Sample records for cross regional cluster

  1. Cross-entropy clustering framework for catchment classification

    NASA Astrophysics Data System (ADS)

    Tongal, Hakan; Sivakumar, Bellie

    2017-09-01

    There is an increasing interest in catchment classification and regionalization in hydrology, as they are useful for identification of appropriate model complexity and transfer of information from gauged catchments to ungauged ones, among others. This study introduces a nonlinear cross-entropy clustering (CEC) method for classification of catchments. The method specifically considers embedding dimension (m), sample entropy (SampEn), and coefficient of variation (CV) to represent dimensionality, complexity, and variability of the time series, respectively. The method is applied to daily streamflow time series from 217 gauging stations across Australia. The results suggest that a combination of linear and nonlinear parameters (i.e. m, SampEn, and CV), representing different aspects of the underlying dynamics of streamflows, could be useful for determining distinct patterns of flow generation mechanisms within a nonlinear clustering framework. For the 217 streamflow time series, nine hydrologically homogeneous clusters that have distinct patterns of flow regime characteristics and specific dominant hydrological attributes with different climatic features are obtained. Comparison of the results with those obtained using the widely employed k-means clustering method (which results in five clusters, with the loss of some information about the features of the clusters) suggests the superiority of the cross-entropy clustering method. The outcomes from this study provide a useful guideline for employing the nonlinear dynamic approaches based on hydrologic signatures and for gaining an improved understanding of streamflow variability at a large scale.

  2. Electron impact ionization cross sections of beryllium-tungsten clusters*

    NASA Astrophysics Data System (ADS)

    Sukuba, Ivan; Kaiser, Alexander; Huber, Stefan E.; Urban, Jan; Probst, Michael

    2016-01-01

    We report calculated electron impact ionization cross sections (EICSs) of beryllium-tungsten clusters, BenW with n = 1,...,12, from the ionization threshold to 10 keV using the Deutsch-Märk (DM) and the binary-encounter-Bethe (BEB) formalisms. The positions of the maxima of DM and BEB cross sections are mostly close to each other. The DM cross sections are more sensitive with respect to the cluster size. For the clusters smaller than Be4W they yield smaller cross sections than BEB and vice versa larger cross sections than BEB for clusters larger than Be6W. The maximum cross section values for the singlet-spin groundstate clusters range from 7.0 × 10-16 cm2 at 28 eV (BeW) to 54.2 × 10-16 cm2 at 43 eV (Be12W) for the DM cross sections and from 13.5 × 10-16 cm2 at 43 eV (BeW) to 38.9 × 10-16 cm2 at 43 eV (Be12W) for the BEB cross sections. Differences of the EICSs in different isomers and between singlet and triplet states are also explored. Both the DM and BEB cross sections could be fitted perfectly to a simple expression used in modeling and simulation codes in the framework of nuclear fusion research. Contribution to the Topical Issue "Atomic Cluster Collisions (7th International Symposium)", edited by Gerardo Delgado Barrio, Andrey Solov'Yov, Pablo Villarreal, Rita Prosmiti.Supplementary material in the form of one pdf file available from the Journal web page at http://dx.doi.org/10.1140/epjd/e2015-60583-7

  3. Mainshock-aftershock clustering in volcanic regions

    USGS Publications Warehouse

    Giron, Ricardo Garza; Brodsky, Emily E.; Prejean, Stephanie

    2018-01-01

    swarms and mainshock-aftershock sequences. The former is commonly thought to dominate in volcanic and geothermal regions, but aftershock production, including within swarms, is not well studied in volcanic regions. Here we compare mainshock-aftershock clustering in active volcanic regions in Japan to nearby nonvolcanic regions. We find that aftershock production is similar in both areas by two separate metrics: (1) Both volcanic and nonvolcanic regions have similar proportions of areas that cluster into mainshock-aftershock sequences. (2) Volcanic areas with mainshock-aftershock sequences have aftershock productivity at least as high as nonvolcanic regions. We also find that volcano-tectonic events that are precursors to an eruption are more common at volcanoes without mainshock-aftershock clusters than at volcanoes with well-defined mainshock-aftershock clusters. This last finding hints at a strategy to identify volcanic systems where cataloged earthquakes are good predictors of behavior.

  4. Mainshock-Aftershock Clustering in Volcanic Regions

    NASA Astrophysics Data System (ADS)

    Garza-Giron, Ricardo; Brodsky, Emily E.; Prejean, Stephanie G.

    2018-02-01

    Earthquakes break their general Poissonean behavior through two types of seismic bursts: swarms and mainshock-aftershock sequences. The former is commonly thought to dominate in volcanic and geothermal regions, but aftershock production, including within swarms, is not well studied in volcanic regions. Here we compare mainshock-aftershock clustering in active volcanic regions in Japan to nearby nonvolcanic regions. We find that aftershock production is similar in both areas by two separate metrics: (1) Both volcanic and nonvolcanic regions have similar proportions of areas that cluster into mainshock-aftershock sequences. (2) Volcanic areas with mainshock-aftershock sequences have aftershock productivity at least as high as nonvolcanic regions. We also find that volcano-tectonic events that are precursors to an eruption are more common at volcanoes without mainshock-aftershock clusters than at volcanoes with well-defined mainshock-aftershock clusters. This last finding hints at a strategy to identify volcanic systems where cataloged earthquakes are good predictors of behavior.

  5. A statistical method (cross-validation) for bone loss region detection after spaceflight

    PubMed Central

    Zhao, Qian; Li, Wenjun; Li, Caixia; Chu, Philip W.; Kornak, John; Lang, Thomas F.

    2010-01-01

    Astronauts experience bone loss after the long spaceflight missions. Identifying specific regions that undergo the greatest losses (e.g. the proximal femur) could reveal information about the processes of bone loss in disuse and disease. Methods for detecting such regions, however, remains an open problem. This paper focuses on statistical methods to detect such regions. We perform statistical parametric mapping to get t-maps of changes in images, and propose a new cross-validation method to select an optimum suprathreshold for forming clusters of pixels. Once these candidate clusters are formed, we use permutation testing of longitudinal labels to derive significant changes. PMID:20632144

  6. The mass function and dynamical mass of young star clusters: why their initial crossing-time matters crucially

    NASA Astrophysics Data System (ADS)

    Parmentier, Geneviève; Baumgardt, Holger

    2012-12-01

    We highlight the impact of cluster-mass-dependent evolutionary rates upon the evolution of the cluster mass function during violent relaxation, that is, while clusters dynamically respond to the expulsion of their residual star-forming gas. Mass-dependent evolutionary rates arise when the mean volume density of cluster-forming regions is mass-dependent. In that case, even if the initial conditions are such that the cluster mass function at the end of violent relaxation has the same shape as the embedded-cluster mass function (i.e. infant weight-loss is mass-independent), the shape of the cluster mass function does change transiently during violent relaxation. In contrast, for cluster-forming regions of constant mean volume density, the cluster mass function shape is preserved all through violent relaxation since all clusters then evolve at the same mass-independent rate. On the scale of individual clusters, we model the evolution of the ratio of the dynamical mass to luminous mass of a cluster after gas expulsion. Specifically, we map the radial dependence of the time-scale for a star cluster to return to equilibrium. We stress that fields of view a few pc in size only, typical of compact clusters with rapid evolutionary rates, are likely to reveal cluster regions which have returned to equilibrium even if the cluster experienced a major gas expulsion episode a few Myr earlier. We provide models with the aperture and time expressed in units of the initial half-mass radius and initial crossing-time, respectively, so that our results can be applied to clusters with initial densities, sizes, and apertures different from ours.

  7. The Clusters - Collaborative Models of Sustainable Regional Development

    NASA Astrophysics Data System (ADS)

    Mănescu, Gabriel; Kifor, Claudiu

    2014-12-01

    The clusters are the subject of actions and of whole series of documents issued by national and international organizations, and, based on experience, many authorities promote the idea that because of the clusters, competitiveness increases, the workforce specializes, regional businesses and economies grow. The present paper is meant to be an insight into the initiatives of forming clusters in Romania. Starting from a comprehensive analysis of the development potential offered by each region of economic development, we present the main types of clusters grouped according to fields of activity and their overall objectives

  8. Regional heatwaves in china: a cluster analysis

    NASA Astrophysics Data System (ADS)

    Wang, Pinya; Tang, Jianping; Wang, Shuyu; Dong, Xinning; Fang, Juan

    2018-03-01

    With the consideration of spatial extension of heatwave events, two kind of regional heatwaves using absolute and relative thresholds, namely RHWs-A and RHWs-R, are investigated during 1959-2013. The temperature data is derived from the daily maximum temperatures (DMTs) of 587 stations in China. Totally 298 RHWs-A and 374 RHWs-R are identified during the past 55 years, and both of them are growing more frequent since the mid-1980s. By utilizing the cluster analysis, several typical spatial distributions of RHWs-A/RHWs-R are obtained. For RHWs-A, there are three clusters covering the southeastern, northwestern China and the lower reaches of Yangtze River, of which the southeastern cluster groups the most heatwaves. For RHWs-R, there are seven clusters distributed throughout the whole regions of China. The clusters in the northwestern and northeastern China are more stable than others for both RHWs-A and RHWs-R, and the northern clusters are of larger intensity than that of the southern ones. All RHWs-A/RHWs-R are accompanied by the anomalous high systems along with the reduced soil moisture. The southern clusters are controlled by Northwestern Pacific subtropical high (WPSH), and the northern ones are influenced by the mid-latitude high systems. The influences of atmospheric circulations and soil moisture on regional heatwaves are further demonstrated by two case analyses of the severe RHW-A in 2003 and the RHW-R in 2013.

  9. Cross validation issues in multiobjective clustering

    PubMed Central

    Brusco, Michael J.; Steinley, Douglas

    2018-01-01

    The implementation of multiobjective programming methods in combinatorial data analysis is an emergent area of study with a variety of pragmatic applications in the behavioural sciences. Most notably, multiobjective programming provides a tool for analysts to model trade offs among competing criteria in clustering, seriation, and unidimensional scaling tasks. Although multiobjective programming has considerable promise, the technique can produce numerically appealing results that lack empirical validity. With this issue in mind, the purpose of this paper is to briefly review viable areas of application for multiobjective programming and, more importantly, to outline the importance of cross-validation when using this method in cluster analysis. PMID:19055857

  10. Mainshock-Aftershocks Clustering Detection in Volcanic Regions

    NASA Astrophysics Data System (ADS)

    Garza Giron, R.; Brodsky, E. E.; Prejean, S. G.

    2017-12-01

    Crustal earthquakes tend to break their general Poissonean process behavior by gathering into two main kinds of seismic bursts: swarms and mainshock-aftershocks sequences. The former is commonly related to volcanic or geothermal processes whereas the latter is a characteristic feature of tectonically driven seismicity. We explore the mainshock-aftershock clustering behavior of different active volcanic regions in Japan and its comparison to non-volcanic regions. We find that aftershock production in volcanoes shows mainshock-aftershocks clustering similar to what is observed in non-volcanic areas. The ratio of volanic areas that cluster in mainshock-aftershocks sequences vs the areas that do not is comparable to the ratio of non-volcanic regions that show clustering vs the ones that do not. Furthermore, the level of production of aftershocks for most volcanic areas where clustering is present seems to be of the same order of magnitude, or slightly higher, as the median of the non-volcanic regions. An interesting example of highly aftershock-productive volcanoes emerges from the 2000 Miyakejima dike intrusion. A big seismic cluster started to build up rapidly in the south-west flank of Miyakejima to later propagate to the north-west towards the Kozushima and Niijima volcanoes. In Miyakejima the seismicity showed a swarm-like signature with a constant earthquake rate, whereas Kozushima and Niijima both had expressions of highly productive mainshock-aftershocks sequences. These findings are surprising given the alternative mechanisms available in volcanic systems for releasing deviatoric strain. We speculate that aftershock behavior might hold a relationship with the rheological properties of the rocks of each system and with the capacity of a system to accumulate or release the internal pressures caused by magmatic or hydrothermal systems.

  11. Cluster in the Auroral Acceleration Region

    NASA Technical Reports Server (NTRS)

    Pickett, Jolene S.; Fazakerley, Andrew N.; Marklund, Gorun; Dandouras, Iannis; Christopher, Ivar W.; Kistler, Lynn; Lucek, Elizabeth; Masson, Arnaud; Taylor, Matthew G.; Mutel, Robert L.; hide

    2010-01-01

    Due to a fortuitous evolution of the Cluster orbit, the Cluster spacecraft penetrated for the first time in its mission the heart of Earth's auroral acceleration region (AAR) in December 2009 and January 2010. During this time a special AAR campaign was carried out by the various Cluster instrument teams with special support from ESA and NASA facilities. We present some of the first multi-spacecraft observations of the waves, particles and fields made during that campaign. The Cluster spacecraft configuration during these AAR passages was such that it allowed us to explore the differences in the signatures of waves, particles, and fields on the various spacecraft in ways not possible with single spacecraft. For example, one spacecraft was more poleward than the other three (C2), one was at higher altitude (C1), and one of them (0) followed another (C4) through the AAR on approximately the same track but delayed by three minutes. Their separations were generally on the order of a few thousand km or less and occasionally two of them were lying along the same magnetic field line. We will show some of the first analyses of the data obtained during the AAR campaign, where upward and downward current regions, and the waves specifically associated with those regions, as well as the auroral cavities, were observed similarly and differently on the various spacecraft, helping us to explore the spatial, as well as the temporal, aspects of processes occurring in the AAR.

  12. A Cross-Cultural Comparison of Symptom Reporting and Symptom Clusters in Heart Failure.

    PubMed

    Park, Jumin; Johantgen, Mary E

    2017-07-01

    An understanding of symptoms in heart failure (HF) among different cultural groups has become increasingly important. The purpose of this study was to compare symptom reporting and symptom clusters in HF patients between a Western (the United States) and an Eastern Asian sample (China and Taiwan). A secondary analysis of a cross-sectional observational study was conducted. The data were obtained from a matched HF patient sample from the United States and China/Taiwan ( N = 240 in each). Eight selective items related to HF symptoms from the Minnesota Living with Heart Failure Questionnaire were analyzed. Compared with the U.S. sample, HF patients from China/Taiwan reported a lower level of symptom distress. Analysis of two different regional groups did not result in the same number of clusters using latent class approach: the United States (four classes) and China/Taiwan (three classes). The study demonstrated that symptom reporting and identification of symptom clusters might be influenced by cultural factors.

  13. The Design of Cluster Randomized Trials with Random Cross-Classifications

    ERIC Educational Resources Information Center

    Moerbeek, Mirjam; Safarkhani, Maryam

    2018-01-01

    Data from cluster randomized trials do not always have a pure hierarchical structure. For instance, students are nested within schools that may be crossed by neighborhoods, and soldiers are nested within army units that may be crossed by mental health-care professionals. It is important that the random cross-classification is taken into account…

  14. Parameters of oscillation generation regions in open star cluster models

    NASA Astrophysics Data System (ADS)

    Danilov, V. M.; Putkov, S. I.

    2017-07-01

    We determine the masses and radii of central regions of open star cluster (OCL) models with small or zero entropy production and estimate the masses of oscillation generation regions in clustermodels based on the data of the phase-space coordinates of stars. The radii of such regions are close to the core radii of the OCL models. We develop a new method for estimating the total OCL masses based on the cluster core mass, the cluster and cluster core radii, and radial distribution of stars. This method yields estimates of dynamical masses of Pleiades, Praesepe, and M67, which agree well with the estimates of the total masses of the corresponding clusters based on proper motions and spectroscopic data for cluster stars.We construct the spectra and dispersion curves of the oscillations of the field of azimuthal velocities v φ in OCL models. Weak, low-amplitude unstable oscillations of v φ develop in cluster models near the cluster core boundary, and weak damped oscillations of v φ often develop at frequencies close to the frequencies of more powerful oscillations, which may reduce the non-stationarity degree in OCL models. We determine the number and parameters of such oscillations near the cores boundaries of cluster models. Such oscillations points to the possible role that gradient instability near the core of cluster models plays in the decrease of the mass of the oscillation generation regions and production of entropy in the cores of OCL models with massive extended cores.

  15. Super Star Clusters and H II Regions in Nuclear Rings

    NASA Astrophysics Data System (ADS)

    Filippenko, Alex

    1996-07-01

    We propose to obtain WFPC2 optical broad-band {F547M and F814W} and narrow-band Halpha+ionN2 {F658N} images of nuclear starburst rings in four nearby galaxies for which we already have ultraviolet {F220W} FOC data. Nuclear rings {or ``hot- spot'' regions} in barred spirals are some of the nearest and least obscured starburst regions, and HST images of nuclear rings in several galaxies show that the rings contain large populations of super star clusters similar to those recently discovered in other types of starburst systems. These compact clusters, many having luminosities exceeding that of the R136 cluster in 30 Doradus, represent a violent mode of star formation distinct from that seen in ordinary disk ionH2 regions, and the nuclear rings present us with an opportunity to study large numbers of these extreme clusters in relatively unobscured starburst environments. It has been suggested that super star clusters are present-day versions of young globular clusters. To evaluate this hypothesis, it is important to understand the physical properties and stellar contents of the clusters, but previous HST studies of nuclear ring galaxies have only used single-filter observations. Together with our UV data, new WFPC2 images will enable us to determine the H II region and cluster luminosity functions within nuclear rings, measure cluster radii, derive age and mass estimates for the clusters by comparison with evolutionary synthesis models, and study the structure and evolution of nuclear rings.

  16. Hartree-Fock calculation of the differential photoionization cross sections of small Li clusters

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Galitskiy, S. A.; Artemyev, A. N.; Jänkälä, K.

    2015-01-21

    Cross sections and angular distribution parameters for the single-photon ionization of all electron orbitals of Li{sub 2−8} are systematically computed in a broad interval of the photoelectron kinetic energies for the energetically most stable geometry of each cluster. Calculations of the partial photoelectron continuum waves in clusters are carried out by the single center method within the Hartree-Fock approximation. We study photoionization cross sections per one electron and analyze in some details general trends in the photoionization of inner and outer shells with respect to the size and geometry of a cluster. The present differential cross sections computed for Li{submore » 2} are in a good agreement with the available theoretical data, whereas those computed for Li{sub 3−8} clusters can be considered as theoretical predictions.« less

  17. Scalable Integrated Region-Based Image Retrieval Using IRM and Statistical Clustering.

    ERIC Educational Resources Information Center

    Wang, James Z.; Du, Yanping

    Statistical clustering is critical in designing scalable image retrieval systems. This paper presents a scalable algorithm for indexing and retrieving images based on region segmentation. The method uses statistical clustering on region features and IRM (Integrated Region Matching), a measure developed to evaluate overall similarity between images…

  18. Impact of SZ cluster residuals in CMB maps and CMB-LSS cross-correlations

    NASA Astrophysics Data System (ADS)

    Chen, T.; Remazeilles, M.; Dickinson, C.

    2018-06-01

    Residual foreground contamination in cosmic microwave background (CMB) maps, such as the residual contamination from thermal Sunyaev-Zeldovich (SZ) effect in the direction of galaxy clusters, can bias the cross-correlation measurements between CMB and large-scale structure optical surveys. It is thus essential to quantify those residuals and, if possible, to null out SZ cluster residuals in CMB maps. We quantify for the first time the amount of SZ cluster contamination in the released Planck 2015 CMB maps through (i) the stacking of CMB maps in the direction of the clusters, and (ii) the computation of cross-correlation power spectra between CMB maps and the SDSS-IV large-scale structure data. Our cross-power spectrum analysis yields a 30σ detection at the cluster scale (ℓ = 1500-2500) and a 39σ detection on larger scales (ℓ = 500-1500) due to clustering of SZ clusters, giving an overall 54σ detection of SZ cluster residuals in the Planck CMB maps. The Planck 2015 NILC CMB map is shown to have 44 ± 4% of thermal SZ foreground emission left in it. Using the 'Constrained ILC' component separation technique, we construct an alternative Planck CMB map, the 2D-ILC map, which is shown to have negligible SZ contamination, at the cost of being slightly more contaminated by Galactic foregrounds and noise. We also discuss the impact of the SZ residuals in CMB maps on the measurement of the ISW effect, which is shown to be negligible based on our analysis.

  19. Regional SAR Image Segmentation Based on Fuzzy Clustering with Gamma Mixture Model

    NASA Astrophysics Data System (ADS)

    Li, X. L.; Zhao, Q. H.; Li, Y.

    2017-09-01

    Most of stochastic based fuzzy clustering algorithms are pixel-based, which can not effectively overcome the inherent speckle noise in SAR images. In order to deal with the problem, a regional SAR image segmentation algorithm based on fuzzy clustering with Gamma mixture model is proposed in this paper. First, initialize some generating points randomly on the image, the image domain is divided into many sub-regions using Voronoi tessellation technique. Each sub-region is regarded as a homogeneous area in which the pixels share the same cluster label. Then, assume the probability of the pixel to be a Gamma mixture model with the parameters respecting to the cluster which the pixel belongs to. The negative logarithm of the probability represents the dissimilarity measure between the pixel and the cluster. The regional dissimilarity measure of one sub-region is defined as the sum of the measures of pixels in the region. Furthermore, the Markov Random Field (MRF) model is extended from pixels level to Voronoi sub-regions, and then the regional objective function is established under the framework of fuzzy clustering. The optimal segmentation results can be obtained by the solution of model parameters and generating points. Finally, the effectiveness of the proposed algorithm can be proved by the qualitative and quantitative analysis from the segmentation results of the simulated and real SAR images.

  20. An Empirical Approach to Logical Clustering of Software Failure Regions

    DTIC Science & Technology

    1994-03-01

    this is a coincidence or normal behavior of failure regions. " Software faults were numbered in order as they were discovered, by the various testing...locations of the associated faults. The goal of this research will be an improved testing technique that incorporates failure region behavior . To do this...clustering behavior . This, however, does not correlate with the structural clustering of failure regions observed by Ginn (1991) on the same set of data

  1. Using cluster analysis to organize and explore regional GPS velocities

    USGS Publications Warehouse

    Simpson, Robert W.; Thatcher, Wayne; Savage, James C.

    2012-01-01

    Cluster analysis offers a simple visual exploratory tool for the initial investigation of regional Global Positioning System (GPS) velocity observations, which are providing increasingly precise mappings of actively deforming continental lithosphere. The deformation fields from dense regional GPS networks can often be concisely described in terms of relatively coherent blocks bounded by active faults, although the choice of blocks, their number and size, can be subjective and is often guided by the distribution of known faults. To illustrate our method, we apply cluster analysis to GPS velocities from the San Francisco Bay Region, California, to search for spatially coherent patterns of deformation, including evidence of block-like behavior. The clustering process identifies four robust groupings of velocities that we identify with four crustal blocks. Although the analysis uses no prior geologic information other than the GPS velocities, the cluster/block boundaries track three major faults, both locked and creeping.

  2. The Auroral Field-aligned Acceleration - Cluster Results

    NASA Astrophysics Data System (ADS)

    Vaivads, A.; Cluster Auroral Team

    The four Cluster satellites cross the auroral field lines at altitudes well above most of acceleration region. Thus, the orbit is appropriate for studies of the generator side of this region. We consider the energy transport towards the acceleration region and different mechanisms for generating the potential drop. Using data from Cluster we can also for the first time study the dynamics of the generator on a minute scale. We present data from a few auroral field crossings where Cluster are in conjunction with DMSP satellites. We use electric and magnetic field data to estimate electrostatic po- tential along the satellite orbit, Poynting flux as well as the presence of plasma waves. These we can compare with data from particle and wave instruments on Cluster and on low latitude satellites to try to make a consistent picture of the acceleration region formation in these cases. Preliminary results show close agreement both between in- tegrated potential values at Cluster and electron peak energies at DMSP as well as close agreement between the integrated Poynting flux values at Cluster and the elec- tron energy flux at DMSP. At the end we draw a parallels between auroral electron acceleration and electron acceleration at the magnetopause.

  3. HotRegion: a database of predicted hot spot clusters.

    PubMed

    Cukuroglu, Engin; Gursoy, Attila; Keskin, Ozlem

    2012-01-01

    Hot spots are energetically important residues at protein interfaces and they are not randomly distributed across the interface but rather clustered. These clustered hot spots form hot regions. Hot regions are important for the stability of protein complexes, as well as providing specificity to binding sites. We propose a database called HotRegion, which provides the hot region information of the interfaces by using predicted hot spot residues, and structural properties of these interface residues such as pair potentials of interface residues, accessible surface area (ASA) and relative ASA values of interface residues of both monomer and complex forms of proteins. Also, the 3D visualization of the interface and interactions among hot spot residues are provided. HotRegion is accessible at http://prism.ccbb.ku.edu.tr/hotregion.

  4. Cross-correlating the γ-ray Sky with Catalogs of Galaxy Clusters

    NASA Astrophysics Data System (ADS)

    Branchini, Enzo; Camera, Stefano; Cuoco, Alessandro; Fornengo, Nicolao; Regis, Marco; Viel, Matteo; Xia, Jun-Qing

    2017-01-01

    We report the detection of a cross-correlation signal between Fermi Large Area Telescope diffuse γ-ray maps and catalogs of clusters. In our analysis, we considered three different catalogs: WHL12, redMaPPer, and PlanckSZ. They all show a positive correlation with different amplitudes, related to the average mass of the objects in each catalog, which also sets the catalog bias. The signal detection is confirmed by the results of a stacking analysis. The cross-correlation signal extends to rather large angular scales, around 1°, that correspond, at the typical redshift of the clusters in these catalogs, to a few to tens of megaparsecs, I.e., the typical scale-length of the large-scale structures in the universe. Most likely this signal is contributed by the cumulative emission from active galactic nuclei (AGNs) associated with the filamentary structures that converge toward the high peaks of the matter density field in which galaxy clusters reside. In addition, our analysis reveals the presence of a second component, more compact in size and compatible with a point-like emission from within individual clusters. At present, we cannot distinguish between the two most likely interpretations for such a signal, I.e., whether it is produced by AGNs inside clusters or if it is a diffuse γ-ray emission from the intracluster medium. We argue that this latter, intriguing, hypothesis might be tested by applying this technique to a low-redshift large-mass cluster sample.

  5. 75 FR 17700 - Energy Efficient Building Systems Regional Innovation Cluster Initiative-Joint Federal Funding...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-07

    ... economically dynamic regional innovation cluster focused on energy efficient buildings technologies and systems... DEPARTMENT OF ENERGY Energy Efficient Building Systems Regional Innovation Cluster Initiative... February 8, 2010, titled the Energy Efficient Building Systems Regional Innovation Cluster Initiative. A...

  6. A coupled-cluster study of photodetachment cross sections of closed-shell anions

    NASA Astrophysics Data System (ADS)

    Cukras, Janusz; Decleva, Piero; Coriani, Sonia

    2014-11-01

    We investigate the performance of Stieltjes Imaging applied to Lanczos pseudo-spectra generated at the coupled cluster singles and doubles, coupled cluster singles and approximate iterative doubles and coupled cluster singles levels of theory in modeling the photodetachment cross sections of the closed shell anions H-, Li-, Na-, F-, Cl-, and OH-. The accurate description of double excitations is found to play a much more important role than in the case of photoionization of neutral species.

  7. A coupled-cluster study of photodetachment cross sections of closed-shell anions.

    PubMed

    Cukras, Janusz; Decleva, Piero; Coriani, Sonia

    2014-11-07

    We investigate the performance of Stieltjes Imaging applied to Lanczos pseudo-spectra generated at the coupled cluster singles and doubles, coupled cluster singles and approximate iterative doubles and coupled cluster singles levels of theory in modeling the photodetachment cross sections of the closed shell anions H(-), Li(-), Na(-), F(-), Cl(-), and OH(-). The accurate description of double excitations is found to play a much more important role than in the case of photoionization of neutral species.

  8. CROSS-CORRELATING THE γ-RAY SKY WITH CATALOGS OF GALAXY CLUSTERS

    DOE PAGES

    Branchini, Enzo; Camera, Stefano; Cuoco, Alessandro; ...

    2017-01-18

    In this article, we report the detection of a cross-correlation signal between Fermi Large Area Telescope diffuse γ-ray maps and catalogs of clusters. In our analysis, we considered three different catalogs: WHL12, redMaPPer, and PlanckSZ. They all show a positive correlation with different amplitudes, related to the average mass of the objects in each catalog, which also sets the catalog bias. The signal detection is confirmed by the results of a stacking analysis. The cross-correlation signal extends to rather large angular scales, around 1°, that correspond, at the typical redshift of the clusters in these catalogs, to a few tomore » tens of megaparsecs, i.e., the typical scale-length of the large-scale structures in the universe. Most likely this signal is contributed by the cumulative emission from active galactic nuclei (AGNs) associated with the filamentary structures that converge toward the high peaks of the matter density field in which galaxy clusters reside. In addition, our analysis reveals the presence of a second component, more compact in size and compatible with a point-like emission from within individual clusters. At present, we cannot distinguish between the two most likely interpretations for such a signal, i.e., whether it is produced by AGNs inside clusters or if it is a diffuse γ-ray emission from the intracluster medium. Lastly, we argue that this latter, intriguing, hypothesis might be tested by applying this technique to a low-redshift large-mass cluster sample.« less

  9. Effect of Rubber Polarity on Cluster Formation in Rubbers Cross-Linked with Diels–Alder Chemistry

    PubMed Central

    2017-01-01

    Diels–Alder chemistry has been used for the thermoreversible cross-linking of furan-functionalized ethylene/propylene (EPM) and ethylene/vinyl acetate (EVM) rubbers. Both furan-functionalized elastomers were successfully cross-linked with bismaleimide to yield products with a similar cross-link density. NMR relaxometry and SAXS measurements both show that the apolar EPM-g-furan precursor contains phase-separated polar clusters and that cross-linking with polar bismaleimide occurs in these clusters. The heterogeneously cross-linked network of EPM-g-furan contrasts with the homogeneous network in the polar EVM-g-furan. The heterogeneous character of the cross-links in EPM-g-furan results in a relatively high Young’s modulus, whereas the more uniform cross-linking in EVM-g-furan results in a higher tensile strength and elongation at break. PMID:29213149

  10. Sonority and Cross-Linguistic Acquisition of Initial S-Clusters

    ERIC Educational Resources Information Center

    Yavas, Mehmet; Ben-David, Avivit; Gerrits, Ellen; Kristoffersen, Kristian E.; Simonsen, Hanne G.

    2008-01-01

    This paper examines the findings and implications of the cross-linguistic acquisition of #sC clusters in relation to sonority patterns. Data from individual studies on English, Dutch, Norwegian, and Hebrew are compared for accuracy of production as well as the reductions with respect to potential differences across subtypes of #sC groups. In all…

  11. A modified procedure for mixture-model clustering of regional geochemical data

    USGS Publications Warehouse

    Ellefsen, Karl J.; Smith, David B.; Horton, John D.

    2014-01-01

    A modified procedure is proposed for mixture-model clustering of regional-scale geochemical data. The key modification is the robust principal component transformation of the isometric log-ratio transforms of the element concentrations. This principal component transformation and the associated dimension reduction are applied before the data are clustered. The principal advantage of this modification is that it significantly improves the stability of the clustering. The principal disadvantage is that it requires subjective selection of the number of clusters and the number of principal components. To evaluate the efficacy of this modified procedure, it is applied to soil geochemical data that comprise 959 samples from the state of Colorado (USA) for which the concentrations of 44 elements are measured. The distributions of element concentrations that are derived from the mixture model and from the field samples are similar, indicating that the mixture model is a suitable representation of the transformed geochemical data. Each cluster and the associated distributions of the element concentrations are related to specific geologic and anthropogenic features. In this way, mixture model clustering facilitates interpretation of the regional geochemical data.

  12. The smart cluster method. Adaptive earthquake cluster identification and analysis in strong seismic regions

    NASA Astrophysics Data System (ADS)

    Schaefer, Andreas M.; Daniell, James E.; Wenzel, Friedemann

    2017-07-01

    Earthquake clustering is an essential part of almost any statistical analysis of spatial and temporal properties of seismic activity. The nature of earthquake clusters and subsequent declustering of earthquake catalogues plays a crucial role in determining the magnitude-dependent earthquake return period and its respective spatial variation for probabilistic seismic hazard assessment. This study introduces the Smart Cluster Method (SCM), a new methodology to identify earthquake clusters, which uses an adaptive point process for spatio-temporal cluster identification. It utilises the magnitude-dependent spatio-temporal earthquake density to adjust the search properties, subsequently analyses the identified clusters to determine directional variation and adjusts its search space with respect to directional properties. In the case of rapid subsequent ruptures like the 1992 Landers sequence or the 2010-2011 Darfield-Christchurch sequence, a reclassification procedure is applied to disassemble subsequent ruptures using near-field searches, nearest neighbour classification and temporal splitting. The method is capable of identifying and classifying earthquake clusters in space and time. It has been tested and validated using earthquake data from California and New Zealand. A total of more than 1500 clusters have been found in both regions since 1980 with M m i n = 2.0. Utilising the knowledge of cluster classification, the method has been adjusted to provide an earthquake declustering algorithm, which has been compared to existing methods. Its performance is comparable to established methodologies. The analysis of earthquake clustering statistics lead to various new and updated correlation functions, e.g. for ratios between mainshock and strongest aftershock and general aftershock activity metrics.

  13. Shape Analysis of HII Regions - I. Statistical Clustering

    NASA Astrophysics Data System (ADS)

    Campbell-White, Justyn; Froebrich, Dirk; Kume, Alfred

    2018-04-01

    We present here our shape analysis method for a sample of 76 Galactic HII regions from MAGPIS 1.4 GHz data. The main goal is to determine whether physical properties and initial conditions of massive star cluster formation is linked to the shape of the regions. We outline a systematic procedure for extracting region shapes and perform hierarchical clustering on the shape data. We identified six groups that categorise HII regions by common morphologies. We confirmed the validity of these groupings by bootstrap re-sampling and the ordinance technique multidimensional scaling. We then investigated associations between physical parameters and the assigned groups. Location is mostly independent of group, with a small preference for regions of similar longitudes to share common morphologies. The shapes are homogeneously distributed across Galactocentric distance and latitude. One group contains regions that are all younger than 0.5 Myr and ionised by low- to intermediate-mass sources. Those in another group are all driven by intermediate- to high-mass sources. One group was distinctly separated from the other five and contained regions at the surface brightness detection limit for the survey. We find that our hierarchical procedure is most sensitive to the spatial sampling resolution used, which is determined for each region from its distance. We discuss how these errors can be further quantified and reduced in future work by utilising synthetic observations from numerical simulations of HII regions. We also outline how this shape analysis has further applications to other diffuse astronomical objects.

  14. Hierarchical Regional Disparities and Potential Sector Identification Using Modified Agglomerative Clustering

    NASA Astrophysics Data System (ADS)

    Munandar, T. A.; Azhari; Mushdholifah, A.; Arsyad, L.

    2017-03-01

    Disparities in regional development methods are commonly identified using the Klassen Typology and Location Quotient. Both methods typically use the data on the gross regional domestic product (GRDP) sectors of a particular region. The Klassen approach can identify regional disparities by classifying the GRDP sector data into four classes, namely Quadrants I, II, III, and IV. Each quadrant indicates a certain level of regional disparities based on the GRDP sector value of the said region. Meanwhile, the Location Quotient (LQ) is usually used to identify potential sectors in a particular region so as to determine which sectors are potential and which ones are not potential. LQ classifies each sector into three classes namely, the basic sector, the non-basic sector with a competitive advantage, and the non-basic sector which can only meet its own necessities. Both Klassen Typology and LQ are unable to visualize the relationship of achievements in the development clearly of each region and sector. This research aimed to develop a new approach to the identification of disparities in regional development in the form of hierarchical clustering. The method of Hierarchical Agglomerative Clustering (HAC) was employed as the basis of the hierarchical clustering model for identifying disparities in regional development. Modifications were made to HAC using the Klassen Typology and LQ. Then, HAC which had been modified using the Klassen Typology was called MHACK while HAC which had been modified using LQ was called MACLoQ. Both algorithms can be used to identify regional disparities (MHACK) and potential sectors (MACLoQ), respectively, in the form of hierarchical clusters. Based on the MHACK in 31 regencies in Central Java Province, it is identified that 3 regencies (Demak, Jepara, and Magelang City) fall into the category of developed and rapidly-growing regions, while the other 28 regencies fall into the category of developed but depressed regions. Results of the MACLo

  15. Uptake of methanol on mixed HNO3/H2O clusters: An absolute pickup cross section

    NASA Astrophysics Data System (ADS)

    Pysanenko, A.; Lengyel, J.; Fárník, M.

    2018-04-01

    The uptake of atmospheric oxidized organics on acid clusters is relevant for atmospheric new particle formation. We investigate the pickup of methanol (CH3OH) on mixed nitric acid-water clusters (HNO3)M(H2O)N by a combination of mass spectrometry and cluster velocity measurements in a molecular beam. The mass spectra of the mixed clusters exhibit (HNO3)m(H2O)nH+ series with m = 0-3 and n = 0-12. In addition, CH3OH.(HNO3)m(H2O)nH+ series with very similar patterns appear in the spectra after the methanol pickup. The velocity measurements prove that the undoped (HNO3)m(H2O)nH+ mass peaks in the pickup spectra originate from the neutral (HNO3)M(H2O)N clusters which have not picked up any CH3OH molecule, i.e., methanol has not evaporated upon the ionization. Thus the fraction of the doped clusters can be determined and the mean pickup cross section can be estimated, yielding σs ¯ ≈ 20 Å2. This is compared to the lower estimate of the mean geometrical cross section σg ¯ ≈ 60 Å2 obtained from the theoretical cluster geometries. Thus the "size" of the cluster corresponding to the methanol pickup is at least 3-times smaller than its geometrical size. We have introduced a method which can yield the absolute pickup cross sections relevant to the generation and growth of atmospheric aerosols, as illustrated in the example of methanol and nitric acid clusters.

  16. Scale size and life time of energy conversion regions observed by Cluster in the plasma sheet

    NASA Astrophysics Data System (ADS)

    Hamrin, M.; Norqvist, P.; Marghitu, O.; Vaivads, A.; Klecker, B.; Kistler, L. M.; Dandouras, I.

    2009-11-01

    In this article, and in a companion paper by Hamrin et al. (2009) [Occurrence and location of concentrated load and generator regions observed by Cluster in the plasma sheet], we investigate localized energy conversion regions (ECRs) in Earth's plasma sheet. From more than 80 Cluster plasma sheet crossings (660 h data) at the altitude of about 15-20 RE in the summer and fall of 2001, we have identified 116 Concentrated Load Regions (CLRs) and 35 Concentrated Generator Regions (CGRs). By examining variations in the power density, E·J, where E is the electric field and J is the current density obtained by Cluster, we have estimated typical values of the scale size and life time of the CLRs and the CGRs. We find that a majority of the observed ECRs are rather stationary in space, but varying in time. Assuming that the ECRs are cylindrically shaped and equal in size, we conclude that the typical scale size of the ECRs is 2 RE≲ΔSECR≲5 RE. The ECRs hence occupy a significant portion of the mid altitude plasma sheet. Moreover, the CLRs appear to be somewhat larger than the CGRs. The life time of the ECRs are of the order of 1-10 min, consistent with the large scale magnetotail MHD simulations of Birn and Hesse (2005). The life time of the CGRs is somewhat shorter than for the CLRs. On time scales of 1-10 min, we believe that ECRs rise and vanish in significant regions of the plasma sheet, possibly oscillating between load and generator character. It is probable that at least some of the observed ECRs oscillate energy back and forth in the plasma sheet instead of channeling it to the ionosphere.

  17. Temporal Clustering of Regional-Scale Extreme Precipitation Events in Southern Switzerland

    NASA Astrophysics Data System (ADS)

    Barton, Yannick; Giannakaki, Paraskevi; Von Waldow, Harald; Chevalier, Clément; Pfhal, Stephan; Martius, Olivia

    2017-04-01

    Temporal clustering of extreme precipitation events on subseasonal time scales is a form of compound extremes and is of crucial importance for the formation of large-scale flood events. Here, the temporal clustering of regional-scale extreme precipitation events in southern Switzerland is studied. These precipitation events are relevant for the flooding of lakes in southern Switzerland and northern Italy. This research determines whether temporal clustering is present and then identifies the dynamics that are responsible for the clustering. An observation-based gridded precipitation dataset of Swiss daily rainfall sums and ECMWF reanalysis datasets are used. To analyze the clustering in the precipitation time series a modified version of Ripley's K function is used. It determines the average number of extreme events in a time period, to characterize temporal clustering on subseasonal time scales and to determine the statistical significance of the clustering. Significant clustering of regional-scale precipitation extremes is found on subseasonal time scales during the fall season. Four high-impact clustering episodes are then selected and the dynamics responsible for the clustering are examined. During the four clustering episodes, all heavy precipitation events were associated with an upperlevel breaking Rossby wave over western Europe and in most cases strong diabatic processes upstream over the Atlantic played a role in the amplification of these breaking waves. Atmospheric blocking downstream over eastern Europe supported this wave breaking during two of the clustering episodes. During one of the clustering periods, several extratropical transitions of tropical cyclones in the Atlantic contributed to the formation of high-amplitude ridges over the Atlantic basin and downstream wave breaking. During another event, blocking over Alaska assisted the phase locking of the Rossby waves downstream over the Atlantic.

  18. Improving hot region prediction by parameter optimization of density clustering in PPI.

    PubMed

    Hu, Jing; Zhang, Xiaolong

    2016-11-01

    This paper proposed an optimized algorithm which combines density clustering of parameter selection with feature-based classification for hot region prediction. First, all the residues are classified by SVM to remove non-hot spot residues, then density clustering of parameter selection is used to find hot regions. In the density clustering, this paper studies how to select input parameters. There are two parameters radius and density in density-based incremental clustering. We firstly fix density and enumerate radius to find a pair of parameters which leads to maximum number of clusters, and then we fix radius and enumerate density to find another pair of parameters which leads to maximum number of clusters. Experiment results show that the proposed method using both two pairs of parameters provides better prediction performance than the other method, and compare these two predictive results, the result by fixing radius and enumerating density have slightly higher prediction accuracy than that by fixing density and enumerating radius. Copyright © 2016. Published by Elsevier Inc.

  19. The Gas Distribution in Galaxy Cluster Outer Regions

    NASA Technical Reports Server (NTRS)

    Eckert, D.; Vazza, F.; Ettori, S.; Molendi, S.; Nagai, D.; Laue, E. T.; Roncarelli, M.; Rossetti, M.; Snowden, S. L.; Gastaldello, F.

    2012-01-01

    Aims. We present the analysis of a local (z = 0.04 - 0.2) sample of 31 galaxy clusters with the aim of measuring the density of the X-ray emitting gas in cluster outskirts. We compare our results with numerical simulations to set constraints on the azimuthal symmetry and gas clumping in the outer regions of galaxy clusters. Methods. We exploit the large field-of-view and low instrumental background of ROSAT/PSPC to trace the density of the intracluster gas out to the virial radius. We perform a stacking of the density profiles to detect a signal beyond r200 and measure the typical density and scatter in cluster outskirts. We also compute the azimuthal scatter of the profiles with respect to the mean value to look for deviations from spherical symmetry. Finally, we compare our average density and scatter profiles with the results of numerical simulations. Results. As opposed to some recent Suzaku results, and confirming previous evidence from ROSAT and Chandra, we observe a steepening of the density profiles beyond approximately r(sub 500). Comparing our density profiles with simulations, we find that non-radiative runs predict too steep density profiles, whereas runs including additional physics and/or treating gas clumping are in better agreement with the observed gas distribution. We report for the first time the high-confidence detection of a systematic difference between cool-core and non-cool core clusters beyond 0.3r(sub 200), which we explain by a different distribution of the gas in the two classes. Beyond r(sub 500), galaxy clusters deviate significantly from spherical symmetry, with only little differences between relaxed and disturbed systems. We find good agreement between the observed and predicted scatter profiles, but only when the 1% densest clumps are filtered out in the simulations. Conclusions. Comparing our results with numerical simulations, we find that non-radiative simulations fail to reproduce the gas distribution, even well outside cluster

  20. INTER- AND INTRA-CLUSTER AGE GRADIENTS IN MASSIVE STAR FORMING REGIONS AND INDIVIDUAL NEARBY STELLAR CLUSTERS REVEALED BY MYStIX

    NASA Astrophysics Data System (ADS)

    Getman, Konstantin V.; Feigelson, Eric; Kuhn, Michael A.; Broos, Patrick S; Townsley, Leisa K.; Naylor, Tim; Povich, Matthew S.; Luhman, Kevin; Garmire, Gordon

    2014-08-01

    The MYStIX (Massive Young Star-Forming Complex Study in Infrared and X-ray) project seeks to characterize 20 OB-dominated young star forming regions (SFRs) at distances <4 kpc using photometric catalogs from the Chandra X-ray Observatory, Spitzer Space Telescope, UKIRT and 2MASS surveys. As part of the MYStIX project, we developed a new stellar chronometer that employs near-infrared and X-ray photometry data, AgeJX. Computing AgeJX averaged over MYStIX (sub)clusters reveals previously unknown age gradients across most of the MYStIX regions as well as within some individual rich clusters. Within the SFRs, the inferred AgeJX ages are youngest in obscured locations in molecular clouds, intermediate in revealed stellar clusters, and oldest in distributed stellar populations. Noticeable intra-cluster gradients are seen in the NGC 2024 (Flame Nebula) star cluster and the Orion Nebula Cluster (ONC): stars in cluster cores appear younger and thus were formed later than stars in cluster halos. The latter result has two important implications for the formation of young stellar clusters. Clusters likely form slowly: they do not arise from a single nearly-instantaneous burst of star formation. The simple models where clusters form inside-out are likely incorrect, and more complex models are needed. We provide several star formation scenarios that alone or in combination may lead to the observed core-halo age gradients.

  1. Observational and Numerical Diagnostics of Galaxy Cluster Outer Regions

    NASA Technical Reports Server (NTRS)

    Eckert, D.; Vazza, F.; Ettori, S.; Molendi, S.; Nagai, D.; Lau, E.; Roncarelli, M.; Rossetti, M.; Snowden, S. L.; Gastaldello, F.

    2011-01-01

    Aims. We present the analysis of a local (z = 0.04 - 0.2) sample of 31 galaxy clusters with the aim of measuring the density of the X-ray emitting gas in cluster outskirts. We compare our results with numerical simulations to set constraints on the azimuthal symmetry and gas clumping in the outer regions of galaxy clusters. Methods. We exploit the large field-of-view and low instrumental background of ROSAT/PSPC to trace the density of the intracluster gas out to the virial radius. We perform a stacking of the density profiles to detect a signal beyond r(sub 200) and measure the typical density and scatter in cluster outskirts. We also compute the azimuthal scatter of the profiles with respect to the mean value to look for deviations from spherical symmetry. Finally, we compare our average density and scatter profiles with the results of numerical simulations. Results. As opposed to several recent results, we observe a steepening of the density profiles beyond approximately 0.3r(sub 500). Comparing our density profiles with simulations, we find that non-radiative runs predict too steep density profiles, whereas runs including additional physics and/or gas clumping are in better agreement with the observed gas distribution. We note a systematic difference between cool-core and non-cool core clusters beyond approximately 0.3r(sub 200), which we explain by a different distribution of the gas in the two classes. Beyond approximately r(sub 500), galaxy clusters deviate significantly from spherical symmetry, with only little differences between relaxed and disturbed systems. We find good agreement between the observed and predicted scatter profiles, but only when the 1% densest clumps are filtered out in the simulations. Conclusions. The general trend of steepening density around the virial radius indicates that the shallow density profiles found in several recent works were probably obtained along particular directions (e.g., filaments) and are not representative of the

  2. Recursive Hierarchical Image Segmentation by Region Growing and Constrained Spectral Clustering

    NASA Technical Reports Server (NTRS)

    Tilton, James C.

    2002-01-01

    This paper describes an algorithm for hierarchical image segmentation (referred to as HSEG) and its recursive formulation (referred to as RHSEG). The HSEG algorithm is a hybrid of region growing and constrained spectral clustering that produces a hierarchical set of image segmentations based on detected convergence points. In the main, HSEG employs the hierarchical stepwise optimization (HS WO) approach to region growing, which seeks to produce segmentations that are more optimized than those produced by more classic approaches to region growing. In addition, HSEG optionally interjects between HSWO region growing iterations merges between spatially non-adjacent regions (i.e., spectrally based merging or clustering) constrained by a threshold derived from the previous HSWO region growing iteration. While the addition of constrained spectral clustering improves the segmentation results, especially for larger images, it also significantly increases HSEG's computational requirements. To counteract this, a computationally efficient recursive, divide-and-conquer, implementation of HSEG (RHSEG) has been devised and is described herein. Included in this description is special code that is required to avoid processing artifacts caused by RHSEG s recursive subdivision of the image data. Implementations for single processor and for multiple processor computer systems are described. Results with Landsat TM data are included comparing HSEG with classic region growing. Finally, an application to image information mining and knowledge discovery is discussed.

  3. Dynamic cluster generation for a fuzzy classifier with ellipsoidal regions.

    PubMed

    Abe, S

    1998-01-01

    In this paper, we discuss a fuzzy classifier with ellipsoidal regions that dynamically generates clusters. First, for the data belonging to a class we define a fuzzy rule with an ellipsoidal region. Namely, using the training data for each class, we calculate the center and the covariance matrix of the ellipsoidal region for the class. Then we tune the fuzzy rules, i.e., the slopes of the membership functions, successively until there is no improvement in the recognition rate of the training data. Then if the number of the data belonging to a class that are misclassified into another class exceeds a prescribed number, we define a new cluster to which those data belong and the associated fuzzy rule. Then we tune the newly defined fuzzy rules in the similar way as stated above, fixing the already obtained fuzzy rules. We iterate generation of clusters and tuning of the newly generated fuzzy rules until the number of the data belonging to a class that are misclassified into another class does not exceed the prescribed number. We evaluate our method using thyroid data, Japanese Hiragana data of vehicle license plates, and blood cell data. By dynamic cluster generation, the generalization ability of the classifier is improved and the recognition rate of the fuzzy classifier for the test data is the best among the neural network classifiers and other fuzzy classifiers if there are no discrete input variables.

  4. 75 FR 7464 - Energy Efficient Building Systems Regional Innovation Cluster Initiative-Joint Federal Funding...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-19

    ... DEPARTMENT OF ENERGY Energy Efficient Building Systems Regional Innovation Cluster Initiative... Energy Efficient Building Systems Regional Innovation Cluster Initiative. A single proposal submitted by... systems design. The DOE funded Energy Efficient Building Systems Design Hub (the ``Hub'') will serve as a...

  5. Photoionization cross section by Stieltjes imaging applied to coupled cluster Lanczos pseudo-spectra

    NASA Astrophysics Data System (ADS)

    Cukras, Janusz; Coriani, Sonia; Decleva, Piero; Christiansen, Ove; Norman, Patrick

    2013-09-01

    A recently implemented asymmetric Lanczos algorithm for computing (complex) linear response functions within the coupled cluster singles (CCS), coupled cluster singles and iterative approximate doubles (CC2), and coupled cluster singles and doubles (CCSD) is coupled to a Stieltjes imaging technique in order to describe the photoionization cross section of atoms and molecules, in the spirit of a similar procedure recently proposed by Averbukh and co-workers within the Algebraic Diagrammatic Construction approach. Pilot results are reported for the atoms He, Ne, and Ar and for the molecules H2, H2O, NH3, HF, CO, and CO2.

  6. Photoionization cross section by Stieltjes imaging applied to coupled cluster Lanczos pseudo-spectra.

    PubMed

    Cukras, Janusz; Coriani, Sonia; Decleva, Piero; Christiansen, Ove; Norman, Patrick

    2013-09-07

    A recently implemented asymmetric Lanczos algorithm for computing (complex) linear response functions within the coupled cluster singles (CCS), coupled cluster singles and iterative approximate doubles (CC2), and coupled cluster singles and doubles (CCSD) is coupled to a Stieltjes imaging technique in order to describe the photoionization cross section of atoms and molecules, in the spirit of a similar procedure recently proposed by Averbukh and co-workers within the Algebraic Diagrammatic Construction approach. Pilot results are reported for the atoms He, Ne, and Ar and for the molecules H2, H2O, NH3, HF, CO, and CO2.

  7. Shape analysis of H II regions - I. Statistical clustering

    NASA Astrophysics Data System (ADS)

    Campbell-White, Justyn; Froebrich, Dirk; Kume, Alfred

    2018-07-01

    We present here our shape analysis method for a sample of 76 Galactic H II regions from MAGPIS 1.4 GHz data. The main goal is to determine whether physical properties and initial conditions of massive star cluster formation are linked to the shape of the regions. We outline a systematic procedure for extracting region shapes and perform hierarchical clustering on the shape data. We identified six groups that categorize H II regions by common morphologies. We confirmed the validity of these groupings by bootstrap re-sampling and the ordinance technique multidimensional scaling. We then investigated associations between physical parameters and the assigned groups. Location is mostly independent of group, with a small preference for regions of similar longitudes to share common morphologies. The shapes are homogeneously distributed across Galactocentric distance and latitude. One group contains regions that are all younger than 0.5 Myr and ionized by low- to intermediate-mass sources. Those in another group are all driven by intermediate- to high-mass sources. One group was distinctly separated from the other five and contained regions at the surface brightness detection limit for the survey. We find that our hierarchical procedure is most sensitive to the spatial sampling resolution used, which is determined for each region from its distance. We discuss how these errors can be further quantified and reduced in future work by utilizing synthetic observations from numerical simulations of H II regions. We also outline how this shape analysis has further applications to other diffuse astronomical objects.

  8. Baseline adjustments for binary data in repeated cross-sectional cluster randomized trials.

    PubMed

    Nixon, R M; Thompson, S G

    2003-09-15

    Analysis of covariance models, which adjust for a baseline covariate, are often used to compare treatment groups in a controlled trial in which individuals are randomized. Such analysis adjusts for any baseline imbalance and usually increases the precision of the treatment effect estimate. We assess the value of such adjustments in the context of a cluster randomized trial with repeated cross-sectional design and a binary outcome. In such a design, a new sample of individuals is taken from the clusters at each measurement occasion, so that baseline adjustment has to be at the cluster level. Logistic regression models are used to analyse the data, with cluster level random effects to allow for different outcome probabilities in each cluster. We compare the estimated treatment effect and its precision in models that incorporate a covariate measuring the cluster level probabilities at baseline and those that do not. In two data sets, taken from a cluster randomized trial in the treatment of menorrhagia, the value of baseline adjustment is only evident when the number of subjects per cluster is large. We assess the generalizability of these findings by undertaking a simulation study, and find that increased precision of the treatment effect requires both large cluster sizes and substantial heterogeneity between clusters at baseline, but baseline imbalance arising by chance in a randomized study can always be effectively adjusted for. Copyright 2003 John Wiley & Sons, Ltd.

  9. Functional analysis of the upstream regulatory region of chicken miR-17-92 cluster.

    PubMed

    Cheng, Min; Zhang, Wen-jian; Xing, Tian-yu; Yan, Xiao-hong; Li, Yu-mao; Li, Hui; Wang, Ning

    2016-08-01

    miR-17-92 cluster plays important roles in cell proliferation, differentiation, apoptosis, animal development and tumorigenesis. The transcriptional regulation of miR-17-92 cluster has been extensively studied in mammals, but not in birds. To date, avian miR-17-92 cluster genomic structure has not been fully determined. The promoter location and sequence of miR-17-92 cluster have not been determined, due to the existence of a genomic gap sequence upstream of miR-17-92 cluster in all the birds whose genomes have been sequenced. In this study, genome walking was used to close the genomic gap upstream of chicken miR-17-92 cluster. In addition, bioinformatics analysis, reporter gene assay and truncation mutagenesis were used to investigate functional role of the genomic gap sequence. Genome walking analysis showed that the gap region was 1704 bp long, and its GC content was 80.11%. Bioinformatics analysis showed that in the gap region, there was a 200 bp conserved sequence among the tested 10 species (Gallus gallus, Homo sapiens, Pan troglodytes, Bos taurus, Sus scrofa, Rattus norvegicus, Mus musculus, Possum, Danio rerio, Rana nigromaculata), which is core promoter region of mammalian miR-17-92 host gene (MIR17HG). Promoter luciferase reporter gene vector of the gap region was constructed and reporter assay was performed. The result showed that the promoter activity of pGL3-cMIR17HG (-4228/-2506) was 417 times than that of negative control (empty pGL3 basic vector), suggesting that chicken miR-17-92 cluster promoter exists in the gap region. To further gain insight into the promoter structure, two different truncations for the cloned gap sequence were generated by PCR. One had a truncation of 448 bp at the 5'-end and the other had a truncation of 894 bp at the 3'-end. Further reporter analysis showed that compared with the promoter activity of pGL3-cMIR17HG (-4228/-2506), the reporter activities of the 5'-end truncation and the 3'-end truncation were reduced by 19

  10. Dynamic Trajectory Extraction from Stereo Vision Using Fuzzy Clustering

    NASA Astrophysics Data System (ADS)

    Onishi, Masaki; Yoda, Ikushi

    In recent years, many human tracking researches have been proposed in order to analyze human dynamic trajectory. These researches are general technology applicable to various fields, such as customer purchase analysis in a shopping environment and safety control in a (railroad) crossing. In this paper, we present a new approach for tracking human positions by stereo image. We use the framework of two-stepped clustering with k-means method and fuzzy clustering to detect human regions. In the initial clustering, k-means method makes middle clusters from objective features extracted by stereo vision at high speed. In the last clustering, c-means fuzzy method cluster middle clusters based on attributes into human regions. Our proposed method can be correctly clustered by expressing ambiguity using fuzzy clustering, even when many people are close to each other. The validity of our technique was evaluated with the experiment of trajectories extraction of doctors and nurses in an emergency room of a hospital.

  11. A complete, multi-level conformational clustering of antibody complementarity-determining regions

    PubMed Central

    Nikoloudis, Dimitris; Pitts, Jim E.

    2014-01-01

    Classification of antibody complementarity-determining region (CDR) conformations is an important step that drives antibody modelling and engineering, prediction from sequence, directed mutagenesis and induced-fit studies, and allows inferences on sequence-to-structure relations. Most of the previous work performed conformational clustering on a reduced set of structures or after application of various structure pre-filtering criteria. In this study, it was judged that a clustering of every available CDR conformation would produce a complete and redundant repertoire, increase the number of sequence examples and allow better decisions on structure validity in the future. In order to cope with the potential increase in data noise, a first-level statistical clustering was performed using structure superposition Root-Mean-Square Deviation (RMSD) as a distance-criterion, coupled with second- and third-level clustering that employed Ramachandran regions for a deeper qualitative classification. The classification of a total of 12,712 CDR conformations is thus presented, along with rich annotation and cluster descriptions, and the results are compared to previous major studies. The present repertoire has procured an improved image of our current CDR Knowledge-Base, with a novel nesting of conformational sensitivity and specificity that can serve as a systematic framework for improved prediction from sequence as well as a number of future studies that would aid in knowledge-based antibody engineering such as humanisation. PMID:25071986

  12. Deconstructing Bipolar Disorder and Schizophrenia: A cross-diagnostic cluster analysis of cognitive phenotypes.

    PubMed

    Lee, Junghee; Rizzo, Shemra; Altshuler, Lori; Glahn, David C; Miklowitz, David J; Sugar, Catherine A; Wynn, Jonathan K; Green, Michael F

    2017-02-01

    Bipolar disorder (BD) and schizophrenia (SZ) show substantial overlap. It has been suggested that a subgroup of patients might contribute to these overlapping features. This study employed a cross-diagnostic cluster analysis to identify subgroups of individuals with shared cognitive phenotypes. 143 participants (68 BD patients, 39 SZ patients and 36 healthy controls) completed a battery of EEG and performance assessments on perception, nonsocial cognition and social cognition. A K-means cluster analysis was conducted with all participants across diagnostic groups. Clinical symptoms, functional capacity, and functional outcome were assessed in patients. A two-cluster solution across 3 groups was the most stable. One cluster including 44 BD patients, 31 controls and 5 SZ patients showed better cognition (High cluster) than the other cluster with 24 BD patients, 35 SZ patients and 5 controls (Low cluster). BD patients in the High cluster performed better than BD patients in the Low cluster across cognitive domains. Within each cluster, participants with different clinical diagnoses showed different profiles across cognitive domains. All patients are in the chronic phase and out of mood episode at the time of assessment and most of the assessment were behavioral measures. This study identified two clusters with shared cognitive phenotype profiles that were not proxies for clinical diagnoses. The finding of better social cognitive performance of BD patients than SZ patients in the Lowe cluster suggest that relatively preserved social cognition may be important to identify disease process distinct to each disorder. Copyright © 2016 Elsevier B.V. All rights reserved.

  13. Molecular characterization of the PR-toxin gene cluster in Penicillium roqueforti and Penicillium chrysogenum: cross talk of secondary metabolite pathways.

    PubMed

    Hidalgo, Pedro I; Ullán, Ricardo V; Albillos, Silvia M; Montero, Olimpio; Fernández-Bodega, María Ángeles; García-Estrada, Carlos; Fernández-Aguado, Marta; Martín, Juan-Francisco

    2014-01-01

    The PR-toxin is a potent mycotoxin produced by Penicillium roqueforti in moulded grains and grass silages and may contaminate blue-veined cheese. The PR-toxin derives from the 15 carbon atoms sesquiterpene aristolochene formed by the aristolochene synthase (encoded by ari1). We have cloned and sequenced a four gene cluster that includes the ari1 gene from P. roqueforti. Gene silencing of each of the four genes (named prx1 to prx4) resulted in a reduction of 65-75% in the production of PR-toxin indicating that the four genes encode enzymes involved in PR-toxin biosynthesis. Interestingly the four silenced mutants overproduce large amounts of mycophenolic acid, an antitumor compound formed by an unrelated pathway suggesting a cross-talk of PR-toxin and mycophenolic acid production. An eleven gene cluster that includes the above mentioned four prx genes and a 14-TMS drug/H(+) antiporter was found in the genome of Penicillium chrysogenum. This eleven gene cluster has been reported to be very poorly expressed in a transcriptomic study of P. chrysogenum genes under conditions of penicillin production (strongly aerated cultures). We found that this apparently silent gene cluster is able to produce PR-toxin in P. chrysogenum under static culture conditions on hydrated rice medium. Noteworthily, the production of PR-toxin was 2.6-fold higher in P. chrysogenum npe10, a strain deleted in the 56.8kb amplifiable region containing the pen gene cluster, than in the parental strain Wisconsin 54-1255 providing another example of cross-talk between secondary metabolite pathways in this fungus. A detailed PR-toxin biosynthesis pathway is proposed based on all available evidence. Copyright © 2013 Elsevier Inc. All rights reserved.

  14. Regional health care planning: a methodology to cluster facilities using community utilization patterns

    PubMed Central

    2013-01-01

    Background Community-based health care planning and regulation necessitates grouping facilities and areal units into regions of similar health care use. Limited research has explored the methodologies used in creating these regions. We offer a new methodology that clusters facilities based on similarities in patient utilization patterns and geographic location. Our case study focused on Hospital Groups in Michigan, the allocation units used for predicting future inpatient hospital bed demand in the state’s Bed Need Methodology. The scientific, practical, and political concerns that were considered throughout the formulation and development of the methodology are detailed. Methods The clustering methodology employs a 2-step K-means + Ward’s clustering algorithm to group hospitals. The final number of clusters is selected using a heuristic that integrates both a statistical-based measure of cluster fit and characteristics of the resulting Hospital Groups. Results Using recent hospital utilization data, the clustering methodology identified 33 Hospital Groups in Michigan. Conclusions Despite being developed within the politically charged climate of Certificate of Need regulation, we have provided an objective, replicable, and sustainable methodology to create Hospital Groups. Because the methodology is built upon theoretically sound principles of clustering analysis and health care service utilization, it is highly transferable across applications and suitable for grouping facilities or areal units. PMID:23964905

  15. Regional health care planning: a methodology to cluster facilities using community utilization patterns.

    PubMed

    Delamater, Paul L; Shortridge, Ashton M; Messina, Joseph P

    2013-08-22

    Community-based health care planning and regulation necessitates grouping facilities and areal units into regions of similar health care use. Limited research has explored the methodologies used in creating these regions. We offer a new methodology that clusters facilities based on similarities in patient utilization patterns and geographic location. Our case study focused on Hospital Groups in Michigan, the allocation units used for predicting future inpatient hospital bed demand in the state's Bed Need Methodology. The scientific, practical, and political concerns that were considered throughout the formulation and development of the methodology are detailed. The clustering methodology employs a 2-step K-means + Ward's clustering algorithm to group hospitals. The final number of clusters is selected using a heuristic that integrates both a statistical-based measure of cluster fit and characteristics of the resulting Hospital Groups. Using recent hospital utilization data, the clustering methodology identified 33 Hospital Groups in Michigan. Despite being developed within the politically charged climate of Certificate of Need regulation, we have provided an objective, replicable, and sustainable methodology to create Hospital Groups. Because the methodology is built upon theoretically sound principles of clustering analysis and health care service utilization, it is highly transferable across applications and suitable for grouping facilities or areal units.

  16. Utilizing Hierarchical Clustering to improve Efficiency of Self-Organizing Feature Map to Identify Hydrological Homogeneous Regions

    NASA Astrophysics Data System (ADS)

    Farsadnia, Farhad; Ghahreman, Bijan

    2016-04-01

    Hydrologic homogeneous group identification is considered both fundamental and applied research in hydrology. Clustering methods are among conventional methods to assess the hydrological homogeneous regions. Recently, Self-Organizing feature Map (SOM) method has been applied in some studies. However, the main problem of this method is the interpretation on the output map of this approach. Therefore, SOM is used as input to other clustering algorithms. The aim of this study is to apply a two-level Self-Organizing feature map and Ward hierarchical clustering method to determine the hydrologic homogenous regions in North and Razavi Khorasan provinces. At first by principal component analysis, we reduced SOM input matrix dimension, then the SOM was used to form a two-dimensional features map. To determine homogeneous regions for flood frequency analysis, SOM output nodes were used as input into the Ward method. Generally, the regions identified by the clustering algorithms are not statistically homogeneous. Consequently, they have to be adjusted to improve their homogeneity. After adjustment of the homogeneity regions by L-moment tests, five hydrologic homogeneous regions were identified. Finally, adjusted regions were created by a two-level SOM and then the best regional distribution function and associated parameters were selected by the L-moment approach. The results showed that the combination of self-organizing maps and Ward hierarchical clustering by principal components as input is more effective than the hierarchical method, by principal components or standardized inputs to achieve hydrologic homogeneous regions.

  17. Identification of Flood Reactivity Regions via the Functional Clustering of Hydrographs

    NASA Astrophysics Data System (ADS)

    Brunner, Manuela I.; Viviroli, Daniel; Furrer, Reinhard; Seibert, Jan; Favre, Anne-Catherine

    2018-03-01

    Flood hydrograph shapes contain valuable information on the flood-generation mechanisms of a catchment. To make good use of this information, we express flood hydrograph shapes as continuous functions using a functional data approach. We propose a clustering approach based on functional data for flood hydrograph shapes to identify a set of representative hydrograph shapes on a catchment scale and use these catchment-specific sets of representative hydrographs to establish regions of catchments with similar flood reactivity on a regional scale. We applied this approach to flood samples of 163 medium-size Swiss catchments. The results indicate that three representative hydrograph shapes sufficiently describe the hydrograph shape variability within a catchment and therefore can be used as a proxy for the flood behavior of a catchment. These catchment-specific sets of three hydrographs were used to group the catchments into three reactivity regions of similar flood behavior. These regions were not only characterized by similar hydrograph shapes and reactivity but also by event magnitudes and triggering event conditions. We envision these regions to be useful in regionalization studies, regional flood frequency analyses, and to allow for the construction of synthetic design hydrographs in ungauged catchments. The clustering approach based on functional data which establish these regions is very flexible and has the potential to be extended to other geographical regions or toward the use in climate impact studies.

  18. The Awareness and Educational Status on Oral Health of Elite Athletes: A Cross-Sectional Study with Cluster Analysis

    ERIC Educational Resources Information Center

    Ozgur, Bahar Odabas

    2016-01-01

    In this cross-sectional survey, this study aimed to determine the factors associated with oral health of elite athletes and to determine the clustering tendency of the variables by dendrogram, and to determine the relationship between predefined clusters and see how these clusters can converge. A total of 97 elite (that is, top-level performing)…

  19. IDENTIFICATION OF MEMBERS IN THE CENTRAL AND OUTER REGIONS OF GALAXY CLUSTERS

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Serra, Ana Laura; Diaferio, Antonaldo, E-mail: serra@ph.unito.it

    2013-05-10

    The caustic technique measures the mass of galaxy clusters in both their virial and infall regions and, as a byproduct, yields the list of cluster galaxy members. Here we use 100 galaxy clusters with mass M{sub 200} {>=} 10{sup 14} h {sup -1} M{sub Sun} extracted from a cosmological N-body simulation of a {Lambda}CDM universe to test the ability of the caustic technique to identify the cluster galaxy members. We identify the true three-dimensional members as the gravitationally bound galaxies. The caustic technique uses the caustic location in the redshift diagram to separate the cluster members from the interlopers. Wemore » apply the technique to mock catalogs containing 1000 galaxies in the field of view of 12 h {sup -1} Mpc on a side at the cluster location. On average, this sample size roughly corresponds to 180 real galaxy members within 3r{sub 200}, similar to recent redshift surveys of cluster regions. The caustic technique yields a completeness, the fraction of identified true members, f{sub c} = 0.95 {+-} 0.03, within 3r{sub 200}. The contamination, the fraction of interlopers in the observed catalog of members, increases from f{sub i}=0.020{sup +0.046}{sub -0.015} at r{sub 200} to f{sub i}=0.08{sup +0.11}{sub -0.05} at 3r{sub 200}. No other technique for the identification of the members of a galaxy cluster provides such large completeness and small contamination at these large radii. The caustic technique assumes spherical symmetry and the asphericity of the cluster is responsible for most of the spread of the completeness and the contamination. By applying the technique to an approximately spherical system obtained by stacking the individual clusters, the spreads decrease by at least a factor of two. We finally estimate the cluster mass within 3r{sub 200} after removing the interlopers: for individual clusters, the mass estimated with the virial theorem is unbiased and within 30% of the actual mass; this spread decreases to less than 10% for the

  20. Cross-layer cluster-based energy-efficient protocol for wireless sensor networks.

    PubMed

    Mammu, Aboobeker Sidhik Koyamparambil; Hernandez-Jayo, Unai; Sainz, Nekane; de la Iglesia, Idoia

    2015-04-09

    Recent developments in electronics and wireless communications have enabled the improvement of low-power and low-cost wireless sensors networks (WSNs). One of the most important challenges in WSNs is to increase the network lifetime due to the limited energy capacity of the network nodes. Another major challenge in WSNs is the hot spots that emerge as locations under heavy traffic load. Nodes in such areas quickly drain energy resources, leading to disconnection in network services. In such an environment, cross-layer cluster-based energy-efficient algorithms (CCBE) can prolong the network lifetime and energy efficiency. CCBE is based on clustering the nodes to different hexagonal structures. A hexagonal cluster consists of cluster members (CMs) and a cluster head (CH). The CHs are selected from the CMs based on nodes near the optimal CH distance and the residual energy of the nodes. Additionally, the optimal CH distance that links to optimal energy consumption is derived. To balance the energy consumption and the traffic load in the network, the CHs are rotated among all CMs. In WSNs, energy is mostly consumed during transmission and reception. Transmission collisions can further decrease the energy efficiency. These collisions can be avoided by using a contention-free protocol during the transmission period. Additionally, the CH allocates slots to the CMs based on their residual energy to increase sleep time. Furthermore, the energy consumption of CH can be further reduced by data aggregation. In this paper, we propose a data aggregation level based on the residual energy of CH and a cost-aware decision scheme for the fusion of data. Performance results show that the CCBE scheme performs better in terms of network lifetime, energy consumption and throughput compared to low-energy adaptive clustering hierarchy (LEACH) and hybrid energy-efficient distributed clustering (HEED).

  1. The Gas Distribution in the Outer Regions of Galaxy Clusters

    NASA Technical Reports Server (NTRS)

    Eckert, D.; Vazza, F.; Ettori, S.; Molendi, S.; Nagai, D.; Lau, E. T.; Roncarelli, M.; Rossetti, M.; Snowden, L.; Gastaldello, F.

    2012-01-01

    Aims. We present our analysis of a local (z = 0.04 - 0.2) sample of 31 galaxy clusters with the aim of measuring the density of the X-ray emitting gas in cluster outskirts. We compare our results with numerical simulations to set constraints on the azimuthal symmetry and gas clumping in the outer regions of galaxy clusters. Methods. We have exploited the large field-of-view and low instrumental background of ROSAT/PSPC to trace the density of the intracluster gas out to the virial radius, We stacked the density profiles to detect a signal beyond T200 and measured the typical density and scatter in cluster outskirts. We also computed the azimuthal scatter of the profiles with respect to the mean value to look for deviations from spherical symmetry. Finally, we compared our average density and scatter profiles with the results of numerical simulations. Results. As opposed to some recent Suzaku results, and confirming previous evidence from ROSAT and Chandra, we observe a steepening of the density profiles beyond approximately r(sub 500). Comparing our density profiles with simulations, we find that non-radiative runs predict density profiles that are too steep, whereas runs including additional physics and/ or treating gas clumping agree better with the observed gas distribution. We report high-confidence detection of a systematic difference between cool-core and non cool-core clusters beyond approximately 0.3r(sub 200), which we explain by a different distribution of the gas in the two classes. Beyond approximately r(sub 500), galaxy clusters deviate significantly from spherical symmetry, with only small differences between relaxed and disturbed systems. We find good agreement between the observed and predicted scatter profiles, but only when the 1% densest clumps are filtered out in the ENZO simulations. Conclusions. Comparing our results with numerical simulations, we find that non-radiative simulations fail to reproduce the gas distribution, even well outside

  2. Privacy Protection Versus Cluster Detection in Spatial Epidemiology

    PubMed Central

    Olson, Karen L.; Grannis, Shaun J.; Mandl, Kenneth D.

    2006-01-01

    Objectives. Patient data that includes precise locations can reveal patients’ identities, whereas data aggregated into administrative regions may preserve privacy and confidentiality. We investigated the effect of varying degrees of address precision (exact latitude and longitude vs the center points of zip code or census tracts) on detection of spatial clusters of cases. Methods. We simulated disease outbreaks by adding supplementary spatially clustered emergency department visits to authentic hospital emergency department syndromic surveillance data. We identified clusters with a spatial scan statistic and evaluated detection rate and accuracy. Results. More clusters were identified, and clusters were more accurately detected, when exact locations were used. That is, these clusters contained at least half of the simulated points and involved few additional emergency department visits. These results were especially apparent when the synthetic clustered points crossed administrative boundaries and fell into multiple zip code or census tracts. Conclusions. The spatial cluster detection algorithm performed better when addresses were analyzed as exact locations than when they were analyzed as center points of zip code or census tracts, particularly when the clustered points crossed administrative boundaries. Use of precise addresses offers improved performance, but this practice must be weighed against privacy concerns in the establishment of public health data exchange policies. PMID:17018828

  3. Privacy protection versus cluster detection in spatial epidemiology.

    PubMed

    Olson, Karen L; Grannis, Shaun J; Mandl, Kenneth D

    2006-11-01

    Patient data that includes precise locations can reveal patients' identities, whereas data aggregated into administrative regions may preserve privacy and confidentiality. We investigated the effect of varying degrees of address precision (exact latitude and longitude vs the center points of zip code or census tracts) on detection of spatial clusters of cases. We simulated disease outbreaks by adding supplementary spatially clustered emergency department visits to authentic hospital emergency department syndromic surveillance data. We identified clusters with a spatial scan statistic and evaluated detection rate and accuracy. More clusters were identified, and clusters were more accurately detected, when exact locations were used. That is, these clusters contained at least half of the simulated points and involved few additional emergency department visits. These results were especially apparent when the synthetic clustered points crossed administrative boundaries and fell into multiple zip code or census tracts. The spatial cluster detection algorithm performed better when addresses were analyzed as exact locations than when they were analyzed as center points of zip code or census tracts, particularly when the clustered points crossed administrative boundaries. Use of precise addresses offers improved performance, but this practice must be weighed against privacy concerns in the establishment of public health data exchange policies.

  4. Clustering of diet, physical activity and sedentary behaviour among Australian children: cross-sectional and longitudinal associations with overweight and obesity.

    PubMed

    Leech, R M; McNaughton, S A; Timperio, A

    2015-07-01

    Evidence suggests diet, physical activity (PA) and sedentary behaviour cluster together in children, but research supporting an association with overweight/obesity is equivocal. Furthermore, the stability of clusters over time is unknown. The aim of this study was to examine the clustering of diet, PA and sedentary behaviour in Australian children and cross-sectional and longitudinal associations with overweight/obesity. Stability of obesity-related clusters over 3 years was also examined. Data were drawn from the baseline (T1: 2002/2003) and follow-up waves (T2: 2005/2006) of the Health Eating and Play Study. Parents of Australian children aged 5-6 (n=87) and 10-12 years (n=123) completed questionnaires. Children wore accelerometers and height and weight were measured. Obesity-related clusters were determined using K-medians cluster analysis. Multivariate regression models assessed cross-sectional and longitudinal associations between cluster membership, and body mass index (BMI) Z-score and weight status. Kappa statistics assessed cluster stability over time. Three clusters, labelled 'most healthy', 'energy-dense (ED) consumers who watch TV' and 'high sedentary behaviour/low moderate-to-vigorous PA' were identified at baseline and at follow-up. No cross-sectional associations were found between cluster membership, and BMI Z-score or weight status at baseline. Longitudinally, children in the 'ED consumers who watch TV' cluster had a higher odds of being overweight/obese at follow-up (odds ratio=2.8; 95% confidence interval: 1.1, 6.9; P<0.05). Tracking of cluster membership was fair to moderate in younger (K=0.24; P=0.0001) and older children (K=0.46; P<0.0001). This study identified an unhealthy cluster of TV viewing with ED food/drink consumption, which predicted overweight/obesity in a small longitudinal sample of Australian children. Cluster stability was fair to moderate over 3 years and is a novel finding. Prospective research in larger samples is needed to

  5. REGIONAL-SCALE WIND FIELD CLASSIFICATION EMPLOYING CLUSTER ANALYSIS

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Glascoe, L G; Glaser, R E; Chin, H S

    2004-06-17

    The classification of time-varying multivariate regional-scale wind fields at a specific location can assist event planning as well as consequence and risk analysis. Further, wind field classification involves data transformation and inference techniques that effectively characterize stochastic wind field variation. Such a classification scheme is potentially useful for addressing overall atmospheric transport uncertainty and meteorological parameter sensitivity issues. Different methods to classify wind fields over a location include the principal component analysis of wind data (e.g., Hardy and Walton, 1978) and the use of cluster analysis for wind data (e.g., Green et al., 1992; Kaufmann and Weber, 1996). The goalmore » of this study is to use a clustering method to classify the winds of a gridded data set, i.e, from meteorological simulations generated by a forecast model.« less

  6. 75 FR 40856 - Federal Register Meeting Notice; Webinar About Regional Innovation Clusters RFP

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-14

    ... potential Offerors about the Regional Innovation Clusters RFP. For more information please go to http://www.sba.gov/clusters/index.html . The RFP may be found on http://www.fedbizopps.gov . Logistical Information: The webinar will be held on Thursday, July 15, 2010. For details, please visit http://www.sba.gov...

  7. Mapping hotspots of threatened species traded in bushmeat markets in the Cross-Sanaga rivers region.

    PubMed

    Fa, John E; Farfán, Miguel Angel; Marquez, Ana Luz; Duarte, Jesús; Nackoney, Janet; Hall, Amy; Dupain, Jef; Seymour, Sarah; Johnson, Paul J; MacDonald, David W; Vargas, J Mario

    2014-02-01

    Bushmeat markets exist in many countries in West and Central Africa, and data on species sold can be used to detect patterns of wildlife trade in a region. We surveyed 89 markets within the Cross-Sanaga rivers region, West Africa. In each market, we counted the number of carcasses of each taxon sold. During a 6-month period (7594 market days), 44 mammal species were traded. Thirteen species were on the International Union for Conservation of Nature (IUCN) Red List or protected under national legislation, and at least 1 threatened species was traded in 88 of the 89 markets. We used these data to identify market groups that traded similar species assemblages. Using cluster analyses, we detected 8 market groups that were also geographically distinct. Market groups differed in the diversity of species, evenness of species, and dominant, prevalent, and characteristic species traded. We mapped the distribution of number of threatened species traded across the study region. Most threatened species were sold in markets nearest 2 national parks, Korup National Park in Cameroon and Cross River in Nigeria. To assess whether the threatened-species trade hotspots coincided with the known ranges of these species, we mapped the overlap of all threatened species traded. Markets selling more threatened species overlapped with those regions that had higher numbers of these. Our study can provide wildlife managers in the region with better tools to discern zones within which to focus policing efforts and reduce threats to species that are threatened by the bushmeat trade. © 2013 Society for Conservation Biology.

  8. Multi-wavelength Morphological Study Of Star Forming Regions In Nearby Cluster-rich Lirgs

    NASA Astrophysics Data System (ADS)

    Vavilkin, Tatjana; Evans, A.; Mazzarella, J.; Surace, J.; Kim, D.; Howell, J.; Armus, L.; GOALS Team

    2009-05-01

    Luminous Infrared Galaxies (LIRGs) are believed to play an important role in star formation history of the universe. Many LIRGs undergo intense bursts of star formation as a result of interaction/merger process. Given the dusty nature of LIRGs, it is necessary to probe Luminous Infrared Galaxies at multiple wavelengths. The Great Observatories All-sky LIRG Survey (GOALS) combines data from NASA's Spitzer, Hubble, Chandra and GALEX observatories and offers a unique opportunity to gain insights into the physical processes in these highly dust enshrouded systems. We examine a sample of 11 nearby (z < 0.03) cluster-rich (> 200 clusters as seen in HST ACS images) LIRG systems at various interaction stages. The combined HST ACS optical imaging, Spitzer IRAC 8 micron channel and GALEX near-UV imaging allows us to access the properties of visible and obscured star forming regions. We study the spatial distribution of star forming regions at these wavelengths, correlate locations of young stellar clusters with PAH and UV emission regions and trace changes with merger stage.

  9. High star formation activity in the central region of a distant cluster at z = 1.46

    NASA Astrophysics Data System (ADS)

    Hayashi, Masao; Kodama, Tadayuki; Koyama, Yusei; Tanaka, Ichi; Shimasaku, Kazuhiro; Okamura, Sadanori

    2010-03-01

    We present an unbiased deep [OII] emission survey of a cluster XMMXCS J2215.9-1738 at z = 1.46, the most distant cluster to date with a detection of extended X-ray emission. With wide-field optical and near-infrared cameras (Suprime-Cam and MOIRCS, respectively) on Subaru telescope, we performed deep imaging with a narrow-band filter NB912 (λc = 9139 Å, Δλ = 134 Å) as well as broad-band filters (B,z',J and Ks). From the photometric catalogues, we have identified 44 [OII] emitters in the cluster central region of 6 × 6 arcmin2 down to a dust-free star formation rate (SFR) of 2.6Msolaryr-1 (3σ). Interestingly, it is found that there are many [OII] emitters even in the central high-density region. In fact, the fraction of [OII] emitters to the cluster members as well as their SFRs and equivalent widths stay almost constant with decreasing cluster-centric distance up to the cluster core. Unlike clusters at lower redshifts (z <~ 1) where star formation activity is mostly quenched in their central regions, this higher redshift XMMXCS J2215.9-1738 cluster shows its high star formation activity even at its centre, suggesting that we are beginning to enter the formation epoch of some galaxies in the cluster core eventually. Moreover, we find a deficit of galaxies on the red sequence at magnitudes fainter than ~M* + 0.5 on the colour-magnitude diagram. This break magnitude is brighter than that of lower redshift clusters, and it is likely that we are seeing the formation phase of more massive red galaxies in the cluster core at z ~ 1. These results may indicate inside-out and down-sizing propagation of star formation activity in the course of cluster evolution.

