for composites taking into account the uncertainties in geometry, boundary conditions, material properties, laminate lay-ups, and loads. Results of the analysis are presented in terms of cumulative distribution functions (CDF) and probability density function (PDF) of the fatigue life of a wing type composite structure under different hygrothermal environments subjected to the random pressure. The sensitivity of the fatigue life to a number of critical structural/material variables is also computed from the analysis.

Damage Detection in Railway Prestressed Concrete Sleepers using Acoustic Emission

NASA Astrophysics Data System (ADS)

Clark, A.; Kaewunruen, S.; Janeliukstis, R.; Papaelias, M.

2017-10-01

Prestressed concrete sleepers (or railroad ties) are safety-critical elements in railway tracks that distribute the wheel loads from the rails to the track support system. Over a period of time, the concrete sleepers age and deteriorate in addition to experiencing various types of static and dynamic loading conditions, which are attributable to train operations. In many cases, structural cracks can develop within the sleepers due to high intensity impact loads or due to poor track maintenance. Often, cracks of sleepers develop and present at the midspan due to excessive negative bending. These cracks can cause broken sleepers and sometimes called ‘center bound’ problem in railway lines. This paper is the world first to present an application of non-destructive acoustic emission technology for damage detection in railway concrete sleepers. It presents experimental investigations in order to detect center-bound cracks in railway prestressed concrete sleepers. Experimental laboratory testing involves three-point bending tests of four concrete sleepers. Three-point bending tests correspond to a real failure mode, when the loads are not transferred uniformly to the ballast support. It is observed that AE sensing provides an accurate means for detecting the location and magnitude of cracks in sleepers. Sensor location criticality is also highlighted in the paper to demonstrate the reliability-based damage detection of the sleepers.

Use of Biotechnological Devices in the Quantification of Psychophysiological Workload of Professional Chess Players.

PubMed

Fuentes, Juan P; Villafaina, Santos; Collado-Mateo, Daniel; de la Vega, Ricardo; Gusi, Narcis; Clemente-Suárez, Vicente Javier

2018-01-19

Psychophysiological requirements of chess players are poorly understood, and periodization of training is often made without any empirical basis. For this reason, the aim of the present study was to investigate the psychophysiological response and quantify the player internal load during, and after playing a chess game. The participant was an elite 33 year-old male chess player ranked among the 300 best chess players in the world. Thus, cortical arousal by critical flicker fusion threshold, electroencephalogram by the theta Fz/alpha Pz ratio and autonomic modulation by heart rate variability were analyzed. Data revealed that cortical arousal by critical flicker fusion threshold and theta Fz/alpha Pz ratio increased and heart rate variability decreased during chess game. All these changes indicated that internal load increased during the chess game. In addition, pre-activation was detected in pre-game measure, suggesting that the prefrontal cortex might be preparatory activated. For these reasons, electroencephalogram, critical flicker fusion threshold and heart rate variability analysis may be highly applicable tools to control and monitor workload in chess player.

Sliding contact fracture of dental ceramics: Principles and validation

PubMed Central

Ren, Linlin; Zhang, Yu

2014-01-01

Ceramic prostheses are subject to sliding contact under normal and tangential loads. Accurate prediction of the onset of fracture at two contacting surfaces holds the key to greater long-term performance of these prostheses. In this study, building on stress analysis of Hertzian contact and considering fracture criteria for linear elastic materials, a constitutive fracture mechanics relation was developed to incorporate the critical fracture load with the contact geometry, coefficient of friction and material fracture toughness. Critical loads necessary to cause fracture under a sliding indenter were calculated from the constitutive equation, and compared with the loads predicted from elastic stress analysis in conjunction with measured critical load for frictionless normal contact—a semi-empirical approach. The major predictions of the models were calibrated with experimentally determined critical loads of current and future dental ceramics after contact with a rigid spherical slider. Experimental results conform with the trends predicted by the models. PMID:24632538

Canadian experiences in development of critical loads for sulphur and nitrogen

Treesearch

Shaun Watmough; Julian Aherne; Paul Arp; Ian DeMerchant; Rock Ouimet

2006-01-01

Critical loads are a broad-scale modelling approach designed to assess the potential risk of pollutants to ecosystems. A description of the methodology for estimating critical loads (sulphur and nitrogen) for acid deposition (CL(A)) for upland forests in eastern Canada is presented, using a case study in central Ontario. In eastern Canada, CL(A) have been calculated...

A conceptual framework: redifining forests soil's critical acid loads under a changing climate

Treesearch

Steven G. McNulty; Johnny L. Boggs

2010-01-01

Federal agencies of several nations have or are currently developing guidelines for critical forest soil acid loads. These guidelines are used to establish regulations designed to maintain atmospheric acid inputs below levels shown to damage forests and streams. Traditionally, when the critical soil acid load exceeds the amount of acid that the ecosystem can absorb, it...

Estimates of critical acid loads and exceedances for forest soils across the conterminous United States

Treesearch

Steven G. McNulty; Erika C. Cohen; Jennifer A. Moore Myers; Timothy J. Sullivan; Harbin Li

2007-01-01

Concern regarding the impacts of continued nitrogen and sulfur deposition on ecosystem health has prompted the development of critical acid load assessments for forest soils. A critical acid load is a quantitative estimate of exposure to one or more pollutants at or above which harmful acidification-related effects on sensitive elements of the environment occur. A...

Ramp compression of a metallic liner driven by a shaped 5 MA current on the SPHINX machine

NASA Astrophysics Data System (ADS)

d'Almeida, T.; Lassalle, F.; Morell, A.; Grunenwald, J.; Zucchini, F.; Loyen, A.; Maysonnave, T.; Chuvatin, A.

2014-05-01

SPHINX is a 6MA, 1-us Linear Transformer Driver operated by the CEA Gramat (France) and primarily used for imploding Z-pinch loads for radiation effects studies. A method for performing magnetic ramp compression experiments was developed using a compact Dynamic Load Current Multiplier inserted between the convolute and the load, to shape the initial current pulse. We present the overall experimental configuration chosen for these experiments and initial results obtained over a set of experiments on an aluminum cylindrical liner. Current profiles measured at various critical locations across the system, are in good agreement with simulated current profiles. The liner inner free surface velocity measurements agree with the hydrocode results obtained using the measured load current as the input. The potential of the technique in terms of applications and achievable ramp pressure levels lies in the prospects for improving the DLCM efficiency.

The effect of ion plated silver and sliding friction on tensile stress-induced cracking in aluminum oxide

NASA Technical Reports Server (NTRS)

Sliney, Harold E.; Spalvins, Talivaldis

1991-01-01

A Hertzian analysis of the effect of sliding friction on contact stresses in alumina is used to predict the critical load for crack generation. The results for uncoated alumina and alumina coated with ion plated silver are compared. Friction coefficient inputs to the analysis are determined experimentally with a scratch test instrument employing an 0.2 mm radius diamond stylus. A series of scratches were made at constant load increments on coated and uncoated flat alumina surfaces. Critical loads for cracking are detected by microscopic examination of cross sections of scratches made at various loads and friction coefficients. Acoustic emission (AE) and friction trends were also evaluated as experimental techniques for determining critical loads for cracking. Analytical predictions correlate well with micrographic evidence and with the lowest load at which AE is detected in multiple scratch tests. Friction/load trends are not good indicators of early crack formation. Lubrication with silver films reduced friction and thereby increased the critical load for crack initiation in agreement with analytical predictions.

The effect of ion-plated silver and sliding friction on tensile stress-induced cracking in aluminum oxide

NASA Technical Reports Server (NTRS)

Sliney, Harold E.; Spalvins, Talivaldis

1993-01-01

A Hertzian analysis of the effect of sliding friction on contact stresses in alumina is used to predict the critical load for crack generation. The results for uncoated alumina and alumina coated with ion plated silver are compared. Friction coefficient inputs to the analysis are determined experimentally with a scratch test instrument employing an 0.2 mm radius diamond stylus. A series of scratches were made at constant load increments on coated and uncoated flat alumina surfaces. Critical loads for cracking are detected by microscopic examination of cross sections of scratches made at various loads and friction coefficients. Acoustic emission (AE) and friction trends were also evaluated as experimental techniques for determining critical loads for cracking. Analytical predictions correlate well with micrographic evidence and with the lowest load at which AE is detected in multiple scratch tests. Friction/load trends are not good indicators of early crack formation. Lubrication with silver films reduced friction and thereby increased the critical load for crack initiation in agreement with analytical predictions.

Creep Behavior of Structural Insulated Panels (SIPS): Results from a Pilot Study

Treesearch

Dwight McDonald; Marshall Begel; C. Adam Senalik; Robert Ross; Thomas D. Skaggs; Borjen Yeh; Thomas Williamson

2014-01-01

Structural insulated panels (SIPs) have been recognized as construction materials in the International Residential Code (IRC) since 2009. Although most SIPs are used in wall applications, they can also be used as roof or floor panels that are subjected to long-term transverse loading, for which SIP creep performance may be critical in design. However, limited...

The Application of Multiobjective Evolutionary Algorithms to an Educational Computational Model of Science Information Processing: A Computational Experiment in Science Education

ERIC Educational Resources Information Center

Lamb, Richard L.; Firestone, Jonah B.

2017-01-01

Conflicting explanations and unrelated information in science classrooms increase cognitive load and decrease efficiency in learning. This reduced efficiency ultimately limits one's ability to solve reasoning problems in the science. In reasoning, it is the ability of students to sift through and identify critical pieces of information that is of…

Achieving the Promise of Therapeutic Extracellular Vesicles: The Devil is in Details of Therapeutic Loading.

PubMed

Sutaria, Dhruvitkumar S; Badawi, Mohamed; Phelps, Mitch A; Schmittgen, Thomas D

2017-05-01

Extracellular vesicles (EVs) represent a class of cell secreted organelles which naturally contain biomolecular cargo such as miRNA, mRNA and proteins. EVs mediate intercellular communication, enabling the transfer of functional nucleic acids from the cell of origin to the recipient cells. In addition, EVs make an attractive delivery vehicle for therapeutics owing to their increased stability in circulation, biocompatibility, low immunogenicity and toxicity profiles. EVs can also be engineered to display targeting moieties on their surfaces which enables targeting to desired tissues, organs or cells. While much has been learned on the role of EVs as cell communicators, the field of therapeutic EV application is currently under development. Critical to the future success of EV delivery system is the description of methods by which therapeutics can be successfully and efficiently loaded within the EVs. Two methods of loading of EVs with therapeutic cargo exist, endogenous and exogenous loading. We have therefore focused this review on describing the various published approaches for loading EVs with therapeutics.

Dynamic Modeling, Model-Based Control, and Optimization of Solid Oxide Fuel Cells

NASA Astrophysics Data System (ADS)

Spivey, Benjamin James

2011-07-01

Solid oxide fuel cells are a promising option for distributed stationary power generation that offers efficiencies ranging from 50% in stand-alone applications to greater than 80% in cogeneration. To advance SOFC technology for widespread market penetration, the SOFC should demonstrate improved cell lifetime and load-following capability. This work seeks to improve lifetime through dynamic analysis of critical lifetime variables and advanced control algorithms that permit load-following while remaining in a safe operating zone based on stress analysis. Control algorithms typically have addressed SOFC lifetime operability objectives using unconstrained, single-input-single-output control algorithms that minimize thermal transients. Existing SOFC controls research has not considered maximum radial thermal gradients or limits on absolute temperatures in the SOFC. In particular, as stress analysis demonstrates, the minimum cell temperature is the primary thermal stress driver in tubular SOFCs. This dissertation presents a dynamic, quasi-two-dimensional model for a high-temperature tubular SOFC combined with ejector and prereformer models. The model captures dynamics of critical thermal stress drivers and is used as the physical plant for closed-loop control simulations. A constrained, MIMO model predictive control algorithm is developed and applied to control the SOFC. Closed-loop control simulation results demonstrate effective load-following, constraint satisfaction for critical lifetime variables, and disturbance rejection. Nonlinear programming is applied to find the optimal SOFC size and steady-state operating conditions to minimize total system costs.

Nitrogen critical loads and management alternatives for N-impacted ecosystems in California

Treesearch

M.E. Fenn; E.B. Allen; S.B. Weiss; S. Jovan; L. Geiser; G.S. Tonnesen; R.F. Johnson; L.E. Rao; B.S. Gimeno; F. Yuan; T. Meixner; A. Bytnerowicz

2010-01-01

Empirical critical loads for N deposition effects and maps showing areas projected to be in exceedance of the critical load (CL) are given for seven major vegetation types in California. Thirty-five percent of the land area for these vegetation types (99,639 km2) is estimated to be in excess of the N CL. Low CL values (3–8...

Critical loads as a policy tool for protecting ecosystems from the effects of air pollutants

Treesearch

Douglas A. Burns; Tamara Blett; Richard Haeuber; Linda H. Pardo

2008-01-01

Framing the effects of air pollutants on ecosystems in terms of a "critical load" provides a meaningful approach for research scientists to communicate policy-relevant science to air-quality policy makers and natural resource managers. A critical-loads approach has been widely used to shape air-pollutant control policy in Europe since the 1980s, yet has only...

Critical loads of nitrogen deposition and critical levels of atmospheric ammonia for semi-natural Mediterranean evergreen woodlands

NASA Astrophysics Data System (ADS)

Pinho, P.; Theobald, M. R.; Dias, T.; Tang, Y. S.; Cruz, C.; Martins-Loução, M. A.; Máguas, C.; Sutton, M.; Branquinho, C.

2012-03-01

Nitrogen (N) has emerged in recent years as a key factor associated with global changes, with impacts on biodiversity, ecosystems functioning and human health. In order to ameliorate the effects of excessive N, safety thresholds such as critical loads (deposition fluxes) and levels (concentrations) can be established. Few studies have assessed these thresholds for semi-natural Mediterranean ecosystems. Our objective was therefore to determine the critical loads of N deposition and long-term critical levels of atmospheric ammonia for semi-natural Mediterranean evergreen woodlands. We have considered changes in epiphytic lichen communities, one of the most sensitive comunity indicators of excessive N in the atmosphere. Based on a classification of lichen species according to their tolerance to N we grouped species into response functional groups, which we used as a tool to determine the critical loads and levels. This was done for a Mediterranean climate in evergreen cork-oak woodlands, based on the relation between lichen functional diversity and modelled N deposition for critical loads and measured annual atmospheric ammonia concentrations for critical levels, evaluated downwind from a reduced N source (a cattle barn). Modelling the highly significant relationship between lichen functional groups and annual atmospheric ammonia concentration showed the critical level to be below 1.9 μg m-3, in agreement with recent studies for other ecosystems. Modelling the highly significant relationship between lichen functional groups and N deposition showed that the critical load was lower than 26 kg (N) ha-1 yr-1, which is within the upper range established for other semi-natural ecosystems. Taking into account the high sensitivity of lichen communities to excessive N, these values should aid development of policies to protect Mediterranean woodlands from the initial effects of excessive N.

Utilizing an Energy Management System with Distributed Resources to Manage Critical Loads and Reduce Energy Costs

DTIC Science & Technology

2014-09-01

peak shaving, conducting power factor correction, matching critical load to most efficient distributed resource, and islanding a system during...photovoltaic arrays during islanding, and power factor correction, the implementation of the ESS by itself is likely to prove cost prohibitive. The DOD...These functions include peak shaving, conducting power factor correction, matching critical load to most efficient distributed resource, and islanding a

Impact and damage of an armor composite

NASA Astrophysics Data System (ADS)

Resnyansky, A. D.; Parry, S.; Bourne, N. K.; Townsend, D.; James, B. J.

2015-06-01

The use of carbon fiber composites under shock and impact loading in aerospace, defense and automotive applications is increasingly important. Therefore prediction of the composite behavior and damage in these conditions is critical. Influence of anisotropy, fiber orientation and the rate of loading during the impact is considered in the present study and validated by comparison with experiments. The experiments deal with the plane, ballistic and Taylor impacts accompanied by high-speed photography observations and tomography of recovered samples. The CTH hydrocode is employed as the modeling platform with an advanced rate sensitive material model used for description of the deformation and damage of the transversely isotropic composite material.

Slip measurement in a frictional connection by torsional LDV

NASA Astrophysics Data System (ADS)

Schäfer, Günter; Lohrengel, Armin; Hilgermann, Jan Lukas

2016-06-01

Frictional shaft-hub connections are often used in drive train applications. The classic version is fitted by a temperature difference between the cold shaft und the hot hub, or simply axial press-fitted at room temperature. The critical point in this type of connection is the contact pressure at the edge of the hub regarding the relative deformation between the shaft and the hub under dynamic operating loads. Another innovative version, the internal press-fit, leads to a tolerance insensitive lightweight design using a tube as shaft and a controlled plastic deformation by internal high pressure. The internal press-fit connection is a special research topic at the IMW, TU Clausthal. The use of internal high pressure allows to trigger the contact pressure at the edge of the hub on an optimum value. The product of contact pressure and slipway is the key value to determine the fatigue resistance and load capacity of this kind of connection. /1/ and /2/ defined a critical range of slipway amplitudes between 5 and 25 µm for fretting. The normal use and main function of a shaft-hub connection is the transmission of torque. Regarding the different torsional stiffness of the shaft and the hub, there will be a difference in deformation in the contact zone between the shaft and the hub, which is necessary to measure on a probe under oscillating torque load. The measurement on the test-rig in /3/ was done with a POLYTEC torsional LDV (controller OFV-4000, sensor head OFV-400). In general the continuously oscillating torque load allowed a serial measurement of the torsional movement of the shaft and the hub. The difference of the two maximum values is the expected slipway between the two parts in the critical zone at the edge of the hub. The main benefits of the Torsional LDV in this application are the very small measuring point (next to the contact), no influence on the probe, no special preparation of the probe and a really good resolution. The paper gives an overview to the technical background of the measured value, to the measuring setup, to the other used measuring techniques and to the measuring results.

Preparation and characterization of temperature-responsive magnetic composite particles for multi-modal cancer therapy.

PubMed

Yao, Aihua; Chen, Qi; Ai, Fanrong; Wang, Deping; Huang, Wenhai

2011-10-01

The temperature-responsive magnetic composite particles were synthesized by emulsion-free polymerization of N-isopropylacrylamide (NIPAAm) and acrylamide (Am) in the presence of oleic acid-modified Fe(3)O(4) nanoparticles. The magnetic properties and heat generation ability of the composite particles were characterized. Furthermore, temperature and alternating magnetic field (AMF) triggered drug release behaviors of vitamin B(12)-loaded composite particles were also examined. It was found that composite particles enabled drug release to be controlled through temperature changes in the neighborhood of lower critical solution temperature. Continuous application of AMF resulted in an accelerated release of the loaded drug. On the other hand, intermittent AMF application to the composite particles resulted in an "on-off", stepwise release pattern. Longer release duration and larger overall release could be achieved by intermittent application of AMF as compared to continuous magnetic field. Such composite particles may be used for magnetic drug targeting followed by simultaneous hyperthermia and drug release.

Worm Gear With Hydrostatic Engagement

NASA Technical Reports Server (NTRS)

Chaiko, Lev I.

1994-01-01

In proposed worm-gear transmission, oil pumped at high pressure through meshes between teeth of gear and worm coil. Pressure in oil separates meshing surfaces slightly, and oil reduces friction between surfaces. Conceived for use in drive train between gas-turbine engine and rotor of helicopter. Useful in other applications in which weight critical. Test apparatus simulates and measures some loading conditions of proposed worm gear with hydrostatic engagement.

Identification of dynamic load for prosthetic structures.

PubMed

Zhang, Dequan; Han, Xu; Zhang, Zhongpu; Liu, Jie; Jiang, Chao; Yoda, Nobuhiro; Meng, Xianghua; Li, Qing

2017-12-01

Dynamic load exists in numerous biomechanical systems, and its identification signifies a critical issue for characterizing dynamic behaviors and studying biomechanical consequence of the systems. This study aims to identify dynamic load in the dental prosthetic structures, namely, 3-unit implant-supported fixed partial denture (I-FPD) and teeth-supported fixed partial denture. The 3-dimensional finite element models were constructed through specific patient's computerized tomography images. A forward algorithm and regularization technique were developed for identifying dynamic load. To verify the effectiveness of the identification method proposed, the I-FPD and teeth-supported fixed partial denture structures were investigated to determine the dynamic loads. For validating the results of inverse identification, an experimental force-measuring system was developed by using a 3-dimensional piezoelectric transducer to measure the dynamic load in the I-FPD structure in vivo. The computationally identified loads were presented with different noise levels to determine their influence on the identification accuracy. The errors between the measured load and identified counterpart were calculated for evaluating the practical applicability of the proposed procedure in biomechanical engineering. This study is expected to serve as a demonstrative role in identifying dynamic loading in biomedical systems, where a direct in vivo measurement may be rather demanding in some areas of interest clinically. Copyright © 2017 John Wiley & Sons, Ltd.

In-vitro development of a temporal abutment screw to protect osseointegration in immediate loaded implants.

PubMed

García-Roncero, Herminio; Caballé-Serrano, Jordi; Cano-Batalla, Jordi; Cabratosa-Termes, Josep; Figueras-Álvarez, Oscar

2015-04-01

In this study, a temporal abutment fixation screw, designed to fracture in a controlled way upon application of an occlusal force sufficient to produce critical micromotion was developed. The purpose of the screw was to protect the osseointegration of immediate loaded single implants. Seven different screw prototypes were examined by fixing titanium abutments to 112 Mozo-Grau external hexagon implants (MG Osseous®; Mozo-Grau, S.A., Valladolid, Spain). Fracture strength was tested at 30° in two subgroups per screw: one under dynamic loading and the other without prior dynamic loading. Dynamic loading was performed in a single-axis chewing simulator using 150,000 load cycles at 50 N. After normal distribution of obtained data was verified by Kolmogorov-Smirnov test, fracture resistance between samples submitted and not submitted to dynamic loading was compared by the use of Student's t-test. Comparison of fracture resistance among different screw designs was performed by the use of one-way analysis of variance. Confidence interval was set at 95%. Fractures occurred in all screws, allowing easy retrieval. Screw Prototypes 2, 5 and 6 failed during dynamic loading and exhibited statistically significant differences from the other prototypes. Prototypes 2, 5 and 6 may offer a useful protective mechanism during occlusal overload in immediate loaded implants.

High-loading Fe2O3/SWNT composite films for lithium-ion battery applications

NASA Astrophysics Data System (ADS)

Wang, Ying; Guo, Jiahui; Li, Li; Ge, Yali; Li, Baojun; Zhang, Yingjiu; Shang, Yuanyuan; Cao, Anyuan

2017-08-01

Single-walled carbon nanotube (SWNT) films are a potential candidate as porous conductive electrodes for energy conversion and storage; tailoring the loading and distribution of active materials grafted on SWNTs is critical for achieving maximum performance. Here, we show that as-synthesized SWNT samples containing residual Fe catalyst can be directly converted to Fe2O3/SWNT composite films by thermal annealing in air. The mass loading of Fe2O3 nanoparticles is tunable from 63 wt% up to 96 wt%, depending on the annealing temperature (from 450 °C to 600 °C), while maintaining the porous network structure. Interconnected SWNT networks containing high-loading active oxides lead to synergistic effect as an anode material for lithium ion batteries. The performance is improved consistently with increasing Fe2O3 loading. As a result, our Fe2O3/SWNT composite films exhibit a high reversible capacity (1007.1 mA h g-1 at a current density of 200 mA g-1), excellent rate capability (384.9 mA h g-1 at 5 A g-1) and stable cycling performance with the discharge capacity up to 567.1 mA h g-1 after 600 cycles at 2 A g-1. The high-loading Fe2O3/SWNT composite films have potential applications as nanostructured electrodes for various energy devices such as supercapacitors and Li-ion batteries.

Critical levels and loads and the regulation of industrial emissions in northwest British Columbia, Canada

NASA Astrophysics Data System (ADS)

Williston, P.; Aherne, J.; Watmough, S.; Marmorek, D.; Hall, A.; de la Cueva Bueno, P.; Murray, C.; Henolson, A.; Laurence, J. A.

2016-12-01

Northwest British Columbia, Canada, a sparsely populated and largely pristine region, is targeted for rapid industrial growth owing to the modernization of an aluminum smelter and multiple proposed liquefied natural gas (LNG) facilities. Consequently, air quality in this region is expected to undergo considerable changes within the next decade. In concert, the increase in LNG capacity driven by gas production from shale resources across North America has prompted environmental concerns and highlighted the need for science-based management decisions regarding the permitting of air emissions. In this study, an effects-based approach widely-used to support transboundary emissions policy negotiations was used to assess industrial air emissions in the Kitimat and Prince Rupert airsheds under permitted and future potential industrial emissions. Critical levels for vegetation of SO2 and NO2 and critical loads of acidity and nutrient nitrogen for terrestrial and aquatic ecosystems were estimated for both regions and compared with modelled concentration and deposition estimates to identify the potential extent and magnitude of ecosystem impacts. The critical level for SO2 was predicted to be exceeded in an area ranging from 81 to 251 km2 in the Kitimat airshed owing to emissions from an existing smelter, compared with <1 km2 in Prince Rupert under the lowest to highest emissions scenarios. In contrast, the NO2 critical level was not exceeded in Kitimat, and ranged from 4.5 to 6 km2 in Prince Rupert owing to proposed LNG related emissions. Predicted areal exceedance of the critical load of acidity for soil ranged from 1 to 28 km2 in Kitimat and 4-10 km2 in Prince Rupert, while the areal exceedance of empirical critical load for nutrient N was predicted to be greater in the Prince Rupert airshed (20-94 km2) than in the Kitimat airshed (1-31 km2). The number of lakes that exceeded the critical load of acidity did not vary greatly across emissions scenarios in the Kitimat (21-23 out of 80 sampled lakes) and Prince Rupert (0 out of 35 sampled lakes) airsheds. While critical loads have been widely used to underpin international emissions reductions of transboundary pollutants, it is clear that they can also play an important role in managing regional air emissions. In the current study, exceedance of critical levels and loads suggests that industrial emissions from the nascent LNG export sector may require careful regulation to avoid environmental impacts. Emissions management from LNG export facilities in other regions should consider critical levels and loads analyses to ensure industrial development is synergistic with ecosystem protection. While recognizing uncertainties in dispersion modelling, critical load estimates, and subsequent effects, the critical levels and loads approach is being used to inform regulatory decisions in British Columbia to prevent impacts that have been well documented in other regions.

MYRRHA: A multipurpose nuclear research facility

NASA Astrophysics Data System (ADS)

Baeten, P.; Schyns, M.; Fernandez, Rafaël; De Bruyn, Didier; Van den Eynde, Gert

2014-12-01

MYRRHA (Multi-purpose hYbrid Research Reactor for High-tech Applications) is a multipurpose research facility currently being developed at SCK•CEN. MYRRHA is based on the ADS (Accelerator Driven System) concept where a proton accelerator, a spallation target and a subcritical reactor are coupled. MYRRHA will demonstrate the ADS full concept by coupling these three components at a reasonable power level to allow operation feedback. As a flexible irradiation facility, the MYRRHA research facility will be able to work in both critical as subcritical modes. In this way, MYRRHA will allow fuel developments for innovative reactor systems, material developments for GEN IV and fusion reactors, and radioisotope production for medical and industrial applications. MYRRHA will be cooled by lead-bismuth eutectic and will play an important role in the development of the Pb-alloys technology needed for the LFR (Lead Fast Reactor) GEN IV concept. MYRRHA will also contribute to the study of partitioning and transmutation of high-level waste. Transmutation of minor actinides (MA) can be completed in an efficient way in fast neutron spectrum facilities, so both critical reactors and subcritical ADS are potential candidates as dedicated transmutation systems. However critical reactors heavily loaded with fuel containing large amounts of MA pose reactivity control problems, and thus safety problems. A subcritical ADS operates in a flexible and safe manner, even with a core loading containing a high amount of MA leading to a high transmutation rate. In this paper, the most recent developments in the design of the MYRRHA facility are presented.

Biomechanical and biological aspects of defect treatment in fractures using helical plates.

PubMed

Perren, S M; Regazzoni, P; Fernandez, A A D

2014-01-01

The clinical case of figure 1 through figure 11 shows a series of impressive failures of plate fixation. The plates were repeatedly applied bridging a comminuted bone segment in a heavy patient. The biomechanical analysis elaborates why this happened and proposes an unconventional procedure to prevent this failure with a minimally invasive procedure. A plate bridging an open gap or a defect in a long bone diaphysis is exposed to full functional load. According to clinical observations such plate application often fails even without external load such as weight bearing. The plate risks to break through fatigue when exposed during a long time to cyclic loading. This type of failure has been observed even with broad plates as well in femoral as in tibiae. The first option to avoid such failure consists in protecting the plate by installing load sharing between plate and either bone or an additional implant. This reduces the load carried by the plate to a safe level. Load sharing with bone may be installed at surgery by establishing solid mechanical bridge between the two main fragments of the fractured bone. The optimal load sharing relies on a solid compressed contact between the main fragments. It can be established because the bone is able to take a large load which results in optimal protection of the plate. In the case of an extended comminuted bone segment it may be very difficult, traumatizing and inefficient to reconstruct the bone. In the present case it was impossible to establish load sharing through the bone. The second option protecting the plate is provided by callus bridging of the gap or defect. The formation of a solid callus bridge takes time but the fatigue failure of the plate also takes time. Therefore, the callus bridge may prevent a late fatigue failure. The surgeon may select one of several options: - Replacing the lack of bone support using a second plate which immediately alleviates plate loading. The drawback of application of a second conventional plate is the extent of surgical trauma at the critical site of healing. - Shingling and/or applying an autologous cancellous bone graft: This procedure provides initially no relevant load sharing but will do so after a couple of weeks. The mechanical coupling of the comparably soft graft and the main fracture fragments presents little problems. Applying a cortical bone graft: Such a graft does provide initial only small load sharing and does a less good job inducing callus than a cancellous graft. Furthermore, the coupling by callus between a somewhat rigid bone graft and the mobile main fracture fragments requires a solid maintained contact. If the cortical graft is fixed using implants with small contact area to the graft such as screws or cerclage loops, the local stress may be critical and the graft may break. When the cortical graft is fixed with cerclage wires the procedure must take into account the limited strength of the individual cerclage. Therefore multiple and well-spaced cerclages are required and may lead to success especially if an intramedullary component of the implant contributes to protection (6). The degree of unloading depends apparently on the stiffness of the material of the protecting splint. Though, more important is the effect of the dimensions of the splint. While titanium as a material is about 50% less stiff than steel, the thickness of the implant changes the stiffness with the third power. That is doubling the thickness results in eightfold increased stiffness. When considering the unloading by application of a second plate the leverage of the second plate plays an important role. The larger the distance between the axis of bending and the second implant the larger the protecting effect. The helical plate (2, 3, 7) as introduced by A.A.D. Fernandez offers biological and mechanical advantages. It can be applied without touching the fracture site maintaining the critical biology intact and provides mechanically efficient unloading. Its application is fairly simple: The helical plate is modified conventional long and small plate that is twisted between its ends about 90 degrees. The twist is applied using "bending irons" (4, 5, 8) whereby the force required is small and the exact degree of twist is not critical. Therefore the twist is applicable operating bending irons by hand. Assuming a situation where a plate bridging a defect or non-union has failed the broken plate is replaced by a similar implant: At the distal end of the bone fracture and opposite to the surgical approach a small incision allows to slide in the helical plate in such a way that proximally the plate ends on the same side of the limb as the replaced plate. Ideally the two plate ends meet and the application of the helical plate does not ask for an additional surgical exposure at this location. Otherwise a small minimally invasive exposure is required. The helical plate is then fixed to the main bone fragments using a couple of locked screws. The following case demonstrates the use and efficiency of the helical plate saving a situation where multiple attempts using conventional plates had failed. The successful final treatment of this case was performed by A. A. D. Fernandez.

An assessment of spacecraft target mode selection methods

NASA Astrophysics Data System (ADS)

Mercer, J. F.; Aglietti, G. S.; Remedia, M.; Kiley, A.

2017-11-01

Coupled Loads Analyses (CLAs), using finite element models (FEMs) of the spacecraft and launch vehicle to simulate critical flight events, are performed in order to determine the dynamic loadings that will be experienced by spacecraft during launch. A validation process is carried out on the spacecraft FEM beforehand to ensure that the dynamics of the analytical model sufficiently represent the behavior of the physical hardware. One aspect of concern is the containment of the FEM correlation and update effort to focus on the vibration modes which are most likely to be excited under test and CLA conditions. This study therefore provides new insight into the prioritization of spacecraft FEM modes for correlation to base-shake vibration test data. The work involved example application to large, unique, scientific spacecraft, with modern FEMs comprising over a million degrees of freedom. This comprehensive investigation explores: the modes inherently important to the spacecraft structures, irrespective of excitation; the particular 'critical modes' which produce peak responses to CLA level excitation; an assessment of several traditional target mode selection methods in terms of ability to predict these 'critical modes'; and an indication of the level of correlation these FEM modes achieve compared to corresponding test data. Findings indicate that, although the traditional methods of target mode selection have merit and are able to identify many of the modes of significance to the spacecraft, there are 'critical modes' which may be missed by conventional application of these methods. The use of different thresholds to select potential target modes from these parameters would enable identification of many of these missed modes. Ultimately, some consideration of the expected excitations is required to predict all modes likely to contribute to the response of the spacecraft in operation.

Application of a loading dose of colistin methanesulfonate in critically ill patients: population pharmacokinetics, protein binding, and prediction of bacterial kill.

PubMed

Mohamed, Ami F; Karaiskos, Ilias; Plachouras, Diamantis; Karvanen, Matti; Pontikis, Konstantinos; Jansson, Britt; Papadomichelakis, Evangelos; Antoniadou, Anastasia; Giamarellou, Helen; Armaganidis, Apostolos; Cars, Otto; Friberg, Lena E

2012-08-01

A previous pharmacokinetic study on dosing of colistin methanesulfonate (CMS) at 240 mg (3 million units [MU]) every 8 h indicated that colistin has a long half-life, resulting in insufficient concentrations for the first 12 to 48 h after initiation of treatment. A loading dose would therefore be beneficial. The aim of this study was to evaluate CMS and colistin pharmacokinetics following a 480-mg (6-MU) loading dose in critically ill patients and to explore the bacterial kill following the use of different dosing regimens obtained by predictions from a pharmacokinetic-pharmacodynamic model developed from an in vitro study on Pseudomonas aeruginosa. The unbound fractions of colistin A and colistin B were determined using equilibrium dialysis and considered in the predictions. Ten critically ill patients (6 males; mean age, 54 years; mean creatinine clearance, 82 ml/min) with infections caused by multidrug-resistant Gram-negative bacteria were enrolled in the study. The pharmacokinetic data collected after the first and eighth doses were analyzed simultaneously with the data from the previous study (total, 28 patients) in the NONMEM program. For CMS, a two-compartment model best described the pharmacokinetics, and the half-lives of the two phases were estimated to be 0.026 and 2.2 h, respectively. For colistin, a one-compartment model was sufficient and the estimated half-life was 18.5 h. The unbound fractions of colistin in the patients were 26 to 41% at clinical concentrations. Colistin A, but not colistin B, had a concentration-dependent binding. The predictions suggested that the time to 3-log-unit bacterial kill for a 480-mg loading dose was reduced to half of that for the dose of 240 mg.

Application of a Loading Dose of Colistin Methanesulfonate in Critically Ill Patients: Population Pharmacokinetics, Protein Binding, and Prediction of Bacterial Kill

PubMed Central

Karaiskos, Ilias; Plachouras, Diamantis; Karvanen, Matti; Pontikis, Konstantinos; Jansson, Britt; Papadomichelakis, Evangelos; Antoniadou, Anastasia; Giamarellou, Helen; Armaganidis, Apostolos; Cars, Otto; Friberg, Lena E.

2012-01-01

A previous pharmacokinetic study on dosing of colistin methanesulfonate (CMS) at 240 mg (3 million units [MU]) every 8 h indicated that colistin has a long half-life, resulting in insufficient concentrations for the first 12 to 48 h after initiation of treatment. A loading dose would therefore be beneficial. The aim of this study was to evaluate CMS and colistin pharmacokinetics following a 480-mg (6-MU) loading dose in critically ill patients and to explore the bacterial kill following the use of different dosing regimens obtained by predictions from a pharmacokinetic-pharmacodynamic model developed from an in vitro study on Pseudomonas aeruginosa. The unbound fractions of colistin A and colistin B were determined using equilibrium dialysis and considered in the predictions. Ten critically ill patients (6 males; mean age, 54 years; mean creatinine clearance, 82 ml/min) with infections caused by multidrug-resistant Gram-negative bacteria were enrolled in the study. The pharmacokinetic data collected after the first and eighth doses were analyzed simultaneously with the data from the previous study (total, 28 patients) in the NONMEM program. For CMS, a two-compartment model best described the pharmacokinetics, and the half-lives of the two phases were estimated to be 0.026 and 2.2 h, respectively. For colistin, a one-compartment model was sufficient and the estimated half-life was 18.5 h. The unbound fractions of colistin in the patients were 26 to 41% at clinical concentrations. Colistin A, but not colistin B, had a concentration-dependent binding. The predictions suggested that the time to 3-log-unit bacterial kill for a 480-mg loading dose was reduced to half of that for the dose of 240 mg. PMID:22615285

Quantitative Evaluation of 3 DBMS: ORACLE, SEED AND INGRES

NASA Technical Reports Server (NTRS)

Sylto, R.

1984-01-01

Characteristics required for NASA scientific data base management application are listed as well as performance testing objectives. Results obtained for the ORACLE, SEED, and INGRES packages are presented in charts. It is concluded that vendor packages can manage 130 megabytes of data at acceptable load and query rates. Performance tests varying data base designs and various data base management system parameters are valuable to applications for choosing packages and critical to designing effective data bases. An applications productivity increases with the use of data base management system because of enhanced capabilities such as a screen formatter, a reporter writer, and a data dictionary.

Bending and Shear Behavior of Pultruded Glass Fiber Reinforced Polymer Composite Beams With Closed and Open Sections

NASA Astrophysics Data System (ADS)

Estep, Daniel Douglas

Several advantages, such as high strength-to-weight ratio, high stiffness, superior corrosion resistance, and high fatigue and impact resistance, among others, make FRPs an attractive alternative to conventional construction materials for use in developing new structures as well as rehabilitating in-service infrastructure. As the number of infrastructure applications using FRPs grows, the need for the development of a uniform Load and Resistance Factor Design (LRFD) approach, including design procedures and examples, has become paramount. Step-by-step design procedures and easy-to-use design formulas are necessary to assure the quality and safety of FRP structural systems by reducing the possibility of design and construction errors. Since 2008, the American Society of Civil Engineers (ASCE), in coordination with the American Composites Manufacturers Association (ACMA), has overseen the development of the Pre-Standard for Load and Resistance Factor Design (LRFD) of Pultruded Fiber Reinforced Polymer (FRP) Structures using probability-based limit states design. The fifth chapter of the pre-standard focuses on the design of members in flexure and shear under different failure modes, where the current failure load prediction models proposed within have been shown to be highly inaccurate based on experimental data and evaluation performed by researchers at the West Virginia University Constructed Facilities Center. A new prediction model for determining the critical flexural load capacity of pultruded GFRP square and rectangular box beams is presented within. This model shows that the type of failure can be related to threshold values of the beam span-to-depth ratio (L/h) and total flange width-to-thickness ratio (bf /t), resulting in three governing modes of failure: local buckling failure in the compression flange (4 ≤ L/h < 6), combined strain failure at the web-flange junction (6 ≤ L/h ≤ 10), and bending failure in the tension flange (10 < L/h ≤ 42). Broadly, the proposed equations are predicting critical flexural load capacities within +/-22.3% of experimental data for all cases, with over 70% of all experimental data with within +/-10% error. A second prediction model was developed for predicting the critical lateral-torsional buckling (LTB) load for pultruded GFRP open sections, including wide flange (WF) sections and channels. Multiple LTB equations from several sources were considered and applied but yielded inaccurate results, leading to the development of this new critical buckling load prediction model based on the well-established elastic LTB strength equation for steel. By making a series of modifications to equations for calculating the weak axis moment of inertia, torsional warping constant, and torsion constant for open sections, as well as recognizing the influence of the shear lag phenomenon, the critical LTB load is predicted within +/-15.2% of experimental data for all channel and WF specimens tested and evaluated in the study.

Modeling the Interactions Between Multiple Crack Closure Mechanisms at Threshold

NASA Technical Reports Server (NTRS)

Newman, John A.; Riddell, William T.; Piascik, Robert S.

2003-01-01

A fatigue crack closure model is developed that includes interactions between the three closure mechanisms most likely to occur at threshold; plasticity, roughness, and oxide. This model, herein referred to as the CROP model (for Closure, Roughness, Oxide, and Plasticity), also includes the effects of out-of plane cracking and multi-axial loading. These features make the CROP closure model uniquely suited for, but not limited to, threshold applications. Rough cracks are idealized here as two-dimensional sawtooths, whose geometry induces mixed-mode crack- tip stresses. Continuum mechanics and crack-tip dislocation concepts are combined to relate crack face displacements to crack-tip loads. Geometric criteria are used to determine closure loads from crack-face displacements. Finite element results, used to verify model predictions, provide critical information about the locations where crack closure occurs.

Buckling analysis of carbon nanotube bundles under axial compressive, bending and torsional loadings via a structural mechanics model

NASA Astrophysics Data System (ADS)

Lashkari Zadeh, Ali; Shariati, Mahmoud; Torabi, Hamid

2012-11-01

A structural mechanics model is employed for the investigation of the buckling behavior of carbon nanotube bundles of three single-walled carbon nanotubes (SWCNTs) under axial compressive, bending and torsional loadings. The effects of van der Waals (vdW) forces are further modeled using a nonlinear spring element.The effects of different types of boundary conditions are studied for nanotubes with various aspect ratios. The results reveal that bundles comprising longer SWCNTs exhibit lower critical buckling load. Moreover, for the fixed-free boundary condition the rate of critical buckling load reduction is highest, while the lowest critical buckling load occurs. Simulations show good agreement between our model and molecular dynamics results.

Mechanics of a mosquito bite with applications to microneedle design.

PubMed

Ramasubramanian, M K; Barham, O M; Swaminathan, V

2008-12-01

The mechanics of a fascicle insertion into the skin by a mosquito of the type aedes aegypti has been studied experimentally using high-speed video (HSV) imaging, and analytically using a mathematical model. The fascicle is a polymeric microneedle composed of a ductile material, chitin. It has been proposed that the mosquito applies a non-conservative follower force component in addition to the Euler compressive load in order to prevent buckling and penetrate the skin. In addition, the protective sheath surrounding the fascicle (labium) provides lateral support during insertion. The mechanics model presented approximates the fascicle as a slender column supported on an elastic foundation (labium) subjected to non-conservative (Beck) and conservative Euler loads simultaneously at the end. Results show that the lateral support of the fascicle provided by the labium is essential for successful penetration by increasing the critical buckling load by a factor of 5. The non-conservative follower force application increases the buckling load by an additional 20% and may or may not be necessary for successful penetration. Experimental results showing the importance of the labium have been cited to validate the model predictions, in addition to the video observations presented in this work. This understanding may be useful in designing painless needle insertion systems as opposed to miniaturized hypodermic needles.

Dynamics of defect-loaded grain boundary under shear deformation in alpha iron

NASA Astrophysics Data System (ADS)

Yang, L.; Zhou, H. L.; Liu, H.; Gao, F.; Zu, X. T.; Peng, S. M.; Long, X. G.; Zhou, X. S.

2018-02-01

Two symmetric tilt grain boundaries (GBs) (Σ3〈110〉{112} and Σ11〈110〉{332}) in alpha iron were performed to investigate the dynamics of defect-loaded GBs under shear deformation. The results show that the loaded self-interstitial atoms (SIAs) reduce the critical stress of the coupled GB motion in the Σ3 GB, but increase the critical stress in the Σ11 GB. The loaded SIAs in the Σ3 GB easily form 〈111〉 clusters and remain in the bulk when the GB moves away. However, the SIAs move along with the Σ11 GB and combine with the vacancies in the bulk, leading to the defect self-healing. The helium (He) atoms loaded into the GBs significantly affect the coupled GB motion. Once He clusters emit interstitials, the Σ11 GB carries those interstitials away but the Σ3 does not. The loaded He atoms reduce the critical stress of the Σ3 GB, but increase the critical stress of the Σ11 GB.

Influence of the heater material on the critical heat load at boiling of liquids on surfaces with different sizes

NASA Astrophysics Data System (ADS)

Anokhina, E. V.

2010-05-01

Data on critical heat loads q cr for the saturated and unsaturated pool boiling of water and ethanol under atmospheric pressure are reported. It is found experimentally that the critical heat load does not necessarily coincide with the heat load causing burnout of the heater, which should be taken into account. The absolute values of q cr for the boiling of water and ethanol on copper surfaces 65, 80, 100, 120, and 200 μm in diameter; tungsten surface 100 μm in diameter; and nichrome surface 100 μm in diameter are obtained experimentally.

[Valuation of forest damage cost from SO2 emission: a case study in Hunan Province].

PubMed

Hao, Jiming; Li, Ji; Duan, Lei; He, Kebin; Dai, Wennan

2002-11-01

Large amount SO2 emission caused serious damage of forest ecosystem in China and calculation of the damage cost is an important issue for policy-making. However, no applicable method was developed to estimate forest damage under different SO2 emission scenarios. Basing on previous field researches on sulfur-related forest impact in China and recent critical load mapping research, this paper presented a model for forest damage calculation by developing a dose-response function that related the damage to cumulative sulfur critical loads. This model was applied to the forests in Hunan, a province in acid rain control zone in China. Results showed that in the business-as-usual case, SO2 emission in Hunan will increase by 120% from 1995 (8.82 mil. ton) to 2020 (19.56 mil. ton), but damage cost will increase by 4.3 times, reaching 6.19 billion RMB in 2020. Results also showed the measures for SO2 control were cost-effective because the marginal damage cost will be about 6000 RMB per ton SO2 in 2020 in BAU case. At current SO2 emission level, marginal benefit will be about 1500 RMB per ton. Uncertainty analysis demonstrated that this model provides reasonable damage estimates and would therefore be applicable in a broad range of policy settings.

An Enhanced Adaptive Management Approach for Remediation of Legacy Mercury in the South River

PubMed Central

Foran, Christy M.; Baker, Kelsie M.; Grosso, Nancy R.; Linkov, Igor

2015-01-01

Uncertainties about future conditions and the effects of chosen actions, as well as increasing resource scarcity, have been driving forces in the utilization of adaptive management strategies. However, many applications of adaptive management have been criticized for a number of shortcomings, including a limited ability to learn from actions and a lack of consideration of stakeholder objectives. To address these criticisms, we supplement existing adaptive management approaches with a decision-analytical approach that first informs the initial selection of management alternatives and then allows for periodic re-evaluation or phased implementation of management alternatives based on monitoring information and incorporation of stakeholder values. We describe the application of this enhanced adaptive management (EAM) framework to compare remedial alternatives for mercury in the South River, based on an understanding of the loading and behavior of mercury in the South River near Waynesboro, VA. The outcomes show that the ranking of remedial alternatives is influenced by uncertainty in the mercury loading model, by the relative importance placed on different criteria, and by cost estimates. The process itself demonstrates that a decision model can link project performance criteria, decision-maker preferences, environmental models, and short- and long-term monitoring information with management choices to help shape a remediation approach that provides useful information for adaptive, incremental implementation. PMID:25665032

ACHIEVING THE PROMISE OF THERAPEUTIC EXTRACELLULAR VESICLES: THE DEVIL IS IN DETAILS OF THERAPEUTIC LOADING

PubMed Central

Sutaria, Dhruvitkumar S.; Badawi, Mohamed; Phelps, Mitch A.; Schmittgen, Thomas D.

2017-01-01

Extracellular vesicles (EVs) represent a class of cell secreted organelles which naturally contain biomolecular cargo such as miRNA, mRNA and proteins. EVs mediate intercellular communication, enabling the transfer of functional nucleic acids from the cell of origin to the recipient cells. In addition, EVs make an attractive delivery vehicle for therapeutics owing to their increased stability in circulation, biocompatibility, low immunogenicity and toxicity profiles. EVs can also be engineered to display targeting moieties on their surfaces which enables targeting to desired tissues, organs or cells. While much has been learned on the role of EVs as cell communicators, the field of therapeutic EV application is currently under development. Critical to the future success of EV delivery system is the description of methods by which therapeutics can be successfully and efficiently loaded within the EVs. Two methods of loading of EVs with therapeutic cargo exist, endogenous and exogenous loading. We have therefore focused this review on describing the various published approaches for loading EVs with therapeutics. PMID:28315083

Loading direction-dependent shear behavior at different temperatures of single-layer chiral graphene sheets

NASA Astrophysics Data System (ADS)

Zhao, Yang; Dong, Shuhong; Yu, Peishi; Zhao, Junhua

2018-06-01

The loading direction-dependent shear behavior of single-layer chiral graphene sheets at different temperatures is studied by molecular dynamics (MD) simulations. Our results show that the shear properties (such as shear stress-strain curves, buckling strains, and failure strains) of chiral graphene sheets strongly depend on the loading direction due to the structural asymmetry. The maximum values of both the critical buckling shear strain and the failure strain under positive shear deformation can be around 1.4 times higher than those under negative shear deformation. For a given chiral graphene sheet, both its failure strain and failure stress decrease with increasing temperature. In particular, the amplitude to wavelength ratio of wrinkles for different chiral graphene sheets under shear deformation using present MD simulations agrees well with that from the existing theory. These findings provide physical insights into the origins of the loading direction-dependent shear behavior of chiral graphene sheets and their potential applications in nanodevices.

Analysis, testing and verification of the behavior of composite pavements under Florida conditions using a heavy vehicle simulator

NASA Astrophysics Data System (ADS)

Tapia Gutierrez, Patricio Enrique

Whitetopping (WT) is a rehabilitation method to resurface deteriorated asphalt pavements. While some of these composite pavements have performed very well carrying heavy load, other have shown poor performance with early cracking. With the objective of analyzing the applicability of WT pavements under Florida conditions, a total of nine full-scale WT test sections were constructed and tested using a Heavy Vehicle Simulator (HVS) in the APT facility at the FDOT Material Research Park. The test sections were instrumented to monitor both strain and temperature. A 3-D finite element model was developed to analyze the WT test sections. The model was calibrated and verified using measured FWD deflections and HVS load-induced strains from the test sections. The model was then used to evaluate the potential performance of these test sections under critical temperature-load condition in Florida. Six of the WT pavement test sections had a bonded concrete-asphalt interface by milling, cleaning and spraying with water the asphalt surface. This method produced excellent bonding at the interface, with shear strength of 195 to 220 psi. Three of the test sections were intended to have an unbonded concrete-asphalt interface by applying a debonding agent in the asphalt surface. However, shear strengths between 119 and 135 psi and a careful analysis of the strain and the temperature data indicated a partial bond condition. The computer model was able to satisfactorily model the behavior of the composite pavement by mainly considering material properties from standard laboratory tests and calibrating the spring elements used to model the interface. Reasonable matches between the measured and the calculated strains were achieved when a temperature-dependent AC elastic modulus was included in the analytical model. The expected numbers of repetitions of the 24-kip single axle loads at critical thermal condition were computed for the nine test sections based on maximum tensile stresses and fatigue theory. The results showed that 4" slabs can be used for heavy loads only for low-volume traffic. To withstand the critical load without fear of fatigue failure, 6" slabs and 8" slabs would be needed for joint spacings of 4' and 6', respectively.

Fatigue loading and R-curve behavior of a dental glass-ceramic with multiple flaw distributions.

PubMed

Joshi, Gaurav V; Duan, Yuanyuan; Della Bona, Alvaro; Hill, Thomas J; St John, Kenneth; Griggs, Jason A

2013-11-01

To determine the effects of surface finish and mechanical loading on the rising toughness curve (R-curve) behavior of a fluorapatite glass-ceramic (IPS e.max ZirPress) and to determine a statistical model for fitting fatigue lifetime data with multiple flaw distributions. Rectangular beam specimens were fabricated by pressing. Two groups of specimens (n=30) with polished (15 μm) or air abraded surface were tested under rapid monotonic loading in oil. Additional polished specimens were subjected to cyclic loading at 2 Hz (n=44) and 10 Hz (n=36). All fatigue tests were performed using a fully articulated four-point flexure fixture in 37°C water. Fractography was used to determine the critical flaw size and estimate fracture toughness. To prove the presence of R-curve behavior, non-linear regression was used. Forward stepwise regression was performed to determine the effects on fracture toughness of different variables, such as initial flaw type, critical flaw size, critical flaw eccentricity, cycling frequency, peak load, and number of cycles. Fatigue lifetime data were fit to an exclusive flaw model. There was an increase in fracture toughness values with increasing critical flaw size for both loading methods (rapid monotonic loading and fatigue). The values for the fracture toughness ranged from 0.75 to 1.1 MPam(1/2) reaching a plateau at different critical flaw sizes based on loading method. Cyclic loading had a significant effect on the R-curve behavior. The fatigue lifetime distribution was dependent on the flaw distribution, and it fit well to an exclusive flaw model. Copyright © 2013 Academy of Dental Materials. Published by Elsevier Ltd. All rights reserved.

Fatigue loading and R-curve behavior of a dental glass-ceramic with multiple flaw distributions

PubMed Central

Joshi, Gaurav V.; Duan, Yuanyuan; Bona, Alvaro Della; Hill, Thomas J.; John, Kenneth St.; Griggs, Jason A.

2013-01-01

Objectives To determine the effects of surface finish and mechanical loading on the rising toughness curve (R-curve) behavior of a fluorapatite glass-ceramic (IPS e.max ZirPress) and to determine a statistical model for fitting fatigue lifetime data with multiple flaw distributions. Materials and Methods Rectangular beam specimens were fabricated by pressing. Two groups of specimens (n=30) with polished (15 μm) or air abraded surface were tested under rapid monotonic loading in oil. Additional polished specimens were subjected to cyclic loading at 2 Hz (n=44) and 10 Hz (n=36). All fatigue tests were performed using a fully articulated four-point flexure fixture in 37°C water. Fractography was used to determine the critical flaw size and estimate fracture toughness. To prove the presence of R-curve behavior, non-linear regression was used. Forward stepwise regression was performed to determine the effects on fracture toughness of different variables, such as initial flaw type, critical flaw size, critical flaw eccentricity, cycling frequency, peak load, and number of cycles. Fatigue lifetime data were fit to an exclusive flaw model. Results There was an increase in fracture toughness values with increasing critical flaw size for both loading methods (rapid monotonic loading and fatigue). The values for the fracture toughness ranged from 0.75 to 1.1 MPa·m1/2 reaching a plateau at different critical flaw sizes based on loading method. Significance Cyclic loading had a significant effect on the R-curve behavior. The fatigue lifetime distribution was dependent on the flaw distribution, and it fit well to an exclusive flaw model. PMID:24034441

Effects of stressor characteristics on early warning signs of critical transitions and "critical coupling" in complex dynamical systems.

PubMed

Blume, Steffen O P; Sansavini, Giovanni

2017-12-01

Complex dynamical systems face abrupt transitions into unstable and catastrophic regimes. These critical transitions are triggered by gradual modifications in stressors, which push the dynamical system towards unstable regimes. Bifurcation analysis can characterize such critical thresholds, beyond which systems become unstable. Moreover, the stochasticity of the external stressors causes small-scale fluctuations in the system response. In some systems, the decomposition of these signal fluctuations into precursor signals can reveal early warning signs prior to the critical transition. Here, we present a dynamical analysis of a power system subjected to an increasing load level and small-scale stochastic load perturbations. We show that the auto- and cross-correlations of bus voltage magnitudes increase, leading up to a Hopf bifurcation point, and further grow until the system collapses. This evidences a gradual transition into a state of "critical coupling," which is complementary to the established concept of "critical slowing down." Furthermore, we analyze the effects of the type of load perturbation and load characteristics on early warning signs and find that gradient changes in the autocorrelation provide early warning signs of the imminent critical transition under white-noise but not for auto-correlated load perturbations. Furthermore, the cross-correlation between all voltage magnitude pairs generally increases prior to and beyond the Hopf bifurcation point, indicating "critical coupling," but cannot provide early warning indications. Finally, we show that the established early warning indicators are oblivious to limit-induced bifurcations and, in the case of the power system model considered here, only react to an approaching Hopf bifurcation.

Buckling Response of a Large-Scale, Seamless, Orthogrid-Stiffened Metallic Cylinder

NASA Technical Reports Server (NTRS)

Rudd, Michelle Tillotson; Hilburger, Mark W.; Lovejoy, Andrew E.; Lindell, Michael C.; Gardner, Nathaniel W.; Schultz, Marc R.

2018-01-01

Results from the buckling test of a compression-loaded 8-ft-diameter seamless (i.e., without manufacturing joints), orthogrid-stiffened metallic cylinder are presented. This test was used to assess the buckling response and imperfection sensitivity characteristics of a seamless cylinder. In addition, the test article and test served as a technology demonstration to show the application of the flow forming manufacturing process to build more efficient buckling-critical structures by eliminating the welded joints that are traditionally used in the manufacturing of large metallic barrels. Pretest predictions of the cylinder buckling response were obtained using a finite-element model that included measured geometric imperfections. The buckling load predicted using this model was 697,000 lb, and the test article buckled at 743,000 lb (6% higher). After the test, the model was revised to account for measured variations in skin and stiffener geometry, nonuniform loading, and material properties. The revised model predicted a buckling load of 754,000 lb, which is within 1.5% of the tested buckling load. In addition, it was determined that the load carrying capability of the seamless cylinder is approximately 28% greater than a corresponding cylinder with welded joints.

Damage accumulation in titanium matrix composites under generic hypersonic vehicle flight simulation and sustained loads

DOE Office of Scientific and Technical Information (OSTI.GOV)

Johnson, W.S.; Mirdamadi, M.; Bakuckas, J.G. Jr.

1996-12-31

Titanium matrix composites (TMC), such as Ti-15V-3Cr-3Al-3Sn (Ti-15-3) reinforced with continuous silicon-carbide fibers (SCS-6), are being evaluated for use in hypersonic vehicles and advanced gas turbine engines where high strength-to-weight and high stiffness-to-weight ratios at elevated temperatures are critical. Such applications expose the composite to mechanical fatigue loading as well as thermally induced cycles. The damage accumulation behavior of a [0/90]2s laminate made of Ti-15V-3Cr-3Al-3Sn (Ti-15-3) reinforced with continuous silicon-carbide fibers (SCS-6) subjected to a simulated generic hypersonic flight profile, portions of the flight profile, and sustained loads was evaluated experimentally. Portions of the flight profile were used separately tomore » isolate combinations of load and time at temperature that influenced the fatigue behavior of the composite. Sustained load tests were also conducted and the results were compared with the fatigue results under the flight profile and its portions. The test results indicated that the fatigue strength of this materials system is considerably reduced by a combination of load and time at temperature.« less

Mechanical annealing under low-amplitude cyclic loading in micropillars

NASA Astrophysics Data System (ADS)

Cui, Yi-nan; Liu, Zhan-li; Wang, Zhang-jie; Zhuang, Zhuo

2016-04-01

Mechanical annealing has been demonstrated to be an effective method for decreasing the overall dislocation density in submicron single crystal. However, simultaneously significant shape change always unexpectedly happens under extremely high monotonic loading to drive the pre-existing dislocations out of the free surfaces. In the present work, through in situ TEM experiments it is found that cyclic loading with low stress amplitude can drive most dislocations out of the submicron sample with virtually little change of the shape. The underlying dislocation mechanism is revealed by carrying out discrete dislocation dynamic (DDD) simulations. The simulation results indicate that the dislocation density decreases within cycles, while the accumulated plastic strain is small. By comparing the evolution of dislocation junction under monotonic, cyclic and relaxation deformation, the cumulative irreversible slip is found to be the key factor of promoting junction destruction and dislocation annihilation at free surface under low-amplitude cyclic loading condition. By introducing this mechanics into dislocation density evolution equations, the critical conditions for mechanical annealing under cyclic and monotonic loadings are discussed. Low-amplitude cyclic loading which strengthens the single crystal without seriously disturbing the structure has the potential applications in the manufacture of defect-free nano-devices.

