ERIC Educational Resources Information Center
Yates, Steven Lowell
2009-01-01
This research study was an investigation of current faculty development practices for alternative delivery systems. Attention was given to faculty development in general as well as specific facets of faculty development for alternative delivery systems. Future or intended faculty development practices were pursued, along with factors that…
ERIC Educational Resources Information Center
Showanasai, Parinya; Lu, Jiafang; Hallinger, Philip
2013-01-01
Purpose: The extant literature on school leadership development is dominated by conceptual analysis, descriptive studies of current practice, critiques of current practice, and prescriptions for better ways to approach practice. Relatively few studies have examined impact of leadership development using experimental methods, among which even fewer…
Current Bypassing Properties by Thermal Switch for PCS Application on NMR/MRI HTS Magnets
NASA Astrophysics Data System (ADS)
Kim, S. B.; Takahashi, M.; Saito, R.; Park, Y. J.; Lee, M. W.; Oh, Y. K.; Ann, H. S.
We develop the compact NMR/MRI device using high temperature superconducting (HTS) wires with the persistent current mode operating. So, the joint techniques between 2G wires are very important issue and many studies have been carried out. Recently, the Kbigdot JOINS, Inc. has developed successfully the high performance superconducting joints between 2G wires by partial melting diffusion and oxygenation annealing process [1]. In this study, the current bypassing properties in a loop-shaped 2G wire are measured experimentally to develop the permanent current switch (PSC). The current bypassing properties of loop-shaped test coil wound with 2G wire (GdBCO) are evaluated by measured the self-magnetic field due to bypassed current by Hall sensors. The strain gauge was used as heater for persistent current switch, and thermal properties against various thermal inputs were investigated experimentally.
ERIC Educational Resources Information Center
Umana-Taylor, Adriana J.; Updegraff, Kimberly A.; White, Rebecca M. B.; Herzog, Melissa J.; Pflieger, Jacqueline C.; Madden-Derdich, Debra
2011-01-01
The current study describes the development and psychometric testing of the Global Support From Mother Figure During Pregnancy Scale (GSMF-P). The measure is developed in both Spanish and English to assess social support provided to adolescents during their pregnancies. The current study examines the reliability, cross-language equivalence, and…
The development of neural correlates for memory formation
Ofen, Noa
2012-01-01
A growing body of literature considers the development of episodic memory systems in the brain; the majority are neuroimaging studies conducted during memory encoding in order to explore developmental trajectories in memory formation. This review considers evidence from behavioral studies of memory development, neural correlates of memory formation in adults, and structural brain development, all of which form the foundation of a developmental cognitive neuroscience approach to memory development. I then aim to integrate the current evidence from developmental functional neuroimaging studies of memory formation with respect to three hypotheses. First, memory development reflects the development in the use of memory strategies, linked to prefrontal cortex. Second, developmental effects within the medial temporal lobes are more complex, and correspond to current notions about the nature in which the MTL support the formation of memory. Third, neurocognitive changes in content representation influence memory. Open issues and current directions are discussed. PMID:22414608
ERIC Educational Resources Information Center
Jutasong, Chanokpon; Sirisuthi, Chaiyut; Phusri-on, Songsak
2016-01-01
The objectives of this research are: 1) to study factors and indicators, 2) to study current situations, desirable situations and techniques, 3) to develop the Program, and 4) to study the effect of Program. It comprised 4 phases: (1) studying the factors and indicators; (2) studying the current situations, desirable situations and techniques; (3)…
Nakamura, Hideaki
2018-05-08
In Part I of the present review series, I presented the current state of the water environment by focusing on Japanese cases and discussed the need to further develop microbial biosensor technologies for the actual water environment. I comprehensively present trends after approximately 2010 in microbial biosensor development for the water environment. In the first section, after briefly summarizing historical studies, recent studies on microbial biosensor principles are introduced. In the second section, recent application studies for the water environment are also introduced. Finally, I conclude the present review series by describing the need to further develop microbial biosensor technologies. Graphical abstract Current water pollution indirectly occurs by anthropogenic eutrophication (Part I). Recent trends in microbial biosensor development for water environment are described in part II of the present review series.
NASA Astrophysics Data System (ADS)
Hussain, Azham; Mkpojiogu, Emmanuel O. C.; Abdullah, Inam
2016-08-01
Requirements Engineering (RE) is a systemic and integrated process of eliciting, elaborating, negotiating, validating and managing of the requirements of a system in a software development project. UUM has been supported by various systems developed and maintained by the UUM Information Technology (UUMIT) Centre. The aim of this study was to assess the current requirements engineering practices at UUMIT. The main problem that prompted this research is the lack of studies that support software development activities at the UUMIT. The study is geared at helping UUMIT produce quality but time and cost saving software products by implementing cutting edge and state of the art requirements engineering practices. Also, the study contributes to UUM by identifying the activities needed for software development so that the management will be able to allocate budget to provide adequate and precise training for the software developers. Three variables were investigated: Requirement Description, Requirements Development (comprising: Requirements Elicitation, Requirements Analysis and Negotiation, Requirements Validation), and Requirement Management. The results from the study showed that the current practice of requirement engineering in UUMIT is encouraging, but still need further development and improvement because a few RE practices were seldom practiced.
ERIC Educational Resources Information Center
Kjellström, Sofia; Golino, Hudson; Hamer, Rebecca; Van Rossum, Erik Jan; Almers, Ellen
2016-01-01
Qualitative research supports a developmental dimension in views on teaching and learning, but there are currently no quantitative tools to measure the full range of this development. To address this, we developed the Epistemological Development in Teaching and Learning Questionnaire (EDTLQ). In the current study the psychometric properties of the…
ERIC Educational Resources Information Center
Subitha, G. V.
2018-01-01
Located within the context of Indian education reforms, this study is a critique of the current model of continuous professional development of teachers. The study, by reviewing national policy documents and research literature, argues that there is a need to re-conceptualize and re-define the current model of professional development of teachers.…
ERIC Educational Resources Information Center
Haisheng, Pan; Shibin, Wang; Deyi, Long
2016-01-01
Strengthening school-enterprise development is currently a major theme in the development of higher vocational education. The results of our survey study show that school-enterprise cooperation in Chinese higher vocational education is currently characterized by disparities in the interests of different entities, low quality of cooperation, and…
ERIC Educational Resources Information Center
Ulubey, Özgür; Yildirim, Kasim; Alpaslan, Muhammet Mustafa; Aykaç, Necdet
2017-01-01
The purpose of the current study is to determine teachers' opinions about professional development schools. In the current study; one of the mixed methods, the convergent design was employed. The sampling of the quantitative dimension of the study is comprised of 256 teachers working in 21 elementary and secondary schools in the city of Mugla. The…
An Incubatable Direct Current Stimulation System for In Vitro Studies of Mammalian Cells
Panitch, Alyssa; Caplan, Michael; Sweeney, James D.
2012-01-01
Abstract The purpose of this study was to provide a simplified alternative technology and format for direct current stimulation of mammalian cells. An incubatable reusable stimulator was developed that effectively delivers a regulated current and does not require constant monitoring. PMID:23514694
Ultra high vacuum test setup for electron gun
NASA Astrophysics Data System (ADS)
Pandiyar, M. L.; Prasad, M.; Jain, S. K.; Kumar, R.; Hannurkar, P. R.
2008-05-01
Ultra High Vacuum (UHV) test setup for electron gun testing has been developed. The development of next generation light sources and accelerators require development of klystron as a radio frequency power source, and in turn electron gun. This UHV electron gun test setup can be used to test the electron guns ranging from high average current, quasi-continuous wave to high peak current, single pulse etc. An electron gun has been designed, fabricated, assembled and tested for insulation up to 80 kV under the programme to develop high power klystron for future accelerators. Further testing includes the electron emission parameters characterization of the cathode, as it determines the development of a reliable and efficient electron gun with high electron emission current and high life time as well. This needs a clean ultra high vacuum to study these parameters particularly at high emission current. The cathode emission current, work function and vapour pressure of cathode surface material at high temperature studies will further help in design and development of high power electron gun The UHV electron gun test setup consists of Turbo Molecular Pump (TMP), Sputter Ion Pump (SIP), pressure gauge, high voltage and cathode power supplies, current measurement device, solenoid magnet and its power supply, residual gas analyser etc. The ultimate vacuum less than 2×10-9 mbar was achieved. This paper describes the UHV test setup for electron gun testing.
Perspectives on setting limits for RF contact currents: a commentary.
Tell, Richard A; Tell, Christopher A
2018-01-15
Limits for exposure to radiofrequency (RF) contact currents are specified in the two dominant RF safety standards and guidelines developed by the Institute of Electrical and Electronics Engineers (IEEE) and the International Commission on Non-Ionizing Radiation Protection (ICNIRP). These limits are intended to prevent RF burns when contacting RF energized objects caused by high local tissue current densities. We explain what contact currents are and review some history of the relevant limits with an emphasis on so-called "touch" contacts, i.e., contact between a person and a contact current source during touch via a very small contact area. Contact current limits were originally set on the basis of controlling the specific absorption rate resulting from the current flowing through regions of small conductive cross section within the body, such as the wrist or ankle. More recently, contact currents have been based on thresholds of perceived heating. In the latest standard from the IEEE developed for NATO, contact currents have been based on two research studies in which thresholds for perception of thermal warmth or thermal pain have been measured. Importantly, these studies maximized conductive contact between the subject and the contact current source. This factor was found to dominate the response to heating wherein high resistance contact, such as from dry skin, can result in local heating many times that from a highly conductive contact. Other factors such as electrode size and shape, frequency of the current and the physical force associated with contact are found to introduce uncertainty in threshold values when comparing data across multiple studies. Relying on studies in which the contact current is minimized for a given threshold does not result in conservative protection limits. Future efforts to develop limits on contact currents should include consideration of (1) the basis for the limits (perception, pain, tissue damage); (2) understanding of the practical conditions of real world exposure for contact currents such as contact resistance, size and shape of the contact electrode and applied force at the point of contact; (3) consistency of how contact currents are applied in research studies across different researchers; (4) effects of frequency.
ERIC Educational Resources Information Center
Schultheiss, Donna E. Palladino
2008-01-01
This article reviews the current status and a future agenda for childhood career development theory, research, and practice. The fragmented nature of the current state of the literature is noted, and a call is made for a reexamination and reconsideration of the childhood developmental pathways of life's work. It is suggested that the study of…
Research on resistance characteristics of YBCO tape under short-time DC large current impact
NASA Astrophysics Data System (ADS)
Zhang, Zhifeng; Yang, Jiabin; Qiu, Qingquan; Zhang, Guomin; Lin, Liangzhen
2017-06-01
Research of the resistance characteristics of YBCO tape under short-time DC large current impact is the foundation of the developing DC superconducting fault current limiter (SFCL) for voltage source converter-based high voltage direct current system (VSC-HVDC), which is one of the valid approaches to solve the problems of renewable energy integration. SFCL can limit DC short-circuit and enhance the interrupting capabilities of DC circuit breakers. In this paper, under short-time DC large current impacts, the resistance features of naked tape of YBCO tape are studied to find the resistance - temperature change rule and the maximum impact current. The influence of insulation for the resistance - temperature characteristics of YBCO tape is studied by comparison tests with naked tape and insulating tape in 77 K. The influence of operating temperature on the tape is also studied under subcooled liquid nitrogen condition. For the current impact security of YBCO tape, the critical current degradation and top temperature are analyzed and worked as judgment standards. The testing results is helpful for in developing SFCL in VSC-HVDC.
Northeast Tennessee Educators' Perception of STEM Education Implementation
ERIC Educational Resources Information Center
Turner, Kristin Beard
2013-01-01
A quantitative nonexperimental survey study was developed to investigate Northeast Tennessee K-8 educators' perceptions of STEM education. This study was an examination of current perceptions of STEM education. Perceived need, current implementation practices, access to STEM resources, definition of STEM, and the current condition of STEM in…
ERIC Educational Resources Information Center
Pradabpech, Pipat; Chantarasombat, Chalard; Sriampai, Anan
2015-01-01
This research for: 1) to study the current situation and problem in KM, 2) to develop the KM Model, and 3) to evaluate the finding usage of the KM Model for developing the Internal Quality Assurance of Educational Opportunity Expansion Schools. There were 3 Phases of research implementation. Phase 1: the current situation and problem in KM, was…
CURRENT PRACTICES IN QSAR DEVELOPMENT AND APPLICATIONS
Current Practices in QSAR Development and Applications
Although it is commonly assumed that the structure and properties of a single chemical determines its activity in a particular biological system, it is only through study of how biological activity varies with changes...
Social Work Education. Coombe Lodge Report, Study Conference 74/208.
ERIC Educational Resources Information Center
Further Education Staff Coll., Blagdon (England).
Papers presented on social work education in Britain include: Current developments in social work education (P.H. Young); selection of students (M. Elizabeth Edwards); the management of curriculum development (J. Snelling); the management of a social work department (M.J. McAllister); current issues and developments in social work training (D.C.G.…
Ocean dynamics studies. [of current-wave interactions
NASA Technical Reports Server (NTRS)
1974-01-01
Both the theoretical and experimental investigations into current-wave interactions are discussed. The following three problems were studied: (1) the dispersive relation of a random gravity-capillary wave field; (2) the changes of the statistical properties of surface waves under the influence of currents; and (3) the interaction of capillary-gravity with the nonuniform currents. Wave current interaction was measured and the feasibility of using such measurements for remote sensing of surface currents was considered. A laser probe was developed to measure the surface statistics, and the possibility of using current-wave interaction as a means of current measurement was demonstrated.
NASA Technical Reports Server (NTRS)
Pettit, C. D.; Barkhoudarian, S.; Daumann, A. G., Jr.; Provan, G. M.; ElFattah, Y. M.; Glover, D. E.
1999-01-01
In this study, we proposed an Advanced Health Management System (AHMS) functional architecture and conducted a technology assessment for liquid propellant rocket engine lifecycle health management. The purpose of the AHMS is to improve reusable rocket engine safety and to reduce between-flight maintenance. During the study, past and current reusable rocket engine health management-related projects were reviewed, data structures and health management processes of current rocket engine programs were assessed, and in-depth interviews with rocket engine lifecycle and system experts were conducted. A generic AHMS functional architecture, with primary focus on real-time health monitoring, was developed. Fourteen categories of technology tasks and development needs for implementation of the AHMS were identified, based on the functional architecture and our assessment of current rocket engine programs. Five key technology areas were recommended for immediate development, which (1) would provide immediate benefits to current engine programs, and (2) could be implemented with minimal impact on the current Space Shuttle Main Engine (SSME) and Reusable Launch Vehicle (RLV) engine controllers.
Developmental Neurotoxicology: History and Outline of ...
The present work provides a brief review of basic concepts in developmental neurotoxicology, as well as current representative testing guidelines for evaluating developmental neurotoxicity (DNT) of xenobiotics. Historically, DNT was initially recognized as a “functional” teratogenicity: the main concern was that prenatal and/or early postnatal exposures to chemicals during critical periods of central nervous system (CNS) development would cause later functional abnormalities of the brain. Current internationally harmonized DNT study guidelines are thus intended to predict adverse effects of test compounds on the developing CNS by observing such postnatal parameters as motor activity, startle response, and learning and memory, as well as neropathological alterations. The reliability of current DNT study guidelines and sensitivity of testing methodologies recommended in these guidelines have been confirmed by retrospective evaluations of the many international and domestic collaborative validation studies in developed nations including Japan. Invited review with brief review of basic concepts in developmental neurotoxicology, as well as current representative testing guidelines for evaluating developmental neurotoxicity (DNT) of xenobiotics.
ERIC Educational Resources Information Center
Salem, Ashraf Atta M. S.
2013-01-01
The current study investigates the impact of multiple intelligences-based Instruction on developing speaking skills of the pre-service teachers of English. Therefore, the problem of the current study can be stated in the lack of speaking skills of the pre-service teachers of English in Hurgada faculty of Education, South Valley University. To…
NASA Technical Reports Server (NTRS)
Iijima, T.; Kim, J. S.; Sugiura, M.
1984-01-01
The development of the polar cap current and the relationship of that development to the evolution of auroral electrojets during individual polar geomagnetic disturbances is studied using 1 min average data from US-Canada IMS network stations and standard magnetograms from sites on the polar cap and in the auroral zone. It is found that even when the auroral electrojet activity is weak, polar cap currents producing fields of magnitude approximately 100-200 nT almost always exist. A normal convection current system exists quasi-persistently in the polar cap during extended quiet or weakly disturbed periods of auroral electrojet activity. After one such period, some drastic changes occur in the polar cap currents, which are followed by phases of growth, expansion, and recovery. Polar cap currents cannot all be completely ascribed to a single source mechanism.
Zhao, Fei-Ya; Tao, Ai-En; Xia, Cong-Long
2018-01-01
Paris is a commonly used traditional Chinese medicine (TCM), and has antitumor, antibacterial, sedative, analgesic and hemostatic effects. It has been used as an ingredient of 81 Chinese patent medicines, with a wide application and large market demand. Based on the data retrieved from state Intellectual Property Office patent database, a comprehensive analysis was made on Paris patents, so as to explore the current features of Paris patents in the aspects of domestic patent output, development trend, technology field distribution, time dimension, technology growth rate and patent applicant, and reveal the development trend of China's Paris industry. In addition, based on the current Paris resource application and development, a sustainable, multi-channel and multi-level industrial development approach was built. According to the results, studies of Paris in China are at the rapid development period, with a good development trend. However, because wild Paris resources tend to be exhausted, the studies for artificial cultivation technology should be strengthened to promote the industrial development. Copyright© by the Chinese Pharmaceutical Association.
INEL BNCT Research Program, March/April 1992
DOE Office of Scientific and Technical Information (OSTI.GOV)
Venhuizen, J.R.
1992-09-01
This report presents summaries for two months of current research for the Idaho National Engineering Laboratory (INEL) Boron Neutron Capture Therapy (BNCT) Program. Information is presented on development and murino screening experiments of low-density lipoprotein, carboranyl alanine, and liposome boron containing compounds. Pituitary tumor call culture studies are described. Drug stability, pharmacology and toxicity evaluation of borocaptate sodium (BSH) and boronopheoylalanine (BPA) are described. Treatment protocol development via the large animal (canine) model studies and physiological response evaluation in rats are discussed. Supporting technology development and technical support activities for boron drug biochemistry and purity, analytical and measurement dosimetry, andmore » noninvasive boron quantification activities are included for the current time period. Current publications for the two months are listed.« less
Marine current energy conversion: the dawn of a new era in electricity production.
Bahaj, AbuBakr S
2013-02-28
Marine currents can carry large amounts of energy, largely driven by the tides, which are a consequence of the gravitational effects of the planetary motion of the Earth, the Moon and the Sun. Augmented flow velocities can be found where the underwater topography (bathymetry) in straits between islands and the mainland or in shallows around headlands plays a major role in enhancing the flow velocities, resulting in appreciable kinetic energy. At some of these sites where practical flows are more than 1 m s(-1), marine current energy conversion is considered to be economically viable. This study describes the salient issues related to the exploitation of marine currents for electricity production, resource assessment, the conversion technologies and the status of leading projects in the field. This study also summarizes important issues related to site development and some of the approaches currently being undertaken to inform device and array development. This study concludes that, given the highlighted commitments to establish favourable regulatory and incentive regimes as well as the aspiration for energy independence and combating climate change, the progress to multi-megawatt arrays will be much faster than that achieved for wind energy development.
Engineering design of a high-temperature superconductor current lead
NASA Astrophysics Data System (ADS)
Niemann, R. C.; Cha, Y. S.; Hull, J. R.; Daugherty, M. A.; Buckles, W. E.
As part of the US Department of Energy's Superconductivity Pilot Center Program, Argonne National Laboratory and Superconductivity, Inc., are developing high-temperature superconductor (HTS) current leads suitable for application to superconducting magnetic energy storage systems. The principal objective of the development program is to design, construct, and evaluate the performance of HTS current leads suitable for near-term applications. Supporting objectives are to (1) develop performance criteria; (2) develop a detailed design; (3) analyze performance; (4) gain manufacturing experience in the areas of materials and components procurement, fabrication and assembly, quality assurance, and cost; (5) measure performance of critical components and the overall assembly; (6) identify design uncertainties and develop a program for their study; and (7) develop application-acceptance criteria.
ERIC Educational Resources Information Center
van Driel, Jan H.; Meirink, J. A.; van Veen, K.; Zwart, R. C.
2012-01-01
This review provides an overview of the the current state of research on professional development in science education. An analytical frame was used, based on what is known about PD from educational research. Clarke and Hollingsworth's model for teacher professional growth was also used to categorise the studies according to their aims and…
ERIC Educational Resources Information Center
Solak, Ekrem
2011-01-01
The aim of the article is to shed light on the historical development of language studies in military and social context and to compare the current status of NATO Stanag (Standard Agreement) 6001 language scale with Common European Framework (CEF). Language studies in military context date back to World War II and the emergence of Army Specialized…
ERIC Educational Resources Information Center
Kang, Myunghee; Kim, Seyoung; Yoon, Seonghye; Chung, Warren
2017-01-01
The purpose of this study was to set future directions of the Cyber Home Learning System in Korea based on its current status. The Cyber Home Learning System has been designed and used by K-12 students to study voluntarily at home using online lessons. The development process of the Cyber Home Learning System was composed of the following four…
DOT National Transportation Integrated Search
2011-07-01
This research study primarily addresses the current traffic characterization techniques used in Louisiana for pavement design practices in order to identify critical changes needed as well as certain gaps and areas of potential development in the tra...
Environmental risk factors for inflammatory bowel diseases: Evidence based literature review
Abegunde, Ayokunle T; Muhammad, Bashir H; Bhatti, Owais; Ali, Tauseef
2016-01-01
AIM: Advances in genetics and immunology have contributed to the current understanding of the pathogenesis of inflammatory bowel diseases (IBD). METHODS: The current opinion on the pathogenesis of IBD suggests that genetically susceptible individuals develop intolerance to dysregulated gut microflora (dysbiosis) and chronic inflammation develops as a result of environmental insults. Environmental exposures are innumerable with varying effects during the life course of individuals with IBD. Studying the relationship between environmental factors and IBD may provide the missing link to increasing our understanding of the etiology and increased incidence of IBD in recent years with implications for prevention, diagnosis, and treatment. Environmental factors are heterogeneous and genetic predisposition, immune dysregulation, or dysbiosis do not lead to the development of IBD in isolation. RESULTS: Current challenges in the study of environmental factors and IBD are how to effectively translate promising results from experimental studies to humans in order to develop models that incorporate the complex interactions between the environment, genetics, immunology, and gut microbiota, and limited high quality interventional studies assessing the effect of modifying environmental factors on the natural history and patient outcomes in IBD. CONCLUSION: This article critically reviews the current evidence on environmental risk factors for IBD and proposes directions for future research. PMID:27468219
NASA Astrophysics Data System (ADS)
Chen, Yi; Yang, Fei; Sun, Hao; Wu, Yi; Niu, Chunping; Rong, Mingzhe
2017-06-01
After current zero, which is the moment when the vacuum circuit breaker interrupts a vacuum arc, sheath development is the first process in the dielectric recovery process. An axial magnetic field (AMF) is widely used in the vacuum circuit breaker when the high-current vacuum arc is interrupted. Therefore, it is very important to study the influence of different AMF amplitudes on the sheath development. The objective of this paper is to study the influence of different AMF amplitudes on the sheath development from a micro perspective. Thus, the particle in cell-Monte Carlo collisions (PIC-MCC) method was adopted to develop the sheath development model. We compared the simulation results with the experimental results and then validated the simulation. We also obtained the speed of the sheath development and the energy density of the ions under different AMF amplitudes. The results showed that the larger the AMF amplitudes are, the faster the sheath develops and the lower the ion energy density is, meaning the breakdown is correspondingly more difficult.
Ider, Yusuf Ziya; Birgul, Ozlem; Oran, Omer Faruk; Arikan, Orhan; Hamamura, Mark J; Muftuler, L Tugan
2010-06-07
Fourier transform (FT)-based algorithms for magnetic resonance current density imaging (MRCDI) from one component of magnetic flux density have been developed for 2D and 3D problems. For 2D problems, where current is confined to the xy-plane and z-component of the magnetic flux density is measured also on the xy-plane inside the object, an iterative FT-MRCDI algorithm is developed by which both the current distribution inside the object and the z-component of the magnetic flux density on the xy-plane outside the object are reconstructed. The method is applied to simulated as well as actual data from phantoms. The effect of measurement error on the spatial resolution of the current density reconstruction is also investigated. For 3D objects an iterative FT-based algorithm is developed whereby the projected current is reconstructed on any slice using as data the Laplacian of the z-component of magnetic flux density measured for that slice. In an injected current MRCDI scenario, the current is not divergence free on the boundary of the object. The method developed in this study also handles this situation.
Single dose treatment of malaria - current status and perspectives.
Mischlinger, Johannes; Agnandji, Selidji T; Ramharter, Michael
2016-07-01
Despite increased international efforts for control and ultimate elimination, malaria remains a major health problem. Currently, artemisinin-based combination therapies are the treatment of choice for uncomplicated malaria exhibiting high efficacy in clinical trial settings in sub-Saharan Africa. However, their administration over a three-day period is associated with important problems of treatment adherence resulting in markedly reduced effectiveness of currently recommended antimalarials under real world settings. Antimalarial drug candidates and antimalarial drug combinations currently under advanced clinical development for the indication as single dose antimalarial therapy. Expert commentary: Several new drug candidates and combinations are currently undergoing pivotal proof-of-concept studies or clinical development programmes. The development of a single dose combination therapy would constitute a breakthrough in the control of malaria. Such an innovative treatment approach would simultaneously close the effectiveness gap of current three-day therapies and revolutionize population based interventions in the context of malaria elimination campaigns.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Yarnall, C.A.; Caruthers, J.R.
This study was performed under FUTURE LOOK, a joint Defense Nuclear Agency/Department of Energy (DNA/DOE) sponsored study. The intent of FUTURE LOOK is to identify and develop means of providing requisite security and survivability to the Non-Strategic Nuclear Forces (NSNF) in the Twenty-First Century. Our current thinking about the future world in Europe is summarized. In this report we develop four scenarios/stockpile cases to cover the spectrum of potential happenings in Europe; we also develop general security and survivability implications and recommendations for each case. The four cases are: (1) a substantially reduced (factor of 2--10) European stockpile; (2) amore » near-zero stockpile, with no Army weapons remaining in Europe; (3) current stockpile in Europe remains; and (4) current stockpile numbers remain, but aggressive modernization is allowed. We plan to use the information in this report to assist in developing detailed security and survivability options as part of our follow-on to FUTURE LOOK studies. 8 refs., 6 tabs.« less
Program Development for Primary School Teachers' Critical Thinking
ERIC Educational Resources Information Center
Boonjeam, Waraporn; Tesaputa, Kowat; Sri-ampai, Anan
2017-01-01
The objectives of this research were: 1) to study the elements and indicators of primary school teachers' critical thinking, 2) to study current situation, desirable situation, development technique, and need for developing the primary school teachers' critical thinking, 3) to develop the program for developing the primary school teachers'…
The Development of Professional Learning Community in Primary Schools
ERIC Educational Resources Information Center
Sompong, Samoot; Erawan, Prawit; Dharm-tad-sa-na-non, Sudharm
2015-01-01
The objectives of this research are: (1) To study the current situation and need for developing professional learning community in primary schools; (2) To develop the model for developing professional learning community, and (3) To study the findings of development for professional learning community based on developed model related to knowledge,…
NASA Technical Reports Server (NTRS)
Huang, N. E.; Flood, W. A.; Brown, G. S.
1975-01-01
The feasibility of remote sensing of current flows in the ocean and the remote sensing of ocean currents by backscattering cross section techniques was studied. It was established that for capillary waves, small scale currents could be accurately measured through observation of wave kinematics. Drastic modifications of waves by changing currents were noted. The development of new methods for the measurement of capillary waves are discussed. Improvement methods to resolve data processing problems are suggested.
Kinetic Simulation and Energetic Neutral Atom Imaging of the Magnetosphere
NASA Technical Reports Server (NTRS)
Fok, Mei-Ching H.
2011-01-01
Advanced simulation tools and measurement techniques have been developed to study the dynamic magnetosphere and its response to drivers in the solar wind. The Comprehensive Ring Current Model (CRCM) is a kinetic code that solves the 3D distribution in space, energy and pitch-angle information of energetic ions and electrons. Energetic Neutral Atom (ENA) imagers have been carried in past and current satellite missions. Global morphology of energetic ions were revealed by the observed ENA images. We have combined simulation and ENA analysis techniques to study the development of ring current ions during magnetic storms and substorms. We identify the timing and location of particle injection and loss. We examine the evolution of ion energy and pitch-angle distribution during different phases of a storm. In this talk we will discuss the findings from our ring current studies and how our simulation and ENA analysis tools can be applied to the upcoming TRIO-CINAMA mission.
Studying molecular changes during gravity perception and response in a single cell.
Cannon, Ashley E; Salmi, Mari L; Bushart, Thomas J; Roux, Stanley J
2015-01-01
Early studies revealed a highly predictable pattern of gravity-directed growth and development in Ceratopteris richardii spores. This makes the spores a valuable model system for the study of how a single cell senses and responds to the force of gravity. Gravity regulates both the direction and magnitude of a trans-cell calcium current in germinating spores, and the orientation of this current predicts the polarization of spore development. Molecular techniques have been developed to evaluate the transcriptomic and proteomic profiles of spores before and after gravity establishes the polarity of their development. Here we describe these techniques, along with protocols for sterilizing the spores, sowing them in a solid or liquid growth media, and evaluating germination.
ERIC Educational Resources Information Center
Zernovoj, Alexander
2007-01-01
This study provides a complete review of discussion and development leading up to the current trends in Deaf Studies curriculum development, and also analyzes existing known curriculum (or curriculum-like) materials to help inform development of an ideal standards-based Deaf Studies curriculum. The common shared arguments identified in this…
An Investigation into Geography Teachers' Use of Current Events in Geography Classes
ERIC Educational Resources Information Center
Degirmenci, Yavuz; Ilter, Ilhan
2017-01-01
This study aimed to investigate the extent to which geography teachers use current events within the context of their geography instruction, their sources of information about current events, the methods and techniques they adopt while using current events in their teaching and the skills and values they expect their students to develop. The…
Guan, Dongxu; Horton, Leslie R.; Armstrong, William E.
2011-01-01
Potassium channels regulate numerous aspects of neuronal excitability, and several voltage-gated K+ channel subunits have been identified in pyramidal neurons of rat neocortex. Previous studies have either considered the development of outward current as a whole or divided currents into transient, A-type and persistent, delayed rectifier components but did not differentiate between current components defined by α-subunit type. To facilitate comparisons of studies reporting K+ currents from animals of different ages and to understand the functional roles of specific current components, we characterized the postnatal development of identified Kv channel-mediated currents in pyramidal neurons from layers II/III from rat somatosensory cortex. Both the persistent/slowly inactivating and transient components of the total K+ current increased in density with postnatal age. We used specific pharmacological agents to test the relative contributions of putative Kv1- and Kv2-mediated currents (100 nM α-dendrotoxin and 600 nM stromatoxin, respectively). A combination of voltage protocol, pharmacology, and curve fitting was used to isolate the rapidly inactivating A-type current. We found that the density of all identified current components increased with postnatal age, approaching a plateau at 3–5 wk. We found no significant changes in the relative proportions or kinetics of any component between postnatal weeks 1 and 5, except that the activation time constant for A-type current was longer at 1 wk. The putative Kv2-mediated component was the largest at all ages. Immunocytochemistry indicated that protein expression for Kv4.2, Kv4.3, Kv1.4, and Kv2.1 increased between 1 wk and 4–5 wk of age. PMID:21451062
Guan, Dongxu; Horton, Leslie R; Armstrong, William E; Foehring, Robert C
2011-06-01
Potassium channels regulate numerous aspects of neuronal excitability, and several voltage-gated K(+) channel subunits have been identified in pyramidal neurons of rat neocortex. Previous studies have either considered the development of outward current as a whole or divided currents into transient, A-type and persistent, delayed rectifier components but did not differentiate between current components defined by α-subunit type. To facilitate comparisons of studies reporting K(+) currents from animals of different ages and to understand the functional roles of specific current components, we characterized the postnatal development of identified Kv channel-mediated currents in pyramidal neurons from layers II/III from rat somatosensory cortex. Both the persistent/slowly inactivating and transient components of the total K(+) current increased in density with postnatal age. We used specific pharmacological agents to test the relative contributions of putative Kv1- and Kv2-mediated currents (100 nM α-dendrotoxin and 600 nM stromatoxin, respectively). A combination of voltage protocol, pharmacology, and curve fitting was used to isolate the rapidly inactivating A-type current. We found that the density of all identified current components increased with postnatal age, approaching a plateau at 3-5 wk. We found no significant changes in the relative proportions or kinetics of any component between postnatal weeks 1 and 5, except that the activation time constant for A-type current was longer at 1 wk. The putative Kv2-mediated component was the largest at all ages. Immunocytochemistry indicated that protein expression for Kv4.2, Kv4.3, Kv1.4, and Kv2.1 increased between 1 wk and 4-5 wk of age.
ERIC Educational Resources Information Center
Ajake, Uchenna E.; Omori, Anne E.; Essien, Margaret
2011-01-01
The study highlighted the Nigerian Universities' new sustainable development strategies: emphasizes the role that entrepreneurship education can play in both raising awareness among young people about sustainable development and giving them the skills to put sustainable development into practice. Universities place priority on the development of…
The reasons for betel-quid chewing scale: assessment of factor structure, reliability, and validity
2014-01-01
Background Despite the fact that betel-quid is one of the most commonly used psychoactive substances worldwide and a major risk-factor for head-and-neck cancer incidence and mortality globally, currently no standardized instrument is available to assess the reasons why individuals chew betel-quid. A measure to assess reasons for chewing betel-quid could help researchers and clinicians develop prevention and treatment strategies. In the current study, we sought to develop and evaluate a self-report instrument for assessing the reasons for chewing betel quid which contributes toward the goal of developing effective interventions to reduce betel quid chewing in vulnerable populations. Methods The current study assessed the factor structure, reliability and convergent validity of the Reasons for Betel-quid Chewing Scale (RBCS), a newly developed 10 item measure adapted from several existing “reasons for smoking” scales. The measure was administered to 351 adult betel-quid chewers in Guam. Results Confirmatory factor analysis of this measure revealed a three factor structure: reinforcement, social/cultural, and stimulation. Further tests revealed strong support for the internal consistency and convergent validity of this three factor measure. Conclusion The goal of designing an intervention to reduce betel-quid chewing necessitates an understanding of why chewers chew; the current study makes considerable contributions towards that objective. PMID:24889863
The reasons for betel-quid chewing scale: assessment of factor structure, reliability, and validity.
Little, Melissa A; Pokhrel, Pallav; Murphy, Kelle L; Kawamoto, Crissy T; Suguitan, Gil S; Herzog, Thaddeus A
2014-06-03
Despite the fact that betel-quid is one of the most commonly used psychoactive substances worldwide and a major risk-factor for head-and-neck cancer incidence and mortality globally, currently no standardized instrument is available to assess the reasons why individuals chew betel-quid. A measure to assess reasons for chewing betel-quid could help researchers and clinicians develop prevention and treatment strategies. In the current study, we sought to develop and evaluate a self-report instrument for assessing the reasons for chewing betel quid which contributes toward the goal of developing effective interventions to reduce betel quid chewing in vulnerable populations. The current study assessed the factor structure, reliability and convergent validity of the Reasons for Betel-quid Chewing Scale (RBCS), a newly developed 10 item measure adapted from several existing "reasons for smoking" scales. The measure was administered to 351 adult betel-quid chewers in Guam. Confirmatory factor analysis of this measure revealed a three factor structure: reinforcement, social/cultural, and stimulation. Further tests revealed strong support for the internal consistency and convergent validity of this three factor measure. The goal of designing an intervention to reduce betel-quid chewing necessitates an understanding of why chewers chew; the current study makes considerable contributions towards that objective.
ERIC Educational Resources Information Center
Lin, Chia-Fen
2016-01-01
Preschool curriculum reform is currently underway in Taiwan. Privately-managed public preschools (PMPPs) currently play the role of bellwethers because they stand halfway between public and private preschools, and serve as testing grounds for curriculum reforms promoted by the government. This study originated from Curriculum Development Program…
ERIC Educational Resources Information Center
Agarwal, Parul Dharmani; Kiran, Ravi; Verma, Anil Kumar
2012-01-01
Problem Statement: The current higher learning institutions in developed countries have adapted to their changing role in a knowledge-based society It is time for developing countries like India to focus on Knowledge Management thus, the current study presents research undertaken in understanding the implication of Knowledge Management in the…
Load flows and faults considering dc current injections
NASA Technical Reports Server (NTRS)
Kusic, G. L.; Beach, R. F.
1991-01-01
The authors present novel methods for incorporating current injection sources into dc power flow computations and determining network fault currents when electronic devices limit fault currents. Combinations of current and voltage sources into a single network are considered in a general formulation. An example of relay coordination is presented. The present study is pertinent to the development of the Space Station Freedom electrical generation, transmission, and distribution system.
ERIC Educational Resources Information Center
Stedman, Donald J., Ed.
Six papers discuss some of the current issues in the field of mental retardation and human development. Epidemiology of mental retardation from a sociological and clinical point of view is analyzed by Jane R. Mercer, based on studies of mental retardation in the community in Pomona, California. The role of genetics and intra-uterine diagnosis of…
NASA Astrophysics Data System (ADS)
Astafiev, A.; Orlov, A.; Privezencev, D.
2018-01-01
The article is devoted to the development of technology and software for the construction of positioning and control systems in industrial plants based on aggregation to determine the current storage area using computer vision and radiofrequency identification. It describes the developed of the project of hardware for industrial products positioning system in the territory of a plant on the basis of radio-frequency grid. It describes the development of the project of hardware for industrial products positioning system in the plant on the basis of computer vision methods. It describes the development of the method of aggregation to determine the current storage area using computer vision and radiofrequency identification. Experimental studies in laboratory and production conditions have been conducted and described in the article.
The West Virginia Consortium for Faculty and Course Development in International Studies.
ERIC Educational Resources Information Center
Peterson, Sophia; Maxwell, John
The West Virginia Consortium for Faculty and Course Development in International Studies (FACDIS) is described in this report. FACDIS, a consortium of 21 West Virginia institutions of higher education, assists in international studies course development, revision, and enrichment. It also helps faculty remain current in their fields and in new…
Single Particle Orientation and Rotational Tracking (SPORT) in biophysical studies
NASA Astrophysics Data System (ADS)
Gu, Yan; Ha, Ji Won; Augspurger, Ashley E.; Chen, Kuangcai; Zhu, Shaobin; Fang, Ning
2013-10-01
The single particle orientation and rotational tracking (SPORT) techniques have seen rapid development in the past 5 years. Recent technical advances have greatly expanded the applicability of SPORT in biophysical studies. In this feature article, we survey the current development of SPORT and discuss its potential applications in biophysics, including cellular membrane processes and intracellular transport.The single particle orientation and rotational tracking (SPORT) techniques have seen rapid development in the past 5 years. Recent technical advances have greatly expanded the applicability of SPORT in biophysical studies. In this feature article, we survey the current development of SPORT and discuss its potential applications in biophysics, including cellular membrane processes and intracellular transport. Electronic supplementary information (ESI) available: Three supplementary movies and an experimental section. See DOI: 10.1039/c3nr02254d
Intercultural Adaptation and Validity Study: Universal Science Literacy Scale (USLS)
ERIC Educational Resources Information Center
Çelik, Cüneyd; Can, Sendil
2017-01-01
The purpose of the current study is to adapt "The Universal Science Literacy Scale" developed by Mun, Shin, Lee, Kim, Choi, Choi and Krajcik into Turkish. The study group of the current research is comprised of a total of 645 pre-service science teachers from 6 different universities of Turkey. In the first stage of the adaptation study,…
Tosti, Elisabetta; Gallo, Alessandra; Silvestre, Francesco
2011-01-01
Electrophysiological techniques were used to study the role of ion currents in the ascidian Ciona intestinalis oocyte plasma membrane during different stages of growth, meiosis, fertilization and early development. Three stages of immature oocytes were discriminated in the ovary, with the germinal vesicle showing specific different features of growth and maturation. Stage-A (pre-vitellogenic) oocytes exhibited the highest L-type calcium current activity and were incompetent for meiosis resumption. Stage-B (vitellogenic) oocytes showed a progressive disappearance of calcium currents and the first appearance of sodium currents that remained high during the maturation process, up to the post-vitellogenic stage-C oocytes. The latter had acquired meiotic competence, undergoing spontaneous in vitro maturation and interacting with the spermatozoon. However, fertilized oocytes did not produce normal larvae, suggesting that cytoplasmic maturation may affect embryo development. In mature oocytes at the metaphase I stage, sodium currents were present and remained high up to the zygote stage. Oocytes fertilized in the absence of sodium showed significant reduction of the fertilization current amplitude and high development of anomalous "rosette" embryos. Current amplitudes became negligible in embryos at the 2- and 4-cell stage, whereas resumption of all the current activities occurred at the 8-cell embryo. Taken together, these results suggest: (i) an involvement of L-type calcium currents in initial oocyte meiotic progression and growth; (ii) a role of sodium currents at fertilization; (iii) a role of the fertilization current in ensuring normal embryo development. Copyright © 2011 Wiley Periodicals, Inc.
Current and future technology in radial and axial gas turbines
NASA Technical Reports Server (NTRS)
Rohlik, H. E.
1983-01-01
Design approaches and flow analysis techniques currently employed by aircraft engine manufacturers are assessed. Studies were performed to define the characteristics of aircraft and engines for civil missions of the 1990's and beyond. These studies, coupled with experience in recent years, identified the critical technologies needed to meet long range goals in fuel economy and other operating costs. Study results, recent and current research and development programs, and an estimate of future design and analytic capabilities are discussed.
Does Critical Mass Matter? Women's Political Representation and Child Health in Developing Countries
ERIC Educational Resources Information Center
Swiss, Liam; Fallon, Kathleen M.; Burgos, Giovani
2012-01-01
Studies on developed countries demonstrate that an increase in women legislators leads to a prioritization in health, an increase in social policy spending, and a decrease in poverty. Women representatives could therefore improve development trajectories in developing countries; yet, currently, no cross-national and longitudinal studies explore…
How Advertising History Helps Explain Current Practices.
ERIC Educational Resources Information Center
Lanfranco, Leonard W.