  10. Choosing appropriate analysis methods for cluster randomised cross-over trials with a binary outcome.

    PubMed

    Morgan, Katy E; Forbes, Andrew B; Keogh, Ruth H; Jairath, Vipul; Kahan, Brennan C

    2017-01-30

    In cluster randomised cross-over (CRXO) trials, clusters receive multiple treatments in a randomised sequence over time. In such trials, there is usual correlation between patients in the same cluster. In addition, within a cluster, patients in the same period may be more similar to each other than to patients in other periods. We demonstrate that it is necessary to account for these correlations in the analysis to obtain correct Type I error rates. We then use simulation to compare different methods of analysing a binary outcome from a two-period CRXO design. Our simulations demonstrated that hierarchical models without random effects for period-within-cluster, which do not account for any extra within-period correlation, performed poorly with greatly inflated Type I errors in many scenarios. In scenarios where extra within-period correlation was present, a hierarchical model with random effects for cluster and period-within-cluster only had correct Type I errors when there were large numbers of clusters; with small numbers of clusters, the error rate was inflated. We also found that generalised estimating equations did not give correct error rates in any scenarios considered. An unweighted cluster-level summary regression performed best overall, maintaining an error rate close to 5% for all scenarios, although it lost power when extra within-period correlation was present, especially for small numbers of clusters. Results from our simulation study show that it is important to model both levels of clustering in CRXO trials, and that any extra within-period correlation should be accounted for. Copyright © 2016 John Wiley & Sons, Ltd. Copyright © 2016 John Wiley & Sons, Ltd.

  11. Off-Center Collisions between Clusters of Galaxies

    NASA Astrophysics Data System (ADS)

    Ricker, P. M.

    1998-03-01

    We present numerical simulations of off-center collisions between galaxy clusters made using a new hydrodynamical code based on the piecewise-parabolic method (PPM) and an isolated multigrid potential solver. The current simulations follow only the intracluster gas. We have performed three high-resolution (256 × 1282) simulations of collisions between equal-mass clusters using a nonuniform grid with different values of the impact parameter (0, 5, and 10 times the cluster core radius). Using these simulations, we have studied the variation in equilibration time, luminosity enhancement during the collision, and structure of the merger remnant with varying impact parameter. We find that in off-center collisions the cluster cores (the inner regions where the pressure exceeds the ram pressure) behave quite differently from the clusters' outer regions. A strong, roughly ellipsoidal shock front, similar to that noted in previous simulations of head-on collisions, enables the cores to become bound to each other by dissipating their kinetic energy as heat in the surrounding gas. These cores survive well into the collision, dissipating their orbital angular momentum via spiral bow shocks. After the ellipsoidal shock has passed well outside the interaction region, the material left in its wake falls back onto the merger remnant formed through the inspiral of the cluster cores, creating a roughly spherical accretion shock. For less than one-half of a sound crossing time after the cores first interact, the total X-ray luminosity increases by a large factor; the magnitude of this increase depends sensitively on the size of the impact parameter. Observational evidence of the ongoing collision, in the form of bimodality and distortion in projected X-ray surface brightness and temperature maps, is present for one to two sound crossing times after the collision but only for special viewing angles. The remnant actually requires at least five crossing times to reach virial

  12. Earthquake cluster activity beneath the Tanzawa Mountains region, Japan: Migration of hypocenters and low stress drop

    NASA Astrophysics Data System (ADS)

    Yamada, T.; Yukutake, Y.

    2013-12-01

    An earthquake cluster activity was observed beneath the Tanzawa Mountains region, Japan with a depth of 20 km in the end of January, 2012. Japan Meteorological Agency (JMA) determined hypocenters of 76 earthquakes with M > 2 in the area within 50 hours. Five of them had magnitudes greater than 4 and the largest one was 5.4. Four out of the five earthquakes had the reverse-type focal mechanisms with the P axis in the NW-SE direction. First we relocated hypocenters of the activity following the method of Yukutake et al. (2012). We estimated relative arrival times of P and S waves by calculating the coefficients of the cross correlation and relocated hypocenters with the double-difference relocation method (Waldhauser and Ellsworth, 2000). We found that the cluster activity showed a migration from the first earthquake of the activity. The parabolic migration speed was consistent with the migration speed of the deep tremor sources (Ide et al., 2010) for which the fluid activity would play an important role. We then analyzed stress drops of 17 earthquakes with M > 3.5 that occurred from January, 2000 to June, 2012 in the area of the cluster activity. We calculated empirical Green's functions from waveforms of earthquakes with magnitudes of 3.0 to 3.2 and estimated stress drops of the earthquakes assuming that the source spectra can be expressed as the omega-squared model. We found that earthquakes of the cluster activity had smaller stress drops by an order of magnitude than the values of earthquakes that occurred in the same area before the cluster activity. These results suggest that the fluid played an important role for the earthquake cluster activity. That is, the fluid increased the pore pressure, decreased the effective normal stress and triggered the cluster activity. The difference of the rupture speed and the change of the rigidity might also be candidates that account for our results. They, however, can hardly explain the results quantitatively. Fig

  13. User’s guide for GcClust—An R package for clustering of regional geochemical data

    USGS Publications Warehouse

    Ellefsen, Karl J.; Smith, David B.

    2016-04-08

    GcClust is a software package developed by the U.S. Geological Survey for statistical clustering of regional geochemical data, and similar data such as regional mineralogical data. Functions within the software package are written in the R statistical programming language. These functions, their documentation, and a copy of the user’s guide are bundled together in R’s unit of sharable code, which is called a “package.” The user’s guide includes step-by-step instructions showing how the functions are used to cluster data and to evaluate the clustering results. These functions are demonstrated in this report using test data, which are included in the package.

  14. Young stellar population and star formation history ofW4 HII region/Cluster Complex

    NASA Astrophysics Data System (ADS)

    Panwar, Neelam

    2018-04-01

    The HII region/cluster complex has been a subject of numerous investigations to study the feedback effect of massive stars on their surroundings. Massive stars not only alter the morphology of the parental molecular clouds, but also influence star formation, circumstellar disks and the mass function of low-mass stars in their vicinity. However, most of the studies of low-mass stellar content of the HII regions are limited only to the nearby regions. We study the star formation in the W4 HII region using deep optical observations obtained with the archival data from Canada - France - Hawaii Telescope, Two-Micron All Sky Survey, Spitzer, Herschel and Chandra. We investigate the spatial distribution of young stellar objects in the region, their association with the remnant molecular clouds, and search for the clustering to establish the sites of recent star formation. Our analysis suggests that the influence of massive stars on circumstellar disks is significant only to thei! r immediate neighborhood. The spatial correlation of the young stars with the distribution of gas and dust of the complex indicate that the clusters would have formed in a large filamentary cloud. The observing facilities at the 3.6-m Devasthal Optical Telescope (DOT), providing high-resolution spectral and imaging capabilities, will fulfill the major objectives in the study of HII regions.

  15. The W40 region in the gould belt: An embedded cluster and H II region at the junction of filaments

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mallick, K. K.; Ojha, D. K.; Kumar, M. S. N.

    We present a multiwavelength study of the W40 star-forming region using infrared (IR) observations in the UKIRT JHK bands, Spitzer Infrared Array Camera bands, and Herschel PACS bands, 2.12 μm H{sub 2} narrowband imaging, and radio continuum observations from GMRT (610 and 1280 MHz), in a field of view (FoV) of ∼34' × 40'. Archival Spitzer observations in conjunction with near-IR observations are used to identify 1162 Class II/III and 40 Class I sources in the FoV. The nearest-neighbor stellar surface density analysis shows that the majority of these young stellar objects (YSOs) constitute the embedded cluster centered on themore » high-mass source IRS 1A South. Some YSOs, predominantly the younger population, are distributed along and trace the filamentary structures at lower stellar surface density. The cluster radius is measured to be 0.44 pc—matching well with the extent of radio emission—with a peak density of 650 pc{sup –2}. The JHK data are used to map the extinction in the region, which is subsequently used to compute the cloud mass—126 M {sub ☉} and 71 M {sub ☉} for the central cluster and the northern IRS 5 region, respectively. H{sub 2} narrowband imaging shows significant emission, which prominently resembles fluorescent emission arising at the borders of dense regions. Radio continuum analysis shows that this region has a blister morphology, with the radio peak coinciding with a protostellar source. Free-free emission spectral energy distribution analysis is used to obtain physical parameters of the overall photoionized region and the IRS 5 sub-region. This multiwavelength scenario is suggestive of star formation having resulted from the merging of multiple filaments to form a hub. Star formation seems to have taken place in two successive epochs, with the first epoch traced by the central cluster and the high-mass star(s)—followed by a second epoch that is spreading into the filaments as uncovered by the Class I sources and even

  16. Manual hierarchical clustering of regional geochemical data using a Bayesian finite mixture model

    USGS Publications Warehouse

    Ellefsen, Karl J.; Smith, David

    2016-01-01

    Interpretation of regional scale, multivariate geochemical data is aided by a statistical technique called “clustering.” We investigate a particular clustering procedure by applying it to geochemical data collected in the State of Colorado, United States of America. The clustering procedure partitions the field samples for the entire survey area into two clusters. The field samples in each cluster are partitioned again to create two subclusters, and so on. This manual procedure generates a hierarchy of clusters, and the different levels of the hierarchy show geochemical and geological processes occurring at different spatial scales. Although there are many different clustering methods, we use Bayesian finite mixture modeling with two probability distributions, which yields two clusters. The model parameters are estimated with Hamiltonian Monte Carlo sampling of the posterior probability density function, which usually has multiple modes. Each mode has its own set of model parameters; each set is checked to ensure that it is consistent both with the data and with independent geologic knowledge. The set of model parameters that is most consistent with the independent geologic knowledge is selected for detailed interpretation and partitioning of the field samples.

  17. Photometric and Spectroscopic Survey of the Cluster [DBS2003] 156 Associated with the H II Region G331.1-0.5

    NASA Astrophysics Data System (ADS)

    Pinheiro, M. C.; Ortiz, R.; Abraham, Z.; Copetti, M. V. F.

    2016-05-01

    The Norma section of the Milky Way is especially interesting because it crosses three spiral arms: Sagittarius-Carina, Scutum-Crux and the Norma arm itself. Distance determinations of embedded young stellar clusters can contribute to define the spiral structure in this part of the Galaxy. However, spectrophotometric distances were obtained for only a few of these clusters in Norma. We present a photometric and spectroscopic study in the NIR of the [DBS2003] 156 stellar cluster, associated with the H II region G331.1-0.5. We aim to find the ionizing sources of the H II region and determine its distance. The cluster was observed in the J, H, and {K}{{s}} bands and eight potential massive stars were chosen among the detected sources according to color criteria; subsequent spectroscopy of these candidates was performed with the Ohio State Infrared Imager/Spectrometer spectrograph attached to the Southern Observatory for Astrophysical Research 4.1 m telescope. We identified and classified spectroscopically four early-type stars: IRS 176 (O8 V), IRS 308 (O-type), IRS 310 (O6 V), and IRS 71 (B1 Iab). Based on the proximity of IRS 176 and 308 with the radio continuum emission peaks and their relative positions with respect to the warm dust mid-infrared emission, we concluded that these two stars are the main ionizing sources of the H ii region G331.1-0.5. The mean spectrophotometric distance of IRS 176 and 310 of 3.38 ± 0.58 kpc is similar to that obtained in a previous work for two early-type stars of the neighbor cluster [DBS2003] 157 of 3.29 ± 0.58 kpc. The narrow range of radial velocities of radio sources in the area of the clusters [DBS2003] 156 and 157 and their similar visual extinction indicate that these clusters are physically associated. A common distance of 3.34 ± 0.34 kpc is derived for the system [DBS2003] 156 and 157. Based on observations obtained at the Southern Observatory for Astrophysical Research (SOAR), a joint project of the Ministério de Ci

  18. Minimum number of clusters and comparison of analysis methods for cross sectional stepped wedge cluster randomised trials with binary outcomes: A simulation study.

    PubMed

    Barker, Daniel; D'Este, Catherine; Campbell, Michael J; McElduff, Patrick

    2017-03-09

    Stepped wedge cluster randomised trials frequently involve a relatively small number of clusters. The most common frameworks used to analyse data from these types of trials are generalised estimating equations and generalised linear mixed models. A topic of much research into these methods has been their application to cluster randomised trial data and, in particular, the number of clusters required to make reasonable inferences about the intervention effect. However, for stepped wedge trials, which have been claimed by many researchers to have a statistical power advantage over the parallel cluster randomised trial, the minimum number of clusters required has not been investigated. We conducted a simulation study where we considered the most commonly used methods suggested in the literature to analyse cross-sectional stepped wedge cluster randomised trial data. We compared the per cent bias, the type I error rate and power of these methods in a stepped wedge trial setting with a binary outcome, where there are few clusters available and when the appropriate adjustment for a time trend is made, which by design may be confounding the intervention effect. We found that the generalised linear mixed modelling approach is the most consistent when few clusters are available. We also found that none of the common analysis methods for stepped wedge trials were both unbiased and maintained a 5% type I error rate when there were only three clusters. Of the commonly used analysis approaches, we recommend the generalised linear mixed model for small stepped wedge trials with binary outcomes. We also suggest that in a stepped wedge design with three steps, at least two clusters be randomised at each step, to ensure that the intervention effect estimator maintains the nominal 5% significance level and is also reasonably unbiased.

  19. Nucleus and cytoplasm segmentation in microscopic images using K-means clustering and region growing.

    PubMed

    Sarrafzadeh, Omid; Dehnavi, Alireza Mehri

    2015-01-01

    Segmentation of leukocytes acts as the foundation for all automated image-based hematological disease recognition systems. Most of the time, hematologists are interested in evaluation of white blood cells only. Digital image processing techniques can help them in their analysis and diagnosis. The main objective of this paper is to detect leukocytes from a blood smear microscopic image and segment them into their two dominant elements, nucleus and cytoplasm. The segmentation is conducted using two stages of applying K-means clustering. First, the nuclei are segmented using K-means clustering. Then, a proposed method based on region growing is applied to separate the connected nuclei. Next, the nuclei are subtracted from the original image. Finally, the cytoplasm is segmented using the second stage of K-means clustering. The results indicate that the proposed method is able to extract the nucleus and cytoplasm regions accurately and works well even though there is no significant contrast between the components in the image. In this paper, a method based on K-means clustering and region growing is proposed in order to detect leukocytes from a blood smear microscopic image and segment its components, the nucleus and the cytoplasm. As region growing step of the algorithm relies on the information of edges, it will not able to separate the connected nuclei more accurately in poor edges and it requires at least a weak edge to exist between the nuclei. The nucleus and cytoplasm segments of a leukocyte can be used for feature extraction and classification which leads to automated leukemia detection.

  20. Characterization of Staphylococcus and Corynebacterium Clusters in the Human Axillary Region

    PubMed Central

    Callewaert, Chris; Kerckhof, Frederiek-Maarten; Granitsiotis, Michael S.; Van Gele, Mireille; Van de Wiele, Tom; Boon, Nico

    2013-01-01

    The skin microbial community is regarded as essential for human health and well-being, but likewise plays an important role in the formation of body odor in, for instance, the axillae. Few molecular-based research was done on the axillary microbiome. This study typified the axillary microbiome of a group of 53 healthy subjects. A profound view was obtained of the interpersonal, intrapersonal and temporal diversity of the human axillary microbiota. Denaturing gradient gel electrophoresis (DGGE) and next generation sequencing on 16S rRNA gene region were combined and used as extent to each other. Two important clusters were characterized, where Staphylococcus and Corynebacterium species were the abundant species. Females predominantly clustered within the Staphylococcus cluster (87%, n = 17), whereas males clustered more in the Corynebacterium cluster (39%, n = 36). The axillary microbiota was unique to each individual. Left-right asymmetry occurred in about half of the human population. For the first time, an elaborate study was performed on the dynamics of the axillary microbiome. A relatively stable axillary microbiome was noticed, although a few subjects evolved towards another stable community. The deodorant usage had a proportional linear influence on the species diversity of the axillary microbiome. PMID:23950955

  1. Energy Efficient Medium Access Control Protocol for Clustered Wireless Sensor Networks with Adaptive Cross-Layer Scheduling.

    PubMed

    Sefuba, Maria; Walingo, Tom; Takawira, Fambirai

    2015-09-18

    This paper presents an Energy Efficient Medium Access Control (MAC) protocol for clustered wireless sensor networks that aims to improve energy efficiency and delay performance. The proposed protocol employs an adaptive cross-layer intra-cluster scheduling and an inter-cluster relay selection diversity. The scheduling is based on available data packets and remaining energy level of the source node (SN). This helps to minimize idle listening on nodes without data to transmit as well as reducing control packet overhead. The relay selection diversity is carried out between clusters, by the cluster head (CH), and the base station (BS). The diversity helps to improve network reliability and prolong the network lifetime. Relay selection is determined based on the communication distance, the remaining energy and the channel quality indicator (CQI) for the relay cluster head (RCH). An analytical framework for energy consumption and transmission delay for the proposed MAC protocol is presented in this work. The performance of the proposed MAC protocol is evaluated based on transmission delay, energy consumption, and network lifetime. The results obtained indicate that the proposed MAC protocol provides improved performance than traditional cluster based MAC protocols.

  2. Energy Efficient Medium Access Control Protocol for Clustered Wireless Sensor Networks with Adaptive Cross-Layer Scheduling

    PubMed Central

    Sefuba, Maria; Walingo, Tom; Takawira, Fambirai

    2015-01-01

    This paper presents an Energy Efficient Medium Access Control (MAC) protocol for clustered wireless sensor networks that aims to improve energy efficiency and delay performance. The proposed protocol employs an adaptive cross-layer intra-cluster scheduling and an inter-cluster relay selection diversity. The scheduling is based on available data packets and remaining energy level of the source node (SN). This helps to minimize idle listening on nodes without data to transmit as well as reducing control packet overhead. The relay selection diversity is carried out between clusters, by the cluster head (CH), and the base station (BS). The diversity helps to improve network reliability and prolong the network lifetime. Relay selection is determined based on the communication distance, the remaining energy and the channel quality indicator (CQI) for the relay cluster head (RCH). An analytical framework for energy consumption and transmission delay for the proposed MAC protocol is presented in this work. The performance of the proposed MAC protocol is evaluated based on transmission delay, energy consumption, and network lifetime. The results obtained indicate that the proposed MAC protocol provides improved performance than traditional cluster based MAC protocols. PMID:26393608

  3. Transcriptional organization of the DNA region controlling expression of the K99 gene cluster.

    PubMed

    Roosendaal, B; Damoiseaux, J; Jordi, W; de Graaf, F K

    1989-01-01

    The transcriptional organization of the K99 gene cluster was investigated in two ways. First, the DNA region, containing the transcriptional signals was analyzed using a transcription vector system with Escherichia coli galactokinase (GalK) as assayable marker and second, an in vitro transcription system was employed. A detailed analysis of the transcription signals revealed that a strong promoter PA and a moderate promoter PB are located upstream of fanA and fanB, respectively. No promoter activity was detected in the intercistronic region between fanB and fanC. Factor-dependent terminators of transcription were detected and are probably located in the intercistronic region between fanA and fanB (T1), and between fanB and fanC (T2). A third terminator (T3) was observed between fanC and fanD and has an efficiency of 90%. Analysis of the regulatory region in an in vitro transcription system confirmed the location of the respective transcription signals. A model for the transcriptional organization of the K99 cluster is presented. Indications were obtained that the trans-acting regulatory polypeptides FanA and FanB both function as anti-terminators. A model for the regulation of expression of the K99 gene cluster is postulated.

  4. Study of Seismic Clusters at Bahía de Banderas Region, Mexico

    NASA Astrophysics Data System (ADS)

    Nunez-Cornu, F. J.; Rutz-Lopez, M.; Suarez-Plascencia, C.; Trejo-Gomez, E.

    2010-12-01

    Given that the coast in the states of Jalisco and south of the state of Nayarit is located within a region of high seismic potential and also because population is increasing, perhaps motivated by the development of tourism, the Civil Defense authorities of Jalisco and the Centro de Sismología y Volcanología de Occidente-SisVOc of Universidad de Guadalajara started in the year 2000 a joint project to study the seismic risk of the region, including the seismic monitoring of Colima volcano (located between the states of Jalisco and Colima). This work focuses on the study of seismicity in the area of Bahía de Banderas and northern coast of Jalisco. To this end, we perform an analysis of available seismograms to characterize active structures, their relationship to surface morphology, and possible reach of these structures into the shallow parts of the bay. The data used in this work are waveforms recorded during the year 2003 during which the seismograph network spanned the region of study. Our method is based on the identification of seismic clusters or families using cross-correlation of waveforms, earthquake relocation and modeling of fault planes. From an initial data set of 404 earthquakes located during 2003, 96 earthquakes could be related to 17 potentially active continental structures. A modeling of fault planes was possible for 11 of these structures. Subgroups of 7 structures are aligned parallel to the Middle America Trench, a possible consequence of oblique subduction. The magnitudes of earthquakes grouped into families is less than 3.6 (Ml), corresponding to fault dimensions of hundreds of meters.

  5. Nucleus and cytoplasm segmentation in microscopic images using K-means clustering and region growing

    PubMed Central

    Sarrafzadeh, Omid; Dehnavi, Alireza Mehri

    2015-01-01

    Background: Segmentation of leukocytes acts as the foundation for all automated image-based hematological disease recognition systems. Most of the time, hematologists are interested in evaluation of white blood cells only. Digital image processing techniques can help them in their analysis and diagnosis. Materials and Methods: The main objective of this paper is to detect leukocytes from a blood smear microscopic image and segment them into their two dominant elements, nucleus and cytoplasm. The segmentation is conducted using two stages of applying K-means clustering. First, the nuclei are segmented using K-means clustering. Then, a proposed method based on region growing is applied to separate the connected nuclei. Next, the nuclei are subtracted from the original image. Finally, the cytoplasm is segmented using the second stage of K-means clustering. Results: The results indicate that the proposed method is able to extract the nucleus and cytoplasm regions accurately and works well even though there is no significant contrast between the components in the image. Conclusions: In this paper, a method based on K-means clustering and region growing is proposed in order to detect leukocytes from a blood smear microscopic image and segment its components, the nucleus and the cytoplasm. As region growing step of the algorithm relies on the information of edges, it will not able to separate the connected nuclei more accurately in poor edges and it requires at least a weak edge to exist between the nuclei. The nucleus and cytoplasm segments of a leukocyte can be used for feature extraction and classification which leads to automated leukemia detection. PMID:26605213

  6. Investigating cluster astrophysics and cosmology with cross-correlation of the thermal Sunyaev-Zel'dovich effect and weak lensing

    NASA Astrophysics Data System (ADS)

    Osato, Ken; Flender, Samuel; Nagai, Daisuke; Shirasaki, Masato; Yoshida, Naoki

    2018-03-01

    Recent detections of the cross-correlation of the thermal Sunyaev-Zel'dovich (tSZ) effect and weak gravitational lensing (WL) enable unique studies of cluster astrophysics and cosmology. In this work, we present constraints on the amplitude of the non-thermal pressure fraction in galaxy clusters, α0, and the amplitude of the matter power spectrum, σ8, using measurements of the tSZ power spectrum from Planck, and the tSZ-WL cross-correlation from Planck and the Red Cluster Sequence Lensing Survey. We fit the data to a semi-analytic model with the covariance matrix using N-body simulations. We find that the tSZ power spectrum alone prefers σ8 ˜ 0.85 and a large fraction of non-thermal pressure (α0 ˜ 0.2-0.3). The tSZ-WL cross-correlation on the other hand prefers a significantly lower σ8 ˜ 0.6 and low α0 ˜ 0.05. We show that this tension can be mitigated by allowing for a steep slope in the stellar mass-halo mass relation, which would cause a reduction of the gas in low-mass haloes. In such a model, the combined data prefer σ8 ˜ 0.7 and α0 ˜ 0.2, consistent with predictions from hydrodynamical simulations.

  7. Fine mapping of a yield-enhancing QTL cluster associated with transgressive variation in an Oryza sativa x O. rufipogon cross.

    PubMed

    Xie, Xiaobo; Jin, Fengxue; Song, Mi-Hee; Suh, Jung-Pil; Hwang, Hung-Goo; Kim, Yeon-Gyu; McCouch, Susan R; Ahn, Sang-Nag

    2008-03-01

    A high-resolution physical map targeting a cluster of yield-related QTLs on the long arm of rice chromosome 9 has been constructed across a 37.4 kb region containing seven predicted genes. Using a series of BC3F4 nearly isogenic lines (NILs) derived from a cross between the Korean japonica cultivar Hwaseongbyeo and Oryza rufipogon (IRGC 105491), a total of seven QTLs for 1,000-grain weight, spikelets per panicle, grains per panicle, panicle length, spikelet density, heading date and plant height were identified in the cluster (Pregion out-yielded sibling NILs containing Hwaseongbyeo DNA by 14.2-17.7%, and out-yielded the Hwaseongbyeo parent by 16.2-23.7%. While higher yielding plants containing the O. rufipogon introgression were also taller and later than controls, the fact that all seven of the QTLs were co-localized in the same 37.4 kb interval suggests the possibility that a single, pleiotropic gene acting as a major regulator of plant development may control this suite of agronomically important plant phenotypes.

  8. Village-based spatio-temporal cluster analysis of the schistosomiasis risk in the Poyang Lake Region, China.

    PubMed

    Xia, Congcong; Bergquist, Robert; Lynn, Henry; Hu, Fei; Lin, Dandan; Hao, Yuwan; Li, Shizhu; Hu, Yi; Zhang, Zhijie

    2017-03-08

    The Poyang Lake Region, one of the major epidemic sites of schistosomiasis in China, remains a severe challenge. To improve our understanding of the current endemic status of schistosomiasis and to better control the transmission of the disease in the Poyang Lake Region, it is important to analyse the clustering pattern of schistosomiasis and detect the hotspots of transmission risk. Based on annual surveillance data, at the village level in this region from 2009 to 2014, spatial and temporal cluster analyses were conducted to assess the pattern of schistosomiasis infection risk among humans through purely spatial (Local Moran's I, Kulldorff and Flexible scan statistic) and space-time scan statistics (Kulldorff). A dramatic decline was found in the infection rate during the study period, which was shown to be maintained at a low level. The number of spatial clusters declined over time and were concentrated in counties around Poyang Lake, including Yugan, Yongxiu, Nanchang, Xingzi, Xinjian, De'an as well as Pengze, situated along the Yangtze River and the most serious area found in this study. Space-time analysis revealed that the clustering time frame appeared between 2009 and 2011 and the most likely cluster with the widest range was particularly concentrated in Pengze County. This study detected areas at high risk for schistosomiasis both in space and time at the village level from 2009 to 2014 in Poyang Lake Region. The high-risk areas are now more concentrated and mainly distributed at the river inflows Poyang Lake and along Yangtze River in Pengze County. It was assumed that the water projects including reservoirs and a recently breached dyke in this area were partly to blame. This study points out that attempts to reduce the negative effects of water projects in China should focus on the Poyang Lake Region.

  9. Imaging active faulting in a region of distributed deformation from the joint clustering of focal mechanisms and hypocentres: Application to the Azores-western Mediterranean region

    NASA Astrophysics Data System (ADS)

    Custódio, Susana; Lima, Vânia; Vales, Dina; Cesca, Simone; Carrilho, Fernando

    2016-04-01

    The matching between linear trends of hypocentres and fault planes indicated by focal mechanisms (FMs) is frequently used to infer the location and geometry of active faults. This practice works well in regions of fast lithospheric deformation, where earthquake patterns are clear and major structures accommodate the bulk of deformation, but typically fails in regions of slow and distributed deformation. We present a new joint FM and hypocentre cluster algorithm that is able to detect systematically the consistency between hypocentre lineations and FMs, even in regions of distributed deformation. We apply the method to the Azores-western Mediterranean region, with particular emphasis on western Iberia. The analysis relies on a compilation of hypocentres and FMs taken from regional and global earthquake catalogues, academic theses and technical reports, complemented by new FMs for western Iberia. The joint clustering algorithm images both well-known and new seismo-tectonic features. The Azores triple junction is characterised by FMs with vertical pressure (P) axes, in good agreement with the divergent setting, and the Iberian domain is characterised by NW-SE oriented P axes, indicating a response of the lithosphere to the ongoing oblique convergence between Nubia and Eurasia. Several earthquakes remain unclustered in the western Mediterranean domain, which may indicate a response to local stresses. The major regions of consistent faulting that we identify are the mid-Atlantic ridge, the Terceira rift, the Trans-Alboran shear zone and the north coast of Algeria. In addition, other smaller earthquake clusters present a good match between epicentre lineations and FM fault planes. These clusters may signal single active faults or wide zones of distributed but consistent faulting. Mainland Portugal is dominated by strike-slip earthquakes with fault planes coincident with the predominant NNE-SSW and WNW-ESE oriented earthquake lineations. Clusters offshore SW Iberia are

  10. A cross-species bi-clustering approach to identifying conserved co-regulated genes.

    PubMed

    Sun, Jiangwen; Jiang, Zongliang; Tian, Xiuchun; Bi, Jinbo

    2016-06-15

    A growing number of studies have explored the process of pre-implantation embryonic development of multiple mammalian species. However, the conservation and variation among different species in their developmental programming are poorly defined due to the lack of effective computational methods for detecting co-regularized genes that are conserved across species. The most sophisticated method to date for identifying conserved co-regulated genes is a two-step approach. This approach first identifies gene clusters for each species by a cluster analysis of gene expression data, and subsequently computes the overlaps of clusters identified from different species to reveal common subgroups. This approach is ineffective to deal with the noise in the expression data introduced by the complicated procedures in quantifying gene expression. Furthermore, due to the sequential nature of the approach, the gene clusters identified in the first step may have little overlap among different species in the second step, thus difficult to detect conserved co-regulated genes. We propose a cross-species bi-clustering approach which first denoises the gene expression data of each species into a data matrix. The rows of the data matrices of different species represent the same set of genes that are characterized by their expression patterns over the developmental stages of each species as columns. A novel bi-clustering method is then developed to cluster genes into subgroups by a joint sparse rank-one factorization of all the data matrices. This method decomposes a data matrix into a product of a column vector and a row vector where the column vector is a consistent indicator across the matrices (species) to identify the same gene cluster and the row vector specifies for each species the developmental stages that the clustered genes co-regulate. Efficient optimization algorithm has been developed with convergence analysis. This approach was first validated on synthetic data and compared

  11. An external domino effects investment approach to improve cross-plant safety within chemical clusters.

    PubMed

    Reniers, Genserik

    2010-05-15

    Every company situated within a chemical cluster faces the risk of being struck by an escalating accident at one of its neighbouring plants (the so-called external domino effect risks). These cross-plant risks can be reduced or eliminated if neighbouring companies are willing to invest in systems and measures to prevent them. However, since reducing such multi-plant risks does not lead to direct economic benefits, enterprises tend to be reluctant to invest more than needed for meeting minimal legal requirements and they tend to invest without collaborating. The suggested approach in this article indicates what information is required to evaluate the available investment options in external domino effects prevention. To this end, game theory is used as a promising scientific technique to investigate the decision-making process on investments in prevention measures simultaneously involving several plants. The game between two neighbouring chemical plants and their strategic investment behaviour regarding the prevention of external domino effects is described and an illustrative example is provided. Recommendations are formulated to advance cross-plant prevention investments in a two-company cluster. Copyright (c) 2009 Elsevier B.V. All rights reserved.

  12. An imbalance in cluster sizes does not lead to notable loss of power in cross-sectional, stepped-wedge cluster randomised trials with a continuous outcome.

    PubMed

    Kristunas, Caroline A; Smith, Karen L; Gray, Laura J

    2017-03-07

    The current methodology for sample size calculations for stepped-wedge cluster randomised trials (SW-CRTs) is based on the assumption of equal cluster sizes. However, as is often the case in cluster randomised trials (CRTs), the clusters in SW-CRTs are likely to vary in size, which in other designs of CRT leads to a reduction in power. The effect of an imbalance in cluster size on the power of SW-CRTs has not previously been reported, nor what an appropriate adjustment to the sample size calculation should be to allow for any imbalance. We aimed to assess the impact of an imbalance in cluster size on the power of a cross-sectional SW-CRT and recommend a method for calculating the sample size of a SW-CRT when there is an imbalance in cluster size. The effect of varying degrees of imbalance in cluster size on the power of SW-CRTs was investigated using simulations. The sample size was calculated using both the standard method and two proposed adjusted design effects (DEs), based on those suggested for CRTs with unequal cluster sizes. The data were analysed using generalised estimating equations with an exchangeable correlation matrix and robust standard errors. An imbalance in cluster size was not found to have a notable effect on the power of SW-CRTs. The two proposed adjusted DEs resulted in trials that were generally considerably over-powered. We recommend that the standard method of sample size calculation for SW-CRTs be used, provided that the assumptions of the method hold. However, it would be beneficial to investigate, through simulation, what effect the maximum likely amount of inequality in cluster sizes would be on the power of the trial and whether any inflation of the sample size would be required.

  13. A WISE Survey of New Star Clusters in the Central Plane Region of the Milky Way

    NASA Astrophysics Data System (ADS)

    Ryu, Jinhyuk; Lee, Myung Gyoon

    2018-04-01

    We present the discovery of new star clusters in the central plane region (| l| < 30^\\circ and | b| < 6^\\circ ) of the Milky Way. In order to overcome the extinction problem and the spatial limit of previous surveys, we use the Wide-field Infrared Survey Explorer (WISE) data to find clusters. We also use other infrared survey data in the archive for additional analysis. We find 923 new clusters, of which 202 clusters are embedded clusters. These clusters are concentrated toward the Galactic plane and show a symmetric distribution with respect to the Galactic latitude. The embedded clusters show a stronger concentration to the Galactic plane than the nonembedded clusters. The new clusters are found more in the first Galactic quadrant, while previously known clusters are found more in the fourth Galactic quadrant. The spatial distribution of the combined sample of known clusters and new clusters is approximately symmetric with respect to the Galactic longitude. We estimate reddenings, distances, and relative ages of the 15 class A clusters using theoretical isochrones. Ten of them are relatively old (age >800 Myr) and five are young (age ≈4 Myr).

  14. A distal earthquake cluster concurrent with the 2006 explosive eruption of Augustine Volcano, Alaska

    USGS Publications Warehouse

    Fisher, M.A.; Ruppert, N.A.; White, R.A.; Wilson, Frederic H.; Comer, D.; Sliter, R.W.; Wong, F.L.

    2009-01-01

    Clustered earthquakes located 25??km northeast of Augustine Volcano began about 6??months before and ceased soon after the volcano's 2006 explosive eruption. This distal seismicity formed a dense cluster less than 5??km across, in map view, and located in depth between 11??km and 16??km. This seismicity was contemporaneous with sharply increased shallow earthquake activity directly below the volcano's vent. Focal mechanisms for five events within the distal cluster show strike-slip fault movement. Cluster seismicity best defines a plane when it is projected onto a northeast-southwest cross section, suggesting that the seismogenic fault strikes northwest. However, two major structural trends intersect near Augustine Volcano, making it difficult to put the seismogenic fault into a regional-geologic context. Specifically, interpretation of marine multichannel seismic-reflection (MCS) data shows reverse faults, directly above the seismicity cluster, that trend northeast, parallel to the regional geologic strike but perpendicular to the fault suggested by the clustered seismicity. The seismogenic fault could be a reactivated basement structure.

  15. Characterizing the W40 Cluster Region with the UKIDSS Galactic Plane Survey

    NASA Astrophysics Data System (ADS)

    Yu, Ka Chun; Shuping, Ralph

    2018-01-01

    W40 is a region of thermal radio continuum emission in the Aquila Rift, and is one of only a few high-mass star forming regions within 1 kpc of the Sun. We use the Galactic Plane Survey from the UKIDDS Data Release 10 in JHK to study the stellar population in a 30' x 30' field centered on the W40 star-forming region. With imaging deeper than previous surveys (down to a depth of K=18), we identify ~1500 stars with K-band excess that are likely young stars with protostellar disks (Class II-III), more than has been found in previous surveys of this region. We use the NIR photometry of ~50,000 stars to create a high resolution 0.5' optical extinction map, which is used in conjunction with nearby control fields to assess contamination by background sources. Like in previous studies, we find an embedded cluster of reddened sources centered on the handful of late-O/early-B type stars at the center of W40. We fit their spatial distribution using a 2D gaussian profile with $\\sigma$ ~ 1' (0.37 pc at a distance of 440 pc), and a central stellar density of 510 stars/pc^2. After removing foreground stars, we identify 217 total stars within $3\\sigma$ of the cluster center, of which ~100 have K-band excess indicative of Class II-III YSOs, consistent with previous work. We discuss possible background contamination as well as the spatial distribution of young stars throughout the region.

  16. Effect of dose and size on defect engineering in carbon cluster implanted silicon wafers

    NASA Astrophysics Data System (ADS)

    Okuyama, Ryosuke; Masada, Ayumi; Shigematsu, Satoshi; Kadono, Takeshi; Hirose, Ryo; Koga, Yoshihiro; Okuda, Hidehiko; Kurita, Kazunari

    2018-01-01

    Carbon-cluster-ion-implanted defects were investigated by high-resolution cross-sectional transmission electron microscopy toward achieving high-performance CMOS image sensors. We revealed that implantation damage formation in the silicon wafer bulk significantly differs between carbon-cluster and monomer ions after implantation. After epitaxial growth, small and large defects were observed in the implanted region of carbon clusters. The electron diffraction pattern of both small and large defects exhibits that from bulk crystalline silicon in the implanted region. On the one hand, we assumed that the silicon carbide structure was not formed in the implanted region, and small defects formed because of the complex of carbon and interstitial silicon. On the other hand, large defects were hypothesized to originate from the recrystallization of the amorphous layer formed by high-dose carbon-cluster implantation. These defects are considered to contribute to the powerful gettering capability required for high-performance CMOS image sensors.

  17. Lack of small-scale clustering in 21-cm intensity maps crossed with 2dF galaxy densities at z ~ 0.08

    NASA Astrophysics Data System (ADS)

    Anderson, Christopher; Luciw, Nicholas; Li, Yi-Chao; Kuo, Cheng-Yu; Yadav, Jaswant; Masui, Kiyoshi; Chang, Tzu-Ching; Chen, Xuelei; Oppermann, Niels; Pen, Ue-Li; Timbie, Peter T.

    2017-06-01

    I report results from 21-cm intensity maps acquired from the Parkes radio telescope and cross-correlated with galaxy maps from the 2dF galaxy survey. The data span the redshift range 0.057cross-power spectrum exhibits a dip in power at small scales, around k~1.0 hMpc^-1, compared to the 2dF auto-power spectrum and the theoretical dark matter power spectrum. This indicates either a lack of clustering of neutral hydrogen (HI) at small scales or a small correlation coefficient between optical galaxies and HI, or some combination of the two. A lack of small scale HI clustering would be qualitatively similar to measurements of HI-selected galaxy clustering from the HIPASS and ALFALFA surveys at slightly lower redshifts.

  18. 40 CFR 81.66 - Southeast Minnesota-La Crosse (Wisconsin) Interstate Air Quality Control Region.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 18 2012-07-01 2012-07-01 false Southeast Minnesota-La Crosse... PLANNING PURPOSES Designation of Air Quality Control Regions § 81.66 Southeast Minnesota-La Crosse (Wisconsin) Interstate Air Quality Control Region. The Southeast Minnesota-La Crosse (Wisconsin) Interstate...

  19. 40 CFR 81.66 - Southeast Minnesota-La Crosse (Wisconsin) Interstate Air Quality Control Region.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 17 2011-07-01 2011-07-01 false Southeast Minnesota-La Crosse... PLANNING PURPOSES Designation of Air Quality Control Regions § 81.66 Southeast Minnesota-La Crosse (Wisconsin) Interstate Air Quality Control Region. The Southeast Minnesota-La Crosse (Wisconsin) Interstate...

  20. 40 CFR 81.66 - Southeast Minnesota-La Crosse (Wisconsin) Interstate Air Quality Control Region.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 18 2013-07-01 2013-07-01 false Southeast Minnesota-La Crosse... PLANNING PURPOSES Designation of Air Quality Control Regions § 81.66 Southeast Minnesota-La Crosse (Wisconsin) Interstate Air Quality Control Region. The Southeast Minnesota-La Crosse (Wisconsin) Interstate...

  1. 40 CFR 81.66 - Southeast Minnesota-La Crosse (Wisconsin) Interstate Air Quality Control Region.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 18 2014-07-01 2014-07-01 false Southeast Minnesota-La Crosse... PLANNING PURPOSES Designation of Air Quality Control Regions § 81.66 Southeast Minnesota-La Crosse (Wisconsin) Interstate Air Quality Control Region. The Southeast Minnesota-La Crosse (Wisconsin) Interstate...

  2. 40 CFR 81.66 - Southeast Minnesota-La Crosse (Wisconsin) Interstate Air Quality Control Region.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 17 2010-07-01 2010-07-01 false Southeast Minnesota-La Crosse... PLANNING PURPOSES Designation of Air Quality Control Regions § 81.66 Southeast Minnesota-La Crosse (Wisconsin) Interstate Air Quality Control Region. The Southeast Minnesota-La Crosse (Wisconsin) Interstate...

  3. DMRT gene cluster analysis in the platypus: new insights into genomic organization and regulatory regions.

    PubMed

    El-Mogharbel, Nisrine; Wakefield, Matthew; Deakin, Janine E; Tsend-Ayush, Enkhjargal; Grützner, Frank; Alsop, Amber; Ezaz, Tariq; Marshall Graves, Jennifer A

    2007-01-01

    We isolated and characterized a cluster of platypus DMRT genes and compared their arrangement, location, and sequence across vertebrates. The DMRT gene cluster on human 9p24.3 harbors, in order, DMRT1, DMRT3, and DMRT2, which share a DM domain. DMRT1 is highly conserved and involved in sexual development in vertebrates, and deletions in this region cause sex reversal in humans. Sequence comparisons of DMRT genes between species have been valuable in identifying exons, control regions, and conserved nongenic regions (CNGs). The addition of platypus sequences is expected to be particularly valuable, since monotremes fill a gap in the vertebrate genome coverage. We therefore isolated and fully sequenced platypus BAC clones containing DMRT3 and DMRT2 as well as DMRT1 and then generated multispecies alignments and ran prediction programs followed by experimental verification to annotate this gene cluster. We found that the three genes have 58-66% identity to their human orthologues, lie in the same order as in other vertebrates, and colocate on 1 of the 10 platypus sex chromosomes, X5. We also predict that optimal annotation of the newly sequenced platypus genome will be challenging. The analysis of platypus sequence revealed differences in structure and sequence of the DMRT gene cluster. Multispecies comparison was particularly effective for detecting CNGs, revealing several novel potential regulatory regions within DMRT3 and DMRT2 as well as DMRT1. RT-PCR indicated that platypus DMRT1 and DMRT3 are expressed specifically in the adult testis (and not ovary), but DMRT2 has a wider expression profile, as it does for other mammals. The platypus DMRT1 expression pattern, and its location on an X chromosome, suggests an involvement in monotreme sexual development.

  4. Alpha Cluster Structure in 16O

    NASA Astrophysics Data System (ADS)

    Dias Rodrigues, Márcia Regina; Borello-Lewin, Thereza; Miyake, Hideaki; Cappuzzello, Francesco; Cavallaro, Manuela; Duarte, José Luciano Miranda; Lima Rodrigues, Cleber; de Souza, Marco Antonio; Horodynski-Matsushigue, Brighitta; Cunsolo, Angelo; Foti, Antonio; Mitsuo Ukita, Gilberto; Neto de Faria, Pedro; Agodi, Clementina; De Napoli, Marzio; Nicolosi, Dario; Bondì, Dario; Carbone, Diana; Tropea, Stefania

    2014-03-01

    The main purpose of the present work is the investigation of the α-cluster phenomenon in 16O. The 12C(6Li,d)16O reaction was measured at a bombarding energy of 25.5 MeV employing the São Paulo Pelletron-Enge-Spectrograph facility and the nuclear emulsion detection technique. Resonant states around 4α threshold were measured and an energy resolution of 15 keV allows to define states previously unresolved. The angular distributions of the absolute cross sections were determined in a range of 4-40 degree in the center of mass system. The upper limit for the resonance widths was obtained, indicating that the a cluster structure information in this region should be revised.

  5. Observational Study of Ion Diffusion Region tailward of the Cusp: Polar and Cluster Observations in 1998-2008

    NASA Astrophysics Data System (ADS)

    Muzamil, F. M.; Farrugia, C. J.; Torbert, R. B.; Argall, M. R.; Wang, S.

    2015-12-01

    Asymmetries in plasma density and the presence of a guide field significantly alter the structure of the ion diffusion region (IDR) in symmetric, collisionless reconnection. These features have been shown by numerical simulations under moderate density asymmetries (~10), and theoretical analyses. However, very few studies have addressed these issues with in-situ observations. We have compiled a collection of Cluster and Polar crossings of the high-latitude magnetopause poleward of the cusp under northward interplanetary magnetic field in the years 1998-2008 when signatures of reconnection inside the IDR are observed. They encompass a wide range of density asymmetries (~10 to 1000), magnetic field asymmetries (~0.2 to 0.9), and guide fields (~10 to ~60 %). In this dedicated observational study, we target the following topics: (1) The alteration of the structure of the IDR -- i.e., its width, the non-colocation of stagnation and X-lines, jet outflow speed, and biasing of the reconnection outflow jet toward the magnetosphere -- as a function of increasing density asymmetry, and (2) the diamagnetic drift of the X-line. Further, focusing on IDR crossings during plasma flow reversals and/or near-simultaneous crossings on either side of the X-line by two spacecraft under steady ambient conditions, we report on the contrast in the Hall fields and the plasma behavior on the sunward versus the tailward sides of the X-line in its dependence on the strength of the guide field.

  6. Defective functional connectivity between posterior hypothalamus and regions of the diencephalic-mesencephalic junction in chronic cluster headache.

    PubMed

    Ferraro, Stefania; Nigri, Anna; Bruzzone, Maria Grazia; Brivio, Luca; Proietti Cecchini, Alberto; Verri, Mattia; Chiapparini, Luisa; Leone, Massimo

    2018-01-01

    Objective We tested the hypothesis of a defective functional connectivity between the posterior hypothalamus and diencephalic-mesencephalic regions in chronic cluster headache based on: a) clinical and neuro-endocrinological findings in cluster headache patients; b) neuroimaging findings during cluster headache attacks; c) neuroimaging findings in drug-refractory chronic cluster headache patients improved after successful deep brain stimulation. Methods Resting state functional magnetic resonance imaging, associated with a seed-based approach, was employed to investigate the functional connectivity of the posterior hypothalamus in chronic cluster headache patients (n = 17) compared to age and sex-matched healthy subjects (n = 16). Random-effect analyses were performed to study differences between patients and controls in ipsilateral and contralateral-to-the-pain posterior hypothalamus functional connectivity. Results Cluster headache patients showed an increased functional connectivity between the ipsilateral posterior hypothalamus and a number of diencephalic-mesencephalic structures, comprising ventral tegmental area, dorsal nuclei of raphe, and bilateral substantia nigra, sub-thalamic nucleus, and red nucleus ( p < 0.005 FDR-corrected vs . control group). No difference between patients and controls was found comparing the contralateral hypothalami. Conclusions The observed deranged functional connectivity between the posterior ipsilateral hypothalamus and diencephalic-mesencephalic regions in chronic cluster headache patients mainly involves structures that are part of (i.e. ventral tegmental area, substantia nigra) or modulate (dorsal nuclei of raphe, sub-thalamic nucleus) the midbrain dopaminergic systems. The midbrain dopaminergic systems could play a role in cluster headache pathophysiology and in particular in the chronicization process. Future studies are needed to better clarify if this finding is specific to cluster headache or if it

  7. Prediction of hot regions in protein-protein interaction by combining density-based incremental clustering with feature-based classification.

    PubMed

    Hu, Jing; Zhang, Xiaolong; Liu, Xiaoming; Tang, Jinshan

    2015-06-01

    Discovering hot regions in protein-protein interaction is important for drug and protein design, while experimental identification of hot regions is a time-consuming and labor-intensive effort; thus, the development of predictive models can be very helpful. In hot region prediction research, some models are based on structure information, and others are based on a protein interaction network. However, the prediction accuracy of these methods can still be improved. In this paper, a new method is proposed for hot region prediction, which combines density-based incremental clustering with feature-based classification. The method uses density-based incremental clustering to obtain rough hot regions, and uses feature-based classification to remove the non-hot spot residues from the rough hot regions. Experimental results show that the proposed method significantly improves the prediction performance of hot regions. Copyright © 2015 Elsevier Ltd. All rights reserved.

  8. Probing electronic wave functions of sodium-doped clusters: Dyson orbitals, anisotropy parameters, and ionization cross-sections

    DOE PAGES

    Gunina, Anastasia O.; Krylov, Anna I.

    2016-11-14

    We apply high-level ab initio methods to describe the electronic structure of small clusters of ammonia and dimethylether (DME) doped with sodium, which provide a model for solvated electrons. We investigate the effect of the solvent and cluster size on the electronic states. We consider both energies and properties, with a focus on the shape of the electronic wave function and the related experimental observables such as photoelectron angular distributions. The central quantity in modeling photoionization experiments is the Dyson orbital, which describes the difference between the initial N-electron and final (N-1)-electron states of a system. Dyson orbitals enter themore » expression of the photoelectron matrix element, which determines total and partial photoionization cross-sections. We compute Dyson orbitals for the Na(NH3)n and Na(DME)m clusters using correlated wave functions (obtained with equation-of-motion coupled-cluster model for electron attachment with single and double substitutions) and compare them with more approximate Hartree-Fock and Kohn-Sham orbitals. As a result, we also analyze the effect of correlation and basis sets on the shapes of Dyson orbitals and the experimental observables.« less

  9. HST-WFPC2 Observations of the Star Clusters in the Giant H II Regions of M33

    NASA Astrophysics Data System (ADS)

    Lee, Myung Gyoon; Park, Hong Soo; Kim, Sang Chul; Waller, William H.; Parker, Joel Wm.; Malumuth, Eliot M.; Hodge, Paul W.

    We present a photometric study of the stars in ionizing star clusters embedded in several giant H II regions of M33 (CC93, IC 142, NGC 595, MA2, NGC 604 and NGC 588). Our photometry is based on the HST-WFPC2 images of these clusters. Color-magnitude diagrams and color-color diagrams of these clusters are obtained and are used for estimating the reddenings and ages of the clusters. The luminosity functions (LFs) and initial mass functions (IMFs) of the massive stars in these clusters are also derived. The slopes of the IMFs range from Γ = -0.5 to -2.1. Interestingly, it is found that the IMFs get steeper with increasing galactocentric distance and with decreasing [O/H] abundance.

  10. Spatiotemporal earthquake clusters along the North Anatolian fault zone offshore Istanbul

    USGS Publications Warehouse

    Bulut, Fatih; Ellsworth, William L.; Bohnhoff, Marco; Aktar, Mustafa; Dresen, Georg

    2011-01-01

    We investigate earthquakes with similar waveforms in order to characterize spatiotemporal microseismicity clusters within the North Anatolian fault zone (NAFZ) in northwest Turkey along the transition between the 1999 ??zmit rupture zone and the Marmara Sea seismic gap. Earthquakes within distinct activity clusters are relocated with cross-correlation derived relative travel times using the double difference method. The spatiotemporal distribution of micro earthquakes within individual clusters is resolved with relative location accuracy comparable to or better than the source size. High-precision relative hypocenters define the geometry of individual fault patches, permitting a better understanding of fault kinematics and their role in local-scale seismotectonics along the region of interest. Temporal seismic sequences observed in the eastern Sea of Marmara region suggest progressive failure of mostly nonoverlapping areas on adjacent fault patches and systematic migration of microearthquakes within clusters during the progressive failure of neighboring fault patches. The temporal distributions of magnitudes as well as the number of events follow swarmlike behavior rather than a mainshock/aftershock pattern.

  11. Thrombopoietin contributes to the formation and the maintenance of hematopoietic progenitor-containing cell clusters in the aorta-gonad-mesonephros region.

    PubMed

    Harada, Kaho; Nobuhisa, Ikuo; Anani, Maha; Saito, Kiyoka; Taga, Tetsuya

    2017-07-01

    In the midgestation mouse embryo, hematopoietic cell clusters containing hematopoietic stem/progenitor cells arise in the aorta-gonad-mesonephros (AGM) region. We have previously reported that forced expression of the Sox17 transcription factor in CD45 low c-Kit high AGM cells, which are the hematopoietic cellular component of the cell clusters, and subsequent coculture with OP9 stromal cells in the presence of three cytokines, stem cell factor (SCF), interleukin-3 (IL-3), and thrombopoietin (TPO), led to the formation and the maintenance of cell clusters with cells at an undifferentiated state in vitro. In this study, we investigated the role of each cytokine in the formation of hematopoietic cell clusters. We cultured Sox17-transduced AGM cells with each of the 7 possible combinations of the three cytokines. The size and the number of Sox17-transduced cell clusters in the presence of TPO, either alone or in combination, were comparable to that observed with the complete set of the three cytokines. Expression of TPO receptor, c-Mpl was almost ubiquitously expressed and maintained in Sox17-transduced hematopoietic cell clusters. In addition, the expression level of c-Mpl was highest in the CD45 low c-Kit high cells among the Sox17-transduced cell clusters. Moreover, c-Mpl protein was highly expressed in the intra-aortic hematopoietic cell clusters in comparison with endothelial cells of dorsal aorta. Finally, stimulation of the endothelial cells prepared from the AGM region by TPO induced the production of hematopoietic cells. These results suggest that TPO contributes to the formation and the maintenance of hematopoietic cell clusters in the AGM region. Copyright © 2017 Elsevier Ltd. All rights reserved.

  12. Merging Clusters, Cluster Outskirts, and Large Scale Filaments

    NASA Astrophysics Data System (ADS)

    Randall, Scott; Alvarez, Gabriella; Bulbul, Esra; Jones, Christine; Forman, William; Su, Yuanyuan; Miller, Eric D.; Bourdin, Herve; Scott Randall

    2018-01-01

    Recent X-ray observations of the outskirts of clusters show that entropy profiles of the intracluster medium (ICM) generally flatten and lie below what is expected from purely gravitational structure formation near the cluster's virial radius. Possible explanations include electron/ion non-equilibrium, accretion shocks that weaken during cluster formation, and the presence of unresolved cool gas clumps. Some of these mechanisms are expected to correlate with large scale structure (LSS), such that the entropy is lower in regions where the ICM interfaces with LSS filaments and, presumably, the warm-hot intergalactic medium (WHIM). Major, binary cluster mergers are expected to take place at the intersection of LSS filaments, with the merger axis initially oriented along a filament. We present results from deep X-ray observations of the virialization regions of binary, early-stage merging clusters, including a possible detection of the dense end of the WHIM along a LSS filament.

  13. Disruption of the Globular Cluster Pal 5

    NASA Technical Reports Server (NTRS)

    Miller, R. H.; Smith, B. F.; Cuzzi, Jeffrey N. (Technical Monitor)

    1995-01-01

    Orbit calculations suggest that the sparse globular cluster, Pal 5, will pass within 7 kpc of the Galactic center the next time it crosses the plane, where it might be destroyed by tidal stresses. We study this problem, treating Pal 5 as a self-consistent dynamical system orbiting through an external potential that represents the Galaxy. The first part of the problem is to find suitable analytic approximations to the Galactic potential. They must be valid in all regions the cluster is likely to explore. Observed velocity and positional data for Pal 5 are used as initial conditions to determine the orbit. Methods we used for a different problem some 12 years ago have been adapted to this problem. Three experiments have been run, with M/L= 1, 3, and 10, for the cluster model. The cluster blew up shortly after passing through the Galactic plane (about 130 Myrs after the beginning of the run) with M/L=1. At M/L = 3 and 10 the cluster survived, although it got quite a kick in the fundamental mode on passing through the plane. But the fundamental mode oscillation died out in a couple of oscillation cycles at M/L=10. Pal 5 will probably be destroyed on its next crossing of the Galactic plane if M/L=1, but it can survive (albeit with fairly heavy damage) if NI/L=3. We haven't tried to trap the mass limits more closely than that. Pal 5 comes through pretty well unscathed at M/L=10. An interesting follow-up experiment would be to back the cluster up along its orbit to look at its previous passage through the Galactic plane, to see what kind of object it might have been at earlier times.

  14. Submegabase Clusters of Unstable Tandem Repeats Unique to the Tla Region of Mouse T Haplotypes

    PubMed Central

    Uehara, H.; Ebersole, T.; Bennett, D.; Artzt, K.

    1990-01-01

    We describe here the identification and genomic organization of mouse t haplotype-specific elements (TSEs) 7.8 and 5.8 kb in length. The TSEs exist as submegabase-long clusters of tandem repeats localized in the Tla region of the major histocompatibility complex of all t haplotype chromosomes examined. In contrast, no such clusters were detected among 12 inbred strains of Mus musculus and other Mus species; thus, clusters of TSEs represent the first absolutely qualitative difference between t haplotypes and wild-type chromosomes. Pulsed field gel electrophoresis shows that the number of clusters, and the number of repeats in each cluster are extremely variable. Dramatic quantitative differences of TSEs uniquely distinguish every independent t haplotype from any other. The complete nucleotide sequence of one 7.8-kb TSE reveals significant homology to the ETn (a major transcript in the early embryo of the mouse), and some homologies to intracisternal A-particles and the mammary tumor virus env gene. Apart from the diagnostic relevance to t haplotypes, evolutionary and functional significances are discussed with respect to chromosome structure and genetic recombination. PMID:2076812

  15. Monitoring evolving urban cluster systems using DMSP/OLS nighttime light data: a case study of the Yangtze River Delta region, China

    NASA Astrophysics Data System (ADS)

    Wang, Zhao; Yang, Shan; Wang, Shuguang; Shen, Yan

    2017-10-01

    The assessment of the dynamic urban structure has been affected by lack of timely and accurate spatial information for a long period, which has hindered the measurements of structural continuity at the macroscale. Defense meteorological satellite program's operational linescan system (DMSP/OLS) nighttime light (NTL) data provide an ideal source for urban information detection with a long-time span, short-time interval, and wide coverage. In this study, we extracted the physical boundaries of urban clusters from corrected NTL images and quantitatively analyzed the structure of the urban cluster system based on rank-size distribution, spatial metrics, and Mann-Kendall trend test. Two levels of urban cluster systems in the Yangtze River Delta region (YRDR) were examined. We found that (1) in the entire YRDR, the urban cluster system showed a periodic process, with a significant trend of even distribution before 2007 but an unequal growth pattern after 2007, and (2) at the metropolitan level, vast disparities exist in four metropolitan areas for the fluctuations of Pareto's exponent, the speed of cluster expansion, and the dominance of core cluster. The results suggest that the extracted urban cluster information from NTL data effectively reflect the evolving nature of regional urbanization, which in turn can aid in the planning of cities and help achieve more sustainable regional development.

  16. Photoabsorption cross section of acetylene in the EUV region

    NASA Technical Reports Server (NTRS)

    Wu, C. Y. R.; Judge, D. L.

    1985-01-01

    The measurement of the absolute photoabsorption cross sections of C2H2 in the 175-740 A region by means of a double ionization chamber is reported. The continuum background source is the synchrotron radiation emitted by the Wisconsin 240 MeV electron storage ring. It is found that the cross sections range from 2 to a maximum of 36 Mb. Two new Rydberg series are identified and the cross section data are applied in the analysis of various sum rules. From the rules, it is shown that the data of C2H2 in the 580-1088 A range may be too low, while the measured ionization transition moment may be too high.

  17. Delay Times From Clustered Multi-Channel Cross Correlation and Simulated Annealing

    NASA Astrophysics Data System (ADS)

    Creager, K. C.; Sambridge, M. S.

    2004-12-01

    Several techniques exist to estimate relative delay times of seismic phases based on the assumption that the waveforms observed at several stations can be expressed as a common waveform that has been time shifted and distorted by random uncorrelated noise. We explore the more general problem of estimating the relative delay times for regional or even global distributions of seismometers in cases where waveforms vary systematically across the array. The estimation of relative delay times is formulated as a global optimization of the weighted sum of squares of cross correlations of each seismogram pair evaluated at the corresponding difference in their relative delay times. As there are many local minima in this penalty function, a simulated annealing algorithm is used to obtain a solution. The weights depend strongly on the separation distance among seismogram pairs as well as a measure of the similarity of waveforms. Thus, seismograph pairs that are physically close to each other and have similar waveforms are expected to be well aligned while those with dissimilar waveforms or large separation distances are severely down-weighted and thus need not be well aligned. As a result noisy seismograms, which are not similar to other seismograms, are down-weighted so they do not adversely effect the relative delay times of other seismograms. Finally, natural clusters of seismograms are determined from the weight matrix. Examples of aligning a few hundred P and PKP waveforms from a broadband global array and from a mixed broadband and short-period continental-scale array will be shown. While this method has applications in many situations, it may be especially useful for arrays such as the EarthScope Bigfoot Array.

  18. Cross-scale analysis of cluster correspondence using different operational neighborhoods

    NASA Astrophysics Data System (ADS)

    Lu, Yongmei; Thill, Jean-Claude

    2008-09-01

    Cluster correspondence analysis examines the spatial autocorrelation of multi-location events at the local scale. This paper argues that patterns of cluster correspondence are highly sensitive to the definition of operational neighborhoods that form the spatial units of analysis. A subset of multi-location events is examined for cluster correspondence if they are associated with the same operational neighborhood. This paper discusses the construction of operational neighborhoods for cluster correspondence analysis based on the spatial properties of the underlying zoning system and the scales at which the zones are aggregated into neighborhoods. Impacts of this construction on the degree of cluster correspondence are also analyzed. Empirical analyses of cluster correspondence between paired vehicle theft and recovery locations are conducted on different zoning methods and across a series of geographic scales and the dynamics of cluster correspondence patterns are discussed.

  19. The HectoMAP Cluster Survey. II. X-Ray Clusters

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sohn, Jubee; Chon, Gayoung; Bohringer, Hans

    Here, we apply a friends-of-friends algorithm to the HectoMAP redshift survey and cross-identify associated X-ray emission in the ROSAT All-Sky Survey data (RASS). The resulting flux-limited catalog of X-ray cluster surveys is complete to a limiting flux of ~3 × 10 –13 erg s –1 cm –2 and includes 15 clusters (7 newly discovered) with redshifts z ≤ 0.4. HectoMAP is a dense survey (~1200 galaxies deg –2) that provides ~50 members (median) in each X-ray cluster. We provide redshifts for the 1036 cluster members. Subaru/Hyper Suprime-Cam imaging covers three of the X-ray systems and confirms that they are impressivemore » clusters. The HectoMAP X-ray clusters have an L X–σ cl scaling relation similar to that of known massive X-ray clusters. The HectoMAP X-ray cluster sample predicts ~12,000 ± 3000 detectable X-ray clusters in RASS to the limiting flux, comparable with previous estimates.« less

  20. The HectoMAP Cluster Survey. II. X-Ray Clusters

    DOE PAGES

    Sohn, Jubee; Chon, Gayoung; Bohringer, Hans; ...

    2018-03-10

    Here, we apply a friends-of-friends algorithm to the HectoMAP redshift survey and cross-identify associated X-ray emission in the ROSAT All-Sky Survey data (RASS). The resulting flux-limited catalog of X-ray cluster surveys is complete to a limiting flux of ~3 × 10 –13 erg s –1 cm –2 and includes 15 clusters (7 newly discovered) with redshifts z ≤ 0.4. HectoMAP is a dense survey (~1200 galaxies deg –2) that provides ~50 members (median) in each X-ray cluster. We provide redshifts for the 1036 cluster members. Subaru/Hyper Suprime-Cam imaging covers three of the X-ray systems and confirms that they are impressivemore » clusters. The HectoMAP X-ray clusters have an L X–σ cl scaling relation similar to that of known massive X-ray clusters. The HectoMAP X-ray cluster sample predicts ~12,000 ± 3000 detectable X-ray clusters in RASS to the limiting flux, comparable with previous estimates.« less

  1. Extended phenotype and clinical subgroups in unilateral Meniere disease: A cross-sectional study with cluster analysis.

    PubMed

    Frejo, L; Martin-Sanz, E; Teggi, R; Trinidad, G; Soto-Varela, A; Santos-Perez, S; Manrique, R; Perez, N; Aran, I; Almeida-Branco, M S; Batuecas-Caletrio, A; Fraile, J; Espinosa-Sanchez, J M; Perez-Guillen, V; Perez-Garrigues, H; Oliva-Dominguez, M; Aleman, O; Benitez, J; Perez, P; Lopez-Escamez, J A

    2017-12-01

    To define clinical subgroups by cluster analysis in patients with unilateral Meniere disease (MD) and to compare them with the clinical subgroups found in bilateral MD. A cross-sectional study with a two-step cluster analysis. A tertiary referral multicenter study. Nine hundred and eighty-eight adult patients with unilateral MD. best predictors to define clinical subgroups with potential different aetiologies. We established five clusters in unilateral MD. Group 1 is the most frequently found, includes 53% of patients, and it is defined as the sporadic, classic MD without migraine and without autoimmune disorder (AD). Group 2 is found in 8% of patients, and it is defined by hearing loss, which antedates the vertigo episodes by months or years (delayed MD), without migraine or AD in most of cases. Group 3 involves 13% of patients, and it is considered familial MD, while group 4, which includes 15% of patients, is linked to the presence of migraine in all cases. Group 5 is found in 11% of patients and is defined by a comorbid AD. We found significant differences in the distribution of AD in clusters 3, 4 and 5 between patients with uni- and bilateral MD. Cluster analysis defines clinical subgroups in MD, and it extends the phenotype beyond audiovestibular symptoms. This classification will help to improve the phenotyping in MD and facilitate the selection of patients for randomised clinical trials. © 2017 John Wiley & Sons Ltd.

  2. Cluster bulleticity

    NASA Astrophysics Data System (ADS)

    Massey, Richard; Kitching, Thomas; Nagai, Daisuke

    2011-05-01

    The unique properties of dark matter are revealed during collisions between clusters of galaxies, such as the bullet cluster (1E 0657-56) and baby bullet (MACS J0025-12). These systems provide evidence for an additional, invisible mass in the separation between the distributions of their total mass, measured via gravitational lensing, and their ordinary 'baryonic' matter, measured via its X-ray emission. Unfortunately, the information available from these systems is limited by their rarity. Constraints on the properties of dark matter, such as its interaction cross-section, are therefore restricted by uncertainties in the individual systems' impact velocity, impact parameter and orientation with respect to the line of sight. Here we develop a complementary, statistical measurement in which every piece of substructure falling into every massive cluster is treated as a bullet. We define 'bulleticity' as the mean separation between dark matter and ordinary matter, and we measure the signal in hydrodynamical simulations. The phase space of substructure orbits also exhibits symmetries that provide an equivalent control test. Any detection of bulleticity in real data would indicate a difference in the interaction cross-sections of baryonic and dark matter that may rule out hypotheses of non-particulate dark matter that are otherwise able to model individual systems. A subsequent measurement of bulleticity could constrain the dark matter cross-section. Even with conservative estimates, the existing Hubble Space Telescope archive should yield an independent constraint tighter than that from the bullet cluster. This technique is then trivially extendable to and benefits enormously from larger, future surveys.

  3. Winter precipitation forecast in the European and Mediterranean regions using cluster analysis

    NASA Astrophysics Data System (ADS)

    Molnos, S.

    2017-12-01

    The European and Mediterranean climates are sensitive to large-scale circulation of the atmosphere andocean making it difficult to forecast precipitation or temperature on seasonal time-scales. In addition, theMediterranean region has been identified as a hotspot for climate change and already today a drying in theMediterranean region is observed.Thus, it is critically important to predict seasonal droughts as early as possible such that water managersand stakeholders can mitigate impacts.We developed a novel cluster-based forecast method to empirically predict winter's precipitationanomalies in European and Mediterranean regions using precursors in autumn. This approach does notonly utilizes the amplitude but also the pattern of the precursors in generating the forecast.Using a toy model we show that it achieves a better forecast skill than more traditional regression models. Furthermore, we compare our algorithm with dynamic forecast models demonstrating that our prediction method performs better in terms of time and pattern correlation in the Mediterranean and European regions.

  4. Metal concentration and X-ray cool spectral component in the central region of the Centaurus cluster of galaxies

    NASA Technical Reports Server (NTRS)

    Fukazawa, Yasushi; Ohashi, Takaya; Fabian, Andrew C.; Canizares, Claude R.; Ikebe, Yasushi; Makishima, Kazuo; Mushotzky, Richard F.; Yamashita, Koujun

    1994-01-01

    Spatially resolved energy spectra in the energy range 0.5-10 keV have been measured for the Centaurus cluster of galaxies with Advanced Satellite for Cosmology and Astrophysics (ASCA). Within 10 min (200 kpc) from the cluster center, the helium-like iron K emission line exhibits a dramatic increase toward the center rising from an equivalent width approximately 500 eV to approximately 1500 eV corresponding to an abundance change from 0.3 to 1.0 solar. The presence of strong iron L lines indicates an additional cool component (kT approximately 1 keV) within 10 min from the center. The cool component requires absorption in excess of the galactic value and this excess absorption increases towards the central region of the cluster. In the surrounding region with radius greater than 10 min, the spectra are well described by a single temperature thermal model with kT approximately 4 keV and spatially uniform abundances at about 0.3-0.4 times solar. The detection of metal-rich hot and cool gas in the cluster center implies a complex nature of the central cluster gas which is likely to be related to the presence of the central cD galaxy NGC 4696.

  5. Search of extended gamma-ray emission from the Virgo Galaxy cluster with Fermi-Lat

    DOE PAGES

    Ackermann, M.; Ajello, M.; Albert, A.; ...

    2015-10-20

    Galaxy clusters are one of the prime sites to search for dark matter (DM) annihilation signals. Depending on the substructure of the DM halo of a galaxy cluster and the cross sections for DM annihilation channels, these signals might be detectable by the latest generation of γ-ray telescopes. We use three years of Fermi-Large Area Telescope data, which are the most suitable for searching for very extended emission in the vicinity of the nearby Virgo galaxy cluster. Our analysis reveals statistically significant extended emission which can be well characterized by a uniformly emitting disk profile with a radius of 3° that moreover is offset from the cluster center. Here, we demonstrate that the significance of this extended emission strongly depends on the adopted interstellar emission model (IEM) and is most likely an artifact of our incomplete description of the IEM in this region. Furthermore, we also search for and find new point source candidates in the region. We then derive conservative upper limits on the velocity-averaged DM pair annihilation cross section from Virgo. We take into account the potential γ-ray flux enhancement due to DM sub-halos and its complex morphology as a merging cluster. For DM annihilating intomore » $$b\\bar{b},$$ assuming a conservative sub-halo model setup, we find limits that are between 1 and 1.5 orders of magnitude above the expectation from the thermal cross section for mDM lesssim 100 GeV. In a more optimistic scenario, we exclude $$\\langle \\sigma v\\rangle \\sim 3\\times {10}^{-26}\\;{\\mathrm{cm}}^{3}\\;{{\\rm{s}}}^{-1}$$ for m DM $$\\lesssim$$ 40 GeV for the same channel. Finally, we derive upper limits on the γ-ray-flux produced by hadronic cosmic-ray interactions in the inter cluster medium. We find that the volume-averaged cosmic-ray-to-thermal pressure ratio is less than ~6%.« less

  6. Computing the cross sections of nuclear reactions with nuclear clusters emission for proton energies between 30 MeV and 2.6 GeV

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Korovin, Yu. A.; Maksimushkina, A. V., E-mail: AVMaksimushkina@mephi.ru; Frolova, T. A.

    2016-12-15

    The cross sections of nuclear reactions involving emission of clusters of light nuclei in proton collisions with a heavy-metal target are computed for incident-proton energies between 30 MeV and 2.6 GeV. The calculation relies on the ALICE/ASH and CASCADE/INPE computer codes. The parameters determining the pre-equilibrium cluster emission are varied in the computation.

  7. HIV Transmission Networks in the San Diego-Tijuana Border Region.

    PubMed

    Mehta, Sanjay R; Wertheim, Joel O; Brouwer, Kimberly C; Wagner, Karla D; Chaillon, Antoine; Strathdee, Steffanie; Patterson, Thomas L; Rangel, Maria G; Vargas, Mlenka; Murrell, Ben; Garfein, Richard; Little, Susan J; Smith, Davey M

    2015-10-01

    HIV sequence data can be used to reconstruct local transmission networks. Along international borders, like the San Diego-Tijuana region, understanding the dynamics of HIV transmission across reported risks, racial/ethnic groups, and geography can help direct effective prevention efforts on both sides of the border. We gathered sociodemographic, geographic, clinical, and viral sequence data from HIV infected individuals participating in ten studies in the San Diego-Tijuana border region. Phylogenetic and network analysis was performed to infer putative relationships between HIV sequences. Correlates of identified clusters were evaluated and spatiotemporal relationships were explored using Bayesian phylogeographic analysis. After quality filtering, 843 HIV sequences with associated demographic data and 263 background sequences from the region were analyzed, and 138 clusters were inferred (2-23 individuals). Overall, the rate of clustering did not differ by ethnicity, residence, or sex, but bisexuals were less likely to cluster than heterosexuals or men who have sex with men (p = 0.043), and individuals identifying as white (p ≤ 0.01) were more likely to cluster than other races. Clustering individuals were also 3.5 years younger than non-clustering individuals (p < 0.001). Although the sampled San Diego and Tijuana epidemics were phylogenetically compartmentalized, five clusters contained individuals residing on both sides of the border. This study sampled ~ 7% of HIV infected individuals in the border region, and although the sampled networks on each side of the border were largely separate, there was evidence of persistent bidirectional cross-border transmissions that linked risk groups, thus highlighting the importance of the border region as a "melting pot" of risk groups. NIH, VA, and Pendleton Foundation.

  8. Deep UV Luminosity Functions at the Infall Region of the Coma Cluster

    NASA Technical Reports Server (NTRS)

    Hammer, D. M.; Hornschemeier, A. E.; Salim, S.; Smith, R.; Jenkins, L.; Mobasher, B.; Miller, N.; Ferguson, H.

    2011-01-01

    We have used deep GALEX observations at the infall region of the Coma cluster to measure the faintest UV luminosity functions (LFs) presented for a rich galaxy cluster thus far. The Coma UV LFs are measured to M(sub uv) = -10.5 in the GALEX FUV and NUV bands, or 3.5 mag fainter than previous studies, and reach the dwarf early-type galaxy population in Coma for the first time. The Schechter faint-end slopes (alpha approximately equal to -1.39 in both GALEX bands) are shallower than reported in previous Coma UV LF studies owing to a flatter LF at faint magnitudes. A Gaussian-plus-Schechter model provides a slightly better parametrization of the UV LFs resulting in a faint-end slope of alpha approximately equal to -1.15 in both GALEX bands. The two-component model gives faint-end slopes shallower than alpha = -1 (a turnover) for the LFs constructed separately for passive and star forming galaxies. The UV LFs for star forming galaxies show a turnover at M(sub UV) approximately equal to -14 owing to a deficit of dwarf star forming galaxies in Coma with stellar masses below M(sub *) = 10(sup 8) solar mass. A similar turnover is identified in recent UV LFs measured for the Virgo cluster suggesting this may be a common feature of local galaxy clusters, whereas the field UV LFs continue to rise at faint magnitudes. We did not identify an excess of passive galaxies as would be expected if the missing dwarf star forming galaxies were quenched inside the cluster. In fact, the LFs for both dwarf passive and star forming galaxies show the same turnover at faint magnitudes. We discuss the possible origin of the missing dwarf star forming galaxies in Coma and their expected properties based on comparisons to local field galaxies.

  9. Eastern region represents a worrying cluster of active hepatitis C in Algeria in 2012.

    PubMed

    Bensalem, Aïcha; Selmani, Karima; Hihi, Narjes; Bencherifa, Nesrine; Mostefaoui, Fatma; Kerioui, Cherif; Pineau, Pascal; Debzi, Nabil; Berkane, Saadi

    2016-08-01

    Algeria is the largest country of Africa, peopled with populations living a range of traditional/rural and modern/urban lifestyles. The variations of prevalence of chronic active hepatitis care poorly known on the Algerian territory. We conducted a retrospective survey on all patients (n = 998) referred to our institution in 2012 and confirmed by us for an active hepatitis C. Half of the hepatitis C virus (HCV) isolates were genotyped. Forty Algerian regions out of the 48 were represented in our study. Three geographical clusters (Aïn-Temouchent/SidiBelAbbes, Algiers, and a large Eastern region) with an excess of active hepatitis C were observed. Patients coming from the Eastern cluster (Batna, Khenchela, Oum el Bouaghi, and Tebessa) were strongly over-represented (49% of cases, OR = 14.5, P < 0.0001). The hallmarks of Eastern region were an excess of women (65% vs. 46% in the remaining population, P < 0.0001) and the almost exclusive presence of HCV genotype 1 (93% vs. 63%, P = 0.0001). The core of the epidemics was apparently located in Khenchela (odds ratio = 24.6, P < 0.0001). This situation is plausibly connected with nosocomial transmission or traditional practices as scarification (Hijama), piercing or tattooing, very lively in this region. Distinct hepatitis C epidemics are currently affecting Algerian population. The most worrying situation is observed in rural regions located east of Algeria. J. Med. Virol. 88:1394-1403, 2016. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  10. Semi-supervised clustering for parcellating brain regions based on resting state fMRI data

    NASA Astrophysics Data System (ADS)

    Cheng, Hewei; Fan, Yong

    2014-03-01

    Many unsupervised clustering techniques have been adopted for parcellating brain regions of interest into functionally homogeneous subregions based on resting state fMRI data. However, the unsupervised clustering techniques are not able to take advantage of exiting knowledge of the functional neuroanatomy readily available from studies of cytoarchitectonic parcellation or meta-analysis of the literature. In this study, we propose a semi-supervised clustering method for parcellating amygdala into functionally homogeneous subregions based on resting state fMRI data. Particularly, the semi-supervised clustering is implemented under the framework of graph partitioning, and adopts prior information and spatial consistent constraints to obtain a spatially contiguous parcellation result. The graph partitioning problem is solved using an efficient algorithm similar to the well-known weighted kernel k-means algorithm. Our method has been validated for parcellating amygdala into 3 subregions based on resting state fMRI data of 28 subjects. The experiment results have demonstrated that the proposed method is more robust than unsupervised clustering and able to parcellate amygdala into centromedial, laterobasal, and superficial parts with improved functionally homogeneity compared with the cytoarchitectonic parcellation result. The validity of the parcellation results is also supported by distinctive functional and structural connectivity patterns of the subregions and high consistency between coactivation patterns derived from a meta-analysis and functional connectivity patterns of corresponding subregions.

  11. Aura in Cluster Headache: A Cross-Sectional Study.

    PubMed

    de Coo, Ilse F; Wilbrink, Leopoldine A; Ie, Gaby D; Haan, Joost; Ferrari, Michel D

    2018-06-22

    Aura symptoms have been reported in up to 23% of cluster headache patients, but it is not known whether clinical characteristics are different in participants with and without aura. Using validated web-based questionnaires we assessed the presence and characteristics of attack-related aura and other clinical features in 629 subjects available for analysis from an initial cohort of 756 cluster headache subjects. Participants who screened positive for aura were contacted by telephone for confirmation of the ICHD-III criteria for aura. Typical aura symptoms before or during cluster headache attacks were found in 44/629 participants (7.0%) mainly involving visual symptoms (61.4%). Except for lower alcohol consumption and higher prevalence of frontal pain in participants with aura, no differences in clinical characteristics were found compared with participants without aura. At least 7.0% of the participants with cluster headache in our large cohort reported typical aura symptoms, which most often involved visual symptoms. No major clinical differences were found between participants with and without aura. © 2018 The Authors. Headache: The Journal of Head and Face Pain published by Wiley Periodicals, Inc. on behalf of American Headache Society.

  12. Two novel translocation breakpoints upstream of SOX9 define borders of the proximal and distal breakpoint cluster region in campomelic dysplasia.

    PubMed

    Leipoldt, M; Erdel, M; Bien-Willner, G A; Smyk, M; Theurl, M; Yatsenko, S A; Lupski, J R; Lane, A H; Shanske, A L; Stankiewicz, P; Scherer, G

    2007-01-01

    The semilethal skeletal malformation syndrome campomelic dysplasia (CD) with or without XY sex reversal is caused by mutations within the SOX9 gene on 17q24.3 or by chromosomal aberrations (translocations, inversions or deletions) with breakpoints outside the SOX9 coding region. The previously published CD translocation breakpoints upstream of SOX9 fall into two clusters: a proximal cluster with breakpoints between 50-300 kb and a distal cluster with breakpoints between 899-932 kb. Here, we present clinical, cytogenetic and molecular data from two novel CD translocation cases. Case 1 with karyotype 46,XY,t(1;17)(q42.1;q24.3) has characteristic symptoms of CD, including mild tibial bowing, cryptorchidism and hypospadias. By standard fluorescence in situ hybridization (FISH) and by high-resolution fiber FISH, the 17q breakpoint was mapped 375 kb from SOX9, defining the centromeric border of the proximal breakpoint cluster region. Case 2 with karyotype 46,X,t(Y;17)(q11.2;q24.3) has the acampomelic form of CD and complete XY sex reversal. By FISH and somatic cell hybrid analysis, the 17q breakpoint was mapped 789 kb from SOX9, defining the telomeric border of the distal breakpoint cluster region. We discuss the structure of the 1 Mb cis-control region upstream of SOX9 and the correlation between the position of the 14 mapped translocation breakpoints with respect to disease severity and XY sex reversal.

  13. WordCluster: detecting clusters of DNA words and genomic elements

    PubMed Central

    2011-01-01

    Background Many k-mers (or DNA words) and genomic elements are known to be spatially clustered in the genome. Well established examples are the genes, TFBSs, CpG dinucleotides, microRNA genes and ultra-conserved non-coding regions. Currently, no algorithm exists to find these clusters in a statistically comprehensible way. The detection of clustering often relies on densities and sliding-window approaches or arbitrarily chosen distance thresholds. Results We introduce here an algorithm to detect clusters of DNA words (k-mers), or any other genomic element, based on the distance between consecutive copies and an assigned statistical significance. We implemented the method into a web server connected to a MySQL backend, which also determines the co-localization with gene annotations. We demonstrate the usefulness of this approach by detecting the clusters of CAG/CTG (cytosine contexts that can be methylated in undifferentiated cells), showing that the degree of methylation vary drastically between inside and outside of the clusters. As another example, we used WordCluster to search for statistically significant clusters of olfactory receptor (OR) genes in the human genome. Conclusions WordCluster seems to predict biological meaningful clusters of DNA words (k-mers) and genomic entities. The implementation of the method into a web server is available at http://bioinfo2.ugr.es/wordCluster/wordCluster.php including additional features like the detection of co-localization with gene regions or the annotation enrichment tool for functional analysis of overlapped genes. PMID:21261981

  14. Variability among Cucurbitaceae species (melon, cucumber and watermelon) in a genomic region containing a cluster of NBS-LRR genes.