A survey on investigating the need for intelligent power-aware load balanced routing protocols for handling critical links in MANETs.

PubMed

Sivakumar, B; Bhalaji, N; Sivakumar, D

2014-01-01

In mobile ad hoc networks connectivity is always an issue of concern. Due to dynamism in the behavior of mobile nodes, efficiency shall be achieved only with the assumption of good network infrastructure. Presence of critical links results in deterioration which should be detected in advance to retain the prevailing communication setup. This paper discusses a short survey on the specialized algorithms and protocols related to energy efficient load balancing for critical link detection in the recent literature. This paper also suggests a machine learning based hybrid power-aware approach for handling critical nodes via load balancing.

A Survey on Investigating the Need for Intelligent Power-Aware Load Balanced Routing Protocols for Handling Critical Links in MANETs

PubMed Central

Sivakumar, B.; Bhalaji, N.; Sivakumar, D.

2014-01-01

In mobile ad hoc networks connectivity is always an issue of concern. Due to dynamism in the behavior of mobile nodes, efficiency shall be achieved only with the assumption of good network infrastructure. Presence of critical links results in deterioration which should be detected in advance to retain the prevailing communication setup. This paper discusses a short survey on the specialized algorithms and protocols related to energy efficient load balancing for critical link detection in the recent literature. This paper also suggests a machine learning based hybrid power-aware approach for handling critical nodes via load balancing. PMID:24790546

Potential nitrogen critical loads for northern Great Plains grassland vegetation

USGS Publications Warehouse

Symstad, Amy J.; Smith, Anine T.; Newton, Wesley E.; Knapp, Alan K.

2015-01-01

The National Park Service is concerned that increasing atmospheric nitrogen deposition caused by fossil fuel combustion and agricultural activities could adversely affect the northern Great Plains (NGP) ecosystems in its trust. The critical load concept facilitates communication between scientists and policy makers or land managers by translating the complex effects of air pollution on ecosystems into concrete numbers that can be used to inform air quality targets. A critical load is the exposure level below which significant harmful effects on sensitive elements of the environment do not occur. A recent review of the literature suggested that the nitrogen critical load for Great Plains vegetation is 10-25 kg N/ha/yr. For comparison, current atmospheric nitrogen deposition in NGP National Park Service (NPS) units ranges from ~4 kg N/ha/yr in the west to ~13 kg N/ha/yr in the east. The suggested critical load, however, was derived from studies far outside of the NGP, and from experiments investigating nitrogen loads substantially higher than current atmospheric deposition in the region.Therefore, to better determine the nitrogen critical load for sensitive elements in NGP parks, we conducted a four-year field experiment in three northern Great Plains vegetation types at Badlands and Wind Cave National Parks. The vegetation types were chosen because of their importance in NGP parks, their expected sensitivity to nitrogen addition, and to span a range of natural fertility. In the experiment, we added nitrogen at rates ranging from below current atmospheric deposition (2.5 kg N/ha/yr) to far above those levels but commensurate with earlier experiments (100 kg N/ha/yr). We measured the response of a variety of vegetation and soil characteristics shown to be sensitive to nitrogen addition in other studies, including plant biomass production, plant tissue nitrogen concentration, plant species richness and composition, non-native species abundance, and soil inorganic nitrogen concentration. To determine critical loads for the NGP plant communities in our experiment, we followed the NPS’s precautionary principle in assuming that it is better to be cautious than to let harm occur to the environment. Thus, the critical loads we derived are the lowest nitrogen level that any of our data suggest has a measureable effect on any of the response variables measured.Badlands sparse vegetation, a low-productivity plant community that is an important part of the scenery at Badlands National Park and provides habitat for rare plant species, was the most sensitive of the three vegetation types. More aspects of this vegetation type responded to nitrogen addition, and at lower levels, than at the other two sites. Our data suggest that nitrogen deposition levels of 4- 6 kg N/ha/yr may increase biomass production, and consequently the amount of dead plant material on the ground in this plant community. Slightly higher critical loads are suggested for the two more productive vegetation types more characteristic of most NGP grasslands: 6-10 kg N/ha/yr for biomass production, grass tissue nitrogen concentration, or non-native species (especially annual brome grasses) cover. Highly variable results among years, as well as inconsistent responses to an increasing dose of nitrogen within sites, complicated the derivation of critical loads in this experiment, however. A less precautionary approach to deriving critical loads yielded higher values of 10-38 kg N/ha/yr.

Optimal periodic proof test based on cost-effective and reliability criteria

NASA Technical Reports Server (NTRS)

Yang, J.-N.

1976-01-01

An exploratory study for the optimization of periodic proof tests for fatigue-critical structures is presented. The optimal proof load level and the optimal number of periodic proof tests are determined by minimizing the total expected (statistical average) cost, while the constraint on the allowable level of structural reliability is satisfied. The total expected cost consists of the expected cost of proof tests, the expected cost of structures destroyed by proof tests, and the expected cost of structural failure in service. It is demonstrated by numerical examples that significant cost saving and reliability improvement for fatigue-critical structures can be achieved by the application of the optimal periodic proof test. The present study is relevant to the establishment of optimal maintenance procedures for fatigue-critical structures.

In-vitro development of a temporal abutment screw to protect osseointegration in immediate loaded implants

PubMed Central

2015-01-01

PURPOSE In this study, a temporal abutment fixation screw, designed to fracture in a controlled way upon application of an occlusal force sufficient to produce critical micromotion was developed. The purpose of the screw was to protect the osseointegration of immediate loaded single implants. MATERIALS AND METHODS Seven different screw prototypes were examined by fixing titanium abutments to 112 Mozo-Grau external hexagon implants (MG Osseous®; Mozo-Grau, S.A., Valladolid, Spain). Fracture strength was tested at 30° in two subgroups per screw: one under dynamic loading and the other without prior dynamic loading. Dynamic loading was performed in a single-axis chewing simulator using 150,000 load cycles at 50 N. After normal distribution of obtained data was verified by Kolmogorov-Smirnov test, fracture resistance between samples submitted and not submitted to dynamic loading was compared by the use of Student's t-test. Comparison of fracture resistance among different screw designs was performed by the use of one-way analysis of variance. Confidence interval was set at 95%. RESULTS Fractures occurred in all screws, allowing easy retrieval. Screw Prototypes 2, 5 and 6 failed during dynamic loading and exhibited statistically significant differences from the other prototypes. CONCLUSION Prototypes 2, 5 and 6 may offer a useful protective mechanism during occlusal overload in immediate loaded implants. PMID:25932315

Rating curve estimation of nutrient loads in Iowa rivers

USGS Publications Warehouse

Stenback, G.A.; Crumpton, W.G.; Schilling, K.E.; Helmers, M.J.

2011-01-01

Accurate estimation of nutrient loads in rivers and streams is critical for many applications including determination of sources of nutrient loads in watersheds, evaluating long-term trends in loads, and estimating loading to downstream waterbodies. Since in many cases nutrient concentrations are measured on a weekly or monthly frequency, there is a need to estimate concentration and loads during periods when no data is available. The objectives of this study were to: (i) document the performance of a multiple regression model to predict loads of nitrate and total phosphorus (TP) in Iowa rivers and streams; (ii) determine whether there is any systematic bias in the load prediction estimates for nitrate and TP; and (iii) evaluate streamflow and concentration factors that could affect the load prediction efficiency. A commonly cited rating curve regression is utilized to estimate riverine nitrate and TP loads for rivers in Iowa with watershed areas ranging from 17.4 to over 34,600km2. Forty-nine nitrate and 44 TP datasets each comprising 5-22years of approximately weekly to monthly concentrations were examined. Three nitrate data sets had sample collection frequencies averaging about three samples per week. The accuracy and precision of annual and long term riverine load prediction was assessed by direct comparison of rating curve load predictions with observed daily loads. Significant positive bias of annual and long term nitrate loads was detected. Long term rating curve nitrate load predictions exceeded observed loads by 25% or more at 33% of the 49 measurement sites. No bias was found for TP load prediction although 15% of the 44 cases either underestimated or overestimate observed long-term loads by more than 25%. The rating curve was found to poorly characterize nitrate and phosphorus variation in some rivers. ?? 2010 .

Characterization and investigation of the deformation behavior of porous magnesium scaffolds with entangled architectured pore channels.

PubMed

Jiang, Guofeng; Li, Qiuyan; Wang, Cunlong; Dong, Jie; He, Guo

2016-12-01

We report a kind of porous magnesium with entangled architectured pore structure for potential applications in biomedical implant. The pore size, spatial structure and Young׳s modulus of the as-prepared porous Mg are suitable for bone tissue engineering applications. Particularly, with regard to the load-bearing conditions, a new analytical model is employed to investigate its structure and mechanical response under compressive stress based on Gibson-Ashby model. It is found that there are three types of stress-strain behaviors in the large range of porosity from 20% to 80%. When the porosity is larger than an upper critical value, the porous magnesium exhibits densifying behavior with buckling deformation mechanism. When the porosity is smaller than a lower critical value, the porous magnesium exhibits shearing behavior with cracking along the maximum shear stress. Between the two critical porosities, both the buckling deformation and shearing behavior coexist. The upper critical porosity is experimentally determined to be 60% for 270μm pore size and 62% for 400μm pore size, while the lower critical porosity is 40% for 270μm pore size and 42% for 400μm pore size. A new analytical model could be used to accurately predict the mechanical response of the porous magnesium. No matter the calculated critical porosity or yielding stress in a large range of porosity by using the new model are well consistent with the experimental values. All these results could help to provide valuable data for developing the present porous magnesium for potential bio applications. Copyright © 2016 Elsevier Ltd. All rights reserved.

Determination of the critical plane and durability estimation for a multiaxial cyclic loading

NASA Astrophysics Data System (ADS)

Burago, N. G.; Nikitin, A. D.; Nikitin, I. S.; Yakushev, V. L.

2018-03-01

An analytical procedure is proposed to determine the critical plane orientation according to the Findley criterion for the multiaxial cyclic loading. The cases of in-phase and anti-phase cyclic loading are considered. Calculations of the stress state are carried out for the system of the gas turbine engine compressor disk and blades for flight loading cycles. The formulas obtained are used for estimations of the fatigue durability of this essential element of structure.

Effect of Assumed Damage and Location on the Delamination Onset Predictions for Skin-Stiffener Debonding

NASA Technical Reports Server (NTRS)

Paris, Isabelle L.; Krueger, Ronald; OBrien, T. Kevin

2004-01-01

The difference in delamination onset predictions based on the type and location of the assumed initial damage are compared in a specimen consisting of a tapered flange laminate bonded to a skin laminate. From previous experimental work, the damage was identified to consist of a matrix crack in the top skin layer followed by a delamination between the top and second skin layer (+45 deg./-45 deg. interface). Two-dimensional finite elements analyses were performed for three different assumed flaws and the results show a considerable reduction in critical load if an initial delamination is assumed to be present, both under tension and bending loads. For a crack length corresponding to the peak in the strain energy release rate, the delamination onset load for an assumed initial flaw in the bondline is slightly higher than the critical load for delamination onset from an assumed skin matrix crack, both under tension and bending loads. As a result, assuming an initial flaw in the bondline is simpler while providing a critical load relatively close to the real case. For the configuration studied, a small delamination might form at a lower tension load than the critical load calculated for a 12.7 mm (0.5") delamination, but it would grow in a stable manner. For the bending case, assuming an initial flaw of 12.7 mm (0.5") is conservative, the crack would grow unstably.

Adhesion scratch testing - A round-robin experiment

NASA Technical Reports Server (NTRS)

Perry, A. J.; Valli, J.; Steinmann, P. A.

1988-01-01

Six sets of samples, TiN coated by chemical or physical vapor deposition methods (CVD or PVD) onto cemented carbide or high-speed steel (HSS), and TiC coated by CVD onto cemented carbide have been scratch tested using three types of commercially available scratch adhesion tester. With exception of one cemented carbide set, the reproducibility of the critical loads for any given set with a given stylus is excellent, about + or - 5 percent, and is about + or - 20 percent for different styli. Any differences in critical loads recorded for any given sample set can be attributed to the condition of the stylus (clean, new, etc.), the instrument used, the stylus itself (friction coefficient, etc.), and the sample set itself. One CVD set showed remarkably large differences in critical loads for different styli, which is thought to be related to a mechanical interaction between stylus and coating which is enhanced by a plastic deformability in the film related to the coating microstructure. The critical load for TiN on HSS increases with coating thickness, and differences in frictional conditions led to a systematic variation in the critical loads depending on the stylus used.

Shock enhancement of cellular materials subjected to intensive pulse loading

NASA Astrophysics Data System (ADS)

Zhang, J.; Fan, J.; Wang, Z.; Zhao, L.; Li, Z.

2018-03-01

Cellular materials can dissipate a large amount of energy due to their considerable stress plateau, which contributes to their extensive applications in structural design for crashworthiness. However, in some experiments with specimens subjected to intense impact loads, transmitted stress enhancement has been observed, leading to severe damage to the objects protected. Transmitted stress through two-dimensional Voronoi cellular materials as a protective device is qualitatively studied in this paper. Dimensionless parameters of material properties and loading parameters are defined to give critical conditions for shock enhancement and clarify the correlation between the deformations and stress enhancement. The effect of relative density on this amplifying phenomenon is investigated as well. In addition, local strain fields are calculated by using the optimal local deformation gradient, which gives a clear presentation of deformations and possible local non-uniformity in the crushing process. This research provides valuable insight into the reliability of cellular materials as protective structures.

Brittle materials at high-loading rates: an open area of research

NASA Astrophysics Data System (ADS)

Forquin, Pascal

2017-01-01

Brittle materials are extensively used in many civil and military applications involving high-strain-rate loadings such as: blasting or percussive drilling of rocks, ballistic impact against ceramic armour or transparent windshields, plastic explosives used to damage or destroy concrete structures, soft or hard impacts against concrete structures and so on. With all of these applications, brittle materials are subjected to intense loadings characterized by medium to extremely high strain rates (few tens to several tens of thousands per second) leading to extreme and/or specific damage modes such as multiple fragmentation, dynamic cracking, pore collapse, shearing, mode II fracturing and/or microplasticity mechanisms in the material. Additionally, brittle materials exhibit complex features such as a strong strain-rate sensitivity and confining pressure sensitivity that justify expending greater research efforts to understand these complex features. Currently, the most popular dynamic testing techniques used for this are based on the use of split Hopkinson pressure bar methodologies and/or plate-impact testing methods. However, these methods do have some critical limitations and drawbacks when used to investigate the behaviour of brittle materials at high loading rates. The present theme issue of Philosophical Transactions A provides an overview of the latest experimental methods and numerical tools that are currently being developed to investigate the behaviour of brittle materials at high loading rates. This article is part of the themed issue 'Experimental testing and modelling of brittle materials at high strain rates'.

Brittle materials at high-loading rates: an open area of research

PubMed Central

2017-01-01

Brittle materials are extensively used in many civil and military applications involving high-strain-rate loadings such as: blasting or percussive drilling of rocks, ballistic impact against ceramic armour or transparent windshields, plastic explosives used to damage or destroy concrete structures, soft or hard impacts against concrete structures and so on. With all of these applications, brittle materials are subjected to intense loadings characterized by medium to extremely high strain rates (few tens to several tens of thousands per second) leading to extreme and/or specific damage modes such as multiple fragmentation, dynamic cracking, pore collapse, shearing, mode II fracturing and/or microplasticity mechanisms in the material. Additionally, brittle materials exhibit complex features such as a strong strain-rate sensitivity and confining pressure sensitivity that justify expending greater research efforts to understand these complex features. Currently, the most popular dynamic testing techniques used for this are based on the use of split Hopkinson pressure bar methodologies and/or plate-impact testing methods. However, these methods do have some critical limitations and drawbacks when used to investigate the behaviour of brittle materials at high loading rates. The present theme issue of Philosophical Transactions A provides an overview of the latest experimental methods and numerical tools that are currently being developed to investigate the behaviour of brittle materials at high loading rates. This article is part of the themed issue ‘Experimental testing and modelling of brittle materials at high strain rates’. PMID:27956517

Brittle materials at high-loading rates: an open area of research.

PubMed

Forquin, Pascal

2017-01-28

Brittle materials are extensively used in many civil and military applications involving high-strain-rate loadings such as: blasting or percussive drilling of rocks, ballistic impact against ceramic armour or transparent windshields, plastic explosives used to damage or destroy concrete structures, soft or hard impacts against concrete structures and so on. With all of these applications, brittle materials are subjected to intense loadings characterized by medium to extremely high strain rates (few tens to several tens of thousands per second) leading to extreme and/or specific damage modes such as multiple fragmentation, dynamic cracking, pore collapse, shearing, mode II fracturing and/or microplasticity mechanisms in the material. Additionally, brittle materials exhibit complex features such as a strong strain-rate sensitivity and confining pressure sensitivity that justify expending greater research efforts to understand these complex features. Currently, the most popular dynamic testing techniques used for this are based on the use of split Hopkinson pressure bar methodologies and/or plate-impact testing methods. However, these methods do have some critical limitations and drawbacks when used to investigate the behaviour of brittle materials at high loading rates. The present theme issue of Philosophical Transactions A provides an overview of the latest experimental methods and numerical tools that are currently being developed to investigate the behaviour of brittle materials at high loading rates.This article is part of the themed issue 'Experimental testing and modelling of brittle materials at high strain rates'. © 2016 The Author(s).

Buckling of Thermoviscoelastic Structures Under Temporal and Spatial Temperature Variations

NASA Technical Reports Server (NTRS)

Tsuyuki, Richard; Knauss, Wolfgang G.

1992-01-01

The problem of lateral instability of a viscoelastic in-plane loaded structure is considered in terms of thermorheolgically simple materials. As an example of a generally in-plane loaded structure, we examine the simple column under axial load: Both cyclic loading is considered (with constant or in-phase variable temperature excursions) as well as the case of constant load in the presence of thermal gradients through the thickness of the structure. The latter case involves a continuous movement of the neutral axis from the center to the colder side and then back to the center. In both cases, temperature has a very strong effect on the instability evolution, and under in-phase thermal cycling the critical loads are reduced compared to those at constant temperatures. The primary effect of thermal gradients beyond that of thermally-induced rate accelerations is occasioned by the generation of an "initial imperfection" or "structural bowing." Because the coefficient of thermal expansion tends to be large for many polymeric materials, it it may be necessary to take special care in lay-up design of composite structures intended for use under compressive loads in high-temperature applications. Finally, the implications for the temperature sensitivities of composites to micro-instability (fiber crimping) are also apparent from the results delineated here.

Impact of sampling strategy on stream load estimates in till landscape of the Midwest

USGS Publications Warehouse

Vidon, P.; Hubbard, L.E.; Soyeux, E.

2009-01-01

Accurately estimating various solute loads in streams during storms is critical to accurately determine maximum daily loads for regulatory purposes. This study investigates the impact of sampling strategy on solute load estimates in streams in the US Midwest. Three different solute types (nitrate, magnesium, and dissolved organic carbon (DOC)) and three sampling strategies are assessed. Regardless of the method, the average error on nitrate loads is higher than for magnesium or DOC loads, and all three methods generally underestimate DOC loads and overestimate magnesium loads. Increasing sampling frequency only slightly improves the accuracy of solute load estimates but generally improves the precision of load calculations. This type of investigation is critical for water management and environmental assessment so error on solute load calculations can be taken into account by landscape managers, and sampling strategies optimized as a function of monitoring objectives. ?? 2008 Springer Science+Business Media B.V.

Developments in steady and unsteady aerodynamics for use in aeroelastic analysis and design. [for supersonic cruise aircraft

NASA Technical Reports Server (NTRS)

Yates, E. C., Jr.; Bland, S. R.

1976-01-01

A review is given of seven research projects which are aimed at improving the generality, accuracy, and computational efficiency of steady and unsteady aerodynamic theory for use in aeroelastic analysis and design. These projects indicate three major thrusts of current research efforts: (1) more realistic representation of steady and unsteady subsonic and supersonic loads on aircraft configurations of general shape with emphasis on structural-design applications, (2) unsteady aerodynamics for application in active-controls analyses, and (3) unsteady aerodynamics for the frequently critical transonic speed range. The review of each project includes theoretical background, description of capabilities, results of application, current status, and plans for further development and use.

Understanding Irreversible Degradation of Nb3Sn Wires with Fundamental Fracture Mechanics

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhai, Yuhu; Calzolaio, Ciro; Senatore, Carmine

2014-08-01

Irreversible performance degradation of advanced Nb3Sn superconducting wires subjected to transverse or axial mechanical loading is a critical issue for the design of large-scale fusion and accelerator magnets such as ITER and LHC. Recent SULTAN tests indicate that most cable-in-conduit conductors for ITER coils made of Nb3Sn wires processed by various fabrication techniques show similar performance degradation under cyclic loading. The irreversible degradation due to filament fracture and local strain accumulation in Nb3Sn wires cannot be described by the existing strand scaling law. Fracture mechanic modeling combined with X-ray diffraction imaging of filament micro-crack formation inside the wires under mechanicalmore » loading may reveal exciting insights to the wire degradation mechanisms. We apply fundamental fracture mechanics with a singularity approach to study influence of wire filament microstructure of initial void size and distribution to local stress concentration and potential crack propagation. We report impact of the scale and density of the void structure on stress concentration in the composite wire materials for crack initiation. These initial defects result in an irreversible degradation of the critical current beyond certain applied stress. We also discuss options to minimize stress concentration in the design of the material microstructure for enhanced wire performance for future applications.« less

Flexural edge waves generated by steady-state propagation of a loaded rectilinear crack in an elastically supported thin plate

NASA Astrophysics Data System (ADS)

Nobili, Andrea; Radi, Enrico; Lanzoni, Luca

2017-08-01

The problem of a rectilinear crack propagating at constant speed in an elastically supported thin plate and acted upon by an equally moving load is considered. The full-field solution is obtained and the spotlight is set on flexural edge wave generation. Below the critical speed for the appearance of travelling waves, a threshold speed is met which marks the transformation of decaying edge waves into edge waves propagating along the crack and dying away from it. Yet, besides these, and for any propagation speed, a pair of localized edge waves, which rapidly decay behind the crack tip, is also shown to exist. These waves are characterized by a novel dispersion relation and fade off from the crack line in an oscillatory manner, whence they play an important role in the far field behaviour. Dynamic stress intensity factors are obtained and, for speed close to the critical speed, they show a resonant behaviour which expresses the most efficient way to channel external work into the crack. Indeed, this behaviour is justified through energy considerations regarding the work of the applied load and the energy release rate. Results might be useful in a wide array of applications, ranging from fracturing and machining to acoustic emission and defect detection.

Flexural edge waves generated by steady-state propagation of a loaded rectilinear crack in an elastically supported thin plate.

PubMed

Nobili, Andrea; Radi, Enrico; Lanzoni, Luca

2017-08-01

The problem of a rectilinear crack propagating at constant speed in an elastically supported thin plate and acted upon by an equally moving load is considered. The full-field solution is obtained and the spotlight is set on flexural edge wave generation. Below the critical speed for the appearance of travelling waves, a threshold speed is met which marks the transformation of decaying edge waves into edge waves propagating along the crack and dying away from it. Yet, besides these, and for any propagation speed, a pair of localized edge waves, which rapidly decay behind the crack tip, is also shown to exist. These waves are characterized by a novel dispersion relation and fade off from the crack line in an oscillatory manner, whence they play an important role in the far field behaviour. Dynamic stress intensity factors are obtained and, for speed close to the critical speed, they show a resonant behaviour which expresses the most efficient way to channel external work into the crack. Indeed, this behaviour is justified through energy considerations regarding the work of the applied load and the energy release rate. Results might be useful in a wide array of applications, ranging from fracturing and machining to acoustic emission and defect detection.

Perceptual load in different regions of the visual scene and its relevance for driving.

PubMed

Marciano, Hadas; Yeshurun, Yaffa

2015-06-01

The aim of this study was to better understand the role played by perceptual load, at both central and peripheral regions of the visual scene, in driving safety. Attention is a crucial factor in driving safety, and previous laboratory studies suggest that perceptual load is an important factor determining the efficiency of attentional selectivity. Yet, the effects of perceptual load on driving were never studied systematically. Using a driving simulator, we orthogonally manipulated the load levels at the road (central load) and its sides (peripheral load), while occasionally introducing critical events at one of these regions. Perceptual load affected driving performance at both regions of the visual scene. Critically, the effect was different for central versus peripheral load: Whereas load levels on the road mainly affected driving speed, load levels on its sides mainly affected the ability to detect critical events initiating from the roadsides. Moreover, higher levels of peripheral load impaired performance but mainly with low levels of central load, replicating findings with simple letter stimuli. Perceptual load has a considerable effect on driving, but the nature of this effect depends on the region of the visual scene at which the load is introduced. Given the observed importance of perceptual load, authors of future studies of driving safety should take it into account. Specifically, these findings suggest that our understanding of factors that may be relevant for driving safety would benefit from studying these factors under different levels of load at different regions of the visual scene. © 2014, Human Factors and Ergonomics Society.

A Submersible Holographic Camera for the Undisturbed Characterization of Optically Relevant Particles in Water (HOLOCAM)

DTIC Science & Technology

2012-09-01

how to improve both reconstruction and analytical software during testing of the submersible system. IMPACT AND APPLICATIONS Quality of Life...project (see related projects below). It could also be used for sediment load monitoring and assesment . The HOLOCAM could provide critical data to any...Science Education and Communication Currently the link between the suspended particle field and the bulk scattering properties of natural waters is

Direct writing of bio-functional coatings for cardiovascular applications.

PubMed

Perkins, Jessica; Hong, Yi; Ye, Sang-Ho; Wagner, William R; Desai, Salil

2014-12-01

The surface modification of metallic biomaterials is of critical importance to enhance the biocompatibility of surgical implant materials and devices. This article investigates the use of a direct-write inkjet technique for multilayer coatings of a biodegradable polymer (polyester urethane urea (PEUU)) embedded with an anti-proliferation drug paclitaxel (Taxol). The direct-write inkjet technique provides selective patterning capability for depositing multimaterial coatings on three-dimensional implant devices such as pins, screws, and stents for orthopedic and vascular applications. Drug release profiles were studied to observe the influence of drug loading and coating thickness for obtaining tunable release kinetics. Platelet deposition studies were conducted following ovine blood contact and significant reduction in platelet deposition was observed on the Taxol loaded PEUU substrate compared with the unloaded control. Rat smooth muscle cells were used for cell proliferation studies. Significant reduction in cell growth was observed following the release of anti-proliferative drug from the biopolymer thin film. This research provides a basis for developing anti-proliferative biocompatible coatings for different biomedical device applications. © 2014 Wiley Periodicals, Inc.

Has your ancient stamp been regummed with synthetic glue? A FT-NIR and FT-Raman study.

PubMed

Simonetti, Remo; Oliveri, Paolo; Henry, Adrien; Duponchel, Ludovic; Lanteri, Silvia

2016-01-01

The potential of FT-NIR and FT-Raman spectroscopies to characterise the gum applied on the backside of ancient stamps was investigated for the first time. This represents a very critical issue for the collectors' market, since gum conditions heavily influence stamp quotations, and fraudulent application of synthetic gum onto damaged stamp backsides to increase their desirability is a well-documented practice. Spectral data were processed by exploratory pattern recognition tools. In particular, application of principal component analysis (PCA) revealed that both of the spectroscopic techniques provide information useful to characterise stamp gum. Examination of PCA loadings and their chemical interpretation confirmed the robustness of the outcomes. Fusion of FT-NIR and FT-Raman spectral data was performed, following both a low-level and a mid-level procedure. The results were critically compared with those obtained separately for the two spectroscopic techniques. Copyright © 2015 Elsevier B.V. All rights reserved.

Deposition, Chapter 3

Treesearch

K.C. Weathers; J.A. Lynch

2011-01-01

To determine the effects of air pollution on ecological systems using the critical load approach, accurate estimates of total nitrogen (N) deposition are essential. Empirical critical loads are set by relating observed ecosystem responses to N deposition (measured, experimentally manipulated, or modeled).

Designing pinhole vacancies in graphene towards functionalization: Effects on critical buckling load

NASA Astrophysics Data System (ADS)

Georgantzinos, S. K.; Markolefas, S.; Giannopoulos, G. I.; Katsareas, D. E.; Anifantis, N. K.

2017-03-01

The effect of size and placement of pinhole-type atom vacancies on Euler's critical load on free-standing, monolayer graphene, is investigated. The graphene is modeled by a structural spring-based finite element approach, in which every interatomic interaction is approached as a linear spring. The geometry of graphene and the pinhole size lead to the assembly of the stiffness matrix of the nanostructure. Definition of the boundary conditions of the problem leads to the solution of the eigenvalue problem and consequently to the critical buckling load. Comparison to results found in the literature illustrates the validity and accuracy of the proposed method. Parametric analysis regarding the placement and size of the pinhole-type vacancy, as well as the graphene geometry, depicts the effects on critical buckling load. Non-linear regression analysis leads to empirical-analytical equations for predicting the buckling behavior of graphene, with engineered pinhole-type atom vacancies.

Evaluation of Cask Drop Criticality Issues at K Basin

DOE Office of Scientific and Technical Information (OSTI.GOV)

GOLDMANN, L.H.

An analysis of ability of Multi-canister Overpack (MCO) to withstand drops at K Basin without exceeding the criticality design requirements. Report concludes the MCO will function acceptably. The spent fuel currently residing in the 105 KE and 105 KW storage basins will be placed in fuel storage baskets which will be loaded into the MCO cask assembly. During the basket loading operations the MCO cask assembly will be positioned near the bottom of the south load out pit (SLOP). The loaded MCO cask will be lifted from the SLOP transferred to the transport trailer and delivered to the Cold Vacuummore » Drying Facility (CVDF). In the wet condition there is a potential for criticality problems if significant changes in the designed fuel configurations occur. The purpose of this report is to address structural issues associated with criticality design features for MCO cask drop accidents in the 105 KE and 105 KW facilities.« less

Strength analysis of piezoceramic materials for structural considerations in energy harvesting for UAVs

NASA Astrophysics Data System (ADS)

Anton, S. R.; Erturk, A.; Inman, D. J.

2010-04-01

Vibration energy harvesting has received considerable attention in the research community over the past decade. Typical vibration harvesting systems are designed to be added on to existing host structures and capture ambient vibration energy. An interesting application of vibration energy harvesting exists in unmanned aerial vehicles (UAVs), where a multifunctional approach, as opposed to the traditional method, is needed due to weight and aerodynamic considerations. The authors propose a multifunctional design for energy harvesting in UAVs where the piezoelectric harvesting device is integrated into the wing of a UAV and provides energy harvesting, energy storage, and load bearing capability. The brittle piezoceramic layer of the harvester is a critical member in load bearing applications; therefore, it is the goal of this research to investigate the bending strength of various common piezoceramic materials. Three-point bend tests are carried out on several piezoelectric ceramics including monolithic piezoceramics PZT-5A and PZT-5H, single crystal piezoelectric PMN-PZT, and commercially packaged QuickPack devices. Bending strength results are reported and can be used as a design tool in the development of piezoelectric vibration energy harvesting systems in which the active device is subjected to bending loads.

Analysis on Reactor Criticality Condition and Fuel Conversion Capability Based on Different Loaded Plutonium Composition in FBR Core

NASA Astrophysics Data System (ADS)

Permana, Sidik; Saputra, Geby; Suzuki, Mitsutoshi; Saito, Masaki

2017-01-01

Reactor criticality condition and fuel conversion capability are depending on the fuel arrangement schemes, reactor core geometry and fuel burnup process as well as the effect of different fuel cycle and fuel composition. Criticality condition of reactor core and breeding ratio capability have been investigated in this present study based on fast breeder reactor (FBR) type for different loaded fuel compositions of plutonium in the fuel core regions. Loaded fuel of Plutonium compositions are based on spent nuclear fuel (SNF) of light water reactor (LWR) for different fuel burnup process and cooling time conditions of the reactors. Obtained results show that different initial fuels of plutonium gives a significant chance in criticality conditions and fuel conversion capability. Loaded plutonium based on higher burnup process gives a reduction value of criticality condition or less excess reactivity. It also obtains more fuel breeding ratio capability or more breeding gain. Some loaded plutonium based on longer cooling time of LWR gives less excess reactivity and in the same time, it gives higher breeding ratio capability of the reactors. More composition of even mass plutonium isotopes gives more absorption neutron which affects to decresing criticality or less excess reactivity in the core. Similar condition that more absorption neutron by fertile material or even mass plutonium will produce more fissile material or odd mass plutonium isotopes to increase the breeding gain of the reactor.

Inland surface waters

EPA Science Inventory

A critical load is a “quantitative estimate of the exposure to one or more pollutants below which significant harmful effects on specified sensitive elements of the environment do not occur according to present knowledge”. Critical loads can be either modeled, or calculated empi...

Buckling and Post-Buckling Behaviors of a Variable Stiffness Composite Laminated Wing Box Structure

NASA Astrophysics Data System (ADS)

Wang, Peiyan; Huang, Xinting; Wang, Zhongnan; Geng, Xiaoliang; Wang, Yuansheng

2018-04-01

The buckling and post-buckling behaviors of variable stiffness composite laminates (VSCL) with curvilinear fibers were investigated and compared with constant stiffness composite laminates (CSCL) with straight fibers. A VSCL box structure was evaluated under a pure bending moment. The results of the comparative test showed that the critical buckling load of the VSCL box was approximately 3% higher than that of the CSCL box. However, the post-buckling load-bearing capacity was similar due to the layup angle and the immature status of the material processing technology. The properties of the VSCL and CSCL boxes under a pure bending moment were simulated using the Hashin criterion and cohesive interface elements. The simulation results are consistent with the experimental results in stiffness, critical buckling load and failure modes but not in post-buckling load capacity. The results of the experiment, the simulation and laminated plate theory show that VSCL greatly improves the critical buckling load but has little influence on the post-buckling load-bearing capacity.

Effects of nitrogen deposition and empirical nitrogen critical loads for ecoregions of the United States

USGS Publications Warehouse

Pardo, L.H.; Fenn, M.E.; Goodale, C.L.; Geiser, L.H.; Driscoll, C.T.; Allen, E.B.; Baron, Jill S.; Bobbink, R.; Bowman, W.D.; Clark, C.M.; Emmett, B.; Gilliam, F.S.; Greaver, T.L.; Hall, S.J.; Lilleskov, E.A.; Liu, L.; Lynch, J.A.; Nadelhoffer, K.J.; Perakis, S.S.; Robin-Abbott, M. J.; Stoddard, J.L.; Weathers, K.C.; Dennis, R.L.

2011-01-01

Human activity in the last century has led to a significant increase in nitrogen (N) emissions and atmospheric deposition. This N deposition has reached a level that has caused or is likely to cause alterations to the structure and function of many ecosystems across the United States. One approach for quantifying the deposition of pollution that would be harmful to ecosystems is the determination of critical loads. A critical load is defined as the input of a pollutant below which no detrimental ecological effects occur over the long-term according to present knowledge. The objectives of this project were to synthesize current research relating atmospheric N deposition to effects on terrestrial and freshwater ecosystems in the United States, and to estimate associated empirical N critical loads. The receptors considered included freshwater diatoms, mycorrhizal fungi, lichens, bryophytes, herbaceous plants, shrubs, and trees. Ecosystem impacts included: (1) biogeochemical responses and (2) individual species, population, and community responses. Biogeochemical responses included increased N mineralization and nitrification (and N availability for plant and microbial uptake), increased gaseous N losses (ammonia volatilization, nitric and nitrous oxide from nitrification and denitrification), and increased N leaching. Individual species, population, and community responses included increased tissue N, physiological and nutrient imbalances, increased growth, altered root : shoot ratios, increased susceptibility to secondary stresses, altered fire regime, shifts in competitive interactions and community composition, changes in species richness and other measures of biodiversity, and increases in invasive species. The range of critical loads for nutrient N reported for U.S. ecoregions, inland surface waters, and freshwater wetlands is 1-39 kg N.ha -1.yr -1, spanning the range of N deposition observed over most of the country. The empirical critical loads for N tend to increase in the following sequence for different life forms: diatoms, lichens and bryophytes, mycorrhizal fungi, herbaceous plants and shrubs, and trees. The critical load approach is an ecosystem assessment tool with great potential to simplify complex scientific information and communicate effectively with the policy community and the public. This synthesis represents the first comprehensive assessment of empirical critical loads of N for major ecoregions across the United States. ?? 2011 by the Ecological Society of America.

Atmospheric nitrogen deposition to China: A model analysis on nitrogen budget and critical load exceedance

NASA Astrophysics Data System (ADS)

Zhao, Yuanhong; Zhang, Lin; Chen, Youfan; Liu, Xuejun; Xu, Wen; Pan, Yuepeng; Duan, Lei

2017-03-01

We present a national-scale model analysis on the sources and processes of inorganic nitrogen deposition over China using the GEOS-Chem model at 1/2° × 1/3° horizontal resolution. Model results for 2008-2012 are evaluated with an ensemble of surface measurements of wet deposition flux and gaseous ammonia (NH3) concentration, and satellite measurements of tropospheric NO2 columns. Annual total inorganic nitrogen deposition fluxes are simulated to be generally less than 10 kg N ha-1 a-1 in western China (less than 2 kg N ha-1 a-1 over Tibet), 15-50 kg N ha-1 a-1 in eastern China, and 16.4 kg N ha-1 a-1 averaged over China. Annual total deposition to China is 16.4 Tg N, with 10.2 Tg N (62%) from reduced nitrogen (NHx) and 6.2 Tg N from oxidized nitrogen (NOy). Domestic anthropogenic sources contribute 86% of the total deposition; foreign anthropogenic sources 7% and natural sources 7%. Annually 23% of domestically emitted NH3 and 36% for NOx are exported outside the terrestrial land of China. We find that atmospheric nitrogen deposition is about half of the nitrogen input from fertilizer application (29.6 Tg N a-1), and is much higher than that from natural biological fixation (7.3 Tg N a-1) over China. A comparison of nitrogen deposition with critical load estimates for eutrophication indicates that about 15% of the land over China experiences critical load exceedances, demonstrating the necessity of nitrogen emission controls to avoid potential negative ecological effects.

Euler Strut: A Mechanical Analogy for Dynamics in the Vicinity of a Critical Point

ERIC Educational Resources Information Center

Bobnar, Jaka; Susman, Katarina; Parsegian, V. Adrian; Rand, Peter R.; Cepic, Mojca; Podgornik, Rudolf

2011-01-01

An anchored elastic filament (Euler strut) under an external point load applied to its free end is a simple model for a second-order phase transition. In the static case, a load greater than the critical load causes a Euler buckling instability, leading to a change in the filament's shape. The analysis of filament dynamics with an external point…

A Study of BMP-2-Loaded Bipotential Electrolytic Complex around a Biphasic Calcium Phosphate-Derived (BCP) Scaffold for Repair of Large Segmental Bone Defect

PubMed Central

Paul, Kallyanashis; Padalhin, Andrew R.; Linh, Nguyen Thuy Ba; Kim, Boram; Sarkar, Swapan Kumar; Lee, Byong Taek

2016-01-01

A bipotential polyelectrolyte complex with biphasic calcium phosphate (BCP) powder dispersion provides an excellent option for protein adsorption and cell attachment and can facilitate enhanced bone regeneration. Application of the bipotential polyelectrolyte complex embedded in a spongy scaffold for faster healing of large segmental bone defects (LSBD) can be a promising endeavor in tissue engineering application. In the present study, a hollow scaffold suitable for segmental long bone replacement was fabricated by the sponge replica method applying the microwave sintering process. The fabricated scaffold was coated with calcium alginate at the shell surface, and genipin-crosslinked chitosan with biphasic calcium phosphate (BCP) dispersion was loaded at the central hollow core. The chitosan core was subsequently loaded with BMP-2. The electrolytic complex was characterized using SEM, porosity measurement, FTIR spectroscopy and BMP-2 release for 30 days. In vitro studies such as MTT, live/dead, cell proliferation and cell differentiation were performed. The scaffold was implanted into a 12 mm critical size defect of a rabbit radius. The efficacy of this complex is evaluated through an in vivo study, one and two month post implantation. BV/TV ratio for BMP-2 loaded sample was (42±1.76) higher compared with hollow BCP scaffold (32±0.225). PMID:27711142

Application of the ReNuMa model in the Sha He river watershed: tools for watershed environmental management.

PubMed

Sha, Jian; Liu, Min; Wang, Dong; Swaney, Dennis P; Wang, Yuqiu

2013-07-30

Models and related analytical methods are critical tools for use in modern watershed management. A modeling approach for quantifying the source apportionment of dissolved nitrogen (DN) and associated tools for examining the sensitivity and uncertainty of the model estimates were assessed for the Sha He River (SHR) watershed in China. The Regional Nutrient Management model (ReNuMa) was used to infer the primary sources of DN in the SHR watershed. This model is based on the Generalized Watershed Loading Functions (GWLF) and the Net Anthropogenic Nutrient Input (NANI) framework, modified to improve the characterization of subsurface hydrology and septic system loads. Hydrochemical processes of the SHR watershed, including streamflow, DN load fluxes, and corresponding DN concentration responses, were simulated following calibrations against observations of streamflow and DN fluxes. Uncertainty analyses were conducted with a Monte Carlo analysis to vary model parameters for assessing the associated variations in model outputs. The model performed accurately at the watershed scale and provided estimates of monthly streamflows and nutrient loads as well as DN source apportionments. The simulations identified the dominant contribution of agricultural land use and significant monthly variations. These results provide valuable support for science-based watershed management decisions and indicate the utility of ReNuMa for such applications. Copyright © 2013 Elsevier Ltd. All rights reserved.

Novel thermosensitive polymeric micelles for docetaxel delivery.

PubMed

Yang, Mi; Ding, Yitao; Zhang, Leyang; Qian, Xiaoping; Jiang, Xiqun; Liu, Baorui

2007-06-15

Targeted delivery of antitumor drugs triggered by hyperthermia has significant advantages in clinical applications, since it is easy to implement and side effects are reduced. To release drugs site-specifically upon local heating often requires the drugs to be loaded into a thermosensitive polymer matrix with a low critical solution temperature (LCST) between 37 and 42 degrees C. However, the LCSTs of most thermosensitive materials were below 37 degrees C, which limits their application in clinic because they would precipitate once injected into human body and lost thermal targeting function. Herein, we prepared a novel thermosensitive copolymer (poly(N-isopropylacrylamide-co-acrylamide)-b-poly (DL-lactide)) that exhibits no obvious physical change up to 41 degrees C when heated. Docetaxel loaded micelles made of such thermosensitive polymer were prepared by dialysis method and the maximum loading content was found to be up to 27%. The physical properties, such as structure, morphology, and size distribution of the micelles with and without docetaxel were investigated by NMR, X-ray diffraction, dynamic light scattering, atomic force microscopy, etc. The efficacy of this drug delivery system was also evaluated by examining the proliferation inhibiting activity against different cell lines in vitro. After hyperthermia, the cytotoxicity of docetaxel-loaded micelles increased prominently. Our results demonstrated that this copolymer could be an ideal candidate for thermal targeted antitumor drug delivery. (c) 2007 Wiley Periodicals, Inc.

Susceptibility of forests in the northeastern USA to nitrogen and sulfur deposition: critical load exceedance and forest health

Treesearch

N. Duarte; L.H. Pardo; M.J. Robin-Abbott

2013-01-01

The objectives of this study were to assess susceptibility to acidification and nitrogen (N) saturation caused by atmospheric deposition to northeastern US forests, evaluate the benefits and shortcomings of making critical load assessments using regional data, and assess the relationship between expected risk (exceedance) and forest health. We calculated the critical...

Polyamidoamine dendrimer-based binders for high-loading lithium–sulfur battery cathodes

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bhattacharya, Priyanka; Nandasiri, Manjula I.; Lv, Dongping

2016-01-01

Lithium-sulfur (Li-S) batteries are regarded as one of the most promising candidates for next generation energy storage systems because of their ultra high theoretical specific energy. To realize the practical application of Li-S batteries, however, a high S active material loading is essential (>70 wt% in the carbon-sulfur (C-S) composite cathode and >2 mg cm-2 in the electrode). A critical challenge to achieving this high capacity in practical electrodes is the dissolution of the longer lithium polysulfide reaction intermediates in the electrolyte (resulting in loss of active material from the cathode and contamination of the anode due to the polysulfidemore » shuttle mechanism). The binder material used for the cathode is therefore crucial as this is a key determinant of the bonding interactions between the active material (S) and electronic conducting support (C), as well as the maintenance of intimate contact between the electrode materials and current collector. The battery performance can thus be directly correlated with the choice of binder, but this has received only minimal attention in the relevant Li-S battery published literature. Here, we investigated the application of polyamidoamine (PAMAM) dendrimers as functional binders in Li-S batteries—a class of materials which has been unexplored for electrode design. By using dendrimers, it is demonstrated that high S loadings (>4 mg cm-2) can be easily achieved using "standard" (not specifically tailored) materials and simple processing methods. An exceptional electrochemical cycling performance was obtained (as compared to cathodes with conventional linear polymeric binders such as carboxymethyl cellulose (CMC) and styrene-butadiene rubber (SBR)) with >100 cycles and 85-98% capacity retention, thus demonstrating the significant utility of this new binder architecture which exhibits critical physicochemical properties and flexible nanoscale design parameters (CNDP's).« less

Elevated temperature crack growth

NASA Technical Reports Server (NTRS)

Kim, K. S.; Vanstone, R. H.

1992-01-01

The purpose of this program was to extend the work performed in the base program (CR 182247) into the regime of time-dependent crack growth under isothermal and thermal mechanical fatigue (TMF) loading, where creep deformation also influences the crack growth behavior. The investigation was performed in a two-year, six-task, combined experimental and analytical program. The path-independent integrals for application to time-dependent crack growth were critically reviewed. The crack growth was simulated using a finite element method. The path-independent integrals were computed from the results of finite-element analyses. The ability of these integrals to correlate experimental crack growth data were evaluated under various loading and temperature conditions. The results indicate that some of these integrals are viable parameters for crack growth prediction at elevated temperatures.

A translational velocity command system for VTOL low speed flight

NASA Technical Reports Server (NTRS)

Merrick, V. K.

1982-01-01

A translational velocity flight controller, suitable for very low speed maneuvering, is described and its application to a large class of VTOL aircraft from jet lift to propeller driven types is analyzed. Estimates for the more critical lateral axis lead to the conclusion that the controller would provide a jet lift (high disk loading) VTOL aircraft with satisfactory "hands off" station keeping in operational conditions more stringent than any specified in current or projected requirements. It also seems likely that ducted fan or propeller driven (low disk loading) VTOL aircraft would have acceptable hovering handling qualities even in high turbulence, although in these conditions pilot intervention to maintain satisfactory station keeping would probably be required for landing in restricted areas.

A novel modeling to predict the critical current behavior of Nb3Sn PIT strand under transverse load based on a scaling law and Finite Element Analysis

NASA Astrophysics Data System (ADS)

Wang, Tiening; Chiesa, Luisa; Takayasu, Makoto; Bordini, Bernardo

2014-09-01

Superconducting Nb3Sn Powder-In-Tube (PIT) strands could be used for the superconducting magnets of the next generation Large Hadron Collider. The strands are cabled into the typical flat Rutherford cable configuration. During the assembly of a magnet and its operation the strands experience not only longitudinal but also transverse load due to the pre-compression applied during the assembly and the Lorentz load felt when the magnets are energized. To properly design the magnets and guarantee their safe operation, mechanical load effects on the strand superconducting properties are studied extensively; particularly, many scaling laws based on tensile load experiments have been established to predict the critical current dependence on strain. However, the dependence of the superconducting properties on transverse load has not been extensively studied so far. One of the reasons is that transverse loading experiments are difficult to conduct due to the small diameter of the strand (about 1 mm) and the data currently available do not follow a common measurement standard making the comparison between different data sets difficult. Recently at the University of Geneva, a new device has been developed to characterize the critical current of Nb3Sn strands under transverse loads. In this work we present a new 2D Finite Element Analysis (FEA) to predict the electro-mechanical response of a PIT strand that was tested at the University of Geneva when transverse load is applied. The FEA provides the strain map for the superconducting filaments when the load is applied. Those strain maps are then used to evaluate the critical current behavior of a PIT strand using a recently developed scaling law that correlates the superconducting properties of a wire with the strain invariants due to the load applied on the superconductor. The benefits and limitations of this method are discussed based on the comparison between the critical current simulation results obtained with the filament strain map and the experimental results available for PIT strands.

Atmospheric deposition and canopy exchange processes in alpine forest ecosystems (northern Italy)

NASA Astrophysics Data System (ADS)

Balestrini, Raffaella; Tagliaferri, Antonio

Throughfall and bulk precipitation chemistry were studied for five years (June 1994-May 1999) at two high elevation forest sites (Val Gerola and Val Masino) which were known to differ in terms of tree health, as assessed by live crown condition. The ion concentration of bulk precipitation samples did not differ significantly between sites, except for Mg 2+, while the throughfall concentrations differed in the measured values of H +, N-NO 3-, Cl -, Na +, K +, DOC and weak organic acids. The results of the application of the canopy exchange model indicated a higher contribution from the dry deposition of N-NO 3-, N-NH 4+ and H + at Val Gerola, where the damage symptoms were more evident. In addition, the canopy leaching of Ca 2+, K + and weak organic acids were 47%, 21% and 27% higher at Val Gerola than at Val Masino. Annual SO 42- deposition fluxes (21.3 kg ha -1 yr -1 at Val Masino and 23.6 kg ha -1 yr -1 at Val Gerola) were similar to those reported for moderately polluted European and U.S. sites. Annual N loads were 13.6 and 13.1 kg ha -1 yr -1 in the bulk input, and 15.0 and 18.0 kg ha -1 yr -1 in throughfall inputs, at Val Masino and Val Gerola, respectively. The contribution of the organic fraction to the total N atmospheric deposition load is significant, constituting 17% of the bulk flux and 40% of the throughfall flux. Measured nitrogen loads exceed the critical nutrient loads by several kg N ha -1 at both stations. In particular the nitrogen throughfall load at Val Gerola was about 3 times higher than the critical values.

Residual strength of thin panels with cracks

NASA Technical Reports Server (NTRS)

Madenci, Erdogan

1994-01-01

The previous design philosophies involving safe life, fail-safe and damage tolerance concepts become inadequate for assuring the safety of aging aircraft structures. For example, the failure mechanism for the Aloha Airline accident involved the coalescence of undetected small cracks at the rivet holes causing a section of the fuselage to peel open during flight. Therefore, the fuselage structure should be designed to have sufficient residual strength under worst case crack configurations and in-flight load conditions. Residual strength is interpreted as the maximum load carrying capacity prior to unstable crack growth. Internal pressure and bending moment constitute the two major components of the external loads on the fuselage section during flight. Although the stiffeners in the form of stringers, frames and tear straps sustain part of the external loads, the significant portion of the load is taken up by the skin. In the presence of a large crack in the skin, the crack lips bulge out with considerable yielding; thus, the geometric and material nonlinearities must be included in the analysis for predicting residual strength. Also, these nonlinearities do not permit the decoupling of in-plane and out-of-plane bending deformations. The failure criterion combining the concepts of absorbed specific energy and strain energy density addresses the aforementioned concerns. The critical absorbed specific energy (local toughness) for the material is determined from the global specimen response and deformation geometry based on the uniaxial tensile test data and detailed finite element modeling of the specimen response. The use of the local toughness and stress-strain response at the continuum level eliminates the size effect. With this critical parameter and stress-strain response, the finite element analysis of the component by using STAGS along with the application of this failure criterion provides the stable crack growth calculations for residual strength predictions.

New Design for an Adjustable Cise Space Maintainer

PubMed Central

2018-01-01

Objective The aim of this study is to present a new adjustable Cise space maintainer for preventive orthodontic applications. Methods Stainless steel based new design consists of six main components. In order to understand the major displacement and stress fields, structural analysis for the design is considered by using finite element method. Results Similar to major displacement at y-axis, critical stresses σx and τxy possess a linear distribution with constant increasing. Additionally, strain energy density (SED) plays an important role to determine critical biting load capacity. Conclusion Structural analysis shows that the space maintainer is stable and is used for maintaining and/or regaining the space which arouses early loss of molar tooth. PMID:29854764

The current state of knowledge on the interaction of Escherichia coli within vegetative filter strips as a sustainable best management practice to reduce fecal pathogen loading into surface waters

PubMed Central

Olilo, Casianes Owino; Muia, Anastasia Wairimu; Moturi, Wilkister Nyaora; Onyando, Japhet Ogalo; Amber, Ford Roegner

2016-01-01

Agro-pastoral operations have the potential to threaten public health with loading of diverse pathogens into surface waters through overland flow; increasing awareness of the limitations of fecal indicators has led to development of a number of advancements in detection, source tracking and predictive modeling of public health risk. These tools and techniques are beginning to be integrated into management strategies. The objective of this review was to determine the status of current knowledge and challenges of the fate and transport of Escherichia coli in overland flow and their interaction within vegetative filter strip (VFS) as one of these implemented best management practices and to critically evaluate its use in that setting as an indicator organism. With few studies directly focusing on VFS removal of E. coli from overland flow, we critically evaluated the available data on movement of E. coil from fecal source loading to retention and decay or re-release for potential contamination of water ways and pointed out potential limitations in both pathogen-specific removal and its use as an indicator organisms within overland flow and VFS. Critical areas of focus for future studies to reduce gaps in knowledge were identified, and the integration of newer approaches in source tracking, alternative indicators and the use of non-pathogenic surrogates for field testing of existing VFS models was encouraged. With VFS as a growing field of interest as an economical conservation practice and as an avenue for conservation of resources for small-scale agro-pastoral operations, management strategies to reduce initial fecal load from either applied manure constituents or shedding from free-range animals will continue to test the limits in the applications of models to overland flow and VFS management strategies. Further studies at the microscale in understanding discrepancies between low and high pathogenicity strains of E. coil and between E. coil and other fecal pathogens in the context of VFS will be critical. However, nuanced studies are needed to understand either biological or environmental differences in the fate and transport of the diverse types of fecal pathogens within these settings PMID:28042601

Assessment of the transportation route of oversize and excessive loads in relation to the load-bearing capacity of existing bridges

NASA Astrophysics Data System (ADS)

Doležel, Jiří; Novák, Drahomír; Petrů, Jan

2017-09-01

Transportation routes of oversize and excessive loads are currently planned in relation to ensure the transit of a vehicle through critical points on the road. Critical points are level-intersection of roads, bridges etc. This article presents a comprehensive procedure to determine a reliability and a load-bearing capacity level of the existing bridges on highways and roads using the advanced methods of reliability analysis based on simulation techniques of Monte Carlo type in combination with nonlinear finite element method analysis. The safety index is considered as a main criterion of the reliability level of the existing construction structures and the index is described in current structural design standards, e.g. ISO and Eurocode. An example of a single-span slab bridge made of precast prestressed concrete girders of the 60 year current time and its load bearing capacity is set for the ultimate limit state and serviceability limit state. The structure’s design load capacity was estimated by the full probability nonlinear MKP analysis using a simulation technique Latin Hypercube Sampling (LHS). Load-bearing capacity values based on a fully probabilistic analysis are compared with the load-bearing capacity levels which were estimated by deterministic methods of a critical section of the most loaded girders.

Load application for the contact mechanics analysis and wear prediction of total knee replacement.

PubMed

Zhang, Jing; Chen, Zhenxian; Wang, Ling; Li, Dichen; Jin, Zhongmin

2017-05-01

Tibiofemoral contact forces in total knee replacement have been measured at the medial and lateral sites respectively using an instrumented prosthesis, and predicted from musculoskeletal multibody dynamics models with a reasonable accuracy. However, it is uncommon that the medial and lateral forces are applied separately to replace a total axial load according to the ISO standard in the majority of current finite element analyses. In this study, we quantified the different effects of applying the medial and lateral loads separately versus the traditional total axial load application on contact mechanics and wear prediction of a patient-specific knee prosthesis. The load application position played an important role under the medial-lateral load application. The loading set which produced the closest load distribution to the multibody dynamics model was used to predict the contact mechanics and wear for the prosthesis and compared with the total axial load application. The medial-lateral load distribution using the present method was found to be closer to the multibody dynamics prediction than the traditional total axial load application, and the maximum contact pressure and contact area were consistent with the corresponding load variation. The predicted total volumetric wear rate and area were similar between the two load applications. However, the split of the predicted wear volumes on the medial and the lateral sides was different. The lateral volumetric wear rate was 31.46% smaller than the medial from the traditional load application prediction, while from the medial-lateral load application, the lateral side was only 11.8% smaller than the medial. The medial-lateral load application could provide a new and more accurate method of load application for patient-specific preclinical contact mechanics and wear prediction of knee implants.

Critical loads of nitrogen deposition and critical levels of atmospheric ammonia for mediterranean evergreen woodlands

NASA Astrophysics Data System (ADS)

Pinho, P.; Theobald, M. R.; Dias, T.; Tang, Y. S.; Cruz, C.; Martins-Loução, M. A.; Máguas, C.; Sutton, M.; Branquinho, C.

2011-11-01

Nitrogen (N) has emerged in recent years as a key factor associated with global changes, with impacts on biodiversity, ecosystems functioning and human health. In order to ameliorate the effects of excessive N, safety thresholds have been established, such as critical loads (deposition fluxes) and levels (concentrations). For Mediterranean ecosystems, few studies have been carried out to assess these parameters. Our objective was therefore to determine the critical loads of N deposition and long-term critical levels of atmospheric ammonia for Mediterranean evergreen woodlands. For that we have considered changes in epiphytic lichen communities, which have been shown to be one of the most sensitive to excessive N. Based on a classification of lichen species according to their tolerance to N we grouped species into response functional groups, which we used as a tool to determine the critical loads and levels. This was done under Mediterranean climate, in evergreen cork-oak woodlands, by sampling lichen functional diversity and annual atmospheric ammonia concentrations and modelling N deposition downwind from a reduced N source (a cattle barn). By modelling the highly significant relationship between lichen functional groups and N deposition, the critical load was estimated to be below 26 kg (N) ha-1 yr-1, which is within the upper range established for other semi-natural ecosystems. By modelling the highly significant relationship of lichen functional groups with annual atmospheric ammonia concentration, the critical level was estimated to be below 1.9 μg m-3, in agreement with recent studies for other ecosystems. Taking into account the high sensitivity of lichen communities to excessive N, these values should be taken into account in policies that aim at protecting Mediterranean woodlands from the initial effects of excessive N.

Modeling elastic wave propagation in kidney stones with application to shock wave lithotripsy.

PubMed

Cleveland, Robin O; Sapozhnikov, Oleg A

2005-10-01

A time-domain finite-difference solution to the equations of linear elasticity was used to model the propagation of lithotripsy waves in kidney stones. The model was used to determine the loading on the stone (principal stresses and strains and maximum shear stresses and strains) due to the impact of lithotripsy shock waves. The simulations show that the peak loading induced in kidney stones is generated by constructive interference from shear waves launched from the outer edge of the stone with other waves in the stone. Notably the shear wave induced loads were significantly larger than the loads generated by the classic Hopkinson or spall effect. For simulations where the diameter of the focal spot of the lithotripter was smaller than that of the stone the loading decreased by more than 50%. The constructive interference was also sensitive to shock rise time and it was found that the peak tensile stress reduced by 30% as rise time increased from 25 to 150 ns. These results demonstrate that shear waves likely play a critical role in stone comminution and that lithotripters with large focal widths and short rise times should be effective at generating high stresses inside kidney stones.