Students majoring in advertising can benefit from a study of that field in its historical context because such study helps them to understand current practices and to foresee future developments. One model of teaching advertising history within a required course about advertising and society begins with some basic definitions of the advertising…
MOOCs: Expectations and Reality. Full Report
ERIC Educational Resources Information Center
Hollands, Fiona M.; Tirthali, Devayani
2014-01-01
The purpose of this study was to investigate the goals of institutions that are currently developing and delivering Massive Open Online Courses (MOOCs) and to assess the current evidence as to whether these goals are being met. A qualitative study was conducted comprising interviews of 83 individuals across 62 institutions including public and…
ERIC Educational Resources Information Center
Box, Wilford Winston
A study was conducted at Southwest Texas Junior College (STJC) to assess current management practices used by the physical plant maintenance department (PPMD) and to develop a strategic plan for physical plant management. Procedures included an analysis of current management practices and systems that affect physical resources, and periodic and…
Arab, Abeer; Alatassi, Abdulaleem; Alattas, Elias; Alzoraigi, Usamah; AlZaher, Zaki; Ahmad, Abdulaziz; Albabtain, Hesham; Boker, Abdulaziz
2017-01-01
The educational programs in the Saudi Commission for Health Specialties are developing rapidly in the fields of technical development. Such development is witnessed, particularly in the scientific areas related to what is commonly known as evidence-based medicine. This review highlights the critical need and importance of integrating simulation into anesthesia training and assessment. Furthermore, it describes the current utilization of simulation in anesthesia and critical care assessment process. PMID:28442961
Biorefineries for the production of top building block chemicals and their derivatives.
Choi, Sol; Song, Chan Woo; Shin, Jae Ho; Lee, Sang Yup
2015-03-01
Due to the growing concerns on the climate change and sustainability on petrochemical resources, DOE selected and announced the bio-based top 12 building blocks and discussed the needs for developing biorefinery technologies to replace the current petroleum based industry in 2004. Over the last 10 years after its announcement, many studies have been performed for the development of efficient technologies for the bio-based production of these chemicals and derivatives. Now, ten chemicals among these top 12 chemicals, excluding the l-aspartic acid and 3-hydroxybutyrolactone, have already been commercialized or are close to commercialization. In this paper, we review the current status of biorefinery development for the production of these platform chemicals and their derivatives. In addition, current technological advances on industrial strain development for the production of platform chemicals using micro-organisms will be covered in detail with case studies on succinic acid and 3-hydroxypropionic acid as examples. Copyright © 2015 International Metabolic Engineering Society. Published by Elsevier Inc. All rights reserved.
ERIC Educational Resources Information Center
Sai-rat, Wipa; Tesaputa, Kowat; Sriampai, Anan
2015-01-01
The objectives of this study were 1) to study the current state of and problems with the Learning Organization of the Primary School Network, 2) to develop a Learning Organization Model for the Primary School Network, and 3) to study the findings of analyses conducted using the developed Learning Organization Model to determine how to develop the…
Integrating 3D Visualization and GIS in Planning Education
ERIC Educational Resources Information Center
Yin, Li
2010-01-01
Most GIS-related planning practices and education are currently limited to two-dimensional mapping and analysis although 3D GIS is a powerful tool to study the complex urban environment in its full spatial extent. This paper reviews current GIS and 3D visualization uses and development in planning practice and education. Current literature…
Cargo Logistics Airlift Systems Study (CLASS). Volume 5: Summary
NASA Technical Reports Server (NTRS)
Burby, R. J.; Kuhlman, W. H.
1980-01-01
Findings and conclusions derived during the study of freighter aircraft requirements to the year 2008 are summarized. These results represent the stepping off point for the much needed coordinated planning efforts by government agencies, the airlines, the users, and the aircraft manufacturers. The methodology utilized in the investigations is shown. The analysis of the current system encompassed evaluations of the past and current cargo markets and on sight surveys of airport and cargo terminals. The findings that resulted provided the basis for formulating the case study procedures, developing the future scenario, and developing the future cargo market demand.
NASA Astrophysics Data System (ADS)
Stolle-McAllister, Kathy; Sto. Domingo, Mariano R.; Carrillo, Amy
2011-02-01
The Meyerhoff Scholarship Program (MSP) is widely recognized for its comprehensive approach of integrating students into the science community. The supports provided by the program aim to develop students, primarily Blacks, into scientists by offering them academic, social, and professional opportunities to achieve their academic and career goals. The current study allowed for a rich understanding of the perceptions of current Meyerhoff students and Meyerhoff alumni about how the program works. Three groups of MSP students were included in the study: (1) new Meyerhoff students participating in Summer Bridge ( n = 45), (2) currently enrolled Meyerhoff students ( n = 92), and (3) graduates of the MSP who were currently enrolled in STEM graduate studies or had completed an advanced STEM degree ( n = 19). Students described the importance of several key aspects of the MSP: financial support, the Summer Bridge Program, formation of Meyerhoff identity, belonging to the Meyerhoff family, and developing networks—all of which serve to integrate students both academically and socially.
Stolle-McAllister, Kathy; Sto. Domingo, Mariano R.; Carrillo, Amy
2011-01-01
The Meyerhoff Scholarship Program (MSP) is widely recognized for its comprehensive approach of integrating students into the science community. The supports provided by the program aim to develop students, primarily Blacks, into scientists by offering them academic, social, and professional opportunities to achieve their academic and career goals. The current study allowed for a rich understanding of the perceptions of current Meyerhoff students and Meyerhoff alumni about how the program works. Three groups of MSP students were included in the study: 1) new Meyerhoff students participating in Summer Bridge (n=45), 2) currently enrolled Meyerhoff students (n=92), and 3) graduates of the MSP who were currently enrolled in STEM graduate studies or had completed an advanced STEM degree (n=19). Students described the importance of several key aspects of the Meyerhoff Scholars Program: financial support, the Summer Bridge Program, formation of Meyerhoff identity, belonging to the Meyerhoff family, and developing networks - all of which serve to integrate students both academically and socially. PMID:21850153
Voltage-Clamp Studies on Uterine Smooth Muscle
Anderson, Nels C.
1969-01-01
These studies have developed and tested an experimental approach to the study of membrane ionic conductance mechanisms in strips of uterine smooth muscle. The experimental and theoretical basis for applying the double sucrose-gap technique is described along with the limitations of this system. Nonpropagating membrane action potentials were produced in response to depolarizing current pulses under current-clamp conditions. The stepwise change of membrane potential under voltage-clamp conditions resulted in a family of ionic currents with voltage- and time-dependent characteristics. In sodium-free solution the peak transient current decreased and its equilibrium potential shifted along the voltage axis toward a more negative internal potential. These studies indicate a sodium-dependent, regenerative excitation mechanism. PMID:5796366
ERIC Educational Resources Information Center
Killen, Melanie; Smetana, Judith
2006-01-01
The psychological study of moral development has expanded greatly, both in terms of the diversity of theoretical perspectives that are represented in the field, as well as in the range of topics that have been studied. This "Handbook of Moral Development" represents the diversity and multidisciplinary influences on current theorizing about the…
White Matter Development during Adolescence as Shown by Diffusion MRI
ERIC Educational Resources Information Center
Schmithorst, Vincent J.; Yuan, Weihong
2010-01-01
Previous volumetric developmental MRI studies of the brain have shown white matter development continuing through adolescence and into adulthood. This review presents current findings regarding white matter development and organization from diffusion MRI studies. The general trend during adolescence (age 12-18 years) is towards increasing…
Student Misbehaviors in Online Classrooms: Scale Development and Validation
ERIC Educational Resources Information Center
Li, Li; Titsworth, Scott
2015-01-01
The current program of research included two studies that developed the Student Online Misbehaviors (SOMs) scale and explored relationships between the SOMs and various classroom communication processes and outcomes. The first study inductively developed initial SOM typologies and tested factor structure via an exploratory factor analysis.…
Development and Maintenance of Identity in Aging Community Music Participants
ERIC Educational Resources Information Center
Dyer, William Leonard
2016-01-01
This ethnographic study contextualized identity development and maintenance within the field of community music through case studies of four performing groups and interviews with seven current members. The underlying question guiding this research was how does participatory music making contribute to the development and maintenance of identity in…
Emergent Literacy: A Polyphony of Perspectives. CIERA Report.
ERIC Educational Resources Information Center
Yaden, David B., Jr.; Rowe, Deborah W.; MacGillivray, Laurie
This paper reviews current developments in the field of emergent literacy (the study of reading and writing behaviors that develop into conventional literacy). The review includes studies that look at preschoolers' emerging literacy in homes, day-care environments, and kindergartens and that focus on children's development of literacy knowledge…
García-Delgado, Neivys; Velasco, Myrian; Sánchez-Soto, Carmen; Díaz-García, Carlos Manlio; Hiriart, Marcia
2018-01-01
Pancreatic beta cells during the first month of development acquire functional maturity, allowing them to respond to variations in extracellular glucose concentration by secreting insulin. Changes in ionic channel activity are important for this maturation. Within the voltage-gated calcium channels (VGCC), the most studied channels are high-voltage-activated (HVA), principally L-type; while low-voltage-activated (LVA) channels have been poorly studied in native beta cells. We analyzed the changes in the expression and activity of VGCC during the postnatal development in rat beta cells. We observed that the percentage of detection of T-type current increased with the stage of development. T-type calcium current density in adult cells was higher than in neonatal and P20 beta cells. Mean HVA current density also increased with age. Calcium current behavior in P20 beta cells was heterogeneous; almost half of the cells had HVA current densities higher than the adult cells, and this was independent of the presence of T-type current. We detected the presence of α1G, α1H, and α1I subunits of LVA channels at all ages. The Cav 3.1 subunit (α1G) was the most expressed. T-type channel blockers mibefradil and TTA-A2 significantly inhibited insulin secretion at 5.6 mM glucose, which suggests a physiological role for T-type channels at basal glucose conditions. Both, nifedipine and TTA-A2, drastically decreased the beta-cell subpopulation that secretes more insulin, in both basal and stimulating glucose conditions. We conclude that changes in expression and activity of VGCC during the development play an important role in physiological maturation of beta cells. PMID:29556214
NASA Astrophysics Data System (ADS)
Roux, Stanley; Porterfield, D. Marshall; Haque, Aeraj Ul; Bushart, Thomas
The vector of gravity sets the direction of polarized development of single spore cells of the fern Ceratopteris richardii after light initiates their germination. Gravity also sets the direction of a trans-cell calcium current, which enters the cell along its bottom and exits it from its top. The direction of this current predicts the subsequent direction of spore development, and blocking this current with calcium channel blockers randomizes the direction of subsequent development. Recently the laboratory of D. Marshall Porterfield (Purdue University) developed a microchip device that can measure the direction and magnitude of the trans-spore calcium current in real time. Our laboratory in collaboration with Porterfield's recently found that this current inverts rapidly when the cells are turned upside down and that the magnitude of the current rises and falls with the magnitude of the g-force when these cells are tested in parabolic flight on the DC-9 aircraft. We assume that the gravity-directed entry of calcium into these cells is through calcium channels and its exit is through calcium pumps. Here we report our studies of a calcium pump that is highly expressed in the spores during the period when gravity is setting the direction of the calcium current, and we describe pharmacological tests of the relative importance of calcium pumps in maintaining the calcium current and in controlling the direction of subsequent spore development. We found that inhibitors that block the activity of calcium pumps also greatly depress the trans-cell current, but, surprisingly, have little effect on the ability of gravity to set the direction of spore development. These results, in combination with earlier findings, indicate that the gravity-directed opening of calcium channels along the bottom of spore cells plays a more important role in directing subsequent spore development than the activity of calcium pumps, despite the importance of these pumps in maintaining the trans-cell calcium current. Supported by NASA grants NAG2-1586 and NAG10-295 to S. J. R.
US computer research networks: Current and future
NASA Technical Reports Server (NTRS)
Kratochvil, D.; Sood, D.; Verostko, A.
1989-01-01
During the last decade, NASA LeRC's Communication Program has conducted a series of telecommunications forecasting studies to project trends and requirements and to identify critical telecommunications technologies that must be developed to meet future requirements. The Government Networks Division of Contel Federal Systems has assisted NASA in these studies, and the current study builds upon these earlier efforts. The current major thrust of the NASA Communications Program is aimed at developing the high risk, advanced, communications satellite and terminal technologies required to significantly increase the capacity of future communications systems. Also, major new technological, economic, and social-political events and trends are now shaping the communications industry of the future. Therefore, a re-examination of future telecommunications needs and requirements is necessary to enable NASA to make management decisions in its Communications Program and to ensure the proper technologies and systems are addressed. This study, through a series of Task Orders, is helping NASA define the likely communication service needs and requirements of the future and thereby ensuring that the most appropriate technology developments are pursued.
On-Line, Off-Campus but in the Flow: Learning from Peers in Development Studies
ERIC Educational Resources Information Center
Beckmann, Elizabeth A.; Kilby, Patrick
2008-01-01
Development workers studying at the graduate level benefit from exposure to the great variety of cultures and worldviews. In the Australian National University's Master of Applied Anthropology and Participatory Development (MAAPD) program, peer learning is giving current and future development workers in the field and in the classroom the chance…
Home Study Course Development Handbook.
ERIC Educational Resources Information Center
Lambert, Michael P., Ed.; Welch, Sally R., Ed.
Intended for independent study directors, course authors, and directors of home based or distance learning projects, this collection of current, practical guides on correspondence course development contains fourteen chapters authored by practicing home study educators and experts in their field. From Theory to Practice lists steps in course…
Epidemiological Studies to Support the Development of Next Generation Influenza Vaccines.
Petrie, Joshua G; Gordon, Aubree
2018-03-26
The National Institute of Allergy and Infectious Diseases recently published a strategic plan for the development of a universal influenza vaccine. This plan focuses on improving understanding of influenza infection, the development of influenza immunity, and rational design of new vaccines. Epidemiological studies such as prospective, longitudinal cohort studies are essential to the completion of these objectives. In this review, we discuss the contributions of epidemiological studies to our current knowledge of vaccines and correlates of immunity, and how they can contribute to the development and evaluation of the next generation of influenza vaccines. These studies have been critical in monitoring the effectiveness of current influenza vaccines, identifying issues such as low vaccine effectiveness, reduced effectiveness among those who receive repeated vaccination, and issues related to egg adaptation during the manufacturing process. Epidemiological studies have also identified population-level correlates of protection that can inform the design and development of next generation influenza vaccines. Going forward, there is an enduring need for epidemiological studies to continue advancing knowledge of correlates of protection and the development of immunity, to evaluate and monitor the effectiveness of next generation influenza vaccines, and to inform recommendations for their use.
A Phenomenological Reinterpretation of Horner's Fear of Success in Terms of Social Class
ERIC Educational Resources Information Center
Ivers, Jo-Hanna; Downes, P.
2012-01-01
The current study developed the concept of fear of success that was originally examined by Martina Horner (1970; "Journal of Social Issues", 28(2), 157-175, 1972). The key dimension in Horner's (1970; "Journal of Social Issues", 28(2), 157-175, 1972) studies was gender. The key dimension in the current study was social class. It was hypothesised…
Unimanual Performance across the Age Span
ERIC Educational Resources Information Center
Bryden, P.J.; Roy, E.A.
2005-01-01
The purpose of the current investigation was to examine the age-related changes in the performance of the two hands on the Annett pegboard (Annett, 1970). The current study was part of a large-scale study investigating the development of unimanual and bimanual performance. Three hundred and two right-handed individuals participated in the present…
ERIC Educational Resources Information Center
Nichols, Tanya M.; Kotchick, Beth A.; Barry, Carolyn McNamara; Haskins, Deborah G.
2010-01-01
The current study examined the association between multiple systems of influence (adolescent, family, and community) and the educational aspirations of African American adolescents. Guided by ecological and integrative models of child development, in the current study the authors examined the association between the educational aspirations of 130…
Development of the Academic Performance Perception Scale
ERIC Educational Resources Information Center
Gur, Recep
2017-01-01
Purpose: While numerous studies about academic performance that focused on only one factor, studies aiming to measure academicians' perceptions across many factors have not been observed in the literature. The current study aims to fill this gap and become a resource for upcoming studies. The aim of this study is to develop a valid and reliable…
ERIC Educational Resources Information Center
Udall, Morris K.
This report reviews America's current energy position. The energy sources studied include oil and gas, coal, nuclear energy, solar energy, and geothermal energy. Each source is analyzed in terms of current use, technology for extracting and developing the energy, research and development funding, and projections for future consumption and…
[Role of vitamin D in allergic diseases: Current research status].
Sperl, A; Klimek, L
2015-05-01
Recent research has focused on the relationship between vitamin D and allergy development. Results show that on the one hand a vitamin D deficiency can be responsible for the emergence of allergies, however, on the other hand a vitamin-D (over-) substitution was also seen in context with an increased allergy development. This article provides an overview on the current state of research and points at the problematic aspects that accompany the assessment of these studies. The paradoxic effect of vitamin D is currently being explained by epigenetic programming in pregnancy, by too low vitamin-D levels or excessive supplementation in newborns. Very recently, a gender-specific impact of vitamin D is also being discussed. For a final assessment of vitamin-D effects on the emergence of allergies, further research is necessary. Due to a high level of heterogeneity among current observational studies regarding central aspects of the discussion, randomised clinical trials are recommended.
A thermal shield concept for the Solar Probe mission
NASA Technical Reports Server (NTRS)
Miyake, Robert N.; Millard, Jerry M.; Randolph, James E.
1991-01-01
The Solar Probe spacecraft will travel to within 4 solar radii of the sun's center while performing a variety of fundamental experiments in space physics. Exposure to 2900 earth suns (400 W/sq cm) at perihelion imposes severe thermal and material demands on a solar shield system designed to protect the payload that will reside within the shield's shadow envelope or umbra. The design of the shield subsystem is a thermal/materials challenge requiring new technology development. While currently in the preproject study phase, anticipating a 1995 project start, shield preliminary design efforts are currently underway. This paper documents the current status of the mission concept, the materials issues, the configuration concept for the shield subsystem, the current configuration studies performed to date, and the required material testing to provide a database to support a design effort required to develop the shield subsystem.
Comparative study of superconducting fault current limiter both for LCC-HVDC and VSC-HVDC systems
NASA Astrophysics Data System (ADS)
Lee, Jong-Geon; Khan, Umer Amir; Lim, Sung-Woo; Shin, Woo-ju; Seo, In-Jin; Lee, Bang-Wook
2015-11-01
High Voltage Direct Current (HVDC) system has been evaluated as the optimum solution for the renewable energy transmission and long-distance power grid connections. In spite of the various advantages of HVDC system, it still has been regarded as an unreliable system compared to AC system due to its vulnerable characteristics on the power system fault. Furthermore, unlike AC system, optimum protection and switching device has not been fully developed yet. Therefore, in order to enhance the reliability of the HVDC systems mitigation of power system fault and reliable fault current limiting and switching devices should be developed. In this paper, in order to mitigate HVDC fault, both for Line Commutated Converter HVDC (LCC-HVDC) and Voltage Source Converter HVDC (VSC-HVDC) system, an application of resistive superconducting fault current limiter which has been known as optimum solution to cope with the power system fault was considered. Firstly, simulation models for two types of LCC-HVDC and VSC-HVDC system which has point to point connection model were developed. From the designed model, fault current characteristics of faulty condition were analyzed. Second, application of SFCL on each types of HVDC system and comparative study of modified fault current characteristics were analyzed. Consequently, it was deduced that an application of AC-SFCL on LCC-HVDC system with point to point connection was desirable solution to mitigate the fault current stresses and to prevent commutation failure in HVDC electric power system interconnected with AC grid.
A numerical study on the evolution of the wind-driven circulation in the Yellow Sea in winter
NASA Astrophysics Data System (ADS)
Tak, Y. J.; Cho, Y. K.
2016-02-01
The Yellow Sea is a semi-enclosed marginal sea and its circulation in winter is affected by the winter monsoon. In previous studies, it was found that the circulation of the Yellow Sea in winter consists of downwind and upwind currents. Downwind currents consisting of the Korean Coast Current (KCC) and the Chinese Coast Current (CCC) flow along the boundary of the Yellow Sea, whereas an upwind current consisting of the Yellow Sea Warm Current (YSWC) flows along the central trough of the Yellow Sea. Although some characteristics of such currents and the driving forces of the circulation have been studied by many scientists, the evolution of these currents has received little attention. So, the wind-driven circulation in the Yellow Sea was simulated to explain the changing pattern of these currents in winter and their evolutions were explored by the time-lagged correlation for winter season. According to the lagged correlation, downwind currents occurred in surface layer without a time lag. These downwind currents were more sensitive in the Chinese coast than that in the Korean coast. There is one day time-lag between the wind and the upwind flow developing in the Yellow Sea trough. The YSWC was shifted to the west of the trough after two days and then the KCC strengthened at the same time. It implied the westward shift of the YSWC and the clockwise circulation is developed, two days after the wind blows. The clockwise circulation was one of the reasons that the KCC was stronger than the CCC although the CCC was more sensitive to the wind than the KCC. The clockwise circulation also made the YSWC stronger in the inner YS than it at the entrance of the YS.
Alzheimer’s Disease Drug Development in 2008 and Beyond: Problems and Opportunities
Becker, Robert E.; Greig, Nigel H.
2008-01-01
Recently, a number of Alzheimer’s disease (AD) multi-center clinical trials (CT) have failed to provide statistically significant evidence of drug efficacy. To test for possible design or execution flaws we analyzed in detail CTs for two failed drugs that were strongly supported by preclinical evidence and by proven CT AD efficacy for other drugs in their class. Studies of the failed commercial trials suggest that methodological flaws may contribute to the failures and that these flaws lurk within current drug development practices ready to impact other AD drug development [1]. To identify and counter risks we considered the relevance to AD drug development of the following factors: (1) effective dosing of the drug product, (2) reliable evaluations of research subjects, (3) effective implementation of quality controls over data at research sites, (4) resources for practitioners to effectively use CT results in patient care, (5) effective disease modeling, (6) effective research designs. New drugs currently under development for AD address a variety of specific mechanistic targets. Mechanistic targets provide AD drug development opportunities to escape from many of the factors that currently undermine AD clinical pharmacology, especially the problems of inaccuracy and imprecision associated with using rated outcomes. In this paper we conclude that many of the current problems encountered in AD drug development can be avoided by changing practices. Current problems with human errors in clinical trials make it difficult to differentiate drugs that fail to evidence efficacy from apparent failures due to Type II errors. This uncertainty and the lack of publication of negative data impede researchers’ abilities to improve methodologies in clinical pharmacology and to develop a sound body of knowledge about drug actions. We consider the identification of molecular targets as offering further opportunities for overcoming current failures in drug development. PMID:18690832
Suliman, Shireen; Al-Mohammed, Ahmed; Al Mohanadi, Dabia; Allen, Margaret; Bylund, Carma L
2018-01-01
Purpose Mentoring plays a vital role in academic productivity, personal development, and career guidance for students, residents, fellows, and junior faculty. A culture of mentoring is spreading across residency and fellowship training programs in Hamad Medical Corporation, the main teaching tertiary care facility in Qatar. However, there is insufficient knowledge about the current practice of mentoring in these programs. Methods We conducted a cross-sectional study by surveying all faculty and trainees in all residency and fellowship training programs in Qatar. Each completed a web-based questionnaire that asked about the current experience, self-efficacy and measures of improvement of the current practice of mentoring across training programs. Results A total of 393/650 faculty members (61%), 187/250 fellows (74%), and 405/650 residents (62%) responded to the two surveys. Most (74% of faculty members) reported being current mentors, while 67% of residents and fellows reported that they currently have mentors. Faculty who received training in mentoring and those who had an established formal mentoring program in their departments were more likely to enroll in mentoring than others (86%, P<0.01; 71%, P<0.05%, respectively). Trainees suggested that the two main areas to improve the current mentoring initiative in their departments were to develop a structured mentoring program and to train the mentors. Content analysis revealed participants’ confusion differentiating between the terms mentoring and supervision. Conclusion Based on the current study, many existing mentoring relationships have an evident confusion between supervision and mentoring roles. Developing structured mentoring program and training both faculty and trainees in mentoring is recommended to improve the current practice of mentoring within the training programs. PMID:29416385
Electric and hybrid vehicle system R/D
NASA Technical Reports Server (NTRS)
Schwartz, H. J.
1980-01-01
The work being done to characterize the level of current propulsion technology through component testing is described. Important interactions between the battery and the propulsion system will be discussed. Component development work, involving traction motors, motor controllers and transmissions are described and current results are presented. Studies of advanced electric and hybrid propulsion system studies are summarized and the status of propulsion system development work supported by the project is described. A strategy for fostering joint industry/government projects for commercialization of propulsion components and systems is described briefly.
NASA Technical Reports Server (NTRS)
Keskinen, M. J.; Chaturvedi, P. K.; Ossakow, S. L.
1992-01-01
The 2D nonlinear evolution of the ionization-driven adiabatic auroral arc instability is studied. We find: (1) the adiabatic auroral arc instability can fully develop on time scales of tens to hundreds of seconds and on spatial scales of tens to hundreds of kilometers; (2) the evolution of this instability leads to nonlinear 'hook-shaped' conductivity structures: (3) this instability can lead to parallel current filamentation over a wide range of scale sizes; and (4) the k-spectra of the density, electric field, and parallel current develop into inverse power laws in agreement with satellite observations. Comparison with mesoscale auroral phenomenology and current filamentation structures is made.
ERIC Educational Resources Information Center
Hasibuan, Sarmadan
2013-01-01
In order to solve the weakness of current status of high school teachers' professional competency in Padangsidimpuan the researcher purposed this study to implement A Model of Continuing Professional Competency Development by using Information Communication Technology (ICT). This study was conducted by using a Research and Development (R&D).…
A short-pulse mode for the SPHINX LTD Z-pinch driver
NASA Astrophysics Data System (ADS)
D'Almeida, Thierry; Lassalle, Francis; Zucchini, Frederic; Loyen, Arnaud; Morell, Alain; Chuvatin, Alexander
2015-11-01
The SPHINX machine is a 6MA, 1 μs, LTD Z-pinch driver at CEA Gramat (France) and primarily used for studying radiation effects. Different power amplification concepts were examined in order to reduce the current rise time without modifying the generator discharge scheme, including the Dynamic Load Current Multiplier (DLCM) proposed by Chuvatin. A DLCM device, capable of shaping the current pulse without reducing the rise time, was developed at CEA. This device proved valuable for isentropic compression experiments in cylindrical geometry. Recently, we achieved a short pulse operation mode by inserting a vacuum closing switch between the DLCM and the load. The current rise time was reduced to ~300 ns. We explored the use of a reduced-height wire array for the Dynamic Flux Extruder in order to improve the wire array compression rate and increase the efficiency of the current transfer to the load. These developments are presented. Potential benefits of these developments for future Z pinch experiments are discussed.
Practices of Management Development: A Malaysian Case Study
ERIC Educational Resources Information Center
Law, Kian Aun
2008-01-01
This paper deals with a case study of Management Development (MD) practices at Malaysian Assurance Alliance (MAA). The aim of this research is to investigate how a large Malaysian insurance corporation developed and integrated MD initiatives with current organizational needs and tasks. Attempts were made to map and categorize the MD initiatives…
ERIC Educational Resources Information Center
Hernthaisong, Prasertsak; Sirisuthi, Chaiyuth; Wisetrinthong, Kanjana
2017-01-01
The research aimed to: 1) study the factors of a participative management system in learning environment management, 2) study the current situation, desirable outcomes, and further needs for developing a participative management system in learning management, 3) develop a working participative management system, and 4) assess the system's…
The Production of Figurative Language in Typically Developing Children and Williams Syndrome
ERIC Educational Resources Information Center
Naylor, Lauren; Van Herwegen, Jo
2012-01-01
The current study investigated the development of figurative language production, including different types of figurative expressions, during a fictional narrative in 20 typically developing (TD) children and 20 children with Williams syndrome (WS) aged 7-18 years old. In contrast to previous studies, developmental trajectories showed that (1) the…
ERIC Educational Resources Information Center
Eow, Yee Leng; Ali, Wan Zah bte Wan; Mahmud, Rosnaini bt.; Baki, Roselan
2010-01-01
Creativity is an important entity in developing human capital while computer games are the current generation's contemporary tool. This study focused on the teaching of computer games development in order to enhance the creative perception of secondary school children. The study applied randomised subjects, with control group experimental design,…
Dickson, Catherine; Arnason, Trevor; Friedman, Dara Spatz; Metz, Gila; Grimshaw, Jeremy M
2017-11-01
Clinical guidelines help ensure consistent care informed by current evidence. As shifts in antimicrobial resistance continue to influence first-line treatment, up-to-date guidelines are important for preventing treatment failure. A guideline's development process will influence its recommendations and users' trust. To assess the quality of current gonorrhoea guidelines' development processes. Multiple databases. Original and current English-language guidelines targeting health professionals and containing treatment recommendations for uncomplicated gonorrhoea in the general adult population. Two appraisers assessed the guidelines independently using the Appraisal of Guidelines for Research and Evaluation II (AGREE II) tool. Scores were combined as per the AGREE II users' manual. We identified 10 guidelines meeting the inclusion criteria. The quality of the gonorrhoea treatment guidelines varied. Most scored poorly on Rigour of Development ; information on the evidence review process and methods for formulating recommendations was often missing. The WHO Guidelines for the Treatment of Neisseria gonorrhoeae and UK National Guideline for the Management of Gonorrhoea in Adults scored the highest on Rigour of Development . Methods to address conflicts of interest were often not described in the materials reviewed. Implementation of recommendations was often not addressed. By limiting our study to English-language guidelines, a small number of guidelines we identified were excluded. Our analysis was limited to either published or online materials that were readily available to users. We could not differentiate between items addressed in the development process but not documented from items that were not addressed. Gonorrhoea treatment guidelines may slow antimicrobial resistance. Many current guidelines are not in line with the current guideline development best practices; this might undermine the perceived trustworthiness of guidelines. By identifying current limitations, this study can help improve the quality of future guidelines. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.
ERIC Educational Resources Information Center
Ayoubi, Rami M.; Massoud, Hiba
2012-01-01
Purpose: The main aim of the current study is to explore and model the major obstacles that UK universities encounter when developing international partnerships with overseas universities. Design/methodology/approach: Focusing on the obstacles to developing international partnerships, the study results are developed from 24 interviews with senior…
Collection Development Project.
ERIC Educational Resources Information Center
Nuby, Mary
Undertaken to provide data on the current status of collection development in selected academic libraries, this study also analyzed the structure of the collection development function at Chicago Academic Library Council (CALC) institutions and outlined a formal collection development policy for Chicago State University's Douglas Library.…
Postgraduate Studies in Librarianship and Information Science in Spain
ERIC Educational Resources Information Center
Muñoz-Cañavate, Antonio; Larios-Suárez, Verónica
2017-01-01
This paper reviews the history and current situation of postgraduate studies in Librarianship and Information Science (LIS) at the university level in Spain before and after the development of the Bologna Process's European Higher Education Area (EHEA). It contextualizes the historical development of these studies, describing how official…
The Motivation to Serve Others: Exploring Relations to Career Development
ERIC Educational Resources Information Center
Duffy, Ryan D.; Raque-Bogdan, Trisha L.
2010-01-01
The current study explored the relation between service motivation, or the desire to serve others through one's future career, and vocational outcomes across two studies. In the first study, using a sample of 225 undergraduate students, an instrument was developed to measure service motivation that demonstrated convergent and discriminant…
Patterns of Entrepreneurial Career Development: An Optimal Matching Analysis Approach
ERIC Educational Resources Information Center
Zacher, Hannes; Biemann, Torsten; Gielnik, Michael M.; Frese, Michael
2012-01-01
Longitudinal studies of entrepreneurial career development are rare, and current knowledge of self-employment patterns and their relationships with individual difference characteristics is limited. In this study, the authors analyzed employment data from a subsample of 514 participants from the German Socio-Economic Panel study (1984-2008).…
Edelstein, Barry A.; Heisel, Marnin J.; McKee, Deborah R.; Martin, Ronald R.; Koven, Lesley P.; Duberstein, Paul R.; Britton, Peter C.
2009-01-01
Purpose: The purposes of these studies were to develop and initially evaluate the psychometric properties of the Reasons for Living Scale—Older Adult version (RFL-OA), an older adults version of a measure designed to assess reasons for living among individuals at risk for suicide. Design and Methods: Two studies are reported. Study 1 involved instrument development with 106 community-dwelling older adults, and initial psychometric evaluation with a second sample of 119 community-dwelling older adults. Study 2 evaluated the psychometric properties of the RFL-OA in a clinical sample. One hundred eighty-one mental health patients 50 years or older completed the RFL-OA and measures of depression, suicide ideation at the current time and at the worst point in one's life, and current mental status and physical functioning. Results: Strong psychometric properties were demonstrated for the RFL-OA, with high internal consistency (Cronbach's alpha coefficient). Convergent validity was evidenced by negative associations among RFL-OA scores and measures of depression and suicide ideation. RFL-OA scores predicted current and worst-episode suicide ideation above and beyond current depression. Discriminant validity was evidenced with measures of current mental status and physical functioning. Criterion-related validity was also demonstrated with respect to lifetime history of suicidal behavior. Implications: These findings provide preliminary support for the validity and reliability of the RFL-OA. The findings also support the potential value of attending to reasons for living during clinical treatment with depressed older adults and others at risk for suicide. PMID:19546114
The impact of poverty on the development of brain networks
Lipina, Sebastián J.; Posner, Michael I.
2012-01-01
Although the study of brain development in non-human animals is an old one, recent imaging methods have allowed non-invasive studies of the gray and white matter of the human brain over the lifespan. Classic animal studies show clearly that impoverished environments reduce cortical gray matter in relation to complex environments and cognitive and imaging studies in humans suggest which networks may be most influenced by poverty. Studies have been clear in showing the plasticity of many brain systems, but whether sensitivity to learning differs over the lifespan and for which networks is still unclear. A major task for current research is a successful integration of these methods to understand how development and learning shape the neural networks underlying achievements in literacy, numeracy, and attention. This paper seeks to foster further integration by reviewing the current state of knowledge relating brain changes to behavior and indicating possible future directions. PMID:22912613
Space station contamination control study: Internal combustion, phase 1
NASA Technical Reports Server (NTRS)
Ruggeri, Robert T.
1987-01-01
Contamination inside Space Station modules was studied to determine the best methods of controlling contamination. The work was conducted in five tasks that identified existing contamination control requirements, analyzed contamination levels, developed outgassing specification for materials, wrote a contamination control plan, and evaluated current materials of offgassing tests used by NASA. It is concluded that current contamination control methods can be made to function on the Space Station for up to 1000 days, but that current methods are deficient for periods longer than about 1000 days.
Formation of current singularity in a topologically constrained plasma
DOE Office of Scientific and Technical Information (OSTI.GOV)
Zhou, Yao; Huang, Yi-Min; Qin, Hong
2016-02-01
Recently a variational integrator for ideal magnetohydrodynamics in Lagrangian labeling has been developed. Its built-in frozen-in equation makes it optimal for studying current sheet formation. We use this scheme to study the Hahm-Kulsrud-Taylor problem, which considers the response of a 2D plasma magnetized by a sheared field under sinusoidal boundary forcing. We obtain an equilibrium solution that preserves the magnetic topology of the initial field exactly, with a fluid mapping that is non-differentiable. Unlike previous studies that examine the current density output, we identify a singular current sheet from the fluid mapping. These results are benchmarked with a constrained Grad-Shafranovmore » solver. The same signature of current singularity can be found in other cases with more complex magnetic topologies.« less
Integrating Professional Development across the Curriculum: An Effectiveness Study
ERIC Educational Resources Information Center
Ciarocco, Natalie J.; Dinella, Lisa M.; Hatchard, Christine J.; Valosin, Jayde
2016-01-01
The current study empirically tested the effectiveness of a modular approach to integrating professional development across an undergraduate psychology curriculum. Researchers conducted a two-group, between-subjects experiment on 269 undergraduate psychology students assessing perceptions of professional preparedness and learning. Analysis…
Laboratory study - laboratory testing of bridge deck mixes
DOT National Transportation Integrated Search
2003-03-01
The purpose of this investigation was to develop bridge deck mixes that will improve field performance and minimize cracking potential compared to MoDOT's current (B-2) bridge deck mix design. The mix designs developed in this study were tested and c...
ERIC Educational Resources Information Center
McKim, Aaron J.; Velez, Jonathan J.
2017-01-01
To extend current understanding of school-based agriculture teacher development, this study explored the relationship between teacher development experiences and the self-efficacy of early career agriculture teachers. Three teacher development experiences were of interest: (a) preservice coursework, (b) student teaching, and (c) professional…
Prevention of epilepsy: Should we be avoiding clinical trials?
Klein, Pavel; Tyrlikova, Ivana
2017-07-01
Epilepsy prevention is one of the great unmet needs in epilepsy. Approximately 15% of all epilepsy is caused by an acute acquired CNS insult such as traumatic brain injury (TBI), stroke or encephalitis. There is a latent period between the insult and epilepsy onset that presents an opportunity to intervene with preventive treatment that is unique in neurology. Yet no phase 3 epilepsy prevention studies, and only 2 phase 2 studies have been initiated in the last 16years. Current prevailing opinion is that the research community is not ready for clinical preventive epilepsy studies, and that animal models should first be refined and biomarkers of epileptogenesis and of epilepsy discovered before clinical studies are embarked upon. We review data to suggest that there is basis to do epilepsy prevention studies now with the current knowledge and available drugs, and that those studies are feasible with currently available tools. We suggest that a different approach is needed from the past in order to maximize chances of success, minimize the cost, and set up platform for future preventive treatment development. That approach should include close coordination of preclinical and clinical development programs in a combined PTE prevention strategy, consideration of polytherapy, and simultaneous, combined clinical development of preventive treatment and of biomarker discovery. We argue that the currently favored approach of eschewing clinical studies until biomarkers are available will delay the discovery of epilepsy prevention treatment by at least 10 years and significantly increase the cost of such discovery. Copyright © 2017 Elsevier Inc. All rights reserved.
Energy Analysis Center. His current research focuses on support and development of U.S. offshore wind transportation and logistics studies to develop investment recommendations for DOE. Tyler's experience includes
Stabilizing effect of helical current drive on tearing modes
NASA Astrophysics Data System (ADS)
Yuan, Y.; Lu, X. Q.; Dong, J. Q.; Gong, X. Y.; Zhang, R. B.
2018-01-01
The effect of helical driven current on the m = 2/n = 1 tearing mode is studied numerically in a cylindrical geometry using the method of reduced magneto-hydro-dynamic simulation. The results show that the local persistent helical current drive from the beginning time can be applied to control the tearing modes, and will cause a rebound effect called flip instability when the driven current reaches a certain value. The current intensity threshold value for the occurrence of flip instability is about 0.00087I0. The method of controlling the development of tearing mode with comparative economy is given. If the local helical driven current is discontinuous, the magnetic island can be controlled within a certain range, and then, the tearing modes stop growing; thus, the flip instability can be avoided. We also find that the flip instability will become impatient with delay injection of the driven current because the high order harmonics have been developed in the original O-point. The tearing mode instability can be controlled by using the electron cyclotron current drive to reduce the gradient of the current intensity on the rational surfaces.
DOT National Transportation Integrated Search
2014-04-01
The purpose of the current study was to further develop and refine the prototype Enhanced Rear Signaling (ERS) : system that was developed during the previous Phase III effort. Expanded development efforts for the ERS system : included modification o...
Review of operations in the Virginia Department of Transportation's project development process.
DOT National Transportation Integrated Search
2007-01-01
The Virginia Department of Transportation's (VDOT's) project development process (PDP) directs how construction projects are developed. The purpose of this study was to evaluate the manner in which operations is currently considered throughout the PD...
Technical and Economic Evaluation of Advanced Air Cargo Systems
NASA Technical Reports Server (NTRS)
Whitehead, A. H., Jr.
1978-01-01
The current air cargo environment and the relevance of advanced technology aircraft in enhancing the efficiency of the 1990 air cargo system are discussed. NASA preliminary design studies are shown to indicate significant potential gains in aircraft efficiency and operational economics for future freighter concepts. Required research and technology elements are outlined to develop a better base for evaluating advanced design concepts. Current studies of the market operation are reviewed which will develop design criteria for a future dedicated cargo transport. Design features desirable in an all-freighter design are reviewed. NASA-sponsored studies of large, distributed-load freighters are reviewed and these designs are compared to current wide-body aircraft. These concepts vary in gross takeoff weight from 0.5 Gg (one million lbs.) to 1.5 Gg (three million lbs.) and are found to exhibit economic advantages over conventional design concepts.
Molecular aspects of development and regulation of endometriosis
2014-01-01
Endometriosis is a common and painful condition affecting women of reproductive age. While the underlying pathophysiology is still largely unknown, much advancement has been made in understanding the progression of the disease. In recent years, a great deal of research has focused on non-invasive diagnostic tools, such as biomarkers, as well as identification of potential therapeutic targets. In this article, we will review the etiology and cellular mechanisms associated with endometriosis as well as the current diagnostic tools and therapies. We will then discuss the more recent genomic and proteomic studies and how these data may guide development of novel diagnostics and therapeutics. The current diagnostic tools are invasive and current therapies primarily treat the symptoms of endometriosis. Optimally, the advancement of “-omic” data will facilitate the development of non-invasive diagnostic biomarkers as well as therapeutics that target the pathophysiology of the disease and halt, or even reverse, progression. However, the amount of data generated by these types of studies is vast and bioinformatics analysis, such as we present here, will be critical to identification of appropriate targets for further study. PMID:24927773
Development and the environmental impact analysis of tidal current energy turbines in China
NASA Astrophysics Data System (ADS)
Liu, Yuxin; Ma, Changlei; Jiang, Bo
2018-02-01
Chinese government pays more attentions to renewable energies (RE) in the context of increasing energy demand and climate change problems. As a promising RE, the utilization of marine renewable energy (MRE) is engaging in the world, including the wave energy and tidal current energy mainly. At the same time, the tidal current energy resources in China are abundant. Thus, the utilization of tidal current energy becomes an inevitable choice for China to meet the challenge of global climate change. The Renewable Energy Law (amendment) and “Twelfth Five-Year” Plan of Renewable Energy Development (2011-2015) were released in recent years in China, the tidal current energy are successfully implemented in China, including the R&D and pilot projects. After the summary of the status of tidal current energy converters in recent years in China, especially the devices being in the open sea test. The environmental impact study in China is also introduced in order to offer reference for the environmental impact assessment of tidal current power generation.
Possibilities and limitations of current stereo-endoscopy.
Mueller-Richter, U D A; Limberger, A; Weber, P; Ruprecht, K W; Spitzer, W; Schilling, M
2004-06-01
Stereo-endoscopy has become a commonly used technology. In many comparative studies striking advantages of stereo-endoscopy over two-dimensional presentation could not be proven. To show the potential and fields for further improvement of this technology is the aim of this article. The physiological basis of three-dimensional vision limitations of current stereo-endoscopes is discussed and fields for further research are indicated. New developments in spatial picture acquisition and spatial picture presentation are discussed. Current limitations of stereo-endoscopy that prevent a better ranking in comparative studies with two-dimensional presentation are mainly based on insufficient picture acquisition. Devices for three-dimensional picture presentation are at a more advanced developmental stage than devices for three-dimensional picture acquisition. Further research should emphasize the development of new devices for three-dimensional picture acquisition.