    PubMed

    Morata, Jordi; Puigdomènech, Pere

    2017-02-08

    Cucurbitaceae species contain a significantly lower number of genes coding for proteins with similarity to plant resistance genes belonging to the NBS-LRR family than other plant species of similar genome size. A large proportion of these genes are organized in clusters that appear to be hotspots of variability. The genomes of the Cucurbitaceae species measured until now are intermediate in size (between 350 and 450 Mb) and they apparently have not undergone any genome duplications beside those at the origin of eudicots. The cluster containing the largest number of NBS-LRR genes has previously been analyzed in melon and related species and showed a high degree of interspecific and intraspecific variability. It was of interest to study whether similar behavior occurred in other cluster of the same family of genes. The cluster of NBS-LRR genes located in melon chromosome 9 was analyzed and compared with the syntenic regions in other cucurbit genomes. This is the second cluster in number within this species and it contains nine sequences with a NBS-LRR annotation including two genes, Fom1 and Prv, providing resistance against Fusarium and Ppapaya ring-spot virus (PRSV). The variability within the melon species appears to consist essentially of single nucleotide polymorphisms. Clusters of similar genes are present in the syntenic regions of the two species of Cucurbitaceae that were sequenced, cucumber and watermelon. Most of the genes in the syntenic clusters can be aligned between species and a hypothesis of generation of the cluster is proposed. The number of genes in the watermelon cluster is similar to that in melon while a higher number of genes (12) is present in cucumber, a species with a smaller genome than melon. After comparing genome resequencing data of 115 cucumber varieties, deletion of a group of genes is observed in a group of varieties of Indian origin. Clusters of genes coding for NBS-LRR proteins in cucurbits appear to have specific variability in

  15. Developing a regional ITS architecture : a cross-cutting study : building a framework for regional ITS integration

    DOT National Transportation Integrated Search

    1999-09-01

    This report highlights cross-cutting findings and perspectives gleaned from a series of case studies that examined the development processes of regional and statewide Intelligent Transportation Systems (ITS) architectures. Each of the case studies is...

  16. Spatial clustering of high load ocular Chlamydia trachomatis infection in trachoma: a cross-sectional population-based study.

    PubMed

    Last, Anna; Burr, Sarah; Alexander, Neal; Harding-Esch, Emma; Roberts, Chrissy H; Nabicassa, Meno; Cassama, Eunice Teixeira da Silva; Mabey, David; Holland, Martin; Bailey, Robin

    2017-07-31

    Chlamydia trachomatis (Ct) is the most common cause of bacterial sexually transmitted infection and infectious cause of blindness (trachoma) worldwide. Understanding the spatial distribution of Ct infection may enable us to identify populations at risk and improve our understanding of Ct transmission. In this study, we sought to investigate the spatial distribution of Ct infection and the clinical features associated with high Ct load in trachoma-endemic communities on the Bijagós Archipelago (Guinea Bissau). We collected 1507 conjunctival samples and corresponding detailed clinical data during a cross-sectional population-based geospatially representative trachoma survey. We used droplet digital PCR to estimate Ct load on conjunctival swabs. Geostatistical tools were used to investigate clustering of ocular Ct infections. Spatial clusters (independent of age and gender) of individuals with high Ct loads were identified using local indicators of spatial association. We did not detect clustering of individuals with low load infections. These data suggest that infections with high bacterial load may be important in Ct transmission. These geospatial tools may be useful in the study of ocular Ct transmission dynamics and as part of trachoma surveillance post-treatment, to identify clusters of infection and thresholds of Ct load that may be important foci of re-emergent infection in communities. © FEMS 2017.

  17. Wavelet-based clustering of resting state MRI data in the rat.

    PubMed

    Medda, Alessio; Hoffmann, Lukas; Magnuson, Matthew; Thompson, Garth; Pan, Wen-Ju; Keilholz, Shella

    2016-01-01

    While functional connectivity has typically been calculated over the entire length of the scan (5-10min), interest has been growing in dynamic analysis methods that can detect changes in connectivity on the order of cognitive processes (seconds). Previous work with sliding window correlation has shown that changes in functional connectivity can be observed on these time scales in the awake human and in anesthetized animals. This exciting advance creates a need for improved approaches to characterize dynamic functional networks in the brain. Previous studies were performed using sliding window analysis on regions of interest defined based on anatomy or obtained from traditional steady-state analysis methods. The parcellation of the brain may therefore be suboptimal, and the characteristics of the time-varying connectivity between regions are dependent upon the length of the sliding window chosen. This manuscript describes an algorithm based on wavelet decomposition that allows data-driven clustering of voxels into functional regions based on temporal and spectral properties. Previous work has shown that different networks have characteristic frequency fingerprints, and the use of wavelets ensures that both the frequency and the timing of the BOLD fluctuations are considered during the clustering process. The method was applied to resting state data acquired from anesthetized rats, and the resulting clusters agreed well with known anatomical areas. Clusters were highly reproducible across subjects. Wavelet cross-correlation values between clusters from a single scan were significantly higher than the values from randomly matched clusters that shared no temporal information, indicating that wavelet-based analysis is sensitive to the relationship between areas. Copyright © 2015 Elsevier Inc. All rights reserved.

  18. CLustre: semi-automated lineament clustering for palaeo-glacial reconstruction

    NASA Astrophysics Data System (ADS)

    Smith, Mike; Anders, Niels; Keesstra, Saskia

    2016-04-01

    Palaeo glacial reconstructions, or "inversions", using evidence from the palimpsest landscape are increasingly being undertaken with larger and larger databases. Predominant in landform evidence is the lineament (or drumlin) where the biggest datasets number in excess of 50,000 individual forms. One stage in the inversion process requires the identification of lineaments that are generically similar and then their subsequent interpretation in to a coherent chronology of events. Here we present CLustre, a semi-authomated algorithm that clusters lineaments using a locally adaptive, region growing, method. This is initially tested using 1,500 model runs on a synthetic dataset, before application to two case studies (where manual clustering has been undertaken by independent researchers): (1) Dubawnt Lake, Canada and (2) Victoria island, Canada. Results using the synthetic data show that classifications are robust in most scenarios, although specific cases of cross-cutting lineaments may lead to incorrect clusters. Application to the case studies showed a very good match to existing published work, with differences related to limited numbers of unclassified lineaments and parallel cross-cutting lineaments. The value in CLustre comes from the semi-automated, objective, application of a classification method that is repeatable. Once classified, summary statistics of lineament groups can be calculated and then used in the inversion.

  19. Proper motions and membership probabilities of stars in the region of globular cluster NGC 6366

    NASA Astrophysics Data System (ADS)

    Sariya, Devesh P.; Yadav, R. K. S.

    2015-12-01

    Context. NGC 6366 is a metal-rich globular cluster that is relatively unstudied. It is a kinematically interesting cluster, reported as belonging to the slowly rotating halo system, which is unusual given its metallicity and spatial location in the Galaxy. Aims: The purpose of this research is to determine the relative proper motion and membership probability of the stars in the region of globular cluster NGC 6366. To target cluster members reliably during spectroscopic surveys without including field stars, a good proper motion and membership probability catalogue of NGC 6366 is needed. Methods: To derive relative proper motions, the archival data from the Wide Field Imager mounted on the ESO 2.2 m telescope have been reduced using a high precision astrometric software. The images used are in the B,V, and I photometric bands with an epoch gap of ~3.2 yr. The calibrated BVI magnitudes have been determined using recent data for secondary standard stars. Results: We determined relative proper motions and cluster membership probabilities for 2530 stars in the field of globular cluster NGC 6366. The median proper motion rms errors for stars brighter than V ~ 18 mag is ~2 mas yr-1, which gradually increases to ~5 mas yr-1 for stars having magnitudes V ~ 20 mag. Based on the membership catalogue, we checked the membership status of the X-ray sources and variable stars of NGC 6366 mentioned in the literature. We also provide the astronomical community with an electronic catalogue that includes B, V, and I magnitudes; relative proper motions; and membership probabilities of the stars in the region of NGC 6366. Based on observations with the MPG/ESO 2.2 m and ESO/VLT telescopes, located at La Silla and Paranal Observatory, Chile, under DDT programs 164.O-0561(F), 71.D-0220(A) and the archive material.Full Table 4 is only available at the CDS via anonymous ftp to http://cdsarc.u-strasbg.fr (ftp://130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/584/A59

  20. HIV Transmission Networks in the San Diego–Tijuana Border Region

    PubMed Central

    Mehta, Sanjay R.; Wertheim, Joel O.; Brouwer, Kimberly C.; Wagner, Karla D.; Chaillon, Antoine; Strathdee, Steffanie; Patterson, Thomas L.; Rangel, Maria G.; Vargas, Mlenka; Murrell, Ben; Garfein, Richard; Little, Susan J.; Smith, Davey M.

    2015-01-01

    Background HIV sequence data can be used to reconstruct local transmission networks. Along international borders, like the San Diego–Tijuana region, understanding the dynamics of HIV transmission across reported risks, racial/ethnic groups, and geography can help direct effective prevention efforts on both sides of the border. Methods We gathered sociodemographic, geographic, clinical, and viral sequence data from HIV infected individuals participating in ten studies in the San Diego–Tijuana border region. Phylogenetic and network analysis was performed to infer putative relationships between HIV sequences. Correlates of identified clusters were evaluated and spatiotemporal relationships were explored using Bayesian phylogeographic analysis. Findings After quality filtering, 843 HIV sequences with associated demographic data and 263 background sequences from the region were analyzed, and 138 clusters were inferred (2–23 individuals). Overall, the rate of clustering did not differ by ethnicity, residence, or sex, but bisexuals were less likely to cluster than heterosexuals or men who have sex with men (p = 0.043), and individuals identifying as white (p ≤ 0.01) were more likely to cluster than other races. Clustering individuals were also 3.5 years younger than non-clustering individuals (p < 0.001). Although the sampled San Diego and Tijuana epidemics were phylogenetically compartmentalized, five clusters contained individuals residing on both sides of the border. Interpretation This study sampled ~ 7% of HIV infected individuals in the border region, and although the sampled networks on each side of the border were largely separate, there was evidence of persistent bidirectional cross-border transmissions that linked risk groups, thus highlighting the importance of the border region as a “melting pot” of risk groups. Funding NIH, VA, and Pendleton Foundation. PMID:26629540

  1. Testing the Large-scale Environments of Cool-core and Non-cool-core Clusters with Clustering Bias

    NASA Astrophysics Data System (ADS)

    Medezinski, Elinor; Battaglia, Nicholas; Coupon, Jean; Cen, Renyue; Gaspari, Massimo; Strauss, Michael A.; Spergel, David N.

    2017-02-01

    There are well-observed differences between cool-core (CC) and non-cool-core (NCC) clusters, but the origin of this distinction is still largely unknown. Competing theories can be divided into internal (inside-out), in which internal physical processes transform or maintain the NCC phase, and external (outside-in), in which the cluster type is determined by its initial conditions, which in turn leads to different formation histories (I.e., assembly bias). We propose a new method that uses the relative assembly bias of CC to NCC clusters, as determined via the two-point cluster-galaxy cross-correlation function (CCF), to test whether formation history plays a role in determining their nature. We apply our method to 48 ACCEPT clusters, which have well resolved central entropies, and cross-correlate with the SDSS-III/BOSS LOWZ galaxy catalog. We find that the relative bias of NCC over CC clusters is b = 1.42 ± 0.35 (1.6σ different from unity). Our measurement is limited by the small number of clusters with core entropy information within the BOSS footprint, 14 CC and 34 NCC clusters. Future compilations of X-ray cluster samples, combined with deep all-sky redshift surveys, will be able to better constrain the relative assembly bias of CC and NCC clusters and determine the origin of the bimodality.

  2. Testing the Large-scale Environments of Cool-core and Non-cool-core Clusters with Clustering Bias

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Medezinski, Elinor; Battaglia, Nicholas; Cen, Renyue

    2017-02-10

    There are well-observed differences between cool-core (CC) and non-cool-core (NCC) clusters, but the origin of this distinction is still largely unknown. Competing theories can be divided into internal (inside-out), in which internal physical processes transform or maintain the NCC phase, and external (outside-in), in which the cluster type is determined by its initial conditions, which in turn leads to different formation histories (i.e., assembly bias). We propose a new method that uses the relative assembly bias of CC to NCC clusters, as determined via the two-point cluster-galaxy cross-correlation function (CCF), to test whether formation history plays a role in determiningmore » their nature. We apply our method to 48 ACCEPT clusters, which have well resolved central entropies, and cross-correlate with the SDSS-III/BOSS LOWZ galaxy catalog. We find that the relative bias of NCC over CC clusters is b = 1.42 ± 0.35 (1.6 σ different from unity). Our measurement is limited by the small number of clusters with core entropy information within the BOSS footprint, 14 CC and 34 NCC clusters. Future compilations of X-ray cluster samples, combined with deep all-sky redshift surveys, will be able to better constrain the relative assembly bias of CC and NCC clusters and determine the origin of the bimodality.« less

  3. Health region development from the perspective of system theory - an empirical cross-regional case study.

    PubMed

    Volgger, Michael; Mainil, Tomas; Pechlaner, Harald; Mitas, Ondrej

    2015-01-01

    Governments are increasingly establishing health regions to deal with current challenges of public health service. These regions are seen as instruments to balance public and private stakeholders, and offer health care to regional citizens as well as to medical/health tourists. However, it is still unclear how the development of such health regions as well as their governance may be conceptualized. We apply Luhmann's system theory approach in the context of a cross-regional case study that compares health region developments in the Autonomous Province of Bolzano-South Tyrol (Italy) with particular regard to the Eastern Dolomites and in the province of Zeeland (the Netherlands). We suggest that Luhmann's system theory provides a useful set of criteria to evaluate and judge health region development. Fully developed health regions can be understood as auto-poietic systems. By emphasizing programs, personnel, and communication channels, these case studies illustrate the suitability of the system theory toolset to analyze the governance and spatial embeddedness of health regions. Additionally, the study contributes to literature by indicating that health regions are closely related to identity issues and to decision making in regions. Copyright © 2014 Elsevier Ltd. All rights reserved.

  4. Cluster: Mission Overview and End-of-Life Analysis

    NASA Technical Reports Server (NTRS)

    Pallaschke, S.; Munoz, I.; Rodriquez-Canabal, J.; Sieg, D.; Yde, J. J.

    2007-01-01

    The Cluster mission is part of the scientific programme of the European Space Agency (ESA) and its purpose is the analysis of the Earth's magnetosphere. The Cluster project consists of four satellites. The selected polar orbit has a shape of 4.0 and 19.2 Re which is required for performing measurements near the cusp and the tail of the magnetosphere. When crossing these regions the satellites form a constellation which in most of the cases so far has been a regular tetrahedron. The satellite operations are carried out by the European Space Operations Centre (ESOC) at Darmstadt, Germany. The paper outlines the future orbit evolution and the envisaged operations from a Flight Dynamics point of view. In addition a brief summary of the LEOP and routine operations is included beforehand.

  5. Mapping New Mobility business, innovation, and employment opportunities in Michigan : developing a data-driven graphical platform for assessing and advancing industry cluster development and entrepreneurship opportunities in urban regions : USDOT Region V

    DOT National Transportation Integrated Search

    2016-12-15

    Across regional economic development leaders and policy makers, the concept of clustering has grown in importance as a framework for structuring economic growth and resurgence (Muro & Katz, 2010). Cluster identification is most often treated as a com...

  6. DEEP ULTRAVIOLET LUMINOSITY FUNCTIONS AT THE INFALL REGION OF THE COMA CLUSTER

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hammer, D. M.; Hornschemeier, A. E.; Jenkins, L.

    2012-02-01

    We have used deep GALEX observations at the infall region of the Coma cluster to measure the faintest ultraviolet (UV) luminosity functions (LFs) presented for a rich galaxy cluster thus far. The Coma UV LFs are measured to M{sub UV} = -10.5 in the GALEX FUV and NUV bands, or 3.5 mag fainter than previous studies, and reach the dwarf early-type galaxy population in Coma for the first time. The Schechter faint-end slopes ({alpha} Almost-Equal-To -1.39 in both GALEX bands) are shallower than reported in previous Coma UV LF studies owing to a flatter LF at faint magnitudes. A Gaussian-plus-Schechtermore » model provides a slightly better parameterization of the UV LFs resulting in a faint-end slope of {alpha} Almost-Equal-To -1.15 in both GALEX bands. The two-component model gives faint-end slopes shallower than {alpha} = -1 (a turnover) for the LFs constructed separately for passive and star-forming galaxies. The UV LFs for star-forming galaxies show a turnover at M{sub UV} Almost-Equal-To -14 owing to a deficit of dwarf star-forming galaxies in Coma with stellar masses below M{sub *} = 10{sup 8} M{sub Sun }. A similar turnover is identified in recent UV LFs measured for the Virgo cluster suggesting this may be a common feature of local galaxy clusters, whereas the field UV LFs continue to rise at faint magnitudes. We did not identify an excess of passive galaxies as would be expected if the missing dwarf star-forming galaxies were quenched inside the cluster. In fact, the LFs for both dwarf passive and star-forming galaxies show the same turnover at faint magnitudes. We discuss the possible origin of the missing dwarf star-forming galaxies in Coma and their expected properties based on comparisons to local field galaxies.« less

  7. [Medicen Paris Région: A world-class ''competitiveness cluster'' in the Paris region incorporating a neuroscience ''subcluster''].

    PubMed

    Canet, Emmanuel

    2007-04-01

    The French public-private partnerships known as "competitive clusters" [pôles de compétitivité (PdC)] are intended to be novel and ambitious engines of regional growth, employment and biomedical innovation. Partly funded by government and local councils, they aim to capitalize on regional expertise by bringing together basic scientists, clinicians, innovative entrepreneurs and local decision-makers around specific themes that have become too costly and complex for any of these actors to tackle alone. Clusters provide the critical mass required both to underpin innovation potential and to authenticate regional claims to international competitiveness. Medicen is a biomedicine and therapeutics cluster comprising 120 partners from four broad "colleges" in the greater Paris region: major industry, small and medium-sized businesses, teaching hospitals/State research bodies, and local councils. Chief among its cooperative R&D projects is the neuroscience subcluster, in which "TransAl" the neurodegenerative disease project, counts Sanofi-Aventis, Servier and the French Atomic Energy Commission [Commissariat à l'Energie Atomique (CEA)] as key partners. One main aim is to develop an experimental model in rhesus monkeys in which a putative cause of Alzheimer's disease, intracerebral accumulation of b-amyloid peptide, is generated by impairing the peptide's clearance. The other aim, in which the nuclear medicine expertise of the CEA will be crucial, is to identify, characterize and validate markers for magnetic resonance and positron emission tomography imaging, and to source biomarkers from cerebrospinal fluid proteomics. A human biological resource centre (DNA and tissue banks) project dedicated to neurological and psychiatric disease should be up and running in 2007. Only through fundamental restructuring of resources on such a large cooperative scale are solutions likely to be found to the major problems of modern medicine, bringing healthcare and regional

  8. Spatial clustering and halo occupation distribution modelling of local AGN via cross-correlation measurements with 2MASS galaxies

    NASA Astrophysics Data System (ADS)

    Krumpe, Mirko; Miyaji, Takamitsu; Coil, Alison L.; Aceves, Hector

    2018-02-01

    We present the clustering properties and halo occupation distribution (HOD) modelling of very low redshift, hard X-ray-detected active galactic nuclei (AGN) using cross-correlation function measurements with Two-Micron All Sky Survey galaxies. Spanning a redshift range of 0.007 < z < 0.037, with a median z = 0.024, we present a precise AGN clustering study of the most local AGN in the Universe. The AGN sample is drawn from the SWIFT/BAT 70-month and INTEGRAL/IBIS eight year all-sky X-ray surveys and contains both type I and type II AGN. We find a large-scale bias for the full AGN sample of b=1.04^{+0.10}_{-0.11}, which corresponds to a typical host dark matter halo mass of M_h^typ=12.84^{+0.22}_{-0.30} h^{-1} M_{⊙}. When split into low and high X-ray luminosity and type I and type II AGN subsamples, we detect no statistically significant differences in the large-scale bias parameters. However, there are differences in the small-scale clustering, which are reflected in the full HOD model results. We find that low and high X-ray luminosity AGN, as well as type I and type II AGN, occupy dark matter haloes differently, with 3.4σ and 4.0σ differences in their mean halo masses, respectively, when split by luminosity and type. The latter finding contradicts a simple orientation-based AGN unification model. As a by-product of our cross-correlation approach, we also present the first HOD model of 2MASS galaxies.

  9. Interpretive geologic cross sections for the Death Valley regional flow system and surrounding areas, Nevada and California

    USGS Publications Warehouse

    Sweetkind, D.S.; Dickerson, R.P.; Blakely, R.J.; Denning, Paul

    2001-01-01

    This report presents a network of 28 geologic cross sections that portray subsurface geologic relations within the Death Valley regional ground-water system, a ground-water basin that encompasses a 3? x 3? area (approximately 70,000 km2) in southern Nevada and eastern California. The cross sections transect that part of the southern Great Basin that includes Death Valley, the Nevada Test Site, and the potential high-level nuclear waste underground repository at Yucca Mountain. The specific geometric relationships portrayed on the cross sections are discussed in the context of four general sub-regions that have stratigraphic similarities and general consistency of structural style: (1) the Nevada Test Site vicinity; (2) the Spring Mountains, Pahrump Valley and Amargosa Desert region; (3) the Death Valley region; and (4) the area east of the Nevada Test Site. The subsurface geologic interpretations portrayed on the cross sections are based on an integration of existing geologic maps, measured stratigraphic sections, published cross sections, well data, and geophysical data and interpretations. The estimated top of pre-Cenozoic rocks in the cross sections is based on inversion of gravity data, but the deeper parts of the sections are based on geologic conceptual models and are more speculative. The region transected by the cross sections includes part of the southern Basin and Range Province, the northwest-trending Walker Lane belt, the Death Valley region, and the northern Mojave Desert. The region is structurally complex, where a locally thick Tertiary volcanic and sedimentary section unconformably overlies previously deformed Proterozoic through Paleozoic rocks. All of these rocks have been deformed by complex Neogene ex-tensional normal and strike-slip faults. These cross sections form a three-dimensional network that portrays the interpreted stratigraphic and structural relations in the region; the sections form part of the geologic framework that will be

  10. Seismic Hazard and risk assessment for Romania -Bulgaria cross-border region

    NASA Astrophysics Data System (ADS)

    Simeonova, Stela; Solakov, Dimcho; Alexandrova, Irena; Vaseva, Elena; Trifonova, Petya; Raykova, Plamena

    2016-04-01

    Among the many kinds of natural and man-made disasters, earthquakes dominate with regard to their social and economical impact on the urban environment. Global seismic hazard and vulnerability to earthquakes are steadily increasing as urbanization and development occupy more areas that are prone to effects of strong earthquakes. The assessment of the seismic hazard and risk is particularly important, because it provides valuable information for seismic safety and disaster mitigation, and it supports decision making for the benefit of society. Romania and Bulgaria, situated in the Balkan Region as a part of the Alpine-Himalayan seismic belt, are characterized by high seismicity, and are exposed to a high seismic risk. Over the centuries, both countries have experienced strong earthquakes. The cross-border region encompassing the northern Bulgaria and southern Romania is a territory prone to effects of strong earthquakes. The area is significantly affected by earthquakes occurred in both countries, on the one hand the events generated by the Vrancea intermediate-depth seismic source in Romania, and on the other hand by the crustal seismicity originated in the seismic sources: Shabla (SHB), Dulovo, Gorna Orjahovitza (GO) in Bulgaria. The Vrancea seismogenic zone of Romania is a very peculiar seismic source, often described as unique in the world, and it represents a major concern for most of the northern part of Bulgaria as well. In the present study the seismic hazard for Romania-Bulgaria cross-border region on the basis of integrated basic geo-datasets is assessed. The hazard results are obtained by applying two alternative approaches - probabilistic and deterministic. The MSK64 intensity (MSK64 scale is practically equal to the new EMS98) is used as output parameter for the hazard maps. We prefer to use here the macroseismic intensity instead of PGA, because it is directly related to the degree of damages and, moreover, the epicentral intensity is the original

  11. On-the-fly Doppler broadening of unresolved resonance region cross sections

    DOE PAGES

    Walsh, Jonathan A.; Forget, Benoit; Smith, Kord S.; ...

    2017-07-29

    In this paper, two methods for computing temperature-dependent unresolved resonance region cross sections on-the-fly within continuous-energy Monte Carlo neutron transport simulations are presented. The first method calculates Doppler broadened cross sections directly from zero-temperature average resonance parameters. In a simulation, at each event that requires cross section values, a realization of unresolved resonance parameters is generated about the desired energy and temperature-dependent single-level Breit-Wigner resonance cross sections are computed directly via the analytical Ψ-x Doppler integrals. The second method relies on the generation of equiprobable cross section magnitude bands on an energy-temperature mesh. Within a simulation, the bands are sampledmore » and interpolated in energy and temperature to obtain cross section values on-the-fly. Both of the methods, as well as their underlying calculation procedures, are verified numerically in extensive code-to-code comparisons. Energy-dependent pointwise cross sections calculated with the newly-implemented procedures are shown to be in excellent agreement with those calculated by a widely-used nuclear data processing code. Relative differences at or below 0.1% are observed. Integral criticality benchmark results computed with the proposed methods are shown to reproduce those computed with a state-of-the-art processed nuclear data library very well. In simulations of fast spectrum systems which are highly-sensitive to the representation of cross section data in the unresolved region, k-eigenvalue and neutron flux spectra differences of <10 pcm and <1.0% are observed, respectively. The direct method is demonstrated to be well-suited to the calculation of reference solutions — against which results obtained with a discretized representation may be assessed — as a result of its treatment of the energy, temperature, and cross section magnitude variables as continuous. Also, because there is no pre

  12. Study of BenW (n = 1-12) clusters: An electron collision perspective

    NASA Astrophysics Data System (ADS)

    Modak, Paresh; Kaur, Jaspreet; Antony, Bobby

    2017-08-01

    This article explores electron scattering cross sections by Beryllium-Tungsten clusters (BenW). Beryllium and tungsten are important elements for plasma facing wall components, especially for the deuterium/tritium phase of ITER and in the recently installed JET. The present study focuses on different electron impact interactions in terms of elastic cross section (Qel), inelastic cross section (Qinel), ionization cross section (Qion), and momentum transfer cross section (Qmtcs) for the first twelve clusters belonging to the BenW family. It also predicts the evolution of the cross section with the size of the cluster. These cross sections are used as an input to model processes in plasma. The ionization cross section presented here is compared with the available reported data. This is the first comprehensive report on cross section data for all the above-mentioned scattering channels, to the best of our knowledge. Such broad analysis of cross section data gives vital insight into the study of local chemistry of electron interactions with BenW (n = 1-12) clusters in plasma.

  13. Hydrogen bonding interaction of small acetaldehyde clusters studied with core-electron excitation spectroscopy in the oxygen K-edge region

    NASA Astrophysics Data System (ADS)

    Tabayashi, K.; Chohda, M.; Yamanaka, T.; Tsutsumi, Y.; Takahashi, O.; Yoshida, H.; Taniguchi, M.

    2010-06-01

    In order to examine inner-shell electron excitation spectra of molecular clusters with strong multipole interactions, excitation spectra and time-of-flight (TOF) fragment-mass spectra of small acetaldehyde (AA) clusters have been studied under the beam conditions. The TOF spectra at the oxygen K-edge region showed an intense growth of the protonated clusters, MnH+ (M=CH3CHO) in the cluster beams. "cluster-specific" excitation spectra could be generated by monitoring partial-ion-yields of the protonated clusters. The most intense band of O1s→π*CO was found to shift to a higher energy by 0.15 eV relative to the monomer band upon clusterization. X-ray absorption spectra (XAS) were also calculated for the representative dimer configurations using a computer modelling program based on the density functional theory. The XAS prediction for the most stable (non-planar) configuration was found to give a close comparison with the cluster-band shift observed. The band shift was interpreted as being due to the HOMO-LUMO interaction within the complex where a contribution of vibrationally blue-shifting hydrogen bonding could be identified.

  14. Giant H II Regions in the Merging System NGC 3256: Are They the Birthplaces of Globular Clusters?

    NASA Astrophysics Data System (ADS)

    English, J.; Freeman, K. C.

    2003-03-01

    CCD images and spectra of ionized hydrogen in the merging system NGC 3256 were acquired as part of a kinematic study to investigate the formation of globular clusters (GCs) during the interactions and mergers of disk galaxies. This paper focuses on the proposition by Kennicutt & Chu that giant H II regions (GHRs), with an Hα luminosity greater than 1.5×1040 ergs s-1, are birthplaces of young populous clusters (YPCs). Although, compared with some other interacting systems, NGC 3256 has relatively few (seven) giant H II complexes, these regions are comparable in total flux to about 85 30 Doradus-like giant H II regions (GHRs). The bluest, massive YPCs (Zepf et al.) are located in the vicinity of observed 30 Dor GHRs, contributing to the notion that some fraction of 30 Dor GHRs do cradle massive YPCs, as 30 Dor harbors R136. If interactions induce the formation of 30 Dor GHRs, the observed luminosities indicate that almost 900 30 Dor GHRs would form in NGC 3256 throughout its merger epoch. In order for 30 Dor GHRs to be considered GC progenitors, this number must be consistent with the specific frequencies of globular clusters estimated for elliptical galaxies formed via mergers of spirals (Ashman & Zepf). This only requires that about 10% of NGC 3256's 900 30 Dor GHRs harbor YPCs, which survive several gigayears and have masses >=MR136.

  15. Constraining galaxy cluster velocity field with the thermal Sunyaev-Zel'dovich and kinematic Sunyaev-Zel'dovich cross-bispectrum

    NASA Astrophysics Data System (ADS)

    Hurier, G.

    2017-08-01

    The Sunyaev-Zel'dovich (SZ) effects are produced by the interaction of cosmic microwave background (CMB) photons with the ionized and diffuse gas of electrons inside galaxy clusters integrated along the line of sight. The two main effects are the thermal SZ (tSZ) produced by thermal pressure inside galaxy clusters and the kinematic SZ (kSZ) produced by peculiar motion of galaxy clusters compared to CMB rest-frame. The kSZ effect is particularly challenging to measure as it follows the same spectral behavior as the CMB, and consequently cannot be separated from the CMB using spectral considerations. In this paper, we explore the feasibility of detecting the kSZ through the computation of the tSZ-CMB-CMB cross-correlation bispectrum for current and future CMB experiments. We conclude that the next generation of CMB experiments will offer the possibility to detect the tSZ-kSZ-kSZ bispectrum at high signal-to-noise ration (S/N). This measurement will constraints the intra-cluster dynamics and the velocity field of galaxy cluster that is extremely sensitive to the growth rate of structures and thus to dark energy properties. Additionally, we also demonstrate that the tSZ-kSZ-kSZ bispectrum can be used to break the degeneracies between the mass-observable relation and the cosmological parameters to set tight constraints, up to 4%, on the Y - M relation calibration.

  16. Using DOUBLE STAR and CLUSTER Synoptic Observations to Test Global MHD Simulations of the Large-scale Topology of the Dayside Merging Region

    NASA Astrophysics Data System (ADS)

    Berchem, J.; Marchaudon, A.; Bosqued, J.; Escoubet, C. P.; Dunlop, M.; Owen, C. J.; Reme, H.; Balogh, A.; Carr, C.; Fazakerley, A. N.; Cao, J. B.

    2005-12-01

    Synoptic measurements from the DOUBLE STAR and CLUSTER spacecraft offer a unique opportunity to evaluate global models in simulating the complex topology and dynamics of the dayside merging region. We compare observations from the DOUBLE STAR TC-1 and CLUSTER spacecraft on May 8, 2004 with the predictions from a three-dimensional magnetohydrodynamic (MHD) simulation that uses plasma and magnetic field parameters measured upstream of the bow shock by the WIND spacecraft. Results from the global simulation are consistent with the large-scale features observed by CLUSTER and TC-1. We discuss topological changes and plasma flows at the dayside magnetospheric boundary inferred from the simulation results. The simulation shows that the DOUBLE STAR spacecraft passed through the dawn side merging region as the IMF rotated. In particular, the simulation indicates that at times TC-1 was very close to the merging region. In addition, we found that the bifurcation of the merging region in the simulation results is consistent with predictions by the antiparallel merging model. However, because of the draping of the magnetosheath field lines over the magnetopause, the positions and shape of the merging region differ significantly from those predicted by the model.

  17. Winter Precipitation Forecast in the European and Mediterranean Regions Using Cluster Analysis

    NASA Astrophysics Data System (ADS)

    Totz, Sonja; Tziperman, Eli; Coumou, Dim; Pfeiffer, Karl; Cohen, Judah

    2017-12-01

    The European climate is changing under global warming, and especially the Mediterranean region has been identified as a hot spot for climate change with climate models projecting a reduction in winter rainfall and a very pronounced increase in summertime heat waves. These trends are already detectable over the historic period. Hence, it is beneficial to forecast seasonal droughts well in advance so that water managers and stakeholders can prepare to mitigate deleterious impacts. We developed a new cluster-based empirical forecast method to predict precipitation anomalies in winter. This algorithm considers not only the strength but also the pattern of the precursors. We compare our algorithm with dynamic forecast models and a canonical correlation analysis-based prediction method demonstrating that our prediction method performs better in terms of time and pattern correlation in the Mediterranean and European regions.

  18. Network-based spatial clustering technique for exploring features in regional industry

    NASA Astrophysics Data System (ADS)

    Chou, Tien-Yin; Huang, Pi-Hui; Yang, Lung-Shih; Lin, Wen-Tzu

    2008-10-01

    In the past researches, industrial cluster mainly focused on single or particular industry and less on spatial industrial structure and mutual relations. Industrial cluster could generate three kinds of spillover effects, including knowledge, labor market pooling, and input sharing. In addition, industrial cluster indeed benefits industry development. To fully control the status and characteristics of district industrial cluster can facilitate to improve the competitive ascendancy of district industry. The related researches on industrial spatial cluster were of great significance for setting up industrial policies and promoting district economic development. In this study, an improved model, GeoSOM, that combines DBSCAN (Density-Based Spatial Clustering of Applications with Noise) and SOM (Self-Organizing Map) was developed for analyzing industrial cluster. Different from former distance-based algorithm for industrial cluster, the proposed GeoSOM model can calculate spatial characteristics between firms based on DBSCAN algorithm and evaluate the similarity between firms based on SOM clustering analysis. The demonstrative data sets, the manufacturers around Taichung County in Taiwan, were analyzed for verifying the practicability of the proposed model. The analyzed results indicate that GeoSOM is suitable for evaluating spatial industrial cluster.

  19. Infant immunization coverage in Italy: estimates by simultaneous EPI cluster surveys of regions. ICONA Study Group.

    PubMed Central

    Salmaso, S.; Rota, M. C.; Ciofi Degli Atti, M. L.; Tozzi, A. E.; Kreidl, P.

    1999-01-01

    In 1998, a series of regional cluster surveys (the ICONA Study) was conducted simultaneously in 19 out of the 20 regions in Italy to estimate the mandatory immunization coverage of children aged 12-24 months with oral poliovirus (OPV), diphtheria-tetanus (DT) and viral hepatitis B (HBV) vaccines, as well as optional immunization coverage with pertussis, measles and Haemophilus influenzae b (Hib) vaccines. The study children were born in 1996 and selected from birth registries using the Expanded Programme of Immunization (EPI) cluster sampling technique. Interviews with parents were conducted to determine each child's immunization status and the reasons for any missed or delayed vaccinations. The study population comprised 4310 children aged 12-24 months. Coverage for both mandatory and optional vaccinations differed by region. The overall coverage for mandatory vaccines (OPV, DT and HBV) exceeded 94%, but only 79% had been vaccinated in accord with the recommended schedule (i.e. during the first year of life). Immunization coverage for pertussis increased from 40% (1993 survey) to 88%, but measles coverage (56%) remained inadequate for controlling the disease; Hib coverage was 20%. These results confirm that in Italy the coverage of only mandatory immunizations is satisfactory. Pertussis immunization coverage has improved dramatically since the introduction of acellular vaccines. A greater effort to educate parents and physicians is still needed to improve the coverage of optional vaccinations in all regions. PMID:10593033

  20. Infant immunization coverage in Italy: estimates by simultaneous EPI cluster surveys of regions. ICONA Study Group.

    PubMed

    Salmaso, S; Rota, M C; Ciofi Degli Atti, M L; Tozzi, A E; Kreidl, P

    1999-01-01

    In 1998, a series of regional cluster surveys (the ICONA Study) was conducted simultaneously in 19 out of the 20 regions in Italy to estimate the mandatory immunization coverage of children aged 12-24 months with oral poliovirus (OPV), diphtheria-tetanus (DT) and viral hepatitis B (HBV) vaccines, as well as optional immunization coverage with pertussis, measles and Haemophilus influenzae b (Hib) vaccines. The study children were born in 1996 and selected from birth registries using the Expanded Programme of Immunization (EPI) cluster sampling technique. Interviews with parents were conducted to determine each child's immunization status and the reasons for any missed or delayed vaccinations. The study population comprised 4310 children aged 12-24 months. Coverage for both mandatory and optional vaccinations differed by region. The overall coverage for mandatory vaccines (OPV, DT and HBV) exceeded 94%, but only 79% had been vaccinated in accord with the recommended schedule (i.e. during the first year of life). Immunization coverage for pertussis increased from 40% (1993 survey) to 88%, but measles coverage (56%) remained inadequate for controlling the disease; Hib coverage was 20%. These results confirm that in Italy the coverage of only mandatory immunizations is satisfactory. Pertussis immunization coverage has improved dramatically since the introduction of acellular vaccines. A greater effort to educate parents and physicians is still needed to improve the coverage of optional vaccinations in all regions.

  1. [Typologies of Madrid's citizens (Spain) at the end-of-life: cluster analysis].

    PubMed

    Ortiz-Gonçalves, Belén; Perea-Pérez, Bernardo; Labajo González, Elena; Albarrán Juan, Elena; Santiago-Sáez, Andrés

    2018-03-06

    To establish typologies within Madrid's citizens (Spain) with regard to end-of-life by cluster analysis. The SPAD 8 programme was implemented in a sample from a health care centre in the autonomous region of Madrid (Spain). A multiple correspondence analysis technique was used, followed by a cluster analysis to create a dendrogram. A cross-sectional study was made beforehand with the results of the questionnaire. Five clusters stand out. Cluster 1: a group who preferred not to answer numerous questions (5%). Cluster 2: in favour of receiving palliative care and euthanasia (40%). Cluster 3: would oppose assisted suicide and would not ask for spiritual assistance (15%). Cluster 4: would like to receive palliative care and assisted suicide (16%). Cluster 5: would oppose assisted suicide and would ask for spiritual assistance (24%). The following four clusters stood out. Clusters 2 and 4 would like to receive palliative care, euthanasia (2) and assisted suicide (4). Clusters 4 and 5 regularly practiced their faith and their family members did not receive palliative care. Clusters 3 and 5 would be opposed to euthanasia and assisted suicide in particular. Clusters 2, 4 and 5 had not completed an advance directive document (2, 4 and 5). Clusters 2 and 3 seldom practiced their faith. This study could be taken into consideration to improve the quality of end-of-life care choices. Copyright © 2017 SESPAS. Publicado por Elsevier España, S.L.U. All rights reserved.

  2. HST Snapshot Study of Variable Stars in Globular Clusters: Inner Region of NGC 6441

    NASA Technical Reports Server (NTRS)

    Pritzl, Barton J.; Smith, Horace A.; Stetson, Peter B.; Catelan, Marcio; Sweigart, Allen V.; Layden, Andrew C.; Rich, R. Michael

    2003-01-01

    We present the results of a Hubble Space Telescope snapshot program to survey the inner region of the metal-rich globular cluster NGC 6441 for its variable stars. A total of 57 variable stars was found including 38 RR Lyrae stars, 6 Population II Cepheids, and 12 long period variables. Twenty-four of the RR Lyrae stars and all of the Population II Cepheids were previously undiscovered in ground-based surveys. Of the RR Lyrae stars observed in h s survey, 26 are pulsating in the fundamental mode with a mean period of 0.753 d and 12 are first-overtone mode pulsators with a mean period of 0.365 d. These values match up very well with those found in ground-based surveys. Combining all the available data for NGC 6441, we find mean periods of 0.759 d and 0.375 d for the RRab and RRc stars, respectively. We also find that the RR Lyrae in this survey are located in the same regions of a period-amplitude diagram as those found in ground-based surveys. The overall ratio of RRc to total RR Lyrae is 0.33. Although NGC 6441 is a metal-rich globular cluster and would, on that ground, be expected either to have few RR Lyrae stars, or to be an Oosterhoff type I system, its RR Lyrae more closely resemble those in Oosterhoff type II globular clusters. However, even compared to typical Oosterhoff type II systems, the mean period of its RRab stars is unusually long. We also derived I-band period-luminosity relations for the RR Lyrae stars. Of the six Population II Cepheids, five are of W Virginis type and one is a BL Herculis variable star. This makes NGC 6441, along with NGC 6388, the most metal-rich globular cluster known to contain these types of variable stars. Another variable, V118, may also be a Population II Cepheid given its long period and its separation in magnitude from the RR Lyrae stars. We examine the period-luminosity relation for these Population II Cepheids and compare it to those in other globular clusters and in the Large Magellanic Cloud. We argue that there does

  3. Assessing regional public health preparedness: a new tool for considering cross-border issues.

    PubMed

    Jones, Maggie; O'Carroll, Patrick; Thompson, Jack; D'Ambrosio, Luann

    2008-01-01

    To provide regional, state, and local public health officials a conceptual framework and checklist for assessing regional public health emergency preparedness, specifically in regard to cross-border public health preparedness needs. The project had four phases that are as follows: defining the scope, conducting a literature review, soliciting expert opinion, and creating the assessment framework and checklist. A conceptual framework was developed to define the scope of the project on the basis of the kinds of resources likely to be shared across borders in a public health response (eg, data, supplies, staff), in support of the public health functions likely to be important in a health emergency (eg, epidemiology, laboratory). A literature review was then conducted to identify key articles and tools addressing regional preparedness. Key informant interviews (n = 23) were conducted with public health and emergency management professionals in the Pacific Northwest to identify a set of systems, agreements, and protocols that should be systematically considered in assessing regional public health preparedness. Using the literature review and themes from interviews, a checklist was developed. A checklist was developed for use by public health leaders, which recommends 24 specific agreements, protocols, systems, and management structures that should be considered to foster cross-border public health preparedness. Regional public health preparedness represents not only the sum of state-level preparedness of the states in a region but also the capacity of those states to collaborate across state and international borders during a public health emergency. This checklist provides a tool to systematically consider cross-border preparedness issues.

  4. A Dozen New Galaxies Caught in the Act: Gas Stripping and Extended Emission Line Regions in the Coma Cluster

    NASA Astrophysics Data System (ADS)

    Yagi, Masafumi; Yoshida, Michitoshi; Komiyama, Yutaka; Kashikawa, Nobunari; Furusawa, Hisanori; Okamura, Sadanori; Graham, Alister W.; Miller, Neal A.; Carter, David; Mobasher, Bahram; Jogee, Shardha

    2010-12-01

    We present images of extended Hα clouds associated with 14 member galaxies in the Coma cluster obtained from deep narrowband imaging observations with the Suprime-Cam at the Subaru Telescope. The parent galaxies of the extended Hα clouds are distributed farther than 0.2 Mpc from the peak of the X-ray emission of the cluster. Most of the galaxies are bluer than g - r ≈ 0.5 and they account for 57% of the blue (g - r < 0.5) bright (r < 17.8 mag) galaxies in the central region of the Coma cluster. They reside near the red- and blueshifted edges of the radial velocity distribution of Coma cluster member galaxies. Our findings suggest that most of the parent galaxies were recently captured by the Coma cluster potential and are now infalling toward the cluster center with their disk gas being stripped off and producing the observed Hα clouds. Based on data collected at the Subaru Telescope, which is operated by the National Astronomical Observatory of Japan.

  5. Evaluation of data quality, timeliness and acceptability of the tuberculosis surveillance system in Brazil's micro-regions.

    PubMed

    Silva, Gabriela Drummond Marques da; Bartholomay, Patrícia; Cruz, Oswaldo Gonçalves; Garcia, Leila Posenato

    2017-10-01

    This study aimed to evaluate quality, acceptability and timeliness of the data in the tuberculosis surveillance system in Brazilian micro-regions. An ecological cross-sectional study was carried out, after a qualitative stage for selecting indicators. All 558 Brazilian micro-regions were used as units of analysis. Data available in the National Notifiable Diseases Information System (SINAN), from 2012 to 2014, were used to calculate 14 indicators relating to four attributes: completeness, consistency, timeliness and acceptability. The study made use of cluster analysis to group micro-regions according to acceptability and timeliness. Three clusters were identified among the 473 micro-regions with optimal or regular completeness (70% to 100%) and with over five notifications. Cluster 1 (n = 109) presented mean timeliness of notification and treatment equal to 62.8% and 24.9%, respectively. Cluster 2 (n = 143) had a mean percentage of cases tested for HIV equal to 55.9%. Cluster 3 (n = 221) had the best performing tuberculosis indicators. Results suggest priority areas for improving surveillance of tuberculosis, predominantly in the central-north part of the country. They also point to the need to increase the timeliness of treatment and the percentage of cases tested for HIV.

  6. Low-mass young stellar population and star formation history of the cluster IC 1805 in the W4 H II region

    NASA Astrophysics Data System (ADS)

    Panwar, Neelam; Samal, M. R.; Pandey, A. K.; Jose, J.; Chen, W. P.; Ojha, D. K.; Ogura, K.; Singh, H. P.; Yadav, R. K.

    2017-07-01

    W4 is a giant H II region ionized by the OB stars of the cluster IC 1805. The H II region/cluster complex has been a subject of numerous investigations as it is an excellent laboratory for studying the feedback effect of massive stars on the surrounding region. However, the low-mass stellar content of the cluster IC 1805 remains poorly studied till now. With the aim to unravel the low-mass stellar population of the cluster, we present the results of a multiwavelength study based on deep optical data obtained with the Canada-France-Hawaii Telescope, infrared data from Two Micron All Sky Survey and Spitzer Space Telescope and X-ray data from Chandra Space Telescope. The present optical data set is complete enough to detect stars down to 0.2 M⊙, which is the deepest optical observation so far for the cluster. We identified 384 candidate young stellar objects (YSOs; 101 Class I/II and 283 Class III) within the cluster using various colour-colour and colour-magnitude diagrams. We inferred the mean age of the identified YSOs to be ˜2.5 Myr and mass in the range 0.3-2.5 M⊙. The mass function of our YSO sample has a power-law index of -1.23 ± 0.23, close to the Salpeter value (-1.35), and consistent with those of other star-forming complexes. We explored the disc evolution of the cluster members and found that the disc-less sources are relatively older compared to the disc bearing YSO candidates. We examined the effect of high-mass stars on the circumstellar discs and within uncertainties, the influence of massive stars on the disc fraction seems to be insignificant. We also studied the spatial correlation of the YSOs with the distribution of gas and dust of the complex to conclude that IC 1805 would have formed in a large filamentary cloud.

  7. Regulatory Feedback Loop of Two phz Gene Clusters through 5′-Untranslated Regions in Pseudomonas sp. M18

    PubMed Central

    Li, Yaqian; Du, Xilin; Lu, Zhi John; Wu, Daqiang; Zhao, Yilei; Ren, Bin; Huang, Jiaofang; Huang, Xianqing; Xu, Yuhong; Xu, Yuquan

    2011-01-01

    Background Phenazines are important compounds produced by pseudomonads and other bacteria. Two phz gene clusters called phzA1-G1 and phzA2-G2, respectively, were found in the genome of Pseudomonas sp. M18, an effective biocontrol agent, which is highly homologous to the opportunistic human pathogen P. aeruginosa PAO1, however little is known about the correlation between the expressions of two phz gene clusters. Methodology/Principal Findings Two chromosomal insertion inactivated mutants for the two gene clusters were constructed respectively and the correlation between the expressions of two phz gene clusters was investigated in strain M18. Phenazine-1-carboxylic acid (PCA) molecules produced from phzA2-G2 gene cluster are able to auto-regulate expression itself and activate the expression of phzA1-G1 gene cluster in a circulated amplification pattern. However, the post-transcriptional expression of phzA1-G1 transcript was blocked principally through 5′-untranslated region (UTR). In contrast, the phzA2-G2 gene cluster was transcribed to a lesser extent and translated efficiently and was negatively regulated by the GacA signal transduction pathway, mainly at a post-transcriptional level. Conclusions/Significance A single molecule, PCA, produced in different quantities by the two phz gene clusters acted as the functional mediator and the two phz gene clusters developed a specific regulatory mechanism which acts through 5′-UTR to transfer a single, but complex bacterial signaling event in Pseudomonas sp. strain M18. PMID:21559370

  8. Electric potential structures of auroral acceleration region border from multi-spacecraft Cluster data

    NASA Astrophysics Data System (ADS)

    Sadeghi, S.; Emami, M. R.

    2018-04-01

    This paper studies an auroral event using data from three spacecraft of the Cluster mission, one inside and two at the poleward edge of the bottom of the Auroral Acceleration Region (AAR). The study reveals the three-dimensional profile of the region's poleward boundary, showing spatial segmentation of the electric potential structures and their decay in time. It also depicts localized magnetic field variations and field-aligned currents that appear to have remained stable for at least 80 s. Such observations became possible due to the fortuitous motion of the three spacecraft nearly parallel to each other and tangential to the AAR edge, so that the differences and variations can be seen when the spacecraft enter and exit the segmentations, hence revealing their position with respect to the AAR.

  9. Cross-national evidence for the clustering and psychosocial correlates of adolescent risk behaviours in 27 countries.

    PubMed

    de Looze, Margaretha; Ter Bogt, Tom F M; Raaijmakers, Quinten A W; Pickett, William; Kuntsche, Emmanuel; Vollebergh, Wilma A M

    2015-02-01

    According to Jessor's Problem Behaviour Theory (PBT) and Moffitt's theory of adolescence-limited antisocial behaviour, adolescent risk behaviours cluster and can be predicted by various psychosocial factors including parent, peer and school attachment. This study tested the potential influence of the sociocultural, or macro-level, environment on the clustering and correlates of adolescent risk behaviour across 27 European and North American countries. Analyses were based on data from the 2009-10 Health Behaviour in School-aged Children (HBSC) study. Participants compromised 56,090 adolescents (M(age) = 15.5 years) who self-reported on substance use (tobacco, alcohol, cannabis) and early sexual activity as well as on psychosocial factors (parent, peer and school attachment). Multiple group confirmatory factor analyses (with country as grouping variable) showed that substance use and early sexual activity loaded on a single underlying factor across countries. In addition, multiple group path analyses (with country as grouping variable) showed that associations between this factor and parent, peer and school attachment were identical across countries. Cross-national consistencies exist in the clustering and psychosocial correlates of substance use and early sexual activity across western countries. While Jessor's PBT stresses the problematic aspects of adolescent risk behaviours, Moffitt emphasizes their normative character. Although the problematic nature of risk behaviours overall receives more attention in the literature, it is important to consider both perspectives to fully understand why they cluster and correlate with psychosocial factors. This is essential for the development and implementation of prevention programmes aimed at reducing adolescent risk behaviours across Europe and North America. © The Author 2014. Published by Oxford University Press on behalf of the European Public Health Association. All rights reserved.

  10. Corrections for Cluster-Plot Slop

    Treesearch

    Harry T. Valentine; Mark J. Ducey; Jeffery H. Gove; Adrian Lanz; David L.R. Affleck

    2006-01-01

    Cluster-plot designs, including the design used by the Forest Inventory and Analysis program of the USDA Forest Service (FIA), are attended by a complicated boundary slopover problem. Slopover occurs where inclusion zones of objects of interest cross the boundary of the area of interest. The dispersed nature of inclusion zones that arise from the use of cluster plots...

  11. Recombinant dissection of myosin heavy chain of Toxocara canis shows strong clustering of antigenic regions.

    PubMed

    Obwaller, A; Duchêne, M; Bruhn, H; Steipe, B; Tripp, C; Kraft, D; Wiedermann, G; Auer, H; Aspöck, H

    2001-05-01

    Myosins from nematode parasites elicit strong humoral and cellular immune responses and have been investigated as vaccine candidates. In this study we cloned and sequenced a cDNA coding for myosin heavy chain from Toxocara canis, a nematode parasite of canids which may also infect humans and cause various unspecific symptoms. To determine the major antigenic regions the myosin heavy chain was systematically dissected into ten overlapping recombinant fusion polypeptides which were purified by metal chelate chromatography. Single fragments were then tested for their IgG reactivity in sera from toxocarosis patients and healthy probands. Two regions, one region at the mid to carboxy-terminal end of the head domain and one region in the rod domain, were identified as major antigens, which in combination were positive with 86% of the sera. The other domains were less reactive. This shows that the patients' IgG reactivity was not directed evenly against all parts of the molecule, but was rather clustered in few regions.

  12. Statistical detection of geographic clusters of resistant Escherichia coli in a regional network with WHONET and SaTScan.

    PubMed

    Park, Rachel; O'Brien, Thomas F; Huang, Susan S; Baker, Meghan A; Yokoe, Deborah S; Kulldorff, Martin; Barrett, Craig; Swift, Jamie; Stelling, John

    2016-11-01

    While antimicrobial resistance threatens the prevention, treatment, and control of infectious diseases, systematic analysis of routine microbiology laboratory test results worldwide can alert new threats and promote timely response. This study explores statistical algorithms for recognizing geographic clustering of multi-resistant microbes within a healthcare network and monitoring the dissemination of new strains over time. Escherichia coli antimicrobial susceptibility data from a three-year period stored in WHONET were analyzed across ten facilities in a healthcare network utilizing SaTScan's spatial multinomial model with two models for defining geographic proximity. We explored geographic clustering of multi-resistance phenotypes within the network and changes in clustering over time. Geographic clustering identified from both latitude/longitude and non-parametric facility groupings geographic models were similar, while the latter was offers greater flexibility and generalizability. Iterative application of the clustering algorithms suggested the possible recognition of the initial appearance of invasive E. coli ST131 in the clinical database of a single hospital and subsequent dissemination to others. Systematic analysis of routine antimicrobial resistance susceptibility test results supports the recognition of geographic clustering of microbial phenotypic subpopulations with WHONET and SaTScan, and iterative application of these algorithms can detect the initial appearance in and dissemination across a region prompting early investigation, response, and containment measures.

  13. Cooperation control strategies for China's cross-region pollution in a lake basin based on green reduction cost.

    PubMed

    Li, Changmin; Sun, Dong; Xie, Xiaoqiang; Xue, Jian

    2016-05-01

    The cross-region water pollution issue has always been the widespread concern around the world. It becomes especially critical for China due to the imbalance relates to environmental costs that have accompanied rapid growth of economy. Though the government makes great efforts to improve it, the potential for water pollution conflict is still great. We consider the problem of determining combined control strategies for China's cross-region lake pollution based on the environmental green costs. The problem is first formulated as a generalized bilevel mathematical program where the upper level consists in each region that reduces environmental green costs including three parts: the reduction cost, pollution permit trade cost and cost of environment damage, while the lower level is represented by pollution permit equilibrium market. Finally, we take an empirical analysis in Taihu lake. The numerical study shows that the minimum costs of both total and regional are obviously superior to the current processing costs, which provides theoretical basis for the price of emission permits. Today, China's rapid gross domestic product (GDP) growth has come at a very high cost, as real estate prices have skyrocketed, the wealth gap has widened, and environmental pollution has worsened. China's central government is urged to correct the GDP-oriented performance evaluation system that is used to judge administrative region leaders. The cross-region water pollution issue has become a troubling issue that urgently needs to be resolved in China. This paper will not only actively aid efforts to govern Lake Taihu and other cross-region valleys, but it will also provide a supplement for theoretical research on cross-region pollution issues.

  14. Detecting cancer clusters in a regional population with local cluster tests and Bayesian smoothing methods: a simulation study

    PubMed Central

    2013-01-01

    Background There is a rising public and political demand for prospective cancer cluster monitoring. But there is little empirical evidence on the performance of established cluster detection tests under conditions of small and heterogeneous sample sizes and varying spatial scales, such as are the case for most existing population-based cancer registries. Therefore this simulation study aims to evaluate different cluster detection methods, implemented in the open soure environment R, in their ability to identify clusters of lung cancer using real-life data from an epidemiological cancer registry in Germany. Methods Risk surfaces were constructed with two different spatial cluster types, representing a relative risk of RR = 2.0 or of RR = 4.0, in relation to the overall background incidence of lung cancer, separately for men and women. Lung cancer cases were sampled from this risk surface as geocodes using an inhomogeneous Poisson process. The realisations of the cancer cases were analysed within small spatial (census tracts, N = 1983) and within aggregated large spatial scales (communities, N = 78). Subsequently, they were submitted to the cluster detection methods. The test accuracy for cluster location was determined in terms of detection rates (DR), false-positive (FP) rates and positive predictive values. The Bayesian smoothing models were evaluated using ROC curves. Results With moderate risk increase (RR = 2.0), local cluster tests showed better DR (for both spatial aggregation scales > 0.90) and lower FP rates (both < 0.05) than the Bayesian smoothing methods. When the cluster RR was raised four-fold, the local cluster tests showed better DR with lower FPs only for the small spatial scale. At a large spatial scale, the Bayesian smoothing methods, especially those implementing a spatial neighbourhood, showed a substantially lower FP rate than the cluster tests. However, the risk increases at this scale were mostly diluted by data

  15. Regional Patterns and Spatial Clusters of Nonstationarities in Annual Peak Instantaneous Streamflow

    NASA Astrophysics Data System (ADS)

    White, K. D.; Baker, B.; Mueller, C.; Villarini, G.; Foley, P.; Friedman, D.

    2017-12-01

    Information about hydrologic changes resulting from changes in climate, land use, and land cover is a necessity planning and design or water resources infrastructure. The United States Army Corps of Engineers (USACE) evaluated and selected 12 methods to detect abrupt and slowly varying nonstationarities in records of maximum peak annual flows. They deployed a publicly available tool[1]in 2016 and a guidance document in 2017 to support identification of nonstationarities in a reproducible manner using a robust statistical framework. This statistical framework has now been applied to streamflow records across the continental United States to explore the presence of regional patterns and spatial clusters of nonstationarities in peak annual flow. Incorporating this geographic dimension into the detection of nonstationarities provides valuable insight for the process of attribution of these significant changes. This poster summarizes the methods used and provides the results of the regional analysis. [1] Available here - http://www.corpsclimate.us/ptcih.cfm

  16. Variability of ULF wave power at the magnetopause: a study at low latitude with Cluster data

    NASA Astrophysics Data System (ADS)

    Cornilleau-Wehrlin, N.; Grison, B.; Belmont, G.; Rezeau, L.; Chanteur, G.; Robert, P.; Canu, P.

    2012-04-01

    Strong ULF wave activity has been observed at magnetopause crossings since a long time. Those turbulent-like waves are possible contributors to particle penetration from the Solar Wind to the Magnetosphere through the magnetopause. Statistical studies have been performed to understand under which conditions the ULF wave power is the most intense and thus the waves can be the most efficient for particle transport from one region to the other. Clearly the solar wind pressure organizes the data, the stronger the pressure, the higher the ULF power (Attié et al 2008). Double STAR-Cluster comparison has shown that ULF wave power is stronger at low latitude than at high latitude (Cornilleau-Wehrlin et al, 2008). The different studies performed have not, up to now, shown a stronger power in the vicinity of local noon. Nevertheless under identical activity conditions, the variability of this power, even at a given location in latitude and local time is very high. The present work intends at understanding this variability by means of the multi spacecraft mission Cluster. The data used are from spring 2008, while Cluster was crossing the magnetopause at low latitude, in particularly quite Solar Wind conditions. The first region of interest of this study is the sub-solar point vicinity where the long wavelength surface wave effects are most unlikely.

  17. Globular clusters and environmental effects in galaxy clusters

    NASA Astrophysics Data System (ADS)

    Sales, Laura

    2016-10-01

    Globular clusters are old compact stellar systems orbiting around galaxies of all types. Tens of thousands of them can also be found populating the intra-cluster regions of nearby galaxy clusters like Virgo and Coma. Thanks to the HST Frontier Fields program, GCs are starting now to be detected also in intermediate redshift clusters. Yet, despite their ubiquity, a theoretical model for the formation and evolution of GCs is still missing, especially within the cosmological context.Here we propose to use cosmological hydrodynamical simulations of 18 galaxy clusters coupled to a post-processing GC formation model to explore the assembly of galaxies in clusters together with their expected GC population. The method, which has already been implemented and tested, will allow us to characterize for the first time the number, radial distribution and kinematics of GCs in clusters, with products directly comparable to observational maps. We will explore cluster-to-cluster variations and also characterize the build up of the intra-cluster component of GCs with time.As the method relies on a detailed study of the star-formation history of galaxies, we will jointly constrain the predicted quenching time-scales for satellites and the occurrence of starburst events associated to infall and orbital pericenters of galaxies in massive clusters. This will inform further studies on the distribution, velocity and properties of post-starburst galaxies in past, ongoing and future HST programs.

  18. SEARCHING FOR COOLING SIGNATURES IN STRONG LENSING GALAXY CLUSTERS: EVIDENCE AGAINST BARYONS SHAPING THE MATTER DISTRIBUTION IN CLUSTER CORES

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Blanchard, Peter K.; Bayliss, Matthew B.; McDonald, Michael

    2013-07-20

    The process by which the mass density profile of certain galaxy clusters becomes centrally concentrated enough to produce high strong lensing (SL) cross-sections is not well understood. It has been suggested that the baryonic condensation of the intracluster medium (ICM) due to cooling may drag dark matter to the cores and thus steepen the profile. In this work, we search for evidence of ongoing ICM cooling in the first large, well-defined sample of SL selected galaxy clusters in the range 0.1 < z < 0.6. Based on known correlations between the ICM cooling rate and both optical emission line luminositymore » and star formation, we measure, for a sample of 89 SL clusters, the fraction of clusters that have [O II]{lambda}{lambda}3727 emission in their brightest cluster galaxy (BCG). We find that the fraction of line-emitting BCGs is constant as a function of redshift for z > 0.2 and shows no statistically significant deviation from the total cluster population. Specific star formation rates, as traced by the strength of the 4000 A break, D{sub 4000}, are also consistent with the general cluster population. Finally, we use optical imaging of the SL clusters to measure the angular separation, R{sub arc}, between the arc and the center of mass of each lensing cluster in our sample and test for evidence of changing [O II] emission and D{sub 4000} as a function of R{sub arc}, a proxy observable for SL cross-sections. D{sub 4000} is constant with all values of R{sub arc}, and the [O II] emission fractions show no dependence on R{sub arc} for R{sub arc} > 10'' and only very marginal evidence of increased weak [O II] emission for systems with R{sub arc} < 10''. These results argue against the ability of baryonic cooling associated with cool core activity in the cores of galaxy clusters to strongly modify the underlying dark matter potential, leading to an increase in SL cross-sections.« less

  19. Rotation curves of spiral galaxies in clusters

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Whitmore, B.C.

    1990-06-01

    Recent observations of rotation curves of spiral galaxies in clusters made by Rubin et al. (1988), Whitmore et al. (1988) and Forbes and Whitmore (1988) are analyzed. It is found that spiral galaxies in the inner region of clusters appear to have falling rotation curves and M/L gradients which are flatter than for galaxies in the outer regions of clusters. Problems encountered in attempts to construct mass models for cluster galaxies are briefly discussed. 18 refs.

  20. Collision-induced dissociation of protonated water clusters

    NASA Astrophysics Data System (ADS)

    Berthias, F.; Buridon, V.; Abdoul-Carime, H.; Farizon, B.; Farizon, M.; Dinh, P. M.; Reinhard, P.-G.; Suraud, E.; Märk, T. D.

    2014-06-01

    Collision-induced dissociation (CID) has been studied for protonated water clusters H+(H2O)n, with n = 2-8, colliding with argon atoms at a laboratory energy of 8 keV. The experimental data have been taken with an apparatus (Device for Irradiation of Molecular Clusters, `Dispositif d'Irradiation d'Agrégats Moléculaire,' DIAM) that has been recently constructed at the Institut de Physique Nucléaire de Lyon. It includes an event-by-event mass spectrometry detection technique, COINTOF (correlated ion and neutral fragment time of flight). The latter device allows, for each collision event, to detect and identify in a correlated manner all produced neutral and charged fragments. For all the studied cluster ions, it has allowed us to identify branching ratios for the loss of i = 1 to i = n water molecules, leading to fragment ions ranging from H+(H2O)i=n-1 all the way down to the production of protons. Using a corresponding calibration technique we determine total charged fragment production cross sections for incident protonated water clusters H+(H2O)n, with n = 2-7. Observed trends for branching ratios and cross sections, and a comparison with earlier data on measured attenuation cross sections for water clusters colliding with other noble gases (He and Xe), give insight into the underlying dissociation mechanisms.

  1. Failure of lysosome clustering and positioning in the juxtanuclear region in cells deficient in rapsyn

    PubMed Central

    Aittaleb, Mohamed; Chen, Po-Ju; Akaaboune, Mohammed

    2015-01-01

    ABSTRACT Rapsyn, a scaffold protein, is required for the clustering of acetylcholine receptors (AChRs) at contacts between motor neurons and differentiating muscle cells. Rapsyn is also expressed in cells that do not express AChRs. However, its function in these cells remains unknown. Here, we show that rapsyn plays an AChR-independent role in organizing the distribution and mobility of lysosomes. In cells devoid of AChRs, rapsyn selectively induces the clustering of lysosomes at high density in the juxtanuclear region without affecting the distribution of other intracellular organelles. However, when the same cells overexpress AChRs, rapsyn is recruited away from lysosomes to colocalize with AChR clusters on the cell surface. In rapsyn-deficient (Rapsn−/−) myoblasts or cells overexpressing rapsyn mutants, lysosomes are scattered within the cell and highly dynamic. The increased mobility of lysosomes in Rapsn−/− cells is associated with a significant increase in lysosomal exocytosis, as evidenced by increased release of lysosomal enzymes and plasma membrane damage when cells were challenged with the bacterial pore-forming toxin streptolysin-O. These findings uncover a new link between rapsyn, lysosome positioning, exocytosis and plasma membrane integrity. PMID:26330529

  2. Stability-based validation of dietary patterns obtained by cluster analysis.

    PubMed

    Sauvageot, Nicolas; Schritz, Anna; Leite, Sonia; Alkerwi, Ala'a; Stranges, Saverio; Zannad, Faiez; Streel, Sylvie; Hoge, Axelle; Donneau, Anne-Françoise; Albert, Adelin; Guillaume, Michèle

    2017-01-14

    Cluster analysis is a data-driven method used to create clusters of individuals sharing similar dietary habits. However, this method requires specific choices from the user which have an influence on the results. Therefore, there is a need of an objective methodology helping researchers in their decisions during cluster analysis. The objective of this study was to use such a methodology based on stability of clustering solutions to select the most appropriate clustering method and number of clusters for describing dietary patterns in the NESCAV study (Nutrition, Environment and Cardiovascular Health), a large population-based cross-sectional study in the Greater Region (N = 2298). Clustering solutions were obtained with K-means, K-medians and Ward's method and a number of clusters varying from 2 to 6. Their stability was assessed with three indices: adjusted Rand index, Cramer's V and misclassification rate. The most stable solution was obtained with K-means method and a number of clusters equal to 3. The "Convenient" cluster characterized by the consumption of convenient foods was the most prevalent with 46% of the population having this dietary behaviour. In addition, a "Prudent" and a "Non-Prudent" patterns associated respectively with healthy and non-healthy dietary habits were adopted by 25% and 29% of the population. The "Convenient" and "Non-Prudent" clusters were associated with higher cardiovascular risk whereas the "Prudent" pattern was associated with a decreased cardiovascular risk. Associations with others factors showed that the choice of a specific dietary pattern is part of a wider lifestyle profile. This study is of interest for both researchers and public health professionals. From a methodological standpoint, we showed that using stability of clustering solutions could help researchers in their choices. From a public health perspective, this study showed the need of targeted health promotion campaigns describing the benefits of healthy

  3. Visualizing Confidence in Cluster-Based Ensemble Weather Forecast Analyses.

    PubMed

    Kumpf, Alexander; Tost, Bianca; Baumgart, Marlene; Riemer, Michael; Westermann, Rudiger; Rautenhaus, Marc

    2018-01-01

    In meteorology, cluster analysis is frequently used to determine representative trends in ensemble weather predictions in a selected spatio-temporal region, e.g., to reduce a set of ensemble members to simplify and improve their analysis. Identified clusters (i.e., groups of similar members), however, can be very sensitive to small changes of the selected region, so that clustering results can be misleading and bias subsequent analyses. In this article, we - a team of visualization scientists and meteorologists-deliver visual analytics solutions to analyze the sensitivity of clustering results with respect to changes of a selected region. We propose an interactive visual interface that enables simultaneous visualization of a) the variation in composition of identified clusters (i.e., their robustness), b) the variability in cluster membership for individual ensemble members, and c) the uncertainty in the spatial locations of identified trends. We demonstrate that our solution shows meteorologists how representative a clustering result is, and with respect to which changes in the selected region it becomes unstable. Furthermore, our solution helps to identify those ensemble members which stably belong to a given cluster and can thus be considered similar. In a real-world application case we show how our approach is used to analyze the clustering behavior of different regions in a forecast of "Tropical Cyclone Karl", guiding the user towards the cluster robustness information required for subsequent ensemble analysis.

  4. Statistical detection of geographic clusters of resistant Escherichia coli in a regional network with WHONET and SaTScan

    PubMed Central

    Park, Rachel; O'Brien, Thomas F.; Huang, Susan S.; Baker, Meghan A.; Yokoe, Deborah S.; Kulldorff, Martin; Barrett, Craig; Swift, Jamie; Stelling, John

    2016-01-01

    Objectives While antimicrobial resistance threatens the prevention, treatment, and control of infectious diseases, systematic analysis of routine microbiology laboratory test results worldwide can alert new threats and promote timely response. This study explores statistical algorithms for recognizing geographic clustering of multi-resistant microbes within a healthcare network and monitoring the dissemination of new strains over time. Methods Escherichia coli antimicrobial susceptibility data from a three-year period stored in WHONET were analyzed across ten facilities in a healthcare network utilizing SaTScan's spatial multinomial model with two models for defining geographic proximity. We explored geographic clustering of multi-resistance phenotypes within the network and changes in clustering over time. Results Geographic clustering identified from both latitude/longitude and non-parametric facility groupings geographic models were similar, while the latter was offers greater flexibility and generalizability. Iterative application of the clustering algorithms suggested the possible recognition of the initial appearance of invasive E. coli ST131 in the clinical database of a single hospital and subsequent dissemination to others. Conclusion Systematic analysis of routine antimicrobial resistance susceptibility test results supports the recognition of geographic clustering of microbial phenotypic subpopulations with WHONET and SaTScan, and iterative application of these algorithms can detect the initial appearance in and dissemination across a region prompting early investigation, response, and containment measures. PMID:27530311

  5. Flare Clustering

    NASA Astrophysics Data System (ADS)

    Title, Alan; DeRosa, Marc

    2016-10-01

    The continuous full disk observations provided by the Atmospheric Imaging Assembly (AIA ) can give an observer the impression that many flare eruptions are causally related to one another. However, both detailed analyses of a number of events as well as several statistical studies have provided only rare examples or weak evidence of causal behavior. Since the mechanisms of flare triggering are not well understood, the lack of hard evidence is not surprising. For this study we looked instead for groups of flares (flare clusters) in which successive flares occur within a fixed time - the selection time. The data set used for the investigation is the flare waiting times provided by the X-ray flare detectors on the Geostationary Operational Environmental Satellites (GOES). We limited the study to flares of magnitude C5 and greater obtained during cycles 21, 22, 23, and 24. The GOES field of view includes the entire visible surface. While many flares in a cluster may come from the same active region, the larger clusters often have origins in multiple regions. The longest C5 cluster found with a linking window of 36 hours in cycles 21, 22, 23,and 24 was 54, 82, 42, and 18 days, respectively. X flares also cluster. A superposed epoch analyses demonstrates that there is a pronounced enhancement of number of C5 and and above flares that are centered on the X flare clusters. We suggest that this behavior implies that a component of the observed coordinated behavior originates from the MHD processes driven by the solar dynamo that in turn creates unstable states in the solar atmosphere. The relationship between flare clusters and magnetic centers of activity was explored as was the correlation between high flare rates and significant changes in the total solar magnetic flux,

  6. Measurements of absolute absorption cross sections of ozone in the 185- to 254-nm wavelength region and the temperature dependence

    NASA Technical Reports Server (NTRS)

    Yoshino, K.; Esmond, J. R.; Freeman, D. E.; Parkinson, W. H.

    1993-01-01

    Laboratory measurements of the relative absorption cross sections of ozone at temperatures 195, 228, and 295 K have been made throughout the 185 to 254 nm wavelength region. The absolute absorption cross sections at the same temperatures have been measured at several discrete wavelengths in the 185 to 250 nm region. The absolute cross sections of ozone have been used to put the relative cross sections on a firm absolute basis throughout the 185 to 255 nm region. These recalibrated cross sections are slightly lower than those of Molina and Molina (1986), but the differences are within a few percent and would not be significant in atmospheric applications.

  7. Health-Related Quality of Life and Lifestyle Behavior Clusters in School-Aged Children from 12 Countries.

    PubMed

    Dumuid, Dorothea; Olds, Timothy; Lewis, Lucy K; Martin-Fernández, Josep Antoni; Katzmarzyk, Peter T; Barreira, Tiago; Broyles, Stephanie T; Chaput, Jean-Philippe; Fogelholm, Mikael; Hu, Gang; Kuriyan, Rebecca; Kurpad, Anura; Lambert, Estelle V; Maia, José; Matsudo, Victor; Onywera, Vincent O; Sarmiento, Olga L; Standage, Martyn; Tremblay, Mark S; Tudor-Locke, Catrine; Zhao, Pei; Gillison, Fiona; Maher, Carol

    2017-04-01

    To evaluate the relationship between children's lifestyles and health-related quality of life and to explore whether this relationship varies among children from different world regions. This study used cross-sectional data from the International Study of Childhood Obesity, Lifestyle and the Environment. Children (9-11 years) were recruited from sites in 12 nations (n = 5759). Clustering input variables were 24-hour accelerometry and self-reported diet and screen time. Health-related quality of life was self-reported with KIDSCREEN-10. Cluster analyses (using compositional analysis techniques) were performed on a site-wise basis. Lifestyle behavior cluster characteristics were compared between sites. The relationship between cluster membership and health-related quality of life was assessed with the use of linear models. Lifestyle behavior clusters were similar across the 12 sites, with clusters commonly characterized by (1) high physical activity (actives); (2) high sedentary behavior (sitters); (3) high screen time/unhealthy eating pattern (junk-food screenies); and (4) low screen time/healthy eating pattern and moderate physical activity/sedentary behavior (all-rounders). Health-related quality of life was greatest in the all-rounders cluster. Children from different world regions clustered into groups of similar lifestyle behaviors. Cluster membership was related to differing health-related quality of life, with children from the all-rounders cluster consistently reporting greatest health-related quality of life at sites around the world. Findings support the importance of a healthy combination of lifestyle behaviors in childhood: low screen time, healthy eating pattern, and balanced daily activity behaviors (physical activity and sedentary behavior). ClinicalTrials.gov: NCT01722500. Copyright © 2016 Elsevier Inc. All rights reserved.

  8. Cluster analysis applied to localized dispersion curves in East Asia: the limits of surface wave resolution

    NASA Astrophysics Data System (ADS)

    Witek, M.; van der Lee, S.; Kang, T. S.; Chang, S. J.; Ning, J.; Ning, S.

    2017-12-01

    We have measured Rayleigh wave group velocity dispersion curves from one year of station-pair cross-correlations of continuous vertical-component broadband data from 1082 seismic stations in regional networks across China, Korea, Taiwan, and Japan for the year 2011. We use the measurements to map local dispersion anomalies for periods in the range 6-40 s. We combined our ambient noise data set with the earthquake group velocity data set of Ma et al. (2014), and then applied agglomerative hierarchical clustering to the localized dispersion curves. We find that the dispersion curves naturally organize themselves into distinct tectonic regions. For our distribution of interstation distances, only 8 distinct regions need to be defined. Additional clusters reduce the overall data misfit by increasingly smaller amounts. The size and number of clusters needed to suitably predict the data may give an indication of the resolving power of the data set. The regions that emerge from the cluster analysis include Tibet, the Sea of Japan, the South China Block and the Korean peninsula, the Ordos and Yangtze cratons, and Mesozoic rift basins such as the Songliao, Bohai Bay and Ulleung basins. We also performed a traditional inversion for 3D S-velocity structure, and the resulting model fits the data as well as the 8-cluster model, while both models fit the earthquake data and ambient noise data better than the LITHO1.0 model of Pasyanos et al. (2014). Our 3D model of the crust and upper mantle confirms many of the features seen in previous studies of the region, most notably the lithospheric thinning going from west to east and low velocity zones in the crust on the Tibetan periphery. We conclude that cluster analysis is able to greatly reduce the dimensionality of surface wave dispersion data, in the sense that a data set of over half a million dispersion curves is sufficiently predicted by appropriately averaging over a relatively small set of distinct tectonic regions. The

  9. Conversion events in gene clusters

    PubMed Central

    2011-01-01

    Background Gene clusters containing multiple similar genomic regions in close proximity are of great interest for biomedical studies because of their associations with inherited diseases. However, such regions are difficult to analyze due to their structural complexity and their complicated evolutionary histories, reflecting a variety of large-scale mutational events. In particular, conversion events can mislead inferences about the relationships among these regions, as traced by traditional methods such as construction of phylogenetic trees or multi-species alignments. Results To correct the distorted information generated by such methods, we have developed an automated pipeline called CHAP (Cluster History Analysis Package) for detecting conversion events. We used this pipeline to analyze the conversion events that affected two well-studied gene clusters (α-globin and β-globin) and three gene clusters for which comparative sequence data were generated from seven primate species: CCL (chemokine ligand), IFN (interferon), and CYP2abf (part of cytochrome P450 family 2). CHAP is freely available at http://www.bx.psu.edu/miller_lab. Conclusions These studies reveal the value of characterizing conversion events in the context of studying gene clusters in complex genomes. PMID:21798034

  10. THE DYNAMICS OF MERGING CLUSTERS: A MONTE CARLO SOLUTION APPLIED TO THE BULLET AND MUSKET BALL CLUSTERS

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Dawson, William A., E-mail: wadawson@ucdavis.edu

    2013-08-01

    Merging galaxy clusters have become one of the most important probes of dark matter, providing evidence for dark matter over modified gravity and even constraints on the dark matter self-interaction cross-section. To properly constrain the dark matter cross-section it is necessary to understand the dynamics of the merger, as the inferred cross-section is a function of both the velocity of the collision and the observed time since collision. While the best understanding of merging system dynamics comes from N-body simulations, these are computationally intensive and often explore only a limited volume of the merger phase space allowed by observed parametermore » uncertainty. Simple analytic models exist but the assumptions of these methods invalidate their results near the collision time, plus error propagation of the highly correlated merger parameters is unfeasible. To address these weaknesses I develop a Monte Carlo method to discern the properties of dissociative mergers and propagate the uncertainty of the measured cluster parameters in an accurate and Bayesian manner. I introduce this method, verify it against an existing hydrodynamic N-body simulation, and apply it to two known dissociative mergers: 1ES 0657-558 (Bullet Cluster) and DLSCL J0916.2+2951 (Musket Ball Cluster). I find that this method surpasses existing analytic models-providing accurate (10% level) dynamic parameter and uncertainty estimates throughout the merger history. This, coupled with minimal required a priori information (subcluster mass, redshift, and projected separation) and relatively fast computation ({approx}6 CPU hours), makes this method ideal for large samples of dissociative merging clusters.« less

  11. The Peculiarities in O-Type Galaxy Clusters

    NASA Astrophysics Data System (ADS)

    Panko, E. A.; Emelyanov, S. I.

    We present the results of analysis of 2D distribution of galaxies in galaxy cluster fields. The Catalogue of Galaxy Clusters and Groups PF (Panko & Flin) was used as input observational data set. We selected open rich PF galaxy clusters, containing 100 and more galaxies for our study. According to Panko classification scheme open galaxy clusters (O-type) have no concentration to the cluster center. The data set contains both pure O-type clusters and O-type clusters with overdence belts, namely OL and OF types. According to Rood & Sastry and Struble & Rood ideas, the open galaxy clusters are the beginning stage of cluster evolution. We found in the O-type clusters some types of statistically significant regular peculiarities, such as two crossed belts or curved strip. We suppose founded features connected with galaxy clusters evolution and the distribution of DM inside the clusters.

  12. Spectroscopy of the Perseus Cluster

    NASA Technical Reports Server (NTRS)

    Jones, Christine; Mushotzky, Richard F. (Technical Monitor)

    2004-01-01

    We present preliminary results of a XMM-Newton 50 ks observation of the Perseus Cluster that provides an unprecedented view of the central 0.5 Mpc region. The projected gas temperature declines smoothly by a factor of 2 from a maximum value of approx. 7 keV in the outer regions to just above 3 keV at the cluster center. Over this same range, the heavy-element abundance rises slowly from 0.4 to 0.5 solar as the radius decreases from 14 ft. to 5 ft., and then it rises to a peak of almost 0.7 solar at 1&farcm;25 before declining to 0.4 at the center. Th global east-west asymmetry of the gas temperature and surface brightness distributions, approximately aligned with the chain of bright galaxies, suggests an ongoing merger, although the modest degree of the observed asymmetry certainly excludes a major merger interpretation. The chain of galaxies probably traces the filament along which accretion started some time ago and is continuing at the present time. A cold and dense (low-entropy) cluster core like Perseus is probably well "protected" against the penetration of the gas of infalling groups and poor clusters, whereas in non-cooling core clusters such as Coma and A1367, infalling subclusters can penetrate deeply into the core region. In Perseus, gas associated with infalling groups may be stripped completely at the outskirts of the main cluster and only compression waves (shocks) may reach the central regions. We argue, and show supporting simulations, that the passage of such a wave(s) can qualitatively explain the overall horseshoe shaped appearance of the gas temperature map (the hot horseshoe surrounds the colder, low-entropy core) as well as other features of the Perseus Cluster core. These simulations also show that as compression waves traverse the cluster core, they can induce oscillatory motion of the cluster gas that can generate multiple sharp "edges" on opposite sides of the central galaxy. Gas motions induced by mergers may be a natural way to explain

  13. A high-significance measurement of correlation between unresolved IRAS sources and optically-selected galaxy clusters

    NASA Astrophysics Data System (ADS)

    Hincks, Adam D.; Hajian, Amir; Addison, Graeme E.

    2013-05-01

    We cross-correlate the 100 μm Improved Reprocessing of the IRAS Survey (IRIS) map and galaxy clusters at 0.1 < z < 0.3 in the maxBCG catalogue taken from the Sloan Digital Sky Survey, measuring an angular cross-power spectrum over multipole moments 150 < l < 3000 at a total significance of over 40σ. The cross-spectrum, which arises from the spatial correlation between unresolved dusty galaxies that make up the cosmic infrared background (CIB) in the IRIS map and the galaxy clusters, is well-fit by a single power law with an index of -1.28±0.12, similar to the clustering of unresolved galaxies from cross-correlating far-infrared and submillimetre maps at longer wavelengths. Using a recent, phenomenological model for the spectral and clustering properties of the IRIS galaxies, we constrain the large-scale bias of the maxBCG clusters to be 2.6±1.4, consistent with existing analyses of the real-space cluster correlation function. The success of our method suggests that future CIB-optical cross-correlations using Planck and Herschel data will significantly improve our understanding of the clustering and redshift distribution of the faint CIB sources.

  14. Infrared Coronet Cluster

    NASA Image and Video Library

    2007-09-13

    This image from NASA Spitzer Space Telescope shows young stars plus diffuse emission from dust. The Corona Australis region containing, at its heart, the Coronet cluster is one of the nearest and most active regions of ongoing star formation.

