Sample records for damage background estimated

  1. Oxidative DNA damage background estimated by a system model of base excision repair

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sokhansanj, B A; Wilson, III, D M

    Human DNA can be damaged by natural metabolism through free radical production. It has been suggested that the equilibrium between innate damage and cellular DNA repair results in an oxidative DNA damage background that potentially contributes to disease and aging. Efforts to quantitatively characterize the human oxidative DNA damage background level based on measuring 8-oxoguanine lesions as a biomarker have led to estimates varying over 3-4 orders of magnitude, depending on the method of measurement. We applied a previously developed and validated quantitative pathway model of human DNA base excision repair, integrating experimentally determined endogenous damage rates and model parametersmore » from multiple sources. Our estimates of at most 100 8-oxoguanine lesions per cell are consistent with the low end of data from biochemical and cell biology experiments, a result robust to model limitations and parameter variation. Our results show the power of quantitative system modeling to interpret composite experimental data and make biologically and physiologically relevant predictions for complex human DNA repair pathway mechanisms and capacity.« less

  2. Costs of IQ Loss from Leaded Aviation Gasoline Emissions

    PubMed Central

    Wolfe, Philip J.; Giang, Amanda; Ashok, Akshay; Selin, Noelle E.; Barrett, Steven R. H.

    2017-01-01

    In the United States, general aviation piston-driven aircraft are now the largest source of lead emitted to the atmosphere. Elevated lead concentrations impair children’s IQ and can lead to lower earnings potentials. This study is the first assessment of the nationwide annual costs of IQ losses from aircraft lead emissions. We develop a general aviation emissions inventory for the continental United States and model its impact on atmospheric concentrations using the Community Multi-Scale Air Quality Model (CMAQ). We use these concentrations to quantify the impacts of annual aviation lead emissions on the U.S. population using two methods: through static estimates of cohort-wide IQ deficits and through dynamic economy-wide effects using a computational general equilibrium model. We also examine the sensitivity of these damage estimates to different background lead concentrations, showing the impact of lead controls and regulations on marginal costs. We find that aircraft-attributable lead contributes to $1.06 billion 2006 USD ($0.01 – $11.6) in annual damages from lifetime earnings reductions, and that dynamic economy-wide methods result in damage estimates that are 54% larger. Because the marginal costs of lead are dependent on background concentration, the costs of piston-driven aircraft lead emissions are expected to increase over time as regulations on other emissions sources are tightened. PMID:27494542

  3. Costs of IQ Loss from Leaded Aviation Gasoline Emissions.

    PubMed

    Wolfe, Philip J; Giang, Amanda; Ashok, Akshay; Selin, Noelle E; Barrett, Steven R H

    2016-09-06

    In the United States, general aviation piston-driven aircraft are now the largest source of lead emitted to the atmosphere. Elevated lead concentrations impair children's IQ and can lead to lower earnings potentials. This study is the first assessment of the nationwide annual costs of IQ losses from aircraft lead emissions. We develop a general aviation emissions inventory for the continental United States and model its impact on atmospheric concentrations using the community multi-scale air quality model (CMAQ). We use these concentrations to quantify the impacts of annual aviation lead emissions on the U.S. population using two methods: through static estimates of cohort-wide IQ deficits and through dynamic economy-wide effects using a computational general equilibrium model. We also examine the sensitivity of these damage estimates to different background lead concentrations, showing the impact of lead controls and regulations on marginal costs. We find that aircraft-attributable lead contributes to $1.06 billion 2006 USD ($0.01-$11.6) in annual damages from lifetime earnings reductions, and that dynamic economy-wide methods result in damage estimates that are 54% larger. Because the marginal costs of lead are dependent on background concentration, the costs of piston-driven aircraft lead emissions are expected to increase over time as regulations on other emissions sources are tightened.

  4. Safety in the Chemical Laboratory.

    ERIC Educational Resources Information Center

    Gerlach, Rudolph

    1986-01-01

    Background information is provided on the registered trademark "TLV" (Threshold Limit Value), the term used to express tolerable concentrations. The TLV of a compound is an estimate extrapolated from some defined damage to humans or animals at higher concentrations or by drawing analogies between similar concentrations. (JN)

  5. Large-scale application of the flood damage model RAilway Infrastructure Loss (RAIL)

    NASA Astrophysics Data System (ADS)

    Kellermann, Patric; Schönberger, Christine; Thieken, Annegret H.

    2016-11-01

    Experience has shown that river floods can significantly hamper the reliability of railway networks and cause extensive structural damage and disruption. As a result, the national railway operator in Austria had to cope with financial losses of more than EUR 100 million due to flooding in recent years. Comprehensive information on potential flood risk hot spots as well as on expected flood damage in Austria is therefore needed for strategic flood risk management. In view of this, the flood damage model RAIL (RAilway Infrastructure Loss) was applied to estimate (1) the expected structural flood damage and (2) the resulting repair costs of railway infrastructure due to a 30-, 100- and 300-year flood in the Austrian Mur River catchment. The results were then used to calculate the expected annual damage of the railway subnetwork and subsequently analysed in terms of their sensitivity to key model assumptions. Additionally, the impact of risk aversion on the estimates was investigated, and the overall results were briefly discussed against the background of climate change and possibly resulting changes in flood risk. The findings indicate that the RAIL model is capable of supporting decision-making in risk management by providing comprehensive risk information on the catchment level. It is furthermore demonstrated that an increased risk aversion of the railway operator has a marked influence on flood damage estimates for the study area and, hence, should be considered with regard to the development of risk management strategies.

  6. Evaluating the Human Damage of Tsunami at Each Time Frame in Aggregate Units Based on GPS data

    NASA Astrophysics Data System (ADS)

    Ogawa, Y.; Akiyama, Y.; Kanasugi, H.; Shibasaki, R.; Kaneda, H.

    2016-06-01

    Assessments of the human damage caused by the tsunami are required in order to consider disaster prevention at such a regional level. Hence, there is an increasing need for the assessments of human damage caused by earthquakes. However, damage assessments in japan currently usually rely on static population distribution data, such as statistical night time population data obtained from national census surveys. Therefore, human damage estimation that take into consideration time frames have not been assessed yet. With these backgrounds, the objectives of this study are: to develop a method for estimating the population distribution of the for each time frame, based on location positioning data observed with mass GPS loggers of mobile phones, to use a evacuation and casualties models for evaluating human damage due to the tsunami, and evaluate each time frame by using the data developed in the first objective, and 3) to discuss the factors which cause the differences in human damage for each time frame. By visualizing the results, we clarified the differences in damage depending on time frame, day and area. As this study enables us to assess damage for any time frame in and high resolution, it will be useful to consider provision for various situations when an earthquake may hit, such as during commuting hours or working hours and week day or holiday.

  7. An integrated physiology model to study regional lung damage effects and the physiologic response

    PubMed Central

    2014-01-01

    Background This work expands upon a previously developed exercise dynamic physiology model (DPM) with the addition of an anatomic pulmonary system in order to quantify the impact of lung damage on oxygen transport and physical performance decrement. Methods A pulmonary model is derived with an anatomic structure based on morphometric measurements, accounting for heterogeneous ventilation and perfusion observed experimentally. The model is incorporated into an existing exercise physiology model; the combined system is validated using human exercise data. Pulmonary damage from blast, blunt trauma, and chemical injury is quantified in the model based on lung fluid infiltration (edema) which reduces oxygen delivery to the blood. The pulmonary damage component is derived and calibrated based on published animal experiments; scaling laws are used to predict the human response to lung injury in terms of physical performance decrement. Results The augmented dynamic physiology model (DPM) accurately predicted the human response to hypoxia, altitude, and exercise observed experimentally. The pulmonary damage parameters (shunt and diffusing capacity reduction) were fit to experimental animal data obtained in blast, blunt trauma, and chemical damage studies which link lung damage to lung weight change; the model is able to predict the reduced oxygen delivery in damage conditions. The model accurately estimates physical performance reduction with pulmonary damage. Conclusions We have developed a physiologically-based mathematical model to predict performance decrement endpoints in the presence of thoracic damage; simulations can be extended to estimate human performance and escape in extreme situations. PMID:25044032

  8. FASD Prevalence among Schoolchildren in Poland

    ERIC Educational Resources Information Center

    Okulicz-Kozaryn, Katarzyna; Borkowska, Magdalena; Brzózka, Krzysztof

    2017-01-01

    Background: Prenatal Alcohol Exposure is a major cause of brain damage and developmental delay, known as Fetal Alcohol Spectrum Disorders (FASD) but in Poland is rarely diagnosed and the scale of problem is not known. Methods: An active case ascertainment approach was applied to estimate the prevalence of FASD among 7-9 years olds. Pre-screening…

  9. Detection the nonlinear ultrasonic signals based on modified Duffing equations

    NASA Astrophysics Data System (ADS)

    Zhang, Yuhua; Mao, Hanling; Mao, Hanying; Huang, Zhenfeng

    The nonlinear ultrasonic signals, like second harmonic generation (SHG) signals, could reflect the nonlinearity of material induced by fatigue damage in nonlinear ultrasonic technique which are weak nonlinear signals and usually submerged by strong background noise. In this paper the modified Duffing equations are applied to detect the SHG signals relating to the fatigue damage of material. Due to the Duffing equation could only detect the signal with specific frequency and initial phase, firstly the frequency transformation is carried on the Duffing equation which could detect the signal with any frequency. Then the influence of initial phases of to-be-detected signal and reference signal on the detection result is studied in detail, four modified Duffing equations are proposed to detect actual engineering signals with any initial phase. The relationship between the response amplitude and the total driving force is applied to estimate the amplitude of weak periodic signal. The detection results show the modified Duffing equations could effectively detect the second harmonic in SHG signals. When the SHG signals include strong background noise, the noise doesn't change the motion state of Duffing equation and the second harmonic signal could be detected until the SNR of noisy SHG signals are -26.3, yet the frequency spectrum method could only identify when the SNR is greater than 0.5. When estimation the amplitude of second harmonic signal, the estimation error of Duffing equation is obviously less than the frequency spectrum analysis method under the same noise level, which illustrates the Duffing equation has the noise immune capacity. The presence of the second harmonic signal in nonlinear ultrasonic experiments could provide an insight about the early fatigue damage of engineering components.

  10. Assessing the Social and Environmental Costs of Institutional ...

    EPA Pesticide Factsheets

    Background/Question/Methods: Release of N to air, land and water has a host of effects on human health, ecosystems and the economy, many of which scientists and economists are just beginning to develop methods to quantify. In order to understand the broader connections to sustainability, more effort is needed to connect N release to the environment with the impacts on social and economic systems. We estimate the damage costs associated with the institutional nitrogen (N) footprint and explore how this information could be used to create more sustainable institutions. Potential damages associated with the release of NOx and N2O to air and release of N to water were estimated using a cost per unit N approach. Results/Conclusions: Annual potential damage costs to human health, agriculture and natural ecosystems associated with the N footprint of institutions were $10.5 million USD (2014) at the University of Virginia (UVA) and $3.0 million USD at the University of New Hampshire (UNH). Costs associated with the release of nitrogen oxides (NOx) to human health, in particular the use of coal-derived energy, were the largest component of damage at UVA. At UNH the energy N footprint is much lower because of a co-generation source, and thus the majority of damages were associated with food production. Annual damages associated with release of N from food production were very similar at the two universities ($1.37 vs. $1.66 million at UVA and UNH respectively). T

  11. Estimation of the Characterized Tsunami Source Model considering the Complicated Shape of Tsunami Source by Using the observed waveforms of GPS Buoys in the Nankai Trough

    NASA Astrophysics Data System (ADS)

    Seto, S.; Takahashi, T.

    2017-12-01

    In the 2011 Tohoku earthquake tsunami disaster, the delay of understanding damage situation increased the human damage. To solve this problem, it is important to search the severe damaged areas. The tsunami numerical modeling is useful to estimate damages and the accuracy of simulation depends on the tsunami source. Seto and Takahashi (2017) proposed a method to estimate the characterized tsunami source model by using the limited observed data of GPS buoys. The model consists of Large slip zone (LSZ), Super large slip zone (SLSZ) and background rupture zone (BZ) as the Cabinet Office, Government of Japan (below COGJ) reported after the Tohoku tsunami. At the beginning of this method, the rectangular fault model is assumed based on the seismic magnitude and hypocenter reported right after an earthquake. By using the fault model, tsunami propagation is simulated numerically, and the fault model is improved after comparing the computed data with the observed data repeatedly. In the comparison, correlation coefficient and regression coefficient are used as indexes. They are calculated with the observed and the computed tsunami wave profiles. This repetition is conducted to get the two coefficients close to 1.0, which makes the precise of the fault model higher. However, it was indicated as the improvement that the model did not examine a complicated shape of tsunami source. In this study, we proposed an improved model to examine the complicated shape. COGJ(2012) assumed that possible tsunami source region in the Nankai trough consisted of the several thousands small faults. And, we use these small faults to estimate the targeted tsunami source in this model. Therefore, we can estimate the complicated tsunami source by using these small faults. The estimation of BZ is carried out as a first step, and LSZ and SLSZ are estimated next as same as the previous model. The proposed model by using GPS buoy was applied for a tsunami scenario in the Nankai Trough. As a result, the final estimated location of LSZ and SLSZ in BZ are estimated well.

  12. Estimation of rice yield affected by drought and relation between rice yield and TVDI

    NASA Astrophysics Data System (ADS)

    Hongo, C.; Tamura, E.; Sigit, G.

    2016-12-01

    Impact of climate change is not only seen on food production but also on food security and sustainable development of society. Adaptation to climate change is a pressing issue throughout the world to reduce the risks along with the plans and strategies for food security and sustainable development. As a key adaptation to the climate change, agricultural insurance is expected to play an important role in stabilizing agricultural production through compensating the losses caused by the climate change. As the adaptation, the Government of Indonesia has launched agricultural insurance program for damage of rice by drought, flood and pest and disease. The Government started a pilot project in 2013 and this year the pilot project has been extended to 22 provinces. Having the above as background, we conducted research on development of new damage assessment method for rice using remote sensing data which could be used for evaluation of damage ratio caused by drought in West Java, Indonesia. For assessment of the damage ratio, estimation of rice yield is a key. As the result of our study, rice yield affected by drought in dry season could be estimated at level of 1 % significance using SPOT 7 data taken in 2015, and the validation result was 0.8t/ha. Then, the decrease ratio in rice yield about each individual paddy field was calculated using data of the estimated result and the average yield of the past 10 years. In addition, TVDI (Temperature Vegetation Dryness Index) which was calculated from Landsat8 data in heading season indicated the dryness in low yield area. The result suggests that rice yield was affected by irrigation water shortage around heading season as a result of the decreased precipitation by El Nino. Through our study, it becomes clear that the utilization of remote sensing data can be promising for assessment of the damage ratio of rice production precisely, quickly and quantitatively, and also it can be incorporated into the insurance procedures.

  13. Uncertainty in flood damage estimates and its potential effect on investment decisions

    NASA Astrophysics Data System (ADS)

    Wagenaar, D. J.; de Bruijn, K. M.; Bouwer, L. M.; de Moel, H.

    2016-01-01

    This paper addresses the large differences that are found between damage estimates of different flood damage models. It explains how implicit assumptions in flood damage functions and maximum damages can have large effects on flood damage estimates. This explanation is then used to quantify the uncertainty in the damage estimates with a Monte Carlo analysis. The Monte Carlo analysis uses a damage function library with 272 functions from seven different flood damage models. The paper shows that the resulting uncertainties in estimated damages are in the order of magnitude of a factor of 2 to 5. The uncertainty is typically larger for flood events with small water depths and for smaller flood events. The implications of the uncertainty in damage estimates for flood risk management are illustrated by a case study in which the economic optimal investment strategy for a dike segment in the Netherlands is determined. The case study shows that the uncertainty in flood damage estimates can lead to significant over- or under-investments.

  14. Improving Flood Damage Assessment Models in Italy

    NASA Astrophysics Data System (ADS)

    Amadio, M.; Mysiak, J.; Carrera, L.; Koks, E.

    2015-12-01

    The use of Stage-Damage Curve (SDC) models is prevalent in ex-ante assessments of flood risk. To assess the potential damage of a flood event, SDCs describe a relation between water depth and the associated potential economic damage over land use. This relation is normally developed and calibrated through site-specific analysis based on ex-post damage observations. In some cases (e.g. Italy) SDCs are transferred from other countries, undermining the accuracy and reliability of simulation results. Against this background, we developed a refined SDC model for Northern Italy, underpinned by damage compensation records from a recent flood event. Our analysis considers both damage to physical assets and production losses from business interruptions. While the first is calculated based on land use information, production losses are measured through the spatial distribution of Gross Value Added (GVA). An additional component of the model assesses crop-specific agricultural losses as a function of flood seasonality. Our results show an overestimation of asset damage from non-calibrated SDC values up to a factor of 4.5 for tested land use categories. Furthermore, we estimate that production losses amount to around 6 per cent of the annual GVA. Also, maximum yield losses are less than a half of the amount predicted by the standard SDC methods.

  15. Development of an Advanced Aidman Vision Screener (AVS) for selective assessment of outer and inner laser induced retinal injury

    NASA Astrophysics Data System (ADS)

    Boye, Michael W.; Zwick, Harry; Stuck, Bruce E.; Edsall, Peter R.; Akers, Andre

    2007-02-01

    The need for tools that can assist in evaluating visual function is an essential and a growing requirement as lasers on the modern battlefield mature and proliferate. The requirement for rapid and sensitive vision assessment under field conditions produced the USAMRD Aidman Vision Screener (AVS), designed to be used as a field diagnostic tool for assessing laser induced retinal damage. In this paper, we describe additions to the AVS designed to provide a more sensitive assessment of laser induced retinal dysfunction. The AVS incorporates spectral LogMar Acuity targets without and with neural opponent chromatic backgrounds. Thus, it provides the capability of detecting selective photoreceptor damage and its functional consequences at the level of both the outer and inner retina. Modifications to the original achromatic AVS have been implemented to detect selective cone system dysfunction by providing LogMar acuity Landolt rings associated with the peak spectral absorption regions of the S (short), M (middle), and L (long) wavelength cone photoreceptor systems. Evaluation of inner retinal dysfunction associated with selective outer cone damage employs LogMar spectral acuity charts with backgrounds that are neurally opponent. Thus, the AVS provides the capability to assess the effect of selective cone dysfunction on the normal neural balance at the level of the inner retinal interactions. Test and opponent background spectra have been optimized by using color space metrics. A minimal number of three AVS evaluations will be utilized to provide an estimate of false alarm level.

  16. A Rapid Public Health Needs Assessment Framework for after Major Earthquakes Using High-Resolution Satellite Imagery.

    PubMed

    Zhao, Jian; Ding, Fan; Wang, Zhe; Ren, Jinghuan; Zhao, Jing; Wang, Yeping; Tang, Xuefeng; Wang, Yong; Yao, Jianyi; Li, Qun

    2018-05-30

    Background : Earthquakes causing significant damage have occurred frequently in China, producing enormous health losses, damage to the environment and public health issues. Timely public health response is crucial to reduce mortality and morbidity and promote overall effectiveness of rescue efforts after a major earthquake. Methods : A rapid assessment framework was established based on GIS technology and high-resolution remote sensing images. A two-step casualties and injures estimation method was developed to evaluate health loss with great rapidity. Historical data and health resources information was reviewed to evaluate the damage condition of medical resources and public health issues. Results : The casualties and injures are estimated within a few hours after an earthquake. For the Wenchuan earthquake, which killed about 96,000 people and injured about 288,000, the estimation accuracy is about 77%. 242/294 (82.3%) of the medical existing institutions were severely damaged. About 40,000 tons of safe drinking water was needed every day to ensure basic living needs. The risk of water-borne and foodborne disease, respiratory and close contact transmission disease is high. For natural foci diseases, the high-risk area of schistosomiasis was mapped in Lushan County as an example. Finally, temporary settlements for victims of earthquake were mapped. Conclusions : High resolution Earth observation technology can provide a scientific basis for public health emergency management in the major disasters field, which will be of great significance in helping policy makers effectively improve health service ability and public health emergency management in prevention and control of infectious diseases and risk assessment.

  17. The Air Quality and Economic Impact of Atmospheric Lead from General Aviation Aircraft in the United States

    NASA Astrophysics Data System (ADS)

    Wolfe, P. J.; Selin, N. E.; Barrett, S. R. H.

    2015-12-01

    While leaded fuels for automobiles were phased-out of use in the United States by 1996, lead (Pb) continues to be used as an anti-knock additive for piston-driven aircraft. We model the annual concentration of atmospheric lead attributable to piston driven aircraft emissions in the continental United States using the Community Multi-scale Air Quality (CMAQ) model. Using aircraft emissions inventories for 2008, we then calculate annual economic damages from lead as lifetime employment losses for a one-year cohort exposed to elevated atmospheric lead concentrations using a range of concentration response functions from literature. Mean and median estimates of annual damages attributable to lifetime lost earnings are 1.06 and 0.60 billion respectively. Economy-wide impacts of IQ-deficits on productivity and labor increase expected damages by 54%. Damages are sensitive to background lead concentrations; as emissions decrease from other sources, the damages attributable to aviation are expected to increase holding aviation emissions constant. The monetary impact of General Aviation lead emissions on the environment is the same order of magnitude as noise, climate change, and air quality degradation from all commercial operations.

  18. Uncertainty in flood damage estimates and its potential effect on investment decisions

    NASA Astrophysics Data System (ADS)

    Wagenaar, Dennis; de Bruijn, Karin; Bouwer, Laurens; de Moel, Hans

    2015-04-01

    This paper addresses the large differences that are found between damage estimates of different flood damage models. It explains how implicit assumptions in flood damage models can lead to large uncertainties in flood damage estimates. This explanation is used to quantify this uncertainty with a Monte Carlo Analysis. This Monte Carlo analysis uses a damage function library with 272 functions from 7 different flood damage models. This results in uncertainties in the order of magnitude of a factor 2 to 5. This uncertainty is typically larger for small water depths and for smaller flood events. The implications of the uncertainty in damage estimates for flood risk management are illustrated by a case study in which the economic optimal investment strategy for a dike segment in the Netherlands is determined. The case study shows that the uncertainty in flood damage estimates can lead to significant over- or under-investments.

  19. Uncertainty in flood damage estimates and its potential effect on investment decisions

    NASA Astrophysics Data System (ADS)

    Wagenaar, D. J.; de Bruijn, K. M.; Bouwer, L. M.; De Moel, H.