NASA Astrophysics Data System (ADS)
Jewulski, J. R.; Osif, T. L.; Remick, R. J.
1990-12-01
The purpose of this program was to survey the field of solid-state proton conductors (SSPC), identify conductors that could be used to develop solid-state fuel cells suitable for use with coal derived fuel gases, and begin the experimental research required for the development of these fuel cells. This document covers the following topics: the history of developments and current status of the SSPC, including a review of proton conducting electrolyte structures, the current status of the medium temperature SSPC development, electrodes for moderate temperature (SSPC) fuel cell, basic material and measurement techniques applicable for SSPC development, modeling, and optimization studies. Correlation and optimization studies are described which include correlation studies on proton conduction and oxide cathode optimization for the SSPC fuel cell. Experiments with the SSPC fuel cells are presented which include the fabrication of the electrolyte disks, apparatus for conducting measurements, the strontium-cerium based electrolyte, the barium-cerium based electrolyte with solid foil electrodes, the barium-cerium based electrolyte with porous electrodes, and conduction mechanisms.
ERIC Educational Resources Information Center
Ma, Ning; Xin, Shuang; Du, Jia-Yuan
2018-01-01
Personalized learning based on learning analytics has become increasingly important for teachers' development via providing adaptive contents and strategies for teachers by identifying their questions and needs. Currently, most studies on teachers' professional development focus on pre-service teachers, and studies on teachers' personalized…
ERIC Educational Resources Information Center
McCullough, Sabrina D.
2016-01-01
This action research study investigated the change in professional development model in the acquisition of content knowledge for fourth-grade math teachers. The current professional development atmosphere is a traditional "sit and get" opportunity. However, research offers that teachers should be active participants in their learning.…
The Effect of Strengths Awareness and Development on the Self-Efficacy of Teachers
ERIC Educational Resources Information Center
Griffin, Lauren Elyse
2016-01-01
Increasing teacher efficacy poses challenges to educational leaders, highlighting the need for a study of the awareness and development of strengths related to teacher efficacy. The purpose of the current study was to examine the effect of the awareness and development of strengths on teachers' perceived self-efficacy, as well as to determine if…
The New Agent: A Qualitative Study to Strategically Adapt New Agent Professional Development
ERIC Educational Resources Information Center
Baker, Lauri M.; Hadley, Gregg
2014-01-01
The qualitative study reported here assessed the needs of agents related to new agent professional development to improve the current model. Agents who participated in new agent professional development within the last 5 years were selected to participate in focus groups to determine concerns and continued needs. Agents enjoyed networking and…
ERIC Educational Resources Information Center
Yamamoto, Yukiko; Enomoto, Naoko; Yamaguchi, Shinobu
2016-01-01
Reflecting the social and economic change, Japanese education has shifted to decentralization since the 1980s. With an increased autonomy and responsibility, the local government plays an important role to develop competent school leaders. This descriptive study employs case study approach to illustrate current status of leadership development at…
ERIC Educational Resources Information Center
Chin, Iris; Goodwin, Matthew S.; Vosoughi, Soroush; Roy, Deb; Naigles, Letitia R.
2018-01-01
Studies investigating the development of tense/aspect in children with developmental disorders have focused on production frequency and/or relied on short spontaneous speech samples. How children with developmental disorders use future forms/constructions is also unknown. The current study expands this literature by examining frequency,…
Parenting and Preschool Self-Regulation as Predictors of Social Emotional Competence in 1st Grade
ERIC Educational Resources Information Center
Russell, Beth S.; Lee, Jungeun Olivia; Spieker, Susan; Oxford, Monica L.
2016-01-01
The current longitudinal study used data from the National Institute of Child Health and Human Development (NICHD) Study of Early Child Care and Youth Development (SECCYD) to examine a model of development that emphasizes early caregiving environments as predictors of social emotional competence (including classroom competence). This path analysis…
The Writing Development of English Language Learners from Two Grades
ERIC Educational Resources Information Center
Zheng, Xun
2012-01-01
The current study is a qualitative case study that investigated the writing development of seven Chinese-speaking English language learners (ELLs) from kindergarten and 3rd-grade ESL classes in an elementary school in the Midwest and intended to discover the factors that affect students' English writing development in a one-year period. Guided by…
NASA Astrophysics Data System (ADS)
Harris, Daniel L.; Vila-Concejo, Ana; Webster, Jody M.
2014-10-01
Back-reef sand aprons are conspicuous and dynamic sedimentary features in coral reef systems. The development of these features influences the evolution and defines the maturity of coral reefs. However, the hydrodynamic processes that drive changes on sand aprons are poorly understood with only a few studies directly assessing sediment entrainment and transport. Current and wave conditions on a back-reef sand apron were measured during this study and a digital elevation model was developed through topographic and bathymetric surveying of the sand apron, reef flats and lagoon. The current and wave processes that may entrain and transport sediment were assessed using second order small amplitude (Stokes) wave theory and Shields equations. The morphodynamic interactions between current flow and geomorphology were also examined. The results showed that sediment transport occurs under modal hydrodynamic conditions with waves the main force entraining sediment rather than average currents. A morphodynamic relationship between current flow and geomorphology was also observed with current flow primarily towards the lagoon in shallow areas of the sand apron and deeper channel-like areas directing current off the sand apron towards the lagoon or the reef crest. These results show that the short-term mutual interaction of hydrodynamics and geomorphology in coral reefs can result in morphodynamic equilibrium.
ERIC Educational Resources Information Center
Stewart, Paul; Reihman, Jacqueline; Lonky, Edward; Darvill, Thomas; Pagano, James
2004-01-01
In the current paper we describe the methodology and results of the Oswego study, in light of D.V. Cicchetti, A.S. Kaufman, and S.S. Sparrow's (this issue) criticisms regarding the validity of the human health/behavioral claims in the PCB literature. The Oswego project began as a replication of the Lake Michigan Maternal Infant Cohort study.…
Shape design and CFD analysis on a 1MW-class horizontal axis tidal current turbine blade
NASA Astrophysics Data System (ADS)
Singh, P. M.; Choi, Y. D.
2013-12-01
This study aims to develop a 1MW-class horizontal axis tidal current turbine rotor blade which can be applied near the southwest island regions of South Korea. On the basis of actual tidal current conditions of southern region of Korea, configuration design of 1MW class turbine rotor blade is carried out by BEMT (Blade element momentum theory). The hydrodynamic performance including the lift and drag forces, is conducted with the variation of the angle of attack using an open source code of X-Foil. The purpose of the study is to study the shape of the hydrofoil used and how it affects the performance of the turbine. After a thorough study of many airfoils, a new hydrofoil is developed using the S814 and DU-91-W2- 250 airfoils, which show good performance for rough conditions. A combination of the upper and lower surface of the two hydrofoils is tested. Three dimensional models were developed and the optimized blade geometry is used for CFD (Computational Fluid Dynamics) analysis with hexahedral numerical grids. Power coefficient, pressure coefficient and velocity distributions are investigated according to Tip Speed Ratio by CFD analysis.
HOLDING TIME STUDY FOR FECALS/SALMONELLA & CONNECTING LANGUAGE FOR 503 REGULATIONS
Current federal regulations required monitoring for fecal coliforms or Salmonella in biosolids destined for land application. Methods used for analysis of fecal coliforms and Salmonella have been developed and are currently in use for quantification of these organisms. Recently c...
Research Models in Developmental Behavioral Toxicology.
ERIC Educational Resources Information Center
Dietrich, Kim N.; Pearson, Douglas T.
Developmental models currently used by child behavioral toxicologists and teratologists are inadequate to address current issues in these fields. Both child behavioral teratology and toxicology scientifically study the impact of exposure to toxic agents on behavior development: teratology focuses on prenatal exposure and postnatal behavior…
Mentoring as Professional Development: "Growth for Both" Mentor and Mentee
ERIC Educational Resources Information Center
Hudson, Peter
2013-01-01
Teachers need professional development to keep current with teaching practices, although costs for extensive professional development can be prohibitive across an education system. Mentoring provides one way for embedding cost-effective professional development. This mixed-method study includes surveying mentor teachers ("n" = 101) on a…
Biomarkers of tolerance: searching for the hidden phenotype.
Perucha, Esperanza; Rebollo-Mesa, Irene; Sagoo, Pervinder; Hernandez-Fuentes, Maria P
2011-08-01
Induction of transplantation tolerance remains the ideal long-term clinical and logistic solution to the current challenges facing the management of renal allograft recipients. In this review, we describe the recent studies and advances made in identifying biomarkers of renal transplant tolerance, from study inceptions, to the lessons learned and their implications for current and future studies with the same goal. With the age of biomarker discovery entering a new dimension of high-throughput technologies, here we also review the current approaches, developments, and pitfalls faced in the subsequent statistical analysis required to identify valid biomarker candidates.
Study on Control of Security and Storage of Holdings: A RAMP Study with Guidelines.
ERIC Educational Resources Information Center
Thomas, D. L.
Intended to assist developing countries in the essential task of preserving historical records and, therefore, deliberately oriented towards economy and a low level of technology, this study provides an outline of currently accepted standards that archivists in developing countries, especially those in tropical areas, can apply to their own…
Decision-Making Casebook for Business and Economics.
ERIC Educational Resources Information Center
Tedesco, Paul H., Ed.; And Others
These teacher developed case studies taken from the business world are presented to help secondary students develop an understanding of economics and of the decision-making process. The studies describe real business situations. All historical and current facts are provided for each of the seven case studies. In the first case, students debate…
NASA Technical Reports Server (NTRS)
Sireli, Yesim; Kauffmann, Paul; Gupta, Surabhi; Kachroo, Pushkin
2002-01-01
In this study, current characteristics and future developments of Intelligent Transportation Systems (ITS) in the automobile and trucking industry are investigated to identify the possible implications of such systems for General Aviation (GA) cockpit weather systems. First, ITS are explained based on tracing their historical development in various countries. Then, current systems and the enabling communication technologies are discussed. Finally, a market analysis for GA is included.
ERIC Educational Resources Information Center
Chief of Naval Education and Training Support, Pensacola, FL.
This individualized learning module on the relationships of current, voltage, and resistance is one in a series of modules for a course in basic electricity and electronics. The course is one of a number of military-developed curriculum packages selected for adaptaticn to vocational instructional and curriculum development in a civilian setting.…
Leveling the Playing Field: China’s Development of Advanced Energy Weapons
2012-05-02
02-05-2012 2. REPORT TYPE Master of Military Studies Research Paper 3. DATES COVERED (From - To) September 2011 - April 2012 5a. CONTRACT NUMBER...weapons in a surprise attack scenario to counter superior U.S. capabilities and technology. This paper will update and review current and developing...utilizing these weapons in a surprise attack scenario to counter superior U.S. capabilities and technology. This paper will update and review current
Methods for the Study of Gonadal Development.
Piprek, Rafal P
2016-01-01
Current knowledge on gonadal development and sex determination is the product of many decades of research involving a variety of scientific methods from different biological disciplines such as histology, genetics, biochemistry, and molecular biology. The earliest embryological investigations, followed by the invention of microscopy and staining methods, were based on histological examinations. The most robust development of histological staining techniques occurred in the second half of the nineteenth century and resulted in structural descriptions of gonadogenesis. These first studies on gonadal development were conducted on domesticated animals; however, currently the mouse is the most extensively studied species. The next key point in the study of gonadogenesis was the advancement of methods allowing for the in vitro culture of fetal gonads. For instance, this led to the description of the origin of cell lines forming the gonads. Protein detection using antibodies and immunolabeling methods and the use of reporter genes were also invaluable for developmental studies, enabling the visualization of the formation of gonadal structure. Recently, genetic and molecular biology techniques, especially gene expression analysis, have revolutionized studies on gonadogenesis and have provided insight into the molecular mechanisms that govern this process. The successive invention of new methods is reflected in the progress of research on gonadal development.
Dominant heterosexual sexual scripts in emerging adulthood: conceptualization and measurement.
Sakaluk, John K; Todd, Leah M; Milhausen, Robin; Lachowsky, Nathan J
2014-01-01
Sexual script research (Simon & Gagnon 1969 , 1986 ) bourgeoned following Simon and Gagnon's groundbreaking work. Empirical measurement of sexual script adherence has been limited, however, as no measures exist that have undergone rigorous development and validation. We conducted three studies to examine current dominant sexual scripts of heterosexual adults and to develop a measure of endorsement of these scripts. In Study 1, we conducted three focus groups of men ( n = 19) and four of women ( n = 20) to discuss the current scripts governing sexual behavior. Results supported scripts for sex drive, physical and emotional sex, sexual performance, initiation and gatekeeping, and evaluation of sexual others. In Study 2, we used these qualitative findings to develop a measure of script endorsement, the Sexual Script Scale. Factor analysis of data from 721 participants revealed six interrelated factors demonstrating initial construct validity. In Study 3, confirmatory factor analysis of a separate sample of 289 participants supported the model from Study 2, and evidence of factorial invariance and test-retest reliability was obtained. This article presents the results of these studies, documenting the process of scale development from formative research through to confirmatory testing, and suggests future directions for the continued development of sexual scripting theory.
ERIC Educational Resources Information Center
Bierema, Andrea M.-K.; Schwartz, Renee S.; Gill, Sharon A.
2017-01-01
Recent calls for reform in education recommend science curricula to be based on central ideas instead of a larger number of topics and for alignment between current scientific research and curricula. Because alignment is rarely studied, especially for central ideas, we developed a methodology to discover the extent of alignment between primary…
Has molecular imaging delivered to drug development?
NASA Astrophysics Data System (ADS)
Murphy, Philip S.; Patel, Neel; McCarthy, Timothy J.
2017-10-01
Pharmaceutical research and development requires a systematic interrogation of a candidate molecule through clinical studies. To ensure resources are spent on only the most promising molecules, early clinical studies must understand fundamental attributes of the drug candidate, including exposure at the target site, target binding and pharmacological response in disease. Molecular imaging has the potential to quantitatively characterize these properties in small, efficient clinical studies. Specific benefits of molecular imaging in this setting (compared to blood and tissue sampling) include non-invasiveness and the ability to survey the whole body temporally. These methods have been adopted primarily for neuroscience drug development, catalysed by the inability to access the brain compartment by other means. If we believe molecular imaging is a technology platform able to underpin clinical drug development, why is it not adopted further to enable earlier decisions? This article considers current drug development needs, progress towards integration of molecular imaging into studies, current impediments and proposed models to broaden use and increase impact. This article is part of the themed issue 'Challenges for chemistry in molecular imaging'.
Lower-Dark-Current, Higher-Blue-Response CMOS Imagers
NASA Technical Reports Server (NTRS)
Pain, Bedabrata; Cunningham, Thomas; Hancock, Bruce
2008-01-01
Several improved designs for complementary metal oxide/semiconductor (CMOS) integrated-circuit image detectors have been developed, primarily to reduce dark currents (leakage currents) and secondarily to increase responses to blue light and increase signal-handling capacities, relative to those of prior CMOS imagers. The main conclusion that can be drawn from a study of the causes of dark currents in prior CMOS imagers is that dark currents could be reduced by relocating p/n junctions away from Si/SiO2 interfaces. In addition to reflecting this conclusion, the improved designs include several other features to counteract dark-current mechanisms and enhance performance.
Smoking and risk of treatment-induced neutralizing antibodies to interferon β-1a.
Hedström, Anna Karin; Ryner, Malin; Fink, Katarina; Fogdell-Hahn, Anna; Alfredsson, Lars; Olsson, Tomas; Hillert, Jan
2014-04-01
Neutralizing antibodies (NAbs) to interferon β (IFNβ) products that develop during treatment are associated with a loss of clinical efficacy. The aim of this study was to investigate the influence of smoking habits on the risk of developing NAbs to IFNβ, in the treatment of multiple sclerosis (MS). This report is based on 695 MS patients treated with IFNβ-1a, included in two Swedish case-control studies that collected information on smoking habits. Using logistic regression, the development of NAbs to IFNβ-1a among current smokers was compared with that of non-smokers, by calculating the odds ratio (OR) with a 95% confidence interval (CI). Current smokers showed an increased risk of developing NAbs to IFNβ-1a, compared with non-smokers (OR 1.9; 95% CI 1.3-2.8; p = 0.002). There were no gender differences. We observed no association between past smoking and the risk of developing NAbs to IFNβ-1a. The finding that current smokers have an increased risk of developing NAbs to IFNβ-1a has implications, both for the practical care and the treatment of MS; it also provides an interesting perspective of the lungs as an immune-reactive organ, reacting upon irritation.
NASA Technical Reports Server (NTRS)
Bihrle, W., Jr.
1976-01-01
A correlation study was conducted to determine the ability of current analytical spin prediction techniques to predict the flight motions of a current fighter airplane configuration during the spin entry, the developed spin, and the spin recovery motions. The airplane math model used aerodynamics measured on an exact replica of the flight test model using conventional static and forced-oscillation wind-tunnel test techniques and a recently developed rotation-balance test apparatus capable of measuring aerodynamics under steady spinning conditions. An attempt was made to predict the flight motions measured during stall/spin flight testing of an unpowered, radio-controlled model designed to be a 1/10 scale, dynamically-scaled model of a current fighter configuration. Comparison of the predicted and measured flight motions show that while the post-stall and spin entry motions were not well-predicted, the developed spinning motion (a steady flat spin) and the initial phases of the spin recovery motion are reasonably well predicted.
Flanagan, Sarah E.; De Franco, Elisa; Lango Allen, Hana; Zerah, Michele; Abdul-Rasoul, Majedah M.; Edge, Julie A.; Stewart, Helen; Alamiri, Elham; Hussain, Khalid; Wallis, Sam; de Vries, Liat; Rubio-Cabezas, Oscar; Houghton, Jayne A.L.; Edghill, Emma L.; Patch, Ann-Marie; Ellard, Sian; Hattersley, Andrew T.
2014-01-01
Summary Understanding transcriptional regulation of pancreatic development is required to advance current efforts in developing beta cell replacement therapies for patients with diabetes. Current knowledge of key transcriptional regulators has predominantly come from mouse studies, with rare, naturally occurring mutations establishing their relevance in man. This study used a combination of homozygosity analysis and Sanger sequencing in 37 consanguineous patients with permanent neonatal diabetes to search for homozygous mutations in 29 transcription factor genes important for murine pancreatic development. We identified homozygous mutations in 7 different genes in 11 unrelated patients and show that NKX2-2 and MNX1 are etiological genes for neonatal diabetes, thus confirming their key role in development of the human pancreas. The similar phenotype of the patients with recessive mutations and mice with inactivation of a transcription factor gene support there being common steps critical for pancreatic development and validate the use of rodent models for beta cell development. PMID:24411943
Propulsion Study for Small Transport Aircraft Technology (STAT)
NASA Technical Reports Server (NTRS)
Gill, J. C.; Earle, R. V.; Staton, D. V.; Stolp, P. C.; Huelster, D. S.; Zolezzi, B. A.
1980-01-01
Propulsion requirements were determined for 0.5 and 0.7 Mach aircraft. Sensitivity studies were conducted on both these aircraft to determine parametrically the influence of propulsion characteristics on aircraft size and direct operating cost (DOC). Candidate technology elements and design features were identified and parametric studies conducted to select the STAT advanced engine cycle. Trade off studies were conducted to determine those advanced technologies and design features that would offer a reduction in DOC for operation of the STAT engines. These features were incorporated in the two STAT engines. A benefit assessment was conducted comparing the STAT engines to current technology engines of the same power and to 1985 derivatives of the current technology engines. Research and development programs were recommended as part of an overall technology development plan to ensure that full commercial development of the STAT engines could be initiated in 1988.
Exploring the ring current of carbon nanotubes by first-principles calculations.
Ren, Pengju; Zheng, Anmin; Xiao, Jianping; Pan, Xiulian; Bao, Xinhe
2015-02-01
Ring current is a fundamental concept to understand the nuclear magnetic resonance (NMR) properties and aromaticity for conjugated systems, such as carbon nanotubes (CNTs). Employing the recently developed gauge including projector augmented wave (GIPAW) method, we studied the ring currents of CNTs systematically and visualized their distribution. The ring current patterns are determined by the semiconducting or metallic properties of CNTs. The discrepancy is mainly caused by the axial component of external magnetic fields, whereas the radial component induced ring currents are almost independent of the electronic structures of CNTs, where the intensities of the ring currents are linearly related to the diameters of the CNTs. Although the ring currents induced by the radial component are more intense than those by the axial component, only the latter determines the overall NMR responses and aromaticity of the CNTs as well. Furthermore, the semiconducting CNTs are more aromatic than their metallic counterparts due to the existence of delocalized ring currents on the semiconducting CNTs. These fundamental features are of vital importance for the development of CNT-based nanoelectronics and applications in magnetic fields.
Exploring the ring current of carbon nanotubes by first-principles calculations
Ren, Pengju; Zheng, Anmin; Xiao, Jianping; Pan, Xiulian
2015-01-01
Ring current is a fundamental concept to understand the nuclear magnetic resonance (NMR) properties and aromaticity for conjugated systems, such as carbon nanotubes (CNTs). Employing the recently developed gauge including projector augmented wave (GIPAW) method, we studied the ring currents of CNTs systematically and visualized their distribution. The ring current patterns are determined by the semiconducting or metallic properties of CNTs. The discrepancy is mainly caused by the axial component of external magnetic fields, whereas the radial component induced ring currents are almost independent of the electronic structures of CNTs, where the intensities of the ring currents are linearly related to the diameters of the CNTs. Although the ring currents induced by the radial component are more intense than those by the axial component, only the latter determines the overall NMR responses and aromaticity of the CNTs as well. Furthermore, the semiconducting CNTs are more aromatic than their metallic counterparts due to the existence of delocalized ring currents on the semiconducting CNTs. These fundamental features are of vital importance for the development of CNT-based nanoelectronics and applications in magnetic fields. PMID:29560175
National Plan for Graduate Studies.
ERIC Educational Resources Information Center
Ministry of Education and Culture, Brasilia (Brazil).
The Brazilian National Plan for Graduate Studies aims at achieving a combination of training activities at the graduate level to be developed at the various institutions of higher education and research. The current situation is reviewed in terms of stabilization, performance, and development problems. Objectives and general directives include:…
Sustained Attention and Social Competence in Typically Developing Preschool-Aged Children
ERIC Educational Resources Information Center
Murphy, Laura M. Bennett; Laurie-Rose, Cynthia; Brinkman, Tara M.; McNamara, Kelly A.
2007-01-01
The current study examines the relationship between sustained attention and social competence in preschool children. While studies demonstrate that children with attention deficit hyperactivity disorder (ADHD) exhibit poor social competence, less is known about typically developing children. Since children with ADHD have associated behavior…
Seeking a Multi-Construct Model of Morality
ERIC Educational Resources Information Center
McDaniel, Brenda L.; Grice, James W.; Eason, E. Allen
2010-01-01
The present study explored a multi-construct model of moral development. Variables commonly seen in the moral development literature, such as family interactions, spiritual life, ascription to various sources of moral authority, empathy, shame, guilt and moral judgement competence, were investigated. Results from the current study support previous…
How current ginning processes affect fiber length uniformity index
USDA-ARS?s Scientific Manuscript database
There is a need to develop cotton ginning methods that improve fiber characteristics that are compatible with the newer and more efficient spinning technologies. A literature search produced recent studies that described how current ginning processes affect HVI fiber length uniformity index. Resul...
Capacitive detection of micromotions: Monitoring ballistics of a developing avian embryo
NASA Astrophysics Data System (ADS)
Szymanski, Jan A.; Pawlak, Krzysztof; Wasowicz, Pawel; Moscicki, Jozef K.
2002-09-01
An instrument for noninvasive monitoring of very weak biomechanical activities of small living organisms is described. The construction is sufficiently flexible to permit a range of studies including developing embryos of oviparous animals, pests that live in loose materials and timber, and insects that develop in cocoons. Motions are detected by monitoring a current generated by the fluctuating position of the object-loaded electrode of a capacitive sensor. To maximize the signal, oscillations of the electrode are mechanically enhanced and the current is amplified and filtered by a two-stage signal amplifier and a bank of six active Butterworth filters. The device is optimized to ballistocardiography of hen embryos. The sensitivity achieved makes possible quantitative studies of heart activity of 7-day-old embryos.
Forcing and variability of nonstationary rip currents
Long, Joseph W.; H.T. Özkan-Haller,
2016-01-01
Surface wave transformation and the resulting nearshore circulation along a section of coast with strong alongshore bathymetric gradients outside the surf zone are modeled for a consecutive 4 week time period. The modeled hydrodynamics are compared to in situ measurements of waves and currents collected during the Nearshore Canyon Experiment and indicate that for the entire range of observed conditions, the model performance is similar to other studies along this stretch of coast. Strong alongshore wave height gradients generate rip currents that are observed by remote sensing data and predicted qualitatively well by the numerical model. Previous studies at this site have used idealized scenarios to link the rip current locations to undulations in the offshore bathymetry but do not explain the dichotomy between permanent offshore bathymetric features and intermittent rip current development. Model results from the month‐long simulation are used to track the formation and location of rip currents using hourly statistics, and results show that the direction of the incoming wave energy strongly controls whether rip currents form. In particular, most of the offshore wave spectra were bimodal and we find that the ratio of energy contained in each mode dictates rip current development, and the alongshore rip current position is controlled by the incident wave period. Additionally, model simulations performed with and without updating the nearshore morphology yield no significant change in the accuracy of the predicted surf zone hydrodyanmics indicating that the large‐scale offshore features (e.g., submarine canyon) predominately control the nearshore wave‐circulation system.
An Air Force Guide to the System Specification.
1981-01-01
basis for sound management plans and decisions to initiate system full-scale development. Related topics include: current problems and questions...such current documents as AFR 800-2 and AFR 57-1. Key elements of coverage include the following: a. Levels of system engineering studies are...equipment and computer program elements of a system are acquired most directly acainst lower-level (configuration item) specifications. b. Current
Fundamental Study of Tank with MgB2 Level Sensor for Transportation of Liquid Hydrogen
NASA Astrophysics Data System (ADS)
Maekawa, Kazuma; Takeda, Minoru; Matsuno, Yu; Fujikawa, Shizuichi; Kuroda, Tsuneo; Kumakura, Hiroaki
We are currently developing an external-heating-type superconducting magnesium diboride (MgB2) level sensor for a liquid hydrogen (LH2) tank. The aim of this study is to investigate the measuring current dependence of the level-detecting characteristics of the MgB2 level sensor for LH2 under a static condition which has not yet been clarified. It was found that the linear correlation coefficient was 0.99 or more, indicating high linearity, regardless of the measuring current at heater inputs of 3 W and 6 W. Moreover, there was no effect of self-heating by the measuring current and it was found that a current of up to 100 mA can be used.
Optimizing romanian maritime coastline using mathematical model Litpack
NASA Astrophysics Data System (ADS)
Anton, I. A.; Panaitescu, M.; Panaitescu, F. V.
2017-08-01
There are many methods and tools to study shoreline change in coastal engineering. LITPACK is a numerical model included in MIKE software developed by DHI (Danish Hydraulic Institute). With this matehematical model we can simulate coastline evolution and profile along beach. Research and methodology: the paper contents location of the study area, the current status of Midia-Mangalia shoreline, protection objectives, the changes of shoreline after having protected constructions. In this paper are presented numerical and graphycal results obtained with this model for studying the romanian maritime coastline in area MIDIA-MANGALIA: non-cohesive sediment transport, long-shore current and littoral drift, coastline evolution, crossshore profile evolution, the development of the coastline position in time.
Evaluation of Energy Efficiency Performance of Heated Windows
NASA Astrophysics Data System (ADS)
Jammulamadaka, Hari Swarup
The study about the evaluation of the performance of the heated windows was funded by the WVU Research Office as a technical assistance award at the 2014 TransTech Energy Business Development Conference to the Green Heated Glass company/project owned by Frank Dlubak. The award supports a WVU researcher to conduct a project important for commercialization. This project was awarded to the WVU Industrial Assessment Center in 2015. The current study attempted to evaluate the performance of the heated windows by developing an experimental setup to test the window at various temperatures by varying the current input to the window. The heated double pane window was installed in an insulated box. A temperature gradient was developed across the window by cooling one side of the window using gel based ice packs. The other face of the window was heated by passing current at different wattages through the window. The temperature of the inside and outside panes, current and voltage input, room and box temperature were recorded, and used to calculate the apparent R-value of the window when not being heated vs when being heated. It has been concluded from the study that the heated double pane window is more effective in reducing heat losses by as much as 50% than a non-heated double pane window, if the window temperature is maintained close to the room temperature. If the temperature of the window is much higher than the room temperature, the losses through the window appear to increase beyond that of a non-heated counterpart. The issues encountered during the current round of experiments are noted, and recommendations provided for future studies.
DTK C/Fortran Interface Development for NEAMS FSI Simulations
DOE Office of Scientific and Technical Information (OSTI.GOV)
Slattery, Stuart R.; Lebrun-Grandie, Damien T.
This report documents the development of DataTransferKit (DTK) C and Fortran interfaces for fluid-structure-interaction (FSI) simulations in NEAMS. In these simulations, the codes Nek5000 and Diablo are being coupled within the SHARP framework to study flow-induced vibration (FIV) in reactor steam generators. We will review the current Nek5000/Diablo coupling algorithm in SHARP and the current state of the solution transfer scheme used in this implementation. We will then present existing DTK algorithms which may be used instead to provide an improvement in both flexibility and scalability of the current SHARP implementation. We will show how these can be used withinmore » the current FSI scheme using a new set of interfaces to the algorithms developed by this work. These new interfaces currently expose the mesh-free solution transfer algorithms in DTK, a C++ library, and are written in C and Fortran to enable coupling of both Nek5000 and Diablo in their native Fortran language. They have been compiled and tested on Cooley, the test-bed machine for Mira at ALCF.« less
ERIC Educational Resources Information Center
Regan, Tiffany Arnett
2017-01-01
The purpose of this descriptive case study was to identify teacher strengths and needs to create a site-specific professional development program for literacy. I was interested in studying how to identify teacher needs and strengths and explore the compatibility between teacher beliefs, current practice, and best practices in literacy. This study…
ERIC Educational Resources Information Center
George, Carole A.
This document describes a study that designed, developed, and evaluated the Pennsylvania school-district database program for use by educational decision makers. The database contains current information developed from data provided by the Pennsylvania Department of Education and describes each of the 500 active school districts in the state. PEP…
Motor Development in Children at Risk of Autism: A Follow-Up Study of Infant Siblings
ERIC Educational Resources Information Center
Leonard, Hayley C.; Bedford, Rachael; Charman, Tony; Elsabbagh, Mayada; Johnson, Mark H.; Hill, Elisabeth L.
2014-01-01
Recently, evidence of poor or atypical motor skills in autism spectrum disorder has led some to argue that motor impairment is a core feature of the condition. The current study uses a longitudinal prospective design to assess the development of motor skills of 20 children at increased risk of developing autism spectrum disorder, who were…
NASA's current activities in free space optical communications
NASA Astrophysics Data System (ADS)
Edwards, Bernard L.
2017-11-01
NASA and other space agencies around the world are currently developing free space optical communication systems for both space-to-ground links and space-to-space links. This paper provides an overview of NASA's current activities in free space optical communications with a focus on Near Earth applications. Activities to be discussed include the Lunar Laser Communication Demonstration, the Laser Communications Relay Demonstration, and the commercialization of the underlying technology. The paper will also briefly discuss ongoing efforts and studies for Deep Space optical communications. Finally the paper will discuss the development of international optical communication standards within the Consultative Committee for Space Data Systems.
High-Resolution Methods for Diagnosing Cartilage Damage In Vivo
Novakofski, Kira D.; Pownder, Sarah L.; Koff, Matthew F.; Williams, Rebecca M.; Potter, Hollis G.; Fortier, Lisa A.
2016-01-01
Advances in current clinical modalities, including magnetic resonance imaging and computed tomography, allow for earlier diagnoses of cartilage damage that could mitigate progression to osteoarthritis. However, current imaging modalities do not detect submicrometer damage. Developments in in vivo or arthroscopic techniques, including optical coherence tomography, ultrasonography, bioelectricity including streaming potential measurement, noninvasive electroarthrography, and multiphoton microscopy can detect damage at an earlier time point, but they are limited by a lack of penetration and the ability to assess an entire joint. This article reviews current advancements in clinical and developing modalities that can aid in the early diagnosis of cartilage injury and facilitate studies of interventional therapeutics. PMID:26958316
The importance of the past in public health
Scally, G.; Womack, J.
2004-01-01
Study objective: To explore the role of history in public health and its relevance to current practice and professional development. Design: An analysis of the issues surrounding the poor attention paid to the history of public health by its current practitioners. Setting: The paper is written from the perspective of practitioners in the UK but has wide applicability. Main results: The paper makes the case that the current neglect of public health history is to the detriment of public health practice. Conclusions: There is a strong case for more attention to be paid to public health history in professional formation, development, and communication. PMID:15310800
Integrated Strike Avionics Study. Volume 1
1980-10-01
MMW Systems Targeting Studies Perf. Meas. o C02 Laser Radar Ses. St. Army Obstacle Detect Prog. Concept Demo Mobile System 20 ’ - I...Fabrication and Test o FLIR Field of View & Classification Study (FLIR FACS) Definition m Development & Test 4. Aplicability of Current Programs to...FY80 81 8283 84 85 o LANTIRN 1 n Imaoinn Sensor Autoprocessor • o Forward Looking Active Class a 4. Aplicability of Current Program Required The need
Biomarkers for Cystic Fibrosis Drug Development
Muhlebach, Marianne S.; Clancy, JP; Heltshe, Sonya L.; Ziady, Assem; Kelley, Tom; Accurso, Frank; Pilewski, Joseph; Mayer-Hamblett, Nicole; Joseloff, Elizabeth; Sagel, Scott D.
2016-01-01
Purpose To provide a review of the status of biomarkers in cystic fibrosis drug development, including regulatory definitions and considerations, a summary of biomarkers in current use with supportive data, current gaps, and future needs. Methods Biomarkers are considered across several areas of CF drug development, including cystic fibrosis transmembrane conductance regulator modulation, infection, and inflammation. Results Sweat chloride, nasal potential difference, and intestinal current measurements have been standardized and examined in the context of multicenter trials to quantify CFTR function. Detection and quantification of pathogenic bacteria in CF respiratory cultures (e.g.: Pseudomonas aeruginosa) is commonly used in early phase antimicrobial clinical trials, and to monitor safety of therapeutic interventions. Sputum (e.g.: neutrophil elastase, myeloperoxidase, calprotectin) and blood biomarkers (e.g.: C reactive protein, calprotectin, serum amyloid A) have had variable success in detecting response to inflammatory treatments. Conclusions Biomarkers are used throughout the drug development process in CF, and many have been used in early phase clinical trials to provide proof of concept, detect drug bioactivity, and inform dosing for later-phase studies. Advances in the precision of current biomarkers, and the identification of new biomarkers with ‘omics-based technologies, are needed to accelerate CF drug development. PMID:28215711
NASA Astrophysics Data System (ADS)
Lay, W.-S.; Raman, R.; Jarboe, T. R.; Nelson, B. A.; Mueller, D.; Ebrahimi, F.; Ono, M.; Jardin, S. C.; Taylor, G.
2017-10-01
At present about 20% of the total plasma current required for sustained operation has been generated by transient CHI. The present understanding suggests that it may be possible to generate all of the needed current in a ST / tokamak using transient CHI. In such a scenario, one could transition directly from a CHI produced plasma to a non-inductively sustained plasma, without the difficult intermediate step that involves non-inductive current ramp-up. STs based on this new configuration would take advantage of evolving developments in high-temperature superconductor technology to develop a simpler design ST that relies primarily on CHI for plasma current generation. Motivated by the very good results from NSTX and HIT-II, we are examining the potential application of transient CHI for reactor configurations through these studies. (1) Study of the maximum levels of start-up currents that could be generated on NSTX-U, (2) application of a single biased electrode configuration on QUEST to protect the insulator from neutron damage in a CHI reactor installation, and (3) QUEST-like, but a double biased electrode configuration for PEGASUS and NSTX-U. Results from these on-going studies will be described. This work is supported by U.S. DOE Contracts: DE-AC02-09CH11466, DE-FG02-99ER54519 AM08, and DE-SC0006757.
The National Children's Study (NCS) is a federally-sponsored, longitudinal study of environmental influences on the health and development of children across the United States (www.nationalchildrensstudy.gov). Current plans are to study approximately 100,000 children and their f...
ERIC Educational Resources Information Center
Panichpongsapak, Ratthasart; Tesaputa, Kowat; Sri-ampai, Anan
2016-01-01
The aims of this research were: (1) to study the factors and indicators to enhance curriculum and learning management competency of private primary school teachers; (2) to study current situations and desirable situations and techniques; (3) to develop a program; and (4) to study the effects of a program. The study comprised 4 phases: Phase…
Current Fluctuations in Stochastic Lattice Gases
NASA Astrophysics Data System (ADS)
Bertini, L.; de Sole, A.; Gabrielli, D.; Jona-Lasinio, G.; Landim, C.
2005-01-01
We study current fluctuations in lattice gases in the macroscopic limit extending the dynamic approach for density fluctuations developed in previous articles. More precisely, we establish a large deviation theory for the space-time fluctuations of the empirical current which include the previous results. We then estimate the probability of a fluctuation of the average current over a large time interval. It turns out that recent results by Bodineau and Derrida [Phys. Rev. Lett.922004180601] in certain cases underestimate this probability due to the occurrence of dynamical phase transitions.
Electric breakdown during the pulsed current spreading in the sand
DOE Office of Scientific and Technical Information (OSTI.GOV)
Vasilyak, L. M., E-mail: vasilyak@ihed.ras.ru; Vetchinin, S. P.; Panov, V. A.
2016-03-15
Processes of spreading of the pulsed current from spherical electrodes and an electric breakdown in the quartz sand are studied experimentally. When the current density on the electrode exceeds the critical value, a nonlinear reduction occurs in the grounding resistance as a result of sparking in the soil. The critical electric field strengths for ionization and breakdown are determined. The ionization-overheating instability is shown to develop on the electrode, which leads to the current contraction and formation of plasma channels.
Cross-situational statistical word learning in young children.
Suanda, Sumarga H; Mugwanya, Nassali; Namy, Laura L
2014-10-01
Recent empirical work has highlighted the potential role of cross-situational statistical word learning in children's early vocabulary development. In the current study, we tested 5- to 7-year-old children's cross-situational learning by presenting children with a series of ambiguous naming events containing multiple words and multiple referents. Children rapidly learned word-to-object mappings by attending to the co-occurrence regularities across these ambiguous naming events. The current study begins to address the mechanisms underlying children's learning by demonstrating that the diversity of learning contexts affects performance. The implications of the current findings for the role of cross-situational word learning at different points in development are discussed along with the methodological implications of employing school-aged children to test hypotheses regarding the mechanisms supporting early word learning. Copyright © 2014 Elsevier Inc. All rights reserved.
Morelen, Diana; Thomassin, Kristel
2013-01-01
The current review paper summarizes the literature on parental emotion socialization in ethnically diverse families in the United States. Models of emotion socialization have been primarily developed using samples of European American parents and children. As such, current categorizations of “adaptive” and “maladaptive” emotion socialization practices may not be applicable to individuals from different ethnic backgrounds. The review examines current models of emotion socialization, with particular attention paid to the demographic breakdown of the studies used to develop these models. Additionally, the review highlights studies examining emotion socialization practices in African American, Asian American, and Latin American families. The review is synthesized with summarizing themes of similarities and differences across ethnic groups, and implications for culturally sensitive research and practice are discussed. PMID:23766738
Mercury Content of Sediments in East Fork Poplar Creek: Current Assessment and Past Trends
DOE Office of Scientific and Technical Information (OSTI.GOV)
Brooks, Scott C.; Eller, Virginia A.; Dickson, Johnbull O.
2017-01-01
This study provided new information on sediment mercury (Hg) and monomethylmercury (MMHg) content and chemistry. The current inventory of Hg in East Fork Poplar Creek (EFPC) bed sediments was estimated to be 334 kg, which represents a ~67% decrease relative to the initial investigations in 1984. MMHg sediment inventory was estimated to be 44.1 g, lower but roughly similar to past estimates. The results support the relevance and potential impacts of other active and planned investigations within the Mercury Remediation Technology Development for Lower East Fork Poplar Creek project (e.g., assessment and control of bank soil inputs, sorbents for Hgmore » and MMHg removal, re-introduction of freshwater clams to EFPC), and identify gaps in current understanding that represent opportunities to understand controlling variables that may inform future technology development studies.« less
Exploring Preschool Teachers' Technological Pedagogical Content Knowledge of Educational Games
ERIC Educational Resources Information Center
Hsu, Chung-Yuan; Liang, Jyh-Chong; Chai, Ching-Sing; Tsai, Chin-Chung
2013-01-01
Current technological pedagogical content knowledge (TPACK) studies are inclined to treat technology in a general manner, an approach which may not be able to provide adequate guidelines to improve teacher preparation and professional development when teaching with games. This study developed two new questionnaires, namely the Technological…
Study of Problems of Individual's Social Education
ERIC Educational Resources Information Center
Duisenbayev, Abay K.; Baltymova, Mira R.; Akzholova, Aktoty T.; Bazargaliyev, Gabit B.; Zhumagaziyev, Arman Zh.
2016-01-01
The importance of the study of social education of the individual as an integral process covering all stages of human development, supported by factors of modern development of children, adolescents, youth in the conditions of reforming education. Currently, the scientific literature has accumulated a sufficient fund of theoretical knowledge,…
ERIC Educational Resources Information Center
Li, Shuang; Zizzi, Sam
2018-01-01
Previous literature has focused on international student's social transition and monocultural and bicultural ties. Little research has explored international students' multicultural friendship development and the role that physical activity plays in their social interaction. The current case study explored a group of international students'…
DOE Office of Scientific and Technical Information (OSTI.GOV)
Matwiyoff, N.A.
1976-01-01
The prospects for the broad scale development of the utility of stable isotopes in science, medicine, agriculture, and environmental studies are considered with emphasis on the current status of isotope production, synthesis of isotopically labelled compounds, and analytical techniques.
Resourcing the Training and Development Function. IES Report.
ERIC Educational Resources Information Center
Carter, A.; Hirsh, W.; Aston, J.