  15. SERA Scenarios of Early Market Fuel Cell Electric Vehicle Introductions: Modeling Framework, Regional Markets, and Station Clustering

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bush, B.; Melaina, M.; Penev, M.

    This report describes the development and analysis of detailed temporal and spatial scenarios for early market hydrogen fueling infrastructure clustering and fuel cell electric vehicle rollout using the Scenario Evaluation, Regionalization and Analysis (SERA) model. The report provides an overview of the SERA scenario development framework and discusses the approach used to develop the nationwidescenario.

  16. Star clusters in the Magellanic Clouds - I. Parametrization and classification of 1072 clusters in the LMC

    NASA Astrophysics Data System (ADS)

    Nayak, P. K.; Subramaniam, A.; Choudhury, S.; Indu, G.; Sagar, Ram

    2016-12-01

    We have introduced a semi-automated quantitative method to estimate the age and reddening of 1072 star clusters in the Large Magellanic Cloud (LMC) using the Optical Gravitational Lensing Experiment III survey data. This study brings out 308 newly parametrized clusters. In a first of its kind, the LMC clusters are classified into groups based on richness/mass as very poor, poor, moderate and rich clusters, similar to the classification scheme of open clusters in the Galaxy. A major cluster formation episode is found to happen at 125 ± 25 Myr in the inner LMC. The bar region of the LMC appears prominently in the age range 60-250 Myr and is found to have a relatively higher concentration of poor and moderate clusters. The eastern and the western ends of the bar are found to form clusters initially, which later propagates to the central part. We demonstrate that there is a significant difference in the distribution of clusters as a function of mass, using a movie based on the propagation (in space and time) of cluster formation in various groups. The importance of including the low-mass clusters in the cluster formation history is demonstrated. The catalogue with parameters, classification, and cleaned and isochrone fitted colour-magnitude diagrams of 1072 clusters, which are available as online material, can be further used to understand the hierarchical formation of clusters in selected regions of the LMC.

  17. Starburst clusters in the Galactic center

    NASA Astrophysics Data System (ADS)

    Habibi, Maryam

    2014-09-01

    The central region of the Galaxy is the most active site of star formation in the Milky Way, where massive stars have formed very recently and are still forming today. The rich population of massive stars in the Galactic center provide a unique opportunity to study massive stars in their birth environment and probe their initial mass function, which is the spectrum of stellar masses at their birth. The Arches cluster is the youngest among the three massive clusters in the Galactic center, providing a collection of high-mass stars and a very dense core which makes this cluster an excellent site to address questions about massive star formation, the stellar mass function and the dynamical evolution of massive clusters in the Galactic center. In this thesis, I perform an observational study of the Arches cluster using K_{s}-band imaging obtained with NAOS/CONICA at the VLT combined with Subaru/Cisco J-band data to gain a full understanding of the cluster mass distribution out to its tidal radius for the first time. Since the light from the Galactic center reaches us through the Galactic disc, the extinction correction is crucial when studying this region. I use a Bayesian method to construct a realistic extinction map of the cluster. It is shown in this study that the determination of the mass of the most massive star in the Arches cluster, which had been used in previous studies to establish an upper mass limit for the star formation process in the Milky Way, strongly depends on the assumed slope of the extinction law. Assuming the two regimes of widely used infrared extinction laws, I show that the difference can reach up to 30% for individually derived stellar masses and Δ A_{Ks}˜ 1 magnitude in acquired K_{s}-band extinction, while the present-day mass function slope changes by ˜ 0.17 dex. The present-day mass function slope derived assuming the more recent extinction law, which suggests a steeper wavelength dependence for the infrared extinction law, reveals

  18. Dolidze-35: Results for a Possible Open Cluster

    NASA Astrophysics Data System (ADS)

    Gulledge, Deborah J.; Borges, Richard A.; Juelfs, Elizabeth; Allyn Smith, J.; Olive, Mary E.; McDonald, Christopher P.; Williams, Sarah M.; Cohen, Eden M.; Gawel, Jason D.; McCole, Bambi A.; Robertson, Jacob M.; Wilson, Tyler; Young, William J.; Buckner, Spencer L.; Allen, Nic R.; Head, H. Hope

    2016-01-01

    Dolidze-35 is an under-observed northern hemisphere open cluster. It is noted in WEBDA as "No data available for this cluster". As such, we chose this cluster as an undergraduate class project to investigate its existence. We present SDSS-ugriz magnitudes for the possible cluster and cross these with existing JHK data obtained from 2MASS. Selection of possible members is aided by the proper motion study of Krone-Martins (2010).

  19. An algorithm for spatial heirarchy clustering

    NASA Technical Reports Server (NTRS)

    Dejesusparada, N. (Principal Investigator); Velasco, F. R. D.

    1981-01-01

    A method for utilizing both spectral and spatial redundancy in compacting and preclassifying images is presented. In multispectral satellite images, a high correlation exists between neighboring image points which tend to occupy dense and restricted regions of the feature space. The image is divided into windows of the same size where the clustering is made. The classes obtained in several neighboring windows are clustered, and then again successively clustered until only one region corresponding to the whole image is obtained. By employing this algorithm only a few points are considered in each clustering, thus reducing computational effort. The method is illustrated as applied to LANDSAT images.

  20. Improved regional-scale Brazilian cropping systems' mapping based on a semi-automatic object-based clustering approach

    NASA Astrophysics Data System (ADS)

    Bellón, Beatriz; Bégué, Agnès; Lo Seen, Danny; Lebourgeois, Valentine; Evangelista, Balbino Antônio; Simões, Margareth; Demonte Ferraz, Rodrigo Peçanha

    2018-06-01

    Cropping systems' maps at fine scale over large areas provide key information for further agricultural production and environmental impact assessments, and thus represent a valuable tool for effective land-use planning. There is, therefore, a growing interest in mapping cropping systems in an operational manner over large areas, and remote sensing approaches based on vegetation index time series analysis have proven to be an efficient tool. However, supervised pixel-based approaches are commonly adopted, requiring resource consuming field campaigns to gather training data. In this paper, we present a new object-based unsupervised classification approach tested on an annual MODIS 16-day composite Normalized Difference Vegetation Index time series and a Landsat 8 mosaic of the State of Tocantins, Brazil, for the 2014-2015 growing season. Two variants of the approach are compared: an hyperclustering approach, and a landscape-clustering approach involving a previous stratification of the study area into landscape units on which the clustering is then performed. The main cropping systems of Tocantins, characterized by the crop types and cropping patterns, were efficiently mapped with the landscape-clustering approach. Results show that stratification prior to clustering significantly improves the classification accuracies for underrepresented and sparsely distributed cropping systems. This study illustrates the potential of unsupervised classification for large area cropping systems' mapping and contributes to the development of generic tools for supporting large-scale agricultural monitoring across regions.

  1. Low-amplitude clustering in low-redshift 21-cm intensity maps cross-correlated with 2dF galaxy densities

    NASA Astrophysics Data System (ADS)

    Anderson, C. J.; Luciw, N. J.; Li, Y.-C.; Kuo, C. Y.; Yadav, J.; Masui, K. W.; Chang, T.-C.; Chen, X.; Oppermann, N.; Liao, Y.-W.; Pen, U.-L.; Price, D. C.; Staveley-Smith, L.; Switzer, E. R.; Timbie, P. T.; Wolz, L.

    2018-05-01

    We report results from 21-cm intensity maps acquired from the Parkes radio telescope and cross-correlated with galaxy maps from the 2dF galaxy survey. The data span the redshift range 0.057 < z < 0.098 and cover approximately 1300 deg2 over two long fields. Cross-correlation is detected at a significance of 5.7 σ. The amplitude of the cross-power spectrum is low relative to the expected dark matter power spectrum, assuming a neutral hydrogen (H I) bias and mass density equal to measurements from the ALFALFA survey. The decrement is pronounced and statistically significant at small scales. At k ˜ 1.5 h Mpc-1, the cross-power spectrum is more than a factor of 6 lower than expected, with a significance of 15.3 σ. This decrement indicates a lack of clustering of neutral hydrogen (H I), a small correlation coefficient between optical galaxies and H I, or some combination of the two. Separating 2dF into red and blue galaxies, we find that red galaxies are much more weakly correlated with H I on k ˜ 1.5 h Mpc-1 scales, suggesting that H I is more associated with blue star-forming galaxies and tends to avoid red galaxies.

  2. Cluster Observations of Non-Time Continuous Magnetosonic Waves

    NASA Technical Reports Server (NTRS)

    Walker, Simon N.; Demekhov, Andrei G.; Boardsen, Scott A.; Ganushkina, Natalia Y.; Sibeck, David G.; Balikhin, Michael A.

    2016-01-01

    Equatorial magnetosonic waves are normally observed as temporally continuous sets of emissions lasting from minutes to hours. Recent observations, however, have shown that this is not always the case. Using Cluster data, this study identifies two distinct forms of these non temporally continuous use missions. The first, referred to as rising tone emissions, are characterized by the systematic onset of wave activity at increasing proton gyroharmonic frequencies. Sets of harmonic emissions (emission elements)are observed to occur periodically in the region +/- 10 off the geomagnetic equator. The sweep rate of these emissions maximizes at the geomagnetic equator. In addition, the ellipticity and propagation direction also change systematically as Cluster crosses the geomagnetic equator. It is shown that the observed frequency sweep rate is unlikely to result from the sideband instability related to nonlinear trapping of suprathermal protons in the wave field. The second form of emissions is characterized by the simultaneous onset of activity across a range of harmonic frequencies. These waves are observed at irregular intervals. Their occurrence correlates with changes in the spacecraft potential, a measurement that is used as a proxy for electron density. Thus, these waves appear to be trapped within regions of localized enhancement of the electron density.

  3. Vacuum ultraviolet imagery of the Virgo cluster region

    NASA Astrophysics Data System (ADS)

    Onaka, T.; Tanaka, W.; Watanabe, T.; Watanabe, J.; Yamaguchi, A.; Nakagiri, M.; Kodaira, K.; Nakano, M.; Sasaki, M.; Tsujimura, T.; Yamashita, K.

    1989-07-01

    The results are reported of an experiment using the UV imager aboard an attitude-controlled S520 type sounding rocket. The total UV fluxes of galaxies in the Virgo Cluster as well as the flux level of the diffuse UV background around the cluster were measured. The data on NGC 4486 and NGC 4472 confirm the variation in the degree of the 'turnup' below 200 nm in the energy spectrum of the total light of elliptical galaxies. At two-color diagram of galaxies of visual/near-UV/vacuum UV indicates that colors of spiral galaxies are distributed within a strip and well-correlated with the morphological type, while elliptical galaxies are located differently from spiral galaxies.

  4. Young star clusters in the circumnuclear region of NGC 2110

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Durré, Mark; Mould, Jeremy, E-mail: mdurre@swin.edu.au

    2014-03-20

    High-resolution observations in the near infrared show star clusters around the active galactic nucleus (AGN) of the Seyfert 1 NGC 2110, along with a 90 × 35 pc bar of shocked gas material around its nucleus. These are seen for the first time in our imaging and gas kinematics of the central 100 pc with the Keck OSIRIS instrument with adaptive optics. Each of these clusters is two to three times brighter than the Arches cluster close to the center of the Milky Way. The core star formation rate is 0.3 M {sub ☉} yr{sup –1}. The photoionized gas (Hemore » I) dynamics imply an enclosed mass of 3-4 × 10{sup 8} M {sub ☉}. These observations demonstrate the physical linkage between AGN feedback, which triggers star formation in massive clusters, and the resulting stellar (and supernovae) winds, which cause the observed [Fe II] emission and feed the black hole.« less

  5. ISW-galaxy cross correlation: a probe of dark energy clustering and distribution of dark matter tracers

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Khosravi, Shahram; Mollazadeh, Amir; Baghram, Shant, E-mail: khosravi_sh@khu.ac.ir, E-mail: amirmollazadeh@khu.ac.ir, E-mail: baghram@sharif.edu

    2016-09-01

    Cross correlation of the Integrated Sachs-Wolfe signal (ISW) with the galaxy distribution in late time is a promising tool for constraining the dark energy properties. Here, we study the effect of dark energy clustering on the ISW-galaxy cross correlation and demonstrate the fact that the bias parameter between the distribution of the galaxies and the underlying dark matter introduces a degeneracy and complications. We argue that as the galaxy's host halo formation time is different from the observation time, we have to consider the evolution of the halo bias parameter. It will be shown that any deviation from ΛCDM modelmore » will change the evolution of the bias as well. Therefore, it is deduced that the halo bias depends strongly on the sub-sample of galaxies which is chosen for cross correlation and that the joint kernel of ISW effect and the galaxy distribution has a dominant effect on the observed signal. In this work, comparison is made specifically between the clustered dark energy models using two samples of galaxies. The first one is a sub-sample of galaxies from Sloan Digital Sky Survey, chosen with the r-band magnitude 18 < r < 21 and the dark matter halo host of mass M ∼10{sup 12} M {sub ⊙} and formation redshift of z {sub f} ∼ 2.5. The second one is the sub-sample of Luminous Red galaxies with the dark matter halo hosts of mass M ∼ 10{sup 13} M {sub ⊙} and formation redshift of z {sub f} ∼ 2.0. Using the evolved bias we improve the χ{sup 2} for the ΛCDM which reconciles the ∼1σ-2σ tension of the ISW-galaxy signal with ΛCDM prediction. Finally, we study the parameter estimation of a dark energy model with free parameters w {sub 0} and w {sub a} in the equation of state w {sub de} = w {sub 0} + w {sub az} /(1+ z ) with the constant bias parameter and also with an evolved bias model with free parameters of galaxy's host halo mass and the halo formation redshift.« less

  6. The Size Distribution Of Cluster Galaxies

    NASA Astrophysics Data System (ADS)

    Kuchner, U.; Ziegler, B.; Bamford, S.; Verdugo, M.; Haeussler, B.

    2017-06-01

    We establish a sample of 560 spectroscopically confirmed cluster members of MACS J1206.2- 0847 at z = 0.45 and utilize multi-wavelength and multi-component Sersic profile fitting to provide luminosities and sizes for the key structural components bulge and disk. While the difference between field and cluster galaxy properties are mostly due to a preference for cluster members to be early-type (quiescent, bulge-dominated), we see evidence for an outer disk fading and a sharp rise in the number of red disks with smaller effective radii at the tidally active cluster region around R200. Even though red disks are already virialized according to their velocity distribution, they are clearly not part of the old population found in the innermost region; they represent an important population of transitional objects in clusters.

  7. Regional Centre of Expertise (RCE) Rhine-Meuse: A Cross-Border Network

    ERIC Educational Resources Information Center

    Rikers, Jos H. A. N.; Hermans, Jos H. C. L. M.

    2008-01-01

    Purpose: The purpose of this paper is to introduce the case of the cross-border RCE Rhine-Meuse established as the first Regional Centre of Expertise (RCE) on Education for Sustainable Development in Europe. RCE Rhine-Meuse is an initiative of two institutions of higher education in the South of The Netherlands, but reaching out to the German and…

  8. Cluster size resolving analysis of CH3F-(ortho-H2)n in solid para-hydrogen using FTIR absorption spectroscopy at 3 μm region.

    PubMed

    Miyamoto, Yuki; Momose, Takamasa; Kanamori, Hideto

    2012-11-21

    Infrared absorption spectra of methyl fluoride with ortho-hydrogen (ortho-H(2)) clusters in a solid para-hydrogen (para-H(2)) crystal at 3.6 K were studied in the C-H stretching fundamental region (~3000 cm(-1)) using an FTIR spectrometer. As shown previously, the ν(3) C-F stretching fundamental band of CH(3)F-(ortho-H(2))(n) (n = 0, 1, 2, ...) clusters at 1040 cm(-1) shows a series of n discrete absorption lines, which correspond to different-sized clusters. We observed three unresolved broad peaks in the C-H stretching region and applied this cluster model to them assuming the same intensity distribution function as the ν(3) band. A fitting analysis successfully gave us the linewidth and lineshift of the components in each vibrational band. It was found that the separately determined linewidth, matrix shift of the band origin, and cluster shift are dependent on the vibrational mode. From the transition intensities of the monomer component derived from the fitting analysis, we discuss the mixing ratio of the vibrational modes due to Fermi resonance.

  9. Manipulation of Microbubble Clusters Using Focused Ultrasound

    NASA Astrophysics Data System (ADS)

    Matsuzaki, Hironobu; Osaki, Taichi; Kawaguchi, Kei; Unga, Johan; Ichiyanagi, Mitsuhisa; Azuma, Takashi; Suzuki, Ryo; Maruyama, Kazuo; Takagi, Shu

    2017-11-01

    In recent years, microbubbles (MBs) are expected to be utilized for the ultrasound drug delivery system (DDS). For the MB-DDS, it is important to establish a method of controlling bubbles and bubble clusters using ultrasound field. The objective of this study is to clarify behaviors of bubble clusters with various physical conditions. MBs in the ultrasound field are subjected to the primary Bjerknes force. The force traps MBs at the focal region of the focused ultrasound field. The trapped MBs form a bubble cluster at the region. A bubble cluster continues growing with absorbing surrounding bubbles until it reaches a maximum size beyond which it disappears from the focal region. In the present study, two kinds of MBs are used for the experiment. One is Sonazoid with average diameter of 2.6 um and resonant frequency of 5 MHz. The other is developed by Teikyo Univ., with average diameter of 1.5 um and presumed resonant frequency of 4 MHz. The bubble cluster's behaviors are analyzed using the high-speed camera. Sonazoid clusters have larger critical size than the other in every frequency, and its cluster size is inversely proportional to the ultrasound frequency, while Teikyo-bubble clusters have different tendency. These results are discussed in the presentation.

  10. The polar cusp: Cluster observations and simulations

    NASA Astrophysics Data System (ADS)

    Escoubet, C. Philippe; Berchem, Jean; Pitout, Frederic; Richard, Robert; Trattner, Karlheinz; Grison, Benjamin; Taylor, Matthew; Laakso, Harri; Masson, Arnaud; Dunlop, Malcolm; Dandouras, Iannis; Reme, Henri; Fazakerley, Andrew N.

    The polar cusp, together with the magnetopause, are the magnetospheric regions in direct contact with the shocked solar wind flowing continuously from the Sun. Therefore any changes in the solar wind plasma reaching the magnetopause induce changes in the polar cusp with a delay of a few minutes to a few tens of minutes. For instance a change of the interplanetary magnetic field (IMF) direction from South to North will displace the polar cusp poleward and at the same time will change the injection of ions from the subsolar magnetopause to the magnetotail lobes. In the mid and low-altitude cusp a spacecraft will then observe a reversal of the dispersion in energy of the ions. We will use Cluster string of pearl configuration in the mid-altitude polar cusp to investigate the temporal variations of ion injections in the polar cusp. In the period from July to September, the Cluster spacecraft follow each other in the mid-altitude cusp with a delay of few minutes up to one hour. A few examples of cusp crossings will be presented to illustrate the influence of solar wind changes in the polar cusp. We will show that a sudden change in the IMF direction from South to North produces a double cusp crossing. By opposition, a change of the IMF from North to South produces a temporal injection on the equatorward side of the cusp and an erosion of the magnetosphere. Finally, we will show that when the interplanetary conditions are stable with the IMF pointing Northward or Southward for more than 10 min the polar cusp ion dispersion stays constant. MHD and large-scale particle simulations will also be used to complement the Cluster data.

  11. Long-range looping of a locus control region drives tissue-specific chromatin packing within a multigene cluster

    PubMed Central

    Tsai, Yu-Cheng; Cooke, Nancy E.; Liebhaber, Stephen A.

    2016-01-01

    Abstract The relationships of higher order chromatin organization to mammalian gene expression remain incompletely defined. The human Growth Hormone (hGH) multigene cluster contains five gene paralogs. These genes are selectively activated in either the pituitary or the placenta by distinct components of a remote locus control region (LCR). Prior studies have revealed that appropriate activation of the placental genes is dependent not only on the actions of the LCR, but also on the multigene composition of the cluster itself. Here, we demonstrate that the hGH LCR ‘loops’ over a distance of 28 kb in primary placental nuclei to make specific contacts with the promoters of the two GH genes in the cluster. This long-range interaction sequesters the GH genes from the three hCS genes which co-assemble into a tightly packed ‘hCS chromatin hub’. Elimination of the long-range looping, via specific deletion of the placental LCR components, triggers a dramatic disruption of the hCS chromatin hub. These data reveal a higher-order structural pathway by which long-range looping from an LCR impacts on local chromatin architecture that is linked to tissue-specific gene regulation within a multigene cluster. PMID:26893355

  12. Constraints on the interaction between dark matter and Baryons from cooling flow clusters.

    PubMed

    Qin, B; Wu, X P

    2001-08-06

    Other nongravitational heating processes are needed to resolve the disagreement between the absence of cool gas components in the centers of galaxy clusters revealed recently by Chandra and XMM observations and the expectations of conventional radiative cooling models. We propose that the interaction between dark matter and baryonic matter may act as an alternative for the reheating of intracluster medium (ICM) in the inner regions of clusters, in which kinetic energy of dark matter is transported to ICM to balance radiative cooling. Using the Chandra and XMM data, we set a useful constraint on the dark-matter-baryon cross section: sigma(xp)/m(x) approximately 1x10(-25) cm(2) GeV-1, where m(x) is the mass of dark matter particles.

  13. Cluster fusion-fission dynamics in the Singapore stock exchange

    NASA Astrophysics Data System (ADS)

    Teh, Boon Kin; Cheong, Siew Ann

    2015-10-01

    In this paper, we investigate how the cross-correlations between stocks in the Singapore stock exchange (SGX) evolve over 2008 and 2009 within overlapping one-month time windows. In particular, we examine how these cross-correlations change before, during, and after the Sep-Oct 2008 Lehman Brothers Crisis. To do this, we extend the complete-linkage hierarchical clustering algorithm, to obtain robust clusters of stocks with stronger intracluster correlations, and weaker intercluster correlations. After we identify the robust clusters in all time windows, we visualize how these change in the form of a fusion-fission diagram. Such a diagram depicts graphically how the cluster sizes evolve, the exchange of stocks between clusters, as well as how strongly the clusters mix. From the fusion-fission diagram, we see a giant cluster growing and disintegrating in the SGX, up till the Lehman Brothers Crisis in September 2008 and the market crashes of October 2008. After the Lehman Brothers Crisis, clusters in the SGX remain small for few months before giant clusters emerge once again. In the aftermath of the crisis, we also find strong mixing of component stocks between clusters. As a result, the correlation between initially strongly-correlated pairs of stocks decay exponentially with average life time of about a month. These observations impact strongly how portfolios and trading strategies should be formulated.

  14. Observations of EMIC Waves in the Exterior Cusp Region and in the Nearby Magnetosheath

    NASA Astrophysics Data System (ADS)

    Grison, B.; Escoubet, C. P.; Santolik, O.; Lavraud, B.; Cornilleau-Wehrlin, N.

    2014-12-01

    In the early years (2000-2004) of the mission, Cluster crossed the most distant part of the polar cusps. On 05/01/2002, Cluster enters the distant cusp region on the duskside of the southern hemisphere (inbound). The spacecraft are successively crossing the magnetopause between 19:50 UT (SC4) and 20:15 UT (SC3). The interplanetary conditions during the crossing were stable with a dominant negative By. The magnetometer (FGM) data indicates that the entry into the cusp takes place in a region where the magnetic field lines in the magnetosheath are anti-parallel with the field lines in the magnetosphere. Despite this clear picture, the global encounter is rather complex: one can notice partial magnetopause crossings, magnetic null points, and intense monochromatic waves on both sides of the magnetopause.We investigate electromagnetic ion cyclotron (EMIC) waves observed in the cusp and in the nearby magnetosheath, just before the magnetopause crossing by the spacecraft. Left-handed monochromatic waves observed in the cusp display different duration and frequency (below and above the local proton gyrofrequency) on each spacecraft. Both the Poynting flux of these emissions and the simultaneously recorded ion flows propagate in the same direction - toward the Earth. The wavenumber are determined in two ways: considering the Doppler shift and from direct measurements of the refractive index. We analyze these wave parameters and the local plasma conditions to explain the wave generation process on each side of the magnetopause.

  15. Cross-modal activation of auditory regions during visuo-spatial working memory in early deafness.

    PubMed

    Ding, Hao; Qin, Wen; Liang, Meng; Ming, Dong; Wan, Baikun; Li, Qiang; Yu, Chunshui

    2015-09-01

    Early deafness can reshape deprived auditory regions to enable the processing of signals from the remaining intact sensory modalities. Cross-modal activation has been observed in auditory regions during non-auditory tasks in early deaf subjects. In hearing subjects, visual working memory can evoke activation of the visual cortex, which further contributes to behavioural performance. In early deaf subjects, however, whether and how auditory regions participate in visual working memory remains unclear. We hypothesized that auditory regions may be involved in visual working memory processing and activation of auditory regions may contribute to the superior behavioural performance of early deaf subjects. In this study, 41 early deaf subjects (22 females and 19 males, age range: 20-26 years, age of onset of deafness < 2 years) and 40 age- and gender-matched hearing controls underwent functional magnetic resonance imaging during a visuo-spatial delayed recognition task that consisted of encoding, maintenance and recognition stages. The early deaf subjects exhibited faster reaction times on the spatial working memory task than did the hearing controls. Compared with hearing controls, deaf subjects exhibited increased activation in the superior temporal gyrus bilaterally during the recognition stage. This increased activation amplitude predicted faster and more accurate working memory performance in deaf subjects. Deaf subjects also had increased activation in the superior temporal gyrus bilaterally during the maintenance stage and in the right superior temporal gyrus during the encoding stage. These increased activation amplitude also predicted faster reaction times on the spatial working memory task in deaf subjects. These findings suggest that cross-modal plasticity occurs in auditory association areas in early deaf subjects. These areas are involved in visuo-spatial working memory. Furthermore, amplitudes of cross-modal activation during the maintenance stage were

  16. Cluster redshifts in five suspected superclusters

    NASA Technical Reports Server (NTRS)

    Ciardullo, R.; Ford, H.; Harms, R.

    1985-01-01

    Redshift surveys for rich superclusters were carried out in five regions of the sky containing surface-density enhancements of Abell clusters. While several superclusters are identified, projection effects dominate each field, and no system contains more than five rich clusters. Two systems are found to be especially interesting. The first, field 0136 10, is shown to contain a superposition of at least four distinct superclusters, with the richest system possessing a small velocity dispersion. The second system, 2206 - 22, though a region of exceedingly high Abell cluster surface density, appears to be a remarkable superposition of 23 rich clusters almost uniformly distributed in redshift space between 0.08 and 0.24. The new redshifts significantly increase the three-dimensional information available for the distance class 5 and 6 Abell clusters and allow the spatial correlation function around rich superclusters to be estimated.

  17. HUBBLE PINPOINTS WHITE DWARFS IN GLOBULAR CLUSTER

    NASA Technical Reports Server (NTRS)

    2002-01-01

    Peering deep inside a cluster of several hundred thousand stars, NASA's Hubble Space Telescope uncovered the oldest burned-out stars in our Milky Way Galaxy. Located in the globular cluster M4, these small, dying stars - called white dwarfs - are giving astronomers a fresh reading on one of the biggest questions in astronomy: How old is the universe? The ancient white dwarfs in M4 are about 12 to 13 billion years old. After accounting for the time it took the cluster to form after the big bang, astronomers found that the age of the white dwarfs agrees with previous estimates for the universe's age. In the top panel, a ground-based observatory snapped a panoramic view of the entire cluster, which contains several hundred thousand stars within a volume of 10 to 30 light-years across. The Kitt Peak National Observatory's 0.9-meter telescope took this picture in March 1995. The box at left indicates the region observed by the Hubble telescope. The Hubble telescope studied a small region of the cluster. A section of that region is seen in the picture at bottom left. A sampling of an even smaller region is shown at bottom right. This region is only about one light-year across. In this smaller region, Hubble pinpointed a number of faint white dwarfs. The blue circles pinpoint the dwarfs. It took nearly eight days of exposure time over a 67-day period to find these extremely faint stars. Globular clusters are among the oldest clusters of stars in the universe. The faintest and coolest white dwarfs within globular clusters can yield a globular cluster's age. Earlier Hubble observations showed that the first stars formed less than 1 billion years after the universe's birth in the big bang. So, finding the oldest stars puts astronomers within arm's reach of the universe's age. M4 is 7,000 light-years away in the constellation Scorpius. Hubble's Wide Field and Planetary Camera 2 made the observations from January through April 2001. These optical observations were combined to

  18. Cosmological Simulations of Galaxy Clusters

    NASA Astrophysics Data System (ADS)

    Borgani, Stefano; Kravtsov, Andrey

    2011-02-01

    We review recent progress in the description of the formation and evolution of galaxy clusters in a cosmological context by using state-of-art numerical simulations. We focus our presentation on the comparison between simulated and observed X-ray properties, while we will also discuss numerical predictions on properties of the galaxy population in clusters, as observed in the optical band. Many of the salient observed properties of clusters, such as scaling relations between X-ray observables and total mass, radial profiles of entropy and density of the intracluster gas, and radial distribution of galaxies are reproduced quite well. In particular, the outer regions of cluster at radii beyond about 10 per cent of the virial radius are quite regular and exhibit scaling with mass remarkably close to that expected in the simplest case in which only the action of gravity determines the evolution of the intra-cluster gas. However, simulations generally fail at reproducing the observed "cool core" structure of clusters: simulated clusters generally exhibit a significant excess of gas cooling in their central regions, which causes both an overestimate of the star formation in the cluster centers and incorrect temperature and entropy profiles. The total baryon fraction in clusters is below the mean universal value, by an amount which depends on the cluster-centric distance and the physics included in the simulations, with interesting tensions between observed stellar and gas fractions in clusters and predictions of simulations. Besides their important implications for the cosmological application of clusters, these puzzles also point towards the important role played by additional physical processes, beyond those already included in the simulations. We review the role played by these processes, along with the difficulty for their implementation, and discuss the outlook for the future progress in numerical modeling of clusters.

  19. m-BIRCH: an online clustering approach for computer vision applications

    NASA Astrophysics Data System (ADS)

    Madan, Siddharth K.; Dana, Kristin J.

    2015-03-01

    We adapt a classic online clustering algorithm called Balanced Iterative Reducing and Clustering using Hierarchies (BIRCH), to incrementally cluster large datasets of features commonly used in multimedia and computer vision. We call the adapted version modified-BIRCH (m-BIRCH). The algorithm uses only a fraction of the dataset memory to perform clustering, and updates the clustering decisions when new data comes in. Modifications made in m-BIRCH enable data driven parameter selection and effectively handle varying density regions in the feature space. Data driven parameter selection automatically controls the level of coarseness of the data summarization. Effective handling of varying density regions is necessary to well represent the different density regions in data summarization. We use m-BIRCH to cluster 840K color SIFT descriptors, and 60K outlier corrupted grayscale patches. We use the algorithm to cluster datasets consisting of challenging non-convex clustering patterns. Our implementation of the algorithm provides an useful clustering tool and is made publicly available.

  20. Symptom clusters and quality of life among patients with advanced heart failure

    PubMed Central

    Yu, Doris SF; Chan, Helen YL; Leung, Doris YP; Hui, Elsie; Sit, Janet WH

    2016-01-01

    Objectives To identify symptom clusters among patients with advanced heart failure (HF) and the independent relationships with their quality of life (QoL). Methods This is the secondary data analysis of a cross-sectional study which interviewed 119 patients with advanced HF in the geriatric unit of a regional hospital in Hong Kong. The symptom profile and QoL were assessed by using the Edmonton Symptom Assessment Scale (ESAS) and the McGill QoL Questionnaire. Exploratory factor analysis was used to identify the symptom clusters. Hierarchical regression analysis was used to examine the independent relationships with their QoL, after adjusting the effects of age, gender, and comorbidities. Results The patients were at an advanced age (82.9 ± 6.5 years). Three distinct symptom clusters were identified: they were the distress cluster (including shortness of breath, anxiety, and depression), the decondition cluster (fatigue, drowsiness, nausea, and reduced appetite), and the discomfort cluster (pain, and sense of generalized discomfort). These three symptom clusters accounted for 63.25% of variance of the patients' symptom experience. The small to moderate correlations between these symptom clusters indicated that they were rather independent of one another. After adjusting the age, gender and comorbidities, the distress (β = −0.635, P < 0.001), the decondition (β = −0.148, P = 0.01), and the discomfort (β = −0.258, P < 0.001) symptom clusters independently predicted their QoL. Conclusions This study identified the distinctive symptom clusters among patients with advanced HF. The results shed light on the need to develop palliative care interventions for optimizing the symptom control for this life-limiting disease. PMID:27403150

  1. Governance and Regional Variation of Homicide Rates: Evidence From Cross-National Data.

    PubMed

    Cao, Liqun; Zhang, Yan

    2017-01-01

    Criminological theories of cross-national studies of homicide have underestimated the effects of quality governance of liberal democracy and region. Data sets from several sources are combined and a comprehensive model of homicide is proposed. Results of the spatial regression model, which controls for the effect of spatial autocorrelation, show that quality governance, human development, economic inequality, and ethnic heterogeneity are statistically significant in predicting homicide. In addition, regions of Latin America and non-Muslim Sub-Saharan Africa have significantly higher rates of homicides ceteris paribus while the effects of East Asian countries and Islamic societies are not statistically significant. These findings are consistent with the expectation of the new modernization and regional theories. © The Author(s) 2015.

  2. The HectoMAP Cluster Survey. I. redMaPPer Clusters

    NASA Astrophysics Data System (ADS)

    Sohn, Jubee; Geller, Margaret J.; Rines, Kenneth J.; Hwang, Ho Seong; Utsumi, Yousuke; Diaferio, Antonaldo

    2018-04-01

    We use the dense HectoMAP redshift survey to explore the properties of 104 redMaPPer cluster candidates. The redMaPPer systems in HectoMAP cover the full range of richness and redshift (0.08 < z < 0.60). Fifteen of the systems included in the Subaru/Hyper Suprime-Cam public data release are bona fide clusters. The median number of spectroscopic members per cluster is ∼20. We include redshifts of 3547 member candidates listed in the redMaPPer catalog whether they are cluster members or not. We evaluate the redMaPPer membership probability spectroscopically. The purity (number of real systems) in redMaPPer exceeds 90% even at the lowest richness. Three massive galaxy clusters (M ∼ 2 × 1013 M ⊙) associated with X-ray emission in the HectoMAP region are not included in the public redMaPPer catalog with λ rich > 20, because they lie outside the cuts for this catalog.

  3. The HectoMAP Cluster Survey. I. redMaPPer Clusters

    DOE PAGES

    Sohn, Jubee; Geller, Margaret J.; Rines, Kenneth J.; ...

    2018-04-05

    We use the dense HectoMAP redshift survey to explore the properties of 104 redMaPPer cluster candidates. The redMaPPer systems in HectoMAP cover the full range of richness and redshift (0.08 < z < 0.60). Fifteen of the systems included in the Subaru/Hyper Suprime-Cam public data release are bona fide clusters. The median number of spectroscopic members per cluster is ~20. We include redshifts of 3547 member candidates listed in the redMaPPer catalog whether they are cluster members or not. Here, we evaluate the redMaPPer membership probability spectroscopically. The purity (number of real systems) in redMaPPer exceeds 90% even at themore » lowest richness. Three massive galaxy clusters (M ~ 2 × 10 13 M ⊙) associated with X-ray emission in the HectoMAP region are not included in the public redMaPPer catalog with λ rich > 20, because they lie outside the cuts for this catalog.« less

  4. The HectoMAP Cluster Survey. I. redMaPPer Clusters

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sohn, Jubee; Geller, Margaret J.; Rines, Kenneth J.

    We use the dense HectoMAP redshift survey to explore the properties of 104 redMaPPer cluster candidates. The redMaPPer systems in HectoMAP cover the full range of richness and redshift (0.08 < z < 0.60). Fifteen of the systems included in the Subaru/Hyper Suprime-Cam public data release are bona fide clusters. The median number of spectroscopic members per cluster is ~20. We include redshifts of 3547 member candidates listed in the redMaPPer catalog whether they are cluster members or not. Here, we evaluate the redMaPPer membership probability spectroscopically. The purity (number of real systems) in redMaPPer exceeds 90% even at themore » lowest richness. Three massive galaxy clusters (M ~ 2 × 10 13 M ⊙) associated with X-ray emission in the HectoMAP region are not included in the public redMaPPer catalog with λ rich > 20, because they lie outside the cuts for this catalog.« less

  5. Distant Galaxy Clusters Hosting Extreme Central Galaxies

    NASA Astrophysics Data System (ADS)

    McDonald, Michael

    2014-09-01

    The recently-discovered Phoenix cluster harbors the most star-forming central cluster galaxy of any cluster in the known Universe, by nearly a factor of 10. This extreme system appears to be fulfilling early cooling flow predictions, although the lack of similar systems makes any interpretation difficult. In an attempt to find other "Phoenix-like" clusters, we have cross-correlated archival all-sky surveys (in which Phoenix was detected) and isolated 4 similarly-extreme systems which are also coincident in position and redshift with an overdensity of red galaxies. We propose here to obtain Chandra observations of these extreme, Phoenix-like systems, in order to confirm them as relaxed, rapidly-cooling galaxy clusters.

  6. Creating multithemed ecological regions for macroscale ecology: Testing a flexible, repeatable, and accessible clustering method

    USGS Publications Warehouse

    Cheruvelil, Kendra Spence; Yuan, Shuai; Webster, Katherine E.; Tan, Pang-Ning; Lapierre, Jean-Francois; Collins, Sarah M.; Fergus, C. Emi; Scott, Caren E.; Norton Henry, Emily; Soranno, Patricia A.; Filstrup, Christopher T.; Wagner, Tyler

    2017-01-01

    Understanding broad-scale ecological patterns and processes often involves accounting for regional-scale heterogeneity. A common way to do so is to include ecological regions in sampling schemes and empirical models. However, most existing ecological regions were developed for specific purposes, using a limited set of geospatial features and irreproducible methods. Our study purpose was to: (1) describe a method that takes advantage of recent computational advances and increased availability of regional and global data sets to create customizable and reproducible ecological regions, (2) make this algorithm available for use and modification by others studying different ecosystems, variables of interest, study extents, and macroscale ecology research questions, and (3) demonstrate the power of this approach for the research question—How well do these regions capture regional-scale variation in lake water quality? To achieve our purpose we: (1) used a spatially constrained spectral clustering algorithm that balances geospatial homogeneity and region contiguity to create ecological regions using multiple terrestrial, climatic, and freshwater geospatial data for 17 northeastern U.S. states (~1,800,000 km2); (2) identified which of the 52 geospatial features were most influential in creating the resulting 100 regions; and (3) tested the ability of these ecological regions to capture regional variation in water nutrients and clarity for ~6,000 lakes. We found that: (1) a combination of terrestrial, climatic, and freshwater geospatial features influenced region creation, suggesting that the oft-ignored freshwater landscape provides novel information on landscape variability not captured by traditionally used climate and terrestrial metrics; and (2) the delineated regions captured macroscale heterogeneity in ecosystem properties not included in region delineation—approximately 40% of the variation in total phosphorus and water clarity among lakes was at the regional

  7. Primordial binary populations in low-density star clusters as seen by Chandra: globular clusters versus old open clusters

    NASA Astrophysics Data System (ADS)

    van den Berg, Maureen C.

    2015-08-01

    The binaries in the core of a star cluster are the energy source that prevents the cluster from experiencing core collapse. To model the dynamical evolution of a cluster, it is important to have constraints on the primordial binary content. X-ray observations of old star clusters are very efficient in detecting the close interacting binaries among the cluster members. The X-ray sources in star clusters are a mix of binaries that were dynamically formed and primordial binaries. In massive, dense star clusters, dynamical encounters play an important role in shaping the properties and numbers of the binaries. In contrast, in the low-density clusters the impact of dynamical encounters is presumed to be very small, and the close binaries detected in X-rays represent a primordial population. The lowest density globular clusters have current masses and central densities similar to those of the oldest open clusters in our Milky Way. I will discuss the results of studies with the Chandra X-ray Observatory that have nevertheless revealed a clear dichotomy: far fewer (if any at all) X-ray sources are detected in the central regions of the low-density globular clusters compared to the number of secure cluster members that have been detected in old open clusters (above a limiting X-ray luminosity of typically 4e30 erg/s). The low stellar encounter rates imply that dynamical destruction of binaries can be ignored at present, therefore an explanation must be sought elsewhere. I will discuss several factors that can shed light on the implied differences between the primordial close binary populations in the two types of star clusters.

  8. Multi-spacecraft studies of the auroral acceleration region: From cluster to nanosatellites

    NASA Astrophysics Data System (ADS)

    Sadeghi, S.; Emami, M. R.

    2017-03-01

    This paper discusses the utilization of multiple Cubesats in various formations for studies in the auroral acceleration region. The focus is on the quasi-static properties, spatio-temporal features, electric potential structures, field-aligned currents, and their relationships, all of which are fundamentally important for an understanding of the magnetosphere-ionosphere coupling. It is argued that a multitude of nanosatellites can address some of the relevant outstanding questions in a broader range of spatial, temporal, and geometrical features, with higher redundancy and data consistency, potentially resulting in a shorter mission period and a higher chance of mission success. A number of mission concepts consisting of a cluster of 6-12 Cubesats with their specific onboard payloads are suggested for such missions over a period of as short as two months.

  9. Massive Star Clusters in Ongoing Galaxy Interactions: Clues to Cluster Formation

    NASA Astrophysics Data System (ADS)

    Keel, William C.; Borne, Kirk D.

    2003-09-01

    We present HST WFPC2 observations, supplemented by ground-based Hα data, of the star-cluster populations in two pairs of interacting galaxies selected for being in very different kinds of encounters seen at different stages. Dynamical information and n-body simulations provide the details of encounter geometry, mass ratio, and timing. In NGC 5752/4 we are seeing a weak encounter, well past closest approach, after about 2.5×108 yr. The large spiral NGC 5754 has a normal population of disk clusters, while the fainter companion NGC 5752 exhibits a rich population of luminous clusters with a flatter luminosity function. The strong, ongoing encounter in NGC 6621/2, seen about 1.0×108 yr past closest approach between roughly equal-mass galaxies, has produced an extensive population of luminous clusters, particularly young and luminous in a small region between the two nuclei. This region is dynamically interesting, with such a strong perturbation in the velocity field that the rotation curve reverses sign. From these results, in comparison with other strongly interacting systems discussed in the literature, cluster formation requires a threshold level of perturbation, with stage of the interaction a less important factor. The location of the most active star formation in NGC 6621/2 draws attention to a possible role for the Toomre stability threshold in shaping star formation in interacting galaxies. The rich cluster populations in NGC 5752 and NGC 6621 show that direct contact between gas-rich galaxy disks is not a requirement to form luminous clusters and that they can be triggered by processes happening within a single galaxy disk (albeit triggered by external perturbations). Based on observations with the NASA/ESA Hubble Space Telescope, obtained at the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Inc., under NASA contract NAS 5-26555.

  10. STAR CLUSTER FORMATION WITH STELLAR FEEDBACK AND LARGE-SCALE INFLOW

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Matzner, Christopher D.; Jumper, Peter H., E-mail: matzner@astro.utoronto.ca

    2015-12-10

    During star cluster formation, ongoing mass accretion is resisted by stellar feedback in the form of protostellar outflows from the low-mass stars and photo-ionization and radiation pressure feedback from the massive stars. We model the evolution of cluster-forming regions during a phase in which both accretion and feedback are present and use these models to investigate how star cluster formation might terminate. Protostellar outflows are the strongest form of feedback in low-mass regions, but these cannot stop cluster formation if matter continues to flow in. In more massive clusters, radiation pressure and photo-ionization rapidly clear the cluster-forming gas when itsmore » column density is too small. We assess the rates of dynamical mass ejection and of evaporation, while accounting for the important effect of dust opacity on photo-ionization. Our models are consistent with the census of protostellar outflows in NGC 1333 and Serpens South and with the dust temperatures observed in regions of massive star formation. Comparing observations of massive cluster-forming regions against our model parameter space, and against our expectations for accretion-driven evolution, we infer that massive-star feedback is a likely cause of gas disruption in regions with velocity dispersions less than a few kilometers per second, but that more massive and more turbulent regions are too strongly bound for stellar feedback to be disruptive.« less

  11. Embedded cluster metal-polymeric micro interface and process for producing the same

    DOEpatents

    Menezes, Marlon E.; Birnbaum, Howard K.; Robertson, Ian M.

    2002-01-29

    A micro interface between a polymeric layer and a metal layer includes isolated clusters of metal partially embedded in the polymeric layer. The exposed portion of the clusters is smaller than embedded portions, so that a cross section, taken parallel to the interface, of an exposed portion of an individual cluster is smaller than a cross section, taken parallel to the interface, of an embedded portion of the individual cluster. At least half, but not all of the height of a preferred spherical cluster is embedded. The metal layer is completed by a continuous layer of metal bonded to the exposed portions of the discontinuous clusters. The micro interface is formed by heating a polymeric layer to a temperature, near its glass transition temperature, sufficient to allow penetration of the layer by metal clusters, after isolated clusters have been deposited on the layer at lower temperatures. The layer is recooled after embedding, and a continuous metal layer is deposited upon the polymeric layer to bond with the discontinuous metal clusters.

  12. Large-scale variation in subsurface stream biofilms: a cross-regional comparison of metabolic function and community similarity.

    PubMed

    Findlay, S; Sinsabaugh, R L

    2006-10-01

    We examined bacterial metabolic activity and community similarity in shallow subsurface stream sediments distributed across three regions of the eastern United States to assess whether there were parallel changes in functional and structural attributes at this large scale. Bacterial growth, oxygen consumption, and a suite of extracellular enzyme activities were assayed to describe functional variability. Community similarity was assessed using randomly amplified polymorphic DNA (RAPD) patterns. There were significant differences in streamwater chemistry, metabolic activity, and bacterial growth among regions with, for instance, twofold higher bacterial production in streams near Baltimore, MD, compared to Hubbard Brook, NH. Five of eight extracellular enzymes showed significant differences among regions. Cluster analyses of individual streams by metabolic variables showed clear groups with significant differences in representation of sites from different regions among groups. Clustering of sites based on randomly amplified polymorphic DNA banding resulted in groups with generally less internal similarity although there were still differences in distribution of regional sites. There was a marginally significant (p = 0.09) association between patterns based on functional and structural variables. There were statistically significant but weak (r2 approximately 30%) associations between landcover and measures of both structure and function. These patterns imply a large-scale organization of biofilm communities and this structure may be imposed by factor(s) such as landcover and covariates such as nutrient concentrations, which are known to also cause differences in macrobiota of stream ecosystems.

  13. Identification of homogeneous regions for regionalization of watersheds by two-level self-organizing feature maps

    NASA Astrophysics Data System (ADS)

    Farsadnia, F.; Rostami Kamrood, M.; Moghaddam Nia, A.; Modarres, R.; Bray, M. T.; Han, D.; Sadatinejad, J.

    2014-02-01

    One of the several methods in estimating flood quantiles in ungauged or data-scarce watersheds is regional frequency analysis. Amongst the approaches to regional frequency analysis, different clustering techniques have been proposed to determine hydrologically homogeneous regions in the literature. Recently, Self-Organization feature Map (SOM), a modern hydroinformatic tool, has been applied in several studies for clustering watersheds. However, further studies are still needed with SOM on the interpretation of SOM output map for identifying hydrologically homogeneous regions. In this study, two-level SOM and three clustering methods (fuzzy c-mean, K-mean, and Ward's Agglomerative hierarchical clustering) are applied in an effort to identify hydrologically homogeneous regions in Mazandaran province watersheds in the north of Iran, and their results are compared with each other. Firstly the SOM is used to form a two-dimensional feature map. Next, the output nodes of the SOM are clustered by using unified distance matrix algorithm and three clustering methods to form regions for flood frequency analysis. The heterogeneity test indicates the four regions achieved by the two-level SOM and Ward approach after adjustments are sufficiently homogeneous. The results suggest that the combination of SOM and Ward is much better than the combination of either SOM and FCM or SOM and K-mean.

  14. α-cluster versus non-α-cluster decay of the excited compound nucleus Ce124* using the dynamical cluster-decay model

    NASA Astrophysics Data System (ADS)

    Kaur, Arshdeep; Chopra, Sahila; Gupta, Raj K.

    2014-03-01

    The dynamical cluster-decay model (DCM), an extended version of the preformed cluster model (PCM) for ground-state (T =0) decays, is applied to study the decay of the proton-rich compound nucleus Ce124* formed in the S32 + Mo92 reaction at an above-barrier beam energy of 150 MeV. Application of the statistical code pace4 to experimental data shows large deviations in all cases of proton clusters' (2p, 3p, and 4p) evaporation residue (ER) and the non-α nucleus Be6 intermediate mass fragment (IMF). Furthermore, the α-nucleus Be8 decay is not observed in this experiment (not even the upper limit is given). Using the DCM, with effects of deformations up to hexadecapole and "compact" orientations included, for the best-fitted cross sections of 2p and 3p ERs and of Li5 and Be6 IMFs, the relative cross section of Be8 is found to be more than that of Be6, possibly due to the α-nucleus structure of Be8. The same is shown to be true for C12 versus C10, i.e., α-nuclei clusters are populated strongly relative to non-α clusters, similar to what was predicted by one of us (R.K.G.) et al. [S. Kumar, D. Bir, and R. K. Gupta, Phys. Rev. C 51, 1762 (1995), 10.1103/PhysRevC.51.1762] for ground-state decays of such nuclei and the decay of Ba116* formed in the Ni58 + Ni58 reaction at various compound nucleus excitation energies [R. K. Gupta et al., J. Phys. G: Nucl. Part. Phys. 32, 345 (2006), 10.1088/0954-3899/32/3/009]. The only parameter of the DCM is the neck-length ΔR, related to the "barrier-lowering" parameter. The compound nucleus formation probability and "barrier-lowering/-modification" effects are analyzed, and the role of varying the deformations of Be6 and/or Be8 nuclei on relative cross sections is studied, since the measured deformations are not available. The ones used here are from relativistic mean-field calculations [β2(6Be )=-0.087 and β2(8Be)=-0.094]. Calculations are also presented for a beam energy of 140 MeV, supporting the above result.

  15. Constraining the mass–richness relationship of redMaPPer clusters with angular clustering

    DOE PAGES

    Baxter, Eric J.; Rozo, Eduardo; Jain, Bhuvnesh; ...

    2016-08-04

    The potential of using cluster clustering for calibrating the mass–richness relation of galaxy clusters has been recognized theoretically for over a decade. In this paper, we demonstrate the feasibility of this technique to achieve high-precision mass calibration using redMaPPer clusters in the Sloan Digital Sky Survey North Galactic Cap. By including cross-correlations between several richness bins in our analysis, we significantly improve the statistical precision of our mass constraints. The amplitude of the mass–richness relation is constrained to 7 per cent statistical precision by our analysis. However, the error budget is systematics dominated, reaching a 19 per cent total errormore » that is dominated by theoretical uncertainty in the bias–mass relation for dark matter haloes. We confirm the result from Miyatake et al. that the clustering amplitude of redMaPPer clusters depends on galaxy concentration as defined therein, and we provide additional evidence that this dependence cannot be sourced by mass dependences: some other effect must account for the observed variation in clustering amplitude with galaxy concentration. Assuming that the observed dependence of redMaPPer clustering on galaxy concentration is a form of assembly bias, we find that such effects introduce a systematic error on the amplitude of the mass–richness relation that is comparable to the error bar from statistical noise. Finally, the results presented here demonstrate the power of cluster clustering for mass calibration and cosmology provided the current theoretical systematics can be ameliorated.« less

  16. Variation in Loblolly pine cross-sectional microfibril angle with tree height and physiographic region

    Treesearch

    Lewis Jordon; Rechum Re; Daniel B. Hall; Alexander Clark; Richard F. Daniels

    2006-01-01

    The effect of height and physiographic region on whole disk cross-sectional microfibril angle (CSMFA) in loblolly pine (Pinus raeda L.) in the southern United States was evaluated. Whole disk CSMFA was determined at 1.4, 4.6, 7.6, 10.7, and 13.7 m up the stem of 59 trees, representing five physiographic regions. A mixed-effects analysis of variance was performed to...

  17. A Study of the Dependence of the Properties of Galaxy Clusters on Cluster Morphology.

    NASA Astrophysics Data System (ADS)

    Lugger, Phyllis Minnie

    1982-03-01

    A quantitative study of the properties of clusters of galaxies as a function of cluster morphology has been carried out using photographic plates obtained with the Palomar 48 inch Schmidt telescope. Surface brightness profiles of 35 first ranked cluster galaxies and luminosity functions of nine clusters are presented and analyzed. The dispersion in the metric magnitudes of first ranked galaxies is quite small ((TURN) 0.4 mag) which is consistent with the results of Kristian, Sandage and Westphal as well as Hoessel, Gunn and Thuan. For the cD (supergiant elliptical) galaxy sample, the mean metric magnitude is (TURN) 0.5 mag brighter than for the non-cD galaxies. The dispersion in the metric magnitudes for the 10 cD galaxies studied is found to be much smaller ((sigma) (TURN) 0.1 mag) than the dispersion in the metric magnitudes of the non-cD first ranked galaxies ((sigma) (TURN) 0.4 mag). The de Vaucouleurs effective radius - magnitude relation determined in the present study for first ranked galaxies (log r(,e) = -0.2 M + const.) is consistent with the extrapolations to brighter magnitudes of the range of relations found by Strom and Strom. The average residuals from the mean radius-magnitude relation for the cD and non-cD galaxy samples were not found to differ at a significant level. Luminosity functions for the region within 0.5 Mpc of the cluster center for three of the clusters studied (A1656, A2147, and A2199) show a deficit of bright galaxies when compared to a concentric annular region with bounds of 0.5 and 1.0 Mpc. Characteristic magnitudes for the nine clusters (determined from square regions 4.6 Mpc on a side) show no significant correlation with cluster morphology, central density, or total magnitude of the first ranked galaxy. The mean values of the Schechter function parameters M('*) and (alpha) are in very good agreement with the previous determinations by Schechter and by Dressler. The differential luminosity functions for A569 and A1656 do not

  18. Weak lensing magnification of SpARCS galaxy clusters

    NASA Astrophysics Data System (ADS)

    Tudorica, A.; Hildebrandt, H.; Tewes, M.; Hoekstra, H.; Morrison, C. B.; Muzzin, A.; Wilson, G.; Yee, H. K. C.; Lidman, C.; Hicks, A.; Nantais, J.; Erben, T.; van der Burg, R. F. J.; Demarco, R.

    2017-12-01

    Context. Measuring and calibrating relations between cluster observables is critical for resource-limited studies. The mass-richness relation of clusters offers an observationally inexpensive way of estimating masses. Its calibration is essential for cluster and cosmological studies, especially for high-redshift clusters. Weak gravitational lensing magnification is a promising and complementary method to shear studies, that can be applied at higher redshifts. Aims: We aim to employ the weak lensing magnification method to calibrate the mass-richness relation up to a redshift of 1.4. We used the Spitzer Adaptation of the Red-Sequence Cluster Survey (SpARCS) galaxy cluster candidates (0.2 < z < 1.4) and optical data from the Canada France Hawaii Telescope (CFHT) to test whether magnification can be effectively used to constrain the mass of high-redshift clusters. Methods: Lyman-break galaxies (LBGs) selected using the u-band dropout technique and their colours were used as a background sample of sources. LBG positions were cross-correlated with the centres of the sample of SpARCS clusters to estimate the magnification signal, which was optimally-weighted using an externally-calibrated LBG luminosity function. The signal was measured for cluster sub-samples, binned in both redshift and richness. Results: We measured the cross-correlation between the positions of galaxy cluster candidates and LBGs and detected a weak lensing magnification signal for all bins at a detection significance of 2.6-5.5σ. In particular, the significance of the measurement for clusters with z> 1.0 is 4.1σ; for the entire cluster sample we obtained an average M200 of 1.28 -0.21+0.23 × 1014 M⊙. Conclusions: Our measurements demonstrated the feasibility of using weak lensing magnification as a viable tool for determining the average halo masses for samples of high redshift galaxy clusters. The results also established the success of using galaxy over-densities to select massive clusters at z

  19. Absolute absorption cross sections of ozone at 300 K, 228 K and 195 K in the wavelength region 185-240 nm

    NASA Technical Reports Server (NTRS)

    Yoshino, K.; Parkinson, W. H.; Freeman, D. E.

    1992-01-01

    An account is given of progress of work on absorption cross section measurements of ozone at 300 K, 228 K and 195 K in the wavelength region 185-240 nm. In this wavelength region, the penetration of solar radiation into the Earth's atmosphere is controlled by O2 and O3. The transmitted radiation is available to dissociate trace species such as halocarbons and nitrous oxide. We have recently measured absolute absorption cross sections of O3 in the wavelength region 240-350 nm (Freeman et al., 1985; Yoshino et al., 1988). We apply these proven techniques to the determination of the absorption cross section of O3 at 300 K, 228 K and 195 K throughout the wavelength region 185-240 nm. A paper titled 'Absolute Absorption Cross Section Measurements of Ozone in the Wavelength Region 185-254 nm and the Temperature Dependence' has been submitted for publication in the Journal of Geophysical Research.

  20. Perceptions of firms within a cluster regarding the cluster's function and success: Amish furniture manufacturing in Ohio

    Treesearch

    Matthew S. Bumgardner; Gary W. Graham; P. Charles Goebel; Robert L. Romig

    2011-01-01

    The Amish-based furniture manufacturing cluster in and around Holmes County, OH, is home to some 400 shops and has become an important regional driver of demand for hardwood products. The cluster has expanded even as the broader domestic furniture industry has declined. Clustering dynamics are seen as important to the success, but little information has been available...

  1. Manipulation of visible-light polarization with dendritic cell-cluster metasurfaces.

    PubMed

    Fang, Zhen-Hua; Chen, Huan; An, Di; Luo, Chun-Rong; Zhao, Xiao-Peng

    2018-06-26

    Cross-polarization conversion plays an important role in visible light manipulation. Metasurface with asymmetric structure can be used to achieve polarization conversion of linearly polarized light. Based on this, we design a quasi-periodic dendritic metasurface model composed of asymmetric dendritic cells. The simulation indicates that the asymmetric dendritic structure can vertically rotate the polarization direction of the linear polarization wave in visible light. Silver dendritic cell-cluster metasurface samples were prepared by the bottom-up electrochemical deposition. It experimentally proved that they could realize the cross - polarization conversion in visible light. Cross-polarized propagating light is deflected into anomalous refraction channels. Dendritic cell-cluster metasurface with asymmetric quasi-periodic structure conveys significance in cross-polarization conversion research and features extensive practical application prospect and development potential.

  2. Star Clusters within FIRE

    NASA Astrophysics Data System (ADS)

    Perez, Adrianna; Moreno, Jorge; Naiman, Jill; Ramirez-Ruiz, Enrico; Hopkins, Philip F.

    2017-01-01

    In this work, we analyze the environments surrounding star clusters of simulated merging galaxies. Our framework employs Feedback In Realistic Environments (FIRE) model (Hopkins et al., 2014). The FIRE project is a high resolution cosmological simulation that resolves star forming regions and incorporates stellar feedback in a physically realistic way. The project focuses on analyzing the properties of the star clusters formed in merging galaxies. The locations of these star clusters are identified with astrodendro.py, a publicly available dendrogram algorithm. Once star cluster properties are extracted, they will be used to create a sub-grid (smaller than the resolution scale of FIRE) of gas confinement in these clusters. Then, we can examine how the star clusters interact with these available gas reservoirs (either by accreting this mass or blowing it out via feedback), which will determine many properties of the cluster (star formation history, compact object accretion, etc). These simulations will further our understanding of star formation within stellar clusters during galaxy evolution. In the future, we aim to enhance sub-grid prescriptions for feedback specific to processes within star clusters; such as, interaction with stellar winds and gas accretion onto black holes and neutron stars.

  3. Prospects for Formation and Development of the Geographical (Territorial) Industrial Clusters in West Kazakhstan Region of the Republic of Kazakhstan

    ERIC Educational Resources Information Center

    Imashev, Eduard Zh.

    2016-01-01

    The purpose of this research is to develop and implement an economic and geographic approach to forming and developing geographic (territorial) industrial clusters in regions of Kazakhstan. The purpose necessitates the accomplishment of the following scientific objectives: to investigate scientific approaches and experience of territorial economic…

  4. Performance map of a cluster detection test using extended power

    PubMed Central

    2013-01-01

    Background Conventional power studies possess limited ability to assess the performance of cluster detection tests. In particular, they cannot evaluate the accuracy of the cluster location, which is essential in such assessments. Furthermore, they usually estimate power for one or a few particular alternative hypotheses and thus cannot assess performance over an entire region. Takahashi and Tango developed the concept of extended power that indicates both the rate of null hypothesis rejection and the accuracy of the cluster location. We propose a systematic assessment method, using here extended power, to produce a map showing the performance of cluster detection tests over an entire region. Methods To explore the behavior of a cluster detection test on identical cluster types at any possible location, we successively applied four different spatial and epidemiological parameters. These parameters determined four cluster collections, each covering the entire study region. We simulated 1,000 datasets for each cluster and analyzed them with Kulldorff’s spatial scan statistic. From the area under the extended power curve, we constructed a map for each parameter set showing the performance of the test across the entire region. Results Consistent with previous studies, the performance of the spatial scan statistic increased with the baseline incidence of disease, the size of the at-risk population and the strength of the cluster (i.e., the relative risk). Performance was heterogeneous, however, even for very similar clusters (i.e., similar with respect to the aforementioned factors), suggesting the influence of other factors. Conclusions The area under the extended power curve is a single measure of performance and, although needing further exploration, it is suitable to conduct a systematic spatial evaluation of performance. The performance map we propose enables epidemiologists to assess cluster detection tests across an entire study region. PMID:24156765

  5. Statistical survey of day-side magnetospheric current flow using Cluster observations: magnetopause

    NASA Astrophysics Data System (ADS)

    Liebert, Evelyn; Nabert, Christian; Perschke, Christopher; Fornaçon, Karl-Heinz; Glassmeier, Karl-Heinz

    2017-05-01

    We present a statistical survey of current structures observed by the Cluster spacecraft at high-latitude day-side magnetopause encounters in the close vicinity of the polar cusps. Making use of the curlometer technique and the fluxgate magnetometer data, we calculate the 3-D current densities and investigate the magnetopause current direction, location, and magnitude during varying solar wind conditions. We find that the orientation of the day-side current structures is in accordance with existing magnetopause current models. Based on the ambient plasma properties, we distinguish five different transition regions at the magnetopause surface and observe distinctive current properties for each region. Additionally, we find that the location of currents varies with respect to the onset of the changes in the plasma environment during magnetopause crossings.

  6. Accuracies of genomic breeding values in American Angus beef cattle using K-means clustering for cross-validation.

    PubMed

    Saatchi, Mahdi; McClure, Mathew C; McKay, Stephanie D; Rolf, Megan M; Kim, JaeWoo; Decker, Jared E; Taxis, Tasia M; Chapple, Richard H; Ramey, Holly R; Northcutt, Sally L; Bauck, Stewart; Woodward, Brent; Dekkers, Jack C M; Fernando, Rohan L; Schnabel, Robert D; Garrick, Dorian J; Taylor, Jeremy F

    2011-11-28

    Genomic selection is a recently developed technology that is beginning to revolutionize animal breeding. The objective of this study was to estimate marker effects to derive prediction equations for direct genomic values for 16 routinely recorded traits of American Angus beef cattle and quantify corresponding accuracies of prediction. Deregressed estimated breeding values were used as observations in a weighted analysis to derive direct genomic values for 3570 sires genotyped using the Illumina BovineSNP50 BeadChip. These bulls were clustered into five groups using K-means clustering on pedigree estimates of additive genetic relationships between animals, with the aim of increasing within-group and decreasing between-group relationships. All five combinations of four groups were used for model training, with cross-validation performed in the group not used in training. Bivariate animal models were used for each trait to estimate the genetic correlation between deregressed estimated breeding values and direct genomic values. Accuracies of direct genomic values ranged from 0.22 to 0.69 for the studied traits, with an average of 0.44. Predictions were more accurate when animals within the validation group were more closely related to animals in the training set. When training and validation sets were formed by random allocation, the accuracies of direct genomic values ranged from 0.38 to 0.85, with an average of 0.65, reflecting the greater relationship between animals in training and validation. The accuracies of direct genomic values obtained from training on older animals and validating in younger animals were intermediate to the accuracies obtained from K-means clustering and random clustering for most traits. The genetic correlation between deregressed estimated breeding values and direct genomic values ranged from 0.15 to 0.80 for the traits studied. These results suggest that genomic estimates of genetic merit can be produced in beef cattle at a young age but

  7. Accuracies of genomic breeding values in American Angus beef cattle using K-means clustering for cross-validation

    PubMed Central

    2011-01-01

    Background Genomic selection is a recently developed technology that is beginning to revolutionize animal breeding. The objective of this study was to estimate marker effects to derive prediction equations for direct genomic values for 16 routinely recorded traits of American Angus beef cattle and quantify corresponding accuracies of prediction. Methods Deregressed estimated breeding values were used as observations in a weighted analysis to derive direct genomic values for 3570 sires genotyped using the Illumina BovineSNP50 BeadChip. These bulls were clustered into five groups using K-means clustering on pedigree estimates of additive genetic relationships between animals, with the aim of increasing within-group and decreasing between-group relationships. All five combinations of four groups were used for model training, with cross-validation performed in the group not used in training. Bivariate animal models were used for each trait to estimate the genetic correlation between deregressed estimated breeding values and direct genomic values. Results Accuracies of direct genomic values ranged from 0.22 to 0.69 for the studied traits, with an average of 0.44. Predictions were more accurate when animals within the validation group were more closely related to animals in the training set. When training and validation sets were formed by random allocation, the accuracies of direct genomic values ranged from 0.38 to 0.85, with an average of 0.65, reflecting the greater relationship between animals in training and validation. The accuracies of direct genomic values obtained from training on older animals and validating in younger animals were intermediate to the accuracies obtained from K-means clustering and random clustering for most traits. The genetic correlation between deregressed estimated breeding values and direct genomic values ranged from 0.15 to 0.80 for the traits studied. Conclusions These results suggest that genomic estimates of genetic merit can be

  8. Stellar Clusters in the NGC 6334 Star-Forming Complex

    NASA Astrophysics Data System (ADS)

    Feigelson, Eric D.; Martin, Amanda L.; McNeill, Collin J.; Broos, Patrick S.; Garmire, Gordon P.

    2009-07-01

    The full stellar population of NGC 6334, one of the most spectacular regions of massive star formation in the nearby Galaxy, has not been well sampled in past studies. We analyze here a mosaic of two Chandra X-ray Observatory images of the region using sensitive data analysis methods, giving a list of 1607 faint X-ray sources with arcsecond positions and approximate line-of-sight absorption. About 95% of these are expected to be cluster members, most lower mass pre-main-sequence stars. Extrapolating to low X-ray levels, the total stellar population is estimated to be 20,000-30,000 pre-main-sequence stars. The X-ray sources show a complicated spatial pattern with ~10 distinct star clusters. The heavily obscured clusters are mostly associated with previously known far-infrared sources and radio H II regions. The lightly obscured clusters are mostly newly identified in the X-ray images. Dozens of likely OB stars are found, both in clusters and dispersed throughout the region, suggesting that star formation in the complex has proceeded over millions of years. A number of extraordinarily heavily absorbed X-ray sources are associated with the active regions of star formation.

  9. Level crossings and zero-field splitting in the {Cr8}-cubane spin cluster studied using inelastic neutron scattering and magnetization

    NASA Astrophysics Data System (ADS)

    Vaknin, D.; Garlea, V. O.; Demmel, F.; Mamontov, E.; Nojiri, H.; Martin, C.; Chiorescu, I.; Qiu, Y.; Kögerler, P.; Fielden, J.; Engelhardt, L.; Rainey, C.; Luban, M.

    2010-11-01

    Inelastic neutron scattering (INS) in variable magnetic field and high-field magnetization measurements in the millikelvin temperature range were performed to gain insight into the low-energy magnetic excitation spectrum and the field-induced level crossings in the molecular spin cluster {Cr8}-cubane. These complementary techniques provide consistent estimates of the lowest level-crossing field. The overall features of the experimental data are explained using an isotropic Heisenberg model, based on three distinct exchange interactions linking the eight CrIII paramagnetic centers (spins s = 3/2), that is supplemented with a relatively large molecular magnetic anisotropy term for the lowest S = 1 multiplet. It is noted that the existence of the anisotropy is clearly evident from the magnetic field dependence of the excitations in the INS measurements, while the magnetization measurements are not sensitive to its effects.

  10. Level crossings and zero-field splitting in the {Cr8}-cubane spin-cluster studied using inelastic neutron scattering and magnetization

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Vaknin, D.; Garlea, Vasile O; Demmel, F.

    Inelastic neutron scattering (INS) in variable magnetic field and high-field magnetization measurements in the millikelvin temperature range were performed to gain insight into the low-energy magnetic excitation spectrum and the field-induced level crossings in the molecular spin cluster {Cr8}-cubane. These complementary techniques provide consistent estimates of the lowest level-crossing field. The overall features of the experimental data are explained using an isotropic Heisenberg model, based on three distinct exchange interactions linking the eight CrIII paramagnetic centers (spins s = 3/2), that is supplemented with a relatively large molecular magnetic anisotropy term for the lowest S = 1 multiplet. It ismore » noted that the existence of the anisotropy is clearly evident from the magnetic field dependence of the excitations in the INS measurements, while the magnetization measurements are not sensitive to its effects.« less

  11. 75 FR 53667 - Space Coast Regional Innovation Cluster Competition

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-01

    .../Defense, (4) Information Technology, and (5) Life Sciences. Please see Enterprise Florida's full strategy..., Information Technology, and Life Sciences industry clusters. Initiatives must engage stakeholders; facilitate...

  12. The Polar Cusp Observed by Cluster Under Constant Imf-Bz Southward

    NASA Astrophysics Data System (ADS)

    Escoubet, C. P.; Berchem, J.; Pitout, F.; Trattner, K. J.; Richard, R. L.; Taylor, M. G.; Soucek, J.; Grison, B.; Laakso, H. E.; Masson, A.; Dunlop, M. W.; Dandouras, I. S.; Reme, H.; Fazakerley, A. N.; Daly, P. W.

    2011-12-01

    The Earth's magnetic field is influenced by the interplanetary magnetic field (IMF), specially at the magnetopause where both magnetic fields enter in direct contact and magnetic reconnection can be initiated. In the polar regions, the polar cusp that extends from the magnetopause down to the ionosphere is also directly influenced. The reconnection not only allow ions and electrons from the solar wind to enter the polar cusp but also give an impulse to the magnetic field lines threading the polar cusp through the reconnection electric field. A dispersion in energy of the ions is subsequently produced by the motion of field lines and the time-of-flight effect on down-going ions. If reconnection is continuous and operates at constant rate, the ion dispersion is smooth and continuous. On the other hand if the reconnection rate varies, we expect interruption in the dispersion forming energy steps or staircase. Similarly, multiple entries near the magnetopause could also produce steps at low or mid-altitude when a spacecraft is crossing subsequently the field lines originating from these multiple sources. Cluster with four spacecraft following each other in the mid-altitude cusp can be used to distinguish between these "temporal" and "spatial" effects. We will show two Cluster cusp crossings where the spacecraft were separated by a few minutes. The energy dispersions observed in the first crossing were the same during the few minutes that separated the spacecraft. In the second crossing, two ion dispersions were observed on the first spacecraft and only one of the following spacecraft, about 10 min later. The detailed analysis indicates that these steps result from spatial structures.

  13. An analysis of infrared emission spectra from the regions near the Galactic Centre

    NASA Astrophysics Data System (ADS)

    Contini, Marcella

    2009-11-01

    We present consistent modelling of line and continuum infrared (IR) spectra in the region close to the Galactic Centre. The models account for the coupled effect of shocks and photoionization from an external source. The results show that the shock velocities range between ~65 and 80kms-1 and the pre-shock densities between 1cm-3 in the interstellar medium (ISM) to 200cm-3 in the filamentary structures. The pre-shock magnetic field increases from 5 × 10-6G in the surrounding ISM to ~8 × 10-5G in the arched filaments. The stellar temperatures are ~38000K in the Quintuplet cluster and ~27000K in the Arches Cluster. The ionization parameter is relatively low (<0.01) with the highest values near the clusters, reaching a maximum >0.01 near the Arches Cluster. Depletion from the gaseous phase of Si is found throughout the whole observed region, indicating the presence of silicate dust. Grains including iron are concentrated throughout the arched filaments. The modelling of the continuum spectral energy distribution in the IR range indicates that a component of dust at temperatures of ~100-200K is present in the central region of the Galaxy. Radio emission appears to be thermal bremsstrahlung in the E2-W1 filaments crossing strip; however, a synchrotron component is not excluded. More data are necessary to resolve these questions.

  14. Open clusters in Auriga OB2

    NASA Astrophysics Data System (ADS)

    Marco, Amparo; Negueruela, Ignacio

    2016-06-01

    We study the area around the H II region Sh 2-234, including the young open cluster Stock 8, to investigate the extent and definition of the association Aur OB2 and the possible role of triggering in massive cluster formation. We obtained Strömgren and J, H, KS photometry for Stock 8 and Strömgren photometry for two other cluster candidates in the area, which we confirm as young open clusters and name Alicante 11 and Alicante 12. We took spectroscopy of ˜33 early-type stars in the area, including the brightest cluster members. We calculate a common distance of 2.80^{+0.27}_{-0.24} kpc for the three open clusters and surrounding association. We derive an age 4-6 Ma for Stock 8, and do not find a significantly different age for the other clusters or the association. The star LS V +34°23, with spectral type O8 II(f), is likely the main source of ionization of Sh 2-234. We observe an important population of pre-main-sequence stars, some of them with discs, associated with the B-type members lying on the main sequence. We interpret the region as an area of recent star formation with some residual and very localized ongoing star formation. We do not find evidence for sequential star formation on a large scale. The classical definition of Aur OB2 has to be reconsidered, because its two main open clusters, Stock 8 and NGC 1893, are not at the same distance. Stock 8 is probably located in the Perseus arm, but other nearby H II regions whose distances also place them in this arm show quite different distances and radial velocities and, therefore, are not connected.

  15. Systematic detection and classification of earthquake clusters in Italy

    NASA Astrophysics Data System (ADS)

    Poli, P.; Ben-Zion, Y.; Zaliapin, I. V.

    2017-12-01

    We perform a systematic analysis of spatio-temporal clustering of 2007-2017 earthquakes in Italy with magnitudes m>3. The study employs the nearest-neighbor approach of Zaliapin and Ben-Zion [2013a, 2013b] with basic data-driven parameters. The results indicate that seismicity in Italy (an extensional tectonic regime) is dominated by clustered events, with smaller proportion of background events than in California. Evaluation of internal cluster properties allows separation of swarm-like from burst-like seismicity. This classification highlights a strong geographical coherence of cluster properties. Swarm-like seismicity are dominant in regions characterized by relatively slow deformation with possible elevated temperature and/or fluids (e.g. Alto Tiberina, Pollino), while burst-like seismicity are observed in crystalline tectonic regions (Alps and Calabrian Arc) and in Central Italy where moderate to large earthquakes are frequent (e.g. L'Aquila, Amatrice). To better assess the variation of seismicity style across Italy, we also perform a clustering analysis with region-specific parameters. This analysis highlights clear spatial changes of the threshold separating background and clustered seismicity, and permits better resolution of different clusters in specific geological regions. For example, a large proportion of repeaters is found in the Etna region as expected for volcanic-induced seismicity. A similar behavior is observed in the northern Apennines with high pore pressure associated with mantle degassing. The observed variations of earthquakes properties highlight shortcomings of practices using large-scale average seismic properties, and points to connections between seismicity and local properties of the lithosphere. The observations help to improve the understanding of the physics governing the occurrence of earthquakes in different regions.

  16. Young Cluster Berkeley 59: Properties, Evolution, and Star Formation

    NASA Astrophysics Data System (ADS)

    Panwar, Neelam; Pandey, A. K.; Samal, Manash R.; Battinelli, Paolo; Ogura, K.; Ojha, D. K.; Chen, W. P.; Singh, H. P.

    2018-01-01

    Berkeley 59 is a nearby (∼1 kpc) young cluster associated with the Sh2-171 H II region. We present deep optical observations of the central ∼2.5 × 2.5 pc2 area of the cluster, obtained with the 3.58 m Telescopio Nazionale Galileo. The V/(V–I) color–magnitude diagram manifests a clear pre-main-sequence (PMS) population down to ∼0.2 M ⊙. Using the near-infrared and optical colors of the low-mass PMS members, we derive a global extinction of A V = 4 mag and a mean age of ∼1.8 Myr, respectively, for the cluster. We constructed the initial mass function and found that its global slopes in the mass ranges of 0.2–28 M ⊙ and 0.2–1.5 M ⊙ are ‑1.33 and ‑1.23, respectively, in good agreement with the Salpeter value in the solar neighborhood. We looked for the radial variation of the mass function and found that the slope is flatter in the inner region than in the outer region, indicating mass segregation. The dynamical status of the cluster suggests that the mass segregation is likely primordial. The age distribution of the PMS sources reveals that the younger sources appear to concentrate close to the inner region compared to the outer region of the cluster, a phenomenon possibly linked to the time evolution of star-forming clouds. Within the observed area, we derive a total mass of ∼103 M ⊙ for the cluster. Comparing the properties of Berkeley 59 with other young clusters, we suggest it resembles more closely the Trapezium cluster.

  17. A search for quasars in the Virgo cluster region

    NASA Technical Reports Server (NTRS)

    He, X.-T.; Cannon, R. D.; Peacock, J. A.; Smith, M. G.; Oke, J. B.

    1984-01-01

    Using objective-prism plates taken with the 44-arcmin objective prism mounted on the UK Schmidt telescope, 53 emission-line quasar candidates and 29 ultraviolet-excess objects (possible low-redshift quasars) have been found in a 5 x 5-degree field centered on 12 h 27 m, + 13 deg 30 min (1950) in the Virgo cluster of galaxies. Eighteen of these 82 candidates were observed using the double spectrograph on the Palomar 5-meter telescope; 13 of the observed objects proved to be quasars. The broad-absorption-line QSO Q1232 + 134 is the first example of the class to show broad low-ionization absorption lines (such as Mg II 2798 A) in addition to the usual high-excitation lines such as Nv 1240 A. Although no conclusive evidence for quasar-galaxy associations is found in this field, there do exist nonuniformities in the distribution of the quasar candidates which may merit further investigation. These objects will provide a useful network of probes for absorbing material in the Virgo cluster. The lines-of-sight to two of the confirmed quasars pass very close to NGC galaxies; the respective projected QSO-galaxy separations are only 4 and 11 kpc at the assumed distance of the Virgo cluster.

  18. Clustering of diet- and activity-related parenting practices: cross-sectional findings of the INPACT study

    PubMed Central

    2013-01-01

    Background Various diet- and activity-related parenting practices are positive determinants of child dietary and activity behaviour, including home availability, parental modelling and parental policies. There is evidence that parenting practices cluster within the dietary domain and within the activity domain. This study explores whether diet- and activity-related parenting practices cluster across the dietary and activity domain. Also examined is whether the clusters are related to child and parental background characteristics. Finally, to indicate the relevance of the clusters in influencing child dietary and activity behaviour, we examined whether clusters of parenting practices are related to these behaviours. Methods Data were used from 1480 parent–child dyads participating in the Dutch IVO Nutrition and Physical Activity Child cohorT (INPACT). Parents of children aged 8–11 years completed questionnaires at home assessing their diet- and activity-related parenting practices, child and parental background characteristics, and child dietary and activity behaviours. Principal component analysis (PCA) was used to identify clusters of parenting practices. Backward regression analysis was used to examine the relationship between child and parental background characteristics with cluster scores, and partial correlations to examine associations between cluster scores and child dietary and activity behaviours. Results PCA revealed five clusters of parenting practices: 1) high visibility and accessibility of screens and unhealthy food, 2) diet- and activity-related rules, 3) low availability of unhealthy food, 4) diet- and activity-related positive modelling, and 5) positive modelling on sports and fruit. Low parental education was associated with unhealthy cluster 1, while high(er) education was associated with healthy clusters 2, 3 and 5. Separate clusters were related to both child dietary and activity behaviour in the hypothesized directions: healthy clusters

  19. MYStIX: Dynamical evolution of young clusters

    NASA Astrophysics Data System (ADS)

    Kuhn, Michael A.

    2014-08-01

    The spatial structure of young stellar clusters in Galactic star-forming regions provides insight into these clusters’ dynamical evolution---a topic with implications for open questions in star-formation and cluster survival. The Massive Young Star-Forming Complex Study in Infrared and X-ray (MYStIX) provides a sample of >30,000 young stars in star-forming regions (d<3.6 kpc) that contain at least one O-type star. We use the finite mixture model analysis to identify subclusters of stars and determine their properties: including subcluster radii, intrinsic numbers of stars, central density, ellipticity, obscuration, and age. In 17 MYStIX regions we find 142 subclusters, with a diverse radii and densities and age spreads of up to ~1 Myr in a region. There is a strong negative correlation between subcluster radius and density, which indicates that embedded subclusters expand but also gain stars as they age. Subcluster expansion is also shown by a positive radius--age correlation, which indicates that subclusters are expanding at <1 km/s. The subcluster ellipticity distribution and number--density relation show signs of a hierarchical merger scenario, whereby young stellar clusters are built up through mergers of smaller clumps, causing evolution from a clumpy spatial distribution of stars (seen in some regions) to a simpler distribution of stars (seen in other regions). Many of the simple young stellar clusters show signs of dynamically relaxation, even though they are not old enough for this to have occurred through two-body interactions. However, this apparent contradiction might be explained if small subcluster, which have shorter dynamical relaxation times, can produce dynamically relaxed clusters through hierarchical mergers.

  20. The XMM Cluster Outskirts Project (X-COP)

    NASA Astrophysics Data System (ADS)

    Eckert, D.

    2017-10-01

    The outskirts of galaxy clusters (typically the regions located beyond R500) are the regions where the transition between the virialized ICM and the infalling material from the large-scale structure takes place. As such, they play a central role in our understanding of the processes leading to the virialization of the accreting gas within the central dark-matter halo. I will give an overview of the XMM cluster outskirts project (X-COP), a very large program on XMM to study the virial region of galaxy clusters with unprecedented details. I will show how X-ray observations can be combined with the Sunyaev-Zeldovich signal to recover the thermodynamic properties and hydrostatic mass of the ICM, bypassing the need for expensive X-ray spectroscopic observations. I will discuss the results obtained using this technique on Abell 2142 and Abell 2319 and give prospects for the results expected using the full X-COP sample. I will also present recent results on the search for warm-hot baryons in the filaments connected to clusters, emphasizing on the discovery of 3 filaments of 10-million-degree gas connected to the massive cluster Abell 2744.

  1. Exploring Large-Scale Cross-Correlation for Teleseismic and Regional Seismic Event Characterization

    NASA Astrophysics Data System (ADS)

    Dodge, Doug; Walter, William; Myers, Steve; Ford, Sean; Harris, Dave; Ruppert, Stan; Buttler, Dave; Hauk, Terri

    2013-04-01

    The decrease in costs of both digital storage space and computation power invites new methods of seismic data processing. At Lawrence Livermore National Laboratory(LLNL) we operate a growing research database of seismic events and waveforms for nuclear explosion monitoring and other applications. Currently the LLNL database contains several million events associated with tens of millions of waveforms at thousands of stations. We are making use of this database to explore the power of seismic waveform correlation to quantify signal similarities, to discover new events not in catalogs, and to more accurately locate events and identify source types. Building on the very efficient correlation methodologies of Harris and Dodge (2011) we computed the waveform correlation for event pairs in the LLNL database in two ways. First we performed entire waveform cross-correlation over seven distinct frequency bands. The correlation coefficient exceeds 0.6 for more than 40 million waveform pairs for several hundred thousand events at more than a thousand stations. These correlations reveal clusters of mining events and aftershock sequences, which can be used to readily identify and locate events. Second we determine relative pick times by correlating signals in time windows for distinct seismic phases. These correlated picks are then used to perform very high accuracy event relocations. We are examining the percentage of events that correlate as a function of magnitude and observing station distance in selected high seismicity regions. Combining these empirical results and those using synthetic data, we are working to quantify relationships between correlation and event pair separation (in epicenter and depth) as well as mechanism differences. Our exploration of these techniques on a large seismic database is in process and we will report on our findings in more detail at the meeting.