    2015-01-01

    This paper addresses the large differences that are found between damage estimates of different flood damage models. It explains how implicit assumptions in flood damage models can lead to large uncertainties in flood damage estimates. This explanation is used to quantify this uncertainty with a Monte Carlo Analysis. As input the Monte Carlo analysis uses a damage function library with 272 functions from 7 different flood damage models. This results in uncertainties in the order of magnitude of a factor 2 to 5. The resulting uncertainty is typically larger for small water depths and for smaller flood events. The implications of the uncertainty in damage estimates for flood risk management are illustrated by a case study in which the economic optimal investment strategy for a dike segment in the Netherlands is determined. The case study shows that the uncertainty in flood damage estimates can lead to significant over- or under-investments.

  20. Design of overload vehicle monitoring and response system based on DSP

    NASA Astrophysics Data System (ADS)

    Yu, Yan; Liu, Yiheng; Zhao, Xuefeng

    2014-03-01

    The overload vehicles are making much more damage to the road surface than the regular ones. Many roads and bridges are equipped with structural health monitoring system (SHM) to provide early-warning to these damage and evaluate the safety of road and bridge. However, because of the complex nature of SHM system, it's expensive to manufacture, difficult to install and not well-suited for the regular bridges and roads. Based on this application background, this paper designs a compact structural health monitoring system based on DSP, which is highly integrated, low-power, easy to install and inexpensive to manufacture. The designed system is made up of sensor arrays, the charge amplifier module, the DSP processing unit, the alarm system for overload, and the estimate for damage of the road and bridge structure. The signals coming from sensor arrays go through the charge amplifier. DSP processing unit will receive the amplified signals, estimate whether it is an overload signal or not, and convert analog variables into digital ones so that they are compatible with the back-end digital circuit for further processing. The system will also restrict certain vehicles that are overweight, by taking image of the car brand, sending the alarm, and transferring the collected pressure data to remote data center for further monitoring analysis by rain-flow counting method.

  1. Method of recognizing the high-speed railway noise barriers based on the distance image

    NASA Astrophysics Data System (ADS)

    Ma, Le; Shao, Shuangyun; Feng, Qibo; Liu, Bingqian; Kim, Chol Ryong

    2016-10-01

    The damage or lack of the noise barriers is one of the important hidden troubles endangering the safety of high-speed railway. In order to obtain the vibration information of the noise barriers, the online detection systems based on laser vision were proposed. The systems capture images of the laser stripe on the noise barriers and export data files containing distance information between the detection systems on the train and the noise barriers. The vibration status or damage of the noise barriers can be estimated depending on the distance information. In this paper, we focused on the method of separating the area of noise barrier from the background automatically. The test results showed that the proposed method is in good efficiency and accuracy.

  2. Distributed Damage Estimation for Prognostics based on Structural Model Decomposition

    NASA Technical Reports Server (NTRS)

    Daigle, Matthew; Bregon, Anibal; Roychoudhury, Indranil

    2011-01-01

    Model-based prognostics approaches capture system knowledge in the form of physics-based models of components, and how they fail. These methods consist of a damage estimation phase, in which the health state of a component is estimated, and a prediction phase, in which the health state is projected forward in time to determine end of life. However, the damage estimation problem is often multi-dimensional and computationally intensive. We propose a model decomposition approach adapted from the diagnosis community, called possible conflicts, in order to both improve the computational efficiency of damage estimation, and formulate a damage estimation approach that is inherently distributed. Local state estimates are combined into a global state estimate from which prediction is performed. Using a centrifugal pump as a case study, we perform a number of simulation-based experiments to demonstrate the approach.

  3. Adaptive measurement selection for progressive damage estimation

    NASA Astrophysics Data System (ADS)

    Zhou, Wenfan; Kovvali, Narayan; Papandreou-Suppappola, Antonia; Chattopadhyay, Aditi; Peralta, Pedro

    2011-04-01

    Noise and interference in sensor measurements degrade the quality of data and have a negative impact on the performance of structural damage diagnosis systems. In this paper, a novel adaptive measurement screening approach is presented to automatically select the most informative measurements and use them intelligently for structural damage estimation. The method is implemented efficiently in a sequential Monte Carlo (SMC) setting using particle filtering. The noise suppression and improved damage estimation capability of the proposed method is demonstrated by an application to the problem of estimating progressive fatigue damage in an aluminum compact-tension (CT) sample using noisy PZT sensor measurements.

  4. Shrinkage and growth compensation in common sunflowers: refining estimates of damage

    USGS Publications Warehouse

    Sedgwick, James A.; Oldemeye, John L.; Swenson, Elizabeth L.

    1986-01-01

    Shrinkage and growth compensation of artificially damaged common sunflowers (Helianthus annuus) were studied in central North Dakota during 1981-1982 in an effort to increase accuracy of estimates of blackbird damage to sunflowers. In both years, as plants matured damaged areas on seedheads shrank at a greater rate than the sunflower heads themselves. This differential shrinkage resulted in an underestimation of the area damaged. Sunflower head and damaged-area shrinkage varied widely by time and degree of damage and by size of the seedhead damaged. Because variation in shrinkage by time of damage was so large, predicting when blackbird damage occurs may be the most important factor in estimating seed loss. Yield'occupied seed area was greater (P < 0.05) for damaged than undamaged heads and tended to increase as degree of damage inflicted increased, indicating growth compensation was occurring in response to lost seeds. Yields of undamaged seeds in seedheads damaged during early seed development were higher than those of heads damaged later. This suggested that there was a period of maximal response to damage when plants were best able to redirect growth to seeds remaining in the head. Sunflowers appear to be able to compensate for damage of ≤ 15% of the total hear area. Estimates of damage can be improved by applying empirical results of differential shrinkage and growth compensations.

  5. Damage severity estimation from the global stiffness decrease

    NASA Astrophysics Data System (ADS)

    Nitescu, C.; Gillich, G. R.; Abdel Wahab, M.; Manescu, T.; Korka, Z. I.

    2017-05-01

    In actual damage detection methods, localization and severity estimation can be treated separately. The severity is commonly estimated using fracture mechanics approach, with the main disadvantage of involving empirically deduced relations. In this paper, a damage severity estimator based on the global stiffness reduction is proposed. This feature is computed from the deflections of the intact and damaged beam, respectively. The damage is always located where the bending moment achieves maxima. If the damage is positioned elsewhere on the beam, its effect becomes lower, because the stress is produced by a diminished bending moment. It is shown that the global stiffness reduction produced by a crack is the same for all beams with a similar cross-section, regardless of the boundary conditions. One mathematical relation indicating the severity and another indicating the effect of removing damage from the beam. Measurements on damaged beams with different boundary conditions and cross-sections are carried out, and the location and severity are found using the proposed relations. These comparisons prove that the proposed approach can be used to accurately compute the severity estimator.

  6. Inflight proton activation and damage on a CdTe detection plane

    NASA Astrophysics Data System (ADS)

    Simões, N.; Maia, J. M.; Curado da Silva, R. M.; Ghithan, S.; Crespo, P.; do Carmo, S. J. C.; Alves, Francisco; Moita, M.; Auricchio, N.; Caroli, E.

    2018-01-01

    Future high-energy space telescope missions require further analysis of orbital environment induced activation and radiation damage on main instruments. A scientific satellite is exposed to the charged particles harsh environment, mainly geomagnetically trapped protons (up to ∼300 MeV) that interact with the payload materials, generating nuclear activation background noise within instruments' operational energy range and causing radiation damage in detector material. As a consequence, instruments' performances deteriorate during the mission time-frame. In order to optimize inflight operational performances of future CdTe high-energy telescope detection planes under orbital radiation environment, we measured and analyzed the effects generated by protons on CdTe ACRORAD detectors with 2.56 cm2 sensitive area and 2 mm thickness. To carry-out this study, several sets of measurements were performed under a ∼14 MeV cyclotron proton beam. Nuclear activation radionuclides' identification was performed. Estimation of activation background generated by short-lived radioisotopes during one day was less than ∼1.3 ×10-5 counts cm-2 s-1 keV-1 up to 800 keV. A noticeable gamma-rays energy resolution degradation was registered (∼60% @ 122 keV, ∼14% @ 511 and ∼2.2% @ 1275 keV) after an accumulated proton fluence of 4.5 ×1010 protons cm-2, equivalent to ∼22 years in-orbit fluence. One year later, the energy resolution of the irradiated prototype showed a good level of performancerecovery.

  7. Estimating the welfare loss to households from natural disasters in developing countries: a contingent valuation study of flooding in Vietnam

    PubMed Central

    Navrud, Ståle; Tuan, Tran Huu; Tinh, Bui Duc

    2012-01-01

    Background Natural disasters have severe impacts on the health and well-being of affected households. However, we find evidence that official damage cost assessments for floods and other natural disasters in Vietnam, where households have little or no insurance, clearly underestimate the total economic damage costs of these events as they do not include the welfare loss from mortality, morbidity and well-being experienced by the households affected by the floods. This should send a message to the local communities and national authorities that higher investments in flood alleviation, reduction and adaptive measures can be justified since the social benefits of these measures in terms of avoided damage costs are higher than previously thought. Methods We pioneer the use of the contingent valuation (CV) approach of willingness-to-contribute (WTC) labour to a flood prevention program, as a measure of the welfare loss experienced by household due to a flooding event. In a face-to-face household survey of 706 households in the Quang Nam province in Central Vietnam, we applied this approach together with reported direct physical damage in order to shed light of the welfare loss experienced by the households. We asked about households’ WTC labour and multiplied their WTC person-days of labour by an estimate for their opportunity cost of time in order to estimate the welfare loss to households from the 2007 floods. Results The results showed that this contingent valuation (CV) approach of asking about willingness-to-pay in-kind avoided the main problems associated with applying CV in developing countries. Conclusion Thus, the CV approach of WTC labour instead of money is promising in terms of capturing the total welfare loss of natural disasters, and promising in terms of further application in other developing countries and for other types of natural disasters. PMID:22761603

  8. Probabilistic Methodology for Estimation of Number and Economic Loss (Cost) of Future Landslides in the San Francisco Bay Region, California

    USGS Publications Warehouse

    Crovelli, Robert A.; Coe, Jeffrey A.

    2008-01-01

    The Probabilistic Landslide Assessment Cost Estimation System (PLACES) presented in this report estimates the number and economic loss (cost) of landslides during a specified future time in individual areas, and then calculates the sum of those estimates. The analytic probabilistic methodology is based upon conditional probability theory and laws of expectation and variance. The probabilistic methodology is expressed in the form of a Microsoft Excel computer spreadsheet program. Using historical records, the PLACES spreadsheet is used to estimate the number of future damaging landslides and total damage, as economic loss, from future landslides caused by rainstorms in 10 counties of the San Francisco Bay region in California. Estimates are made for any future 5-year period of time. The estimated total number of future damaging landslides for the entire 10-county region during any future 5-year period of time is about 330. Santa Cruz County has the highest estimated number of damaging landslides (about 90), whereas Napa, San Francisco, and Solano Counties have the lowest estimated number of damaging landslides (5?6 each). Estimated direct costs from future damaging landslides for the entire 10-county region for any future 5-year period are about US $76 million (year 2000 dollars). San Mateo County has the highest estimated costs ($16.62 million), and Solano County has the lowest estimated costs (about $0.90 million). Estimated direct costs are also subdivided into public and private costs.

  9. An assessment of the doses received by members of the public in Japan following the nuclear accident at Fukushima Daiichi nuclear power plant.

    PubMed

    Bedwell, P; Mortimer, K; Wellings, J; Sherwood, J; Leadbetter, S J; Haywood, S M; Charnock, T; Jones, A R; Hort, M C

    2015-12-01

    The earthquake and tsunami on 11 March 2011, centred off the east coast of Japan, caused considerable destruction and substantial loss of life along large swathes of the Japanese coastline. The tsunami damaged the Fukushima Daiichi nuclear power plant (NPP), resulting in prolonged releases of radioactive material into the environment. This paper assesses the doses received by members of the public in Japan. The assessment is based on an estimated source term and atmospheric dispersion modelling rather than monitoring data. It is evident from this assessment that across the majority of Japan the estimates of dose are very low, for example they are estimated to be less than the annual average dose from natural background radiation in Japan. Even in the regions local to Fukushima Daiichi NPP (and not affected by any form of evacuation) the maximum lifetime effective dose is estimated to be well below the cumulative natural background dose over the same period. The impact of the urgent countermeasures on the estimates of dose was considered. And the relative contribution to dose from the range of exposure pathways and radionuclides were evaluated. Analysis of estimated doses focused on the geographic irregularity and the impact of the meteorological conditions. For example the dose to an infant's thyroid received over the first year was estimated to be greater in Hirono than in the non-evacuated region of Naraha, despite Hirono being further from the release location. A number of factors were identified and thought to contribute towards this outcome, including the local wind pattern which resulted in the recirculation of part of the release. The non-uniform nature of dose estimates strengthens the case for evaluations based on dispersion modelling.

  10. The Estimation Modelling of Damaged Areas by Harmful Animals

    NASA Astrophysics Data System (ADS)

    Jang, R.; Sung, M.; Hwang, J.; Jeon, S. W.

    2017-12-01

    The Republic of Korea has undergone rapid development and urban development without sufficient consideration of the environment. This type of growth is accompanied by a reduction in forest area and wildlife habitat. It is a phenomenon that affects the habitat of large mammals more than small. Especially in Korea, the damage caused by wild boar(Sus scrofa) is harsher than other large mammalian species like water deer(Hydropotes inermis), which also means that the number of these reported cases of this species is higher than ones of other mammals. Wild boar has three to eight cubs per year and it is possible to breed every year, which makes it more populous comparing with the fragmented habitats. It could be regarded as one of the top predators in Korea, which it is inevitable for humans to intervene this creature in population control. In addition, some individuals have been forced to be retreated from other habitats in major habitats, or to invade human activity areas for food activity, thereby destroying crops. Ultimately, this mammal species has been treated as farm pest animals through committing road kills and urban emergences. In this study, we has estimated possible farm pest animal present points from the damage district using 2,505 hazardous wildlife damage areas with four types of geological informations, four kinds of forest information, land cover, and distribution of farmland occurred in Gyeongnam province in Korea. In the estimating model, utilizing MAXENT, information of background point was set to 10,000, 70% of the damaged sites were used to construct the model, 30% was used for verification, and 10 times of crossvalidate were proceeded - verified by AUC of ROC. As a result of analyses, AUC was 0.847, and the percent contribution of the forest information was the distance toward inner-forest areas, 36.1%, the land cover, 16.5%, the distance from the field, 14.9%. Furthermore, the permutation importance was 24.9% of the cover, 12.3% of the height, and 11.9% of the slope. The results indicate that the areas with high damage predictions were highly cultivated in valleys adjacent to the forests. This can be interpreted as a result of reflecting the characteristics of feeding on the farmland where the wild boar, which has forests as its main habitat, can access relatively easily and obtain good quality food.

  11. Benefits of invasion prevention: Effect of time lags, spread rates, and damage persistence

    Treesearch

    Rebecca S. Epanchin-Niell; Andrew M. Liebhold

    2015-01-01

    Quantifying economic damages caused by invasive species is crucial for cost-benefit analyses of biosecurity measures. Most studies focus on short-term damage estimates, but evaluating exclusion or prevention measures requires estimates of total anticipated damages from the time of establishment onward. The magnitude of such damages critically depends on the timing of...

  12. Study of the Seismic Cycle of large Earthquakes in central Peru: Lima Region

    NASA Astrophysics Data System (ADS)

    Norabuena, E. O.; Quiroz, W.; Dixon, T. H.

    2009-12-01

    Since historical times, the Peruvian subduction zone has been source of large and destructive earthquakes. The more damaging one occurred on May 30 1970 offshore Peru’s northern city of Chimbote with a death toll of 70,000 people and several hundred US million dollars in property damage. More recently, three contiguous plate interface segments in southern Peru completed their seismic cycle generating the 1996 Nazca (Mw 7.1), the 2001 Atico-Arequipa (Mw 8.4) and the 2007 Pisco (Mw 7.9) earthquakes. GPS measurements obtained between 1994-2001 by IGP-CIW an University of Miami-RSMAS on the central Andes of Peru and Bolivia were used to estimate their coseismic displacements and late stage of interseismic strain accumulation. However, we focus our interest in central Peru-Lima region, which with its about 9’000,000 inhabitants is located over a locked plate interface that has not broken with magnitude Mw 8 earthquakes since May 1940, September 1966 and October 1974. We use a network of 11 GPS monuments to estimate the interseismic velocity field, infer spatial variations of interplate coupling and its relation with the background seismicity of the region.

  13. Efficacy and safety of damage control in experimental animal models of injury: protocol for a systematic review and meta-analysis

    PubMed Central

    2014-01-01

    Background Although abbreviated surgery with planned reoperation (damage control surgery) is now widely used to manage major trauma patients, the procedure and its component interventions have not been evaluated in randomized controlled trials (RCTs). While some have suggested the need for such trials, they are unlikely to be conducted because of patient safety concerns. As animal studies may overcome several of the limitations of existing observational damage control studies, the primary objective of this study is to evaluate the efficacy and safety of damage control versus definitive surgery in experimental animal models of injury. Methods/design We will search electronic databases (Medline, Embase, PubMed, Web of Science, Scopus, and the Cochrane Library), conference abstracts, personal files, and bibliographies of included articles. We will include RCTs and prospective cohort studies that utilized an animal model of injury and compared damage control surgery (or specific damage control interventions or adjuncts) to definitive surgery (or specific definitive surgical interventions). Two investigators will independently evaluate the internal and external/construct validity of individual studies. The primary outcome will be all-cause mortality. Secondary outcomes will include blood loss amounts; blood pressures and heart rates; urinary outputs; core body temperatures; arterial lactate, pH, and base deficit/excess values; prothrombin and partial thromboplastin times; international normalized ratios; and thromboelastography (TEG) results/activated clotting times. We will calculate summary relative risks (RRs) of mortality and mean differences (for continuous outcomes) using DerSimonian and Laird random effects models. Heterogeneity will be explored using subgroup meta-analysis and meta-regression. We will assess for publication bias using funnel plots and Begg’s and Egger’s tests. When evidence of publication bias exists, we will use the Duval and Tweedie trim and fill method to estimate the potential influence of this bias on pooled summary estimates. Discussion This study will evaluate the efficacy and safety of damage control in experimental animal models of injury. Study results will be used to guide future clinical evaluations of damage control surgery, determine which animal study outcomes may potentially be generalizable to the clinical setting, and to provide guidelines to strengthen the conduct and relevance of future pre-clinical studies. PMID:25416175

  14. Uncertainty in urban flood damage assessment due to urban drainage modelling and depth-damage curve estimation.

    PubMed

    Freni, G; La Loggia, G; Notaro, V

    2010-01-01

    Due to the increased occurrence of flooding events in urban areas, many procedures for flood damage quantification have been defined in recent decades. The lack of large databases in most cases is overcome by combining the output of urban drainage models and damage curves linking flooding to expected damage. The application of advanced hydraulic models as diagnostic, design and decision-making support tools has become a standard practice in hydraulic research and application. Flooding damage functions are usually evaluated by a priori estimation of potential damage (based on the value of exposed goods) or by interpolating real damage data (recorded during historical flooding events). Hydraulic models have undergone continuous advancements, pushed forward by increasing computer capacity. The details of the flooding propagation process on the surface and the details of the interconnections between underground and surface drainage systems have been studied extensively in recent years, resulting in progressively more reliable models. The same level of was advancement has not been reached with regard to damage curves, for which improvements are highly connected to data availability; this remains the main bottleneck in the expected flooding damage estimation. Such functions are usually affected by significant uncertainty intrinsically related to the collected data and to the simplified structure of the adopted functional relationships. The present paper aimed to evaluate this uncertainty by comparing the intrinsic uncertainty connected to the construction of the damage-depth function to the hydraulic model uncertainty. In this way, the paper sought to evaluate the role of hydraulic model detail level in the wider context of flood damage estimation. This paper demonstrated that the use of detailed hydraulic models might not be justified because of the higher computational cost and the significant uncertainty in damage estimation curves. This uncertainty occurs mainly because a large part of the total uncertainty is dependent on depth-damage curves. Improving the estimation of these curves may provide better results in term of uncertainty reduction than the adoption of detailed hydraulic models.

  15. Backgrounds, radiation damage, and spacecraft orbits

    NASA Astrophysics Data System (ADS)

    Grant, Catherine E.; Miller, Eric D.; Bautz, Mark W.

    2017-08-01

    The scientific utility of any space-based observatory can be limited by the on-orbit charged particle background and the radiation-induced damage. All existing and proposed missions have had to make choices about orbit selection, trading off the radiation environment against other factors. We present simulations from ESA’s SPace ENVironment Information System (SPENVIS) of the radiation environment for spacecraft in a variety of orbits, from Low Earth Orbit (LEO) at multiple inclinations to High Earth Orbit (HEO) to Earth-Sun L2 orbit. We summarize how different orbits change the charged particle background and the radiation damage to the instrument. We also discuss the limitations of SPENVIS simulations, particularly outside the Earth’s trapped radiation and point to new resources attempting to address those limitations.

  16. Frequency Response Function Based Damage Identification for Aerospace Structures

    NASA Astrophysics Data System (ADS)

    Oliver, Joseph Acton

    Structural health monitoring technologies continue to be pursued for aerospace structures in the interests of increased safety and, when combined with health prognosis, efficiency in life-cycle management. The current dissertation develops and validates damage identification technology as a critical component for structural health monitoring of aerospace structures and, in particular, composite unmanned aerial vehicles. The primary innovation is a statistical least-squares damage identification algorithm based in concepts of parameter estimation and model update. The algorithm uses frequency response function based residual force vectors derived from distributed vibration measurements to update a structural finite element model through statistically weighted least-squares minimization producing location and quantification of the damage, estimation uncertainty, and an updated model. Advantages compared to other approaches include robust applicability to systems which are heavily damped, large, and noisy, with a relatively low number of distributed measurement points compared to the number of analytical degrees-of-freedom of an associated analytical structural model (e.g., modal finite element model). Motivation, research objectives, and a dissertation summary are discussed in Chapter 1 followed by a literature review in Chapter 2. Chapter 3 gives background theory and the damage identification algorithm derivation followed by a study of fundamental algorithm behavior on a two degree-of-freedom mass-spring system with generalized damping. Chapter 4 investigates the impact of noise then successfully proves the algorithm against competing methods using an analytical eight degree-of-freedom mass-spring system with non-proportional structural damping. Chapter 5 extends use of the algorithm to finite element models, including solutions for numerical issues, approaches for modeling damping approximately in reduced coordinates, and analytical validation using a composite sandwich plate model. Chapter 6 presents the final extension to experimental systems-including methods for initial baseline correlation and data reduction-and validates the algorithm on an experimental composite plate with impact damage. The final chapter deviates from development and validation of the primary algorithm to discuss development of an experimental scaled-wing test bed as part of a collaborative effort for developing structural health monitoring and prognosis technology. The dissertation concludes with an overview of technical conclusions and recommendations for future work.