A study explored current practice in organizing and resourcing training and development (T&D) using survey responses from over 100 major private and public sector employers and case studies of T&D functions in 6 organizations. Business drivers for T&D were senior management as customers; diagnosis of training as "the…
The Development Effectiveness Management Model for Sub-District Secondary School
ERIC Educational Resources Information Center
Butsankom, Akachai; Sirishuthi, Chaiyuth; Lammana, Preeda
2016-01-01
The purposes of this research were to study the factors of effectiveness management model for subdistrict secondary school, to investigate current situations and desirable situations of effectiveness management model for sub-district secondary school, to develop the effectiveness management model for sub-district secondary school and to study the…
PEM Electrolysis H2A Production Case Study Documentation
DOE Office of Scientific and Technical Information (OSTI.GOV)
James, Brian; Colella, Whitney; Moton, Jennie
2013-12-31
This report documents the development of four DOE Hydrogen Analysis (H2A) case studies for polymer electrolyte membrane (PEM) electrolysis. The four cases characterize PEM electrolyzer technology for two hydrogen production plant sizes (Forecourt and Central) and for two technology development time horizons (Current and Future).
1978 Decision-Making Casebook for Business and Economics.
ERIC Educational Resources Information Center
Tedesco, Paul H., Ed.; And Others
These teacher developed case studies taken from the business world are presented to help secondary students develop an understanding of economics and of the decision-making process. The studies describe real business situations. All historical and current facts are provided, and students must analyze the data and make business decisions. Teacher…
ERIC Educational Resources Information Center
Graziano, Paulo A.; Calkins, Susan D.; Keane, Susan P.
2011-01-01
The current study examined the role of maternal behaviour and toddlers' emotion regulation strategies in the development of children's sustained attention abilities. Participants for this study included 447 children (232 girls) obtained from three different cohorts participating in a larger ongoing longitudinal study. When the children were 2…
Development of System Thinking Skills in the Context of Earth System Education
ERIC Educational Resources Information Center
Assaraf, Orit Ben-Zvi; Orion, Nir
2005-01-01
The current study deals with the development of system thinking skills at the junior high school level. The sample population included about 50 eighth-grade students from two different classes of an urban Israeli junior high school who studied an earth systems-based curriculum that focused on the hydro cycle. The study addressed the following…
A Multiple Case Study of Verbal Short-Term Memory in Velo-Cardio-Facial Syndrome
ERIC Educational Resources Information Center
Majerus, S.; Glaser, B.; Van der Linden, M.; Eliez, S.
2006-01-01
Background: Velo-cardio-facial syndrome (VCFS, 22q 11.2 deletion) is characterized by severely delayed language development. The current study explored the integrity of verbal short-term memory (STM), a cognitive function critically involved in language development, in eight children with VCFS. Methods: Using a multiple case study design, we…
Current and anticipated uses of the CATHARE code at EDF and FRAMATOME
DOE Office of Scientific and Technical Information (OSTI.GOV)
Gandrille, J.L.; Vacher, J.L.; Poizat, F.
1997-07-01
This paper presents current industrial applications of the CATHARE code in the fields of Safety Studies and Simulators where the code is intensively used by FRAMATOME, EDF and CEA, the development partners of CATHARE. Future needs in these fields are also recapitulated.
FINANCIAL ANALYSIS OF CURRENT OPERATIONS OF COLLEGES AND UNIVERSITIES.
ERIC Educational Resources Information Center
SWANSON, JOHN E.; AND OTHERS
TECHNIQUES FOR DEVELOPING FINANCIAL AND RELATED COST-EFFECTIVENESS DATA FOR PUBLIC AND PRIVATELY SUPPORTED AMERICAN COLLEGES AND UNIVERSITIES WERE STUDIED TO FORMULATE PRINCIPLES, PROCEDURES, AND STANDARDS FOR THE ACCUMULATION AND ANALYSES OF CURRENT OPERATING COSTS. AFTER SEPARATE ANALYSES OF INSTITUTIONAL PROCEDURES AND REPORTS, ANALYTIC UNITS…
Teaching Math Online: Current Practices in Turkey
ERIC Educational Resources Information Center
Akdemir, Omur
2011-01-01
Changing nature of student population, developments in technology, and insufficient number of traditional universities have made online courses popular around the globe. This study was designed to investigate the current practices of teaching mathematics online in Turkish Universities through a qualitative inquiry. The snowball sampling method was…
DOE Office of Scientific and Technical Information (OSTI.GOV)
Lowry, Thomas Stephen; Finger, John T.; Carrigan, Charles R.
This report documents the key findings from the Reservoir Maintenance and Development (RM&D) Task of the U.S. Department of Energy's (DOE), Geothermal Technologies Office (GTO) Geothermal Vision Study (GeoVision Study). The GeoVision Study had the objective of conducting analyses of future geothermal growth based on sets of current and future geothermal technology developments. The RM&D Task is one of seven tasks within the GeoVision Study with the others being, Exploration and Confirmation, Potential to Penetration, Institutional Market Barriers, Environmental and Social Impacts, Thermal Applications, and Hybrid Systems. The full set of findings and the details of the GeoVision Study canmore » be found in the final GeoVision Study report on the DOE-GTO website. As applied here, RM&D refers to the activities associated with developing, exploiting, and maintaining a known geothermal resource. It assumes that the site has already been vetted and that the resource has been evaluated to be of sufficient quality to move towards full-scale development. It also assumes that the resource is to be developed for power generation, as opposed to low-temperature or direct use applications. This document presents the key factors influencing RM&D from both a technological and operational standpoint and provides a baseline of its current state. It also looks forward to describe areas of research and development that must be pursued if the development geothermal energy is to reach its full potential.« less
Exploring the Role of Usability in the Software Process: A Study of Irish Software SMEs
NASA Astrophysics Data System (ADS)
O'Connor, Rory V.
This paper explores the software processes and usability techniques used by Small and Medium Enterprises (SMEs) that develop web applications. The significance of this research is that it looks at development processes used by SMEs in order to assess to what degree usability is integrated into the process. This study seeks to gain an understanding into the level of awareness of usability within SMEs today and their commitment to usability in practice. The motivation for this research is to explore the current development processes used by SMEs in developing web applications and to understand how usability is represented in those processes. The background for this research is provided by the growth of the web application industry beyond informational web sites to more sophisticated applications delivering a broad range of functionality. This paper presents an analysis of the practices of several Irish SMEs that develop web applications through a series of case studies. With the focus on SMEs that develop web applications as Management Information Systems and not E-Commerce sites, informational sites, online communities or web portals. This study gathered data about the usability techniques practiced by these companies and their awareness of usability in the context of the software process in those SMEs. The contribution of this study is to further the understanding of the current role of usability within the software development processes of SMEs that develop web applications.
NASA Astrophysics Data System (ADS)
Shi, Wei; Hu, Xiaosong; Jin, Chao; Jiang, Jiuchun; Zhang, Yanru; Yip, Tony
2016-05-01
With the development and popularization of electric vehicles, it is urgent and necessary to develop effective management and diagnosis technology for battery systems. In this work, we design a parallel battery model, according to equivalent circuits of parallel voltage and branch current, to study effects of imbalanced currents on parallel large-format LiFePO4/graphite battery systems. Taking a 60 Ah LiFePO4/graphite battery system manufactured by ATL (Amperex Technology Limited, China) as an example, causes of imbalanced currents in the parallel connection are analyzed using our model, and the associated effect mechanisms on long-term stability of each single battery are examined. Theoretical and experimental results show that continuously increasing imbalanced currents during cycling are mainly responsible for the capacity fade of LiFePO4/graphite parallel batteries. It is thus a good way to avoid fast performance fade of parallel battery systems by suppressing variations of branch currents.
Dimensions of service quality in healthcare: a systematic review of literature.
Fatima, Iram; Humayun, Ayesha; Iqbal, Usman; Shafiq, Muhammad
2018-06-13
Various dimensions of healthcare service quality were used and discussed in literature across the globe. This study presents an updated meaningful review of the extensive research that has been conducted on measuring dimensions of healthcare service quality. Systematic review method in current study is based on PRISMA guidelines. We searched for literature using databases such as Google, Google Scholar, PubMed and Social Science, Citation Index. In this study, we screened 1921 identified papers using search terms/phrases. Snowball strategies were adopted to extract published articles from January 1997 till December 2016. Two-hundred and fourteen papers were identified as relevant for data extraction; completed by two researchers, double checked by the other two to develop agreement in discrepancies. In total, 74 studies fulfilled our pre-defined inclusion and exclusion criteria for data analysis. Service quality is mainly measured as technical and functional, incorporating many sub-dimensions. We synthesized the information about dimensions of healthcare service quality with reference to developed and developing countries. 'Tangibility' is found to be the most common contributing factor whereas 'SERVQUAL' as the most commonly used model to measure healthcare service quality. There are core dimensions of healthcare service quality that are commonly found in all models used in current reviewed studies. We found a little difference in these core dimensions while focusing dimensions in both developed and developing countries, as mostly SERVQUAL is being used as the basic model to either generate a new one or to add further contextual dimensions. The current study ranked the contributing factors based on their frequency in literature. Based on these priorities, if factors are addressed irrespective of any context, may lead to contribute to improve healthcare quality and may provide an important information for evidence-informed decision-making.
Interactive Relationships with Computers in Teaching Reading.
ERIC Educational Resources Information Center
Doublier, Rene M.
This study summarizes recent achievements in the expanding development of man/machine communications and reviews current technological hurdles associated with the development of artificial intelligence systems which can generate and recognize human speech patterns. With the development of such systems, one potential application would be the…
Exploring the Relevant Antecedents of Superintendent Leadership Skills
ERIC Educational Resources Information Center
Hartley, Lloyd
2012-01-01
Understanding antecedents to superintendent leadership development is crucial for the continued improvement of schools. This qualitative study seeks to identify skills superintendents consider critical to their position, antecedents that developed those skills, and provide an increased understanding of the methods needed for developing current and…
Studies of the Codeposition of Cobalt Hydroxide and Nickel Hydroxide
NASA Technical Reports Server (NTRS)
Ho, C. H.; Murthy, M.; VanZee, J. W.
1997-01-01
Topics considered include: chemistry, experimental measurements, planar film model development, impregnation model development, results and conclusion. Also included: effect of cobalt concentration on deposition/loading; effect of current density on loading distribution.
ERIC Educational Resources Information Center
Tones, Megan; Pillay, Hitendra; Kelly, Kathy
2011-01-01
More recently, lifespan development psychology models of adaptive development have been applied to the workforce to investigate ageing worker and lifespan issues. The current study uses the Learning and Development Survey (LDS) to investigate employee selection and engagement of learning and development goals and opportunities and constraints for…
Current State and Future Prospects of Education for Sustainable Development (ESD) in Japan
ERIC Educational Resources Information Center
Tanaka, Haruhiko
2017-01-01
The UN Decade of Education for Sustainable Development (ESD) ran from 2005 to 2014. This study concerns the concepts of Sustainable Development (SD) and ESD. The term "sustainable development" was coined by the Brundtland Commission in 1987 as the key word in integrating environment and development. SD achieved international consensus at…
Army Aviation Maintenance Career Management Field 67 Study
1980-10-08
Occupational Specialties (MOS) Specifications 121 Current Inventory Impacts 121 MOS Substitutability 122 Elimination of MOS 67W 123 *ilization of Females in CMF...Operating Strength 67 3-6 Impact of New MACRIT on TOE 78 3-7 67 Series Authorizations Without Technical Supervision 81 3-8 68 Series Authorizations...restructuring and duty realignment necessitated the development of new MOS duty descriptions. (6) CURRENT INVENTORY IMPACT . A comparison of current and
Development and planning and design of equipment pumping generator of semiconductor lasers
NASA Technical Reports Server (NTRS)
Popkov, A. V.
1974-01-01
The schematic of a multidimensional current pulse generator is studied. A MTKh-90 cold cathode thyratron is used as the current commutator. In the autooscillation mode on a frequency of 380 hertz the generator creates a current to 100 amps per pulse in a control resistance of 1 ohm. The pulse duration is regulated within the limits from 0.1 to 3.0 microseconds.
Suba, Dávid; Urbányi, Zoltán; Salgó, András
2016-10-01
Capillary electrophoresis techniques are widely used in the analytical biotechnology. Different electrophoretic techniques are very adequate tools to monitor size-and charge heterogenities of protein drugs. Method descriptions and development studies of capillary zone electrophoresis (CZE) have been described in literature. Most of them are performed based on the classical one-factor-at-time (OFAT) approach. In this study a very simple method development approach is described for capillary zone electrophoresis: a "two-phase-four-step" approach is introduced which allows a rapid, iterative method development process and can be a good platform for CZE method. In every step the current analytical target profile and an appropriate control strategy were established to monitor the current stage of development. A very good platform was established to investigate intact and digested protein samples. Commercially available monoclonal antibody was chosen as model protein for the method development study. The CZE method was qualificated after the development process and the results were presented. The analytical system stability was represented by the calculated RSD% value of area percentage and migration time of the selected peaks (<0.8% and <5%) during the intermediate precision investigation. Copyright © 2016 Elsevier B.V. All rights reserved.
Jahromi, Hamed Dehdashti; Mahmoodi, Ali; Sheikhi, Mohammad Hossein; Zarifkar, Abbas
2016-10-20
Reduction of dark current at high-temperature operation is a great challenge in conventional quantum dot infrared photodetectors, as the rate of thermal excitations resulting in the dark current increases exponentially with temperature. A resonant tunneling barrier is the best candidate for suppression of dark current, enhancement in signal-to-noise ratio, and selective extraction of different wavelength response. In this paper, we use a physical model developed by the authors recently to design a proper resonant tunneling barrier for quantum infrared photodetectors and to study and analyze the spectral response of these devices. The calculated transmission coefficient of electrons by this model and its dependency on bias voltage are in agreement with experimental results. Furthermore, based on the calculated transmission coefficient, the dark current of a quantum dot infrared photodetector with a resonant tunneling barrier is calculated and compared with the experimental data. The validity of our model is proven through this comparison. Theoretical dark current by our model shows better agreement with the experimental data and is more accurate than the previously developed model. Moreover, noise in the device is calculated. Finally, the effect of different parameters, such as temperature, size of quantum dots, and bias voltage, on the performance of the device is simulated and studied.
NASA Astrophysics Data System (ADS)
Hirata, H.; Kawamura, R.; Kato, M.; Shinoda, T.
2014-12-01
We investigated how the moisture supply from the Kuroshio Current/Kuroshio Extension affects the rapid intensification of an explosive cyclone using a couple atmosphere-ocean non-hydrostatic model, CReSS-NHOES. The Cloud-Resolving Storm Simulator (CReSS) and the Non-Hydrostatic Ocean model for the Earth Simulator (NHOES) have been developed by the Hydrospheric Atmospheric Research Center of Nagoya University and the Japan Agency for Marine-Earth Science and Technology, respectively. We performed a numerical simulation of an extratropical cyclone migrating along the southern periphery of the Kuroshio Current on January 14, 2013, that developed most rapidly in recent years in the vicinity of Japan. The evolutions of surface fronts related to the cyclone simulated by the CReSS-NHOES closely resemble Shapiro-Keyser model. In the lower troposphere, the cyclone's bent-back front and the associated frontal T-bone structure become evident with the cyclone development. Cold Conveyor Belt (CCB) is also well organized over the northern part of the cyclone. During its developing stage, since the CCB dominates just over the Kuroshio Current/Kuroshio Extension, a large amount of moisture is efficiently supplied from the warm current into the CCB. The vapor evaporated from the underlying warm current is transported into the bent-back front by the CCB and converges horizontally in the vicinity of the front. As a result, strong diabatic heating arises over the corresponding moisture convergence area in that vicinity, indicating that the abundant moisture due to the warm current plays a vital role in rapid development of the cyclone through latent heat release processes. Both processes of the moisture transport from the warm current into the cyclone system via the CCB and of the latent heat release around the bent-back front are also confirmed by trajectory analyses. The rapid SLP decrease of the cyclone center can in turn increase the moisture supply from the warm current through enhancement of the CCB. We anticipate that such a feedback process plays a key role in the rapid intensification of the cyclone highlighted in this study.
Development of Effective Academic Affairs Administration System in Thai Primary Schools
ERIC Educational Resources Information Center
Thongnoi, Niratchakorn; Srisa-ard, Boonchom; Sri-ampai, Anan
2013-01-01
This research aimed to: 1) study current situations and problems of academic affairs administration system in Primary Schools. 2) develop an effective academic affairs administration system, and 3) evaluate the implementation of the developed system in the primary school, Thailand. Research and Development (R&D) was employed which consisted of…
ERIC Educational Resources Information Center
Chowdhary, Bhawna; Liu, Xiufeng; Yerrick, Randy; Smith, Erica; Grant, Brooke
2014-01-01
The current literature relates to how teachers develop knowledge and practice of science inquiry, but little has been reported on how teachers develop interdisciplinary science inquiry (ISI) knowledge and practice. This study examines the effect of university research experiences, ongoing professional development, and in-school support on…
Learning about Whole-Class Scaffolding from a Teacher Professional Development Study
ERIC Educational Resources Information Center
Visnovska, Jana; Cobb, Paul
2015-01-01
The importance of teachers developing adaptive instructional practices consistent with metaphor of whole-class scaffolding has been well documented. However, teachers' development of such practices is currently not well understood. We draw on a 5-year professional development (PD) design experiment in which a group of middle school mathematics…
NASA communications technology research and development
NASA Technical Reports Server (NTRS)
Durham, A. F.; Stankiewicz, N.
1979-01-01
The development of a 1978 NASA study to identify technology requirements is surveyed, and its principal conclusions, recommendations, and priorities are summarized. In addition, antenna, traveling wave tube, and solid state amplifier developments representing selected items from the current communications technology development programs at the NASA Lewis Research and Goddard Space Flight Centers are described.
Current Practices in Resident Assistant Training
ERIC Educational Resources Information Center
Koch, Virginia Albaneso
2016-01-01
Developing resident assistant (RA) training is a challenge for most housing and residence life staff. Grounded in the author's doctoral research on the curricular design of RA training programs, this study summarizes current practices in three types of RA training programs--preservice training, in-service training, and academic courses--and…
Distance Education Programs in Social Work: Current and Emerging Trends
ERIC Educational Resources Information Center
Vernon, Robert; Vakalahi, Halaevalu; Pierce, Dean; Pittman-Munke, Peggy; Adkins, Lynn Frantz
2009-01-01
This article reports on current and emerging trends in the use of distance education technologies in social work education. Areas studied include the extent of distance education programs, curricular areas covered, technologies used, pedagogical approaches, intentions for degree-program development, sources of pressure to adopt distance education…
Feedback: Implications for Further Research and Study.
ERIC Educational Resources Information Center
Nishikawa, Sue S.
This report reviews current literature on feedback and suggests practical implications of feedback research for educators. A definition of feedback is offered, and past definitions in prior research are noted. An analysis of the current state of knowledge of feedback discusses the historical development of feedback theory and suggests that…
Current Trends in Distance Education: An Administrative Model
ERIC Educational Resources Information Center
Compora, Daniel P.
2003-01-01
Current practices and procedures of distance education programs at selected institutions in higher education in Ohio were studied. Relevant data was found in the areas of: (1) content of the distance education program's mission statement; (2) needs assessment procedures; (3) student demographics; (4) course acquisition, development, and evaluation…
Potential Vaccines and Post-Exposure Treatments for Filovirus Infections
Friedrich, Brian M.; Trefry, John C.; Biggins, Julia E.; Hensley, Lisa E.; Honko, Anna N.; Smith, Darci R.; Olinger, Gene G.
2012-01-01
Viruses of the family Filoviridae represent significant health risks as emerging infectious diseases as well as potentially engineered biothreats. While many research efforts have been published offering possibilities toward the mitigation of filoviral infection, there remain no sanctioned therapeutic or vaccine strategies. Current progress in the development of filovirus therapeutics and vaccines is outlined herein with respect to their current level of testing, evaluation, and proximity toward human implementation, specifically with regard to human clinical trials, nonhuman primate studies, small animal studies, and in vitro development. Contemporary methods of supportive care and previous treatment approaches for human patients are also discussed. PMID:23170176
NASA Astrophysics Data System (ADS)
Morales, A. C.; Paez, D.; Arango, C.
2015-08-01
To analyze the current situation of Colombian regulation, it is necessary to compare some specific aspects with the legislation used in other countries where the UAVs topic dates to many years ago. This study is focused on evaluating all the possibilities to make the Colombian regulation effective without closing opportunities of research and development growth, but still guarantee the privacy and intimacy rights of the population. Results from our study are currently being used in the development of the Colombian regulation and they are proven useful to instigate informative debates and identify areas where specific needs are to be address in Colombia.
Causes of Death Among 379 Patients With Hemophilia: A Developing Country's Report.
Mansouritorghabeh, Hassan; Rahimi, Hossein; Mohades, Seyed Tahereh; Behboudi, Maryam
2018-05-01
There are steps to achieve an optimum life for patients with hemophilia in developing countries, and awareness of the pattern of death in patients with hemophilia is a prerequisite for any health-care program. Owing to the lack of any data on the pattern of death in patients with hemophilia from developing countries, the current study was done to address common causes of death, and the spectrum of causes of death among individuals with hemophilia A and B. To address the pattern of death in northeast of Iran, we retrospectively collected demographic data regarding deceased patients with hemophilia A and B. Overall, among 379 people with hemophilia A and B, there were 46 deaths. Thirty-two deaths happened in the severe forms of the diseases. The obtained results show the patterns of death in the patients studied are not as parallel as some reports from the developed countries. Traumatic and spontaneous bleeding events were the main causes of death. The trend of death shows a decrease in the current decade post better therapeutic facilities. Evaluation of causes of death in hemophilia can be a useful indicator for managing the efficacy of health care in the current patients.
The Development of Individuation in Autism
ERIC Educational Resources Information Center
O'Hearn, Kirsten; Franconeri, Steven; Wright, Catherine; Minshew, Nancy; Luna, Beatriz
2013-01-01
Evidence suggests that people with autism rely less on holistic visual information than typical adults. The current studies examine this by investigating core visual processes that contribute to holistic processing--namely, individuation and element grouping--and how they develop in participants with autism and typically developing (TD)…
Development of a School Leadership Evaluation System
ERIC Educational Resources Information Center
Orlando, Nik
2014-01-01
This action research study examined the effectiveness of the process implemented by Partnerships to Uplift Communities (PUC) Schools Charter Management Organization to develop their school leader evaluation system in collaboration with current PUC school leaders. The development of the leadership evaluation system included the collective voices of…
NASA Astrophysics Data System (ADS)
Arief, I. S.; Suherman, I. H.; Wardani, A. Y.; Baidowi, A.
2017-05-01
Control and monitoring system is a continuous process of securing the asset in the Marine Current Renewable Energy. A control and monitoring system is existed each critical components which is embedded in Failure Mode Effect Analysis (FMEA) method. As the result, the process in this paper developed through a matrix sensor. The matrix correlated to critical components and monitoring system which supported by sensors to conduct decision-making.
NASA Astrophysics Data System (ADS)
Jarboe, Thomas; Marklin, George; Nelson, Brian; Sutherland, Derek; HIT Team Team
2013-10-01
A proof of principle experiment to study closed-flux energy confinement of a spheromak sustained by imposed dynamo current drive is described. A two-fluid validated NIMROD code has simulated closed-flux sustainment on a stable spheromak using imposed dynamo current drive (IDCD), demonstrating that dynamo current drive is compatible with closed flux. (submitted for publication and see adjacent poster.(spsap)) HIT-SI, a = 0.25 m, has achieved 90 kA of toroidal current, current gains of nearly 4, and operation from 5.5 kHz to 68 kHz, demonstrating the robustness of the method.(spsap) Finally, a reactor design study using fusion technology developed for ITER and modern nuclear technology shows a design that is economically superior to coal.(spsap) The spheromak reactor and development path are about a factor of 10 less expensive than that of the tokamak/stellarator. These exciting results justify a proof of principle (PoP) confinement experiment of a spheromak sustained by IDCD. Such an experiment (R = 1.5 m, a = 1 m, Itor = 3 . 2 MA, n = 4e19/m3, T = 3 keV) is described in detail.
Communication for the development of pastoralism.
Seid, M A; Yoseph, L W; Befekadu, U W; Muhammed, A; Fikre, T Z
2016-11-01
Communication is vital for the socio-economic and cultural development of pastoralists. If used constructively, communication can help to create a favourable environment for change and modernisation. This paper tries to uncover trends in communication as part of pastoral development, emphasising both indigenous and current methods of communication and prevailing constraints. This study reveals that pastoral development interventions in the past have often failed to achieve their goals, due to the centralised, 'top-down' approaches adopted and to reliance on external strategies and channels which ignored the indigenous knowledge and communications systems of pastoralists. Pastoralists have their own well-established communications systems for sharing information on climatic conditions and ecology, as well as economic, social and political issues. Modern communication technologies, especially radio and mobile telephones, are increasingly being used by pastoralists to access current regional information. However, pastoral development in the communications area is currently constrained by the failure of various development agencies and stakeholders to use participatory approaches, and by poor infrastructure and weak capacity. The authors therefore call for the adoption of more participatory and integrated approaches towards communication, the expansion of infrastructure and building of capacity.
NASA Technical Reports Server (NTRS)
Flowers, George T.
1994-01-01
Substantial progress has been made toward the goals of this research effort in the past six months. A simplified rotor model with a flexible shaft and backup bearings has been developed. The model is based upon the work of Ishii and Kirk. Parameter studies of the behavior of this model are currently being conducted. A simple rotor model which includes a flexible disk and bearings with clearance has been developed and the dynamics of the model investigated. The study consists of simulation work coupled with experimental verification. The work is documented in the attached paper. A rotor model based upon the T-501 engine has been developed which includes backup bearing effects. The dynamics of this model are currently being studied with the objective of verifying the conclusions obtained from the simpler models. Parallel simulation runs are being conducted using an ANSYS based finite element model of the T-501.
Homma, Kohei; Okamoto, Satoshi; Mandai, Michiko; Gotoh, Norimoto; Rajasimha, Harsha K.; Chang, Yi-Sheng; Chen, Shan; Li, Wei; Cogliati, Tiziana; Swaroop, Anand; Takahashi, Masayo
2013-01-01
Replacement of dysfunctional or dying photoreceptors offers a promising approach for retinal neurodegenerative diseases, including age-related macular degeneration and retinitis pigmentosa. Several studies have demonstrated the integration and differentiation of developing rod photoreceptors when transplanted in wild type or degenerating retina; however, the physiology and function of the donor cells are not adequately defined. Here, we describe the physiological properties of developing rod photoreceptors that are tagged with GFP driven by the promoter of rod differentiation factor, Nrl. GFP-tagged developing rods show Ca2+ responses and rectifier outward currents that are smaller than those observed in fully developed photoreceptors, suggesting their immature developmental state. These immature rods also exhibit hyperpolarization-activated current (Ih) induced by the activation of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels. When transplanted into the subretinal space of wild type or retinal degeneration mice, GFP-tagged developing rods can integrate into the photoreceptor outer nuclear layer in wild-type mouse retina, and exhibit Ca2+ responses and membrane current comparable to native rod photoreceptors. A proportion of grafted rods develop rhodopsin-positive outer segment-like structures within two weeks after transplantation into the retina of Crx-knockout mice, and produce rectifier outward current and Ih upon membrane depolarization and hyperpolarization. GFP-positive rods derived from induced pluripotent stem (iPS) cells also display similar membrane current Ih as native developing rod photoreceptors, express rod-specific phototransduction genes, and HCN-1 channels. We conclude that Nrl-promoter driven GFP-tagged donor photoreceptors exhibit physiological characteristics of rods and that iPS cell-derived rods in vitro may provide a renewable source for cell replacement therapy. PMID:23495178
Aptamers: novel diagnostic and therapeutic tools for diabetes mellitus and metabolic diseases.
Hu, Jingping; Ye, Mao; Zhou, Zhiguang
2017-03-01
Diabetes mellitus is one of the most common chronic diseases that threatens human health in worldwide populations. Despite enormous efforts invested in the study of diabetes mellitus, the development of precise diagnoses and treatments for this disease remains difficult due to the limitations of current techniques. Therefore, new methods are currently being developed. Aptamers are oligonucleotides that bind to specific target molecules and have been widely applied as diagnostic and therapeutic tools. In recent years, aptamers have been utilized in the study of diabetes mellitus and metabolic diseases. In this review, we highlight recent developments and new perspectives on aptamers in the field of diabetes mellitus and other metabolic diseases. Aptamers could potentially provide the means for efficient diagnoses and therapies against diabetes mellitus.
Weaver, Lesley Jo; Hadley, Craig
2009-01-01
Food insecurity is a significant problem in the developing world, and one that is likely to increase given the current global food crisis spurred by rising oil prices, conversion of food to biofuels, and reduced harvests in the wake of natural disasters. The impacts of food insecurity on nutrition status, growth, and development are well substantiated; less is known about the non-nutritional impacts of food insecurity, such as its effects on mental health. This systematic review assesses current findings regarding the impacts of food insecurity on mental health in developing countries. Both qualitative and quantitative studies are considered. The results of the search reveal that little work has examined these issues directly, and serious methodological flaws are present in many of the existing studies. Gaps in the literature, implications, and research priorities are discussed.
Zika Virus: Recent Advances towards the Development of Vaccines and Therapeutics.
McArthur, Monica A
2017-06-13
Zika is a rapidly emerging public health threat. Although clinical infection is frequently mild, significant neurological manifestations have been demonstrated in infants born to Zika virus (ZIKV) infected mothers. Due to the substantial ramifications of intrauterine infection, effective counter-measures are urgently needed. In order to develop effective anti-ZIKV vaccines and therapeutics, improved animal models and a better understanding of immunological correlates of protection against ZIKV are required. This review will summarize what is currently known about ZIKV, the clinical manifestations and epidemiology of Zika as well as, the development of animal models to study ZIKV infection, host immune responses against ZIKV, and the current state of development of vaccines and therapeutics against ZIKV.
Principles of a multistack electrochemical wastewater treatment design
NASA Astrophysics Data System (ADS)
Elsahwi, Essam S.; Dawson, Francis P.; Ruda, Harry E.
2018-02-01
Electrolyzer stacks in a bipolar architecture (cells connected in series) are desirable since power provided to a stack can be transferred at high voltages and low currents and thus the losses in the power bus can be reduced. The anode electrodes (active electrodes) considered as part of this study are single sided but there are manufacturing cost advantages to implementing double side anodes in the future. One of the main concerns with a bipolar stack implementation is the existence of leakage currents (bypass currents). The leakage current is associated with current paths that are not between adjacent anode and cathode pairs. This leads to non uniform current density distributions which compromise the electrochemical conversion efficiency of the stack and can also lead to unwanted side reactions. The objective of this paper is to develop modelling tools for a bipolar architecture consisting of two single sided cells that use single sided anodes. It is assumed that chemical reactions are single electron transfer rate limited and that diffusion and convection effects can be ignored. The design process consists of the flowing two steps: development of a large signal model for the stack, and then the extraction of a small signal model from the large signal model. The small signal model facilitates the design of a controller that satisfies current or voltage regulation requirements. A model has been developed for a single cell and two cells in series but can be generalized to more than two cells in series and to incorporate double sided anode configurations in the future. The developed model is able to determine the leakage current and thus provide a quantitative assessment on the performance of the cell.
ERIC Educational Resources Information Center
Strauss, Gregory P.; Allen, Daniel N.; Jorgensen, Melinda L.; Cramer, Stacey L.
2005-01-01
Previous studies have examined the reliability of scores derived from various Stroop tasks. However, few studies have compared reliability of more recently developed Stroop variants such as emotional Stroop tasks to standard versions of the Stroop. The current study developed four different single-stimulus Stroop tasks and compared test-retest…
ERIC Educational Resources Information Center
Mchenry, Nadine; Borger, Laurie; Liable-Sands, Louise
2017-01-01
The current study was constructed based on the recommendations of a previous study (McHenry & Borger, 2013). Though inquiry-based teaching has long been touted as an effective pedagogy, its application by middle school science teachers has been problematic. Using tools developed from the previous study in conjunction with professional…
ERIC Educational Resources Information Center
Jessup, Michael Hyle
This study is concerned with the historical development of certain areas of university extension--credit and noncredit courses, correspondence study, and conferences, institutes, and short courses--which appear widespread and important in current extension programs. Credit and noncredit courses and correspondence study were among the earliest…
ERIC Educational Resources Information Center
Tangsri, Chatcai; Na-Takuatoong, Onjaree; Sophatsathit, Peraphon
2013-01-01
This article aims to show how the process of new service technology-based development improves the current study support service for visually impaired university students. Numerous studies have contributed to improving assisted aid technology such as screen readers, the development and the use of audiobooks, and technology that supports individual…
ERIC Educational Resources Information Center
Vandenbroucke, Loren; Spilt, Jantine; Verschueren, Karine; Piccinin, Claire; Baeyens, Dieter
2018-01-01
Executive functions (EFs), important cognitive processes that enable goal-directed behavior, develop due to maturation and environmental stimulation. The current study systematically reviews and synthesizes evidence on the association between teacher-student interactions and EFs. The search resulted in 28 studies, from which 23 studies provided…
Developing the Mathematics Learning Management Model for Improving Creative Thinking in Thailand
ERIC Educational Resources Information Center
Sriwongchai, Arunee; Jantharajit, Nirat; Chookhampaeng, Sumalee
2015-01-01
The study purposes were: 1) To study current states and problems of relevant secondary students in developing mathematics learning management model for improving creative thinking, 2) To evaluate the effectiveness of model about: a) efficiency of learning process, b) comparisons of pretest and posttest on creative thinking and achievement of…
Morphology and Spelling in Arabic: Development and Interface
ERIC Educational Resources Information Center
Taha, Haitham; Saiegh-Haddad, Elinor
2017-01-01
In the current study, two experiments were carried out: the first tested the development of derivational root and word-pattern morphological awareness in Arabic; the second tested morphological processing in Arabic spelling. 143 Arabic native speaking children with normal reading skills in 2nd, 4th and 6th grade participated in the study. The…
Case Study: Use of Problem-Based Learning to Develop Students' Technical and Professional Skills
ERIC Educational Resources Information Center
Warnock, James N.; Mohammadi-Aragh, M. Jean
2016-01-01
Problem-based learning (PBL) is a pedagogy that has attracted attention for many biomedical engineering curricula. The aim of the current study was to address the research question, "Does PBL enable students to develop desirable professional engineering skills?" The desirable skills identified were communication, teamwork, problem…
Coloniality and a Global Testing Regime in Higher Education: Unpacking the OECD's AHELO Initiative
ERIC Educational Resources Information Center
Shahjahan, Riyad A.
2013-01-01
The Organization for Economic Cooperation and Development (OECD) is currently engaging in a worldwide feasibility study entitled International Assessment of Higher Education Learning Outcomes (AHELO). This feasibility study seeks to develop measures that would assess student learning outcomes that would be valid across different languages,…
Development of Multisensory Spatial Integration and Perception in Humans
ERIC Educational Resources Information Center
Neil, Patricia A.; Chee-Ruiter, Christine; Scheier, Christian; Lewkowicz, David J.; Shimojo, Shinsuke
2006-01-01
Previous studies have shown that adults respond faster and more reliably to bimodal compared to unimodal localization cues. The current study investigated for the first time the development of audiovisual (A-V) integration in spatial localization behavior in infants between 1 and 10 months of age. We observed infants' head and eye movements in…
Microfiche Storage and Retrieval System Study: Final Report.
ERIC Educational Resources Information Center
Wicker, Roger; And Others
System Development Corporation's (SDC) exploration of microform state-of-the-art and current research reveals developments which will be applicable to the requirements of many small Department of Defense (DoD) users and similar facilities in the next two to five years. The study's survey of the small user population reveals a variety of user…
The Development of Verbal and Visual Working Memory Processes: A Latent Variable Approach
ERIC Educational Resources Information Center
Koppenol-Gonzalez, Gabriela V.; Bouwmeester, Samantha; Vermunt, Jeroen K.
2012-01-01
Working memory (WM) processing in children has been studied with different approaches, focusing on either the organizational structure of WM processing during development (factor analytic) or the influence of different task conditions on WM processing (experimental). The current study combined both approaches, aiming to distinguish verbal and…
1980/1981 Decision-Making Casebook for Business and Economics.
ERIC Educational Resources Information Center
Tedesco, Paul H., Ed.; And Others
These teacher developed case studies taken from the business world are presented to help secondary students develop an understanding of economics and of the decision-making process. The studies describe real business situations. All historical and current facts are provided, and students must analyze the data and make business decisions. Teacher…
DOT National Transportation Integrated Search
1976-09-01
The present report discusses the development, implementation, and current status of the Short Term Rehabilitation (STR) Study initiates by the NHTSA in 1974. Experimental designs employed by each of the 11 ASAP/STR sites for the assignment of mid-ran...
ERIC Educational Resources Information Center
Chou, Miao-Chun; Chou, Wen-Jiun; Chiang, Huey-Ling; Wu, Yu-Yu; Lee, Ju-Chin; Wong, Ching-Ching; Gau, Susan Shur-Fen
2012-01-01
The current study compared the sleep schedules, sleep problems among children with autism, their siblings and typically developing children, and to explore other associated factors with sleep problems. We conducted a case-control study consisting 110 children with autistic disorder, 125 unaffected siblings, and 110 age-, sex-, and parental…
Language Learning of Children with Typical Development Using a Deductive Metalinguistic Procedure
ERIC Educational Resources Information Center
Finestack, Lizbeth H.
2014-01-01
Purpose: In the current study, the author aimed to determine whether 4- to 6-year-old typically developing children possess requisite problem-solving and language abilities to produce, generalize, and retain a novel verb inflection when taught using an explicit, deductive teaching procedure. Method: Study participants included a cross-sectional…
Investigating Students' Perceptions of Graduate Learning Outcomes in Mathematics
ERIC Educational Resources Information Center
King, Deborah; Varsavsky, Cristina; Belward, Shaun; Matthews, Kelly
2017-01-01
The purpose of this study is to explore the perceptions mathematics students have of the knowledge and skills they develop throughout their programme of study. It addresses current concerns about the employability of mathematics graduates by contributing much needed insight into how degree programmes are developing broader learning outcomes for…
GIRLSS: A Study of the Effectiveness of a Multi-Modal Intervention to Reduce Relational Aggression
ERIC Educational Resources Information Center
Splett, Joni Williams
2012-01-01
Relational aggression has quickly become a serious issue in schools. In response, school professionals have sought and developed interventions despite a dearth of empirical examination and support. The current study bolsters this area by examining the initial efficacy of GIRLSS, an intervention developed over multiple iterations incorporating the…
Scale Development: Heterosexist Attitudes in Women's Collegiate Athletics
ERIC Educational Resources Information Center
Mullin, Elizabeth M.
2013-01-01
Homophobia and heterosexism in women's athletics have been studied extensively using a qualitative approach. Limited research from a quantitative approach has been conducted in the area and none with a sport-specific instrument. The purpose of the current study was to develop a valid and reliable questionnaire to measure heterosexist attitudes in…
Economic Development Threatens Groundwater in Puerto Rico: Results of a Field Study.
ERIC Educational Resources Information Center
Arbona, Sonia I.; Hunter, John M.
1995-01-01
Presents the results of a field study done on 7 wells providing 37% of the total aquifer production for 4 municipalities in Puerto Rico. Each sampled well showed signs of contamination by heavy metals, nitrate, and semivolatile organic compounds. Although found in low concentrations, current development threatens groundwater quality. (MJP)
2015-02-01
study developed a test plan to test BU16 in CG boats, assessing boat performance, and the modifications required to use the fuel. The third study (and...current project) executed this test plan to quantify implementation issues, benefits and impacts of using the alternative fuel in CG boats under...4 2.2 Project 2: Test Plan Development
ERIC Educational Resources Information Center
Driscoll, Amy
In 1983, the National Institute of Education funded the Far West Laboratory for Educational Research and Development to conduct a study, Applying Research to Teacher Education (ARTE) Research Utilization in Elementary Teacher Education (RUETE). The ARTE:RUETE study's purpose is to develop preservice instruction incorporating current research…
[How to integrate humanization and technology in nursing training].
Meyer, Dagmar Estermann
2002-01-01
This paper discusses the current incorporation of the subject of humanization of care in the current context of Brazilian nursing. The relation between nursing and technology is approached, in this study, from a historical perspective. The study also develops the proposition of "human re-signification", having as reference the concept of Cyborg, considering the way this concept has been employed in the contemporary cultural and feminist theoretical framework.
Air Force Geophysics Laboratory Management Information System Study.
1985-11-01
management information system (MIS) at AFGL. The study summarizes current management and administrative practices at AFGL. Requirements have been identified for automating several currently manual functions to compile accurate and timely information to better manage and plan AFGL programs. This document describes the functions and relative priorities of five MIS subsystems and provides suggestions for implementation solutions. Creation of a detailed Development Plan is recommended as the follow-on task.
NASA Astrophysics Data System (ADS)
Zhang, D.; Lee, T.; Wang, F.; McPhaden, M. J.; Kessler, W. S.
2016-12-01
Meridional thermocline currents play an important role in the recharge and discharge of tropical Pacific warm water during the development and transition of ENSO cycles. Previous analyses have shown large variations of the equatorward meridional thermocline convergence/divergence on ENSO and decadal time scales in the interior ocean. The total convergence/divergence is however unknown due to the lack of long term observation in the western boundary currents. Numerical modelling studies suggested a tendency of compensation between the interior and western boundary currents, but the exact compensation is model dependent. While Argo floats provide reasonable data coverage in the interior ocean, few floats are in the western boundary currents. Recent multi-mission satellite altimeter data and advanced processing techniques have resulted in higher resolution sea surface height anomaly (SSHA) products with better accuracy closer to the coasts. This study utilizes the statistical relationship between Argo dynamic height profiles and altimeter SSHA to calculate geostrophic thermocline currents in both the interior ocean and the western boundary of the tropical Pacific. The derived thermocline currents in the western boundary are validated by a 3.5-year moored Acoustic Doppler Current Profiler (ADCP) measurement in the Mindanao Current and by a series of glider surveys (Davis et al. 2012) in the Solomon Sea. The meridional transport timeseries of the interior and western boundary currents in the thermocline show different lead-lag relationships to the Nino 3.4 index. Results will be discussed in the context of recent 2014-2015 El Nino development and the potential contribution to the Tropical Pacific Observing System (TPOS).
Bisogno, G; Ferrari, A; Bien, E; Brecht, I B; Brennan, B; Cecchetto, G; Godzinski, J; Orbach, D; Reguerre, Y; Stachowicz-Stencel, T; Schneider, D T
2012-10-01
The low incidence and the heterogeneity of very rare tumors (VRTs) demand for international cooperation. In 2008, EXPeRT (European Cooperative Study Group for Pediatric Rare Tumors) was founded by national groups from Italy, France, United Kingdom, Poland and Germany. The first aims of EXPeRT were to agree on a uniform definition of VRTs and to develop the currently most relevant scientific questions. Current initiatives include international data exchange, retrospective and prospective studies of specific entities, and the development of harmonized and internationally recognized guidelines. Moreover, EXPeRT established a network for expert consultation to assist in clinical decision in VRTs. © Georg Thieme Verlag KG Stuttgart · New York.
Software Toolbox for Low-Frequency Conductivity and Current Density Imaging Using MRI.