  2. Exploring Large-Scale Cross-Correlation for Teleseismic and Regional Seismic Event Characterization

    NASA Astrophysics Data System (ADS)

    Dodge, D.; Walter, W. R.; Myers, S. C.; Ford, S. R.; Harris, D.; Ruppert, S.; Buttler, D.; Hauk, T. F.

    2012-12-01

    The decrease in costs of both digital storage space and computation power invites new methods of seismic data processing. At Lawrence Livermore National Laboratory (LLNL) we operate a growing research database of seismic events and waveforms for nuclear explosion monitoring and other applications. Currently the LLNL database contains several million events associated with tens of millions of waveforms at thousands of stations. We are making use of this database to explore the power of seismic waveform correlation to quantify signal similarities, to discover new events not in catalogs, and to more accurately locate events and identify source types. Building on the very efficient correlation methodologies of Harris and Dodge (2011) we computed the waveform correlation for event pairs in the LLNL database in two ways. First we performed entire waveform cross-correlation over seven distinct frequency bands. The correlation coefficient exceeds 0.6 for more than 40 million waveform pairs for several hundred thousand events at more than a thousand stations. These correlations reveal clusters of mining events and aftershock sequences, which can be used to readily identify and locate events. Second we determine relative pick times by correlating signals in time windows for distinct seismic phases. These correlated picks are then used to perform very high accuracy event relocations. We are examining the percentage of events that correlate as a function of magnitude and observing station distance in selected high seismicity regions. Combining these empirical results and those using synthetic data, we are working to quantify relationships between correlation and event pair separation (in epicenter and depth) as well as mechanism differences. Our exploration of these techniques on a large seismic database is in process and we will report on our findings in more detail at the meeting.

  3. Transition from one revolving cluster to two revolving clusters in the ground-state rotational bands of nuclei in the lanthanon region.

    PubMed

    Pauling, L

    1991-02-01

    Whereas 234(92)U142 and other actinon nuclei have ground-state bands that indicate that each nucleus consists of a sphere and a single revolving cluster with constant composition and with only a steady increase in the moment of inertia with increase in J, the angular-momentum quantum number, many of the lanthanon ground-state bands show discontinuities, usually with an initial slightly or strongly curved segment followed by one or two nearly straight segments. The transition to nearly straight segments is interpreted as a change in structure from one revolving cluster to two revolving clusters. The proton-neutron compositions of the clusters and the central sphere are assigned, leading to values of the radius of revolution. The approximation of the two-cluster sequences to linearity is attributed to the very small values of the quadrupole polarizability of the central sphere. Values of the nucleon numbers of clusters and spheres, of the radius of revolution, and of promotion energy are discussed.

  4. Thermal Conduction in Simulated Galaxy Clusters

    NASA Astrophysics Data System (ADS)

    Dolag, K.; Jubelgas, M.; Springel, V.; Borgani, S.; Rasia, E.

    2004-05-01

    We study the formation of clusters of galaxies using high-resolution hydrodynamic cosmological simulations that include the effect of thermal conduction with an effective isotropic conductivity of 1/3 the classical Spitzer value. We find that, for both a hot (TLX~=12 keV) and several cold (TLX~=2 keV) galaxy clusters, the baryonic fraction converted into stars does not change significantly when thermal conduction is included. However, the temperature profiles are modified, particularly in our simulated hot system, where an extended isothermal core is readily formed. As a consequence of heat flowing from the inner regions of the cluster both to its outer parts and into its innermost resolved regions, the entropy profile is altered as well. This effect is almost negligible for the cold cluster, as expected based on the strong temperature dependence of the conductivity. Our results demonstrate that while thermal conduction can have a significant influence on the properties of the intracluster medium (ICM) of rich clusters, it appears unlikely to provide by itself a solution for the overcooling problem in clusters or to explain the current discrepancies between the observed and simulated properties of the ICM.

  5. Cluster analysis of multiple planetary flow regimes

    NASA Technical Reports Server (NTRS)

    Mo, Kingtse; Ghil, Michael

    1987-01-01

    A modified cluster analysis method was developed to identify spatial patterns of planetary flow regimes, and to study transitions between them. This method was applied first to a simple deterministic model and second to Northern Hemisphere (NH) 500 mb data. The dynamical model is governed by the fully-nonlinear, equivalent-barotropic vorticity equation on the sphere. Clusters of point in the model's phase space are associated with either a few persistent or with many transient events. Two stationary clusters have patterns similar to unstable stationary model solutions, zonal, or blocked. Transient clusters of wave trains serve as way stations between the stationary ones. For the NH data, cluster analysis was performed in the subspace of the first seven empirical orthogonal functions (EOFs). Stationary clusters are found in the low-frequency band of more than 10 days, and transient clusters in the bandpass frequency window between 2.5 and 6 days. In the low-frequency band three pairs of clusters determine, respectively, EOFs 1, 2, and 3. They exhibit well-known regional features, such as blocking, the Pacific/North American (PNA) pattern and wave trains. Both model and low-pass data show strong bimodality. Clusters in the bandpass window show wave-train patterns in the two jet exit regions. They are related, as in the model, to transitions between stationary clusters.

  6. The Ophiuchus cluster - A bright X-ray cluster of galaxies at low galactic latitude

    NASA Technical Reports Server (NTRS)

    Johnston, M. D.; Bradt, H. V.; Doxsey, R. E.; Marshall, F. E.; Schwartz, D. A.; Margon, B.

    1981-01-01

    The discovery of an extended X-ray source identified with a cluster of galaxies at low galactic latitude is reported. The source, designated the Ophiuchus cluster, was detected near 4U 1708-23 with the HEAO 1 Scanning Modulation Collimator, and identified with the cluster on the basis of extended X-ray size and positional coincidence on the ESO/SRC (J) plate of the region. An X-ray flux density in the region 2-10 keV of approximately 25 microJ was measured, along with an X-ray luminosity of 1.6 x 10 to the 45th ergs/sec and an X-ray core radius of approximately 4 arcmin (0.2 Mpc) for an assumed isothermal sphere surface brightness distribution. The X-ray spectrum in the range 2-10 keV obtained with the HEAO 1 A-2 instrument is well fit by a thermal bremsstrahlung model with kT = 8 keV and a 6.7-keV iron line of equivalent width 450 eV. The steep-spectrum radio source MSH 17-203 also appears to be associated with the cluster, which is the closest and brightest representative of the class of X-ray clusters with a dominant central galaxy.

  7. The Clusters AgeS Experiment (CASE). Variable Stars in the Field of the Globular Cluster NGC 6362

    NASA Astrophysics Data System (ADS)

    Kaluzny, J.; Thompson, I. B.; Rozyczka, M.; Pych, W.; Narloch, W.

    2014-12-01

    The field of the globular cluster NGC 6362 was monitored between 1995 and 2009 in a search for variable stars. BV light curves were obtained for 69 periodic variable stars including 34 known RR Lyr stars, 10 known objects of other types and 25 newly detected variable stars. Among the latter we identified 18 proper-motion members of the cluster: seven detached eclipsing binaries (DEBs), six SX Phe stars, two W UMa binaries, two spotted red giants, and a very interesting eclipsing binary composed of two red giants - the first example of such a system found in a globular cluster. Five of the DEBs are located at the turnoff region, and the remaining two are redward of the lower main sequence. Eighty-four objects from the central 9×9 arcmin2 of the cluster were found in the region of cluster blue stragglers. Of these 70 are proper motion (PM) members of NGC 6362 (including all SX Phe and two W UMa stars), and five are field stars. The remaining nine objects lacking PM information are located at the very core of the cluster, and as such they are likely genuine blue stragglers.

  8. Creating multithemed ecological regions for macroscale ecology: Testing a flexible, repeatable, and accessible clustering method.

    PubMed

    Cheruvelil, Kendra Spence; Yuan, Shuai; Webster, Katherine E; Tan, Pang-Ning; Lapierre, Jean-François; Collins, Sarah M; Fergus, C Emi; Scott, Caren E; Henry, Emily Norton; Soranno, Patricia A; Filstrup, Christopher T; Wagner, Tyler

    2017-05-01

    Understanding broad-scale ecological patterns and processes often involves accounting for regional-scale heterogeneity. A common way to do so is to include ecological regions in sampling schemes and empirical models. However, most existing ecological regions were developed for specific purposes, using a limited set of geospatial features and irreproducible methods. Our study purpose was to: (1) describe a method that takes advantage of recent computational advances and increased availability of regional and global data sets to create customizable and reproducible ecological regions, (2) make this algorithm available for use and modification by others studying different ecosystems, variables of interest, study extents, and macroscale ecology research questions, and (3) demonstrate the power of this approach for the research question-How well do these regions capture regional-scale variation in lake water quality? To achieve our purpose we: (1) used a spatially constrained spectral clustering algorithm that balances geospatial homogeneity and region contiguity to create ecological regions using multiple terrestrial, climatic, and freshwater geospatial data for 17 northeastern U.S. states (~1,800,000 km 2 ); (2) identified which of the 52 geospatial features were most influential in creating the resulting 100 regions; and (3) tested the ability of these ecological regions to capture regional variation in water nutrients and clarity for ~6,000 lakes. We found that: (1) a combination of terrestrial, climatic, and freshwater geospatial features influenced region creation, suggesting that the oft-ignored freshwater landscape provides novel information on landscape variability not captured by traditionally used climate and terrestrial metrics; and (2) the delineated regions captured macroscale heterogeneity in ecosystem properties not included in region delineation-approximately 40% of the variation in total phosphorus and water clarity among lakes was at the regional

  9. Method and system for data clustering for very large databases

    NASA Technical Reports Server (NTRS)

    Livny, Miron (Inventor); Zhang, Tian (Inventor); Ramakrishnan, Raghu (Inventor)

    1998-01-01

    Multi-dimensional data contained in very large databases is efficiently and accurately clustered to determine patterns therein and extract useful information from such patterns. Conventional computer processors may be used which have limited memory capacity and conventional operating speed, allowing massive data sets to be processed in a reasonable time and with reasonable computer resources. The clustering process is organized using a clustering feature tree structure wherein each clustering feature comprises the number of data points in the cluster, the linear sum of the data points in the cluster, and the square sum of the data points in the cluster. A dense region of data points is treated collectively as a single cluster, and points in sparsely occupied regions can be treated as outliers and removed from the clustering feature tree. The clustering can be carried out continuously with new data points being received and processed, and with the clustering feature tree being restructured as necessary to accommodate the information from the newly received data points.

  10. Spatio-Temporal Clustering of Monitoring Network

    NASA Astrophysics Data System (ADS)

    Hussain, I.; Pilz, J.

    2009-04-01

    Pakistan has much diversity in seasonal variation of different locations. Some areas are in desserts and remain very hot and waterless, for example coastal areas are situated along the Arabian Sea and have very warm season and a little rainfall. Some areas are covered with mountains, have very low temperature and heavy rainfall; for instance Karakoram ranges. The most important variables that have an impact on the climate are temperature, precipitation, humidity, wind speed and elevation. Furthermore, it is hard to find homogeneous regions in Pakistan with respect to climate variation. Identification of homogeneous regions in Pakistan can be useful in many aspects. It can be helpful for prediction of the climate in the sub-regions and for optimizing the number of monitoring sites. In the earlier literature no one tried to identify homogeneous regions of Pakistan with respect to climate variation. There are only a few papers about spatio-temporal clustering of monitoring network. Steinhaus (1956) presented the well-known K-means clustering method. It can identify a predefined number of clusters by iteratively assigning centriods to clusters based. Castro et al. (1997) developed a genetic heuristic algorithm to solve medoids based clustering. Their method is based on genetic recombination upon random assorting recombination. The suggested method is appropriate for clustering the attributes which have genetic characteristics. Sap and Awan (2005) presented a robust weighted kernel K-means algorithm incorporating spatial constraints for clustering climate data. The proposed algorithm can effectively handle noise, outliers and auto-correlation in the spatial data, for effective and efficient data analysis by exploring patterns and structures in the data. Soltani and Modarres (2006) used hierarchical and divisive cluster analysis to categorize patterns of rainfall in Iran. They only considered rainfall at twenty-eight monitoring sites and concluded that eight clusters

  11. Towards the high-accuracy determination of the 238U fission cross section at the threshold region at CERN - n_TOF

    NASA Astrophysics Data System (ADS)

    Diakaki, M.; Audouin, L.; Berthoumieux, E.; Calviani, M.; Colonna, N.; Dupont, E.; Duran, I.; Gunsing, F.; Leal-Cidoncha, E.; Le Naour, C.; Leong, L. S.; Mastromarco, M.; Paradela, C.; Tarrio, D.; Tassan-Got, L.; Aerts, G.; Altstadt, S.; Alvarez, H.; Alvarez-Velarde, F.; Andriamonje, S.; Andrzejewski, J.; Badurek, G.; Barbagallo, M.; Baumann, P.; Becares, V.; Becvar, F.; Belloni, F.; Berthier, B.; Billowes, J.; Boccone, V.; Bosnar, D.; Brugger, M.; Calvino, F.; Cano-Ott, D.; Capote, R.; Carrapiço, C.; Cennini, P.; Cerutti, F.; Chiaveri, E.; Chin, M.; Cortes, G.; Cortes-Giraldo, M. A.; Cosentino, L.; Couture, A.; Cox, J.; David, S.; Dillmann, I.; Domingo-Pardo, C.; Dressler, R.; Dridi, W.; Eleftheriadis, C.; Embid-Segura, M.; Ferrant, L.; Ferrari, A.; Finocchiaro, P.; Fraval, K.; Fujii, K.; Furman, W.; Ganesan, S.; Garcia, A. R.; Giubrone, G.; Gomez-Hornillos, M. B.; Goncalves, I. F.; Gonzalez-Romero, E.; Goverdovski, A.; Gramegna, F.; Griesmayer, E.; Guerrero, C.; Gurusamy, P.; Haight, R.; Heil, M.; Heinitz, S.; Igashira, M.; Isaev, S.; Jenkins, D. G.; Jericha, E.; Kadi, Y.; Kaeppeler, F.; Karadimos, D.; Karamanis, D.; Kerveno, M.; Ketlerov, V.; Kivel, N.; Kokkoris, M.; Konovalov, V.; Krticka, M.; Kroll, J.; Lampoudis, C.; Langer, C.; Lederer, C.; Leeb, H.; Lo Meo, S.; Losito, R.; Lozano, M.; Manousos, A.; Marganiec, J.; Martinez, T.; Marrone, S.; Massimi, C.; Mastinu, P.; Mendoza, E.; Mengoni, A.; Milazzo, P. M.; Mingrone, F.; Mirea, M.; Mondelaers, W.; Moreau, C.; Mosconi, M.; Musumarra, A.; O'Brien, S.; Pancin, J.; Patronis, N.; Pavlik, A.; Pavlopoulos, P.; Perkowski, J.; Perrot, L.; Pigni, M. T.; Plag, R.; Plompen, A.; Plukis, L.; Poch, A.; Pretel, C.; Praena, J.; Quesada, J.; Rauscher, T.; Reifarth, R.; Riego, A.; Roman, F.; Rudolf, G.; Rubbia, C.; Rullhusen, P.; Salgado, J.; Santos, C.; Sarchiapone, L.; Sarmento, R.; Saxena, A.; Schillebeeckx, P.; Schmidt, S.; Schumann, D.; Stephan, C.; Tagliente, G.; Tain, J. L.; Tavora, L.; Terlizzi, R.; Tsinganis, A.; Valenta, S.; Vannini, G.; Variale, V.; Vaz, P.; Ventura, A.; Versaci, R.; Vermeulen, M. J.; Villamarin, D.; Vincente, M. C.; Vlachoudis, V.; Vlastou, R.; Voss, F.; Wallner, A.; Walter, S.; Ware, T.; Weigand, M.; Weiß, C.; Wiesher, M.; Wisshak, K.; Wright, T.; Zugec, P.

    2016-03-01

    The 238U fission cross section is an international standard beyond 2 MeV where the fission plateau starts. However, due to its importance in fission reactors, this cross-section should be very accurately known also in the threshold region below 2 MeV. The 238U fission cross section has been measured relative to the 235U fission cross section at CERN - n_TOF with different detection systems. These datasets have been collected and suitably combined to increase the counting statistics in the threshold region from about 300 keV up to 3 MeV. The results are compared with other experimental data, evaluated libraries, and the IAEA standards.

  12. Cluster-cluster clustering

    NASA Technical Reports Server (NTRS)

    Barnes, J.; Dekel, A.; Efstathiou, G.; Frenk, C. S.

    1985-01-01

    The cluster correlation function xi sub c(r) is compared with the particle correlation function, xi(r) in cosmological N-body simulations with a wide range of initial conditions. The experiments include scale-free initial conditions, pancake models with a coherence length in the initial density field, and hybrid models. Three N-body techniques and two cluster-finding algorithms are used. In scale-free models with white noise initial conditions, xi sub c and xi are essentially identical. In scale-free models with more power on large scales, it is found that the amplitude of xi sub c increases with cluster richness; in this case the clusters give a biased estimate of the particle correlations. In the pancake and hybrid models (with n = 0 or 1), xi sub c is steeper than xi, but the cluster correlation length exceeds that of the points by less than a factor of 2, independent of cluster richness. Thus the high amplitude of xi sub c found in studies of rich clusters of galaxies is inconsistent with white noise and pancake models and may indicate a primordial fluctuation spectrum with substantial power on large scales.

  13. Radio Sources Toward Galaxy Clusters at 30 GHz

    NASA Technical Reports Server (NTRS)

    Coble, K.; Bonamente, M.; Carlstrom, J. E.; Dawson, K.; Hasler, N.; Holzapfel, W.; Joy, M.; LaRoque, S.; Marrone, D. P.; Reese, E. D.

    2007-01-01

    Extra-galactic radio sources are a significant contaminant in cosmic microwave background and Sunyaev-Zeldovich effect experiments. Deep interferometric observations with the BIMA and OVRO arrays are used to characterize the spatial, spectral, and flux distributions of radio sources toward massive galaxy clusters at 28.5 GHz. We compute counts of mJy source fluxes from 89 fields centered on known massive galaxy clusters and 8 non-cluster fields. We find that source counts in the inner regions of the cluster fields (within 0.5 arcmin of the cluster center) are a factor of 8.9 (+4.2 to -3.8) times higher than counts in the outer regions of the cluster fields (radius greater than 0.5 arcmin). Counts in the outer regions of the cluster fields are in turn a factor of 3.3 (+4.1 -1.8) greater than those in the noncluster fields. Counts in the non-cluster fields are consistent with extrapolations from the results of other surveys. We compute spectral indices of mJy sources in cluster fields between 1.4 and 28.5 GHz and find a mean spectral index of al[ja = 0.66 with an rms dispersion of 0.36, where flux S varies as upsilon(sup -alpha). The distribution is skewed, with a median spectral index of 0.72 and 25th and 75th percentiles of 0.51 and 0.92, respectively. This is steeper than the spectral indices of stronger field sources measured by other surveys.

  14. Probing dark matter physics with galaxy clusters

    NASA Astrophysics Data System (ADS)

    Dalal, Neal

    2016-10-01

    We propose a theoretical investigation of the effects of a class of dark matter (DM) self-interactions on the properties of galaxy clusters and their host dark matter halos. Recent work using HST has claimed the detection of a particular form of DM self-interaction, which can lead to observable displacements between satellite galaxies within clusters and the DM subhalos hosting them. This form of self-interaction is highly anisotropic, favoring forward scattering with low momentum transfer, unlike isotropically scattering self-interacting dark matter (SIDM) models. This class of models has not been simulated numerically, clouding the interpretation of the claimed offsets between galaxies and lensing peaks observed by HST. We propose to perform high resolution simulations of cosmological structure formation for this class of SIDM model, focusing on three observables accessible to existing HST observations of clusters. First, we will quantify the extent to which offsets between baryons and DM can arise in these models, as a function of the cross section. Secondly, we will also quantify the effects of this type of DM self-interaction on halo concentrations, to determine the range of cross-sections allowed by existing stringent constraints from HST. Finally we will compute the so-called splashback feature in clusters, specifically focusing on whether SIDM can resolve the current discrepancy between observed values of splashback radii in clusters compared to theoretical predictions for CDM. The proposed investigations will add value to all existing deep HST observations of galaxy clusters by allowing them to probe dark matter physics in three independent ways.

  15. Cluster mass estimators from CMB temperature and polarization lensing

    NASA Astrophysics Data System (ADS)

    Hu, Wayne; DeDeo, Simon; Vale, Chris

    2007-12-01

    Upcoming Sunyaev Zel'dovich surveys are expected to return ~104 intermediate mass clusters at high redshift. Their average masses must be known to the same accuracy as desired for the dark energy properties. Internal to the surveys, the cosmic microwave background (CMB) potentially provides a source for lensing mass measurements whose distance is precisely known and behind all clusters. We develop statistical mass estimators from six quadratic combinations of CMB temperature and polarization fields that can simultaneously recover large-scale structure and cluster mass profiles. The performance of these estimators on idealized Navarro Frenk White (NFW) clusters suggests that surveys with a ~1' beam and 10\\,\\muK^{\\prime} noise in uncontaminated temperature maps can make a ~10σ detection, or equivalently a ~10% mass measurement for each 103 set of clusters. With internal or external acoustic scale E-polarization measurements, the ET cross-correlation estimator can provide a stringent test for contaminants on a first detection at ~1/3 the significance. For surveys that reach below 3\\,\\muK^{\\prime}, the EB cross-correlation estimator should provide the most precise measurements and potentially the strongest control over contaminants.

  16. National Differences in Regional Emergency Department Boarding Times: Are US Emergency Departments Prepared for a Public Health Emergency?

    PubMed

    Love, Jennifer S; Karp, David; Delgado, M Kit; Margolis, Gregg; Wiebe, Douglas J; Carr, Brendan G

    2016-08-01

    Boarding admitted patients decreases emergency department (ED) capacity to accommodate daily patient surge. Boarding in regional hospitals may decrease the ability to meet community needs during a public health emergency. This study examined differences in regional patient boarding times across the United States and in regions at risk for public health emergencies. A retrospective cross-sectional analysis was performed by using 2012 ED visit data from the American Hospital Association (AHA) database and 2012 hospital ED boarding data from the Centers for Medicare and Medicaid Services Hospital Compare database. Hospitals were grouped into hospital referral regions (HRRs). The primary outcome was mean ED boarding time per HRR. Spatial hot spot analysis examined boarding time spatial clustering. A total of 3317 of 4671 (71%) hospitals were included in the study cohort. A total of 45 high-boarding-time HRRs clustered along the East/West coasts and 67 low-boarding-time HRRs clustered in the Midwest/Northern Plains regions. A total of 86% of HRRs at risk for a terrorist event had high boarding times and 36% of HRRs with frequent natural disasters had high boarding times. Urban, coastal areas have the longest boarding times and are clustered with other high-boarding-time HRRs. Longer boarding times suggest a heightened level of vulnerability and a need to enhance surge capacity because these regions have difficulty meeting daily emergency care demands and are at increased risk for disasters. (Disaster Med Public Health Preparedness. 2016;10:576-582).

  17. Phospholipase A1-based cross-reactivity among venoms of clinically relevant Hymenoptera from Neotropical and temperate regions.

    PubMed

    Perez-Riverol, Amilcar; Fernandes, Luís Gustavo Romani; Musacchio Lasa, Alexis; Dos Santos-Pinto, José Roberto Aparecido; Moitinho Abram, Débora; Izuka Moraes, Gabriel Hideki; Jabs, Frederic; Miehe, Michaela; Seismman, Henning; Palma, Mario Sergio; de Lima Zollner, Ricardo; Spillner, Edzard; Brochetto-Braga, Márcia Regina

    2018-01-01

    Molecular cross-reactivity caused by allergen homology or cross-reactive carbohydrate determinants (CCDs) is a major challenge for diagnosis and immunotherapy of insect venom allergy. Venom phospholipases A1 (PLA1s) are classical, mostly non-glycosylated wasp and ant allergens that provide diagnostic benefit for differentiation of genuine sensitizations from cross-reactivity. As CCD-free molecules, venom PLA1s are not causative for CCD-based cross-reactivity. Little is known however about the protein-based cross-reactivity of PLA1 within vespid species. Here, we address PLA1-based cross-reactivity among ten clinically relevant Hymenoptera venoms from Neotropical and temperate regions including Polybia paulista (paulistinha) venom and Vespula vulgaris (yellow jacket) venom. In order to evaluate cross-reactivity, sera of mice sensitized with recombinant PLA1 (rPoly p 1) from P. paulista wasp venom were used. Pronounced IgE and IgG based cross-reactivity was detected for wasp venoms regardless the geographical region of origin. The cross-reactivity correlated well with the identity of the primary sequence and 3-D models of PLA1 proteins. In contrast, these mice sera showed no reaction with honeybee (HBV) and fire ant venom. Furthermore, sera from patients monosensitized to HBV and fire ants did not recognize the rPoly p 1 in immunoblotting. Our findings reveal the presence of conserved epitopes in the PLA1s from several clinically relevant wasps as major cause of PLA1-based in vitro cross-reactivity. These findings emphasize the limitations but also the potential of PLA1-based HVA diagnostics. Copyright © 2017 Elsevier Ltd. All rights reserved.

  18. High resolution absorption cross sections in the transmission window region of the Schumann-Runge bands and Herzberg continuum of O2

    NASA Technical Reports Server (NTRS)

    Yoshino, K.; Esmond, J. R.; Cheung, A. S.-C.; Freeman, D. E.; Parkinson, W. H.

    1992-01-01

    Results are presented on measurements, conducted in the wavelength region 180-195 nm, and at different pressures of oxygen (between 2.5-760 torr) in order to separate the pressure-dependent absorption from the main cross sections, of the absorption cross sections of the Schumann-Runge bands in the window region between the rotational lines of S-R bands of O2. The present cross sections supersede the earlier published cross sections (Yoshino et al., 1983). The combined cross sections are presented graphically; they are available at wavenumber intervals of about 0.1/cm from the National Space Science Data Center. The Herzberg continuum cross sections are derived after subtracting calculated contributions from the Schumann-Runge bands. These are significantly smaller than any previous measurements.

  19. Data Clustering

    NASA Astrophysics Data System (ADS)

    Wagstaff, Kiri L.

    2012-03-01

    On obtaining a new data set, the researcher is immediately faced with the challenge of obtaining a high-level understanding from the observations. What does a typical item look like? What are the dominant trends? How many distinct groups are included in the data set, and how is each one characterized? Which observable values are common, and which rarely occur? Which items stand out as anomalies or outliers from the rest of the data? This challenge is exacerbated by the steady growth in data set size [11] as new instruments push into new frontiers of parameter space, via improvements in temporal, spatial, and spectral resolution, or by the desire to "fuse" observations from different modalities and instruments into a larger-picture understanding of the same underlying phenomenon. Data clustering algorithms provide a variety of solutions for this task. They can generate summaries, locate outliers, compress data, identify dense or sparse regions of feature space, and build data models. It is useful to note up front that "clusters" in this context refer to groups of items within some descriptive feature space, not (necessarily) to "galaxy clusters" which are dense regions in physical space. The goal of this chapter is to survey a variety of data clustering methods, with an eye toward their applicability to astronomical data analysis. In addition to improving the individual researcher’s understanding of a given data set, clustering has led directly to scientific advances, such as the discovery of new subclasses of stars [14] and gamma-ray bursts (GRBs) [38]. All clustering algorithms seek to identify groups within a data set that reflect some observed, quantifiable structure. Clustering is traditionally an unsupervised approach to data analysis, in the sense that it operates without any direct guidance about which items should be assigned to which clusters. There has been a recent trend in the clustering literature toward supporting semisupervised or constrained

  20. The Clusters AgeS Experiment (CASE). Variable Stars in the Field of the Globular Cluster M12

    NASA Astrophysics Data System (ADS)

    Kaluzny, J.; Thompson, I. B.; Narloch, W.; Pych, W.; Rozyczka, M.

    2015-09-01

    The field of the globular cluster M12 (NGC 6218) was monitored between 1995 and 2009 in a search for variable stars. BV light curves were obtained for thirty-six periodic or likely periodic variable stars. Thirty-four of these are new detections. Among the latter we identified twenty proper-motion members of the cluster: six detached or semi-detached eclipsing binaries, five contact binaries, five SX Phe pulsators, and three yellow stragglers. Two of the eclipsing binaries are located in the turnoff region, one on the lower main sequence and the remaining three among the blue stragglers. Two contact systems are blue stragglers, and the remaining three reside in the turnoff region. In the blue straggler region a total of 103 objects were found, of which 42 are proper motion members of M12, and another four are field stars. 55 of the remaining objects are located within two core radii from the center of the cluster, and as such they are likely genuine blue stragglers. We also report the discoveries of a radial color gradient of M12, and the shortest period among contact systems in globular clusters in general.

  1. Visualizing statistical significance of disease clusters using cartograms.

    PubMed

    Kronenfeld, Barry J; Wong, David W S

    2017-05-15

    Health officials and epidemiological researchers often use maps of disease rates to identify potential disease clusters. Because these maps exaggerate the prominence of low-density districts and hide potential clusters in urban (high-density) areas, many researchers have used density-equalizing maps (cartograms) as a basis for epidemiological mapping. However, we do not have existing guidelines for visual assessment of statistical uncertainty. To address this shortcoming, we develop techniques for visual determination of statistical significance of clusters spanning one or more districts on a cartogram. We developed the techniques within a geovisual analytics framework that does not rely on automated significance testing, and can therefore facilitate visual analysis to detect clusters that automated techniques might miss. On a cartogram of the at-risk population, the statistical significance of a disease cluster is determinate from the rate, area and shape of the cluster under standard hypothesis testing scenarios. We develop formulae to determine, for a given rate, the area required for statistical significance of a priori and a posteriori designated regions under certain test assumptions. Uniquely, our approach enables dynamic inference of aggregate regions formed by combining individual districts. The method is implemented in interactive tools that provide choropleth mapping, automated legend construction and dynamic search tools to facilitate cluster detection and assessment of the validity of tested assumptions. A case study of leukemia incidence analysis in California demonstrates the ability to visually distinguish between statistically significant and insignificant regions. The proposed geovisual analytics approach enables intuitive visual assessment of statistical significance of arbitrarily defined regions on a cartogram. Our research prompts a broader discussion of the role of geovisual exploratory analyses in disease mapping and the appropriate

  2. A Commodity Computing Cluster

    NASA Astrophysics Data System (ADS)

    Teuben, P. J.; Wolfire, M. G.; Pound, M. W.; Mundy, L. G.

    We have assembled a cluster of Intel-Pentium based PCs running Linux to compute a large set of Photodissociation Region (PDR) and Dust Continuum models. For various reasons the cluster is heterogeneous, currently ranging from a single Pentium-II 333 MHz to dual Pentium-III 450 MHz CPU machines. Although this will be sufficient for our ``embarrassingly parallelizable problem'' it may present some challenges for as yet unplanned future use. In addition the cluster was used to construct a MIRIAD benchmark, and compared to equivalent Ultra-Sparc based workstations. Currently the cluster consists of 8 machines, 14 CPUs, 50GB of disk-space, and a total peak speed of 5.83 GHz, or about 1.5 Gflops. The total cost of this cluster has been about $12,000, including all cabling, networking equipment, rack, and a CD-R backup system. The URL for this project is http://dustem.astro.umd.edu.

  3. A Study of Cross-linked Regions of Poly(Vinyl Alcohol) Gels by Small-Angle Neutron Scattering

    NASA Astrophysics Data System (ADS)

    Lawrence, Mathias B.; Desa, J. A. E.; Aswal, V. K.

    2011-07-01

    A poly(vinyl alcohol)-borax cross-linked hydrogel has been studied by Small Angle Neutron Scattering as a function of borax concentration in the wave-vector transfer (Q) range of 0.017 Å-1 to 0.36 Å-1. It is found that as the concentration of borax increases, so does the intensity of scattering in this range. Beyond a borax concentration of 2 mg/ml, the increase in cross-linked PVA chains leads to cross-linked units larger than 150 Å as evidenced by a reduction in intensity in the lower Q region.

  4. Water cluster fragmentation probed by pickup experiments

    NASA Astrophysics Data System (ADS)

    Huang, Chuanfu; Kresin, Vitaly V.; Pysanenko, Andriy; Fárník, Michal

    2016-09-01

    Electron ionization is a common tool for the mass spectrometry of atomic and molecular clusters. Any cluster can be ionized efficiently by sufficiently energetic electrons, but concomitant fragmentation can seriously obstruct the goal of size-resolved detection. We present a new general method to assess the original neutral population of the cluster beam. Clusters undergo a sticking collision with a molecule from a crossed beam, and the velocities of neat and doped cluster ion peaks are measured and compared. By making use of longitudinal momentum conservation, one can reconstruct the sizes of the neutral precursors. Here this method is applied to H2O and D2O clusters in the detected ion size range of 3-10. It is found that water clusters do fragment significantly upon electron impact: the deduced neutral precursor size is ˜3-5 times larger than the observed cluster ions. This conclusion agrees with beam size characterization by another experimental technique: photoionization after Na-doping. Abundant post-ionization fragmentation of water clusters must therefore be an important factor in the interpretation of experimental data; interestingly, there is at present no detailed microscopic understanding of the underlying fragmentation dynamics.

  5. The globular cluster system of NGC 1316. IV. Nature of the star cluster complex SH2

    NASA Astrophysics Data System (ADS)

    Richtler, T.; Husemann, B.; Hilker, M.; Puzia, T. H.; Bresolin, F.; Gómez, M.

    2017-05-01

    Context. The light of the merger remnant NGC 1316 (Fornax A) is dominated by old and intermediate-age stars. The only sign of current star formation in this big galaxy is the Hii region SH2, an isolated star cluster complex with a ring-like morphology and an estimated age of 0.1 Gyr at a galactocentric distance of about 35 kpc. A nearby intermediate-age globular cluster, surrounded by weak line emission and a few more young star clusters, is kinematically associated. The origin of this complex is enigmatic. Aims: We want to investigate the nature of this star cluster complex. The nebular emission lines permit a metallicity determination which can discriminate between a dwarf galaxy or other possible precursors. Methods: We used the Integral Field Unit (IFU) of the VIMOS instrument at the Very Large Telescope of the European Southern Observatory in high dispersion mode to study the morphology, kinematics, and metallicity employing line maps, velocity maps, and line diagnostics of a few characteristic spectra. Results: The line ratios of different spectra vary, indicating highly structured Hii regions, but define a locus of uniform metallicity. The strong-line diagnostic diagrams and empirical calibrations point to a nearly solar or even super-solar oxygen abundance. The velocity dispersion of the gas is highest in the region offset from the bright clusters. Star formation may be active on a low level. There is evidence for a large-scale disk-like structure in the region of SH2, which would make the similar radial velocity of the nearby globular cluster easier to understand. Conclusions: The high metallicity does not fit to a dwarf galaxy as progenitor. We favour the scenario of a free-floating gaseous complex having its origin in the merger 2 Gyr ago. Over a long period the densities increased secularly until finally the threshold for star formation was reached. SH2 illustrates how massive star clusters can form outside starbursts and without a considerable field

  6. Interhemispheric currents in the ring current region as seen by the Cluster spacecraft

    NASA Astrophysics Data System (ADS)

    Tenfjord, P.; Ostgaard, N.; Haaland, S.; Laundal, K.; Reistad, J. P.

    2013-12-01

    The existence of interhemispheric currents has been predicted by several authors, but their extent in the ring current has to our knowledge never been studied systematically by using in-situ measurements. These currents have been suggested to be associated with observed asymmetries of the aurora. We perform a statistical study of current density and direction during ring current crossings using the Cluster spacecraft. We analyse the extent of the interhemispheric field aligned currents for a wide range of solar wind conditions. Direct estimations of equatorial current direction and density are achieved through the curlometer technique. The curlometer technique is based on Ampere's law and requires magnetic field measurements from all four spacecrafts. The use of this method requires careful study of factors that limit the accuracy, such as tetrahedron shape and configuration. This significantly limits our dataset, but is a necessity for accurate current calculations. Our goal is to statistically investigate the occurrence of interhemispheric currents, and determine if there are parameters or magnetospheric states on which the current magnitude and directions depend upon.

  7. Images in the rocket ultraviolet - Young clusters in H II regions of M83

    NASA Technical Reports Server (NTRS)

    Bohlin, Ralph C.; Cornett, Robert H.; Hill, Jesse K.; Stecher, Theodore P.

    1990-01-01

    UV images of M83 at 1540 and 2360 A reveal 18 compact sources that are associated with H II regions. E(B - V) values were estimated individually from the observed UV and optical colors and the Galactic UV extinction curve, using theoretical flux distributions. The dereddened colors are consistent with ages up to 3 x 10 to the 6th yr. A maximum possible age of 6.5 x 10 to the 6th yr is obtained assuming foreground reddening only. The distribution of observed colors is consistent with the Galactic reddening curve but not with enhanced far-UV extinction, as in the LMC 30 Dor curve. The H-alpha fluxes suggest either that dust within the H II regions absorbs up to 70 percent of the Lyman continuum radiation or that a similar fraction of the H-alpha flux is below the surface brightness detection limit. Cluster mass estimates depend on the range of stellar masses present but are probably in the range 10,000-100,000 solar masses.

  8. Dengue occurrence relations and serology: cross-sectional analysis of results from the Guerrero State, Mexico, baseline for a cluster-randomised controlled trial of community mobilisation for dengue prevention.

    PubMed

    Nava-Aguilera, Elizabeth; Morales-Pérez, Arcadio; Balanzar-Martínez, Alejandro; Rodríguez-Ramírez, Ofelia; Jiménez-Alejo, Abel; Flores-Moreno, Miguel; Gasga-Salinas, David; Legorreta-Soberanis, José; Paredes-Solís, Sergio; Morales-Nava, Pedro Antonio; de Lourdes Soto-Ríos, María; Ledogar, Robert J; Coloma, Joséfina; Harris, Eva; Andersson, Neil

    2017-05-30

    The Mexican arm of the Camino Verde trial of community mobilisation for dengue prevention covered three coastal regions of Guerrero state: Acapulco, Costa Grande and Costa Chica. A baseline cross-sectional survey provided data for community mobilisation and for adapting the intervention design to concrete conditions in the intervention areas. Trained field teams constructed community profiles in randomly selected clusters, based on observation and key informant interviews. In each household they carried out an entomological inspection of water containers, collected information on socio-demographic variables and cases of dengue illness among household members in the last year, and gathered paired saliva samples from children aged 3-9 years, which were subjected to ELISA testing to detect recent dengue infection. We examined associations with dengue illness and recent dengue infection in bivariate and then multivariate analysis. In 70/90 clusters, key informants were unable to identify any organized community groups. Some 1.9% (1029/55,723) of the household population reported dengue illness in the past year, with a higher rate in Acapulco region. Among children 3-9 years old, 6.1% (392/6382) had serological evidence of recent dengue infection. In all three regions, household use of anti-mosquito products, household heads working, and households having less than 5 members were associated with self-reported dengue illness. In Acapulco region, people aged less than 25 years, those with a more educated household head and those from urban sites were also more likely to report dengue illness, while in Costa Chica and Costa Grande, females were more likely to report dengue illness. Among children aged 3-9 years, those aged 3-4 years and those living in Acapulco were more likely to have evidence of recent dengue infection. The evidence from the baseline survey provided important support for the design and implementation of the trial intervention. The weakness of

  9. From Head to Sword: The Clustering Properties of Stars in Orion

    NASA Astrophysics Data System (ADS)

    Gomez, Mercedes; Lada, Charles J.

    1998-04-01

    We investigate the structure in the spatial distributions of optically selected samples of young stars in the Head (lambda Orionis) and in the Sword (Orion A) regions of the constellation of Orion with the aid of stellar surface density maps and the two-point angular correlation function. The distributions of young stars in both regions are found to be nonrandom and highly clustered. Stellar surface density maps reveal three distinct clusters in the lambda Ori region. The two-point correlation function displays significant features at angular scales that correspond to the radii and separations of the three clusters identified in the surface density maps. Most young stars in the lambda Ori region (~80%) are presently found within these three clusters, consistent with the idea that the majority of young stars in this region were formed in dense protostellar clusters that have significantly expanded since their formation. Over a scale of ~0.05d-0.5d the correlation function is well described by a single power law that increases smoothly with decreasing angular scale. This suggests that, within the clusters, the stars either are themselves hierarchically clustered or have a volume density distribution that falls steeply with radius. The relative lack of Hα emission-line stars in the one cluster in this region that contains OB stars suggests a timescale for emission-line activity of less than 4 Myr around late-type stars in the cluster and may indicate that the lifetimes of protoplanetary disks around young stellar objects are reduced in clusters containing O stars. The spatial distribution of young stars in the Orion A region is considerably more complex. The angular correlation function of the OB stars (which are mostly foreground to the Orion A molecular cloud) is very similar to that of the Hα stars (which are located mostly within the molecular cloud) and significantly different from that of the young stars in the lambda Ori region. This suggests that, although

  10. Vacuum ultraviolet imagery of the Virgo Cluster region. II - Total far-ultraviolet flux of galaxies

    NASA Astrophysics Data System (ADS)

    Kodaira, K.; Watanabe, T.; Onaka, T.; Tanaka, W.

    1990-11-01

    The total flux in the far-ultraviolet region around 150 nm was measured for more than 40 galaxies in the central region of the Virgo Cluster, using two imaging telescopes on board a sounding rocket. The observed far-ultraviolet flux shows positive correlations with the H I 21 cm flux and the far-infrared flux for spiral galaxies, and with the X-ray flux and the radio continuum flux for elliptical galaxies. The former correlations of spiral galaxies are interpreted in terms of star formation activity, which indicates substantial depletion in the Virgo galaxies in accordance with the H I stripping. The latter correlations of elliptical galaxies indicate possible far-ultraviolet sources of young population, in addition to evolved hot stars. Far-ultraviolet fluxes from two dwarf elliptical galaxies were obtained tentatively, indicating star formation activity in elliptical galaxies. A high-resolution UV imagery by HST would be effective to distinguish the young population and the old population in elliptical galaxies.

  11. Dwarfs in Coma Cluster

    NASA Technical Reports Server (NTRS)

    2007-01-01

    [figure removed for brevity, see original site] Click on image for larger poster version

    This false-color mosaic of the central region of the Coma cluster combines infrared and visible-light images to reveal thousands of faint objects (green). Follow-up observations showed that many of these objects, which appear here as faint green smudges, are dwarf galaxies belonging to the cluster. Two large elliptical galaxies, NGC 4889 and NGC 4874, dominate the cluster's center. The mosaic combines visible-light data from the Sloan Digital Sky Survey (color coded blue) with long- and short-wavelength infrared views (red and green, respectively) from NASA's Spitzer Space Telescope.

  12. Somatotyping using 3D anthropometry: a cluster analysis.

    PubMed

    Olds, Tim; Daniell, Nathan; Petkov, John; David Stewart, Arthur

    2013-01-01

    Somatotyping is the quantification of human body shape, independent of body size. Hitherto, somatotyping (including the most popular method, the Heath-Carter system) has been based on subjective visual ratings, sometimes supported by surface anthropometry. This study used data derived from three-dimensional (3D) whole-body scans as inputs for cluster analysis to objectively derive clusters of similar body shapes. Twenty-nine dimensions normalised for body size were measured on a purposive sample of 301 adults aged 17-56 years who had been scanned using a Vitus Smart laser scanner. K-means Cluster Analysis with v-fold cross-validation was used to determine shape clusters. Three male and three female clusters emerged, and were visualised using those scans closest to the cluster centroid and a caricature defined by doubling the difference between the average scan and the cluster centroid. The male clusters were decidedly endomorphic (high fatness), ectomorphic (high linearity), and endo-mesomorphic (a mixture of fatness and muscularity). The female clusters were clearly endomorphic, ectomorphic, and the ecto-mesomorphic (a mixture of linearity and muscularity). An objective shape quantification procedure combining 3D scanning and cluster analysis yielded shape clusters strikingly similar to traditional somatotyping.

  13. Analyzing Flood Vulnerability Due to Sea Level Rise Using K-Means Clustering: Implications for Regional Flood Mitigation Planning

    NASA Astrophysics Data System (ADS)

    Hummel, M.; Wood, N. J.; Stacey, M. T.; Schweikert, A.; Barnard, P.; Erikson, L. H.

    2016-12-01

    The threat of tidal flooding in coastal regions is exacerbated by sea level rise (SLR), which can lead to more frequent and persistent nuisance flooding and permanent inundation of low-lying areas. When coupled with extreme storm events, SLR also increases the extent and depth of flooding due to storm surges. To mitigate these impacts, bayfront communities are considering a variety of options for shoreline protection, including restoration of natural features such as wetlands and hardening of the shoreline using levees and sea walls. These shoreline modifications can produce changes in the tidal dynamics in a basin, either by increasing dissipation of tidal energy or enhancing tidal amplification [1]. As a result, actions taken by individual communities not only impact local inundation, but can also have implications for flooding on a regional scale. However, regional collaboration is lacking in flood mitigation planning, which is often done on a community-by-community basis. This can lead to redundancy in planning efforts and can also have adverse effects on communities that are not included in discussions about shoreline infrastructure improvements. Using flooding extent outputs from a hydrodynamic model of San Francisco Bay, we performed a K-means clustering analysis to identify similarities between 65 bayfront communities in terms of the spatial, demographic, and economic characteristics of their vulnerable assets for a suite of SLR and storm scenarios. Our clustering analysis identifies communities with similar vulnerabilities and allows for more effective collaboration and decision-making at a regional level by encouraging comparable communities to work together and pool resources to find effective adaptation strategies as flooding becomes more frequent and severe. [1] Holleman RC, Stacey MT (2014) Coupling of sea level rise, tidal amplification, and inundation. Journal of Physical Oceanography 44:1439-1455.

  14. Galaxy properties in clusters. II. Backsplash galaxies

    NASA Astrophysics Data System (ADS)

    Muriel, H.; Coenda, V.

    2014-04-01

    Aims: We explore the properties of galaxies on the outskirts of clusters and their dependence on recent dynamical history in order to understand the real impact that the cluster core has on the evolution of galaxies. Methods: We analyse the properties of more than 1000 galaxies brighter than M0.1r = - 19.6 on the outskirts of 90 clusters (1 < r/rvir < 2) in the redshift range 0.05 < z < 0.10. Using the line of sight velocity of galaxies relative to the cluster's mean, we selected low and high velocity subsamples. Theoretical predictions indicate that a significant fraction of the first subsample should be backsplash galaxies, that is, objects that have already orbited near the cluster centre. A significant proportion of the sample of high relative velocity (HV) galaxies seems to be composed of infalling objects. Results: Our results suggest that, at fixed stellar mass, late-type galaxies in the low-velocity (LV) sample are systematically older, redder, and have formed fewer stars during the last 3 Gyrs than galaxies in the HV sample. This result is consistent with models that assume that the central regions of clusters are effective in quenching the star formation by means of processes such as ram pressure stripping or strangulation. At fixed stellar mass, LV galaxies show some evidence of having higher surface brightness and smaller size than HV galaxies. These results are consistent with the scenario where galaxies that have orbited the central regions of clusters are more likely to suffer tidal effects, producing loss of mass as well as a re-distribution of matter towards more compact configurations. Finally, we found a higher fraction of ET galaxies in the LV sample, supporting the idea that the central region of clusters of galaxies may contribute to the transformation of morphological types towards earlier types.

  15. Search for OB stars running away from young star clusters. II. The NGC 6357 star-forming region

    NASA Astrophysics Data System (ADS)

    Gvaramadze, V. V.; Kniazev, A. Y.; Kroupa, P.; Oh, S.

    2011-11-01

    Dynamical few-body encounters in the dense cores of young massive star clusters are responsible for the loss of a significant fraction of their massive stellar content. Some of the escaping (runaway) stars move through the ambient medium supersonically and can be revealed via detection of their bow shocks (visible in the infrared, optical or radio). In this paper, which is the second of a series of papers devoted to the search for OB stars running away from young ( ≲ several Myr) Galactic clusters and OB associations, we present the results of the search for bow shocks around the star-forming region NGC 6357. Using the archival data of the Midcourse Space Experiment (MSX) satellite and the Spitzer Space Telescope, and the preliminary data release of the Wide-Field Infrared Survey Explorer (WISE), we discovered seven bow shocks, whose geometry is consistent with the possibility that they are generated by stars expelled from the young (~1-2 Myr) star clusters, Pismis 24 and AH03 J1725-34.4, associated with NGC 6357. Two of the seven bow shocks are driven by the already known OB stars, HD 319881 and [N78] 34. Follow-up spectroscopy of three other bow-shock-producing stars showed that they are massive (O-type) stars as well, while the 2MASS photometry of the remaining two stars suggests that they could be B0 V stars, provided that both are located at the same distance as NGC 6357. Detection of numerous massive stars ejected from the very young clusters is consistent with the theoretical expectation that star clusters can effectively lose massive stars at the very beginning of their dynamical evolution (long before the second mechanism for production of runaway stars, based on a supernova explosion in a massive tight binary system, begins to operate) and lends strong support to the idea that probably all field OB stars have been dynamically ejected from their birth clusters. A by-product of our search for bow shocks around NGC 6357 is the detection of three circular

  16. Peculiar motions of galaxy clusters in the regions of the Corona Borealis, Bootes, Z 5029/A 1424, A 1190, A 1750/A 1809 superclusters of galaxies

    NASA Astrophysics Data System (ADS)

    Kopylova, F. G.; Kopylov, A. I.

    2017-10-01

    We present results of the study of peculiar motions of 57 clusters and groups of galaxies in the regions of the Corona Borealis (CrB), Bootes (Boo), Z5029/A1424, A1190, A1750/A1809 superclusters of galaxies and the galaxy clusters located beyond massive structures (0.05 < z < 0.10). Using the SDSS (Data Release 8) data, a sample of early-type galaxies was compiled in the systems under study, their fundamental planes were built, and relative distances and peculiar velocities were determined. Within the galaxy superclusters, significant peculiar motions along the line of sight are observed with rms deviations of 652 ± 50 kms-1—in CrB, 757 ± 70 kms-1—in Boo. In the most massive A2065 cluster in the CrB supercluster, no peculiar velocity was found. Peculiar motions of the other galaxy clusters can be caused by their gravitational interaction both with A2065 and with the A2142 supercluster. It has been found that there are two superclusters projected onto each other in the region of the Bootes supercluster with a radial velocity difference of about 4000 kms-1. In the Z 5029/A1424 supercluster near the rich Z5029 cluster, the most considerable peculiar motions with a rms deviations of 1366 ± 170 kms-1 are observed. The rms deviations of peculiar velocities of 20 clusters that do not belong to large-scale structures is equal to 0 ± 20 kms-1. The whole sample of the clusters under study has the mean peculiar velocity equal to 83 ± 130 kms-1 relative to the cosmic microwave background.

  17. Disruption of SLP-76 interaction with Gads inhibits dynamic clustering of SLP-76 and FcepsilonRI signaling in mast cells.

    PubMed

    Silverman, Michael A; Shoag, Jonathan; Wu, Jennifer; Koretzky, Gary A

    2006-03-01

    We developed a confocal real-time imaging approach that allows direct observation of the subcellular localization pattern of proteins involved in proximal FcepsilonRI signaling in RBL cells and primary bone marrow-derived mast cells. The adaptor protein Src homology 2 (SH2) domain-containing leukocyte phosphoprotein of 76 kDa (SLP-76) is critical for FcepsilonRI-induced calcium flux, degranulation, and cytokine secretion. In this study, we imaged SLP-76 and found it in the cytosol of unstimulated cells. Upon FcepsilonRI cross-linking, SLP-76 translocates to the cell membrane, forming clusters that colocalize with the FcepsilonRI, the tyrosine kinase Syk, the adaptor LAT, and phosphotyrosine. The disruption of the SLP-76 interaction with its constitutive binding partner, Gads, through the mutation of SLP-76 or the expression of the Gads-binding region of SLP-76, inhibits the translocation and clustering of SLP-76, suggesting that the interaction of SLP-76 with Gads is critical for appropriate subcellular localization of SLP-76. We further demonstrated that the expression of the Gads-binding region of SLP-76 in bone marrow-derived mast cells inhibits FcepsilonRI-induced calcium flux, degranulation, and cytokine secretion. These studies revealed, for the first time, that SLP-76 forms signaling clusters following FcepsilonRI stimulation and demonstrated that the Gads-binding region of SLP-76 regulates clustering of SLP-76 and FcepsilonRI-induced mast cell responses.

  18. Development and Structure of Winter Monsoon Cloud Clusters On 10 December 1978.

    NASA Astrophysics Data System (ADS)

    Churchill, Dean D.; Houze, Robert A., Jr.

    1984-03-01

    Data from the Winter Monsoon Experiment (WMONEX) are used to study cloud clusters that occurred over the South China Sea on 10 December 1978. These clusters underwent life cycles in which they began as groups of intense convective cells and then developed into mesoscale systems consisting partly of convective cells and partly of stratiform precipitation. In the cellular regions of clusters, ice particle concentrations (at the 8 km, or 17°C, level) were found to be of the order of hundreds per liter, local convective updrafts of 4-17 m s1 were observed, and the dominant ice-particle growth mechanism appeared to be riming. In the stratiform regions of clusters, the ice particles appeared to grow by vapor deposition and aggregation and weaker but more widespread mesoscale updraft motion was indicated at mid to upper levels by the observed ice-crystal structures, while unsaturated mesoscale downdraft motion was indicated at mid to lower levels by sounding data. The ice-particle concentrations at 8 km in stratiform regions were one to two orders of magnitude lower than in the convective regions; in areas of weaker stratiform precipitation the concentrations were 1-10 per liter, while in areas of stronger stratiform precipitation they were 20-70 per liter. Substructure within the stratiform regions was indicated by variations in observed ice-crystal habits over horizontal distances of 10-100 km.The dominant cluster observed on this day was initiated when a group of convective cells formed just off the Borneo coast, apparently in response to land-breeze convergence. During the mature stage of this cluster, the stratiform rain area became nearly surrounded by a broken line of convective cells of various intensity. The greatest concentration of intense cores was maintained in a generally stationary region on the southeast side of the cluster where the land-breeze convergence was located, while convection on the northwest side of the cluster propagated out to sea. The

  19. Regional specific groundwater arsenic levels and neuropsychological functioning: a cross-sectional study.

    PubMed

    Edwards, Melissa; Johnson, Leigh; Mauer, Cortney; Barber, Robert; Hall, James; O'Bryant, Sid

    2014-01-01

    The purpose of the study was to examine the link between geographic information system (GIS)-estimated regional specific groundwater levels and neuropsychological functioning in a sample of individuals with and without cognitive impairment. This cross-sectional study design analyzed data from 1390 participants (733 Alzheimer's disease, 127 Mild Cognitive Impairment, and 530 with normal cognition) enrolled in the Texas Alzheimer's Research and Care Consortium. GISs analyses were used to estimate regional specific groundwater arsenic concentrations using the Environmental Systems Research Institute and arsenic concentrations from the Texas Water Development Board. In the full cohort, regional specific arsenic concentrations were positively associated with language abilities (p = 0.008), but associated with poorer verbal memory, immediate (p = 0.008), and delayed (p < 0.001), as well as poorer visual memory, immediate (p = 0.02), and delayed (p < 0.001). The findings varied by diagnostic category with arsenic being related with cognition most prominently among mild cognitive impairment cases. Overall, estimated regional specific groundwater arsenic levels were negatively associated with neuropsychological performance.

  20. Regional specific groundwater arsenic levels and neuropsychological functioning: a cross-sectional study

    PubMed Central

    Edwards, Melissa; Johnson, Leigh; Mauer, Cortney; Barber, Robert; Hall, James; O'Bryant, Sid

    2014-01-01

    Background The purpose of the study was to examine the link between GIS-estimated regional specific groundwater levels and neuropsychological functioning in a sample of individuals with and without cognitive impairment. Methods This cross-sectional study design analyzed data from 1390 participants (733 Alzheimer's disease, 127 Mild Cognitive Impairment, and 530 with normal cognition) enrolled in the Texas Alzheimer's Research and Care Consortium. Geographic information systems analyses were used to estimate regional specific groundwater arsenic concentrations using the Environmental Systems Research Institute and arsenic concentrations from the Texas Water Development Board. Results In the full cohort, regional specific arsenic concentrations were positively associated with language abilities (p=0.008), but associated with poorer verbal memory, immediate (p=0.008) and delayed (p<0.001) as well as poorer visual memory, immediate (p=0.02) and delayed (p<0.001). The findings varied by diagnostic category with arsenic being related with cognition most prominently among MCI cases. Conclusions Overall, estimated regional specific groundwater arsenic levels were negatively associated with neuropsychological performance. PMID:24506178

  1. The Nature and Origin of UCDs in the Coma Cluster

    NASA Astrophysics Data System (ADS)

    Chiboucas, Kristin; Tully, R. Brent; Madrid, Juan; Phillipps, Steven; Carter, David; Peng, Eric

    2018-01-01

    UCDs are super massive star clusters found largely in dense regions but have also been found around individual galaxies and in smaller groups. Their origin is still under debate but currently favored scenarios include formation as giant star clusters, either as the brightest globular clusters or through mergers of super star clusters, themselves formed during major galaxy mergers, or as remnant nuclei from tidal stripping of nucleated dwarf ellipticals. Establishing the nature of these enigmatic objects has important implications for our understanding of star formation, star cluster formation, the missing satellite problem, and galaxy evolution. We are attempting to disentangle these competing formation scenarios with a large survey of UCDs in the Coma cluster. Using ACS two-passband imaging from the HST/ACS Coma Cluster Treasury Survey, we are using colors and sizes to identify the UCD cluster members. With a large size limited sample of the UCD population within the core region of the Coma cluster, we are investigating the population size, properties, and spatial distribution, and comparing that with the Coma globular cluster and nuclear star cluster populations to discriminate between the threshing and globular cluster scenarios. In previous work, we had found a possible correlation of UCD colors with host galaxy and a possible excess of UCDs around a non-central giant galaxy with an unusually large globular cluster population, both suggestive of a globular cluster origin. With a larger sample size and additional imaging fields that encompass the regions around these giant galaxies, we have found that the color correlation with host persists and the giant galaxy with unusually large globular cluster population does appear to host a large UCD population as well. We present the current status of the survey.

  2. A cross-sectional, randomized cluster sample survey of household vulnerability to extreme heat among slum dwellers in ahmedabad, india.

    PubMed

    Tran, Kathy V; Azhar, Gulrez S; Nair, Rajesh; Knowlton, Kim; Jaiswal, Anjali; Sheffield, Perry; Mavalankar, Dileep; Hess, Jeremy

    2013-06-18

    Extreme heat is a significant public health concern in India; extreme heat hazards are projected to increase in frequency and severity with climate change. Few of the factors driving population heat vulnerability are documented, though poverty is a presumed risk factor. To facilitate public health preparedness, an assessment of factors affecting vulnerability among slum dwellers was conducted in summer 2011 in Ahmedabad, Gujarat, India. Indicators of heat exposure, susceptibility to heat illness, and adaptive capacity, all of which feed into heat vulnerability, was assessed through a cross-sectional household survey using randomized multistage cluster sampling. Associations between heat-related morbidity and vulnerability factors were identified using multivariate logistic regression with generalized estimating equations to account for clustering effects. Age, preexisting medical conditions, work location, and access to health information and resources were associated with self-reported heat illness. Several of these variables were unique to this study. As sociodemographics, occupational heat exposure, and access to resources were shown to increase vulnerability, future interventions (e.g., health education) might target specific populations among Ahmedabad urban slum dwellers to reduce vulnerability to extreme heat. Surveillance and evaluations of future interventions may also be worthwhile.

  3. A black hole in a globular cluster.

    PubMed

    Maccarone, Thomas J; Kundu, Arunav; Zepf, Stephen E; Rhode, Katherine L

    2007-01-11

    Globular star clusters contain thousands to millions of old stars packed within a region only tens of light years across. Their high stellar densities make it very probable that their member stars will interact or collide. There has accordingly been considerable debate about whether black holes should exist in these star clusters. Some theoretical work suggests that dynamical processes in the densest inner regions of globular clusters may lead to the formation of black holes of approximately 1,000 solar masses. Other numerical simulations instead predict that stellar interactions will eject most or all of the black holes that form in globular clusters. Here we report the X-ray signature of an accreting black hole in a globular cluster associated with the giant elliptical galaxy NGC 4472 (in the Virgo cluster). This object has an X-ray luminosity of about 4 x 10(39) erg s(-1), which rules out any object other than a black hole in such an old stellar population. The X-ray luminosity varies by a factor of seven in a few hours, which excludes the possibility that the object is several neutron stars superposed.

  4. A perfect starburst cluster made in one go: The NGC 3603 young cluster

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Banerjee, Sambaran; Kroupa, Pavel

    2014-06-01

    Understanding how distinct, near-spherical gas-free clusters of very young, massive stars shape out of vast, complex clouds of molecular hydrogen is one of the biggest challenges in astrophysics. A popular thought dictates that a single gas cloud fragments into many newborn stars which, in turn, energize and rapidly expel the residual gas to form a gas-free cluster. This study demonstrates that the above classical paradigm remarkably reproduces the well-observed central, young cluster (HD 97950) of the Galactic NGC 3603 star-forming region, in particular, its shape, internal motion, and mass distribution of stars naturally and consistently follow from a single modelmore » calculation. Remarkably, the same parameters (star formation efficiency, gas expulsion timescale, and delay) reproduce HD 97950, as were found to reproduce the Orion Nebula Cluster, Pleiades, and R136. The present results therefore provide intriguing evidence of formation of star clusters through single-starburst events followed by significant residual gas expulsion.« less

  5. The SAMI Galaxy Survey: the cluster redshift survey, target selection and cluster properties

    NASA Astrophysics Data System (ADS)

    Owers, M. S.; Allen, J. T.; Baldry, I.; Bryant, J. J.; Cecil, G. N.; Cortese, L.; Croom, S. M.; Driver, S. P.; Fogarty, L. M. R.; Green, A. W.; Helmich, E.; de Jong, J. T. A.; Kuijken, K.; Mahajan, S.; McFarland, J.; Pracy, M. B.; Robotham, A. G. S.; Sikkema, G.; Sweet, S.; Taylor, E. N.; Verdoes Kleijn, G.; Bauer, A. E.; Bland-Hawthorn, J.; Brough, S.; Colless, M.; Couch, W. J.; Davies, R. L.; Drinkwater, M. J.; Goodwin, M.; Hopkins, A. M.; Konstantopoulos, I. S.; Foster, C.; Lawrence, J. S.; Lorente, N. P. F.; Medling, A. M.; Metcalfe, N.; Richards, S. N.; van de Sande, J.; Scott, N.; Shanks, T.; Sharp, R.; Thomas, A. D.; Tonini, C.

    2017-06-01

    We describe the selection of galaxies targeted in eight low-redshift clusters (APMCC0917, A168, A4038, EDCC442, A3880, A2399, A119 and A85; 0.029 < z < 0.058) as part of the Sydney-AAO Multi-Object Integral field spectrograph Galaxy Survey (SAMI-GS). We have conducted a redshift survey of these clusters using the AAOmega multi-object spectrograph on the 3.9-m Anglo-Australian Telescope. The redshift survey is used to determine cluster membership and to characterize the dynamical properties of the clusters. In combination with existing data, the survey resulted in 21 257 reliable redshift measurements and 2899 confirmed cluster member galaxies. Our redshift catalogue has a high spectroscopic completeness (˜94 per cent) for rpetro ≤ 19.4 and cluster-centric distances R < 2R200. We use the confirmed cluster member positions and redshifts to determine cluster velocity dispersion, R200, virial and caustic masses, as well as cluster structure. The clusters have virial masses 14.25 ≤ log(M200/M⊙) ≤ 15.19. The cluster sample exhibits a range of dynamical states, from relatively relaxed-appearing systems, to clusters with strong indications of merger-related substructure. Aperture- and point spread function matched photometry are derived from Sloan Digital Sky Survey and VLT Survey Telescope/ATLAS imaging and used to estimate stellar masses. These estimates, in combination with the redshifts, are used to define the input target catalogue for the cluster portion of the SAMI-GS. The primary SAMI-GS cluster targets have R cluster regions.

  6. Radio supernovae and super star clusters in the circumnuclear region of NGC 1365

    NASA Astrophysics Data System (ADS)

    Lindblad, P. O.; Kristen, H.

    Groundbased optical and VLA observations have shown that the nucleus of the barred Seyfert 1 galaxy NGC 1365 is surrounded by a number of star forming regions, or "hot spots", as well as a number of resolved and unresolved continuum radio sources. HST/FOC observations reveal that the nucleus is surrounded by a ring of very compact unresolved sources of the kind that have been discovered in a number of other galaxies, and that have been assumed to be very compact young globular star clusters. The hot spots are resolved into groups of such compact sources. VLA observations at lambda = 2 cm, where the resolution approaches that of HST, reveals that the brightest unresolved radio source at 2 cm, which has been assumed to be a radio supernova, coincides with one of the compact HST sources. The implications of this will be discussed.

  7. Bottomside sinusoidal irregularities in the equatorial F region. II - Cross-correlation and spectral analysis

    NASA Technical Reports Server (NTRS)

    Cragin, B. L.; Hanson, W. B.; Mcclure, J. P.; Valladares, C. E.

    1985-01-01

    Equatorial bottomside sinusoidal (BSS) irregularities have been studied by applying techniques of cross-correlation and spectral analysis to the Atmosphere Explorer data set. The phase of the cross-correlations of the plasma number density is discussed and the two drift velocity components observed using the retarding potential analyzer and ion drift meter on the satellite are discussed. Morphology is addressed, presenting the geographical distributions of the occurrence of BSS events for the equinoxes and solstices. Physical processes including the ion Larmor flux, interhemispheric plasma flows, and variations in the lower F region Pedersen conductivity are invoked to explain the findings.

  8. The Difference Between Clusters and Groups: A Journey from Cluster Cores to Their Outskirts and Beyond

    NASA Astrophysics Data System (ADS)

    Bower, Richard G.; Balogh, Michael L.

    In this review, we take the reader on a journey. We start by looking at the properties of galaxies in the cores of rich clusters. We have focused on the overall picture: star formation in clusters is strongly suppressed relative to field galaxies at the same redshift. We will argue that the increasing activity and blue populations of clusters with redshift results from a greater level of activity in field galaxies rather than a change in the transformation imposed by the cluster environment. With this in mind, we travel out from the cluster, focusing first on the properties of galaxies in the outskirts of clusters and then on galaxies in isolated groups. At low redshift, we are able to efficiently probe these environments using the Sloan Digital Sky Survey and 2dF redshift surveys. These allow an accurate comparison of galaxy star formation rates in different regions. The current results show a strong suppression of star formation above a critical threshold in local density. The threshold seems similar regardless of the overall mass of the system. At low redshift at least, only galaxies in close, isolated pairs have their star formation rate boosted above the global average. At higher redshift, work on constructing homogeneous catalogs of galaxies in groups and in the infall regions of clusters is still at an early stage. In the final section, we draw these strands together, summarizing what we can deduce about the mechanisms that transform star-forming field galaxies into their quiescent cluster counterparts. We discuss what we can learn about the impact of environment on the global star formation history of the Universe.

  9. The cluster Abell 780: an optical view

    NASA Astrophysics Data System (ADS)

    Durret, F.; Slezak, E.; Adami, C.

    2009-11-01

    Context: The Abell 780 cluster, better known as the Hydra A cluster, has been thouroughly analyzed in X-rays. However, little is known about its optical properties. Aims: We propose to derive the galaxy luminosity function (GLF) in this apparently relaxed cluster and to search for possible environmental effects by comparing the GLFs in various regions and by looking at the galaxy distribution at large scale around Abell 780. Methods: Our study is based on optical images obtained with the ESO 2.2m telescope and WFI camera in the B and R bands, covering a total region of 67.22 × 32.94 arcmin^2, or 4.235 × 2.075 Mpc2 for a cluster redshift of 0.0539. Results: In a region of 500 kpc radius around the cluster center, the GLF in the R band shows a double structure, with a broad and flat bright part and a flat faint end that can be fit by a power law with an index α ~ - 0.85 ± 0.12 in the 20.25 ≤ R ≤ 21.75 interval. If we divide this 500 kpc radius region in north+south or east+west halves, we find no clear difference between the GLFs in these smaller regions. No obvious large-scale structure is apparent within 5 Mpc from the cluster, based on galaxy redshifts and magnitudes collected from the NED database in a much larger region than that covered by our data, suggesting that there is no major infall of material in any preferential direction. However, the Serna-Gerbal method reveals a gravitationally bound structure of 27 galaxies, which includes the cD, and of a more strongly gravitationally bound structure of 14 galaxies. Conclusions: These optical results agree with the overall relaxed structure of Abell 780 previously derived from X-ray analyses. Based on observations obtained at the European Southern Observatory, program ESO 68.A-0084(A), P. I. E. Slezak. This research has made use of the NASA/IPAC Extragalactic Database (NED), which is operated by the Jet Propulsion Laboratory, California Institute of Technology, under contract with the National Aeronautics

  10. Visualization of heterogeneity and regional grading of gliomas by multiple features using magnetic resonance-based clustered images.

    PubMed

    Inano, Rika; Oishi, Naoya; Kunieda, Takeharu; Arakawa, Yoshiki; Kikuchi, Takayuki; Fukuyama, Hidenao; Miyamoto, Susumu

    2016-07-26

    Preoperative glioma grading is important for therapeutic strategies and influences prognosis. Intratumoral heterogeneity can cause an underestimation of grading because of the sampling error in biopsies. We developed a voxel-based unsupervised clustering method with multiple magnetic resonance imaging (MRI)-derived features using a self-organizing map followed by K-means. This method produced novel magnetic resonance-based clustered images (MRcIs) that enabled the visualization of glioma grades in 36 patients. The 12-class MRcIs revealed the highest classification performance for the prediction of glioma grading (area under the receiver operating characteristic curve = 0.928; 95% confidential interval = 0.920-0.936). Furthermore, we also created 12-class MRcIs in four new patients using the previous data from the 36 patients as training data and obtained tissue sections of the classes 11 and 12, which were significantly higher in high-grade gliomas (HGGs), and those of classes 4, 5 and 9, which were not significantly different between HGGs and low-grade gliomas (LGGs), according to a MRcI-based navigational system. The tissues of classes 11 and 12 showed features of malignant glioma, whereas those of classes 4, 5 and 9 showed LGGs without anaplastic features. These results suggest that the proposed voxel-based clustering method provides new insights into preoperative regional glioma grading.

  11. Evaluation of neutron total and capture cross sections on 99Tc in the unresolved resonance region

    NASA Astrophysics Data System (ADS)

    Iwamoto, Nobuyuki; Katabuchi, Tatsuya

    2017-09-01

    Long-lived fission product Technetium-99 is one of the most important radioisotopes for nuclear transmutation. The reliable nuclear data are indispensable for a wide energy range up to a few MeV, in order to develop environmental load reducing technology. The statistical analyses of resolved resonances were performed by using the truncated Porter-Thomas distribution, coupled-channels optical model, nuclear level density model and Bayes' theorem on conditional probability. The total and capture cross sections were calculated by a nuclear reaction model code CCONE. The resulting cross sections have statistical consistency between the resolved and unresolved resonance regions. The evaluated capture data reproduce those recently measured at ANNRI of J-PARC/MLF above resolved resonance region up to 800 keV.

  12. A method for automatic grain segmentation of multi-angle cross-polarized microscopic images of sandstone

    NASA Astrophysics Data System (ADS)

    Jiang, Feng; Gu, Qing; Hao, Huizhen; Li, Na; Wang, Bingqian; Hu, Xiumian

    2018-06-01

    Automatic grain segmentation of sandstone is to partition mineral grains into separate regions in the thin section, which is the first step for computer aided mineral identification and sandstone classification. The sandstone microscopic images contain a large number of mixed mineral grains where differences among adjacent grains, i.e., quartz, feldspar and lithic grains, are usually ambiguous, which make grain segmentation difficult. In this paper, we take advantage of multi-angle cross-polarized microscopic images and propose a method for grain segmentation with high accuracy. The method consists of two stages, in the first stage, we enhance the SLIC (Simple Linear Iterative Clustering) algorithm, named MSLIC, to make use of multi-angle images and segment the images as boundary adherent superpixels. In the second stage, we propose the region merging technique which combines the coarse merging and fine merging algorithms. The coarse merging merges the adjacent superpixels with less evident boundaries, and the fine merging merges the ambiguous superpixels using the spatial enhanced fuzzy clustering. Experiments are designed on 9 sets of multi-angle cross-polarized images taken from the three major types of sandstones. The results demonstrate both the effectiveness and potential of the proposed method, comparing to the available segmentation methods.

  13. Research on the Mechanism of Cross Regional Grassland Ecological Compensation

    NASA Astrophysics Data System (ADS)

    Yang, Ran; Ma, Jun

    2018-01-01

    In recent years, grassland environmental damage has become serious, and grassland resources protection task has become heavy, grassland ecological compensation has become an effective way to solve this problem; but the current grassland ecological compensation standards were low, the effect is poor. The fundamental reason is the model of administrative division destroys the integrity of grassland. Based on the analysis of the status quo of grassland compensation, this paper tries to protect the grassland integrity, breaks the administrative division restriction, implements the space regulation, constructs the framework of cross-regional grassland ecological compensation mechanism, describes its operation process. It provides new way to realize the sustainable development of the grassland environment.

  14. Regional incentives and patient cross-border mobility: evidence from the Italian experience

    PubMed Central

    Brenna, Elenka; Spandonaro, Federico

    2015-01-01

    Background: In recent years, accreditation of private hospitals followed by decentralisation of the Italian National Health Service (NHS) into 21 regional health systems has provided a good empirical ground for investigating the Tiebout principle of "voting with their feet". We examine the infra-regional trade-off between greater patient choice (due to an increase in hospital services supply) and financial equilibrium, and we relate it to the significant phenomenon of Cross-Border Mobility (CBM) between Italian regions. Focusing on the rules supervising the financial agreements between regional authorities and providers of hospital care, we find incentives for private accredited providers in attracting patient inflows. Methods: The analysis is undertaken from an institutional, regulatory and empirical perspective. We select a sample of five regions with higher positive CBM balance and we examine regional regulations governing the contractual agreements between purchasers and providers of hospital care. According to this sample, we provide a statistical analysis of CBM and apply a Regional Attraction Ability Index (RAAI), aimed at testing patient preferences for private/public accredited providers. Results: We find that this index is systematically higher for private providers, both in the case of distance/boundary patients and of excellence/general hospitals. Conclusion: Conclusions address both financial issues regarding the coverage of regional healthcare systems and equity issues on patient healthcare access. They also raise concerns on the new European Union (EU) directive inherent to patient mobility across Europe. PMID:26029895

  15. Clustering P-Wave Receiver Functions To Constrain Subsurface Seismic Structure

    NASA Astrophysics Data System (ADS)

    Chai, C.; Larmat, C. S.; Maceira, M.; Ammon, C. J.; He, R.; Zhang, H.

    2017-12-01

    The acquisition of high-quality data from permanent and temporary dense seismic networks provides the opportunity to apply statistical and machine learning techniques to a broad range of geophysical observations. Lekic and Romanowicz (2011) used clustering analysis on tomographic velocity models of the western United States to perform tectonic regionalization and the velocity-profile clusters agree well with known geomorphic provinces. A complementary and somewhat less restrictive approach is to apply cluster analysis directly to geophysical observations. In this presentation, we apply clustering analysis to teleseismic P-wave receiver functions (RFs) continuing efforts of Larmat et al. (2015) and Maceira et al. (2015). These earlier studies validated the approach with surface waves and stacked EARS RFs from the USArray stations. In this study, we experiment with both the K-means and hierarchical clustering algorithms. We also test different distance metrics defined in the vector space of RFs following Lekic and Romanowicz (2011). We cluster data from two distinct data sets. The first, corresponding to the western US, was by smoothing/interpolation of receiver-function wavefield (Chai et al. 2015). Spatial coherence and agreement with geologic region increase with this simpler, spatially smoothed set of observations. The second data set is composed of RFs for more than 800 stations of the China Digital Seismic Network (CSN). Preliminary results show a first order agreement between clusters and tectonic region and each region cluster includes a distinct Ps arrival, which probably reflects differences in crustal thickness. Regionalization remains an important step to characterize a model prior to application of full waveform and/or stochastic imaging techniques because of the computational expense of these types of studies. Machine learning techniques can provide valuable information that can be used to design and characterize formal geophysical inversion, providing

  16. Effect of tidal fields on star clusters

    NASA Technical Reports Server (NTRS)

    Chernoff, David; Weinberg, Martin

    1991-01-01

    We follow the dynamical evolution of a star cluster in a galactic tidal field using a restricted N-body code. We find large asymmetric distortions in the outer profile of the cluster in the first 10 or so crossing times as material is lost. Prograde stars escape preferentially and establish a potentially observable retrograde rotation in the halo. We present the rate of particle loss and compare with the prescription proposed by Lee and Ostriker (1987).

  17. Adaptive Scaling of Cluster Boundaries for Large-Scale Social Media Data Clustering.

    PubMed

    Meng, Lei; Tan, Ah-Hwee; Wunsch, Donald C

    2016-12-01

    The large scale and complex nature of social media data raises the need to scale clustering techniques to big data and make them capable of automatically identifying data clusters with few empirical settings. In this paper, we present our investigation and three algorithms based on the fuzzy adaptive resonance theory (Fuzzy ART) that have linear computational complexity, use a single parameter, i.e., the vigilance parameter to identify data clusters, and are robust to modest parameter settings. The contribution of this paper lies in two aspects. First, we theoretically demonstrate how complement coding, commonly known as a normalization method, changes the clustering mechanism of Fuzzy ART, and discover the vigilance region (VR) that essentially determines how a cluster in the Fuzzy ART system recognizes similar patterns in the feature space. The VR gives an intrinsic interpretation of the clustering mechanism and limitations of Fuzzy ART. Second, we introduce the idea of allowing different clusters in the Fuzzy ART system to have different vigilance levels in order to meet the diverse nature of the pattern distribution of social media data. To this end, we propose three vigilance adaptation methods, namely, the activation maximization (AM) rule, the confliction minimization (CM) rule, and the hybrid integration (HI) rule. With an initial vigilance value, the resulting clustering algorithms, namely, the AM-ART, CM-ART, and HI-ART, can automatically adapt the vigilance values of all clusters during the learning epochs in order to produce better cluster boundaries. Experiments on four social media data sets show that AM-ART, CM-ART, and HI-ART are more robust than Fuzzy ART to the initial vigilance value, and they usually achieve better or comparable performance and much faster speed than the state-of-the-art clustering algorithms that also do not require a predefined number of clusters.

  18. A screened independent atom model for the description of ion collisions from atomic and molecular clusters

    NASA Astrophysics Data System (ADS)

    Lüdde, Hans Jürgen; Horbatsch, Marko; Kirchner, Tom

    2018-05-01

    We apply a recently introduced model for an independent-atom-like calculation of ion-impact electron transfer and ionization cross sections to proton collisions from water, neon, and carbon clusters. The model is based on a geometrical interpretation of the cluster cross section as an effective area composed of overlapping circular disks that are representative of the atomic contributions. The latter are calculated using a time-dependent density-functional-theory-based single-particle description with accurate exchange-only ground-state potentials. We find that the net capture and ionization cross sections in p-X n collisions are proportional to n α with 2/3 ≤ α ≤ 1. For capture from water clusters at 100 keV impact energy α is close to one, which is substantially different from the value α = 2/3 predicted by a previous theoretical work based on the simplest-level electron nuclear dynamics method. For ionization at 100 keV and for capture at lower energies we find smaller α values than for capture at 100 keV. This can be understood by considering the magnitude of the atomic cross sections and the resulting overlaps of the circular disks that make up the cluster cross section in our model. Results for neon and carbon clusters confirm these trends. Simple parametrizations are found which fit the cross sections remarkably well and suggest that they depend on the relevant bond lengths.

  19. An Fe-S cluster in the conserved Cys-rich region in the catalytic subunit of FAD-dependent dehydrogenase complexes.

    PubMed

    Shiota, Masaki; Yamazaki, Tomohiko; Yoshimatsu, Keiichi; Kojima, Katsuhiro; Tsugawa, Wakako; Ferri, Stefano; Sode, Koji

    2016-12-01

    Several bacterial flavin adenine dinucleotide (FAD)-harboring dehydrogenase complexes comprise three distinct subunits: a catalytic subunit with FAD, a cytochrome c subunit containing three hemes, and a small subunit. Owing to the cytochrome c subunit, these dehydrogenase complexes have the potential to transfer electrons directly to an electrode. Despite various electrochemical applications and engineering studies of FAD-dependent dehydrogenase complexes, the intra/inter-molecular electron transfer pathway has not yet been revealed. In this study, we focused on the conserved Cys-rich region in the catalytic subunits using the catalytic subunit of FAD dependent glucose dehydrogenase complex (FADGDH) as a model, and site-directed mutagenesis and electron paramagnetic resonance (EPR) were performed. By co-expressing a hitch-hiker protein (γ-subunit) and a catalytic subunit (α-subunit), FADGDH γα complexes were prepared, and the properties of the catalytic subunit of both wild type and mutant FADGDHs were investigated. Substitution of the conserved Cys residues with Ser resulted in the loss of dye-mediated glucose dehydrogenase activity. ICP-AEM and EPR analyses of the wild-type FADGDH catalytic subunit revealed the presence of a 3Fe-4S-type iron-sulfur cluster, whereas none of the Ser-substituted mutants showed the EPR spectrum characteristic for this cluster. The results suggested that three Cys residues in the Cys-rich region constitute an iron-sulfur cluster that may play an important role in the electron transfer from FAD (intra-molecular) to the multi-heme cytochrome c subunit (inter-molecular) electron transfer pathway. These features appear to be conserved in the other three-subunit dehydrogenases having an FAD cofactor. Copyright © 2016 Elsevier B.V. All rights reserved.

  20. Identifying sighting clusters of endangered taxa with historical records.

    PubMed

    Duffy, Karl J

    2011-04-01

    The probability and time of extinction of taxa is often inferred from statistical analyses of historical records. Many of these analyses require the exclusion of multiple records within a unit of time (i.e., a month or a year). Nevertheless, spatially explicit, temporally aggregated data may be useful for identifying clusters of sightings (i.e., sighting clusters) in space and time. Identification of sighting clusters highlights changes in the historical recording of endangered taxa. I used two methods to identify sighting clusters in historical records: the Ederer-Myers-Mantel (EMM) test and the space-time permutation scan (STPS). I applied these methods to the spatially explicit sighting records of three species of orchids that are listed as endangered in the Republic of Ireland under the Wildlife Act (1976): Cephalanthera longifolia, Hammarbya paludosa, and Pseudorchis albida. Results with the EMM test were strongly affected by the choice of the time interval, and thus the number of temporal samples, used to examine the records. For example, sightings of P. albida clustered when the records were partitioned into 20-year temporal samples, but not when they were partitioned into 22-year temporal samples. Because the statistical power of EMM was low, it will not be useful when data are sparse. Nevertheless, the STPS identified regions that contained sighting clusters because it uses a flexible scanning window (defined by cylinders of varying size that move over the study area and evaluate the likelihood of clustering) to detect them, and it identified regions with high and regions with low rates of orchid sightings. The STPS analyses can be used to detect sighting clusters of endangered species that may be related to regions of extirpation and may assist in the categorization of threat status. ©2010 Society for Conservation Biology.