  17. Cost of inbreeding in resistance to herbivores in Datura stramonium

    PubMed Central

    Bello-Bedoy, Rafael; Núñez-Farfán, Juan

    2010-01-01

    Background and Aims Experiments show that inbred progenies are frequently more damaged by herbivores than outcrossed progenies, suggesting that selfing is costly when herbivores are present and can increase the magnitude of inbreeding depression in survival and reproductive components of fitness. The present study assesses whether inbreeding increases herbivory and estimates the magnitude of inbreeding depression on reproductive components of fitness in the annual plant Datura stramonium. Methods Two experiments were performed under natural conditions of herbivory to assess the effect of inbreeding on plant damage in D. stramonium. In the first experiment, outcrossed progeny was generated using foreign pollen donors, whereas inbred progeny was produced by self-pollination. In both groups, survival, herbivore damage and reproductive components of fitness were measured. In the second experiment, inbred and outcrossed progenies were produced using only local pollen donors, and only damage by herbivores was measured. Key Results Despite yearly variation in damage caused by the same specialist herbivores, inbred progeny suffered consistently more damage than outcrossed progeny. There was a significant inbreeding depression for fruit number (δ = 0·3), seed number per fruit (δ = 0·19) and seed number per plant (δ = 0·43). Furthermore, significant genetic variation amongst families in the magnitude of inbreeding depression was observed. Discussion The results suggest that the plant's mating system modified the pattern of herbivory by specialist insects in D. stramonium. Inbred plants suffer not only from the genetic cost of low vigour but also from greater damage by herbivores. The mechanism by which inbreeding reduces plant resistance to herbivores remains unknown but is an interesting area for future research. PMID:20237119

  18. Catalog of Residential Depth-Damage Functions Used by the Army Corps of Engineers in Flood Damage Estimation

    DTIC Science & Technology

    1992-05-01

    regression analysis. The strength of any one variable can be estimated along with the strength of the entire model in explaining the variance of percent... applicable a set of damage functions is to a particular situation. Sometimes depth- damage functions are embedded in computer programs which calculate...functions. Chapter Six concludes with recommended policies on the development and application of depth-damage functions. 5 6 CHAPTER TWO CONSTRUCTION OF

  19. Developing Daily Quantitative Damage Estimates From Geospatial Layers To Support Post Event Recovery

    NASA Astrophysics Data System (ADS)

    Woods, B. K.; Wei, L. H.; Connor, T. C.

    2014-12-01

    With the growth of natural hazard data available in near real-time it is increasingly feasible to deliver damage estimates caused by natural disasters. These estimates can be used in disaster management setting or by commercial entities to optimize the deployment of resources and/or routing of goods and materials. This work outlines an end-to-end, modular process to generate estimates of damage caused by severe weather. The processing stream consists of five generic components: 1) Hazard modules that provide quantitate data layers for each peril. 2) Standardized methods to map the hazard data to an exposure layer based on atomic geospatial blocks. 3) Peril-specific damage functions that compute damage metrics at the atomic geospatial block level. 4) Standardized data aggregators, which map damage to user-specific geometries. 5) Data dissemination modules, which provide resulting damage estimates in a variety of output forms. This presentation provides a description of this generic tool set, and an illustrated example using HWRF-based hazard data for Hurricane Arthur (2014). In this example, the Python-based real-time processing ingests GRIB2 output from the HWRF numerical model, dynamically downscales it in conjunctions with a land cover database using a multiprocessing pool, and a just-in-time compiler (JIT). The resulting wind fields are contoured, and ingested into a PostGIS database using OGR. Finally, the damage estimates are calculated at the atomic block level and aggregated to user-defined regions using PostgreSQL queries to construct application specific tabular and graphics output.

  20. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Waldhoff, Stephanie T.; Anthoff, David; Rose, Steven K.

    We use FUND 3.8 to estimate the social cost of four greenhouse gases: carbon dioxide, methane, nitrous oxide, and sulphur hexafluoride emissions. The damage potential for each gas—the ratio of the social cost of the non-carbon dioxide greenhouse gas to the social cost of carbon dioxide—is also estimated. The damage potentials are compared to several metrics, focusing in particular on the global warming potentials, which are frequently used to measure the trade-off between gases in the form of carbon dioxide equivalents. We find that damage potentials could be significantly higher than global warming potentials. This finding implies that previous papersmore » have underestimated the relative importance of reducing non-carbon dioxide greenhouse gas emissions from an economic damage perspective. We show results for a range of sensitivity analyses: carbon dioxide fertilization on agriculture productivity, terrestrial feedbacks, climate sensitivity, discounting, equity weighting, and socioeconomic and emissions scenarios. The sensitivity of the results to carbon dioxide fertilization is a primary focus as it is an important element of climate change that has not been considered in much of the previous literature. We estimate that carbon dioxide fertilization has a large positive impact that reduces the social cost of carbon dioxide with a much smaller effect on the other greenhouse gases. As a result, our estimates of the damage potentials of methane and nitrous oxide are much higher compared to estimates that ignore carbon dioxide fertilization. As a result, our base estimates of the damage potential for methane and nitrous oxide that include carbon dioxide fertilization are twice their respective global warming potentials. Our base estimate of the damage potential of sulphur hexafluoride is similar to the one previous estimate, both almost three times the global warming potential.« less

  1. Evidence of man-vector contact in torn long-lasting insecticide-treated nets

    PubMed Central

    2013-01-01

    Background Studies indicate that physical damage to long-lasting insecticide-treated nets (LLINs) occurs at a surprisingly rapid rate following net distribution. To what extent does such damage affect the impact of LLINs? Can vectors pass a compromised LLIN barrier to bite? Do more resistant vectors enter the insecticide-treated nets (ITNs) through holes? Methods The study was carried out in three geo-locations. Two types of LLINs (polyester and polyethylene) with ‘standardized’ physical damage were compared with similarly damaged, but non-insecticidal (control) nets. The proportionate Holes Index (pHI) of each net was 276. Mosquitoes were captured inside the nets, identified taxonomically, and subjected to molecular analysis to estimate Knock-down resistance (Kdr) frequency. Results The most commonly observed species was Anopheles gambiae, accounting for approximately 70% (1,076/1,550) of the total mosquitoes collected both in LLINs and non-insecticidal nets. When compared with controls, number of vectors captured in torn LLINs was significantly reduced. Nonetheless in a night, an average of 5 An. gambiae s.l could enter the damaged LLINs to bite. Similar numbers of resistant mosquitoes were collected in both LLINs and non-insecticidal (control) nets (p > 0.05). Conclusions At a pHI of 276, man-vector contact was observed in torn LLINs. The insecticide at the surface of LLINs could only reduce the number of vectors. Resistant mosquitoes have opportunity to enter both non-insecticidal (control) nets and LLINs to bite. PMID:23941585

  2. A finite element method model to simulate laser interstitial thermo therapy in anatomical inhomogeneous regions

    PubMed Central

    Mohammed, Yassene; Verhey, Janko F

    2005-01-01

    Background Laser Interstitial ThermoTherapy (LITT) is a well established surgical method. The use of LITT is so far limited to homogeneous tissues, e.g. the liver. One of the reasons is the limited capability of existing treatment planning models to calculate accurately the damage zone. The treatment planning in inhomogeneous tissues, especially of regions near main vessels, poses still a challenge. In order to extend the application of LITT to a wider range of anatomical regions new simulation methods are needed. The model described with this article enables efficient simulation for predicting damaged tissue as a basis for a future laser-surgical planning system. Previously we described the dependency of the model on geometry. With the presented paper including two video files we focus on the methodological, physical and mathematical background of the model. Methods In contrast to previous simulation attempts, our model is based on finite element method (FEM). We propose the use of LITT, in sensitive areas such as the neck region to treat tumours in lymph node with dimensions of 0.5 cm – 2 cm in diameter near the carotid artery. Our model is based on calculations describing the light distribution using the diffusion approximation of the transport theory; the temperature rise using the bioheat equation, including the effect of microperfusion in tissue to determine the extent of thermal damage; and the dependency of thermal and optical properties on the temperature and the injury. Injury is estimated using a damage integral. To check our model we performed a first in vitro experiment on porcine muscle tissue. Results We performed the derivation of the geometry from 3D ultrasound data and show for this proposed geometry the energy distribution, the heat elevation, and the damage zone. Further on, we perform a comparison with the in-vitro experiment. The calculation shows an error of 5% in the x-axis parallel to the blood vessel. Conclusions The FEM technique proposed can overcome limitations of other methods and enables an efficient simulation for predicting the damage zone induced using LITT. Our calculations show clearly that major vessels would not be damaged. The area/volume of the damaged zone calculated from both simulation and in-vitro experiment fits well and the deviation is small. One of the main reasons for the deviation is the lack of accurate values of the tissue optical properties. In further experiments this needs to be validated. PMID:15631630

  3. Significant Suppression of CT Radiation-Induced DNA Damage in Normal Human Cells by the PrC-210 Radioprotector.

    PubMed

    Jermusek, Frank; Benedict, Chelsea; Dreischmeier, Emma; Brand, Michael; Uder, Michael; Jeffery, Justin J; Ranallo, Frank N; Fahl, William E

    2018-05-21

    While computed tomography (CT) is now commonly used and considered to be clinically valuable, significant DNA double-strand breaks (γ-H2AX foci) in white blood cells from adult and pediatric CT patients have been frequently reported. In this study to determine whether γ-H2AX foci and X-ray-induced naked DNA damage are suppressed by administration of the PrC-210 radioprotector, human blood samples were irradiated in a CT scanner at 50-150 mGy with or without PrC-210, and γ-H2AX foci were scored. X-ray-induced naked DNA damage was also studied, and the DNA protective efficacy of PrC-210 was compared against 12 other common "antioxidants." PrC-210 reduced CT radiation-induced γ-H2AX foci in white blood cells to near background ( P < 0.0001) at radiation doses of 50-150 mGy. PrC-210 was most effective among the 13 "antioxidants" in reducing naked DNA X-ray damage, and its addition at 30 s before an • OH pulse reduced to background the • OH insult that otherwise induced >95% DNA damage. A systemic PrC-210 dose known to confer 100% survival in irradiated mice had no discernible effect on micro-CT image signal-to-noise ratio and CT image integrity. PrC-210 suppressed DNA damage to background or near background in each of these assay systems, thus supporting its development as a radioprotector for humans in multiple radiation exposure settings.

  4. Structural Health Monitoring for Impact Damage in Composite Structures.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Roach, Dennis P.; Raymond Bond; Doug Adams

    Composite structures are increasing in prevalence throughout the aerospace, wind, defense, and transportation industries, but the many advantages of these materials come with unique challenges, particularly in inspecting and repairing these structures. Because composites of- ten undergo sub-surface damage mechanisms which compromise the structure without a clear visual indication, inspection of these components is critical to safely deploying composite re- placements to traditionally metallic structures. Impact damage to composites presents one of the most signi fi cant challenges because the area which is vulnerable to impact damage is generally large and sometimes very dif fi cult to access. This workmore » seeks to further evolve iden- ti fi cation technology by developing a system which can detect the impact load location and magnitude in real time, while giving an assessment of the con fi dence in that estimate. Fur- thermore, we identify ways by which impact damage could be more effectively identi fi ed by leveraging impact load identi fi cation information to better characterize damage. The impact load identi fi cation algorithm was applied to a commercial scale wind turbine blade, and results show the capability to detect impact magnitude and location using a single accelerometer, re- gardless of sensor location. A technique for better evaluating the uncertainty of the impact estimates was developed by quantifying how well the impact force estimate meets the assump- tions underlying the force estimation technique. This uncertainty quanti fi cation technique was found to reduce the 95% con fi dence interval by more than a factor of two for impact force estimates showing the least uncertainty, and widening the 95% con fi dence interval by a fac- tor of two for the most uncertain force estimates, avoiding the possibility of understating the uncertainty associated with these estimates. Linear vibration based damage detection tech- niques were investigated in the context of structural stiffness reductions and impact damage. A method by which the sensitivity to damage could be increased for simple structures was presented, and the challenges of applying that technique to a more complex structure were identi fi ed. The structural dynamic changes in a weak adhesive bond were investigated, and the results showed promise for identifying weak bonds that show little or no static reduction in stiffness. To address these challenges in identifying highly localized impact damage, the possi- bility of detecting damage through nonlinear dynamic characteristics was also identi fi ed, with a proposed technique which would leverage impact location estimates to enable the detection of impact damage. This nonlinear damage identi fi cation concept was evaluated on a composite panel with a substructure disbond, and the results showed that the nonlinear dynamics at the damage site could be observed without a baseline healthy reference. By further developing impact load identi fi cation technology and combining load and damage estimation techniques into an integrated solution, the challenges associated with impact detection in composite struc- tures can be effectively solved, thereby reducing costs, improving safety, and enhancing the operational readiness and availability of high value assets.« less

  5. Damage classification and estimation in experimental structures using time series analysis and pattern recognition

    NASA Astrophysics Data System (ADS)

    de Lautour, Oliver R.; Omenzetter, Piotr

    2010-07-01

    Developed for studying long sequences of regularly sampled data, time series analysis methods are being increasingly investigated for the use of Structural Health Monitoring (SHM). In this research, Autoregressive (AR) models were used to fit the acceleration time histories obtained from two experimental structures: a 3-storey bookshelf structure and the ASCE Phase II Experimental SHM Benchmark Structure, in undamaged and limited number of damaged states. The coefficients of the AR models were considered to be damage-sensitive features and used as input into an Artificial Neural Network (ANN). The ANN was trained to classify damage cases or estimate remaining structural stiffness. The results showed that the combination of AR models and ANNs are efficient tools for damage classification and estimation, and perform well using small number of damage-sensitive features and limited sensors.

  6. Characterization of the antiproliferative activity of Xylopia aethiopica

    PubMed Central

    2012-01-01

    Background Xylopia aethiopica, a plant found throughout West Africa, has both nutritional and medicinal uses. The present study aims to characterize the effects of extracts of this plant on cancer cells. Results We report that X. aethiopica extract prepared with 70% ethanol has antiproliferative activity against a panel of cancer cell lines. The IC50 was estimated at 12 μg/ml against HCT116 colon cancer cells, 7.5 μg/ml and > 25 μg/ml against U937 and KG1a leukemia cells, respectively. Upon fractionation of the extract by HPLC, the active fraction induced DNA damage, cell cycle arrest in G1 phase and apoptotic cell death. By using NMR and mass spectrometry, we determined the structure of the active natural product in the HPLC fraction as ent-15-oxokaur-16-en-19-oic acid. Conclusion The main cytotoxic and DNA-damaging compound in ethanolic extracts of Xylopia aethiopica is ent-15-oxokaur-16-en-19-oic acid. PMID:22409878

  7. Variability in Estrogen-Metabolizing Genes and Their Association with Genomic Instability in Untreated Breast Cancer Patients and Healthy Women

    PubMed Central

    Alves dos Santos, Raquel; Teixeira, Ana Cláudia; Mayorano, Mônica Beatriz; Carrara, Hélio Humberto Angotti; Moreira de Andrade, Jurandyr; Takahashi, Catarina Satie

    2011-01-01

    In the present study, we investigated the relationship between polymorphisms in the estrogen-metabolizing genes CYP17, CYP1B1, CYP1A1, and COMT and genomic instability in the peripheral blood lymphocytes of 62 BC patients and 62 controls considering that increased or prolonged exposure to estrogen can damage the DNA molecule and increase the genomic instability process in breast tissue. Our data demonstrated increased genomic instability in BC patients and that individuals with higher frequencies of MN exhibited higher risk to BC when belonging Val/Met genotype of the COMT gene. We also observed that CYP17 and CYP1A1 polymorphisms can modify the risk to BC depending on the menopause status. We can conclude that the genetic background in estrogen metabolism pathway can modulate chromosome damage in healthy controls and patients and thereby influence the risk to BC. These findings suggest the importance to ally biomarkers of susceptibility and effects to estimate risk groups. PMID:21716904

  8. Assessment of Crop Damage by Protected Wild Mammalian Herbivores on the Western Boundary of Tadoba-Andhari Tiger Reserve (TATR), Central India

    PubMed Central

    Bayani, Abhijeet; Tiwade, Dilip; Dongre, Ashok; Dongre, Aravind P.; Phatak, Rasika; Watve, Milind

    2016-01-01

    Crop raiding by wild herbivores close to an area of protected wildlife is a serious problem that can potentially undermine conservation efforts. Since there is orders of magnitude difference between farmers’ perception of damage and the compensation given by the government, an objective and realistic estimate of damage was found essential. We employed four different approaches to estimate the extent of and patterns in crop damage by wild herbivores along the western boundary of Tadoba-Andhari Tiger Reserve in the state of Maharashtra, central India. These approaches highlight different aspects of the problem but converge on an estimated damage of over 50% for the fields adjacent to the forest, gradually reducing in intensity with distance. We found that the visual damage assessment method currently employed by the government for paying compensation to farmers was uncorrelated to and grossly underestimated actual damage. The findings necessitate a radical rethinking of policies to assess, mitigate as well as compensate for crop damage caused by protected wildlife species. PMID:27093293

  9. Ecosystem services impacts associated with environmental ...

    EPA Pesticide Factsheets

    Nitrogen release to the environment from human activities can have important and costly impacts on human health, recreation, transportation, fisheries, and ecosystem health. Recent efforts to quantify these damage costs have identified annual damages associated with reactive nitrogen release to the EU and US in the hundreds of billions of US dollars (USD). The general approach used to estimate these damages associated with reactive nitrogen are derived from a variety of methods to estimate economic damages, for example, impacts to human respiratory health in terms of hospital visits and mortality, willingness to pay to improve a water body and costs to replace or treat drinking water systems affected by nitrate or cyanotoxin contamination. These values are then extrapolated to other areas to develop the damage cost estimates that are probably best seen as potential damage costs, particularly for aquatic ecosystems. We seek to provide an additional verification of these potential damages using data assembled by the US EPA for case studies of measured costs of nutrient impacts across the US from 2000-2012. We compare the spatial distribution and the magnitude of these costs with the spatial distribution and magnitude of costs from HUC8 watershed units across the US by Sobota et al. (2015). We anticipate that this analysis will provide a ground truthing of existing damage cost estimates, and continue to support the incorporation of cost and benefit informatio

  10. Probabilistic flood damage modelling at the meso-scale

    NASA Astrophysics Data System (ADS)

    Kreibich, Heidi; Botto, Anna; Schröter, Kai; Merz, Bruno

    2014-05-01

    Decisions on flood risk management and adaptation are usually based on risk analyses. Such analyses are associated with significant uncertainty, even more if changes in risk due to global change are expected. Although uncertainty analysis and probabilistic approaches have received increased attention during the last years, they are still not standard practice for flood risk assessments. Most damage models have in common that complex damaging processes are described by simple, deterministic approaches like stage-damage functions. Novel probabilistic, multi-variate flood damage models have been developed and validated on the micro-scale using a data-mining approach, namely bagging decision trees (Merz et al. 2013). In this presentation we show how the model BT-FLEMO (Bagging decision Tree based Flood Loss Estimation MOdel) can be applied on the meso-scale, namely on the basis of ATKIS land-use units. The model is applied in 19 municipalities which were affected during the 2002 flood by the River Mulde in Saxony, Germany. The application of BT-FLEMO provides a probability distribution of estimated damage to residential buildings per municipality. Validation is undertaken on the one hand via a comparison with eight other damage models including stage-damage functions as well as multi-variate models. On the other hand the results are compared with official damage data provided by the Saxon Relief Bank (SAB). The results show, that uncertainties of damage estimation remain high. Thus, the significant advantage of this probabilistic flood loss estimation model BT-FLEMO is that it inherently provides quantitative information about the uncertainty of the prediction. Reference: Merz, B.; Kreibich, H.; Lall, U. (2013): Multi-variate flood damage assessment: a tree-based data-mining approach. NHESS, 13(1), 53-64.

  11. Probabilistic estimation of numbers and costs of future landslides in the San Francisco Bay region

    USGS Publications Warehouse

    Crovelli, R.A.; Coe, J.A.

    2009-01-01

    We used historical records of damaging landslides triggered by rainstorms and a newly developed Probabilistic Landslide Assessment Cost Estimation System (PLACES) to estimate the numbers and direct costs of future landslides in the 10-county San Francisco Bay region. Historical records of damaging landslides in the region are incomplete. Therefore, our estimates of numbers and costs of future landslides are minimal estimates. The estimated mean annual number of future damaging landslides for the entire 10-county region is about 65. Santa Cruz County has the highest estimated mean annual number of damaging future landslides (about 18), whereas Napa, San Francisco, and Solano Counties have the lowest estimated mean numbers of damaging landslides (about 1 each). The estimated mean annual cost of future landslides in the entire region is about US $14.80 million (year 2000 $). The estimated mean annual cost is highest for San Mateo County ($3.24 million) and lowest for Solano County ($0.18 million). The annual per capita cost for the entire region will be about $2.10. Santa Cruz County will have the highest annual per capita cost at $8.45, whereas San Francisco County will have the lowest per capita cost at $0.31. Normalising costs by dividing by the percentage of land area with slopes equal to or greater than 17% indicates that San Francisco County will have the highest cost per square km ($7,101), whereas Santa Clara County will have the lowest cost per square km ($229). These results indicate that the San Francisco Bay region has one of the highest levels of landslide risk in the United States. Compared with landslide cost estimates from the rest of the world, the risk level in the Bay region seems high, but not exceptionally high.

  12. Applications of ASFCM(Assessment System of Flood Control Measurement) in Typhoon Committee Members

    NASA Astrophysics Data System (ADS)

    Kim, C.

    2013-12-01

    Due to extreme weather environment such as global warming and greenhouse effect, the risks of having flood damage has been increased with larger scale of flood damages. Therefore, it became necessary to consider modifying climate change, flood damage and its scale to the previous dimension measurement evaluation system. In this regard, it is needed to establish a comprehensive and integrated system to evaluate the most optimized measures for flood control through eliminating uncertainties of socio-economic impacts. Assessment System of Structural Flood Control Measures (ASFCM) was developed for determining investment priorities of the flood control measures and establishing the social infrastructure projects. ASFCM consists of three modules: 1) the initial setup and inputs module, 2) the flood and damage estimation module, and 3) the socio-economic analysis module. First, we have to construct the D/B for flood damage estimation, which is the initial and input data about the estimation unit, property, historical flood damages, and applied area's topographic & hydrological data. After that, it is important to classify local characteristic for constructing flood damage data. Five local characteristics (big city, medium size city, small city, farming area, and mountain area) are classified by criterion of application (population density). Next step is the floodplain simulation with HEC-RAS which is selected to simulate inundation. Through inputting the D/B and damage estimation, it is able to estimate the total damage (only direct damage) that is the amount of cost to recover the socio-economic activities back to the safe level before flood did occur. The last module suggests the economic analysis index (B/C ratio) with Multidimensional Flood Damage Analysis. Consequently, ASFCM suggests the reference index in constructing flood control measures and planning non-structural systems to reduce water-related damage. It is possible to encourage flood control planners and managers to consider and apply the socio-economic analysis results. ASFCM was applied in Republic of Korea, Thailand and Philippines to review efficiency and applicability. Figure 1. ASFCM Application(An-yang Stream, Republic of Korea)

  13. D-PSA-K: A Model for Estimating the Accumulated Potential Damage on Kiwifruit Canes Caused by Bacterial Canker during the Growing and Overwintering Seasons.