Sajib, Saurav Z K; Katoch, Nitish; Kim, Hyung Joong; Kwon, Oh In; Woo, Eung Je
2017-11-01
Low-frequency conductivity and current density imaging using MRI includes magnetic resonance electrical impedance tomography (MREIT), diffusion tensor MREIT (DT-MREIT), conductivity tensor imaging (CTI), and magnetic resonance current density imaging (MRCDI). MRCDI and MREIT provide current density and isotropic conductivity images, respectively, using current-injection phase MRI techniques. DT-MREIT produces anisotropic conductivity tensor images by incorporating diffusion weighted MRI into MREIT. These current-injection techniques are finding clinical applications in diagnostic imaging and also in transcranial direct current stimulation (tDCS), deep brain stimulation (DBS), and electroporation where treatment currents can function as imaging currents. To avoid adverse effects of nerve and muscle stimulations due to injected currents, conductivity tensor imaging (CTI) utilizes B1 mapping and multi-b diffusion weighted MRI to produce low-frequency anisotropic conductivity tensor images without injecting current. This paper describes numerical implementations of several key mathematical functions for conductivity and current density image reconstructions in MRCDI, MREIT, DT-MREIT, and CTI. To facilitate experimental studies of clinical applications, we developed a software toolbox for these low-frequency conductivity and current density imaging methods. This MR-based conductivity imaging (MRCI) toolbox includes 11 toolbox functions which can be used in the MATLAB environment. The MRCI toolbox is available at http://iirc.khu.ac.kr/software.html . Its functions were tested by using several experimental datasets, which are provided together with the toolbox. Users of the toolbox can focus on experimental designs and interpretations of reconstructed images instead of developing their own image reconstruction softwares. We expect more toolbox functions to be added from future research outcomes. Low-frequency conductivity and current density imaging using MRI includes magnetic resonance electrical impedance tomography (MREIT), diffusion tensor MREIT (DT-MREIT), conductivity tensor imaging (CTI), and magnetic resonance current density imaging (MRCDI). MRCDI and MREIT provide current density and isotropic conductivity images, respectively, using current-injection phase MRI techniques. DT-MREIT produces anisotropic conductivity tensor images by incorporating diffusion weighted MRI into MREIT. These current-injection techniques are finding clinical applications in diagnostic imaging and also in transcranial direct current stimulation (tDCS), deep brain stimulation (DBS), and electroporation where treatment currents can function as imaging currents. To avoid adverse effects of nerve and muscle stimulations due to injected currents, conductivity tensor imaging (CTI) utilizes B1 mapping and multi-b diffusion weighted MRI to produce low-frequency anisotropic conductivity tensor images without injecting current. This paper describes numerical implementations of several key mathematical functions for conductivity and current density image reconstructions in MRCDI, MREIT, DT-MREIT, and CTI. To facilitate experimental studies of clinical applications, we developed a software toolbox for these low-frequency conductivity and current density imaging methods. This MR-based conductivity imaging (MRCI) toolbox includes 11 toolbox functions which can be used in the MATLAB environment. The MRCI toolbox is available at http://iirc.khu.ac.kr/software.html . Its functions were tested by using several experimental datasets, which are provided together with the toolbox. Users of the toolbox can focus on experimental designs and interpretations of reconstructed images instead of developing their own image reconstruction softwares. We expect more toolbox functions to be added from future research outcomes.
Monoamine oxidase: Radiotracer chemistry and human studies
DOE Office of Scientific and Technical Information (OSTI.GOV)
Fowler, Joanna S.; Logan, Jean; Shumay, Elena
Monoamine oxidase (MAO) oxidizes amines from both endogenous and exogenous sources thereby regulating the concentration of neurotransmitter amines such as serot onin, norepinephrine and dopamine as well as many xenobiotics. MAO inhibitor drugs are used in the treatment of Parkinson’s disease and in depression stimulating the development of radiotracer tools to probe the role of MAO in normal human biology and in disease. Over the past 30 since the first radiotracers were developed and the first PET images of MAO in humans were carried out, PET studies of brain MAO in healthy volunteers and in patients have identified different variablesmore » which have contributed to different MAO levels in brain and in peripheral organs. MAO radiotracers and PET have also been used to study the current and developing MAO inhibitor drugs including the selection of doses for clinical trials. In this article, we describe (1) the development of MAO radiotracers; (2) human studies including the relationship of brain MAO levels to genotype, personality, neurological and psychiatric disorders; (3) examples of the use of MAO radiotracers in drug research and development. We will conclude with outstanding needs to improve the radiotracers which are currently used and possible new applications.« less
Holmes, Emily A; Ghaderi, Ata; Eriksson, Ellinor; Lauri, Klara Olofsdotter; Kukacka, Olivia M; Mamish, Maya; James, Ella L; Visser, Renée M
2017-03-01
The number of refugees is the highest ever worldwide. Many have experienced trauma in home countries or on their escape which has mental health sequelae. Intrusive memories comprise distressing scenes of trauma which spring to mind unbidden. Development of novel scalable psychological interventions is needed urgently. We propose that brief cognitive science-driven interventions should be developed which pinpoint a focal symptom alongside a means to monitor it using behavioural techniques. The aim of the current study was to assess the feasibility and acceptability of the methodology required to develop such an intervention. In this study we recruited 22 refugees (16-25 years), predominantly from Syria and residing in Sweden. Participants were asked to monitor the frequency of intrusive memories of trauma using a daily diary; rate intrusions and concentration; and complete a 1-session behavioural intervention involving Tetris game-play via smartphone. Frequency of intrusive memories was high, and associated with high levels of distress and impaired concentration. Levels of engagement with study procedures were highly promising. The current work opens the way for developing novel cognitive behavioural approaches for traumatized refugees that are mechanistically derived, freely available and internationally scalable.
Monoamine oxidase: Radiotracer chemistry and human studies
Fowler, Joanna S.; Logan, Jean; Shumay, Elena; ...
2015-03-01
Monoamine oxidase (MAO) oxidizes amines from both endogenous and exogenous sources thereby regulating the concentration of neurotransmitter amines such as serot onin, norepinephrine and dopamine as well as many xenobiotics. MAO inhibitor drugs are used in the treatment of Parkinson’s disease and in depression stimulating the development of radiotracer tools to probe the role of MAO in normal human biology and in disease. Over the past 30 since the first radiotracers were developed and the first PET images of MAO in humans were carried out, PET studies of brain MAO in healthy volunteers and in patients have identified different variablesmore » which have contributed to different MAO levels in brain and in peripheral organs. MAO radiotracers and PET have also been used to study the current and developing MAO inhibitor drugs including the selection of doses for clinical trials. In this article, we describe (1) the development of MAO radiotracers; (2) human studies including the relationship of brain MAO levels to genotype, personality, neurological and psychiatric disorders; (3) examples of the use of MAO radiotracers in drug research and development. We will conclude with outstanding needs to improve the radiotracers which are currently used and possible new applications.« less
NASA Astrophysics Data System (ADS)
Yim, S.-W.; Park, B.-C.; Jeong, Y.-T.; Kim, Y.-J.; Yang, S.-E.; Kim, W.-S.; Kim, H.-R.; Du, H.-I.
2013-01-01
A 22.9 kV class hybrid fault current limiter (FCL) developed by Korea Electric Power Corporation and LS Industrial Systems in 2006 operates using the line commutation mechanism and begins to limit the fault current after the first half-cycle. The first peak of the fault current is available for protective coordination in the power system. However, it also produces a large electromagnetic force and imposes a huge stress on power facilities such as the main transformer and gas-insulated switchgear. In this study, we improved the operational characteristics of the hybrid FCL in order to reduce the first peak of the fault current. While maintaining the structure of the hybrid FCL system, we developed a superconducting module that detects and limits the fault current during the first half-cycle. To maintain the protective coordination capacity, the hybrid FCL was designed to reduce the first peak value of the fault current by up to approximately 30%. The superconducting module was also designed to produce a minimum AC loss, generating a small, uniform magnetic field distribution during normal operation. Performance tests confirmed that when applied to the hybrid FCL, the superconducting module showed successful current limiting operation without any damage.
Elson, Edward
2009-01-01
A theory of control of cellular proliferation and differentiation in the early development of metazoan systems, postulating a system of electrical controls "parallel" to the processes of molecular biochemistry, is presented. It is argued that the processes of molecular biochemistry alone cannot explain how a developing organism defies a stochastic universe. The demonstration of current flow (charge transfer) along the long axis of DNA through the base-pairs (the "pi-way) in vitro raises the question of whether nature may employ such current flows for biological purposes. Such currents might be too small to be accessible to direct measurement in vivo but conduction has been measured in vitro, and the methods might well be extended to living systems. This has not been done because there is no reasonable model which could stimulate experimentation. We suggest several related, but detachable or independent, models for the biological utility of charge transfer, whose scope admittedly outruns current concepts of thinking about organization, growth, and development in eukaryotic, metazoan systems. The ideas are related to explanations proposed to explain the effects demonstrated on tumors and normal tissues described in Article I (this issue). Microscopic and mesoscopic potential fields and currents are well known at sub-cellular, cellular, and organ systems levels. Not only are such phenomena associated with internal cellular membranes in bioenergetics and information flow, but remarkable long-range fields over tissue interfaces and organs appear to play a role in embryonic development (Nuccitelli, 1992 ). The origin of the fields remains unclear and is the subject of active investigation. We are proposing that similar processes could play a vital role at a "sub-microscopic level," at the level of the chromosomes themselves, and could play a role in organizing and directing fundamental processes of growth and development, in parallel with the more discernible fields and currents described.
NASA Technical Reports Server (NTRS)
Wilson, G. R.; Khazanov, G.; Horwitz, J. L.
1997-01-01
In this study we investigate how the condition of zero current on open flux tubes with polar wind outflow, subjected to large photoelectron fluxes, can be achieved. We employ a steady state collisionless semikinetic model to determine the density profiles of O(+), H(+), thermal electrons and photoelectrons coming from the ionosphere along with H(+), ions and electrons coming from the magnetosphere. The model solution attains a potential distribution which both satisfies the condition of charge neutrality and zero current. For the range of parameters considered in this study we find that a 45-60 volt discontinuous potential drop may develop to reflect most of the photoelectrons back toward the ionosphere. This develops because the downward flux of electrons from the magnetosphere to the ionosphere on typical open flux tubes (e.g. the polar rain) appears to be insufficient to balance the photoelectron flux from the ionosphere.
Hulka, J F; Omran, K; Lieberman, B A; Gordon, A G
1979-12-15
Since the original spring clip sterilization studies were reported, a number of clinically important modifications to the spring clip and applicator have been developed. The spring-loaded clip, manufactured by Richard Wolf Medical Instruments Corporation of Chicago, Illinois, and Rocket of London, Inc., London, England, and New York, New York can be applied with either a one- or two-incision applicator and the clips and applicators currently available incorporate improvements to the original prototypes in design, manufacture, and quality control. The two-incision applicator is associated with significantly fewer misapplications and the high pregnancy rates reported with the original clip and applicator have not occurred with the current designs. Comparative studies between the clip and band have revealed less operative bleeding and pain associated with the clip. The method is appropriate to all women requesting sterilization but especially to those in the younger age group who may subsequently request reversal because of divorce and remarriage.
Utilizing Data from Cancer Patient & Survivor Studies
Utilizing Data from Cancer Patient & Survivor Studies and Understanding the Current State of Knowledge and Developing Future Research Priorities, a 2011 workshop sponsored by the Epidemiology and Genomics Research Program.
ERIC Educational Resources Information Center
Abou-Warda, Sherein Hamed
2016-01-01
Purpose: The overall objective of the current study is to explore how universities can better developing new educational services. The purpose of this paper is to develop framework for technology entrepreneurship education (TEPE) within universities. Design/Methodology/Approach: Qualitative and quantitative research approaches were employed. This…
Teacher Collaboration in Curriculum Design Teams: Effects, Mechanisms, and Conditions
ERIC Educational Resources Information Center
Voogt, Joke M.; Pieters, Jules M.; Handelzalts, Adam
2016-01-01
Collaborative design positively affects both professional development and the implementation of curriculum change, because teachers develop competencies and practice and develop ownership of the change. The current study was aimed to explore what empirical evidence is available about processes that take place when teachers co-design and how these…
Language and Literacy: Current Issues and Research.
ERIC Educational Resources Information Center
Gorman, Thomas P., Ed.
Comprising a study of the application of linguistics to literacy, the 16 papers in this book were prepared by contributors from both developing and developed nations. The papers in the first section illustrate the relevance of certain developments in theoretical and applied linguistics, sociolinguistics, and psycholinguistics to literacy teaching.…
ERIC Educational Resources Information Center
Pizzolato, Jane Elizabeth; Nguyen, Tu-Lien Kim; Johnston, Marc P.; Wang, Sherry
2012-01-01
Existing research points toward dissonance as the primary catalyst in self-authorship development. This study investigated the cultural relevance of current conceptions of dissonance's role in self-authorship development. A total of 166 participants of color were recruited from three large public research universities from different regions in the…
Analyzing Principal Professional Development Practices through the Lens of Adult Learning Theory
ERIC Educational Resources Information Center
Zepeda, Sally J.; Parylo, Oksana; Bengtson, Ed
2014-01-01
This qualitative study sought to identify current principal professional development practices in four school systems in Georgia and to examine them by applying the principles of adult learning theory. The cross-case analysis of principal professional development initiatives in four school districts revealed nine common practices: connecting…
ERIC Educational Resources Information Center
Kyndt, Eva; Janssens, Ine; Coertjens, Liesje; Gijbels, David; Donche, Vincent; Van Petegem, Peter
2014-01-01
The current study reports on the process of developing a self-assessment instrument for vocational education students' generic working life competencies. The instrument was developed based on a competence framework and in close collaboration with several vocational education teachers and intermediary organisations offering various human…
Identity Development of Literacy Teachers of Adolescents with Significant Cognitive Disabilities
ERIC Educational Resources Information Center
Roberts, Carly A.
2013-01-01
This study employs the theory of identity development and figured worlds to investigate how historical and current education context, preservice and inservice teacher preparation, and school and classroom context influence the development of the literacy teaching identity of teachers of adolescents with significant cognitive disabilities. A…
Career Development: Theory and Practice.
ERIC Educational Resources Information Center
Montross, David H., Ed.; Shinkman, Christopher J., Ed.
This book explores the latest developments in the theory and practice of career development, as seen by 21 professionals in the field. The study is organized in four parts that cover the following areas: the latest thinking about career theory; the career stages of exploration, establishment, maintenance, and decline; current thinking about the…
Promising Directions for Research and Development in Early Childhood Education.
ERIC Educational Resources Information Center
Elliott, David L.
A survey of research and development studies currently needed in early childhood education stresses child development and its relation to instruction. Topics which have been discussed are perception, oral language, concept formation, learning set, motivation, and the psychology of learning. Universities and public school systems working together…
Concepts for Care: 20 Essays on Infant/Toddler Development and Learning
ERIC Educational Resources Information Center
Lally, J. Ronald, Ed.; Mangione, Peter L., Ed.; Greenwald, Deborah, Ed.
2006-01-01
Leading experts in infant/toddler development have contributed succinct essays drawn from research, theory, clinical case studies, and carefully documented practice. Each essay represents current thinking in the field of infant/toddler development and care. Individually and as a collection, the essays provide a springboard for reflection,…
Evaluating the Structure of Early English Literacy Skills in Deaf and Hard-of-Hearing Children
ERIC Educational Resources Information Center
Webb, Mi-Young; Lederberg, Amy R.; Branum-Martin, Lee; McDonald Connor, Carol
2015-01-01
Better understanding the mechanisms underlying developing literacy has promoted the development of more effective reading interventions for typically developing children. Such knowledge may facilitate effective instruction of deaf and hard-of-hearing (DHH) children. Hence, the current study examined the multivariate associations among phonological…
Courseware Development for Semiconductor Technology and Its Application into Instruction
ERIC Educational Resources Information Center
Tsai, Shu-chiao
2009-01-01
This study reports on the development of ESP (English for specific purposes) courseware for semiconductor technology and its integration as a "silent partner" into instruction. This kind of team-teaching could help overcome current problems encountered in developing ESP in Taiwan. The content of the material under discussion includes…
Taylor, Erin Audrey; Fischer, Shira H; Gracner, Tadeja; Tejeda, Ivo; Kim, Alice; Chavez-Herrerias, Emilio; de la Guardia, Fernando Hoces
2016-06-20
As part of an effort to assist Chile in developing a strategic program to foster the development of the health information technology (health IT) sector over the next five to ten years, this study assesses the current state of health IT adoption and implementation in Chile, as well as the challenges and opportunities facing the sector over the coming years. The authors conducted an environmental scan and ten key informant interviews and found that there are a number of successful health IT projects and strategies for further development currently underway in Chile, but that the successful projects are generally localized within specific health care providers and lack integration. These and other challenges suggest significant potential for the Ministry of Economy and other stakeholders to take specific actions designed to encourage further development of the health IT sector in Chile over the coming years. The next phase of this effort will use the results from this study to develop a roadmap for the Ministry of Economy to encourage health IT development in Chile over the short, medium, and long terms.
BET inhibitors in cancer therapeutics: a patent review.
Ghoshal, Anirban; Yugandhar, D; Srivastava, Ajay Kumar
2016-01-01
Inhibition of Bromodomain and Extra Terminal (BET) proteins is an emerging approach for developing advanced cancer therapeutics. In 2015, at least thirty patents have been published for developing cancer chemotherapeutics by targeting BET. Currently there are seven small molecule BET inhibitors in various stages of clinical trials for the development of anti-cancer drugs. Important patents focusing on development of BET inhibitors as potential cancer therapeutics published in 2015 have been covered. The reports are presented together with a review of the related structural chemical space. This review mainly focuses on the therapeutic applications, chemical class and structural modifications along with the molecules currently in clinical trials. BET sub-family proteins are one of the emerging targets to develop anti-cancer agents. Although many research groups have demonstrated the rationality of BET inhibition to combat cancer, a detailed molecular study needs to be performed to investigate the affected biological pathways. Selectivity among BET proteins should be kept in mind while developing BET inhibitors. In-silico molecular modelling studies can also provide valuable information for designing selective BET inhibitors towards anti-cancer drug discovery and development.
Flanagan, Sarah E; De Franco, Elisa; Lango Allen, Hana; Zerah, Michele; Abdul-Rasoul, Majedah M; Edge, Julie A; Stewart, Helen; Alamiri, Elham; Hussain, Khalid; Wallis, Sam; de Vries, Liat; Rubio-Cabezas, Oscar; Houghton, Jayne A L; Edghill, Emma L; Patch, Ann-Marie; Ellard, Sian; Hattersley, Andrew T
2014-01-07
Understanding transcriptional regulation of pancreatic development is required to advance current efforts in developing beta cell replacement therapies for patients with diabetes. Current knowledge of key transcriptional regulators has predominantly come from mouse studies, with rare, naturally occurring mutations establishing their relevance in man. This study used a combination of homozygosity analysis and Sanger sequencing in 37 consanguineous patients with permanent neonatal diabetes to search for homozygous mutations in 29 transcription factor genes important for murine pancreatic development. We identified homozygous mutations in 7 different genes in 11 unrelated patients and show that NKX2-2 and MNX1 are etiological genes for neonatal diabetes, thus confirming their key role in development of the human pancreas. The similar phenotype of the patients with recessive mutations and mice with inactivation of a transcription factor gene support there being common steps critical for pancreatic development and validate the use of rodent models for beta cell development. Copyright © 2014 The Authors. Published by Elsevier Inc. All rights reserved.
Extended Deterrence: Taking Stock of Current Policy and Updating the Research and PME Agendas
2014-08-01
Conference and Venue The INSS “Extended Deterrence: Taking Stock of Current policy and Updating the Research and PME Agendas” workshop took place...Force Institute for National Security Studies ( INSS ) which is sponsored by the Air Force Strategic Plans and Policy Division (A5XP). Subject...emerging strategic environment? INSS anticipated that the discussion would be influenced by current developments such as: • The Russian incursion
DOE Office of Scientific and Technical Information (OSTI.GOV)
Not Available
1981-06-01
A survey was conducted of ten target study groups and subgroups for Klamath Falls, Oregon, and Susanville, California: local government, current and potential industry at the site, relocators to the site, current and potential financial community, regulators, and current and potential promoters and developers. The results of benchmark attitudinal measurement is presented separately for each target group. A literature review was conducted and Macro-environmental attitudes of a sample of local government and industry personnel at the sites were assessed. An assessment of capabilities was made which involved two measurements. The first was a measurement of a sample of promoters, developers,more » and industrial service companies active at the site to determine infrastructure capabilities required by industry for geothermal plants. The second measurement involved analyzing a sample of industry management in the area and defining their requirements for plant retrofit and expansion. Finally, the processes used by the study group to analyze information to reach commitment and regulatory decisions that significantly impact on geothermal energy projects at the site were identified and defined.« less
High Energy Astrophysics and Cosmology from Space: NASA's Physics of the Cosmos Program
NASA Astrophysics Data System (ADS)
Hornschemeier, Ann
2016-03-01
We summarize currently-funded NASA activities in high energy astrophysics and cosmology, embodied in the NASA Physics of the Cosmos program, including updates on technology development and mission studies. The portfolio includes development of a space mission for measuring gravitational waves from merging supermassive black holes, currently envisioned as a collaboration with the European Space Agency (ESA) on its L3 mission and development of an X-ray observatory that will measure X-ray emission from the final stages of accretion onto black holes, currently envisioned as a NASA collaboration on ESA's Athena observatory. The portfolio also includes the study of cosmic rays and gamma ray photons resulting from a range of processes, of the physical process of inflation associated with the birth of the universe and of the nature of the dark energy that dominates the mass-energy of the modern universe. The program is supported by an analysis group called the PhysPAG that serves as a forum for community input and analysis and the talk will include a description of activities of this group.
Laser Communication Demonstration System (LCDS) and future mobile satellite services
NASA Technical Reports Server (NTRS)
Chen, Chien-Chung; Wilhelm, Michael D.; Lesh, James R.
1995-01-01
The Laser Communications Demonstration System (LCDS) is a proposed in-orbit demonstration of high data rate laser communications technology conceived jointly by NASA and U.S. industry. The program objectives are to stimulate industry development and to demonstrate the readiness of high data rate optical communications in Earth orbit. For future global satellite communication systems using intersatellite links, laser communications technology can offer reduced mass and power requirements and higher channel bandwidths without regulatory constraints. As currently envisioned, LCDS will consist of one or two orbiting laser communications terminals capable of demonstrating high data rate (greater than 750Mbps) transmission in a dynamic space environment. Two study teams led by Motorola and Ball Aerospace are currently in the process of conducting a Phase A/B mission definition study of LCDS under contracts with JPL/NASA. The studies consist of future application survey, concept and requirements definition, and a point design of the laser communications flight demonstration. It is planned that a single demonstration system will be developed based on the study results. The Phase A/B study is expected to be completed by the coming June, and the current results of the study are presented in this paper.
Guidelines for the Design and Conduct of Clinical Studies in Knee Articular Cartilage Repair
Mithoefer, Kai; Saris, Daniel B.F.; Farr, Jack; Kon, Elizaveta; Zaslav, Kenneth; Cole, Brian J.; Ranstam, Jonas; Yao, Jian; Shive, Matthew; Levine, David; Dalemans, Wilfried; Brittberg, Mats
2011-01-01
Objective: To summarize current clinical research practice and develop methodological standards for objective scientific evaluation of knee cartilage repair procedures and products. Design: A comprehensive literature review was performed of high-level original studies providing information relevant for the design of clinical studies on articular cartilage repair in the knee. Analysis of cartilage repair publications and synopses of ongoing trials were used to identify important criteria for the design, reporting, and interpretation of studies in this field. Results: Current literature reflects the methodological limitations of the scientific evidence available for articular cartilage repair. However, clinical trial databases of ongoing trials document a trend suggesting improved study designs and clinical evaluation methodology. Based on the current scientific information and standards of clinical care, detailed methodological recommendations were developed for the statistical study design, patient recruitment, control group considerations, study endpoint definition, documentation of results, use of validated patient-reported outcome instruments, and inclusion and exclusion criteria for the design and conduct of scientifically sound cartilage repair study protocols. A consensus statement among the International Cartilage Repair Society (ICRS) and contributing authors experienced in clinical trial design and implementation was achieved. Conclusions: High-quality clinical research methodology is critical for the optimal evaluation of current and new cartilage repair technologies. In addition to generally applicable principles for orthopedic study design, specific criteria and considerations apply to cartilage repair studies. Systematic application of these criteria and considerations can facilitate study designs that are scientifically rigorous, ethical, practical, and appropriate for the question(s) being addressed in any given cartilage repair research project. PMID:26069574
Delayed-onset endophthalmitis associated with corneal suture infections.
Henry, Christopher R; Flynn, Harry W; Miller, Darlene; Schefler, Amy C; Forster, Richard K; Alfonso, Eduardo C
2013-06-11
The purpose of the current study was to report the microbiology, risk factors, and treatment outcomes in patients with delayed-onset endophthalmitis associated with corneal suture infections. For this retrospective consecutive case series, a search of the ocular microbiology department database was performed to identify all patients with positive corneal and intraocular cultures (anterior chamber and/or vitreous) between 01 January 1995 and 01 January 2010. A subset of patients with a history of corneal suture infections and delayed-onset endophthalmitis was identified. Over the 15-year period of the study, 68 patients were identified to have both positive corneal and intraocular cultures. Among them, six patients were identified to have a culture-proven, delayed-onset endophthalmitis that developed from a culture-positive corneal suture infection. All of the patients in the current study were using topical corticosteroids at the time of diagnosis. In four of six patients, there was documented manipulation of a suture before the development of endophthalmitis. Streptoccocus was identified as the causative organism in five of six patients in the current study. All of the Streptoccocus isolates were sensitive to vancomycin. The single case of Serratia marcescens endophthalmitis was sensitive to amikacin, ceftazidime, ciprofloxacin, gentamicin, and tobramycin. Treatment modalities varied and were guided by the attending ophthalmologist depending upon clinical presentation. One patient with severe Streptococcus pyogenes keratitis and endophthalmitis underwent a primary enucleation after developing a wound dehiscence. Of the remaining five patients, all received topical and intravitreal antibiotics. Therapeutic penetrating keratoplasty was performed in three patients. Pars plana vitrectomy was performed in two patients. Visual acuity outcomes ranged from 20/150 to no light perception. In the current study, Streptococcus was isolated in nearly all patients with delayed-onset endophthalmitis associated with corneal suture infections. Topical steroid use and suture manipulation were identified as associated factors for developing endophthalmitis. Visual acuity outcomes were poor despite the prompt recognition of endophthalmitis and appropriate antibiotic therapy.
An alternative approach for socio-hydrology: case study research
NASA Astrophysics Data System (ADS)
Mostert, Erik
2018-01-01
Currently the most popular approach in socio hydrology is to develop coupled human-water models. This article proposes an alternative approach, qualitative case study research, involving a systematic review of (1) the human activities affecting the hydrology in the case, (2) the main human actors, and (3) the main factors influencing the actors and their activities. Moreover, this article presents a case study of the Dommel Basin in Belgium and the Netherlands, and compares this with a coupled model of the Kissimmee Basin in Florida. In both basins a pendulum swing
from water resources development and control to protection and restoration can be observed. The Dommel case study moreover points to the importance of institutional and financial arrangements, community values, and broader social, economic, and technical developments. These factors are missing from the Kissimmee model. Generally, case studies can result in a more complete understanding of individual cases than coupled models, and if the cases are selected carefully and compared with previous studies, it is possible to generalize on the basis of them. Case studies also offer more levers for management and facilitate interdisciplinary cooperation. Coupled models, on the other hand, can be used to generate possible explanations of past developments and quantitative scenarios for future developments. The article concludes that, given the limited attention they currently get and their potential benefits, case studies deserve more attention in socio-hydrology.
Challenges and future in vaccines, drug development, and immunomodulatory therapy.
Kling, Heather M; Nau, Gerard J; Ross, Ted M; Evans, Thomas G; Chakraborty, Krishnendu; Empey, Kerry M; Flynn, JoAnne L
2014-08-01
Pulmonary diseases and infections are among the top contributors to human morbidity and mortality worldwide, and despite the successful history of vaccines and antimicrobial therapeutics, infectious disease still presents a significant threat to human health. Effective vaccines are frequently unavailable in developing countries, and successful vaccines have yet to be developed for major global maladies, such as tuberculosis. Furthermore, antibiotic resistance poses a growing threat to human health. The "Challenges and Future in Vaccines, Drug Development, and Immunomodulatory Therapy" session of the 2013 Pittsburgh International Lung Conference highlighted several recent and current studies related to treatment and prevention of antibiotic-resistant bacterial infections, highly pathogenic influenza, respiratory syncytial virus, and tuberculosis. Research presented here focused on novel antimicrobial therapies, new vaccines that are either in development or currently in clinical trials, and the potential for immunomodulatory therapies. These studies are making important contributions to the areas of microbiology, virology, and immunology related to pulmonary diseases and infections and are paving the way for improvements in the efficacy of vaccines and antimicrobials.
a Web Api and Web Application Development for Dissemination of Air Quality Information
NASA Astrophysics Data System (ADS)
Şahin, K.; Işıkdağ, U.
2017-11-01
Various studies have been carried out since 2005 under the leadership of Ministry of Environment and Urbanism of Turkey, in order to observe the quality of air in Turkey, to develop new policies and to develop a sustainable air quality management strategy. For this reason, a national air quality monitoring network has been developed providing air quality indices. By this network, the quality of the air has been continuously monitored and an important information system has been constructed in order to take precautions for preventing a dangerous situation. The biggest handicap in the network is the data access problem for instant and time series data acquisition and processing because of its proprietary structure. Currently, there is no service offered by the current air quality monitoring system for exchanging information with third party applications. Within the context of this work, a web service has been developed to enable location based querying of the current/past air quality data in Turkey. This web service is equipped with up-todate and widely preferred technologies. In other words, an architecture is chosen in which applications can easily integrate. In the second phase of the study, a web-based application was developed to test the developed web service and this testing application can perform location based acquisition of air-quality data. This makes it possible to easily carry out operations such as screening and examination of the area in the given time-frame which cannot be done with the national monitoring network.
Student Stalking of Faculty: Potential Gaps in Campus Faculty Development Efforts
ERIC Educational Resources Information Center
Morgan, Robin K.; Hunter, Sarah; Bertrand, Abigail
2013-01-01
Centers for teaching and learning (CTLs) provide much of the faculty development in universities across the nation. Many of these centers developed out of a need for enhanced faculty development in technology areas. Fifty CTLs provided data in the current study. Types of programs offered by each center were identified, with specific attention…
A Study on Kinmen Resident's Perception of Tourism Development and Culture Heritage Impact
ERIC Educational Resources Information Center
Wang, Yi-Ping
2016-01-01
Tourism development could drive the enhancement of national income and the demands for international tourism that tourism benefits have become the key source of national revenue. The integration of cultural relics with tourism development to drive the national or regional development has currently become the world trend. Making good use of the…
Perspectives on hypersonic viscous flow research
NASA Technical Reports Server (NTRS)
Cheng, H. K.
1993-01-01
Issues and advances in current hypersonic flow research perceived to be of interest in theoretical fluid/gas dynamics are reviewed. Particular attention is given to the hypersonic aircraft as waverider, computational methods and theoretical development in the study of viscous interaction, and boundary-layer instability and transition studies. In the present framework the study of viscous hypersonic flow faces transition problems of two kinds which represent the two major areas of current research: the turbulence transition in the high Re range and the transition to the free-molecule limit.
Chemical properties of the transactinide elements studied inliquid phase with SISAK
DOE Office of Scientific and Technical Information (OSTI.GOV)
Omtvedt, J.P.; Alstad, J.; Bjornstad, T.
2007-05-01
This article starts with a review of the current SISAKliquid-liquid extraction system, as used after the physical preseparatorBGS at LBNL for chemical studies of transactinide elements. Emphasis willbe on new additions and developments. Then the possibilities offered bythe new TASCA separator at GSI and the use of actinide targets at bothGSI and LBNL are discussed with respect to future SISAK transactinideexperiments. Finally, current and future liquid-liquid extraction systemsfor studying elements Rf up to Hs are discussed.
The role of nutrition in children's neurocognitive development, from pregnancy through childhood
Nyaradi, Anett; Li, Jianghong; Hickling, Siobhan; Foster, Jonathan; Oddy, Wendy H.
2013-01-01
This review examines the current evidence for a possible connection between nutritional intake (including micronutrients and whole diet) and neurocognitive development in childhood. Earlier studies which have investigated the association between nutrition and cognitive development have focused on individual micronutrients, including omega-3 fatty acids, vitamin B12, folic acid, choline, iron, iodine, and zinc, and single aspects of diet. The research evidence from observational studies suggests that micronutrients may play an important role in the cognitive development of children. However, the results of intervention trials utilizing single micronutrients are inconclusive. More generally, there is evidence that malnutrition can impair cognitive development, whilst breastfeeding appears to be beneficial for cognition. Eating breakfast is also beneficial for cognition. In contrast, there is currently inconclusive evidence regarding the association between obesity and cognition. Since individuals consume combinations of foods, more recently researchers have become interested in the cognitive impact of diet as a composite measure. Only a few studies to date have investigated the associations between dietary patterns and cognitive development. In future research, more well designed intervention trials are needed, with special consideration given to the interactive effects of nutrients. PMID:23532379
Ewuoso, Cornelius
2017-09-29
Empirical studies have now established that many patients make clinical decisions based on models other than Anglo American model of truth-telling and patient autonomy. Some scholars also add that current medical ethics frameworks and recent proposals for enhancing communication in health professional-patient relationship have not adequately accommodated these models. In certain clinical contexts where health professional and patients are motivated by significant cultural and religious values, these current frameworks cannot prevent communication breakdown, which can, in turn, jeopardize patient care, cause undue distress to a patient in certain clinical contexts or negatively impact his/her relationship with the community. These empirical studies have now recommended that additional frameworks developed around other models of truth-telling; and which take very seriously significant value-differences which sometimes exist between health professional and patients, as well as patient's cultural/religious values or relational capacities, must be developed. This paper contributes towards the development of one. Specifically, this study proposes a framework for truth-telling developed around African model of truth-telling by drawing insights from the communitarian concept of ootọ́ amongst the Yoruba people of south west Nigeria. I am optimistic that if this model is incorporated into current medical ethics codes and curricula, it will significantly enhance health professional-patient communication. © 2017 John Wiley & Sons Ltd.
Zhao, Junfeng; Li, Xiaoming; Barnett, Douglas; Lin, Xiuyun; Fang, Xiaoyi; Zhao, Guoxiang; Naar-King, Sylvie; Stanton, Bonita
2011-08-01
The objective of this study was to examine the relationship between parental loss, trusting relationship with current caregivers, and psychosocial adjustment among children affected by AIDS in China. In this study, cross-sectional data were collected from 755 AIDS orphans (296 double orphans and 459 single orphans), 466 vulnerable children living with HIV-infected parents, and 404 comparison children in China. The trusting relationship with current caregivers was measured with a 15-item scale (Cronbach's α = 0.84) modified from the Trusting Relationship Questionnaire developed by Mustillo et al. in 2005 (Quality of relationships between youth and community service providers: Reliability and validity of the trusting relationship questionnaire. Journal of Child and Family Studies, 14, 577-590). The psychosocial measures include rule compliance/acting out, anxiety/withdrawal, peer social skills, school interest, depressive symptoms, loneliness, self-esteem, future expectation, hopefulness about future, and perceived control over the future. Group mean comparisons using analysis of variance suggested a significant association (p < 0.0001) between the trusting relationship with current caregivers and all the psychosocial measures, except anxiety and depression. These associations remained significant in General Linear Model analysis, controlling for children's gender, age, family socioeconomic status, orphan status (orphans, vulnerable children, and comparison children), and appropriate interaction terms among factor variables. The findings in the current study support the global literature on the importance of attachment relationship with caregivers in promoting children's psychosocial development. Future prevention intervention efforts to improve AIDS orphans' psychosocial well-being will need to take into consideration the quality of the child's attachment relationships with current caregivers and help their current caregivers to improve the quality of care for these children. Future study is needed to explore the possible reasons for the lack of association between a trusting relationship and some internalizing symptoms such as anxiety and depression among children affected by HIV/AIDS.
Detection of rip current using camera monitoring techniques
NASA Astrophysics Data System (ADS)
Kim, T.
2016-02-01
Rip currents are approximately shore normal seaward flows which are strong, localized and rather narrow. They are known that stacked water by longshore currents suddenly flow back out to sea as rip currents. They are transient phenomena and their generation time and location are unpredictable. They are also doing significant roles for offshore sediment transport and beach erosion. Rip currents can be very hazardous to swimmers or floaters because of their strong seaward flows and sudden depth changes by narrow and strong flows. Because of its importance in terms of safety, shoreline evolution and pollutant transport, a number of studies have been attempted to find out their mechanisms. However, understanding of rip currents is still not enough to make warning to people in the water by predicting their location and time. This paper investigates the development of rip currents using camera images. Since rip currents are developed by longshore currents, the observed longshore current variations in space and time can be used to detect rip current generation. Most of the time convergence of two longshore currents in the opposite direction is the outbreak of rip current. In order to observe longshore currents, an optical current meter(OCM) technique proposed by Chickadel et al.(2003) is used. The relationship between rip current generation time and longshore current velocity variation observed by OCM is analyzed from the images taken on the shore. The direct measurement of rip current velocity is also tested using image analysis techniques. Quantitative estimation of rip current strength is also conducted by using average and variance image of rip current area. These efforts will contribute to reduce the hazards of swimmers by prediction and warning of rip current generation.
ERIC Educational Resources Information Center
Monographs of the Society for Research in Child Development, 2008
2008-01-01
This study represents a quasi-experimental test of the role of early social-emotional experience and adult-child relationships in the development of typically developing children and those with disabilities birth to 4 years of age living in orphanages in St. Petersburg, Russian Federation. The three orphanages in the current study were selected…
NASA Astrophysics Data System (ADS)
Andreucci, Stefano; Pistis, Marco; Funedda, Antonio; Loi, Alfredo
2017-11-01
The Chattian-Aquitanian carbonate system of Isili sub-basin (SE Sardinia, Italy) were studied to better understand the hydrodynamic processes controlling the formation of landward-downlapping, rhodolith-rich, giant clinoforms. The studied flat-topped platform was attached to an island (semi-isolated) and migrated onshore (landward) over a shallow marine, protected embayment. The depositional profile is characterized by four, sea to land, zones: seaward slope, flat-topped platform (submerged flat), landward slope and mixed siliciclastic-carbonate embayment. In particular, these zones record different levels, from high to moderate, of hydrodynamic energy and persistency. The paleodepth of the studied succession, based on T/D test on Amphistegina specimens, red-algal genera and geometric reconstruction of the overall system, ranges from - 10 to - 30 m for the platform up to around - 40 m for the landward slope base. Thus, the flat-topped platform was permanently submerged and an extensive carbonate (sea grass, algal and bryozoan-algal) factory along with oyster framestones developed. The widespread presence in the barren zones of rhodolith-to-shell rich small to very small compound dunes (high-energy zone) suggests that the flat-topped platform was periodically swept by unidirectional, landward-directed currents. These currents allow the formation of large-scale, rhodolith-rich clinobeds along the landward slope (washover fan-like system). The presence of rodolith pavements developed along the flat-topped platform at or slightly below the fairweather wave base suggests that clinobeds were formed in a nearshore, shallow subtidal setting. Finally, the shallow marine, protected embayment (moderate-energy zone) represents the widening distal reaches of the currents flowing or along the clinoforms or from the coast basinward (river floods and/or ebb tidal currents). Despite few tidal-related sedimentary structures such as bi-directional ripples and small compound dunes separated by finer-grained ;drapes; or reactivation surfaces were observed, the prevailing processes acting over the platform are unidirectional, landward-directed currents possibly associated with longshore currents and/or wave actions. However, the resultant migration of the whole system onshore (landward) cannot be easily explained with storm or wind-related processes. Thus the studied flat-topped platform seems to be controlled by long term tidal regulation within a meso to macro tidal regime. In particular, such meso/macro tidal environments experience multiannual to multidecennial phases of stronger/weaker tidal range fluctuations resembling periods of relatively sea highs and lows with respect to the mean sea level (0 m). All the (wind, storm, wave and tidal) currents sweeping the flat-topped platform were maxima during phases of strong tidal fluctuations generating erosion and sediment transportation over the flat and accumulation on the landward slope (clinobeds). Conversely, during phases of weaker tidal range fluctuations overall currents were minima, clinoforms did not develop and factories widespread re-colonized the submerged flat. Therefore, the studied platform developed in a current-dominated and tidal modulated setting. Finally, the studied carbonates of Sardinia suggest that the Sardinian seaway and the incipient Provençal basin during the Chattian-Aquitanian were, locally, capable to generate meso to macro tidal conditions.
Counterfactual Thinking and False Belief: The Role of Executive Function
ERIC Educational Resources Information Center
Drayton, Stefane; Turley-Ames, Kandi J.; Guajardo, Nicole R.
2011-01-01
The purpose of the current study was to examine further the relationship between counterfactual thinking and false belief (FB) as examined by Guajardo and Turley-Ames ("Cognitive Development, 19" (2004) 53-80). More specifically, the current research examined the importance of working memory and inhibitory control in understanding the relationship…
Current Developments in Community College Performance Funding
ERIC Educational Resources Information Center
D'Amico, Mark M.; Friedel, Janice N.; Katsinas, Stephen G.; Thornton, Zoë M.
2014-01-01
Since the initiation of performance funding in Tennessee in the late 1970s, approximately 30 states have, at some point, attempted a funding model that includes performance on a set of indicators. The purpose of the present study was to capture the current status of performance funding in public statewide community college systems and to assess…
The Tense Situation of Slavic: Past, Present, Future.
ERIC Educational Resources Information Center
Cooper, Henry R., Jr.
1998-01-01
Discusses the challenges and difficulties of Slavic languages, a field that is notoriously cyclical and is currently at the bottom of a cycle. The article chronicles the history of Slavic studies in relation to political developments since World War II, draws parallels between current trends in Slavic and other modern language programs, and sees…
DOT National Transportation Integrated Search
1994-12-01
The objectives of this study were to: 1) estimate the situation in year 2005 with the current TIMED program in operation, 2) estimate how long current TIMED funding must be extended to fully fund the projects listed in the TIMED program, and 3) estim...
Complete Statistical Survey Results of 1982 Texas Competency Validation Project.
ERIC Educational Resources Information Center
Rogers, Sandra K.; Dahlberg, Maurine F.
This report documents a project to develop current statewide validated competencies for auto mechanics, diesel mechanics, welding, office occupations, and printing. Section 1 describes the four steps used in the current competency validation project and provides a standardized process for conducting future studies at the local or statewide level.…
Current and Future Effects of Mexican Immigration in California. Executive Summary. R-3365/1-CR.