Pre-strain effect on frequency-based impact energy dissipation through a silicone foam pad for shock mitigation [Pre-strain effect on the frequency response of shock mitigation through a silicone foam pad

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sanborn, Brett; Song, Bo; Smith, Scott

Silicone foams have been used in a variety of applications from gaskets to cushioning pads over a wide range of environments. Particularly, silicone foams are used as a shock mitigation material for shock and vibration applications. Understanding the shock mitigation response, particularly in the frequency domain, is critical for optimal designs to protect internal devices and components more effectively and efficiently. The silicone foams may be subjected to pre-strains during the assembly process which may consequently influence the frequency response with respect to shock mitigation performance. A Kolsky compression bar was modified with pre-compression capabilities to characterize the shock mitigationmore » response of silicone foam in the frequency domain to determine the effect of pre-strain. Lastly, a silicone sample was also intentionally subjected to repeated pre-strain and dynamic loadings to explore the effect of repeated loading on the frequency response of shock mitigation.« less

Some Interesting Applications of Probabilistic Techiques in Structural Dynamic Analysis of Rocket Engines

NASA Technical Reports Server (NTRS)

Brown, Andrew M.

2014-01-01

Numerical and Analytical methods developed to determine damage accumulation in specific engine components when speed variation included. Dither Life Ratio shown to be well over factor of 2 for specific example. Steady-State assumption shown to be accurate for most turbopump cases, allowing rapid calculation of DLR. If hot-fire speed data unknown, Monte Carlo method developed that uses speed statistics for similar engines. Application of techniques allow analyst to reduce both uncertainty and excess conservatism. High values of DLR could allow previously unacceptable part to pass HCF criteria without redesign. Given benefit and ease of implementation, recommend that any finite life turbomachine component analysis adopt these techniques. Probability Values calculated, compared, and evaluated for several industry-proposed methods for combining random and harmonic loads. Two new excel macros written to calculate combined load for any specific probability level. Closed form Curve fits generated for widely used 3(sigma) and 2(sigma) probability levels. For design of lightweight aerospace components, obtaining accurate, reproducible, statistically meaningful answer critical.

Integrated Application of Active Controls (IAAC) technology to an advanced subsonic transport project. ACT/Control/Guidance System study, volume 1

NASA Technical Reports Server (NTRS)

1982-01-01

The active control technology (ACT) control/guidance system task of the integrated application of active controls (IAAC) technology project within the NASA energy efficient transport program was documented. The air traffic environment of navigation and air traffic control systems and procedures were extrapolated. An approach to listing flight functions which will be performed by systems and crew of an ACT configured airplane of the 1990s, and a determination of function criticalities to safety of flight, are the basis of candidate integrated ACT/Control/Guidance System architecture. The system mechanizes five active control functions: pitch augmented stability, angle of attack limiting, lateral/directional augmented stability, gust load alleviation, and maneuver load control. The scope and requirements of a program for simulating the integrated ACT avionics and flight deck system, with pilot in the loop, are defined, system and crew interface elements are simulated, and mechanization is recommended. Relationships between system design and crew roles and procedures are evaluated.

Pre-strain effect on frequency-based impact energy dissipation through a silicone foam pad for shock mitigation [Pre-strain effect on the frequency response of shock mitigation through a silicone foam pad

DOE PAGES

Sanborn, Brett; Song, Bo; Smith, Scott

2015-12-29

Silicone foams have been used in a variety of applications from gaskets to cushioning pads over a wide range of environments. Particularly, silicone foams are used as a shock mitigation material for shock and vibration applications. Understanding the shock mitigation response, particularly in the frequency domain, is critical for optimal designs to protect internal devices and components more effectively and efficiently. The silicone foams may be subjected to pre-strains during the assembly process which may consequently influence the frequency response with respect to shock mitigation performance. A Kolsky compression bar was modified with pre-compression capabilities to characterize the shock mitigationmore » response of silicone foam in the frequency domain to determine the effect of pre-strain. Lastly, a silicone sample was also intentionally subjected to repeated pre-strain and dynamic loadings to explore the effect of repeated loading on the frequency response of shock mitigation.« less

Dimension-controlled formation of crease patterns on soft solids.

PubMed

Tang, Shan; Gao, Bo; Zhou, Zhiheng; Gu, Qiang; Guo, Tianfu

2017-01-18

Soft solids such as PDMS or silicone are widely needed in many advanced applications such as flexible electronics and medical engineering. The ability to control the structure and properties of the surface of soft solids provides new opportunities in these applications. In particular, mechanical loading induced elastic instability is a convenient method to control the surface morphology. The critical strain at which the crease nucleates is experimentally measured under plane strain conditions, and is found to be consistent with that predicted by nonlinear large deformation theory of creases. Under compressive loading, we find that silicone undergoes a transition of creasing pattern from a single channeling or double channeling crease to an unchanneling crease, depending on the specimen's width and height. Finite element simulations are performed to better understand the underlying mechanism of creasing, wherein a relationship between the depth and spacing of the creases is established. It is found to be in good agreement with the experimental data obtained.

Twenty years of load theory-Where are we now, and where should we go next?

PubMed

Murphy, Gillian; Groeger, John A; Greene, Ciara M

2016-10-01

Selective attention allows us to ignore what is task-irrelevant and focus on what is task-relevant. The cognitive and neural mechanisms that underlie this process are key topics of investigation in cognitive psychology. One of the more prominent theories of attention is perceptual load theory, which suggests that the efficiency of selective attention is dependent on both perceptual and cognitive load. It is now more than 20 years since the proposal of load theory, and it is a good time to evaluate the evidence in support of this influential model. The present article supplements and extends previous reviews (Lavie, Trends in Cognitive Sciences, 9, 75-82. doi: 10.1016/j.tics.2004.12.004 , 2005, Current Directions in Psychological Science, 19, 143-148. doi: 10.1177/0963721410370295 , 2010) by examining more recent research in what appears to be a rapidly expanding area. The article comprises five parts, examining (1) evidence for the effects of perceptual load on attention, (2) cognitive load, (3) individual differences under load, (4) alternative theories and criticisms, and (5) the future of load theory. We argue that the key next step for load theory will be the application of the model to real-world tasks. The potential benefits of applied attention research are numerous, and there is tentative evidence that applied research would provide strong support for the theory itself, as well as real-world benefits related to activities in which attention is crucial, such as driving and education.

Comparison among model estimates of critical loads of acidic deposition using different sources and scales of input data

Treesearch

T.C. McDonnell; B.J. Cosby; T.J. Sullivan; S.G. McNulty; E.C. Cohen

2010-01-01

The critical load (CL) of acidic atmospheric deposition represents the load of acidity deposited from the atmosphere to the earth’s surface at which harmful acidification effects on sensitive biological receptors are thought to occur. In this study, the CL for forest soils was estimated for 27 watersheds throughout the United States using a steady-state mass balance...

14 CFR 27.787 - Cargo and baggage compartments.

Code of Federal Regulations, 2010 CFR

2010-01-01

... AIRCRAFT AIRWORTHINESS STANDARDS: NORMAL CATEGORY ROTORCRAFT Design and Construction Personnel and Cargo... for its placarded maximum weight of contents and for the critical load distributions at the... authorized weight of cargo and baggage at the critical loading distribution. (d) If cargo compartment lamps...

Effects of Mental Load and Fatigue on Steady-State Evoked Potential Based Brain Computer Interface Tasks: A Comparison of Periodic Flickering and Motion-Reversal Based Visual Attention.

PubMed

Xie, Jun; Xu, Guanghua; Wang, Jing; Li, Min; Han, Chengcheng; Jia, Yaguang

Steady-state visual evoked potentials (SSVEP) based paradigm is a conventional BCI method with the advantages of high information transfer rate, high tolerance to artifacts and the robust performance across users. But the occurrence of mental load and fatigue when users stare at flickering stimuli is a critical problem in implementation of SSVEP-based BCIs. Based on electroencephalography (EEG) power indices α, θ, θ + α, ratio index θ/α and response properties of amplitude and SNR, this study quantitatively evaluated the mental load and fatigue in both of conventional flickering and the novel motion-reversal visual attention tasks. Results over nine subjects revealed significant mental load alleviation in motion-reversal task rather than flickering task. The interaction between factors of "stimulation type" and "fatigue level" also illustrated the motion-reversal stimulation as a superior anti-fatigue solution for long-term BCI operation. Taken together, our work provided an objective method favorable for the design of more practically applicable steady-state evoked potential based BCIs.

Design of calcium phosphate ceramics for drug delivery applications in bone diseases: A review of the parameters affecting the loading and release of the therapeutic substance.

PubMed

Parent, Marianne; Baradari, Hiva; Champion, Eric; Damia, Chantal; Viana-Trecant, Marylène

2017-04-28

Effective treatment of critical-size defects is a key challenge in restorative surgery of bone. The strategy covers the implantation of biocompatible, osteoconductive, bioactive and biodegradable devices which (1) well interact with native tissue, mimic multi-dimensional and hierarchical structure of bone and (2) are able to enhance bone repair, treating post implantation pathologies or bone diseases by local delivery of therapeutic agents. Among different options, calcium phosphate biomaterials are found to be attractive choices, due to their excellent biocompatibility, customisable bioactivity and biodegradability. Several approaches have been established to enhance this material ability to be loaded with a therapeutic agent, in order to obtain an in situ controlled release that meets the clinical needs. This article reviews the most important factors influencing on both drug loading and release capacity of porous calcium phosphate bone substitutes. Characteristics of the carrier, drug/carrier interactions, experimental conditions of drug loading and evaluation of drug delivery are considered successively. Copyright © 2017 Elsevier B.V. All rights reserved.

Eutrophic lichens respond to multiple forms of N: implications for critical levels and critical loads research

Treesearch

Sarah Jovan; Jennifer Riddell; Pamela E Padgett; Thomas Nash

2012-01-01

Epiphytic lichen communities are highly sensitive to excess nitrogen (N), which causes the replacement of native floras by N-tolerant, ‘‘weedy’’ eutrophic species. This shift is commonly used as the indicator of ecosystem ‘‘harm’’ in studies developing empirical critical levels (CLE) for ammonia (NH3) and critical loads (CLO) for N. To be most...

Phase-field model simulation of ferroelectric/antiferroelectric materials microstructure evolution under multiphysics loading

NASA Astrophysics Data System (ADS)

Zhang, Jingyi

Ferroelectric (FE) and closely related antiferroelectric (AFE) materials have unique electromechanical properties that promote various applications in the area of capacitors, sensors, generators (FE) and high density energy storage (AFE). These smart materials with extensive applications have drawn wide interest in the industrial and scientific world because of their reliability and tunable property. However, reliability issues changes its paradigms and requires guidance from detailed mechanism theory as the materials applications are pushed for better performance. A host of modeling work were dedicated to study the macro-structural behavior and microstructural evolution in FE and AFE material under various conditions. This thesis is focused on direct observation of domain evolution under multiphysics loading for both FE and AFE material. Landau-Devonshire time-dependent phase field models were built for both materials, and were simulated in finite element software Comsol. In FE model, dagger-shape 90 degree switched domain was observed at preexisting crack tip under pure mechanical loading. Polycrystal structure was tested under same condition, and blocking effect of the growth of dagger-shape switched domain from grain orientation difference and/or grain boundary was directly observed. AFE ceramic model was developed using two sublattice theory, this model was used to investigate the mechanism of energy efficiency increase with self-confined loading in experimental tests. Consistent results was found in simulation and careful investigation of calculation results gave confirmation that origin of energy density increase is from three aspects: self-confinement induced inner compression field as the cause of increase of critical field, fringe leak as the source of elevated saturation polarization and uneven defects distribution as the reason for critical field shifting and phase transition speed. Another important affecting aspect in polycrystalline materials is the texture of material, textured materials have better alignment and the alignment reorganization is associated with inelastic strain. We developed a vector field of alignment to describe texture degree and introduced the alignment vector into our FE and AFE model. The model with alignment field gave quantatively results for the well-recognized irreversible strain in AFE virgin ceramics during the first poling process. The texture field also shows a shielding zone under mechanical loading around existing crack tip. In conclusion, this thesis developed working models of FE and AFE material and systematically studied their behavior under multiphysics loading in a finite element analysis approach. Materials structure of polycrystal materials including grain orientation, grain boundary, defects and materials texture were tested for their effect on hysteresis and switched domain growth. Detailed microstructure development in domain switching and alignment was directly observed in this simulation.

Estimating Critical Nitrogen Loads for a California Grassland

NASA Astrophysics Data System (ADS)

Weiss, S. B.

2007-12-01

Rigorously established critical nitrogen loads to protect biodiversity can be effective policy tools for addressing the insidious impacts of atmospheric N-deposition on ecosystems. This presentation describes methods for determining critical N-loads to a California grassland ecosystem by careful examination of the continuum from emissions, transport, atmospheric chemistry, deposition, ecosystem response, and impacts on biodiversity. Nutrient-poor soils derived from serpentinite bedrock support diverse native grasslands with dazzling wildflower displays and numerous threatened and endangered species, including the Bay checkerspot butterfly. Under moderate atmospheric N-deposition, these sites are rapidly invaded by introduced nitrophilous annual grasses in the absence of appropriate grazing or other management. Critical loads to this ecosystem have been approached by measurements of atmospheric concentrations of reactive N gases using Ogawa passive samplers and seasonally averaged deposition velocities. A regional-scale pollution gradient was complemented by a very local-scale pollution gradient extending a few hundred meters downwind of a heavily traveled road in a relatively unpolluted area. The local gradient suggests a critical load of 5 kg-N ha-1 a-1 or less. The passive monitor calculations largely agree with deposition calculated with the CMAQ model at 4 km scale. Emissions of NH3 from catalytic converters are the dominant N-source at the roadway site, and are a function of traffic volume and speed. Plant tissue N-content and 15N gradients support the existence of N-deposition gradients. The complexities of more detailed calculations and measurements specific to this ecosystem include seasonal changes in LAI, temporal coincidence of traffic emissions and stomatal conductance, surface moisture, changes in oxidized versus reduced N sources, and annual weather variation. The concept of a "critical cumulative load" may be appropriate over decadal time scales in this ecosystem and other semi-arid systems where N-export is minimal.

Critical loads of acidity for 90,000 lakes in northern Saskatchewan: A novel approach for mapping regional sensitivity to acidic deposition

NASA Astrophysics Data System (ADS)

Cathcart, H.; Aherne, J.; Jeffries, D. S.; Scott, K. A.

2016-12-01

Atmospheric emissions of sulphur dioxide (SO2) from large point sources are the primary concern for acidic deposition in western Canada, particularly in the Athabasca Oil Sands Region (AOSR) where prevailing winds may potentially carry SO2 over acid-sensitive lakes in northern Saskatchewan. A novel catchment-scale regression kriging approach was used to assess regional sensitivity and critical loads of acidity for the total lake population of northern Saskatchewan (89,947 lakes). Lake catchments were delineated using Thiessen polygons, and surface water chemistry was predicted for sensitivity indicators (calcium, pH, alkalinity, and acid neutralizing capacity). Critical loads were calculated with the steady state water chemistry model using regression-kriged base cations, sulphate, and dissolved organic carbon concentrations modelled from surface water observations (n > 800) and digital landscape-scale characteristics, e.g., climate, soil, vegetation, landcover, and geology maps. A large region (>13,726 km2) of two or more indicators of acid sensitivity (pH < 6 and acid neutralizing capacity, alkalinity, calcium < 50 μeq L-1) and low critical loads < 5 meq m-2 yr-1 were predicted on the Athabasca Basin. Exceedance of critical loads under 2006 modelled total sulphate deposition was predicted for 12% of the lakes (covering an area of 3742 km2), primarily located on the Athabasca Basin, within 100 km of the AOSR. There have been conflicting scientific reports of impacts from atmospheric emissions from the AOSR; the results of this study suggest that catchments in the Athabasca Basin within 100 km of the AOSR have received acidic deposition in excess of their critical loads and many of them may be at risk of ecosystem damage owing to their sensitivity.

Airborne soil dust and its importance in buffering of atmospheric acidity and critical load assessment, over the semi arid tract of northern India.

NASA Astrophysics Data System (ADS)

Sharma, Disha; Kulshrestha, Umesh

Airborne soil dust and its importance in buffering of atmospheric acidity and critical load assessment, over the semi arid tract of northern India. The Critical Load approach alongwith integrated assessment models has been used in the European nations for policy formations to reduce acidic emissions. This unique approach was applied to assess the of vulnerability of natural systems to the present day atmospheric pollution scenario. The calculated values of critical loads of sulphur ( 225 - 275 eq/ha/yr) and nitrogen (298 - 303 eq/ha/yr), for the soil system in Delhi, were calculated with respect to Anjan grass, Hibiscus and Black siris. The present loads of sulphur (PL(S) = 26.40 eq/ha/yr) and nitrogen (PL(N) = 36.51 eq/ha/yr) were found to be much lower than their critical loads without posing any danger of atmospheric acidic deposition on the soil systems. The study indicated that the system is still protective due to high pH of soil. The nature of buffering capability of calcium derived from soil dust can be considered as a natural tool to combat acidification in the Indian region. The results showed that the pollution status in Delhi is still within the safe limits. However, at the pace at which the city is growing, it is likely that in coming decades, it may exceed these critical values. In order to set deposition limits and avoid adverse effects of acidic deposition this approach can be applied in India too. Such approach is very useful, not only in abating pollution but also in devising means of cost optimal emission abatement strategies.

NASA Thermographic Inspection of Advanced Composite Materials

NASA Technical Reports Server (NTRS)

Cramer, K. Elliott

2004-01-01

As the use of advanced composite materials continues to increase in the aerospace community, the need for a quantitative, rapid, in situ inspection technology has become a critical concern throughout the industry. In many applications it is necessary to monitor changes in these materials over an extended period of time to determine the effects of various load conditions. Additionally, the detection and characterization of defects such as delaminations, is of great concern. This paper will present the application of infrared thermography to characterize various composite materials and show the advantages of different heat source types. Finally, various analysis methodologies used for quantitative material property characterization will be discussed.

Selected Aspects of Cryogenic Tank Fatigue Calculations for Offshore Application

NASA Astrophysics Data System (ADS)

Skrzypacz, J.; Jaszak, P.

2018-02-01

The paper presents the way of the fatigue life calculation of a cryogenic tank dedicated for the carriers ship application. The independent tank type C was taken into consideration. The calculation took into account a vast range of the load spectrum resulting in the ship accelerations. The stress at the most critical point of the tank was determined by means of the finite element method. The computation methods and codes used in the design of the LNG tank were presented. The number of fatigue cycles was determined by means of S-N curve. The cumulated linear damage theory was used to determine life factor.

Rate dependent constitutive behavior of dielectric elastomers and applications in legged robotics

NASA Astrophysics Data System (ADS)

Oates, William; Miles, Paul; Gao, Wei; Clark, Jonathan; Mashayekhi, Somayeh; Hussaini, M. Yousuff

2017-04-01

Dielectric elastomers exhibit novel electromechanical coupling that has been exploited in many adaptive structure applications. Whereas the quasi-static, one-dimensional constitutive behavior can often be accurately quantified by hyperelastic functions and linear dielectric relations, accurate predictions of electromechanical, rate-dependent deformation during multiaxial loading is non-trivial. In this paper, an overview of multiaxial electromechanical membrane finite element modeling is formulated. Viscoelastic constitutive relations are extended to include fractional order. It is shown that fractional order viscoelastic constitutive relations are superior to conventional integer order models. This knowledge is critical for transition to control of legged robotic structures that exhibit advanced mobility.

VEGA Launch Vehicle Vibro-Acoustic Approach for Multi Payload Configuration Qualification

NASA Astrophysics Data System (ADS)

Bartoccini, D.; Di Trapani, C.; Fotino, D.; Bonnet, M.

2014-06-01

Acoustic loads are one of the principal source of structural vibration and internal noise during a launch vehicle flight but do not generally present a critical design condition for the main load-carrying structure. However, acoustic loads may be critical to the proper functioning of vehicle components and their supporting structures, which are otherwise lightly loaded. Concerning the VEGA program, in order to demonstrate VEGA Launch Vehicle (LV) on-ground qualification, prior to flight, to the acoustic load, the following tests have been performed: small-scale acoustic test intended for the determination of the acoustic loading of the LV and its nature and full-scale acoustic chamber test to determine the vibro-acoustic response of the structures as well as of the acoustic cavities.

Buckling of Low Arches or Curved Beams of Small Curvature

NASA Technical Reports Server (NTRS)

Fung, Y C; Kaplan, A

1952-01-01

A general solution, based on the classical buckling criterion, is given for the problem of buckling of low arches under a lateral loading acting toward the center of curvature. For a sinusoidal arch under sinusoidal loading, the critical load can be expressed exactly as a simple function of the beam dimension parameters. For other arch shapes and load distributions, approximate values of the critical load can be obtained by summing a few terms of a rapidly converging Fourier series. The effects of initial end thrust and axial and lateral elastic support are discussed. The buckling load based on energy criterion of Karman and Tsien is also calculated. Results for both the classical and the energy criteria are compared with experimental results.

Microgrid optimized resource dispatch for public-purpose resiliency and sustainability

DOE Office of Scientific and Technical Information (OSTI.GOV)

Burr, Michael; Camilleri, John; Lubkeman, David

Communities in Atlantic coastal regions have in recent years sought to improve the resiliency of their critical infrastructure and public services, especially to protect against hurricanes and other events capable of causing widespread damage and disruption. As the backbone of any community’s critical functions, the electricity distribution system requires high resiliency in order to maintain local energy delivery services. Against this backdrop, the Project sought to develop a resilient energy microgrid control system capable of integrating distributed renewable energy resources, natural gas CHP units, energy storage, and demand-side management technologies in near-real-time optimization schemes for the community of Olney, Md.more » The Montgomery County Planning Board in 2005 established the Olney Town Center area as a “civic center/town commons,” in part because it serves as a key point of interaction in the community – but also because it contains numerous vital community assets. With a total peak electrical load of about 8 MW (including Montgomery General Hospital with a 2.4 MW peak), the Project area is a business and essential services area, directly serving a suburban population of more than 33,000 residents. It contains a hospital, police station, two fire stations, two schools, grocery stores, and gas stations, and the community’s water tower, among other things. Moreover, the location stands at the crossroads of two state highways that represent major regional arteries for commerce and public safety in Montgomery County. These characteristics made the Project area an appropriate setting for considering microgrid deployment. It presented a model of a typical Maryland suburban community, with geographic dispersion of vital assets over a sizeable area, and a combination of overhead distribution lines and underground cables serving those critical loads. Such a representative model helped to ensure the solutions developed and the scenarios tested would be readily applicable to other communities in the state and the region. Further, the Project’s outcomes and lessons provide insights to guide community microgrid design and development in many locations. To achieve Project objectives – including those established by the U.S. Department of Energy (DOE) National Energy Technology Laboratory – the Project team researched, developed, and tested in simulation a set of microgrid controls capable of maintaining electricity supplies for critical community loads in the event of a regional utility outage lasting many days or even weeks. Testing and analysis showed that the microgrid would be capable of maintaining electricity supply to critical loads essentially indefinitely in most outage scenarios, while also substantially improving overall reliability for microgrid customers. With targeted improvements in local utility distribution infrastructure, test analysis showed that the microgrid would be capable of reducing annual electricity outages for critical loads by 98%. Further, to help achieve environmental and efficiency policy goals established by both the State of Maryland and the federal government, the team designed the system to reduce the annual carbon footprint of served loads by 20%, and to improve system energy efficiency for those loads by at least 20%. Testing showed that, as designed, the system is capable of meeting these performance requirements, with potential for further improvements through more effective thermal energy utilization. This Final Report, comprised of four volumes and 11 annexes, presents the results of these project efforts, including feasibility assessment (section F) and guidance for decision-makers considering prospective deployment of public-purpose microgrid systems in Maryland communities.« less

First Demonstration on Direct Laser Fabrication of Lunar Regolith Parts

NASA Technical Reports Server (NTRS)

Balla, Vamsi Krishna; Roberson, Luke B.; OConnor, Gregory W. O.; Trigwell, Stephen; Bose, Susmita; Bandyopadhyay, Amit

2010-01-01

Establishment of a lunar or Martian outpost necessitates the development of methods to utilize in situ mineral resources for various construction and resource extraction applications. Fabrication technologies are critical for habitat structure development, as well as repair and replacement of tools and parts at the outpost. Herein we report the direct fabrication of lunar regolith simulant parts, in freeform environment, using lasers. We show that raw lunar regolith can be processed at laser energy levels as a low as 2.12 J mm-2 resulting in nanocrystalline and/or amorphous microstructures. Potential applications of laser based fabrication technologies to make useful regolith parts for various applications including load bearing composite structures, radiation shielding, and solar cell substrates is described.

Fracture Probability of MEMS Optical Devices for Space Flight Applications

NASA Technical Reports Server (NTRS)

Fettig, Rainer K.; Kuhn, Jonathan L.; Moseley, S. Harvey; Kutyrev, Alexander S.; Orloff, Jon

1999-01-01

A bending fracture test specimen design is presented for thin elements used in optical devices for space flight applications. The specimen design is insensitive to load position, avoids end effect complications, and can be used to measure strength of membranes less than 2 microns thick. The theoretical equations predicting stress at failure are presented, and a detailed finite element model is developed to validate the equations for this application. An experimental procedure using a focused ion beam machine is outlined, and results from preliminary tests of 1.9 microns thick single crystal silicon are presented. These tests are placed in the context of a methodology for the design and evaluation of mission critical devices comprised of large arrays of cells.

Critical acid load limits in a changing climate: implications and solutions

Treesearch

Steven G. McNulty

2010-01-01

The federal agencies of the United States are currently developing guidelines for critical nitrogen load limits for U.S. forest ecosystems. These guidelines will be used to develop regulations designed to maintain pollutant inputs below the level shown to damage specified ecosystems.

Effects of repeated bending load at room temperature for composite Nb3Sn wires

NASA Astrophysics Data System (ADS)

Awaji, Satoshi; Watanabe, Kazuo; Katagiri, Kazumune

2003-09-01

In order to realize a react and wind (R&W) method for Nb3Sn wires, the influences of a bending load at room temperature are investigated. Usually, the superconducting wires undergo bending loads at room temperature repeatedly during winding and insulation processes. We define these bending loads as 'pre-bending' treatments. We applied the pre-bending strain of 0 and 0.5% to the highly strengthened CuNb/(Nb, Ti)3Sn wires, and measured the stress/strain properties and critical currents. The improvements of stress dependence of normalized critical current and the increase of the maximum critical current by the pre-bending treatments were found. The model based on the distribution of the local tensile strain as a bending strain describes the experimental results well without the increase of the maximum critical current. When the pre-bending strain was applied, the calculated results indicate that the mechanical properties are improved due to the local work hardening, and hence the stress dependence of Ic increases.

Critical nitrogen deposition loads in high-elevation lakes of the western US inferred from paleolimnological records

USGS Publications Warehouse

Saros, J.E.; Clow, D.W.; Blett, T.; Wolfe, A.P.

2011-01-01

Critical loads of nitrogen (N) from atmospheric deposition were determined for alpine lake ecosystems in the western US using fossil diatom assemblages in lake sediment cores. Changes in diatom species over the last century were indicative of N enrichment in two areas, the eastern Sierra Nevada, starting between 1960 and 1965, and the Greater Yellowstone Ecosystem, starting in 1980. In contrast, no changes in diatom community structure were apparent in lakes of Glacier National Park. To determine critical N loads that elicited these community changes, we modeled wet nitrogen deposition rates for the period in which diatom shifts first occurred in each area using deposition data spanning from 1980 to 2007. We determined a critical load of 1.4 kg N ha-1 year-1 wet N deposition to elicit key nutrient enrichment effects on diatom communities in both the eastern Sierra Nevada and the Greater Yellowstone Ecosystem. ?? 2010 Springer Science+Business Media B.V.

[Nitrogen non-point source pollution identification based on ArcSWAT in Changle River].

PubMed

Deng, Ou-Ping; Sun, Si-Yang; Lü, Jun

2013-04-01

The ArcSWAT (Soil and Water Assessment Tool) model was adopted for Non-point source (NPS) nitrogen pollution modeling and nitrogen source apportionment for the Changle River watershed, a typical agricultural watershed in Southeast China. Water quality and hydrological parameters were monitored, and the watershed natural conditions (including soil, climate, land use, etc) and pollution sources information were also investigated and collected for SWAT database. The ArcSWAT model was established in the Changle River after the calibrating and validating procedures of the model parameters. Based on the validated SWAT model, the contributions of different nitrogen sources to river TN loading were quantified, and spatial-temporal distributions of NPS nitrogen export to rivers were addressed. The results showed that in the Changle River watershed, Nitrogen fertilizer, nitrogen air deposition and nitrogen soil pool were the prominent pollution sources, which contributed 35%, 32% and 25% to the river TN loading, respectively. There were spatial-temporal variations in the critical sources for NPS TN export to the river. Natural sources, such as soil nitrogen pool and atmospheric nitrogen deposition, should be targeted as the critical sources for river TN pollution during the rainy seasons. Chemical nitrogen fertilizer application should be targeted as the critical sources for river TN pollution during the crop growing season. Chemical nitrogen fertilizer application, soil nitrogen pool and atmospheric nitrogen deposition were the main sources for TN exported from the garden plot, forest and residential land, respectively. However, they were the main sources for TN exported both from the upland and paddy field. These results revealed that NPS pollution controlling rules should focus on the spatio-temporal distribution of NPS pollution sources.

Mechanical signals in plant development: a new method for single cell studies

NASA Technical Reports Server (NTRS)

Lynch, T. M.; Lintilhac, P. M.

1997-01-01

Cell division, which is critical to plant development and morphology, requires the orchestration of hundreds of intracellular processes. In the end, however, cells must make critical decisions, based on a discrete set of mechanical signals such as stress, strain, and shear, to divide in such a way that they will survive the mechanical loads generated by turgor pressure and cell enlargement within the growing tissues. Here we report on a method whereby tobacco protoplasts swirled into a 1.5% agarose entrapment medium will survive and divide. The application of a controlled mechanical load to agarose blocks containing protoplasts orients the primary division plane of the embedded cells. Photoelastic analysis of the agarose entrapment medium can identify the lines of principal stress within the agarose, confirming the hypothesis that cells divide either parallel or perpendicular to the principal stress tensors. The coincidence between the orientation of the new division wall and the orientation of the principal stress tensors suggests that the perception of mechanical stress is a characteristic of individual plant cells. The ability of a cell to determine a shear-free orientation for a new partition wall may be related to the applied load through the deformation of the matrix material. In an isotropic matrix a uniaxial load will produce a rotationally symmetric strain field, which will define a shear-free plane. Where high stress intensities combine with the loading geometry to produce multiaxial loads there will be no axis of rotational symmetry and hence no shear free plane. This suggests that two mechanisms may be orienting the division plane, one a mechanism that works in rotationally symmetrical fields, yielding divisions perpendicular to the compressive tensor, parallel to the long axis of the cell, and one in asymmetric fields, yielding divisions parallel to the short axis of the cell and the compressive tensor.

New evaluation parameter for wearable thermoelectric generators

NASA Astrophysics Data System (ADS)

Wijethunge, Dimuthu; Kim, Woochul

2018-04-01

Wearable devices constitute a key application area for thermoelectric devices. However, owing to new constraints in wearable applications, a few conventional device optimization techniques are not appropriate and material evaluation parameters, such as figure of merit (zT) and power factor (PF), tend to be inadequate. We illustrated the incompleteness of zT and PF by performing simulations and considering different thermoelectric materials. The results indicate a weak correlation between device performance and zT and PF. In this study, we propose a new evaluation parameter, zTwearable, which is better suited for wearable applications compared to conventional zT. Owing to size restrictions, gap filler based device optimization is extremely critical in wearable devices. With respect to the occasions in which gap fillers are used, expressions for power, effective thermal conductivity (keff), and optimum load electrical ratio (mopt) are derived. According to the new parameters, the thermal conductivity of the material has become much more critical now. The proposed new evaluation parameter, namely, zTwearable, is extremely useful in the selection of an appropriate thermoelectric material among various candidates prior to the commencement of the actual design process.

Lubricant evaluation of the alpha and beta joints, phase 2

NASA Technical Reports Server (NTRS)

Kannel, J. W.; Stockwell, R. D.

1992-01-01

A research study was conducted to evaluate dry film lubrication of long life space components such as the alpha and beta joints of the Space Station. The problem addressed in the report pertains to the longevity of sputtered MoS2 or ion plated lead films in a rolling contact environment. A special technique was devised for the experiments, which incorporated a coated ball cyclically loaded against a flat plate. At fixed intervals the surface of the coating was photographed at 100X magnification. By computer scanning the photographs, the rate of coating loss was determined. Experimental variables include load and surface finish of the plate. A theory was developed to analyze the state of stress between ball and flat. The stress condition in the ball apparatus was related to the state of stress under rolling contact conditions. Based on the experiments life appeared to decrease with increasing load and increasing surface roughness. An ion plated lead film gave better life than a sputtered MoS2 film. However, by keeping the interfacial shear stress at a low level, adequate coating life was achieved for either coating. For the lead film, the critical stress was about 0.19 GPa (28 ksi). The study dealt only with mechanical wear. Before a coating is selected for a critical space application, other factors such as reaction with atomic oxygen must also be considered.

Atmospheric deposition and ozone levels in Swiss forests: are critical values exceeded?

PubMed

Waldner, Peter; Schaub, Marcus; Graf Pannatier, Elisabeth; Schmitt, Maria; Thimonier, Anne; Walthert, Lorenz

2007-05-01

Air pollution affects forest health through atmospheric deposition of acidic and nitrogen compounds and elevated levels of tropospheric ozone (O3). In 1985, a monitoring network was established across Europe and various research efforts have since been undertaken to define critical values. We measured atmospheric deposition of acidity and nitrogen as well as ambient levels of O3 on 12, 13, and 14 plots, respectively, in the framework of the Swiss Long-Term Forest Ecosystem Research (LWF) in the period from 1995 to 2002. We estimated the critical loads of acidity and of nitrogen, using the steady state mass balance approach, and calculated the critical O3 levels using the AOT40 approach. The deposition of acidity exceeded the critical loads on 2 plots and almost reached them on 4 plots. The median of the measured molar ratio of base nutrient cations to total dissolved aluminium (Bc/Al) in the soil solution was higher than the critical value of 1 for all depths, and also at the plots with an exceedance of the critical load of acidity. For nitrogen, critical loads were exceeded on 8 plots and deposition likely represents a long-term ecological risk on 3 to 10 plots. For O3, exceedance of critical levels was recorded on 12 plots, and led to the development of typical O3-induced visible injury on trees and shrubs, but not for all plots due to (1) the site specific composition of O3 sensitive and tolerant plant species, and (2) the influence of microclimatic site conditions on the stomatal behaviour, i.e., O3 uptake.

Dynamic Tensile Loading Improves the Functional Properties of Mesenchymal Stem Cell-Laden Nanofiber-Based Fibrocartilage

PubMed Central

Baker, Brendon M.; Shah, Roshan P.; Huang, Alice H.

2011-01-01

Fibrocartilaginous tissues such as the meniscus serve critical load-bearing roles, relying on arrays of collagen fibers to resist tensile loads experienced with normal activity. As these structures are frequently injured and possess limited healing capacity, there exists great demand for tissue-engineered replacements. Toward recreating the structural features of these anisotropic tissues in vitro, we employ scaffolds composed of co-aligned nanofibers that direct mesenchymal stem cell (MSC) orientation and the formation of organized extracellular matrix (ECM). Concomitant with ECM synthesis, the mechanical properties of constructs increase with free-swelling culture, but ultimately failed to achieve equivalence with meniscal fibrocartilage. As mechanical forces are essential to the development and maintenance of musculoskeletal tissues, this work examined the effect of cyclic tensile loading on MSC-laden nanofibrous constructs. We hypothesized that loading would modulate the transcriptional behavior of MSCs, spur the deposition of ECM, and lead to enhancements in construct mechanical properties compared to free-swelling controls. Fiber-aligned scaffolds were seeded with MSCs and dynamically loaded daily in tension or maintained as nonloaded controls for 4 weeks. With mechanical stimulation, fibrous gene expression increased, collagen deposition increased, and the tensile modulus increased by 16% relative to controls. These results show that dynamic tensile loading enhances the maturation of MSC-laden aligned nanofibrous constructs, suggesting that recapitulation of the structural and mechanical environment of load-bearing tissues results in increases in functional properties that can be exploited for tissue engineering applications. PMID:21247342

Dynamic tensile loading improves the functional properties of mesenchymal stem cell-laden nanofiber-based fibrocartilage.

PubMed

Baker, Brendon M; Shah, Roshan P; Huang, Alice H; Mauck, Robert L

2011-05-01

Fibrocartilaginous tissues such as the meniscus serve critical load-bearing roles, relying on arrays of collagen fibers to resist tensile loads experienced with normal activity. As these structures are frequently injured and possess limited healing capacity, there exists great demand for tissue-engineered replacements. Toward recreating the structural features of these anisotropic tissues in vitro, we employ scaffolds composed of co-aligned nanofibers that direct mesenchymal stem cell (MSC) orientation and the formation of organized extracellular matrix (ECM). Concomitant with ECM synthesis, the mechanical properties of constructs increase with free-swelling culture, but ultimately failed to achieve equivalence with meniscal fibrocartilage. As mechanical forces are essential to the development and maintenance of musculoskeletal tissues, this work examined the effect of cyclic tensile loading on MSC-laden nanofibrous constructs. We hypothesized that loading would modulate the transcriptional behavior of MSCs, spur the deposition of ECM, and lead to enhancements in construct mechanical properties compared to free-swelling controls. Fiber-aligned scaffolds were seeded with MSCs and dynamically loaded daily in tension or maintained as nonloaded controls for 4 weeks. With mechanical stimulation, fibrous gene expression increased, collagen deposition increased, and the tensile modulus increased by 16% relative to controls. These results show that dynamic tensile loading enhances the maturation of MSC-laden aligned nanofibrous constructs, suggesting that recapitulation of the structural and mechanical environment of load-bearing tissues results in increases in functional properties that can be exploited for tissue engineering applications.

The mechanisms of plastic strain accommodation and post critical behavior of heterogeneous reactive composites subject to dynamic loading

NASA Astrophysics Data System (ADS)

Olney, Karl L.

The dynamic behavior of granular/porous and laminate reactive materials is of interest due to their practical applications; reactive structural components, reactive fragments, etc. The mesostructural properties control meso- and macro-scale dynamic behavior of these heterogeneous composites including the behavior during the post-critical stage of deformation. They heavily influence mechanisms of fragment generation and the in situ development of local hot spots, which act as sites of ignition in these materials. This dissertation concentrates on understanding the mechanisms of plastic strain accommodation in two representative reactive material systems with different heterogeneous mesostructrues: Aluminum-Tungsten granular/porous and Nickel-Aluminum laminate composites. The main focus is on the interpretation of results of the following dynamic experiments conducted at different strain and strain rates: drop weight tests, explosively expanded ring experiments, and explosively collapsed thick walled cylinder experiments. Due to the natural limitations in the evaluation of the mesoscale behavior of these materials experimentally and the large variation in the size scales between the mesostructural level and the sample, it is extremely difficult, if not impossible, to examine the mesoscale behavior in situ. Therefore, numerical simulations of the corresponding experiments are used as the main tool to explore material behavior at the mesoscale. Numerical models were developed to elucidate the mechanisms of plastic strain accommodation and post critical behavior in these heterogeneous composites subjected to dynamic loading. These simulations were able to reproduce the qualitative and quantitative features that were observable in the experiments and provided insight into the evolution of the mechanisms of plastic strain accommodation and post critical behavior in these materials with complex mesotructure. Additionally, these simulations provided a framework to examine the influence of various mesoscale properties such as the bonding of interfaces, the role of material properties, and the influence of mesoscale geometry. The results of this research are helpful in the design of material mesotructures conducive to the desirable behavior under dynamic loading.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bouchard, P.J.

A forthcoming revision to the R6 Leak-before-Break Assessment Procedure is briefly described. Practical application of the LbB concepts to safety-critical nuclear plant is illustrated by examples covering both low temperature and high temperature (>450{degrees}C) operating regimes. The examples highlight a number of issues which can make the development of a satisfactory LbB case problematic: for example, coping with highly loaded components, methodology assumptions and the definition of margins, the effect of crack closure owing to weld residual stresses, complex thermal stress fields or primary bending fields, the treatment of locally high stresses at crack intersections with free surfaces, the choicemore » of local limit load solution when predicting ligament breakthrough, and the scope of calculations required to support even a simplified LbB case for high temperature steam pipe-work systems.« less

Minimizing masses in explosively driven two-shockwave physics applications

NASA Astrophysics Data System (ADS)

Buttler, William; Cherne, Frank; Furlanetto, Michael; Payton, Jeremy; Stone, Joseph; Tabaka, Leonard; Vincent, Samuel

2015-06-01

We have experimentally investigated different two-shockwave high-explosives (HE) physics package designs to maximize the variability of the second shockwave peak stress, while minimizing the total HE load of the physics tool. A critical requirement is to also have a large radial diameter of the second shockwave to maintain its value as an HE driven two-shockwave drive. We have previously shown that we could vary the peak-stress of the second-shockwave with a 76 mm diameter HE lens driving different composite boosters of PBX 9501 and TNT. Here we report on our results with a 56- and 50-mm diameter HE lens driving Baritol. The results indicate that the 56-mm diameter HE lens works well, as does the Baritol, giving total HE loads of about 250 mg TNT equivalent explosives.

Onset of frictional sliding of rubber–glass contact under dry and lubricated conditions

PubMed Central

Tuononen, Ari J.

2016-01-01

Rubber friction is critical in many applications ranging from automotive tyres to cylinder seals. The process where a static rubber sample transitions to frictional sliding is particularly poorly understood. The experimental and simulation results in this paper show a completely different detachment process from the static situation to sliding motion under dry and lubricated conditions. The results underline the contribution of the rubber bulk properties to the static friction force. In fact, simple Amontons’ law is sufficient as a local friction law to produce the correct detachment pattern when the rubber material and loading conditions are modelled properly. Simulations show that micro-sliding due to vertical loading can release initial shear stresses and lead to a high static/dynamic friction coefficient ratio, as observed in the measurements. PMID:27291939

Technology and operational considerations for low-heat-rate trajectories. [of future winged earth reentry vehicles

NASA Technical Reports Server (NTRS)

Wurster, K. E.; Eldred, C. H.

1979-01-01

A broad parametric study which examines several critical aspects of low-heat-rate entry trajectories is performed. Low planform loadings associated with future winged earth-entry vehicles coupled with the potential application of metallic thermal protection systems (TPS) suggest that such trajectories are of particular interest. Studied are three heating conditions - reference, stagnation, and windward centerline, for both laminar and turbulent flow; configuration-related factors including planform loading and hypersonic angle of attack; and mission-related factors such as cross-range and orbit inclination. Results indicate benefits in the design of TPS to be gained by utilizing moderate angles of attack as opposed to high-lift coefficient, high angles of attack, during entry. An assessment of design and technology implications is made.

Dynamic stability of unidirectional fiber-reinforced viscoelastic composite plates

NASA Technical Reports Server (NTRS)

Chandiramani, N. K.; Librescu, L.

1989-01-01

This paper deals with a dynamic stability analysis of unidirectional fiber-reinforced composite viscoelastic plates subjected to compressive edge loads. The integrodifferential equations governing the stability problem are obtained by using, in conjunction with a Boltzmann hereditary constitutive law for a three-dimensional viscoelastic medium, a higher-order shear deformation theory of orthotropic plates. Such a theory incorporates transverse shear deformation, transverse normal stress, and rotatory inertia effects. The solution of the stability problem as considered within this paper concerns the determination of the critical in-plane edge loads yielding the asymptotic instability. Numerical applications, based on material properties derived within the framework of Aboudi's micromechanical model, are presented and pertinent conclusions concerning the nature of the loss of stability and the influence of various parameters are outlined.

Filament instability under constant loads

NASA Astrophysics Data System (ADS)

Monastra, A. G.; Carusela, M. F.; D’Angelo, M. V.; Bruno, L.

2018-04-01

Buckling of semi-flexible filaments appears in different systems and scales. Some examples are: fibers in geophysical applications, microtubules in the cytoplasm of eukaryotic cells and deformation of polymers freely suspended in a flow. In these examples, instabilities arise when a system’s parameter exceeds a critical value, being the Euler force the most known. However, the complete time evolution and wavelength of buckling processes are not fully understood. In this work we solve analytically the time evolution of a filament under a constant compressive force in the small amplitude approximation. This gives an insight into the variable force scenario in terms of normal modes. The evolution is highly sensitive to the initial configuration and to the magnitude of the compressive load. This model can be a suitable approach to many different real situations.

Experimental Study on the Anisotropic Stress-Strain Behavior of Polycrystalline Ni-Mn-Ga in Directional Solidification

NASA Astrophysics Data System (ADS)

Teng, Yao; Shi, Tao; Zhu, Yuping; Li, Zongbin; Deng, Tao; Bai, Guonan

2016-03-01

A polycrystalline Ni-Mn-Ga ferromagnetic shape memory alloy produced by directional solidification is the subject of this research paper. The compressive stress-strain curves of the material for different cutting angles to the solidification direction are tested. The martensite Young's modulus, macroscopic reorientation strain, and phase transition critical stress are analyzed experimentally. The results show that mechanical behaviors in the loading-unloading cycle of the material present nonlinear and anisotropic characteristics, which are all closely related to the material's orientation to the solidification direction. The martensite Young's modulus, macroscopic reorientation strain, and phase transition critical stress achieve maximum values in the solidification direction. A 50° orientation to the solidification direction is the cut-off direction of the mechanical properties, where the martensite Young's modulus and reorientation start critical stress reach minimum values. The present study is expected to provide sound guidance for practical applications.

Atmospheric nitrogen deposition to China: a model analysis on nitrogen budget and critical load exceedance

NASA Astrophysics Data System (ADS)

Zhao, Y.; Zhang, L.; Chen, Y.; Liu, X.; Xu, W.; Pan, Y.; Duan, L.

2016-12-01

We present a national-scale model analysis of the sources and processes of inorganic nitrogen deposition over China using the GEOS-Chem model at 1/2°×1/3° horizontal resolution. Averaged model results for 2008-2012 are evaluated with an ensemble of surface measurements of nitrogen wet deposition flux and concentration, and satellite measurements of tropospheric NO2 columns. Annual inorganic nitrogen deposition fluxes are shown to be generally less than 10 kg N ha-1 a-1 in the western China, 15-50 kg N ha-1 a-1 in the eastern China, and 15.6 kg N ha-1 a-1 averaged over China. The model simulates an annual total deposition flux of 16.4 Tg N to China, with 10.3 Tg N (63%) from reduced nitrogen (NHx) and 6.2 Tg N from oxidized nitrogen (NOy). Domestic anthropogenic sources contribute 86% of the total deposition; foreign anthropogenic sources 7% and natural sources 7%. Annually 23% of domestically emitted NH3 and 36% for NOx are exported out of China. We also find while nitrogen deposition to China is comparable to the nitrogen input from fertilizer application (16.5 Tg N a-1) on the national scale, it is much more widely distributed spatially. The deposition flux is also much higher than natural biological fixation (7.3 Tg N a-1). A comparison with estimates of nitrogen critical load for eutrophication indicates that about 40% of the land over China faces nitrogen critical load exceedances. However, 45% of the exceeding areas, mainly in Beijing-Tianjin-Hebei, Central China, East China, and South China, will not occur in the absence of nitrogen deposition, demonstrating the necessity of nitrogen emission controls to avoid potential negative ecological effects over these areas.

Development and validation of a new kind of coupling element for wheel-hub motors

NASA Astrophysics Data System (ADS)

Perekopskiy, Sergey; Kasper, Roland

2018-05-01

For the automotive industry, electric powered vehicles are becoming an increasingly relevant factor in the competition against climate change. Application of one special example - a wheel-hub motor, for electric powered vehicle can support this challenge. Patented slotless air gap winding invented at the chair of mechatronics of the Otto von Guericke University Magdeburg has great application potential in constantly growing e-mobility field, especially for wheel-hub motors based on this technology due to its advantages, such as a high gravimetric power density and high efficiency. However, advantages of this technology are decreased by its sensibility to the loads out of driving maneuvers by dimensional variations of air gap consistency. This article describes the development and validation of a coupling element for the designed wheel-hub motor. To find a suitable coupling concept first the assembly structure of the motor was analyzed and developed design of the coupling element was checked. Based on the geometry of the motor and wheel a detailed design of the coupling element was generated. The analytical approach for coupling element describes a potential of the possible loads on the coupling element. The FEM simulation of critical load cases for the coupling element validated results of the analytical approach.

Simulating Fatigue Crack Growth in Spiral Bevel Gears

NASA Technical Reports Server (NTRS)

Spievak, Lisa E.; Wawrzynek, Paul A.; Ingraffea, Anthony R.

2000-01-01

The majority of helicopter transmission systems utilize spiral bevel gears to convert the horizontal power from the engine into vertical power for the rotor. Due to the cyclical loading on a gear's tooth, fatigue crack propagation can occur. In rotorcraft applications, a crack's trajectory determines whether the gear failure will be benign or catastrophic for the aircraft. As a result, the capability to predict crack growth in gears is significant. A spiral bevel gear's complex shape requires a three dimensional model of the geometry and cracks. The boundary element method in conjunction with linear elastic fracture mechanics theories is used to predict arbitrarily shaped three dimensional fatigue crack trajectories in a spiral bevel pinion under moving load conditions. The predictions are validated by comparison to experimental results. The sensitivity of the predictions to variations in loading conditions and crack growth rate model parameters is explored. Critical areas that must be understood in greater detail prior to predicting more accurate crack trajectories and crack growth rates in three dimensions are identified.

Critical Current of Superconducting Rutherford Cable in High Magnetic Fields with Transverse Pressure

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dietderich, D.R.; Scanlan, R.M.; Walsh, R.P.

For high energy physics applications superconducting cables are subjected to large stresses and high magnetic fields during service. It is essential to know how these cables perform in these operating conditions. A loading fixture capable of applying loads of up to 700 kN has been developed by NHMFL for LBNL. This fixture permits uniform loading of straight cables over a 122 mm length in a split-pair solenoid in fields up to 12 T at 4.2 K. The first results from this system for Rutherford cables of internal-tin and modified jelly roll strand of Nb{sub 3}Sn produced by IGC and TWCmore » showed that little permanent degradation occurs up to 210 MPa. However, the cable made from internal-tin strand showed a 40% reduction in K{sub c} at 11T and 210 MPa while a dable made from modified jelly roll material showed only a 15% reduction in I{sub c} at 11T and 185 MPa.« less

Leucine/Pd-loaded (5,5) single-walled carbon nanotube matrix as a novel nanobiosensors for in silico detection of protein.

PubMed

Yoosefian, Mehdi; Etminan, Nazanin

2018-06-01

We have designed a novel nanobiosensor for in silico detecting proteins based on leucine/Pd-loaded single-walled carbon nanotube matrix. Density functional theory at the B3LYP/6-31G (d) level of theory was realized to analyze the geometrical and electronic structure of the proposed nanobiosensor. The solvent effects were investigated using the Tomasi's polarized continuum model. Atoms-in-molecules theory was used to study the nature of interactions by calculating the electron density ρ(r) and Laplacian at the bond critical points. Natural bond orbital analysis was performed to achieve a deep understanding of the nature of the interactions. The biosensor has potential application for high sensitive and rapid response to protein due to the chemical adsorption of L-leucine amino acid onto Pd-loaded single-walled carbon nanotube and reactive functional groups that can incorporate in hydrogen binding, hydrophobic interactions and van der Waals forces with the protein surface in detection process.

Logistics Modeling for Lunar Exploration Systems

NASA Technical Reports Server (NTRS)

Andraschko, Mark R.; Merrill, R. Gabe; Earle, Kevin D.

2008-01-01

The extensive logistics required to support extended crewed operations in space make effective modeling of logistics requirements and deployment critical to predicting the behavior of human lunar exploration systems. This paper discusses the software that has been developed as part of the Campaign Manifest Analysis Tool in support of strategic analysis activities under the Constellation Architecture Team - Lunar. The described logistics module enables definition of logistics requirements across multiple surface locations and allows for the transfer of logistics between those locations. A key feature of the module is the loading algorithm that is used to efficiently load logistics by type into carriers and then onto landers. Attention is given to the capabilities and limitations of this loading algorithm, particularly with regard to surface transfers. These capabilities are described within the context of the object-oriented software implementation, with details provided on the applicability of using this approach to model other human exploration scenarios. Some challenges of incorporating probabilistics into this type of logistics analysis model are discussed at a high level.

Development of a Practical Methodology for Elastic-Plastic and Fully Plastic Fatigue Crack Growth

NASA Technical Reports Server (NTRS)

McClung, R. C.; Chell, G. G.; Lee, Y. -D.; Russell, D. A.; Orient, G. E.

1999-01-01

A practical engineering methodology has been developed to analyze and predict fatigue crack growth rates under elastic-plastic and fully plastic conditions. The methodology employs the closure-corrected effective range of the J-integral, delta J(sub eff) as the governing parameter. The methodology contains original and literature J and delta J solutions for specific geometries, along with general methods for estimating J for other geometries and other loading conditions, including combined mechanical loading and combined primary and secondary loading. The methodology also contains specific practical algorithms that translate a J solution into a prediction of fatigue crack growth rate or life, including methods for determining crack opening levels, crack instability conditions, and material properties. A critical core subset of the J solutions and the practical algorithms has been implemented into independent elastic-plastic NASGRO modules. All components of the entire methodology, including the NASGRO modules, have been verified through analysis and experiment, and limits of applicability have been identified.

Development of a Practical Methodology for Elastic-Plastic and Fully Plastic Fatigue Crack Growth

NASA Technical Reports Server (NTRS)

McClung, R. C.; Chell, G. G.; Lee, Y.-D.; Russell, D. A.; Orient, G. E.

1999-01-01

A practical engineering methodology has been developed to analyze and predict fatigue crack growth rates under elastic-plastic and fully plastic conditions. The methodology employs the closure-corrected effective range of the J-integral, (Delta)J(sub eff), as the governing parameter. The methodology contains original and literature J and (Delta)J solutions for specific geometries, along with general methods for estimating J for other geometries and other loading conditions, including combined mechanical loading and combined primary and secondary loading. The methodology also contains specific practical algorithms that translate a J solution into a prediction of fatigue crack growth rate or life, including methods for determining crack opening levels, crack instability conditions, and material properties. A critical core subset of the J solutions and the practical algorithms has been implemented into independent elastic-plastic NASGRO modules. All components of the entire methodology, including the NASGRO modules, have been verified through analysis and experiment, and limits of applicability have been identified.

High Temperature Solid Lubricant Materials for Heavy Duty and Advanced Heat Engines

NASA Technical Reports Server (NTRS)

Dellacorte, C.; Wood, J. C.

1994-01-01

Advanced engine designs incorporate higher mechanical and thermal loading to achieve efficiency improvements. This approach often leads to higher operating temperatures of critical sliding elements (e.g. piston ring/cylinder wall contacts and valve guides) which compromise the use of conventional and even advanced synthetic liquid lubricants. For these applications solid lubricants must be considered. Several novel solid lubricant composites and coatings designated PS/PM200 have been employed to dry and marginally oil lubricated contacts in advanced heat engines. These applications include cylinder kits of heavy duty diesels, and high temperature Stirling engines, sidewall seals of rotary engines, and various exhaust valve and exhaust component applications. This paper describes the tribological and thermophysical properties of these tribomaterials and reviews the results of applying them to engine applications. Other potential tribological materials and applications are also discussed with particular emphasis on heavy duty and advanced heat engines.

Dynamic strength of cylindrical fiber-glass shells and basalt plastic shells under multiple explosive loading

NASA Astrophysics Data System (ADS)

Syrunin, M. A.; Fedorenko, A. G.

2006-08-01

We have shown experimentally that, for cylindrical shells made of oriented fiberglass platic and basalt plastic there exists a critical level of deformations, at which a structure sustains a given number of explosions from the inside. The magnitude of critical deformation for cylindrical fiberglass shells depends linearly on the logarithm of the number of loads that cause failure. For a given type of fiberglass, there is a limiting level of explosive action, at which the number of loads that do not lead to failure can be sufficiently large (more than ˜ 102). This level is attained under loads, which are an order of magnitude lower than the limiting loads under a single explosive action. Basalt plastic shells can be repeatedly used even at the loads, which cause deformation by ˜ 30-50% lower than the safe value ˜ 3.3.5% at single loading.

Acoustic bed velocity and bed load dynamics in a large sand bed river

USGS Publications Warehouse

Gaeuman, D.; Jacobson, R.B.

2006-01-01

Development of a practical technology for rapid quantification of bed load transport in large rivers would represent a revolutionary advance for sediment monitoring and the investigation of fluvial dynamics. Measurement of bed load motion with acoustic Doppler current profiles (ADCPs) has emerged as a promising approach for evaluating bed load transport. However, a better understanding of how ADCP data relate to conditions near the stream bed is necessary to make the method practical for quantitative applications. In this paper, we discuss the response of ADCP bed velocity measurements, defined as the near-bed sediment velocity detected by the instrument's bottom-tracking feature, to changing sediment-transporting conditions in the lower Missouri River. Bed velocity represents a weighted average of backscatter from moving bed load particles and spectral reflections from the immobile bed. The ratio of bed velocity to mean bed load particle velocity depends on the concentration of the particles moving in the bed load layer, the bed load layer thickness, and the backscatter strength from a unit area of moving particles relative to the echo strength from a unit area of unobstructed bed. A model based on existing bed load transport theory predicted measured bed velocities from hydraulic and grain size measurements with reasonable success. Bed velocities become more variable and increase more rapidly with shear stress when the transport stage, defined as the ratio of skin friction to the critical shear stress for particle entrainment, exceeds a threshold of about 17. This transition in bed velocity response appears to be associated with the appearance of longer, flatter bed forms at high transport stages.

Bone quality and the immediate loading of implants-critical aspects based on literature, research, and clinical experience.

PubMed

Romanos, Georgios E

2009-06-01

Immediate loading of oral implants has been extensively described in the international literature and the requirements for long-term success are evaluated. The author presents here the critical aspects of the criteria for success as well as describes the characteristics of an implant macro- and microdesign for immediate loading to control the periimplant crestal bone loss and secure the long-term stability. Information from the literature and the clinical experience will be presented.

Some issues in numerical simulation of nonlinear structural response

NASA Technical Reports Server (NTRS)

Hibbitt, H. D.

1989-01-01

The development of commercial finite element software is addressed. This software provides practical tools that are used in an astonishingly wide range of engineering applications that include critical aspects of the safety evaluation of nuclear power plants or of heavily loaded offshore structures in the hostile environments of the North Sea or the Arctic, major design activities associated with the development of airframes for high strength and minimum weight, thermal analysis of electronic components, and the design of sports equipment. In the more advanced application areas, the effectiveness of the product depends critically on the quality of the mechanics and mechanics related algorithms that are implemented. Algorithmic robustness is of primary concern. Those methods that should be chosen will maximize reliability with minimal understanding on the part of the user. Computational efficiency is also important because there are always limited resources, and hence problems that are too time consuming or costly. Finally, some areas where research work will provide new methods and improvements is discussed.

Ceramic Matrix Composites (CMC) Life Prediction Method Development

NASA Technical Reports Server (NTRS)

Levine, Stanley R.; Calomino, Anthony M.; Ellis, John R.; Halbig, Michael C.; Mital, Subodh K.; Murthy, Pappu L.; Opila, Elizabeth J.; Thomas, David J.; Thomas-Ogbuji, Linus U.; Verrilli, Michael J.

2000-01-01

Advanced launch systems (e.g., Reusable Launch Vehicle and other Shuttle Class concepts, Rocket-Based Combine Cycle, etc.), and interplanetary vehicles will very likely incorporate fiber reinforced ceramic matrix composites (CMC) in critical propulsion components. The use of CMC is highly desirable to save weight, to improve reuse capability, and to increase performance. CMC candidate applications are mission and cycle dependent and may include turbopump rotors, housings, combustors, nozzle injectors, exit cones or ramps, and throats. For reusable and single mission uses, accurate prediction of life is critical to mission success. The tools to accomplish life prediction are very immature and not oriented toward the behavior of carbon fiber reinforced silicon carbide (C/SiC), the primary system of interest for a variety of space propulsion applications. This paper describes an approach to satisfy the need to develop an integrated life prediction system for CMC that addresses mechanical durability due to cyclic and steady thermomechanical loads, and takes into account the impact of environmental degradation.