  1. Temperature Map of the Perseus Cluster of Galaxies Observed with ASCA

    NASA Technical Reports Server (NTRS)

    Furusho, T.; Yamasaki, N. Y.; Ohashi, T.; Shibata, R.; Ezawa, H.; White, Nicholas E. (Technical Monitor)

    2000-01-01

    We present two-dimensional temperature map of the Perseus cluster based on multi-pointing observations with the Advanced Spacecraft for Cosmology Astrophysics (ASCA) Gas Imaging Spectrometer (GIS), covering a region with a diameter of approximately 2 deg. By correcting for the effect of the X-ray telescope response, the temperatures were estimated from hardness ratios and the complete temperature structure of the cluster with a spatial resolution of about 100 kpc was obtained for the first time. There is an extended cool region with a diameter of approximately 20 arcmin and kT approx. 5 keV at about 20 arcmin east from the cluster center. This region also shows higher surface brightness and is surrounded by a large ring-like hot region with kT approx. > 7 keV, and likely to be a remnant of a merger with a poor cluster. Another extended cool region is extending outward from the IC 310 subcluster. These features and the presence of several other hot and cool blobs suggest that this rich cluster has been formed as a result of a repetition of many subcluster mergers.

  2. Relating Measurement Invariance, Cross-Level Invariance, and Multilevel Reliability.

    PubMed

    Jak, Suzanne; Jorgensen, Terrence D

    2017-01-01

    Data often have a nested, multilevel structure, for example when data are collected from children in classrooms. This kind of data complicate the evaluation of reliability and measurement invariance, because several properties can be evaluated at both the individual level and the cluster level, as well as across levels. For example, cross-level invariance implies equal factor loadings across levels, which is needed to give latent variables at the two levels a similar interpretation. Reliability at a specific level refers to the ratio of true score variance over total variance at that level. This paper aims to shine light on the relation between reliability, cross-level invariance, and strong factorial invariance across clusters in multilevel data. Specifically, we will illustrate how strong factorial invariance across clusters implies cross-level invariance and perfect reliability at the between level in multilevel factor models.

  3. Another shock for the Bullet cluster, and the source of seed electrons for radio relics

    NASA Astrophysics Data System (ADS)

    Shimwell, Timothy W.; Markevitch, Maxim; Brown, Shea; Feretti, Luigina; Gaensler, B. M.; Johnston-Hollitt, M.; Lage, Craig; Srinivasan, Raghav

    2015-05-01

    With Australia Telescope Compact Array observations, we detect a highly elongated Mpc-scale diffuse radio source on the eastern periphery of the Bullet cluster 1E 0657-55.8, which we argue has the positional, spectral and polarimetric characteristics of a radio relic. This powerful relic (2.3 ± 0.1 × 1025 W Hz-1) consists of a bright northern bulb and a faint linear tail. The bulb emits 94 per cent of the observed radio flux and has the highest surface brightness of any known relic. Exactly coincident with the linear tail, we find a sharp X-ray surface brightness edge in the deep Chandra image of the cluster - a signature of a shock front in the hot intracluster medium (ICM), located on the opposite side of the cluster to the famous bow shock. This new example of an X-ray shock coincident with a relic further supports the hypothesis that shocks in the outer regions of clusters can form relics via diffusive shock (re-)acceleration. Intriguingly, our new relic suggests that seed electrons for reacceleration are coming from a local remnant of a radio galaxy, which we are lucky to catch before its complete disruption. If this scenario, in which a relic forms when a shock crosses a well-defined region of the ICM polluted with aged relativistic plasma - as opposed to the usual assumption that seeds are uniformly mixed in the ICM - is also the case for other relics, this may explain a number of peculiar properties of peripheral relics.

  4. Another Shock for the Bullet Cluster, and the Source of Seed Electrons for Radio Relics

    NASA Technical Reports Server (NTRS)

    Shimwell, Timothy W,; Markevitch, Maxim; Brown, Shea; Feretti, Luigina; Gaensler, B. M.; Johnston-Hollitt, M.; Lage, Craig; Srinivasan, Raghav

    2015-01-01

    With Australia Telescope Compact Array observations, we detect a highly elongated Mpc-scale diffuse radio source on the eastern periphery of the Bullet cluster 1E 0657-55.8, which we argue has the positional, spectral and polarimetric characteristics of a radio relic. This powerful relic (2:30:11025 WHz(exp -1) consists of a bright northern bulb and a faint linear tail. The bulb emits 94% of the observed radio flux and has the highest surface brightness of any known relic. Exactly coincident with the linear tail we find a sharp X-ray surface brightness edge in the deep Chandra image of the cluster - a signature of a shock front in the hot intracluster medium (ICM), located on the opposite side of the cluster to the famous bow shock. This new example of an X-ray shock coincident with a relic further supports the hypothesis that shocks in the outer regions of clusters can form relics via diffusive shock (re- )acceleration. Intriguingly, our new relic suggests that seed electrons for reacceleration are coming from a local remnant of a radio galaxy, which we are lucky to catch before its complete disruption. If this scenario, in which a relic forms when a shock crosses a well-defined region of the ICM polluted with aged relativistic plasma - as opposed to the usual assumption that seeds are uniformly mixed in the ICM - is also the case for other relics, this may explain a number of peculiar properties of peripheral relics.

  5. The optical properties of galaxies in the Ophiuchus cluster

    NASA Astrophysics Data System (ADS)

    Durret, F.; Wakamatsu, K.; Adami, C.; Nagayama, T.; Omega Muleka Mwewa Mwaba, J. M.

    2018-05-01

    Context. Ophiuchus is one of the most massive clusters known, but due to its low Galactic latitude its optical properties remain poorly known. Aims: We investigate the optical properties of Ophiuchus to obtain clues on the formation epoch of this cluster, and compare them to those of the Coma cluster, which is comparable in mass to Ophiuchus but much more dynamically disturbed. Methods: Based on a deep image of the Ophiuchus cluster in the r' band obtained at the Canada France Hawaii Telescope with the MegaCam camera, we have applied an iterative process to subtract the contribution of the numerous stars that, due to the low Galactic latitude of the cluster, pollute the image, and have obtained a photometric catalogue of 2818 galaxies fully complete at r' = 20.5 mag and still 91% complete at r' = 21.5 mag. We use this catalogue to derive the cluster Galaxy Luminosity Function (GLF) for the overall image and for a region (hereafter the "rectangle" region) covering exactly the same physical size as the region in which the GLF of the Coma cluster was previously studied. We then compute density maps based on an adaptive kernel technique, for different magnitude limits, and define three circular regions covering 0.08, 0.08, and 0.06 deg2, respectively, centred on the cluster (C), on northwest (NW) of the cluster, and southeast (SE) of the cluster, in which we compute the GLFs. Results: The GLF fits are much better when a Gaussian is added to the usual Schechter function, to account for the excess of very bright galaxies. Compared to Coma, Ophiuchus shows a strong excess of bright galaxies. Conclusions: The properties of the two nearby very massive clusters Ophiuchus and Coma are quite comparable, though they seem embedded in different large-scale environments. Our interpretation is that Ophiuchus was built up long ago, as confirmed by its relaxed state (see paper I) while Coma is still in the process of forming. The photometric catalogue of Ophiuchus (full Table B.1) is

  6. The heavy ion diffusion region in magnetic reconnection in the Earth's magnetotail

    NASA Astrophysics Data System (ADS)

    Liu, Y. H.; Mouikis, C. G.; Kistler, L. M.; Wang, S.; Roytershteyn, V.; Karimabadi, H.

    2015-05-01

    While the plasma in the Earth's magnetotail predominantly consists of protons and electrons, there are times when a significant amount of oxygen is present. When magnetic reconnection occurs, the behavior of these heavy ions can be significantly different from that of the protons, due to their larger gyroradius. In this study, we investigate the heavy ion distribution functions in the reconnection ion diffusion region from a 2.5D three-species particle-in-cell numerical simulation and compare those with Cluster observations from the near-Earth magnetotail. From the simulation results, we find that the heavy ions are demagnetized and accelerated in a larger diffusion region, the heavy ion diffusion region. The ion velocity distribution functions show that, inside the heavy ion diffusion region, heavy ions appear as counterstreaming beams along z in the GSM x-z plane, while drifting in y, carrying cross-tail current. We compare this result with Cluster observations in the vicinity of reconnection regions in the near-Earth magnetotail and find that the simulation predictions are consistent with the observed ion distribution functions in the ion diffusion region, as well as the inflow, exhaust, and separatrix regions. Based on the simulation and observation results, the presence of a multiscale diffusion region model, for O+ abundant reconnection events in the Earth's magnetotail, is demonstrated. A test particle simulation shows that in the diffusion region, the H+ gains energy mainly through Ex, while the O+ energy gain comes equally from Ex and Ey.

  7. Chaos theory perspective for industry clusters development

    NASA Astrophysics Data System (ADS)

    Yu, Haiying; Jiang, Minghui; Li, Chengzhang

    2016-03-01

    Industry clusters have outperformed in economic development in most developing countries. The contributions of industrial clusters have been recognized as promotion of regional business and the alleviation of economic and social costs. It is no doubt globalization is rendering clusters in accelerating the competitiveness of economic activities. In accordance, many ideas and concepts involve in illustrating evolution tendency, stimulating the clusters development, meanwhile, avoiding industrial clusters recession. The term chaos theory is introduced to explain inherent relationship of features within industry clusters. A preferred life cycle approach is proposed for industrial cluster recessive theory analysis. Lyapunov exponents and Wolf model are presented for chaotic identification and examination. A case study of Tianjin, China has verified the model effectiveness. The investigations indicate that the approaches outperform in explaining chaos properties in industrial clusters, which demonstrates industrial clusters evolution, solves empirical issues and generates corresponding strategies.

  8. Wide-Field CCD Photometry around Nine Open Clusters

    NASA Astrophysics Data System (ADS)

    Sharma, Saurabh; Pandey, A. K.; Ogura, K.; Mito, H.; Tarusawa, K.; Sagar, R.

    2006-10-01

    In this paper we study the evolution of the core and corona of nine open clusters using the projected radial density profiles derived from homogeneous CCD photometric data obtained with the 105 cm Kiso Schmidt telescope. The age and galactocentric distance of the target clusters vary from 16 to 2000 Myr and 9 to 10.8 kpc, respectively. Barring Be 62, which is a young open cluster, other clusters show a uniform reddening across the cluster region. The reddening in Be 62 varies from E(B-V)min=0.70 mag to E(B-V)max=1.00 mag. The coronae of six of the clusters in the present sample are found to be elongated; however, on the basis of the present sample it is not possible to establish any correlation between the age and shape of the core. The elongated core in the case of the young cluster Be 62 may reflect the initial conditions in the parental molecular cloud. The other results of the present study are as follows: (1) Core radius rc and corona size rcn/cluster radius rcl are linearly correlated. (2) The rc, rcn, and rcl are linearly correlated with the number of stars in that region. (3) In the age range 10-1000 Myr, the core and corona shrink with age. (4) We find that in the galactocentric distance range 9-10 kpc, the core and corona/cluster extent of the clusters increase with the galactocentric distance.

  9. The young star cluster population of M51 with LEGUS - II. Testing environmental dependences

    NASA Astrophysics Data System (ADS)

    Messa, Matteo; Adamo, A.; Calzetti, D.; Reina-Campos, M.; Colombo, D.; Schinnerer, E.; Chandar, R.; Dale, D. A.; Gouliermis, D. A.; Grasha, K.; Grebel, E. K.; Elmegreen, B. G.; Fumagalli, M.; Johnson, K. E.; Kruijssen, J. M. D.; Östlin, G.; Shabani, F.; Smith, L. J.; Whitmore, B. C.

    2018-06-01

    It has recently been established that the properties of young star clusters (YSCs) can vary as a function of the galactic environment in which they are found. We use the cluster catalogue produced by the Legacy Extragalactic UV Survey (LEGUS) collaboration to investigate cluster properties in the spiral galaxy M51. We analyse the cluster population as a function of galactocentric distance and in arm and inter-arm regions. The cluster mass function exhibits a similar shape at all radial bins, described by a power law with a slope close to -2 and an exponential truncation around 105 M⊙. While the mass functions of the YSCs in the spiral arm and inter-arm regions have similar truncation masses, the inter-arm region mass function has a significantly steeper slope than the one in the arm region, a trend that is also observed in the giant molecular cloud mass function and predicted by simulations. The age distribution of clusters is dependent on the region considered, and is consistent with rapid disruption only in dense regions, while little disruption is observed at large galactocentric distances and in the inter-arm region. The fraction of stars forming in clusters does not show radial variations, despite the drop in the H2 surface density measured as a function of galactocentric distance. We suggest that the higher disruption rate observed in the inner part of the galaxy is likely at the origin of the observed flat cluster formation efficiency radial profile.

  10. Cross-cultural consistency and diversity in intrinsic functional organization of Broca's Region.

    PubMed

    Zhang, Yu; Fan, Lingzhong; Caspers, Svenja; Heim, Stefan; Song, Ming; Liu, Cirong; Mo, Yin; Eickhoff, Simon B; Amunts, Katrin; Jiang, Tianzi

    2017-04-15

    As a core language area, Broca's region was consistently activated in a variety of language studies even across different language systems. Moreover, a high degree of structural and functional heterogeneity in Broca's region has been reported in many studies. This raised the issue of how the intrinsic organization of Broca's region effects by different language experiences in light of its subdivisions. To address this question, we used multi-center resting-state fMRI data to explore the cross-cultural consistency and diversity of Broca's region in terms of its subdivisions, connectivity patterns and modularity organization in Chinese and German speakers. A consistent topological organization of the 13 subdivisions within the extended Broca's region was revealed on the basis of a new in-vivo parcellation map, which corresponded well to the previously reported receptorarchitectonic map. Based on this parcellation map, consistent functional connectivity patterns and modularity organization of these subdivisions were found. Some cultural difference in the functional connectivity patterns was also found, for instance stronger connectivity in Chinese subjects between area 6v2 and the motor hand area, as well as higher correlations between area 45p and middle frontal gyrus. Our study suggests that a generally invariant organization of Broca's region, together with certain regulations of different language experiences on functional connectivity, might exists to support language processing in human brain. Copyright © 2017 Elsevier Inc. All rights reserved.

  11. Genus Calliophis of Asiatic coral snakes: A deficiency of venom cross-reactivity and neutralization against seven regional elapid antivenoms.

    PubMed

    Tan, Choo Hock; Liew, Jia Lee; Tan, Kae Yi; Tan, Nget Hong

    2016-10-01

    Venoms of Calliophis bivirgata and Calliophis intestinalis exhibited moderate binding activities toward Neuro Bivalent Antivenom (Taiwan) but not the other six elapid monovalent or bivalent antivenoms available in the region. All antivenoms failed to neutralize C. bivirgata venom lethality in mice. The findings indicate the need to validate antivenom cross-reactivity with in vivo cross-neutralization, and imply that distinct antigens of Calliophis venoms should be incorporated in the production of a pan-regional poly-specific antivenom. Copyright © 2016 Elsevier Ltd. All rights reserved.

  12. Color gradients in cooling flow cluster central galaxies and the ionization of cluster emission line systems

    NASA Technical Reports Server (NTRS)

    Romanishin, W.

    1988-01-01

    Preliminary results are given for a program to measure color gradients in the central galaxies in clusters with a variety of cooling flow rates. The objectives are to search for extended blue continuum regions indicative of star formation, to study the spatial distribution of star formation, and to make a quantitative measure of the amount of light from young stars, which can lead to a measure of the star formation rate (for an assumed initial mass function). Four clusters with large masses and large cluster H-alpha emission fluxes are found to have an excess of blue light concentrated to the centers of the cluster central galaxy. Assumption of a disk IMF leads to the conclusion that the starlight might play a major role in ionizing the emission line gas in these clusters.

  13. A populous intermediate-age open cluster and evidence of an embedded cluster among the FSR globular cluster candidates

    NASA Astrophysics Data System (ADS)

    Bica, E.; Bonatto, C.

    2008-03-01

    We study the nature of the globular cluster (GC) candidates FSR 1603 and FSR1755 selected from the catalogue of Froebrich, Scholz & Raftery. Their properties are investigated with Two-Micron All-Sky Survey field-star decontaminated photometry, which is used to build colour-magnitude diagrams (CMDs) and stellar radial density profiles. FSR1603 has the open cluster Ruprecht 101 as optical counterpart, and we show it to be a massive intermediate-age cluster. Relevant parameters of FSR1603 are the age ~1Gyr, distance from the Sun dsolar ~ 2.7kpc, Galactocentric distance RGC ~ 6.4kpc, core radius RC ~ 1.1pc, mass function slope χ ~ 1.8, observed stellar mass (for stars with mass in the range 1.27 <= m <= 2.03Msolar) Mobs ~ 500Msolar and a total (extrapolated to m = 0.08Msolar) stellar mass Mtot ~ 2300Msolar. FSR1755, on the other hand, is not a populous cluster. It may be a sparse young cluster embedded in the HII region Sh2-3, subject to an absorption AV ~ 4.1, located at dsolar ~ 1.3kpc. Important field-star contamination, spatially variable heavy dust obscuration, even in Ks, and gas emission characterize its field. A nearly vertical, sparse blue stellar sequence shows up in the CMDs.

  14. Combining cluster number counts and galaxy clustering

    NASA Astrophysics Data System (ADS)

    Lacasa, Fabien; Rosenfeld, Rogerio

    2016-08-01

    The abundance of clusters and the clustering of galaxies are two of the important cosmological probes for current and future large scale surveys of galaxies, such as the Dark Energy Survey. In order to combine them one has to account for the fact that they are not independent quantities, since they probe the same density field. It is important to develop a good understanding of their correlation in order to extract parameter constraints. We present a detailed modelling of the joint covariance matrix between cluster number counts and the galaxy angular power spectrum. We employ the framework of the halo model complemented by a Halo Occupation Distribution model (HOD). We demonstrate the importance of accounting for non-Gaussianity to produce accurate covariance predictions. Indeed, we show that the non-Gaussian covariance becomes dominant at small scales, low redshifts or high cluster masses. We discuss in particular the case of the super-sample covariance (SSC), including the effects of galaxy shot-noise, halo second order bias and non-local bias. We demonstrate that the SSC obeys mathematical inequalities and positivity. Using the joint covariance matrix and a Fisher matrix methodology, we examine the prospects of combining these two probes to constrain cosmological and HOD parameters. We find that the combination indeed results in noticeably better constraints, with improvements of order 20% on cosmological parameters compared to the best single probe, and even greater improvement on HOD parameters, with reduction of error bars by a factor 1.4-4.8. This happens in particular because the cross-covariance introduces a synergy between the probes on small scales. We conclude that accounting for non-Gaussian effects is required for the joint analysis of these observables in galaxy surveys.

  15. Application of trajectory clustering and source attribution methods for investigating regional CO2 and CH4 concentrations at Germany's highest mountain site

    NASA Astrophysics Data System (ADS)

    Giemsa, Esther; Jacobeit, Jucundus; Ries, Ludwig; Frank, Gabriele; Hachinger, Stephan; Meyer-Arnek, Julian

    2017-04-01

    Carbon dioxide (CO2) and methane (CH4) represent the most important contributors to increased radiative forcing enhancing it together by contemporary 2.65 W/m2 on the global average (IPCC 2013). The unbroken increase of atmospheric greenhouse gases (GHG) has been unequivocally attributed to human emissions mainly coming from fossil fuel burning and land-use changes, while the oceans and terrestrial ecosystems slightly attenuate this rise with seasonally varying strength. Short-term fluctuations in the GHG concentrations that superimpose the seasonal cycle and the climate change driven trend reflect the presence of regional sources and sinks. A perfect place for investigating the comprehensive influence of these regional emissions is provided by the Environmental Research Station Schneefernerhaus (47.42°N, 10.98°E, 2.650m a.s.l.) situated in the eastern Alps at the southern side of Zugspitze mountain. Located just 300m below the highest peak of the German Alps, the exposed site is one of the currently 30 global core sites of the World Meteorological Organisation (WMO) Global Atmosphere Watch (GAW) programme and thus provides ideal conditions to study source-receptor relationships for greenhouse gases. We propose a stepwise statistical methodology for examining the relationship between synoptic-scale atmospheric transport patterns and climate gas mole fractions to finally receive a characterization of the sampling site with regard to the key processes driving CO2 and CH4 concentration levels. The first step entails a reliable radon-based filtering approach to subdivide the detected air masses according to their regional or 'background' origin. Simultaneously, a large number of ten-day back-trajectories from Schneefernerhaus every two hours over the entire study period 2011 - 2015 is calculated with the Lagrangian transport and dispersion model FLEXPART (Stohl et al. 2005) and subjected to cluster analysis. The weather- and emission strength-related (short

  16. A model for the infrared emission from an OB star cluster environment

    NASA Technical Reports Server (NTRS)

    Leisawitz, D.

    1991-01-01

    A model for the infrared emission from the neighborhood of an OB star cluster is described. The distribution of gas and dust around the stars, properties of the dust, and the cluster and interstellar radiation fields are variable. The model can be applied to regions around clusters embedded to various degrees in their parental molecular clouds (i.e., compact H II regions, blister-type H II regions, and the tenuous H II regions ionized by naked O stars). The model is used to simulate IRAS observations of a typical blister H II region. Infrared surface brightness and spectral energy distributions are predicted and the impact of limited spatial resolution is illustrated. The model results are shown to be consistent with observations of the exemplary outer Galaxy OB cluster NGC 7380. It is planned to use the model as a diagnostic tool to probe the physical conditions and dust properties in star-formation regions and, ultimately, in an interpretation of the spectral energy distributions of spiral galaxies.

  17. Robust root clustering for linear uncertain systems using generalized Lyapunov theory

    NASA Technical Reports Server (NTRS)

    Yedavalli, R. K.

    1993-01-01

    Consideration is given to the problem of matrix root clustering in subregions of a complex plane for linear state space models with real parameter uncertainty. The nominal matrix root clustering theory of Gutman & Jury (1981) using the generalized Liapunov equation is extended to the perturbed matrix case, and bounds are derived on the perturbation to maintain root clustering inside a given region. The theory makes it possible to obtain an explicit relationship between the parameters of the root clustering region and the uncertainty range of the parameter space.

  18. Multi-level multi-task learning for modeling cross-scale interactions in nested geospatial data

    USGS Publications Warehouse

    Yuan, Shuai; Zhou, Jiayu; Tan, Pang-Ning; Fergus, Emi; Wagner, Tyler; Sorrano, Patricia

    2017-01-01

    Predictive modeling of nested geospatial data is a challenging problem as the models must take into account potential interactions among variables defined at different spatial scales. These cross-scale interactions, as they are commonly known, are particularly important to understand relationships among ecological properties at macroscales. In this paper, we present a novel, multi-level multi-task learning framework for modeling nested geospatial data in the lake ecology domain. Specifically, we consider region-specific models to predict lake water quality from multi-scaled factors. Our framework enables distinct models to be developed for each region using both its local and regional information. The framework also allows information to be shared among the region-specific models through their common set of latent factors. Such information sharing helps to create more robust models especially for regions with limited or no training data. In addition, the framework can automatically determine cross-scale interactions between the regional variables and the local variables that are nested within them. Our experimental results show that the proposed framework outperforms all the baseline methods in at least 64% of the regions for 3 out of 4 lake water quality datasets evaluated in this study. Furthermore, the latent factors can be clustered to obtain a new set of regions that is more aligned with the response variables than the original regions that were defined a priori from the ecology domain.

  19. Star-Forming Galaxies in the Hercules Cluster: Hα Imaging of A2151

    NASA Astrophysics Data System (ADS)

    Cedrés, Bernabé; Iglesias-Páramo, Jorge; Vílchez, José Manuel; Reverte, Daniel; Petropoulou, Vasiliki; Hernández-Fernández, Jonathan

    2009-09-01

    This paper presents the first results of an Hα imaging survey of galaxies in the central regions of the A2151 cluster. A total of 50 sources were detected in Hα, from which 41 were classified as secure members of the cluster and 2 as likely members based on spectroscopic and photometric redshift considerations. The remaining seven galaxies were classified as background contaminants and thus excluded from our study on the Hα properties of the cluster. The morphologies of the 43 Hα selected galaxies range from grand design spirals and interacting galaxies to blue compacts and tidal dwarfs or isolated extragalactic H II regions, spanning a range of magnitudes of -21 <= MB <= -12.5 mag. From these 43 galaxies, 7 have been classified as active galactic nucleus (AGN) candidates. These AGN candidates follow the L(Hα) versus MB relationship of the normal galaxies, implying that the emission associated with the nuclear engine has a rather secondary impact on the total Hα emission of these galaxies. A comparison with the clusters Coma and A1367 and a sample of field galaxies has shown the presence of cluster galaxies with L(Hα) lower than expected for their MB , a consequence of the cluster environment. This fact results in differences in the L(Hα) versus EW(Hα) and L(Hα) distributions of the clusters with respect to the field, and in cluster-to-cluster variations of these quantities, which we propose are driven by a global cluster property as the total mass. In addition, the cluster Hα emitting galaxies tend to avoid the central regions of the clusters, again with different intensity depending on the cluster total mass. For the particular case of A2151, we find that most Hα emitting galaxies are located close to the regions with the higher galaxy density, offset from the main X-ray peak. Overall, we conclude that both the global cluster environment and the cluster merging history play a non-negligible role in the integral star formation properties of clusters of

  20. The Cluster Environment of Two High-mass Protostars

    NASA Astrophysics Data System (ADS)

    Montes, Virginie; Hofner, Peter

    2017-06-01

    Characterizing the environment and stellar population in which high-mass stars form is an important step to decide between the main massive star formation theories. In the monolithic collapse model, the mass of the core will determine the final stellar mass (e.g., McKee & Tan 2003). In contrast, in the competitive accretion model (e.g., Bonnell & Bate 2006), the mass of the high-mass star is related to the properties of the cluster. As dynamical processes substantially affect the appearance of a cluster, we study early stages of high-mass star formation. These regions often show extended emission from hot dust at infrared wavelengths, which can cause difficulties to define the cluster. We use a multi-wavelength technique to study nearby high-mass star clusters, based on X-ray observations with the Chandra X-Ray Telescope, in conjunction with infrared data and VLA data. The technique relies on the fact that YSOs are particularly bright in X-ray and that contamination is relatively small. X-ray observations allow us to determine the cluster size. The cluster membership and YSOs classification is established using infrared identification of the X-ray sources, and color-color and color-magnitude diagrams.In this talk, I will present our findings on the cluster study of two high-mass star forming regions: IRAS 20126+4104 and IRAS 16562-3959. While most massive stars appear to be formed in rich a cluster environment, those two sources are candidates for the formation of massive stars in a relatively poor cluster. In contrast to what was found in previous studies (Qiu et al. 2008), the dominant B0-type protostar in IRAS 20126+4104 is associated with a small cluster of low-mass stars. I will also show our current work on IRAS 16562-3959, which contains one of the most luminous O-type protostars in the Galaxy. In the vicinity of this particularly interesting region there is a multitude of small clusters, for which I will present how their stellar population differ from the

  1. Discriminating Mining Induced Seismicity from Natural Tectonic Earthquakes in the Wasatch Plateau Region of Central Utah

    NASA Astrophysics Data System (ADS)

    Stein, J. R.; Pankow, K. L.; Koper, K. D.; McCarter, M. K.

    2014-12-01

    On average, several hundred earthquakes are located each year within the Wasatch Plateau region of central Utah. This region includes the boundary between the relatively stable Colorado Plateau and the actively extending Basin and Range physiographic provinces. Earthquakes in this region tend to fall in the intermountain seismic belt (ISB), a continuous band of seismicity that extends from Montana to Arizona. While most of the earthquakes in the ISB are of tectonic origin, events in the Wasatch Plateau also include mining induced seismicity (MIS) from local underground coal mining operations. Using a catalog of 16,182 seismic events (-0.25 < M < 4.5) recorded from 1981 to 2011, we use double difference relocation and waveform cross correlation techniques to help discriminate between these two populations of events. Double difference relocation greatly improves the relative locations between the many events that occur in this area. From the relative relocations, spatial differences between event types are used to differentiate between shallow MIS and considerably deeper events associated with tectonic seismicity. Additionally, waveform cross-correlation is used to cluster events with similar waveforms—meaning that events in each cluster should have a similar source location and mechanism—in order to more finely group seismic events occurring in the Wasatch Plateau. The results of this study provide both an increased understanding of the influence mining induced seismicity has on the number of earthquakes detected within this region, as well as better constraints on the deeper tectonic structure.

  2. Connectivity-based fixel enhancement: Whole-brain statistical analysis of diffusion MRI measures in the presence of crossing fibres

    PubMed Central

    Raffelt, David A.; Smith, Robert E.; Ridgway, Gerard R.; Tournier, J-Donald; Vaughan, David N.; Rose, Stephen; Henderson, Robert; Connelly, Alan

    2015-01-01

    In brain regions containing crossing fibre bundles, voxel-average diffusion MRI measures such as fractional anisotropy (FA) are difficult to interpret, and lack within-voxel single fibre population specificity. Recent work has focused on the development of more interpretable quantitative measures that can be associated with a specific fibre population within a voxel containing crossing fibres (herein we use fixel to refer to a specific fibre population within a single voxel). Unfortunately, traditional 3D methods for smoothing and cluster-based statistical inference cannot be used for voxel-based analysis of these measures, since the local neighbourhood for smoothing and cluster formation can be ambiguous when adjacent voxels may have different numbers of fixels, or ill-defined when they belong to different tracts. Here we introduce a novel statistical method to perform whole-brain fixel-based analysis called connectivity-based fixel enhancement (CFE). CFE uses probabilistic tractography to identify structurally connected fixels that are likely to share underlying anatomy and pathology. Probabilistic connectivity information is then used for tract-specific smoothing (prior to the statistical analysis) and enhancement of the statistical map (using a threshold-free cluster enhancement-like approach). To investigate the characteristics of the CFE method, we assessed sensitivity and specificity using a large number of combinations of CFE enhancement parameters and smoothing extents, using simulated pathology generated with a range of test-statistic signal-to-noise ratios in five different white matter regions (chosen to cover a broad range of fibre bundle features). The results suggest that CFE input parameters are relatively insensitive to the characteristics of the simulated pathology. We therefore recommend a single set of CFE parameters that should give near optimal results in future studies where the group effect is unknown. We then demonstrate the proposed method

  3. Gas stripping in galaxy clusters: a new SPH simulation approach

    NASA Astrophysics Data System (ADS)

    Jáchym, P.; Palouš, J.; Köppen, J.; Combes, F.

    2007-09-01

    Aims:The influence of a time-varying ram pressure on spiral galaxies in clusters is explored with a new simulation method based on the N-body SPH/tree code GADGET. Methods: We have adapted the code to describe the interaction of two different gas phases, the diffuse hot intracluster medium (ICM) and the denser and colder interstellar medium (ISM). Both the ICM and ISM components are introduced as SPH particles. As a galaxy arrives on a highly radial orbit from outskirts to cluster center, it crosses the ICM density peak and experiences a time-varying wind. Results: Depending on the duration and intensity of the ISM-ICM interaction, early and late type galaxies in galaxy clusters with either a large or small ICM distribution are found to show different stripping efficiencies, amounts of reaccretion of the extra-planar ISM, and final masses. We compare the numerical results with analytical approximations of different complexity and indicate the limits of the Gunn & Gott simple stripping formula. Conclusions: Our investigations emphasize the role of the galactic orbital history to the stripping amount. We discuss the contribution of ram pressure stripping to the origin of the ICM and its metallicity. We propose gas accumulations like tails, filaments, or ripples to be responsible for stripping in regions with low overall ICM occurrence. Appendix A is only available in electronic form at http://www.aanda.org

  4. Clusters of community exposure to coastal flooding hazards based on storm and sea level rise scenarios—implications for adaptation networks in the San Francisco Bay region

    USGS Publications Warehouse

    Hummel, Michelle; Wood, Nathan J.; Schweikert, Amy; Stacey, Mark T.; Jones, Jeanne; Barnard, Patrick L.; Erikson, Li H.

    2018-01-01

    Sea level is projected to rise over the coming decades, further increasing the extent of flooding hazards in coastal communities. Efforts to address potential impacts from climate-driven coastal hazards have called for collaboration among communities to strengthen the application of best practices. However, communities currently lack practical tools for identifying potential partner communities based on similar hazard exposure characteristics. This study uses statistical cluster analysis to identify similarities in community exposure to flooding hazards for a suite of sea level rise and storm scenarios. We demonstrate this approach using 63 jurisdictions in the San Francisco Bay region of California (USA) and compare 21 distinct exposure variables related to residents, employees, and structures for six hazard scenario combinations of sea level rise and storms. Results indicate that cluster analysis can provide an effective mechanism for identifying community groupings. Cluster compositions changed based on the selected societal variables and sea level rise scenarios, suggesting that a community could participate in multiple networks to target specific issues or policy interventions. The proposed clustering approach can serve as a data-driven foundation to help communities identify other communities with similar adaptation challenges and to enhance regional efforts that aim to facilitate adaptation planning and investment prioritization.

  5. Self-organizing map network-based precipitation regionalization for the Tibetan Plateau and regional precipitation variability

    NASA Astrophysics Data System (ADS)

    Wang, Nini; Yin, Jianchuan

    2017-12-01

    A precipitation-based regionalization for the Tibetan Plateau (TP) was investigated for regional precipitation trend analysis and frequency analysis using data from 1113 grid points covering the period 1900-2014. The results utilizing self-organizing map (SOM) network suggest that four clusters of precipitation coherent zones can be identified, including the southwestern edge, the southern edge, the southeastern region, and the north central region. Regionalization results of the SOM network satisfactorily represent the influences of the atmospheric circulation systems such as the East Asian summer monsoon, the south Asian summer monsoon, and the mid-latitude westerlies. Regionalization results also well display the direct impacts of physical geographical features of the TP such as orography, topography, and land-sea distribution. Regional-scale annual precipitation trend as well as regional differences of annual and seasonal total precipitation were investigated by precipitation index such as precipitation concentration index (PCI) and Standardized Anomaly Index (SAI). Results demonstrate significant negative long-term linear trends in southeastern TP and the north central part of the TP, indicating arid and semi-arid regions in the TP are getting drier. The empirical mode decomposition (EMD) method shows an evolution of the main cycle with 4 and 12 months for all the representative grids of four sub-regions. The cross-wavelet analysis suggests that predominant and effective period of Indian Ocean Dipole (IOD) on monthly precipitation is around ˜12 months, except for the representative grid of the northwestern region.

  6. Effects of Cluster Environment on Chemical Abundances in Virgo Cluster Spirals

    NASA Astrophysics Data System (ADS)

    Kennicutt, R. C.; Skillman, E. D.; Shields, G. A.; Zaritsky, D.

    1995-12-01

    We have obtained new chemical abundance measurements of HII regions in Virgo cluster spiral galaxies, in order to test whether the cluster environment has significantly influenced the gas-phase abundances and chemical evolution of spiral disks. The sample of 9 Virgo spirals covers a narrow range of morphological type (Sbc - Sc) but shows broad ranges in HI deficiencies and radii in the cluster. This allows us to compare the Virgo sample as a whole to field spirals, using a large sample from Zaritsky, Kennicutt, & Huchra, and to test for systematic trends with HI content and location within the cluster. The Virgo spirals show a wide dispersion in mean disk abundances and abundance gradients. Strongly HI deficient spirals closest to the cluster core show anomalously high oxygen abundances (by 0.3 to 0.5 dex), while outlying spirals with normal HI content show abundances similar to those of field spirals. The most HI depleted spirals also show weaker abundance gradients on average, but the formal significance of this trend is marginal. We find a strong correlation between mean abundance and HI/optical diameter ratio that is quite distinct from the behavior seen in field galaxies. This suggests that dynamical processes associated with the cluster environment are more important than cluster membership in determining the evolution of chemical abundances and stellar populations in spiral galaxies. Simple chemical evolution models are calculated to predict the magnitude of the abundance enhancement expected if ram-pressure stripping or curtailment of infall is responsible for the gas deficiencies. The increased abundances of the spirals in the cluster core may have significant effects on their use as cosmological standard candles.

  7. Hydrodynamic clustering of droplets in turbulence

    NASA Astrophysics Data System (ADS)

    Kunnen, Rudie; Yavuz, Altug; van Heijst, Gertjan; Clercx, Herman

    2017-11-01

    Small, inertial particles are known to cluster in turbulent flows: particles are centrifuged out of eddies and gather in the strain-dominated regions. This so-called preferential concentration is reflected in the radial distribution function (RDF; a quantitative measure of clustering). We study clustering of water droplets in a loudspeaker-driven turbulence chamber. We track the motion of droplets in 3D and calculate the RDF. At moderate scales (a few Kolmogorov lengths) we find the typical power-law scaling of preferential concentration in the RDF. However, at even smaller scales (a few droplet diameters), we encounter a hitherto unobserved additional clustering. We postulate that the additional clustering is due to hydrodynamic interactions, an effect which is typically disregarded in modeling. Using a perturbative expansion of inertial effects in a Stokes-flow description of two interacting spheres, we obtain an expression for the RDF which indeed includes the additional clustering. The additional clustering enhances the collision probability of droplets, which enhances their growth rate due to coalescence. The additional clustering is thus an essential effect in precipitation modeling.

  8. Customized recommendations for production management clusters of North American automatic milking systems.

    PubMed

    Tremblay, Marlène; Hess, Justin P; Christenson, Brock M; McIntyre, Kolby K; Smink, Ben; van der Kamp, Arjen J; de Jong, Lisanne G; Döpfer, Dörte

    2016-07-01

    Automatic milking systems (AMS) are implemented in a variety of situations and environments. Consequently, there is a need to characterize individual farming practices and regional challenges to streamline management advice and objectives for producers. Benchmarking is often used in the dairy industry to compare farms by computing percentile ranks of the production values of groups of farms. Grouping for conventional benchmarking is commonly limited to the use of a few factors such as farms' geographic region or breed of cattle. We hypothesized that herds' production data and management information could be clustered in a meaningful way using cluster analysis and that this clustering approach would yield better peer groups of farms than benchmarking methods based on criteria such as country, region, breed, or breed and region. By applying mixed latent-class model-based cluster analysis to 529 North American AMS dairy farms with respect to 18 significant risk factors, 6 clusters were identified. Each cluster (i.e., peer group) represented unique management styles, challenges, and production patterns. When compared with peer groups based on criteria similar to the conventional benchmarking standards, the 6 clusters better predicted milk produced (kilograms) per robot per day. Each cluster represented a unique management and production pattern that requires specialized advice. For example, cluster 1 farms were those that recently installed AMS robots, whereas cluster 3 farms (the most northern farms) fed high amounts of concentrates through the robot to compensate for low-energy feed in the bunk. In addition to general recommendations for farms within a cluster, individual farms can generate their own specific goals by comparing themselves to farms within their cluster. This is very comparable to benchmarking but adds the specific characteristics of the peer group, resulting in better farm management advice. The improvement that cluster analysis allows for is

  9. Analysis of earthquake clustering and source spectra in the Salton Sea Geothermal Field

    NASA Astrophysics Data System (ADS)

    Cheng, Y.; Chen, X.

    2015-12-01

    The Salton Sea Geothermal field is located within the tectonic step-over between San Andreas Fault and Imperial Fault. Since the 1980s, geothermal energy exploration has resulted with step-like increase of microearthquake activities, which mirror the expansion of geothermal field. Distinguishing naturally occurred and induced seismicity, and their corresponding characteristics (e.g., energy release) is important for hazard assessment. Between 2008 and 2014, seismic data recorded by a local borehole array were provided public access from CalEnergy through SCEC data center; and the high quality local recording of over 7000 microearthquakes provides unique opportunity to sort out characteristics of induced versus natural activities. We obtain high-resolution earthquake location using improved S-wave picks, waveform cross-correlation and a new 3D velocity model. We then develop method to identify spatial-temporally isolated earthquake clusters. These clusters are classified into aftershock-type, swarm-type, and mixed-type (aftershock-like, with low skew, low magnitude and shorter duration), based on the relative timing of largest earthquakes and moment-release. The mixed-type clusters are mostly located at 3 - 4 km depth near injection well; while aftershock-type clusters and swarm-type clusters also occur further from injection well. By counting number of aftershocks within 1day following mainshock in each cluster, we find that the mixed-type clusters have much higher aftershock productivity compared with other types and historic M4 earthquakes. We analyze detailed spatial variation of 'b-value'. We find that the mixed-type clusters are mostly located within high b-value patches, while large (M>3) earthquakes and other types of clusters are located within low b-value patches. We are currently processing P and S-wave spectra to analyze the spatial-temporal correlation of earthquake stress parameter and seismicity characteristics. Preliminary results suggest that the

  10. Ab initio calculations of optical properties of silver clusters: cross-over from molecular to nanoscale behavior

    NASA Astrophysics Data System (ADS)

    Titantah, John T.; Karttunen, Mikko

    2016-05-01

    Electronic and optical properties of silver clusters were calculated using two different ab initio approaches: (1) based on all-electron full-potential linearized-augmented plane-wave method and (2) local basis function pseudopotential approach. Agreement is found between the two methods for small and intermediate sized clusters for which the former method is limited due to its all-electron formulation. The latter, due to non-periodic boundary conditions, is the more natural approach to simulate small clusters. The effect of cluster size is then explored using the local basis function approach. We find that as the cluster size increases, the electronic structure undergoes a transition from molecular behavior to nanoparticle behavior at a cluster size of 140 atoms (diameter ~1.7 nm). Above this cluster size the step-like electronic structure, evident as several features in the imaginary part of the polarizability of all clusters smaller than Ag147, gives way to a dominant plasmon peak localized at wavelengths 350 nm ≤ λ ≤ 600 nm. It is, thus, at this length-scale that the conduction electrons' collective oscillations that are responsible for plasmonic resonances begin to dominate the opto-electronic properties of silver nanoclusters.

  11. Intracluster age gradients in numerous young stellar clusters

    NASA Astrophysics Data System (ADS)

    Getman, K. V.; Feigelson, E. D.; Kuhn, M. A.; Bate, M. R.; Broos, P. S.; Garmire, G. P.

    2018-05-01

    The pace and pattern of star formation leading to rich young stellar clusters is quite uncertain. In this context, we analyse the spatial distribution of ages within 19 young (median t ≲ 3 Myr on the Siess et al. time-scale), morphologically simple, isolated, and relatively rich stellar clusters. Our analysis is based on young stellar object (YSO) samples from the Massive Young Star-Forming Complex Study in Infrared and X-ray and Star Formation in Nearby Clouds surveys, and a new estimator of pre-main sequence (PMS) stellar ages, AgeJX, derived from X-ray and near-infrared photometric data. Median cluster ages are computed within four annular subregions of the clusters. We confirm and extend the earlier result of Getman et al. (2014): 80 per cent of the clusters show age trends where stars in cluster cores are younger than in outer regions. Our cluster stacking analyses establish the existence of an age gradient to high statistical significance in several ways. Time-scales vary with the choice of PMS evolutionary model; the inferred median age gradient across the studied clusters ranges from 0.75 to 1.5 Myr pc-1. The empirical finding reported in the present study - late or continuing formation of stars in the cores of star clusters with older stars dispersed in the outer regions - has a strong foundation with other observational studies and with the astrophysical models like the global hierarchical collapse model of Vázquez-Semadeni et al.

  12. Central San Juan caldera cluster: Regional volcanic framework

    USGS Publications Warehouse

    Lipman, Peter W.

    2000-01-01

    Eruption of at least 8800 km3 of dacitic-rhyolitic magma as 9 major ash-slow sheets (individually 150-5000 km3) was accompanied by recurrent caldera subsidence between 28.3 and about 26.5 Ma in the central San Juan Mountains, Colorado. Voluminous andesitic-decitic lavas and breccias were erupted from central volcanoes prior to the ash-flow eruptions, and similar lava eruptions continued within and adjacent to the calderas during the period of explosive volcanism, making the central San Juan caldera cluster an exceptional site for study of caldera-related volcanic processes. Exposed calderas vary in size from 10 to 75 km in maximum diameter, the largest calderas being associated with the most voluminous eruptions. After collapse of the giant La Garita caldera during eruption if the Fish Canyon Tuff at 17.6 Ma, seven additional explosive eruptions and calderas formed inside the La Garita depression within about 1 m.y. Because of the nested geometry, maximum loci of recurrently overlapping collapse events are inferred to have subsided as much as 10-17 km, far deeper than the roof of the composite subvolcanic batholith defined by gravity data, which represents solidified caldera-related magma bodies. Erosional dissection to depths of as much as 1.5 km, although insufficient to reach the subvolcanic batholith, has exposed diverse features of intracaldera ash-flow tuff and interleaved caldera-collapse landslide deposits that accumulated to multikilometer thickness within concurrently subsiding caldera structures. The calderas display a variety of postcollapse resurgent uplift structures, and caldera-forming events produced complex fault geometries that localized late mineralization, including the epithermal base- and precious-metal veins of the well-known Creede mining district. Most of the central San Juan calderas have been deeply eroded, and their identification is dependent on detailed geologic mapping. In contrast, the primary volcanic morphology of the

  13. Fission of Polyanionic Metal Clusters

    NASA Astrophysics Data System (ADS)

    König, S.; Jankowski, A.; Marx, G.; Schweikhard, L.; Wolfram, M.

    2018-04-01

    Size-selected dianionic lead clusters Pbn2 -, n =34 - 56 , are stored in a Penning trap and studied with respect to their decay products upon photoexcitation. Contrary to the decay of other dianionic metal clusters, these lead clusters show a variety of decay channels. The mass spectra of the fragments are compared to the corresponding spectra of the monoanionic precursors. This comparison leads to the conclusion that, in the cluster size region below about n =48 , the fission reaction Pbn2 -→Pbn-10 -+Pb10- is the major decay process. Its disappearance at larger cluster sizes may be an indication of a nonmetal to metal transition. Recently, the pair of Pb10- and Pbn-10 - were observed as pronounced fragments in electron-attachment studies [S. König et al., Int. J. Mass Spectrom. 421, 129 (2017), 10.1016/j.ijms.2017.06.009]. The present findings suggest that this combination is the fingerprint of the decay of doubly charged lead clusters. With this assumption, the dianion clusters have been traced down to Pb212 -, whereas the smallest size for the direct observation was as high as n =28 .

  14. A New Approach to Identify High Burnout Medical Staffs by Kernel K-Means Cluster Analysis in a Regional Teaching Hospital in Taiwan

    PubMed Central

    Lee, Yii-Ching; Huang, Shian-Chang; Huang, Chih-Hsuan; Wu, Hsin-Hung

    2016-01-01

    This study uses kernel k-means cluster analysis to identify medical staffs with high burnout. The data collected in October to November 2014 are from the emotional exhaustion dimension of the Chinese version of Safety Attitudes Questionnaire in a regional teaching hospital in Taiwan. The number of effective questionnaires including the entire staffs such as physicians, nurses, technicians, pharmacists, medical administrators, and respiratory therapists is 680. The results show that 8 clusters are generated by kernel k-means method. Employees in clusters 1, 4, and 5 are relatively in good conditions, whereas employees in clusters 2, 3, 6, 7, and 8 need to be closely monitored from time to time because they have relatively higher degree of burnout. When employees with higher degree of burnout are identified, the hospital management can take actions to improve the resilience, reduce the potential medical errors, and, eventually, enhance the patient safety. This study also suggests that the hospital management needs to keep track of medical staffs’ fatigue conditions and provide timely assistance for burnout recovery through employee assistance programs, mindfulness-based stress reduction programs, positivity currency buildup, and forming appreciative inquiry groups. PMID:27895218

  15. A New Approach to Identify High Burnout Medical Staffs by Kernel K-Means Cluster Analysis in a Regional Teaching Hospital in Taiwan.

    PubMed

    Lee, Yii-Ching; Huang, Shian-Chang; Huang, Chih-Hsuan; Wu, Hsin-Hung

    2016-01-01

    This study uses kernel k-means cluster analysis to identify medical staffs with high burnout. The data collected in October to November 2014 are from the emotional exhaustion dimension of the Chinese version of Safety Attitudes Questionnaire in a regional teaching hospital in Taiwan. The number of effective questionnaires including the entire staffs such as physicians, nurses, technicians, pharmacists, medical administrators, and respiratory therapists is 680. The results show that 8 clusters are generated by kernel k-means method. Employees in clusters 1, 4, and 5 are relatively in good conditions, whereas employees in clusters 2, 3, 6, 7, and 8 need to be closely monitored from time to time because they have relatively higher degree of burnout. When employees with higher degree of burnout are identified, the hospital management can take actions to improve the resilience, reduce the potential medical errors, and, eventually, enhance the patient safety. This study also suggests that the hospital management needs to keep track of medical staffs' fatigue conditions and provide timely assistance for burnout recovery through employee assistance programs, mindfulness-based stress reduction programs, positivity currency buildup, and forming appreciative inquiry groups. © The Author(s) 2016.

  16. Abelian non-global logarithms from soft gluon clustering

    NASA Astrophysics Data System (ADS)

    Kelley, Randall; Walsh, Jonathan R.; Zuberi, Saba

    2012-09-01

    Most recombination-style jet algorithms cluster soft gluons in a complex way. This leads to previously identified correlations in the soft gluon phase space and introduces logarithmic corrections to jet cross sections, which are known as clustering logarithms. The leading Abelian clustering logarithms occur at least at next-to leading logarithm (NLL) in the exponent of the distribution. Using the framework of Soft Collinear Effective Theory (SCET), we show that new clustering effects contributing at NLL arise at each order. While numerical resummation of clustering logs is possible, it is unlikely that they can be analytically resummed to NLL. Clustering logarithms make the anti-kT algorithm theoretically preferred, for which they are power suppressed. They can arise in Abelian and non-Abelian terms, and we calculate the Abelian clustering logarithms at O ( {α_s^2} ) for the jet mass distribution using the Cambridge/Aachen and kT algorithms, including jet radius dependence, which extends previous results. We find that clustering logarithms can be naturally thought of as a class of non-global logarithms, which have traditionally been tied to non-Abelian correlations in soft gluon emission.

  17. Time-resolved explosion of intense-laser-heated clusters.

    PubMed

    Kim, K Y; Alexeev, I; Parra, E; Milchberg, H M

    2003-01-17

    We investigate the femtosecond explosive dynamics of intense laser-heated argon clusters by measuring the cluster complex transient polarizability. The time evolution of the polarizability is characteristic of competition in the optical response between supercritical and subcritical density regions of the expanding cluster. The results are consistent with time-resolved Rayleigh scattering measurements, and bear out the predictions of a recent laser-cluster interaction model [H. M. Milchberg, S. J. McNaught, and E. Parra, Phys. Rev. E 64, 056402 (2001)

  18. Star Formation in Nearby Clusters (SFiNCs)

    NASA Astrophysics Data System (ADS)

    Getman, Konstantin

    Most stars form in clusters that rapidly disperse, yet we have a poor understanding of the processes of cluster formation and early evolution. Do clusters form `top-down', rapidly in a dense molecular cloud core? Or, since clouds are turbulent, do clusters form `bottomup' by merging subclusters produced in small kinematically-distinct molecular structures? Do clusters principally form in elongated molecular structures such as Infrared Dark Clouds and Herschel filaments? One of the central reasons for slow progress in resolving these questions is the lack of homogeneous and reliable census of stellar members (both disk-bearing and disk-free) for a wide range of star forming environments. To address these issues we are now completing our major effort, called MYStIX (Massive Young Star-Forming Complex Study in Infrared and X-ray). It combines the Chandra archive with UKIRT+2MASS near-infrared and Spitzer mid-infrared surveys to identify young stellar objects in a wide range of evolutionary stages, from protostars to disk-free pre-main sequence stars, in 20 star forming regions at distances from 0.4 to 3.6 kpc. Each MYStIX region was chosen to have a rich OB-dominated cluster. Started in 2009 with NASA/ADAP and NSF funding, MYStIX has emerged with 8 technical/catalog and the first 4 of a series of science papers (http://astro.psu.edu/mystix). Early MYStIX results include: demonstration of diverse morphologies of young clusters from simple ellipsoids to elongated, clumpy substructures; demonstration of spatio-age gradients across star formation regions; the discovery of core-halo age gradients within two rich nearby MYStIX clusters; and the discovery of important astrophysically empirical correlations among different subcluster properties such as age, absorption, core radius, central stellar density, and total intrinsic population. The early MYStIX result provide new observational evidence for subcluster merging and cluster expansion following gas dissipation. We

  19. Uniform deposition of size-selected clusters using Lissajous scanning

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Beniya, Atsushi; Watanabe, Yoshihide, E-mail: e0827@mosk.tytlabs.co.jp; Hirata, Hirohito

    2016-05-15

    Size-selected clusters can be deposited on the surface using size-selected cluster ion beams. However, because of the cross-sectional intensity distribution of the ion beam, it is difficult to define the coverage of the deposited clusters. The aggregation probability of the cluster depends on coverage, whereas cluster size on the surface depends on the position, despite the size-selected clusters are deposited. It is crucial, therefore, to deposit clusters uniformly on the surface. In this study, size-selected clusters were deposited uniformly on surfaces by scanning the cluster ions in the form of Lissajous pattern. Two sets of deflector electrodes set in orthogonalmore » directions were placed in front of the sample surface. Triangular waves were applied to the electrodes with an irrational frequency ratio to ensure that the ion trajectory filled the sample surface. The advantages of this method are simplicity and low cost of setup compared with raster scanning method. The authors further investigated CO adsorption on size-selected Pt{sub n} (n = 7, 15, 20) clusters uniformly deposited on the Al{sub 2}O{sub 3}/NiAl(110) surface and demonstrated the importance of uniform deposition.« less

  20. The Elephant Trunk Nebula and the Trumpler 37 cluster: contribution of triggered star formation to the total population of an H II region

    NASA Astrophysics Data System (ADS)

    Getman, Konstantin V.; Feigelson, Eric D.; Sicilia-Aguilar, Aurora; Broos, Patrick S.; Kuhn, Michael A.; Garmire, Gordon P.

    2012-11-01

    Rich young stellar clusters produce H ii regions whose expansion into the nearby molecular cloud is thought to trigger the formation of new stars. However, the importance of this mode of star formation is uncertain. This investigation seeks to quantify triggered star formation (TSF) in IC 1396A (aka the Elephant Trunk Nebula), a bright-rimmed cloud (BRC) on the periphery of the nearby giant H ii region IC 1396 produced by the Trumpler 37 cluster. X-ray selection of young stars from Chandra X-ray Observatory data is combined with existing optical and infrared surveys to give a more complete census of the TSF population. Over 250 young stars in and around IC 1396A are identified; this doubles the previously known population. A spatio-temporal gradient of stars from the IC 1396A cloud towards the primary ionizing star HD 206267 is found. We argue that the TSF mechanism in IC 1396A is a radiation-driven implosion process persisting over several million years. Analysis of the X-ray luminosity and initial mass functions indicates that >140 stars down to 0.1 M⊙ were formed by TSF. Considering other BRCs in the IC 1396 H ii region, we estimate the TSF contribution for the entire H ii region exceeds 14-25 per cent today, and may be higher over the lifetime of the H ii region. Such triggering on the periphery of H ii regions may be a significant mode of star formation in the Galaxy.

  1. Two haplotype clusters of Echinococcus granulosus sensu stricto in northern Iraq (Kurdistan region) support the hypothesis of a parasite cradle in the Middle East.

    PubMed

    Hassan, Zuber Ismael; Meerkhan, Azad Abdullah; Boufana, Belgees; Hama, Abdullah A; Ahmed, Bayram Dawod; Mero, Wijdan Mohammed Salih; Orsten, Serra; Interisano, Maria; Pozio, Edoardo; Casulli, Adriano

    2017-08-01

    Human cystic echinococcosis (CE) caused by Echinococcus granulosus s.s. is a major public health problem in Iraqi Kurdistan with a reported surgical incidence of 6.3 per 100,000 Arbil inhabitants. A total of 125 Echinococcus isolates retrieved from sheep, goats and cattle were used in this study. Our aim was to determine species/genotypes infecting livestock in Iraqi Kurdistan and examine intraspecific variation and population structure of Echinococcus granulosus s.s. in this region and relate it to that of other regions worldwide. Using nucleotide sequences of the mitochondrial cytochrome c oxidase subunit 1 (cox 1) we identified E. granulosus s.s. as the cause of hydatidosis in all examined animals. The haplotype network displayed a double-clustered topology with two main E. granulosus s.s. haplotypes, (KU05) and (KU33). The 'founder' haplotype (KU05) confirmed the presence of a common lineage of non-genetically differentiated populations as inferred by the low non-significant fixation index values. Overall diversity and neutrality indices indicated demographic expansion. We used E. granulosus s.s. nucleotide sequences from GenBank to draw haplotype networks for the Middle East (Iran, Jordan and Turkey), Europe (Albania, Greece, Italy, Romania and Spain), China, Mongolia, Russia, South America (Argentina, Brazil, Chile and Mexico) and Tunisia. Networks with two haplotype clusters like that reported here for Iraqi Kurdistan were seen for the Middle East, Europe, Mongolia, Russia and Tunisia using both 827bp and 1609bp cox1 nucleotide sequences, whereas a star-like network was observed for China and South America. We hypothesize that the double clustering seen at what is generally assumed to be the cradle of domestication may have emerged independently and dispersed from the Middle East to other regions and that haplotype (KU33) may be the main haplotype within a second cluster in the Middle East from where it has spread into Europe, Mongolia, Russia and North

  2. Collisions in Compact Star Clusters.

    NASA Astrophysics Data System (ADS)

    Portegies Zwart, S. F.

    The high stellar densities in young compact star clusters, such as the star cluster R136 in the 30 Doradus region, may lead to a large number of stellar collisions. Such collisions were recently found to be much more frequent than previous estimates. The number of collisions scales with the number of stars for clusters with the same initial relaxation time. These collisions take place in a few million years. The collision products may finally collapse into massive black holes. The fraction of the total mass in the star cluster which ends up in a single massive object scales with the total mass of the cluster and its relaxation time. This mass fraction is rather constant, within a factor two or so. Wild extrapolation from the relatively small masses of the studied systems to the cores of galactic nuclei may indicate that the massive black holes in these systems have formed in a similar way.

  3. The major resistance gene cluster in lettuce is highly duplicated and spans several megabases.

    PubMed Central

    Meyers, B C; Chin, D B; Shen, K A; Sivaramakrishnan, S; Lavelle, D O; Zhang, Z; Michelmore, R W

    1998-01-01

    At least 10 Dm genes conferring resistance to the oomycete downy mildew fungus Bremia lactucae map to the major resistance cluster in lettuce. We investigated the structure of this cluster in the lettuce cultivar Diana, which contains Dm3. A deletion breakpoint map of the chromosomal region flanking Dm3 was saturated with a variety of molecular markers. Several of these markers are components of a family of resistance gene candidates (RGC2) that encode a nucleotide binding site and a leucine-rich repeat region. These motifs are characteristic of plant disease resistance genes. Bacterial artificial chromosome clones were identified by using duplicated restriction fragment length polymorphism markers from the region, including the nucleotide binding site-encoding region of RGC2. Twenty-two distinct members of the RGC2 family were characterized from the bacterial artificial chromosomes; at least two additional family members exist. The RGC2 family is highly divergent; the nucleotide identity was as low as 53% between the most distantly related copies. These RGC2 genes span at least 3.5 Mb. Eighteen members were mapped on the deletion breakpoint map. A comparison between the phylogenetic and physical relationships of these sequences demonstrated that closely related copies are physically separated from one another and indicated that complex rearrangements have shaped this region. Analysis of low-copy genomic sequences detected no genes, including RGC2, in the Dm3 region, other than sequences related to retrotransposons and transposable elements. The related but divergent family of RGC2 genes may act as a resource for the generation of new resistance phenotypes through infrequent recombination or unequal crossing over. PMID:9811791

  4. Detecting space-time disease clusters with arbitrary shapes and sizes using a co-clustering approach.

    PubMed

    Ullah, Sami; Daud, Hanita; Dass, Sarat C; Khan, Habib Nawaz; Khalil, Alamgir

    2017-11-06

    Ability to detect potential space-time clusters in spatio-temporal data on disease occurrences is necessary for conducting surveillance and implementing disease prevention policies. Most existing techniques use geometrically shaped (circular, elliptical or square) scanning windows to discover disease clusters. In certain situations, where the disease occurrences tend to cluster in very irregularly shaped areas, these algorithms are not feasible in practise for the detection of space-time clusters. To address this problem, a new algorithm is proposed, which uses a co-clustering strategy to detect prospective and retrospective space-time disease clusters with no restriction on shape and size. The proposed method detects space-time disease clusters by tracking the changes in space-time occurrence structure instead of an in-depth search over space. This method was utilised to detect potential clusters in the annual and monthly malaria data in Khyber Pakhtunkhwa Province, Pakistan from 2012 to 2016 visualising the results on a heat map. The results of the annual data analysis showed that the most likely hotspot emerged in three sub-regions in the years 2013-2014. The most likely hotspots in monthly data appeared in the month of July to October in each year and showed a strong periodic trend.

  5. Effects of radiation and turbulence on the diabatic heating and water budget of the stratiform region of a tropical cloud cluster

    NASA Technical Reports Server (NTRS)

    Churchill, Dean D.; Houze, Robert A., Jr.

    1991-01-01

    A twi-dimensional kinematic model has been used to diagnose the thermodynamic, water vapor, and hydrometeor fields of the stratiform clouds associated with a mesoscale tropical cloud cluster. The model incorporates ice- and water-cloud microphysics, visible and infrared radiation, and convective adjustment. It is intended to determine the relative contributions of radiation, mycrophysics, and turbulence to diabatic heating, and the effects that radiation has on the water budget of the cluster in the absence of dynamical interactions. The model has been initialized with thermodynamic fields and wind velocities diagnosed from a GATE tropical squall line. It is found that radiation does not directly affect the water budget of the stratiform region, and any radiative effect on hydrometeors must involve interaction with dynamics.

  6. Microbial community development in a dynamic gut model is reproducible, colon region specific, and selective for Bacteroidetes and Clostridium cluster IX.

    PubMed

    Van den Abbeele, Pieter; Grootaert, Charlotte; Marzorati, Massimo; Possemiers, Sam; Verstraete, Willy; Gérard, Philippe; Rabot, Sylvie; Bruneau, Aurélia; El Aidy, Sahar; Derrien, Muriel; Zoetendal, Erwin; Kleerebezem, Michiel; Smidt, Hauke; Van de Wiele, Tom

    2010-08-01

    Dynamic, multicompartment in vitro gastrointestinal simulators are often used to monitor gut microbial dynamics and activity. These reactors need to harbor a microbial community that is stable upon inoculation, colon region specific, and relevant to in vivo conditions. Together with the reproducibility of the colonization process, these criteria are often overlooked when the modulatory properties from different treatments are compared. We therefore investigated the microbial colonization process in two identical simulators of the human intestinal microbial ecosystem (SHIME), simultaneously inoculated with the same human fecal microbiota with a high-resolution phylogenetic microarray: the human intestinal tract chip (HITChip). Following inoculation of the in vitro colon compartments, microbial community composition reached steady state after 2 weeks, whereas 3 weeks were required to reach functional stability. This dynamic colonization process was reproducible in both SHIME units and resulted in highly diverse microbial communities which were colon region specific, with the proximal regions harboring saccharolytic microbes (e.g., Bacteroides spp. and Eubacterium spp.) and the distal regions harboring mucin-degrading microbes (e.g., Akkermansia spp.). Importantly, the shift from an in vivo to an in vitro environment resulted in an increased Bacteroidetes/Firmicutes ratio, whereas Clostridium cluster IX (propionate producers) was enriched compared to clusters IV and XIVa (butyrate producers). This was supported by proportionally higher in vitro propionate concentrations. In conclusion, high-resolution analysis of in vitro-cultured gut microbiota offers new insight on the microbial colonization process and indicates the importance of digestive parameters that may be crucial in the development of new in vitro models.

  7. Intra-cluster Globular Clusters in a Simulated Galaxy Cluster

    NASA Astrophysics Data System (ADS)

    Ramos-Almendares, Felipe; Abadi, Mario; Muriel, Hernán; Coenda, Valeria

    2018-01-01

    Using a cosmological dark matter simulation of a galaxy-cluster halo, we follow the temporal evolution of its globular cluster population. To mimic the red and blue globular cluster populations, we select at high redshift (z∼ 1) two sets of particles from individual galactic halos constrained by the fact that, at redshift z = 0, they have density profiles similar to observed ones. At redshift z = 0, approximately 60% of our selected globular clusters were removed from their original halos building up the intra-cluster globular cluster population, while the remaining 40% are still gravitationally bound to their original galactic halos. As the blue population is more extended than the red one, the intra-cluster globular cluster population is dominated by blue globular clusters, with a relative fraction that grows from 60% at redshift z = 0 up to 83% for redshift z∼ 2. In agreement with observational results for the Virgo galaxy cluster, the blue intra-cluster globular cluster population is more spatially extended than the red one, pointing to a tidally disrupted origin.

  8. Neck circumference and clustered cardiovascular risk factors in children and adolescents: cross-sectional study

    PubMed Central

    Castro-Piñero, José; Delgado-Alfonso, Alvaro; Gracia-Marco, Luis; Gómez-Martínez, Sonia; Esteban-Cornejo, Irene; Veiga, Oscar L; Marcos, Ascensión; Segura-Jiménez, Víctor

    2017-01-01

    Objective Early detection of cardiovascular disease (CVD) risk factors, such as obesity, is crucial to prevent adverse long-term effects on individuals’ health. Therefore, the aims were: (1) to explore the robustness of neck circumference (NC) as a predictor of CVD and examine its association with numerous anthropometric and body composition indices and (2) to release sex and age-specific NC cut-off values to classify youths as overweight/obese. Design Cross-sectional study. Setting 23 primary schools and 17 secondary schools from Spain. Participants 2198 students (1060 girls), grades 1–4 and 7–10. Measures Pubertal development, anthropometric and body composition indices, systolic and diastolic blood pressure (SBP and DBP, respectively), cardiorespiratory fitness, blood sampling triglycerides (TG), total cholesterol (TC), high-density lipoprotein cholesterol (HDL-c), low-density lipoprotein cholesterol (LDL-c), glucose and inflammatory markers. Homoeostasis model assessment (HOMA-IR) and cluster of CVD risk factors were calculated. Results NC was positively correlated with all anthropometric and body composition indices. NC was negatively associated with maximum oxygen consumption (R2=0.231, p<0.001 for boys; R2=0.018, p<0.001 for girls) and positively associated with SBP, DBP, TC/HDL-c, TG, HOMA, complement factors C-3 and C-4, leptin, adiponectin and clustered CVD risk factor in both sexes (R2 from 0.035 to 0.353, p<0.01 for boys; R2 from 0.024 to 0.215, p<0.001 for girls). Moreover, NC was positively associated with serum C reactive protein, LDL-c and visfatin only in boys (R2 from 0.013 to 0.107, p<0.05). Conclusion NC is a simple, low-cost and practical screening tool of excess of upper body obesity and CVD risk factors in children and adolescents. Paediatricians can easily use it as a screening tool for overweight/obesity in children and adolescents. For this purpose, sex and age-specific thresholds to classify children and adolescents as normal weight

  9. Word-initial rhotic clusters in typically developing children: European Portuguese.

    PubMed

    Ramalho, Ana Margarida; Freitas, M João

    2018-01-01

    Rhotic clusters are complex structures segmentally and prosodically and are frequently one of the last structures acquired by Portuguese-speaking children. This paper describes cross-sectional data for word-initial (WI) rhotic tap clusters in typically developing 3-4- and 5-year-olds in Portugal. Additional information is provided on WI /l/ as a singleton and in clusters. A native speaker audio-recorded and transcribed single words in a story-telling task. Results for WI rhotic clusters show an age effect consistent with previous research on European Portuguese. Singleton /l/ was in advance of /l/-clusters as expected, but the tap clusters were in advance of the /l/-clusters, possibly reflecting the velarized characteristics of the lateral. The prosodic variables word stress and word length were relevant for the WI rhotic clusters: shorter words and stressed syllables showed higher accuracy. Finally, mismatches ('errors') mainly reflected negative structural constraints (deletion of C2 and epenthesis) rather than segmental constraints (substitutions).

  10. Cross Layered Multi-Meshed Tree Scheme for Cognitive Networks

    DTIC Science & Technology

    2011-06-01

    Meshed Tree Routing protocol wireless ad hoc networks ,” Second IEEE International Workshop on Enabling Technologies and Standards for Wireless Mesh ...and Sensor Networks , 2004 43. Chen G.; Stojmenovic I., “Clustering and routing in mobile wireless networks ,” Technical Report TR-99-05, SITE, June...Cross-layer optimization, intra-cluster routing , packet forwarding, inter-cluster routing , mesh network communications,

  11. Statistical Study in the mid-altitude cusp region: wave and particle data comparison using a normalized cusp crossing duration

    NASA Astrophysics Data System (ADS)

    Grison, B.; Escoubet, C. P.; Pitout, F.; Cornilleau-Wehrlin, N.; Dandouras, I.; Lucek, E.

    2009-04-01

    In the mid altitude cusp region the DC magnetic field presents a diamagnetic cavity due to intense ion earthward flux coming from the magnetosheath. A strong ultra low frequency (ULF) magnetic activity is also commonly observed in this region. Most of the mid altitude cusp statistical studies have focused on the location of the cusp and its dependence and response to solar wind, interplanetary magnetic field, dipole tilt angle parameters. In our study we use the database build by Pitout et al. (2006) in order to study the link of wave power in the ULF range (0.35-10Hz) measured by STAFF SC instrument with the ion plasma properties as measured by CIS (and CODIF) instrument as well as the diamagnetic cavity in the mid-altitude cusp region with FGM data. To compare the different crossings we don`t use the cusp position and dynamics but we use a normalized cusp crossing duration that permits to easily average the properties over a large number of crossings. As usual in the cusp, it is particularly relevant to sort the crossings by the corresponding interplanetary magnetic field (IMF) orientation in order to analyse the results. In particular we try to find out what is the most relevant parameter to link the strong wave activity with. The global statistic confirms previous single case observations that have noticed a simultaneity between ion injections and wave activity enhancements. We will also present results concerning other ion parameters and the diamagnetic cavity observed in the mid altitude cusp region.

  12. Spatial cluster detection using dynamic programming.

    PubMed

    Sverchkov, Yuriy; Jiang, Xia; Cooper, Gregory F

    2012-03-25

    The task of spatial cluster detection involves finding spatial regions where some property deviates from the norm or the expected value. In a probabilistic setting this task can be expressed as finding a region where some event is significantly more likely than usual. Spatial cluster detection is of interest in fields such as biosurveillance, mining of astronomical data, military surveillance, and analysis of fMRI images. In almost all such applications we are interested both in the question of whether a cluster exists in the data, and if it exists, we are interested in finding the most accurate characterization of the cluster. We present a general dynamic programming algorithm for grid-based spatial cluster detection. The algorithm can be used for both Bayesian maximum a-posteriori (MAP) estimation of the most likely spatial distribution of clusters and Bayesian model averaging over a large space of spatial cluster distributions to compute the posterior probability of an unusual spatial clustering. The algorithm is explained and evaluated in the context of a biosurveillance application, specifically the detection and identification of Influenza outbreaks based on emergency department visits. A relatively simple underlying model is constructed for the purpose of evaluating the algorithm, and the algorithm is evaluated using the model and semi-synthetic test data. When compared to baseline methods, tests indicate that the new algorithm can improve MAP estimates under certain conditions: the greedy algorithm we compared our method to was found to be more sensitive to smaller outbreaks, while as the size of the outbreaks increases, in terms of area affected and proportion of individuals affected, our method overtakes the greedy algorithm in spatial precision and recall. The new algorithm performs on-par with baseline methods in the task of Bayesian model averaging. We conclude that the dynamic programming algorithm performs on-par with other available methods for

  13. Spatial cluster detection using dynamic programming

    PubMed Central

    2012-01-01

    Background The task of spatial cluster detection involves finding spatial regions where some property deviates from the norm or the expected value. In a probabilistic setting this task can be expressed as finding a region where some event is significantly more likely than usual. Spatial cluster detection is of interest in fields such as biosurveillance, mining of astronomical data, military surveillance, and analysis of fMRI images. In almost all such applications we are interested both in the question of whether a cluster exists in the data, and if it exists, we are interested in finding the most accurate characterization of the cluster. Methods We present a general dynamic programming algorithm for grid-based spatial cluster detection. The algorithm can be used for both Bayesian maximum a-posteriori (MAP) estimation of the most likely spatial distribution of clusters and Bayesian model averaging over a large space of spatial cluster distributions to compute the posterior probability of an unusual spatial clustering. The algorithm is explained and evaluated in the context of a biosurveillance application, specifically the detection and identification of Influenza outbreaks based on emergency department visits. A relatively simple underlying model is constructed for the purpose of evaluating the algorithm, and the algorithm is evaluated using the model and semi-synthetic test data. Results When compared to baseline methods, tests indicate that the new algorithm can improve MAP estimates under certain conditions: the greedy algorithm we compared our method to was found to be more sensitive to smaller outbreaks, while as the size of the outbreaks increases, in terms of area affected and proportion of individuals affected, our method overtakes the greedy algorithm in spatial precision and recall. The new algorithm performs on-par with baseline methods in the task of Bayesian model averaging. Conclusions We conclude that the dynamic programming algorithm performs on

  14. The Effect of Mergers on Galaxy Cluster Mass Estimates

    NASA Astrophysics Data System (ADS)

    Johnson, Ryan E.; Zuhone, John A.; Thorsen, Tessa; Hinds, Andre

    2015-08-01

    At vertices within the filamentary structure that describes the universal matter distribution, clusters of galaxies grow hierarchically through merging with other clusters. As such, the most massive galaxy clusters should have experienced many such mergers in their histories. Though we cannot see them evolve over time, these mergers leave lasting, measurable effects in the cluster galaxies' phase space. By simulating several different galaxy cluster mergers here, we examine how the cluster galaxies kinematics are altered as a result of these mergers. Further, we also examine the effect of our line of sight viewing angle with respect to the merger axis. In projecting the 6-dimensional galaxy phase space onto a 3-dimensional plane, we are able to simulate how these clusters might actually appear to optical redshift surveys. We find that for those optical cluster statistics which are most often used as a proxy for the cluster mass (variants of σv), the uncertainty due to an inprecise or unknown line of sight may alter the derived cluster masses moreso than the kinematic disturbance of the merger itself. Finally, by examining these, and several other clustering statistics, we find that significant events (such as pericentric crossings) are identifiable over a range of merger initial conditions and from many different lines of sight.

  15. Neck formation and deformation effects in a preformed cluster model of exotic cluster decays

    NASA Astrophysics Data System (ADS)

    Kumar, Satish; Gupta, Raj K.

    1997-01-01

    Using the nuclear proximity approach and the two center nuclear shape parametrization, the interaction potential between two deformed and pole-to-pole oriented nuclei forming a necked configuration in the overlap region is calculated and its role is studied for the cluster decay half-lives. The barrier is found to move to a larger relative separation, with its proximity minimum lying in the neighborhood of the Q value of decay and its height and width reduced considerably. For cluster decay calculations in the preformed cluster model of Malik and Gupta, due to deformations and orientations of nuclei, the (empirical) preformation factor is found to get reduced considerably and agrees nicely with other model calculations known to be successful for their predictions of cluster decay half-lives. Comparison with the earlier case of nuclei treated as spheres suggests that the effects of both deformations and neck formation get compensated by choosing the position of cluster preformation and the inner classical turning point for penetrability calculations at the touching configuration of spherical nuclei.

  16. Sample size calculations for stepped wedge and cluster randomised trials: a unified approach

    PubMed Central

    Hemming, Karla; Taljaard, Monica

    2016-01-01

    Objectives To clarify and illustrate sample size calculations for the cross-sectional stepped wedge cluster randomized trial (SW-CRT) and to present a simple approach for comparing the efficiencies of competing designs within a unified framework. Study Design and Setting We summarize design effects for the SW-CRT, the parallel cluster randomized trial (CRT), and the parallel cluster randomized trial with before and after observations (CRT-BA), assuming cross-sectional samples are selected over time. We present new formulas that enable trialists to determine the required cluster size for a given number of clusters. We illustrate by example how to implement the presented design effects and give practical guidance on the design of stepped wedge studies. Results For a fixed total cluster size, the choice of study design that provides the greatest power depends on the intracluster correlation coefficient (ICC) and the cluster size. When the ICC is small, the CRT tends to be more efficient; when the ICC is large, the SW-CRT tends to be more efficient and can serve as an alternative design when the CRT is an infeasible design. Conclusion Our unified approach allows trialists to easily compare the efficiencies of three competing designs to inform the decision about the most efficient design in a given scenario. PMID:26344808

  17. Dynamical evolution and spatial mixing of multiple population globular clusters

    NASA Astrophysics Data System (ADS)

    Vesperini, Enrico; McMillan, Stephen L. W.; D'Antona, Francesca; D'Ercole, Annibale

    2013-03-01

    Numerous spectroscopic and photometric observational studies have provided strong evidence for the widespread presence of multiple stellar populations in globular clusters. In this paper, we study the long-term dynamical evolution of multiple population clusters, focusing on the evolution of the spatial distributions of the first- (FG) and second-generation (SG) stars. In previous studies, we have suggested that SG stars formed from the ejecta of FG AGB stars are expected initially to be concentrated in the cluster inner regions. Here, by means of N-body simulations, we explore the time-scales and the dynamics of the spatial mixing of the FG and the SG populations and their dependence on the SG initial concentration. Our simulations show that, as the evolution proceeds, the radial profile of the SG/FG number ratio, NSG/NFG, is characterized by three regions: (1) a flat inner part; (2) a declining part in which FG stars are increasingly dominant and (3) an outer region where the NSG/NFG profile flattens again (the NSG/NFG profile may rise slightly again in the outermost cluster regions). Until mixing is complete and the NSG/NFG profile is flat over the entire cluster, the radial variation of NSG/NFG implies that the fraction of SG stars determined by observations covering a limited range of radial distances is not, in general, equal to the SG global fraction, (NSG/NFG)glob. The distance at which NSG/NFG equals (NSG/NFG)glob is approximately between 1 and 2 cluster half-mass radii. The time-scale for complete mixing depends on the SG initial concentration, but in all cases complete mixing is expected only for clusters in advanced evolutionary phases, having lost at least 60-70 per cent of their mass due to two-body relaxation (in addition to the early FG loss due to the cluster expansion triggered by SNII ejecta and gas expulsion).The results of our simulations suggest that in many Galactic globular clusters the SG should still be more spatially concentrated than the

  18. Fibers in the NGC 1333 proto-cluster

    NASA Astrophysics Data System (ADS)

    Hacar, A.; Tafalla, M.; Alves, J.

    2017-10-01

    Are the initial conditions for clustered star formation the same as for non-clustered star formation? To investigate the initial gas properties in young proto-clusters we carried out a comprehensive and high-sensitivity study of the internal structure, density, temperature, and kinematics of the dense gas content of the NGC 1333 region in Perseus, one of the nearest and best studied embedded clusters. The analysis of the gas velocities in the position-position-velocity space reveals an intricate underlying gas organization both in space and velocity. We identified a total of 14 velocity-coherent, (tran-)sonic structures within NGC 1333, with similar physical and kinematic properties than those quiescent, star-forming (aka fertile) fibers previously identified in low-mass star-forming clouds. These fibers are arranged in a complex spatial network, build-up the observed total column density, and contain the dense cores and protostars in this cloud. Our results demonstrate that the presence of fibers is not restricted to low-mass clouds but can be extended to regions of increasing mass and complexity. We propose that the observational dichotomy between clustered and non-clustered star-forming regions might be naturally explained by the distinct spatial density of fertile fibers in these environments. Based on observations carried out under project number 169-11 with the IRAM 30 m Telescope. IRAM is supported by INSU/CNRS (France), MPG (Germany) and IGN (Spain).Based on observations with the 100-m telescope of the MPIfR (Max-Planck-Institut für Radioastronomie) at Effelsberg.Molecular line observations (spectral cubes) are only available at the CDS via anonymous ftp to http://cdsarc.u-strasbg.fr (http://130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/606/A123

  19. Nursing home care quality: a cluster analysis.

    PubMed

    Grøndahl, Vigdis Abrahamsen; Fagerli, Liv Berit

    2017-02-13

    Purpose The purpose of this paper is to explore potential differences in how nursing home residents rate care quality and to explore cluster characteristics. Design/methodology/approach A cross-sectional design was used, with one questionnaire including questions from quality from patients' perspective and Big Five personality traits, together with questions related to socio-demographic aspects and health condition. Residents ( n=103) from four Norwegian nursing homes participated (74.1 per cent response rate). Hierarchical cluster analysis identified clusters with respect to care quality perceptions. χ 2 tests and one-way between-groups ANOVA were performed to characterise the clusters ( p<0.05). Findings Two clusters were identified; Cluster 1 residents (28.2 per cent) had the best care quality perceptions and Cluster 2 (67.0 per cent) had the worst perceptions. The clusters were statistically significant and characterised by personal-related conditions: gender, psychological well-being, preferences, admission, satisfaction with staying in the nursing home, emotional stability and agreeableness, and by external objective care conditions: healthcare personnel and registered nurses. Research limitations/implications Residents assessed as having no cognitive impairments were included, thus excluding the largest group. By choosing questionnaire design and structured interviews, the number able to participate may increase. Practical implications Findings may provide healthcare personnel and managers with increased knowledge on which to develop strategies to improve specific care quality perceptions. Originality/value Cluster analysis can be an effective tool for differentiating between nursing homes residents' care quality perceptions.

  20. Personal values, marketing attitudes and nutrition trust are associated with patronage of convenience food outlets in the Asia-Pacific region: a cross-sectional study.

    PubMed

    De Jong, Breanna; Worsley, Anthony; Wang, Wei Chun; Sarmugam, Rani; Pham, Quynh; Februhartanty, Judhiastuty; Ridley, Stacey

    2017-02-16

    An online cross-sectional survey examined the relationships between the demographic characteristics, personal values, trust in sources of nutrition information and the use of convenience food outlets among middle-class household food providers in the Asia-Pacific region. The survey was administered to 3945 household food providers in Melbourne, Singapore, Shanghai, Vietnam and Indonesia in late 2013. Information about demographics, personal values, trust in sources of nutrition information and use of convenience food outlets was elicited. Exploratory factor analysis, two-step clustering and logistic regression were employed. The analyses found that the use of convenience food outlets was positively related to hedonist values and trust in food industry sources of nutrition information. However, lesser use of convenience food outlets and trust in health sources of nutrition information was associated with traditional (community-oriented) values. Further replication and extension of these findings would be useful. However, they suggest that improvements in the quality of foods sold in convenience food outlets combined with stronger regulation of food marketing and long-term food education are required.

  1. Allergen Sensitization Pattern by Sex: A Cluster Analysis in Korea.

    PubMed

    Ohn, Jungyoon; Paik, Seung Hwan; Doh, Eun Jin; Park, Hyun-Sun; Yoon, Hyun-Sun; Cho, Soyun

    2017-12-01

    Allergens tend to sensitize simultaneously. Etiology of this phenomenon has been suggested to be allergen cross-reactivity or concurrent exposure. However, little is known about specific allergen sensitization patterns. To investigate the allergen sensitization characteristics according to gender. Multiple allergen simultaneous test (MAST) is widely used as a screening tool for detecting allergen sensitization in dermatologic clinics. We retrospectively reviewed the medical records of patients with MAST results between 2008 and 2014 in our Department of Dermatology. A cluster analysis was performed to elucidate the allergen-specific immunoglobulin (Ig)E cluster pattern. The results of MAST (39 allergen-specific IgEs) from 4,360 cases were analyzed. By cluster analysis, 39items were grouped into 8 clusters. Each cluster had characteristic features. When compared with female, the male group tended to be sensitized more frequently to all tested allergens, except for fungus allergens cluster. The cluster and comparative analysis results demonstrate that the allergen sensitization is clustered, manifesting allergen similarity or co-exposure. Only the fungus cluster allergens tend to sensitize female group more frequently than male group.