    PubMed

    Do, Ki Seok; Chung, Bong Nam; Joa, Jae Ho

    2016-12-01

    We developed a model, termed D-PSA-K, to estimate the accumulated potential damage on kiwifruit canes caused by bacterial canker during the growing and overwintering seasons. The model consisted of three parts including estimation of the amount of necrotic lesion in a non-frozen environment, the rate of necrosis increase in a freezing environment during the overwintering season, and the amount of necrotic lesion on kiwifruit canes caused by bacterial canker during the overwintering and growing seasons. We evaluated the model's accuracy by comparing the observed maximum disease incidence on kiwifruit canes against the damage estimated using weather and disease data collected at Wando during 1994-1997 and at Seogwipo during 2014-2015. For the Hayward cultivar, D-PSA-K estimated the accumulated damage as approximately nine times the observed maximum disease incidence. For the Hort16A cultivar, the accumulated damage estimated by D-PSA-K was high when the observed disease incidence was high. D-PSA-K could assist kiwifruit growers in selecting optimal sites for kiwifruit cultivation and establishing improved production plans by predicting the loss in kiwifruit production due to bacterial canker, using past weather or future climate change data.

  14. Sequential structural damage diagnosis algorithm using a change point detection method

    NASA Astrophysics Data System (ADS)

    Noh, H.; Rajagopal, R.; Kiremidjian, A. S.

    2013-11-01

    This paper introduces a damage diagnosis algorithm for civil structures that uses a sequential change point detection method. The general change point detection method uses the known pre- and post-damage feature distributions to perform a sequential hypothesis test. In practice, however, the post-damage distribution is unlikely to be known a priori, unless we are looking for a known specific type of damage. Therefore, we introduce an additional algorithm that estimates and updates this distribution as data are collected using the maximum likelihood and the Bayesian methods. We also applied an approximate method to reduce the computation load and memory requirement associated with the estimation. The algorithm is validated using a set of experimental data collected from a four-story steel special moment-resisting frame and multiple sets of simulated data. Various features of different dimensions have been explored, and the algorithm was able to identify damage, particularly when it uses multidimensional damage sensitive features and lower false alarm rates, with a known post-damage feature distribution. For unknown feature distribution cases, the post-damage distribution was consistently estimated and the detection delays were only a few time steps longer than the delays from the general method that assumes we know the post-damage feature distribution. We confirmed that the Bayesian method is particularly efficient in declaring damage with minimal memory requirement, but the maximum likelihood method provides an insightful heuristic approach.

  15. A Hybrid Approach to Composite Damage and Failure Analysis Combining Synergistic Damage Mechanics and Peridynamics

    DTIC Science & Technology

    2016-03-31

    fiber distributions. Task 2.1 is concerned with damage evolution in a peridynamic model of poroelastic materials. Initial results for both tasks are...distributions. Task 2.1 is concerned with damage evolution in a peridynamic model of poroelastic materials. Initial results for both tasks are reported and...Task 2.1: Damage evolution in a peridynamic model of poroelastic materials. Background and Motivation In order to model the presence of pores and

  16. Estimating Cone and Seed Production and Monitoring Pest Damage in Southern Pine Seed Orchards

    Treesearch

    Carl W. Fatzinger; H. David Muse; Thomas Miller; Helen T. Bhattacharyya

    1988-01-01

    Field sampling procedures and computer programs are described for monitoring seed production and pest damage in southern pine seed orchards. The system estimates total orchard yields of female strobili and seeds, quantifies pest damage, determines times of year when losses occur, and produces life tables for female strobili. An example is included to illustrate the...

  17. A Study on Active Disaster Management System for Standardized Emergency Action Plan using BIM and Flood Damage Estimation Techniques

    NASA Astrophysics Data System (ADS)

    Jeong, C.; Om, J.; Hwang, J.; Joo, K.; Heo, J.

    2013-12-01

    In recent, the frequency of extreme flood has been increasing due to climate change and global warming. Highly flood damages are mainly caused by the collapse of flood control structures such as dam and dike. In order to reduce these disasters, the disaster management system (DMS) through flood forecasting, inundation mapping, EAP (Emergency Action Plan) has been studied. The estimation of inundation damage and practical EAP are especially crucial to the DMS. However, it is difficult to predict inundation and take a proper action through DMS in real emergency situation because several techniques for inundation damage estimation are not integrated and EAP is supplied in the form of a document in Korea. In this study, the integrated simulation system including rainfall frequency analysis, rainfall-runoff modeling, inundation prediction, surface runoff analysis, and inland flood analysis was developed. Using this system coupled with standard GIS data, inundation damage can be estimated comprehensively and automatically. The standard EAP based on BIM (Building Information Modeling) was also established in this system. It is, therefore, expected that the inundation damages through this study over the entire area including buildings can be predicted and managed.

  18. Muon trackers for imaging a nuclear reactor

    NASA Astrophysics Data System (ADS)

    Kume, N.; Miyadera, H.; Morris, C. L.; Bacon, J.; Borozdin, K. N.; Durham, J. M.; Fuzita, K.; Guardincerri, E.; Izumi, M.; Nakayama, K.; Saltus, M.; Sugita, T.; Takakura, K.; Yoshioka, K.

    2016-09-01

    A detector system for assessing damage to the cores of the Fukushima Daiichi nuclear reactors by using cosmic-ray muon tomography was developed. The system consists of a pair of drift-tube tracking detectors of 7.2× 7.2-m2 area. Each muon tracker consists of 6 x-layer and 6 y-layer drift-tube detectors. Each tracker is capable of measuring muon tracks with 12 mrad angular resolutions, and is capable of operating under 50-μ Sv/h radiation environment by removing gamma induced background with a novel time-coincidence logic. An estimated resolution to observe nuclear fuel debris at Fukushima Daiichi is 0.3 m when the core is imaged from outside the reactor building.

  19. Improved Sizing of Impact Damage in Composites Based on Thermographic Response

    NASA Technical Reports Server (NTRS)

    Winfree, William P.; Howell Patricia A.; Leckey, Cara A.; Rogge, Matthew D.

    2013-01-01

    Impact damage in thin carbon fiber reinforced polymer composites often results in a relatively small region of damage at the front surface, with increasing damage near the back surface. Conventional methods for reducing the pulsed thermographic responses of the composite tend to underestimate the size of the back surface damage, since the smaller near surface damage gives the largest thermographic indication. A method is presented for reducing the thermographic data to produce an estimated size for the impact damage that is much closer to the size of the damage estimated from other NDE techniques such as microfocus x-ray computed tomography and pulse echo ultrasonics. Examples of the application of the technique to experimental data acquired on specimens with impact damage are presented. The method is also applied to the results of thermographic simulations to investigate the limitations of the technique.

  20. New Method for Estimating Landslide Losses for Major Winter Storms in California.

    NASA Astrophysics Data System (ADS)

    Wills, C. J.; Perez, F. G.; Branum, D.

    2014-12-01

    We have developed a prototype system for estimating the economic costs of landslides due to winter storms in California. This system uses some of the basic concepts and estimates of the value of structures from the HAZUS program developed for FEMA. Using the only relatively complete landslide loss data set that we could obtain, data gathered by the City of Los Angeles in 1978, we have developed relations between landslide susceptibility and loss ratio for private property (represented as the value of wood frame structures from HAZUS). The landslide loss ratios estimated from the Los Angeles data are calibrated using more generalized data from the 1982 storms in the San Francisco Bay area to develop relationships that can be used to estimate loss for any value of 2-day or 30-day rainfall averaged over a county. The current estimates for major storms are long projections from very small data sets, subject to very large uncertainties, so provide a very rough estimate of the landslide damage to structures and infrastructure on hill slopes. More importantly, the system can be extended and improved with additional data and used to project landslide losses in future major winter storms. The key features of this system—the landslide susceptibility map, the relationship between susceptibility and loss ratio, and the calibration of estimates against losses in past storms—can all be improved with additional data. Most importantly, this study highlights the importance of comprehensive studies of landslide damage. Detailed surveys of landslide damage following future storms that include locations and amounts of damage for all landslides within an area are critical for building a well-calibrated system to project future landslide losses. Without an investment in post-storm landslide damage surveys, it will not be possible to improve estimates of the magnitude or distribution of landslide damage, which can range up to billions of dollars.

  1. Diagnostic value of cystatin C for diagnosis of early renal damages in type 2 diabetic mellitus patients: The first experience in Iran

    PubMed Central

    Javanmardi, Mitra; Azadi, Namam-Ali; Amini, Sabrieh; Abdi, Mohammad

    2015-01-01

    Background: Diabetic nephropathy (DN) is one of the most important complications of diabetes mellitus. Now-a-days, cystatin C (CysC) is introduced as a new marker for diagnosis of renal damages; however, use of this marker in clinical laboratories is still controversial. The present study was aimed to evaluate the diagnostic value of serum CysC for early detection or monitoring treatment of kidney damages in the Kurdish people with type 2 diabetes mellitus. Materials and Methods: Glomerular filtration rate (GFR) was estimated by Modification of Diet in Renal Disease formula. Serum CysC and urine microalbumin were also measured in 126 diabetic and healthy subjects. Blood glycated hemoglobin (Hb) also measured in all healthy and diabetic patients. Two independent samples t-test, Mann-Whitney U-test, one-way ANOVA, and Kruskal-Wallis test, as well as Pearson/Spearman correlation coefficient statistical tests were used as appropriate. Results: Serum CysC was higher (1312.41 ng/ml) in diabetic patients with GFR <60 ml/min than other subjects (993.25 ng/ml) (patients with normal kidney function and healthy subjects). A borderline significant correlation between CysC and estimating GFR (rs = −0.16, P = 0.05) but highly significant with microalbumin (rs = 0.22, P = 0.014) was observed. Serum CysC sensitivity, negative and positive predictive values were 100 and 4%. Conclusion: CysC cover variation of GFR and urine microalbumin, but it cannot be used as a surrogating marker of glycated Hb. According to our results, it seems that serum CysC is a useful marker for screening of DN; but it cannot be used for monitoring of treatment in diabetic patients. PMID:26600832

  2. High dietary antioxidant intakes are associated with decreased chromosome translocation frequency in airline pilots1234

    PubMed Central

    Petersen, Martin R; Sigurdson, Alice J; Sampson, Laura A; Ward, Elizabeth M

    2009-01-01

    Background: Dietary antioxidants may protect against DNA damage induced by endogenous and exogenous sources, including ionizing radiation (IR), but data from IR-exposed human populations are limited. Objective: The objective was to examine the association between the frequency of chromosome translocations, as a biomarker of cumulative DNA damage, and intakes of vitamins C and E and carotenoids in 82 male airline pilots. Design: Dietary intakes were estimated by using a self-administered semiquantitative food-frequency questionnaire. Translocations were scored by using fluorescence in situ hybridization with whole chromosome paints. Negative binomial regression was used to estimate rate ratios and 95% CIs, adjusted for potential confounders. Results: Significant and inverse associations were observed between translocation frequency and intakes of vitamin C, β-carotene, β-cryptoxanthin, and lutein-zeaxanthin from food (P < 0.05). Translocation frequency was not associated with the intake of vitamin E, α-carotene, or lycopene from food; total vitamin C or E from food and supplements; or vitamin C or E or multivitamin supplements. The adjusted rate ratios (95% CI) for ≥median compared with

  3. Aircraft ground damage and the use of predictive models to estimate costs

    NASA Astrophysics Data System (ADS)

    Kromphardt, Benjamin D.

    Aircraft are frequently involved in ground damage incidents, and repair costs are often accepted as part of doing business. The Flight Safety Foundation (FSF) estimates ground damage to cost operators $5-10 billion annually. Incident reports, documents from manufacturers or regulatory agencies, and other resources were examined to better understand the problem of ground damage in aviation. Major contributing factors were explained, and two versions of a computer-based model were developed to project costs and show what is possible. One objective was to determine if the models could match the FSF's estimate. Another objective was to better understand cost savings that could be realized by efforts to further mitigate the occurrence of ground incidents. Model effectiveness was limited by access to official data, and assumptions were used if data was not available. However, the models were determined to sufficiently estimate the costs of ground incidents.

  4. System for estimating fatigue damage

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    LeMonds, Jeffrey; Guzzo, Judith Ann; Liu, Shaopeng

    In one aspect, a system for estimating fatigue damage in a riser string is provided. The system includes a plurality of accelerometers which can be deployed along a riser string and a communications link to transmit accelerometer data from the plurality of accelerometers to one or more data processors in real time. With data from a limited number of accelerometers located at sensor locations, the system estimates an optimized current profile along the entire length of the riser including riser locations where no accelerometer is present. The optimized current profile is then used to estimate damage rates to individual risermore » components and to update a total accumulated damage to individual riser components. The number of sensor locations is small relative to the length of a deepwater riser string, and a riser string several miles long can be reliably monitored along its entire length by fewer than twenty sensor locations.« less

  5. Estimating the costs of landslide damage in the United States

    USGS Publications Warehouse

    Fleming, Robert W.; Taylor, Fred A.

    1980-01-01

    Landslide damages are one of the most costly natural disasters in the United States. A recent estimate of the total annual cost of landslide damage is in excess of $1 billion {Schuster, 1978}. The damages can be significantly reduced, however, through the combined action of technical experts, government, and the public. Before they can be expected to take action, local governments need to have an appreciation of costs of damage in their areas of responsibility and of the reductions in losses that can be achieved. Where studies of cost of landslide damages have been conducted, it is apparent that {1} costs to the public and private sectors of our economy due to landslide damage are much larger than anticipated; {2} taxpayers and public officials generally are unaware of the magnitude of the cost, owing perhaps to the lack of any centralization of data; and {3} incomplete records and unavailability of records result in lower reported costs than actually were incurred. The U.S. Geological Survey has developed a method to estimate the cost of landslide damages in regional and local areas and has applied the method in three urban areas and one rural area. Costs are for different periods and are unadjusted for inflation; therefore, strict comparisons of data from different years should be avoided. Estimates of the average annual cost of landslide damage for the urban areas studied are $5,900,000 in the San Francisco Bay area; $4,000,000 in Allegheny County, Pa.; and $5,170,000 in Hamilton County, Ohio. Adjusting these figures for the population of each area, the annual cost of damages per capita are $1.30 in the nine-county San Francisco Bay region; $2.50 in Allegheny County, Pa.; and $5.80 in Hamilton County, Ohio. On the basis of data from other sources, the estimated annual damages on a per capita basis for the City of Los Angeles, Calif., are about $1.60. If the costs were available for the damages from landslides in Los Angeles in 1977-78 and 1979-80, the annual per capita costs probably would be much larger. The landslide near the rural community of Manti, Utah, caused an expenditure of about $1,800,000 or about $1,000 per person during the period 1974-76. Because a recurrence for such a landslide cannot be established, it is not possible to develop a meaningful estimate of annual per capita damages. Communities are urged to examine their costs of landslide damage and to evaluate the feasibility of several alternative programs that, for a modest investment, could significantly reduce these losses.

  6. Economic valuation of landslide damage in hilly regions: a case study from Flanders, Belgium.

    PubMed

    Vranken, Liesbet; Van Turnhout, Pieter; Van Den Eeckhaut, Miet; Vandekerckhove, Liesbeth; Poesen, Jean

    2013-03-01

    Several regions around the globe are at risk of incurring damage from landslides, but only few studies have concentrated on a quantitative estimate of the overall damage caused by landslides at a regional scale. This study therefore starts with a quantitative economic assessment of the direct and indirect damage caused by landslides in a 2,910 km study area located west of Brussels, a low-relief region susceptible to landslides. Based on focus interviews as well as on semi-structured interviews with homeowners, civil servants and the owners and providers of lifelines such as electricity and sewage, a quantitative damage assessment is provided. For private properties (houses, forest and pasture land) we estimate the real estate and production value losses for different damage scenarios, while for public infrastructure the costs of measures to repair and prevent landslide induced damage are estimated. In addition, the increase in amenity value of forests and grasslands due to the occurrence of landslides is also calculated. The study illustrates that a minority of land (only 2.3%) within the study area is used for dwellings, roads and railway lines, but that these land use types are responsible for the vast majority of the economic damage due to the occurrence of landslides. The annual cost of direct damage due to landsliding amounts to 688,148 €/year out of which 550,740 €/year for direct damage to houses, while the annual indirect damage augments to 3,020,049 €/year out of which 2,007,375 €/year for indirect damage to real estate. Next, the study illustrates that the increase of the amenity value of forests and grasslands outweighs the production value loss. As such the study does not only provide quantitative input data for the estimation of future risks, but also important information for government officials as it clearly informs about the costs associated with certain land use types in landslide areas. Copyright © 2013 Elsevier B.V. All rights reserved.

  7. Damage diagnosis algorithm using a sequential change point detection method with an unknown distribution for damage

    NASA Astrophysics Data System (ADS)

    Noh, Hae Young; Rajagopal, Ram; Kiremidjian, Anne S.

    2012-04-01

    This paper introduces a damage diagnosis algorithm for civil structures that uses a sequential change point detection method for the cases where the post-damage feature distribution is unknown a priori. This algorithm extracts features from structural vibration data using time-series analysis and then declares damage using the change point detection method. The change point detection method asymptotically minimizes detection delay for a given false alarm rate. The conventional method uses the known pre- and post-damage feature distributions to perform a sequential hypothesis test. In practice, however, the post-damage distribution is unlikely to be known a priori. Therefore, our algorithm estimates and updates this distribution as data are collected using the maximum likelihood and the Bayesian methods. We also applied an approximate method to reduce the computation load and memory requirement associated with the estimation. The algorithm is validated using multiple sets of simulated data and a set of experimental data collected from a four-story steel special moment-resisting frame. Our algorithm was able to estimate the post-damage distribution consistently and resulted in detection delays only a few seconds longer than the delays from the conventional method that assumes we know the post-damage feature distribution. We confirmed that the Bayesian method is particularly efficient in declaring damage with minimal memory requirement, but the maximum likelihood method provides an insightful heuristic approach.

  8. Detection of osmotic damages in GRP boat hulls

    NASA Astrophysics Data System (ADS)

    Krstulović-Opara, L.; Domazet, Ž.; Garafulić, E.

    2013-09-01

    Infrared thermography as a tool of non-destructive testing is method enabling visualization and estimation of structural anomalies and differences in structure's topography. In presented paper problem of osmotic damage in submerged glass reinforced polymer structures is addressed. The osmotic damage can be detected by a simple humidity gauging, but for proper evaluation and estimation testing methods are restricted and hardly applicable. In this paper it is demonstrated that infrared thermography, based on estimation of heat wave propagation, can be used. Three methods are addressed; Pulsed thermography, Fast Fourier Transform and Continuous Morlet Wavelet. An additional image processing based on gradient approach is applied on all addressed methods. It is shown that the Continuous Morlet Wavelet is the most appropriate method for detection of osmotic damage.

  9. Applying stochastic small-scale damage functions to German winter storms

    NASA Astrophysics Data System (ADS)

    Prahl, B. F.; Rybski, D.; Kropp, J. P.; Burghoff, O.; Held, H.

    2012-03-01

    Analyzing insurance-loss data we derive stochastic storm-damage functions for residential buildings. On district level we fit power-law relations between daily loss and maximum wind speed, typically spanning more than 4 orders of magnitude. The estimated exponents for 439 German districts roughly range from 8 to 12. In addition, we find correlations among the parameters and socio-demographic data, which we employ in a simplified parametrization of the damage function with just 3 independent parameters for each district. A Monte Carlo method is used to generate loss estimates and confidence bounds of daily and annual storm damages in Germany. Our approach reproduces the annual progression of winter storm losses and enables to estimate daily losses over a wide range of magnitudes.

  10. Estimating Power Outage Cost based on a Survey for Industrial Customers

    NASA Astrophysics Data System (ADS)

    Yoshida, Yoshikuni; Matsuhashi, Ryuji

    A survey was conducted on power outage cost for industrial customers. 5139 factories, which are designated energy management factories in Japan, answered their power consumption and the loss of production value due to the power outage in an hour in summer weekday. The median of unit cost of power outage of whole sectors is estimated as 672 yen/kWh. The sector of services for amusement and hobbies and the sector of manufacture of information and communication electronics equipment relatively have higher unit cost of power outage. Direct damage cost from power outage in whole sectors reaches 77 billion yen. Then utilizing input-output analysis, we estimated indirect damage cost that is caused by the repercussion of production halt. Indirect damage cost in whole sectors reaches 91 billion yen. The sector of wholesale and retail trade has the largest direct damage cost. The sector of manufacture of transportation equipment has the largest indirect damage cost.

  11. Estimation of vulnerability functions based on a global earthquake damage database

    NASA Astrophysics Data System (ADS)

    Spence, R. J. S.; Coburn, A. W.; Ruffle, S. J.

    2009-04-01

    Developing a better approach to the estimation of future earthquake losses, and in particular to the understanding of the inherent uncertainties in loss models, is vital to confidence in modelling potential losses in insurance or for mitigation. For most areas of the world there is currently insufficient knowledge of the current building stock for vulnerability estimates to be based on calculations of structural performance. In such areas, the most reliable basis for estimating vulnerability is performance of the building stock in past earthquakes, using damage databases, and comparison with consistent estimates of ground motion. This paper will present a new approach to the estimation of vulnerabilities using the recently launched Cambridge University Damage Database (CUEDD). CUEDD is based on data assembled by the Martin Centre at Cambridge University since 1980, complemented by other more-recently published and some unpublished data. The database assembles in a single, organised, expandable and web-accessible database, summary information on worldwide post-earthquake building damage surveys which have been carried out since the 1960's. Currently it contains data on the performance of more than 750,000 individual buildings, in 200 surveys following 40 separate earthquakes. The database includes building typologies, damage levels, location of each survey. It is mounted on a GIS mapping system and links to the USGS Shakemaps of each earthquake which enables the macroseismic intensity and other ground motion parameters to be defined for each survey and location. Fields of data for each building damage survey include: · Basic earthquake data and its sources · Details of the survey location and intensity and other ground motion observations or assignments at that location · Building and damage level classification, and tabulated damage survey results · Photos showing typical examples of damage. In future planned extensions of the database information on human casualties will also be assembled. The database also contains analytical tools enabling data from similar locations, building classes or ground motion levels to be assembled and thus vulnerability relationships derived for any chosen ground motion parameter, for a given class of building, and for particular countries or regions. The paper presents examples of vulnerability relationships for particular classes of buildings and regions of the world, together with the estimated uncertainty ranges. It will discuss the applicability of such vulnerability functions in earthquake loss assessment for insurance purposes or for earthquake risk mitigation.