Lichen-based critical loads for atmospheric nitrogen deposition in Western Oregon and Washington forests, USA

Treesearch

Linda H. Geiser; Sarah E. Jovan; Doug A. Glavich; Matthew K. Porter

2010-01-01

Critical loads (CLs) define maximum atmospheric deposition levels apparently preventative of ecosystem harm. We present first nitrogen CLs for northwestern North America's maritime forests. Using multiple linear regression, we related epiphytic-macrolichen community composition to: 1) wet deposition from the National Atmospheric Deposition Program, 2) wet, dry,...

Active controls technology to maximize structural efficiency

NASA Technical Reports Server (NTRS)

Hoy, J. M.; Arnold, J. M.

1978-01-01

The implication of the dependence on active controls technology during the design phase of transport structures is considered. Critical loading conditions are discussed along with probable ways of alleviating these loads. Why fatigue requirements may be critical and can only be partially alleviated is explained. The significance of certain flutter suppression system criteria is examined.

Use of combined biogeochemical model approaches and empirical data to assess critical loads of nitrogen

Treesearch

Mark Fenn; Charles Driscoll; Quingtao Zhou; Leela Rao; Thomas Meixner; Edith Allen; Fengming Yuan; Timothy Sullivan

2015-01-01

Empirical and dynamic biogeochemical modelling are complementary approaches for determining the critical load (CL) of atmospheric nitrogen (N) or other constituent deposition that an ecosystem can tolerate without causing ecological harm. The greatest benefits are obtained when these approaches are used in combination. Confounding environmental factors can complicate...

Innovative applications of artificial intelligence

NASA Astrophysics Data System (ADS)

Schorr, Herbert; Rappaport, Alain

Papers concerning applications of artificial intelligence are presented, covering applications in aerospace technology, banking and finance, biotechnology, emergency services, law, media planning, music, the military, operations management, personnel management, retail packaging, and manufacturing assembly and design. Specific topics include Space Shuttle telemetry monitoring, an intelligent training system for Space Shuttle flight controllers, an expert system for the diagnostics of manufacturing equipment, a logistics management system, a cooling systems design assistant, and a knowledge-based integrated circuit design critic. Additional topics include a hydraulic circuit design assistant, the use of a connector assembly specification expert system to harness detailed assembly process knowledge, a mixed initiative approach to airlift planning, naval battle management decision aids, an inventory simulation tool, a peptide synthesis expert system, and a system for planning the discharging and loading of container ships.

The dynamic failure behavior of tungsten heavy alloys subjected to transverse loads

NASA Astrophysics Data System (ADS)

Tarcza, Kenneth Robert

Tungsten heavy alloys (WHA), a category of particulate composites used in defense applications as kinetic energy penetrators, have been studied for many years. Even so, their dynamic failure behavior is not fully understood and cannot be predicted by numerical models presently in use. In this experimental investigation, a comprehensive understanding of the high-rate transverse-loading fracture behavior of WHA has been developed. Dynamic fracture events spanning a range of strain rates and loading conditions were created via mechanical testing and used to determine the influence of surface condition and microstructure on damage initiation, accumulation, and sample failure under different loading conditions. Using standard scanning electron microscopy metallographic and fractographic techniques, sample surface condition is shown to be extremely influential to the manner in which WHA fails, causing a fundamental change from externally to internally nucleated failures as surface condition is improved. Surface condition is characterized using electron microscopy and surface profilometry. Fracture surface analysis is conducted using electron microscopy, and linear elastic fracture mechanics is used to understand the influence of surface condition, specifically initial flaw size, on sample failure behavior. Loading conditions leading to failure are deduced from numerical modeling and experimental observation. The results highlight parameters and considerations critical to the understanding of dynamic WHA fracture and the development of dynamic WHA failure models.

A testing platform for durability studies of polymers and fiber-reinforced polymer composites under concurrent hygrothermo-mechanical stimuli.

PubMed

Gomez, Antonio; Pires, Robert; Yambao, Alyssa; La Saponara, Valeria

2014-12-11

The durability of polymers and fiber-reinforced polymer composites under service condition is a critical aspect to be addressed for their robust designs and condition-based maintenance. These materials are adopted in a wide range of engineering applications, from aircraft and ship structures, to bridges, wind turbine blades, biomaterials and biomedical implants. Polymers are viscoelastic materials, and their response may be highly nonlinear and thus make it challenging to predict and monitor their in-service performance. The laboratory-scale testing platform presented herein assists the investigation of the influence of concurrent mechanical loadings and environmental conditions on these materials. The platform was designed to be low-cost and user-friendly. Its chemically resistant materials make the platform adaptable to studies of chemical degradation due to in-service exposure to fluids. An example of experiment was conducted at RT on closed-cell polyurethane foam samples loaded with a weight corresponding to ~50% of their ultimate static and dry load. Results show that the testing apparatus is appropriate for these studies. Results also highlight the larger vulnerability of the polymer under concurrent loading, based on the higher mid-point displacements and lower residual failure loads. Recommendations are made for additional improvements to the testing apparatus.

A Testing Platform for Durability Studies of Polymers and Fiber-reinforced Polymer Composites under Concurrent Hygrothermo-mechanical Stimuli

PubMed Central

Gomez, Antonio; Pires, Robert; Yambao, Alyssa; La Saponara, Valeria

2014-01-01

The durability of polymers and fiber-reinforced polymer composites under service condition is a critical aspect to be addressed for their robust designs and condition-based maintenance. These materials are adopted in a wide range of engineering applications, from aircraft and ship structures, to bridges, wind turbine blades, biomaterials and biomedical implants. Polymers are viscoelastic materials, and their response may be highly nonlinear and thus make it challenging to predict and monitor their in-service performance. The laboratory-scale testing platform presented herein assists the investigation of the influence of concurrent mechanical loadings and environmental conditions on these materials. The platform was designed to be low-cost and user-friendly. Its chemically resistant materials make the platform adaptable to studies of chemical degradation due to in-service exposure to fluids. An example of experiment was conducted at RT on closed-cell polyurethane foam samples loaded with a weight corresponding to ~50% of their ultimate static and dry load. Results show that the testing apparatus is appropriate for these studies. Results also highlight the larger vulnerability of the polymer under concurrent loading, based on the higher mid-point displacements and lower residual failure loads. Recommendations are made for additional improvements to the testing apparatus. PMID:25548950

Modeling Load Dynamics to Support Resiliency-based Operations in Low-Inertia Microgrids

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tuffner, Francis K.; Schneider, Kevin P.; Hansen, Jacob

Microgrids have repeatedly demonstrated the ability to provide uninterrupted service to critical end-use loads during normal outages, severe weather events, and natural disasters. While their ability to provide critical services is well documented, microgrids present a more dynamic operational environment than grid-connected distribution systems. The electrodynamics of a microgrid are commonly driven by the high inertia of rotating generators, which are common in many microgrids. In such high-inertia systems, the impact of end-use load electromechanical dynamics are often not examined. However, with the increased penetration of inverter-based generation with little or no inertia, it is necessary to consider the impactmore » that the dynamics of the end-use loads have on the operations of microgrids, particularly for a resiliency-based operation. These operations include, but are not limited to, switching operations, loss of generating units, and the starting of induction motors. This paper examines the importance of including multi-state electromechanical dynamic models of the end-use load when evaluating the operations of low inertia microgrids, and shows that by properly representing their behavior, it is possible to cost effectively size equipment while supporting resilient operations of critical end-use loads.« less

Modeling Load Dynamics to Support Resiliency-based Operations in Low-Inertia Microgrids

DOE PAGES

Tuffner, Francis K.; Schneider, Kevin P.; Hansen, Jacob; ...

2018-03-07

Microgrids have repeatedly demonstrated the ability to provide uninterrupted service to critical end-use loads during normal outages, severe weather events, and natural disasters. While their ability to provide critical services is well documented, microgrids present a more dynamic operational environment than grid-connected distribution systems. The electrodynamics of a microgrid are commonly driven by the high inertia of rotating generators, which are common in many microgrids. In such high-inertia systems, the impact of end-use load electromechanical dynamics are often not examined. However, with the increased penetration of inverter-based generation with little or no inertia, it is necessary to consider the impactmore » that the dynamics of the end-use loads have on the operations of microgrids, particularly for a resiliency-based operation. These operations include, but are not limited to, switching operations, loss of generating units, and the starting of induction motors. This paper examines the importance of including multi-state electromechanical dynamic models of the end-use load when evaluating the operations of low inertia microgrids, and shows that by properly representing their behavior, it is possible to cost effectively size equipment while supporting resilient operations of critical end-use loads.« less

Improving Middle School Students’ Critical Thinking Skills Through Reading Infusion-Loaded Discovery Learning Model in the Science Instruction

NASA Astrophysics Data System (ADS)

Nuryakin; Riandi

2017-02-01

A study has been conducted to obtain a depiction of middle school students’ critical thinking skills improvement through the implementation of reading infusion-loaded discovery learning model in science instruction. A quasi-experimental study with the pretest-posttest control group design was used to engage 55 eighth-year middle school students in Tasikmalaya, which was divided into the experimental and control group respectively were 28 and 27 students. Critical thinking skills were measured using a critical thinking skills test in multiple-choice with reason format questions that administered before and after a given instruction. The test was 28 items encompassing three essential concepts, vibration, waves and auditory senses. The critical thinking skills improvement was determined by using the normalized gain score and statistically analyzed by using Mann-Whitney U test.. The findings showed that the average of students’ critical thinking skills normalized gain score of both groups were 59 and 43, respectively for experimental and control group in the medium category. There were significant differences between both group’s improvement. Thus, the implementation of reading infusion-loaded discovery learning model could further improve middle school students’ critical thinking skills than conventional learning.

The duration perception of loading applications in smartphone: Effects of different loading types.

PubMed

Zhao, Wenguo; Ge, Yan; Qu, Weina; Zhang, Kan; Sun, Xianghong

2017-11-01

The loading time of a smartphone application is an important issue, which affects the satisfaction of phone users. This study evaluated the effects of black loading screen (BLS) and animation loading screen (ALS) during application loading on users' duration perception and satisfaction. A total of 43 volunteers were enrolled. They were asked to complete several tasks by clicking the icons of each application, such as camera or message. The duration of loading time for each application was manipulated. The participants were asked to estimate the duration, evaluate the loading speed and their satisfaction. The results showed that the estimated duration increased and the satisfaction for loading period declined along with the loading time increased. Compared with the BLS, the ALS prolonged the estimated duration, and lowered the evaluation of speed and satisfaction. We also discussed the tendency and key inflection points of the curves involving the estimated duration, speed evaluation and satisfaction with the loading time. Copyright © 2017 Elsevier Ltd. All rights reserved.

Challenges in Soft Computing: Case Study with Louisville MSD CSO Modeling

NASA Astrophysics Data System (ADS)

Ormsbee, L.; Tufail, M.

2005-12-01

The principal constituents of soft computing include fuzzy logic, neural computing, evolutionary computation, machine learning, and probabilistic reasoning. There are numerous applications of these constituents (both individually and combination of two or more) in the area of water resources and environmental systems. These range from development of data driven models to optimal control strategies to assist in more informed and intelligent decision making process. Availability of data is critical to such applications and having scarce data may lead to models that do not represent the response function over the entire domain. At the same time, too much data has a tendency to lead to over-constraining of the problem. This paper will describe the application of a subset of these soft computing techniques (neural computing and genetic algorithms) to the Beargrass Creek watershed in Louisville, Kentucky. The application include development of inductive models as substitutes for more complex process-based models to predict water quality of key constituents (such as dissolved oxygen) and use them in an optimization framework for optimal load reductions. Such a process will facilitate the development of total maximum daily loads for the impaired water bodies in the watershed. Some of the challenges faced in this application include 1) uncertainty in data sets, 2) model application, and 3) development of cause-and-effect relationships between water quality constituents and watershed parameters through use of inductive models. The paper will discuss these challenges and how they affect the desired goals of the project.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Posch, M.; Kaemaeri, J.; Forsius, M.

The main objectives of this study were to identify the regions in Fennoscandia where the critical loads of sulfur (S) and acidifying nitrogen (N) for lakes are exceeded and to investigate the consequences for deposition reductions, with special emphasis on the possible trade-offs between S and N deposition in order to achieve nonexceedance. In the steady-state model for calculating critical loads and their exceedances, all relevant processes acting as sinks for N and S are considered. The critical loads of N and S are interrelated (defining the so-called critical load function), and therefore a single critical load for one pollutantmore » cannot be defined without making assumptions about the other. Comparing the present N and S deposition with the critical function for each lake allows determination of the percentage of lakes in the different regions of Fennoscandia where: (1) S reductions alone can achieve nonexceedance. (2) N reductions alone are sufficient, and (3) both N and S reductions are required but to a certain degree interchangeable. Secondly, deposition reduction requirements were assessed by fixing the N deposition to the present level, in this way analyzing the reductions required for S, and by computing the percentage of lakes exceeded in Finland, Norway and Sweden for every possible percent deposition reduction in S and N, in this way showing the (relative) effectiveness of reducing S and/or N deposition. The results showed clear regional patterns in the S and N reduction requirements. In practically the whole of Finland and the northern parts of Scandinavia man-made acidification of surface waters could be avoided by reducing S deposition alone. In the southern parts of Sweden some reductions in N deposition are clearly needed in addition to those for S. In southern Norway strong reductions are required for both N and S deposition. 55 refs., 5 figs.« less

Increasing glucose load while maintaining normoglycemia does not evoke neuronal damage in prolonged critically ill rabbits.

PubMed

Sonneville, Romain; den Hertog, Heleen M; Derde, Sarah; Güiza, Fabian; Derese, Inge; Van den Berghe, Greet; Vanhorebeek, Ilse

2013-12-01

Preventing severe hyperglycemia with insulin reduced the neuropathological alterations in frontal cortex during critical illness. We investigated the impact of increasing glucose load under normoglycemia on neurons and glial cells. Hyperinflammatory critically ill rabbits were randomized to fasting or combined parenteral nutrition containing progressively increasing amounts of glucose (low, intermediate, high) within the physiological range but with a similar amount of amino acids and lipids. In all groups, normoglycemia was maintained with insulin. On day 7, we studied the neuropathological alterations in frontal cortex neurons, astrocytes and microglia, and MnSOD as marker of oxidative stress. The percentage of damaged neurons was comparable among all critically ill and healthy rabbits. Critical illness induced an overall 1.8-fold increase in astrocyte density and activation status, largely irrespective of the nutritional intake. The percentage of microglia activation in critically ill rabbits was comparable with that in healthy rabbits, irrespective of glucose load. Likewise, MnSOD expression was comparable in critically ill and healthy rabbits without any clear impact of the nutritional interventions. During prolonged critical illness, increasing intravenous glucose infusion while strictly maintaining normoglycemia appeared safe for neuronal integrity and did not substantially affect glial cells in frontal cortex. Copyright © 2013 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism. All rights reserved.

Mechanical Behavior of Spray-Coated Metallic Laminates

NASA Astrophysics Data System (ADS)

Vackel, Andrew; Nakamura, Toshio; Sampath, Sanjay

2016-06-01

Thermal spray (TS) coatings have been extensively utilized for various surface modifications such as enhancing wear/erosion resistance and thermal protection. In the present study, a new function of TS material is explored by studying its load-carrying capability. Due to the inherent microstructures containing voids and interfaces, it has been presumed TS materials were not suitable to bear loads. However, the recent advances in TS technology to manufacture near fully dense TS coatings have expanded their potential applications. In the current experiments, TS nickel coatings are deposited onto metallic substrates, and their mechanical behaviors are closely examined. Based on the measured data, the estimated elastic modulus of TS Ni is about 130 GPa (35% less than bulk value), and the maximum tensile strength is about 500 MPa (comparable to bulk value). It was found that such a high value is attainable because the coating is deposited onto a substrate, enabling a load-transfer mechanism and preventing coating failure at a much lower stress level. Three distinct deformation stages are identified to describe this behavior. Such a clarification is critical for enabling TS process to restore structural parts as well as to additively manufacture load-bearing components.

Tribological Behavior and the Mild–Severe Wear Transition of Mg97Zn1Y2 Alloy with a LPSO Structure Phase

PubMed Central

Sun, Wei; Xuan, Xihua; Li, Liang; An, Jian

2018-01-01

Dry friction and wear tests were performed on as-cast Mg97Zn1Y2 alloy using a pin-on-disc configuration. Coefficients of friction and wear rates were measured as a function of applied load at sliding speeds of 0.2, 0.8 and 3.0 m/s. The wear mechanisms were identified in the mild and severe wear regimes by means of morphological observation and composition analysis of worn surfaces using scanning electron microscope (SEM) and energy dispersive X-ray spectrometer (EDS). Analyses of microstructure and hardness changes in subsurfaces verified the microstructure transformation from the deformed to the dynamically recrystallized, and properties changed from the strain hardening to dynamic crystallization (DRX) softening before and after the mild–severe wear transition. The mild–severe wear transition can be determined by a proposed contact surface DRX temperature criterion, from which the critical DRX temperatures at different sliding speeds are calculated using DRX dynamics; hence transition loads can also be calculated using a transition load model. The calculated transition loads are in good agreement with the measured ones, demonstrating the validity and applicability of the contact surface DRX temperature criterion. PMID:29584692

Postbuckling of magneto-electro-elastic CNT-MT composite nanotubes resting on a nonlinear elastic medium in a non-uniform thermal environment

NASA Astrophysics Data System (ADS)

Kamali, M.; Shamsi, M.; Saidi, A. R.

2018-03-01

As a first endeavor, the effect of nonlinear elastic foundation on the postbuckling behavior of smart magneto-electro-elastic (MEE) composite nanotubes is investigated. The composite nanotube is affected by a non-uniform thermal environment. A typical MEE composite nanotube consists of microtubules (MTs) and carbon nanotubes (CNTs) with a MEE cylindrical nanoshell for smart control. It is assumed that the nanoscale layers of the system are coupled by a polymer matrix or filament network depending on the application. In addition to thermal loads, magneto-electro-mechanical loads are applied to the composite nanostructure. Length scale effects are taken into account using the nonlocal elasticity theory. The principle of virtual work and von Karman's relations are used to derive the nonlinear governing differential equations of MEE CNT-MT nanotubes. Using Galerkin's method, nonlinear critical buckling loads are determined. Various types of non-uniform temperature distribution in the radial direction are considered. Finally, the effects of various parameters such as the nonlinear constant of elastic medium, thermal loading factor and small scale coefficient on the postbuckling of MEE CNT-MT nanotubes are studied.

Influence of the overall stiffness of a load-bearing porous titanium implant on bone ingrowth in critical-size mandibular bone defects in sheep.

PubMed

Schouman, T; Schmitt, M; Adam, C; Dubois, G; Rouch, P

2016-06-01

The aim of this work was to assess the influence of reduction of the apparent mechanical properties of fully load-bearing porous titanium implants used in mandibular bone defects. Segmental 18mm long bone defects were created bilaterally in the lower jaws of adult ewes. One group of 6 ewes (group A) was treated with load-bearing 'rigid' (high stiffness) porous implants on the right side, and with control on the left side. A second group of 6 ewes (group B) was treated with 'flexible' porous and control implants exhibiting apparent mechanical properties ten times lower than the rigid implants. The mechanical behavior of the reconstructed hemi-mandibles was assessed by cantilever testing and bone ingrowth into the segmental defects was assessed by BV/TV measurement within the implant using micro-CT 12 weeks after implantation. A significantly higher rigidity was identified for porous implants compared with control implants at the anterior interface in group B. BV/TV of porous implants was significantly higher than that of control implants in group A. BV/TV differences were significant between porous and control implants in group B and were homogeneous along the main axis. Significantly higher BV/TV was identified in most sub-volumes of group B porous implants compared with group A. This work highlights the critical importance of the tuning of scaffolds to promote bone ingrowth with reference to the local strains occurring within the porous scaffold, which in this application was achieved using fully load-bearing low-stiffness porous titanium implants. Copyright © 2016 Elsevier Ltd. All rights reserved.

Empirical and simulated critical loads for nitrogen deposition in California mixed conifer forests

Treesearch

M.E. Fenn; S. Jovan; F. Yuan; L. Geiser; T. Meixner; B.S. Gimeno

2008-01-01

Empirical critical loads (CL) for N deposition were determined from changes in epiphytic lichen communities, elevated NO3 leaching in streamwater, and reduced fine root biomass in ponderosa pine (Pinus ponderosa Dougl. ex Laws.) at sites with varying N deposition. The CL for lichen community impacts of 3.1 kg ha-1 year

Assessment of Nitrogen deposition effects and empirical critical loads of Nitrogen for ecoregions of the United States

Treesearch

L.H. Pardo; M.J. Robin-Abbott; C.T., eds. Driscoll

2011-01-01

This report synthesizes current research relating atmospheric nitrogen (N) deposition to effects on terrestrial and aquatic ecosystems in the United States and to identify empirical critical loads for atmospheric N deposition. The report evaluates the following receptors: freshwater diatoms, mycorrhizal fungi and other soil microbes, lichens, herbaceous plants, shrubs...

The critical loads and levels approach for nitrogen

Treesearch

T.A. Clair; T. Blett; J. Aherne; M.P.M. Aidar; R. Artz; W.J. Bealey; W. Budd; J.N. Cape; C.J. Curtis; L. Duan; M.E. Fenn; P. Groffman; R. Haeuber; J.R. Hall; J.-P. Hettelingh; D. López-Hernández; B. Mathieson; L. Pardo; M. Posch; R.V. Pouyat; T. Spranger; H. Sverdrup; H. van Dobben; A. van Hinsberg

2014-01-01

This chapter reports the findings of a Working Group to review the critical loads (CLs) and levels approach for nitrogen (N). The three main approaches to estimating CLs are empirical, mass balance and dynamic modelling. Examples are given of recent developments in Europe, North America and Asia and it is concluded that other countries should be encouraged to develop...

Effect of Substrate Bias on Friction Coefficient, Adhesion Strength and Hardness of TiN-COATED Tool Steel

NASA Astrophysics Data System (ADS)

Hamzah, Esah; Ali, Mubarak; Toff, Mohd Radzi Hj. Mohd

In the present study, TiN coatings have been deposited on D2 tool steel substrates by using cathodic arc physical vapor deposition technique. The objective of this research work is to determine the usefulness of TiN coatings in order to improve the micro-Vickers hardness and friction coefficient of TiN coating deposited on D2 tool steel, which is widely used in tooling applications. A Pin-on-Disc test was carried out to study the coefficient of friction versus sliding distance of TiN coating deposited at various substrate biases. The standard deviation parameter during tribo-test result showed that the coating deposited at substrate bias of -75 V was the most stable coating. A significant increase in micro-Vickers hardness was recorded, when substrate bias was reduced from -150 V to zero. Scratch tester was used to compare the critical loads for coatings deposited at different bias voltages and the adhesion achievable was demonstrated with relevance to the various modes, scratch macroscopic analysis, critical load, acoustic emission and penetration depth. A considerable improvement in TiN coatings was observed as a function of various substrate bias voltages.

Application of an integrated multi-criteria decision making AHP-TOPSIS methodology for ETL software selection.

PubMed

Hanine, Mohamed; Boutkhoum, Omar; Tikniouine, Abdessadek; Agouti, Tarik

2016-01-01

Actually, a set of ETL software (Extract, Transform and Load) is available to constitute a major investment market. Each ETL uses its own techniques for extracting, transforming and loading data into data warehouse, which makes the task of evaluating ETL software very difficult. However, choosing the right software of ETL is critical to the success or failure of any Business Intelligence project. As there are many impacting factors in the selection of ETL software, the same process is considered as a complex multi-criteria decision making (MCDM) problem. In this study, an application of decision-making methodology that employs the two well-known MCDM techniques, namely Analytic Hierarchy Process (AHP) and Technique for Order Preference by Similarity to Ideal Solution (TOPSIS) methods is designed. In this respect, the aim of using AHP is to analyze the structure of the ETL software selection problem and obtain weights of the selected criteria. Then, TOPSIS technique is used to calculate the alternatives' ratings. An example is given to illustrate the proposed methodology. Finally, a software prototype for demonstrating both methods is implemented.

Mesoporous biocompatible and acid-degradable magnetic colloidal nanocrystal clusters with sustainable stability and high hydrophobic drug loading capacity.

PubMed

Luo, Bin; Xu, Shuai; Luo, An; Wang, Wen-Rui; Wang, Shi-Long; Guo, Jia; Lin, Yao; Zhao, Dong-Yuan; Wang, Chang-Chun

2011-02-22

Fabrication of magnetic particles (MPs) with high magnetization and large surface area simultaneously is critical for the application of MPs in bioseparation and drug delivery but remains a challenge. In this article, we describe an unprecedented approach to synthesize mesoporous magnetic colloidal nanocrystal clusters (MCNCs) stabilized by poly(γ-glutamic acid) (PGA) with high magnetization, large surface area (136 m(2)/g) and pore volume (0.57 cm(3)/g), excellent colloidal stability, prominent biocompatibility, and acid degradability. This result provides the important step toward the construction of a new family of MCNCs and demonstrates its capacity in a "magnetic motor" drug delivery system. Here, as an example, we explore the applicability of as-prepared mesoporous MCNCs as hydrophobic drug delivery vehicles (paclitaxel as model drug), and the resultant loading capacity is as high as 35.0 wt %. The antitumor efficacy measured by MTT assay is significantly enhanced, compared with free drugs. Thus, combined with their inherent high magnetization, the mesoporous MCNCs pave the way for applying magnetic targeting drug carriers in antitumor therapeutics.

E-learning, dual-task, and cognitive load: The anatomy of a failed experiment.

PubMed

Van Nuland, Sonya E; Rogers, Kem A

2016-01-01

The rising popularity of commercial anatomy e-learning tools has been sustained, in part, due to increased annual enrollment and a reduction in laboratory hours across educational institutions. While e-learning tools continue to gain popularity, the research methodologies used to investigate their impact on learning remain imprecise. As new user interfaces are introduced, it is critical to understand how functionality can influence the load placed on a student's memory resources, also known as cognitive load. To study cognitive load, a dual-task paradigm wherein a learner performs two tasks simultaneously is often used, however, its application within educational research remains uncommon. Using previous paradigms as a guide, a dual-task methodology was developed to assess the cognitive load imposed by two commercial anatomical e-learning tools. Results indicate that the standard dual-task paradigm, as described in the literature, is insensitive to the cognitive load disparities across e-learning tool interfaces. Confounding variables included automation of responses, task performance tradeoff, and poor understanding of primary task cognitive load requirements, leading to unreliable quantitative results. By modifying the secondary task from a basic visual response to a more cognitively demanding task, such as a modified Stroop test, the automation of secondary task responses can be reduced. Furthermore, by recording baseline measures for the primary task as well as the secondary task, it is possible for task performance tradeoff to be detected. Lastly, it is imperative that the cognitive load of the primary task be designed such that it does not overwhelm the individual's ability to learn new material. © 2015 American Association of Anatomists.

14 CFR 23.775 - Windshields and windows.

Code of Federal Regulations, 2011 CFR

2011-01-01

... loadings and flight loads, or compliance with the fail-safe requirements of paragraph (d) of this section... loads combined with critical aerodynamic pressure and temperature effects, after failure of any load... in front of the pilots must be arranged so that, assuming the loss of vision through any one panel...

14 CFR 23.775 - Windshields and windows.

Code of Federal Regulations, 2010 CFR

2010-01-01

... loadings and flight loads, or compliance with the fail-safe requirements of paragraph (d) of this section... loads combined with critical aerodynamic pressure and temperature effects, after failure of any load... in front of the pilots must be arranged so that, assuming the loss of vision through any one panel...

14 CFR 23.775 - Windshields and windows.

Code of Federal Regulations, 2014 CFR

2014-01-01

... loadings and flight loads, or compliance with the fail-safe requirements of paragraph (d) of this section... loads combined with critical aerodynamic pressure and temperature effects, after failure of any load... in front of the pilots must be arranged so that, assuming the loss of vision through any one panel...

14 CFR 23.775 - Windshields and windows.

Code of Federal Regulations, 2013 CFR

2013-01-01

... loadings and flight loads, or compliance with the fail-safe requirements of paragraph (d) of this section... loads combined with critical aerodynamic pressure and temperature effects, after failure of any load... in front of the pilots must be arranged so that, assuming the loss of vision through any one panel...

14 CFR 23.775 - Windshields and windows.

Code of Federal Regulations, 2012 CFR

2012-01-01

... loadings and flight loads, or compliance with the fail-safe requirements of paragraph (d) of this section... loads combined with critical aerodynamic pressure and temperature effects, after failure of any load... in front of the pilots must be arranged so that, assuming the loss of vision through any one panel...

METHODS OF ANALYSIS FOR WASTE LOAD ALLOCATION

EPA Science Inventory

This research has addressed several unresolved questions concerning the allocation of allowable waste loads among multiple wastewater dischargers within a water quality limited stream segment. First, the traditional assumptions about critical design conditions for waste load allo...

A Critical Plane-energy Model for Multiaxial Fatigue Life Prediction of Homogeneous and Heterogeneous Materials

NASA Astrophysics Data System (ADS)

Wei, Haoyang

A new critical plane-energy model is proposed in this thesis for multiaxial fatigue life prediction of homogeneous and heterogeneous materials. Brief review of existing methods, especially on the critical plane-based and energy-based methods, are given first. Special focus is on one critical plane approach which has been shown to work for both brittle and ductile metals. The key idea is to automatically change the critical plane orientation with respect to different materials and stress states. One potential drawback of the developed model is that it needs an empirical calibration parameter for non-proportional multiaxial loadings since only the strain terms are used and the out-of-phase hardening cannot be considered. The energy-based model using the critical plane concept is proposed with help of the Mroz-Garud hardening rule to explicitly include the effect of non-proportional hardening under fatigue cyclic loadings. Thus, the empirical calibration for non-proportional loading is not needed since the out-of-phase hardening is naturally included in the stress calculation. The model predictions are compared with experimental data from open literature and it is shown the proposed model can work for both proportional and non-proportional loadings without the empirical calibration. Next, the model is extended for the fatigue analysis of heterogeneous materials integrating with finite element method. Fatigue crack initiation of representative volume of heterogeneous materials is analyzed using the developed critical plane-energy model and special focus is on the microstructure effect on the multiaxial fatigue life predictions. Several conclusions and future work is drawn based on the proposed study.

Target loads of atmospheric sulfur deposition for the protection and recovery of acid-sensitive streams in the Southern Blue Ridge Province.

PubMed

Sullivan, Timothy J; Cosby, Bernard J; Jackson, William A

2011-11-01

An important tool in the evaluation of acidification damage to aquatic and terrestrial ecosystems is the critical load (CL), which represents the steady-state level of acidic deposition below which ecological damage would not be expected to occur, according to current scientific understanding. A deposition load intended to be protective of a specified resource condition at a particular point in time is generally called a target load (TL). The CL or TL for protection of aquatic biota is generally based on maintaining surface water acid neutralizing capacity (ANC) at an acceptable level. This study included calibration and application of the watershed model MAGIC (Model of Acidification of Groundwater in Catchments) to estimate the target sulfur (S) deposition load for the protection of aquatic resources at several future points in time in 66 generally acid-sensitive watersheds in the southern Blue Ridge province of North Carolina and two adjoining states. Potential future change in nitrogen leaching is not considered. Estimated TLs for S deposition ranged from zero (ecological objective not attainable by the specified point in time) to values many times greater than current S deposition depending on the selected site, ANC endpoint, and evaluation year. For some sites, one or more of the selected target ANC critical levels (0, 20, 50, 100μeq/L) could not be achieved by the year 2100 even if S deposition was reduced to zero and maintained at that level throughout the simulation. Many of these highly sensitive streams were simulated by the model to have had preindustrial ANC below some of these target values. For other sites, the watershed soils contained sufficiently large buffering capacity that even very high sustained levels of atmospheric S deposition would not reduce stream ANC below common damage thresholds. Copyright © 2011 Elsevier Ltd. All rights reserved.

A critical role of temporoparietal junction in the integration of top-down and bottom-up attentional control

PubMed Central

Wu, Qiong; Chang, Chi-Fu; Xi, Sisi; Huang, I-Wen; Liu, Zuxiang; Juan, Chi-Hung; Wu, Yanhong; Fan, Jin

2015-01-01

Information processing can be biased toward behaviorally relevant and salient stimuli by top-down (goal-directed) and bottom-up (stimulus-driven) attentional control processes. However, the neural basis underlying the integration of these processes is not well understood. We employed functional magnetic resonance imaging and transcranial direct-current stimulation (tDCS) in humans to examine the brain mechanisms underlying the interaction between these two processes. We manipulated the cognitive load involved in top-down processing and stimulus surprise involved in bottom-up processing in a factorial design by combining a majority function task and an oddball paradigm. We found that high cognitive load and high surprise level were associated with prolonged reaction time compared to low cognitive load and low surprise level, with a synergistic interaction effect which was accompanied by a greater deactivation of bilateral temporoparietal junction (TPJ). In addition, the TPJ displayed negative functional connectivity with right middle occipital gyrus involved in bottom-up processing (modulated by the interaction effect) and the right frontal eye field (FEF) involved in top-down control. The enhanced negative functional connectivity between the TPJ and right FEF was accompanied by a larger behavioral interaction effect across subjects. Application of cathodal tDCS over the right TPJ eliminated the interaction effect. These results suggest that the TPJ plays a critical role in processing bottom-up information for top-down control of attention. PMID:26308973

P300 Event-Related Potential as an Indicator of Inattentional Deafness?

PubMed Central

Giraudet, Louise; St-Louis, Marie-Eve; Scannella, Sébastien; Causse, Mickaël

2015-01-01

An analysis of airplane accidents reveals that pilots sometimes purely fail to react to critical auditory alerts. This inability of an auditory stimulus to reach consciousness has been coined under the term of inattentional deafness. Recent data from literature tends to show that tasks involving high cognitive load consume most of the attentional capacities, leaving little or none remaining for processing any unexpected information. In addition, there is a growing body of evidence for a shared attentional capacity between vision and hearing. In this context, the abundant information in modern cockpits is likely to produce inattentional deafness. We investigated this hypothesis by combining electroencephalographic (EEG) measurements with an ecological aviation task performed under contextual variation of the cognitive load (high or low), including an alarm detection task. Two different audio tones were played: standard tones and deviant tones. Participants were instructed to ignore standard tones and to report deviant tones using a response pad. More than 31% of the deviant tones were not detected in the high load condition. Analysis of the EEG measurements showed a drastic diminution of the auditory P300 amplitude concomitant with this behavioral effect, whereas the N100 component was not affected. We suggest that these behavioral and electrophysiological results provide new insights on explaining the trend of pilots’ failure to react to critical auditory information. Relevant applications concern prevention of alarms omission, mental workload measurements and enhanced warning designs. PMID:25714746

Applications of Advanced Nondestructive Measurement Techniques to Address Safety of Flight Issues on NASA Spacecraft

NASA Technical Reports Server (NTRS)

Prosser, Bill

2016-01-01

Advanced nondestructive measurement techniques are critical for ensuring the reliability and safety of NASA spacecraft. Techniques such as infrared thermography, THz imaging, X-ray computed tomography and backscatter X-ray are used to detect indications of damage in spacecraft components and structures. Additionally, sensor and measurement systems are integrated into spacecraft to provide structural health monitoring to detect damaging events that occur during flight such as debris impacts during launch and assent or from micrometeoroid and orbital debris, or excessive loading due to anomalous flight conditions. A number of examples will be provided of how these nondestructive measurement techniques have been applied to resolve safety critical inspection concerns for the Space Shuttle, International Space Station (ISS), and a variety of launch vehicles and unmanned spacecraft.

An Ultrasonic Technique to Determine the Residual Strength of Adhesive Bonds

NASA Technical Reports Server (NTRS)

Achenbach, J. D.; Tang, Z.

1999-01-01

In this work, ultrasonic techniques to nondestructively evaluate adhesive bond degradation have been studied. The key to the present approach is the introduction of an external factor which pulls the adhesive bond in the nonlinear range, simultaneously with the application of an ultrasonic technique. With the aid of an external static tensile loading, a superimposed longitudinal wave has.been used to obtain the slopes of the stress-strain curve of an adhesive bond at a series of load levels. The critical load, at which a reduction of the slope is detected by the superimposed longitudinal wave, is an indication of the onset of nonlinear behavior of the adhesive bond, and therefore of bond degradation. This approach has been applied to the detection of adhesive bond degradation induced by cyclic fatigue loading. Analogously to the longitudinal wave case, a superimposed shear wave has been used to obtain the effective shear modulus of adhesive layers at different shear load levels. The onset of the nonlinear behavior of an adhesive bond under shear loading has been detected by the use of a superimposed shear wave. Experiments show that a longitudinal wave can also detect the nonlinear behavior when an adhesive bond is subjected to shear loading. An optimal combination of ultrasonic testing and mechanical loading methods for the detection of degradation related nonlinear behavior of adhesive bonds has been discussed. For the purpose of a practical application, an ultrasonic technique that uses a temperature increase as an alternative to static loading has also been investigated. A general strain-temperature correspondence principle that relates a mechanical strain to a temperature has been presented. Explicit strain-temperature correspondence relations for both the tension and shear cases have been derived. An important parameter which quantifies the relation between the wave velocity and temperature has been defined. This parameter, which is indicative of adhesive bond nonlinearity and which can be conveniently obtained by an ultrasonic measurement, has been used as an indication of adhesive bond degradation. Experimental results have shown that the temperature increase method is a convenient and productive alternative to static loading. A technique which uses the reflected waveform data to obtain the fundamental ultrasonic parameters (transit time, reflection coefficient and attenuation coefficient) of an adhesive bond has also been presented.

New approaches to provide ride-through for critical loads in electric power distribution systems

NASA Astrophysics Data System (ADS)

Montero-Hernandez, Oscar C.

2001-07-01

The extensive use of electronic circuits has enabled modernization, automation, miniaturization, high quality, low cost, and other achievements regarding electric loads in the last decades. However, modern electronic circuits and systems are extremely sensitive to disturbances from the electric power supply. In fact, the rate at which these disturbances happen is considerable as has been documented in recent years. In response to the power quality concerns presented previously, this dissertation is proposing new approaches to provide ride-through for critical loads during voltage disturbances with emphasis on voltage sags. In this dissertation, a new approach based on an AC-DC-AC system is proposed to provide ride-through for critical loads connected in buildings and/or an industrial system. In this approach, a three-phase IGBT inverter with a built in Dc-link voltage regulator is suitably controlled along with static by-pass switches to provide continuous power to critical loads. During a disturbance, the input utility source is disconnected and the power from the inverter is connected to the load. The remaining voltage in the AC supply is converted to DC and compensated before being applied to the inverter and the load. After detecting normal utility conditions, power from the utility is restored to the critical load. In order to achieve an extended ride-through capability a second approach is introduced. In this case, the Dc-link voltage regulator is performed by a DC-DC Buck-Boost converter. This new approach has the capability to mitigate voltage variations below and above the nominal value. In the third approach presented in this dissertation, a three-phase AC to AC boost converter is investigated. This converter provides a boosting action for the utility input voltages, right before they are applied to the load. The proposed Pulse Width Modulation (PWM) control strategy ensures independent control of each phase and compensates for both single-phase or poly-phase voltage sags. Algorithms capable of detecting voltage disturbances such as voltage sags, voltage swells, flicker, frequency change, and harmonics in a fast and reliable way are investigated and developed in this dissertation as an essential part of the approaches previously described. Simulation and experimental work has been done to validate the feasibility of all approaches under the most common voltage disturbances such as single-phase voltage sags and three-phase voltage sags.

DOE Office of Scientific and Technical Information (OSTI.GOV)

McCaskey, Alexander J.

Hybrid programming models for beyond-CMOS technologies will prove critical for integrating new computing technologies alongside our existing infrastructure. Unfortunately the software infrastructure required to enable this is lacking or not available. XACC is a programming framework for extreme-scale, post-exascale accelerator architectures that integrates alongside existing conventional applications. It is a pluggable framework for programming languages developed for next-gen computing hardware architectures like quantum and neuromorphic computing. It lets computational scientists efficiently off-load classically intractable work to attached accelerators through user-friendly Kernel definitions. XACC makes post-exascale hybrid programming approachable for domain computational scientists.

Subtleties in practical application of prolonged infusion of β-lactam antibiotics.

PubMed

De Waele, Jan J; Lipman, Jeffrey; Carlier, Mieke; Roberts, Jason A

2015-05-01

Prolonged infusion (PI) of β-lactam antibiotics is increasingly used in order to optimise antibiotic exposure in critically ill patients. Physicians are often not aware of a number of subtleties that may jeopardise the treatment. In this clinically based paper, we stress pragmatic issues, such as the importance of a loading dose before PI, and discuss a number of important practicalities that are mandatory to benefit from the pharmacokinetic advantages of prolonged β-lactam antibiotic administration. Copyright © 2015 Elsevier B.V. and the International Society of Chemotherapy. All rights reserved.

Stress-Displacement Relations and Terrain-Vehicle Mechanics: A Critical Discussion

DTIC Science & Technology

1968-12-01

a definitl.! coherent r nttcrn of rupture surfaces if the geometrica l and load conditions are n t a !ta cG !1y .he flow process itself. The...4 (as shown for one example at <he bo tom of the fiaurc). After application of the appropriate correction factor to account for the diftcrent tan...Sela’s theory is correct . Jtouahly 50 per r.ent of the experimental M I RW curves arc beyond these limits, wlllcla IIIIDituiBcieat to reject SoJa’s

Application of Advanced Nondestructive Evaluation Techniques for Cylindrical Composite Test Samples

NASA Technical Reports Server (NTRS)

Martin, Richard E.; Roth, Donald J.; Salem, Jonathan A.

2013-01-01

Two nondestructive methods were applied to composite cylinder samples pressurized to failure in order to determine manufacturing quality and monitor damage progression under load. A unique computed tomography (CT) image processing methodology developed at NASA Glenn Research was used to assess the condition of the as-received samples while acoustic emission (AE) monitoring was used to identify both the extent and location of damage within the samples up to failure. Results show the effectiveness of both of these methods in identifying potentially critical fabrication issues and their resulting impact on performance.

Designing a Dynamic Data Driven Application System for Estimating Real-Time Load of DOC in a River

NASA Astrophysics Data System (ADS)

Ouyang, Y.; None

2011-12-01

Understanding the dynamics of naturally occurring dissolved organic carbon (DOC) in a river is central to estimating surface water quality, aquatic carbon cycling, and climate change. Currently, determination of DOC in surface water is primarily accomplished by manually collecting samples for laboratory analysis, which requires at least 24 hours. In other words, no effort has been devoted to monitoring real-time variations of DOC in a river due to the lack of suitable and/or cost-effective wireless sensors. However, when considering human health, carbon footprints, and effects of urbanization, industry, and agriculture on water resource supply, timely DOC information may be critical. We have developed here a new paradigm, a dynamic data driven application system (DDDAS), for estimating the real-time load of DOC into a river. This DDDAS consisted of the following four components: (1) a Visual Basic (VB) program for downloading US Geological Survey real-time chlorophyll and discharge data; (2) a STELLA model for evaluating real-time DOC load based on the relationship between chlorophyll a, DOC, and river discharge; (3) a batch file for linking the VB program and STELLA model; and (4) a Microsoft Windows Scheduled Tasks wizard for executing the model and displaying output on a computer screen at selected times. Results show that the real-time load of DOC into the St. Johns River basin near Satsuma, Putnam County, Florida, USA varied over a range from -13,143 to 29,248 kg/h at the selected site in Florida, USA. The negative loads occurred because of the back flow in the estuarine reach of the river. The cumulative load of DOC in the river for the selected site at the end of the simulation (178 hours) was about 1.2 tons. Our results support the utility of the DDDAS developed in this study for estimating the real-time variations of DOC in river ecosystems.

LBMR: Load-Balanced Multipath Routing for Wireless Data-Intensive Transmission in Real-Time Medical Monitoring.

PubMed

Tseng, Chinyang Henry

2016-05-31

In wireless networks, low-power Zigbee is an excellent network solution for wireless medical monitoring systems. Medical monitoring generally involves transmission of a large amount of data and easily causes bottleneck problems. Although Zigbee's AODV mesh routing provides extensible multi-hop data transmission to extend network coverage, it originally does not, and needs to support some form of load balancing mechanism to avoid bottlenecks. To guarantee a more reliable multi-hop data transmission for life-critical medical applications, we have developed a multipath solution, called Load-Balanced Multipath Routing (LBMR) to replace Zigbee's routing mechanism. LBMR consists of three main parts: Layer Routing Construction (LRC), a Load Estimation Algorithm (LEA), and a Route Maintenance (RM) mechanism. LRC assigns nodes into different layers based on the node's distance to the medical data gateway. Nodes can have multiple next-hops delivering medical data toward the gateway. All neighboring layer-nodes exchange flow information containing current load, which is the used by the LEA to estimate future load of next-hops to the gateway. With LBMR, nodes can choose the neighbors with the least load as the next-hops and thus can achieve load balancing and avoid bottlenecks. Furthermore, RM can detect route failures in real-time and perform route redirection to ensure routing robustness. Since LRC and LEA prevent bottlenecks while RM ensures routing fault tolerance, LBMR provides a highly reliable routing service for medical monitoring. To evaluate these accomplishments, we compare LBMR with Zigbee's AODV and another multipath protocol, AOMDV. The simulation results demonstrate LBMR achieves better load balancing, less unreachable nodes, and better packet delivery ratio than either AODV or AOMDV.

LBMR: Load-Balanced Multipath Routing for Wireless Data-Intensive Transmission in Real-Time Medical Monitoring

PubMed Central

Tseng, Chinyang Henry

2016-01-01

In wireless networks, low-power Zigbee is an excellent network solution for wireless medical monitoring systems. Medical monitoring generally involves transmission of a large amount of data and easily causes bottleneck problems. Although Zigbee’s AODV mesh routing provides extensible multi-hop data transmission to extend network coverage, it originally does not, and needs to support some form of load balancing mechanism to avoid bottlenecks. To guarantee a more reliable multi-hop data transmission for life-critical medical applications, we have developed a multipath solution, called Load-Balanced Multipath Routing (LBMR) to replace Zigbee’s routing mechanism. LBMR consists of three main parts: Layer Routing Construction (LRC), a Load Estimation Algorithm (LEA), and a Route Maintenance (RM) mechanism. LRC assigns nodes into different layers based on the node’s distance to the medical data gateway. Nodes can have multiple next-hops delivering medical data toward the gateway. All neighboring layer-nodes exchange flow information containing current load, which is the used by the LEA to estimate future load of next-hops to the gateway. With LBMR, nodes can choose the neighbors with the least load as the next-hops and thus can achieve load balancing and avoid bottlenecks. Furthermore, RM can detect route failures in real-time and perform route redirection to ensure routing robustness. Since LRC and LEA prevent bottlenecks while RM ensures routing fault tolerance, LBMR provides a highly reliable routing service for medical monitoring. To evaluate these accomplishments, we compare LBMR with Zigbee’s AODV and another multipath protocol, AOMDV. The simulation results demonstrate LBMR achieves better load balancing, less unreachable nodes, and better packet delivery ratio than either AODV or AOMDV. PMID:27258297

A comparison of empirical and modeled nitrogen critical loads for Mediterranean forests and shrublands in California

Treesearch

M.E. Fenn; H.-D. Nagel; I. Koseva; J. Aherne; S.E. Jovan; L.H. Geiser; A. Schlutow; T. Scheuschner; A. Bytnerowicz; B.S. Gimeno; F. Yuan; S.A. Watmough; E.B. Allen; R.F. Johnson; T. Meixner

2014-01-01

Nitrogen (N) deposition is impacting a number of ecosystem types in California. Critical loads (CLs) for N deposition determined for mixed conifer forests and chaparral/oak woodlands in the Sierra Nevada Mountains of California and the San Bernardino Mountains in southern California using empirical and various modelling approaches were compared. Models used included...

Using fire risk and species loss to set critical loads for nitrogen deposition in southern California shrublands

Treesearch

E.B. Allen; L.E. Rao; G. Tonnesen; R.F. Johnson; M.E. Fenn; A. Bytnerowicz

2014-01-01

Southern California deserts and coastal sage scrub (CSS) are undergoing vegetation-type conversion to exotic annual grassland, especially in regions downwind of urban areas that receive high nitrogen (N), primarily as dry deposition. To determine critical loads (CLs) of N that cause negative impacts, we measured plant and soil responses along N deposition gradients,...

Cognitive Load Criteria for Critical Evaluation and Selection of Web-Based Resources for Science Teaching.

ERIC Educational Resources Information Center

Klemm, E. Barbara; Iding, Marie K.; Crosby, Martha E.

This study addresses the need to develop research-based criteria for science teacher educators to use in preparing teachers to critically evaluate and select web-based resources for their students' use. The study focuses on the cognitive load imposed on the learner for tasks required in using text, illustrations, and other features of multi-…

Developing Critical Loads of acidity for streams in the Great Smoky Mountains National Park, using PnET-BGC model

NASA Astrophysics Data System (ADS)

Fakhraei, H.

2015-12-01

Acid deposition has impaired acid-sensitive streams and reduced aquatic biotic integrity in Great Smoky Mountains National Park (GRSM) by decreasing pH and acid neutralizing capacity (ANC). Twelve streams in GRSM are listed by the state of Tennessee as impaired due to low stream pH (pH<6.0) under Section 303(d) of the Clean Water Act. A dynamic biogeochemical model, PnET-BGC, was used to evaluate past, current and potential future changes in soil and water chemistry of watersheds of GRSM in response to changes in acid deposition. Calibrating 30 stream-watersheds in GRSM (including 12 listed impaired streams) to the long-term stream chemistry observations, the model was parameterized for the Park. The calibrated model was used to evaluate the level of atmospheric deposition above which harmful effects occur, known as "critical loads", for individual study watersheds. Estimated critical loads and exceedances (levels of deposition above the critical load) of atmospheric sulfur and nitrogen deposition were depicted through geographic information system maps. Accuracy of model simulations in the presence of uncertainties in the estimated model parameters and inputs was assessed using three uncertainty and sensitivity techniques.

Impact of nitrogen deposition at the species level.

PubMed

Payne, Richard J; Dise, Nancy B; Stevens, Carly J; Gowing, David J

2013-01-15

In Europe and, increasingly, the rest of the world, the key policy tool for the control of air pollution is the critical load, a level of pollution below which there are no known significant harmful effects on the environment. Critical loads are used to map sensitive regions and habitats, permit individual polluting activities, and frame international negotiations on transboundary air pollution. Despite their fundamental importance in environmental science and policy, there has been no systematic attempt to verify a critical load with field survey data. Here, we use a large dataset of European grasslands along a gradient of nitrogen (N) deposition to show statistically significant declines in the abundance of species from the lowest level of N deposition at which it is possible to identify a change. Approximately 60% of species change points occur at or below the range of the currently established critical load. If this result is found more widely, the underlying principle of no harm in pollution policy may need to be modified to one of informed decisions on how much harm is acceptable. Our results highlight the importance of protecting currently unpolluted areas from new pollution sources, because we cannot rule out ecological impacts from even relatively small increases in reactive N deposition.

Simulation of Human-induced Vibrations Based on the Characterized In-field Pedestrian Behavior

PubMed Central

Van Nimmen, Katrien; Lombaert, Geert; De Roeck, Guido; Van den Broeck, Peter

2016-01-01

For slender and lightweight structures, vibration serviceability is a matter of growing concern, often constituting the critical design requirement. With designs governed by the dynamic performance under human-induced loads, a strong demand exists for the verification and refinement of currently available load models. The present contribution uses a 3D inertial motion tracking technique for the characterization of the in-field pedestrian behavior. The technique is first tested in laboratory experiments with simultaneous registration of the corresponding ground reaction forces. The experiments include walking persons as well as rhythmical human activities such as jumping and bobbing. It is shown that the registered motion allows for the identification of the time variant pacing rate of the activity. Together with the weight of the person and the application of generalized force models available in literature, the identified time-variant pacing rate allows to characterize the human-induced loads. In addition, time synchronization among the wireless motion trackers allows identifying the synchronization rate among the participants. Subsequently, the technique is used on a real footbridge where both the motion of the persons and the induced structural vibrations are registered. It is shown how the characterized in-field pedestrian behavior can be applied to simulate the induced structural response. It is demonstrated that the in situ identified pacing rate and synchronization rate constitute an essential input for the simulation and verification of the human-induced loads. The main potential applications of the proposed methodology are the estimation of human-structure interaction phenomena and the development of suitable models for the correlation among pedestrians in real traffic conditions. PMID:27167309

Dynamic load balancing of applications

DOEpatents

Wheat, Stephen R.

1997-01-01

An application-level method for dynamically maintaining global load balance on a parallel computer, particularly on massively parallel MIMD computers. Global load balancing is achieved by overlapping neighborhoods of processors, where each neighborhood performs local load balancing. The method supports a large class of finite element and finite difference based applications and provides an automatic element management system to which applications are easily integrated.

Fracture analysis of stiffened panels under biaxial loading with widespread cracking

NASA Technical Reports Server (NTRS)

Newman, J. C., Jr.; Dawicke, D. S.

1995-01-01

An elastic-plastic finite-element analysis with a critical crack-tip-opening angle (CTOA) fracture criterion was used to model stable crack growth and fracture of 2024-T3 aluminum alloy (bare and clad) panels for several thicknesses. The panels had either single or multiple-site damage (MSD) cracks subjected to uniaxial or biaxial loading. Analyses were also conducted on cracked stiffened panels with single or MSD cracks. The critical CTOA value for each thickness was determined by matching the failure load on a middle-crack tension specimen. Comparisons were made between the critical angles determined from the finite-element analyses and those measured with photographic methods. Predicted load-against-crack extension and failure loads for panels under biaxial loading, panels with MSD cracks, and panels with various number of stiffeners were compared with test data, whenever possible. The predicted results agreed well with the test data even for large-scale plastic deformations. The analyses were also able to predict stable tearing behavior of a large lead crack in the presence of MSD cracks. The analyses were then used to study the influence of stiffeners on residual strength in the presence of widespread fatigue cracking. Small MSD cracks were found to greatly reduce the residual strength for large lead cracks even for stiffened panels.

Critical current degradation behaviour of GdBCO CC tapes in pure torsion and combined tension-torsion modes

NASA Astrophysics Data System (ADS)

Gorospe, Alking; Bautista, Zhierwinjay; Shin, Hyung-Seop

2016-10-01

Coated conductor (CC) tapes utilized in high-current-density superconducting cables are commonly subjected to different loading modes, primarily torsion and tension especially in the case of twisted stacked-tape cable. Torsion load can occur due to twisting along the length or when winding the CC tapes around a former, while tension load can occur due to pre-tension when coiled and as a hoop stress when the coil is energized. In this study, electromechanical properties of single CC tapes under torsion load were investigated using a new test apparatus. The results could provide basic information for cable designers to fully characterize stacked cables. Copper-electroplated and brass-laminated CC tapes fabricated with different deposition techniques were subjected to pure torsion and combined tension-torsion loading. The critical current, I c degradation behaviours of CC tapes under torsional deformation were examined. Also, the effect of further external lamination on the I c degradation behaviour of the CC tapes under such loading conditions was investigated. In the case of the combined tension-torsion test, short samples were subjected to twist pitches of 200 mm and 100 mm. Critical parameters including reversible axial stress and strain in such twist pitch conditions were also investigated.

Fracture analysis of stiffened panels under biaxial loading with widespread cracking

NASA Technical Reports Server (NTRS)

Newman, J. C., Jr.

1995-01-01

An elastic-plastic finite-element analysis with a critical crack-tip opening angle (CTOA) fracture criterion was used to model stable crack growth and fracture of 2024-T3 aluminum alloy (bare and clad) panels for several thicknesses. The panels had either single or multiple-site damage (MSD) cracks subjected to uniaxial or biaxial loading. Analyses were also conducted on cracked stiffened panels with single or MSD cracks. The critical CTOA value for each thickness was determined by matching the failure load on a middle-crack tension specimen. Comparisons were made between the critical angles determined from the finite-element analyses and those measured with photographic methods. Predicted load-against-crack extension and failure loads for panels under biaxial loading, panels with MSD cracks, and panels with various numbers of stiffeners were compared with test data whenever possible. The predicted results agreed well with the test data even for large-scale plastic deformations. The analyses were also able to predict stable tearing behavior of a large lead crack in the presence of MSD cracks. The analyses were then used to study the influence of stiffeners on residual strength in the presence of widespread fatigue cracking. Small MSD cracks were found to greatly reduce the residual strength for large lead cracks even for stiffened panels.

Experimental verification of Advanced Collapsed-cone Engine for use with a multichannel vaginal cylinder applicator.

PubMed

Cawston-Grant, Brie; Morrison, Hali; Menon, Geetha; Sloboda, Ron S

2017-05-01

Model-based dose calculation algorithms have recently been incorporated into brachytherapy treatment planning systems, and their introduction requires critical evaluation before clinical implementation. Here, we present an experimental evaluation of Oncentra ® Brachy Advanced Collapsed-cone Engine (ACE) for a multichannel vaginal cylinder (MCVC) applicator using radiochromic film. A uniform dose of 500 cGy was specified to the surface of the MCVC using the TG-43 dose formalism under two conditions: (a) with only the central channel loaded or (b) only the peripheral channels loaded. Film measurements were made at the applicator surface and compared to the doses calculated using TG-43, standard accuracy ACE (sACE), and high accuracy ACE (hACE). When the central channel of the applicator was used, the film measurements showed a dose increase of (11 ± 8)% (k = 2) above the two outer grooves on the applicator surface. This increase in dose was confirmed with the hACE calculations, but was not confirmed with the sACE calculations at the applicator surface. When the peripheral channels were used, a periodic azimuthal variation in measured dose was observed around the applicator. The sACE and hACE calculations confirmed this variation and agreed within 1% of each other at the applicator surface. Additionally for the film measurements with the central channel used, a baseline dose variation of (10 ± 4)% (k = 2) of the mean dose was observed azimuthally around the applicator surface, which can be explained by offset source positioning in the central channel. © 2017 The Authors. Journal of Applied Clinical Medical Physics published by Wiley Periodicals, Inc. on behalf of American Association of Physicists in Medicine.

Glass breaking strength: The role of surface flaws and treatments

NASA Technical Reports Server (NTRS)

Moore, D.

1985-01-01

Although the intrinsic strength of silicon dioxide glass is of the order of 10 to the 6th power lb/sq in, the practical strength is roughly two orders of magnitude below this theoretical limit, and depends almost entirely on the surface condition of the glass, that is, the number and size of flaws and the residual surface compression (temper) in the glass. Glass parts always fail in tension when these flaws grow under sustained loading to some critical size. Research associated with glass encapsulated crystalline-Si photovoltaic (PV) modules has greatly expanded our knowledge of glass breaking strength and developed sizeable data base for commercially available glass types. A detailed design algorithm is developed for thickness sizing of rectangular glass plates subject to pressure loads. Additional studies examine the strength of glass under impact loading conditions such as that caused by hail. Although the fundamentals of glass breakage are directly applicable to thin film modules, the fracture strength of typical numerical glass must be replaced with data that reflect the high temperature tin oxide processing, laser scribing, and edge processing peculiar to thin film modules. The fundamentals of glass breakage applicable to thin film modules and preliminary fracture strength data for a variety of 1 ft square glass specimens representing preprocessed and post processed sheets from current amorphous-Si module manufacturers are presented.

Control Design Strategies to Enhance Long-Term Aircraft Structural Integrity

NASA Technical Reports Server (NTRS)

Newman, Brett A.