ERIC Educational Resources Information Center
McCarthy, Kevin F.; Valdez, R. Burciaga
This study to assess the current situation of Mexican immigrants in California and project future possibilities constructs a demographic profile of the immigrants, examines their economic effects on the state, and describes their socioeconomic integration into California society. Models of immigration/integration processes are developed and used…
Appropriate utilization of data from toxicogenomic studies ins an ongoing concern of the regulated industries and the agencies charged with assessing safety or risk. An area of current interest is the possibility of toxicogenomics to enhance our ability to develop higher or high-...
Project Icarus: Nuclear Fusion Propulsion Concept Comparison
NASA Astrophysics Data System (ADS)
Stanic, M.
Project Icarus will use nuclear fusion as the primary propulsion, since achieving breakeven is imminent within the next decade. Therefore, fusion technology provides confidence in further development and fairly high technological maturity by the time the Icarus mission would be plausible. Currently there are numerous (over 2 dozen) different fusion approaches that are simultaneously being developed around the World and it is difficult to predict which of the concepts is going to be the most successful one. This study tried to estimate current technological maturity and possible technological extrapolation of fusion approaches for which appropriate data could be found. Figures of merit that were assessed include: current technological state, mass and volume estimates, possible gain values, main advantages and disadvantages of the concept and an attempt to extrapolate current technological state for the next decade or two. Analysis suggests that Magnetic Confinement Fusion (MCF) concepts are not likely to deliver sufficient performance due to size, mass, gain and large technological barriers of the concept. However, ICF and PJMIF did show potential for delivering necessary performance, assuming appropriate techno- logical advances. This paper is a submission of the Project Icarus Study Group.
Welfare of apes in captive environments: comments on, and by, a specific group of apes.
Savage-Rumbaugh, Sue; Wamba, Kanzi; Wamba, Panbanisha; Wamba, Nyota
2007-01-01
Accurately determining the proper captive environment for apes requires adequately assessing the psychological similarities between apes and humans. Scientists currently believe apes lack mental complexity (Millikan, 2006), raising questions concerning the evolution of human culture from ape-like societies (Tomasello, 1999). A long-term cultural study with bonobos suggests less intellectual divergence from humans than currently postulated (Savage-Rumbaugh, 2005). Because humans view apes as mentally limited, some current captive environments may appear idyllic while offering only an illusion of appropriate care, derived from a simplistic view of what apes are, rather than what they might be. This perception of apes determines their handling, which determines their mental development, which perpetuates the prevailing perception. Only breaking this cycle will allow the current perception of apes to change. Their usual captive environment limits any demonstration of culture. However, the bonobo study reveals what ape culture can become, which should affect future welfare considerations for at least those species genetically close to humans (bonobos and chimpanzees). Development of a languaged bonobo culture allows these nonhuman animals to provide their own responses regarding adequate ape welfare.
Effects of current on droplet generation and arc plasma in gas metal arc welding
DOE Office of Scientific and Technical Information (OSTI.GOV)
Hu, J.; Tsai, H. L.
2006-09-01
In gas metal arc welding (GMAW), a technology using pulsed currents has been employed to achieve the one-droplet-per-pulse (ODPP) metal transfer mode with the advantages of low average currents, a stable and controllable droplet generation, and reduced spatter. In this paper, a comprehensive model was developed to study the effects of different current profiles on the droplet formation, plasma generation, metal transfer, and weld pool dynamics in GMAW. Five types of welding currents were studied, including two constant currents and three wave form currents. In each type, the transient temperature and velocity distributions of the arc plasma and the moltenmore » metal, and the shapes of the droplet and the weld pool were calculated. The results showed that a higher current generates smaller droplets, higher droplet frequency, and higher electromagnetic force that becomes the dominant factor detaching the droplet from the electrode tip. The model has demonstrated that a stable ODPP metal transfer mode can be achieved by choosing a current with proper wave form for given welding conditions.« less
Development Of Eej Model Based On Dense Ground-based Magnetometer Array
NASA Astrophysics Data System (ADS)
Matsushita, H.; Yoshikawa, A.; Uozumi, T.; Fujimoto, A.; Abe, S.; Ishitsuka I, J. K.; Veliz, O.; Rosales, D.; Safor, E.; Beteta, V.
2016-12-01
Equatorial Electro-jet(here after called EEJ) is the electric current which flows very narrow region in ionosphere of the earth, which is between +- 3 degree from dip latitude. The EEJ was noticed as the significant enhancement of daily variation of magnetic field, and later Hirono, (1950) explained it by adapting Cowling effect to the ionosphere of the earth. The EE index, is one of ICSWSE space weather indices, was developed by Uozumi et al., (2008). Then, ICSWSE has continued to monitor the EEJ activity by using this EE index. Fujimoto et al., (2016) investigated the relationship between solar activity and long term variation of EEJ, and Hamid et al., (2015) investigated longitudinal dependency of EEJ, both of them were based on EE index. The EE index provides EDst value, which is correspond to magnetic field change at dip equator caused by magnetospheric current such as ring current, and EUEL value, which is correspond to the one caused by ionospheric current such as EEJ and Sq. However, actual EEJ is not magnetic field but the current, and it has not only current intensity but also the width. Some previous paper reported the EEJ structure such as current density or the width of EEJ using satellite data (e.g. Lühr et al., 2004; Jadhav et al., 2002), which is good when it checks the longitudinal dependency because it shifts longitude in a day. However, the ground-based magnetometer may be well useful to investigate the day-to-day variability of EEJ because it is fixed to same location. So, we developed a model of EEJ, which can estimate the EEJ current structure by ground magnetometer using dense magnetometer array near dip equator. In this study, the EEJ structures along 75W and 135E longitude are represented, and are compared each other. The result shows that large standard deviation of both current density and the half width are identified, while previous studies reported constant half width (e.g. Lühr et al., 2004). When our EEJ model is compared with CM4 model, which was developed by Sabaka et al., (2004), large discrepancy between them was identified, so it should be more discussed the reason to produce more accurate EEJ model.
NASA Technical Reports Server (NTRS)
Khazanov, George V.
2006-01-01
The self-consistent treatment of the RC ion dynamics and EMIC waves, which are thought to exert important influences on the ion dynamical evolution, is an important missing element in our understanding of the storm-and recovery-time ring current evolution. Under certain conditions, relativistic electrons, with energies 21 MeV, can be removed from the outer radiation belt by EMIC wave scattering during a magnetic storm. That is why the modeling of EMIC waves is critical and timely issue in magnetospheric physics. To describe the RC evolution itself this study uses the ring current-atmosphere interaction model (RAM). RAM solves the gyration and bounce-averaged Boltzmann-Landau equation inside of geosynchronous orbit. Originally developed at the University of Michigan, there are now several branches of this model currently in use as describe by Liemohn namely those at NASA Goddard Space Flight Center This study will generalize the self-consistent theoretical description of RC ions and EMIC waves that has been developed by Khazanov and include the heavy ions and propagation effects of EMIC waves in the global dynamic of self-consistent RC - EMIC waves coupling. The results of our newly developed model that will be presented at GEM meeting, focusing mainly on the dynamic of EMIC waves and comparison of these results with the previous global RC modeling studies devoted to EMIC waves formation. We also discuss RC ion precipitations and wave induced thermal electron fluxes into the ionosphere.
Hybrid Structure Multichannel All-Fiber Current Sensor.
Jiang, Junzhen; Zhang, Hao; He, Youwu; Qiu, Yishen
2017-08-02
We have experimentally developed a hybrid-structure multi-channel all-fiber current sensor with ordinary silica fiber using fiber loop architecture. According to the rationale of time division multiplexing, the sensor combines parallel and serial structures. The purpose of the hybrid-structure multi-channel all-fiber current sensor is to get more information from the different measured points simultaneously. In addition, the hybrid-structure fiber current sensor exhibited a good linear response for each channel. A three-channel experiment was performed in the study and showed that the system could detect different current positions. Each channel could individually detect the current and needed a separate calibration system. Furthermore, the three channels will not affect each other.
A numerical study of the South China Sea Warm Current during winter monsoon relaxation
NASA Astrophysics Data System (ADS)
Zhang, Cong; Ding, Yang; Bao, Xianwen; Bi, Congcong; Li, Ruixiang; Zhang, Cunjie; Shen, Biao; Wan, Kai
2018-03-01
Using a Finite-Volume Community Ocean Model, we investigated the dynamic mechanism of the South China Sea Warm Current (SCSWC) in the northern South China Sea (NSCS) during winter monsoon relaxation. The model reproduces the mean surface circulation of the NSCS during winter, while model-simulated subtidal currents generally capture its current pattern. The model shows that the current over the continental shelf is generally southwestward, under a strong winter monsoon condition, but a northeastward counter-wind current usually develops between 50-and 100-m isobaths, when the monsoon relaxes. Model experiments, focusing on the wind relaxation process, show that sea level is elevated in the northwestern South China Sea (SCS), related to the persistent northeasterly monsoon. Following wind relaxation, a high sea level band builds up along the mid-shelf, and a northeastward current develops, having an obvious vertical barotropic structure. Momentum balance analysis indicates that an along-shelf pressure gradient provides the initial driving force for the SCSWC during the first few days following wind relaxation. The SCSWC subsequently reaches a steady quasi-geostrophic balance in the cross-shelf direction, mainly linked to sea level adjustment over the shelf. Lagrangian particle tracking experiments show that both the southwestward coastal current and slope current contribute to the northeastward movement of the SCSWC during winter monsoon relaxation.
Overview of NASA Studies on High-Temperature Ceramic Fibers
NASA Technical Reports Server (NTRS)
DiCarlo, James A.; Yun, Hee Mann
2001-01-01
NASA, DOD, and DOE are currently looking to the NASA UEET Program to develop ceramic matrix composites (CMC) for hot-section components in advanced power and propulsion systems - Success will depend strongly on developing ceramic fibers with a variety of key thermostructural properties, in particular, high as-produced tensile strength and retention of a large fraction of this strength for long times under the anticipated CMC service conditions. - Current UEET approach centers on selecting the optimum fiber type from commercially available fibers since the costs for development of advanced fibers are high and the markets for high-temperature CMC have yet to be established.
Conservation in Physics Teaching, History of Science and in Child Development
NASA Astrophysics Data System (ADS)
Speltini, Cristina; Dibar Ure, María Celia
The current work is an exploratory study on the ideas thatstudents in their fourth semester of engineering have about ``conservation''. Wereview the Piagetian position on the importance of conservations in logical operational structures inchild development and we comment upon other current trends in cognitive psychology. We discussbriefly the development of conservations in science during the 17th, 18th and 19th centuries and we pointout the contrast between this and how most textbooks introduce this subject. We have also carried out afirst, tentative analysis of the answers given by a sample of these students to a brief questionnaire about``conservation'' and ``non-conservation''.
NASA Astrophysics Data System (ADS)
Kyle-Henney, Stephen; Flitcroft, Stephen; Shatwell, Robert; Gibbon, David; Voss, Gary; Harkness, Patrick
2012-07-01
Silicon carbide fibre reinforced titanium composite material has been in development since the 1980s initially for high temperature structures on hypersonic vehicles (HOTOL, NASP). Since then development has focused on military and civil aircraft. Development in the European Union has reached a level of maturity where it is again being considered for space applications. Current activities include pressure vessels and studies for launch vehicles and satellite applications. The paper provides background to the technology key performance characteristics current application work and future activities. The renewed interest in hypersonic vehicles has also picked up on the potential for lightweight metallic composites.
Callaghan, Russell C.; Allebeck, Peter; Akre, Olof; McGlynn, Katherine A.; Sidorchuk, Anna
2018-01-01
Background Given current drug-policy reforms to decriminalize or legalize cannabis in numerous countries worldwide, it is critically important to understand the potential impacts of cannabis use on the development of cancer. The current study aims to assess the relation between cannabis use and the development of testicular cancer. Method The current study relied on a population-based sample (n = 49 343) of young men aged 18–21 years who underwent conscription assessment for Swedish military service in 1969–1970. The conscription process included a non-anonymous questionnaire eliciting information about drug use. Individual-level conscription information was linked to Swedish health and social registry data. Testicular cancers diagnosed between 1970 and 2011 were identified by ICD-7/8/9/10 testicular cancer codes in the Swedish National Patient Register, the Cancer Register, or the Cause of Death Register. Cox regression modeling was used to estimate the hazards associated with cannabis use and time to diagnosis of testicular cancer. Results No evidence was found of a significant relation between lifetime “ever” cannabis use and the subsequent development of testicular cancer [n = 45 250; 119 testicular cancer cases; adjusted hazard ratio (AHR) 1.42, 95% CI, 0.83, 2.45]. “Heavy” cannabis use (defined as usage of more than 50 times in lifetime, as measured at conscription) was associated with the incidence of testicular cancer (n = 45 250; 119 testicular cancer cases; AHR 2.57, 95% CI, 1.02, 6.50). Conclusion The current study provides additional evidence to the limited prior literature suggesting cannabis use may contribute to the development of testicular cancer. PMID:29093004
NASA Astrophysics Data System (ADS)
Kipervasser, M. V.; Gerasimuk, A. V.; Simakov, V. P.
2018-05-01
In the present paper a new registration method of such inadmissible phenomenon as cavitation in the operating mode of centrifugal pump is offered. Influence of cavitation and extent of its development on the value of mechanical power consumed by the pump from the electric motor is studied. On the basis of design formulas the joint mathematical model of centrifugal pumping unit with the synchronous motor is created. In the model the phenomena accompanying the work of a pumping installation in the cavitation mode are considered. Mathematical modeling of the pump operation in the considered emergency operation is carried out. The chart of stator current of the electric motor, depending on the degree of cavitation development of is received. On the basis of the analysis of the obtained data the conclusion on the possibility of registration of cavitation by the current of drive electric motor is made and the functional diagram of the developed protection system is offered, its operation principle is described.
Statewide Transportation Needs & Funding Study
DOT National Transportation Integrated Search
1995-05-01
The State Transportation Policy Initiative (STPI)is multi-phase study to examine : current transportation planning, growth management, and transportation funding : practices in Florida and to develop recommendations that can be the basis of : future ...
NASA Astrophysics Data System (ADS)
Patcharoen, Theerasak; Yoomak, Suntiti; Ngaopitakkul, Atthapol; Pothisarn, Chaichan
2018-04-01
This paper describes the combination of discrete wavelet transforms (DWT) and artificial intelligence (AI), which are efficient techniques to identify the type of inrush current, analyze the origin and possible cause on the capacitor bank switching. The experiment setup used to verify the proposed techniques can be detected and classified the transient inrush current from normal capacitor rated current. The discrete wavelet transforms are used to detect and classify the inrush current. Then, output from wavelet is acted as input of fuzzy inference system for discriminating the type of switching transient inrush current. The proposed technique shows enhanced performance with a discrimination accuracy of 90.57%. Both simulation study and experimental results are quite satisfactory with providing the high accuracy and reliability which can be developed and implemented into a numerical overcurrent (50/51) and unbalanced current (60C) protection relay for an application of shunt capacitor bank protection in the future.
ERIC Educational Resources Information Center
Milanowski, Anthony T.; Heneman, Herbert G., III; Kimball, Steven M.
2011-01-01
This paper reports on a study of the current state of the art in teaching assessment. The major goal of the study was to examine a sample of assessment systems and then develop a specification for a state-of the art performance assessment system to be used for human capital management functions. The authors hope was that this specification would…
Research of Steel-dielectric Transition Using Subminiature Eddy-current Transducer
NASA Astrophysics Data System (ADS)
Dmitriev, S. F.; Malikov, V. N.; Sagalakov, A. M.; Ishkov, A. V.
2018-05-01
The research aims to develop a subminiature transducer for electrical steel investigation. The authors determined the capability to study steel characteristics at different depths based on variations of eddy-current transducer amplitude at the steel-dielectric boundary. A subminiature transformer-type transducer was designed, which enables to perform local investigations of ferromagnetic materials using an eddy-current method based on local studies of the steel electrical conductivity. Having the designed transducer as a basis, a hardware-software complex was built to perform experimental studies of steel at the interface boundary. Test results are reported for a specimen with continuous and discrete measurements taken at different frequencies. The article provides the key technical information about the eddy current transformer used and describes the methodology of measurements that makes it possible to control steel to dielectric transition.
ERIC Educational Resources Information Center
Cotabish, Alicia; Dailey, Deborah; Hughes, Gail D.; Robinson, Ann
2011-01-01
In order to increase the quality and quantity of science instruction, elementary teachers must receive professional development in science learning processes. The current study was part of a larger randomized field study of teacher and student learning in science. In two districts in a southern state, researchers randomly assigned teacher…
ERIC Educational Resources Information Center
Amendum, Steven J.; Bratsch-Hines, Mary; Vernon-Feagans, Lynne
2018-01-01
The purpose of this study was to evaluate whether the Targeted Reading Intervention (TRI), a professional development and early reading intervention program delivered via webcam technology, could support the early reading progress of English learners (ELs). Participants for the current study were drawn from a larger three-year randomized…
ERIC Educational Resources Information Center
Tomeny, Theodore S.; Barry, Tammy D.; Bader, Stephanie H.
2012-01-01
Existing literature regarding the adjustment of siblings of children with an autism spectrum disorder (ASD) remains inconclusive, with some studies showing positive adjustment, others showing negative adjustment, and others showing no difference when compared to siblings of typically-developing children. For the current study, 42 parents of a…
Exploring Professional Identity Development in Alcohol and Drug Counselors in the 21st Century
ERIC Educational Resources Information Center
Simmons, Lori; Haas, Deborah; Massella, John; Young, Jared; Toth, Paul
2017-01-01
Professional identity development is an emerging area for alcohol and drug counselors. Few studies have investigated professional identity in alcohol and drug counselors (Ogborne, Braun, & Schmidt, 2001; Massella, Simons, Young, Haas, & Toth 2013). The goal of the current study is to add to this area of research. A total of 1,333 certified…
7th Grade Students' Mental Models about the Concept of "Sustainable Development"
ERIC Educational Resources Information Center
Keles, Özgül; Eris, Rabia; Aydogdu, Mustafa
2017-01-01
The purpose of the current study is to elicit the opinions constructed by 7th grade secondary school students about three components of the concept of sustainable development; environment, society and economy. Study group of the implementation consists of 20 students attending a public secondary school in 2014-2015 academic year. The study…
The Co-Development of Perceived Support and the Big Five in Middle and Older Adulthood
ERIC Educational Resources Information Center
Hill, Patrick L.; Weston, Sara J.; Jackson, Joshua J.
2018-01-01
The current study examined whether relationships also influence personality trait development during middle and older adulthood, focusing on the individual's perception of support from the relationship partner. Using data from the Health and Retirement Study (n = 20,422; mean age = 65.9 years), we examined the longitudinal relationships between…
Continuing Professional Development - Why Bother? Perceptions and Motivations of Teachers in Ireland
ERIC Educational Resources Information Center
McMillan, Dorothy J.; McConnell, Barbara; O'Sullivan, Helen
2016-01-01
In a larger study carried out by O'Sullivan "et al." to explore the perceptions and experiences of teachers in the Republic of Ireland and Northern Ireland who were engaged in continuing professional development (CPD), one of the significant findings to emerge was the key role of teacher motivation. The current study therefore focuses on…
ERIC Educational Resources Information Center
Harmon, Melinda R.
2013-01-01
This Grounded Theory study explored the identity development of four current and two former Reading Recovery students. The study focused on the interactions between self-efficacy, self-regulation and identity as students participated in the Reading Recovery intervention to capture change over time in the identity development of students who…
ERIC Educational Resources Information Center
Parlak, Özgür; Ziegler, Nicole
2017-01-01
Although previous research has demonstrated the efficacy of recasts on second language (L2) morphology and lexis (e.g., Li, 2010; Mackey & Goo, 2007), few studies have examined their effect on learners' phonological development (although see Saito, 2015; Saito & Lyster, 2012). The current study investigates the impact of recasts on the…
ERIC Educational Resources Information Center
Bilodeau, Brent
2005-01-01
Few non-pathologizing models of transgender identity development currently exist. This study uses an adaptation of the D'Augelli (1994) lifespan model of sexual orientation identity development to consider the lives of transgender college students. Interviews with two transgender-identified students find that they have developmental experiences in…
Development of Neural Systems for Processing Social Exclusion from Childhood to Adolescence
ERIC Educational Resources Information Center
Bolling, Danielle Z.; Pitskel, Naomi B.; Deen, Ben; Crowley, Michael J.; Mayes, Linda C.; Pelphrey, Kevin A.
2011-01-01
Adolescence is a period of development in which peer relationships become especially important. A computer-based game (Cyberball) has been used to explore the effects of social exclusion in adolescents and adults. The current functional magnetic resonance imaging (fMRI) study used Cyberball to extend prior work to the cross-sectional study of…
Single Particle Orientation and Rotational Tracking (SPORT) in biophysical studies
DOE Office of Scientific and Technical Information (OSTI.GOV)
Gu, Yan; Ha, Ji Won; Augspurger, Ashley E.
The single particle orientation and rotational tracking (SPORT) techniques have seen rapid development in the past 5 years. Recent technical advances have greatly expanded the applicability of SPORT in biophysical studies. In this feature article, we survey the current development of SPORT and discuss its potential applications in biophysics, including cellular membrane processes and intracellular transport.
The Development of a Mathematics Self-Report Inventory for Turkish Elementary Students
ERIC Educational Resources Information Center
Akin, Ayça; Güzeller, Cem Oktay; Evcan, Sinem Sezer
2016-01-01
The purpose of the current study is to develop a mathematics self-report inventory (MSRI) to measure Turkish elementary students' mathematics expectancy beliefs and task values based on the expectancy-value theory of achievement motivation. In Study-1 (n = 1,315), exploratory factor analysis (EFA) and reliability analysis are used to evaluate the…
ERIC Educational Resources Information Center
Gonzalez, Marggie Denise
2016-01-01
This multiple case study examines four groups of secondary mathematics teachers engaged in a Lesson Study approach to professional development where they planned and taught lessons that integrate technology. Informed by current literature, a framework was developed to focus on the dimensions of teacher's knowledge to teach mathematics with…
ERIC Educational Resources Information Center
Gold, Bernadette; Holodynski, Manfred
2015-01-01
The current study describes the development and construct validation of a situational judgment test for assessing the strategic knowledge of classroom management in elementary schools. Classroom scenarios and accompanying courses of action were constructed, of which 17 experts confirmed the content validity. A pilot study and a cross-validation…
PESTE Factors in Developing a Framework for E-Learning
ERIC Educational Resources Information Center
Graham, Deryn
2007-01-01
This article describes the development of a framework for e-learning and presents the findings of a study investigating whether the use of blended learning can fulfil or at least accommodate some of the human requirements presently neglected by current e-learning systems. The study evaluated the in-house system, Teachmat, and discussed how the use…
ERIC Educational Resources Information Center
Beachy, Rachel Rayburn
2017-01-01
This dissertation is developed around two studies created with the goal of describing and quantifying current educators' knowledge and perceptions of reading assessment and subsequent data-based instructional decision making. Unique to the field, a critical component of this study is an emphasis on educators' development of "data…
ERIC Educational Resources Information Center
Childress, Amy
2011-01-01
While several models of adult writing have been proposed and studied, the development of writing skills in young children has only recently garnered attention. Using measures of fine-motor, language, working memory, and attention/executive functions, the current study explored motor and cognitive skills that may contribute to writing skill in…
A Confirmatory Factor Analysis of Reilly's Role Overload Scale
ERIC Educational Resources Information Center
Thiagarajan, Palaniappan; Chakrabarty, Subhra; Taylor, Ronald D.
2006-01-01
In 1982, Reilly developed a 13-item scale to measure role overload. This scale has been widely used, but most studies did not assess the unidimensionality of the scale. Given the significance of unidimensionality in scale development, the current study reports a confirmatory factor analysis of the 13-item scale in two samples. Based on the…
Reading Development and Achievement of 4th-Grade Hmong Students
ERIC Educational Resources Information Center
Mahowald, Megan; Loughnane, Megan
2016-01-01
Researchers and practitioners alike have noted that Hmong students in the United States do not achieve as well as their monolingual peers and other bilingual students. The current mixed-methods study is designed to describe reading development and achievement of 4th-grade Hmong students in one large, urban school district. This study explores the…
The Long Arm of Childhood: Preschool Associations with Adolescent Health
ERIC Educational Resources Information Center
Sabol, Terri J.; Hoyt, Lindsay Till
2017-01-01
The current study examines the extent to which participation in preschool at age 4 is associated with blood pressure, body mass index, and awakening cortisol at age 15. We capitalize on data from the National Institute of Child Health and Human Development Study of Early Child Care and Youth Development to examine differences in adolescent health…
ERIC Educational Resources Information Center
Borsuk, Ellen R.
2010-01-01
Research and development of measures to document ongoing learning within the content areas are in the beginning stages. As such, the current study adds to efforts in the development of the vocabulary-matching measure. Using a modified format of the previously studied vocabulary-matching measure, 63 middle school students completed alternate forms…
ERIC Educational Resources Information Center
Vuontela, Virve; Jiang, Ping; Tokariev, Maksym; Savolainen, Petri; Ma, YuanYe; Aronen, Eeva T.; Fontell, Tuija; Liiri, Tiina; Ahlstrom, Matti; Salonen, Oili; Carlson, Synnove
2013-01-01
Developmental studies have demonstrated that cognitive processes such as attention, suppression of interference and memory develop throughout childhood and adolescence. However, little is currently known about the development of top-down control mechanisms and their influence on cognitive performance. In the present study, we used functional…
ERIC Educational Resources Information Center
Putkinen, Vesa; Tervaniemi, Mari; Saarikivi, Katri; Ojala, Pauliina; Huotilainen, Minna
2014-01-01
Adult musicians show superior auditory discrimination skills when compared to non-musicians. The enhanced auditory skills of musicians are reflected in the augmented amplitudes of their auditory event-related potential (ERP) responses. In the current study, we investigated longitudinally the development of auditory discrimination skills in…
Developing Software for Pharmacodynamics and Bioassay Studies
The objective of the project is to develop a software system to process general pharmacologic, toxicological, or other biomedical research data that...exhibit a non-monotonic dose-response relationship - for which the current parametric models fail. The software will analyze dose-response
Development of data measurement techniques for traffic operations analysis at intersections
DOT National Transportation Integrated Search
1985-06-01
This study was undertaken for the purpose of developing intersection data collection methods and approaches which reflect the current needs of engineers and the state-of-the-art capabilities of available equipment. A literature review summarizes perv...
Photo-electronic current transport in back-gated graphene transistor
NASA Astrophysics Data System (ADS)
Srivastava, Ashok; Chen, Xinlu; Pradhan, Aswini K.
2017-04-01
In this work, we have studied photo-electronic current transport in a back-gated graphene field-effect transistor. Under the light illumination, band bending at the metal/graphene interface develops a built-in potential which generates photonic current at varying back-gate biases. A typical MOSFET type back-gated transistor structure uses a monolayer graphene as the channel layer formed over the silicon dioxide/silicon substrate. It is shown that the photo-electronic current consists of current contributions from photovoltaic, photo-thermoelectric and photo-bolometric effects. A maximum external responsivity close to 0.0009A/W is achieved at 30μW laser power source and 633nm wavelength.
NASA Astrophysics Data System (ADS)
Chernyak, Vladimir Y.; Klein, John R.; Sinitsyn, Nikolai A.
2012-04-01
This article studies Markovian stochastic motion of a particle on a graph with finite number of nodes and periodically time-dependent transition rates that satisfy the detailed balance condition at any time. We show that under general conditions, the currents in the system on average become quantized or fractionally quantized for adiabatic driving at sufficiently low temperature. We develop the quantitative theory of this quantization and interpret it in terms of topological invariants. By implementing the celebrated Kirchhoff theorem we derive a general and explicit formula for the average generated current that plays a role of an efficient tool for treating the current quantization effects.
NASA Astrophysics Data System (ADS)
Xiong, Jia-ming; Li, Lee; Dai, Hong-yu; Wu, Hai-bo; Peng, Ming-yang; Lin, Fu-chang
2018-03-01
During the formation of a high current impulse discharge arc, objects near the discharge arc will be strongly impacted. In this paper, a high power, high current gas switch is used as the site of the impulse discharge arc. The explosion wave theory and the arc channel energy balance equation are introduced to analyze the development of the shock wave overpressure driven by the high current impulse discharge arc, and the demarcation point of the arc channel is given, from which the energy of the arc channel is no longer converted into shock waves. Through the analysis and calculation, it is found that the magnitude of the shock wave overpressure caused by impulse discharge arc expansion is closely related to the arc current rising rate. The arc shock wave overpressure will undergo a slow decay process and then decay rapidly. The study of this paper will perform the function of deepening the understanding of the physical nature of the impulse arc discharge, which can be used to explain the damage effect of the high current impulse discharge arc.
Avoidant Personality Disorder: a Current Review.
Weinbrecht, Anna; Schulze, Lars; Boettcher, Johanna; Renneberg, Babette
2016-03-01
This review focuses on recent research on diagnostic aspects, etiology, and treatment of avoidant personality disorder (AVPD). Current studies stress the close relation between AVPD and social anxiety disorder, the influence of genetic factors in the development of AVPD, and the relative stability of symptoms. Treatment approaches should target the pervasive patterns of social inhibition, feelings of inadequacy, and hypersensitivity to negative evaluation. Empirical evidence for cognitive-behavior and schema therapy is promising. Few other therapeutic approaches have been developed, but until now, these have only been investigated in case studies. We conclude that AVPD qualifies as a neglected disorder and that more research specifically on avoidant personality disorder symptoms and its treatment is needed.
Control approach development for variable recruitment artificial muscles
NASA Astrophysics Data System (ADS)
Jenkins, Tyler E.; Chapman, Edward M.; Bryant, Matthew
2016-04-01
This study characterizes hybrid control approaches for the variable recruitment of fluidic artificial muscles with double acting (antagonistic) actuation. Fluidic artificial muscle actuators have been explored by researchers due to their natural compliance, high force-to-weight ratio, and low cost of fabrication. Previous studies have attempted to improve system efficiency of the actuators through variable recruitment, i.e. using discrete changes in the number of active actuators. While current variable recruitment research utilizes manual valve switching, this paper details the current development of an online variable recruitment control scheme. By continuously controlling applied pressure and discretely controlling the number of active actuators, operation in the lowest possible recruitment state is ensured and working fluid consumption is minimized. Results provide insight into switching control scheme effects on working fluids, fabrication material choices, actuator modeling, and controller development decisions.
ERIC Educational Resources Information Center
Tell, Bjorn V.
In response to technological developments that are bringing about changes in the information field, this paper focuses on factors that should be considered in planning for curriculum changes in library education in the developing nations. The paper comprises information on: (1) the background of the study; (2) the importance of scientific journal…
Liquefaction Resistance Based on Shear Wave Velocity
DOT National Transportation Integrated Search
1999-01-01
This report reviews the current simplified procedures for evaluating the liquefaction resistance of granular soil deposits using small-strain shear wave velocity. These procedures were developed from analytical studies, laboratory studies, or very li...
NASA Technical Reports Server (NTRS)
Buzulukova, N.; Fok, M.-C.; Goldstein, J.; Valek, P.; McComas, D. J.; Brandt, P. C.
2010-01-01
We present a comparative study of ring current dynamics during strong and moderate storms. The ring current during the strong storm is studied with IMAGE/HENA data near the solar cycle maximum in 2000. The ring current during the moderate storm is studied using energetic neutral atom (ENA) data from the Two Wide-Angle Imaging Neutral- Atom Spectrometers (TWINS) mission during the solar minimum in 2008. For both storms, the local time distributions of ENA emissions show signatures of postmidnight enhancement (PME) during the main phases. To model the ring current and ENA emissions, we use the Comprehensive Ring Current Model (CRCM). CRCM results show that the main-phase ring current pressure peaks in the premidnight-dusk sector, while the most intense CRCM-simulated ENA emissions show PME signatures. We analyze two factors to explain this difference: the dependence of charge-exchange cross section on energy and pitch angle distributions of ring current. We find that the IMF By effect (twisting of the convection pattern due to By) is not needed to form the PME. Additionally, the PME is more pronounced for the strong storm, although relative shielding and hence electric field skewing is well developed for both events.
NASA Astrophysics Data System (ADS)
Radevici, Ivan; Tiira, Jonna; Sadi, Toufik; Oksanen, Jani
2018-05-01
Current crowding close to electrical contacts is a common challenge in all optoelectronic devices containing thin current spreading layers (CSLs). We analyze the effects of current spreading on the operation of the so-called double diode structure (DDS), consisting of a light emitting diode (LED) and a photodiode (PD) fabricated within the same epitaxial growth process, and providing an attractive platform for studying electroluminescent (EL) cooling under high bias conditions. We show that current spreading in the common n-type layer between the LED and the PD can be dramatically improved by the strong optical coupling between the diodes, as the coupling enables a photo-generated current through the PD. This reduces the current in the DDS CSL and enables the study of EL cooling using structures that are not limited by the conventional light extraction challenges encountered in normal LEDs. The current spreading in the structures is studied using optical imaging techniques, electrical measurements, simulations, as well as simple equivalent circuit models developed for this purpose. The improved current spreading leads further to a mutual dependence with the coupling efficiency, which is expected to facilitate the process of optimizing the DDS. We also report a new improved value of 63% for the DDS coupling quantum efficiency.
NASA Astrophysics Data System (ADS)
Boyer, Mark; Andre, Robert; Gates, David; Gerhardt, Stefan; Menard, Jonathan; Poli, Francesca
2015-11-01
One of the major goals of NSTX-U is to demonstrate non-inductive operation. To facilitate this and other program goals, the center stack has been upgraded and a second neutral beam line has been added with three sources aimed more tangentially to provide higher current drive efficiency and the ability to shape the current drive profile. While non-inductive start-up and ramp-up scenarios are being developed, initial non-inductive studies will likely rely on clamping the Ohmic coil current after the plasma current has been established inductively. In this work the ability to maintain control of stored energy and plasma current once the Ohmic coil has been clamped is explored. The six neutral beam sources and the mid-plane outer gap of the plasma are considered as actuators. System identification is done using TRANSP simulations in which the actuators are modulated around a reference shot. The resulting reduced model is used to design an optimal control law with anti-windup and a recently developed framework for closed loop simulations in TRANSP is used to test the control. Limitations due to actuator saturation are assessed and robustness to beam modulation, changes in the plasma density and confinement, and changes in density and temperature profile shapes are studied. Supported by US DOE contract DE-AC02-09CH11466.
NASA Astrophysics Data System (ADS)
Uhlenbrock, K.; Landau, E. A.; Hankin, E. R.
2013-12-01
Federally funded scientific research is one of the building blocks of technological advancement and economic growth. This research can also lead to transformational ideas and discoveries. In our current fiscal environment, strategies to rein in federal spending have become a priority, although they have proven to be complex. The possible deals and negotiations to reduce federal spending may hinder the work of the scientific community to serve society. Since 2005 federal investment in research and development has slowed. The average annual growth in federal funding for scientific research from 2004 - 2009 was 0.9% as compared to 3.3% over the previous 20 years. What does the current budget situation mean for science? It means reductions in basic and applied research, interruptions in long-term monitoring and data collection, an inability to repair or build infrastructure, and less federal grant support for current and future scientists. I will first provide an update on the current federal budget situation and examples of how current policies are impacting the scientific community. Second, I will present a case study of the effect of reduced federal investment in science. Specifically, I will discuss how investments in research and development have far-reaching impacts on society and examine how reduced funding impairs valuable research efforts.
State of Idaho Port of Entry Study
DOT National Transportation Integrated Search
2016-05-01
The purpose of this study was to evaluate Idaho's Ports of Entry (POE) Program to identify its strengths and weaknesses, and provide recommendations for future program development and operations. As part of the study, current Idaho POE business proce...
Analysis of the U.S. geological survey streamgaging network
Scott, A.G.
1987-01-01
This paper summarizes the results from the first 3 years of a 5-year cost-effectiveness study of the U.S. Geological Survey streamgaging network. The objective of the study is to define and document the most cost-effective means of furnishing streamflow information. In the first step of this study, data uses were identified for 3,493 continuous-record stations currently being operated in 32 States. In the second step, evaluation of alternative methods of providing streamflow information, flow-routing models, and regression models were developed for estimating daily flows at 251 stations of the 3,493 stations analyzed. In the third step of the analysis, relationships were developed between the accuracy of the streamflow records and the operating budget. The weighted standard error for all stations, with current operating procedures, was 19.9 percent. By altering field activities, as determined by the analyses, this could be reduced to 17.8 percent. The existing streamgaging networks in four Districts were further analyzed to determine the impacts that satellite telemetry would have on the cost effectiveness. Satellite telemetry was not found to be cost effective on the basis of hydrologic data collection alone, given present cost of equipment and operation.This paper summarizes the results from the first 3 years of a 5-year cost-effectiveness study of the U. S. Geological Survey streamgaging network. The objective of the study is to define and document the most cost-effective means of furnishing streamflow information. In the first step of this study, data uses were identified for 3,493 continuous-record stations currently being operated in 32 States. In the second step, evaluation of alternative methods of providing streamflow information, flow-routing models, and regression models were developed for estimating daily flows at 251 stations of the 3, 493 stations analyzed. In the third step of the analysis, relationships were developed between the accuracy of the streamflow records and the operating budget. The weighted standard error for all stations, with current operating procedures, was 19. 9 percent. By altering field activities, as determined by the analyses, this could be reduced to 17. 8 percent. Additional study results are discussed.
The current state of cancer family history collection tools in primary care: a systematic review.
Qureshi, Nadeem; Carroll, June C; Wilson, Brenda; Santaguida, Pasqualina; Allanson, Judith; Brouwers, Melissa; Raina, Parminder
2009-07-01
Systematic collection of family history is a prerequisite for identifying genetic risk. This study reviewed tools applicable to the primary care assessment of family history of breast, colorectal, ovarian, and prostate cancer. MEDLINE, EMBASE, CINAHL, and Cochrane Central were searched for publications. All primary study designs were included. Characteristics of the studies, the family history collection tools, and the setting were evaluated. Of 40 eligible studies, 18 relevant family history tools were identified, with 11 developed for use in primary care. Most collected information on more than one cancer and on affected relatives used self-administered questionnaires and paper-based formats. Eleven tools had been evaluated relative to current practice, demonstrating 46-78% improvement in data recording over family history recording in patient charts and 75-100% agreement with structured genetic interviews. Few tools have been developed specifically for primary care settings. The few that have been evaluated performed well. The very limited evidence, which depends in part on extrapolation from studies in settings other than primary care, suggests that systematic tools may add significant family health information compared with current primary care practice. The effect of their use on health outcomes has not been evaluated.
Zika Virus: Recent Advances towards the Development of Vaccines and Therapeutics
McArthur, Monica A.
2017-01-01
Zika is a rapidly emerging public health threat. Although clinical infection is frequently mild, significant neurological manifestations have been demonstrated in infants born to Zika virus (ZIKV) infected mothers. Due to the substantial ramifications of intrauterine infection, effective counter-measures are urgently needed. In order to develop effective anti-ZIKV vaccines and therapeutics, improved animal models and a better understanding of immunological correlates of protection against ZIKV are required. This review will summarize what is currently known about ZIKV, the clinical manifestations and epidemiology of Zika as well as, the development of animal models to study ZIKV infection, host immune responses against ZIKV, and the current state of development of vaccines and therapeutics against ZIKV. PMID:28608813
Designing and Developing Mobile Based Instruction: A Designer's Perspective
ERIC Educational Resources Information Center
Pastore, Raymond S.; Martin, Florence
2013-01-01
Mobile devices are increasingly being used in classrooms and corporations as a means to deliver instructional content. Currently, there is limited research on how to best design and develop mobile based instruction. As a result, the purpose of this research study was to examine students' perceptions of designing and developing mobile-based…
Communicative Acts of a Child with Rubinstein-Taybi Syndrome during Early Communicative Development
ERIC Educational Resources Information Center
Carvey, Jayme S.; Bernhardt, B. May
2009-01-01
Rubinstein-Taybi syndrome (RTS) is a rare genetic developmental disorder that often shows associated language delay. However, literature on language development in RTS is very limited, particularly for the period of early communicative development, when standardized testing can be minimally informative. The purpose of the current study was to…
Theory and Practice of Community Development: A Case Study from the United Kingdom.
ERIC Educational Resources Information Center
Popple, Keith; Quinney, Anne
2002-01-01
A top-down approach to British community development is rooted in Victorian paternalism, a bottom-up approach in radical action. The case of ACHIEVE (Academic Centre for Health Improvement and Evidence of Effectiveness) shows how the current government's top-down approach is inadequate and potentially exploitive. It emphasizes development and…
A Proposed Educational Program for Agricultural Development in Iraq.
ERIC Educational Resources Information Center
Alsamarrae, Hatam Ali
The general purpose of this study was to develop an educational program for agricultural development in Iraq, and to identify the best method for its implementation. The proposed program was based primarily upon relevant factors identified through data collection from the following sources: official records, current literature, and the writer's…
ERIC Educational Resources Information Center
Spencer, Natalie F.; Dowden, Angel Riddick
2014-01-01
Gifted African American students are underrepresented and underserved in gifted education. The current article provides an overview of proper identification, racial identity development implications, psycho-social concerns and the importance of family involvement in the development of gifted African American students. A case study is presented to…
USDA-ARS?s Scientific Manuscript database
Fertilization and development of the preimplantation embryo is under genetic control. The goal of the current study was to test 434 single nucleotide polymorphisms (SNPs) for association with genetic variation in fertilization and early embryonic development. The approach was to produce embryos from...