  12. Expected radiation damage of reverse-type APDs for the Astro-H mission

    NASA Astrophysics Data System (ADS)

    Kataoka, J.; Saito, T.; Yoshino, M.; Mizoma, H.; Nakamori, T.; Yatsu, Y.; Ishikawa, Y.; Matsunaga, Y.; Tajima, H.; Kokubun, M.; Edwards, P. G.

    2012-06-01

    Scheduled for launch in 2014, Astro-H is the sixth Japanese X-ray astronomy satellite mission. More than 60 silicon avalanche photodiodes (Si-APDs; hereafter APDs) will be used to read out BGO scintillators, which are implemented to generate a veto signal to reduce background contamination for the hard X-ray imager (HXI) and a soft gamma-ray detector (SGD). To date, however, APDs have rarely been used in space experiments. Moreover, strict environmental tests are necessary to guarantee APD performance for missions expected to extend beyond five years. The radiation hardness of APDs, as for most semiconductors, is particularly crucial, since radiation in the space environment is severe. In this paper, we present the results of radiation tests conducted on reverse-type APDs (provided by Hamamatsu Photonics) irradiated by gamma rays (60Co) and 150 MeV protons. We show that, even under the same 100 Gy dose, high energy protons can cause displacement (bulk) damage in the depletion region and possibly change the activation energy, whereas gamma-ray irradiation is less prone to cause damage, because ionization damage dominates only the surface region. We also present quantitative guidance on how to estimate APD noise deterioration over a range of temperatures and radiation doses. As a practical example, we discuss the expected degradation of the BGO energy threshold for the generation of veto signals, following several years of Astro-H operation in Low Earth Orbit (LEO), and directly compare it to experimental results obtained using a small BGO crystal.

  13. Nematode Damage Functions: The Problems of Experimental and Sampling Error

    PubMed Central

    Ferris, H.

    1984-01-01

    The development and use of pest damage functions involves measurement and experimental errors associated with cultural, environmental, and distributional factors. Damage predictions are more valuable if considered with associated probability. Collapsing population densities into a geometric series of population classes allows a pseudo-replication removal of experimental and sampling error in damage function development. Recognition of the nature of sampling error for aggregated populations allows assessment of probability associated with the population estimate. The product of the probabilities incorporated in the damage function and in the population estimate provides a basis for risk analysis of the yield loss prediction and the ensuing management decision. PMID:19295865

  14. Which leaf mechanical traits correlate with insect herbivory among feeding guilds?

    PubMed Central

    Caldwell, Elizabeth; Read, Jennifer; Sanson, Gordon D.

    2016-01-01

    Background and Aims There is abundant evidence that leaf mechanical traits deter feeding by insect herbivores, but little is known about which particular traits contribute to defence across feeding guilds. We investigated the contribution of multiple mechanical traits from shear, punch and tear tests to herbivore deterrence across feeding guilds. Methods Visible damage from miners and external chewers was measured and sucker feeding density estimated in mature leaves of 20 species of forest shrubs and small trees. Cafeteria trials were undertaken using a generalist chewer (larvae of Epiphyas postvittana, Lepidoptera). Damage was compared with leaf mechanical traits and associated nutrient and chemical defence traits. Key Results Damage by external chewers in the field and by E. postvittana correlated negatively with mechanical traits. Hierarchical partitioning analysis indicated that the strongest independent contribution to chewing damage was by the material trait of specific work to shear, with 68 % of total variance explained by the combination of specific work to shear (alone explaining 54 %) and tannin activity in a regression model. Mining damage did not correlate with mechanical traits, probably because miners can avoid tissues that generate high strength and toughness in mature leaves. Mechanical traits correlated more strongly with chewing damage in the field than chemical defences (total phenolics and tannin activity) and nutrients (nitrogen and water), but nutrients correlated strongly with diet selection in the cafeteria trial. Surprisingly, sucker feeding density correlated positively with mechanical traits and negatively with nutrients. Conclusions Mechanical traits of mature leaves influenced insect feeding guilds differentially, reflecting differences in life history and feeding modes. For external chewers, energy (work) to fracture in shearing tests, at both structural and material levels, was strongly predictive of damage. Knowing which leaf mechanical traits influence insect feeding, and in which guilds, is important to our wider understanding of plant–herbivore interactions. PMID:26715468

  15. VULNERABILITY TO HURRICANE DAMAGE ON THE U.S. GULF COAST SINCE 1950

    PubMed Central

    LOGAN, JOHN R.; XU, ZENGWANG

    2015-01-01

    We study hurricane risk on the U.S. Gulf Coast during 1950–2005, estimating the wind damage and storm surge from every hurricane in this extended period. Wind damage is estimated from the known path and wind speeds of individual storms and calibrated to fit actual damage reports for a sample of Gulf Coast storms. Storm surge is estimated using the SLOSH model developed by NOAA. These models provide the first comprehensive overview of the hurricane storm hazard as it has been experienced over a fifty-six-year period. We link the estimated damage with information on the population and specific socio-demographic components of the population (by age, race, and poverty status). Results show that white, young adult, and nonpoor populations have shifted over time away from zones with higher risk of wind damage, while more vulnerable population groups–the elderly, African Americans, and poor—have moved in the opposite direction. All groups have moved away from areas with high risk of storm surge since 1970. But in this case, perhaps because living near the water is still perceived as an amenity, those at highest risk are whites, elderly, and nonpoor households. Here exposure represents a trade-off between the risk and the amenity. PMID:25926706

  16. The evaluation of distributed damage in concrete based on sinusoidal modeling of the ultrasonic response.

    PubMed

    Sepehrinezhad, Alireza; Toufigh, Vahab

    2018-05-25

    Ultrasonic wave attenuation is an effective descriptor of distributed damage in inhomogeneous materials. Methods developed to measure wave attenuation have the potential to provide an in-site evaluation of existing concrete structures insofar as they are accurate and time-efficient. In this study, material classification and distributed damage evaluation were investigated based on the sinusoidal modeling of the response from the through-transmission ultrasonic tests on polymer concrete specimens. The response signal was modeled as single or the sum of damping sinusoids. Due to the inhomogeneous nature of concrete materials, model parameters may vary from one specimen to another. Therefore, these parameters are not known in advance and should be estimated while the response signal is being received. The modeling procedure used in this study involves a data-adaptive algorithm to estimate the parameters online. Data-adaptive algorithms are used due to a lack of knowledge of the model parameters. The damping factor was estimated as a descriptor of the distributed damage. The results were compared in two different cases as follows: (1) constant excitation frequency with varying concrete mixtures and (2) constant mixture with varying excitation frequencies. The specimens were also loaded up to their ultimate compressive strength to investigate the effect of distributed damage in the response signal. The results of the estimation indicated that the damping was highly sensitive to the change in material inhomogeneity, even in comparable mixtures. In addition to the proposed method, three methods were employed to compare the results based on their accuracy in the classification of materials and the evaluation of the distributed damage. It is shown that the estimated damping factor is not only sensitive to damage in the final stages of loading, but it is also applicable in evaluating micro damages in the earlier stages providing a reliable descriptor of damage. In addition, the modified amplitude ratio method is introduced as an improvement of the classical method. The proposed methods were validated to be effective descriptors of distributed damage. The presented models were also in good agreement with the experimental data. Copyright © 2018 Elsevier B.V. All rights reserved.

  17. Damage assessment in composite laminates via broadband Lamb wave.

    PubMed

    Gao, Fei; Zeng, Liang; Lin, Jing; Shao, Yongsheng

    2018-05-01

    Time of flight (ToF) based method for damage detection using Lamb waves is widely used. However, due to the energy dissipation of Lamb waves and the non-ignorable size of damage in composite structure, the performance of damage detection is restricted. The objective of this research is to establish an improved method to locate and assess damages in composite structure. To choose appropriate excitation parameters, the propagation characters of Lamb waves in quasi-isotropic composite laminates are firstly studied and the broadband excitation is designed. Subsequently, the pulse compression technique is adopted for energy concentration and high-accuracy distance estimation. On this basis, the gravity center of intersections of path loci is employed for damage localization and the convex envelop of identified damage edge points is taken for damage contour estimation. As a result, both damage location and size can be evaluated, thereby providing the information for quantitative damage detection. The experiment consisting of five different sizes of damage is carried for method verification and the identified results show the efficiency of the proposed method. Copyright © 2018 Elsevier B.V. All rights reserved.

  18. Dependence of Early and Late Chromosomal Aberrations on Radiation Quality and Cell Types

    NASA Technical Reports Server (NTRS)

    Lu, Tao; Zhang, Ye; Krieger, Stephanie; Yeshitla, Samrawit; Goss, Rosalin; Bowler, Deborah; Kadhim, Munira; Wilson, Bobby; Rohde, Larry; Wu, Honglu

    2017-01-01

    Exposure to radiation induces different types of DNA damage, increases mutation and chromosome aberration rates, and increases cellular transformation in vitro and in vivo. The susceptibility of cells to radiation depends on genetic background and growth condition of cells, as well as types of radiation. Mammalian cells of different tissue types and with different genetic background are known to have different survival rate and different mutation rate after cytogenetic insults. Genomic instability, induced by various genetic, metabolic, and environmental factors including radiation, is the driving force of tumorigenesis. Accurate measurements of the relative biological effectiveness (RBE) is important for estimating radiation-related risks. To further understand genomic instability induced by charged particles and their RBE, we exposed human lymphocytes ex vivo, human fibroblast AG1522, human mammary epithelial cells (CH184B5F5/M10), and bone marrow cells isolated from CBA/CaH(CBA) and C57BL/6 (C57) mice to high energy protons and Fe ions. Normal human fibroblasts AG1522 have apparently normal DNA damage response and repair mechanisms, while mammary epithelial cells (M10) are deficient in the repair of DNA DSBs. Mouse strain CBA is radio-sensitive while C57 is radio-resistant. Metaphase chromosomes at different cell divisions after radiation exposure were collected and chromosome aberrations were analyzed as RBE for different cell lines exposed to different radiations at various time points up to one month post irradiation.

  19. Improving PAGER's real-time earthquake casualty and loss estimation toolkit: a challenge

    USGS Publications Warehouse

    Jaiswal, K.S.; Wald, D.J.

    2012-01-01

    We describe the on-going developments of PAGER’s loss estimation models, and discuss value-added web content that can be generated related to exposure, damage and loss outputs for a variety of PAGER users. These developments include identifying vulnerable building types in any given area, estimating earthquake-induced damage and loss statistics by building type, and developing visualization aids that help locate areas of concern for improving post-earthquake response efforts. While detailed exposure and damage information is highly useful and desirable, significant improvements are still necessary in order to improve underlying building stock and vulnerability data at a global scale. Existing efforts with the GEM’s GED4GEM and GVC consortia will help achieve some of these objectives. This will benefit PAGER especially in regions where PAGER’s empirical model is less-well constrained; there, the semi-empirical and analytical models will provide robust estimates of damage and losses. Finally, we outline some of the challenges associated with rapid casualty and loss estimation that we experienced while responding to recent large earthquakes worldwide.

  20. Cuff-Based Oscillometric Central and Brachial Blood Pressures Obtained Through ABPM are Similarly Associated with Renal Organ Damage in Arterial Hypertension.

    PubMed

    Fernández-Llama, Patricia; Pareja, Júlia; Yun, Sergi; Vázquez, Susana; Oliveras, Anna; Armario, Pedro; Blanch, Pedro; Calero, Francesca; Sierra, Cristina; de la Sierra, Alejandro

    2017-01-01

    Central blood pressure (BP) has been suggested to be a better estimator of hypertension-associated risks. We aimed to evaluate the association of 24-hour central BP, in comparison with 24-hour peripheral BP, with the presence of renal organ damage in hypertensive patients. Brachial and central (calculated by an oscillometric system through brachial pulse wave analysis) office BP and ambulatory BP monitoring (ABPM) data and aortic pulse wave velocity (PWV) were measured in 208 hypertensive patients. Renal organ damage was evaluated by means of the albumin to creatinine ratio and the estimated glomerular filtration rate. Fifty-four patients (25.9%) were affected by renal organ damage, displaying either microalbuminuria (urinary albumin excretion ≥30 mg/g creatinine) or an estimated glomerular filtration rate (eGFR) <60 ml/min/1.73 m2. Compared to those without renal abnormalities, hypertensive patients with kidney damage had higher values of office brachial systolic BP (SBP) and pulse pressure (PP), and 24-h, daytime, and nighttime central and brachial SBP and PP. They also had a blunted nocturnal decrease in both central and brachial BP, and higher values of aortic PWV. After adjustment for age, gender, and antihypertensive treatment, only ABPM-derived BP estimates (both central and brachial) showed significant associations with the presence of renal damage. Odds ratios for central BP estimates were not significantly higher than those obtained for brachial BP. Compared with peripheral ABPM, cuff-based oscillometric central ABPM does not show a closer association with presence of renal organ damage in hypertensive patients. More studies, however, need to be done to better identify the role of central BP in clinical practice. © 2017 The Author(s). Published by S. Karger AG, Basel.

  1. Diabetes Impairs the Vascular Recruitment of Normal Stem Cells by Oxidant Damage, Reversed by Increases in pAMPK, Heme Oxygenase-1, and Adiponectin

    PubMed Central

    Sambuceti, Gianmario; Morbelli, Silvia; Vanella, Luca; Kusmic, Claudia; Marini, Cecilia; Massollo, Michela; Augeri, Carla; Corselli, Mirko; Ghersi, Chiara; Chiavarina, Barbara; Rodella, Luigi F; L'Abbate, Antonio; Drummond, George; Abraham, Nader G; Frassoni, Francesco

    2009-01-01

    Background Atherosclerosis progression is accelerated in diabetes mellitus (DM) by either direct endothelial damage or reduced availability and function of endothelial progenitor cells (EPCs). Both alterations are related to increased oxidant damage. Aim We examined if DM specifically impairs vascular signaling, thereby reducing the recruitment of normal EPCs, and if increases in antioxidant levels by induction of heme oxygenase-1 (HO-1) can reverse this condition. Methods Control and diabetic rats were treated with the HO-1 inducer cobalt protoporphyrin (CoPP) once a week for 3 weeks. Eight weeks after the development of diabetes, EPCs harvested from the aorta of syngenic inbred normal rats and labeled with technetium-99m-exametazime were infused via the femoral vein to estimate their blood clearance and aortic recruitment. Circulating endothelial cells (CECs) and the aortic expression of thrombomodulin (TM), CD31, and endothelial nitric oxide synthase (eNOS) were used to measure endothelial damage. Results DM reduced blood clearance and aortic recruitment of EPCs. Both parameters were returned to control levels by CoPP treatment without affecting EPC kinetics in normal animals. These abnormalities of EPCs in DM were paralleled by reduced serum adiponectin levels, increased numbers of CECs, reduced endothelial expression of phosphorylated eNOS, and reduced levels of TM, CD31, and phosphorylated AMP-activated protein kinase (pAMPK). CoPP treatment restored all of these parameters to normal levels. Conclusion Type II DM and its related oxidant damage hamper the interaction between the vascular wall and normal EPCs by mechanisms that are, at least partially, reversed by the induction of HO-1 gene expression, adiponectin, and pAMPK levels. PMID:19038792

  2. Estimating bird damage from damage incidence in wine grape vineyards

    USGS Publications Warehouse

    DeHaven, R.W.; Hothem, R.L.

    1981-01-01

    Bird damage was measured during 1977 and 1978 at 32 wine grape vineyards in the San Joaquin Valley and North Coastal Region of California. Both the percentage bird loss (PBL) and the percentage of bunches damaged (BDI = bird damage incidence) were determined during 55 total-damage assessments, and the resulting data pairs were used to develop a regression of PBL on BDI. The final prediction equation was loge (PBL + 1) = 0.0385 BDI, for which the SE = 9.6297 10-4, and it accounted for 97% of the observed variation. We conclude that by using that equation, reasonably accurate predictions of PBL can be obtained from relatively quick and inexpensive estimates of BDI. Guidelines for the use of the prediction method and the accuracy of some PBL predictions are discussed.

  3. Economic Estimation of the Losses Caused by Surface Water Pollution Accidents in China From the Perspective of Water Bodies’ Functions

    PubMed Central

    Yao, Hong; You, Zhen; Liu, Bo

    2016-01-01

    The number of surface water pollution accidents (abbreviated as SWPAs) has increased substantially in China in recent years. Estimation of economic losses due to SWPAs has been one of the focuses in China and is mentioned many times in the Environmental Protection Law of China promulgated in 2014. From the perspective of water bodies’ functions, pollution accident damages can be divided into eight types: damage to human health, water supply suspension, fishery, recreational functions, biological diversity, environmental property loss, the accident’s origin and other indirect losses. In the valuation of damage to people’s life, the procedure for compensation of traffic accidents in China was used. The functional replacement cost method was used in economic estimation of the losses due to water supply suspension and loss of water’s recreational functions. Damage to biological diversity was estimated by recovery cost analysis and damage to environmental property losses were calculated using pollutant removal costs. As a case study, using the proposed calculation procedure the economic losses caused by the major Songhuajiang River pollution accident that happened in China in 2005 have been estimated at 2263 billion CNY. The estimated economic losses for real accidents can sometimes be influenced by social and political factors, such as data authenticity and accuracy. Besides, one or more aspects in the method might be overestimated, underrated or even ignored. The proposed procedure may be used by decision makers for the economic estimation of losses in SWPAs. Estimates of the economic losses of pollution accidents could help quantify potential costs associated with increased risk sources along lakes/rivers but more importantly, highlight the value of clean water to society as a whole. PMID:26805869

  4. Economic Estimation of the Losses Caused by Surface Water Pollution Accidents in China From the Perspective of Water Bodies' Functions.

    PubMed

    Yao, Hong; You, Zhen; Liu, Bo

    2016-01-22

    The number of surface water pollution accidents (abbreviated as SWPAs) has increased substantially in China in recent years. Estimation of economic losses due to SWPAs has been one of the focuses in China and is mentioned many times in the Environmental Protection Law of China promulgated in 2014. From the perspective of water bodies' functions, pollution accident damages can be divided into eight types: damage to human health, water supply suspension, fishery, recreational functions, biological diversity, environmental property loss, the accident's origin and other indirect losses. In the valuation of damage to people's life, the procedure for compensation of traffic accidents in China was used. The functional replacement cost method was used in economic estimation of the losses due to water supply suspension and loss of water's recreational functions. Damage to biological diversity was estimated by recovery cost analysis and damage to environmental property losses were calculated using pollutant removal costs. As a case study, using the proposed calculation procedure the economic losses caused by the major Songhuajiang River pollution accident that happened in China in 2005 have been estimated at 2263 billion CNY. The estimated economic losses for real accidents can sometimes be influenced by social and political factors, such as data authenticity and accuracy. Besides, one or more aspects in the method might be overestimated, underrated or even ignored. The proposed procedure may be used by decision makers for the economic estimation of losses in SWPAs. Estimates of the economic losses of pollution accidents could help quantify potential costs associated with increased risk sources along lakes/rivers but more importantly, highlight the value of clean water to society as a whole.

  5. Improvement of Accuracy for Background Noise Estimation Method Based on TPE-AE

    NASA Astrophysics Data System (ADS)

    Itai, Akitoshi; Yasukawa, Hiroshi

    This paper proposes a method of a background noise estimation based on the tensor product expansion with a median and a Monte carlo simulation. We have shown that a tensor product expansion with absolute error method is effective to estimate a background noise, however, a background noise might not be estimated by using conventional method properly. In this paper, it is shown that the estimate accuracy can be improved by using proposed methods.

  6. Identifying Hail Signatures in Satellite Imagery from the 9-10 August 2011 Severe Weather Event

    NASA Technical Reports Server (NTRS)

    Dryden, Rachel L.; Molthan, Andrew L.; Cole, Tony A.; Bell, Jordan

    2014-01-01

    Severe thunderstorms can produce large hail that causes property damage, livestock fatalities, and crop failure. However, detailed storm surveys of hail damage conducted by the National Weather Service (NWS) are not required. Current gaps also exist between Storm Prediction Center (SPC) hail damage estimates and crop-insurance payouts. NASA's Moderate Resolution Imaging Spectroradiometer (MODIS) instrument aboard the Terra and Aqua satellites can be used to support NWS damage assessments, particularly to crops during the growing season. The two-day severe weather event across western Nebraska and central Kansas during 9-10 August 2011 offers a case study for investigating hail damage signatures by examining changes in Normalized Difference Vegetation Index (NDVI) derived from MODIS imagery. By analyzing hail damage swaths in satellite imagery, potential economic losses due to crop damage can be quantified and further improve the estimation of weather impacts on agriculture without significantly increasing manpower requirements.

  7. Real-time earthquake shake, damage, and loss mapping for Istanbul metropolitan area

    NASA Astrophysics Data System (ADS)

    Zülfikar, A. Can; Fercan, N. Özge Zülfikar; Tunç, Süleyman; Erdik, Mustafa

    2017-01-01

    The past devastating earthquakes in densely populated urban centers, such as the 1994 Northridge; 1995 Kobe; 1999 series of Kocaeli, Düzce, and Athens; and 2011 Van-Erciş events, showed that substantial social and economic losses can be expected. Previous studies indicate that inadequate emergency response can increase the number of casualties by a maximum factor of 10, which suggests the need for research on rapid earthquake shaking damage and loss estimation. The reduction in casualties in urban areas immediately following an earthquake can be improved if the location and severity of damages can be rapidly assessed by information from rapid response systems. In this context, a research project (TUBITAK-109M734) titled "Real-time Information of Earthquake Shaking, Damage, and Losses for Target Cities of Thessaloniki and Istanbul" was conducted during 2011-2014 to establish the rapid estimation of ground motion shaking and related earthquake damages and casualties for the target cities. In the present study, application to Istanbul metropolitan area is presented. In order to fulfill this objective, earthquake hazard and risk assessment methodology known as Earthquake Loss Estimation Routine, which was developed for the Euro-Mediterranean region within the Network of Research Infrastructures for European Seismology EC-FP6 project, was used. The current application to the Istanbul metropolitan area provides real-time ground motion information obtained by strong motion stations distributed throughout the densely populated areas of the city. According to this ground motion information, building damage estimation is computed by using grid-based building inventory, and the related loss is then estimated. Through this application, the rapidly estimated information enables public and private emergency management authorities to take action and allocate and prioritize resources to minimize the casualties in urban areas during immediate post-earthquake periods. Moreover, it is expected that during an earthquake, rapid information of ground shaking, damage, and loss estimations will provide vital information to allow appropriate emergency agencies to take immediate action, which will help to save lives. In general terms, this study can be considered as an example for application to metropolitan areas under seismic risk.