1999-01-01

Over the operational lifetime of both military and civil aircraft, structural components are exposed to hundreds of thousands of low-stress repetitive load cycles and less frequent but higher-stress transient loads originating from maneuvering flight and atmospheric gusts. Micro-material imperfections in the structure, such as cracks and debonded laminates, expand and grow in this environment, reducing the structural integrity and shortening the life of the airframe. Extreme costs associated with refurbishment of critical load-bearing structural components in a large fleet, or altogether reinventoring the fleet with newer models, indicate alternative solutions for life extension of the airframe structure are highly desirable. Increased levels of operational safety and reliability are also important factors influencing the desirability of such solutions. One area having significant potential for impacting crack growth/fatigue damage reduction and structural life extension is flight control. To modify the airframe response dynamics arising from command inputs and gust disturbances, feedback loops are routinely applied to vehicles. A dexterous flight control system architecture senses key vehicle motions and generates critical forces/moments at multiple points distributed throughout the airframe to elicit the desired motion characteristics. In principle, these same control loops can be utilized to influence the level of exposure to harmful loads during flight on structural components. Project objectives are to investigate and/or assess the leverage control has on reducing fatigue damage and enhancing long-term structural integrity, without degrading attitude control and trajectory guidance performance levels. In particular, efforts have focused on the effects inner loop control parameters and architectures have on fatigue damage rate. To complete this research, an actively controlled flexible aircraft model and a new state space modeling procedure for crack growth have been utilized. Analysis of the analytical state space model for crack growth revealed the critical mathematical factors, and hence the physical mechanism they represent, that influenced high rates of airframe crack growth. The crack model was then exercised with simple load inputs to uncover and expose key crack growth behavior. To characterize crack growth behavior, both "short-term" laboratory specimen test type inputs and "long-term" operational flight type inputs were considered. Harmonic loading with a single overload revealed typical exponential crack growth behavior until the overload application, after which time the crack growth was retarded for a period of time depending on the overload strength. An optimum overload strength was identified which leads to maximum retardation of crack growth. Harmonic loading with a repeated overload of varying strength and frequency again revealed an optimum overload trait for maximizing growth retardation. The optimum overload strength ratio lies near the range of 2 to 3 with dependency on frequency. Experimental data was found to correlate well with the analytical predictions.

Ranges of applicability for the continuum beam model in the mechanics of carbon nanotubes and nanorods

NASA Technical Reports Server (NTRS)

Harik, V. M.

2001-01-01

Limitations in the validity of the continuum beam model for carbon nanotubes (NTs) and nanorods are examined. Applicability of all assumptions used in the model is restricted by the two criteria for geometric parameters that characterize the structure of NTs. The key non-dimensional parameters that control the NT buckling behavior are derived via dimensional analysis of the nanomechanical problem. A mechanical law of geometric similitude for NT buckling is extended from continuum mechanics for different molecular structures. A model applicability map, where two classes of beam-like NTs are identified, is constructed for distinct ranges of non-dimensional parameters. Expressions for the critical buckling loads and strains are tailored for two classes of NTs and compared with the data provided by the molecular dynamics simulations. copyright 2001 Elsevier Science Ltd. All rights reserved.

An Analysis of Performance Enhancement Techniques for Overset Grid Applications

NASA Technical Reports Server (NTRS)

Djomehri, J. J.; Biswas, R.; Potsdam, M.; Strawn, R. C.; Biegel, Bryan (Technical Monitor)

2002-01-01

The overset grid methodology has significantly reduced time-to-solution of high-fidelity computational fluid dynamics (CFD) simulations about complex aerospace configurations. The solution process resolves the geometrical complexity of the problem domain by using separately generated but overlapping structured discretization grids that periodically exchange information through interpolation. However, high performance computations of such large-scale realistic applications must be handled efficiently on state-of-the-art parallel supercomputers. This paper analyzes the effects of various performance enhancement techniques on the parallel efficiency of an overset grid Navier-Stokes CFD application running on an SGI Origin2000 machine. Specifically, the role of asynchronous communication, grid splitting, and grid grouping strategies are presented and discussed. Results indicate that performance depends critically on the level of latency hiding and the quality of load balancing across the processors.

Modelling and mapping long-term risks due to reactive nitrogen effects: an overview of LRTAP convention activities.

PubMed

Spranger, T; Hettelingh, J-P; Slootweg, J; Posch, M

2008-08-01

Long-range transboundary air pollution has caused severe environmental effects in Europe. European air pollution abatement policy, in the framework of the UNECE Convention on Long-range Transboundary Air Pollution (LRTAP Convention) and the European Union Clean Air for Europe (CAFE) programme, has used critical loads and their exceedances by atmospheric deposition to design emission abatement targets and strategies. The LRTAP Convention International Cooperative Programme on Modelling and Mapping Critical Loads and Levels and Air Pollution Effects, Risks and Trends (ICP M&M) generates European critical loads datasets to enable this work. Developing dynamic nitrogen flux models and using them for a prognosis and assessment of nitrogen effects remains a challenge. Further research is needed on links between nitrogen deposition effects, climate change, and biodiversity.

Lateral-Torsional Buckling Instability Caused by Individuals Walking on Wood Composite I-Joists

NASA Astrophysics Data System (ADS)

Villasenor Aguilar, Jose Maria

Recent research has shown that a significant number of the falls from elevation occur when laborers are working on unfinished structures. Workers walking on wood I-joists on roofs and floors are prone to fall hazards. Wood I-joists have been replacing dimension lumber for many floor systems and a substantial number of roof systems in light-frame construction. Wood I-joists are designed to resist axial stresses on the flanges and shear stresses on the web while minimizing material used. However, wood I-joists have poor resistance to applied lateral and torsional loads and are susceptible to lateral-torsional buckling instability. Workers walking on unbraced or partially braced wood I-joists can induce axial and lateral forces as well as twist. Experimental testing demonstrated that workers cause lateral-torsional buckling instability in wood I-joists. However, no research was found related to the lateral-torsional buckling instability induced by individuals walking on the wood I-joists. Furthermore, no research was found considering the effects of the supported end conditions and partial bracing in the lateral-torsional buckling instability of wood I-joists. The goal of this research was to derive mathematical models to predict the dynamic lateral-torsional buckling instability of wood composite I-joists loaded by individuals walking considering different supported end conditions and bracing system configurations. The dynamic lateral-torsional buckling instability was analyzed by linearly combining the static lateral-torsional buckling instability with the lateral bending motion of the wood Ijoists. Mathematical models were derived to calculate the static critical loads for the simply supported end condition and four wood I-joist hanger supported end conditions. Additionally, mathematical models were derived to calculate the dynamic maximum lateral displacements and positions of the individual walking on the wood Ijoists for the same five different supported end conditions. Three different lean-on bracing systems were investigated, non-bracing, one-bracing, and two-bracing systems. Mathematical models were derived to calculate the amount of constraint due to the lean-on bracing system. The derived mathematical models were validated by comparison to data from testing for all supported end conditions and bracing systems. The predicted critical loads using the static buckling theoretical models for the non-bracing system and the static buckling theoretical models combined with the bracing theoretical models for the simply and hanger supported end conditions agreed well with the critical loads obtained from testing for the two wood I-joist sizes investigated. The predicted maximum lateral displacements and individual positions using the bending motion theoretical models for the simply and hanger supported end conditions agreed well with the corresponding maximum lateral displacements and individual positions obtained from testing for both wood I-joist sizes. Results showed that; a) the supported end condition influenced the critical loads, maximum lateral displacements and individual positions, b) the bracing system increased the critical loads and reduced the maximum lateral displacements, c) the critical load increased as the load position displaced away from the wood I-joist mid-span, d) the critical load reduced as the initial lateral displacement of the wood I-joist increased and e) the wood I-joist mid-span was the critical point in the dynamic lateral-torsional buckling instability.

Accommodating oversize and overweight loads : technical report.

DOT National Transportation Integrated Search

2012-07-01

Adequate management of oversize/overweight (OS/OW) permit loads throughout the state of Texas is : critical to maintaining a vibrant state economy. The growth in the number and size of permit loads in recent : years is clear evidence that new tools a...

Prediction of shear critical behavior of high-strength reinforced concrete columns using finite element methods

NASA Astrophysics Data System (ADS)

Alrasyid, Harun; Safi, Fahrudin; Iranata, Data; Chen-Ou, Yu

2017-11-01

This research shows the prediction of shear behavior of High-Strength Reinforced Concrete Columns using Finite-Element Method. The experimental data of nine half scale high-strength reinforced concrete were selected. These columns using specified concrete compressive strength of 70 MPa, specified yield strength of longitudinal and transverse reinforcement of 685 and 785 MPa, respectively. The VecTor2 finite element software was used to simulate the shear critical behavior of these columns. The combination axial compression load and monotonic loading were applied at this prediction. It is demonstrated that VecTor2 finite element software provides accurate prediction of load-deflection up to peak at applied load, but provide similar behavior at post peak load. The shear strength prediction provide by VecTor 2 are slightly conservative compare to test result.

Parallelizing serial code for a distributed processing environment with an application to high frequency electromagnetic scattering

NASA Astrophysics Data System (ADS)

Work, Paul R.

1991-12-01

This thesis investigates the parallelization of existing serial programs in computational electromagnetics for use in a parallel environment. Existing algorithms for calculating the radar cross section of an object are covered, and a ray-tracing code is chosen for implementation on a parallel machine. Current parallel architectures are introduced and a suitable parallel machine is selected for the implementation of the chosen ray-tracing algorithm. The standard techniques for the parallelization of serial codes are discussed, including load balancing and decomposition considerations, and appropriate methods for the parallelization effort are selected. A load balancing algorithm is modified to increase the efficiency of the application, and a high level design of the structure of the serial program is presented. A detailed design of the modifications for the parallel implementation is also included, with both the high level and the detailed design specified in a high level design language called UNITY. The correctness of the design is proven using UNITY and standard logic operations. The theoretical and empirical results show that it is possible to achieve an efficient parallel application for a serial computational electromagnetic program where the characteristics of the algorithm and the target architecture critically influence the development of such an implementation.

A study of mechanical properties for aluminum GMA weldments

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kluken, A.O.; Bjoerneklett, B.

1997-02-01

Medium- to high-strength aluminum alloys represent an attractive alternative to steel as a material for critical structural members. One area of great interest for their use is the transportation industry due to the increasing demands for less environmental impact through improved fuel efficiency, weight reductions, and increased load capacity. Fabrication of structural bodies involves, in most instances, the application of a joining process. Load-carrying members must be joined together or nonload-carrying parts attached to the primary structure. Although adhesive bonding, laser beam welding and friction stir welding are attractive processes for joining of aluminum, gas metal arc welding (GMAW) ismore » by far the most widely used process at present. Fusion welding of a heat-treatable aluminum alloy represents an additional local heat treatment of material that previously has been processed through tight temperature control to obtain the desired mechanical properties. Hence, great attention must be given to selection of alloy and temper condition, welding parameters, and postweld aging procedures for a given application. The objective of this investigation was to establish mechanical property data, i.e., tensile strength and impact toughness, for Al-Mg-Si and Al-Zn-Mg gas metal arc weldments applicable to the automotive and shipbuilding industries.« less

Optimizing thickness of ceramic coatings on plastic components for orthopedic applications: A finite element analysis.

PubMed

Marchiori, G; Lopomo, N; Boi, M; Berni, M; Bianchi, M; Gambardella, A; Visani, A; Russo, A; Marcacci, M

2016-01-01

Realizing hard ceramic coatings on the plastic component of a joint prosthesis can be strategic for the mechanical preservation of the whole implant and to extend its lifetime. Recently, thanks to the Plasma Pulsed Deposition (PPD) method, zirconia coatings on ultra-high molecular weight polyethylene (UHMWPE) substrates resulted in a feasible outcome. Focusing on both the highly specific requirements defined by the biomedical application and the effective possibilities given by the deposition method in the perspectives of technological transfer, it is mandatory to optimize the coating in terms of load bearing capacity. The main goal of this study was to identify through Finite Element Analysis (FEA) the optimal coating thickness that would be able to minimize UHMWPE strain, possible insurgence of cracks within the coating and stresses at coating-substrate interface. Simulations of nanoindentation and microindentation tests were specifically carried out. FEA findings demonstrated that, in general, thickening the zirconia coating strongly reduced the strains in the UHMWPE substrate, although the 1 μm thickness value was identified as critical for the presence of high stresses within the coating and at the interface with the substrate. Therefore, the optimal thickness resulted to be highly dependent on the specific loading condition and final applications. Copyright © 2015 Elsevier B.V. All rights reserved.

Stepwise morphological evolution of the active Yellow River (Huanghe) delta lobe (1976-2013): Dominant roles of riverine discharge and sediment grain size

NASA Astrophysics Data System (ADS)

Wu, Xiao; Bi, Naishuang; Xu, Jingping; Nittrouer, Jeffrey A.; Yang, Zuosheng; Saito, Yoshiki; Wang, Houjie

2017-09-01

The presently active Yellow River (Huanghe) delta lobe has been formed since 1976 when the river was artificially diverted. The process and driving forces of morphological evolution of the present delta lobe still remain unclear. Here we examined the stepwise morphological evolution of the active Yellow River delta lobe including both the subaerial and the subaqueous components, and illustrated the critical roles of riverine discharge and sediment grain size in dominating the deltaic evolution. The critical sediment loads for maintaining the delta stability were also calculated from water discharge and sediment load measured at station Lijin, the last gauging station approximately 100 km upstream from the river mouth. The results indicated that the development of active delta lobe including both subaerial and subaqueous components has experienced four sequential stages. During the first stage (1976-1981) after the channel migration, the unchannelized river flow enhanced deposition within the channel and floodplain between Lijin station and the river mouth. Therefore, the critical sediment supply calculated by the river inputs obtained from station Lijin was the highest. However, the actual sediment load at this stage (0.84 Gt/yr) was more than twice of the critical sediment load ( 0.35 Gt/yr) for sustaining the active subaerial area, which favored a rapid seaward progradation of the Yellow River subaerial delta. During the second stage (1981-1996), the engineering-facilitated channelized river flow and the increase in median grain size of suspended sediment delivered to the sea resulted in the critical sediment load for keeping the delta stability deceasing to 0.29 Gt/yr. The active delta lobe still gradually prograded seaward at an accretion rate of 11.9 km2/yr at this stage as the annual sediment load at Lijin station was 0.55 Gt/yr. From 1996 to 2002, the critical sediment load further decreased to 0.15 Gt/yr with the sediment grain size increased to 22.5 μm; however, the delta suffered net erosion because of the insufficient sediment supply (0.11 Gt/yr). In the most recent stage (2002 - 2013), the intensive scouring of the lower river channel induced by the dam regulation provided relatively coarser sediment, which effectively reduced the critical sediment load to 0.06 Gt/yr, much lower than the corresponding sediment load at Lijin station ( 0.16 Gt/yr). Consequently, the subaerial Yellow River delta transitioned to a slight accretion phase. Overall, the evolution of the active Yellow River delta is highly correlated to riverine water and sediment discharge. The sediment supply for keeping the subaerial delta stability is inconstant and varying with the river channel morphology and sediment grain size. We conclude that the human-impacted riverine sediment discharge and grain-size composition play dominant roles in the stepwise morphological evolution of the active delta lobe.

Dynamic load balancing of applications

DOEpatents

Wheat, S.R.

1997-05-13

An application-level method for dynamically maintaining global load balance on a parallel computer, particularly on massively parallel MIMD computers is disclosed. Global load balancing is achieved by overlapping neighborhoods of processors, where each neighborhood performs local load balancing. The method supports a large class of finite element and finite difference based applications and provides an automatic element management system to which applications are easily integrated. 13 figs.

CNT-based Thermal Interface Materials for Load-Bearing Aerospace Applications

DTIC Science & Technology

2012-08-01

CNT -based Thermal Interface Materials for Load-Bearing Aerospace Applications Michael Bifano, Pankaj Kaul and Vikas Prakash (PI) Department...4. TITLE AND SUBTITLE CNT -based Thermal Interface Materials for Load-Bearing Aerospace Applications 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c...Z39-18 Objective Develop multifunctional CNT -epoxy Thermal Interface Materials (TIMs) for load bearing aerospace applications. Emphasis - To

A conceptual framework: redefining forest soil's critical acid loads under a changing climate.

PubMed

McNulty, Steven G; Boggs, Johnny L

2010-06-01

Federal agencies of several nations have or are currently developing guidelines for critical forest soil acid loads. These guidelines are used to establish regulations designed to maintain atmospheric acid inputs below levels shown to damage forests and streams. Traditionally, when the critical soil acid load exceeds the amount of acid that the ecosystem can absorb, it is believed to potentially impair forest health. The excess over the critical soil acid load is termed the exceedance, and the larger the exceedance, the greater the risk of ecosystem damage. This definition of critical soil acid load applies to exposure of the soil to a single, long-term pollutant (i.e., acidic deposition). However, ecosystems can be simultaneously under multiple ecosystem stresses and a single critical soil acid load level may not accurately reflect ecosystem health risk when subjected to multiple, episodic environmental stress. For example, the Appalachian Mountains of western North Carolina receive some of the highest rates of acidic deposition in the eastern United States, but these levels are considered to be below the critical acid load (CAL) that would cause forest damage. However, the area experienced a moderate three-year drought from 1999 to 2002, and in 2001 red spruce (Picea rubens Sarg.) trees in the area began to die in large numbers. The initial survey indicated that the affected trees were killed by the southern pine beetle (Dendroctonus frontalis Zimm.). This insect is not normally successful at colonizing these tree species because the trees produce large amounts of oleoresin that exclude the boring beetles. Subsequent investigations revealed that long-term acid deposition may have altered red spruce forest structure and function. There is some evidence that elevated acid deposition (particularly nitrogen) reduced tree water uptake potential, oleoresin production, and caused the trees to become more susceptible to insect colonization during the drought period. While the ecosystem was not in exceedance of the CAL, long-term nitrogen deposition pre-disposed the forest to other ecological stress. In combination, insects, drought, and nitrogen ultimately combined to cause the observed forest mortality. If any one of these factors were not present, the trees would likely not have died. This paper presents a conceptual framework of the ecosystem consequences of these interactions as well as limited plot level data to support this concept. Future assessments of the use of CAL studies need to account for multiple stress impacts to better understand ecosystem response. Published by Elsevier Ltd.

Repair Concepts as Design Constraints of a Stiffened Composite PRSEUS Panel

NASA Technical Reports Server (NTRS)

Przekop, Adam

2012-01-01

A design and analysis of a repair concept applicable to a stiffened thin-skin composite panel based on the Pultruded Rod Stitched Efficient Unitized Structure is presented. The concept is a bolted repair using metal components, so that it can easily be applied in the operational environment. The damage scenario considered is a midbay-to-midbay saw-cut with a severed stiffener, flange and skin. In a previous study several repair configurations were explored and their feasibility confirmed but refinement was needed. The present study revisits the problem under recently revised design requirements and broadens the suite of loading conditions considered. The repair assembly design is based on the critical tension loading condition and subsequently its robustness is verified for a pressure loading case. High fidelity modeling techniques such as mesh-independent definition of compliant fasteners, elastic-plastic material properties for metal parts and geometrically nonlinear solutions are utilized in the finite element analysis. The best repair design is introduced, its analysis results are presented and factors influencing the design are assessed and discussed.

Impulsive response of an automatic transmission system with multiple clearances: Formulation, simulation and experiment

NASA Astrophysics Data System (ADS)

Crowther, Ashley R.; Singh, Rajendra; Zhang, Nong; Chapman, Chris

2007-10-01

Impulsive responses in geared systems with multiple clearances are studied when the mean torque excitation and system load change abruptly, with application to a vehicle driveline with an automatic transmission. First, torsional lumped-mass models of the planetary and differential gear sets are formulated using matrix elements. The model is then reduced to address tractable nonlinear problems while successfully retaining the main modes of interest. Second, numerical simulations for the nonlinear model are performed for transient conditions and a typical driving situation that induces an impulsive behaviour simulated. However, initial conditions and excitation and load profiles have to be carefully defined before the model can be numerically solved. It is shown that the impacts within the planetary or differential gears may occur under combinations of engine, braking and vehicle load transients. Our analysis shows that the shaping of the engine transient by the torque converter before reaching the clearance locations is more critical. Third, a free vibration experiment is developed for an analogous driveline with multiple clearances and three experiments that excite different response regimes have been carried out. Good correlations validate the proposed methodology.

Energy issues in microwave food processing: A review of developments and the enabling potentials of solid-state power delivery.

PubMed

Atuonwu, J C; Tassou, S A

2018-01-23

The enormous magnitude and variety of microwave applications in household, commercial and industrial food processing creates a strong motivation for improving the energy efficiency and hence, sustainability of the process. This review critically assesses key energy issues associated with microwave food processing, focusing on previous energy performance studies, energy performance metrics, standards and regulations. Factors affecting energy-efficiency are categorised into source, load and source-load matching factors. This highlights the need for highly-flexible and controllable power sources capable of receiving real-time feedback on load properties, and effecting rapid control actions to minimise reflections, heating non-uniformities and other imperfections that lead to energy losses. A case is made for the use of solid-state amplifiers as alternatives to conventional power sources, magnetrons. By a full-scale techno-economic analysis, including energy aspects, it is shown that the use of solid-state amplifiers as replacements to magnetrons is promising, not only from an energy and overall technical perspective, but also in terms of economics.

Effects of temperature, loading rate and nanowire length on torsional deformation and mechanical properties of aluminium nanowires investigated using molecular dynamics simulation

NASA Astrophysics Data System (ADS)

Sung, Po-Hsien; Wu, Cheng-Da; Fang, Te-Hua

2012-05-01

Single-crystal aluminium nanowires under torsion are studied using molecular dynamics simulations based on the many-body tight-binding potential. The effects of temperature, loading rate and nanowire length are evaluated in terms of atomic trajectories, potential energy, von Mises stress, a centrosymmetry parameter, torque, shear modulus and radial distribution function. Simulation results clearly show that torsional deformation begins at the surface, extends close to the two ends and finally diffuses to the middle part. The critical torsional angle which represents the beginning of plastic deformation varies with different conditions. Before the critical torsional angle is reached, the potential energy and the torque required for the deformation of a nanowire significantly increase with the torsional angle. The critical torsional angle increases with increasing nanowire length and loading rate and decreasing temperature. The torque required for the deformation decreases and the shear modulus increases with increasing nanowire length. For higher temperatures and higher loading rates, torsional buckling more easily occurs at the two ends of a nanowire, whereas it occurs towards the middle part at or below room temperature with lower loading rates. Geometry instability occurs before material instability (buckling) for a long nanowire.

Site-specific critical acid load estimates for forest soils in the Osborn Creek watershed, Michigan

Treesearch

Trevor Hobbs; Jason Lynch; Randy Kolka

2017-01-01

Anthropogenic acid deposition has the potential to accelerate leaching of soil cations, and in turn, deplete nutrients essential to forest vegetation. The critical load concept, employing a simple mass balance (SMB) approach, is often used to model this process. In an evaluation under the U.S. Forest Service Watershed Condition Framework program, soils in all 6th level...

Effect of ventilation rate and board loading on formaldehyde concentration : a critical review of the literature

Treesearch

George E. Myers

1984-01-01

A critical literature review has been carried out on the influence of ventilation rate (N, hr.-1) and board loading (L, m2/m3) on steady state formaldehyde concentrations (Cs, ppm) resulting from particleboard and plywood emissions. Large differences exist among boards in the extent to which their formaldehyde concentrations change with N or L in laboratory chambers....

Uncertainty analysis on simple mass balance model to calculate critical loads for soil acidity

Treesearch

Harbin Li; Steven G. McNulty

2007-01-01

Simple mass balance equations (SMBE) of critical acid loads (CAL) in forest soil were developed to assess potential risks of air pollutants to ecosystems. However, to apply SMBE reliably at large scales, SMBE must be tested for adequacy and uncertainty. Our goal was to provide a detailed analysis of uncertainty in SMBE so that sound strategies for scaling up CAL...

Assessing relationships between red spruce radial growth and pollution critical load exceedance values

Treesearch

Benjamin J. Engel; Paul G. Schaberg; Gary J. Hawley; Shelly A. Rayback; Jennifer Pontius; Alexandra M. Kosiba; Eric K. Miller

2016-01-01

Acidic sulfur (S) and nitrogen (N) deposition depletes cations such as calcium (Ca) from forest soils and has been linked to increases in foliar winter injury that led to the decline of red spruce (Picea rubens Sarg.) in the northeastern United States. We used results from a 30 m resolution steady-state S and N critical load exceedance model for New...

Thermoresponsive core-shell magnetic nanoparticles for combined modalities of cancer therapy.

PubMed

Purushotham, S; Chang, P E J; Rumpel, H; Kee, I H C; Ng, R T H; Chow, P K H; Tan, C K; Ramanujan, R V

2009-07-29

Thermoresponsive polymer-coated magnetic nanoparticles loaded with anti-cancer drugs are of considerable interest for novel multi-modal cancer therapies. Such nanoparticles can be used for magnetic drug targeting followed by simultaneous hyperthermia and drug release. Gamma-Fe(2)O(3) iron oxide magnetic nanoparticles (MNP) with average sizes of 14, 19 and 43 nm were synthesized by high temperature decomposition. Composite magnetic nanoparticles (CNP) of 43 nm MNP coated with the thermoresponsive polymer poly-n-isopropylacrylamide (PNIPAM) were prepared by dispersion polymerization of n-isopropylacrylamide monomer in the presence of the MNP. In vitro drug release of doxorubicin-(dox) loaded dehydrated CNP at temperatures below and above the lower critical solution temperature of PNIPAM (34 degrees C) revealed a weak dependence of drug release on swelling behavior. The particles displayed Fickian diffusion release kinetics; the maximum dox release at 42 degrees C after 101 h was 41%. In vitro simultaneous hyperthermia and drug release of therapeutically relevant quantities of dox was achieved, 14.7% of loaded dox was released in 47 min at hyperthermia temperatures. In vivo magnetic targeting of dox-loaded CNP to hepatocellular carcinoma (HCC) in a buffalo rat model was studied by magnetic resonance imaging (MRI) and histology. In summary, the good in vitro and in vivo performance of the doxorubicin-loaded thermoresponsive polymer-coated magnetic nanoparticles suggests considerable promise for applications in multi-modal treatment of cancer.

Projection Moire Interferometry for Rotorcraft Applications: Deformation Measurements of Active Twist Rotor Blades

NASA Technical Reports Server (NTRS)

Fleming, Gary A.; Soto, Hector L.; South, Bruce W.

2002-01-01

Projection Moire Interferometry (PMI) has been used during wind tunnel tests to obtain azimuthally dependent blade bending and twist measurements for a 4-bladed Active Twist Rotor (ATR) system in simulated forward flight. The ATR concept offers a means to reduce rotor vibratory loads and noise by using piezoelectric active fiber composite actuators embedded in the blade structure to twist each blade as they rotate throughout the rotor azimuth. The twist imparted on the blades for blade control causes significant changes in blade loading, resulting in complex blade deformation consisting of coupled bending and twist. Measurement of this blade deformation is critical in understanding the overall behavior of the ATR system and the physical mechanisms causing the reduction in rotor loads and noise. PMI is a non-contacting, video-based optical measurement technique capable of obtaining spatially continuous structural deformation measurements over the entire object surface within the PMI system field-of-view. When applied to rotorcraft testing, PMI can be used to measure the azimuth-dependent blade bending and twist along the full span of the rotor blade. This paper presents the PMI technique as applied to rotorcraft testing, and provides results obtained during the ATR tests demonstrating the PMI system performance. PMI measurements acquired at select blade actuation conditions generating minimum and maximum rotor loads are provided to explore the interrelationship between rotor loads, blade bending, and twist.

Magnus effects at high angles of attack and critical Reynolds numbers

NASA Technical Reports Server (NTRS)

Seginer, A.; Ringel, M.

1983-01-01

The Magnus force and moment experienced by a yawed, spinning cylinder were studied experimentally in low speed and subsonic flows at high angles of attack and critical Reynolds numbers. Flow-field visualization aided in describing a flow model that divides the Magnus phenomenon into a subcritical region, where reverse Magnus loads are experienced, and a supercritical region where these loads are not encountered. The roles of the spin rate, angle of attack, and crossflow Reynolds number in determining the boundaries of the subcritical region and the variations of the Magnus loads were studied.

Examining the Relationships of Different Cognitive Load Types Related to User Interface in Web-Based Instruction

ERIC Educational Resources Information Center

Cheon, Jongpil; Grant, Michael

2012-01-01

This study proposes a new instrument to measure cognitive load types related to user interface and demonstrates theoretical assumptions about different load types. In reconsidering established cognitive load theory, the inadequacies of the theory are criticized in terms of the adaption of learning efficiency score and distinction of cognitive load…

Axial buckling and transverse vibration of ultrathin nanowires: low symmetry and surface elastic effect

NASA Astrophysics Data System (ADS)

Lei, Xiao; Narsu, B.; Yun, Guohong; Li, Jiangang; Yao, Haiyan

2016-05-01

Surface effects play a deterministic role in the physical and mechanical properties of nanosized materials and structures. In this paper, we present a self-consistent theoretical scheme for describing the elasticity of nanowires. The natural frequency and the critical compression force of axial buckling are obtained analytically, taking into consideration the influences of lower symmetry, additional elastic parameters, surface reconstruction, surface elasticity, and residual surface stress. Applications of the present theory to elastic systems for the  <1 0 0 >  axially oriented Si and Cu nanowires and Ag  <1 1 0 >  axially oriented nanowires yield good agreement with experimental data and calculated results. The larger positive value of the new elastic parameter c12α taken into account for Si  <1 0 0 >  oriented nanowires drives the curves of natural frequency and critical compression force versus thickness towards the results obtained from density functional theory simulation. Negative surface stress decreases the critical load for axial buckling, thus making the nanowires very easy to bend into various structures. The present study is envisaged to provide useful insights for the design and application of nanowire-based devices.

Designing Crane Controls with Applied Mechanical and Electrical Safety Features

NASA Technical Reports Server (NTRS)

Lytle, Bradford P.; Walczak, Thomas A.

2002-01-01

The use of overhead traveling bridge cranes in many varied applications is common practice. In particular, the use of cranes in the nuclear, military, commercial, aerospace, and other industries can involve safety critical situations. Considerations for Human Injury or Casualty, Loss of Assets, Endangering the Environment, or Economic Reduction must be addressed. Traditionally, in order to achieve additional safety in these applications, mechanical systems have been augmented with a variety of devices. These devices assure that a mechanical component failure shall reduce the risk of a catastrophic loss of the correct and/or safe load carrying capability. ASME NOG-1-1998, (Rules for Construction of Overhead and Gantry Cranes, Top Running Bridge, and Multiple Girder), provides design standards for cranes in safety critical areas. Over and above the minimum safety requirements of todays design standards, users struggle with obtaining a higher degree of reliability through more precise functional specifications while attempting to provide "smart" safety systems. Electrical control systems also may be equipped with protective devices similar to the mechanical design features. Demands for improvement of the cranes "control system" is often recognized, but difficult to quantify for this traditionally "mechanically" oriented market. Finite details for each operation must be examined and understood. As an example, load drift (or small motions) at close tolerances can be unacceptable (and considered critical). To meet these high functional demands encoders and other devices are independently added to control systems to provide motion and velocity feedback to the control drive. This paper will examine the implementation of Programmable Electronic Systems (PES). PES is a term this paper will use to describe any control system utilizing any programmable electronic device such as Programmable Logic Controllers (PLC), or an Adjustable Frequency Drive (AID) 'smart' programmable motion controller. Therefore the use of the term Programmable Electronic Systems (PES) is an encompassing description for a large spectrum of programmable electronic control devices.

Gearbox Reliability Collaborative Investigation of Gearbox Motion and High-Speed-Shaft Loads

DOE Office of Scientific and Technical Information (OSTI.GOV)

Keller, Jon; Guo, Yi; Sethuraman, Latha

2016-03-18

This paper extends a model-to-test validation effort to examine the effect of different constant rotor torque and moment conditions and intentional generator misalignment on the gearbox motion and high-speed-shaft loads. Fully validating gearbox motion and high-speed-shaft loads across a range of test conditions is a critical precursor to examining the bearing loads, as the gearbox motion and high-speed-shaft loads are the drivers of these bearing loads.

Current and Future Deposition of Reactive Nitrogen to United States National Parks

NASA Astrophysics Data System (ADS)

Ellis, R.; Jacob, D. J.; Zhang, L.; Payer, M.; Holmes, C. D.; Schichtel, B. A.

2012-12-01

The concentrations of reactive nitrogen species in the atmosphere have been altered by anthropogenic activities such as fossil fuel combustion and agriculture. The United States National Parks are protected areas wherein the natural habitat is to be conserved for future generations. However, deposition of reactive nitrogen (N) to terrestrial and aquatic ecosystems can lead to changes, some of which may not be reversible. We investigate the deposition of N to U.S. National Parks using the GEOS-Chem chemical transport model with 0.5 x 0.667 degree resolution over North America. We compare the annual nitrogen deposition for each park to a critical load, above which significant harmful effects on specific ecosystem elements are likely to occur. For our base year 2006, we find 9 parks to be in exceedance of their critical load, mainly located in the east where N deposition can reach up to 25 kg N per hectare per year. Future changes in N deposition are also investigated using the IPCC Representative Concentration Pathway (RCP) emission scenarios for 2050. We use RCP8.5 as a "business-as-usual" scenario for N deposition and find that under this emission scenario, 18 parks are predicted to be in exceedance of their critical loads by the year 2050. Most of this increase in N deposition is due to increases in the emissions of ammonia. RCP4.5 was used as a more optimistic scenario but we still find 12 parks in exceedance of their critical loads. This work suggests that in order to meet N deposition critical load goals in U.S. National Parks, policy-makers should consider regulations on ammonia.

Is the "sterile cockpit" concept applicable to cardiovascular surgery critical intervals or critical events? The impact of protocol-driven communication during cardiopulmonary bypass.

PubMed

Wadhera, Rishi K; Parker, Sarah Henrickson; Burkhart, Harold M; Greason, Kevin L; Neal, James R; Levenick, Katherine M; Wiegmann, Douglas A; Sundt, Thoralf M

2010-02-01

There is general enthusiasm for applying strategies from aviation directly to medical care; the application of the "sterile cockpit" rule to surgery has accordingly been suggested. An implicit prerequisite to the evidence-based transfer of such a concept to the clinical domain, however, is definition of periods of high mental workload analogous to takeoff and landing. We measured cognitive demands among operating room staff, mapped critical events, and evaluated protocol-driven communication. With the National Aeronautics and Space Administration Task Load Index and semistructured focus groups, we identified common critical stages of cardiac surgical cases. Intraoperative communication was assessed before (n = 18) and after (n = 16) introduction of a structured communication protocol. Cognitive workload measures demonstrated high temporal diversity among caregivers in various roles. Eight critical events during cardiopulmonary bypass were then defined. A structured, unambiguous verbal communication protocol for these events was then implemented. Observations of 18 cases before implementation including 29.6 hours of cardiopulmonary bypass with 632 total communication exchanges (average 35.1 exchanges/case) were compared with observations of 16 cases after implementation including 23.9 hours of cardiopulmonary bypass with 748 exchanges (average 46.8 exchanges/case, P = .06). Frequency of communication breakdowns per case decreased significantly after implementation (11.5 vs 7.3 breakdowns/case, P = .008). Because of wide variations is cognitive workload among caregivers, effective communication can be structured around critical events rather than defined intervals analogous to the sterile cockpit, with reduction in communication breakdowns. 2010 The American Association for Thoracic Surgery. Published by Mosby, Inc. All rights reserved.

In vivo evaluation of a simvastatin-loaded nanostructured lipid carrier for bone tissue regeneration

NASA Astrophysics Data System (ADS)

Yue, Xinxin; Niu, Mao; Zhang, Te; Wang, Cheng; Wang, Zhonglei; Wu, Wangxi; Zhang, Qi; Lai, Chunhua; Zhou, Lei

2016-03-01

Alveolar bone loss has long been a challenge in clinical dental implant therapy. Simvastatin (SV) has been demonstrated to exert excellent anabolic effects on bone. However, the successful use of SV to increase bone formation in vivo largely depends on the local concentration of SV at the site of action, and there have been continuing efforts to develop an appropriate delivery system. Specifically, nanostructured lipid carrier (NLC) systems have become a popular type of encapsulation carrier system. Therefore, SV-loaded NLCs (SNs) (179.4 nm in diameter) were fabricated in this study, and the osteogenic effect of the SNs was evaluated in a critical-sized rabbit calvarial defect. Our results revealed that the SNs significantly enhanced bone formation in vivo, as evaluated by hematoxylin and eosin (HE) staining, immunohistochemistry, and a fluorescence analysis. Thus, this novel nanostructured carrier system could be a potential encapsulation carrier system for SV in bone regeneration applications.

The Relationship Between Constraint and Ductile Fracture Initiation as Defined by Micromechanical Analyses

NASA Technical Reports Server (NTRS)

Panontin, Tina L.; Sheppard, Sheri D.

1994-01-01

The use of small laboratory specimens to predict the integrity of large, complex structures relies on the validity of single parameter fracture mechanics. Unfortunately, the constraint loss associated with large scale yielding, whether in a laboratory specimen because of its small size or in a structure because it contains shallow flaws loaded in tension, can cause the breakdown of classical fracture mechanics and the loss of transferability of critical, global fracture parameters. Although the issue of constraint loss can be eliminated by testing actual structural configurations, such an approach can be prohibitively costly. Hence, a methodology that can correct global fracture parameters for constraint effects is desirable. This research uses micromechanical analyses to define the relationship between global, ductile fracture initiation parameters and constraint in two specimen geometries (SECT and SECB with varying a/w ratios) and one structural geometry (circumferentially cracked pipe). Two local fracture criteria corresponding to ductile fracture micromechanisms are evaluated: a constraint-modified, critical strain criterion for void coalescence proposed by Hancock and Cowling and a critical void ratio criterion for void growth based on the Rice and Tracey model. Crack initiation is assumed to occur when the critical value in each case is reached over some critical length. The primary material of interest is A516-70, a high-hardening pressure vessel steel sensitive to constraint; however, a low-hardening structural steel that is less sensitive to constraint is also being studied. Critical values of local fracture parameters are obtained by numerical analysis and experimental testing of circumferentially notched tensile specimens of varying constraint (e.g., notch radius). These parameters are then used in conjunction with large strain, large deformation, two- and three-dimensional finite element analyses of the geometries listed above to predict crack initiation loads and to calculate the associated (critical) global fracture parameters. The loads are verified experimentally, and microscopy is used to measure pre-crack length, crack tip opening displacement (CTOD), and the amount of stable crack growth. Results for A516-70 steel indicate that the constraint-modified, critical strain criterion with a critical length approximately equal to the grain size (0.0025 inch) provides accurate predictions of crack initiation. The critical void growth criterion is shown to considerably underpredict crack initiation loads with the same critical length. The relationship between the critical value of the J-integral for ductile crack initiation and crack depth for SECT and SECB specimens has been determined using the constraint-modified, critical strain criterion, demonstrating that this micromechanical model can be used to correct in-plane constraint effects due to crack depth and bending vs. tension loading. Finally, the relationship developed for the SECT specimens is used to predict the behavior of circumferentially cracked pipe specimens.

The impact of occupational load carriage on carrier mobility: a critical review of the literature.

PubMed

Carlton, Simon D; Orr, Robin M

2014-01-01

Military personnel and firefighters are required to carry occupational loads and complete tasks in hostile and unpredictable environments where a lack of mobility may risk lives. This review critically examines the literature investigating the impacts of load carriage on the mobility of these specialist personnel. Several literature databases, reference lists, and subject matter experts were employed to identify relevant studies. Studies meeting the inclusion criteria were critiqued using the Downs and Black protocol. Inter-rater agreement was determined by Cohen's κ. Twelve original research studies, which included male and female participants from military and firefighting occupations, were critiqued (κ = .81). A review of these papers found that as the carried load weight increased, carrier mobility during aerobic tasks (like road marching) and anaerobic tasks (like obstacle course negotiation) decreased. As such, it can be concluded that the load carried by some specialist personnel may increase their occupational risk by reducing their mobility.

Full Body Loading for Small Exercise Devices Project

NASA Technical Reports Server (NTRS)

Downs, Meghan; Hanson, Andrea; Newby, Nathaniel

2015-01-01

Protecting astronauts' spine, hip, and lower body musculoskeletal strength will be critical to safely and efficiently perform physically demanding vehicle egress, exploration, and habitat building activities necessary to expand human presence in the solar system. Functionally limiting decrements in musculoskeletal health are likely during Mars proving-ground and Earth-independent missions given extended transit times and the vehicle limitations for exercise devices (low-mass, small volume). Most small exercise device concepts are designed with single-cable loading, which inhibits the ability to perform full body exercises requiring two-point loading at the shoulders. Shoulder loading is critical to protect spine, hip, and lower body musculoskeletal strength. We propose a novel low-mass, low-maintenance, and rapid deploy pulley-based system that can attach to a single-cable small exercise device to enable two-point loading at the shoulders. This attachment could protect astronauts' health and save cost, space, and energy during all phases of the Journey to Mars.

C3 toxin and poly-DL-lactide-ε-caprolactone conduits in the critically damaged peripheral nervous system: a combined therapeutic approach.

PubMed

Leibig, Nico; Boyle, Veronika; Kraus, Daniel; Stark, Gerhard Bjoern; Penna, Vincenzo

2015-03-01

Peripheral nerve regeneration over longer distances through conduits is limited. In the presented study, critical size nerve gap bridging with a poly-DL-lactide-ε-caprolactone (PLC) conduit was combined with application of C3 toxin to facilitate axonal sprouting. The PLC filled with fibrin (n = 10) and fibrin gel loaded with 1-μg C3-C2I and 2-μg C2II (n = 10) were compared to autologous nerve grafts (n = 10) in a 15-mm sciatic nerve gap lesion model of the rat. Functional and electrophysiological analyses were performed before histological evaluation. Evaluation of motor function and nerve conduction velocity at 16 weeks revealed no differences between the groups. All histological parameters and muscle weight were significantly elevated in nerve graft group. No differences were observed in both PLC groups. The PLCs are permissive for nerve regeneration over a 15-mm defect in rats. Intraluminal application of C3 toxin did not lead to significant enhancement of nerve sprouting.

Biodegradable Orthopedic Magnesium-Calcium (MgCa) Alloys, Processing, and Corrosion Performance.

PubMed

Salahshoor, Meisam; Guo, Yuebin

2012-01-09

Magnesium-Calcium (Mg-Ca) alloy has received considerable attention as an emerging biodegradable implant material in orthopedic fixation applications. The biodegradable Mg-Ca alloys avoid stress shielding and secondary surgery inherent with permanent metallic implant materials. They also provide sufficient mechanical strength in load carrying applications as opposed to biopolymers. However, the key issue facing a biodegradable Mg-Ca implant is the fast corrosion in the human body environment. The ability to adjust degradation rate of Mg-Ca alloys is critical for the successful development of biodegradable orthopedic implants. This paper focuses on the functions and requirements of bone implants and critical issues of current implant biomaterials. Microstructures and mechanical properties of Mg-Ca alloys, and the unique properties of novel magnesium-calcium implant materials have been reviewed. Various manufacturing techniques to process Mg-Ca based alloys have been analyzed regarding their impacts on implant performance. Corrosion performance of Mg-Ca alloys processed by different manufacturing techniques was compared. In addition, the societal and economical impacts of developing biodegradable orthopedic implants have been emphasized.

Biodegradable Orthopedic Magnesium-Calcium (MgCa) Alloys, Processing, and Corrosion Performance

PubMed Central

Salahshoor, Meisam; Guo, Yuebin

2012-01-01

Magnesium-Calcium (Mg-Ca) alloy has received considerable attention as an emerging biodegradable implant material in orthopedic fixation applications. The biodegradable Mg-Ca alloys avoid stress shielding and secondary surgery inherent with permanent metallic implant materials. They also provide sufficient mechanical strength in load carrying applications as opposed to biopolymers. However, the key issue facing a biodegradable Mg-Ca implant is the fast corrosion in the human body environment. The ability to adjust degradation rate of Mg-Ca alloys is critical for the successful development of biodegradable orthopedic implants. This paper focuses on the functions and requirements of bone implants and critical issues of current implant biomaterials. Microstructures and mechanical properties of Mg-Ca alloys, and the unique properties of novel magnesium-calcium implant materials have been reviewed. Various manufacturing techniques to process Mg-Ca based alloys have been analyzed regarding their impacts on implant performance. Corrosion performance of Mg-Ca alloys processed by different manufacturing techniques was compared. In addition, the societal and economical impacts of developing biodegradable orthopedic implants have been emphasized. PMID:28817036

Ferroelectric Phase Transformations for Energy Conversion and Storage Applications

NASA Astrophysics Data System (ADS)

Jo, Hwan Ryul

Ferroelectric materials possess a spontaneous polarization and actively respond to external mechanical, electrical, and thermal loads. Due to their coupled behavior, ferroelectric materials are used in products such as sensors, actuators, detectors, and transducers. However, most current applications rely on low-energy conversion that involves low magnitude fields. They utilize the low-field linear properties of ferroelectric materials (piezoelectric, pyroelectric) and do not take full advantage of the large-field nonlinear behavior (irreversible domain wall motion, phase transformations) that can occur in ferroelectric materials. When external fields exceed a certain critical level, a structural transformation of the crystal can occur. These phase transformations are accompanied by a much larger response than the linear piezoelectric and pyroelectric responses, by as much as a multiple of ten times in the magnitude. This makes the non-linear behavior in ferroelectric materials promising for energy harvesting and energy storage technologies which will benefit from large-energy conversion. Yet, the ferroelectric phase transformation behavior under large external fields have been less studied and only a few studies have been directed at utilizing this large material response in applications. This dissertation addresses the development ferroelectric phase transformation-based applications, with particular focus on the materials. Development of the ferroelectric phase transformation-based applications was approached in several steps. First, the phase transformation behavior was fully characterized and understood by measuring the phase transformation responses under mechanical, electrical, thermal, and combined loads. Once the behavior was well characterized, systems level applications were addressed. This required assessing the effect of the phase transformation behavior on system performance. The performance of ferroelectric devices is strongly dependent on material properties and phase transformation behavior which can be tailored by modifying the chemical composition, processing conditions, and the loading history (poling). This results in optimization of system performance by tailoring material properties and phase transformation behavior. This approach applied to three ferroelectric phase transformation-based applications: 1. Ferroelectric energy generation 2. Ferroelectric high-energy storage capacitor 3. Ferroelectric thermal energy harvesting. This dissertation has addressed tuning the large field properties for phase transformation-based systems.

Adhesives: Test Method, Group Assignment, and Categorization Guide for High-Loading Rate Applications - History and Rationale

DTIC Science & Technology

2017-04-20

Categorization Guide for High -Loading- Rate Applications – History and Rationale by Robert Jensen, David Flanagan, Daniel DeSchepper, and Charles...Adhesives: Test Method, Group Assignment, and Categorization Guide for High -Loading- Rate Applications – History and Rationale by Robert Jensen...Categorization Guide for High - Loading-Rate Applications – History and Rationale 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6

Real time acousto-ultrasonic NDE technique for monitoring damage in ceramic composites under dynamic loads

NASA Technical Reports Server (NTRS)

Tiwari, Anil

1995-01-01

Research effort was directed towards developing a near real-time, acousto-ultrasonic (AU), nondestructive evaluation (NDE) tool to study the failure mechanisms of ceramic composites. Progression of damage is monitored in real-time by observing the changes in the received AU signal during the actual test. During the real-time AU test, the AU signals are generated and received by the AU transducers attached to the specimen while it is being subjected to increasing quasi-static loads or cyclic loads (10 Hz, R = 1.0). The received AU signals for 64 successive pulses were gated in the time domain (T = 40.96 micro sec) and then averaged every second over ten load cycles and stored in a computer file during fatigue tests. These averaged gated signals are representative of the damage state of the specimen at that point of its fatigue life. This is also the first major attempt in the development and application of real-time AU for continuously monitoring damage accumulation during fatigue without interrupting the test. The present work has verified the capability of the AU technique to assess the damage state in silicon carbide/calcium aluminosilicate (SiC/CAS) and silicon carbide/ magnesium aluminosilicate (SiC/MAS) ceramic composites. Continuous monitoring of damage initiation and progression under quasi-static ramp loading in tension to failure of unidirectional and cross-ply SiC/CAS and quasi-isotropic SiC/MAS ceramic composite specimens at room temperature was accomplished using near real-time AU parameters. The AU technique was shown to be able to detect the stress levels for the onset and saturation of matrix cracks, respectively. The critical cracking stress level is used as a design stress for brittle matrix composites operating at elevated temperatures. The AU technique has found that the critical cracking stress level is 10-15% below the level presently obtained for design purposes from analytical models. An acousto-ultrasonic stress-strain response (AUSSR) model for unidirectional and cross-ply ceramic composites was formulated. The AUSSR model predicts the strain response to increasing stress levels using real-time AU data and classical laminated plate theory. The Weibull parameters of the AUSSR model are used to calculate the design stress for thermo-structural applications. Real-time AU together with the AUSSR model was used to study the failure mechanisms of SiC/CAS ceramic composites under static and fatigue loading. An S-N curve was generated for a cross-ply SiC/CAS ceramic composite material. The AU results are corroborated and complemented by other NDE techniques, namely, in-situ optical microscope video recordings and edge replication.

Simple Formulas and Results for Buckling-Resistance and Stiffness Design of Compression-Loaded Laminated-Composite Cylinders

NASA Technical Reports Server (NTRS)

Nemeth, Michael P.; Mikulas, Martin M., Jr.

2009-01-01

Simple formulas for the buckling stress of homogeneous, specially orthotropic, laminated-composite cylinders are presented. The formulas are obtained by using nondimensional parameters and equations that facilitate general validation, and are validated against the exact solution for a wide range of cylinder geometries and laminate constructions. Results are presented that establish the ranges of the nondimensional parameters and coefficients used. General results, given in terms of the nondimensional parameters, are presented that encompass a wide range of geometries and laminate constructions. These general results also illustrate a wide spectrum of behavioral trends. Design-oriented results are also presented that provide a simple, clear indication of laminate composition on critical stress, critical strain, and axial stiffness. An example is provided to demonstrate the application of these results to thin-walled column designs.

Characteristics of dynamic triaxial testing of asphalt mixtures

NASA Astrophysics Data System (ADS)

Ulloa Calderon, Alvaro

Due to the increasing traffic loads and tire pressures, a serious detrimental impact has occurred on flexible pavements in the form of excessive permanent deformation once the critical combination of loading and environmental conditions are reached. This distress, also known as rutting, leads to an increase in road roughness and ultimately jeopardizes the road users' safety. The flow number (FN) simple performance test for asphalt mixtures was one of the final three tests selected for further evaluation from the twenty-four test/material properties initially examined under the NCHRP 9-19 project. Currently, no standard triaxial testing conditions in terms of the magnitude of the deviator and confining stresses have been specified. In addition, a repeated haversine axial compressive load pulse of 0.1 second and a rest period of 0.9 second are commonly used as part of the triaxial testing conditions. The overall objective of this research was to define the loading conditions that created by a moving truck load in the hot mixed asphalt (HMA) layer. The loading conditions were defined in terms of the triaxial stress levels and the corresponding loading time. Dynamic mechanistic analysis with circular stress distribution was used to closely simulate field loading conditions. Extensive mechanistic analyses of three different asphalt pavement structures subjected to moving traffic loads at various speeds and under braking and non-braking conditions were conducted using the 3D-Move model. Prediction equations for estimating the anticipated deviator and confining stresses along with the equivalent deviator stress pulse duration as a function of pavement temperature, vehicle speed, and asphalt mixture's stiffness have been developed. The magnitude of deviator stress, sigmad and confining stress, sigmac, were determined by converting the stress tensor computed in the HMA layer at 2" below pavement surface under a moving 18-wheel truck using the octahedral normal and shear stresses. In addition, the characteristics of the loading pulse were determined by best-fitting a haversine wave shape for the equivalent triaxial deviator stress pulse. The tandem axle was proven to generate the most critical combination of deviator and confining stresses for braking and non-braking conditions at 2 inches below the pavement surface. Thus, this study is focused on developing the stress state and pulse characteristics required to determine the critical conditions on HMA mixtures under the loading of the tandem axle. An increase of 40% was observed in the deviator stress when braking conditions are incorporated. A preliminary validation of the recommended magnitudes for the deviator and confining stresses on a field mixture from WesTrack showed consistent results between the flow number test results and field performance. Based on laboratory experiments, the critical conditions of different field mixtures from the WesTrack project and also lab produced samples at different air-voids levels were determined. The results indicate that the tertiary stage will occur under the FN test when a combination of a critical temperature and a given loading conditions for specific air voids content occurs.

The Impact of Load Carriage on Measures of Power and Agility in Tactical Occupations: A Critical Review.

PubMed

Joseph, Aaron; Wiley, Amy; Orr, Robin; Schram, Benjamin; Dawes, J Jay

2018-01-07

The current literature suggests that load carriage can impact on a tactical officer's mobility, and that survival in the field may rely on the officer's mobility. The ability for humans to generate power and agility is critical for performance of the high-intensity movements required in the field of duty. The aims of this review were to critically examine the literature investigating the impacts of load carriage on measures of power and agility and to synthesize the findings. The authors completed a search of the literature using key search terms in four databases. After relevant studies were located using strict inclusion and exclusion criteria, the studies were critically appraised using the Downs and Black Checklist and relevant data were extracted and tabled. Fourteen studies were deemed relevant for this review, ranging in percentage quality scores from 42.85% to 71.43%. Outcome measures used in these studies to indicate levels of power and agility included short-distance sprints, vertical jumps, and agility runs, among others. Performance of both power and agility was shown to decrease when tactical load was added to the participants. This suggests that the increase in weight carried by tactical officers may put this population at risk of injury or fatality in the line of duty.

Impact of nitrogen deposition at the species level

PubMed Central

Payne, Richard J.; Dise, Nancy B.; Stevens, Carly J.; Gowing, David J.; Duprè, Cecilia; Dorland, Edu; Gaudnik, Cassandre; Bleeker, Albert; Diekmann, Martin; Alard, Didier; Bobbink, Roland; Fowler, David; Corcket, Emmanuel; Mountford, J. Owen; Vandvik, Vigdis; Aarrestad, Per Arild; Muller, Serge

2013-01-01

In Europe and, increasingly, the rest of the world, the key policy tool for the control of air pollution is the critical load, a level of pollution below which there are no known significant harmful effects on the environment. Critical loads are used to map sensitive regions and habitats, permit individual polluting activities, and frame international negotiations on transboundary air pollution. Despite their fundamental importance in environmental science and policy, there has been no systematic attempt to verify a critical load with field survey data. Here, we use a large dataset of European grasslands along a gradient of nitrogen (N) deposition to show statistically significant declines in the abundance of species from the lowest level of N deposition at which it is possible to identify a change. Approximately 60% of species change points occur at or below the range of the currently established critical load. If this result is found more widely, the underlying principle of no harm in pollution policy may need to be modified to one of informed decisions on how much harm is acceptable. Our results highlight the importance of protecting currently unpolluted areas from new pollution sources, because we cannot rule out ecological impacts from even relatively small increases in reactive N deposition. PMID:23271811

The Impact of Load Carriage on Measures of Power and Agility in Tactical Occupations: A Critical Review

PubMed Central

Joseph, Aaron; Wiley, Amy; Dawes, J. Jay

2018-01-01

The current literature suggests that load carriage can impact on a tactical officer’s mobility, and that survival in the field may rely on the officer’s mobility. The ability for humans to generate power and agility is critical for performance of the high-intensity movements required in the field of duty. The aims of this review were to critically examine the literature investigating the impacts of load carriage on measures of power and agility and to synthesize the findings. The authors completed a search of the literature using key search terms in four databases. After relevant studies were located using strict inclusion and exclusion criteria, the studies were critically appraised using the Downs and Black Checklist and relevant data were extracted and tabled. Fourteen studies were deemed relevant for this review, ranging in percentage quality scores from 42.85% to 71.43%. Outcome measures used in these studies to indicate levels of power and agility included short-distance sprints, vertical jumps, and agility runs, among others. Performance of both power and agility was shown to decrease when tactical load was added to the participants. This suggests that the increase in weight carried by tactical officers may put this population at risk of injury or fatality in the line of duty. PMID:29316674

Spatial buckling analysis of current-carrying nanowires in the presence of a longitudinal magnetic field accounting for both surface and nonlocal effects

NASA Astrophysics Data System (ADS)

Foroutan, Shahin; Haghshenas, Amin; Hashemian, Mohammad; Eftekhari, S. Ali; Toghraie, Davood

2018-03-01

In this paper, three-dimensional buckling behavior of nanowires was investigated based on Eringen's Nonlocal Elasticity Theory. The electric current-carrying nanowires were affected by a longitudinal magnetic field based upon the Lorentz force. The nanowires (NWs) were modeled based on Timoshenko beam theory and the Gurtin-Murdoch's surface elasticity theory. Generalized Differential Quadrature (GDQ) method was used to solve the governing equations of the NWs. Two sets of boundary conditions namely simple-simple and clamped-clamped were applied and the obtained results were discussed. Results demonstrated the effect of electric current, magnetic field, small-scale parameter, slenderness ratio, and nanowires diameter on the critical compressive buckling load of nanowires. As a key result, increasing the small-scale parameter decreased the critical load. By the same token, increasing the electric current, magnetic field, and slenderness ratio resulted in a decrease in the critical load. As the slenderness ratio increased, the effect of nonlocal theory decreased. In contrast, by expanding the NWs diameter, the nonlocal effect increased. Moreover, in the present article, the critical values of the magnetic field of strength and slenderness ratio were revealed, and the roles of the magnetic field, slenderness ratio, and NWs diameter on higher buckling loads were discussed.

Effects and empirical critical loads of Nitrogen for ecoregions of the United States

USGS Publications Warehouse

Pardo, Linda H.; Robin-Abbott, Molly J.; Fenn, Mark E.; Goodale, Christine L.; Geiser, Linda H.; Driscoll, Charles T.; Allen, Edith B.; Baron, Jill S.; Bobbink, Roland; Bowman, William D.; Clark, C M; Emmett, B.; Gilliam, Frank S; Greaver, Tara L.; Hall, Sharon J; Lilleskov, Erik A.; Liu, Lingli; Lynch, Jason A.; Nadelhoffer, Knute J; Perakis, Steven; Stoddard, John L; Weathers, Kathleen C.; Dennis, Robin L.

2015-01-01

Human activity in the last century has increased nitrogen (N) deposition to a level that has caused or is likely to cause alterations to the structure and function of many ecosystems across the United States. We synthesized current research relating atmospheric N deposition to effects on terrestrial and freshwater ecosystems in the United States, and estimated associated empirical critical loads of N for several receptors: freshwater diatoms, mycorrhizal fungi, lichens, bryophytes, herbaceous plants, shrubs, and trees. Biogeochemical responses included increased N mineralization and nitrification, increased gaseous N losses, and increased N leaching. Individual species, population, and community responses included increased tissue N, physiological and nutrient imbalances, increased growth, altered root-shoot ratios, increased susceptibility to secondary stresses, altered fire regime, shifts in competitive interactions and community composition, changes in species richness and other measures of biodiversity, and increases in invasive species. The range of critical loads of nutrient N reported for U.S. ecoregions, inland surface waters, and freshwater wetlands is 1–39 kg N ha−1 yr−1, spanning the range of N deposition observed over most of the country. The empirical critical loads of N tend to increase in the following sequence: diatoms, lichens and bryophytes, mycorrhizal fungi, herbaceous plants and shrubs, trees.

14 CFR 23.787 - Baggage and cargo compartments.

Code of Federal Regulations, 2010 CFR

2010-01-01

... AIRCRAFT AIRWORTHINESS STANDARDS: NORMAL, UTILITY, ACROBATIC, AND COMMUTER CATEGORY AIRPLANES Design and... critical load distributions at the appropriate maximum load factors corresponding to the flight and ground...

Structural and elastic properties and stability characteristics of oxygenated carbon nanotubes under physical adsorption of polymers

NASA Astrophysics Data System (ADS)

Ansari, R.; Ajori, S.; Rouhi, S.

2015-03-01

The importance of covalent and non-covalent functionalization approaches for modification the properties of carbon nanotubes is being more widely recognized. To this end, elastic properties and buckling behavior of oxygenated CNT with atomic oxygen and hydroxyl under physical adsorption of PE (Polyethylene) and PEO (Poly (ethylene oxide)) are determined through employing the molecular dynamics (MD) simulations. The results demonstrate that non-covalent bonding of polymer on the surface of oxygenated CNT causes reductions in the variations of critical buckling load and critical strain compared to oxygenated CNTs. Critical buckling load and critical strain of oxygenated CNT/polymer are higher than those of oxygenated CNT. Also, it is demonstrated that critical buckling load and critical strain values in the case of oxygenated CNT/polymer are independent of polymer type unlike the value of Young's modulus. It is shown that variations of Young's modulus decrease as PE adsorbed on the surface of oxygenated CNT. Moreover, the presence of oxygen atom on PEO chain leads to bigger variations of Young's modulus with weight percentage of chemisorbed component, i.e. atomic oxygen and hydroxyl. It is also demonstrated that Young's modulus reduces more considerably in the presence of PEO chain compared to PE one.