Classification of Staff Development Programmes and Effects Perceived by Teachers
ERIC Educational Resources Information Center
De Rijdt, Catherine; Dochy, Filip; Bamelis, Sofie; van der Vleuten, Cees
2016-01-01
Educational institutions offer diverse staff development programmes to allow staff members to keep up with educational innovations and to guarantee educational quality. The current study investigates by means of a survey and semi-structured interviews whether the teacher perceives staff development as a management model, a shop-floor model or a…
ERIC Educational Resources Information Center
Zhumasheva, Anara; Zhumabaeva, Zaida; Sakenov, Janat; Vedilina, Yelena; Zhaxylykova, Nuriya; Sekenova, Balkumis
2016-01-01
The current study focuses on the research topic of creating a theoretical model of development of information competence among students enrolled in elective courses. In order to examine specific features of the theoretical model of development of information competence among students enrolled in elective courses, we performed an analysis of…
Professional Development in the Digital Age: Case Studies of Blended Communities of Practice
ERIC Educational Resources Information Center
Wagner, Jennifer Michelle
2010-01-01
The need for sustainable, meaningful teacher professional development to support the rising professional demands remains an on-going challenge for education. The use of current technologies, such as online learning systems, to leverage the development of learning communities, including communities of practice (CoPs), where teachers with a common…
Development of Universal Values in School Management Scale (UVISMS)
ERIC Educational Resources Information Center
Sagir, Mahmut
2014-01-01
Current study aims to develop a scale to identify the universal values of school administrators in school management. In order to develop the scale, academic resources were reviewed and a 40-item draft data collection instrument was created by taking the views and suggestions of 5 school administrators, 5 academicians and 5 education inspectors…
Using Classroom Artifacts to Measure the Efficacy of a Professional Development. CRESST Report 761
ERIC Educational Resources Information Center
Silk, Yael; Silver, David; Amerian, Stephanie; Nishimura, Claire; Boscardin, Christy Kim
2009-01-01
This report describes a classroom artifact measure and presents early findings from an efficacy study of WestEd's Reading Apprenticeship (RA) professional development program. The professional development is designed to teach high school teachers how to integrate subject-specific literacy instruction into their regular curricula. The current RA…
Development of Educational Management System in Small Primary School
ERIC Educational Resources Information Center
Alsammarry, Yupayao; Sirisuthi, Chaiyuth; Duangcharthom, Surat
2016-01-01
The purposes of the research were: (1) to study the factors of Educational Management System in Small Primary School; (2) to investigate current situations problems and guidelines of developing educational management in small primary school; (3) to develop Educational Management System in Small Primary School; and (4) to examine the results of…
Interventions addressing general parenting to prevent or treat childhood obesity.
Gerards, Sanne M P L; Sleddens, Ester F C; Dagnelie, Pieter C; de Vries, Nanne K; Kremers, Stef P J
2011-06-01
Observational studies increasingly emphasize the impact of general parenting on the development of childhood overweight and obesity. The aim of the current literature review was to provide an overview of interventions addressing general parenting in order to prevent or treat childhood obesity. Electronic literature databases were systematically searched for relevant studies. Seven studies were eligible for inclusion. The studies described four different general parenting programs, which were supplemented with lifestyle components (i.e., physical activity and nutrition). All studies showed significant small to moderate intervention effects on at least one weight-related outcome measure. The current review shows that despite the emerging observational evidence for the role of parenting in children's weight-related outcomes, few interventions have been developed that address general parenting in the prevention of childhood obesity. These interventions provide evidence that the promotion of authoritative parenting is an effective strategy for the prevention and management of childhood obesity.
Studies on the current state of water quality in the Segamat River
NASA Astrophysics Data System (ADS)
Razelan, Faridah Mohd; Tahir, Wardah; E. M Yahaya, Nasehir Khan
2018-04-01
Nowadays, pollution has become a major concern in developed and developing countries. In a study on the current state of Segamat River water quality; on-site data collection and observation and also laboratory data analysis have been implemented. Studies showed that the downstream of the Segamat River has recorded a significant reduction in quality of water during the dry season compared to the wet season. The deterioration of water quality is caused by the activities along the river such as palm oil plantation, municipal waste and waste from settlements. It was also recorded that the point sources were dominating the pollution at Segamat River during the dry season. However, during the wet season, the water quality was impaired by the non-point sources which originated from the upstream of the river.
Potential developmental neurotoxicity of pesticides used in Europe
Bjørling-Poulsen, Marina; Andersen, Helle Raun; Grandjean, Philippe
2008-01-01
Pesticides used in agriculture are designed to protect crops against unwanted species, such as weeds, insects, and fungus. Many compounds target the nervous system of insect pests. Because of the similarity in brain biochemistry, such pesticides may also be neurotoxic to humans. Concerns have been raised that the developing brain may be particularly vulnerable to adverse effects of neurotoxic pesticides. Current requirements for safety testing do not include developmental neurotoxicity. We therefore undertook a systematic evaluation of published evidence on neurotoxicity of pesticides in current use, with specific emphasis on risks during early development. Epidemiologic studies show associations with neurodevelopmental deficits, but mainly deal with mixed exposures to pesticides. Laboratory experimental studies using model compounds suggest that many pesticides currently used in Europe – including organophosphates, carbamates, pyrethroids, ethylenebisdithiocarbamates, and chlorophenoxy herbicides – can cause neurodevelopmental toxicity. Adverse effects on brain development can be severe and irreversible. Prevention should therefore be a public health priority. The occurrence of residues in food and other types of human exposures should be prevented with regard to the pesticide groups that are known to be neurotoxic. For other substances, given their widespread use and the unique vulnerability of the developing brain, the general lack of data on developmental neurotoxicity calls for investment in targeted research. While awaiting more definite evidence, existing uncertainties should be considered in light of the need for precautionary action to protect brain development. PMID:18945337
Comparison of thruster configurations in attitude control systems. M.S. Thesis. Progress Report
NASA Technical Reports Server (NTRS)
Boland, J. S., III; Drinkard, D. M., Jr.; White, L. R.; Chakravarthi, K. R.
1973-01-01
Several aspects concerning reaction control jet systems as used to govern the attitude of a spacecraft were considered. A thruster configuration currently in use was compared to several new configurations developed in this study. The method of determining the error signals which control the firing of the thrusters was also investigated. The current error determination procedure is explained and a new method is presented. Both of these procedures are applied to each of the thruster configurations which are developed and comparisons of the two methods are made.
NASA Technical Reports Server (NTRS)
Flynn, Michael
2004-01-01
Design for microgravity has traditionally not been well integrated early on into the development of advanced life support (ALS) technologies. NASA currently has a many ALS technologies that are currently being developed to high technology readiness levels but have not been formally evaluated for microgravity compatibility. Two examples of such technologies are the Vapor Phase Catalytic Ammonia Removal Technology and the Direct Osmotic Concentration Technology. This presentation will cover the design of theses two systems and will identify potential microgravity issues.
Feasibility of Producing and Using Biomass-Based Diesel and Jet Fuel in the United States
DOE Office of Scientific and Technical Information (OSTI.GOV)
Milbrandt, A.; Kinchin, C.; McCormick, R.
The study summarizes the best available public data on the production, capacity, cost, market demand, and feedstock availability for the production of biomass-based diesel and jet fuel. It includes an overview of the current conversion processes and current state-of-development for the production of biomass-based jet and diesel fuel, as well as the key companies pursuing this effort. Thediscussion analyzes all this information in the context of meeting the RFS mandate, highlights uncertainties for the future industry development, and key business opportunities.
Educational Planning for the Future Development of Pasco-Hernando Community College.
ERIC Educational Resources Information Center
McGuffey, C. W.; And Others
The purpose of this study was to develop a long-range educational plan for the future development and expansion of the current program and facilities of Pasco-Hernando Community College. An analysis has been made of available data and related information as a basis for the preparation of a generalized plan to guide the future development of the…
Rey-Ladino, Jose; Ross, Allen GP; Cripps, Allan W
2014-01-01
This review examines the immunity, immunopathology, and contemporary problems of vaccine development against sexually transmitted Chlamydia trachomatis. Despite improved surveillance and treatment initiatives, the incidence of C. trachomatis infection has increased dramatically over the past 30 years in both the developed and developing world. Studies in animal models have shown that protective immunity to C. trachomatis is largely mediated by Th1 T cells producing IFN-γ which is needed to prevent dissemination of infection. Similar protection appears to develop in humans but in contrast to mice, immunity in humans may take years to develop. Animal studies and evidence from human infection indicate that immunity to C. trachomatis is accompanied by significant pathology in the upper genital tract. Although no credible evidence is currently available to indicate that autoimmunity plays a role, nevertheless, this underscores the necessity to design vaccines strictly based on chlamydial-specific antigens and to avoid those displaying even minimal sequence homologies with host molecules. Current advances in C. trachomatis vaccine development as well as alternatives for designing new vaccines for this disease are discussed. A novel approach for chlamydia vaccine development, based on targeting endogenous dendritic cells, is described. PMID:25483666
Mueller, Julia S.; Cheek, Brandon D.; Chen, Qingman; Groeschel, Jillian R.; Brewer, Shannon K.; Grabowski, Timothy B.
2013-01-01
Pelagic broadcast spawning cyprinids are common to Great Plains rivers and streams. This reproductive guild produces non-adhesive semi-buoyant eggs that require sufficient current velocity to remain in suspension during development. Although studies have shown that there may be a minimum velocity needed to keep the eggs in suspension, this velocity has not been estimated directly nor has the influence of physicochemical factors on egg buoyancy been determined. We developed a simple, inexpensive flow chamber that allowed for evaluation of minimum current velocity needed to keep semi-buoyant eggs in suspension at any time frame during egg development. The device described here has the capability of testing the minimum current velocity needed to keep semi-buoyant eggs in suspension at a wide range of physicochemical conditions. We used gellan beads soaked in freshwater for 0, 24, and 48 hrs as egg surrogates and evaluated minimum current velocities necessary to keep them in suspension at different combinations of temperature (20.0 ± 1.0° C, 25.0 ± 1.0° C, and 28.0 ± 1.0° C) and total dissolved solids (TDS; 1,000 mg L-1, 3,000 mg L-1, and 6,000 mg L-1). We found that our methodology generated consistent, repeatable results within treatment groups. Current velocities ranging from 0.001–0.026 needed to keep the gellan beads in suspension were negatively correlated to soak times and TDS and positively correlated with temperature. The flow chamber is a viable approach for evaluating minimum current velocities needed to keep the eggs of pelagic broadcast spawning cyprinids in suspension during development.
ERIC Educational Resources Information Center
Khotbancha, Wijitra; Chantarasombat, Chalard; Sriampai, Anan
2015-01-01
The objectives of this research were: 1) to study the current situation and problem of Knowledge Management of the office of the primary education service area, 2) to develop a Knowledge Management model, 3) to study the success of the implementation of the Knowledge Management system. There were 25 persons in the target group. There were 2 kinds…
[Chronic lymphocytic leukaemia: current management].
Aurran-Schleinitz, T; Arnoulet, C; Ivanov, V; Coso, D; Rey, J; Schiano, J-M; Stoppa, A-M; Bouabdallah, R; Gastaut, J-A
2008-05-01
Chronic lymphocytic leukemia (CLL) is the most common leukaemia in the Western world. Recent advancement in the aetiology, pathophysiology and the development of new therapeutics tools have significantly modified the current management of CLL. The cellular origin of CLL is still unknown. The current main hypothesis will be first briefly described. This review will then focus on the newly defined prognostic factors and the development and use of new drugs for the treatment of CLL. To describe the modern and practical management of CLL, we will compare classical and new prognostic markers. Then, we will discuss the various therapeutic options including chemotherapy and immunotherapy (monoclonal antibodies, allogenic transplantation), and define their current respective indications. These new diagnostic and prognostic markers will allow the characterization of new prognostic subgroups of patients. This will lead to a targeted and individualized therapeutic approach. We will present the first results of clinical trials and the on-going studies conducted in this disease.
Limiting current of intense electron beams in a decelerating gap
NASA Astrophysics Data System (ADS)
Nusinovich, G. S.; Beaudoin, B. L.; Thompson, C.; Karakkad, J. A.; Antonsen, T. M.
2016-02-01
For numerous applications, it is desirable to develop electron beam driven efficient sources of electromagnetic radiation that are capable of producing the required power at beam voltages as low as possible. This trend is limited by space charge effects that cause the reduction of electron kinetic energy and can lead to electron reflection. So far, this effect was analyzed for intense beams propagating in uniform metallic pipes. In the present study, the limiting currents of intense electron beams are analyzed for the case of beam propagation in the tubes with gaps. A general treatment is illustrated by an example evaluating the limiting current in a high-power, tunable 1-10 MHz inductive output tube (IOT), which is currently under development for ionospheric modification. Results of the analytical theory are compared to results of numerical simulations. The results obtained allow one to estimate the interaction efficiency of IOTs.
The atmospheric effects of stratospheric aircraft: A topical review
NASA Technical Reports Server (NTRS)
Johnston, Harold S.; Prather, M. J.; Watson, R. T.
1991-01-01
In the late 1960s the aircraft industry became interested in developing a fleet of supersonic transports (SSTs). Between 1972 and 1975, the Climatic Impact Assessment Program (CIAP) studied the possible environmental impact of SSTs. For environmental and economic reasons, the fleet of SSTs was not developed. The Upper Atmosphere Research Program (UARP) has recently undertaken the responsibility of directing scientific research needed to assess the atmospheric impact of supersonic transports. The UARP and the High-Speed Research Program asked Harold Johnston to review the current understanding of aircraft emissions and their effect on the stratosphere. Johnston and his colleagues have recently re-examined the SST problem using current models for stratospheric ozone chemistry. A unique view is given here of the current scientific issues and the lessons learned since the beginning of CIAP, and it links the current research program with the assessment process that began two years ago.
Reduction of magneto rheological dampers stiffness by incorporating of an eddy current damper
NASA Astrophysics Data System (ADS)
Asghar Maddah, Ali; Hojjat, Yousef; Reza Karafi, Mohammad; Reza Ashory, Mohammad
2017-05-01
In this paper, a hybrid damper is developed to achieve lower stiffness compared to magneto rheological dampers. The hybrid damper consists of an eddy current damper (ECD) and a Magneto Rheological Damper (MRD). The aim of this research is to reduce the stiffness of MRDs with equal damping forces. This work is done by adding an eddy current passive damper to a semi-active MRD. The ECDs are contactless dampers which show an almost viscous damping behavior without increasing the stiffness of a system. However, MRDs increase damping and stiffness of a system simultaneously, when a magnetic field is applied. Damping of each part is studied theoretically and experimentally. A semi-empirical model is developed to explain the viscoelastic behavior of the damper. The experimental results showed that the hybrid damper is able to dissipate energy as much as those of MRDs while its stiffness is 12% lower at a zero excitation current.
Intracranial Pressure Monitoring—Review and Avenues for Development
Dolmans, Rianne G. F.
2018-01-01
Intracranial pressure (ICP) monitoring is a staple of neurocritical care. The most commonly used current methods of monitoring in the acute setting include fluid-based systems, implantable transducers and Doppler ultrasonography. It is well established that management of elevated ICP is critical for clinical outcomes. However, numerous studies show that current methods of ICP monitoring cannot reliably define the limit of the brain’s intrinsic compensatory capacity to manage increases in pressure, which would allow for proactive ICP management. Current work in the field hopes to address this gap by harnessing live-streaming ICP pressure-wave data and a multimodal integration with other physiologic measures. Additionally, there is continued development of non-invasive ICP monitoring methods for use in specific clinical scenarios. PMID:29401746
NASA Astrophysics Data System (ADS)
Dunn, Warwick B.
2008-03-01
The functional levels of biological cells or organisms can be separated into the genome, transcriptome, proteome and metabolome. Of these the metabolome offers specific advantages to the investigation of the phenotype of biological systems. The investigation of the metabolome (metabolomics) has only recently appeared as a mainstream scientific discipline and is currently developing rapidly for the study of microbial, plant and mammalian metabolomes. The metabolome pipeline or workflow encompasses the processes of sample collection and preparation, collection of analytical data, raw data pre-processing, data analysis and data storage. Of these processes the collection of analytical data will be discussed in this review with specific interest shown in the application of mass spectrometry in the metabolomics pipeline. The current developments in mass spectrometry platforms (GC-MS, LC-MS, DIMS and imaging MS) and applications of specific interest will be highlighted. The current limitations of these platforms and applications will be discussed with areas requiring further development also highlighted. These include the detectable coverage of the metabolome, the identification of metabolites and the process of converting raw data to biological knowledge.
Career Preparation: A Longitudinal, Process-Oriented Examination
Stringer, Kate; Kerpelman, Jennifer; Skorikov, Vladimir
2011-01-01
Preparing for an adult career through careful planning, choosing a career, and gaining confidence to achieve career goals is a primary task during adolescence and early adulthood. The current study bridged identity process literature and career construction theory (Savickas, 2005) by examining the commitment component of career adaptability, career preparation (i.e., career planning, career decision-making, and career confidence), from an identity process perspective (Luyckx, Goossens, & Soenens, 2006). Research has suggested that career preparation dimensions are interrelated during adolescence and early adulthood; however, what remains to be known is how each dimension changes over time and the interrelationships among the dimensions during the transition from high school. Drawing parallels between career preparation and identity development dimensions, the current study addressed these questions by examining the patterns of change in each career preparation dimension and parallel process models that tested associations among the slopes and intercepts of the career preparation dimensions. Results showed that the career preparation dimensions were not developing similarly over time, although each dimension was associated cross-sectionally and longitudinally with the other dimensions. Results also suggested that career planning and decision-making precede career confidence. The results of the current study supported career construction theory and showed similarities between the processes of career preparation and identity development. PMID:21804641
BWR Servicing and Refueling Improvement Program: Phase I summary report
DOE Office of Scientific and Technical Information (OSTI.GOV)
Perry, D.R.
1978-09-01
Under the U.S. Department of Energy sponsorship, General Electric Co. (GE) undertook a study of boiling water reactor (BWR) refueling outages for the purpose of recommending the development and demonstration of critical path time savings improvements. The Tennessee Valley Authority (TVA) joined the study as a subcontractor, providing monitoring assistance and making the Browns Ferry Site available for improvement demonstrations. Agreement was also reached with Georgia Power Co., Power Authority of the State of New York, and Commonwealth Edison Co. for monitoring and data collection at Hatch 1, FitzPatrick, and Quad Cities 1 nuclear plants, respectively. The objective was tomore » identify, develop, and demonstrate improved refueling, maintenance, and inspection procedures and equipment. The improvements recommended in this study are applicable to BWR nuclear plants currently in operation as well as those in the design and construction phases. The recommendations and outage information can be used as a basis to plan and conduct the first outages of new plants and to improve the planning and facilities of currently operating plants. Many of the recommendations can readily be incorporated in plants currently in the design and construction phases as well as in the design of future plants. Many of these recommended improvements can be implemented immediately by utilities without further technical development.« less
Deen, J L; Weber, M; Qazi, S; Fontaine, O
2003-01-01
The WHO has published guidelines for the inpatient management of severe malnutrition. A qualitative study in hospitals in developing countries is being conducted to document the re-organisation of the clinical ward and support services required to implement these guidelines and to gain an impression of the feasibility and sustainability of such a re-organisation. Following a postal survey of experts in the management of malnutrition in children in developing countries, hospitals were contacted and asked if they were interested to participate in the study. If so, they were requested to submit background information about admission patterns, the frequency of malnutrition, and current practice. Based on this information, hospitals are selected for a preliminary visit. Following this, and the final selection, a paediatrician conducts three visits to the study hospital over a one-year period to appraise the current practice, assist the health staff in recognising the strengths and shortcomings of their current management, help them find locally appropriate solutions, support the implementation process through a participatory approach and assess the outcome. A structured survey instrument is used to guide the assessment and identification of problems. Results of the first visit, which documents the existing situation, and changes identified by staff and implemented during the second visit are presented.
Career Preparation: A Longitudinal, Process-Oriented Examination.
Stringer, Kate; Kerpelman, Jennifer; Skorikov, Vladimir
2011-08-01
Preparing for an adult career through careful planning, choosing a career, and gaining confidence to achieve career goals is a primary task during adolescence and early adulthood. The current study bridged identity process literature and career construction theory (Savickas, 2005) by examining the commitment component of career adaptability, career preparation (i.e., career planning, career decision-making, and career confidence), from an identity process perspective (Luyckx, Goossens, & Soenens, 2006). Research has suggested that career preparation dimensions are interrelated during adolescence and early adulthood; however, what remains to be known is how each dimension changes over time and the interrelationships among the dimensions during the transition from high school. Drawing parallels between career preparation and identity development dimensions, the current study addressed these questions by examining the patterns of change in each career preparation dimension and parallel process models that tested associations among the slopes and intercepts of the career preparation dimensions. Results showed that the career preparation dimensions were not developing similarly over time, although each dimension was associated cross-sectionally and longitudinally with the other dimensions. Results also suggested that career planning and decision-making precede career confidence. The results of the current study supported career construction theory and showed similarities between the processes of career preparation and identity development.
Lenzenweger, Mark F
2010-08-01
Research on the nature and development of personality disorders has grown immensely over the past thirty years. A selective summary overview is given of the current status of the scientific study of the personality disorders from several perspectives, including the epidemiological, longitudinal, experimental psychopathology, and neurobehavioral perspectives. From this research, we now know that approximately 10 percent of the general population suffer from a diagnosable personality disorder. Moreover, contrary to nearly a century of theory and clinical pedagogy, modern longitudinal studies clearly suggest that personality disorders decrease in severity over time. The mechanisms by which this change occurs are not understood at present, though it is not likely that change in underlying normal personality systems drives the change in personality disorder. The methods of the experimental psychopathology laboratory, including neuroimaging approaches, are being brought to bear on the nature of personality disorders in efforts to relate neurobiological and neurocognitive functions to personality disorder symptomatology. A model that links personality disorder feature development to underlying, interacting brain-based neurobehavioral systems is reviewed in brief. Current issues and findings illustrative of these developments are given using borderline personality disorder as an exemplar. Finally, areas of intersection between psychoanalytic treatment approaches and the growing science of personality disorder are highlighted.
Water-waves on linear shear currents. A comparison of experimental and numerical results.
NASA Astrophysics Data System (ADS)
Simon, Bruno; Seez, William; Touboul, Julien; Rey, Vincent; Abid, Malek; Kharif, Christian
2016-04-01
Propagation of water waves can be described for uniformly sheared current conditions. Indeed, some mathematical simplifications remain applicable in the study of waves whether there is no current or a linearly sheared current. However, the widespread use of mathematical wave theories including shear has rarely been backed by experimental studies of such flows. New experimental and numerical methods were both recently developed to study wave current interactions for constant vorticity. On one hand, the numerical code can simulate, in two dimensions, arbitrary non-linear waves. On the other hand, the experimental methods can be used to generate waves with various shear conditions. Taking advantage of the simplicity of the experimental protocol and versatility of the numerical code, comparisons between experimental and numerical data are discussed and compared with linear theory for validation of the methods. ACKNOWLEDGEMENTS The DGA (Direction Générale de l'Armement, France) is acknowledged for its financial support through the ANR grant N° ANR-13-ASTR-0007.
METHOD DEVELOPMENT FOR THE DETERMINATION OF FORMALDEHYDE IN SAMPLES OF ENVIRONMENTAL ORIGIN
An analytical method was developed for the determination of formaldehyde in samples of environmental origin. After a review of the current literature, five candidate methods involving chemical derivatization were chosen for evaluation. The five derivatization reagents studied wer...
Microoptomechanical sensor for intracranial pressure monitoring
NASA Astrophysics Data System (ADS)
Andreeva, A. V.; Luchinin, V. V.; Lutetskiy, N. A.; Sergushichev, A. N.
2014-12-01
The main idea of this research is the development of microoptomechanical sensor for intracranial pressure monitoring. Currently, the authors studied the scientific and technical knowledge in this field, as well as develop and test a prototype of microoptomechanical sensor for intracranial pressure (ICP) monitoring.
Childhood Rituals and Executive Functions
ERIC Educational Resources Information Center
Tregay, Jenifer; Gilmour, Jane; Charman, Tony
2009-01-01
Repetitive and ritualistic behaviours (RRBs) are a feature of both typical and atypical development. While the cognitive correlates of these behaviours have been investigated in some neurodevelopmental conditions these links remain largely unexplored in typical development. The current study examined the relationship between RRBs and executive…
DOT National Transportation Integrated Search
1986-09-01
A standard accelerated weathering test using Dimethyl Sulfoxide (DMSO) was developed to simulate the chemical degradation of basaltic rocks. After a thorough study of the parameters affecting the current procedure, such as container geometry, aggrega...
Personal Pronouns and the Autistic Child.
ERIC Educational Resources Information Center
Fay, Warren H.
1979-01-01
Current theory and research in development of self and of language in autistic children is considered, with emphasis on studies of normal development of personal pronouns and the roles played in that process by listening, echoic memory, mitigated echolalia (recording), and person deixis. (Author)
DOE Office of Scientific and Technical Information (OSTI.GOV)
Arai, Kenji; Ebata, Shigeo
1997-07-01
This paper summarizes the current and anticipated use of the thermal-hydraulic and neutronic codes for the BWR transient and accident analyses in Japan. The codes may be categorized into the licensing codes and the best estimate codes for the BWR transient and accident analyses. Most of the licensing codes have been originally developed by General Electric. Some codes have been updated based on the technical knowledge obtained in the thermal hydraulic study in Japan, and according to the BWR design changes. The best estimates codes have been used to support the licensing calculations and to obtain the phenomenological understanding ofmore » the thermal hydraulic phenomena during a BWR transient or accident. The best estimate codes can be also applied to a design study for a next generation BWR to which the current licensing model may not be directly applied. In order to rationalize the margin included in the current BWR design and develop a next generation reactor with appropriate design margin, it will be required to improve the accuracy of the thermal-hydraulic and neutronic model. In addition, regarding the current best estimate codes, the improvement in the user interface and the numerics will be needed.« less
ERIC Educational Resources Information Center
Joyner, Barbara
2017-01-01
In 1 urban Tennessee school, students in Grades 3 through 5 had not met adequate yearly progress in reading for the past 5 years. The purpose of this case study was to explore teachers' perceptions of current district-recommended teaching practice in reading. The research questions related to current instructional strategies, teaching practices,…
New Currents in Education: A Preliminary Review. QuEST Paper 10.
ERIC Educational Resources Information Center
Bhaerman, Robert D.
This booklet describes nine "new currents" in education with the recommendation that local and state federations of the American Federation of Teachers create QuEST committees of teachers to study the implications of all these issues and develop statements and QuEST action programs on them as they relate to local and state situations. The issues…
A theoretical analysis of the current-voltage characteristics of solar cells
NASA Technical Reports Server (NTRS)
Fang, R. C. Y.; Hauser, J. R.
1977-01-01
The correlation of theoretical and experimental data is discussed along with the development of a complete solar cell analysis. The dark current-voltage characteristics, and the parameters for solar cells are analyzed. The series resistance, and impurity gradient effects on solar cells were studied, the effects of nonuniformities on solar cell performance were analyzed.
The "Family" Section in Current Elementary Social Studies Textbooks in China
ERIC Educational Resources Information Center
Zhao, Weiju; Zhang, Zhiping; Liu, Juan
2017-01-01
Family is the essential unit of society as well as the pupils' cradle for growing up. It is particularly significant to help pupils understand "family," then form a scientific concept of the family and develop a positive family sentiment. In the current primary school textbooks of "Morality and Life (Society)" (version of the…
Assessment of BSBA Students' Conversancy in Current Business Issues: A Case Study
ERIC Educational Resources Information Center
Hogan, Eileen A.; Maskulka, Therese A.; Kaminski, Kathleen A.
2014-01-01
In 2008, the faculty of the College of Business at Kutztown University developed a set of five learning goals for its BSBA program. In fall, 2011, the college's Assurance of Learning Committee began to pursue the assessment of the last of these goals: "BSBA graduates will be conversant in current business issues, including ethics, social…
Islam and Muslim Life in Current Bavarian Geography Textbooks
ERIC Educational Resources Information Center
Zecha, Stefanie; Popp, Stephan; Yasar, Aysun
2016-01-01
This paper investigates the Islam and Muslim life in German textbooks. The study is based on the analysis of current Geography textbooks in Bavarian secondary schools. As a first step, the authors developed a system for objective analysis of the textbooks that structures the content in categories. In a second step, the authors used the qualitative…
Nurture Groups in a Scottish Secondary School: Purpose, Features, Value and Areas for Development
ERIC Educational Resources Information Center
Kourmoulaki, Athina
2013-01-01
Nurture groups (NGs) are increasingly being established in Scottish secondary schools yet research in this context is limited. The current study explores the purpose, features and value of two NGs in a Scottish secondary school through interviewing current and former NG members, parents/carers, NG staff and other school staff. A thematic analysis…
ERIC Educational Resources Information Center
Hickey, Will
2001-01-01
Describes a study that surveyed current and perceived future employer-provided training practices among multinational corporations manufacturing companies in the Tianjin Economic Development Area (T.E.D.A.) of China. Highlights include labor market; human resources management in China; workforce productivity; and return on investment. (Author/LRW)
ERIC Educational Resources Information Center
Abdallah, Mahmoud M. S.
2014-01-01
At an age marked by the emergence of new literacies, vast technological developments, and social networking practices, language is currently approached from a pragmatic perspective that recognises its functional use to meet realistic communicative goals. Taking this into account, the present study sought to identify the functional writing skills…
Integrating multiple distribution models to guide conservation efforts of an endangered toad
Treglia, Michael L.; Fisher, Robert N.; Fitzgerald, Lee A.
2015-01-01
Species distribution models are used for numerous purposes such as predicting changes in species’ ranges and identifying biodiversity hotspots. Although implications of distribution models for conservation are often implicit, few studies use these tools explicitly to inform conservation efforts. Herein, we illustrate how multiple distribution models developed using distinct sets of environmental variables can be integrated to aid in identification sites for use in conservation. We focus on the endangered arroyo toad (Anaxyrus californicus), which relies on open, sandy streams and surrounding floodplains in southern California, USA, and northern Baja California, Mexico. Declines of the species are largely attributed to habitat degradation associated with vegetation encroachment, invasive predators, and altered hydrologic regimes. We had three main goals: 1) develop a model of potential habitat for arroyo toads, based on long-term environmental variables and all available locality data; 2) develop a model of the species’ current habitat by incorporating recent remotely-sensed variables and only using recent locality data; and 3) integrate results of both models to identify sites that may be employed in conservation efforts. We used a machine learning technique, Random Forests, to develop the models, focused on riparian zones in southern California. We identified 14.37% and 10.50% of our study area as potential and current habitat for the arroyo toad, respectively. Generally, inclusion of remotely-sensed variables reduced modeled suitability of sites, thus many areas modeled as potential habitat were not modeled as current habitat. We propose such sites could be made suitable for arroyo toads through active management, increasing current habitat by up to 67.02%. Our general approach can be employed to guide conservation efforts of virtually any species with sufficient data necessary to develop appropriate distribution models.
Gould, Natalie J; Lorencatto, Fabiana; Stanworth, Simon J; Michie, Susan; Prior, Maria E; Glidewell, Liz; Grimshaw, Jeremy M; Francis, Jill J
2014-07-29
Audits of blood transfusion demonstrate around 20% transfusions are outside national recommendations and guidelines. Audit and feedback is a widely used quality improvement intervention but effects on clinical practice are variable, suggesting potential for enhancement. Behavioural theory, theoretical frameworks of behaviour change and behaviour change techniques provide systematic processes to enhance intervention. This study is part of a larger programme of work to promote the uptake of evidence-based transfusion practice. The objectives of this study are to design two theoretically enhanced audit and feedback interventions; one focused on content and one on delivery, and investigate the feasibility and acceptability. Study A (Content): A coding framework based on current evidence regarding audit and feedback, and behaviour change theory and frameworks will be developed and applied as part of a structured content analysis to specify the key components of existing feedback documents. Prototype feedback documents with enhanced content and also a protocol, describing principles for enhancing feedback content, will be developed. Study B (Delivery): Individual semi-structured interviews with healthcare professionals and observations of team meetings in four hospitals will be used to specify, and identify views about, current audit and feedback practice. Interviews will be based on a topic guide developed using the Theoretical Domains Framework and the Consolidated Framework for Implementation Research. Analysis of transcripts based on these frameworks will form the evidence base for developing a protocol describing an enhanced intervention that focuses on feedback delivery. Study C (Feasibility and Acceptability): Enhanced interventions will be piloted in four hospitals. Semi-structured interviews, questionnaires and observations will be used to assess feasibility and acceptability. This intervention development work reflects the UK Medical Research Council's guidance on development of complex interventions, which emphasises the importance of a robust theoretical basis for intervention design and recommends systematic assessment of feasibility and acceptability prior to taking interventions to evaluation in a full-scale randomised study. The work-up includes specification of current practice so that, in the trials to be conducted later in this programme, there will be a clear distinction between the control (usual practice) conditions and the interventions to be evaluated.
NASA Astrophysics Data System (ADS)
Kanti Bera, Tushar
2018-03-01
Biological tissues are developed with biological cells which exhibit complex electrical impedance called electrical bioimpedance. Under an alternating electrical excitation the bioimpedance varies with the tissue anatomy, composition and the signal frequency. The current penetration and conduction paths vary with frequency of the applied signal. Bioimpedance spectroscopy is used to study the frequency response of the electrical impedance of biological materials noninvasively. In bioimpedance spectroscopy, a low amplitude electrical signal is injected to the tissue sample or body parts to characterization the sample in terms of its bioimpedance. The electrical current conduction phenomena, which is highly influenced by the tissue impedance and the signal frequency, is an important phenomena which should be studied to understand the bioimpedance techniques like bioelectrical impedance analysis (BIA), EIS, or else. In this paper the origin of bioelectrical impedance and current conduction phenomena has been reviewed to present a brief summary of bioelectrical impedance and the frequency dependent current conduction through biological tissues. Simulation studies are conducted with alternation current injection through a two dimensional model of biological tissues containing finite number of biological cells suspended in extracellular fluid. The paper demonstrates the simulation of alternating current conduction through biological tissues conducted by COMSOL Multiphysics. Simulation studies also show the frequency response of the tissue impedance for different tissue compositions.
Studies of the Superconducting Transition in the Mo/Au-Bilayer Thin Films
NASA Technical Reports Server (NTRS)
Sadleir, John; Smith, Stephen; Iyomoto, naoko; Bandler, Simon; Chervenak, Jay; Brown, Ari; Brekowsky, Regis; Kilbourne, Caroline; Robinson, Ian
2007-01-01
At NASA Goddard, microcalorimeter arrays using superconducting transition edge sensor thermometers (TESs) are under development for high energy resolution X-ray astrophysics applications. We report on our studies of the superconducting transition in our Mo/Au-bilayer TES films including: low current measurements of the superconducting bilayer's resistance transition versus temperature on pixels with different normal metal absorber attachment designs and measured temperature scaling of the critical current and critical magnetic field.
NASA Astrophysics Data System (ADS)
Tran, Jonathan
Plasma turbulence and the resulting anomalous electron transport due to azimuthal current driven instabilities in Hall-effect thrusters is a promising candidate for developing predictive models for the observed anomalous transport. A theory for anomalous electron transport and current driven instabilities has been recently studied by [Lafluer et al., 2016a]. Due to the extreme cost of fully resolving the Debye length and plasma frequency, hybrid plasma simulations utilizing kinetic ions and quasi-steady state fluid electrons have long been the principle workhorse methodology for Hall-effect thruster modeling. Using a reduced dimension particle in cell simulation implemented in the Thermophysics Universal Research Framework developed by the Air Force Research Lab, we show collective electron-wave scattering due to large amplitude azimuthal fluctuations of the electric field and the plasma density. These high-frequency and short wavelength fluctuations can lead to an effective cross-field mobility many orders of magnitude larger than what is expected from classical electron-neutral momentum collisions in the low neutral density regime. We further adapt the previous study by [Lampe et al., 1971] and [Stringer, 1964] for related current driven instabilities to electric propulsion relevant mass ratios and conditions. Finally, we conduct a preliminary study of resolving this instability with a modified hybrid simulation with the hope of integration with established hybrid Hall-effect thruster simulations.
NASA Astrophysics Data System (ADS)
Dhani, H. S.; Aminudin, A.; Waslaluddin
2018-05-01
Electric current is the basic variable of measurement in instrumentation system. One of the current measurements had been developed was based on magnetic sensor. Giant Magnetoresistance (GMR) produces an output voltage when it detects the magnetic field from electric current flow. The purpose of this study was to characterize the response of GMR when variation number of coil was given. The characterization was the GMR voltage response to the AC current values from 0.01 A to 5.00 A. The linearity of the relation was reaching saturation point when the magnetic field measured higher than 10.5 Oe at room temperature. As the number of coil increased, the earlier saturation occurred. To see the sensitivity of the sensor response, the data graph was cut off at 1.56 A AC. From this research, we got single coil was ideal to measure electric current higher than 1.56 A AC, as the relation of GMR voltage to the current tended to maintain its linearity. For measurement of 1.56 A AC and less, coil number addition would increase the sensitivity of sensor response. This research hopefully will be benefit for further development using an electric current measurement based on GMR magnetic sensor for power meter design.
Recent Developments in Low-Level Lead Exposure and Intellectual Impairment in Children
Koller, Karin; Brown, Terry; Spurgeon, Anne; Levy, Len
2004-01-01
In the last decade children’s blood lead levels have fallen significantly in a number of countries, and current mean levels in developed countries are in the region of 3 μg/dL. Despite this reduction, childhood lead poisoning continues to be a major public health problem for certain at-risk groups of children, and concerns remain over the effects of lead on intellectual development in infants and children. The evidence for lowered cognitive ability in children exposed to lead has come largely from prospective epidemiologic studies. The current World Health Organization/Centers for Disease Control and Prevention blood level of concern reflects this and stands at 10 μg/dL. However, a recent study on a cohort of children whose lifetime peak blood levels were consistently < 10 μg/dL has extended the association of blood lead and intellectual impairment to lower levels of lead exposure and suggests there is no safety margin at existing exposures. Because of the importance of this finding, we reviewed this study in detail along with other recent developments in the field of low-level lead exposure and children’s cognitive development. We conclude that these findings are important scientifically, and efforts should continue to reduce childhood exposure. However, from a public health perspective, exposure to lead should be seen within the many other risk factors impacting on normal childhood development, in particular the influence of the learning environment itself. Current lead exposure accounts for a very small amount of variance in cognitive ability (1–4%), whereas social and parenting factors account for 40% or more. PMID:15198918
ERIC Educational Resources Information Center
Kerr, Elizabeth E.; And Others
This sub-study of a 39-month longitudinal study conducted by the University of Illinois in cooperation with the University of Iowa, undertook to discern the trends in practical nursing in Iowa and to record a history of its development. The 435 member 10 percent random sample of practical nurses licensed in Iowa through December 1965, which was…
Study of DC Circuit Breaker of H2-N2 Mixture Gas for High Voltage
NASA Astrophysics Data System (ADS)
Shiba, Yuji; Morishita, Yukinaga; Kaneko, Shuhei; Okabe, Shigemitsu; Mizoguchi, Hitoshi; Yanabu, Satoru
Global warming caused by CO2 etc. is a field where the concern is very high. Especially, automobile emissions are problem for it. Therefore, the hybrid car is widely development and used recently. Hybrid car used electric power and gasoline. So, the car reduces CO2. Hybrid car has engine and motor. To rotate the motor, hybrid car has battery. This battery is large capacity. Therefore, the relay should interrupt high DC current for the switch of the motor and the engine. So, hybrid car used hydrogen gas filling relay We studied interruption test for the research of a basic characteristic of hydrogen gas. DC current has not current zero point. So, it is necessary to make the current zero by high arc voltage and forcible current zero point. The loss coefficient and arc voltage of hydrogen is high. Therefore, we studied interruption test for used high arc voltage. We studied interruption test and dielectric breakdown test of air, pure Hydrogen, and Hydrogen- nitrogen mixture gas. As a result, we realized H2-N2(80%-20%) is the best gas.
Tactical Combat Forces of the United States Air Force: Issues and Alternatives
1985-04-01
information if it does not display a currently valid OMB control number. 1. REPORT DATE APR 1985 2. REPORT TYPE 3. DATES COVERED 00-00-1985 to 00-00-1985...because of rounding. All costs are expressed in current dollars of budget authority, using the Administration’s February 1985 economic assumptions...plans and discusses the effects of current plans for fighter development on future forces. The study was re~ quested by the Defense Subcommittee of
Astrobiology from exobiology: Viking and the current Mars probes.
Soffen, G A
1997-01-01
The development of an Astrobiology Program is an extension of current exobiology programs. Astrobiology is the scientific study of the origin, distribution, evolution, and future of life in the universe. It encompasses exobiology; formation of elements, stars, planets, and organic molecules; initiation of replicating organisms; biological evolution; gravitational biology; and human exploration. Current interest in life on Mars provides the scientific community with an example of scientific inquiry that has mass appeal. Technology is mature enough to search for life in the universe.
ERIC Educational Resources Information Center
Nakayama, Shuichi
1989-01-01
Points out problems in planning a social studies curriculum that will prepare Japanese society for the 21st Century. Claiming that the current curricula is ethnocentric, looks at objectives and teaching strategies for developing a global approach. Recommends development of a global information network to increase awareness of the interrelatedness…
Teachers' Attitude towards ICT Use in Secondary Schools: A Scale Development Study
ERIC Educational Resources Information Center
Aydin, Mehmet Kemal; Semerci, Ali; Gürol, Mehmet
2016-01-01
The current study aims to develop a valid and reliable instrument that measures secondary school teachers' attitudes towards ICT use in teaching and learning process. A cross-sectional survey design was employed with a group of 173 teachers. Based on the literature review, a pool of 21 items was proposed and reviewed by a board of experts. As to…
ERIC Educational Resources Information Center
Ghoneim, Nahed Mohammed Mahmoud; Elghotmy, Heba Elsayed Abdelsalam
2015-01-01
The current study investigates the effect of a suggested multisensory phonics program on developing kindergarten pre-service teachers' EFL reading accuracy and phonemic awareness. A total of 40 fourth year kindergarten pre-service teachers, Faculty of Education, participated in the study that involved one group experimental design. Pre-post tests…
Development program on a cold cathode electron gun
NASA Technical Reports Server (NTRS)
Spindt, C. A.; Holland, C. E.
1985-01-01
During this phase of the cathode development program, SRI improved the multiple electron beam exposure system used to print hole patterns for the cathode arrays, studied anisotropic etch processes, conducted cathode investigations using an emission microscope, reviewed possible alternate materials for cathode fabrication, studied cathode storage techniques, conducted high power operation experiments, and demonstrated high-current-density operation with small arrays of tips.
The Impact of SimVenture on the Development of Entrepreneurial Skills in Management Students
ERIC Educational Resources Information Center
Williams, Dina
2015-01-01
The purpose of this study was to bridge a gap in our understanding of the role business simulation games can play in the development of entrepreneurial capabilities in undergraduate students. While entrepreneurship education has come a long way from being a branch of business and management studies, to its current status as a core discipline in…
ERIC Educational Resources Information Center
Herman, Jennifer H.
2013-01-01
This quantitative study reports data from nearly 200 teaching and learning development units (TLDUs), regarding their current staffing levels compared to the number of FTE faculty and FTE student enrollment. The study found that these staffing ratios at primary TLDUs vary by both institutional control and by Carnegie classification: in general,…
ERIC Educational Resources Information Center
Alkraiji, Abdullah; Jackson, Thomas; Murray, Ian
2011-01-01
Purpose: This paper seeks to carry out a critical study of health data standards and adoption process with a focus on Saudi Arabia. Design/methodology/approach: Many developed nations have initiated programs to develop, promote, adopt and customise international health data standards to the local needs. The current status of, and future plans for,…
ERIC Educational Resources Information Center
Epting, James B., Jr.