  8. Muon trackers for imaging a nuclear reactor

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kume, N.; Miyadera, H.; Morris, C. L.

    A detector system for assessing damage to the cores of the Fukushima Daiichi nuclear reactors by using cosmic-ray muon tomography was developed. Furthermore, the system consists of a pair of drift-tube tracking detectors of 7.2× 7.2-m 2 area. In each muon tracker there consists 6 x-layer and 6 y-layer drift-tube detectors. Each tracker is capable of measuring muon tracks with 12 mrad angular resolutions, and is capable of operating under 50-μ Sv/h radiation environment by removing gamma induced background with a novel time-coincidence logic. An estimated resolution to observe nuclear fuel debris at Fukushima Daiichi is 0.3 m when themore » core is imaged from outside the reactor building.« less

  9. Muon trackers for imaging a nuclear reactor

    DOE PAGES

    Kume, N.; Miyadera, H.; Morris, C. L.; ...

    2016-09-21

    A detector system for assessing damage to the cores of the Fukushima Daiichi nuclear reactors by using cosmic-ray muon tomography was developed. Furthermore, the system consists of a pair of drift-tube tracking detectors of 7.2× 7.2-m 2 area. In each muon tracker there consists 6 x-layer and 6 y-layer drift-tube detectors. Each tracker is capable of measuring muon tracks with 12 mrad angular resolutions, and is capable of operating under 50-μ Sv/h radiation environment by removing gamma induced background with a novel time-coincidence logic. An estimated resolution to observe nuclear fuel debris at Fukushima Daiichi is 0.3 m when themore » core is imaged from outside the reactor building.« less

  10. [A computer tomography assisted method for the automatic detection of region of interest in dynamic kidney images].

    PubMed

    Jing, Xueping; Zheng, Xiujuan; Song, Shaoli; Liu, Kai

    2017-12-01

    Glomerular filtration rate (GFR), which can be estimated by Gates method with dynamic kidney single photon emission computed tomography (SPECT) imaging, is a key indicator of renal function. In this paper, an automatic computer tomography (CT)-assisted detection method of kidney region of interest (ROI) is proposed to achieve the objective and accurate GFR calculation. In this method, the CT coronal projection image and the enhanced SPECT synthetic image are firstly generated and registered together. Then, the kidney ROIs are delineated using a modified level set algorithm. Meanwhile, the background ROIs are also obtained based on the kidney ROIs. Finally, the value of GFR is calculated via Gates method. Comparing with the clinical data, the GFR values estimated by the proposed method were consistent with the clinical reports. This automatic method can improve the accuracy and stability of kidney ROI detection for GFR calculation, especially when the kidney function has been severely damaged.

  11. Public support for river restoration funding in relation to local river ecomorphology, population density, and mean income

    NASA Astrophysics Data System (ADS)

    SchläPfer, Felix; Witzig, Pieter-Jan

    2006-12-01

    In 1997, about 140,000 citizens in 388 voting districts in the Swiss canton of Bern passed a ballot initiative to allocate about 3 million Swiss Francs annually to a canton-wide river restoration program. Using the municipal voting returns and a detailed georeferenced data set on the ecomorphological status of the rivers, we estimate models of voter support in relation to local river ecomorphology, population density, mean income, cultural background, and recent flood damage. Support of the initiative increased with increasing population density and tended to increase with increasing mean income, in spite of progressive taxation. Furthermore, we found evidence that public support increased with decreasing "naturalness" of local rivers. The model estimates may be cautiously used to predict the public acceptance of similar restoration programs in comparable regions. Moreover, the voting-based insights into the distribution of river restoration benefits provide a useful starting point for debates about appropriate financing schemes.

  12. Stiffness degradation-based damage model for RC members and structures using fiber-beam elements

    NASA Astrophysics Data System (ADS)

    Guo, Zongming; Zhang, Yaoting; Lu, Jiezhi; Fan, Jian

    2016-12-01

    To meet the demand for an accurate and highly efficient damage model with a distinct physical meaning for performance-based earthquake engineering applications, a stiffness degradation-based damage model for reinforced concrete (RC) members and structures was developed using fiber beam-column elements. In this model, damage indices for concrete and steel fibers were defined by the degradation of the initial reloading modulus and the low-cycle fatigue law. Then, section, member, story and structure damage was evaluated by the degradation of the sectional bending stiffness, rod-end bending stiffness, story lateral stiffness and structure lateral stiffness, respectively. The damage model was realized in Matlab by reading in the outputs of OpenSees. The application of the damage model to RC columns and a RC frame indicates that the damage model is capable of accurately predicting the magnitude, position, and evolutionary process of damage, and estimating story damage more precisely than inter-story drift. Additionally, the damage model establishes a close connection between damage indices at various levels without introducing weighting coefficients or force-displacement relationships. The development of the model has perfected the damage assessment function of OpenSees, laying a solid foundation for damage estimation at various levels of a large-scale structure subjected to seismic loading.

  13. Robust Maneuvering Envelope Estimation Based on Reachability Analysis in an Optimal Control Formulation

    NASA Technical Reports Server (NTRS)

    Lombaerts, Thomas; Schuet, Stefan R.; Wheeler, Kevin; Acosta, Diana; Kaneshige, John

    2013-01-01

    This paper discusses an algorithm for estimating the safe maneuvering envelope of damaged aircraft. The algorithm performs a robust reachability analysis through an optimal control formulation while making use of time scale separation and taking into account uncertainties in the aerodynamic derivatives. Starting with an optimal control formulation, the optimization problem can be rewritten as a Hamilton- Jacobi-Bellman equation. This equation can be solved by level set methods. This approach has been applied on an aircraft example involving structural airframe damage. Monte Carlo validation tests have confirmed that this approach is successful in estimating the safe maneuvering envelope for damaged aircraft.

  14. Development of a Pulsed Pressure-Based Technique for Cavitation Damage Study

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ren, Fei; Wang, Jy-An John; Liu, Yun

    2012-01-01

    Cavitation occurs in many fluid systems and can lead to severe material damage. To assist the study of cavitation damage, a novel testing method utilizing pulsed pressure was developed. In this talk, the scientific background and the technical approach of this development are present and preliminary testing results are discussed. It is expected that this technique can be used to evaluate cavitation damage under various testing conditions including harsh environments such as those relevant to geothermal power generation.

  15. Using structural damage statistics to derive macroseismic intensity within the Kathmandu valley for the 2015 M7.8 Gorkha, Nepal earthquake

    NASA Astrophysics Data System (ADS)

    McGowan, S. M.; Jaiswal, K. S.; Wald, D. J.

    2017-09-01

    We make and analyze structural damage observations from within the Kathmandu valley following the 2015 M7.8 Gorkha, Nepal earthquake to derive macroseismic intensities at several locations including some located near ground motion recording sites. The macroseismic intensity estimates supplement the limited strong ground motion data in order to characterize the damage statistics. This augmentation allows for direct comparisons between ground motion amplitudes and structural damage characteristics and ultimately produces a more constrained ground shaking hazard map for the Gorkha earthquake. For systematic assessments, we focused on damage to three specific building categories: (a) low/mid-rise reinforced concrete frames with infill brick walls, (b) unreinforced brick masonry bearing walls with reinforced concrete slabs, and (c) unreinforced brick masonry bearing walls with partial timber framing. Evaluating dozens of photos of each construction type, assigning each building in the study sample to a European Macroseismic Scale (EMS)-98 Vulnerability Class based upon its structural characteristics, and then individually assigning an EMS-98 Damage Grade to each building allows a statistically derived estimate of macroseismic intensity for each of nine study areas in and around the Kathmandu valley. This analysis concludes that EMS-98 macroseismic intensities for the study areas from the Gorkha mainshock typically were in the VII-IX range. The intensity assignment process described is more rigorous than the informal approach of assigning intensities based upon anecdotal media or first-person accounts of felt-reports, shaking, and their interpretation of damage. Detailed EMS-98 macroseismic assessments in urban areas are critical for quantifying relations between shaking and damage as well as for calibrating loss estimates. We show that the macroseismic assignments made herein result in fatality estimates consistent with the overall and district-wide reported values.

  16. Using structural damage statistics to derive macroseismic intensity within the Kathmandu valley for the 2015 M7.8 Gorkha, Nepal earthquake

    USGS Publications Warehouse

    McGowan, Sean; Jaiswal, Kishor; Wald, David J.

    2017-01-01

    We make and analyze structural damage observations from within the Kathmandu valley following the 2015 M7.8 Gorkha, Nepal earthquake to derive macroseismic intensities at several locations including some located near ground motion recording sites. The macroseismic intensity estimates supplement the limited strong ground motion data in order to characterize the damage statistics. This augmentation allows for direct comparisons between ground motion amplitudes and structural damage characteristics and ultimately produces a more constrained ground shaking hazard map for the Gorkha earthquake. For systematic assessments, we focused on damage to three specific building categories: (a) low/mid-rise reinforced concrete frames with infill brick walls, (b) unreinforced brick masonry bearing walls with reinforced concrete slabs, and (c) unreinforced brick masonry bearing walls with partial timber framing. Evaluating dozens of photos of each construction type, assigning each building in the study sample to a European Macroseismic Scale (EMS)-98 Vulnerability Class based upon its structural characteristics, and then individually assigning an EMS-98 Damage Grade to each building allows a statistically derived estimate of macroseismic intensity for each of nine study areas in and around the Kathmandu valley. This analysis concludes that EMS-98 macroseismic intensities for the study areas from the Gorkha mainshock typically were in the VII–IX range. The intensity assignment process described is more rigorous than the informal approach of assigning intensities based upon anecdotal media or first-person accounts of felt-reports, shaking, and their interpretation of damage. Detailed EMS-98 macroseismic assessments in urban areas are critical for quantifying relations between shaking and damage as well as for calibrating loss estimates. We show that the macroseismic assignments made herein result in fatality estimates consistent with the overall and district-wide reported values.

  17. Characteristics of seismic and tsunami fragility of industries, revealed by the 2011 Tohoku-oki earthquake

    NASA Astrophysics Data System (ADS)

    Kuwahara, Y.; Hasegawa, I.; Yoshimi, M.; Namegaya, Y.; Horikawa, H.; Nakai, M.; Masuda, S.

    2013-12-01

    We have developed seismic and tsunami fragility curves of industries by using damage data of industrial companies, estimated strong motions and estimated tsunami heights of the 2011 Tohoku-oki earthquake. The damage data were obtained from 7,019 industrial companies, which responded to an inquiry survey to 30,000 companies carried out by the Regional Innovation Research Center of Tohoku University. As a damage level indicator for each company, we introduced a ratio of an economical damage of physical fixed assets excluding lands to previous balance of the physical fixed assets. The estimated strong motions of the 2011 Tohoku-oki earthquake at all the sites of the companies were from the database of the so-called QuiQuake system (Quick estimation system for earthquake maps triggered by observation records) operated by the National Institute of Advanced Industrial Science and Technology (AIST). It is noted that the estimated data were obtained by taking account of seismic local site effects and the actually observed ones. The tsunami height data at each site of the company were obtained by interpolating the confirmed data compiled by the 2011 Tohoku Earthquake Tsunami Joint Survey Group (2013). A frequency-damage level distribution for each seismic intensity is well correlated with a binominal distribution where the only parameter characterizing the distribution is an average value of the damage levels in each seismic intensity. The averaged damage levels of all the data for respective seismic intensity scales are 0.016 for SIj 5 lower, 0.042 for SIj 5 upper, 0.067 for SIj 6 lower, 0.092 for SIj 6 upper, and 0.16 for SIj 7, where SIj stands for the Japanese seismic intensity scale. The data were sorted into several classified industries and fragility curve for each classified industry is found to have a different character from each other. The tsunami fragilities are also obtained as a function of the tsunami height in the same way. The averaged damage levels of all the data for respective tsunami height are 0.051 for less than 3m, 0.23 for 0.3-1 m, 0.27 for 1-2 m, 0.43 for 2-3 m, and 0.50 for higher than 3m, respectively. These fragility curves can be useful not only to estimate economic damages for future huge earthquakes, but also to rapidly assess the damage just after earthquakes.

  18. Acoustic emission-based sensor analysis and damage classification for structural health monitoring of composite structures

    NASA Astrophysics Data System (ADS)

    Uprety, Bibhisha

    Within the aerospace industry the need to detect and locate impact events, even when no visible damage is present, is important both from the maintenance and design perspectives. This research focused on the use of Acoustic Emission (AE) based sensing technologies to identify impact events and characterize damage modes in composite structures for structural health monitoring. Six commercially available piezoelectric AE sensors were evaluated for use with impact location estimation algorithms under development at the University of Utah. Both active and passive testing were performed to estimate the time of arrival and plate wave mode velocities for impact location estimation. Four sensors were recommended for further comparative investigations. Furthermore, instrumented low-velocity impact experiments were conducted on quasi-isotropic carbon/epoxy composite laminates to initiate specific types of damage: matrix cracking, delamination and fiber breakage. AE signal responses were collected during impacting and the test panels were ultrasonically C-scanned after impact to identify the internal damage corresponding to the AE signals. Matrix cracking and delamination damage produced using more compliant test panels and larger diameter impactor were characterized by lower frequency signals while fiber breakage produced higher frequency responses. The results obtained suggest that selected characteristics of sensor response signals can be used both to determine whether damage is produced during impacting and to characterize the types of damage produced in an impacted composite structure.

  19. Thin film contamination effects on laser-induced damage of fused silica surfaces at 355 nm

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Burnham, A. K.; Cordillot, C.; Fornier, A.

    1998-07-28

    Fused silica windows were artificially contaminated to estimate the resistance of target chamber debris shields against laser damage during NIF operation. Uniform contamination thin films (1 to 5 nm thick) were prepared by sputtering various materials (Au, Al, Cu, and B 4C). The loss of transmission of the samples was first measured. They were then tested at 355 nm in air with an 8-ns Nd:YAG laser. The damage morphologies were characterized by Nomarski optical microscopy and SEM. Both theory and experiments showed that metal contamination for films as thin as 1 nm leads to a substantial loss of transmission. Themore » laser damage resistance dropped very uniformly across the entire surface (e.g. 6 J/cm 2 for 5 nm of Cu). The damage morphology characterization showed that contrary to clean silica, metal coated samples did not produce pits on the surface. B 4C coated silica, on the other hand, led to a higher density of such damage pits. A model for light absorption in the thin film was coupled with a simple heat deposition and diffusion model to perform preliminary theoretical estimates of damage thresholds. The estimates of the loss due to light absorption and reflection pointed out significant .differences between metals (e.g. Al and Au). The damage threshold predictions were in qualitative agreement with experimental measurements.« less

  20. Proton Irradiation as a Screen for Displacement-Damage Sensitivity in Bipolar Junction Transistors

    NASA Astrophysics Data System (ADS)

    Arutt, Charles N.; Warren, Kevin M.; Schrimpf, Ronald D.; Weller, Robert A.; Kauppila, Jeffrey S.; Rowe, Jason D.; Sternberg, Andrew L.; Reed, Robert A.; Ball, Dennis R.; Fleetwood, Daniel M.

    2015-12-01

    NPN and PNP bipolar junction transistors of varying sizes are irradiated with 4-MeV protons and 10-keV X-rays to determine the amount of ionization-related degradation caused by protons and calculate an improved estimate of displacement-related degradation due to protons. While different ratios of degradation produced by displacement damage and ionization effects will occur for different device technologies, this general approach, with suitable margin, can be used as a screen for sensitivity to neutron-induced displacement damage. Further calculations are performed to estimate the amount of degradation produced by 1-MeV equivalent neutron displacement damage compared to that produced by the displacement damage due to protons. The results are compared to previous work.

  1. Application of wavefield imaging to characterize scattering from artificial and impact damage in composite laminate panels

    NASA Astrophysics Data System (ADS)

    Williams, Westin B.; Michaels, Thomas E.; Michaels, Jennifer E.

    2018-04-01

    Composite materials used for aerospace applications are highly susceptible to impacts, which can result in barely visible delaminations. Reliable and fast detection of such damage is needed before structural failures occur. One approach is to use ultrasonic guided waves generated from a sparse array consisting of permanently mounted or embedded transducers for performing structural health monitoring. This array can detect introduction of damage after baseline subtraction, and also provide localization and characterization information via the minimum variance imaging algorithm. Imaging performance can vary considerably depending upon where damage is located with respect to the array; however, prior work has shown that knowledge of expected scattering can improve imaging consistency for artificial damage at various locations. In this study, anisotropic material attenuation and wave speed are estimated as a function of propagation angle using wavefield data recorded along radial lines at multiple angles with respect to an omnidirectional guided wave source. Additionally, full wavefield data are recorded before and after the introduction of artificial and impact damage so that wavefield baseline subtraction may be applied. 3-D filtering techniques are then used to reduce noise and isolate scattered waves. A model for estimating scattering of a circular defect is developed and scattering estimates for both artificial and impact damage are presented and compared.

  2. Tracking composite material damage evolution using Bayesian filtering and flash thermography data

    NASA Astrophysics Data System (ADS)

    Gregory, Elizabeth D.; Holland, Steve D.

    2016-05-01

    We propose a method for tracking the condition of a composite part using Bayesian filtering of ash thermography data over the lifetime of the part. In this demonstration, composite panels were fabricated; impacted to induce subsurface delaminations; and loaded in compression over multiple time steps, causing the delaminations to grow in size. Flash thermography data was collected between each damage event to serve as a time history of the part. The ash thermography indicated some areas of damage but provided little additional information as to the exact nature or depth of the damage. Computed tomography (CT) data was also collected after each damage event and provided a high resolution volume model of damage that acted as truth. After each cycle, the condition estimate, from the ash thermography data and the Bayesian filter, was compared to 'ground truth'. The Bayesian process builds on the lifetime history of ash thermography scans and can give better estimates of material condition as compared to the most recent scan alone, which is common practice in the aerospace industry. Bayesian inference provides probabilistic estimates of damage condition that are updated as each new set of data becomes available. The method was tested on simulated data and then on an experimental data set.

  3. Spatial Differences and Costs of Emissions at U.S. Airport Hubs.

    PubMed

    Nahlik, Matthew J; Chester, Mikhail V; Ryerson, Megan S; Fraser, Andrew M

    2016-04-19

    As local governments plan to expand airport infrastructure and build air service, monetized estimates of damages from air pollution are important for balancing environmental impacts. While it is well-known that aircraft emissions near airports directly affect nearby populations, it is less clear how the airport-specific aircraft operations and impacts result in monetized damages to human health and the environment. We model aircraft and ground support equipment emissions at major U.S. airports and estimate the monetized human health and environmental damages of near airport (within 60 miles) emissions. County-specific unit damage costs for PM, SOx, NOx, and VOCs and damage valuations for CO and CO2 are used along with aircraft emissions estimations at airports to determine impacts. We find that near-airport emissions at major U.S. airports caused a total of $1.9 billion in damages in 2013, with airports contributing between $720 thousand and $190 million each. These damages vary by airport from $1 to $9 per seat per one-way flight and costs per passenger are often greater than airport charges levied on airlines for infrastructure use. As the U.S. aviation system grows, it is possible to minimize human and environmental costs by shifting aircraft technologies and expanding service into airports where fewer impacts are likely to occur.

  4. Probabilistic Damage Characterization Using the Computationally-Efficient Bayesian Approach

    NASA Technical Reports Server (NTRS)

    Warner, James E.; Hochhalter, Jacob D.

    2016-01-01

    This work presents a computationally-ecient approach for damage determination that quanti es uncertainty in the provided diagnosis. Given strain sensor data that are polluted with measurement errors, Bayesian inference is used to estimate the location, size, and orientation of damage. This approach uses Bayes' Theorem to combine any prior knowledge an analyst may have about the nature of the damage with information provided implicitly by the strain sensor data to form a posterior probability distribution over possible damage states. The unknown damage parameters are then estimated based on samples drawn numerically from this distribution using a Markov Chain Monte Carlo (MCMC) sampling algorithm. Several modi cations are made to the traditional Bayesian inference approach to provide signi cant computational speedup. First, an ecient surrogate model is constructed using sparse grid interpolation to replace a costly nite element model that must otherwise be evaluated for each sample drawn with MCMC. Next, the standard Bayesian posterior distribution is modi ed using a weighted likelihood formulation, which is shown to improve the convergence of the sampling process. Finally, a robust MCMC algorithm, Delayed Rejection Adaptive Metropolis (DRAM), is adopted to sample the probability distribution more eciently. Numerical examples demonstrate that the proposed framework e ectively provides damage estimates with uncertainty quanti cation and can yield orders of magnitude speedup over standard Bayesian approaches.