  2. Evolution of auroral acceleration region field-aligned current systems, plasma, and potentials observed by Cluster during substorms

    NASA Astrophysics Data System (ADS)

    Hull, A. J.; Chaston, C. C.; Fillingim, M. O.; Frey, H. U.; Goldstein, M. L.; Bonnell, J. W.; Mozer, F.

    2015-12-01

    The auroral acceleration region is an integral link in the chain of events that transpire during substorms, and the currents, plasma and electric fields undergo significant changes driven by complex dynamical processes deep in the magnetotail. The acceleration processes that occur therein accelerate and heat the plasma that ultimately leads to some of the most intense global substorm auroral displays. Though this region has garnered considerable attention, the temporal evolution of field-aligned current systems, associated acceleration processes, and resultant changes in the plasma constituents that occur during key stages of substorm development remain unclear. In this study we present a survey of Cluster traversals within and just above the auroral acceleration region (≤3 Re altitude) during substorms. Particular emphasis is on the spatial morphology and developmental sequence of auroral acceleration current systems, potentials and plasma constituents, with the aim of identifying controlling factors, and assessing auroral emmission consequences. Exploiting multi-point measurements from Cluster in combination with auroral imaging, we reveal the injection powered, Alfvenic nature of both the substorm onset and expansion of auroral particle acceleration. We show evidence that indicates substorm onsets are characterized by the gross-intensification and filamentation/striation of pre-existing large-scale current systems to smaller/dispersive scale Alfven waves. Such an evolutionary sequence has been suggested in theoretical models or single spacecraft data, but has not been demonstrated or characterized in multispacecraft observations until now. It is also shown how the Alfvenic variations over time may dissipate to form large-scale inverted-V structures characteristic of the quasi-static aurora. These findings suggest that, in addition to playing active roles in driving substorm aurora, inverted-V and Alfvenic acceleration processes are causally linked. Key

  3. Multiscale mutation clustering algorithm identifies pan-cancer mutational clusters associated with pathway-level changes in gene expression

    PubMed Central

    Poole, William; Leinonen, Kalle; Shmulevich, Ilya

    2017-01-01

    Cancer researchers have long recognized that somatic mutations are not uniformly distributed within genes. However, most approaches for identifying cancer mutations focus on either the entire-gene or single amino-acid level. We have bridged these two methodologies with a multiscale mutation clustering algorithm that identifies variable length mutation clusters in cancer genes. We ran our algorithm on 539 genes using the combined mutation data in 23 cancer types from The Cancer Genome Atlas (TCGA) and identified 1295 mutation clusters. The resulting mutation clusters cover a wide range of scales and often overlap with many kinds of protein features including structured domains, phosphorylation sites, and known single nucleotide variants. We statistically associated these multiscale clusters with gene expression and drug response data to illuminate the functional and clinical consequences of mutations in our clusters. Interestingly, we find multiple clusters within individual genes that have differential functional associations: these include PTEN, FUBP1, and CDH1. This methodology has potential implications in identifying protein regions for drug targets, understanding the biological underpinnings of cancer, and personalizing cancer treatments. Toward this end, we have made the mutation clusters and the clustering algorithm available to the public. Clusters and pathway associations can be interactively browsed at m2c.systemsbiology.net. The multiscale mutation clustering algorithm is available at https://github.com/IlyaLab/M2C. PMID:28170390

  4. Multiscale mutation clustering algorithm identifies pan-cancer mutational clusters associated with pathway-level changes in gene expression.

    PubMed

    Poole, William; Leinonen, Kalle; Shmulevich, Ilya; Knijnenburg, Theo A; Bernard, Brady

    2017-02-01

    Cancer researchers have long recognized that somatic mutations are not uniformly distributed within genes. However, most approaches for identifying cancer mutations focus on either the entire-gene or single amino-acid level. We have bridged these two methodologies with a multiscale mutation clustering algorithm that identifies variable length mutation clusters in cancer genes. We ran our algorithm on 539 genes using the combined mutation data in 23 cancer types from The Cancer Genome Atlas (TCGA) and identified 1295 mutation clusters. The resulting mutation clusters cover a wide range of scales and often overlap with many kinds of protein features including structured domains, phosphorylation sites, and known single nucleotide variants. We statistically associated these multiscale clusters with gene expression and drug response data to illuminate the functional and clinical consequences of mutations in our clusters. Interestingly, we find multiple clusters within individual genes that have differential functional associations: these include PTEN, FUBP1, and CDH1. This methodology has potential implications in identifying protein regions for drug targets, understanding the biological underpinnings of cancer, and personalizing cancer treatments. Toward this end, we have made the mutation clusters and the clustering algorithm available to the public. Clusters and pathway associations can be interactively browsed at m2c.systemsbiology.net. The multiscale mutation clustering algorithm is available at https://github.com/IlyaLab/M2C.

  5. Reexamining cluster radioactivity in trans-lead nuclei with consideration of specific density distributions in daughter nuclei and clusters

    NASA Astrophysics Data System (ADS)

    Qian, Yibin; Ren, Zhongzhou; Ni, Dongdong

    2016-08-01

    We further investigate the cluster emission from heavy nuclei beyond the lead region in the framework of the preformed cluster model. The refined cluster-core potential is constructed by the double-folding integral of the density distributions of the daughter nucleus and the emitted cluster, where the radius or the diffuseness parameter in the Fermi density distribution formula is determined according to the available experimental data on the charge radii and the neutron skin thickness. The Schrödinger equation of the cluster-daughter relative motion is then solved within the outgoing Coulomb wave-function boundary conditions to obtain the decay width. It is found that the present decay width of cluster emitters is clearly enhanced as compared to that in the previous case, which involved the fixed parametrization for the density distributions of daughter nuclei and clusters. Among the whole procedure, the nuclear deformation of clusters is also introduced into the calculations, and the degree of its influence on the final decay half-life is checked to some extent. Moreover, the effect from the bubble density distribution of clusters on the final decay width is carefully discussed by using the central depressed distribution.

  6. Kinematics and dynamics of the MKW/AWM poor clusters

    NASA Technical Reports Server (NTRS)

    Beers, Timothy C.; Kriessler, Jeffrey R.; Bird, Christina M.; Huchra, John P.

    1995-01-01

    We report 472 new redshifts for 416 galaxies in the regions of the 23 poor clusters of galaxies originally identified by Morgan, Kayser, and White (MKW), and Albert, White, and Morgan (AWM). Eighteen of the poor clusters now have 10 or more available redshifts within 1.5/h Mpc of the central galaxy; 11 clusters have at least 20 available redshifts. Based on the 21 clusters for which we have sufficient velocity information, the median velocity scale is 336 km/s, a factor of 2 smaller than found for rich clusters. Several of the poor clusters exhibit complex velocity distributions due to the presence of nearby clumps of galaxies. We check on the velocity of the dominant galaxy in each poor cluster relative to the remaining cluster members. Significantly high relative velocities of the dominant galaxy are found in only 4 of 21 poor clusters, 3 of which we suspect are due to contamination of the parent velocity distribution. Several statistical tests indicate that the D/cD galaxies are at the kinematic centers of the parent poor cluster velocity distributions. Mass-to-light ratios for 13 of the 15 poor clusters for which we have the required data are in the range 50 less than or = M/L(sub B(0)) less than or = 200 solar mass/solar luminosity. The complex nature of the regions surrounding many of the poor clusters suggests that these groupings may represent an early epoch of cluster formation. For example, the poor clusters MKW7 and MKWS are shown to be gravitationally bound and likely to merge to form a richer cluster within the next several Gyrs. Eight of the nine other poor clusters for which simple two-body dynamical models can be carried out are consistent with being bound to other clumps in their vicinity. Additional complex systems with more than two gravitationally bound clumps are observed among the poor clusters.

  7. Cluster Ion Spectrometry (CIS) Data Archiving in the CAA

    NASA Astrophysics Data System (ADS)

    Dandouras, I. S.; Barthe, A.; Penou, E.; Brunato, S.; Reme, H.; Kistler, L. M.; Blagau, A.; Facsko, G.; Kronberg, E.; Laakso, H. E.

    2009-12-01

    The Cluster Active Archive (CAA) aims at preserving the four Cluster spacecraft data, so that they are usable in the long-term by the scientific community as well as by the instrument team PIs and Co-Is. This implies that the data are filed together with the descriptive and documentary elements making it possible to select and interpret them. The CIS (Cluster Ion Spectrometry) experiment is a comprehensive ionic plasma spectrometry package onboard the four Cluster spacecraft, capable of obtaining full three-dimensional ion distributions (about 0 to 40 keV/e) with a time resolution of one spacecraft spin (4 sec) and with mass-per-charge composition determination. The CIS package consists of two different instruments, a Hot Ion Analyser (HIA) and a time-of-flight ion Composition Distribution Function (CODIF) analyser. For the archival of the CIS data a multi-level approach has been adopted. The CAA archival includes processed raw data (Level 1 data), moments of the ion distribution functions (Level 2 data), and calibrated high-resolution data in a variety of physical units (Level 3 data). The latter are 3-D ion distribution functions and 2-D pitch-angle distributions. In addition, a software package has been developed to allow the CAA user to interactively calculate partial or total moments of the ion distributions. Instrument cross-calibration has been an important activity in preparing the data for archival. The CIS data archive includes also experiment documentation, graphical products for browsing through the data, and data caveats. In addition, data quality indexes are under preparation, to help the user. Given the complexity of an ion spectrometer, and the variety of its operational modes, each one being optimised for a different magnetospheric region or measurement objective, consultation of the data caveats by the end user will always be a necessary step in the data analysis.

  8. Right Place, Wrong Species: A 20-Year Review of Rabies Virus Cross Species Transmission among Terrestrial Mammals in the United States

    PubMed Central

    Wallace, Ryan M.; Gilbert, Amy; Slate, Dennis; Chipman, Richard; Singh, Amber; Cassie Wedd; Blanton, Jesse D.

    2014-01-01

    Introduction In the continental US, four terrestrial mammalian species are reservoirs for seven antigenic rabies virus variants. Cross species transmission (CST) occurs when a rabies virus variant causes disease in non-reservoir species. Methods This study analyzed national surveillance data for rabies in terrestrial mammals. The CST rate was defined as: number of rabid non-reservoir animals/number of rabid reservoir animals. CST rates were analyzed for trend. Clusters of high CST rate counties were evaluated using space-time scanning statistics. Results The number of counties reporting a raccoon variant CST rate >1.0 increased from 75 in 1992 to 187 in 2011; counties with skunk variant CST rates >1.0 remained unchanged during the same period. As of 2011, for every rabid raccoon reported within the raccoon variant region, there were 0.73 cases of this variant reported in non-reservoir animals. Skunks were the most common non-reservoir animal reported with the raccoon rabies variant. Domestic animals were the most common non-reservoir animal diagnosed with a skunk rabies virus variant (n = 1,601). Cross species transmission rates increased fastest among domestic animals. Conclusions Cross species transmission of rabies virus variants into non-reservoir animals increases the risk of human exposures and threatens current advances toward rabies control. Cross species transmission in raccoon rabies enzootic regions increased dramatically during the study period. Pet owners should vaccinate their dogs and cats to ensure against CST, particularly in regions with active foci of rabies circulation. Clusters of high CST activity represent areas for further study to better understand interspecies disease transmission dynamics. Each CST event has the potential to result in a rabies virus adapted for sustained transmission in a new species; therefore further understanding of the dynamics of CST may help in early detection or prevention of the emergence of new terrestrial

  9. Right place, wrong species: a 20-year review of rabies virus cross species transmission among terrestrial mammals in the United States.

    PubMed

    Wallace, Ryan M; Gilbert, Amy; Slate, Dennis; Chipman, Richard; Singh, Amber; Cassie Wedd; Blanton, Jesse D

    2014-01-01

    In the continental US, four terrestrial mammalian species are reservoirs for seven antigenic rabies virus variants. Cross species transmission (CST) occurs when a rabies virus variant causes disease in non-reservoir species. This study analyzed national surveillance data for rabies in terrestrial mammals. The CST rate was defined as: number of rabid non-reservoir animals/number of rabid reservoir animals. CST rates were analyzed for trend. Clusters of high CST rate counties were evaluated using space-time scanning statistics. The number of counties reporting a raccoon variant CST rate >1.0 increased from 75 in 1992 to 187 in 2011; counties with skunk variant CST rates >1.0 remained unchanged during the same period. As of 2011, for every rabid raccoon reported within the raccoon variant region, there were 0.73 cases of this variant reported in non-reservoir animals. Skunks were the most common non-reservoir animal reported with the raccoon rabies variant. Domestic animals were the most common non-reservoir animal diagnosed with a skunk rabies virus variant (n = 1,601). Cross species transmission rates increased fastest among domestic animals. Cross species transmission of rabies virus variants into non-reservoir animals increases the risk of human exposures and threatens current advances toward rabies control. Cross species transmission in raccoon rabies enzootic regions increased dramatically during the study period. Pet owners should vaccinate their dogs and cats to ensure against CST, particularly in regions with active foci of rabies circulation. Clusters of high CST activity represent areas for further study to better understand interspecies disease transmission dynamics. Each CST event has the potential to result in a rabies virus adapted for sustained transmission in a new species; therefore further understanding of the dynamics of CST may help in early detection or prevention of the emergence of new terrestrial rabies virus variants.

  10. Photoionization of rare gas clusters

    NASA Astrophysics Data System (ADS)

    Zhang, Huaizhen

    angular distribution parameter values of the two-spin-orbit components from Ar 2p clusters are slightly different. When comparing the beta values for Ar between atoms and clusters, we found different results between Ar 3s atoms and clusters, and between Ar 3p atoms and clusters. Argon cluster resonance from surface and bulk were also measured. Furthermore, the angular distribution parameters of Ar cluster photoelectrons and Ar atom photoelectrons in the 3s → np ionization region were obtained.

  11. Deep observation of A2163: studying a new bullet cluster

    NASA Astrophysics Data System (ADS)

    Bourdin, Herve

    2011-10-01

    Exhibiting a clear spatial separation between the gas and dark matter component of a fastly accreted subcluster, the `bullet cluster', 1E 0657-56, has provided us a unique laboratory to investigate the impact of violent cluster mergers on the Intra-Cluster Medium, galaxies and dark matter properties. In recent analyses of X-ray, optical and weak-lensing data, we show that the massive cluster A2163 also exhibits a crossing gas bullet separated from a galaxy and dark matter over-density, and suggest that both A2163 and 1E 0657-56 share a common merging scenario possibly just differing in the time elapsed after the closest cluster encounters. With this deeper XMM observation of A2163, we propose to refine our knowledge of the dynamics and geometry of the on-going subcluster accretion.

  12. Deep near-infrared adaptive-optics observations of a young embedded cluster at the edge of the RCW 41 H II region

    NASA Astrophysics Data System (ADS)

    Neichel, B.; Samal, M. R.; Plana, H.; Zavagno, A.; Bernard, A.; Fusco, T.

    2015-04-01

    Aims: We investigate the star formation activity in a young star forming cluster embedded at the edge of the RCW 41 H ii region. As a complementary goal, we aim to demonstrate the gain provided by wide-field adaptive optics (WFAO) instruments to study young clusters. Methods: We used deep, JHKs images from the newly commissioned Gemini-GeMS/GSAOI instrument, complemented with Spitzer IRAC observations, in order to study the photometric properties of the young stellar cluster. GeMS is a WFAO instrument that delivers almost diffraction-limited images over a field of ~2' across. The exquisite angular resolution allows us to reach a limiting magnitude of J ~ 22 for 98% completeness. The combination of the IRAC photometry with our JHKs catalog is used to build color-color diagrams, and select young stellar object (YSO) candidates. The JHKs photometry is also used in conjunction with pre-main sequence evolutionary models to infer masses and ages. The K-band luminosity function is derived, and then used to build the initial mass function (IMF) of the cluster. Results: We detect the presence of 80 YSO candidates. Those YSOs are used to infer the cluster age, which is found to be in the range 1 to 5 Myr. More precisely, we find that 1/3 of the YSOs are in a range between 3 to 5 Myr, while 2/3 of the YSO are ≤3 Myr. When looking at the spatial distribution of these two populations, we find evidence of a potential age gradient across the field that suggests sequential star formation. We construct the IMF and show that we can sample the mass distribution well into the brown dwarf regime (down to ~0.01 M⊙). The logarithmic mass function rises to peak at ~0.3 M⊙, before turning over and declining into the brown dwarf regime. The total cluster mass derived is estimated to be 78 ± 18 M⊙, while the ratio derived of brown dwarfs to star is 18 ± 5%. When comparing it with other young clusters, we find that the IMF shape of the young cluster embedded within RCW 41 is

  13. Standardized Effect Size Measures for Mediation Analysis in Cluster-Randomized Trials

    ERIC Educational Resources Information Center

    Stapleton, Laura M.; Pituch, Keenan A.; Dion, Eric

    2015-01-01

    This article presents 3 standardized effect size measures to use when sharing results of an analysis of mediation of treatment effects for cluster-randomized trials. The authors discuss 3 examples of mediation analysis (upper-level mediation, cross-level mediation, and cross-level mediation with a contextual effect) with demonstration of the…

  14. Observed intra-cluster correlation coefficients in a cluster survey sample of patient encounters in general practice in Australia

    PubMed Central

    Knox, Stephanie A; Chondros, Patty

    2004-01-01

    Background Cluster sample study designs are cost effective, however cluster samples violate the simple random sample assumption of independence of observations. Failure to account for the intra-cluster correlation of observations when sampling through clusters may lead to an under-powered study. Researchers therefore need estimates of intra-cluster correlation for a range of outcomes to calculate sample size. We report intra-cluster correlation coefficients observed within a large-scale cross-sectional study of general practice in Australia, where the general practitioner (GP) was the primary sampling unit and the patient encounter was the unit of inference. Methods Each year the Bettering the Evaluation and Care of Health (BEACH) study recruits a random sample of approximately 1,000 GPs across Australia. Each GP completes details of 100 consecutive patient encounters. Intra-cluster correlation coefficients were estimated for patient demographics, morbidity managed and treatments received. Intra-cluster correlation coefficients were estimated for descriptive outcomes and for associations between outcomes and predictors and were compared across two independent samples of GPs drawn three years apart. Results Between April 1999 and March 2000, a random sample of 1,047 Australian general practitioners recorded details of 104,700 patient encounters. Intra-cluster correlation coefficients for patient demographics ranged from 0.055 for patient sex to 0.451 for language spoken at home. Intra-cluster correlations for morbidity variables ranged from 0.005 for the management of eye problems to 0.059 for management of psychological problems. Intra-cluster correlation for the association between two variables was smaller than the descriptive intra-cluster correlation of each variable. When compared with the April 2002 to March 2003 sample (1,008 GPs) the estimated intra-cluster correlation coefficients were found to be consistent across samples. Conclusions The demonstrated

  15. Helium cluster isolation spectroscopy

    NASA Astrophysics Data System (ADS)

    Higgins, John Paul

    Clusters of helium, each containing ~103- 104 atoms, are produced in a molecular beam and are doped with alkali metal atoms (Li, Na, and K) and large organic molecules. Electronic spectroscopy in the visible and UV regions of the spectrum is carried out on the dopant species. Since large helium clusters are liquid and attain an equilibrium internal temperature of 0.4 K, they interact weakly with atoms or molecules absorbed on their surface or resident inside the cluster. The spectra that are obtained are characterized by small frequency shifts from the positions of the gas phase transitions, narrow lines, and cold vibrational temperatures. Alkali atoms aggregate on the helium cluster surface to form dimers and trimers. The spectra of singlet alkali dimers exhibit the presence of elementary excitations in the superfluid helium cluster matrix. It is found that preparation of the alkali molecules on the surface of helium clusters leads to the preferential formation of high-spin, van der Waals bound, triplet dimers and quartet trimers. Four bound-bound and two bound-free transitions are observed in the triplet manifold of the alkali dimers. The quartet trimers serve as an ideal system for the study of a simple unimolecular reaction in the cold helium cluster environment. Analysis of the lowest quartet state provides valuable insight into three-body forces in a van der Waals trimer. The wide range of atomic and molecular systems studied in this thesis constitutes a preliminary step in the development of helium cluster isolation spectroscopy, a hybrid technique combining the advantages of high resolution spectroscopy with the synthetic, low temperature environment of matrices.

  16. The anterior hypothalamus in cluster headache.

    PubMed

    Arkink, Enrico B; Schmitz, Nicole; Schoonman, Guus G; van Vliet, Jorine A; Haan, Joost; van Buchem, Mark A; Ferrari, Michel D; Kruit, Mark C

    2017-10-01

    Objective To evaluate the presence, localization, and specificity of structural hypothalamic and whole brain changes in cluster headache and chronic paroxysmal hemicrania (CPH). Methods We compared T1-weighted magnetic resonance images of subjects with cluster headache (episodic n = 24; chronic n = 23; probable n = 14), CPH ( n = 9), migraine (with aura n = 14; without aura n = 19), and no headache ( n = 48). We applied whole brain voxel-based morphometry (VBM) using two complementary methods to analyze structural changes in the hypothalamus: region-of-interest analyses in whole brain VBM, and manual segmentation of the hypothalamus to calculate volumes. We used both conservative VBM thresholds, correcting for multiple comparisons, and less conservative thresholds for exploratory purposes. Results Using region-of-interest VBM analyses mirrored to the headache side, we found enlargement ( p < 0.05, small volume correction) in the anterior hypothalamic gray matter in subjects with chronic cluster headache compared to controls, and in all participants with episodic or chronic cluster headache taken together compared to migraineurs. After manual segmentation, hypothalamic volume (mean±SD) was larger ( p < 0.05) both in subjects with episodic (1.89 ± 0.18 ml) and chronic (1.87 ± 0.21 ml) cluster headache compared to controls (1.72 ± 0.15 ml) and migraineurs (1.68 ± 0.19 ml). Similar but non-significant trends were observed for participants with probable cluster headache (1.82 ± 0.19 ml; p = 0.07) and CPH (1.79 ± 0.20 ml; p = 0.15). Increased hypothalamic volume was primarily explained by bilateral enlargement of the anterior hypothalamus. Exploratory whole brain VBM analyses showed widespread changes in pain-modulating areas in all subjects with headache. Interpretation The anterior hypothalamus is enlarged in episodic and chronic cluster headache and possibly also in probable cluster

  17. Dynamical evolution of stars and gas of young embedded stellar sub-clusters

    NASA Astrophysics Data System (ADS)

    Sills, Alison; Rieder, Steven; Scora, Jennifer; McCloskey, Jessica; Jaffa, Sarah

    2018-06-01

    We present simulations of the dynamical evolution of young embedded star clusters. Our initial conditions are directly derived from X-ray, infrared, and radio observations of local systems, and our models evolve both gas and stars simultaneously. Our regions begin with both clustered and extended distributions of stars, and a gas distribution that can include a filamentary structure in addition to gas surrounding the stellar sub-clusters. We find that the regions become spherical, monolithic, and smooth quite quickly, and that the dynamical evolution is dominated by the gravitational interactions between the stars. In the absence of stellar feedback, the gas moves gently out of the centre of our regions but does not have a significant impact on the motions of the stars at the earliest stages of cluster formation. Our models at later times are consistent with observations of similar regions in the local neighbourhood. We conclude that the evolution of young protostar clusters is relatively insensitive to reasonable choices of initial conditions. Models with more realism, such as an initial population of binary and multiple stars and ongoing star formation, are the next step needed to confirm these findings.

  18. STAR-FORMING GALAXIES IN THE HERCULES CLUSTER: H{alpha} IMAGING OF A2151

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cedres, Bernabe; Iglesias-Paramo, Jorge; VIlchez, Jose Manuel

    2009-09-15

    This paper presents the first results of an H{alpha} imaging survey of galaxies in the central regions of the A2151 cluster. A total of 50 sources were detected in H{alpha}, from which 41 were classified as secure members of the cluster and 2 as likely members based on spectroscopic and photometric redshift considerations. The remaining seven galaxies were classified as background contaminants and thus excluded from our study on the H{alpha} properties of the cluster. The morphologies of the 43 H{alpha} selected galaxies range from grand design spirals and interacting galaxies to blue compacts and tidal dwarfs or isolated extragalacticmore » H II regions, spanning a range of magnitudes of -21 {<=} M{sub B} {<=} -12.5 mag. From these 43 galaxies, 7 have been classified as active galactic nucleus (AGN) candidates. These AGN candidates follow the L(H{alpha}) versus M{sub B} relationship of the normal galaxies, implying that the emission associated with the nuclear engine has a rather secondary impact on the total H{alpha} emission of these galaxies. A comparison with the clusters Coma and A1367 and a sample of field galaxies has shown the presence of cluster galaxies with L(H{alpha}) lower than expected for their M{sub B} , a consequence of the cluster environment. This fact results in differences in the L(H{alpha}) versus EW(H{alpha}) and L(H{alpha}) distributions of the clusters with respect to the field, and in cluster-to-cluster variations of these quantities, which we propose are driven by a global cluster property as the total mass. In addition, the cluster H{alpha} emitting galaxies tend to avoid the central regions of the clusters, again with different intensity depending on the cluster total mass. For the particular case of A2151, we find that most H{alpha} emitting galaxies are located close to the regions with the higher galaxy density, offset from the main X-ray peak. Overall, we conclude that both the global cluster environment and the cluster merging

  19. The Clusters AgeS Experiment (CASE). Variable Stars in the Field of the Globular Cluster NGC 3201

    NASA Astrophysics Data System (ADS)

    Kaluzny, J.; Rozyczka, M.; Thompson, I. B.; Narloch, W.; Mazur, B.; Pych, W.; Schwarzenberg-Czerny, A.

    2016-01-01

    The field of the globular cluster NGC 3201 was monitored between 1998 and 2009 in a search for variable stars. BV light curves were obtained for 152 periodic or likely periodic variables, fifty-seven of which are new detections. Thirty-seven newly detected variables are proper motion members of the cluster. Among them we found seven detached or semi-detached eclipsing binaries, four contact binaries, and eight SX Phe pulsators. Four of the eclipsing binaries are located in the turnoff region, one on the lower main sequence and the remaining two slightly above the subgiant branch. Two contact systems are blue stragglers, and another two reside in the turnoff region. In the blue straggler region a total of 266 objects were found, of which 140 are proper motion (PM) members of NGC 3201, and another nineteen are field stars. Seventy-eight of the remaining objects for which we do not have PM data are located within the half-light radius from the center of the cluster, and most of them are likely genuine blue stragglers. Four variable objects in our field of view were found to coincide with X-ray sources: three chromospherically active stars and a quasar at a redshift z≍0.5.

  20. TECHNIQUES TO ASSESS CROSS-BORDER AIR POLLUTION AND APPLICATION TO A U.S.-MEXICO BORDER REGION

    EPA Science Inventory

    A year-long assessment of cross-border air pollution was conducted in the eastmost section of the US-Mexico border region, known as the Lower Rio Grande Valley, in South Texas. Measurements were conducted on the US side and included fine particle mass (PM2.5) and elemental com...

  1. Cluster Analysis and Gaussian Mixture Estimation of Correlated Time-Series by Means of Multi-dimensional Scaling

    NASA Astrophysics Data System (ADS)

    Ibuki, Takero; Suzuki, Sei; Inoue, Jun-ichi

    We investigate cross-correlations between typical Japanese stocks collected through Yahoo!Japan website ( http://finance.yahoo.co.jp/ ). By making use of multi-dimensional scaling (MDS) for the cross-correlation matrices, we draw two-dimensional scattered plots in which each point corresponds to each stock. To make a clustering for these data plots, we utilize the mixture of Gaussians to fit the data set to several Gaussian densities. By minimizing the so-called Akaike Information Criterion (AIC) with respect to parameters in the mixture, we attempt to specify the best possible mixture of Gaussians. It might be naturally assumed that all the two-dimensional data points of stocks shrink into a single small region when some economic crisis takes place. The justification of this assumption is numerically checked for the empirical Japanese stock data, for instance, those around 11 March 2011.

  2. Generalizing MOND to explain the missing mass in galaxy clusters

    NASA Astrophysics Data System (ADS)

    Hodson, Alistair O.; Zhao, Hongsheng

    2017-02-01

    Context. MOdified Newtonian Dynamics (MOND) is a gravitational framework designed to explain the astronomical observations in the Universe without the inclusion of particle dark matter. MOND, in its current form, cannot explain the missing mass in galaxy clusters without the inclusion of some extra mass, be it in the form of neutrinos or non-luminous baryonic matter. We investigate whether the MOND framework can be generalized to account for the missing mass in galaxy clusters by boosting gravity in high gravitational potential regions. We examine and review Extended MOND (EMOND), which was designed to increase the MOND scale acceleration in high potential regions, thereby boosting the gravity in clusters. Aims: We seek to investigate galaxy cluster mass profiles in the context of MOND with the primary aim at explaining the missing mass problem fully without the need for dark matter. Methods: Using the assumption that the clusters are in hydrostatic equilibrium, we can compute the dynamical mass of each cluster and compare the result to the predicted mass of the EMOND formalism. Results: We find that EMOND has some success in fitting some clusters, but overall has issues when trying to explain the mass deficit fully. We also investigate an empirical relation to solve the cluster problem, which is found by analysing the cluster data and is based on the MOND paradigm. We discuss the limitations in the text.

  3. The nongravitational interactions of dark matter in colliding galaxy clusters.

    PubMed

    Harvey, David; Massey, Richard; Kitching, Thomas; Taylor, Andy; Tittley, Eric

    2015-03-27

    Collisions between galaxy clusters provide a test of the nongravitational forces acting on dark matter. Dark matter's lack of deceleration in the "bullet cluster" collision constrained its self-interaction cross section σ(DM)/m < 1.25 square centimeters per gram (cm(2)/g) [68% confidence limit (CL)] (σ(DM), self-interaction cross section; m, unit mass of dark matter) for long-ranged forces. Using the Chandra and Hubble Space Telescopes, we have now observed 72 collisions, including both major and minor mergers. Combining these measurements statistically, we detect the existence of dark mass at 7.6σ significance. The position of the dark mass has remained closely aligned within 5.8 ± 8.2 kiloparsecs of associated stars, implying a self-interaction cross section σ(DM)/m < 0.47 cm(2)/g (95% CL) and disfavoring some proposed extensions to the standard model. Copyright © 2015, American Association for the Advancement of Science.

  4. Tidal stripping stellar substructures around four metal-poor globular clusters in the galactic bulge

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Chun, Sang-Hyun; Kang, Minhee; Jung, DooSeok

    2015-01-01

    We investigate the spatial density configuration of stars around four metal-poor globular clusters (NGC 6266, NGC 6626, NGC 6642, and NGC 6723) in the Galactic bulge region using wide-field deep J, H, and K imaging data obtained with the Wide Field Camera near-infrared array on the United Kingdom Infrared Telescope. A statistical weighted filtering algorithm for the stars on the color–magnitude diagram is applied in order to sort cluster member candidates from the field star contamination. In two-dimensional isodensity contour maps of the clusters, we find that all four of the globular clusters exhibit strong evidence of tidally stripped stellarmore » features beyond the tidal radius in the form of tidal tails or small density lobes/chunks. The orientations of the extended stellar substructures are likely to be associated with the effect of dynamic interaction with the Galaxy and the cluster's space motion. The observed radial density profiles of the four globular clusters also describe the extended substructures; they depart from theoretical King and Wilson models and have an overdensity feature with a break in the slope of the profile at the outer region of clusters. The observed results could imply that four globular clusters in the Galactic bulge region have experienced strong environmental effects such as tidal forces or bulge/disk shocks of the Galaxy during the dynamical evolution of globular clusters. These observational results provide further details which add to our understanding of the evolution of clusters in the Galactic bulge region as well as the formation of the Galaxy.« less

  5. Star cluster formation history along the minor axis of the Large Magellanic Cloud

    NASA Astrophysics Data System (ADS)

    Piatti, Andrés E.; Cole, Andrew A.; Emptage, Bryn

    2018-01-01

    We analysed Washington CMT1 photometry of star clusters located along the minor axis of the Large Magellanic Cloud (LMC), from the LMC optical centre up to ∼39° outwards to the North-West. The data base was exploited in order to search for new star cluster candidates, to produce cluster CMDs cleaned from field star contamination and to derive age estimates for a statistically complete cluster sample. We confirmed that 146 star cluster candidates are genuine physical systems, and concluded that an overall ∼30 per cent of catalogued clusters in the surveyed regions are unlikely to be true physical systems. We did not find any new cluster candidates in the outskirts of the LMC (deprojected distance ≳ 8°). The derived ages of the studied clusters are in the range 7.2 < log(t yr-1) ≤ 9.4, with the sole exception of the globular cluster NGC 1786 (log(t yr-1) = 10.10). We also calculated the cluster frequency for each region, from which we confirmed previously proposed outside-in formation scenarios. In addition, we found that the outer LMC fields show a sudden episode of cluster formation (log(t yr-1) ∼7.8-7.9) which continued until log(t yr-1) ∼7.3 only in the outermost LMC region. We link these features to the first pericentre passage of the LMC to the Milky Way (MW), which could have triggered cluster formation due to ram pressure interaction between the LMC and MW halo.

  6. Detection of CO emission in Hydra 1 cluster galaxies

    NASA Technical Reports Server (NTRS)

    Huchtmeier, W. K.

    1990-01-01

    A survey of bright Hydra cluster spiral galaxies for the CO(1-0) transition at 115 GHz was performed with the 15m Swedish-ESO submillimeter telescope (SEST). Five out of 15 galaxies observed have been detected in the CO(1-0) line. The largest spiral galaxy in the cluster, NGC 3312, got more CO than any spiral of the Virgo cluster. This Sa-type galaxy is optically largely distorted and disrupted on one side. It is a good candidate for ram pressure stripping while passing through the cluster's central region. A comparison with global CO properties of Virgo cluster spirals shows a relatively good agreement with the detected Hydra cluster galaxies.

  7. The JCMT Gould Belt Survey: Dense Core Clusters in Orion B

    NASA Astrophysics Data System (ADS)

    Kirk, H.; Johnstone, D.; Di Francesco, J.; Lane, J.; Buckle, J.; Berry, D. S.; Broekhoven-Fiene, H.; Currie, M. J.; Fich, M.; Hatchell, J.; Jenness, T.; Mottram, J. C.; Nutter, D.; Pattle, K.; Pineda, J. E.; Quinn, C.; Salji, C.; Tisi, S.; Hogerheijde, M. R.; Ward-Thompson, D.; The JCMT Gould Belt Survey Team

    2016-04-01

    The James Clerk Maxwell Telescope Gould Belt Legacy Survey obtained SCUBA-2 observations of dense cores within three sub-regions of Orion B: LDN 1622, NGC 2023/2024, and NGC 2068/2071, all of which contain clusters of cores. We present an analysis of the clustering properties of these cores, including the two-point correlation function and Cartwright’s Q parameter. We identify individual clusters of dense cores across all three regions using a minimal spanning tree technique, and find that in each cluster, the most massive cores tend to be centrally located. We also apply the independent M-Σ technique and find a strong correlation between core mass and the local surface density of cores. These two lines of evidence jointly suggest that some amount of mass segregation in clusters has happened already at the dense core stage.

  8. The velocity field of clusters of galaxies within 100 megaparsecs. II - Northern clusters

    NASA Technical Reports Server (NTRS)

    Mould, J. R.; Akeson, R. L.; Bothun, G. D.; Han, M.; Huchra, J. P.; Roth, J.; Schommer, R. A.

    1993-01-01

    Distances and peculiar velocities for galaxies in eight clusters and groups have been determined by means of the near-infrared Tully-Fisher relation. With the possible exception of a group halfway between us and the Hercules Cluster, we observe peculiar velocities of the same order as the measuring errors of about 400 km/s. The present sample is drawn from the northern Galactic hemisphere and delineates a quiet region in the Hubble flow. This contrasts with the large-scale flows seen in the Hydra-Centaurus and Perseus-Pisces regions. We compare the observed peculiar velocities with predictions based upon the gravity field inferred from the IRAS redshift survey. The differences between the observed and predicted peculiar motions are generally small, except near dense structures, where the observed motions exceed the predictions by significant amounts. Kinematic models of the velocity field are also compared with the data. We cannot distinguish between parameterized models with a great attractor or models with a bulk flow.

  9. An Information-Theoretic-Cluster Visualization for Self-Organizing Maps.

    PubMed

    Brito da Silva, Leonardo Enzo; Wunsch, Donald C

    2018-06-01

    Improved data visualization will be a significant tool to enhance cluster analysis. In this paper, an information-theoretic-based method for cluster visualization using self-organizing maps (SOMs) is presented. The information-theoretic visualization (IT-vis) has the same structure as the unified distance matrix, but instead of depicting Euclidean distances between adjacent neurons, it displays the similarity between the distributions associated with adjacent neurons. Each SOM neuron has an associated subset of the data set whose cardinality controls the granularity of the IT-vis and with which the first- and second-order statistics are computed and used to estimate their probability density functions. These are used to calculate the similarity measure, based on Renyi's quadratic cross entropy and cross information potential (CIP). The introduced visualizations combine the low computational cost and kernel estimation properties of the representative CIP and the data structure representation of a single-linkage-based grouping algorithm to generate an enhanced SOM-based visualization. The visual quality of the IT-vis is assessed by comparing it with other visualization methods for several real-world and synthetic benchmark data sets. Thus, this paper also contains a significant literature survey. The experiments demonstrate the IT-vis cluster revealing capabilities, in which cluster boundaries are sharply captured. Additionally, the information-theoretic visualizations are used to perform clustering of the SOM. Compared with other methods, IT-vis of large SOMs yielded the best results in this paper, for which the quality of the final partitions was evaluated using external validity indices.

  10. Identification of Urban Leprosy Clusters

    PubMed Central

    Paschoal, José Antonio Armani; Paschoal, Vania Del'Arco; Nardi, Susilene Maria Tonelli; Rosa, Patrícia Sammarco; Ismael, Manuela Gallo y Sanches; Sichieri, Eduvaldo Paulo

    2013-01-01

    Overpopulation of urban areas results from constant migrations that cause disordered urban growth, constituting clusters defined as sets of people or activities concentrated in relatively small physical spaces that often involve precarious conditions. Aim. Using residential grouping, the aim was to identify possible clusters of individuals in São José do Rio Preto, Sao Paulo, Brazil, who have or have had leprosy. Methods. A population-based, descriptive, ecological study using the MapInfo and CrimeStat techniques, geoprocessing, and space-time analysis evaluated the location of 425 people treated for leprosy between 1998 and 2010. Clusters were defined as concentrations of at least 8 people with leprosy; a distance of up to 300 meters between residences was adopted. Additionally, the year of starting treatment and the clinical forms of the disease were analyzed. Results. Ninety-eight (23.1%) of 425 geocoded cases were located within one of ten clusters identified in this study, and 129 cases (30.3%) were in the region of a second-order cluster, an area considered of high risk for the disease. Conclusion. This study identified ten clusters of leprosy cases in the city and identified an area of high risk for the appearance of new cases of the disease. PMID:24288467

  11. The ergot alkaloid gene cluster in Claviceps purpurea: extension of the cluster sequence and intra species evolution.

    PubMed

    Haarmann, Thomas; Machado, Caroline; Lübbe, Yvonne; Correia, Telmo; Schardl, Christopher L; Panaccione, Daniel G; Tudzynski, Paul

    2005-06-01

    The genomic region of Claviceps purpurea strain P1 containing the ergot alkaloid gene cluster [Tudzynski, P., Hölter, K., Correia, T., Arntz, C., Grammel, N., Keller, U., 1999. Evidence for an ergot alkaloid gene cluster in Claviceps purpurea. Mol. Gen. Genet. 261, 133-141] was explored by chromosome walking, and additional genes probably involved in the ergot alkaloid biosynthesis have been identified. The putative cluster sequence (extending over 68.5kb) contains 4 different nonribosomal peptide synthetase (NRPS) genes and several putative oxidases. Northern analysis showed that most of the genes were co-regulated (repressed by high phosphate), and identified probable flanking genes by lack of co-regulation. Comparison of the cluster sequences of strain P1, an ergotamine producer, with that of strain ECC93, an ergocristine producer, showed high conservation of most of the cluster genes, but significant variation in the NRPS modules, strongly suggesting that evolution of these chemical races of C. purpurea is determined by evolution of NRPS module specificity.

  12. Suzaku observations of low surface brightness cluster Abell 1631

    NASA Astrophysics Data System (ADS)

    Babazaki, Yasunori; Mitsuishi, Ikuyuki; Ota, Naomi; Sasaki, Shin; Böhringer, Hans; Chon, Gayoung; Pratt, Gabriel W.; Matsumoto, Hironori

    2018-04-01

    We present analysis results for a nearby galaxy cluster Abell 1631 at z = 0.046 using the X-ray observatory Suzaku. This cluster is categorized as a low X-ray surface brightness cluster. To study the dynamical state of the cluster, we conduct four-pointed Suzaku observations and investigate physical properties of the Mpc-scale hot gas associated with the A 1631 cluster for the first time. Unlike relaxed clusters, the X-ray image shows no strong peak at the center and an irregular morphology. We perform spectral analysis and investigate the radial profiles of the gas temperature, density, and entropy out to approximately 1.5 Mpc in the east, north, west, and south directions by combining with the XMM-Newton data archive. The measured gas density in the central region is relatively low (a few ×10-4 cm-3) at the given temperature (˜2.9 keV) compared with X-ray-selected clusters. The entropy profile and value within the central region (r < 0.1 r200) are found to be flatter and higher (≳400 keV cm2). The observed bolometric luminosity is approximately three times lower than that expected from the luminosity-temperature relation in previous studies of relaxed clusters. These features are also observed in another low surface brightness cluster, Abell 76. The spatial distributions of galaxies and the hot gas appear to be different. The X-ray luminosity is relatively lower than that expected from the velocity dispersion. A post-merger scenario may explain the observed results.

  13. Suzaku observations of low surface brightness cluster Abell 1631

    NASA Astrophysics Data System (ADS)

    Babazaki, Yasunori; Mitsuishi, Ikuyuki; Ota, Naomi; Sasaki, Shin; Böhringer, Hans; Chon, Gayoung; Pratt, Gabriel W.; Matsumoto, Hironori

    2018-06-01

    We present analysis results for a nearby galaxy cluster Abell 1631 at z = 0.046 using the X-ray observatory Suzaku. This cluster is categorized as a low X-ray surface brightness cluster. To study the dynamical state of the cluster, we conduct four-pointed Suzaku observations and investigate physical properties of the Mpc-scale hot gas associated with the A 1631 cluster for the first time. Unlike relaxed clusters, the X-ray image shows no strong peak at the center and an irregular morphology. We perform spectral analysis and investigate the radial profiles of the gas temperature, density, and entropy out to approximately 1.5 Mpc in the east, north, west, and south directions by combining with the XMM-Newton data archive. The measured gas density in the central region is relatively low (a few ×10-4 cm-3) at the given temperature (˜2.9 keV) compared with X-ray-selected clusters. The entropy profile and value within the central region (r < 0.1 r200) are found to be flatter and higher (≳400 keV cm2). The observed bolometric luminosity is approximately three times lower than that expected from the luminosity-temperature relation in previous studies of relaxed clusters. These features are also observed in another low surface brightness cluster, Abell 76. The spatial distributions of galaxies and the hot gas appear to be different. The X-ray luminosity is relatively lower than that expected from the velocity dispersion. A post-merger scenario may explain the observed results.

  14. The Earth Observation Technology Cluster

    NASA Astrophysics Data System (ADS)

    Aplin, P.; Boyd, D. S.; Danson, F. M.; Donoghue, D. N. M.; Ferrier, G.; Galiatsatos, N.; Marsh, A.; Pope, A.; Ramirez, F. A.; Tate, N. J.

    2012-07-01

    The Earth Observation Technology Cluster is a knowledge exchange initiative, promoting development, understanding and communication about innovative technology used in remote sensing of the terrestrial or land surface. This initiative provides an opportunity for presentation of novel developments from, and cross-fertilisation of ideas between, the many and diverse members of the terrestrial remote sensing community. The Earth Observation Technology Cluster involves a range of knowledge exchange activities, including organisation of technical events, delivery of educational materials, publication of scientific findings and development of a coherent terrestrial EO community. The initiative as a whole covers the full range of remote sensing operation, from new platform and sensor development, through image retrieval and analysis, to data applications and environmental modelling. However, certain topical and strategic themes have been selected for detailed investigation: (1) Unpiloted Aerial Vehicles, (2) Terrestrial Laser Scanning, (3) Field-Based Fourier Transform Infra-Red Spectroscopy, (4) Hypertemporal Image Analysis, and (5) Circumpolar and Cryospheric Application. This paper presents general activities and achievements of the Earth Observation Technology Cluster, and reviews state-of-the-art developments in the five specific thematic areas.

  15. Dynamic clustering scheme based on the coordination of management and control in multi-layer and multi-region intelligent optical network

    NASA Astrophysics Data System (ADS)

    Niu, Xiaoliang; Yuan, Fen; Huang, Shanguo; Guo, Bingli; Gu, Wanyi

    2011-12-01

    A Dynamic clustering scheme based on coordination of management and control is proposed to reduce network congestion rate and improve the blocking performance of hierarchical routing in Multi-layer and Multi-region intelligent optical network. Its implement relies on mobile agent (MA) technology, which has the advantages of efficiency, flexibility, functional and scalability. The paper's major contribution is to adjust dynamically domain when the performance of working network isn't in ideal status. And the incorporation of centralized NMS and distributed MA control technology migrate computing process to control plane node which releases the burden of NMS and improves process efficiently. Experiments are conducted on Multi-layer and multi-region Simulation Platform for Optical Network (MSPON) to assess the performance of the scheme.

  16. Object-Oriented Image Clustering Method Using UAS Photogrammetric Imagery

    NASA Astrophysics Data System (ADS)

    Lin, Y.; Larson, A.; Schultz-Fellenz, E. S.; Sussman, A. J.; Swanson, E.; Coppersmith, R.

    2016-12-01

    Unmanned Aerial Systems (UAS) have been used widely as an imaging modality to obtain remotely sensed multi-band surface imagery, and are growing in popularity due to their efficiency, ease of use, and affordability. Los Alamos National Laboratory (LANL) has employed the use of UAS for geologic site characterization and change detection studies at a variety of field sites. The deployed UAS equipped with a standard visible band camera to collect imagery datasets. Based on the imagery collected, we use deep sparse algorithmic processing to detect and discriminate subtle topographic features created or impacted by subsurface activities. In this work, we develop an object-oriented remote sensing imagery clustering method for land cover classification. To improve the clustering and segmentation accuracy, instead of using conventional pixel-based clustering methods, we integrate the spatial information from neighboring regions to create super-pixels to avoid salt-and-pepper noise and subsequent over-segmentation. To further improve robustness of our clustering method, we also incorporate a custom digital elevation model (DEM) dataset generated using a structure-from-motion (SfM) algorithm together with the red, green, and blue (RGB) band data for clustering. In particular, we first employ an agglomerative clustering to create an initial segmentation map, from where every object is treated as a single (new) pixel. Based on the new pixels obtained, we generate new features to implement another level of clustering. We employ our clustering method to the RGB+DEM datasets collected at the field site. Through binary clustering and multi-object clustering tests, we verify that our method can accurately separate vegetation from non-vegetation regions, and are also able to differentiate object features on the surface.

  17. Neck circumference and clustered cardiovascular risk factors in children and adolescents: cross-sectional study.

    PubMed

    Castro-Piñero, José; Delgado-Alfonso, Alvaro; Gracia-Marco, Luis; Gómez-Martínez, Sonia; Esteban-Cornejo, Irene; Veiga, Oscar L; Marcos, Ascensión; Segura-Jiménez, Víctor

    2017-09-11

    Early detection of cardiovascular disease (CVD) risk factors, such as obesity, is crucial to prevent adverse long-term effects on individuals' health. Therefore, the aims were: (1) to explore the robustness of neck circumference (NC) as a predictor of CVD and examine its association with numerous anthropometric and body composition indices and (2) to release sex and age-specific NC cut-off values to classify youths as overweight/obese. Cross-sectional study. 23 primary schools and 17 secondary schools from Spain. 2198 students (1060 girls), grades 1-4 and 7-10. Pubertal development, anthropometric and body composition indices, systolic and diastolic blood pressure (SBP and DBP, respectively), cardiorespiratory fitness, blood sampling triglycerides (TG), total cholesterol (TC), high-density lipoprotein cholesterol (HDL-c), low-density lipoprotein cholesterol (LDL-c), glucose and inflammatory markers. Homoeostasis model assessment (HOMA-IR) and cluster of CVD risk factors were calculated. NC was negatively associated with maximum oxygen consumption (R2=0.231, P<0.001 for boys; R2=0.018, P<0.001 for girls) and adiponectin (R2=0.049, P<0.001 for boys; R2=0.036, P<0.001 for girls); and positively associated with SBP, DBP, TC/HDL-c, TG, HOMA, complement factors C-3 and C-4, leptin and clustered CVD risk factor in both sexes (R2 from 0.035 to 0.353, P<0.01 for boys; R2 from 0.024 to 0.215, P<0.001 for girls). Moreover, NC was positively associated with serum C reactive protein and LDL-c only in boys (R2 from 0.013 to 0.055, P<0.05). NC is a simple, low-cost and practical screening tool of excess of upper body obesity and CVD risk factors in children and adolescents. Paediatricians can easily use it as a screening tool for overweight/obesity in children and adolescents. For this purpose, sex and age-specific thresholds to classify children and adolescents as normal weight or overweight/obese are provided. © Article author(s) (or their employer(s) unless otherwise stated

  18. Cluster analysis of multiple planetary flow regimes

    NASA Technical Reports Server (NTRS)

    Mo, Kingtse; Ghil, Michael

    1988-01-01

    A modified cluster analysis method developed for the classification of quasi-stationary events into a few planetary flow regimes and for the examination of transitions between these regimes is described. The method was applied first to a simple deterministic model and then to a 500-mbar data set for Northern Hemisphere (NH), for which cluster analysis was carried out in the subspace of the first seven empirical orthogonal functions (EOFs). Stationary clusters were found in the low-frequency band of more than 10 days, while transient clusters were found in the band-pass frequency window between 2.5 and 6 days. In the low-frequency band, three pairs of clusters determined EOFs 1, 2, and 3, respectively; they exhibited well-known regional features, such as blocking, the Pacific/North American pattern, and wave trains. Both model and low-pass data exhibited strong bimodality.

  19. [Profile distribution of soil aggregates organic carbon in primary forests in Karst cluster-peak depression region].

    PubMed

    Lu, Ling-Xiao; Song, Tong-Qing; Peng, Wan-Xia; Zeng, Fu-Ping; Wang, Ke-Lin; Xu, Yun-Lei; Yu, Zi; Liu, Yan

    2012-05-01

    Soil profiles were collected from three primary forests (Itoa orientalis, Platycladus orientalis, and Radermachera sinica) in Karst cluster-peak depression region to study the composition of soil aggregates, their organic carbon contents, and the profile distribution of the organic carbon. In the three forests, >2 mm soil aggregates were dominant, occupying about 76% of the total. The content of soil total organic carbon ranged from 12.73 to 68.66 g x kg(-1), with a significant difference among the forests. The organic carbon content in <1 mm soil aggregates was slightly higher than that in >2 mm soil aggregates, but most of soil organic carbon was stored in the soil aggregates with greater particle sizes. About 70% of soil organic carbon came from >2 mm soil aggregates. There was a significant positive relationship between the contents of 2-5 and 5-8 mm soil aggregates and the content of soil organic carbon. To increase the contents of 2-8 mm soil aggregates could effectively improve the soil carbon sequestration in Karst region. In Itoa orientalis forest, 2-8 mm soil aggregates accounted for 46% of the total, and the content of soil total organic carbon reached to 37.62 g x kg(-1), which implied that Itoa orientalis could be the suitable tree species for the ecological restoration in Karst region.

  20. Hubble Watches Star Clusters on a Collision Course

    NASA Image and Video Library

    2012-08-16

    Image release August 16, 2012 Astronomers using data from NASA's Hubble Space Telescope have caught two clusters full of massive stars that may be in the early stages of merging. The 30 Doradus Nebula is 170,000 light-years from Earth. What at first was thought to be only one cluster in the core of the massive star-forming region 30 Doradus has been found to be a composite of two clusters that differ in age by about one million years. The entire 30 Doradus complex has been an active star-forming region for 25 million years, and it is currently unknown how much longer this region can continue creating new stars. Smaller systems that merge into larger ones could help to explain the origin of some of the largest known star clusters. The Hubble observations, made with the Wide Field Camera 3, were taken Oct. 20-27, 2009. The blue color is light from the hottest, most massive stars; the green from the glow of oxygen; and the red from fluorescing hydrogen. To read more about this image go to: www.nasa.gov/mission_pages/hubble/science/cluster-collisi... Image Credit: NASA, ESA, and E. Sabbi (ESA/STScI) NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram

  1. Improved absorption cross-sections of oxygen in the wavelength region 205-240 nm of the Herzberg continuum

    NASA Technical Reports Server (NTRS)

    Yoshino, K.; Cheung, A. S.-C.; Esmond, J. R.; Parkinson, W. H.; Freeman, D. E.

    1988-01-01

    The laboratory values of the Herzberg continuum absorption cross-section of oxygen at room temperature from Cheung et al. (1986) and Jenouvrier et al. (1986) are compared and analyzed. It is found that there is no discrepancy between the absolute values of these two sets of independent measurements. The values are combined in a linear least-squares fit to obtain improved values of the Herzberg continuum cross-section of oxygen at room temperature throughout the wavelength region 205-240 nm. The results are compared with in situ and other laboratory measurements.

  2. Impact of Regulation on Spectral Clustering

    DTIC Science & Technology

    2014-07-22

    the eigenvector values. The regularization parameter was taken to be n. The shaded blue and pink regions corresponds to the nodes belonging to the two...values. As before, the shaded blue and pink regions corresponds to the nodes belonging to the two strong clusters. For plots (a) & (b) the blue line... pink regions corresponds to the nodes belonging to the liberal and conservative blogs respectively. insensitive for large τ . In this case 70% of the

  3. The Next Generation Fornax Survey (NGFS). IV. Mass and Age Bimodality of Nuclear Clusters in the Fornax Core Region

    NASA Astrophysics Data System (ADS)

    Ordenes-Briceño, Yasna; Puzia, Thomas H.; Eigenthaler, Paul; Taylor, Matthew A.; Muñoz, Roberto P.; Zhang, Hongxin; Alamo-Martínez, Karla; Ribbeck, Karen X.; Grebel, Eva K.; Ángel, Simón; Côté, Patrick; Ferrarese, Laura; Hilker, Michael; Lançon, Ariane; Mieske, Steffen; Miller, Bryan W.; Rong, Yu; Sánchez-Janssen, Ruben

    2018-06-01

    We present the analysis of 61 nucleated dwarf galaxies in the central regions (≲R vir/4) of the Fornax galaxy cluster. The galaxies and their nuclei are studied as part of the Next Generation Fornax Survey using optical imaging obtained with the Dark Energy Camera mounted at Blanco/Cerro Tololo Inter-American Observatory and near-infrared data obtained with VIRCam at VISTA/ESO. We decompose the nucleated dwarfs in nucleus and spheroid, after subtracting the surface brightness profile of the spheroid component and studying the nucleus using point source photometry. In general, nuclei are consistent with colors of confirmed metal-poor globular clusters, but with significantly smaller dispersion than other confirmed compact stellar systems in Fornax. We find a bimodal nucleus mass distribution with peaks located at {log}({{ \\mathcal M }}* /{M}ȯ )≃ 5.4 and ∼6.3. These two nucleus subpopulations have different stellar population properties: the more massive nuclei are older than ∼2 Gyr and have metal-poor stellar populations (Z ≤ 0.02 Z ⊙), while the less massive nuclei are younger than ∼2 Gyr with metallicities in the range 0.02 < Z/Z ⊙ ≤ 1. We find that the nucleus mass ({{ \\mathcal M }}nuc}) versus galaxy mass ({{ \\mathcal M }}gal}) relation becomes shallower for less massive galaxies starting around 108 M ⊙, and the mass ratio {η }n={{ \\mathcal M }}nuc}/{{ \\mathcal M }}gal} shows a clear anticorrelation with {{ \\mathcal M }}gal} for the lowest masses, reaching 10%. We test current theoretical models of nuclear cluster formation and find that they cannot fully reproduce the observed trends. A likely mixture of in situ star formation and star cluster mergers seems to be acting during nucleus growth over cosmic time.

  4. Probing Massive Star Cluster Formation with ALMA

    NASA Astrophysics Data System (ADS)

    Johnson, Kelsey

    2015-08-01

    Observationally constraining the physical conditions that give rise to massive star clusters has been a long-standing challenge. Now with the ALMA Observatory coming on-line, we can finally begin to probe the birth environments of massive clusters in a variety of galaxies with sufficient angular resolution. In this talk I will give an overview of ALMA observations of galaxies in which candidate proto-super star cluster molecular clouds have been identified. These new data probe the physical conditions that give rise to super star clusters, providing information on their densities, pressures, and temperatures. In particular, the observations indicate that these clouds may be subject to external pressures of P/k > 108 K cm-3, which is consistent with the prevalence of optically observed adolescent super star clusters in interacting galaxy systems and other high pressure environments. ALMA observations also enable an assessement of the molecular cloud chemical abundances in the regions surrounding super star clusters. Molecular clouds associated with existing super star clusters are strongly correlated with HCO+ emission, but appear to have relatively low ratio of CO/HCO+ emission compared to other clouds, indicating that the super star clusters are impacting the molecular abundances in their vicinity.

  5. Image Patch Analysis of Sunspots and Active Regions

    NASA Astrophysics Data System (ADS)

    Moon, K.; Delouille, V.; Hero, A.

    2017-12-01

    The flare productivity of an active region has been observed to be related to its spatial complexity. Separating active regions that are quiet from potentially eruptive ones is a key issue in space weather applications. Traditional classification schemes such as Mount Wilson and McIntosh have been effective in relating an active region large scale magnetic configuration to its ability to produce eruptive events. However, their qualitative nature does not use all of the information present in the observations. In our work, we present an image patch analysis for characterizing sunspots and active regions. We first propose fine-scale quantitative descriptors for an active region's complexity such as intrinsic dimension, and we relate them to the Mount Wilson classification. Second, we introduce a new clustering of active regions that is based on the local geometry observed in Line of Sight magnetogram and continuum images. To obtain this local geometry, we use a reduced-dimension representation of an active region that is obtained by factoring the corresponding data matrix comprised of local image patches using the singular value decomposition. The resulting factorizations of active regions can be compared via the definition of appropriate metrics on the factors. The distances obtained from these metrics are then used to cluster the active regions. Results. We find that these metrics result in natural clusterings of active regions. The clusterings are related to large scale descriptors of an active region such as its size, its local magnetic field distribution, and its complexity as measured by the Mount Wilson classification scheme. We also find that including data focused on the neutral line of an active region can result in an increased correspondence between our clustering results and other active region descriptors such as the Mount Wilson classifications and the R-value.

  6. K-means cluster analysis of tourist destination in special region of Yogyakarta using spatial approach and social network analysis (a case study: post of @explorejogja instagram account in 2016)

    NASA Astrophysics Data System (ADS)

    Iswandhani, N.; Muhajir, M.

    2018-03-01

    This research was conducted in Department of Statistics Islamic University of Indonesia. The data used are primary data obtained by post @explorejogja instagram account from January until December 2016. In the @explorejogja instagram account found many tourist destinations that can be visited by tourists both in the country and abroad, Therefore it is necessary to form a cluster of existing tourist destinations based on the number of likes from user instagram assumed as the most popular. The purpose of this research is to know the most popular distribution of tourist spot, the cluster formation of tourist destinations, and central popularity of tourist destinations based on @explorejogja instagram account in 2016. Statistical analysis used is descriptive statistics, k-means clustering, and social network analysis. The results of this research were obtained the top 10 most popular destinations in Yogyakarta, map of html-based tourist destination distribution consisting of 121 tourist destination points, formed 3 clusters each consisting of cluster 1 with 52 destinations, cluster 2 with 9 destinations and cluster 3 with 60 destinations, and Central popularity of tourist destinations in the special region of Yogyakarta by district.

  7. Arc4nix: A cross-platform geospatial analytical library for cluster and cloud computing

    NASA Astrophysics Data System (ADS)

    Tang, Jingyin; Matyas, Corene J.

    2018-02-01

    Big Data in geospatial technology is a grand challenge for processing capacity. The ability to use a GIS for geospatial analysis on Cloud Computing and High Performance Computing (HPC) clusters has emerged as a new approach to provide feasible solutions. However, users lack the ability to migrate existing research tools to a Cloud Computing or HPC-based environment because of the incompatibility of the market-dominating ArcGIS software stack and Linux operating system. This manuscript details a cross-platform geospatial library "arc4nix" to bridge this gap. Arc4nix provides an application programming interface compatible with ArcGIS and its Python library "arcpy". Arc4nix uses a decoupled client-server architecture that permits geospatial analytical functions to run on the remote server and other functions to run on the native Python environment. It uses functional programming and meta-programming language to dynamically construct Python codes containing actual geospatial calculations, send them to a server and retrieve results. Arc4nix allows users to employ their arcpy-based script in a Cloud Computing and HPC environment with minimal or no modification. It also supports parallelizing tasks using multiple CPU cores and nodes for large-scale analyses. A case study of geospatial processing of a numerical weather model's output shows that arcpy scales linearly in a distributed environment. Arc4nix is open-source software.

  8. THE JCMT GOULD BELT SURVEY: DENSE CORE CLUSTERS IN ORION A

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lane, J.; Kirk, H.; Johnstone, D.

    The Orion A molecular cloud is one of the most well-studied nearby star-forming regions, and includes regions of both highly clustered and more dispersed star formation across its full extent. Here, we analyze dense, star-forming cores identified in the 850 and 450 μ m SCUBA-2 maps from the JCMT Gould Belt Legacy Survey. We identify dense cores in a uniform manner across the Orion A cloud and analyze their clustering properties. Using two independent lines of analysis, we find evidence that clusters of dense cores tend to be mass segregated, suggesting that stellar clusters may have some amount of primordial mass segregationmore » already imprinted in them at an early stage. We also demonstrate that the dense core clusters have a tendency to be elongated, perhaps indicating a formation mechanism linked to the filamentary structure within molecular clouds.« less

  9. Structures in the Great Attractor region

    NASA Astrophysics Data System (ADS)

    Radburn-Smith, D. J.; Lucey, J. R.; Woudt, P. A.; Kraan-Korteweg, R. C.; Watson, F. G.

    2006-07-01

    To further our understanding of the Great Attractor (GA), we have undertaken a redshift survey using the 2-degree Field (2dF) instrument on the Anglo-Australian Telescope (AAT). Clusters and filaments in the GA region were targeted with 25 separate pointings resulting in approximately 2600 new redshifts. Targets included poorly studied X-ray clusters from the Clusters in the Zone of Avoidance (CIZA) Catalogue as well as the Cen-Crux and PKS 1343-601 clusters, both of which lie close to the classic GA centre. For nine clusters in the region, we report velocity distributions as well as virial and projected mass estimates. The virial mass of CIZA J1324.7-5736, now identified as a separate structure from the Cen-Crux cluster, is found to be ˜3 × 1014-M⊙, in good agreement with the X-ray inferred mass. In the PKS 1343-601 field, five redshifts are measured of which four are new. An analysis of redshifts from this survey, in combination with those from the literature, reveals the dominant structure in the GA region to be a large filament, which appears to extend from Abell S0639 (l= 281°, b=+11°) to (l˜ 5°, b˜-50°), encompassing the Cen-Crux, CIZA J1324.7-5736, Norma and Pavo II clusters. Behind the Norma cluster at cz˜ 15-000-km-s-1, the masses of four rich clusters are calculated. These clusters (Triangulum Australis, Ara, CIZA J1514.6-4558 and CIZA J1410.4-4246) may contribute to a continued large-scale flow beyond the GA. The results of these observations will be incorporated into a subsequent analysis of the GA flow.

  10. LoCuSS: The infall of X-ray groups onto massive clusters

    NASA Astrophysics Data System (ADS)

    Haines, C. P.; Finoguenov, A.; Smith, G. P.; Babul, A.; Egami, E.; Mazzotta, P.; Okabe, N.; Pereira, M. J.; Bianconi, M.; McGee, S. L.; Ziparo, F.; Campusano, L. E.; Loyola, C.

    2018-03-01

    Galaxy clusters are expected to form hierarchically in a ΛCDM universe, growing primarily through mergers with lower mass clusters and the continual accretion of group-mass halos. Galaxy clusters assemble late, doubling their masses since z ˜ 0.5, and so the outer regions of clusters should be replete with accreting group-mass systems. We present an XMM-Newton survey to search for X-ray groups in the infall regions of 23 massive galaxy clusters ( ˜ 1015 M⊙) at z ˜ 0.2, identifying 39 X-ray groups that have been spectroscopically confirmed to lie at the cluster redshift. These groups have mass estimates in the range 2 × 1013 - 7 × 1014 M⊙, and group-to-cluster mass ratios as low as 0.02. The comoving number density of X-ray groups in the infall regions is ˜25 × higher than that seen for isolated X-ray groups from the XXL survey. The average mass per cluster contained within these X-ray groups is 2.2 × 1014 M⊙, or 19 ± 5% of the mass within the primary cluster itself. We estimate that ˜1015 M⊙ clusters increase their masses by 16 ± 4% between z = 0.223 and the present day due to the accretion of groups with M200 ≥ 1013.2 M⊙. This represents about half of the expected mass growth rate of clusters at these late epochs. The other half is likely to come from smooth accretion of matter not bound within halos. The mass function of the infalling X-ray groups appears significantly top heavy with respect to that of "field" X-ray systems, consistent with expectations from numerical simulations, and the basic consequences of collapsed massive dark matter halos being biased tracers of the underlying large-scale density distribution.

  11. GLOBULAR CLUSTERS AND SPUR CLUSTERS IN NGC 4921, THE BRIGHTEST SPIRAL GALAXY IN THE COMA CLUSTER

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lee, Myung Gyoon; Jang, In Sung, E-mail: mglee@astro.snu.ac.kr, E-mail: isjang@astro.snu.ac.kr

    2016-03-01

    We resolve a significant fraction of globular clusters (GCs) in NGC 4921, the brightest spiral galaxy in the Coma cluster. We also find a number of extended bright star clusters (star complexes) in the spur region of the arms. The latter are much brighter and bluer than those in the normal star-forming region, being as massive as 3 × 10{sup 5} M{sub ⊙}. The color distribution of the GCs in this galaxy is found to be bimodal. The turnover magnitudes of the luminosity functions of the blue (metal-poor) GCs (0.70 < (V − I) ≤ 1.05) in the halo are estimated V(max) = 27.11 ± 0.09 mag and I(max) = 26.21 ± 0.11 mag.more » We obtain similar values for NGC 4923, a companion S0 galaxy, and two Coma cD galaxies (NGC 4874 and NGC 4889). The mean value for the turnover magnitudes of these four galaxies is I(max) = 26.25 ± 0.03 mag. Adopting M{sub I} (max) = −8.56 ± 0.09 mag for the metal-poor GCs, we determine the mean distance to the four Coma galaxies to be 91 ± 4 Mpc. Combining this with the Coma radial velocity, we derive a value of the Hubble constant, H{sub 0} = 77.9 ± 3.6 km s{sup −1} Mpc{sup −1}. We estimate the GC specific frequency of NGC 4921 to be S{sub N} = 1.29 ± 0.25, close to the values for early-type galaxies. This indicates that NGC 4921 is in the transition phase to S0s.« less

  12. Low-temperature transonic cooling flows in galaxy clusters

    NASA Technical Reports Server (NTRS)

    Sulkanen, Martin E.; Burns, Jack O.; Norman, Michael L.

    1989-01-01

    Calculations are presented which demonstrate that cooling flow models with large sonic radii may be consistent with observed cluster gas properties. It is found that plausible cluster parameters and cooling flow mass accretion rates can produce sonic radii of 10-20 kpc for sonic point temperatures of 1-3 x 10 to the 6th K. The numerical calculations match these cooling flows to hydrostatic atmosphere solutions for the cluster gas beyond the cooling flow region. The cooling flows produce no appreciable 'holes' in the surface brightness toward the cluster center, and the model can be made to match the observed X-ray surface brightness of three clusters in which cooling flows had been believed to be absent. It is suggested that clusters with low velocity dispersion may be the natural location for such 'cool' cooling flows, and fits of these models to the X-ray surface brightness profiles for three clusters are presented.

  13. DISCOVERY OF A DISSOCIATIVE GALAXY CLUSTER MERGER WITH LARGE PHYSICAL SEPARATION

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Dawson, William A.; Wittman, David; Jee, M. James

    2012-03-10

    We present DLSCL J0916.2+2951 (z = 0.53), a newly discovered major cluster merger in which the collisional cluster gas has become dissociated from the collisionless galaxies and dark matter (DM). We identified the cluster using optical and weak-lensing observations as part of the Deep Lens Survey. Our follow-up observations with Keck, Subaru, Hubble Space Telescope, and Chandra show that the cluster is a dissociative merger and constrain the DM self-interaction cross-section {sigma}{sub DM} m{sup -1}{sub DM} {approx}< 7 cm{sup 2} g{sup -1}. The system is observed at least 0.7 {+-} 0.2 Gyr since first pass-through, thus providing a picture ofmore » cluster mergers 2-5 times further progressed than similar systems observed to date. This improved temporal leverage has implications for our understanding of merging clusters and their impact on galaxy evolution.« less

  14. Superresolution Imaging of Aquaporin-4 Cluster Size in Antibody-Stained Paraffin Brain Sections

    PubMed Central

    Smith, Alex J.; Verkman, Alan S.

    2015-01-01

    The water channel aquaporin-4 (AQP4) forms supramolecular clusters whose size is determined by the ratio of M1- and M23-AQP4 isoforms. In cultured astrocytes, differences in the subcellular localization and macromolecular interactions of small and large AQP4 clusters results in distinct physiological roles for M1- and M23-AQP4. Here, we developed quantitative superresolution optical imaging methodology to measure AQP4 cluster size in antibody-stained paraffin sections of mouse cerebral cortex and spinal cord, human postmortem brain, and glioma biopsy specimens. This methodology was used to demonstrate that large AQP4 clusters are formed in AQP4−/− astrocytes transfected with only M23-AQP4, but not in those expressing only M1-AQP4, both in vitro and in vivo. Native AQP4 in mouse cortex, where both isoforms are expressed, was enriched in astrocyte foot-processes adjacent to microcapillaries; clusters in perivascular regions of the cortex were larger than in parenchymal regions, demonstrating size-dependent subcellular segregation of AQP4 clusters. Two-color superresolution imaging demonstrated colocalization of Kir4.1 with AQP4 clusters in perivascular areas but not in parenchyma. Surprisingly, the subcellular distribution of AQP4 clusters was different between gray and white matter astrocytes in spinal cord, demonstrating regional specificity in cluster polarization. Changes in AQP4 subcellular distribution are associated with several neurological diseases and we demonstrate that AQP4 clustering was preserved in a postmortem human cortical brain tissue specimen, but that AQP4 was not substantially clustered in a human glioblastoma specimen despite high-level expression. Our results demonstrate the utility of superresolution optical imaging for measuring the size of AQP4 supramolecular clusters in paraffin sections of brain tissue and support AQP4 cluster size as a primary determinant of its subcellular distribution. PMID:26682810

  15. MAPS OF MASSIVE CLUMPS IN THE EARLY STAGE OF CLUSTER FORMATION: TWO MODES OF CLUSTER FORMATION, COEVAL OR NON-COEVAL?

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Higuchi, Aya E.; Saito, Masao; Mauersberger, Rainer

    2013-03-10

    We present maps of seven young massive molecular clumps within five target regions in C{sup 18}O (J = 1-0) line emission, using the Nobeyama 45 m telescope. These clumps, which are not associated with clusters, lie at distances between 0.7 and 2.1 kpc. We find C{sup 18}O clumps with radii of 0.5-1.7 pc, masses of 470-4200 M{sub Sun }, and velocity widths of 1.4-3.3 km s{sup -1}. All of the clumps are massive and approximately in virial equilibrium, suggesting they will potentially form clusters. Three of our target regions are associated with H II regions (CWHRs), while the other twomore » are unassociated with H II regions (CWOHRs). The C{sup 18}O clumps can be classified into two morphological types: CWHRs with a filamentary or shell-like structure and spherical CWOHRs. The two CWOHRs have systematic velocity gradients. Using the publicly released WISE database, Class I and Class II protostellar candidates are identified within the C{sup 18}O clumps. The fraction of Class I candidates among all YSO candidates (Class I+Class II) is {>=}50% in CWHRs and {<=}50% in CWOHRs. We conclude that effects from the H II regions can be seen in (1) the spatial distributions of the clumps: filamentary or shell-like structure running along the H II regions; (2) the velocity structures of the clumps: large velocity dispersion along shells; and (3) the small age spreads of YSOs. The small spreads in age of the YSOs show that the presence of H II regions tends to trigger coeval cluster formation.« less

  16. Computer aided detection of clusters of microcalcifications on full field digital mammograms

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ge Jun; Sahiner, Berkman; Hadjiiski, Lubomir M.

    2006-08-15

    We are developing a computer-aided detection (CAD) system to identify microcalcification clusters (MCCs) automatically on full field digital mammograms (FFDMs). The CAD system includes six stages: preprocessing; image enhancement; segmentation of microcalcification candidates; false positive (FP) reduction for individual microcalcifications; regional clustering; and FP reduction for clustered microcalcifications. At the stage of FP reduction for individual microcalcifications, a truncated sum-of-squares error function was used to improve the efficiency and robustness of the training of an artificial neural network in our CAD system for FFDMs. At the stage of FP reduction for clustered microcalcifications, morphological features and features derived from themore » artificial neural network outputs were extracted from each cluster. Stepwise linear discriminant analysis (LDA) was used to select the features. An LDA classifier was then used to differentiate clustered microcalcifications from FPs. A data set of 96 cases with 192 images was collected at the University of Michigan. This data set contained 96 MCCs, of which 28 clusters were proven by biopsy to be malignant and 68 were proven to be benign. The data set was separated into two independent data sets for training and testing of the CAD system in a cross-validation scheme. When one data set was used to train and validate the convolution neural network (CNN) in our CAD system, the other data set was used to evaluate the detection performance. With the use of a truncated error metric, the training of CNN could be accelerated and the classification performance was improved. The CNN in combination with an LDA classifier could substantially reduce FPs with a small tradeoff in sensitivity. By using the free-response receiver operating characteristic methodology, it was found that our CAD system can achieve a cluster-based sensitivity of 70, 80, and 90 % at 0.21, 0.61, and 1.49 FPs/image, respectively. For case

  17. Association schemes perspective of microbubble cluster in ultrasonic fields.

    PubMed

    Behnia, S; Yahyavi, M; Habibpourbisafar, R

    2018-06-01

    Dynamics of a cluster of chaotic oscillators on a network are studied using coupled maps. By introducing the association schemes, we obtain coupling strength in the adjacency matrices form, which satisfies Markov matrices property. We remark that in general, the stability region of the cluster of oscillators at the synchronization state is characterized by Lyapunov exponent which can be defined based on the N-coupled map. As a detailed physical example, dynamics of microbubble cluster in an ultrasonic field are studied using coupled maps. Microbubble cluster dynamics have an indicative highly active nonlinear phenomenon, were not easy to be explained. In this paper, a cluster of microbubbles with a thin elastic shell based on the modified Keller-Herring equation in an ultrasonic field is demonstrated in the framework of the globally coupled map. On the other hand, a relation between the microbubble elements is replaced by a relation between the vertices. Based on this method, the stability region of microbubbles pulsations at complete synchronization state has been obtained analytically. In this way, distances between microbubbles as coupling strength play the crucial role. In the stability region, we thus observe that the problem of study of dynamics of N-microbubble oscillators reduce to that of a single microbubble. Therefore, the important parameters of the isolated microbubble such as applied pressure, driving frequency and the initial radius have effective behavior on the synchronization state. Copyright © 2018 Elsevier B.V. All rights reserved.

  18. NGC 346: Looking in the Cradle of a Massive Star Cluster

    NASA Astrophysics Data System (ADS)

    Gouliermis, Dimitrios A.; Hony, Sacha

    2017-03-01

    How does a star cluster of more than few 10,000 solar masses form? We present the case of the cluster NGC 346 in the Small Magellanic Cloud, still embedded in its natal star-forming region N66, and we propose a scenario for its formation, based on observations of the rich stellar populations in the region. Young massive clusters host a high fraction of early-type stars, indicating an extremely high star formation efficiency. The Milky Way galaxy hosts several young massive clusters that fill the gap between young low-mass open clusters and old massive globular clusters. Only a handful, though, are young enough to study their formation. Moreover, the investigation of their gaseous natal environments suffers from contamination by the Galactic disk. Young massive clusters are very abundant in distant starburst and interacting galaxies, but the distance of their hosting galaxies do not also allow a detailed analysis of their formation. The Magellanic Clouds, on the other hand, host young massive clusters in a wide range of ages with the youngest being still embedded in their giant HII regions. Hubble Space Telescope imaging of such star-forming complexes provide a stellar sampling with a high dynamic range in stellar masses, allowing the detailed study of star formation at scales typical for molecular clouds. Our cluster analysis on the distribution of newly-born stars in N66 shows that star formation in the region proceeds in a clumpy hierarchical fashion, leading to the formation of both a dominant young massive cluster, hosting about half of the observed pre-main-sequence population, and a self-similar dispersed distribution of the remaining stars. We investigate the correlation between stellar surface density (and star formation rate derived from star-counts) and molecular gas surface density (derived from dust column density) in order to unravel the physical conditions that gave birth to NGC 346. A power law fit to the data yields a steep correlation between these

  19. Environment-based selection effects of Planck clusters

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kosyra, R.; Gruen, D.; Seitz, S.

    2015-07-24

    We investigate whether the large-scale structure environment of galaxy clusters imprints a selection bias on Sunyaev–Zel'dovich (SZ) catalogues. Such a selection effect might be caused by line of sight (LoS) structures that add to the SZ signal or contain point sources that disturb the signal extraction in the SZ survey. We use the Planck PSZ1 union catalogue in the Sloan Digital Sky Survey (SDSS) region as our sample of SZ-selected clusters. We calculate the angular two-point correlation function (2pcf) for physically correlated, foreground and background structure in the RedMaPPer SDSS DR8 catalogue with respect to each cluster. We compare ourmore » results with an optically selected comparison cluster sample and with theoretical predictions. In contrast to the hypothesis of no environment-based selection, we find a mean 2pcf for background structures of -0.049 on scales of ≲40 arcmin, significantly non-zero at ~4σ, which means that Planck clusters are more likely to be detected in regions of low background density. We hypothesize this effect arises either from background estimation in the SZ survey or from radio sources in the background. We estimate the defect in SZ signal caused by this effect to be negligibly small, of the order of ~10 -4 of the signal of a typical Planck detection. Analogously, there are no implications on X-ray mass measurements. However, the environmental dependence has important consequences for weak lensing follow up of Planck galaxy clusters: we predict that projection effects account for half of the mass contained within a 15 arcmin radius of Planck galaxy clusters. We did not detect a background underdensity of CMASS LRGs, which also leaves a spatially varying redshift dependence of the Planck SZ selection function as a possible cause for our findings.« less

  20. Local Higher-Order Graph Clustering

    PubMed Central

    Yin, Hao; Benson, Austin R.; Leskovec, Jure; Gleich, David F.

    2018-01-01

    Local graph clustering methods aim to find a cluster of nodes by exploring a small region of the graph. These methods are attractive because they enable targeted clustering around a given seed node and are faster than traditional global graph clustering methods because their runtime does not depend on the size of the input graph. However, current local graph partitioning methods are not designed to account for the higher-order structures crucial to the network, nor can they effectively handle directed networks. Here we introduce a new class of local graph clustering methods that address these issues by incorporating higher-order network information captured by small subgraphs, also called network motifs. We develop the Motif-based Approximate Personalized PageRank (MAPPR) algorithm that finds clusters containing a seed node with minimal motif conductance, a generalization of the conductance metric for network motifs. We generalize existing theory to prove the fast running time (independent of the size of the graph) and obtain theoretical guarantees on the cluster quality (in terms of motif conductance). We also develop a theory of node neighborhoods for finding sets that have small motif conductance, and apply these results to the case of finding good seed nodes to use as input to the MAPPR algorithm. Experimental validation on community detection tasks in both synthetic and real-world networks, shows that our new framework MAPPR outperforms the current edge-based personalized PageRank methodology. PMID:29770258

  1. the-wizz: clustering redshift estimation for everyone

    NASA Astrophysics Data System (ADS)

    Morrison, C. B.; Hildebrandt, H.; Schmidt, S. J.; Baldry, I. K.; Bilicki, M.; Choi, A.; Erben, T.; Schneider, P.

    2017-05-01

    We present the-wizz, an open source and user-friendly software for estimating the redshift distributions of photometric galaxies with unknown redshifts by spatially cross-correlating them against a reference sample with known redshifts. The main benefit of the-wizz is in separating the angular pair finding and correlation estimation from the computation of the output clustering redshifts allowing anyone to create a clustering redshift for their sample without the intervention of an 'expert'. It allows the end user of a given survey to select any subsample of photometric galaxies with unknown redshifts, match this sample's catalogue indices into a value-added data file and produce a clustering redshift estimation for this sample in a fraction of the time it would take to run all the angular correlations needed to produce a clustering redshift. We show results with this software using photometric data from the Kilo-Degree Survey (KiDS) and spectroscopic redshifts from the Galaxy and Mass Assembly survey and the Sloan Digital Sky Survey. The results we present for KiDS are consistent with the redshift distributions used in a recent cosmic shear analysis from the survey. We also present results using a hybrid machine learning-clustering redshift analysis that enables the estimation of clustering redshifts for individual galaxies. the-wizz can be downloaded at http://github.com/morriscb/The-wiZZ/.

  2. An improved K-means clustering method for cDNA microarray image segmentation.

    PubMed

    Wang, T N; Li, T J; Shao, G F; Wu, S X

    2015-07-14

    Microarray technology is a powerful tool for human genetic research and other biomedical applications. Numerous improvements to the standard K-means algorithm have been carried out to complete the image segmentation step. However, most of the previous studies classify the image into two clusters. In this paper, we propose a novel K-means algorithm, which first classifies the image into three clusters, and then one of the three clusters is divided as the background region and the other two clusters, as the foreground region. The proposed method was evaluated on six different data sets. The analyses of accuracy, efficiency, expression values, special gene spots, and noise images demonstrate the effectiveness of our method in improving the segmentation quality.

  3. Reproducibility of Cognitive Profiles in Psychosis Using Cluster Analysis.

    PubMed

    Lewandowski, Kathryn E; Baker, Justin T; McCarthy, Julie M; Norris, Lesley A; Öngür, Dost

    2018-04-01

    Cognitive dysfunction is a core symptom dimension that cuts across the psychoses. Recent findings support classification of patients along the cognitive dimension using cluster analysis; however, data-derived groupings may be highly determined by sampling characteristics and the measures used to derive the clusters, and so their interpretability must be established. We examined cognitive clusters in a cross-diagnostic sample of patients with psychosis and associations with clinical and functional outcomes. We then compared our findings to a previous report of cognitive clusters in a separate sample using a different cognitive battery. Participants with affective or non-affective psychosis (n=120) and healthy controls (n=31) were administered the MATRICS Consensus Cognitive Battery, and clinical and community functioning assessments. Cluster analyses were performed on cognitive variables, and clusters were compared on demographic, cognitive, and clinical measures. Results were compared to findings from our previous report. A four-cluster solution provided a good fit to the data; profiles included a neuropsychologically normal cluster, a globally impaired cluster, and two clusters of mixed profiles. Cognitive burden was associated with symptom severity and poorer community functioning. The patterns of cognitive performance by cluster were highly consistent with our previous findings. We found evidence of four cognitive subgroups of patients with psychosis, with cognitive profiles that map closely to those produced in our previous work. Clusters were associated with clinical and community variables and a measure of premorbid functioning, suggesting that they reflect meaningful groupings: replicable, and related to clinical presentation and functional outcomes. (JINS, 2018, 24, 382-390).