Criticality conditions of heterogeneous energetic materials under shock loading

NASA Astrophysics Data System (ADS)

Nassar, Anas; Rai, Nirmal Kumar; Sen, Oishik; Udaykumar, H. S.

2017-06-01

Shock interaction with the microstructural heterogeneities of energetic materials can lead to the formation of locally heated regions known as hot spots. These hot spots are the potential sites where chemical reaction may be initiated. However, the ability of a hot spot to initiate chemical reaction depends on its size, shape and strength (temperature). Previous study by Tarver et al. has shown that there exists a critical size and temperature for a given shape (spherical, cylindrical, and planar) of the hot spot above which reaction initiation is imminent. Tarver et al. assumed a constant temperature variation in the hot spot. However, the meso-scale simulations show that the temperature distribution within a hot spot formed from processes such as void collapse is seldom constant. Also, the shape of a hot spot can be arbitrary. This work is an attempt towards development of a critical hot spot curve which is a function of loading strength, duration and void morphology. To achieve the aforementioned goal, mesoscale simulations are conducted on porous HMX material. The process is repeated for different loading conditions and void sizes. The hot spots formed in the process are examined for criticality depending on whether they will ignite or not. The metamodel is used to obtain criticality curves and is compared with the critical hot spot curve of Tarver et al.

ARES I-X USS Fracture Analysis Loads Spectra Development

NASA Technical Reports Server (NTRS)

Larsen, Curtis; Mackey, Alden

2008-01-01

This report describes the development of a set of bounding load spectra for the ARES I-X launch vehicle. These load spectra are used in the determination of the critical initial flaw size (CIFS) of the welds in the ARES I-X upper stage simulator (USS).

From the elastica compass to the elastica catapult: an essay on the mechanics of soft robot arm

PubMed Central

Armanini, C.; Dal Corso, F.; Misseroni, D.

2017-01-01

An elastic rod is clamped at one end and has a dead load attached to the other (free) end. The rod is then slowly rotated using the clamp. When the load is smaller than the buckling value, the rod describes a continuous set of quasi-static forms and its end traces a (smooth, convex and simple) closed curve, which would be a circle if the rod were rigid. The closed curve is analytically determined through the integration of the Euler’s elastica, so that for sufficiently small loads the mechanical system behaves as an ‘elastica compass’. For loads higher than that of buckling, the elastica reaches a configuration from which a snap-back instability occurs, realizing a sort of ‘elastica catapult’. The whole quasi-static evolution leading to the critical configuration for snapping is calculated through the elastica and the subsequent dynamic motion simulated using two numerical procedures, one ad hoc developed and another based on a finite-element scheme. The theoretical results are then validated on a specially designed and built apparatus. An obvious application of the present model would be in the development of soft robotic limbs, but the results are also of interest for the optimization analysis in pole vaulting. PMID:28293144

From the elastica compass to the elastica catapult: an essay on the mechanics of soft robot arm.

PubMed

Armanini, C; Dal Corso, F; Misseroni, D; Bigoni, D

2017-02-01

An elastic rod is clamped at one end and has a dead load attached to the other (free) end. The rod is then slowly rotated using the clamp. When the load is smaller than the buckling value, the rod describes a continuous set of quasi-static forms and its end traces a (smooth, convex and simple) closed curve, which would be a circle if the rod were rigid. The closed curve is analytically determined through the integration of the Euler's elastica, so that for sufficiently small loads the mechanical system behaves as an 'elastica compass'. For loads higher than that of buckling, the elastica reaches a configuration from which a snap-back instability occurs, realizing a sort of 'elastica catapult'. The whole quasi-static evolution leading to the critical configuration for snapping is calculated through the elastica and the subsequent dynamic motion simulated using two numerical procedures, one ad hoc developed and another based on a finite-element scheme. The theoretical results are then validated on a specially designed and built apparatus. An obvious application of the present model would be in the development of soft robotic limbs, but the results are also of interest for the optimization analysis in pole vaulting.

Production of GMP-grade radioactive holmium loaded poly(L-lactic acid) microspheres for clinical application.

PubMed

Zielhuis, S W; Nijsen, J F W; de Roos, R; Krijger, G C; van Rijk, P P; Hennink, W E; van het Schip, A D

2006-03-27

Radioactive holmium-166 loaded poly(L-lactic acid) microspheres are promising systems for the treatment of liver malignancies. The microspheres are loaded with holmium acetylacetonate (HoAcAc) and prepared by a solvent evaporation method. After preparation, the microspheres (Ho-PLLA-MS) are activated by neutron irradiation in a nuclear reactor. In this paper, the aspects of the production of a (relatively) large-scale GMP batch (4 g, suitable for treatment of 5-10 patients) of Ho-PLLA-MS are described. The critical steps of the Ho-PLLA-MS production process (sieving procedure, temperature control during evaporation and raw materials) were considered and the pharmaceutical quality of the microspheres was evaluated. The pharmaceutical characteristics (residual solvents, possible bacterial contaminations and endotoxins) of the produced Ho-PLLA-MS batches were in compliance with the requirements of the European Pharmacopoeia. Moreover, neutron irradiated Ho-PLLA-MS retained their morphological integrity and the holmium remained stably associated with the microspheres; it was observed that after 270h (10 times the half-life of Ho-166) only 0.3+/-0.1% of the loading was released from the microspheres in an aqueous solution. In conclusion, Ho-PLLA-MS which are produced as described in this paper, can be clinically applied, with respect to their pharmaceutical quality.

Analysis of resonance mechanism and conditions of train bridge system

NASA Astrophysics Data System (ADS)

Xia, H.; Zhang, N.; Guo, W. W.

2006-11-01

In this paper, the resonance mechanism and conditions of train-bridge system are investigated through theoretical derivations, numerical simulations and experimental data analyses. The resonant responses of the bridge induced by moving trains are classified into three types according to different resonance mechanisms: the first is related to the periodical actions of moving load series of the vertical weights, lateral centrifugal and wind forces of vehicles; the second is induced by the loading rate of moving load series of vehicles; the third is owing to the periodically loading of the swing forces of the train vehicles excited by track irregularities and wheel hunting movements. The vehicle resonance is induced by the periodical action of regular arrangement of bridge spans and their deflections. The resonant conditions are proposed and the corresponding resonant train speeds are determined. The application scopes of resonance conditions are discussed. The resonance of the train-bridge system is affected by the span, total length, lateral and vertical stiffness of the bridge, the compositions of the train, and the axle arrangements and natural frequencies of the vehicles. The resonant train speeds for some bridges are estimated and are compared with the critical train speeds obtained from the dynamic simulation of train-bridge interaction model or from the field measurements.

Identification of critical equipment and determination of operational limits in helium refrigerators under pulsed heat load

NASA Astrophysics Data System (ADS)

Dutta, Rohan; Ghosh, Parthasarathi; Chowdhury, Kanchan

2014-01-01

Large-scale helium refrigerators are subjected to pulsed heat load from tokamaks. As these plants are designed for constant heat loads, operation under such varying load may lead to instability in plants thereby tripping the operation of different equipment. To understand the behavior of the plant subjected to pulsed heat load, an existing plant of 120 W at 4.2 K and another large-scale plant of 18 kW at 4.2 K have been analyzed using a commercial process simulator Aspen Hysys®. A similar heat load characteristic has been applied in both quasi steady state and dynamic analysis to determine critical stages and equipment of these plants from operational point of view. It has been found that the coldest part of both the cycles consisting JT-stage and its preceding reverse Brayton stage are the most affected stages of the cycles. Further analysis of the above stages and constituting equipment revealed limits of operation with respect to variation of return stream flow rate resulted from such heat load variations. The observations on the outcome of the analysis can be used for devising techniques for steady operation of the plants subjected to pulsed heat load.

Instability-related delamination growth in thermoset and thermoplastic composites

NASA Technical Reports Server (NTRS)

Gillespie, John W., Jr.; Carlsson, Leif A.; Rothschilds, Robert J.

1988-01-01

Mixed-mode crack propagation in compressively loaded thermoset and thermoplastic composite columns with an imbedded through-width delamination is investigated. Beam theory is used to analyze the geometrically nonlinear load-deformation relationship of the delaminated subregion. The elastic restraint model (ERM), combined with existing FSM modeling of the crack-tip region, yields expressions for the Mode I and Mode II components of the strain energy release rate G(I) and G(II) to predict the critical load at the onset of delamination growth. Experimental data were generated for geometries yielding a wide range of G(I)/G(II) ratios at the onset of crack growth. A linear mixed-mode crack growth criterion in conjunctuion with the ERM provides good agreement between predicted and measured critical loads for both materials studied.

Buckling analysis of planar compression micro-springs

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhang, Jing; Sui, Li; Shi, Gengchen

2015-04-15

Large compression deformation causes micro-springs buckling and loss of load capacity. We analyzed the impact of structural parameters and boundary conditions for planar micro-springs, and obtained the change rules for the two factors that affect buckling. A formula for critical buckling deformation of micro-springs under compressive load was derived based on elastic thin plate theory. Results from this formula were compared with finite element analysis results but these did not always correlate. Therefore, finite element analysis is necessary for micro-spring buckling analysis. We studied the variation of micro-spring critical buckling deformation caused by four structural parameters using ANSYS software undermore » two constraint conditions. The simulation results show that when an x-direction constraint is added, the critical buckling deformation increases by 32.3-297.9%. The critical buckling deformation decreases with increase in micro-spring arc radius or section width and increases with increase in micro-spring thickness or straight beam width. We conducted experiments to confirm the simulation results, and the experimental and simulation trends were found to agree. Buckling analysis of the micro-spring establishes a theoretical foundation for optimizing micro-spring structural parameters and constraint conditions to maximize the critical buckling load.« less

Critical load: a novel approach to determining a sustainable intensity during resistance exercise.

PubMed

Arakelian, Vivian M; Mendes, Renata G; Trimer, Renata; Rossi Caruso, Flavia C; de Sousa, Nuno M; Borges, Vanessa C; do Valle Gomes Gatto, Camila; Baldissera, Vilmar; Arena, Ross; Borghi-Silva, Audrey

2017-05-01

A hyperbolic function as well as a linear relationship between power output and time to exhaustion (Tlim) has been consistently observed during dynamic non-resistive exercises. However, little is known about its concept to resistance exercises (RE), which could be defined as critical load (CL). This study aimed to verify the existence of CL during dynamic RE and to verify the number of workbouts necessary to determine the optimal modeling to achieve it. Fifteen healthy men (23±2.5 yrs) completed 1 repetition maximum test (1RM) on a leg press and 3 (60%, 75% and 90% of 1RM) or 4 (+ 30% of 1RM) workbouts protocols to obtain the CL by hyperbolic and linear regression models between Tlim and load performed. Blood lactate and leg fatigue were also measured. CL was obtained during RE and 3 workbouts protocol estimate it at 53% while 4 tests at 38% of 1 RM. However, based on coefficients of determination, 3 protocols provided a better fit than the 4-parameter model, respectively (R2>0.95 vs. >0.77). Moreover, all intensities increased blood lactate and leg fatigue, however, when corrected by Tlim, were significantly lower at CL. It was possible to determinate CL during dynamic lower limbs RE and that 3 exhaustive workbouts can be used to better estimate the CL, constituting a new concept of determining this threshold during dynamic RE and reducing the physically demanding nature of the protocol. These findings may have important applications for functional performance evaluation and prescription of RE programs.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kiselyov, V.A.; Sokov, L.M.

The LBB regulatory approach adopted in Russia in 1993 as an extra safety barrier is described for advanced WWER 1000 reactor steamline. The application of LBB concept requires the following additional protections. First, the steamline should be a highly qualified piping, performed in accordance with the applicable regulations and guidelines, carefully screened to verify that it is not subjected to any disqualifying failure mechanism. Second, a deterministic fracture mechanics analysis and leak rate evaluation have been performed to demonstrate that postulated through-wall crack that yields 95 1/min at normal operation conditions is stable even under seismic loads. Finally, it hasmore » been verified that the leak detection systems are sufficiently reliable, diverse and sensitive, and that adequate margins exist to detect a through wall crack smaller than the critical size. The obtained results are encouraging and show the possibility of the application of the LBB case to the steamline of advanced WWER 1000 reactor.« less

Carbon fiber composites application in ITER plasma facing components

NASA Astrophysics Data System (ADS)

Barabash, V.; Akiba, M.; Bonal, J. P.; Federici, G.; Matera, R.; Nakamura, K.; Pacher, H. D.; Rödig, M.; Vieider, G.; Wu, C. H.

1998-10-01

Carbon Fiber Composites (CFCs) are one of the candidate armour materials for the plasma facing components of the International Thermonuclear Experimental Reactor (ITER). For the present reference design, CFC has been selected as armour for the divertor target near the plasma strike point mainly because of unique resistance to high normal and off-normal heat loads. It does not melt under disruptions and might have higher erosion lifetime in comparison with other possible armour materials. Issues related to CFC application in ITER are described in this paper. They include erosion lifetime, tritium codeposition with eroded material and possible methods for the removal of the codeposited layers, neutron irradiation effect, development of joining technologies with heat sink materials, and thermomechanical performance. The status of the development of new advanced CFCs for ITER application is also described. Finally, the remaining R&D needs are critically discussed.

Designing User Interfaces for Smart-Applications for Operating Rooms and Intensive Care Units

NASA Astrophysics Data System (ADS)

Kindsmüller, Martin Christof; Haar, Maral; Schulz, Hannes; Herczeg, Michael

Today’s physicians and nurses working in operating rooms and intensive care units have to deal with an ever increasing amount of data. More and more medical devices are delivering information, which has to be perceived and interpreted in regard to patient status and the necessity to adjust therapy. The combination of high information load and insufficient usability creates a severe challenge for the health personnel with respect to proper monitoring of these devices respective to acknowledging alarms and timely reaction to critical incidents. Smart Applications are a new kind of decision support systems that incorporate medical expertise in order to help health personnel in regard to diagnosis and therapy. By means of a User Centered Design process of two Smart Applications (anaesthesia monitor display, diagnosis display), we illustrate which approach should be followed and which processes and methods have been successfully applied in fostering the design of usable medical devices.

Performance Enhancement Strategies for Multi-Block Overset Grid CFD Applications

NASA Technical Reports Server (NTRS)

Djomehri, M. Jahed; Biswas, Rupak

2003-01-01

The overset grid methodology has significantly reduced time-to-solution of highfidelity computational fluid dynamics (CFD) simulations about complex aerospace configurations. The solution process resolves the geometrical complexity of the problem domain by using separately generated but overlapping structured discretization grids that periodically exchange information through interpolation. However, high performance computations of such large-scale realistic applications must be handled efficiently on state-of-the-art parallel supercomputers. This paper analyzes the effects of various performance enhancement strategies on the parallel efficiency of an overset grid Navier-Stokes CFD application running on an SGI Origin2000 machinc. Specifically, the role of asynchronous communication, grid splitting, and grid grouping strategies are presented and discussed. Details of a sophisticated graph partitioning technique for grid grouping are also provided. Results indicate that performance depends critically on the level of latency hiding and the quality of load balancing across the processors.

Nanocarriers in therapy of infectious and inflammatory diseases

NASA Astrophysics Data System (ADS)

Ikoba, Ufuoma; Peng, Haisheng; Li, Haichun; Miller, Cathy; Yu, Chenxu; Wang, Qun

2015-02-01

Nanotechnology is a growing science that has applications in various areas of medicine. The composition of nanocarriers for drug delivery is critical to guarantee high therapeutic performance when targeting specific host sites. Applications of nanotechnology are prevalent in the diagnosis and treatment of infectious and inflammatory diseases. This review summarizes recent advancements in the application of nanotechnology to the therapy of infectious and inflammatory diseases. The major focus is on the design and fabrication of various nanomaterials, characteristics and physicochemical properties of drug-loaded nanocarriers, and the use of these nanoscale drug delivery systems in treating infectious and inflammatory diseases, such as AIDS, hepatitis, tuberculosis, melanoma, and representative inflammatory diseases. Clinical trials and future perspective of the use of nanocarriers are also discussed in detail. We hope that such a review will be valuable to researchers who are exploring nanoscale drug delivery systems for the treatment of specific infectious and inflammatory diseases.

In situ formation of magnetopolymersomes via electroporation for MRI

NASA Astrophysics Data System (ADS)

Bain, Jennifer; Ruiz-Pérez, Lorena; Kennerley, Aneurin J.; Muench, Stephen P.; Thompson, Rebecca; Battaglia, Giuseppe; Staniland, Sarah S.

2015-09-01

As the development of diagnostic/therapeutic (and combined: theranostic) nanomedicine grows, smart drug-delivery vehicles become ever more critical. Currently therapies consist of drugs tethered to, or encapsulated within nanoparticles or vesicles. There is growing interest in functionalising them with magnetic nanoparticles (MNPs) to target the therapeutics by localising them using magnetic fields. An alternating magnetic field induces remote heating of the particles (hyperthermia) triggering drug release or cell death. Furthermore, MNPs are diagnostic MRI contrast agents. There is considerable interest in MNP embedded vehicles for nanomedicine, but their development is hindered by difficulties producing consistently monodisperse MNPs and their reliable loading into vesicles. Furthermore, it is highly advantageous to "trigger" MNP production and to tune the MNP's size and magnetic response. Here we present the first example of a tuneable, switchable magnetic delivery vehicle for nanomedical application. These are comprised of robust, tailored polymer vesicles (polymersomes) embedded with superparamagnetic magnetite MNPs (magnetopolymersomes) which show good MRI contrast (R2* = 148.8 s-1) and have a vacant core for loading of therapeutics. Critically, the magnetopolymersomes are produced by a pioneering nanoreactor method whereby electroporation triggers the in situ formation of MNPs within the vesicle membrane, offering a switchable, tuneable magnetic responsive theranostic delivery vehicle.

Use of Combined Biogeochemical Model Approaches and Empirical Data to Assess Critical Loads of Nitrogen

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fenn, Mark E.; Driscoll, Charles; Zhou, Qingtao

2015-01-01

Empirical and dynamic biogeochemical modelling are complementary approaches for determining the critical load (CL) of atmospheric nitrogen (N) or other constituent deposition that an ecosystem can tolerate without causing ecological harm. The greatest benefits are obtained when these approaches are used in combination. Confounding environmental factors can complicate the determination of empirical CLs across depositional gradients, while the experimental application of N amendments for estimating the CL does not realistically mimic the effects of chronic atmospheric N deposition. Biogeochemical and vegetation simulation models can provide CL estimates and valuable ecosystem response information, allowing for past and future scenario testing withmore » various combinations of environmental factors, pollutants, pollutant control options, land management, and ecosystem response parameters. Even so, models are fundamentally gross simplifications of the real ecosystems they attempt to simulate. Empirical approaches are vital as a check on simulations and CL estimates, to parameterize models, and to elucidate mechanisms and responses under real world conditions. In this chapter, we provide examples of empirical and modelled N CL approaches in ecosystems from three regions of the United States: mixed conifer forest, desert scrub and pinyon- juniper woodland in California; alpine catchments in the Rocky Mountains; and lakes in the Adirondack region of New York state.« less

Behavior of a centrally notched cross-ply and unidirectional ceramic matrix composite in tension-compression fatigue. Master's thesis

DOE Office of Scientific and Technical Information (OSTI.GOV)

Weidenaar, W.A.

1992-12-01

Centrally notched (hole), cross-ply, ((0/90) sub 2) sub s, and unidirectional, (0) sub 8 laminates of Silicon Carbide fiber-reinforced Aluminosilicate glass, SiC/1723, were fatigue tested under tension-compression loading with a load ratio of -1. Damage accumulated continuously for both lay-ups, leading to eventual failure and a reduced fatigue life. Critical damage in the cross-ply consisted of longitudinal cracks in the 90 deg plies growing and combining with transverse cracks to effectively eliminate the 90 deg plies' load carrying capability and allowing the specimen to buckle. Critical damage in the unidirectional lay-up consisted of longitudinal cracks which initiated at the shearmore » stress concentration points on the hole periphery. Reversed cyclic loading caused continued crack growth at maximum stresses below the tension-tension fatigue limit. The cross-ply lay-up appeared insensitive to the hole, while critical damage in the unidirectional lay-up was dependent on the shear stress concentrations at the hole.... Ceramic matrix composite, Tension-compression fatigue, Notched specimen.« less

14 CFR 25.367 - Unsymmetrical loads due to engine failure.

Code of Federal Regulations, 2013 CFR

2013-01-01

... the engine compressor from the turbine or from loss of the turbine blades are considered to be... § 25.367 Unsymmetrical loads due to engine failure. (a) The airplane must be designed for the unsymmetrical loads resulting from the failure of the critical engine. Turbopropeller airplanes must be designed...

14 CFR 25.367 - Unsymmetrical loads due to engine failure.

Code of Federal Regulations, 2010 CFR

2010-01-01

... the engine compressor from the turbine or from loss of the turbine blades are considered to be... § 25.367 Unsymmetrical loads due to engine failure. (a) The airplane must be designed for the unsymmetrical loads resulting from the failure of the critical engine. Turbopropeller airplanes must be designed...

14 CFR 25.367 - Unsymmetrical loads due to engine failure.

Code of Federal Regulations, 2011 CFR

2011-01-01

... the engine compressor from the turbine or from loss of the turbine blades are considered to be... § 25.367 Unsymmetrical loads due to engine failure. (a) The airplane must be designed for the unsymmetrical loads resulting from the failure of the critical engine. Turbopropeller airplanes must be designed...

Evaluation of a metal fuselage frame selectively reinforced with filamentary composites for space shuttle application

NASA Technical Reports Server (NTRS)

Oken, S.; Skoumal, D. E.; Straayer, J. W.

1974-01-01

The development of metal structures reinforced with filamentary composites as a weight saving feature of the space shuttle components is discussed. A frame was selected for study that was representative of the type of construction used in the bulk frames of the orbiter vehicle. Theoretical and experimental investigations were conducted. Component tests were performed to evaluate the critical details used in the designs and to provide credibility to the weight saving results. A model frame was constructed of the reinforced metal material to provide a final evaluation of the construction under realistic load conditions.

Ergonomics and sitting at work.

PubMed

Corlett, E N

2009-01-01

Many factors influence the performance at the workplace. The immediate interface between the user and the equipment is, perhaps, the most important. Hence, the arrangements of the seat and work point are critical.Factors which cause discomfort and injury to seated workers are described and, from the behaviour of the spine under load, a better seat design is presented. Its use by a wide variety of workers makes it necessary to introduce increased adjustability, beyond that normally part of conventional seat design. The application of the new design in two cases in industry, as well as its introduction in schools, is briefly covered.

Instruction set commutivity

NASA Technical Reports Server (NTRS)

Windley, P.

1992-01-01

We present a state property called congruence and show how it can be used to demonstrate commutivity of instructions in a modern load-store architecture. Our analysis is particularly important in pipelined microprocessors where instructions are frequently reordered to avoid costly delays in execution caused by hazards. Our work has significant implications to safety and security critical applications since reordering can easily change the meaning and an instruction sequence and current techniques are largely ad hoc. Our work is done in a mechanical theorem prover and results in a set of trustworthy rules for instruction reordering. The mechanization makes it practical to analyze the entire instruction set.

Advancing Lie Detection by Inducing Cognitive Load on Liars: A Review of Relevant Theories and Techniques Guided by Lessons from Polygraph-Based Approaches

PubMed Central

Walczyk, Jeffrey J.; Igou, Frank P.; Dixon, Alexa P.; Tcholakian, Talar

2013-01-01

This article critically reviews techniques and theories relevant to the emerging field of “lie detection by inducing cognitive load selectively on liars.” To help these techniques benefit from past mistakes, we start with a summary of the polygraph-based Controlled Question Technique (CQT) and the major criticisms of it made by the National Research Council (2003), including that it not based on a validated theory and administration procedures have not been standardized. Lessons from the more successful Guilty Knowledge Test are also considered. The critical review that follows starts with the presentation of models and theories offering insights for cognitive lie detection that can undergird theoretically load-inducing approaches. This is followed by evaluation of specific research-based, load-inducing proposals, especially for their susceptibility to rehearsal and other countermeasures. To help organize these proposals and suggest new direction for innovation and refinement, a theoretical taxonomy is presented based on the type of cognitive load induced in examinees (intrinsic or extraneous) and how open-ended the responses to test items are. Finally, four recommendations are proffered that can help researchers and practitioners to avert the corresponding mistakes with the CQT and yield new, valid cognitive lie detection technologies. PMID:23378840

Assessment of the transport routes of oversized and excessive loads in relation to the passage through roundabout

NASA Astrophysics Data System (ADS)

Petru, Jan; Dolezel, Jiri; Krivda, Vladislav

2017-09-01

In the past the excessive and oversized loads were realized on selected routes on roads that were adapted to ensure smooth passage of transport. Over the years, keeping the passages was abandoned and currently there are no earmarked routes which would be adapted for such type of transportation. The routes of excessive and oversized loads are currently planned to ensure passage of the vehicle through the critical points on the roads. Critical points are level and fly-over crossings of roads, bridges, toll gates, traffic signs and electrical and other lines. The article deals with the probability assessment of selected critical points of the route of the excessive load on the roads of 1st class, in relation to ensuring the passage through the roundabout. The bases for assessing the passage of the vehicle with excessive load through a roundabout are long-term results of video analyses of monitoring the movement of transports on similar intersections and determination of the theoretical probability model of vehicle movement at selected junctions. On the basis of a virtual simulation of the vehicle movement at crossroads and using MonteCarlo simulation method vehicles’ paths are analysed and the probability of exit of the vehicle outside the crossroad in given junctions is quantified.

Critical Loads of Acid Deposition for Wilderness Lakes in the Sierra Nevada (California) Estimated by the Steady-State Water Chemistry Model

Treesearch

Glenn D. Shaw; Ricardo Cisneros; Donald Schweizer; James O. Sickman; Mark E. Fenn

2014-01-01

Major ion chemistry (2000-2009) from 208 lakes (342 sample dates and 600 samples) in class I and II wilderness areas of the Sierra Nevada was used in the Steady-State Water Chemistry (SSWC) model to estimate critical loads for acid deposition and investigate the current vulnerability of high elevation lakes to acid deposition. The majority of the lakes were dilute (...

Critical loads and their exceedances at intensive forest monitoring sites in Europe.

PubMed

Lorenz, Martin; Nagel, Hans-Dieter; Granke, Oliver; Kraft, Philipp

2008-10-01

Intensive forest monitoring by means of harmonised methods has been conducted in Europe for more than a decade. Risks of atmospheric nitrogen and sulphur deposition are assessed by means of calculations of critical loads and their exceedances. In the present study throughfall and bulk deposition of nitrate (N-NO(3)), ammonium (N-NH(4)) and sulphate (S-SO(4)) show marked spatial patterns and temporal trends. In the period of observation (1999-2004), sulphate deposition on intensive monitoring plots decreased by about one quarter. This is in line with the reduction of S deposition by 70% since 1981 in Europe as a result of successful air pollution control politics under the Convention on Long-range Transboundary Air Pollution (CLRTAP). However, sulphate and especially nitrate and ammonium deposition were found to still exceed critical loads at many forest sites, indicating a continued need for further implementation of air pollution abatement strategies.

Acid deposition and assessment of its critical load for the environmental health of waterbodies in a subtropical watershed, China

NASA Astrophysics Data System (ADS)

Jia, Junjie; Gao, Yang

2017-12-01

Atmospheric acidic deposition in subtropical watersheds poses an environmental risk of causing acidification of aquatic ecosystems. In this study, we evaluated the frequency of acid deposition in a subtropical forest ecosystem and the associated critical loads of acidity for a sensitive aquatic ecosystem. We found that out of 132 rainfall events, 33(25%) were acidic rainfall occurrences. Estimated wet acid deposition (2282.78 eq·ha-1·yr-1), consistent with SO42- and NH4+ deposition, was high in spring and summer and low in autumn and winter. Waterbodies surrounded by mixed wood and citrus orchard experience severe acidification, mostly from S deposition because acidic deposition exceeds the corresponding critical loads of acidity. Modifications that take acid rain deposition into consideration are needed for land-use and agricultural management strategies to improve the environmental health of waterbodies in subtropical watersheds.

14 CFR 29.471 - General.

Code of Federal Regulations, 2010 CFR

2010-01-01

... equilibrium. For limit ground loads— (1) The limit ground loads obtained in the landing conditions in this... equilibrium with linear and angular inertia loads in a rational or conservative manner. (b) Critical centers...

Rocketdyne PSAM: In-house enhancement/application

NASA Technical Reports Server (NTRS)

Newell, J. F.; Rajagopal, K. R.; Ohara, K.

1991-01-01

The development was initiated of the Probabilistic Design Analysis (PDA) Process for rocket engines. This will enable engineers a quantitative assessment of calculated reliability during the design process. The PDA will help choose better designs, make them more robust, and help decide on critical tests to help demonstrate key reliability issues to aid in improving the confidence of the engine capabilities. Rockedyne's involvement with the Composite Loads Spectra (CLS) and Probabilistic Structural Analysis Methodology (PSAM) contracts started this effort and are key elements in the on-going developments. Internal development efforts and hardware applications complement and extend the CLS and PSAM efforts. The completion of the CLS option work and the follow-on PSAM developments will also be integral parts of this methodology. A brief summary of these efforts is presented.

Investigation of fatigue strength of tool steels in sheet-bulk metal forming

NASA Astrophysics Data System (ADS)

Pilz, F.; Gröbel, D.; Merklein, M.

2018-05-01

To encounter trends regarding an efficient production of complex functional components in forming technology, the process class of sheet-bulk metal forming (SBMF) can be applied. SBMF is characterized by the application of bulk forming operations on sheet metal, often in combination with sheet forming operations [1]. The combination of these conventional process classes leads to locally varying load conditions. The resulting load conditions cause high tool loads, which lead to a reduced tool life, and an uncontrolled material flow. Several studies have shown that locally modified tool surfaces, so-called tailored surfaces, have the potential to control the material flow and thus to increase the die filling of functional elements [2]. A combination of these modified tool surfaces and high tool loads in SBMF is furthermore critical for the tool life and leads to fatigue. Tool fatigue is hardly predictable and due to a lack of data [3], a challenge in tool design. Thus, it is necessary to provide such data for tool steels used in SBMF. The aim of this study is the investigation of the influence of tailored surfaces on the fatigue strength of the powder metallurgical tool steel ASP2023 (1.3344, AISI M3:2), which is typically used in cold forging applications, with a hardness 60 HRC ± 1 HRC. To conduct this investigation, the rotating bending test is chosen. As tailored surfaces, a DLC-coating and a surface manufactured by a high-feed-milling process are chosen. As reference a polished surface which is typical for cold forging tools is used. Before the rotating bending test, the surface integrity is characterized by measuring topography and residual stresses. After testing, the determined values of the surface integrity are correlated with the reached fracture load cycle to derive functional relations. Based on the gained results the investigated tailored surfaces are evaluated regarding their feasibility to modify tool surfaces within SBMF.

14 CFR 23.307 - Proof of structure.

Code of Federal Regulations, 2011 CFR

2011-01-01

.... Dynamic tests, including structural flight tests, are acceptable if the design load conditions have been... critical load condition. Structural analysis may be used only if the structure conforms to those for which...

Validation of lumbar spine loading from a musculoskeletal model including the lower limbs and lumbar spine.

PubMed

Actis, Jason A; Honegger, Jasmin D; Gates, Deanna H; Petrella, Anthony J; Nolasco, Luis A; Silverman, Anne K

2018-02-08

Low back mechanics are important to quantify to study injury, pain and disability. As in vivo forces are difficult to measure directly, modeling approaches are commonly used to estimate these forces. Validation of model estimates is critical to gain confidence in modeling results across populations of interest, such as people with lower-limb amputation. Motion capture, ground reaction force and electromyographic data were collected from ten participants without an amputation (five male/five female) and five participants with a unilateral transtibial amputation (four male/one female) during trunk-pelvis range of motion trials in flexion/extension, lateral bending and axial rotation. A musculoskeletal model with a detailed lumbar spine and the legs including 294 muscles was used to predict L4-L5 loading and muscle activations using static optimization. Model estimates of L4-L5 intervertebral joint loading were compared to measured intradiscal pressures from the literature and muscle activations were compared to electromyographic signals. Model loading estimates were only significantly different from experimental measurements during trunk extension for males without an amputation and for people with an amputation, which may suggest a greater portion of L4-L5 axial load transfer through the facet joints, as facet loads are not captured by intradiscal pressure transducers. Pressure estimates between the model and previous work were not significantly different for flexion, lateral bending or axial rotation. Timing of model-estimated muscle activations compared well with electromyographic activity of the lumbar paraspinals and upper erector spinae. Validated estimates of low back loading can increase the applicability of musculoskeletal models to clinical diagnosis and treatment. Copyright © 2017 Elsevier Ltd. All rights reserved.

The Damaging Effects of Earthquake Excitation on Concrete Cooling Towers

NASA Astrophysics Data System (ADS)

Abedi-Nik, Farhad; Sabouri-Ghomi, Saeid

2008-07-01

Reinforced concrete cooling towers of hyperbolic shell configuration find widespread application in utilities engaged in the production of electric power. In design of critical civil infrastructure of this type, it is imperative to consider all the possible loading conditions that the cooling tower may experience, an important loading condition in many countries is that of the earthquake excitation, whose influence on the integrity and stability of cooling towers is profound. Previous researches have shown that the columns supporting a cooling tower are sensitive to earthquake forces, as they are heavily loaded elements that do not possess high ductility, and understanding the behavior of columns under earthquake excitation is vital in structural design because they provide the load path for the self weight of the tower shell. This paper presents the results of a finite element investigation of a representative "dry" cooling tower, using realistic horizontal and vertical acceleration data obtained from the recent and widely-reported Tabas, Naghan and Bam earthquakes in Iran. The results of both linear and nonlinear analyses are reported in the paper, the locations of plastic hinges within the supporting columns are identified and the ramifications of the plastic hinges on the stability of the cooling tower are assessed. It is concluded that for the (typical) cooling tower configuration analyzed, the columns that are instrumental in providing a load path are influenced greatly by earthquake loading, and for the earthquake data used in this study the representative cooling tower would be rendered unstable and would collapse under the earthquake forces considered.

The Damaging Effects of Earthquake Excitation on Concrete Cooling Towers

DOE Office of Scientific and Technical Information (OSTI.GOV)

Abedi-Nik, Farhad; Sabouri-Ghomi, Saeid

2008-07-08

Reinforced concrete cooling towers of hyperbolic shell configuration find widespread application in utilities engaged in the production of electric power. In design of critical civil infrastructure of this type, it is imperative to consider all the possible loading conditions that the cooling tower may experience, an important loading condition in many countries is that of the earthquake excitation, whose influence on the integrity and stability of cooling towers is profound. Previous researches have shown that the columns supporting a cooling tower are sensitive to earthquake forces, as they are heavily loaded elements that do not possess high ductility, and understandingmore » the behavior of columns under earthquake excitation is vital in structural design because they provide the load path for the self weight of the tower shell. This paper presents the results of a finite element investigation of a representative 'dry' cooling tower, using realistic horizontal and vertical acceleration data obtained from the recent and widely-reported Tabas, Naghan and Bam earthquakes in Iran. The results of both linear and nonlinear analyses are reported in the paper, the locations of plastic hinges within the supporting columns are identified and the ramifications of the plastic hinges on the stability of the cooling tower are assessed. It is concluded that for the (typical) cooling tower configuration analyzed, the columns that are instrumental in providing a load path are influenced greatly by earthquake loading, and for the earthquake data used in this study the representative cooling tower would be rendered unstable and would collapse under the earthquake forces considered.« less

Colistin Population Pharmacokinetics after Application of a Loading Dose of 9 MU Colistin Methanesulfonate in Critically Ill Patients

PubMed Central

Friberg, Lena E.; Pontikis, Konstantinos; Ioannidis, Konstantinos; Tsagkari, Vasiliki; Galani, Lamprini; Kostakou, Eirini; Baziaka, Fotini; Paskalis, Charalambos; Koutsoukou, Antonia; Giamarellou, Helen

2015-01-01

Colistin has been revived, in the era of extensively drug-resistant (XDR) Gram-negative infections, as the last-resort treatment in critically ill patients. Recent studies focusing on the optimal dosing strategy of colistin have demonstrated the necessity of a loading dose at treatment initiation (D. Plachouras, M. Karvanen, L. E. Friberg, E. Papadomichelakis, A. Antoniadou, I. Tsangaris, I. Karaiskos, G. Poulakou, F. Kontopidou, A. Armaganidis, O. Cars, and H. Giamarellou, Antimicrob Agents Chemother 53:3430–3436, 2009, http://dx.doi.org/10.1128/AAC.01361-08; A. F. Mohamed, I. Karaiskos, D. Plachouras, M. Karvanen, K. Pontikis, B. Jansson, E. Papadomichelakis, A. Antoniadou, H. Giamarellou, A. Armaganidis, O. Cars, and L. E. Friberg, Antimicrob Agents Chemother 56:4241– 4249, 2012, http://dx.doi.org/10.1128/AAC.06426-11; S. M. Garonzik, J. Li, V. Thamlikitkul, D. L. Paterson, S. Shoham, J. Jacob, F. P. Silveira, A. Forrest, and R. L. Nation, Antimicrob Agents Chemother 55:3284–3294, 2011, http://dx.doi.org/10.1128/AAC.01733-10). In 19 critically ill patients with suspected or microbiologically documented infections caused by XDR Gram-negative strains, a loading dose of 9 MU colistin methanesulfonate (CMS) (∼270 mg colistin base activity) was administered with a maintenance dose of 4.5 MU every 12 h, commenced after 24 h. Patients on renal replacement were excluded. CMS infusion was given over 30 min or 1 h. Repeated blood sampling was performed after the loading dose and after the 5th or 6th dose. Colistin concentrations and measured CMS, determined after hydrolization to colistin and including the partially sulfomethylated derivatives, were determined with a liquid chromatography-tandem mass spectrometry assay. Population pharmacokinetic analysis was conducted in NONMEM with the new data combined with data from previous studies. Measured colistimethate concentrations were described by 4 compartments for distribution and removal of sulfomethyl groups, while colistin disposition followed a 1-compartment model. The average observed maximum colistin A plus B concentration was 2.65 mg/liter after the loading dose (maximum time was 8 h). A significantly higher availability of the measured A and B forms of colistimethate and colistin explained the higher-than-expected concentrations in the present study compared to those in previous studies. Creatinine clearance was a time-varying covariate of colistimethate clearance. The incidence of acute renal injury was 20%. PMID:26369974

Colistin Population Pharmacokinetics after Application of a Loading Dose of 9 MU Colistin Methanesulfonate in Critically Ill Patients.

PubMed

Karaiskos, Ilias; Friberg, Lena E; Pontikis, Konstantinos; Ioannidis, Konstantinos; Tsagkari, Vasiliki; Galani, Lamprini; Kostakou, Eirini; Baziaka, Fotini; Paskalis, Charalambos; Koutsoukou, Antonia; Giamarellou, Helen

2015-12-01

Colistin has been revived, in the era of extensively drug-resistant (XDR) Gram-negative infections, as the last-resort treatment in critically ill patients. Recent studies focusing on the optimal dosing strategy of colistin have demonstrated the necessity of a loading dose at treatment initiation (D. Plachouras, M. Karvanen, L. E. Friberg, E. Papadomichelakis, A. Antoniadou, I. Tsangaris, I. Karaiskos, G. Poulakou, F. Kontopidou, A. Armaganidis, O. Cars, and H. Giamarellou, Antimicrob Agents Chemother 53:3430-3436, 2009, http://dx.doi.org/10.1128/AAC.01361-08; A. F. Mohamed, I. Karaiskos, D. Plachouras, M. Karvanen, K. Pontikis, B. Jansson, E. Papadomichelakis, A. Antoniadou, H. Giamarellou, A. Armaganidis, O. Cars, and L. E. Friberg, Antimicrob Agents Chemother 56:4241- 4249, 2012, http://dx.doi.org/10.1128/AAC.06426-11; S. M. Garonzik, J. Li, V. Thamlikitkul, D. L. Paterson, S. Shoham, J. Jacob, F. P. Silveira, A. Forrest, and R. L. Nation, Antimicrob Agents Chemother 55:3284-3294, 2011, http://dx.doi.org/10.1128/AAC.01733-10). In 19 critically ill patients with suspected or microbiologically documented infections caused by XDR Gram-negative strains, a loading dose of 9 MU colistin methanesulfonate (CMS) (∼ 270 mg colistin base activity) was administered with a maintenance dose of 4.5 MU every 12 h, commenced after 24 h. Patients on renal replacement were excluded. CMS infusion was given over 30 min or 1 h. Repeated blood sampling was performed after the loading dose and after the 5th or 6th dose. Colistin concentrations and measured CMS, determined after hydrolization to colistin and including the partially sulfomethylated derivatives, were determined with a liquid chromatography-tandem mass spectrometry assay. Population pharmacokinetic analysis was conducted in NONMEM with the new data combined with data from previous studies. Measured colistimethate concentrations were described by 4 compartments for distribution and removal of sulfomethyl groups, while colistin disposition followed a 1-compartment model. The average observed maximum colistin A plus B concentration was 2.65 mg/liter after the loading dose (maximum time was 8 h). A significantly higher availability of the measured A and B forms of colistimethate and colistin explained the higher-than-expected concentrations in the present study compared to those in previous studies. Creatinine clearance was a time-varying covariate of colistimethate clearance. The incidence of acute renal injury was 20%. Copyright © 2015, American Society for Microbiology. All Rights Reserved.

Using Critical Loads to Look at Improvements in Acidic Surface Water Conditions since the 1990 Amendments to the Clear Air Act: Case Study Adirondack, NY

NASA Astrophysics Data System (ADS)

Lynch, J. A.; Kolian, M. J.; Haeuber, R.

2008-12-01

Acid deposition has affected hundreds of lakes and thousands of miles of headwater streams in the Adirondack region of New York State. The diversity of life in these acidic waters has been greatly reduced. The poor buffering capacity of the thin, acidic soils in the Adirondack Mountains makes the lakes and ponds particularly susceptible to acidification. Since the mid-1990's, lakes in the Adirondack region are finally showing signs of recovery. The good news is that emissions of sulfur dioxide and nitrogen oxides have been reduced and as a result acidic deposition of sulfate and nitrate has decreased in surface waters approximately 26 and 13%, respectively. This has led to improvement in the acid neutralizing capacity (ANC) of these water bodies. Although improvement in water quality is a good sign, it does not tell us if a particular lake or a group of lakes have recovered from decades of acidic deposition. However, the critical loads approach does allow for evaluation of whether a water body has reached recovery for acidic deposition. Critical loads and exceedances for lake surface water and acidity were calculated for 187 lakes in the Adirondack region. The Steady-State Water Chemistry (SSWC) model was used to calculate the critical load, relying on water chemistry data from the TIME/LTM network. An ANC threshold of 50 μeq/L was selected for this case study. Exceedances were calculated from deposition for the period before implementation of the Acid Rain program (ARP) (1989-1991) and for the period of 2004-2006 to judge improvements as a result of the ARP. On average, the critical load for lakes in the Adirondack region is 164 meq/m2/yr, while it is 48 meq/m2/yr for the most sensitive lakes (i.e. ANC less than 100 μeq/L). For the period from 2004 to 2006, 65% of the lakes within the TIME/LTM network continued to receive levels of acid deposition that exceeded the lake's critical load down from 72% of lakes before implementation of the Acid Rain Program. Despite improvement in water quality that has occurred over the past decades in the Adirondack region additional reduction in acidic deposition is needed in order for greater recovery of these sensitive aquatic systems.

Testing Measurement Invariance Using MIMIC: Likelihood Ratio Test with a Critical Value Adjustment

ERIC Educational Resources Information Center

Kim, Eun Sook; Yoon, Myeongsun; Lee, Taehun

2012-01-01

Multiple-indicators multiple-causes (MIMIC) modeling is often used to test a latent group mean difference while assuming the equivalence of factor loadings and intercepts over groups. However, this study demonstrated that MIMIC was insensitive to the presence of factor loading noninvariance, which implies that factor loading invariance should be…

Dynamic analysis of elastic rubber tired car wheel breaking under variable normal load

NASA Astrophysics Data System (ADS)

Fedotov, A. I.; Zedgenizov, V. G.; Ovchinnikova, N. I.

2017-10-01

The purpose of the paper is to analyze the dynamics of the braking of the wheel under normal load variations. The paper uses a mathematical simulation method according to which the calculation model of an object as a mechanical system is associated with a dynamically equivalent schematic structure of the automatic control. Transfer function tool analyzing structural and technical characteristics of an object as well as force disturbances were used. It was proved that the analysis of dynamic characteristics of the wheel subjected to external force disturbances has to take into account amplitude and phase-frequency characteristics. Normal load variations impact car wheel braking subjected to disturbances. The closer slip to the critical point is, the higher the impact is. In the super-critical area, load variations cause fast wheel blocking.

Inverse analysis of aerodynamic loads from strain information using structural models and neural networks

NASA Astrophysics Data System (ADS)

Wada, Daichi; Sugimoto, Yohei

2017-04-01

Aerodynamic loads on aircraft wings are one of the key parameters to be monitored for reliable and effective aircraft operations and management. Flight data of the aerodynamic loads would be used onboard to control the aircraft and accumulated data would be used for the condition-based maintenance and the feedback for the fatigue and critical load modeling. The effective sensing techniques such as fiber optic distributed sensing have been developed and demonstrated promising capability of monitoring structural responses, i.e., strains on the surface of the aircraft wings. By using the developed techniques, load identification methods for structural health monitoring are expected to be established. The typical inverse analysis for load identification using strains calculates the loads in a discrete form of concentrated forces, however, the distributed form of the loads is essential for the accurate and reliable estimation of the critical stress at structural parts. In this study, we demonstrate an inverse analysis to identify the distributed loads from measured strain information. The introduced inverse analysis technique calculates aerodynamic loads not in a discrete but in a distributed manner based on a finite element model. In order to verify the technique through numerical simulations, we apply static aerodynamic loads on a flat panel model, and conduct the inverse identification of the load distributions. We take two approaches to build the inverse system between loads and strains. The first one uses structural models and the second one uses neural networks. We compare the performance of the two approaches, and discuss the effect of the amount of the strain sensing information.

Experimental results from the VENUS-F critical reference state for the GUINEVERE accelerator driven system project

DOE Office of Scientific and Technical Information (OSTI.GOV)

Uyttenhove, W.; Baeten, P.; Ban, G.

The GUINEVERE (Generation of Uninterrupted Intense Neutron pulses at the lead Venus Reactor) project was launched in 2006 within the framework of FP6 EUROTRANS in order to validate on-line reactivity monitoring and subcriticality level determination in Accelerator Driven Systems. Therefore the VENUS reactor at SCK.CEN in Mol (Belgium) was modified towards a fast core (VENUS-F) and coupled to the GENEPI-3C accelerator built by CNRS The accelerator can operate in both continuous and pulsed mode. The VENUS-F core is loaded with enriched Uranium and reflected with solid lead. A well-chosen critical reference state is indispensable for the validation of the on-linemore » subcriticality monitoring methodology. Moreover a benchmarking tool is required for nuclear data research and code validation. In this paper the design and the importance of the critical reference state for the GUINEVERE project are motivated. The results of the first experimental phase on the critical core are presented. The control rods worth is determined by the rod drop technique and the application of the Modified Source Multiplication (MSM) method allows the determination of the worth of the safety rods. The results are implemented in the VENUS-F core certificate for full exploitation of the critical core. (authors)« less

Experimental results from the VENUS-F critical reference state for the GUINEVERE accelerator driven system project

DOE Office of Scientific and Technical Information (OSTI.GOV)

Uyttenhove, W.; Baeten, P.; Kochetkov, A.

The GUINEVERE (Generation of Uninterrupted Intense Neutron pulses at the lead Venus Reactor) project was launched in 2006 within the framework of FP6 EUROTRANS in order to validate online reactivity monitoring and subcriticality level determination in accelerator driven systems (ADS). Therefore, the VENUS reactor at SCK.CEN in Mol, Belgium, was modified towards a fast core (VENUS-F) and coupled to the GENEPI-3C accelerator built by CNRS. The accelerator can operate in both continuous and pulsed mode. The VENUS-F core is loaded with enriched Uranium and reflected with solid lead. A well-chosen critical reference state is indispensable for the validation of themore » online subcriticality monitoring methodology. Moreover, a benchmarking tool is required for nuclear data research and code validation. In this paper, the design and the importance of the critical reference state for the GUINEVERE project are motivated. The results of the first experimental phase on the critical core are presented. The control rods worth is determined by the positive period method and the application of the Modified Source Multiplication (MSM) method allows the determination of the worth of the safety rods. The results are implemented in the VENUS-F core certificate for full exploitation of the critical core. (authors)« less

Fabrication and characterization of joined silicon carbide cylindrical components for nuclear applications

NASA Astrophysics Data System (ADS)

Khalifa, H. E.; Deck, C. P.; Gutierrez, O.; Jacobsen, G. M.; Back, C. A.

2015-02-01

The use of silicon carbide (SiC) composites as structural materials in nuclear applications necessitates the development of a viable joining method. One critical application for nuclear-grade joining is the sealing of fuel within a cylindrical cladding. This paper demonstrates cylindrical joint feasibility using a low activation nuclear-grade joint material comprised entirely of β-SiC. While many papers have considered joining material, this paper takes into consideration the joint geometry and component form factor, as well as the material performance. Work focused specifically on characterizing the strength and permeability performance of joints between cylindrical SiC-SiC composites and monolithic SiC endplugs. The effects of environment and neutron irradiation were not evaluated in this study. Joint test specimens of different geometries were evaluated in their as-fabricated state, as well as after being subjected to thermal cycling and partial mechanical loading. A butted scarf geometry supplied the best combination of high strength and low permeability. A leak rate performance of 2 × 10-9 mbar l s-1 was maintained after thermal cycling and partial mechanical loading and sustained applied force of 3.4 kN, or an apparent strength of 77 MPa. This work shows that a cylindrical SiC-SiC composite tube sealed with a butted scarf endplug provides out-of-pile strength and permeability performance that meets light water reactor design requirements.

Complex systems analysis of series of blackouts: cascading failure, critical points, and self-organization.

PubMed

Dobson, Ian; Carreras, Benjamin A; Lynch, Vickie E; Newman, David E

2007-06-01

We give an overview of a complex systems approach to large blackouts of electric power transmission systems caused by cascading failure. Instead of looking at the details of particular blackouts, we study the statistics and dynamics of series of blackouts with approximate global models. Blackout data from several countries suggest that the frequency of large blackouts is governed by a power law. The power law makes the risk of large blackouts consequential and is consistent with the power system being a complex system designed and operated near a critical point. Power system overall loading or stress relative to operating limits is a key factor affecting the risk of cascading failure. Power system blackout models and abstract models of cascading failure show critical points with power law behavior as load is increased. To explain why the power system is operated near these critical points and inspired by concepts from self-organized criticality, we suggest that power system operating margins evolve slowly to near a critical point and confirm this idea using a power system model. The slow evolution of the power system is driven by a steady increase in electric loading, economic pressures to maximize the use of the grid, and the engineering responses to blackouts that upgrade the system. Mitigation of blackout risk should account for dynamical effects in complex self-organized critical systems. For example, some methods of suppressing small blackouts could ultimately increase the risk of large blackouts.

Optimal Multi-Type Sensor Placement for Structural Identification by Static-Load Testing

PubMed Central

Papadopoulou, Maria; Vernay, Didier; Smith, Ian F. C.

2017-01-01

Assessing ageing infrastructure is a critical challenge for civil engineers due to the difficulty in the estimation and integration of uncertainties in structural models. Field measurements are increasingly used to improve knowledge of the real behavior of a structure; this activity is called structural identification. Error-domain model falsification (EDMF) is an easy-to-use model-based structural-identification methodology which robustly accommodates systematic uncertainties originating from sources such as boundary conditions, numerical modelling and model fidelity, as well as aleatory uncertainties from sources such as measurement error and material parameter-value estimations. In most practical applications of structural identification, sensors are placed using engineering judgment and experience. However, since sensor placement is fundamental to the success of structural identification, a more rational and systematic method is justified. This study presents a measurement system design methodology to identify the best sensor locations and sensor types using information from static-load tests. More specifically, three static-load tests were studied for the sensor system design using three types of sensors for a performance evaluation of a full-scale bridge in Singapore. Several sensor placement strategies are compared using joint entropy as an information-gain metric. A modified version of the hierarchical algorithm for sensor placement is proposed to take into account mutual information between load tests. It is shown that a carefully-configured measurement strategy that includes multiple sensor types and several load tests maximizes information gain. PMID:29240684

Monitoring of fatigue damage in composite lap-joints using guided waves and FBG sensors

NASA Astrophysics Data System (ADS)

Karpenko, Oleksii; Khomenko, Anton; Koricho, Ermias; Haq, Mahmoodul; Udpa, Lalita

2016-02-01

Adhesive bonding is being increasingly employed in many applications as it offers possibility of light-weighting and efficient multi-material joining along with reduction in time and cost of manufacturing. However, failure initiation and progression in critical components like joints, specifically in fatigue loading is not well understood, which necessitates reliable NDE and SHM techniques to ensure structural integrity. In this work, concurrent guided wave (GW) and fiber Bragg grating (FBG) sensor measurements were used to monitor fatigue damage in adhesively bonded composite lap-joints. In the present set-up, one FBG sensor was strategically embedded in the adhesive bond-line of a lap-joint, while two other FBGs were bonded on the surface of the adherends. Full spectral responses of FBG sensors were collected and compared at specific intervals of fatigue loading. In parallel, guided waves were actuated and sensed using PZT wafers mounted on the composite adherends. Experimental results demonstrated that time-of-flight (ToF) of the fundamental modes transmitted through the bond-line and spectral response of FBG sensors were sensitive to fatigue loading and damage. Combination of guided wave and FBG measurements provided the desired redundancy and synergy in the data to evaluate the degradation in bond-line properties. Measurements taken in the presence of continuously applied load replicated the in-situ/service conditions. The approach shows promise in understanding the behavior of bonded joints subjected to complex loading.

Inverse load calculation procedure for offshore wind turbines and application to a 5-MW wind turbine support structure: Inverse load calculation procedure for offshore wind turbines

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pahn, T.; Rolfes, R.; Jonkman, J.

A significant number of wind turbines installed today have reached their designed service life of 20 years, and the number will rise continuously. Most of these turbines promise a more economical performance if they operate for more than 20 years. To assess a continued operation, we have to analyze the load-bearing capacity of the support structure with respect to site-specific conditions. Such an analysis requires the comparison of the loads used for the design of the support structure with the actual loads experienced. This publication presents the application of a so-called inverse load calculation to a 5-MW wind turbine supportmore » structure. The inverse load calculation determines external loads derived from a mechanical description of the support structure and from measured structural responses. Using numerical simulations with the software fast, we investigated the influence of wind-turbine-specific effects such as the wind turbine control or the dynamic interaction between the loads and the support structure to the presented inverse load calculation procedure. fast is used to study the inverse calculation of simultaneously acting wind and wave loads, which has not been carried out until now. Furthermore, the application of the inverse load calculation procedure to a real 5-MW wind turbine support structure is demonstrated. In terms of this practical application, setting up the mechanical system for the support structure using measurement data is discussed. The paper presents results for defined load cases and assesses the accuracy of the inversely derived dynamic loads for both the simulations and the practical application.« less

Measurement of fracture toughness by nanoindentation methods: Recent advances and future challenges

DOE PAGES

Sebastiani, Marco; Johanns, K. E.; Herbert, Erik G.; ...

2015-04-30

In this study, we describe recent advances and developments for the measurement of fracture toughness at small scales by the use of nanoindentation-based methods including techniques based on micro-cantilever beam bending and micro-pillar splitting. A critical comparison of the techniques is made by testing a selected group of bulk and thin film materials. For pillar splitting, cohesive zone finite element simulations are used to validate a simple relationship between the critical load at failure, the pillar radius, and the fracture toughness for a range of material properties and coating/substrate combinations. The minimum pillar diameter required for nucleation and growth ofmore » a crack during indentation is also estimated. An analysis of pillar splitting for a film on a dissimilar substrate material shows that the critical load for splitting is relatively insensitive to the substrate compliance for a large range of material properties. Experimental results from a selected group of materials show good agreement between single cantilever and pillar splitting methods, while a discrepancy of ~25% is found between the pillar splitting technique and double-cantilever testing. It is concluded that both the micro-cantilever and pillar splitting techniques are valuable methods for micro-scale assessment of fracture toughness of brittle ceramics, provided the underlying assumptions can be validated. Although the pillar splitting method has some advantages because of the simplicity of sample preparation and testing, it is not applicable to most metals because their higher toughness prevents splitting, and in this case, micro-cantilever bend testing is preferred.« less

Vegetation community change points suggest that critical loads of nutrient nitrogen may be too high

NASA Astrophysics Data System (ADS)

Wilkins, Kayla; Aherne, Julian; Bleasdale, Andy

2016-12-01

It is widely accepted that elevated nitrogen deposition can have detrimental effects on semi-natural ecosystems, including changes to plant diversity. Empirical critical loads of nutrient nitrogen have been recommended to protect many sensitive European habitats from significant harmful effects. In this study, we used Threshold Indicator Taxa Analysis (TITAN) to investigate shifts in vegetation communities along an atmospheric nitrogen deposition gradient for twenty-two semi-natural habitat types (as described under Annex I of the European Union Habitats Directive) in Ireland. Significant changes in vegetation community, i.e., change points, were determined for twelve habitats, with seven habitats showing a decrease in the number of positive indicator species. Community-level change points indicated a decrease in species abundance along a nitrogen deposition gradient ranging from 3.9 to 15.3 kg N ha-1 yr-1, which were significantly lower than recommended critical loads (Wilcoxon signed-rank test; V = 6, p < 0.05). These results suggest that lower critical loads of empirical nutrient nitrogen deposition may be required to protect many European habitats. Changes to vegetation communities may mean a loss of sensitive indicator species and potentially rare species in these habitats, highlighting how emission reductions policies set under the National Emissions Ceilings Directive may be directly linked to meeting the goal set out under the European Union's Biodiversity Strategy of "halting the loss of biodiversity" across Europe by 2020.

Nitrogen deposition and exceedance of critical loads for nutrient nitrogen in Irish grasslands.

PubMed

Henry, Jason; Aherne, Julian

2014-02-01

High resolution nitrogen (N) deposition maps were developed to assess the exceedance of empirical critical loads of nutrient N for grasslands in Ireland. Nitrogen emissions have remained relatively constant during the past 20 yrs and are projected to remain constant under current legislation. Total N deposition (estimated as wet nitrate [NO3(-)] and ammonium [NH4(+)] plus dry NO× and NH3) ranged from 2 to 22 kg Nha(-1)yr(-1) (mean=12 kg Nha(-1)yr(-1)) to grasslands. Empirical critical loads for nutrient N were set at 15 kg Nha(-1)yr(-1) for both acid and calcareous grasslands; exceedance was observed for ~35% (~2,311 km(2)) of mapped acid grasslands. In contrast, only ~9% of calcareous grasslands (~35 km(2)) received N deposition in excess of the critical load. Reduced N deposition (primarily dry NH3) represented the dominant form to grasslands (range 55-90%) owing to significant emissions associated with livestock (primarily cattle). The extent of exceedance in acid grasslands suggests that N deposition to this habitat type may lead to adverse impacts such as a decline in plant species diversity and soil acidification. Further, given that elevated N deposition was dominated by NH3 associated with agricultural emissions rather than long-range transboundary sources, future improvements in air quality need to be driven by national policies. © 2013.