  5. Oenanthe Javanica Extract Protects Against Experimentally Induced Ischemic Neuronal Damage via its Antioxidant Effects

    PubMed Central

    Park, Joon Ha; Cho, Jeong Hwi; Kim, In Hye; Ahn, Ji Hyeon; Lee, Jae-Chul; Chen, Bai Hui; Shin, Bich-Na; Tae, Hyun-Jin; Yoo, Ki-Yeon; Hong, SeongKweon; Kang, Il Jun; Won, Moo-Ho; Kim, Jong-Dai

    2015-01-01

    Background: Water dropwort (Oenanthe javanica) as a popular traditional medicine in Asia shows various biological properties including antioxidant activity. In this study, we firstly examined the neuroprotective effect of Oenanthe javanica extract (OJE) in the hippocampal cornus ammonis 1 region (CA1 region) of the gerbil subjected to transient cerebral ischemia. Methods: Gerbils were established by the occlusion of common carotid arteries for 5 min. The neuroprotective effect of OJE was estimated by cresyl violet staining. In addition, 4 antioxidants (copper, zinc superoxide dismutase [SOD], manganese SOD, catalase, and glutathione peroxidase) immunoreactivities were investigated by immunohistochemistry. Results: Pyramidal neurons in the CA1 region showed neuronal death at 5 days postischemia; at this point in time, all antioxidants immunoreactivities disappeared in CA1 pyramidal neurons and showed in many nonpyramidal cells. Treatment with 200 mg/kg, not 100 mg/kg, OJE protected CA1 pyramidal neurons from ischemic damage. In addition, 200 mg/kg OJE treatment increased or maintained antioxidants immunoreactivities. Especially, among the antioxidants, glutathione peroxidase immunoreactivity was effectively increased in the CA1 pyramidal neurons of the OJE-treated sham-operated and ischemia-operated groups. Conclusion: Our present results indicate that treatment with OJE can protect neurons from transient ischemic damage and that the neuroprotective effect may be closely associated with increased or maintained intracellular antioxidant enzymes by OJE. PMID:26521793

  6. Comparison of Epidermal/Dermal Damage Between the Long-Pulsed 1064 nm Nd:YAG and 755 nm Alexandrite Lasers Under Relatively High Fluence Conditions: Quantitative and Histological Assessments

    PubMed Central

    Lee, Ju Hwan; Park, So Ra; Jo, Jeong Ho; Park, Sung Yun; Seo, Young Kwon

    2014-01-01

    Abstract Objective: The purpose of this study was to compare degrees of epidermal/dermal tissue damage quantitatively and histologically after laser irradiation, to find ideal treatment conditions with relatively high fluence for skin rejuvenation. Background data: A number of recent studies have evaluated the clinical efficacy and safety of therapeutic lasers under relatively low fluence conditions. Methods: We transmitted the long-pulsed 1064 nm Nd:YAG and 755 nm Alexandrite lasers into pig skin according to different fluences and spot diameters, and estimated epidermal/dermal temperatures. Pig skin specimens were stained with hematoxylin and eosin for histological assessments. The fluence conditions comprised 26, 30, and 36 J/cm2, and the spot diameter conditions were 5, 8, and 10 mm. Pulse duration was 30 ms for all experiments. Results: Both lasers produced reliable thermal damage on the dermis without any serious epidermal injuries, under relatively high fluence conditions. The 1064 nm laser provided more active fibrous formations than the 755 nm laser, while higher risks for tissue damages simultaneously occurred. Conclusions: The ideal treatment conditions for skin rejuvenation were 8 mm diameter with 30 J/cm2 and 10 mm diameter with 26 J/cm2 for the 1064 nm laser, and 8 mm diameter with 36 J/cm2 and 10 mm diameter with 26 J/cm2 for the 755 nm laser. PMID:24992273

  7. A systematic review and meta-analysis to determine the effect of sperm DNA damage on in vitro fertilization and intracytoplasmic sperm injection outcome

    PubMed Central

    Simon, Luke; Zini, Armand; Dyachenko, Alina; Ciampi, Antonio; Carrell, Douglas T

    2017-01-01

    Sperm DNA damage is prevalent among infertile men and is known to influence natural reproduction. However, the impact of sperm DNA damage on assisted reproduction outcomes remains controversial. Here, we conducted a meta-analysis of studies on sperm DNA damage (assessed by SCSA, TUNEL, SCD, or Comet assay) and clinical pregnancy after IVF and/or ICSI treatment from MEDLINE, EMBASE, and PUBMED database searches for this analysis. We identified 41 articles (with a total of 56 studies) including 16 IVF studies, 24 ICSI studies, and 16 mixed (IVF + ICSI) studies. These studies measured DNA damage (by one of four assays: 23 SCSA, 18 TUNEL, 8 SCD, and 7 Comet) and included a total of 8068 treatment cycles (3734 IVF, 2282 ICSI, and 2052 mixed IVF + ICSI). The combined OR of 1.68 (95% CI: 1.49–1.89; P < 0.0001) indicates that sperm DNA damage affects clinical pregnancy following IVF and/or ICSI treatment. In addition, the combined OR estimates of IVF (16 estimates, OR = 1.65; 95% CI: 1.34–2.04; P < 0.0001), ICSI (24 estimates, OR = 1.31; 95% CI: 1.08–1.59; P = 0.0068), and mixed IVF + ICSI studies (16 estimates, OR = 2.37; 95% CI: 1.89–2.97; P < 0.0001) were also statistically significant. There is sufficient evidence in the existing literature suggesting that sperm DNA damage has a negative effect on clinical pregnancy following IVF and/or ICSI treatment. PMID:27345006

  8. Association of earthquakes and faults in the San Francisco Bay area using Bayesian inference

    USGS Publications Warehouse

    Wesson, R.L.; Bakun, W.H.; Perkins, D.M.

    2003-01-01

    Bayesian inference provides a method to use seismic intensity data or instrumental locations, together with geologic and seismologic data, to make quantitative estimates of the probabilities that specific past earthquakes are associated with specific faults. Probability density functions are constructed for the location of each earthquake, and these are combined with prior probabilities through Bayes' theorem to estimate the probability that an earthquake is associated with a specific fault. Results using this method are presented here for large, preinstrumental, historical earthquakes and for recent earthquakes with instrumental locations in the San Francisco Bay region. The probabilities for individual earthquakes can be summed to construct a probabilistic frequency-magnitude relationship for a fault segment. Other applications of the technique include the estimation of the probability of background earthquakes, that is, earthquakes not associated with known or considered faults, and the estimation of the fraction of the total seismic moment associated with earthquakes less than the characteristic magnitude. Results for the San Francisco Bay region suggest that potentially damaging earthquakes with magnitudes less than the characteristic magnitudes should be expected. Comparisons of earthquake locations and the surface traces of active faults as determined from geologic data show significant disparities, indicating that a complete understanding of the relationship between earthquakes and faults remains elusive.

  9. Sample EP Flow Analysis of Severely Damaged Networks

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Werley, Kenneth Alan; McCown, Andrew William

    These are slides for a presentation at the working group meeting of the WESC SREMP Software Product Integration Team on sample EP flow analysis of severely damaged networks. The following topics are covered: ERCOT EP Transmission Model; Zoomed in to Houston and Overlaying StreetAtlas; EMPACT Solve/Dispatch/Shedding Options; QACS BaseCase Power Flow Solution; 3 Substation Contingency; Gen. & Load/100 Optimal Dispatch; Dispatch Results; Shed Load for Low V; Network Damage Summary; Estimated Service Areas (Potential); Estimated Outage Areas (potential).

  10. Evaluating the effectiveness of flood damage mitigation measures by the application of Propensity Score Matching

    NASA Astrophysics Data System (ADS)

    Hudson, P.; Botzen, W. J. W.; Kreibich, H.; Bubeck, P.; Aerts, J. C. J. H.

    2014-01-01

    The employment of damage mitigation measures by individuals is an important component of integrated flood risk management. In order to promote efficient damage mitigation measures, accurate estimates of their damage mitigation potential are required. That is, for correctly assessing the damage mitigation measures' effectiveness from survey data, one needs to control for sources of bias. A biased estimate can occur if risk characteristics differ between individuals who have, or have not, implemented mitigation measures. This study removed this bias by applying an econometric evaluation technique called Propensity Score Matching to a survey of German households along along two major rivers major rivers that were flooded in 2002, 2005 and 2006. The application of this method detected substantial overestimates of mitigation measures' effectiveness if bias is not controlled for, ranging from nearly € 1700 to € 15 000 per measure. Bias-corrected effectiveness estimates of several mitigation measures show that these measures are still very effective since they prevent between € 6700-14 000 of flood damage. This study concludes with four main recommendations regarding how to better apply Propensity Score Matching in future studies, and makes several policy recommendations.

  11. Evaluating the effectiveness of flood damage mitigation measures by the application of propensity score matching

    NASA Astrophysics Data System (ADS)

    Hudson, P.; Botzen, W. J. W.; Kreibich, H.; Bubeck, P.; Aerts, J. C. J. H.

    2014-07-01

    The employment of damage mitigation measures (DMMs) by individuals is an important component of integrated flood risk management. In order to promote efficient damage mitigation measures, accurate estimates of their damage mitigation potential are required. That is, for correctly assessing the damage mitigation measures' effectiveness from survey data, one needs to control for sources of bias. A biased estimate can occur if risk characteristics differ between individuals who have, or have not, implemented mitigation measures. This study removed this bias by applying an econometric evaluation technique called propensity score matching (PSM) to a survey of German households along three major rivers that were flooded in 2002, 2005, and 2006. The application of this method detected substantial overestimates of mitigation measures' effectiveness if bias is not controlled for, ranging from nearly EUR 1700 to 15 000 per measure. Bias-corrected effectiveness estimates of several mitigation measures show that these measures are still very effective since they prevent between EUR 6700 and 14 000 of flood damage per flood event. This study concludes with four main recommendations regarding how to better apply propensity score matching in future studies, and makes several policy recommendations.

  12. Spectral and temperature-dependent infrared emissivity measurements of painted metals for improved temperature estimation during laser damage testing

    NASA Astrophysics Data System (ADS)

    Baumann, Sean M.; Keenan, Cameron; Marciniak, Michael A.; Perram, Glen P.

    2014-10-01

    A database of spectral and temperature-dependent emissivities was created for painted Al-alloy laser-damage-testing targets for the purpose of improving the uncertainty to which temperature on the front and back target surfaces may be estimated during laser-damage testing. Previous temperature estimates had been made by fitting an assumed gray-body radiance curve to the calibrated spectral radiance data collected from the back surface using a Telops Imaging Fourier Transform Spectrometer (IFTS). In this work, temperature-dependent spectral emissivity measurements of the samples were made from room temperature to 500 °C using a Surface Optics Corp. SOC-100 Hemispherical Directional Reflectometer (HDR) with Nicolet FTS. Of particular interest was a high-temperature matte-black enamel paint used to coat the rear surfaces of the Al-alloy samples. The paint had been assumed to have a spectrally flat and temperatureinvariant emissivity. However, the data collected using the HDR showed both spectral variation and temperature dependence. The uncertainty in back-surface temperature estimation during laser-damage testing made using the measured emissivities was improved from greater than +10 °C to less than +5 °C for IFTS pixels away from the laser burn-through hole, where temperatures never exceeded those used in the SOC-100 HDR measurements. At beam center, where temperatures exceeded those used in the SOC-100 HDR, uncertainty in temperature estimates grew beyond those made assuming gray-body emissivity. Accurate temperature estimations during laser-damage testing are useful in informing a predictive model for future high-energy-laser weapon applications.

  13. A tool to estimate the Fermi Large Area Telescope background for short-duration observations

    DOE PAGES

    Vasileiou, Vlasios

    2013-07-25

    Here, the proper estimation of the background is a crucial component of data analyses in astrophysics, such as source detection, temporal studies, spectroscopy, and localization. For the case of the Large Area Telescope (LAT) on board the Fermi spacecraft, approaches to estimate the background for short (≲1000 s duration) observations fail if they ignore the strong dependence of the LAT background on the continuously changing observational conditions. We present a (to be) publicly available background-estimation tool created and used by the LAT Collaboration in several analyses of Gamma Ray Bursts. This tool can accurately estimate the expected LAT background formore » any observational conditions, including, for example, observations with rapid variations of the Fermi spacecraft’s orientation occurring during automatic repointings.« less

  14. DIETARY FOLATE DEFICIENCY ENHANCES INDUCTION OF MICRONUCLEI BY ARSENIC IN MICE

    EPA Science Inventory

    Folate deficiency increases background levels of DNA damage and can enhance the genotoxicity of chemical agents. Arsenic, a known human carcinogen present in drinking water supplies around the world, induces chromosomal and DNA damage. The effect of dietary folate deficiency on...

  15. Exposure to indoor background radiation and urinary concentrations of 8-hydroxydeoxyguanosine, a marker of oxidative DNA damage.

    PubMed Central

    Sperati, A; Abeni, D D; Tagesson, C; Forastiere, F; Miceli, M; Axelson, O

    1999-01-01

    We investigated whether exposure to indoor [gamma]-radiation and radon might be associated with enough free radical formation to increase urinary concentrations of 8-hydroxydeoxyguanosine (8-OHdG), a sensitive marker of DNA damage, due to a hydroxyl radical attack at the C8 of guanine. Indoor radon and [gamma]-radiation levels were measured in 32 dwellings for 6 months by solid-state nuclear track detectors and thermoluminescent dosimeters, respectively. Urine samples for 8-OHdG determinations were obtained from 63 healthy adult subjects living in the measured dwellings. An overall tendency toward increasing levels of 8-OHdG with increasing levels of radon and [gamma]-radiation was seen in the females, presumably due to their estimated longer occupancy in the dwellings measured. Different models were considered for females, with the steepest slopes obtained for [gamma]-radiation with a coefficient of 0.500 (log nmol/l of 8-OHdG for each unit increase of [gamma]-radiation on a log scale) (p<0.01), and increasing to 0.632 (p = 0.035), but with larger variance, when radon was included in the model. In conclusion, there seems to be an effect of indoor radioactivity on the urinary excretion of 8-OHdG for females, who are estimated to have a higher occupancy in the dwellings measured than for males, for whom occupational and other agents may also influence 8-OHdG excretion. ree radicals; [gamma]-radiation; radon. PMID:10064551

  16. Measuring oxidative damage to DNA and its repair with the comet assay.

    PubMed

    Collins, Andrew R

    2014-02-01

    Single cell gel electrophoresis, or the comet assay, was devised as a sensitive method for detecting DNA strand breaks, at the level of individual cells. A simple modification, incorporating a digestion of DNA with a lesion-specific endonuclease, makes it possible to measure oxidised bases. With the inclusion of formamidopyrimidine DNA glycosylase to recognise oxidised purines, or Nth (endonuclease III) to detect oxidised pyrimidines, the comet assay has been used extensively in human biomonitoring to monitor oxidative stress, usually in peripheral blood mononuclear cells. There is evidence to suggest that the enzymic approach is more accurate than chromatographic methods, when applied to low background levels of base oxidation. However, there are potential problems of over-estimation (because the enzymes are not completely specific) or under-estimation (failure to detect lesions that are close together). Attempts have been made to improve the inter-laboratory reproducibility of the comet assay. In addition to measuring DNA damage, the assay can be used to monitor the cellular or in vitro repair of strand breaks or oxidised bases. It also has applications in assessing the antioxidant status of cells. In its various forms, the comet assay is now an invaluable tool in human biomonitoring and genotoxicity testing. This article is part of a Special Issue entitled Current methods to study reactive oxygen species - pros and cons and biophysics of membrane proteins. Guest Editor: Christine Winterbourn. Copyright © 2013 Elsevier B.V. All rights reserved.

  17. A Coupled Approach for Structural Damage Detection with Incomplete Measurements

    NASA Technical Reports Server (NTRS)

    James, George; Cao, Timothy; Kaouk, Mo; Zimmerman, David

    2013-01-01

    This historical work couples model order reduction, damage detection, dynamic residual/mode shape expansion, and damage extent estimation to overcome the incomplete measurements problem by using an appropriate undamaged structural model. A contribution of this work is the development of a process to estimate the full dynamic residuals using the columns of a spring connectivity matrix obtained by disassembling the structural stiffness matrix. Another contribution is the extension of an eigenvector filtering procedure to produce full-order mode shapes that more closely match the measured active partition of the mode shapes using a set of modified Ritz vectors. The full dynamic residuals and full mode shapes are used as inputs to the minimum rank perturbation theory to provide an estimate of damage location and extent. The issues associated with this process are also discussed as drivers of near-term development activities to understand and improve this approach.

  18. Strategically placing green infrastructure: cost-effective land conservation in the floodplain.

    PubMed

    Kousky, Carolyn; Olmstead, Sheila M; Walls, Margaret A; Macauley, Molly

    2013-04-16

    Green infrastructure approaches have attracted increased attention from local governments as a way to lower flood risk and provide an array of other environmental services. The peer-reviewed literature, however, offers few estimates of the economic impacts of such approaches at the watershed scale. We estimate the avoided flood damages and the costs of preventing development of floodplain parcels in the East River Watershed of Wisconsin's Lower Fox River Basin. Results suggest that the costs of preventing conversion of all projected floodplain development would exceed the flood damage mitigation benefits by a substantial margin. However, targeting of investments to high-benefit, low-cost parcels can reverse this equation, generating net benefits. The analysis demonstrates how any flood-prone community can use a geographic-information-based model to estimate the flood damage reduction benefits of green infrastructure, compare them to the costs, and target investments to design cost-effective nonstructural flood damage mitigation policies.

  19. ShakeCast: Automating and Improving the Use of ShakeMap for Post-Earthquake Decision- Making and Response

    NASA Astrophysics Data System (ADS)

    Lin, K.; Wald, D. J.

    2007-12-01

    ShakeCast is a freely available, post-earthquake situational awareness application that automatically retrieves earthquake shaking data from ShakeMap, compares intensity measures against users" facilities, sends notifications of potential damage to responsible parties, and generates facility damage maps and other Web-based products for emergency managers and responders. ShakeMap, a tool used to portray the extent of potentially damaging shaking following an earthquake, provides overall information regarding the affected areas. When a potentially damaging earthquake occurs, utility and other lifeline managers, emergency responders, and other critical users have an urgent need for information about the impact on their particular facilities so they can make appropriate decisions and take quick actions to ensure safety and restore system functionality. To this end, ShakeCast estimates the potential damage to a user's widely distributed facilities by comparing the complex shaking distribution with the potentially highly variable damageability of their inventory to provide a simple, hierarchical list and maps showing structures or facilities most likely impacted. All ShakeMap and ShakeCast files and products are non-propriety to simplify interfacing with existing users" response tools and to encourage user-made enhancement to the software. ShakeCast uses standard RSS and HTTP requests to communicate with the USGS Web servers that host ShakeMaps, which are widely-distributed and heavily mirrored. The RSS approach allows ShakeCast users to initiate and receive selected ShakeMap products and information on software updates. To assess facility damage estimates, ShakeCast users can combine measured or estimated ground motion parameters with damage relationships that can be pre-computed, use one of these ground motion parameters as input, and produce a multi-state discrete output of damage likelihood. Presently three common approaches are being used to provide users with an indication of damage: HAZUS-based, intensity-based, and customized damage functions. Intensity-based thresholds are for locations with poorly established damage relationships; custom damage levels are for advanced ShakeCast users such as Caltrans which produces its own set of damage functions that correspond to the specific details of each California bridge or overpass in its jurisdiction. For users whose portfolio of structures is comprised of common, standard designs, ShakeCast offers a simplified structural damage-state estimation capability adapted from the HAZUS-MH earthquake module (NIBS and FEMA, 2003). Currently the simplified fragility settings consist of 128 combinations of HAZUS model building types, construction materials, building heights, and building-code eras.

  20. Covariance of dynamic strain responses for structural damage detection

    NASA Astrophysics Data System (ADS)

    Li, X. Y.; Wang, L. X.; Law, S. S.; Nie, Z. H.

    2017-10-01

    A new approach to address the practical problems with condition evaluation/damage detection of structures is proposed based on the distinct features of a new damage index. The covariance of strain response function (CoS) is a function of modal parameters of the structure. A local stiffness reduction in structure would cause monotonous increase in the CoS. Its sensitivity matrix with respect to local damages of structure is negative and narrow-banded. The damage extent can be estimated with an approximation to the sensitivity matrix to decouple the identification equations. The CoS sensitivity can be calibrated in practice from two previous states of measurements to estimate approximately the damage extent of a structure. A seven-storey plane frame structure is numerically studied to illustrate the features of the CoS index and the proposed method. A steel circular arch in the laboratory is tested. Natural frequencies changed due to damage in the arch and the damage occurrence can be judged. However, the proposed CoS method can identify not only damage happening but also location, even damage extent without need of an analytical model. It is promising for structural condition evaluation of selected components.

  1. Performance-based methodology for assessing seismic vulnerability and capacity of buildings

    NASA Astrophysics Data System (ADS)

    Shibin, Lin; Lili, Xie; Maosheng, Gong; Ming, Li

    2010-06-01

    This paper presents a performance-based methodology for the assessment of seismic vulnerability and capacity of buildings. The vulnerability assessment methodology is based on the HAZUS methodology and the improved capacitydemand-diagram method. The spectral displacement ( S d ) of performance points on a capacity curve is used to estimate the damage level of a building. The relationship between S d and peak ground acceleration (PGA) is established, and then a new vulnerability function is expressed in terms of PGA. Furthermore, the expected value of the seismic capacity index (SCev) is provided to estimate the seismic capacity of buildings based on the probability distribution of damage levels and the corresponding seismic capacity index. The results indicate that the proposed vulnerability methodology is able to assess seismic damage of a large number of building stock directly and quickly following an earthquake. The SCev provides an effective index to measure the seismic capacity of buildings and illustrate the relationship between the seismic capacity of buildings and seismic action. The estimated result is compared with damage surveys of the cities of Dujiangyan and Jiangyou in the M8.0 Wenchuan earthquake, revealing that the methodology is acceptable for seismic risk assessment and decision making. The primary reasons for discrepancies between the estimated results and the damage surveys are discussed.

  2. Life extending control: An interdisciplinary engineering thrust

    NASA Technical Reports Server (NTRS)

    Lorenzo, Carl F.; Merrill, Walter C.

    1991-01-01

    The concept of Life Extending Control (LEC) is introduced. Possible extensions to the cyclic damage prediction approach are presented based on the identification of a model from elementary forms. Several candidate elementary forms are presented. These extensions will result in a continuous or differential form of the damage prediction model. Two possible approaches to the LEC based on the existing cyclic damage prediction method, the measured variables LEC and the estimated variables LEC, are defined. Here, damage estimates or measurements would be used directly in the LEC. A simple hydraulic actuator driven position control system example is used to illustrate the main ideas behind LEC. Results from a simple hydraulic actuator example demonstrate that overall system performance (dynamic plus life) can be maximized by accounting for component damage in the control design.

  3. Study on the spectral characteristics of the damaged rice under brown planthopper, Nilaparvata lugens

    NASA Astrophysics Data System (ADS)

    Wu, Xiuju; Cheng, Qian

    2010-11-01

    The spectra of healthy leaves and leaves damaged by the rice brown planthopper (BPH, Nilaparvata lugens) were measured using a Spectroradiometer with spectral range of 350-1050 nm and resolution of 3 nm. The data was analyzed using the method of red edge methods. In the range of 430-530 nm and 560-730cnm, the band depth and slope were calculated. The damage degrees of rice plants caused by the BPH nymphae with different numbers were measured well by the spectral reflectance. The spectral characteristics of damaged rice under brown Planthopper, Nilaparvata lugenswere analyzed, and the reflectance was significantly negatively correlated with the number of BPHs. The red edge slope and edge area of the reflectance also significance correlated with the number of nymphae. The estimation models were constructed to estimate the BPHs using the spectral reflectance at the wavelengths of 550 nm and 760 nm and the red edge index. The results showed that accuracy of the estimation models were 66-81% and the spectral reflectance at R755 was efficient for estimating the number of BPHs.

  4. Multicomponent seismic loss estimation on the North Anatolian Fault Zone (Turkey)

    NASA Astrophysics Data System (ADS)

    karimzadeh Naghshineh, S.; Askan, A.; Erberik, M. A.; Yakut, A.