  4. Cardiovascular Risk Factors in Cluster Headache.

    PubMed

    Lasaosa, S Santos; Diago, E Bellosta; Calzada, J Navarro; Benito, A Velázquez

    2017-06-01

     Patients with cluster headache tend to have a dysregulation of systemic blood pressure such as increased blood pressure variability and decreased nocturnal dipping. This pattern of nocturnal nondipping is associated with end-organ damage and increased risk of cardiovascular disease.  To determine if cluster headache is associated with a higher risk of cardiovascular disease.  Cross-sectional study of 33 cluster headache patients without evidence of cardiovascular disease and 30 age- and gender-matched healthy controls. Ambulatory blood pressure monitoring was performed in all subjects. We evaluate anthropometric, hematologic, and structural parameters (carotid intima-media thickness and ankle-brachial index).  Of the 33 cluster headache patients, 16 (48.5%) were nondippers, a higher percentage than expected. Most of the cluster headache patients (69.7%) also presented a pathological ankle-brachial index. In terms of the carotid intima-media thickness values, 58.3% of the patients were in the 75th percentile, 25% were in the 90th percentile, and 20% were in the 95th percentile. In the control group, only five of the 30 subjects (16.7%) had a nondipper pattern ( P  =   0.004), with 4.54% in the 90th and 95th percentiles ( P  =   0.012 and 0.015).  Compared with healthy controls, patients with cluster headache presented a high incidence (48.5%) of nondipper pattern, pathological ankle-brachial index (69.7%), and intima-media thickness values above the 75th percentile. These findings support the hypothesis that patients with cluster headache present increased risk of cardiovascular disease. © 2016 American Academy of Pain Medicine. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com

  5. The Star Cluster System in the Local Group Starburst Galaxy IC 10

    NASA Astrophysics Data System (ADS)

    Lim, Sungsoon; Lee, Myung Gyoon

    2015-05-01

    We present a survey of star clusters in the halo of IC 10, a starburst galaxy in the Local Group, based on Subaru R-band images and NOAO Local Group Survey UBVRI images. We find five new star clusters. All of these star clusters are located far from the center of IC 10, while previously known star clusters are mostly located in the main body. Interestingly, the distribution of these star clusters shows an asymmetrical structure elongated along the east and southwest directions. We derive UBVRI photometry of 66 star clusters, including these new star clusters, as well as previously known star clusters. Ages of the star clusters are estimated from a comparison of their UBVRI spectral energy distribution with the simple stellar population models. We find that the star clusters in the halo are all older than 1 Gyr, while those in the main body have various ages, from very young (several Myr) to old (\\gt 1 Gyr). The young clusters (\\lt 10 Myr) are mostly located in the Hα emission regions and are concentrated on a small region at 2\\prime\\prime in the southeast direction from the galaxy center, while the old clusters are distributed in a wider area than the disk. Intermediate-age clusters (∼100 Myr) are found in two groups. One is close to the location of the young clusters and the other is at ∼ 4\\prime\\prime from the location of the young clusters. The latter may be related to past mergers or tidal interaction.

  6. Time dependent density functional calculation of plasmon response in clusters

    NASA Astrophysics Data System (ADS)

    Wang, Feng; Zhang, Feng-Shou; Eric, Suraud

    2003-02-01

    We have introduced a theoretical scheme for the efficient description of the optical response of a cluster based on the time-dependent density functional theory. The practical implementation is done by means of the fully fledged time-dependent local density approximation scheme, which is solved directly in the time domain without any linearization. As an example we consider the simple Na2 cluster and compute its surface plasmon photoabsorption cross section, which is in good agreement with the experiments.

  7. Plasmasphere-Ring Current-Radiation Belts Interactions: Review of 16 Years of Cluster Observations

    NASA Astrophysics Data System (ADS)

    Dandouras, I. S.

    2016-12-01

    The Cluster mission is based on four identical spacecraft launched in 2000 on similar elliptical polar orbits with an initial perigee at about 4 RE and an apogee at 19.6 RE. This allows Cluster to cross the outer plasmasphere, the ring current region and the radiation belts, from south to north, during every perigee pass and to obtain their latitudinal profile following almost the same flux tube. Due to various perturbations the perigee geocentric distance decreased during 2007-2010 to about 2 RE, whereas actually it is again up to about 5 RE, allowing in this way to study, during the mission, the inner magnetosphere populations and their interactions at a wide range of L-shells and under different solar activity conditions. The CIS experiment, on board these spacecraft, provides the ion distribution functions from 1 eV (plasmasphere populations) up to 40 keV (ring current), whereas the MeV penetrating particles allow to monitor the position and dynamics of the radiation belts. The FGM experiment on board these four spacecraft allowed for the first time an instantaneous calculation of the magnetic field gradients and thus a direct measurement of the local current density using the curlometer technique. Earlier and more recent results, based on Cluster data acquired during the passes in inner magnetosphere, will be reviewed and analysed.

  8. Monitoring Wetland Hydro-dynamics in the Prairie Pothole Region Using Landsat Time Series

    NASA Astrophysics Data System (ADS)

    Zhou, Q.; Rover, J.; Gallant, A.

    2017-12-01

    Wetlands provide a variety of ecosystem functions, while it is spatially and temporally dynamic. We mapped the dynamics of wetlands in the North Dakota Prairie Pothole Region using all available clear observations of Landsat sensor data from 1985 to 2014. We used a cluster analysis to group pixels exhibiting similar long-term spectral trends over seven Landsat bands, then applied the tasseled-cap transformation to evaluate the temporal characteristics of brightness, greenness, and wetness for each cluster. We tested relations between these three indices and hydrologic conditions, as represented by the Palmer Hydrological Drought Index (PHDI), using the cross-correlation analysis for each cluster performed over an eight-year moving window for the 30 years covered by the study. This temporal window size coincided with the timing of a major shift from a prolonged drought that occurred within the first eight years of the study period to wetter conditions that prevailed throughout the remaining years. The 20 cluster we produced represented a gradient from locations that continuously held water throughout the study period to locations that, at most, held water only for short periods in some years. The spatial distribution of the cluster groups reflected patterns of regional geologic and geomorphologic features. Comparisons of the PHDI to tasseled-cap wetness were the most straightforward to interpret among the results from the three indices. Wetness for most cluster groups had high positive correlations with PHDI during drought years, with the correlations reduced as the landscape entered a lengthy, wetter period; however, wetness generally remained highly and positively correlated with PHDI across all years for four cluster groups where the area exhibited two or more multi-year dry-wet cycles. These same four groups also had strong, generally negative correlations with tasseled-cap brightness. For other cluster groups, brightness often was strongly negatively correlated

  9. Helicobacter pylori with the Intact dupA Cluster is more Virulent than the Strains with the Incomplete dupA Cluster.

    PubMed

    Wang, Ming-yi; Shao, Chen; Li, Jie; Yang, Ya-Chao; Wang, Shao-bo; Hao, Jun-ling; Wu, Chun-mei; Gao, Xiao-zhong; Shao, Shi-he

    2015-07-01

    The duodenal ulcer promoting gene (dupA), located in the plasticity region of Helicobacter pylori (H. pylori), is predicted to form a type IV secretory system (T4SS) with vir genes around dupA. In the study, we investigated the association between the dupA cluster status and the virulence of H. pylori in a littoral region of Northeast China. Two hundred and sixty-two H. pylori strains isolated from the chronic gastritis were examined to evaluate the dupA cluster status, cag PAI genes and vacA genotype using PCR and Western blot. Histopathologic evaluations of biopsy specimens were performed to analysis the association between the dupA cluster and the inflammatory response. IL-8 productions in gastric mucosa and from GES-1 cells co-cultured with H. pylori were measured, respectively, to analysis the association between the dupA cluster status and IL-8 production. We found that gastric mucosal inflammatory cell infiltration was significantly higher in patients with dupA-positive H. pylori, including H. pylori with complete dupA cluster (2.71 ± 0.79) and incomplete dupA cluster (2.09 ± 0.61) than in patients with dupA-negative strain (1.73 ± 0.60, p < 0.01), whereas no significant difference in the gastric mucosal atrophy was found according to the status of dupA cluster. Gastric mucosal IL-8 levels were higher in the complete dupA cluster group than in other groups (p < 0.01), and IL-8 production from GES-1 cells was also significantly higher in strains with a complete dupA cluster (1527.9 ± 180.0 pg/ml) than in those with an incomplete dupA cluster (1229.4 ± 75.3 pg/ml, p < 0.01) or those with dupA negative (1201.9 ± 92.3 pg/ml, p < 0.01). In conclusion, the complete dupA cluster in H. pylori is associated with inflammatory cell infiltration and IL-8 secretion, and H. pylori strain with a complete dupA cluster seems to be more virulent than other strains with the incomplete dupA cluster or dupA negative.

  10. Comparative genomics of ParaHox clusters of teleost fishes: gene cluster breakup and the retention of gene sets following whole genome duplications

    PubMed Central

    Siegel, Nicol; Hoegg, Simone; Salzburger, Walter; Braasch, Ingo; Meyer, Axel

    2007-01-01

    Background The evolutionary lineage leading to the teleost fish underwent a whole genome duplication termed FSGD or 3R in addition to two prior genome duplications that took place earlier during vertebrate evolution (termed 1R and 2R). Resulting from the FSGD, additional copies of genes are present in fish, compared to tetrapods whose lineage did not experience the 3R genome duplication. Interestingly, we find that ParaHox genes do not differ in number in extant teleost fishes despite their additional genome duplication from the genomic situation in mammals, but they are distributed over twice as many paralogous regions in fish genomes. Results We determined the DNA sequence of the entire ParaHox C1 paralogon in the East African cichlid fish Astatotilapia burtoni, and compared it to orthologous regions in other vertebrate genomes as well as to the paralogous vertebrate ParaHox D paralogons. Evolutionary relationships among genes from these four chromosomal regions were studied with several phylogenetic algorithms. We provide evidence that the genes of the ParaHox C paralogous cluster are duplicated in teleosts, just as it had been shown previously for the D paralogon genes. Overall, however, synteny and cluster integrity seems to be less conserved in ParaHox gene clusters than in Hox gene clusters. Comparative analyses of non-coding sequences uncovered conserved, possibly co-regulatory elements, which are likely to contain promoter motives of the genes belonging to the ParaHox paralogons. Conclusion There seems to be strong stabilizing selection for gene order as well as gene orientation in the ParaHox C paralogon, since with a few exceptions, only the lengths of the introns and intergenic regions differ between the distantly related species examined. The high degree of evolutionary conservation of this gene cluster's architecture in particular – but possibly clusters of genes more generally – might be linked to the presence of promoter, enhancer or inhibitor

  11. Early Transition Metal Oxides as Catalysts: Crossing Scales from Clusters to Single Crystals to Functioning Materials

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lai-Sheng Wang

    2009-07-07

    The overall goal of this program is to investigate the electronic structure and chemical bonding of early transition metal oxide clusters and use them as well-defined molecular models to obtain insight into properties and mechanisms of oxide catalysts, as well as to provide accurate spectroscopic and molecular information to verify theoretical methods used to predict materials properties. A laser vaporization cluster source is used to produce metal oxide clusters with different sizes, structures, and compositions. Well-defined inorganic polyoxometalate clusters in solution are transported in the gas phase using electrospray. Two state-of-the-art photoelectron spectroscopy apparatuses are used to interrogate the oxidemore » clusters and polyoxometalate anions in the gas phase to obtain spectroscopic and electronic structure information. The experimental effort is assisted by theoretical calculations to understanding the structures, chemical bonding, and catalytical properties of the transition metal oxide clusters. The research approach combines novel and flexible experimental techniques and advanced theoretical/computational methodologies and seeks molecular-level information to aiding the design of new catalysts, as well as mechanistic understanding. We have focused on the investigation of tungsten oxide clusters containing three W atoms: W{sub 3}O{sub x}{sup -} (x = 7-11). A number of interesting findings have been made. We observed that the oxygen-poor W{sub 3}O8 cluster contains a localized W{sup 4+} center, which can be used as a molecular model for O-deficient defect sites. A chemisorption energy was obtained through density functional calculations for W{sub 3}O8 + O{sub 2} {yields} W{sub 3}O{sub 10} as -78 kcal/mol. We further found that the neutral stoichiometric W{sub 2}O{sub 6} and W{sub 3}O{sub 9} clusters do not react with O{sub 2} and they only form physi-sorbed complexes, W{sub 2}O{sub 6}(O{sub 2}) and W{sub 3}O{sub 9}(O{sub 2}). However, the

  12. The shape and size distribution of H II regions near the percolation transition

    NASA Astrophysics Data System (ADS)

    Bag, Satadru; Mondal, Rajesh; Sarkar, Prakash; Bharadwaj, Somnath; Sahni, Varun

    2018-06-01

    Using Shapefinders, which are ratios of Minkowski functionals, we study the morphology of neutral hydrogen (H I) density fields, simulated using seminumerical technique (inside-out), at various stages of reionization. Accompanying the Shapefinders, we also employ the `largest cluster statistic' (LCS), originally proposed in Klypin & Shandarin, to study the percolation in both neutral and ionized hydrogen. We find that the largest ionized region is percolating below the neutral fraction x_{H I}≲ 0.728 (or equivalently z ≲ 9). The study of Shapefinders reveals that the largest ionized region starts to become highly filamentary with non-trivial topology near the percolation transition. During the percolation transition, the first two Shapefinders - `thickness' (T) and `breadth' (B) - of the largest ionized region do not vary much, while the third Shapefinder - `length' (L) - abruptly increases. Consequently, the largest ionized region tends to be highly filamentary and topologically quite complex. The product of the first two Shapefinders, T × B, provides a measure of the `cross-section' of a filament-like ionized region. We find that, near percolation, the value of T × B for the largest ionized region remains stable at ˜7 Mpc2 (in comoving scale) while its length increases with time. Interestingly, all large ionized regions have similar cross-sections. However, their length shows a power-law dependence on their volume, L ∝ V0.72, at the onset of percolation.

  13. miR-17-92 Cluster Promotes Cholangiocarcinoma Growth

    PubMed Central

    Zhu, Hanqing; Han, Chang; Lu, Dongdong; Wu, Tong

    2015-01-01

    miR-17-92 is an oncogenic miRNA cluster implicated in the development of several cancers; however, it remains unknown whether the miR-17-92 cluster is able to regulate cholangiocarcinogenesis. This study was designed to investigate the biological functions and molecular mechanisms of the miR-17-92 cluster in cholangiocarcinoma. In situ hybridization and quantitative RT-PCR analysis showed that the miR-17-92 cluster is highly expressed in human cholangiocarcinoma cells compared with the nonneoplastic biliary epithelial cells. Forced overexpression of the miR-17-92 cluster or its members, miR-92a and miR-19a, in cultured human cholangiocarcinoma cells enhanced tumor cell proliferation, colony formation, and invasiveness, in vitro. Overexpression of the miR-17-92 cluster or miR-92a also enhanced cholangiocarcinoma growth in vivo in hairless outbred mice with severe combined immunodeficiency (SHO-PrkdcscidHrhr). The tumor-suppressor, phosphatase and tensin homolog deleted on chromosome 10 (PTEN), was identified as a bona fide target of both miR-92a and miR-19a in cholangiocarcinoma cells via sequence prediction, 3′ untranslated region luciferase activity assay, and Western blot analysis. Accordingly, overexpression of the PTEN open reading frame protein (devoid of 3′ untranslated region) prevented miR-92a– or miR-19a–induced cholangiocarcinoma cell growth. Microarray analysis revealed additional targets of the miR-17-92 cluster in human cholangiocarcinoma cells, including APAF-1 and PRDM2. Moreover, we observed that the expression of the miR-17-92 cluster is regulated by IL-6/Stat3, a key oncogenic signaling pathway pivotal in cholangiocarcinogenesis. Taken together, our findings disclose a novel IL-6/Stat3–miR-17-92 cluster–PTEN signaling axis that is crucial for cholangiocarcinogenesis and tumor progression. PMID:25239565

  14. Nucleation of Hydrogen Deficient Carbon Clusters in Circumstellar Envelopes of Carbon Stars

    NASA Astrophysics Data System (ADS)

    Chiong, C. C.; Asvany, O.; Balucani, N.; Lee, Y. T.; Kaiser, R. I.

    2001-04-01

    Hydrogen deficient carbon clusters HCn and H2Cn are thought to resemble the crucial link between naked carbon clusters such as C2/C3, polycyclic aromatic hydrocarbons, and carbon rich interstellar/circumstellar grains. To fully understand the astrophysical significance of these grain nuclei condensation processes, it is of paramount significance to elucidate first detailed mechanism how these simple precursors are formed in outflow of carbon rich stars. Due to this importance, we initiated in our laboratory a systematic research program to investigate reactions of C2 and C3 clusters in their singlet X1Σg+ ground state with unsaturated hydrocarbons C2H2 and C2H4 employing the crossed molecular beam technique. These experiments yield the first doubly differential reactive cross section on the cluster versus H/H2 exchange and supply valuable information on the stepwise growth of carbon rich structures in extraterrestrial environments. Preliminary data analyses identify the CCCCH, CCCCH, and CCCCH2 isomers which were identified in the circumstellar shell of IRC+10216 together with hitherto unobserved interstellar n-C4H3, n-C5H3, and CCCCCH2 radicals.

  15. Explanatory characteristics for nutrient concentrations and loads in the Sava River Catchment and cross-regionally

    NASA Astrophysics Data System (ADS)

    Levi, L.; Cvetkovic, V.; Destouni, G.

    2015-12-01

    This study compiles estimates of waterborne nutrient concentrations and loads in the Sava River Catchment (SRC). Based on this compilation, we investigate hotspots of nutrient inputs and retention along the river, as well as concentration and load correlations with river discharge and various human drivers of excess nutrient inputs to the SRC. For cross-regional assessment and possible generalization, we also compare corresponding results between the SRC and the Baltic Sea Drainage Basin (BSDB). In the SRC, one small incremental subcatchment, which is located just downstream of Zagreb and has the highest population density among the SRC subcatchments, is identified as a major hotspot for net loading (input minus retention) of both total nitrogen (TN) and total phosphorus (TP) to the river and through it to downstream areas of the SRC. The other SRC subcatchments exhibit relatively similar characteristics with smaller net nutrient loading. The annual loads of both TN and TP along the Sava River exhibit dominant temporal variability with considerably higher correlation with annual river discharge (R2 = 0.51 and 0.28, respectively) than that of annual average nutrient concentrations (R2 = 0.0 versus discharge for both TN and TP). Nutrient concentrations exhibit instead dominant spatial variability with relatively high correlation with population density among the SRC subcatchments (R2=0.43-0.64). These SRC correlation characteristics compare well with corresponding ones for the BSDB, even though the two regions are quite different in their hydroclimatic, agricultural and wastewater treatment conditions. Such cross-regional consistency in dominant variability type and explanatory catchment characteristics may be a useful generalization basis, worthy of further investigation, for at least first-order estimation of nutrient concentration and load conditions in less data-rich regions.

  16. Entanglement Concentration for Arbitrary Four-Photon Cluster State Assisted with Single Photons

    NASA Astrophysics Data System (ADS)

    Zhao, Sheng-Yang; Cai, Chun; Liu, Jiong; Zhou, Lan; Sheng, Yu-Bo

    2016-02-01

    We present an entanglement concentration protocol (ECP) to concentrate arbitrary four-photon less-entangled cluster state into maximally entangled cluster state. Different from other ECPs for cluster state, we only exploit the single photon as auxiliary, which makes this protocol feasible and economic. In our ECP, the concentrated maximally entangled state can be retained for further application and the discarded state can be reused for a higher success probability. This ECP works with the help of cross-Kerr nonlinearity and conventional photon detectors. This ECP may be useful in future one-way quantum computation.

  17. The Fornax Cluster VLT Spectroscopic Survey II - Planetary Nebulae kinematics within 200 kpc of the cluster core

    NASA Astrophysics Data System (ADS)

    Spiniello, C.; Napolitano, N. R.; Arnaboldi, M.; Tortora, C.; Coccato, L.; Capaccioli, M.; Gerhard, O.; Iodice, E.; Spavone, M.; Cantiello, M.; Peletier, R.; Paolillo, M.; Schipani, P.

    2018-06-01

    We present the largest and most spatially extended planetary nebulae (PNe) catalogue ever obtained for the Fornax cluster. We measured velocities of 1452 PNe out to 200 kpc in the cluster core using a counter-dispersed slitless spectroscopic technique with data from FORS2 on the Very Large Telescope (VLT). With such an extended spatial coverage, we can study separately the stellar haloes of some of the cluster main galaxies and the intracluster light. In this second paper of the Fornax Cluster VLT Spectroscopic Survey, we identify and classify the emission-line sources, describe the method to select PNe, and calculate their coordinates and velocities from the dispersed slitless images. From the PN 2D velocity map, we identify stellar streams that are possibly tracing the gravitational interaction of NGC 1399 with NGC 1404 and NGC 1387. We also present the velocity dispersion profile out to ˜200 kpc radii, which shows signatures of a superposition of the bright central galaxy and the cluster potential, with the latter clearly dominating the regions outside R ˜ 1000 arcsec (˜100 kpc).

  18. Clustering of health-related behaviors, health outcomes and demographics in Dutch adolescents: a cross-sectional study.

    PubMed

    Busch, Vincent; Van Stel, Henk F; Schrijvers, Augustinus J P; de Leeuw, Johannes R J

    2013-12-04

    Recent studies show several health-related behaviors to cluster in adolescents. This has important implications for public health. Interrelated behaviors have been shown to be most effectively targeted by multimodal interventions addressing wider-ranging improvements in lifestyle instead of via separate interventions targeting individual behaviors. However, few previous studies have taken into account a broad, multi-disciplinary range of health-related behaviors and connected these behavioral patterns to health-related outcomes. This paper presents an analysis of the clustering of a broad range of health-related behaviors with relevant demographic factors and several health-related outcomes in adolescents. Self-report questionnaire data were collected from a sample of 2,690 Dutch high school adolescents. Behavioral patterns were deducted via Principal Components Analysis. Subsequently a Two-Step Cluster Analysis was used to identify groups of adolescents with similar behavioral patterns and health-related outcomes. Four distinct behavioral patterns describe the analyzed individual behaviors: 1- risk-prone behavior, 2- bully behavior, 3- problematic screen time use, and 4- sedentary behavior. Subsequent cluster analysis identified four clusters of adolescents. Multi-problem behavior was associated with problematic physical and psychosocial health outcomes, as opposed to those exerting relatively few unhealthy behaviors. These associations were relatively independent of demographics such as ethnicity, gender and socio-economic status. The results show that health-related behaviors tend to cluster, indicating that specific behavioral patterns underlie individual health behaviors. In addition, specific patterns of health-related behaviors were associated with specific health outcomes and demographic factors. In general, unhealthy behavior on account of multiple health-related behaviors was associated with both poor psychosocial and physical health. These findings have

  19. Clustering of health-related behaviors, health outcomes and demographics in Dutch adolescents: a cross-sectional study

    PubMed Central

    2013-01-01

    Background Recent studies show several health-related behaviors to cluster in adolescents. This has important implications for public health. Interrelated behaviors have been shown to be most effectively targeted by multimodal interventions addressing wider-ranging improvements in lifestyle instead of via separate interventions targeting individual behaviors. However, few previous studies have taken into account a broad, multi-disciplinary range of health-related behaviors and connected these behavioral patterns to health-related outcomes. This paper presents an analysis of the clustering of a broad range of health-related behaviors with relevant demographic factors and several health-related outcomes in adolescents. Methods Self-report questionnaire data were collected from a sample of 2,690 Dutch high school adolescents. Behavioral patterns were deducted via Principal Components Analysis. Subsequently a Two-Step Cluster Analysis was used to identify groups of adolescents with similar behavioral patterns and health-related outcomes. Results Four distinct behavioral patterns describe the analyzed individual behaviors: 1- risk-prone behavior, 2- bully behavior, 3- problematic screen time use, and 4- sedentary behavior. Subsequent cluster analysis identified four clusters of adolescents. Multi-problem behavior was associated with problematic physical and psychosocial health outcomes, as opposed to those exerting relatively few unhealthy behaviors. These associations were relatively independent of demographics such as ethnicity, gender and socio-economic status. Conclusions The results show that health-related behaviors tend to cluster, indicating that specific behavioral patterns underlie individual health behaviors. In addition, specific patterns of health-related behaviors were associated with specific health outcomes and demographic factors. In general, unhealthy behavior on account of multiple health-related behaviors was associated with both poor psychosocial

  20. Construction of a restriction map and gene map of the lettuce chloroplast small single-copy region using Southern cross-hybridization.

    PubMed

    Mitchelson, K R

    1996-01-01

    The small single-copy region (SSCR) of the chloroplast genome of many higher plants typically contain ndh genes encoding proteins that share homology with subunits of the respiratory-chain reduced nicotinamide adenine dinucleotide (NADH) dehydrogenase complex of mitochondria. A map of the lettuce chloroplast SSCR has been determined by Southern cross-hybridization, taking advantage of the high degree of homology between a tobacco small single-copy fragment and a corresponding lettuce chloroplast fragment. The gene order of the SSCR of lettuce and tobacco chloroplasts is similar. The cross-hybridization method can rapidly create a primary gene map of unknown chloroplast fragments, thus providing detailed information of the localization and arrangement of genes and conserved open reading frame regions.

  1. Classical plasma dynamics of Mie-oscillations in atomic clusters

    NASA Astrophysics Data System (ADS)

    Kull, H.-J.; El-Khawaldeh, A.

    2018-04-01

    Mie plasmons are of basic importance for the absorption of laser light by atomic clusters. In this work we first review the classical Rayleigh-theory of a dielectric sphere in an external electric field and Thomson’s plum-pudding model applied to atomic clusters. Both approaches allow for elementary discussions of Mie oscillations, however, they also indicate deficiencies in describing the damping mechanisms by electrons crossing the cluster surface. Nonlinear oscillator models have been widely studied to gain an understanding of damping and absorption by outer ionization of the cluster. In the present work, we attempt to address the issue of plasmon relaxation in atomic clusters in more detail based on classical particle simulations. In particular, we wish to study the role of thermal motion on plasmon relaxation, thereby extending nonlinear models of collective single-electron motion. Our simulations are particularly adopted to the regime of classical kinetics in weakly coupled plasmas and to cluster sizes extending the Debye-screening length. It will be illustrated how surface scattering leads to the relaxation of Mie oscillations in the presence of thermal motion and of electron spill-out at the cluster surface. This work is intended to give, from a classical perspective, further insight into recent work on plasmon relaxation in quantum plasmas [1].

  2. Characterization of a Large Cluster of Influenza A(H1N1)pdm09 Viruses Cross-Resistant to Oseltamivir and Peramivir during the 2013-2014 Influenza Season in Japan

    PubMed Central

    Takashita, Emi; Kiso, Maki; Fujisaki, Seiichiro; Yokoyama, Masaru; Nakamura, Kazuya; Shirakura, Masayuki; Sato, Hironori; Odagiri, Takato; Kawaoka, Yoshihiro

    2015-01-01

    Between September 2013 and July 2014, 2,482 influenza 2009 pandemic A(H1N1) [A(H1N1)pdm09] viruses were screened in Japan for the H275Y substitution in their neuraminidase (NA) protein, which confers cross-resistance to oseltamivir and peramivir. We found that a large cluster of the H275Y mutant virus was present prior to the main influenza season in Sapporo/Hokkaido, with the detection rate for this mutant virus reaching 29% in this area. Phylogenetic analysis suggested the clonal expansion of a single mutant virus in Sapporo/Hokkaido. To understand the reason for this large cluster, we examined the in vitro and in vivo properties of the mutant virus. We found that it grew well in cell culture, with growth comparable to that of the wild-type virus. The cluster virus also replicated well in the upper respiratory tract of ferrets and was transmitted efficiently between ferrets by way of respiratory droplets. Almost all recently circulating A(H1N1)pdm09 viruses, including the cluster virus, possessed two substitutions in NA, V241I and N369K, which are known to increase replication and transmission fitness. A structural analysis of NA predicted that a third substitution (N386K) in the NA of the cluster virus destabilized the mutant NA structure in the presence of the V241I and N369K substitutions. Our results suggest that the cluster virus retained viral fitness to spread among humans and, accordingly, caused the large cluster in Sapporo/Hokkaido. However, the mutant NA structure was less stable than that of the wild-type virus. Therefore, once the wild-type virus began to circulate in the community, the mutant virus could not compete and faded out. PMID:25691635

  3. New VVV Survey Globular Cluster Candidates in the Milky Way Bulge

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Minniti, Dante; Gómez, Matías; Geisler, Douglas

    It is likely that a number of Galactic globular clusters remain to be discovered, especially toward the Galactic bulge. High stellar density combined with high and differential interstellar reddening are the two major problems for finding globular clusters located toward the bulge. We use the deep near-IR photometry of the VISTA Variables in the Vía Láctea (VVV) Survey to search for globular clusters projected toward the Galactic bulge, and hereby report the discovery of 22 new candidate globular clusters. These objects, detected as high density regions in our maps of bulge red giants, are confirmed as globular cluster candidates bymore » their color–magnitude diagrams. We provide their coordinates as well as their near-IR color–magnitude diagrams, from which some basic parameters are derived, such as reddenings and heliocentric distances. The color–magnitude diagrams reveal well defined red giant branches in all cases, often including a prominent red clump. The new globular cluster candidates exhibit a variety of extinctions (0.06 < A {sub Ks} < 2.77) and distances (5.3 < D < 9.5 kpc). We also classify the globular cluster candidates into 10 metal-poor and 12 metal-rich clusters, based on the comparison of their color–magnitude diagrams with those of known globular clusters also observed by the VVV Survey. Finally, we argue that the census for Galactic globular clusters still remains incomplete, and that many more candidate globular clusters (particularly the low luminosity ones) await to be found and studied in detail in the central regions of the Milky Way.« less

  4. Symptom Clusters in People Living with HIV Attending Five Palliative Care Facilities in Two Sub-Saharan African Countries: A Hierarchical Cluster Analysis.

    PubMed

    Moens, Katrien; Siegert, Richard J; Taylor, Steve; Namisango, Eve; Harding, Richard

    2015-01-01

    Symptom research across conditions has historically focused on single symptoms, and the burden of multiple symptoms and their interactions has been relatively neglected especially in people living with HIV. Symptom cluster studies are required to set priorities in treatment planning, and to lessen the total symptom burden. This study aimed to identify and compare symptom clusters among people living with HIV attending five palliative care facilities in two sub-Saharan African countries. Data from cross-sectional self-report of seven-day symptom prevalence on the 32-item Memorial Symptom Assessment Scale-Short Form were used. A hierarchical cluster analysis was conducted using Ward's method applying squared Euclidean Distance as the similarity measure to determine the clusters. Contingency tables, X2 tests and ANOVA were used to compare the clusters by patient specific characteristics and distress scores. Among the sample (N=217) the mean age was 36.5 (SD 9.0), 73.2% were female, and 49.1% were on antiretroviral therapy (ART). The cluster analysis produced five symptom clusters identified as: 1) dermatological; 2) generalised anxiety and elimination; 3) social and image; 4) persistently present; and 5) a gastrointestinal-related symptom cluster. The patients in the first three symptom clusters reported the highest physical and psychological distress scores. Patient characteristics varied significantly across the five clusters by functional status (worst functional physical status in cluster one, p<0.001); being on ART (highest proportions for clusters two and three, p=0.012); global distress (F=26.8, p<0.001), physical distress (F=36.3, p<0.001) and psychological distress subscale (F=21.8, p<0.001) (all subscales worst for cluster one, best for cluster four). The greatest burden is associated with cluster one, and should be prioritised in clinical management. Further symptom cluster research in people living with HIV with longitudinally collected symptom data to

  5. Shock Heating of the Merging Galaxy Cluster A521

    NASA Technical Reports Server (NTRS)

    Bourdin, H.; Mazzotta, P.; Markevitch, M.; Giacintucci, S.; Brunetti, G.

    2013-01-01

    A521 is an interacting galaxy cluster located at z = 0.247, hosting a low-frequency radio halo connected to an eastern radio relic. Previous Chandra observations hinted at the presence of an X-ray brightness edge at the position of the relic, which may be a shock front. We analyze a deep observation of A521 recently performed with XMM-Newton in order to probe the cluster structure up to the outermost regions covered by the radio emission. The cluster atmosphere exhibits various brightness and temperature anisotropies. In particular, two cluster cores appear to be separated by two cold fronts. We find two shock fronts, one that was suggested by Chandra and that is propagating to the east, and another to the southwestern cluster outskirt. The two main interacting clusters appear to be separated by a shock-heated region, which exhibits a spatial correlation with the radio halo. The outer edge of the radio relic coincides spatially with a shock front, suggesting that this shock is responsible for the generation of cosmic-ray electrons in the relic. The propagation direction and Mach number of the shock front derived from the gas density jump, M = 2.4 +/- 0.2, are consistent with expectations from the radio spectral index, under the assumption of Fermi I acceleration mechanism.

  6. Mapping Emission from Clusters of CdSe/ZnS Nanoparticles

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ryan, Duncan P.; Goodwin, Peter M.; Sheehan, Chris J.

    In this paper, we have carried out correlated super-resolution and SEM imaging studies of clusters of CdSe/ZnS nanoparticles containing up to ten particles to explore how the fluorescence behavior of these clusters depends on the number of particles, the specific cluster geometry, the shell thickness, and the technique used to produce the clusters. The total emission yield was less than proportional to the number of particles in the clusters for both thick and thin shells. With super-resolution imaging, the emission center of the cluster could be spatially resolved at distance scales on the order of the cluster size. The intrinsicmore » fluorescence intermittency of the nanoparticles altered the emission distribution across the cluster, which enabled the identification of relative emission intensities of individual particles or small groups of particles within the cluster. Finally, for clusters undergoing interparticle energy transfer, donor/acceptor pairs and regions where energy was funneled could be identified.« less

  7. Mapping Emission from Clusters of CdSe/ZnS Nanoparticles

    DOE PAGES

    Ryan, Duncan P.; Goodwin, Peter M.; Sheehan, Chris J.; ...

    2018-01-24

    In this paper, we have carried out correlated super-resolution and SEM imaging studies of clusters of CdSe/ZnS nanoparticles containing up to ten particles to explore how the fluorescence behavior of these clusters depends on the number of particles, the specific cluster geometry, the shell thickness, and the technique used to produce the clusters. The total emission yield was less than proportional to the number of particles in the clusters for both thick and thin shells. With super-resolution imaging, the emission center of the cluster could be spatially resolved at distance scales on the order of the cluster size. The intrinsicmore » fluorescence intermittency of the nanoparticles altered the emission distribution across the cluster, which enabled the identification of relative emission intensities of individual particles or small groups of particles within the cluster. Finally, for clusters undergoing interparticle energy transfer, donor/acceptor pairs and regions where energy was funneled could be identified.« less

  8. Carbon atom and cluster sputtering under low-energy noble gas plasma bombardment

    NASA Astrophysics Data System (ADS)

    Oyarzabal, E.; Doerner, R. P.; Shimada, M.; Tynan, G. R.

    2008-08-01

    Exit-angle resolved carbon atom and cluster (C2 and C3) sputtering yields are measured during different noble gas (Xe, Kr, Ar, Ne, and He) ion bombardments from a plasma, for low incident energies (75-225 eV). A quadrupole mass spectrometer (QMS) is used to detect the fraction of sputtered neutrals that is ionized in the plasma and to obtain the angular distribution by changing the angle between the target normal and the QMS aperture. A one-dimensional Monte Carlo code is used to simulate the interaction of the plasma and the sputtered particles in the region between the sample and the QMS. The effective elastic scattering cross sections of C, C2, and C3 with the different bombarding gas neutrals are obtained by varying the distance between the sample and the QMS and by performing a best fit of the simulation results to the experimental results. The total sputtering yield (C+C2+C3) for each bombarding gas is obtained from weight-loss measurements and the sputtering yield for C, C2, and C3 is then calculated from the integration of the measured angular distribution, taking into account the scattering and ionization of the sputtered particles between the sample and the QMS. We observe undercosine angular distributions of the sputtered atoms and clusters for all the studied bombarding gases and a clear decrease of the atom to cluster (C2 and C3) sputtering ratio as the incident ion mass increases, changing from a carbon atom preferential erosion for the lower incident ion masses (He, Ne, and Ar) to a cluster preferential erosion for the higher incident ion masses (Kr and Xe).

  9. Cerebellar Functional Parcellation Using Sparse Dictionary Learning Clustering.

    PubMed

    Wang, Changqing; Kipping, Judy; Bao, Chenglong; Ji, Hui; Qiu, Anqi

    2016-01-01

    The human cerebellum has recently been discovered to contribute to cognition and emotion beyond the planning and execution of movement, suggesting its functional heterogeneity. We aimed to identify the functional parcellation of the cerebellum using information from resting-state functional magnetic resonance imaging (rs-fMRI). For this, we introduced a new data-driven decomposition-based functional parcellation algorithm, called Sparse Dictionary Learning Clustering (SDLC). SDLC integrates dictionary learning, sparse representation of rs-fMRI, and k-means clustering into one optimization problem. The dictionary is comprised of an over-complete set of time course signals, with which a sparse representation of rs-fMRI signals can be constructed. Cerebellar functional regions were then identified using k-means clustering based on the sparse representation of rs-fMRI signals. We solved SDLC using a multi-block hybrid proximal alternating method that guarantees strong convergence. We evaluated the reliability of SDLC and benchmarked its classification accuracy against other clustering techniques using simulated data. We then demonstrated that SDLC can identify biologically reasonable functional regions of the cerebellum as estimated by their cerebello-cortical functional connectivity. We further provided new insights into the cerebello-cortical functional organization in children.

  10. Computer-aided detection of breast lesions in DCE-MRI using region growing based on fuzzy C-means clustering and vesselness filter

    NASA Astrophysics Data System (ADS)

    B. Shokouhi, Shahriar; Fooladivanda, Aida; Ahmadinejad, Nasrin

    2017-12-01

    A computer-aided detection (CAD) system is introduced in this paper for detection of breast lesions in dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI). The proposed CAD system firstly compensates motion artifacts and segments the breast region. Then, the potential lesion voxels are detected and used as the initial seed points for the seeded region-growing algorithm. A new and robust region-growing algorithm incorporating with Fuzzy C-means (FCM) clustering and vesselness filter is proposed to segment any potential lesion regions. Subsequently, the false positive detections are reduced by applying a discrimination step. This is based on 3D morphological characteristics of the potential lesion regions and kinetic features which are fed to the support vector machine (SVM) classifier. The performance of the proposed CAD system is evaluated using the free-response operating characteristic (FROC) curve. We introduce our collected dataset that includes 76 DCE-MRI studies, 63 malignant and 107 benign lesions. The prepared dataset has been used to verify the accuracy of the proposed CAD system. At 5.29 false positives per case, the CAD system accurately detects 94% of the breast lesions.

  11. LOW-METALLICITY YOUNG CLUSTERS IN THE OUTER GALAXY. II. SH 2-208

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Yasui, Chikako; Kobayashi, Naoto; Izumi, Natsuko

    We obtained deep near-infrared images of Sh 2-208, one of the lowest-metallicity H ii regions in the Galaxy, [O/H] = −0.8 dex. We detected a young cluster in the center of the H ii region with a limiting magnitude of K = 18.0 mag (10 σ ), which corresponds to a mass detection limit of ∼0.2 M {sub ⊙}. This enables the comparison of star-forming properties under low metallicity with those of the solar neighborhood. We identified 89 cluster members. From the fitting of the K -band luminosity function (KLF), the age and distance of the cluster are estimated to be ∼0.5more » Myr and ∼4 kpc, respectively. The estimated young age is consistent with the detection of strong CO emission in the cluster region and the estimated large extinction of cluster members ( A{sub V}  ∼ 4–25 mag). The observed KLF suggests that the underlying initial mass function (IMF) of the low-metallicity cluster is not significantly different from canonical IMFs in the solar neighborhood in terms of both high-mass slope and IMF peak (characteristic mass). Despite the very young age, the disk fraction of the cluster is estimated at only 27% ± 6%, which is significantly lower than those in the solar metallicity. Those results are similar to Sh 2-207, which is another star-forming region close to Sh 2-208 with a separation of 12 pc, suggesting that their star-forming activities in low-metallicity environments are essentially identical to those in the solar neighborhood, except for the disk dispersal timescale. From large-scale mid-infrared images, we suggest that sequential star formation is taking place in Sh 2-207, Sh 2-208, and the surrounding region, triggered by an expanding bubble with a ∼30 pc radius.« less

  12. Clustering of European winter storms: A multi-model perspective

    NASA Astrophysics Data System (ADS)

    Renggli, Dominik; Buettner, Annemarie; Scherb, Anke; Straub, Daniel; Zimmerli, Peter

    2016-04-01

    The storm series over Europe in 1990 (Daria, Vivian, Wiebke, Herta) and 1999 (Anatol, Lothar, Martin) are very well known. Such clusters of severe events strongly affect the seasonally accumulated damage statistics. The (re)insurance industry has quantified clustering by using distribution assumptions deduced from the historical storm activity of the last 30 to 40 years. The use of storm series simulated by climate models has only started recently. Climate model runs can potentially represent 100s to 1000s of years, allowing a more detailed quantification of clustering than the history of the last few decades. However, it is unknown how sensitive the representation of clustering is to systematic biases. Using a multi-model ensemble allows quantifying that uncertainty. This work uses CMIP5 decadal ensemble hindcasts to study clustering of European winter storms from a multi-model perspective. An objective identification algorithm extracts winter storms (September to April) in the gridded 6-hourly wind data. Since the skill of European storm predictions is very limited on the decadal scale, the different hindcast runs are interpreted as independent realizations. As a consequence, the available hindcast ensemble represents several 1000 simulated storm seasons. The seasonal clustering of winter storms is quantified using the dispersion coefficient. The benchmark for the decadal prediction models is the 20th Century Reanalysis. The decadal prediction models are able to reproduce typical features of the clustering characteristics observed in the reanalysis data. Clustering occurs in all analyzed models over the North Atlantic and European region, in particular over Great Britain and Scandinavia as well as over Iberia (i.e. the exit regions of the North Atlantic storm track). Clustering is generally weaker in the models compared to reanalysis, although the differences between different models are substantial. In contrast to existing studies, clustering is driven by weak

  13. Heterogeneous Tensor Decomposition for Clustering via Manifold Optimization.

    PubMed

    Sun, Yanfeng; Gao, Junbin; Hong, Xia; Mishra, Bamdev; Yin, Baocai

    2016-03-01

    Tensor clustering is an important tool that exploits intrinsically rich structures in real-world multiarray or Tensor datasets. Often in dealing with those datasets, standard practice is to use subspace clustering that is based on vectorizing multiarray data. However, vectorization of tensorial data does not exploit complete structure information. In this paper, we propose a subspace clustering algorithm without adopting any vectorization process. Our approach is based on a novel heterogeneous Tucker decomposition model taking into account cluster membership information. We propose a new clustering algorithm that alternates between different modes of the proposed heterogeneous tensor model. All but the last mode have closed-form updates. Updating the last mode reduces to optimizing over the multinomial manifold for which we investigate second order Riemannian geometry and propose a trust-region algorithm. Numerical experiments show that our proposed algorithm compete effectively with state-of-the-art clustering algorithms that are based on tensor factorization.

  14. Spatial cluster detection for repeatedly measured outcomes while accounting for residential history.

    PubMed

    Cook, Andrea J; Gold, Diane R; Li, Yi

    2009-10-01

    Spatial cluster detection has become an important methodology in quantifying the effect of hazardous exposures. Previous methods have focused on cross-sectional outcomes that are binary or continuous. There are virtually no spatial cluster detection methods proposed for longitudinal outcomes. This paper proposes a new spatial cluster detection method for repeated outcomes using cumulative geographic residuals. A major advantage of this method is its ability to readily incorporate information on study participants relocation, which most cluster detection statistics cannot. Application of these methods will be illustrated by the Home Allergens and Asthma prospective cohort study analyzing the relationship between environmental exposures and repeated measured outcome, occurrence of wheeze in the last 6 months, while taking into account mobile locations.

  15. Global detection approach for clustered microcalcifications in mammograms using a deep learning network.

    PubMed

    Wang, Juan; Nishikawa, Robert M; Yang, Yongyi

    2017-04-01

    In computerized detection of clustered microcalcifications (MCs) from mammograms, the traditional approach is to apply a pattern detector to locate the presence of individual MCs, which are subsequently grouped into clusters. Such an approach is often susceptible to the occurrence of false positives (FPs) caused by local image patterns that resemble MCs. We investigate the feasibility of a direct detection approach to determining whether an image region contains clustered MCs or not. Toward this goal, we develop a deep convolutional neural network (CNN) as the classifier model to which the input consists of a large image window ([Formula: see text] in size). The multiple layers in the CNN classifier are trained to automatically extract image features relevant to MCs at different spatial scales. In the experiments, we demonstrated this approach on a dataset consisting of both screen-film mammograms and full-field digital mammograms. We evaluated the detection performance both on classifying image regions of clustered MCs using a receiver operating characteristic (ROC) analysis and on detecting clustered MCs from full mammograms by a free-response receiver operating characteristic analysis. For comparison, we also considered a recently developed MC detector with FP suppression. In classifying image regions of clustered MCs, the CNN classifier achieved 0.971 in the area under the ROC curve, compared to 0.944 for the MC detector. In detecting clustered MCs from full mammograms, at 90% sensitivity, the CNN classifier obtained an FP rate of 0.69 clusters/image, compared to 1.17 clusters/image by the MC detector. These results indicate that using global image features can be more effective in discriminating clustered MCs from FPs caused by various sources, such as linear structures, thereby providing a more accurate detection of clustered MCs on mammograms.

  16. LoCuSS: The infall of X-ray groups on to massive clusters

    NASA Astrophysics Data System (ADS)

    Haines, C. P.; Finoguenov, A.; Smith, G. P.; Babul, A.; Egami, E.; Mazzotta, P.; Okabe, N.; Pereira, M. J.; Bianconi, M.; McGee, S. L.; Ziparo, F.; Campusano, L. E.; Loyola, C.

    2018-07-01

    Galaxy clusters are expected to form hierarchically in a Λ cold dark matter (ΛCDM) universe, growing primarily through mergers with lower mass clusters and the continual accretion of group-mass haloes. Galaxy clusters assemble late, doubling their masses since z ˜ 0.5, and so the outer regions of clusters should be replete with accreting group-mass systems. We present an XMM-Newton survey to search for X-ray groups in the infall regions of 23 massive galaxy clusters ( ˜ 1015 M⊙) at z ˜ 0.2, identifying 39 X-ray groups that have been spectroscopically confirmed to lie at the cluster redshift. These groups have mass estimates in the range 2 × 1013-7 × 1014 M⊙, and group-to-cluster mass ratios as low as 0.02. The comoving number density of X-ray groups in the infall regions is ˜25× higher than that seen for isolated X-ray groups from the XXL survey. The average mass per cluster contained within these X-ray groups is 2.2 × 1014 M⊙, or 19 ± 5 per cent of the mass within the primary cluster itself. We estimate that ˜1015 M⊙ clusters increase their masses by 16 ± 4 per cent between z = 0.223 and the present day due to the accretion of groups with M200 ≥ 1013.2 M⊙. This represents about half of the expected mass growth rate of clusters at these late epochs. The other half is likely to come from smooth accretion of matter not bound within haloes. The mass function of the infalling X-ray groups appears significantly top heavy with respect to that of `field' X-ray systems, consistent with expectations from numerical simulations, and the basic consequences of collapsed massive dark matter haloes being biased tracers of the underlying large-scale density distribution.

  17. A new open cluster binary system in the Milky Way

    NASA Astrophysics Data System (ADS)

    Piatti, A. E.; Clariá, J. J.; Ahumada, A. V.

    2011-10-01

    We have obtained CCD UBVI_{KC} photometry for the open clusters (OCs) Hogg 12 and NGC 3590. Based on photometric and morphological criteria, as well as on the stellar density in the region, our evidence is sufficient to consider them a new open cluster binary system candidate.

  18. Exponents of non-linear clustering in scale-free one-dimensional cosmological simulations

    NASA Astrophysics Data System (ADS)

    Benhaiem, David; Joyce, Michael; Sicard, François

    2013-03-01

    One-dimensional versions of dissipationless cosmological N-body simulations have been shown to share many qualitative behaviours of the three-dimensional problem. Their interest lies in the fact that they can resolve a much greater range of time and length scales, and admit exact numerical integration. We use such models here to study how non-linear clustering depends on initial conditions and cosmology. More specifically, we consider a family of models which, like the three-dimensional Einstein-de Sitter (EdS) model, lead for power-law initial conditions to self-similar clustering characterized in the strongly non-linear regime by power-law behaviour of the two-point correlation function. We study how the corresponding exponent γ depends on the initial conditions, characterized by the exponent n of the power spectrum of initial fluctuations, and on a single parameter κ controlling the rate of expansion. The space of initial conditions/cosmology divides very clearly into two parts: (1) a region in which γ depends strongly on both n and κ and where it agrees very well with a simple generalization of the so-called stable clustering hypothesis in three dimensions; and (2) a region in which γ is more or less independent of both the spectrum and the expansion of the universe. The boundary in (n, κ) space dividing the `stable clustering' region from the `universal' region is very well approximated by a `critical' value of the predicted stable clustering exponent itself. We explain how this division of the (n, κ) space can be understood as a simple physical criterion which might indeed be expected to control the validity of the stable clustering hypothesis. We compare and contrast our findings to results in three dimensions, and discuss in particular the light they may throw on the question of `universality' of non-linear clustering in this context.

  19. Sample size calculation for stepped wedge and other longitudinal cluster randomised trials.

    PubMed

    Hooper, Richard; Teerenstra, Steven; de Hoop, Esther; Eldridge, Sandra

    2016-11-20

    The sample size required for a cluster randomised trial is inflated compared with an individually randomised trial because outcomes of participants from the same cluster are correlated. Sample size calculations for longitudinal cluster randomised trials (including stepped wedge trials) need to take account of at least two levels of clustering: the clusters themselves and times within clusters. We derive formulae for sample size for repeated cross-section and closed cohort cluster randomised trials with normally distributed outcome measures, under a multilevel model allowing for variation between clusters and between times within clusters. Our formulae agree with those previously described for special cases such as crossover and analysis of covariance designs, although simulation suggests that the formulae could underestimate required sample size when the number of clusters is small. Whether using a formula or simulation, a sample size calculation requires estimates of nuisance parameters, which in our model include the intracluster correlation, cluster autocorrelation, and individual autocorrelation. A cluster autocorrelation less than 1 reflects a situation where individuals sampled from the same cluster at different times have less correlated outcomes than individuals sampled from the same cluster at the same time. Nuisance parameters could be estimated from time series obtained in similarly clustered settings with the same outcome measure, using analysis of variance to estimate variance components. Copyright © 2016 John Wiley & Sons, Ltd. Copyright © 2016 John Wiley & Sons, Ltd.

  20. Constraining the Mass of the Spectacular Pandora's Cluster, Abell 2744

    NASA Astrophysics Data System (ADS)

    Carrasco, Rodrigo; Frye, Brenda; Coe, Dan; Dupke, Renato; Merten, Julian; Sodre, Laerte; Massey, Richard; Braglia, Filberto; Cypriano, Eduardo; Zitrin, Adi; Krick, Jessica; Benitez, Narciso

    2011-08-01

    Violent cluster mergers provide a unique opportunity to study the interplay between dark matter (DM) and ICM and to set constraints on the nature of DM. In particular, cluster mergers near first core passage allow us to ``see'' DM by comparing the spatial distribution of the intra-cluster gas (baryonic) to that of DM. We have recently finished a lensing analysis of the particularly interesting merging system, A2744, the Pandora cluster. We found that it is the result of a spectacular merging event, significantly more complex than the "Bullet Cluster", that produced a wide variety of new phenomenologies, among them, a Bullet, a Dark sub-cluster (no gas), a Ghost sub-cluster (no DM), which can provide fundamental insights to the physics of the ICM, and begs further observations. Our analyses revealed 34 arcs produced by strong gravitational lensing, none of which had been published to date. Spectroscopic redshifts of these arcs are essential to determine precise masses of the main merging system providing crucial information for further numerical simulations and to set stronger constraints on the DM self-interaction cross-section. Therefore we are requesting 17.2 hours on Gemini+GMOS-S, primarily to obtain spectroscopic redshifts of multiply strongly lensed arcs produced by this impressive cluster.

  1. Nutrition, environment and cardiovascular health (NESCAV): protocol of an inter-regional cross-sectional study.

    PubMed

    Alkerwi, Ala'a; Guillaume, Michèle; Zannad, Faiez; Laufs, Ulrich; Lair, Marie-Lise

    2010-11-15

    Despite the remarkable technological progress in health care and treatment, cardiovascular disease remains the leading cause of premature death, prolonged hospitalization and disability in most European countries. In the population of the Greater Region (Grand-Duchy of Luxembourg, Wallonia in Belgium, and Lorraine in France), the prevalence of cardiovascular risk factors and disease is among the highest in Europe, warranting the need for a better understanding of factors contributing to this pattern. In this context, the cross-border "Nutrition, Environment and Cardiovascular Health-NESCAV" project is initiated by an inter-regional multi-disciplinary consortium and supported by the INTERREG IV A program "Greater Region", 2007-2013, to fight synergically and harmoniously against this major public health problem. The objectives of the three-year planned project are to assess, in a representative sample of 3000 randomly selected individuals living at the Greater Region, 1) the cardiovascular health and risk profile, 2) the association between the dietary habits and the cardiovascular risk, 3) the association of occupational and environmental pollution markers with the cardiovascular risk, 4) the knowledge, awareness and level of control of cardiovascular risk factors, 5) the potential gaps in the current primary prevention, and finally, to address evidence-based recommendations enabling the development of inter-regional guidance to help policy-makers and health care workers for the prevention of cardiovascular disease. The findings will provide tools that may enable the Greater Region's decision-makers and health professionals to implement targeted and cost-effective prevention strategies.

  2. First CLUSTER plasma and magnetic field measurements of flux transfer events in conjunction with their ionospheric flow signatures

    NASA Astrophysics Data System (ADS)

    Rae, I. J.; Taylor, M. G.; Lavraud, B.; Cowley, S. W.; Lester, M.; Fenrich, F. R.; Fazakerley, A.; Räme, H.; Sofko, G.; Balogh, A.

    2001-12-01

    The launch of the Cluster satellite constellation allows, amongst other things, the study of the small-scale spatio-temporal structures in the near-Earth geospace. We present a case study of the high-altitude northern hemispheric cusp by the Cluster-II spacecraft constellation under southward IMF conditions. During this interval Cluster traversed the northern hemispheric dayside region and crossed the magnetopause close to the noon-midnight meridian, and observed both the plasma and magnetic field observations of transient reconnection for a number of hours. Throughout this interval, the ionospheric footprint of the spacecraft maps into the Canadian sector of the Earth's ionosphere into the Saskatoon and Kapuskasing HF radars fields-of-view. This SuperDARN HF radar pair observe the ionospheric flows generated by this transient reconnection during this interval at approximately the same magnetic latitude and local time. The calculated orientation of the reconnected flux tubes is found to be in accordance with the prevailing IMF conditions and the direction of motion of the excited ionospheric flows. We discuss these observations in terms of transient magnetic flux transfer and in terms of the size and location of the active reconnection X-line at the low-latitude magnetopause.

  3. Observation of dynamic equilibrium cluster phase in nanoparticle-polymer system

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kumar, Sugam, E-mail: sugam@barc.gov.in; Mehan, S.; Aswal, V. K.

    2016-05-23

    Small-angle neutron scattering (SANS) and dynamic light scattering (DLS) have been used to investigate the existence of a cluster phase in a nanoparticle-polymer system. The nanoparticle-polymer system shows an interesting reentrant phase behavior where the charge stabilized silica nanoparticles undergo particle clustering and back to individual nanoparticles as a function of polymer concentration. This kind of phase behavior is believed to be directed by opposing attractive and repulsive interactions present in the system. The phase behavior shows two narrow regions of polymer concentration immediately before and after the two-phase formation indicating the possibility of the existence of some equilibrium clusters.more » DLS results show a much higher size of particles than individuals in these two regions which remains unchanged even after dilution. The SANS data show the evolution of attraction with increased volume fraction of the particles supporting the dynamic nature of these clusters.« less

  4. Breast cancer and symptom clusters during radiotherapy.

    PubMed

    Matthews, Ellyn E; Schmiege, Sarah J; Cook, Paul F; Sousa, Karen H

    2012-01-01

    Symptom clusters assessment shifts the clinical focus from a specific symptom to the patient's experience as a whole. Few studies have examined breast cancer symptom clusters during treatment, and fewer studies have addressed symptom clusters during radiation therapy (RT). The theoretical underpinning of this study is the Symptoms Experience Model. Research is needed to identify antecedents and consequences of cancer-related symptom clusters. The present study was intended to determine the clustering of symptoms during RT in women with breast cancer and significant correlations among the symptoms, individual characteristics, and mood. A secondary data analysis from a descriptive correlational study of 93 women at weeks 3 to 7 of RT from centers in the mid-Atlantic region of the United States, Symptom Distress Scale, the subscales of the Positive and Negative Affect Scale, Life Orientation Test, and Self-transcendence Scale were completed. Confirmatory factor analysis revealed symptoms grouped into 3 distinct clusters: pain-insomnia-fatigue, cognitive disturbance-outlook, and gastrointestinal. The pain-insomnia-fatigue and cognitive disturbance-outlook clusters were associated with individual characteristics, optimism, self-transcendence, and positive and negative mood. The gastrointestinal cluster correlated significantly only with positive mood. This study provides insight into symptoms that group together and the relationship of symptom clusters to antecedents and mood. These findings underscore the need to define and standardize the measurement of symptom clusters and understand variability in concurrent symptoms. Attention to symptom clusters shifts the clinical focus from a specific symptom to the patient's experience as a whole and helps identify the most effective interventions.

  5. Massive open star clusters using the VVV survey. II. Discovery of six clusters with Wolf-Rayet stars

    NASA Astrophysics Data System (ADS)

    Chené, A.-N.; Borissova, J.; Bonatto, C.; Majaess, D. J.; Baume, G.; Clarke, J. R. A.; Kurtev, R.; Schnurr, O.; Bouret, J.-C.; Catelan, M.; Emerson, J. P.; Feinstein, C.; Geisler, D.; de Grijs, R.; Hervé, A.; Ivanov, V. D.; Kumar, M. S. N.; Lucas, P.; Mahy, L.; Martins, F.; Mauro, F.; Minniti, D.; Moni Bidin, C.

    2013-01-01

    Context. The ESO Public Survey "VISTA Variables in the Vía Láctea" (VVV) provides deep multi-epoch infrared observations for an unprecedented 562 sq. degrees of the Galactic bulge, and adjacent regions of the disk. Nearly 150 new open clusters and cluster candidates have been discovered in this survey. Aims: This is the second in a series of papers about young, massive open clusters observed using the VVV survey. We present the first study of six recently discovered clusters. These clusters contain at least one newly discovered Wolf-Rayet (WR) star. Methods: Following the methodology presented in the first paper of the series, wide-field, deep JHKs VVV observations, combined with new infrared spectroscopy, are employed to constrain fundamental parameters for a subset of clusters. Results: We find that the six studied stellar groups are real young (2-7 Myr) and massive (between 0.8 and 2.2 × 103 M⊙) clusters. They are highly obscured (AV ~ 5-24 mag) and compact (1-2 pc). In addition to WR stars, two of the six clusters also contain at least one red supergiant star, and one of these two clusters also contains a blue supergiant. We claim the discovery of 8 new WR stars, and 3 stars showing WR-like emission lines which could be classified WR or OIf. Preliminary analysis provides initial masses of ~30-50 M⊙ for the WR stars. Finally, we discuss the spiral structure of the Galaxy using the six new clusters as tracers, together with the previously studied VVV clusters. Based on observations with ISAAC, VLT, ESO (programme 087.D-0341A), New Technology Telescope at ESO's La Silla Observatory (programme 087.D-0490A) and with the Clay telescope at the Las Campanas Observatory (programme CN2011A-086). Also based on data from the VVV survey (programme 172.B-2002).

  6. Searching for galaxy clusters in the Kilo-Degree Survey

    NASA Astrophysics Data System (ADS)

    Radovich, M.; Puddu, E.; Bellagamba, F.; Roncarelli, M.; Moscardini, L.; Bardelli, S.; Grado, A.; Getman, F.; Maturi, M.; Huang, Z.; Napolitano, N.; McFarland, J.; Valentijn, E.; Bilicki, M.

    2017-02-01

    Aims: In this paper, we present the tools used to search for galaxy clusters in the Kilo Degree Survey (KiDS), and our first results. Methods: The cluster detection is based on an implementation of the optimal filtering technique that enables us to identify clusters as over-densities in the distribution of galaxies using their positions on the sky, magnitudes, and photometric redshifts. The contamination and completeness of the cluster catalog are derived using mock catalogs based on the data themselves. The optimal signal to noise threshold for the cluster detection is obtained by randomizing the galaxy positions and selecting the value that produces a contamination of less than 20%. Starting from a subset of clusters detected with high significance at low redshifts, we shift them to higher redshifts to estimate the completeness as a function of redshift: the average completeness is 85%. An estimate of the mass of the clusters is derived using the richness as a proxy. Results: We obtained 1858 candidate clusters with redshift 0 cluster catalogs shows that we match more than 50% of the clusters (77% in the case of the redMaPPer catalog). We also cross-matched our cluster catalog with the Abell clusters, and clusters found by XMM and in the Planck-SZ survey; however, only a small number of them lie inside the KiDS area currently available. The catalog is available at http://kids.strw.leidenuniv.nl/DR2 and at the CDS via anonymous ftp to http://cdsarc.u-strasbg.fr (http://130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/598/A107

  7. Genetic and cellular analysis of cross-incompatibility in Zea mays.

    PubMed

    Lu, Yongxian; Kermicle, Jerry L; Evans, Matthew M S

    2014-03-01

    Three genetic systems conferring cross-incompatibility have been described in Zea mays: Teosinte crossing barrier1-strong (Tcb1-s) found in teosinte, and Gametophyte factor1-strong (Ga1-s) and Ga2-s found in maize and teosinte. The reproductive barrier between maize and some weedy teosintes is controlled by the Tcb1-s locus. Multi-generation inheritance experiments on two independent Tcb1-s lineages show that the Tcb1-s barrier is unstable in some maize lines. Reciprocal crosses between Tcb1-s tester plants and three recombinants in the Tcb1-s mapping region demonstrate that the Tcb1-s haplotype contains separable male and female components. In vivo assays of the dynamics of pollen tube growth and pollen tube morphology during rejection of incompatible pollen in silks carrying the Tcb1-s, Ga1-s, or Ga2-s barriers showed that, in all three, pollen tube growth is slower than in compatible crosses at early stages and had ceased by 24 h after pollination. In all three crossing barrier systems, incompatible pollen tubes have clustered callose plugs in contrast to pollen tubes of compatible crosses. Incompatible pollen tubes growing in the Tcb1-s, Ga1-s, and Ga2-s silks have different morphologies: straight, curved, and kinked, respectively. The distinct morphologies suggest that these crossing barriers block incompatible pollen through different mechanisms. This study lays the foundation for cloning the Tcb1 genes and provides clues about the cellular mechanisms involved in pollen rejection in the Tcb1-s, Ga1-s, and Ga2-s crossing barriers.

  8. Spatial scan statistics for detection of multiple clusters with arbitrary shapes.

    PubMed

    Lin, Pei-Sheng; Kung, Yi-Hung; Clayton, Murray

    2016-12-01

    In applying scan statistics for public health research, it would be valuable to develop a detection method for multiple clusters that accommodates spatial correlation and covariate effects in an integrated model. In this article, we connect the concepts of the likelihood ratio (LR) scan statistic and the quasi-likelihood (QL) scan statistic to provide a series of detection procedures sufficiently flexible to apply to clusters of arbitrary shape. First, we use an independent scan model for detection of clusters and then a variogram tool to examine the existence of spatial correlation and regional variation based on residuals of the independent scan model. When the estimate of regional variation is significantly different from zero, a mixed QL estimating equation is developed to estimate coefficients of geographic clusters and covariates. We use the Benjamini-Hochberg procedure (1995) to find a threshold for p-values to address the multiple testing problem. A quasi-deviance criterion is used to regroup the estimated clusters to find geographic clusters with arbitrary shapes. We conduct simulations to compare the performance of the proposed method with other scan statistics. For illustration, the method is applied to enterovirus data from Taiwan. © 2016, The International Biometric Society.

  9. Distant Cluster Hunting. II; A Comparison of X-Ray and Optical Cluster Detection Techniques and Catalogs from the ROSAT Optical X-Ray Survey

    NASA Technical Reports Server (NTRS)

    Donahue, Megan; Scharf, Caleb A.; Mack, Jennifer; Lee, Y. Paul; Postman, Marc; Rosait, Piero; Dickinson, Mark; Voit, G. Mark; Stocke, John T.

    2002-01-01

    We present and analyze the optical and X-ray catalogs of moderate-redshift cluster candidates from the ROSA TOptical X-Ray Survey, or ROXS. The survey covers the sky area contained in the fields of view of 23 deep archival ROSA T PSPC pointings, 4.8 square degrees. The cross-correlated cluster catalogs were con- structed by comparing two independent catalogs extracted from the optical and X-ray bandpasses, using a matched-filter technique for the optical data and a wavelet technique for the X-ray data. We cross-identified cluster candidates in each catalog. As reported in Paper 1, the matched-filter technique found optical counter- parts for at least 60% (26 out of 43) of the X-ray cluster candidates; the estimated redshifts from the matched filter algorithm agree with at least 7 of 1 1 spectroscopic confirmations (Az 5 0.10). The matched filter technique. with an imaging sensitivity of ml N 23, identified approximately 3 times the number of candidates (155 candidates, 142 with a detection confidence >3 u) found in the X-ray survey of nearly the same area. There are 57 X-ray candidates, 43 of which are unobscured by scattered light or bright stars in the optical images. Twenty-six of these have fairly secure optical counterparts. We find that the matched filter algorithm, when applied to images with galaxy flux sensitivities of mI N 23, is fairly well-matched to discovering z 5 1 clusters detected by wavelets in ROSAT PSPC exposures of 8000-60,000 s. The difference in the spurious fractions between the optical and X-ray (30%) and IO%, respectively) cannot account for the difference in source number. In Paper I, we compared the optical and X-ray cluster luminosity functions and we found that the luminosity functions are consistent if the relationship between X-ray and optical luminosities is steep (Lx o( L&f). Here, in Paper 11, we present the cluster catalogs and a numerical simulation of the ROXS. We also present color-magnitude plots for several of the cluster

  10. Breakup of a homeobox cluster after genome duplication in teleosts

    PubMed Central

    Mulley, John F.; Chiu, Chi-hua; Holland, Peter W. H.

    2006-01-01

    Several families of homeobox genes are arranged in genomic clusters in metazoan genomes, including the Hox, ParaHox, NK, Rhox, and Iroquois gene clusters. The selective pressures responsible for maintenance of these gene clusters are poorly understood. The ParaHox gene cluster is evolutionarily conserved between amphioxus and human but is fragmented in teleost fishes. We show that two basal ray-finned fish, Polypterus and Amia, each possess an intact ParaHox cluster; this implies that the selective pressure maintaining clustering was lost after whole-genome duplication in teleosts. Cluster breakup is because of gene loss, not transposition or inversion, and the total number of ParaHox genes is the same in teleosts, human, mouse, and frog. We propose that this homeobox gene cluster is held together in chordates by the existence of interdigitated control regions that could be separated after locus duplication in the teleost fish. PMID:16801555

  11. The Herschel Virgo Cluster Survey - XVI. A cluster inventory

    NASA Astrophysics Data System (ADS)

    Davies, J. I.; Bianchi, S.; Baes, M.; Bendo, G. J.; Clemens, M.; De Looze, I.; di Serego Alighieri, S.; Fritz, J.; Fuller, C.; Pappalardo, C.; Hughes, T. M.; Madden, S.; Smith, M. W. L.; Verstappen, J.; Vlahakis, C.

    2014-03-01

    Herschel far-infrared (FIR) observations are used to construct Virgo cluster galaxy luminosity functions and to show that the cluster lacks the very bright and the numerous faint sources detected in field galaxy surveys. The FIR spectral energy distributions are fitted to obtain dust masses and temperatures and the dust mass function. The cluster is overdense in dust by about a factor of 100 compared to the field. The same emissivity (β)-temperature relation applies for different galaxies as that found for different regions of M31. We use optical and H I data to show that Virgo is overdense in stars and atomic gas by about a factor of 100 and 20, respectively. Metallicity values are used to measure the mass of metals in the gas phase. The mean metallicity is ˜0.7 solar, and ˜50 per cent of the metals are in the dust. For the cluster as a whole, the mass density of stars in galaxies is eight times that of the gas and the gas mass density is 130 times that of the metals. We use our data to consider the chemical evolution of the individual galaxies, inferring that the measured variations in the effective yield are due to galaxies having different ages, being affected to varying degrees by gas loss. Four galaxy scaling relations are considered: mass-metallicity, mass-velocity, mass-star formation rate and mass-radius - we suggest that initial galaxy mass is the prime driver of a galaxy's ultimate destiny. Finally, we use X-ray observations and galaxy dynamics to assess the dark and baryonic matter content compared to the cosmological model.

  12. Fully convolutional network with cluster for semantic segmentation

    NASA Astrophysics Data System (ADS)

    Ma, Xiao; Chen, Zhongbi; Zhang, Jianlin

    2018-04-01

    At present, image semantic segmentation technology has been an active research topic for scientists in the field of computer vision and artificial intelligence. Especially, the extensive research of deep neural network in image recognition greatly promotes the development of semantic segmentation. This paper puts forward a method based on fully convolutional network, by cluster algorithm k-means. The cluster algorithm using the image's low-level features and initializing the cluster centers by the super-pixel segmentation is proposed to correct the set of points with low reliability, which are mistakenly classified in great probability, by the set of points with high reliability in each clustering regions. This method refines the segmentation of the target contour and improves the accuracy of the image segmentation.

  13. Two-photon absorption cross sections within equation-of-motion coupled-cluster formalism using resolution-of-the-identity and Cholesky decomposition representations: Theory, implementation, and benchmarks

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Nanda, Kaushik D.; Krylov, Anna I.

    The equation-of-motion coupled-cluster (EOM-CC) methods provide a robust description of electronically excited states and their properties. Here, we present a formalism for two-photon absorption (2PA) cross sections for the equation-of-motion for excitation energies CC with single and double substitutions (EOM-CC for electronically excited states with single and double substitutions) wave functions. Rather than the response theory formulation, we employ the expectation-value approach which is commonly used within EOM-CC, configuration interaction, and algebraic diagrammatic construction frameworks. In addition to canonical implementation, we also exploit resolution-of-the-identity (RI) and Cholesky decomposition (CD) for the electron-repulsion integrals to reduce memory requirements and to increasemore » parallel efficiency. The new methods are benchmarked against the CCSD and CC3 response theories for several small molecules. We found that the expectation-value 2PA cross sections are within 5% from the quadratic response CCSD values. The RI and CD approximations lead to small errors relative to the canonical implementation (less than 4%) while affording computational savings. RI/CD successfully address the well-known issue of large basis set requirements for 2PA cross sections calculations. The capabilities of the new code are illustrated by calculations of the 2PA cross sections for model chromophores of the photoactive yellow and green fluorescent proteins.« less

  14. Clustering by neurocognition for fine-mapping of the schizophrenia susceptibility loci on chromosome 6p

    PubMed Central

    Lin, Sheng-Hsiang; Liu, Chih-Min; Liu, Yu-Li; Fann, Cathy Shen-Jang; Hsiao, Po-Chang; Wu, Jer-Yuarn; Hung, Shuen-Iu; Chen, Chun-Houh; Wu, Han-Ming; Jou, Yuh-Shan; Liu, Shi K.; Hwang, Tzung J.; Hsieh, Ming H.; Chang, Chien-Ching; Yang, Wei-Chih; Lin, Jin-Jia; Chou, Frank Huang-Chih; Faraone, Stephen V.; Tsuang, Ming T.; Hwu, Hai-Gwo; Chen, Wei J.

    2009-01-01

    Chromosome 6p is one of the most commonly implicated regions in the genome-wide linkage scans of schizophrenia, whereas further association studies for markers in this region were inconsistent likely due to heterogeneity. This study aimed to identify more homogeneous subgroups of families for fine mapping on regions around markers D6S296 and D6S309 (both in 6p24.3) as well as D6S274 (in 6p22.3) by means of similarity in neurocognitive functioning. A total of 160 families of patients with schizophrenia comprising at least two affected siblings who had data for 8 neurocognitive test variables of the Continuous Performance Test (CPT) and the Wisconsin Card Sorting Test (WCST) were subjected to cluster analysis with data visualization using the test scores of both affected siblings. Family clusters derived were then used separately in family-based association tests for 64 single nucleotide polymorphisms covering the region of 6p24.3 and 6p22.3. Three clusters were derived from the family-based clustering, with deficit cluster 1 representing deficit on the CPT, deficit cluster 2 representing deficit on both the CPT and the WCST, and a third cluster of non-deficit. After adjustment using false discovery rate for multiple testing, SNP rs13873 and haplotype rs1225934-rs13873 on BMP6-TXNDC5 genes were significantly associated with schizophrenia for the deficit cluster 1 but not for the deficit cluster 2 or non-deficit cluster. Our results provide further evidence that the BMP6-TXNDC5 locus on 6p24.3 may play a role in the selective impairments on sustained attention of schizophrenia. PMID:19694819

  15. Minimum package for cross-border TB control and care in the WHO European region: a Wolfheze consensus statement

    PubMed Central

    Dara, Masoud; de Colombani, Pierpaolo; Petrova-Benedict, Roumyana; Centis, Rosella; Zellweger, Jean-Pierre; Sandgren, Andreas; Heldal, Einar; Sotgiu, Giovanni; Jansen, Niesje; Bahtijarevic, Rankica; Migliori, Giovanni Battista

    2012-01-01

    The World Health Organization (WHO) European region estimates that more than 400,000 tuberculosis (TB) cases occur in Europe, a large proportion of them among migrants. A coordinated public health mechanism to guarantee TB prevention, diagnosis, treatment and care across borders is not in place. A consensus paper describing the minimum package of cross-border TB control and care was prepared by a task force following a literature review, and with input from the national TB control programme managers of the WHO European region and the Wolfheze 2011 conference. A literature review focused on the subject of TB in migrants was carried out, selecting documents published during the 11-yr period 2001–2011. Several issues were identified in cross-border TB control and care, varying from the limited access to early TB diagnosis, to the lack of continuity of care and information during migration, and the availability of, and access to, health services in the new country. The recommended minimum package addresses the current shortcomings and intends to improve the situation by covering several areas: political commitment (including the implementation of a legal framework for TB cross-border collaboration), financial mechanisms and adequate health service delivery (prevention, infection control, contact management, diagnosis and treatment, and psychosocial support). PMID:22653772

  16. New VVV Survey Globular Cluster Candidates in the Milky Way Bulge

    NASA Astrophysics Data System (ADS)

    Minniti, Dante; Geisler, Douglas; Alonso-García, Javier; Palma, Tali; Beamín, Juan Carlos; Borissova, Jura; Catelan, Marcio; Clariá, Juan J.; Cohen, Roger E.; Contreras Ramos, Rodrigo; Dias, Bruno; Fernández-Trincado, Jose G.; Gómez, Matías; Hempel, Maren; Ivanov, Valentin D.; Kurtev, Radostin; Lucas, Phillip W.; Moni-Bidin, Christian; Pullen, Joyce; Ramírez Alegría, Sebastian; Saito, Roberto K.; Valenti, Elena

    2017-11-01

    It is likely that a number of Galactic globular clusters remain to be discovered, especially toward the Galactic bulge. High stellar density combined with high and differential interstellar reddening are the two major problems for finding globular clusters located toward the bulge. We use the deep near-IR photometry of the VISTA Variables in the Vía Láctea (VVV) Survey to search for globular clusters projected toward the Galactic bulge, and hereby report the discovery of 22 new candidate globular clusters. These objects, detected as high density regions in our maps of bulge red giants, are confirmed as globular cluster candidates by their color-magnitude diagrams. We provide their coordinates as well as their near-IR color-magnitude diagrams, from which some basic parameters are derived, such as reddenings and heliocentric distances. The color-magnitude diagrams reveal well defined red giant branches in all cases, often including a prominent red clump. The new globular cluster candidates exhibit a variety of extinctions (0.06 < A Ks < 2.77) and distances (5.3 < D < 9.5 kpc). We also classify the globular cluster candidates into 10 metal-poor and 12 metal-rich clusters, based on the comparison of their color-magnitude diagrams with those of known globular clusters also observed by the VVV Survey. Finally, we argue that the census for Galactic globular clusters still remains incomplete, and that many more candidate globular clusters (particularly the low luminosity ones) await to be found and studied in detail in the central regions of the Milky Way. Based on observations taken within the ESO programs 179.B-2002 and 298.D-5048.

  17. Consensus of satellite cluster flight using an energy-matching optimal control method

    NASA Astrophysics Data System (ADS)

    Luo, Jianjun; Zhou, Liang; Zhang, Bo

    2017-11-01

    This paper presents an optimal control method for consensus of satellite cluster flight under a kind of energy matching condition. Firstly, the relation between energy matching and satellite periodically bounded relative motion is analyzed, and the satellite energy matching principle is applied to configure the initial conditions. Then, period-delayed errors are adopted as state variables to establish the period-delayed errors dynamics models of a single satellite and the cluster. Next a novel satellite cluster feedback control protocol with coupling gain is designed, so that the satellite cluster periodically bounded relative motion consensus problem (period-delayed errors state consensus problem) is transformed to the stability of a set of matrices with the same low dimension. Based on the consensus region theory in the research of multi-agent system consensus issues, the coupling gain can be obtained to satisfy the requirement of consensus region and decouple the satellite cluster information topology and the feedback control gain matrix, which can be determined by Linear quadratic regulator (LQR) optimal method. This method can realize the consensus of satellite cluster period-delayed errors, leading to the consistency of semi-major axes (SMA) and the energy-matching of satellite cluster. Then satellites can emerge the global coordinative cluster behavior. Finally the feasibility and effectiveness of the present energy-matching optimal consensus for satellite cluster flight is verified through numerical simulations.

  18. Clustering of health-related behaviors among early and mid-adolescents in Tuscany: results from a representative cross-sectional study.

    PubMed

    Lazzeri, Giacomo; Panatto, Donatella; Domnich, Alexander; Arata, Lucia; Pammolli, Andrea; Simi, Rita; Giacchi, Mariano Vincenzo; Amicizia, Daniela; Gasparini, Roberto

    2018-03-01

    A huge amount of literature suggests that adolescents' health-related behaviors tend to occur in clusters, and the understanding of such behavioral clustering may have direct implications for the effective tailoring of health-promotion interventions. Despite the usefulness of analyzing clustering, Italian data on this topic are scant. This study aimed to evaluate the clustering patterns of health-related behaviors. The present study is based on data from the Health Behaviors in School-aged Children (HBSC) study conducted in Tuscany in 2010, which involved 3291 11-, 13- and 15-year olds. To aggregate students' data on 22 health-related behaviors, factor analysis and subsequent cluster analysis were performed. Factor analysis revealed eight factors, which were dubbed in accordance with their main traits: 'Alcohol drinking', 'Smoking', 'Physical activity', 'Screen time', 'Signs & symptoms', 'Healthy eating', 'Violence' and 'Sweet tooth'. These factors explained 67% of variance and underwent cluster analysis. A six-cluster κ-means solution was established with a 93.8% level of classification validity. The between-cluster differences in both mean age and gender distribution were highly statistically significant. Health-compromising behaviors are common among Tuscan teens and occur in distinct clusters. These results may be used by schools, health-promotion authorities and other stakeholders to design and implement tailored preventive interventions in Tuscany.

  19. Cross-genera transferability of rice and finger millet genomic SSRs to barnyard millet (Echinochloa spp.).

    PubMed

    Kalyana Babu, B; Sood, Salej; Kumar, Dinesh; Joshi, Anjeli; Pattanayak, A; Kant, Lakshmi; Upadhyaya, H D

    2018-02-01

    Barnyard millet ( Echinochloa spp.) is an important crop from nutritional point of view, nevertheless, the genetic information is very scarce. In the present investigation, rice and finger millet genomic SSRs were used for assessing cross transferability, identification of polymorphic markers, syntenic regions, genetic diversity and population structure analysis of barnyard millet genotypes. We observed 100% cross transferability for finger millet SSRs, of which 91% were polymorphic, while 71% of rice markers were cross transferable with 48% polymorphic out of them. Twenty-nine and sixteen highly polymorphic finger millet and rice SSRs yielded a mean of 4.3 and 3.38 alleles per locus in barnyard millet genotypes, respectively. The PIC values varied from 0.27 to 0.73 at an average of 0.54 for finger millet SSRs, whereas it was from 0.15 to 0.67 at an average of 0.44 for rice SSRs. High synteny was observed for markers related to panicle length, yield-related traits, spikelet fertility, plant height, root traits, leaf senescence, blast and brown plant hopper resistance. Although the rice SSRs located on chromosome 10 followed by chromosome 6 and 11 were found to be more transferable to barnyard millet, the finger millet SSRs were more polymorphic and transferable to barnyard millet genotypes. These SSR data of finger millet and rice individually as well as combined together grouped the 11 barnyard millet genotypes into 2 major clusters. The results of population structure analysis were similar to cluster analysis.

  20. A youthful cluster

    NASA Image and Video Library

    2015-08-24

    Shown here in a new image taken with the Advanced Camera for Surveys (ACS) on board the NASA/ESA Hubble Space Telescope, is the globular cluster NGC 1783. This is one of the biggest globular clusters in the Large Magellanic Cloud, a satellite galaxy of our own galaxy, the Milky Way, in the southern hemisphere constellation of Dorado. First observed by John Herschel in 1835, NGC 1783 is nearly 160 000 light-years from Earth, and has a mass around 170 000 times that of the Sun. Globular clusters are dense collections of stars held together by their own gravity, which orbit around galaxies like satellites. The image clearly shows the symmetrical shape of NGC 1783 and the concentration of stars towards the centre, both typical features of globular clusters. By measuring the colour and brightness of individual stars, astronomers can deduce an overall age for a cluster and a picture of its star formation history. NGC 1783 is thought to be under one and a half billion years old — which is very young for globular clusters, which are typically several billion years old. During that time, it is thought to have undergone at least two periods of star formation, separated by 50 to 100 million years. This ebb and flow of star-forming activity is an indicator of how much gas is available for star formation at any one time. When the most massive stars created in the first burst of formation explode as supernovae they blow away the gas needed to form further stars, but the gas reservoir can later be replenished by less massive stars which last longer and shed their gas less violently. After this gas flows to the dense central regions of the star cluster, a second phase of star formation can take place and once again the short-lived massive stars blow away any leftover gas. This cycle can continue a few times, at which time the remaining gas reservoir is thought to be too small to form any new stars. A version of this image was entered into the Hubble's Hidden Treasures image pr