Load cell verification of the uprated high pressure oxygen turbopump for the Space Shuttle Main Engine

NASA Technical Reports Server (NTRS)

Beatty, R. F.; Hine, M. J.

1986-01-01

The high pressure turbomachinery of the Space Shuttle Main Engine has the highest power-to-weight ratio of any operational machine known. Subsynchronous rotor whirl of the high pressure oxygen turbopump occurred in development testing at full-power level (109 percent thrust). The means by which the turbopump was successfully uprated is presented herein. The subsynchronous motion was determined to be driven by impeller destabilizing forces in combination with low net damping and bearing degradation. The degradation resulted from ball wear due primarily to an excessive loading condition of operating too near the lightly damped rotor second critical speed while under a large static load and, secondarily, from reverse bearing loading or loss of internal clearance and coolant during simulated flight conditions. The rotor response was reduced by stiffening the shaft and supports, optimizing the stiffness and damping of annular seals, and increasing the bearing deadband. The uprated oxygen turbopump configuration was verified by converting the pump and bearing support into a load cell for the purpose of systematically quantifying the load reduction benefits relative to baseline turbopumps. The damped second critical speed margin and the load sharing have been substantially improved which has resulted in reduced bearing loads for improved service life of the machine at full-power level.

Active buckling control of a beam-column with circular cross-section using piezo-elastic supports and integral LQR control

NASA Astrophysics Data System (ADS)

Schaeffner, Maximilian; Götz, Benedict; Platz, Roland

2016-06-01

Buckling of slender beam-columns subject to axial compressive loads represents a critical design constraint for light-weight structures. Active buckling control provides a possibility to stabilize slender beam-columns by active lateral forces or bending moments. In this paper, the potential of active buckling control of an axially loaded beam-column with circular solid cross-section by piezo-elastic supports is investigated experimentally. In the piezo-elastic supports, lateral forces of piezoelectric stack actuators are transformed into bending moments acting in arbitrary directions at the beam-column ends. A mathematical model of the axially loaded beam-column is derived to design an integral linear quadratic regulator (LQR) that stabilizes the system. The effectiveness of the stabilization concept is investigated in an experimental test setup and compared with the uncontrolled system. With the proposed active buckling control it is possible to stabilize the beam-column in arbitrary lateral direction for axial loads up to the theoretical critical buckling load of the system.

Insights into MHC class I peptide loading from the structure of the tapasin/ERp57 heterodimer

PubMed Central

Dong, Gang; Wearsch, Pamela A.; Peaper, David R.; Cresswell, Peter; Reinisch, Karin M.

2009-01-01

SUMMARY Tapasin is a glycoprotein critical for loading Major Histocompatibility Complex (MHC) class I molecules with high affinity peptides. It functions within the multimeric peptide-loading complex (PLC) as a disulfide-linked, stable heterodimer with the thiol oxidoreductase ERp57, and this covalent interaction is required to support optimal PLC activity. Here we present the 2.6 Å resolution structure of the tapasin/ERp57 core of the PLC. The structure reveals the basis for the stable dimerization of tapasin and ERp57 and provides the first example of a protein disulfide isomerase family member interacting with a substrate. Mutational analysis identified a conserved surface on tapasin that interacts with MHC class I molecules and is critical for the peptide loading and editing function of the tapasin-ERp57 heterodimer. By combining the tapasin/ERp57 structure with those of other defined PLC components we present a molecular model that illuminates the processes involved in MHC class I peptide loading. PMID:19119025

An Interactive User Interface for Drug Labeling to Improve Readability and Decision-Making

PubMed Central

Abedtash, Hamed; Duke, Jon D.

2015-01-01

FDA-approved prescribing information (also known as product labeling or labels) contain critical safety information for health care professionals. Drug labels have often been criticized, however, for being overly complex, difficult to read, and rife with overwarning, leading to high cognitive load. In this project, we aimed to improve the usability of drug labels by increasing the ‘signal-to-noise ratio’ and providing meaningful information to care providers based on patient-specific comorbidities and concomitant medications. In the current paper, we describe the design process and resulting web application, known as myDrugLabel. Using the Structured Product Label documents as a base, we describe the process of label personalization, readability improvements, and integration of diverse evidence sources, including the medical literature from PubMed, pharmacovigilance reports from FDA adverse event reporting system (FAERS), and social media signals directly into the label. PMID:26958158

An Interactive User Interface for Drug Labeling to Improve Readability and Decision-Making.

PubMed

Abedtash, Hamed; Duke, Jon D

FDA-approved prescribing information (also known as product labeling or labels) contain critical safety information for health care professionals. Drug labels have often been criticized, however, for being overly complex, difficult to read, and rife with overwarning, leading to high cognitive load. In this project, we aimed to improve the usability of drug labels by increasing the 'signal-to-noise ratio' and providing meaningful information to care providers based on patient-specific comorbidities and concomitant medications. In the current paper, we describe the design process and resulting web application, known as myDrugLabel. Using the Structured Product Label documents as a base, we describe the process of label personalization, readability improvements, and integration of diverse evidence sources, including the medical literature from PubMed, pharmacovigilance reports from FDA adverse event reporting system (FAERS), and social media signals directly into the label.

Efficient, Decentralized Detection of Qualitative Spatial Events in a Dynamic Scalar Field

PubMed Central

Jeong, Myeong-Hun; Duckham, Matt

2015-01-01

This paper describes an efficient, decentralized algorithm to monitor qualitative spatial events in a dynamic scalar field. The events of interest involve changes to the critical points (i.e., peak, pits and passes) and edges of the surface network derived from the field. Four fundamental types of event (appearance, disappearance, movement and switch) are defined. Our algorithm is designed to rely purely on qualitative information about the neighborhoods of nodes in the sensor network and does not require information about nodes’ coordinate positions. Experimental investigations confirm that our algorithm is efficient, with O(n) overall communication complexity (where n is the number of nodes in the sensor network), an even load balance and low operational latency. The accuracy of event detection is comparable to established centralized algorithms for the identification of critical points of a surface network. Our algorithm is relevant to a broad range of environmental monitoring applications of sensor networks. PMID:26343672

Efficient, Decentralized Detection of Qualitative Spatial Events in a Dynamic Scalar Field.

PubMed

Jeong, Myeong-Hun; Duckham, Matt

2015-08-28

This paper describes an efficient, decentralized algorithm to monitor qualitative spatial events in a dynamic scalar field. The events of interest involve changes to the critical points (i.e., peak, pits and passes) and edges of the surface network derived from the field. Four fundamental types of event (appearance, disappearance, movement and switch) are defined. Our algorithm is designed to rely purely on qualitative information about the neighborhoods of nodes in the sensor network and does not require information about nodes' coordinate positions. Experimental investigations confirm that our algorithm is efficient, with O(n) overall communication complexity (where n is the number of nodes in the sensor network), an even load balance and low operational latency. The accuracy of event detection is comparable to established centralized algorithms for the identification of critical points of a surface network. Our algorithm is relevant to a broad range of environmental monitoring applications of sensor networks.

Zero expansion glass ceramic ZERODUR® roadmap for advanced lithography

NASA Astrophysics Data System (ADS)

Westerhoff, Thomas; Jedamzik, Ralf; Hartmann, Peter

2013-04-01

The zero expansion glass ceramic ZERODUR® is a well-established material in microlithography in critical components as wafer- and reticle-stages, mirrors and frames in the stepper positioning and alignment system. The very low coefficient of thermal expansion (CTE) and its extremely high CTE homogeneity are key properties to achieve the tight overlay requirements of advanced lithography processes. SCHOTT is continuously improving critical material properties of ZERODUR® essential for microlithography applications according to a roadmap driven by the ever tighter material specifications broken down from the customer roadmaps. This paper will present the SCHOTT Roadmap for ZERODUR® material property development. In the recent years SCHOTT established a physical model based on structural relaxation to describe the coefficient of thermal expansion's temperature dependence. The model is successfully applied for the new expansion grade ZERODUR® TAILORED introduced to the market in 2012. ZERODUR® TAILORED delivers the lowest thermal expansion of ZERODUR® products at microlithography tool application temperature allowing for higher thermal stability for tighter overlay control in IC production. Data will be reported demonstrating the unique CTE homogeneity of ZERODUR® and its very high reproducibility, a necessary precondition for serial production for microlithography equipment components. New data on the bending strength of ZERODUR® proves its capability to withstand much higher mechanical loads than previously reported. Utilizing a three parameter Weibull distribution it is possible to derive minimum strength values for a given ZERODUR® surface treatment. Consequently the statistical uncertainties of the earlier approach based on a two parameter Weibull distribution have been eliminated. Mechanical fatigue due to stress corrosion was included in a straightforward way. The derived formulae allows calculating life time of ZERODUR® components for a given stress load or the allowable maximum stress for a minimum required life time.

Application of a newly built semi-submersible vessel for transportation of a tension leg platform

NASA Astrophysics Data System (ADS)

Zhang, Dagang; Sun, Weiying; Fan, Zhixia

2012-09-01

Transportation of tension leg platform (TLP) structures for a long distance has always been associated with the use of a heavy semi-transport vessel. The requirements of this type of vessel are always special, and their availability is limited. To prepare for the future development of South China Sea deepwater projects, the China Offshore Oil Engineering Corporation has recently built a heavy lift transport vessel-Hai Yang Shi You 278. This semi-submersible vessel has a displacement capacity of 50k DWT, and a breath of 42 meters. Understanding the vessel's applicability and preparing it for use in future deepwater projects are becoming imminent needs. This paper reviews the current critical issues associated with TLP transportation and performs detailed analysis of the designed TLP during load-out and transportation. The newly built COOEC transportation vessel HYSY 278 was applied to dry transport of the TLP structure from the COOEC fabrication yard in Qingdao to an oil field in South China Sea. The entire process included the load-out of the TLP structure from the landsite of the fabrication yard, the offloading and float-on of the platform from the vessel, the dry transport of the TLP over a long distance, and the final offloading of the platform. Both hydrodynamic and structure analysis were performed to evaluate the behavior of the transport vessel and TLP structure. Special attention was paid to critical areas associated with the use of this new vessel, along with any potential limitations. The results demonstrate that HYSY 278 can effectively be used for transporting the structure with proper arrangement and well-prepared operation. The procedure and details were presented on the basis of the study results. Special attention was also given to discussion on future use based on the results from the analysis.

A Review of Australian and New Zealand Investigations on Aeronautical Fatigue During the Period April 2003 to March 2005

DTIC Science & Technology

2005-05-01

through the Application of Loading (FINAL) (B. Dixon, S. Barter and L. Molent, DSTO...possible that of an aircraft in flight. This required a high degree of load fidelity and a high rate of test load application . This was accomplished by...Identification through the Application of Loading (FINAL) (B. Dixon, S. Barter and L. Molent, DSTO) The teardown and inspection of aircraft, which have

14 CFR 23.367 - Unsymmetrical loads due to engine failure.

Code of Federal Regulations, 2010 CFR

2010-01-01

... the engine compressor from the turbine or from loss of the turbine blades are considered to be... be designed for the unsymmetrical loads resulting from the failure of the critical engine including...

14 CFR 23.367 - Unsymmetrical loads due to engine failure.

Code of Federal Regulations, 2013 CFR

2013-01-01

... the engine compressor from the turbine or from loss of the turbine blades are considered to be... be designed for the unsymmetrical loads resulting from the failure of the critical engine including...

A single network adaptive critic (SNAC) architecture for optimal control synthesis for a class of nonlinear systems.

PubMed

Padhi, Radhakant; Unnikrishnan, Nishant; Wang, Xiaohua; Balakrishnan, S N

2006-12-01

Even though dynamic programming offers an optimal control solution in a state feedback form, the method is overwhelmed by computational and storage requirements. Approximate dynamic programming implemented with an Adaptive Critic (AC) neural network structure has evolved as a powerful alternative technique that obviates the need for excessive computations and storage requirements in solving optimal control problems. In this paper, an improvement to the AC architecture, called the "Single Network Adaptive Critic (SNAC)" is presented. This approach is applicable to a wide class of nonlinear systems where the optimal control (stationary) equation can be explicitly expressed in terms of the state and costate variables. The selection of this terminology is guided by the fact that it eliminates the use of one neural network (namely the action network) that is part of a typical dual network AC setup. As a consequence, the SNAC architecture offers three potential advantages: a simpler architecture, lesser computational load and elimination of the approximation error associated with the eliminated network. In order to demonstrate these benefits and the control synthesis technique using SNAC, two problems have been solved with the AC and SNAC approaches and their computational performances are compared. One of these problems is a real-life Micro-Electro-Mechanical-system (MEMS) problem, which demonstrates that the SNAC technique is applicable to complex engineering systems.

Physiological constraints on deceleration during the aerocapture of manned vehicles

NASA Technical Reports Server (NTRS)

Lyne, J. E.

1992-01-01

The peak deceleration load allowed for aerobraking of manned vehicles is a critical parameter in planning future excursions to Mars. However, considerable variation exists in the limits used by various investigators. The goal of this study was to determine the most appropriate level for this limit. Methods: Since previous U.S. space flights have been limited to 84 days duration, Soviet flight results were examined. Published details of Soviet entry trajectories were not available. However, personal communication with Soviet cosmonauts suggested that peak entry loads of 5-6 G had been encountered upon return from 8 months in orbit. Soyuz entry capsule's characteristics were established and the capsule's entry trajectory was numerically calculated. The results confirm a peak load of 5 to 6 G. Results: Although the Soviet flights were of shorter duration than expected Mars missions, evidence exists that the deceleration experience is applicable. G tolerance has been shown to stabilize after 1 to 3 months in space if adequate countermeasures are used. The calculated Soyuz deceleration histories are graphically compared with those expected for Mars aerobraking. Conclusions: Previous spaceflight experience supports the use of a 5 G limit for the aerocapture of a manned vehicle at Mars.

miktoarm polymer: controlled synthesis, characterization, and application as anticancer drug carrier

NASA Astrophysics Data System (ADS)

Lin, Wenjing; Nie, Shuyu; Xiong, Di; Guo, Xindong; Wang, Jufang; Zhang, Lijuan

2014-05-01

Amphiphilic A2(BC)2 miktoarm star polymers [poly(ɛ-caprolactone)]2-[poly(2-(diethylamino)ethyl methacrylate)- b- poly(poly(ethylene glycol) methyl ether methacrylate)]2 [(PCL)2(PDEA- b-PPEGMA)2] were developed by a combination of ring opening polymerization (ROP) and continuous activators regenerated by electron transfer atom transfer radical polymerization (ARGET ATRP). The critical micelle concentration (CMC) values were extremely low (0.0024 to 0.0043 mg/mL), depending on the architecture of the polymers. The self-assembled empty and doxorubicin (DOX)-loaded micelles were spherical in morphologies, and the average sizes were about 63 and 110 nm. The release of DOX at pH 5.0 was much faster than that at pH 6.5 and pH 7.4. Moreover, DOX-loaded micelles could effectively inhibit the growth of cancer cells HepG2 with IC50 of 2.0 μg/mL. Intracellular uptake demonstrated that DOX was delivered into the cells effectively after the cells were incubated with DOX-loaded micelles. Therefore, the pH-sensitive (PCL)2(PDEA- b-PPEGMA)2 micelles could be a prospective candidate as anticancer drug carrier for hydrophobic drugs with sustained release behavior.

Oxygen Delivery from Hyperbarically Loaded Microtanks Extends Cell Viability in Anoxic Environments

PubMed Central

Cook, Colin A.; Hahn, Kathryn C.; Morrissette-McAlmon, Justin B.F.; Grayson, Warren L.

2016-01-01

Oxygen diffusion limitations within nascent tissue engineered (TE) grafts lead to the development of hypoxic regions, cell death, and graft failure. Previous efforts have been made to deliver oxygen within TE scaffolds, including peroxide-doping, perfluorocarbons, and hyperbaric oxygen therapy, to mitigate these effects and help maintain post transplantation cell viability, but these have suffered from significant drawbacks. Here we present a novel approach utilizing polymeric hollow-core microspheres that can be hyperbarically loaded with oxygen and subsequently provide prolonged oxygen delivery. These oxygen carriers are termed, microtanks. With an interest in orthopedic applications, we combined microtanks within polycaprolactone to form solid phase constructs with oxygen delivery capabilities. The mathematical laws governing oxygen delivery from microtank-loaded constructs are developed along with empirical validation. Constructs achieved periods of oxygen delivery out to 6 days, which was shown to prolong the survival of human adipose derived stem cells (hASCs) and human umbilical vein endothelial cells (HUVECs) as well as to enhance their cellular morphology under anoxic conditions. The results of this study suggest the microtank approach may be a feasible means of maintaining cell viability in TE scaffolds during the critical period of vascularization in vivo. PMID:25818444

Changes in speckle patterns induced by load application onto an optical fiber and its possible application for sensing purpose

NASA Astrophysics Data System (ADS)

Hasegawa, Makoto; Okumura, Jyun-ya; Hyuga, Akio

2015-08-01

Speckle patterns to be observed in an output light spot from an optical fiber are known to be changed due to external disturbances applied onto the optical fiber. In order to investigate possibilities of utilizing such changes in speckle patterns for sensing application, a certain load was applied onto a jacket-covered communication-grade multi-mode glass optical fiber through which laser beams emitted from a laser diode were propagating, and observed changes in speckle patterns in the output light spot from the optical fiber were investigated both as image data via a CCD camera and as an output voltage from a photovoltaic panel irradiated with the output light spot. The load was applied via a load application mechanism in which several ridges were provided onto opposite flat plates and a certain number of weights were placed there so that corrugated bending of the optical fiber was intentionally induced via load application due to the ridges. The obtained results showed that the number of speckles in the observed pattern in the output light spot as well as the output voltage from the photovoltaic panel irradiated with the output light spot showed decreases upon load application with relatively satisfactory repeatability. When the load was reduced, i.e., the weights were removed, the number of speckles then showed recovery. These results indicate there is a certain possibility of utilizing changes in speckle patterns for sensing of load application onto the optical fiber.

Can the watershed non-point phosphorus pollution be interpreted by critical soil properties? A new insight of different soil P states.

PubMed

Lin, Chen; Ma, Ronghua; Xiong, Junfeng

2018-07-01

The physicochemical properties of surface soil play a key role in the fate of watershed non-point source pollution. Special emphasis is needed to identify soil properties that are sensitive to both particulate P (PP) pollution and dissolved P (DP) pollution, which is essential for watershed environmental management. The Chaohu Lake basin, a typical eutrophic lake in China, was selected as the study site. The spatial features of the Non-point Source (NPS) PP loads and DP loads were calculated simultaneously based on the integration of sediment delivery distributed model (SEDD) and pollution loads (PLOAD) model. Then several critical physicochemical soil properties, especially various soil P compositions, were innovatively introduced to determine the response of the critical soil properties to NPS P pollution. The findings can be summarized: i) the mean PP load value of the different sub-basins was 5.87 kg, and PP pollution is regarded to be the primary NPS P pollution state, while the DP loads increased rapidly under the rapid urbanization process. ii) iron-bound phosphorus (Fe-P) and aluminum-bound phosphorus (Al-P) are the main components of available P and showed the most sensitive responses to NPS PP pollution, and the correlation coefficients were approximately 0.9. Otherwise, the residual phosphorus (Res-P) was selected as a sensitive soil P state that was significantly negatively correlated with the DP loads. iii) The DP and PP concentrations were represented differently when they were correlated with various soil properties, and the clay proportion was strongly negatively related to the PP loads. Meanwhile, there is a non-linear relationship between the DP loads and the critical soil properties, such as Fe and Total Nitrogen (TN) concentrations. Specifically, a strong inhibitory effect of TN concentration on the DP load was apparent in the Nanfei river (NF) and Paihe (PH) river basins where the R 2 reached 0.67, which contrasts with the relatively poor relationship within the other five basins. In addition, the degree of correlation between the Fe and DP loads severely degraded in the basins that were mostly covered by construction land or those that underwent a rapid urbanization process. The findings indicate that land use/cover change (LUCC), especially the distribution of agricultural land and construction land, as well as the soil background information (TN, Fe and Soil organic matters, etc.) can be considered as factors that influence NPS P pollution. Copyright © 2018 Elsevier B.V. All rights reserved.

18 CFR 16.10 - Information to be provided by an applicant for new license: Filing requirements.

Code of Federal Regulations, 2013 CFR

2013-04-01

... applicant's operating and load characteristics; and (C) The communities served or to be served, including... the contributions from the applicant's generation, purchases, and load modification measures (such as...; and (C) If load management measures are not viewed as resources, the effects of such measures on the...

18 CFR 16.10 - Information to be provided by an applicant for new license: Filing requirements.

Code of Federal Regulations, 2010 CFR

2010-04-01

... applicant's operating and load characteristics; and (C) The communities served or to be served, including... the contributions from the applicant's generation, purchases, and load modification measures (such as...; and (C) If load management measures are not viewed as resources, the effects of such measures on the...

18 CFR 16.10 - Information to be provided by an applicant for new license: Filing requirements.

Code of Federal Regulations, 2014 CFR

2014-04-01

... applicant's operating and load characteristics; and (C) The communities served or to be served, including... the contributions from the applicant's generation, purchases, and load modification measures (such as...; and (C) If load management measures are not viewed as resources, the effects of such measures on the...

18 CFR 16.10 - Information to be provided by an applicant for new license: Filing requirements.

Code of Federal Regulations, 2011 CFR

2011-04-01

... applicant's operating and load characteristics; and (C) The communities served or to be served, including... the contributions from the applicant's generation, purchases, and load modification measures (such as...; and (C) If load management measures are not viewed as resources, the effects of such measures on the...

18 CFR 16.10 - Information to be provided by an applicant for new license: Filing requirements.

Code of Federal Regulations, 2012 CFR

2012-04-01

... applicant's operating and load characteristics; and (C) The communities served or to be served, including... the contributions from the applicant's generation, purchases, and load modification measures (such as...; and (C) If load management measures are not viewed as resources, the effects of such measures on the...

A proposed procedure for expressing the behavior of a full engine cycle by identifying its critical load timings

NASA Astrophysics Data System (ADS)

Marius Andrei, Mihalache; Gheorghe, Nagit; Gavril, Musca; Vasile, Merticaru, Jr.; Marius Ionut, Ripanu

2016-11-01

In the present study the authors propose a new algorithm for identifying the right loads that act upon a functional connecting rod during a full engine cycle. The loads are then divided into three categories depending on the results they produce, as static, semi-dynamic and dynamic ones Because an engine cycle extends up to 720°, the authors aim to identify a method of substitution of values that produce the same effect as a previous value of a considered angle did. In other words, the proposed method aims to pin point the critical values that produce an effect different as the one seen before during a full engine cycle. Only those values will then be considered as valid loads that act upon the connecting rod inside FEA analyses. This technique has been applied to each of the three categories mentioned above and did produced different critical values for each one of them. The whole study relies on a theoretical mechanical project which was developed in order to identify the right values that correspond to each degree of the entire engine cycle of a Daewoo Tico automobile.

Relating fuel loads to overstorey structure and composition in a fire-excluded Sierra Nevada mixed conifer forest

Treesearch

Jamie M. Lydersen; Brandon M. Collins; Eric E. Knapp; Gary B. Roller; Scott Stephens

2015-01-01

Although knowledge of surface fuel loads is critical for evaluating potential fire behaviour and effects, their inherent variability makes these difficult to quantify. Several studies relate fuel loads to vegetation type, topography and spectral imaging, but little work has been done examining relationships between forest overstorey variables and surface fuel...

Critical and subcritical damage monitoring of bonded composite repairs using innovative non-destructive techniques

NASA Astrophysics Data System (ADS)

Grammatikos, S. A.; Kordatos, E. Z.; Aggelis, D. G.; Matikas, T. E.; Paipetis, A. S.

2012-04-01

Infrared Thermography (IrT) has been shown to be capable of detecting and monitoring service induced damage of repair composite structures. Full-field imaging, along with portability are the primary benefits of the thermographic technique. On-line lock-in thermography has been reported to successfully monitor damage propagation or/and stress concentration in composite coupons, as mechanical stresses in structures induce heat concentration phenomena around flaws. During mechanical fatigue, cyclic loading plays the role of the heating source and this allows for critical and subcritical damage identification and monitoring using thermography. The Electrical Potential Change Technique (EPCT) is a new method for damage identification and monitoring during loading. The measurement of electrical potential changes at specific points of Carbon Fiber Reinforced Polymers (CFRPs) under load are reported to enable the monitoring of strain or/and damage accumulation. Along with the aforementioned techniques Finally, Acoustic Emission (AE) method is well known to provide information about the location and type of damage. Damage accumulation due to cyclic loading imposes differentiation of certain parameters of AE like duration and energy. Within the scope of this study, infrared thermography is employed along with AE and EPCT methods in order to assess the integrity of bonded repair patches on composite substrates and to monitor critical and subcritical damage induced by the mechanical loading. The combined methodologies were effective in identifying damage initiation and propagation of bonded composite repairs.

Evaluation of cognitive load and emotional states during multidisciplinary critical care simulation sessions.

PubMed

Pawar, Swapnil; Jacques, Theresa; Deshpande, Kush; Pusapati, Raju; Meguerdichian, Michael J

2018-04-01

The simulation in critical care setting involves a heterogeneous group of participants with varied background and experience. Measuring the impacts of simulation on emotional state and cognitive load in this setting is not often performed. The feasibility of such measurement in the critical care setting needs further exploration. Medical and nursing staff with varying levels of experience from a tertiary intensive care unit participated in a standardised clinical simulation scenario. The emotional state of each participant was assessed before and after completion of the scenario using a validated eight-item scale containing bipolar oppositional descriptors of emotion. The cognitive load of each participant was assessed after the completion of the scenario using a validated subjective rating tool. A total of 103 medical and nursing staff participated in the study. The participants felt more relaxed (-0.28±1.15 vs 0.14±1, P<0.005; d=0.39), excited (0.25±0.89 vs 0.55±0.92, P<0.005, d=0.35) and alert (0.85±0.87 vs 1.28±0.73, P<0.00001, d=0.54) following simulation. There was no difference in the mean scores for the remaining five items. The mean cognitive load for all participants was 6.67±1.41. There was no significant difference in the cognitive loads among medical staff versus nursing staff (6.61±2.3 vs 6.62±1.7; P>0.05). A well-designed complex high fidelity critical care simulation scenario can be evaluated to identify the relative cognitive load of the participants' experience and their emotional state. The movement of learners emotionally from a more negative state to a positive state suggests that simulation can be an effective tool for improved knowledge transfer and offers more opportunity for dynamic thinking.

Does a critical rotator cuff tear stage exist?: a biomechanical study of rotator cuff tear progression in human cadaver shoulders.

PubMed

Oh, Joo Han; Jun, Bong Jae; McGarry, Michelle H; Lee, Thay Q

2011-11-16

It is unknown at which stage of rotator cuff tear the biomechanical environment is altered. The purpose of this study was to determine if a critical rotator cuff tear stage exists that alters glenohumeral joint biomechanics throughout the rotational range of shoulder motion, and to evaluate the biomechanical effect of parascapular muscle-loading. Eight cadaver shoulders were used with a custom testing system. Four progressive rotator cuff tear stages were investigated on the basis of footprint anatomy. Three muscle-loading conditions were examined: rotator cuff only; rotator cuff with deltoid muscle; and rotator cuff, deltoid, pectoralis major, and latissimus dorsi muscles. Testing was performed in the scapular plane with 0°, 30°, and 60° of shoulder abduction. The maximum internal and external rotations were measured with 3.4 Nm of torque. The position of the humeral head apex with respect to the glenoid was calculated with use of a MicroScribe 3DLX digitizing system throughout the rotational range of motion. The abduction capability was determined as the abduction angle achieved with increasing deltoid load. Tear of the entire supraspinatus tendon significantly increased maximum external rotation and significantly decreased abduction capability with higher deltoid loads (p < 0.05). Tear of the entire supraspinatus tendon and half of the infraspinatus tendon significantly shifted the humeral head apex posteriorly at the midrange of rotation and superiorly at maximum internal rotation (p < 0.05). Loading the pectoralis major and latissimus dorsi muscles decreased the amount of humeral head elevation due to deltoid loading. Tear of the entire supraspinatus tendon was the critical stage for increasing rotational range of shoulder motion and for decreased abduction capability. Further tear progression to the infraspinatus muscle was the critical stage for significant changes in humeral head kinematics. The pectoralis major and latissimus dorsi muscles played an important role in stabilizing the humeral head as the rotator cuff tear progressed.

URBAN/SUBURBAN WATERSHED CHARACTERIZATION

EPA Science Inventory

The ability to characterize the land surface and related pollutant source loadings is critical for reliable watershed modeling. Urban/suburban land uses are the most rapidly growing land use class, generating non-point source pollutant loadings likely to seriously impair streams...

Real-Time Unsteady Loads Measurements Using Hot-Film Sensors

NASA Technical Reports Server (NTRS)

Mangalam, Arun S.; Moes, Timothy R.

2004-01-01

Several flight-critical aerodynamic problems such as buffet, flutter, stall, and wing rock are strongly affected or caused by abrupt changes in unsteady aerodynamic loads and moments. Advanced sensing and flow diagnostic techniques have made possible simultaneous identification and tracking, in realtime, of the critical surface, viscosity-related aerodynamic phenomena under both steady and unsteady flight conditions. The wind tunnel study reported here correlates surface hot-film measurements of leading edge stagnation point and separation point, with unsteady aerodynamic loads on a NACA 0015 airfoil. Lift predicted from the correlation model matches lift obtained from pressure sensors for an airfoil undergoing harmonic pitchup and pitchdown motions. An analytical model was developed that demonstrates expected stall trends for pitchup and pitchdown motions. This report demonstrates an ability to obtain unsteady aerodynamic loads in real time, which could lead to advances in air vehicle safety, performance, ride-quality, control, and health management.

Real-Time Unsteady Loads Measurements Using Hot-Film Sensors

NASA Technical Reports Server (NTRS)

Mangalam, Arun S.; Moes, Timothy R.

2004-01-01

Several flight-critical aerodynamic problems such as buffet, flutter, stall, and wing rock are strongly affected or caused by abrupt changes in unsteady aerodynamic loads and moments. Advanced sensing and flow diagnostic techniques have made possible simultaneous identification and tracking, in real-time, of the critical surface, viscosity-related aerodynamic phenomena under both steady and unsteady flight conditions. The wind tunnel study reported here correlates surface hot-film measurements of leading edge stagnation point and separation point, with unsteady aerodynamic loads on a NACA 0015 airfoil. Lift predicted from the correlation model matches lift obtained from pressure sensors for an airfoil undergoing harmonic pitchup and pitchdown motions. An analytical model was developed that demonstrates expected stall trends for pitchup and pitchdown motions. This report demonstrates an ability to obtain unsteady aerodynamic loads in real-time, which could lead to advances in air vehicle safety, performance, ride-quality, control, and health management.

Aircraft stress sequence development: A complex engineering process made simple

NASA Technical Reports Server (NTRS)

Schrader, K. H.; Butts, D. G.; Sparks, W. A.

1994-01-01

Development of stress sequences for critical aircraft structure requires flight measured usage data, known aircraft loads, and established relationships between aircraft flight loads and structural stresses. Resulting cycle-by-cycle stress sequences can be directly usable for crack growth analysis and coupon spectra tests. Often, an expert in loads and spectra development manipulates the usage data into a typical sequence of representative flight conditions for which loads and stresses are calculated. For a fighter/trainer type aircraft, this effort is repeated many times for each of the fatigue critical locations (FCL) resulting in expenditure of numerous engineering hours. The Aircraft Stress Sequence Computer Program (ACSTRSEQ), developed by Southwest Research Institute under contract to San Antonio Air Logistics Center, presents a unique approach for making complex technical computations in a simple, easy to use method. The program is written in Microsoft Visual Basic for the Microsoft Windows environment.

The Pressure Distribution over the Wings and Tail Surfaces of a PW-9 Pursuit Airplane in Flight

NASA Technical Reports Server (NTRS)

Rhode, Richard

1931-01-01

This report presents the results of an investigation to determine (1) the magnitude and distribution of aerodynamic loads over the wings and tail surfaces of a pursuit-type airplane in the maneuvers likely to impose critical loads on the various subassemblies of the airplane structure. (2) To study the phenomenon of center of pressure movement and normal force coefficient variation in accelerated flight, and (3) to measure the normal accelerations at the center of gravity, wing-tip, and tail, in order to determine the nature of the inertia forces acting simultaneously with the critical aerodynamic loads. The results obtained throw light on a number of important questions involving structural design. Some of the more interesting results are discussed in some detail, but in general the report is for the purpose of making this collection of airplane-load data obtained in flight available to those interested in airplane structures.

Evaluation of Analysis Techniques for Fluted-Core Sandwich Cylinders

NASA Technical Reports Server (NTRS)

Lovejoy, Andrew E.; Schultz, Marc R.

2012-01-01

Buckling-critical launch-vehicle structures require structural concepts that have high bending stiffness and low mass. Fluted-core, also known as truss-core, sandwich construction is one such concept. In an effort to identify an analysis method appropriate for the preliminary design of fluted-core cylinders, the current paper presents and compares results from several analysis techniques applied to a specific composite fluted-core test article. The analysis techniques are evaluated in terms of their ease of use and for their appropriateness at certain stages throughout a design analysis cycle (DAC). Current analysis techniques that provide accurate determination of the global buckling load are not readily applicable early in the DAC, such as during preliminary design, because they are too costly to run. An analytical approach that neglects transverse-shear deformation is easily applied during preliminary design, but the lack of transverse-shear deformation results in global buckling load predictions that are significantly higher than those from more detailed analysis methods. The current state of the art is either too complex to be applied for preliminary design, or is incapable of the accuracy required to determine global buckling loads for fluted-core cylinders. Therefore, it is necessary to develop an analytical method for calculating global buckling loads of fluted-core cylinders that includes transverse-shear deformations, and that can be easily incorporated in preliminary design.

Buckling and weight optimization for non-coupled antisymmetric laminates

NASA Astrophysics Data System (ADS)

Bhatnagar, Aditi

This research work describes the application of genetic algorithms to weight minimization and buckling load maximization of the non-coupled antisymmetric composite laminated plates. Previous studies of composite tailoring were limited to symmetric and balanced laminates. With the availability of many methodologies for composite tailoring, genetic algorithm is preferably used because of its ability to handle discrete design variable and attain multiple near optimum design solutions. A comparative study is made between optimum symmetric-balanced laminate designs and optimum non-coupled antisymmetric laminate designs, both of which are subjected to biaxial in-plane compressive loads. With the implementation of various genetic algorithm operators such as selection, crossover and mutation, critical buckling load factors are obtained for the optimum stacking sequence for both types of laminates. The mechanical properties for non-coupled antisymmetric laminates is independent of all types of coupling effects such as bending-twisting coupling, bending-extension coupling, and shear-extension coupling, thus giving the laminate a non-coupling behavior. This is in contrast to that of symmetric-balanced laminates where finite bending-twisting coupling terms are present. Optimized laminate layups satisfying the constraints of balance, buckling and adjoining were obtained for two types of graphite epoxy rectangular composite laminated plates. The current research augments the laminate thickness minimization designs with both odd and even number of layers, and the optimum buckling load maximization designs by the introduction of non-coupled antisymmetric laminates.

Time-dependent constitutive modeling of drive belts—II. The effect of the shape of material retardation spectrum on the strain accumulation process

NASA Astrophysics Data System (ADS)

Zupančič, B.; Emri, I.

2009-11-01

This is the second paper in the series addressing the constitutive modeling of dynamically loaded elastomeric products such as power transmission belts. During the normal operation of such belts certain segments of the belt structure are loaded via tooth-like cyclical loading. When the time-dependent properties of the elastomeric material “match” the time-scale of the dynamic loading a strain accumulation (incrementation) process occurs. It was shown that the location of a critical rotation speed strongly depends on the distribution (shape) of the retardation spectrum, whereas the magnitude of the accumulated strain is governed by the strength of the corresponding spectrum lines. These interrelations are extremely non-linear. The strain accumulation process is most intensive at the beginning of the drive belt operation, and is less intensive for longer belts. The strain accumulation process is governed by the spectrum lines that are positioned within a certain region, which we call the Strain Accumulation Window (SAW). An SAW is always located to the right of the spectrum line, L i , at log ( ω λ i )=0, where ω is the operational angular velocity. The width of the SAW depends on the width of the material spectrum. Based on the following analysis a new designing criterion is proposed for use in engineering applications for selecting a proper material for general drive-belt operations.

Observations of Building Performance under Combined Wind and Surge Loading from Hurricane Harvey

NASA Astrophysics Data System (ADS)

Lombardo, F.; Roueche, D. B.; Krupar, R. J.; Smith, D. J.; Soto, M. G.

2017-12-01

Hurricane Harvey struck the Texas coastline on August 25, 2017, as a Category 4 hurricane - the first major hurricane to reach the US in twelve years. Wind gusts over 130 mph and storm surge as high as 12.5 ft caused widespread damage to buildings and critical infrastructure in coastal communities including Rockport, Fulton, Port Aransas and Aransas Pass. This study presents the methodology and preliminary observations of a coordinated response effort to document residential building performance under wind and storm surge loading. Over a twelve day survey period the study team assessed the performance of more than 1,000 individual, geo-located residential buildings. Assessments were logged via a smartphone application to facilitate rapid collection and collation of geotagged photographs, building attributes and structural details, and structural damage observations. Detailed assessments were also made of hazard intensity, specifically storm surge heights and both wind speed and direction indicators. Preliminary observations and findings will be presented, showing strong gradients in damage between inland and coastal regions of the affected areas that may be due in part to enhanced individual loading effects of wind and storm surge and potentially joint-hazard loading effects. Contributing factors to the many cases of disproportionate damage observed in close proximity will also be discussed. Ongoing efforts to relate building damage to near-surface hazard measurements (e.g., radar, anemometry) in close proximity will also be described.

Controlled Release of Antibiotics From Vitamin E-Loaded Silicone-Hydrogel Contact Lenses.

PubMed

Paradiso, Patrizia; Serro, Ana Paula; Saramago, Benilde; Colaço, Rogério; Chauhan, Anuj

2016-03-01

Symptoms of bacterial and fungal keratitis are typically treated through the frequent application of antibiotic and antifungal eye drops. The high frequency of half hourly or hourly eye drop administration required to treat these indications is tedious and could reduce compliance. Here, we combine in vitro experiments with a mathematical model to develop therapeutic soft contact lenses to cure keratitis by extended release of suitable drugs. We specifically focus on increasing the release duration of levofloxacin and chlorhexidine from 1-DAY ACUVUE(®) TrueEye™ and ACUVUE OASYS(®) contact lenses by incorporating vitamin E diffusion barriers. Results show that 20% of vitamin E loading in the contact lens increases the release duration of levofloxacin to 100 h and 50 h from 1-DAY ACUVUE(®) TrueEye™ and ACUVUE OASYS(®), respectively, which is a 3- and 6-fold increase, respectively, for the 2 lenses. For chlorhexidine, the increase is 2.5- and 10-fold, for the TrueEye™ and OASYS(®), respectively, to 130 h and 170 h. The mass of drug loaded in the lenses can be controlled to achieve a daily release comparable to the commonly prescribed eye drop therapy. The vitamin E-loaded lenses retain all critical properties for in vivo use. Copyright © 2016 American Pharmacists Association®. Published by Elsevier Inc. All rights reserved.

Semi-preparative asymmetrical flow field-flow fractionation: A closer look at channel dimensions and separation performance.

PubMed

Bria, Carmen R M; Skelly, Patrick W; Morse, James R; Schaak, Raymond E; Williams, S Kim Ratanathanawongs

2017-05-26

The design and performance of a semi-preparative asymmetrical flow field-flow fractionation (SP-AF4) channel are investigated with the objective of better understanding and exploiting the relationship between channel dimensions, sample loading, and resolution. Most size-based separations of nanometer and submicrometer particles are currently limited to analytical scale quantities (<100μg). However, there is a strong need to fractionate and collect larger quantities so that fundamental properties of the more narrowly dispersed fractions can be studied using additional characterization methods and for subsequent applications. In this work, dimensions of the spacer that defines the form of SP-AF4 channels are varied and their performances are assessed with respect to sample focusing position and loading. Separations are performed in aqueous and organic carrier fluids. A critical evaluation of channel dimensions showed that increasing the channel breadth is a practical and effective route to maintaining separation resolution while increasing sample loads to milligram quantities. Good size resolution (∼1.0) is achieved for separations of 10mg of 50 and 100nm silica nanoparticles suspended in water and up to 0.6mg of ∼10 to 35nm inorganic hybrid nanoparticles suspended in tetrahydrofuran. This work represents important advances in the understanding of SP-AF4 separations and extends sample loading capacities in both aqueous and organic solvents. Copyright © 2017 Elsevier B.V. All rights reserved.

Mechanisms of monoclonal antibody stabilization and release from silk biomaterials

PubMed Central

Guziewicz, Nicholas A.; Massetti, Andrew J.; Perez-Ramirez, Bernardo J.; Kaplan, David L.

2013-01-01

The availability of stabilization and sustained delivery systems for antibody therapeutics remains a major clinical challenge, despite the growing development of antibodies for a wide range of therapeutic applications due to their specificity and efficacy. A mechanistic understanding of protein-matrix interactions is critical for the development of such systems and is currently lacking as a mode to guide the field. We report mechanistic insight to address this need by using well-defined matrices based on silk gels, in combination with a monoclonal antibody. Variables including antibody loading, matrix density, charge interactions, hydrophobicity and water access were assessed to clarify mechanisms involved in the release of antibody from the biomaterial matrix. The results indicate that antibody release is primarily governed by hydrophobic interactions and hydration resistance, which are controlled by silk matrix chemistry, peptide domain distribution and protein density. Secondary ionic repulsions are also critical in antibody stabilization and release. Matrix modification by free methionine incorporation was found to be an effective strategy for mitigating encapsulation induced antibody oxidation. Additionally, these studies highlight a characterization approach to improve the understanding and development of other protein sustained delivery systems, with broad applicability to the rapidly developing monoclonal antibody field. PMID:23859659

Parylene coatings on stainless steel 316L surface for medical applications--mechanical and protective properties.

PubMed

Cieślik, Monika; Kot, Marcin; Reczyński, Witold; Engvall, Klas; Rakowski, Wiesław; Kotarba, Andrzej

2012-01-01

The mechanical and protective properties of parylene N and C coatings (2-20 μm) on stainless steel 316L implant materials were investigated. The coatings were characterized by scanning electron and confocal microscopes, microindentation and scratch tests, whereas their protective properties were evaluated in terms of quenching metal ion release from stainless steel to simulated body fluid (Hanks solution). The obtained results revealed that for parylene C coatings, the critical load for initial cracks is 3-5 times higher and the total metal ions release is reduced 3 times more efficiently compared to parylene N. It was thus concluded that parylene C exhibits superior mechanical and protective properties for application as a micrometer coating material for stainless steel implants. Copyright © 2011 Elsevier B.V. All rights reserved.

Consistent criticality and radiation studies of Swiss spent nuclear fuel: The CS2M approach.

PubMed

Rochman, D; Vasiliev, A; Ferroukhi, H; Pecchia, M

2018-06-15

In this paper, a new method is proposed to systematically calculate at the same time canister loading curves and radiation sources, based on the inventory information from an in-core fuel management system. As a demonstration, the isotopic contents of the assemblies come from a Swiss PWR, considering more than 6000 cases from 34 reactor cycles. The CS 2 M approach consists in combining four codes: CASMO and SIMULATE to extract the assembly characteristics (based on validated models), the SNF code for source emission and MCNP for criticality calculations for specific canister loadings. The considered cases cover enrichments from 1.9 to 5.0% for the UO 2 assemblies and 4.8% for the MOX, with assembly burnup values from 7 to 74 MWd/kgU. Because such a study is based on the individual fuel assembly history, it opens the possibility to optimize canister loadings from the point-of-view of criticality, decay heat and emission sources. Copyright © 2018 Elsevier B.V. All rights reserved.

Aging Aircraft Transparencies: AN Italian Air Force Fleet Case History

NASA Astrophysics Data System (ADS)

Caucci, D.; Aiello, L.; Bagnoli, F.; Bernabei, M.

2008-08-01

Aircraft acrylic transparencies are structural components that must withstand flight and ground loads. Crazing occurrence, known as Environmental Stress Cracking (ESC), causes their substitution during aircraft maintenance operations. This form of aging is mainly a physical phenomenon due to the interaction of transparencies base material with an active liquid and leads craze formation at lower stress that would be required in air. In this paper, an extensive phenomenon of network ESC occurred on transparencies of many aircrafts operating in the same fleet was investigated. Cover application while parking was found to be the critical aspect in crazing appearance, thus acting as physical shield for condensed water and heat transferring.

DNA Nanotechnology for Cancer Therapy

PubMed Central

Kumar, Vinit; Palazzolo, Stefano; Bayda, Samer; Corona, Giuseppe; Toffoli, Giuseppe; Rizzolio, Flavio

2016-01-01

DNA nanotechnology is an emerging and exciting field, and represents a forefront frontier for the biomedical field. The specificity of the interactions between complementary base pairs makes DNA an incredible building material for programmable and very versatile two- and three-dimensional nanostructures called DNA origami. Here, we analyze the DNA origami and DNA-based nanostructures as a drug delivery system. Besides their physical-chemical nature, we dissect the critical factors such as stability, loading capability, release and immunocompatibility, which mainly limit in vivo applications. Special attention was dedicated to highlighting the boundaries to be overcome to bring DNA nanostructures closer to the bedside of patients. PMID:27022418

A critical survey of wave propagation and impact in composite materials

NASA Technical Reports Server (NTRS)

Moon, F. C.

1973-01-01

A review of the field of stress waves in composite materials is presented covering the period up to December 1972. The major properties of waves in composites are discussed and a summary is made of the major experimental results in this field. Various theoretical models for analysis of wave propagation in laminated, fiber and particle reinforced composites are surveyed. The anisotropic, dispersive and dissipative properties of stress pulses and shock waves in such materials are reviewed. A review of the behavior of composites under impact loading is presented along with the application of wave propagation concepts to the determination of impact stresses in composite plates.

A dynamic modelling approach for estimating critical loads of nitrogen based on plant community changes under a changing climate.

PubMed

Belyazid, Salim; Kurz, Dani; Braun, Sabine; Sverdrup, Harald; Rihm, Beat; Hettelingh, Jean-Paul

2011-03-01

A dynamic model of forest ecosystems was used to investigate the effects of climate change, atmospheric deposition and harvest intensity on 48 forest sites in Sweden (n = 16) and Switzerland (n = 32). The model was used to investigate the feasibility of deriving critical loads for nitrogen (N) deposition based on changes in plant community composition. The simulations show that climate and atmospheric deposition have comparably important effects on N mobilization in the soil, as climate triggers the release of organically bound nitrogen stored in the soil during the elevated deposition period. Climate has the most important effect on plant community composition, underlining the fact that this cannot be ignored in future simulations of vegetation dynamics. Harvest intensity has comparatively little effect on the plant community in the long term, while it may be detrimental in the short term following cutting. This study shows: that critical loads of N deposition can be estimated using the plant community as an indicator; that future climatic changes must be taken into account; and that the definition of the reference deposition is critical for the outcome of this estimate. Copyright © 2010 Elsevier Ltd. All rights reserved.

Functional reconstruction of critical-sized load-bearing bone defects using a Sclerostin-targeting miR-210-3p-based construct to enhance osteogenic activity.

PubMed

Hu, Bin; Li, Yan; Wang, Mohan; Zhu, Youming; Zhou, Yong; Sui, Baiyan; Tan, Yu; Ning, Yujie; Wang, Jie; He, Jiacai; Yang, Chi; Zou, Duohong

2018-06-10

A considerable amount of research has focused on improving regenerative therapy strategies for repairing defects in load-bearing bones. The enhancement of tissue regeneration with microRNAs (miRNAs) is being developed because miRNAs can simultaneously regulate multiple signaling pathways in an endogenous manner. In this study, we developed a miR-210-based bone repair strategy. We identified a miRNA (miR-210-3p) that can simultaneously up-regulate the expression of multiple key osteogenic genes in vitro. This process resulted in enhanced bone formation in a subcutaneous mouse model with a miR-210-3p/poly-L-lactic acid (PLLA)/bone marrow-derived stem cell (BMSC) construct. Furthermore, we constructed a model of critical-sized load-bearing bone defects and implanted a miR-210-3p/β-tricalcium phosphate (β-TCP)/bone mesenchymal stem cell (BMSC) construct into the defect. We found that the load-bearing defect was almost fully repaired using the miR-210-3p construct. We also identified a new mechanism by which miR-210-3p regulates Sclerostin protein levels. This miRNA-based strategy may yield novel therapeutic methods for the treatment of regenerative defects in vital load-bearing bones by utilizing miRNA therapy for tissue engineering. The destroyed maxillofacial bone reconstruction is still a real challenge for maxillofacial surgeon, due to that functional bone reconstruction involved load-bearing. Base on the above problem, this paper developed a novel miR-210-3p/β-tricalcium phosphate (TCP)/bone marrow-derived stem cell (BMSC) construct (miR-210-3p/β-TCP/BMSCs), which lead to functional reconstruction of critical-size mandible bone defect. We found that the load-bearing defect was almost fully repaired using the miR-210-3p construct. In addition, we also found the mechanism of how the delivered microRNA activated the signaling pathways of endogenous stem cells, leading to the defect regeneration. This miRNA-based strategy can be used to regenerate defects in vital load-bearing bones, thus addressing a critical challenge in regenerative medicine by utilizing miRNA therapy for tissue engineering. Copyright © 2018 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.

Addendum to the User Manual for NASGRO Elastic-Plastic Fracture Mechanics Software Module

NASA Technical Reports Server (NTRS)

Gregg, M. Wayne (Technical Monitor); Chell, Graham; Gardner, Brian

2003-01-01

The elastic-plastic fracture mechanics modules in NASGRO have been enhanced by the addition of of the following: new J-integral solutions based on the reference stress method and finite element solutions; the extension of the critical crack and critical load modules for cracks with two degrees of freedom that tear and failure by ductile instability; the addition of a proof test analysis module that includes safe life analysis, calculates proof loads, and determines the flaw screening 1 capability for a given proof load; the addition of a tear-fatigue module for ductile materials that simultaneously tear and extend by fatigue; and a multiple cycle proof test module for estimating service reliability following a proof test.

Optical Coherence Elastography

NASA Astrophysics Data System (ADS)

Kennedy, Brendan F.; Kennedy, Kelsey M.; Oldenburg, Amy L.; Adie, Steven G.; Boppart, Stephen A.; Sampson, David D.

The mechanical properties of tissue are pivotal in its function and behavior, and are often modified by disease. From the nano- to the macro-scale, many tools have been developed to measure tissue mechanical properties, both to understand the contribution of mechanics in the origin of disease and to improve diagnosis. Optical coherence elastography is applicable to the intermediate scale, between that of cells and whole organs, which is critical in the progression of many diseases and not widely studied to date. In optical coherence elastography, a mechanical load is imparted to a tissue and the resulting deformation is measured using optical coherence tomography. The deformation is used to deduce a mechanical parameter, e.g., Young's modulus, which is mapped into an image, known as an elastogram. In this chapter, we review the development of optical coherence elastography and report on the latest developments. We provide a focus on the underlying principles and assumptions, techniques to measure deformation, loading mechanisms, imaging probes and modeling, including the inverse elasticity problem.

Implementation of DSC model and application for analysis of field pile tests under cyclic loading

NASA Astrophysics Data System (ADS)

Shao, Changming; Desai, Chandra S.

2000-05-01

The disturbed state concept (DSC) model, and a new and simplified procedure for unloading and reloading behavior are implemented in a nonlinear finite element procedure for dynamic analysis for coupled response of saturated porous materials. The DSC model is used to characterize the cyclic behavior of saturated clays and clay-steel interfaces. In the DSC, the relative intact (RI) behavior is characterized by using the hierarchical single surface (HISS) plasticity model; and the fully adjusted (FA) behavior is modeled by using the critical state concept. The DSC model is validated with respect to laboratory triaxial tests for clay and shear tests for clay-steel interfaces. The computer procedure is used to predict field behavior of an instrumented pile subjected to cyclic loading. The predictions provide very good correlation with the field data. They also yield improved results compared to those from a HISS model with anisotropic hardening, partly because the DSC model allows for degradation or softening and interface response.

Model-based reasoning for power system management using KATE and the SSM/PMAD

NASA Technical Reports Server (NTRS)

Morris, Robert A.; Gonzalez, Avelino J.; Carreira, Daniel J.; Mckenzie, F. D.; Gann, Brian

1993-01-01

The overall goal of this research effort has been the development of a software system which automates tasks related to monitoring and controlling electrical power distribution in spacecraft electrical power systems. The resulting software system is called the Intelligent Power Controller (IPC). The specific tasks performed by the IPC include continuous monitoring of the flow of power from a source to a set of loads, fast detection of anomalous behavior indicating a fault to one of the components of the distribution systems, generation of diagnosis (explanation) of anomalous behavior, isolation of faulty object from remainder of system, and maintenance of flow of power to critical loads and systems (e.g. life-support) despite fault conditions being present (recovery). The IPC system has evolved out of KATE (Knowledge-based Autonomous Test Engineer), developed at NASA-KSC. KATE consists of a set of software tools for developing and applying structure and behavior models to monitoring, diagnostic, and control applications.

Shrink-induced single-cell plastic microwell array.

PubMed

Lew, Valerie; Nguyen, Diep; Khine, Michelle

2011-12-01

The ability to interrogate and track single cells over time in a high-throughput format would provide critical information for fundamental biological understanding of processes and for various applications, including drug screening and toxicology. We have developed an ultrarapid and simple method to create single-cell wells of controllable diameter and depth with commodity shrink-wrap film and tape. Using a programmable CO(2) laser, we cut hole arrays into the tape. The tape then serves as a shadow mask to selectively etch wells into commodity shrink-wrap film by O(2) plasma. When the shrink-wrap film retracts upon briefly heating, high-aspect plastic microwell arrays with diameters down to 20 μm are readily achieved. We calibrated the loading procedure with fluorescent microbeads. Finally, we demonstrate the utility of the wells by loading fluorescently labeled single human embryonic stem cells into the wells. Copyright © 2011 Society for Laboratory Automation and Screening. Published by Elsevier Inc. All rights reserved.

The adsorption of tetracycline and vancomycin onto nanodiamond with controlled release.

PubMed

Giammarco, James; Mochalin, Vadym N; Haeckel, James; Gogotsi, Yury

2016-04-15

The unique properties and tailorable surface of detonation nanodiamonds have given rise to an abundance of potential biomedical applications. Very little is known about the details of adsorption/desorption equilibria of drugs on/from nanodiamonds with different purity, surface chemistry, and agglomeration state. The studies presented here delve into the details of adsorption and desorption of tetracycline (TET) and vancomycin (VAN) on nanodiamond, which are critically important for the rational design of the nanodiamond drug delivery systems. The nanodiamonds studied in these experiments were as-received (ND), purified and carboxyl terminated (ND-COOH), and aminated (ND-NH2). The monolayer capacities of the drugs loaded onto the nanodiamonds are reported herein using Langmuir and Freundlich isotherm models. The results from the desorption studies demonstrate that, by changing the pH environment of drug loaded nanodiamond using buffers of pH 4.09, 7.45, 8.02, and a phosphate buffered saline (PBS) solution, the drug release can effectively be triggered. Copyright © 2016 Elsevier Inc. All rights reserved.

Evaluation of dispersion strengthened nickel-base alloy heat shields for space shuttle application

NASA Technical Reports Server (NTRS)

Johnson, R., Jr.; Killpatrick, D. H.

1976-01-01

The results obtained in a program to evaluate dispersion-strengthened nickel-base alloys for use in a metallic radiative thermal protection system operating at surface temperatures to 1477 K for the space shuttle were presented. Vehicle environments having critical effects on the thermal protection system are defined; TD Ni-20Cr characteristics of material used in the current study are compared with previous results; cyclic load, temperature, and pressure effects on sheet material residual strength are investigated; the effects of braze reinforcement in improving the efficiency of spotwelded joints are evaluated; parametric studies of metallic radiative thermal protection systems are reported; and the design, instrumentation, and testing of full scale subsize heat shield panels in two configurations are described. Initial tests of full scale subsize panels included simulated meteoroid impact tests, simulated entry flight aerodynamic heating, programmed differential pressure loads and temperatures simulating mission conditions, and acoustic tests simulating sound levels experienced during boost flight.

40 CFR 201.27 - Procedures for: (1) Determining applicability of the locomotive load cell test stand standard and...

Code of Federal Regulations, 2010 CFR

2010-07-01

... applicability of the locomotive load cell test stand standard and switcher locomotive standard by noise measurement on a receiving property; (2) measurement of locomotive load cell test stands more than 120 meters... locomotive load cell test stand standard and switcher locomotive standard by noise measurement on a receiving...

40 CFR 201.27 - Procedures for: (1) Determining applicability of the locomotive load cell test stand standard and...

Code of Federal Regulations, 2014 CFR

2014-07-01

... applicability of the locomotive load cell test stand standard and switcher locomotive standard by noise measurement on a receiving property; (2) measurement of locomotive load cell test stands more than 120 meters... locomotive load cell test stand standard and switcher locomotive standard by noise measurement on a receiving...

40 CFR 201.27 - Procedures for: (1) Determining applicability of the locomotive load cell test stand standard and...

Code of Federal Regulations, 2012 CFR

2012-07-01

... applicability of the locomotive load cell test stand standard and switcher locomotive standard by noise measurement on a receiving property; (2) measurement of locomotive load cell test stands more than 120 meters... locomotive load cell test stand standard and switcher locomotive standard by noise measurement on a receiving...

40 CFR 201.27 - Procedures for: (1) Determining applicability of the locomotive load cell test stand standard and...

Code of Federal Regulations, 2011 CFR

2011-07-01

... applicability of the locomotive load cell test stand standard and switcher locomotive standard by noise measurement on a receiving property; (2) measurement of locomotive load cell test stands more than 120 meters... locomotive load cell test stand standard and switcher locomotive standard by noise measurement on a receiving...

40 CFR 201.27 - Procedures for: (1) Determining applicability of the locomotive load cell test stand standard and...

Code of Federal Regulations, 2013 CFR

2013-07-01

... applicability of the locomotive load cell test stand standard and switcher locomotive standard by noise measurement on a receiving property; (2) measurement of locomotive load cell test stands more than 120 meters... locomotive load cell test stand standard and switcher locomotive standard by noise measurement on a receiving...

Fracture-resistant monolithic dental crowns.

PubMed

Zhang, Yu; Mai, Zhisong; Barani, Amir; Bush, Mark; Lawn, Brian

2016-03-01

To quantify the splitting resistance of monolithic zirconia, lithium disilicate and nanoparticle-composite dental crowns. Fracture experiments were conducted on anatomically-correct monolithic crown structures cemented to standard dental composite dies, by axial loading of a hard sphere placed between the cusps. The structures were observed in situ during fracture testing, and critical loads to split the structures were measured. Extended finite element modeling (XFEM), with provision for step-by-step extension of embedded cracks, was employed to simulate full failure evolution. Experimental measurements and XFEM predictions were self-consistent within data scatter. In conjunction with a fracture mechanics equation for critical splitting load, the data were used to predict load-sustaining capacity for crowns on actual dentin substrates and for loading with a sphere of different size. Stages of crack propagation within the crown and support substrate were quantified. Zirconia crowns showed the highest fracture loads, lithium disilicate intermediate, and dental nanocomposite lowest. Dental nanocomposite crowns have comparable fracture resistance to natural enamel. The results confirm that monolithic crowns are able to sustain high bite forces. The analysis indicates what material and geometrical properties are important in optimizing crown performance and longevity. Copyright © 2015 Academy of Dental Materials. All rights reserved.