2013-01-01
The current study described and analyzed the perspectives of traditional-aged college student-athletes who participated in National Collegiate Athletic Association (NCAA) Division I football regarding the impact the sport had on Christian faith development. The study entailed a qualitative research method approach using in-depth semi-structured…
ERIC Educational Resources Information Center
Bay, Jacquie L.; Fohoko, Fehi; La'Akulu, Mumui; Leota, Ofa; Pulotu, Lesieli; Tu'Ipuloto, Sina; Tutoe, Salesi; Tovo, Oliveti; Vekoso, Ana; Pouvalu, Emeli H.
2016-01-01
Questioning is central to the development of scientific and health literacies. In exploring this concept, Tongan science teachers hypothesized that their ability to use and encourage questioning presented challenges in the context of Tongan social and cultural norms. This study set out to develop a peer-to-peer protocol to enable teachers to…
Community Colleges in the Commonwealth; A Report of a Survey.
ERIC Educational Resources Information Center
Blee, Myron R.; And Others
Since the Kentucky community college network has been in operation for several years, it was felt that a study of the current status and dimensions of that network would be useful in developing guidelines for future development. After visits to each of the schools and study of related data, it was noted that the community colleges are closely…
ERIC Educational Resources Information Center
Murray, Eileen; Durkin, Kelley; Chao, Theodore; Star, Jon R.; Vig, Rozy
2018-01-01
Past work on mathematics teachers' content knowledge (CK) and pedagogical content knowledge (PCK) has resulted in mixed findings about the strength of the relationship between and development of these constructs. The current study uses data from the Teacher Education and Development Study in Mathematics (TEDS-M) to examine the relationship between…
ERIC Educational Resources Information Center
Sims, Laura; Falkenberg, Thomas
2013-01-01
Education is paramount when trying to enable a change in values and attitudes towards sustainability. Higher education in faculties of education plays an important role in working toward this change because of its impact on future and practicing teachers in the school systems. This study inquires into the current role of education for sustainable…
ERIC Educational Resources Information Center
Lin, Su-ching; Wu, Ming-sui
2016-01-01
This study was the first year of a two-year project which applied a program theory-driven approach to evaluating the impact of teachers' professional development interventions on students' learning by using a mix of methods, qualitative inquiry, and quasi-experimental design. The current study was to show the results of using the method of…
Teacher Design Teams as a Strategy for Professional Development: The Role of the Facilitator
ERIC Educational Resources Information Center
Becuwe, Heleen; Tondeur, Jo; Pareja Roblin, Natalie; Thys, Jeroen; Castelein, Els
2016-01-01
The goal of the current study was to explore the role and importance of the facilitator in teacher design teams. The study took place in the context of a pre-service teacher education institution in Belgium, where teacher design teams were set up to facilitate the professional development of teacher educators. The findings from focus-group…
Studying the Brain in a Dish: 3D Cell Culture Models of Human Brain Development and Disease.
Brown, Juliana; Quadrato, Giorgia; Arlotta, Paola
2018-01-01
The study of the cellular and molecular processes of the developing human brain has been hindered by access to suitable models of living human brain tissue. Recently developed 3D cell culture models offer the promise of studying fundamental brain processes in the context of human genetic background and species-specific developmental mechanisms. Here, we review the current state of 3D human brain organoid models and consider their potential to enable investigation of complex aspects of human brain development and the underpinning of human neurological disease. © 2018 Elsevier Inc. All rights reserved.
Agriculture for improved nutrition: the current research landscape.
Turner, Rachel; Hawkes, Corinna; Jeff, Waage; Ferguson, Elaine; Haseen, Farhana; Homans, Hilary; Hussein, Julia; Johnston, Deborah; Marais, Debbi; McNeill, Geraldine; Shankar, Bhavani
2013-12-01
Concern about food security and its effect on persistent undernutrition has increased interest in how agriculture could be used to improve nutritional outcomes in developing countries. Yet the evidence base for the impact of agricultural interventions targeted at improved nutrition is currently poor. To map the extent and nature of current and planned research on agriculture for improved nutrition in order to identify gaps where more research might be useful. The research, which was conducted from April to August 2012, involved developing a conceptual framework linking agriculture and nutrition, identifying relevant research projects and programs, devising and populating a "template" with details of the research projects in relation to the conceptual framework, classifying the projects, and conducting a gap analysis. The study identified a large number of research projects covering a broad range of themes and topics. There was a strong geographic focus on sub-Saharan Africa, and many studies were explicitly concerned with nutritional impacts on women and children. Although the study revealed a diverse and growing body of research, it also identified research gaps. Few projects consider the entire evidence chain linking agricultural input or practice to nutritional outcomes. There is comparatively little current research on indirect effects of agriculture on nutrition, or the effect of policies or governance, rather than technical interventions. Most research is focused on undernutrition and small farmer households, and few studies target consumers generally, urban populations, or nutrition-related non-communicable diseases. There is very little work on the cost-effectiveness of agricultural interventions. On the basis of these findings, we make suggestions for research investment and for broader engagement of researchers and disciplines in developing approaches to design and evaluate agricultural programs for improved nutrition.
Wang, Yi; Lee, Sui Mae; Dykes, Gary
2015-01-01
Bacterial attachment to abiotic surfaces can be explained as a physicochemical process. Mechanisms of the process have been widely studied but are not yet well understood due to their complexity. Physicochemical processes can be influenced by various interactions and factors in attachment systems, including, but not limited to, hydrophobic interactions, electrostatic interactions and substratum surface roughness. Mechanistic models and control strategies for bacterial attachment to abiotic surfaces have been established based on the current understanding of the attachment process and the interactions involved. Due to a lack of process control and standardization in the methodologies used to study the mechanisms of bacterial attachment, however, various challenges are apparent in the development of models and control strategies. In this review, the physicochemical mechanisms, interactions and factors affecting the process of bacterial attachment to abiotic surfaces are described. Mechanistic models established based on these parameters are discussed in terms of their limitations. Currently employed methods to study these parameters and bacterial attachment are critically compared. The roles of these parameters in the development of control strategies for bacterial attachment are reviewed, and the challenges that arise in developing mechanistic models and control strategies are assessed.
Current state-of-art of STR sequencing in forensic genetics.
Alonso, Antonio; Barrio, Pedro A; Müller, Petra; Köcher, Steffi; Berger, Burkhard; Martin, Pablo; Bodner, Martin; Willuweit, Sascha; Parson, Walther; Roewer, Lutz; Budowle, Bruce
2018-05-11
The current state of validation and implementation strategies of MPS technology for the analysis of STR markers for forensic genetics use is described, covering the topics of the current catalogue of commercial MPS-STR panels, leading MPS-platforms, and MPS-STR data analysis tools. In addition, the developmental and internal validation studies carried out to date to evaluate reliability, sensitivity, mixture analysis, concordance, and the ability to analyze challenged samples are summarized. The results of various MPS-STR population studies that showed a large number of new STR sequence variants that increase the power of discrimination in several forensically-relevant loci are also presented. Finally, various initiatives developed by several international projects and standardization (or guidelines) groups to facilitate application of MPS technology for STR marker analyses are discussed in regard to promoting a standard STR sequence nomenclature, performing population studies to detect sequence variants, and developing a universal system to translate sequence variants into a simple STR nomenclature (numbers and letters) compatible with national STR databases. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.
2014-01-01
Background The utilisation of good design practices in the development of complex health services is essential to improving quality. Healthcare organisations, however, are often seriously out of step with modern design thinking and practice. As a starting point to encourage the uptake of good design practices, it is important to understand the context of their intended use. This study aims to do that by articulating current health service development practices. Methods Eleven service development projects carried out in a large mental health service were investigated through in-depth interviews with six operation managers. The critical decision method in conjunction with diagrammatic elicitation was used to capture descriptions of these projects. Stage-gate design models were then formed to visually articulate, classify and characterise different service development practices. Results Projects were grouped into three categories according to design process patterns: new service introduction and service integration; service improvement; service closure. Three common design stages: problem exploration, idea generation and solution evaluation - were then compared across the design process patterns. Consistent across projects were a top-down, policy-driven approach to exploration, underexploited idea generation and implementation-based evaluation. Conclusions This study provides insight into where and how good design practices can contribute to the improvement of current service development practices. Specifically, the following suggestions for future service development practices are made: genuine user needs analysis for exploration; divergent thinking and innovative culture for idea generation; and fail-safe evaluation prior to implementation. Better training for managers through partnership working with design experts and researchers could be beneficial. PMID:24438471
Jun, Gyuchan Thomas; Morrison, Cecily; Clarkson, P John
2014-01-17
The utilisation of good design practices in the development of complex health services is essential to improving quality. Healthcare organisations, however, are often seriously out of step with modern design thinking and practice. As a starting point to encourage the uptake of good design practices, it is important to understand the context of their intended use. This study aims to do that by articulating current health service development practices. Eleven service development projects carried out in a large mental health service were investigated through in-depth interviews with six operation managers. The critical decision method in conjunction with diagrammatic elicitation was used to capture descriptions of these projects. Stage-gate design models were then formed to visually articulate, classify and characterise different service development practices. Projects were grouped into three categories according to design process patterns: new service introduction and service integration; service improvement; service closure. Three common design stages: problem exploration, idea generation and solution evaluation - were then compared across the design process patterns. Consistent across projects were a top-down, policy-driven approach to exploration, underexploited idea generation and implementation-based evaluation. This study provides insight into where and how good design practices can contribute to the improvement of current service development practices. Specifically, the following suggestions for future service development practices are made: genuine user needs analysis for exploration; divergent thinking and innovative culture for idea generation; and fail-safe evaluation prior to implementation. Better training for managers through partnership working with design experts and researchers could be beneficial.
Growth of a Species, an Association, a Science: 80 Years of Growth and Development Research
Sherwood, Richard J.; Duren, Dana L.
2014-01-01
Physical anthropological research was codified in the United States with the creation of the American Association of Physical Anthropology (AAPA) in 1929. That same year, a study began in yellow springs, Ohio, with a goal of identifying “what makes people different.” The approach used to answer that question was to study the growth and development of Homo sapiens. The resulting study, the Fels Longitudinal Study, is currently the longest continuous study of human growth and development in the world. Although the AAPA and the Fels Longitudinal Study have existed as separate entities for more than 80 years now, it is not surprising, given the relationship between anatomical and developmental research, there has been considerable overlap between the two. As the field of physical anthropology has blossomed to include subdisciplines such as forensics, genetics, primatology, as well as sophisticated statistical methodologies, the importance of growth and development research has escalated. Although current Fels Longitudinal Study research is largely directed at biomedical questions, virtually all findings are relevant to physical anthropology, providing insights into basic biological processes and life history parameters. Some key milestones from the early years of the AAPA and the Fels Longitudinal Study are highlighted here that address growth and development research in physical anthropology. These are still held as fundamental concepts that underscore the importance of this line of inquiry, not only across the subdisciplines of physical anthropology, but also among anthropological, biological, and biomedical inquiries. PMID:23283658
Growth of a species, an association, a science: 80 years of growth and development research.
Sherwood, Richard J; Duren, Dana L
2013-01-01
Physical anthropological research was codified in the United States with the creation of the American Association of Physical Anthropology (AAPA) in 1929. That same year, a study began in yellow springs, Ohio, with a goal of identifying "what makes people different." The approach used to answer that question was to study the growth and development of Homo sapiens. The resulting study, the Fels Longitudinal Study, is currently the longest continuous study of human growth and development in the world. Although the AAPA and the Fels Longitudinal Study have existed as separate entities for more than 80 years now, it is not surprising, given the relationship between anatomical and developmental research, there has been considerable overlap between the two. As the field of physical anthropology has blossomed to include subdisciplines such as forensics, genetics, primatology, as well as sophisticated statistical methodologies, the importance of growth and development research has escalated. Although current Fels Longitudinal Study research is largely directed at biomedical questions, virtually all findings are relevant to physical anthropology, providing insights into basic biological processes and life history parameters. Some key milestones from the early years of the AAPA and the Fels Longitudinal Study are highlighted here that address growth and development research in physical anthropology. These are still held as fundamental concepts that underscore the importance of this line of inquiry, not only across the subdisciplines of physical anthropology, but also among anthropological, biological, and biomedical inquiries. Copyright © 2012 Wiley Periodicals, Inc.
Domain wall dynamics driven by spin transfer torque and the spin-orbit field.
Hayashi, Masamitsu; Nakatani, Yoshinobu; Fukami, Shunsuke; Yamanouchi, Michihiko; Mitani, Seiji; Ohno, Hideo
2012-01-18
We have studied current-driven dynamics of domain walls when an in-plane magnetic field is present in perpendicularly magnetized nanowires using an analytical model and micromagnetic simulations. We model an experimentally studied system, ultrathin magnetic nanowires with perpendicular anisotropy, where an effective in-plane magnetic field is developed when current is passed along the nanowire due to the Rashba-like spin-orbit coupling. Using a one-dimensional model of a domain wall together with micromagnetic simulations, we show that the existence of such in-plane magnetic fields can either lower or raise the threshold current needed to cause domain wall motion. In the presence of the in-plane field, the threshold current differs for positive and negative currents for a given wall chirality, and the wall motion becomes sensitive to out-of-plane magnetic fields. We show that large non-adiabatic spin torque can counteract the effect of the in-plane field.
Drag and Lift Forces Between a Rotating Conductive Sphere and a Cylindrical Magnet
NASA Technical Reports Server (NTRS)
Nurge, Mark A.; Youngquist, Robert C.
2017-01-01
Modeling the interaction between a non-uniform magnetic field and a rotating conductive object allows study of the drag force which is used in applications such as eddy current braking and linear induction motors as well as the transition to a repulsive force that is the basis for magnetic levitation systems. Here, we study the interaction between a non-uniform field generated by a cylindrical magnet and a rotating conductive sphere. Each eddy current in the sphere generates a magnetic field which in turn generates another eddy current, eventually feeding back on itself. A two step mathematics process is developed to find a closed form solution in terms of only two eddy currents. However, the complete solution requires decomposition of the magnetic field into a summation of spherical harmonics, making it more suitable for a graduate level electromagnetism lecture or lab. Finally, the forces associated with these currents are calculated and then verified experimentally.
Jet behaviors and ejection mode recognition of electrohydrodynamic direct-write
NASA Astrophysics Data System (ADS)
Zheng, Jianyi; Zhang, Kai; Jiang, Jiaxin; Wang, Xiang; Li, Wenwang; Liu, Yifang; Liu, Juan; Zheng, Gaofeng
2018-01-01
By introducing image recognition and micro-current testing, jet behavior research was conducted, in which the real-time recognition of ejection mode was realized. To study the factors influencing ejection modes and the current variation trends under different modes, an Electrohydrodynamic Direct-Write (EDW) system with functions of current detection and ejection mode recognition was firstly built. Then a program was developed to recognize the jet modes. As the voltage applied to the metal tip increased, four jet ejection modes in EDW occurred: droplet ejection mode, Taylor cone ejection mode, retractive ejection mode and forked ejection mode. In this work, the corresponding relationship between the ejection modes and the effect on fiber deposition as well as current was studied. The real-time identification of ejection mode and detection of electrospinning current was realized. The results in this paper are contributed to enhancing the ejection stability, providing a good technical basis to produce continuous uniform nanofibers controllably.
NASA Astrophysics Data System (ADS)
Yousefi, Taher; Torab-Mostaedi, Meisam; Mobtaker, Hossein Ghasemi; Keshtkar, Ali Reza
2016-10-01
The strategy developed in this study, offers significant advantages (simplicity and cleanness of method and also a product purity and new morphology of the product) over the conventional routes for the synthesis of ThO2 nanostructure. The effect of current density on morphology was studied. The synthesized powder was characterized by means of Powder X-ray Diffraction (PXRD), Transmission Electron Microscopy (TEM, Phillips EM 2085) Brunauer-Emmett-Teller (BET) and Fourier Transform Infrared (FT-IR) spectroscopy. The results show that the current density has a great effect on the morphology of the samples. The average size of the particles decreases as the applied current density increases and the average size of the samples decreases from 50 to 15 nm when the current density increases from 2 to 5 mA cm-2.
NASA Technical Reports Server (NTRS)
Reynolds, Thomas L.; Bailey, Delbert B.; Lewinski, Daniel F.; Roseburg, Conrad M.; Palaszewski, Bryan (Technical Monitor)
2001-01-01
The purpose of this technology assessment is to define a multiphase research study program investigating Onboard Inert Gas Generation Systems (OBIGGS) and Onboard Oxygen Generation Systems (OBOGS) that would identify current airplane systems design and certification requirements (Subtask 1); explore state-of-the-art technology (Subtask 2); develop systems specifications (Subtask 3); and develop an initial system design (Subtask 4). If feasible, consideration may be given to the development of a prototype laboratory test system that could potentially be used in commercial transport aircraft (Subtask 5). These systems should be capable of providing inert nitrogen gas for improved fire cargo compartment fire suppression and fuel tank inerting and emergency oxygen for crew and passenger use. Subtask I of this research study, presented herein, defines current production aircraft certification requirements and design objectives necessary to meet mandatory FAA certification requirements and Boeing design and performance specifications. These requirements will be utilized for baseline comparisons for subsequent OBIGGS/OBOGS application evaluations and assessments.
hPSC-derived lung and intestinal organoids as models of human fetal tissue
Aurora, Megan; Spence, Jason R.
2016-01-01
In vitro human pluripotent stem cell (hPSC) derived tissues are excellent models to study certain aspects of normal human development. Current research in the field of hPSC derived tissues reveals these models to be inherently fetal-like on both a morphological and gene expression level. In this review we briefly discuss current methods for differentiating lung and intestinal tissue from hPSCs into individual 3-dimensional units called organoids. We discuss how these methods mirror what is known about in vivo signaling pathways of the developing embryo. Additionally, we will review how the inherent immaturity of these models lends them to be particularly valuable in the study of immature human tissues in the clinical setting of premature birth. Human lung organoids (HLOs) and human intestinal organoids (HIOs) not only model normal development, but can also be utilized to study several important diseases of prematurity such as respiratory distress syndrome (RDS), bronchopulmonary dysplasia (BPD), and necrotizing enterocolitis (NEC). PMID:27287882
Application of Risk within Net Present Value Calculations for Government Projects
NASA Technical Reports Server (NTRS)
Grandl, Paul R.; Youngblood, Alisha D.; Componation, Paul; Gholston, Sampson
2007-01-01
In January 2004, President Bush announced a new vision for space exploration. This included retirement of the current Space Shuttle fleet by 2010 and the development of new set of launch vehicles. The President's vision did not include significant increases in the NASA budget, so these development programs need to be cost conscious. Current trade study procedures address factors such as performance, reliability, safety, manufacturing, maintainability, operations, and costs. It would be desirable, however, to have increased insight into the cost factors behind each of the proposed system architectures. This paper reports on a set of component trade studies completed on the upper stage engine for the new launch vehicles. Increased insight into architecture costs was developed by including a Net Present Value (NPV) method and applying a set of associated risks to the base parametric cost data. The use of the NPV method along with the risks was found to add fidelity to the trade study and provide additional information to support the selection of a more robust design architecture.
Rao, Yuefeng; Zhao, Qingwei; Zhang, Xiangyi; Yang, Hongyu; Lou, Yan; Zhang, Xingguo
2016-03-01
In many industrialized countries, clinical pharmacy has developed into a separate discipline and become a vital part of inpatient care in hospitals. However, as compared to many established branches of medicine, clinical pharmacy is still in its infancy, with much room for growth, improvement, and recognition by both the medical community and patients. In this study, a widely-recognized development strategy analysis tool, Strength, Weakness, Opportunity and Threat (SWOT), was used to systematically address several key issues to the development of clinical pharmacy in China. This analysis aims to provide feasible recommendations for the development of clinical pharmacy in China by identifying current problems and growth opportunities. Full development of clinical pharmacy as a mature clinical discipline will help promote the rational use of drugs by both clinicians and patients and lead to enhanced drug efficacy and safety.
The development of scientific reasoning in medical education: a psychological perspective.
Barz, Daniela Luminita; Achimaş-Cadariu, Andrei
2016-01-01
Scientific reasoning has been studied from a variety of theoretical perspectives, which have tried to identify the underlying mechanisms responsible for the development of this particular cognitive process. Scientific reasoning has been defined as a problem-solving process that involves critical thinking in relation to content, procedural, and epistemic knowledge. The development of scientific reasoning in medical education was influenced by current paradigmatic trends, it could be traced along educational curriculum and followed cognitive processes. The purpose of the present review is to discuss the role of scientific reasoning in medical education and outline educational methods for its development. Current evidence suggests that medical education should foster a new ways of development of scientific reasoning, which include exploration of the complexity of scientific inquiry, and also take into consideration the heterogeneity of clinical cases found in practice.
Technology for small spacecraft
NASA Technical Reports Server (NTRS)
1994-01-01
This report gives the results of a study by the National Research Council's Panel on Small Spacecraft Technology that reviewed NASA's technology development program for small spacecraft and assessed technology within the U.S. government and industry that is applicable to small spacecraft. The panel found that there is a considerable body of advanced technology currently available for application by NASA and the small spacecraft industry that could provide substantial improvement in capability and cost over those technologies used for current NASA small spacecraft. These technologies are the result of developments by commercial companies, Department of Defense agencies, and to a lesser degree NASA. The panel also found that additional technologies are being developed by these same entities that could provide additional substantial improvement if development is successfully completed. Recommendations for future technology development efforts by NASA across a broad technological spectrum are made.
NASA Technical Reports Server (NTRS)
Griesel, Martha Ann
1988-01-01
Several Laboratory software development projects that followed nonstandard development processes, which were hybrids of incremental development and prototyping, are being studied. Factors in the project environment leading to the decision to use a nonstandard development process and affecting its success are analyzed. A simple characterization of project environment based on this analysis is proposed, together with software development approaches which have been found effective for each category. These approaches include both documentation and review requirements.
Diffusion of Technical Agricultural Information in Chile.
ERIC Educational Resources Information Center
Brown, Marion Ray
This study examined current thought concerning the role of mass communication in economic development in developing nations; analyzed existing efforts to diffuse agricultural technology in Chile; assessed the effectiveness of various approaches; and tested the effects (primarily on knowledge levels) of an experimental technical information service…
The Potential of Directed Instruction to Teach Effectively Technology Usage
ERIC Educational Resources Information Center
Hosseini, Zahra
2016-01-01
Currently, teacher educational systems tend to develop their teachers' knowledge to effectively integrate technology in teaching. Consequently, numerous studies have attempted to describe strategies, models and approaches to develop teachers' knowledge for teaching with technology. However, most teachers are still following their traditional…
ABSTRACT In the current study, we developed a new system using full-length recombinant baculovirus-expressed estrogen receptors which allows for direct comparison of binding across species. Estrogen receptors representing five vertebrate classes were compared: human (hERα), quai...
DOT National Transportation Integrated Search
1998-05-01
State transportation agencies commonly use consultant firms for some of their highway and bridge design. For example, the Louisiana Department of Transportation and Development (hereafter referred to as the "Department" or "LaDOTD") currently uses bo...
The Business Practices Course: Self-Study Learning Reengineered.
ERIC Educational Resources Information Center
Acovelli, Marianne; Nowakowski, Alan
1994-01-01
Describes an interactive multimedia Business Practices Course, developed to help reengineer point-of-need training for professional development, in which the learner conducts a business review of a company's current operations and makes recommendations to improve productivity and increase customer satisfaction. (six references) (LRW)
Santos, Michele Devido; Gagliardi, Rubens José; Mac-Kay, Ana Paula Machado Goyano; Boggio, Paulo Sergio; Lianza, Roberta; Fregni, Felipe
2013-01-01
Previous animal and human studies have shown that transcranial direct current stimulation can induce significant and lasting neuroplasticity and may improve language recovery in patients with aphasia. The objective of the study was to describe a cohort of patients with aphasia after stroke who were treated with transcranial direct current stimulation. Prospective cohort study developed in a public university hospital. Nineteen patients with chronic aphasia received 10 transcranial direct current stimulation sessions lasting 20 minutes each on consecutive days, using a current of 2 mA. The anode was positioned over the supraorbital area and the cathode over the contralateral motor cortex. The following variables were analyzed before and after the 10 neuromodulation sessions: oral language comprehension, copying, dictation, reading, writing, naming and verbal fluency. There were no adverse effects in the study. We found statistically significant differences from before to after stimulation in relation to simple sentence comprehension (P = 0.034), naming (P = 0.041) and verbal fluency for names of animals (P = 0.038). Improved scores for performing these three tasks were seen after stimulation. We observed that excitability of the primary motor cortex through transcranial direct current stimulation was associated with effects on different aspects of language. This can contribute towards future testing in randomized controlled trials.
NASA Astrophysics Data System (ADS)
Koujalagi, V.; Ramesh, S. L.; Gunarathne, G. P. P.; Semple, S.; Ayres, J. G.
2009-02-01
This study presents the work carried out in developing a precision bolus injection system in order to understand the regional deposition of nanoparticles (NP) in human lung. A real-time control system has been developed that is capable of storing graphite NP, assessing human breathing pattern and delivering a bolus of the stored NP at a pre-determined instance of the inhalation phase of breathing. This will form the basis for further development of a system to deliver radioactive nanoparticles to enable 3-dimensional lung imaging using techniques such as positron emission tomography (PET). The system may then be used to better understand the actual regional deposition in human lung, which could validate or challenge the current computational lung models such as that published by the International Commission for Radiation Protection (ICRP-1994). A dose related response to inhaled PM can possibly be shown, which can be used to review the current workplace exposure limits (WELs).
Current State of Agile User-Centered Design: A Survey
NASA Astrophysics Data System (ADS)
Hussain, Zahid; Slany, Wolfgang; Holzinger, Andreas
Agile software development methods are quite popular nowadays and are being adopted at an increasing rate in the industry every year. However, these methods are still lacking usability awareness in their development lifecycle, and the integration of usability/User-Centered Design (UCD) into agile methods is not adequately addressed. This paper presents the preliminary results of a recently conducted online survey regarding the current state of the integration of agile methods and usability/UCD. A world wide response of 92 practitioners was received. The results show that the majority of practitioners perceive that the integration of agile methods with usability/UCD has added value to their adopted processes and to their teams; has resulted in the improvement of usability and quality of the product developed; and has increased the satisfaction of the end-users of the product developed. The top most used HCI techniques are low-fidelity prototyping, conceptual designs, observational studies of users, usability expert evaluations, field studies, personas, rapid iterative testing, and laboratory usability testing.
Pluripotent stem cell-derived natural killer cells for cancer therapy
Knorr, David A.; Kaufman, Dan S.
2010-01-01
Human embryonic stem cells (hESCs) and induced pluripotent stem cells (iPSCs) provide an accessible, genetically tractable and homogenous starting cell populations to efficiently study human blood cell development. These cell populations provide platforms to develop new cell-based therapies to treat both malignant and non-malignant hematological diseases. Our group has previously demonstrated the ability of hESC-derived hematopoietic precursors to produce functional natural killer (NK) cells as well as an explanation of the underlying mechanism responsible for inefficient development of T and B cells from hESCs. hESCs and iPSCs, which can be reliably engineered in vitro, provide an important new model system to study human lymphocyte development and produce enhanced cell-based therapies with potential to serve as a “universal” source of anti-tumor lymphocytes for novel clinical therapies. This review will focus on the application of hESC-derived NK cells with currently used and novel therapeutics for clinical trials, current barriers to translation, and future applications through genetic engineering approaches. PMID:20801411
Photovoltaic power for Space Station Freedom
NASA Technical Reports Server (NTRS)
Baraona, Cosmo R.
1990-01-01
Space Station Freedom is described with special attention given to its electric power system. The photovoltaic arrays, the battery energy storage system, and the power management, and distribution system are also discussed. The current design of Freedom's power system and the system requirements, trade studies, and competing factors which lead to system selections are referenced. This will be the largest power system ever flown in space. This system represents the culmination of many developments that have improved system performance, reduced cost, and improved reliability. Key developments and their evolution into the current space station solar array design are briefly described. The features of the solar cell and the array including the development, design, test, and flight hardware production status are given.
Photovoltaic power for Space Station Freedom
NASA Technical Reports Server (NTRS)
Baraona, Cosmo R.
1990-01-01
Space Station Freedom is described with special attention to its electric power system. The photovoltaic arrays, the battery energy storage system, and the power management and distribution system are also discussed. The current design of Freedom's power system and the system requirements, trade studies, and competing factors which lead to system selections are referenced. This will be the largest power system ever flown in space. This system represents the culmination of many developments that have improved system performance, reduced cost, and improved reliability. Key developments and their evolution into the current space station solar array design are briefly described. The features of the solar cell and the array including the development, design, test, and flight hardware production status are given.
NASA Radiation Protection Research for Exploration Missions
NASA Technical Reports Server (NTRS)
Wilson, John W.; Cucinotta, Francis A.; Tripathi, Ram K.; Heinbockel, John H.; Tweed, John; Mertens, Christopher J.; Walker, Steve A.; Blattnig, Steven R.; Zeitlin, Cary J.
2006-01-01
The HZETRN code was used in recent trade studies for renewed lunar exploration and currently used in engineering development of the next generation of space vehicles, habitats, and EVA equipment. A new version of the HZETRN code capable of simulating high charge and energy (HZE) ions, light-ions and neutrons with either laboratory or space boundary conditions with enhanced neutron and light-ion propagation is under development. Atomic and nuclear model requirements to support that development will be discussed. Such engineering design codes require establishing validation processes using laboratory ion beams and space flight measurements in realistic geometries. We discuss limitations of code validation due to the currently available data and recommend priorities for new data sets.
Automated inspection of turbine blades: Challenges and opportunities
NASA Technical Reports Server (NTRS)
Mehta, Manish; Marron, Joseph C.; Sampson, Robert E.; Peace, George M.
1994-01-01
Current inspection methods for complex shapes and contours exemplified by aircraft engine turbine blades are expensive, time-consuming and labor intensive. The logistics support of new manufacturing paradigms such as integrated product-process development (IPPD) for current and future engine technology development necessitates high speed, automated inspection of forged and cast jet engine blades, combined with a capability of retaining and retrieving metrology data for process improvements upstream (designer-level) and downstream (end-user facilities) at commercial and military installations. The paper presents the opportunities emerging from a feasibility study conducted using 3-D holographic laser radar in blade inspection. Requisite developments in computing technologies for systems integration of blade inspection in production are also discussed.
Gestational bisphenol A exposure and testis development.
Williams, Cecilia; Bondesson, Maria; Krementsov, Dimitry N; Teuscher, Cory
Virtually all humans are exposed to bisphenol A (BPA). Since BPA can act as a ligand for estrogen receptors, potential hazardous effects of BPA should be evaluated in the context of endogenous estrogenic hormones. Because estrogen is metabolized in the placenta, developing fetuses are normally exposed to very low endogenous estrogen levels. BPA, on the other hand, passes through the placenta and might have distinct adverse consequences during the sensitive stages of fetal development. Testicular gametogenesis and steroidogenesis begin early during fetal development. These processes are sensitive to estrogens and play a role in determining the number of germ stem cells, sperm count, and male hormone levels in adulthood. Although studies have shown a correlation between BPA exposure and perturbed reproduction, a clear consensus has yet to be established as to whether current human gestational BPA exposure results in direct adverse effects on male genital development and reproduction. However, studies in animals and in vitro have provided direct evidence for the ability of BPA exposure to influence male reproductive development. This review discusses the current knowledge of potential effects of BPA exposure on male reproductive health and whether gestational exposure adversely affects testis development.
NASA Astrophysics Data System (ADS)
Shen, Yi
This study investigated research meteorologists' current usage and evaluation of information and communication technologies (ICT) in performing research tasks and the current relationship between meteorologists' ICT use and content characteristics of their research outputs. It surveyed research meteorologists working in three NOAA funded research institutes based at universities. Follow-up interviews with two selective samples of the survey participants were conducted to provide additional evidence to survey results and make suggestions for future measurement development work. Multiple regression analysis was performed to test the hypothesized relationships between meteorologists' ICT use and two substantive characteristics of their research---data integration and intra-/interdisciplinarity. Descriptive statistics were calculated to discern inferences of the scientists' current state of use and their degree of satisfaction with ICT tools. Follow-up interviews were transcribed and analyzed qualitatively with open coding and axial coding. The study findings contradicted the two assumptions of ICT effects on meteorological research by showing that the greater frequency of networked ICT use is not significantly associated with either greater data integration in research analysis, or greater intra- or interdisciplinary research. The major ICT barrier is the lack of a data and information infrastructure and support system for integrated, standardized, specialized, and easily accessible data and information from distributed servers. Suggestions were provided on the improvements of technical, social, political, and educational settings to promote large-scale date integration and intra-/interdisciplinary research. By moving further from theoretical assumptions to practical examinations, the research findings provide empirical evidence of Bowker's theories on the social shaping and social impact of infrastructure in sciences and affirmed some of Bowker's arguments regarding both social-political aspect and technical aspect of e-science practice. The results also provide implications for Computer-Mediated-Communication theories. The knowledge helps information system developers identify several important issues in current systems planning and development. The study also helps librarians, information scientists, and meteorologists both recognize the importance of and develop their collaboration in data, information, and knowledge management. Finally, the study could aid research institutes and government funding agencies to develop appropriate strategies to optimize the effective use of ICT resources and augment its positive impact on sciences.
ERIC Educational Resources Information Center
Kiel, Elizabeth J.; Buss, Kristin A.
2010-01-01
Previous research has suggested that mothers' behaviors may serve as a mechanism in the development from toddler fearful temperament to childhood anxiety. The current study examined the maternal characteristic of accuracy in predicting toddlers' distress reactions to novelty in relation to temperament, parenting, and anxiety development.…
The Ultimate Impacts for Thai Teachers: Teachers Development System in Learning Management
ERIC Educational Resources Information Center
Boonmak, Thikamporn; Tesaputa, Kowat; Duangpaeng, Amparn
2015-01-01
This research was aimed to: (1) study current conditions, problems, and needs of teachers for development and learning management in the extended educational opportunities schools (EEOSs: schools where they extended fundamental education from primary level of six years to lower secondary level of nine years), in Thailand; (2) develop the system of…
The Development and Testing of a New Measure of Early Childhood Education Organizational Conditions
ERIC Educational Resources Information Center
Ehrlich, Stacy B.; Pacchiano, Debra M.; Luppescu, Stuart; Stein, Amanda
2016-01-01
The current study sought to scientifically adapt the existing five essentials teacher survey and develop a new parent survey, and pilot test them for use in early childhood education settings. The adaptation and development of these "Early Education Surveys" occurred in 2014-15, was based strongly on Bryk et al.'s (2010) existing…
ERIC Educational Resources Information Center
Bocciardi, Federica; Caputo, Andrea; Fregonese, Chiara; Langher, Viviana; Sartori, Riccardo
2017-01-01
Purpose: In the current labour market, the competence to adapt is becoming significantly relevant for career development and career success. The construct of career adaptability, i.e. the capability to adapt to changing career-related circumstances and predict advancement in career development, seems to provide a fruitful scientific base for…
The Structural and Conceptual Model of Development of Leadership in Junior School Children
ERIC Educational Resources Information Center
Turgunbaeva, Botagul A.; Aspanova, Gulmira R.; Gelisli, Yucel
2016-01-01
This study addresses a problem that is currently relevant for the modern society--the development of leadership. It attempts to analyze theoretically the literary sources that cover the development of leadership. The authors give their opinion on the general leadership theory, which regards leadership as a two-subject phenomenon, give their…
Adjunct Experiences with and Perceptions of Professional Development at a Texas Community College
ERIC Educational Resources Information Center
Miles, R. Mark
2017-01-01
Universities and colleges have developed an over-reliance on adjunct faculty, and as a result, researchers have begun to study adjunct faculty satisfaction as it relates to their working conditions. Current research indicates that professional development is a source that can contribute to satisfaction at work (Hoyt, 2012). However, the research…
ERIC Educational Resources Information Center
Vanthournout, Gert; Coertjens, Liesje; Gijbels, David; Donche, Vincent; Van Petegem, Peter
2013-01-01
Research regarding the development of students' learning approaches have at times reported unexpected or lack of expected changes. The current study explores the idea of differential developments in learning approaches according to students' initial learning profiles as a possible explanation for these outcomes. A learning profile is conceived as…
ERIC Educational Resources Information Center
Linder, Sandra M.; Rembert, Kellye; Simpson, Amber; Ramey, M. Deanna
2016-01-01
This multi-phase mixed-methods study explores provider and recipient perceptions of the current state of early childhood professional development in a southeastern area of the United States. Professional development for the early childhood workforce has been shown to positively influence the quality of early childhood classrooms. This study…
Dance Talent Development across the Lifespan: A Review of Current Research
ERIC Educational Resources Information Center
Chua, Joey
2014-01-01
The aim of this study is to compile and synthesize empirically based articles published between 2000 and 2012 about the critical issues of developing dance talents across the lifespan of children, adolescents and adults. The present article updates and extends a review article related to the identification and development in dance written by…
White Matter and Development in Children with an Autism Spectrum Disorder
ERIC Educational Resources Information Center
Mak-Fan, Kathleen M.; Morris, Drew; Vidal, Julie; Anagnostou, Evdokia; Roberts, Wendy; Taylor, Margot J.
2013-01-01
Recent research suggests that brain development follows an abnormal trajectory in children with autism spectrum disorders (ASD). The current study examined changes in diffusivity with age within defined white matter tracts in a group of typically developing children and a group of children with an ASD, aged 6 to 14 years. Age by group interactions…
Play and Practice in the Development of Sport-Specific Creativity in Team Ball Sports
ERIC Educational Resources Information Center
Memmert, Daniel; Baker, Joseph; Bertsch, Claudia
2010-01-01
Current theoretical approaches regarding the development of creativity support the view that gathering diversified experience over years is an ideal medium for creative thinking. This study examined the role of practice conditions in the development of creative behavior in team ball sports. Twelve trainers selected the most creative and the least…
ERIC Educational Resources Information Center
Bridgett, David J.; Laake, Lauren M.; Gartstein, Maria A.; Dorn, Danielle
2013-01-01
The current study examined the influence of maternal characteristics on the development of infant smiling and laughter, a marker of early positive emotionality (PE) and how maternal characteristics and the development of infant PE contributed to subsequent maternal parenting. One hundred fifty-nine mothers with 4-month-old infants participated.…
ERIC Educational Resources Information Center
Bruening, Jennifer E.; Dover, Kydani M.; Clark, Brianna S.
2009-01-01
Youth development research has found that children become more engaged and benefit more from being incorporated as decision makers. Thus participation helps promote development and encourages engagement. Based in theories of engagement and free-choice learning, the current research focused on a program combining sport/physical activity, life…
ERIC Educational Resources Information Center
Wang, Zhe; Soden, Brooke; Deater-Deckard, Kirby; Lukowski, Sarah L.; Schenker, Victoria J.; Willcutt, Erik G.; Thompson, Lee A.; Petrill, Stephen A.
2017-01-01
Socioeconomic risks (SES risks) are robust risk factors influencing children's academic development. However, it is unclear whether the effects of SES on academic development operate universally in all children equally or whether they vary differentially in children with particular characteristics. The current study aimed to explore children's…
"UNICERT," or: Towards the Development of a Unified Language Certificate for German Universities.
ERIC Educational Resources Information Center
Voss, Bernd
The standardization of second language proficiency levels for university students in Germany is discussed. Problems with the current system, in which each university has developed its own program of study and proficiency certification, are examined and a framework for development of a unified language certificate for all universities is outlined.…
ERIC Educational Resources Information Center
Fuller, Rhema D.; Percy, Vernon E.; Bruening, Jennifer E.; Cotrufo, Raymond J.
2013-01-01
Purpose: As there is little research that investigates the experiences of minority boys participating in youth development programs (Fashola, 2003), the current research focused on a sport-based youth development program for early adolescent Black and Latino boys in Hartford, CT. Specifically, the present study explored (a) what attracted minority…
ERIC Educational Resources Information Center
Bowman, Nicholas A.; Small, Jenny L.
2010-01-01
College student spiritual development constitutes an important, yet understudied topic in higher education research. In particular, very little is known about whether and how this development varies among students from diverse religious backgrounds. Using a longitudinal sample of 14,527 students from 136 institutions, the current study explored…
Developing a "Social Presence Scale" for E-Learning Environments
ERIC Educational Resources Information Center
Kilic Cakmak, Ebru; Cebi, Ayça; Kan, Adnan
2014-01-01
The purpose of the current study is to develop a "social presence scale" for e-learning environments. A systematic approach was followed for developing the scale. The scale was applied to 461 students registered in seven different programs at Gazi University. The sample was split into two subsamples on a random basis (n1 = 261; n2 =…
The Inception, Evolution, and Current State of the Moral Development School of Lawrence Kohlberg.
ERIC Educational Resources Information Center
Cortese, Anthony J.
Tiryakian's "school" approach is used to analyze the evolution of Kohlberg's study of moral development over the past 25 years. The first part of the paper contrasts the paradigm approach (Kuhn 1970) to the schools approach in defining the development of the social sciences. Specifically, Kuhn's definition of a paradigm…
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Gurney, Laura; Liyanage, Indika
2015-01-01
Under current Western neoliberal philosophy, promotion of efficiency and resolution of issues are typically expected to result from effective management. The education sector, too, has responded well to these expectations. Amongst such expectations, engagement in professional development activities (PDAs) by teachers of English as an additional…
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Boletin del Centro Nacional de Documentacion e Informacion Educativa, 1971
1971-01-01
This article discusses the education provisions established in the Argentine Plan for Development and Security (1971-1975). The statements on educational development call for a diagnostic study of the current cultural and educational situation, the establishment of objectives and strategies, goals for each level of education, steps for the…
STEM@1000mph: Developing Open Educational Resources in a Live Engineering Project
ERIC Educational Resources Information Center
Lanham, John; Howard, Yvonne; Drew, Ben; Johns, Dan
2013-01-01
Higher education institutions are recognising the clear benefits of open educational resources, and academics are engaging with the development of these resources. This paper presents a case study of OERs being developed using the live, current BloodhoundSSC world land speed record project as a basis. The paper outlines the rationale for the…
ERIC Educational Resources Information Center
Jeung, Chang-Wook; Yoon, Hea Jun; Park, Sunyoung; Jo, Sung Jun
2011-01-01
The primary purpose of the current study is to identify how human resource development (HRD) research has contributed to the knowledge base across social science disciplines during the past two decades. We identified the top 20 Academy of Human Resource Development (AHRD) journal articles that have been most frequently cited in research articles…
Glucocorticoids and adrenergic stimulation are both thought to control the development of adrenergic receptors/responses. n the current study, rats were exposed to dexamethasone or terbutaline during late gestation and the development of B-binding capabilities and adenylate cycla...
Concept Development in Learning Physics: The Case of Electric Current and Voltage Revisited
ERIC Educational Resources Information Center
Koponen, Ismo T.; Huttunen, Laura
2013-01-01
In learning conceptual knowledge in physics, a common problem is the development and differentiation of concepts in the learning process. An important part of this development process is the re-organisation or re-structuring process in which students' conceptual knowledge and concepts change. This study proposes a new view of concept…