FRACTURE-RESISTANT MONOLITHIC DENTAL CROWNS

PubMed Central

Zhang, Yu; Mai, Zhisong; Barani, Amir; Bush, Mark; Lawn, Brian

2016-01-01

Objective To quantify the splitting resistance of monolithic zirconia, lithium disilicate and nanoparticle-composite dental crowns. Methods Fracture experiments were conducted on anatomically-correct monolithic crown structures cemented to standard dental composite dies, by axial loading of a hard sphere placed between the cusps. The structures were observed in situ during fracture testing, and critical loads to split the structures were measured. Extended finite element modeling (XFEM), with provision for step-by-step extension of embedded cracks, was employed to simulate full failure evolution. Results Experimental measurements and XFEM predictions were self consistent within data scatter. In conjunction with a fracture mechanics equation for critical splitting load, the data were used to predict load-sustaining capacity for crowns on actual dentin substrates and for loading with a sphere of different size. Stages of crack propagation within the crown and support substrate were quantified. Zirconia crowns showed the highest fracture loads, lithium disilicate intermediate, and dental nanocomposite lowest. Dental nanocomposite crowns have comparable fracture resistance to natural enamel. Significance The results confirm that monolithic crowns are able to sustain high bite forces. The analysis indicates what material and geometrical properties are important in optimizing crown performance and longevity. PMID:26792623

Nitrogen Critical Loads for an Alpine Meadow Ecosystem on the Tibetan Plateau.

PubMed

Zong, Ning; Shi, Peili; Song, Minghua; Zhang, Xianzhou; Jiang, Jing; Chai, Xi

2016-03-01

Increasing atmospheric nitrogen (N) deposition has the potential to alter plant diversity and thus the function and stability of terrestrial ecosystems. N-limited alpine ecosystems are expected to be particularly susceptible to increasing N deposition. However, little is known about the critical loads and saturation thresholds of ecosystem responses to increasing N deposition on the Tibetan Plateau, despite its importance to ecosystem management. To evaluate the N critical loads and N saturation thresholds in an alpine ecosystem, in 2010, we treated an alpine meadow with five levels of N addition (0, 10, 20, 40, and 80 kg N ha(-1) year(-1)) and characterized plant and soil responses. The results showed that plant species richness and diversity index did not statistically vary with N addition treatments, but they both changed with years. N addition affected plant cover and aboveground productivity, especially for grasses, and soil chemical features. The N critical loads and saturation thresholds, in terms of plant cover and biomass change at the community level, were 8.8-12.7 and 50 kg N ha(-1) year(-1) (including the ambient N deposition rate), respectively. However, pronounced changes in soil inorganic N and net N mineralization occurred under the 20 and 40 kg N ha(-1) year(-1) treatments. Our results indicate that plant community cover and biomass are more sensitive than soil to increasing N inputs. The plant community composition in alpine ecosystems on the Qinghai-Tibetan Plateau may change under increasing N deposition in the future.

High-End Concept Based on Hypersonic Two-Stage Rocket and Electro-Magnetic Railgun to Launch Micro-Satellites Into Low-Earth

NASA Astrophysics Data System (ADS)

Bozic, O.; Longo, J. M.; Giese, P.; Behren, J.

2005-02-01

The electromagnetic railgun technology appears to be an interesting alternative to launch small payloads into Low Earth Orbit (LEO), as this may introduce lower launch costs. A high-end solution, based upon present state of the art technology, has been investigated to derive the technical boundary conditions for the application of such a new system. This paper presents the main concept and the design aspects of such propelled projectile with special emphasis on flight mechanics, aero-/thermodynamics, materials and propulsion characteristics. Launch angles and trajectory optimisation analyses are carried out by means of 3 degree of freedom simulations (3DOF). The aerodynamic form of the projectile is optimised to provoke minimum drag and low heat loads. The surface temperature distribution for critical zones is calculated with DLR developed Navier-Stokes codes TAU, HOTSOSE, whereas the engineering tool HF3T is used for time dependent calculations of heat loads and temperatures on project surface and inner structures. Furthermore, competing propulsions systems are considered for the rocket engines of both stages. The structural mass is analysed mostly on the basis of carbon fibre reinforced materials as well as classical aerospace metallic materials. Finally, this paper gives a critical overview of the technical feasibility and cost of small rockets for such missions. Key words: micro-satellite, two-stage-rocket, railgun, rocket-engines, aero/thermodynamic, mass optimization

Release of Applied Mechanical Loading Stimulates Intercellular Calcium Waves in Drosophila Wing Discs.

PubMed

Narciso, Cody E; Contento, Nicholas M; Storey, Thomas J; Hoelzle, David J; Zartman, Jeremiah J

2017-07-25

Mechanical forces are critical but poorly understood inputs for organogenesis and wound healing. Calcium ions (Ca 2+ ) are critical second messengers in cells for integrating environmental and mechanical cues, but the regulation of Ca 2+ signaling is poorly understood in developing epithelial tissues. Here we report a chip-based regulated environment for microorgans that enables systematic investigations of the crosstalk between an organ's mechanical stress environment and biochemical signaling under genetic and chemical perturbations. This method enabled us to define the essential conditions for generating organ-scale intercellular Ca 2+ waves in Drosophila wing discs that are also observed in vivo during organ development. We discovered that mechanically induced intercellular Ca 2+ waves require fly extract growth serum as a chemical stimulus. Using the chip-based regulated environment for microorgans, we demonstrate that not the initial application but instead the release of mechanical loading is sufficient, but not necessary, to initiate intercellular Ca 2+ waves. The Ca 2+ response depends on the prestress intercellular Ca 2+ activity and not on the magnitude or duration of the mechanical stimulation applied. Mechanically induced intercellular Ca 2+ waves rely on IP 3 R-mediated Ca 2+ -induced Ca 2+ release and propagation through gap junctions. Thus, intercellular Ca 2+ waves in developing epithelia may be a consequence of stress dissipation during organ growth. Copyright © 2017 Biophysical Society. Published by Elsevier Inc. All rights reserved.

Flaw-induced plastic-flow dynamics in bulk metallic glasses under tension

PubMed Central

Chen, S. H.; Yue, T. M.; Tsui, C. P.; Chan, K. C.

2016-01-01

Inheriting amorphous atomic structures without crystalline lattices, bulk metallic glasses (BMGs) are known to have superior mechanical properties, such as high strength approaching the ideal value, but are susceptible to catastrophic failures. Understanding the plastic-flow dynamics of BMGs is important for achieving stable plastic flow in order to avoid catastrophic failures, especially under tension, where almost all BMGs demonstrate limited plastic flow with catastrophic failure. Previous findings have shown that the plastic flow of BMGs displays critical dynamics under compression tests, however, the plastic-flow dynamics under tension are still unknown. Here we report that power-law critical dynamics can also be achieved in the plastic flow of tensile BMGs by introducing flaws. Differing from the plastic flow under compression, the flaw-induced plastic flow under tension shows an upward trend in the amplitudes of the load drops with time, resulting in a stable plastic-flow stage with a power-law distribution of the load drop. We found that the flaw-induced plastic flow resulted from the stress gradients around the notch roots, and the stable plastic-flow stage increased with the increase of the stress concentration factor ahead of the notch root. The findings are potentially useful for predicting and avoiding the catastrophic failures in tensile BMGs by tailoring the complex stress fields in practical structural-applications. PMID:27779221

The Effect of Indenter Ball Radius on the Static Load Capacity of the Superelastic 60NiTi for Rolling Element Bearings

NASA Technical Reports Server (NTRS)

Dellacorte, Christopher; Moore, Lewis E.

2014-01-01

Static load capacity is a critical design parameter for rolling element bearings used in space mechanisms because of the potential for Brinell (surface dent) damage due to shock and vibration loading events during rocket launch. Brinell damage to bearing raceways can lead to torque variations (noise) and reduced bearing life. The growing use of ceramic rolling elements with high stiffness in hybrid bearings exacerbates the situation. A new family of hard yet resilient materials based upon nickel-titanium is emerging to address such bearing challenges. 60NiTi is a superelastic material that simultaneously exhibits high hardness and a relatively low elastic modulus (approx. 100 GPa) and has been shown to endure higher indentation loads than conventional and high performance steel. Indentation load capacity has been reported for relatively large (12.7 mm diameter) ceramic (Si3N4) indenter balls pressed against flat plates of 60NiTi. In order to develop damage load threshold criteria applicable to a wide range of bearing designs and sizes, the effects of indenter ball radius and the accuracy of interpolation of the Hertz contact stress relations for 60NiTi must be ascertained. In this paper, results of indentation tests involving ceramic balls ranging from 6.4 to 12.7 mm in diameter and highly polished 60NiTi flat plates are presented. When the resulting dent depth data for all the indenter ball sizes are normalized using the Hertz equations, the data (dent depth versus stress) are comparable. Thus when designing bearings made from 60NiTi, the Hertz stress relations can be applied with relative confidence over a range of rolling element sizes and internal geometries.

The Effect of Indenter Ball Radius on the Static Load Capacity of the Superelastic 60NiTi for Rolling Element Bearings

NASA Technical Reports Server (NTRS)

Dellacorte, Christopher; Moore, Lewis E.; Clifton, Joshua S.

2014-01-01

Static load capacity is a critical design parameter for rolling element bearings used in space mechanisms because of the potential for Brinell (surface dent) damage due to shock and vibration loading events during rocket launch. Brinell damage to bearing raceways can lead to torque variations (noise) and reduced bearing life. The growing use of ceramic rolling elements with high stiffness in hybrid bearings exacerbates the situation. A new family of hard yet resilient materials based upon nickel-titanium is emerging to address such bearing challenges. 60NiTi is a superelastic material that simultaneously exhibits high hardness and a relatively low elastic modulus (100GPa) and has been shown to endure higher indentation loads than conventional and high performance steel. Indentation load capacity has been reported for relatively large (12.7mm diameter) ceramic (Si3N4) indenter balls pressed against flat plates of 60NiTi. In order to develop damage load threshold criteria applicable to a wide range of bearing designs and sizes, the effects of indenter ball radius and the accuracy of interpolation of the Hertz contact stress relations for 60NiTi must be ascertained. In this paper, results of indentation tests involving ceramic balls ranging from 6.4 to 12.7mm in diameter and highly polished 60NiTi flat plates are presented. When the resulting dent depth data for all the indenter ball sizes are normalized using the Hertz equations, the data (dent depth vs. stress) are comparable. Thus when designing bearings made from 60NiTi, the Hertz stress relations can be applied with relative confidence over a range of rolling element sizes and internal geometries.

Buckling of Thin Cylindrical Shell Subject to Uniform External Pressure

DOE Office of Scientific and Technical Information (OSTI.GOV)

Forasassi, G.; Lo Frano, R.

2006-07-01

The buckling of cylindrical shells under uniform external pressure loading has been widely investigated. In general, when tubes are subjected to external pressure, collapse is initiated by yielding, but interaction with instability is significant, in that imperfections associated with fabrication of shells reduce the load bearing capacity by a significant amount even when thickness is considerable. A specific buckling analysis is used to predict collapse failure of long pressure vessels and pipelines when they are subjected to external over-pressure. The problem of buckling for variable load conditions is relevant for the optimisation of several Nuclear Power Plant applications as, formore » instance, the IRIS (International Reactor Innovative and Secure) LWR integrated Steam Generator (SG) tubes. In this paper, we consider in addition to the usual assumptions of thin shell, homogeneous and isotropic material, also the tube geometric imperfections and plastic deformations that may affect the limit load. When all those conditions are considered at present, a complete theoretical analysis was not founding the literature. At Pisa University a research activity is being carried out on the buckling of thin walled metal specimen, with reference to several geometries and two different stainless steel materials. A test equipment (with the necessary data acquisition facility), suitable for carrying out many test on this issue, as well as numerical models implemented on the MARC FEM code, were set up. In this report, the results of the performed analyses of critical pressure load determination with different numerical and experimental approaches are presented. The numerical results obtained are compared with the experimental results, for the same geometry and loading conditions, showing a good agreement between these two approaches. (authors)« less

Effects on fatigue life of gate valves due to higher torque switch settings during operability testing

DOE Office of Scientific and Technical Information (OSTI.GOV)

Richins, W.D.; Snow, S.D.; Miller, G.K.

1995-12-01

Some motor operated valves now have higher torque switch settings due to regulatory requirements to ensure valve operability with appropriate margins at design basis conditions. Verifying operability with these settings imposes higher stem loads during periodic inservice testing. These higher test loads increase stresses in the various valve internal parts which may in turn increase the fatigue usage factors. This increased fatigue is judged to be a concern primarily in the valve disks, seats, yokes, stems, and stem nuts. Although the motor operators may also have significantly increased loading, they are being evaluated by the manufacturers and are beyond themore » scope of this study. Two gate valves representative of both relatively weak and strong valves commonly used in commercial nuclear applications were selected for fatigue analyses. Detailed dimensional and test data were available for both valves from previous studies at the Idaho National Engineering Laboratory. Finite element models were developed to estimate maximum stresses in the internal parts of the valves and to identity the critical areas within the valves where fatigue may be a concern. Loads were estimated using industry standard equations for calculating torque switch settings prior and subsequent to the testing requirements of USNRC Generic Letter 89--10. Test data were used to determine both; (1) the overshoot load between torque switch trip and final seating of the disk during valve closing and (2) the stem thrust required to open the valves. The ranges of peak stresses thus determined were then used to estimate the increase in the fatigue usage factors due to the higher stem thrust loads. The usages that would be accumulated by 100 base cycles plus one or eight test cycles per year over 40 and 60 years of operation were calculated.« less

RNA-based micelles: A novel platform for paclitaxel loading and delivery.

PubMed

Shu, Yi; Yin, Hongran; Rajabi, Mehdi; Li, Hui; Vieweger, Mario; Guo, Sijin; Shu, Dan; Guo, Peixuan

2018-04-28

RNA can serve as powerful building blocks for bottom-up fabrication of nanostructures for biotechnological and biomedical applications. In addition to current self-assembly strategies utilizing base pairing, motif piling and tertiary interactions, we reported for the first time the formation of RNA based micellar nanoconstruct with a cholesterol molecule conjugated onto one helical end of a branched pRNA three-way junction (3WJ) motif. The resulting amphiphilic RNA micelles consist of a hydrophilic RNA head and a covalently linked hydrophobic lipid tail that can spontaneously assemble in aqueous solution via hydrophobic interaction. Taking advantage of pRNA 3WJ branched structure, the assembled RNA micelles are capable of escorting multiple functional modules. As a proof of concept for delivery for therapeutics, Paclitaxel was loaded into the RNA micelles with significantly improved water solubility. The successful construction of the drug loaded RNA micelles was confirmed and characterized by agarose gel electrophoresis, atomic force microscopy (AFM), dynamic light scattering (DLS), and fluorescence Nile Red encapsulation assay. The estimate critical micelle formation concentration ranges from 39 nM to 78 nM. The Paclitaxel loaded RNA micelles can internalize into cancer cells and inhibit their proliferation. Further studies showed that the Paclitaxel loaded RNA micelles induced cancer cell apoptosis in a Caspase-3 dependent manner but RNA micelles alone exhibited low cytotoxicity. Finally, the Paclitaxel loaded RNA micelles targeted to tumor in vivo without accumulation in healthy tissues and organs. There is also no or very low induction of pro-inflammatory response. Therefore, multivalence, cancer cell permeability, combined with controllable assembly, low or non toxic nature, and tumor targeting are all promising features that make our pRNA micelles a suitable platform for potential drug delivery. Copyright © 2018 Elsevier B.V. All rights reserved.

The Effect of Indenter Ball Radius on the Static Load Capacity of the Superelastic 60NiTi for Rolling Element Bearings

NASA Technical Reports Server (NTRS)

DellaCorte, Christopher; Moore, Lewis E., III; Clifton, Joshua S.

2014-01-01

Static load capacity is a critical design parameter for rolling element bearings used in space mechanisms because of the potential for Brinell (surface dent) damage due to shock and vibration loading events during rocket launch. Brinell damage to bearing raceways can lead to torque variations (noise) and reduced bearing life. The growing use of ceramic rolling elements with high stiffness in hybrid bearings exacerbates the situation. A new family of hard yet resilient materials based upon nickel-titanium is emerging to address such bearing challenges. 60NiTi is a superelastic material that simultaneously exhibits high hardness and a relatively low elastic modulus (approx. 100 GigaPascals) and has been shown to endure higher indentation loads than conventional and high performance steel. Indentation load capacity has been reported for relatively large (12.7 millimeters diameter) ceramic (Si3N4) indenter balls pressed against flat plates of 60NiTi. In order to develop damage load threshold criteria applicable to a wide range of bearing designs and sizes, the effects of indenter ball radius and the accuracy of interpolation of the Hertz contact stress relations for 60NiTi must be ascertained. In this paper, results of indentation tests involving ceramic balls ranging from 6.4 to 12.7 mm in diameter and highly polished 60NiTi flat plates are presented. When the resulting dent depth data for all the indenter ball sizes are normalized using the Hertz equations, the data (dent depth versus stress) are comparable. Thus when designing bearings made from 60NiTi, the Hertz stress relations can be applied with relative confidence over a range of rolling element sizes and internal geometries.

Bioactive glass in tissue engineering

PubMed Central

Rahaman, Mohamed N.; Day, Delbert E.; Bal, B. Sonny; Fu, Qiang; Jung, Steven B.; Bonewald, Lynda F.; Tomsia, Antoni P.

2011-01-01

This review focuses on recent advances in the development and use of bioactive glass for tissue engineering applications. Despite its inherent brittleness, bioactive glass has several appealing characteristics as a scaffold material for bone tissue engineering. New bioactive glasses based on borate and borosilicate compositions have shown the ability to enhance new bone formation when compared to silicate bioactive glass. Borate-based bioactive glasses also have controllable degradation rates, so the degradation of the bioactive glass implant can be more closely matched to the rate of new bone formation. Bioactive glasses can be doped with trace quantities of elements such as Cu, Zn and Sr, which are known to be beneficial for healthy bone growth. In addition to the new bioactive glasses, recent advances in biomaterials processing have resulted in the creation of scaffold architectures with a range of mechanical properties suitable for the substitution of loaded as well as non-loaded bone. While bioactive glass has been extensively investigated for bone repair, there has been relatively little research on the application of bioactive glass to the repair of soft tissues. However, recent work has shown the ability of bioactive glass to promote angiogenesis, which is critical to numerous applications in tissue regeneration, such as neovascularization for bone regeneration and the healing of soft tissue wounds. Bioactive glass has also been shown to enhance neocartilage formation during in vitro culture of chondrocyte-seeded hydrogels, and to serve as a subchondral substrate for tissue-engineered osteochondral constructs. Methods used to manipulate the structure and performance of bioactive glass in these tissue engineering applications are analyzed. PMID:21421084

The effect of contact stresses in four-point bend testing of graphite/epoxy and graphite/PMR-15 composite beams

NASA Technical Reports Server (NTRS)

Binienda, Wieslaw K.; Roberts, Gary D.; Papadopoulos, Demetrios S.

1992-01-01

The results of in-plane four-point bend experiments on unidirectionally reinforced composite beams are presented for graphite/epoxy (T300/934) and graphite/polyimide (G30-500/PMR-15) composites. The maximum load and the location of cracks formed during failure were measured for testpieces with fibers oriented at various angles to the beam axis. Since most of the beams failed near one or more of the load points, the strength of the beams was evaluated in terms of a proposed model, for the local stress distribution. In this model, an exact solution to the problem of a localized contact force acting on a unidirectionally reinforced half plane is used to describe the local stress field. The stress singularity at the load points is treated in a manner similar to the stress singularity at a crack tip in fracture mechanisms problems. Using this approach, the effect of fiber angle and elastic material properties on the strength of the beam is described in terms of a load intensity factor. For fiber angles less than 45 deg from the beam axis, a single crack is initiated near one of the load points at a critical value of the load intensity factor. The critical load intensity factor decreases with the increasing fiber angle. For larger fiber angles, multiple cracks occur at locations both near and away from the load points, and the load intensity factor at failure increases sharply with increasing fiber angle.

Effect of contact stresses in four-point bend testing of graphite/epoxy and graphite/PMR-15 composite beams

NASA Technical Reports Server (NTRS)

Binienda, W. K.; Roberts, G. D.; Papadopoulos, D. S.

1992-01-01

The results of in-plane four-point bend experiments on unidirectionally reinforced composite beams are presented for graphite/epoxy (T300/934) and graphite/polyimide (G30-500/PMR-15) composites. The maximum load and the location of cracks formed during failure were measured for testpieces with fibers oriented at various angles to the beam axis. Since most of the beams failed near one or more of the load points, the strength of the beams was evaluated in terms of a proposed model for the local stress distribution. In this model, an exact solution to the problem of a localized contact force acting on a unidirectionally reinforced half plane is used to describe the local stress field. The stress singularity at the load points is treated in a manner similar to the stress singularity at a crack tip in fracture mechanisms problems. Using this approach, the effect of fiber angle and elastic material properties on the strength of the beam is described in terms of a load intensity factor. For fiber angles less than 45 deg from the beam axis, a single crack is initiated near one of the load points at a critical value of the load intensity factor. The critical load intensity factor decreases with increasing fiber angle. For larger fiber angles, multiple cracks occur at locations both near and away from the load points, and the load intensity factor at failure increases sharply with increasing fiber angle.

Analysis of multifunctional piezoelectric metastructures for low-frequency bandgap formation and energy harvesting

NASA Astrophysics Data System (ADS)

Sugino, C.; Erturk, A.

2018-05-01

Vibration-based energy harvesting is a growing field for generating low-power electricity to use in wireless electronic devices, such as the sensor networks used in structural health monitoring applications. Locally resonant metastructures, which are structures that comprise locally resonant metamaterial components, enable bandgap formation at wavelengths much longer than the lattice size, for critical applications such as low-frequency vibration attenuation in flexible structures. This work aims to bridge the domains of energy harvesting and locally resonant metamaterials to form multifunctional structures that exhibit both low-power electricity generation and vibration attenuation capabilities. A fully coupled electromechanical modeling framework is developed for two characteristic systems and their modal analysis is presented. Simulations are performed to explore the vibration and electrical power frequency response maps for varying electrical load resistance, and optimal loading conditions are presented. Case studies are presented to understand the interaction of bandgap formation and energy harvesting capabilities of this new class of multifunctional energy-harvesting locally resonant metastructures. It is shown that useful energy can be harvested from locally resonant metastructures without significantly diminishing their dramatic vibration attenuation in the locally resonant bandgap. Thus, integrating energy harvesters into a locally resonant metastructure enables a new potential for multifunctional locally resonant metastructures that can host self-powered sensors.

Sericin/Dextran Injectable Hydrogel as an Optically Trackable Drug Delivery System for Malignant Melanoma Treatment.

PubMed

Liu, Jia; Qi, Chao; Tao, Kaixiong; Zhang, Jinxiang; Zhang, Jian; Xu, Luming; Jiang, Xulin; Zhang, Yunti; Huang, Lei; Li, Qilin; Xie, Hongjian; Gao, Jinbo; Shuai, Xiaoming; Wang, Guobin; Wang, Zheng; Wang, Lin

2016-03-01

Severe side effects of cancer chemotherapy prompt developing better drug delivery systems. Injectable hydrogels are an effective site-target system. For most of injectable hydrogels, once delivered in vivo, some properties including drug release and degradation, which are critical to chemotherapeutic effects and safety, are challenging to monitor. Developing a drug delivery system for effective cancer therapy with in vivo real-time noninvasive trackability is highly desired. Although fluorescence dyes are used for imaging hydrogels, the cytotoxicity limits their applications. By using sericin, a natural photoluminescent protein from silk, we successfully synthesized a hydrazone cross-linked sericin/dextran injectable hydrogel. This hydrogel is biodegradable and biocompatible. It achieves efficient drug loading and controlled release of both macromolecular and small molecular drugs. Notably, sericin's photoluminescence from this hydrogel is directly and stably correlated with its degradation, enabling long-term in vivo imaging and real-time monitoring of the remaining drug. The hydrogel loaded with Doxorubicin significantly suppresses tumor growth. Together, the work demonstrates the efficacy of this drug delivery system, and the in vivo effectiveness of this sericin-based optical monitoring strategy, providing a potential approach for improving hydrogel design toward optimal efficiency and safety of chemotherapies, which may be widely applicable to other drug delivery systems.

Fracture behaviors of ceramic tissue scaffolds for load bearing applications

NASA Astrophysics Data System (ADS)

Entezari, Ali; Roohani-Esfahani, Seyed-Iman; Zhang, Zhongpu; Zreiqat, Hala; Dunstan, Colin R.; Li, Qing

2016-07-01

Healing large bone defects, especially in weight-bearing locations, remains a challenge using available synthetic ceramic scaffolds. Manufactured as a scaffold using 3D printing technology, Sr-HT-Gahnite at high porosity (66%) had demonstrated significantly improved compressive strength (53 ± 9 MPa) and toughness. Nevertheless, the main concern of ceramic scaffolds in general remains to be their inherent brittleness and low fracture strength in load bearing applications. Therefore, it is crucial to establish a robust numerical framework for predicting fracture strengths of such scaffolds. Since crack initiation and propagation plays a critical role on the fracture strength of ceramic structures, we employed extended finite element method (XFEM) to predict fracture behaviors of Sr-HT-Gahnite scaffolds. The correlation between experimental and numerical results proved the superiority of XFEM for quantifying fracture strength of scaffolds over conventional FEM. In addition to computer aided design (CAD) based modeling analyses, XFEM was conducted on micro-computed tomography (μCT) based models for fabricated scaffolds, which took into account the geometric variations induced by the fabrication process. Fracture strengths and crack paths predicted by the μCT-based XFEM analyses correlated well with relevant experimental results. The study provided an effective means for the prediction of fracture strength of porous ceramic structures, thereby facilitating design optimization of scaffolds.

A Study of Influencing Factors on the Tensile Response of a Titanium Matrix Composite With Weak Interfacial Bonding

NASA Technical Reports Server (NTRS)

Goldberg, Robert K.; Arnold, Steven M.

2000-01-01

The generalized method of cells micromechanics model is utilized to analyze the tensile stress-strain response of a representative titanium matrix composite with weak interfacial bonding. The fiber/matrix interface is modeled through application of a displacement discontinuity between the fiber and matrix once a critical debonding stress has been exceeded. Unidirectional composites with loading parallel and perpendicular to the fibers are examined, as well as a cross-ply laminate. For each of the laminates studied, analytically obtained results are compared to experimental data. The application of residual stresses through a cool-down process was found to have a significant effect on the tensile response. For the unidirectional laminate with loading applied perpendicular to the fibers, fiber packing and fiber shape were shown to have a significant effect on the predicted tensile response. Furthermore, the interface was characterized through the use of semi-emperical parameters including an interfacial compliance and a "debond stress;" defined as the stress level across the interface which activates fiber/matrix debonding. The results in this paper demonstrate that if architectural factors are correctly accounted for and the interface is appropriately characterized, the macro-level composite behavior can be correctly predicted without modifying any of the fiber or matrix constituent properties.

Thermal decomposition behavior of nano/micro bimodal feedstock with different solids loading

NASA Astrophysics Data System (ADS)

Oh, Joo Won; Lee, Won Sik; Park, Seong Jin

2018-01-01

Debinding is one of the most critical processes for powder injection molding. The parts in debinding process are vulnerable to defect formation, and long processing time of debinding decreases production rate of whole process. In order to determine the optimal condition for debinding process, decomposition behavior of feedstock should be understood. Since nano powder affects the decomposition behavior of feedstock, nano powder effect needs to be investigated for nano/micro bimodal feedstock. In this research, nano powder effect on decomposition behavior of nano/micro bimodal feedstock has been studied. Bimodal powders were fabricated with different ratios of nano powder, and the critical solids loading of each powder was measured by torque rheometer. Three different feedstocks were fabricated for each powder depending on solids loading condition. Thermogravimetric analysis (TGA) experiment was carried out to analyze the thermal decomposition behavior of the feedstocks, and decomposition activation energy was calculated. The result indicated nano powder showed limited effect on feedstocks in lower solids loading condition than optimal range. Whereas, it highly influenced the decomposition behavior in optimal solids loading condition by causing polymer chain scission with high viscosity.

46 CFR 42.11-10 - Applications for load line assignments and certificates for vessels other than U.S.-flag vessels.

Code of Federal Regulations, 2011 CFR

2011-10-01

... OF HOMELAND SECURITY (CONTINUED) LOAD LINES DOMESTIC AND FOREIGN VOYAGES BY SEA Applications for Load... certificate for a foreign vessel belonging to (or which will belong to) either a country ratifying or acceding to the International Convention on Load Lines, 1966, or to a country with which the United States of...

46 CFR 42.11-10 - Applications for load line assignments and certificates for vessels other than U.S.-flag vessels.

Code of Federal Regulations, 2010 CFR

2010-10-01

... OF HOMELAND SECURITY (CONTINUED) LOAD LINES DOMESTIC AND FOREIGN VOYAGES BY SEA Applications for Load... certificate for a foreign vessel belonging to (or which will belong to) either a country ratifying or acceding to the International Convention on Load Lines, 1966, or to a country with which the United States of...

The Aerodynamic and Dynamic Loading of a Slender Structure by an Impacting Tornado-Like Vortex: The Influence of Relative Vortex-to-Structure Size on Structural Loading

NASA Astrophysics Data System (ADS)

Strasser, Matthew N.

Structural loading produced by an impacting vortex is a hazardous phenomenon that is encountered in numerous applications ranging from the destruction of residences by tornados to the chopping of tip vortices by rotors. Adequate design of structures to resist vortex-induced structural loading necessitates study of the phenomenon that control the structural loading produced by an impacting vortex. This body of work extends the current knowledge base of vortex-structure interaction by evaluating the influence of the relative vortex-to-structure size on the structural loading that the vortex produces. A computer model is utilized to directly simulate the two-dimensional impact of an impinging vortex with a slender, cylindrical structure. The vortex's tangential velocity profile (TVP) is defined by a normalization of the Vatistas analytical (TVP) which realistically replicates the documented spectrum of measured vortex TVPs. The impinging vortex's maximum tangential velocity is fixed, and the vortex's critical radius is incremented from one to one-hundred times the structure's diameter. When the impinging vortex is small, it interacts with vortices produced on the structure by the free stream, and maximum force coefficient amplitudes vary by more than 400% when the impinging vortex impacts the structure at different times. Maximum drag and lift force coefficient amplitudes reach asymptotic values as the impinging vortex's size increases that are respectively 94.77% and 10.66% less than maximum force coefficients produced by an equivalent maximum velocity free stream. The vortex produces maximum structural loading when its path is shifted above the structure's centerline, and maximum drag and lift force coefficients are respectively up to 4.80% and 34.07% greater than maximum force coefficients produced by an equivalent-velocity free stream. Finally, the dynamic load factor (DLF) concept is used to develop a generalized methodology to assess the dynamic amplification of a structure's response to vortex loading and to assess the dynamic loading threat that tornados pose. Typical civil and residential structures will not experience significant response amplification, but responses of very flexible structures may be amplified by up to 2.88 times.

Applying graph partitioning methods in measurement-based dynamic load balancing

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bhatele, Abhinav; Fourestier, Sebastien; Menon, Harshitha

Load imbalance leads to an increasing waste of resources as an application is scaled to more and more processors. Achieving the best parallel efficiency for a program requires optimal load balancing which is a NP-hard problem. However, finding near-optimal solutions to this problem for complex computational science and engineering applications is becoming increasingly important. Charm++, a migratable objects based programming model, provides a measurement-based dynamic load balancing framework. This framework instruments and then migrates over-decomposed objects to balance computational load and communication at runtime. This paper explores the use of graph partitioning algorithms, traditionally used for partitioning physical domains/meshes, formore » measurement-based dynamic load balancing of parallel applications. In particular, we present repartitioning methods developed in a graph partitioning toolbox called SCOTCH that consider the previous mapping to minimize migration costs. We also discuss a new imbalance reduction algorithm for graphs with irregular load distributions. We compare several load balancing algorithms using microbenchmarks on Intrepid and Ranger and evaluate the effect of communication, number of cores and number of objects on the benefit achieved from load balancing. New algorithms developed in SCOTCH lead to better performance compared to the METIS partitioners for several cases, both in terms of the application execution time and fewer number of objects migrated.« less

Curcumin-loaded mixed micelles: preparation, optimization, physicochemical properties and cytotoxicity in vitro.

PubMed

Duan, Yuwei; Wang, Juan; Yang, Xiaoye; Du, Hongliang; Xi, Yanwei; Zhai, Guangxi

2015-01-01

Although curcumin (CUR) can inhibit proliferation and induce apoptosis of tumors, the poor water solubility restricted its clinical application. The aim of this study was to improve the aqueous solubility of CUR and make more favorable changes to bioactivity by preparing curcumin-loaded phospholipid-sodium deoxycholate-mixed micelles (CUR-PC-SDC-MMs). CUR-PC-SDC-MMs were prepared by the thin-film dispersion method. Based on the results of single factor exploration, the preparation technology was optimized using the central composite design-response surface methodology with drug loading and entrapment efficiency (EE%) as indicators. The images of transmission electron microscopy showed that the optimized CUR-PC-SDC-MMs were spherical and well dispersed. The average size of the mixed micelles was 66.5 nm, the zeta potential was about -26.96 mV and critical micelle concentration was 0.0087 g/l. CUR was encapsulated in PC-SDC-MMs with loading capacity of 13.12%, EE% of 87.58%, and the solubility of CUR in water was 3.14 mg/ml. The release results in vitro showed that the mixed micelles presented sustained release behavior compared to the propylene glycol solution of CUR. The IC50 values of CUR-loaded micelles and free drug in human breast carcinoma cell lines were 4.10 μg/ml and 6.93 µg/ml, respectively. It could be concluded from the above results that the CUR-PC-SDC-MMs system might serve as a promising nanocarrier to improve the solubility and bioactivity of CUR.

The impact of hybrid energy storage on power quality, when high power pulsed DC loads are operated on a microgrid testbed

NASA Astrophysics Data System (ADS)

Kelley, Jay Paul

As the Navy's demands for high power transient loads evolves, so too does the need for alternative energy sources to back-up the more traditional power generation. Such applications in need of support include electrical grid backup and directed energy weapon systems such as electromagnetic launchers, laser systems, and high power microwave generators, among others. Among the alternative generation sources receiving considerable attention are energy storage devices such as rechargeable electrochemical batteries and capacitors. In such applications as those mentioned above, these energy storage devices offer the ability to serve a dual role as both a power source to the various loads as well high power loads themselves to the continual generation when the high power transient loads are in periods of downtime. With the recent developments in electrochemical energy storage, lithium-ion batteries (LIBs) seem like the obvious choice, but previous research has shown that the elevated rates of charging can be detrimental to both the cycle life and the operational life span of the device. In order to preserve the batteries, their charge rate must be limited. One proposed method to accomplish the dual role task mentioned above, while preserving the life of the batteries, is by combining high energy density LIBs with high power density electric double layer capacitors (EDLCs) or lithium-ion capacitors (LICs) using controllable power electronics to adjust the flow of power to and from each device. Such a configuration is typically referred to as hybrid energy storage module (HESM). While shipboard generators start up, the combined high energy density and high power density of the HESM provides the capability to source critical loads for an extended period of time at the high rates they demand. Once the generator is operationally efficient, the HESM can act as a high energy reservoir to harvest the energy from the generator while the loads are in short periods of inactivity. This enables the generator to maintain its operation at levels of high efficiency thereby increasing the power quality of the AC bus. The work discussed here is aimed at evaluating how the use of energy storage impacts the power quality on MicroGrid's AC bus when high rate DC and AC loads are sourced simultaneously. Also HESM has been developed and evaluated as a mean to optimizing both the power and energy density of the energy storage installed.

Design Considerations of a Transverse Flux Machine for Direct-Drive Wind Turbine Applications

DOE Office of Scientific and Technical Information (OSTI.GOV)

Husain, Tausif; Hasan, Iftekhar; Sozer, Yilmaz

This paper presents the design considerations of a double-sided transverse flux machine (TFM) for direct-drive wind turbine applications. The proposed TFM has a modular structure with quasi-U stator cores and toroidal ring windings. The rotor is constructed with ferrite magnets in a flux-concentrating setup to achieve high air gap flux density. Pole number selection is critical in the design process of a TFM as it affects both the torque density and power factor under fixed magnetic and changing electrical loading. Several key design ratios are introduced to facilitate the initial design procedure. The effect of pole shaping on back-EMF andmore » inductance is also analyzed. These investigations provide guidance toward the required design of a TFM for direct-drive applications. The analyses are carried out using analytical and three-dimensional finite element analysis (FEA). A proof-of-concept prototype was developed to experimentally validate the FEA results.« less

Design Considerations of a Transverse Flux Machine for Direct-Drive Wind Turbine Applications

DOE PAGES

Husain, Tausif; Hasan, Iftekhar; Sozer, Yilmaz; ...

2018-03-12

This paper presents the design considerations of a double-sided transverse flux machine (TFM) for direct-drive wind turbine applications. The proposed TFM has a modular structure with quasi-U stator cores and toroidal ring windings. The rotor is constructed with ferrite magnets in a flux-concentrating setup to achieve high air gap flux density. Pole number selection is critical in the design process of a TFM as it affects both the torque density and power factor under fixed magnetic and changing electrical loading. Several key design ratios are introduced to facilitate the initial design procedure. The effect of pole shaping on back-EMF andmore » inductance is also analyzed. These investigations provide guidance toward the required design of a TFM for direct-drive applications. The analyses are carried out using analytical and three-dimensional finite element analysis (FEA). A proof-of-concept prototype was developed to experimentally validate the FEA results.« less

National Aeronautics and Space Administration (NASA) Earth Science Research for Energy Management. Part 1; Overview of Energy Issues and an Assessment of the Potential for Application of NASA Earth Science Research

NASA Technical Reports Server (NTRS)

Zell, E.; Engel-Cox, J.

2005-01-01

Effective management of energy resources is critical for the U.S. economy, the environment, and, more broadly, for sustainable development and alleviating poverty worldwide. The scope of energy management is broad, ranging from energy production and end use to emissions monitoring and mitigation and long-term planning. Given the extensive NASA Earth science research on energy and related weather and climate-related parameters, and rapidly advancing energy technologies and applications, there is great potential for increased application of NASA Earth science research to selected energy management issues and decision support tools. The NASA Energy Management Program Element is already involved in a number of projects applying NASA Earth science research to energy management issues, with a focus on solar and wind renewable energy and developing interests in energy modeling, short-term load forecasting, energy efficient building design, and biomass production.

Biodegradable black phosphorus-based nanomaterials in biomedicine: theranostic applications.

PubMed

Wang, Zhen; Liu, Zhiming; Su, Chengkang; Yang, Biwen; Fei, Xixi; Li, Yi; Hou, Yuqing; Zhao, Henan; Guo, Yanxian; Zhuang, Zhengfei; Zhong, Huiqing; Guo, Zhouyi

2017-09-20

Ascribe to the unique two-dimensional planar nanostructure with exceptional physical and chemical properties, black phosphorous (BP) as the emerging inorganic two-dimensional nanomaterial with high biocompatibility and degradability has been becoming one of the most promising materials of great potentials in biomedicine. The exfoliated BP sheets possess ultra-high surface area available for valid bio-conjugation and molecular loading for chemotherapy. Utilizing the intrinsic near-infrared optical absorbance, BP-based photothermal therapy in vivo, photodynamic therapy and biomedical imaging has been realized, achieving unprecedented anti-tumor therapeutic efficacy in animal experiments. Additionally, the BP nanosheets can strongly react with oxygen and water, and finally degrade to non-toxic phosphate and phosphonate in the aqueous solution. This manuscript aimed to summarize the preliminary progresses on theranostic application of BP and its derivatives black phosphorus quantum dots (BPQDs), and discussed the prospects and the state-of-art unsolved critical issues of using BP-based material for theranostic applications. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

Nanostructured porous silicon-mediated drug delivery.

PubMed

Martín-Palma, Raúl J; Hernández-Montelongo, Jacobo; Torres-Costa, Vicente; Manso-Silván, Miguel; Muñoz-Noval, Álvaro

2014-08-01

The particular properties of nanostructured porous silicon (nanoPS) make it an attractive material for controlled and localized release of therapeutics within the body, aiming at increased efficacy and reduced risks of potential side effects. Since this is a rapidly evolving field as a consequence of the number of research groups involved, a critical review of the state of the art is necessary. In this work, the most promising and successful applications of nanoPS in the field of drug delivery are reviewed and discussed. Two key issues such as drug loading and release are also analyzed in detail. The development of multifunctional (hybrid) systems, aiming at imparting additional functionalities to the nanoPS particles such as luminescence, magnetic response and/or plasmonic effects (allowing simultaneous tracking and guiding), is also examined. Nanostructured materials based on silicon are promising platforms for pharmaceutical applications given their ability to degrade and low toxicity. However, a very limited number of clinical applications have been demonstrated so far.

Ranges of Applicability for the Continuum-beam Model in the Constitutive Analysis of Carbon Nanotubes: Nanotubes or Nano-beams?

NASA Technical Reports Server (NTRS)

Harik, Vasyl Michael; Bushnell, Dennis M. (Technical Monitor)

2001-01-01

Ranges of validity for the continuum-beam model, the length-scale effects and continuum assumptions are analyzed in the framework of scaling analysis of NT structure. Two coupled criteria for the applicability of the continuum model are presented. Scaling analysis of NT buckling and geometric parameters (e.g., diameter and length) is carried out to determine the key non-dimensional parameters that control the buckling strains and modes of NT buckling. A model applicability map, which represents two classes of NTs, is constructed in the space of non-dimensional parameters. In an analogy with continuum mechanics, a mechanical law of geometric similitude is presented for two classes of beam-like NTs having different geometries. Expressions for the critical buckling loads and strains are tailored for the distinct groups of NTs and compared with the data provided by the molecular dynamics simulations. Implications for molecular dynamics simulations and the NT-based scanning probes are discussed.

Non-Markovian State-Dependent Networks in Critical Loading

DTIC Science & Technology

2015-02-04

available for gener- alized Jackson networks; see Reiman [19]. Such limit theorems are useful to obtain approximations to various quantities of...2.1d))—so the limit process is an unconstrained diffusion; see Mandelbaum, Massey, and Reiman [13], Pang, Talreja, and Whitt[16], and references therein...standard critical loading condition that (λn − Rμn)/√n → λ2 − μ2 as n → ∞; cf. Reiman [19]. Lemma 2.1. Let condition (A0) hold and maxi∈IK supx∈IRK+(λ n i

The application of reduced-processing decision support systems to facilitate the acquisition of decision-making skills.

PubMed

Perry, Nathan C; Wiggins, Mark W; Childs, Merilyn; Fogarty, Gerard

2013-06-01

The study was designed to examine whether the availability of reduced-processing decision support system interfaces could improve the decision making of inexperienced personnel in the context of Although research into reduced-processing decision support systems has demonstrated benefits in minimizing cognitive load, these benefits have not typically translated into direct improvements in decision accuracy because of the tendency for inexperienced personnel to focus on less-critical information. The authors investigated whether reduced-processing interfaces that direct users' attention toward the most critical cues for decision making can produce improvements in decision-making performance. Novice participants made incident command-related decisions in experimental conditions that differed according to the amount of information that was available within the interface, the level of control that they could exert over the presentation of information, and whether they had received decision training. The results revealed that despite receiving training, participants improved in decision accuracy only when they were provided with an interface that restricted information access to the most critical cues. It was concluded that an interface that restricts information access to only the most critical cues in the scenario can facilitate improvements in decision performance. Decision support system interfaces that encourage the processing of the most critical cues have the potential to improve the accuracy and timeliness of decisions made by inexperienced personnel.

Georgia Tech Studies of Sub-Critical Advanced Burner Reactors with a D-T Fusion Tokamak Neutron Source for the Transmutation of Spent Nuclear Fuel

NASA Astrophysics Data System (ADS)

Stacey, W. M.

2009-09-01

The possibility that a tokamak D-T fusion neutron source, based on ITER physics and technology, could be used to drive sub-critical, fast-spectrum nuclear reactors fueled with the transuranics (TRU) in spent nuclear fuel discharged from conventional nuclear reactors has been investigated at Georgia Tech in a series of studies which are summarized in this paper. It is found that sub-critical operation of such fast transmutation reactors is advantageous in allowing longer fuel residence time, hence greater TRU burnup between fuel reprocessing stages, and in allowing higher TRU loading without compromising safety, relative to what could be achieved in a similar critical transmutation reactor. The required plasma and fusion technology operating parameter range of the fusion neutron source is generally within the anticipated operational range of ITER. The implications of these results for fusion development policy, if they hold up under more extensive and detailed analysis, is that a D-T fusion tokamak neutron source for a sub-critical transmutation reactor, built on the basis of the ITER operating experience, could possibly be a logical next step after ITER on the path to fusion electrical power reactors. At the same time, such an application would allow fusion to contribute to meeting the nation's energy needs at an earlier stage by helping to close the fission reactor nuclear fuel cycle.

Parallel Processing of Adaptive Meshes with Load Balancing

NASA Technical Reports Server (NTRS)

Das, Sajal K.; Harvey, Daniel J.; Biswas, Rupak; Biegel, Bryan (Technical Monitor)

2001-01-01

Many scientific applications involve grids that lack a uniform underlying structure. These applications are often also dynamic in nature in that the grid structure significantly changes between successive phases of execution. In parallel computing environments, mesh adaptation of unstructured grids through selective refinement/coarsening has proven to be an effective approach. However, achieving load balance while minimizing interprocessor communication and redistribution costs is a difficult problem. Traditional dynamic load balancers are mostly inadequate because they lack a global view of system loads across processors. In this paper, we propose a novel and general-purpose load balancer that utilizes symmetric broadcast networks (SBN) as the underlying communication topology, and compare its performance with a successful global load balancing environment, called PLUM, specifically created to handle adaptive unstructured applications. Our experimental results on an IBM SP2 demonstrate that the SBN-based load balancer achieves lower redistribution costs than that under PLUM by overlapping processing and data migration.

Target loads of atmospheric sulfur deposition for the protection and recovery of acid-sensitive streams in the Southern Blue Ridge Province

Treesearch

Timothy Sullivan; Bernard Cosby; William Jackson

2011-01-01

An important tool in the evaluation of acidification damage to aquatic and terrestrial ecosystems is the critical load (CL), which represents the steady-state level of acidic deposition below which ecological damage would not be expected to occur, according to current scientific understanding. A deposition load intended to be protective of a specified resource...

Splash evaluation of SRB designs

NASA Technical Reports Server (NTRS)

Counter, D. N.

1974-01-01

A technique is developed to optimize the shuttle solid rocket booster (SRB) design for water impact loads. The SRB is dropped by parachute and recovered at sea for reuse. Loads experienced at water impact are design critical. The probability of each water impact load is determined using a Monte Carlo technique and an aerodynamic analysis of the SRB parachute system. Meteorological effects are included and four configurations are evaluated.

MOD-1 Wind Turbine Generator Analysis and Design Report, Volume 2

NASA Technical Reports Server (NTRS)

1979-01-01

The MOD-1 detail design is appended. The supporting analyses presented include a parametric system trade study, a verification of the computer codes used for rotor loads analysis, a metal blade study, and a definition of the design loads at each principal wind turbine generator interface for critical loading conditions. Shipping and assembly requirements, composite blade development, and electrical stability are also discussed.

Effects of interfacial debonding and fiber breakage on static and dynamic buckling of fibers embedded in matrices

NASA Astrophysics Data System (ADS)

Serttunc, Metin

1992-09-01

Analyses were performed for static and dynamic buckling of a continuous fiber embedded in a matrix in order to determine the effects of interfacial debonding and fiber breakage on the critical buckling load and the domain of instability. A beam on elastic foundation model was used. The study showed that a local interfacial debonding between a fiber and a surrounding matrix resulted in an increase of the wavelength of the buckling mode. An increase of the wave length yielded a decrease of the static buckling load and lowered the dynamic instability domain. In general, the effect of a partial or complete interfacial debonding was more significant on the domain of dynamic instability than on the effects of static buckling load. For dynamic buckling of a fiber, a local debonding of size 10 to 20 percent of the fiber length had the most important influence on the domains of dynamic instability regardless of the location of debonding and the boundary conditions of the fiber. For static buckling, the location of a local debonding was critical to a free-simply supported fiber but not to a fiber with both ends simply supported. Fiber breakage also lowered the critical buckling load significantly.

The effects of display variables and secondary loading on the dual axis critical task performance

NASA Technical Reports Server (NTRS)

Swisher, G. M.; Nataraj, S.

1973-01-01

The effects of scanning displays for separated instruments, separated versus combined displays, and the effects of secondary loading are investigated. An operator rating scale for handling qualities is established analogous to the Cooper Harper Scale.

Resistance factors for 100% dynamic testing, with and without static load tests : [summary].

DOT National Transportation Integrated Search

2011-01-01

The Federal Highway Administration (FHWA) and : most state departments of transportation have : adopted the Load and Resistance Factor (LRFD) : approach to design. Critical to the design of : piles in this approach is the development of a : resistanc...

Embedded data collector (EDC) evaluation, phase II - comparison with instrumented static load tests : [technical summary].

DOT National Transportation Integrated Search

2013-12-01

Monitoring installation of driven pile foundations : is critically important to ensure adequate safety : of structures with piles, such as the many bridges : which are maintained by the Florida Department : of Transportation (FDOT). Dynamic load test...

Stormwater Pollutant Control from Critical Source Areas

EPA Science Inventory

Critical source areas include: vehicular maintenance facilities, parking lots and bus terminals, junk and lumber yards, industrial storage facilities, loading docks and refueling areas, manufacturing sites, etc. Addressing pollutant runoff from these areas is an important compon...

Surface water acidification responses and critical loads of sulfur and nitrogen deposition in Loch Vale watershed, Colorado

USGS Publications Warehouse

Sullivan, T.J.; Cosby, B.J.; Tonnessen, K.A.; Clow, D.W.

2005-01-01

We evaluated the sensitivity of The Loch, a subalpine lake in Rocky Mountain National Park in Colorado, to acidification in response to increased atmospheric loading of sulfur (S) and nitrogen (N) using the Model of Acidification of Groundwater in Catchments (MAGIC). Lake water acid‐base chemistry was moderately sensitive to changes in both S and N deposition. However, the loads of S deposition that would drive chronic lake water acid neutralizing capacity (ANC) to below 0 or 20 μeq L−1 were estimated to be 11 and 8 kg S ha−1 yr−1, respectively, assuming constant future N deposition at current levels. Comparable loads for N deposition, assuming constant future S deposition, were estimated to be 21 and 12 kg N ha−1 yr−1, respectively. Modeling results for Andrews Creek, an alpine tributary to The Loch, suggested critical loads for surface water acidification that averaged about one third lower. Surface water ANC = 50 μeq L−1 was projected to occur in 50 years in The Loch if S or N deposition increased by a moderate amount (<40%) but could not be achieved in Andrews Creek by reducing either S or N deposition to zero. On the basis of the results of synoptic surveys of lake water chemistry, about one fifth of the wilderness lakes in the Colorado Front Range are more acid‐sensitive than The Loch. This modeling exercise suggests the need for a regional analysis of critical loads for the larger population of acid‐sensitive aquatic resources in order to provide part of the scientific foundation for federally mandated land management decisions.

Safety Criticality Standards Using the French CRISTAL Code Package: Application to the AREVA NP UO{sub 2} Fuel Fabrication Plant

DOE Office of Scientific and Technical Information (OSTI.GOV)

Doucet, M.; Durant Terrasson, L.; Mouton, J.

2006-07-01

Criticality safety evaluations implement requirements to proof of sufficient sub critical margins outside of the reactor environment for example in fuel fabrication plants. Basic criticality data (i.e., criticality standards) are used in the determination of sub critical margins for all processes involving plutonium or enriched uranium. There are several criticality international standards, e.g., ARH-600, which is one the US nuclear industry relies on. The French Nuclear Safety Authority (DGSNR and its advising body IRSN) has requested AREVA NP to review the criticality standards used for the evaluation of its Low Enriched Uranium fuel fabrication plants with CRISTAL V0, the recentlymore » updated French criticality evaluation package. Criticality safety is a concern for every phase of the fabrication process including UF{sub 6} cylinder storage, UF{sub 6}-UO{sub 2} conversion, powder storage, pelletizing, rod loading, assembly fabrication, and assembly transportation. Until 2003, the accepted criticality standards were based on the French CEA work performed in the late seventies with the APOLLO1 cell/assembly computer code. APOLLO1 is a spectral code, used for evaluating the basic characteristics of fuel assemblies for reactor physics applications, which has been enhanced to perform criticality safety calculations. Throughout the years, CRISTAL, starting with APOLLO1 and MORET 3 (a 3D Monte Carlo code), has been improved to account for the growth of its qualification database and for increasing user requirements. Today, CRISTAL V0 is an up-to-date computational tool incorporating a modern basic microscopic cross section set based on JEF2.2 and the comprehensive APOLLO2 and MORET 4 codes. APOLLO2 is well suited for criticality standards calculations as it includes a sophisticated self shielding approach, a P{sub ij} flux determination, and a 1D transport (S{sub n}) process. CRISTAL V0 is the result of more than five years of development work focusing on theoretical approaches and the implementation of user-friendly graphical interfaces. Due to its comprehensive physical simulation and thanks to its broad qualification database with more than a thousand benchmark/calculation comparisons, CRISTAL V0 provides outstanding and reliable accuracy for criticality evaluations for configurations covering the entire fuel cycle (i.e. from enrichment, pellet/assembly fabrication, transportation, to fuel reprocessing). After a brief description of the calculation scheme and the physics algorithms used in this code package, results for the various fissile media encountered in a UO{sub 2} fuel fabrication plant will be detailed and discussed. (authors)« less

Opposite effects of capacity load and resolution load on distractor processing.

PubMed

Zhang, Weiwei; Luck, Steven J

2015-02-01

According to the load theory of attention, an increased perceptual load reduces distractor processing whereas an increased working memory load facilitates distractor processing. Here we raise the possibility that the critical distinction may instead be between an emphasis on resolution and an emphasis on capacity. That is, perceptual load manipulations typically emphasize resolution (fine-grained discriminations), whereas working memory load manipulations typically emphasize capacity (simultaneous processing of multiple relevant stimuli). To test the plausibility of this hypothesis, we used a visual working memory task that emphasized either the number of items to be stored (capacity load, retaining 2 vs. 4 colors) or the precision of the representations (resolution load, detecting small vs. large color changes). We found that an increased capacity load led to increased flanker interference (a measure of distractor processing), whereas an increased resolution load led to reduced flanker interference. These opposite effects of capacity load and resolution load on distractor processing mirror the previously described opposite effects of perceptual load and working memory load.

Opposite Effects of Capacity Load and Resolution Load on Distractor Processing

PubMed Central

Zhang, Weiwei; Luck, Steven J.

2014-01-01

According to the load theory of attention, an increased perceptual load reduces distractor processing whereas an increased working memory load facilitates distractor processing. Here we raise the possibility that the critical distinction may instead be between an emphasis on resolution and an emphasis on capacity. That is, perceptual load manipulations typically emphasize resolution (fine-grained discriminations), whereas working memory load manipulations typically emphasize capacity (simultaneous processing of multiple relevant stimuli). To test the plausibility of this hypothesis, we used a visual working memory task that emphasized either the number of items to be stored (capacity load, retaining two versus four colors) or the precision of the representations (resolution load, detecting small versus large color changes). We found that an increased capacity load led to increased flanker interference (a measure of distractor processing), whereas an increased resolution load led to reduced flanker interference. These opposite effects of capacity load and resolution load on distractor processing mirror the previously described opposite effects of perceptual load and working memory load. PMID:25365573

Electromechanical properties of superconductors for DOE fusion applications

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ekin, J.W.; Moreland, J.; Brauch, J.C.

1986-03-01

This is an interim report presenting data on superconductor performance under mechanical load, which are needed for the selection of superconductors and the mechanical design of superconducting magnets for DOE fusion energy systems. A further aim of the reported research is to measure and understand the electromechanical properties of promising new superconductor materials with strong application potential at high magnetic fields. Results include the following. The first strain vs. critical-current studies were made on a Chevrel-phase superconductor, PbMo/sub 6/S/sub 8/. Chevrel-phase superconductors were found to have a large strain effect, comparable in magnitude to A-15 superconductors like Nb/sub 3/Sn. Electromechanical-propertymore » measurements of an experimental liquid-tin-infiltrated Nb/sub 3/Sn conductor showed it to have an irreversible strain limit twice as large as bronze-process supercondutors and a significantly higher overall critical-current denstiy; the liquid-infiltration process thus has the potential for development of a practical Nb/sub 3/Sn conductors with both superior critical-current density and extremely good mechanical properties. Electromechanical parameters were obtained on several Nb/sub 3/Sn conductors that are candidate materials for superconducting fusion magnets, icluding conductors fabricated by the bronze, internal-tin, and jelly-roll processes. Thermal contraction data are reported on several new structural materials for superconductor sheathing and reinforcement, and a new diagnostic tool for probing the energy gap of practical superconductors has been developed using electron tunneling.« less

Shell stability analysis in a computer aided engineering (CAE) environment

NASA Technical Reports Server (NTRS)

Arbocz, J.; Hol, J. M. A. M.

1993-01-01

The development of 'DISDECO', the Delft Interactive Shell DEsign COde is described. The purpose of this project is to make the accumulated theoretical, numerical and practical knowledge of the last 25 years or so readily accessible to users interested in the analysis of buckling sensitive structures. With this open ended, hierarchical, interactive computer code the user can access from his workstation successively programs of increasing complexity. The computational modules currently operational in DISDECO provide the prospective user with facilities to calculate the critical buckling loads of stiffened anisotropic shells under combined loading, to investigate the effects the various types of boundary conditions will have on the critical load, and to get a complete picture of the degrading effects the different shapes of possible initial imperfections might cause, all in one interactive session. Once a design is finalized, its collapse load can be verified by running a large refined model remotely from behind the workstation with one of the current generation 2-dimensional codes, with advanced capabilities to handle both geometric and material nonlinearities.

Residual Strength Predictions with Crack Buckling

NASA Technical Reports Server (NTRS)

Dawicke, D. S.; Gullerud, A. S.; Dodds, R. H., Jr.; Hampton, R. W.

1999-01-01

Fracture tests were conducted on middle crack tension, M(T), and compact tension, C(T), specimens of varying widths, constructed from 0.063 inch thick sheets of 2024-T3 aluminum alloy. Guide plates were used to restrict out-of-plane displacements in about half of the tests. Analyses using the three-dimensional, elastic-plastic finite element code WARP3D simulated the tests with and without guide plates using a critical CTOA fracture criterion. The experimental results indicate that crack buckling reduced the failure loads by up to 40%. Using a critical CTOA value of 5.5 deg., the WARP3D analyses predicted the failure loads for the tests with guide plates within +/- 10% of the experimentally measured values. For the M(T) tests without guide plates, the WARP3D analyses predicted the failure loads for the 12 and 24 inch tests within 10%, while over predicting the failure loads for the 40 inch wide tests by about 20%.

Stormwater runoff pollutant loading distributions and their correlation with rainfall and catchment characteristics in a rapidly industrialized city.

PubMed

Li, Dongya; Wan, Jinquan; Ma, Yongwen; Wang, Yan; Huang, Mingzhi; Chen, Yangmei

2015-01-01

Fast urbanization and industrialization in developing countries result in significant stormwater runoff pollution, due to drastic changes in land-use, from rural to urban. A three-year study on the stormwater runoff pollutant loading distributions of industrial, parking lot and mixed commercial and residential catchments was conducted in the Tongsha reservoir watershed of Dongguan city, a typical, rapidly industrialized urban area in China. This study presents the changes in concentration during rainfall events, event mean concentrations (EMCs) and event pollution loads per unit area (EPLs). The first flush criterion, namely the mass first flush ratio (MFFn), was used to identify the first flush effects. The impacts of rainfall and catchment characterization on EMCs and pollutant loads percentage transported by the first 40% of runoff volume (FF40) were evaluated. The results indicated that the pollutant wash-off process of runoff during the rainfall events has significant temporal and spatial variations. The mean rainfall intensity (I), the impervious rate (IMR) and max 5-min intensity (Imax5) are the critical parameters of EMCs, while Imax5, antecedent dry days (ADD) and rainfall depth (RD) are the critical parameters of FF40. Intercepting the first 40% of runoff volume can remove 55% of TSS load, 53% of COD load, 58% of TN load, and 61% of TP load, respectively, according to all the storm events. These results may be helpful in mitigating stormwater runoff pollution for many other urban areas in developing countries.