    2015-12-01

    Seismic loss estimation is essential to incorporate seismic risk of structures into an efficient decision-making framework. Evaluation of seismic damage of structures requires a multidisciplinary approach including earthquake source characterization, seismological prediction of earthquake-induced ground motions, prediction of structural responses exposed to ground shaking, and finally estimation of induced damage to structures. As the study region, Erzincan, a city on the eastern part of Turkey is selected which is located in the conjunction of three active strike-slip faults as North Anatolian Fault, North East Anatolian Fault and Ovacik fault. Erzincan city center is in a pull-apart basin underlain by soft sediments that has experienced devastating earthquakes such as the 27 December 1939 (Ms=8.0) and the 13 March 1992 (Mw=6.6) events, resulting in extensive amount of physical as well as economical losses. These losses are attributed to not only the high seismicity of the area but also as a result of the seismic vulnerability of the constructed environment. This study focuses on the seismic damage estimation of Erzincan using both regional seismicity and local building information. For this purpose, first, ground motion records are selected from a set of scenario events simulated with the stochastic finite fault methodology using regional seismicity parameters. Then, existing building stock are classified into specified groups represented with equivalent single-degree-of-freedom systems. Through these models, the inelastic dynamic structural responses are investigated with non-linear time history analysis. To assess the potential seismic damage in the study area, fragility curves for the classified structural types are derived. Finally, the estimated damage is compared with the observed damage during the 1992 Erzincan earthquake. The results are observed to have a reasonable match indicating the efficiency of the ground motion simulations and building analyses.

  5. Preterm newborns show slower repair of oxidative damage and paternal smoking associated DNA damage.

    PubMed

    Vande Loock, Kim; Ciardelli, Roberta; Decordier, Ilse; Plas, Gina; Haumont, Dominique; Kirsch-Volders, Micheline

    2012-09-01

    Newborns have to cope with hypoxia during delivery and a sudden increase in oxygen at birth. Oxygen will partly be released as reactive oxygen species having the potential to cause damage to DNA and proteins. In utero, increase of most (non)-enzymatic antioxidants occurs during last weeks of gestation, making preterm neonates probably more sensitive to oxidative stress. Moreover, it has been hypothesized that oxidative stress might be the common etiological factor for certain neonatal diseases in preterm infants. The aim of this study was to assess background DNA damage; in vitro H(2)O(2) induced oxidative DNA damage and repair capacity (residual DNA damage) in peripheral blood mononucleated cells from 25 preterm newborns and their mothers. In addition, demographic data were taken into account and repair capacity of preterm was compared with full-term newborns. Multivariate linear regression analysis revealed that preterm infants from smoking fathers have higher background DNA damage levels than those from non-smoking fathers, emphasizing the risk of paternal smoking behaviour for the progeny. Significantly higher residual DNA damage found after 15-min repair in preterm children compared to their mothers and higher residual DNA damage after 2 h compared to full-term newborns suggest a slower DNA repair capacity in preterm children. In comparison with preterm infants born by caesarean delivery, preterm infants born by vaginal delivery do repair more slowly the in vitro induced oxidative DNA damage. Final impact of passive smoking and of the slower DNA repair activity of preterm infants need to be confirmed in a larger study population combining transgenerational genetic and/or epigenetic effects, antioxidant levels, genotypes, repair enzyme efficiency/levels and infant morbidity.

  6. Cancer Risk Estimates from Space Flight Estimated Using Yields of Chromosome Damage in Astronaut's Blood Lymphocytes

    NASA Technical Reports Server (NTRS)

    George, Kerry A.; Rhone, J.; Chappell, L. J.; Cucinotta, F. A.

    2011-01-01

    To date, cytogenetic damage has been assessed in blood lymphocytes from more than 30 astronauts before and after they participated in long-duration space missions of three months or more on board the International Space Station. Chromosome damage was assessed using fluorescence in situ hybridization whole chromosome analysis techniques. For all individuals, the frequency of chromosome damage measured within a month of return from space was higher than their preflight yield, and biodosimetry estimates were within the range expected from physical dosimetry. Follow up analyses have been performed on most of the astronauts at intervals ranging from around 6 months to many years after flight, and the cytogenetic effects of repeat long-duration missions have so far been assessed in four individuals. Chromosomal aberrations in peripheral blood lymphocytes have been validated as biomarkers of cancer risk and cytogenetic damage can therefore be used to characterize excess health risk incurred by individual crewmembers after their respective missions. Traditional risk assessment models are based on epidemiological data obtained on Earth in cohorts exposed predominantly to acute doses of gamma-rays, and the extrapolation to the space environment is highly problematic, involving very large uncertainties. Cytogenetic damage could play a key role in reducing uncertainty in risk estimation because it is incurred directly in the space environment, using specimens from the astronauts themselves. Relative cancer risks were estimated from the biodosimetry data using the quantitative approach derived from the European Study Group on Cytogenetic Biomarkers and Health database. Astronauts were categorized into low, medium, or high tertiles according to their yield of chromosome damage. Age adjusted tertile rankings were used to estimate cancer risk and results were compared with values obtained using traditional modeling approaches. Individual tertile rankings increased after space flight and analysis of follow up samples indicated that the tertile rankings remained in the high category for more than 50% of the individuals assessed so far. Crewmembers that shift and remain in the high category are projected to have increased life-time cancer risk.

  7. A probabilistic estimate of maximum acceleration in rock in the contiguous United States

    USGS Publications Warehouse

    Algermissen, Sylvester Theodore; Perkins, David M.

    1976-01-01

    This paper presents a probabilistic estimate of the maximum ground acceleration to be expected from earthquakes occurring in the contiguous United States. It is based primarily upon the historic seismic record which ranges from very incomplete before 1930 to moderately complete after 1960. Geologic data, primarily distribution of faults, have been employed only to a minor extent, because most such data have not been interpreted yet with earthquake hazard evaluation in mind.The map provides a preliminary estimate of the relative hazard in various parts of the country. The report provides a method for evaluating the relative importance of the many parameters and assumptions in hazard analysis. The map and methods of evaluation described reflect the current state of understanding and are intended to be useful for engineering purposes in reducing the effects of earthquakes on buildings and other structures.Studies are underway on improved methods for evaluating the relativ( earthquake hazard of different regions. Comments on this paper are invited to help guide future research and revisions of the accompanying map.The earthquake hazard in the United States has been estimated in a variety of ways since the initial effort by Ulrich (see Roberts and Ulrich, 1950). In general, the earlier maps provided an estimate of the severity of ground shaking or damage but the frequency of occurrence of the shaking or damage was not given. Ulrich's map showed the distribution of expected damage in terms of no damage (zone 0), minor damage (zone 1), moderate damage (zone 2), and major damage (zone 3). The zones were not defined further and the frequency of occurrence of damage was not suggested. Richter (1959) and Algermissen (1969) estimated the ground motion in terms of maximum Modified Mercalli intensity. Richter used the terms "occasional" and "frequent" to characterize intensity IX shaking and Algermissen included recurrence curves for various parts of the country in the paper accompanying his map.The first probabilistic hazard maps covering portions of the United States were by Milne and Davenport (1969a). Recently, Wiggins, Hirshberg and Bronowicki (1974) prepared a probabilistic map of maximum particle velocity and Modified Mercalli intensity for the entire United States. The maps are based on an analysis of the historical seismicity. In general, geological data were not incorporated into the development of the maps.

  8. The cost of karst subsidence and sinkhole collapse in the United States compared with other natural hazards

    USGS Publications Warehouse

    Weary, David J.

    2015-01-01

    Rocks with potential for karst formation are found in all 50 states. Damage due to karst subsidence and sinkhole collapse is a natural hazard of national scope. Repair of damage to buildings, highways, and other infrastructure represents a significant national cost. Sparse and incomplete data show that the average cost of karst-related damages in the United States over the last 15 years is estimated to be at least $300,000,000 per year and the actual total is probably much higher. This estimate is lower than the estimated annual costs for other natural hazards; flooding, hurricanes and cyclonic storms, tornadoes, landslides, earthquakes, or wildfires, all of which average over $1 billion per year. Very few state organizations track karst subsidence and sinkhole damage mitigation costs; none occurs at the Federal level. Many states discuss the karst hazard in their State hazard mitigation plans, but seldom include detailed reports of subsidence incidents or their mitigation costs. Most State highway departments do not differentiate karst subsidence or sinkhole collapse from other road repair costs. Amassing of these data would raise the estimated annual cost considerably. Information from insurance organizations about sinkhole damage claims and payouts is also not readily available. Currently there is no agency with a mandate for developing such data. If a more realistic estimate could be made, it would illuminate the national scope of this hazard and make comparison with costs of other natural hazards more realistic.

  9. Use of plasma creatine kinase pharmacokinetics to estimate the amount of excercise-induced muscle damage in Beagles.

    PubMed

    Chanoit, G P; Lefebvre, H P; Orcel, K; Laroute, V; Toutain, P L; Braun, J P

    2001-09-01

    To assess the effects of moderate exercise on plasma creatine kinase (CK) pharmacokinetics and to estimate exercise-induced muscle damage in dogs. 6 untrained adult Beagles. The study was divided into 3 phases. In phase 1, dogs ran for 1 hour at a speed of 9 km/h, and samples were used to determine the area under the plasma CK activity versus time curve (AUC) induced by exercise. In phases 2 and 3, pharmacokinetics of CK were calculated in dogs during exercise and at rest, respectively. Values for AUC and plasma clearance (CI) were used to estimate muscle damage. At rest, values for Cl, steady-state volume of distribution (Vdss), and mean retention time (MRT) were 0.32+/-0.02 ml/kg of body weight/min, 57+/-173 ml/kg, and 3.0+/-0.57 h, respectively. During exercise, Cl decreased significantly (0.26+/-0.03 ml/kg/min), MRT increased significantly, (4.4+/-0.97 h), and Vdss remained unchanged. Peak of plasma CK activity (151+/-58.8 U/L) was observed 3 hours after completion of exercise. Estimated equivalent amount of muscle corresponding to the quantity of CK released was 41+/-29.3 mg/kg. These results revealed that exercise had a minor effect on CK disposition and that the equivalent amount of muscle damaged by moderate exercise was negligible. This study illustrates the relevance for use of the minimally invasive and quantitative pharmacokinetic approach when estimating muscle damage.

  10. Climate change damages to Alaska public infrastructure and the economics of proactive adaptation

    PubMed Central

    Melvin, April M.; Larsen, Peter; Boehlert, Brent; Neumann, James E.; Chinowsky, Paul; Espinet, Xavier; Martinich, Jeremy; Baumann, Matthew S.; Rennels, Lisa; Bothner, Alexandra; Nicolsky, Dmitry J.; Marchenko, Sergey S.

    2017-01-01

    Climate change in the circumpolar region is causing dramatic environmental change that is increasing the vulnerability of infrastructure. We quantified the economic impacts of climate change on Alaska public infrastructure under relatively high and low climate forcing scenarios [representative concentration pathway 8.5 (RCP8.5) and RCP4.5] using an infrastructure model modified to account for unique climate impacts at northern latitudes, including near-surface permafrost thaw. Additionally, we evaluated how proactive adaptation influenced economic impacts on select infrastructure types and developed first-order estimates of potential land losses associated with coastal erosion and lengthening of the coastal ice-free season for 12 communities. Cumulative estimated expenses from climate-related damage to infrastructure without adaptation measures (hereafter damages) from 2015 to 2099 totaled $5.5 billion (2015 dollars, 3% discount) for RCP8.5 and $4.2 billion for RCP4.5, suggesting that reducing greenhouse gas emissions could lessen damages by $1.3 billion this century. The distribution of damages varied across the state, with the largest damages projected for the interior and southcentral Alaska. The largest source of damages was road flooding caused by increased precipitation followed by damages to buildings associated with near-surface permafrost thaw. Smaller damages were observed for airports, railroads, and pipelines. Proactive adaptation reduced total projected cumulative expenditures to $2.9 billion for RCP8.5 and $2.3 billion for RCP4.5. For road flooding, adaptation provided an annual savings of 80–100% across four study eras. For nearly all infrastructure types and time periods evaluated, damages and adaptation costs were larger for RCP8.5 than RCP4.5. Estimated coastal erosion losses were also larger for RCP8.5. PMID:28028223

  11. Climate change damages to Alaska public infrastructure and the economics of proactive adaptation.

    PubMed

    Melvin, April M; Larsen, Peter; Boehlert, Brent; Neumann, James E; Chinowsky, Paul; Espinet, Xavier; Martinich, Jeremy; Baumann, Matthew S; Rennels, Lisa; Bothner, Alexandra; Nicolsky, Dmitry J; Marchenko, Sergey S

    2017-01-10

    Climate change in the circumpolar region is causing dramatic environmental change that is increasing the vulnerability of infrastructure. We quantified the economic impacts of climate change on Alaska public infrastructure under relatively high and low climate forcing scenarios [representative concentration pathway 8.5 (RCP8.5) and RCP4.5] using an infrastructure model modified to account for unique climate impacts at northern latitudes, including near-surface permafrost thaw. Additionally, we evaluated how proactive adaptation influenced economic impacts on select infrastructure types and developed first-order estimates of potential land losses associated with coastal erosion and lengthening of the coastal ice-free season for 12 communities. Cumulative estimated expenses from climate-related damage to infrastructure without adaptation measures (hereafter damages) from 2015 to 2099 totaled $5.5 billion (2015 dollars, 3% discount) for RCP8.5 and $4.2 billion for RCP4.5, suggesting that reducing greenhouse gas emissions could lessen damages by $1.3 billion this century. The distribution of damages varied across the state, with the largest damages projected for the interior and southcentral Alaska. The largest source of damages was road flooding caused by increased precipitation followed by damages to buildings associated with near-surface permafrost thaw. Smaller damages were observed for airports, railroads, and pipelines. Proactive adaptation reduced total projected cumulative expenditures to $2.9 billion for RCP8.5 and $2.3 billion for RCP4.5. For road flooding, adaptation provided an annual savings of 80-100% across four study eras. For nearly all infrastructure types and time periods evaluated, damages and adaptation costs were larger for RCP8.5 than RCP4.5. Estimated coastal erosion losses were also larger for RCP8.5.

  12. Optimal Background Estimators in Single-Molecule FRET Microscopy.

    PubMed

    Preus, Søren; Hildebrandt, Lasse L; Birkedal, Victoria

    2016-09-20

    Single-molecule total internal reflection fluorescence (TIRF) microscopy constitutes an umbrella of powerful tools that facilitate direct observation of the biophysical properties, population heterogeneities, and interactions of single biomolecules without the need for ensemble synchronization. Due to the low signal/noise ratio in single-molecule TIRF microscopy experiments, it is important to determine the local background intensity, especially when the fluorescence intensity of the molecule is used quantitatively. Here we compare and evaluate the performance of different aperture-based background estimators used particularly in single-molecule Förster resonance energy transfer. We introduce the general concept of multiaperture signatures and use this technique to demonstrate how the choice of background can affect the measured fluorescence signal considerably. A new, to our knowledge, and simple background estimator is proposed, called the local statistical percentile (LSP). We show that the LSP background estimator performs as well as current background estimators at low molecular densities and significantly better in regions of high molecular densities. The LSP background estimator is thus suited for single-particle TIRF microscopy of dense biological samples in which the intensity itself is an observable of the technique. Copyright © 2016 Biophysical Society. Published by Elsevier Inc. All rights reserved.

  13. Damage identification of a reinforced concrete frame by finite element model updating using damage parameterization

    NASA Astrophysics Data System (ADS)

    Fang, Sheng-En; Perera, Ricardo; De Roeck, Guido

    2008-06-01

    This paper develops a sensitivity-based updating method to identify the damage in a tested reinforced concrete (RC) frame modeled with a two-dimensional planar finite element (FE) by minimizing the discrepancies of modal frequencies and mode shapes. In order to reduce the number of unknown variables, a bidimensional damage (element) function is proposed, resulting in a considerable improvement of the optimization performance. For damage identification, a reference FE model of the undamaged frame divided into a few damage functions is firstly obtained and then a rough identification is carried out to detect possible damage locations, which are subsequently refined with new damage functions to accurately identify the damage. From a design point of view, it would be useful to evaluate, in a simplified way, the remaining bending stiffness of cracked beam sections or segments. Hence, an RC damage model based on a static mechanism is proposed to estimate the remnant stiffness of a cracked RC beam segment. The damage model is based on the assumption that the damage effect spreads over a region and the stiffness in the segment changes linearly. Furthermore, the stiffness reduction evaluated using this damage model is compared with the FE updating result. It is shown that the proposed bidimensional damage function is useful in producing a well-conditioned optimization problem and the aforementioned damage model can be used for an approximate stiffness estimation of a cracked beam segment.

  14. High Resolution, Consistent Online Estimation of Potential Flood Damage in The Netherlands

    NASA Astrophysics Data System (ADS)

    Hoes, O.; Hut, R.; van Leeuwen, E.

    2014-12-01

    In the current age where water authorities no longer blindly design and maintain all infrastructure just to meet a certain standardized return period, accurate estimation of potential flood damage is important in decision making with regards to flood prevention measures. We identify three issues with current methods of estimating flood damages. Firstly, common practice is to assume that for a given land use type, damage is mainly dependent on inundation depth, and sometimes flow velocity. We recognize that depending on the type of land use inundation depth, velocity, flood duration, season, detour time and recovery time influences the amount of damage significantly. Secondly, setting stage-damage curves is usually left to an end user and can thus vary between different water authorities within a single country. What was needed at a national level is a common way of calculating flood damages, so different prevention measures can be fairly compared. Finally, most flood models use relatively large grid cells, usually in the order of 25 m2 or coarser. Especially in urban areas this leads to obvious errors: different land uses (shops, housing, park, are all classified as "urban" and treated equally. To tackle these issues we developed a web-based model which can be accessed via www.waterschadeschatter.nl (water schade schatter is Dutch for water damage estimator). It includes all necessary data sources to calculate the damage of any potential flood in the Netherlands. It uses different damage functions for different land use types, which the user can, but need not change. It runs on 0.25m2 grid cells. Both the datasets required and the amount of calculation needed is more than a desktop computer can handle. In order to start a calculation a user needs to upload the relevant flood information to the website. The calculation is divided over several multicore servers, after which the user will receive an email with a link to the results of his calculations. Our presentation will include a life demonstration of our online model.

  15. Thyroid nodularity and chromosome aberrations among women in areas of high background radiation in China

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wang, Z.Y.; Boice, J.D. Jr.; Wei, L.X.

    1990-03-21

    Thyroid nodularity following continuous low-dose radiation exposure in China was determined in 1,001 women aged 50-65 years who resided in areas of high background radiation (330 mR/yr) their entire lives, and in 1,005 comparison subjects exposed to normal levels of radiation (114 mR/yr). Cumulative doses to the thyroid were estimated to be of the order of 14 cGy and 5 cGy, respectively. Personal interviews and physical examinations were conducted, and measurements were made of serum thyroid hormone levels, urinary iodine concentrations, and chromosome aberrations in circulating lymphocytes. For all nodular disease, the prevalences in the high background and control areasmore » were 9.5% and 9.3%, respectively. For single nodules, the prevalences were 7.4% in the high background area and 6.6% in the control area (prevalence ratio = 1.13; 95% confidence interval = 0.82-1.55). There were no differences found in serum levels of thyroid hormones. Women in the high background region, however, had significantly lower concentrations of urinary iodine and significantly higher frequencies of stable and unstable chromosome aberrations. Increased intake of allium vegetables such as garlic and onions was associated with a decreased risk of nodular disease, which seems consistent with experimental studies suggesting that allium compounds can inhibit tumor growth and proliferation. The prevalence of mild diffuse goiter was higher in the high background radiation region, perhaps related to a low dietary intake of iodine. These data suggest that continuous exposure to low-level radiation throughout life is unlikely to appreciably increase the risk of thyroid cancer. However, such exposure may cause chromosomal damage.« less

  16. Background of Civil Defense and Current Damage Limiting Studies.

    ERIC Educational Resources Information Center

    Romm, Joseph

    A brief history of civil defense administration precedes analysis of nuclear attack conditions and the influence of protective measures. Damage limitation procedure is explained in terms of--(1) blast effects, (2) radiation doses, (3) geographical fallout distribution patterns, and (4) national shelter needs. Major concept emphasis relates to--(1)…

  17. In-Flight Observation of Gamma Ray Glows by ILDAS.

    PubMed

    Kochkin, Pavlo; van Deursen, A P J; Marisaldi, M; Ursi, A; de Boer, A I; Bardet, M; Allasia, C; Boissin, J-F; Flourens, F; Østgaard, N

    2017-12-16

    An Airbus A340 aircraft flew over Northern Australia with the In-Flight Lightning Damage Assessment System (ILDAS) installed onboard. A long-duration gamma ray emission was detected. The most intense emission was observed at 12 km altitude and lasted for 20 s. Its intensity was 20 times the background counts, and it was abruptly terminated by a distant lightning flash. In this work we reconstruct the aircraft path and event timeline. The glow-terminating flash triggered a discharge from the aircraft wing that was recorded by a video camera operating onboard. Another count rate increase was observed 6 min later and lasted for 30 s. The lightning activity as reported by ground networks in this region was analyzed. The measured spectra characteristics of the emission were estimated.

  18. In-Flight Observation of Gamma Ray Glows by ILDAS

    NASA Astrophysics Data System (ADS)

    Kochkin, Pavlo; van Deursen, A. P. J.; Marisaldi, M.; Ursi, A.; de Boer, A. I.; Bardet, M.; Allasia, C.; Boissin, J.-F.; Flourens, F.; Østgaard, N.

    2017-12-01

    An Airbus A340 aircraft flew over Northern Australia with the In-Flight Lightning Damage Assessment System (ILDAS) installed onboard. A long-duration gamma ray emission was detected. The most intense emission was observed at 12 km altitude and lasted for 20 s. Its intensity was 20 times the background counts, and it was abruptly terminated by a distant lightning flash. In this work we reconstruct the aircraft path and event timeline. The glow-terminating flash triggered a discharge from the aircraft wing that was recorded by a video camera operating onboard. Another count rate increase was observed 6 min later and lasted for 30 s. The lightning activity as reported by ground networks in this region was analyzed. The measured spectra characteristics of the emission were estimated.

  19. Meteoroids and Meteor Storms: A Threat to Spacecraft

    NASA Technical Reports Server (NTRS)

    Anderson, B. Jeffrey

    1999-01-01

    Robust system design is the best protection against meteoroid damage. Impacts by small meteoroids are common on satellite surfaces, but impacts by meteoroids large enough to damage well designed systems are very rare. Estimating the threat from the normal meteoroid environment is difficult. Estimates for the occasional "storm" are even more uncertain. Common sense precautions are in order for the 1999 Leonids, but wide-spread catastrophic damage is highly unlikely. Strong Leonid showers are also expected in 2000 and 2001, but these pose much less threat than 1999.

  20. The Effect of a Mars Mission on Chromosome Damage in the Blood Lymphocytes of Astronauts

    NASA Technical Reports Server (NTRS)

    George, Kerry A.; Durante, M.; Cucinnotta, F. A.

    2006-01-01

    The radiation environment encountered during a manned mission to Mars will lead to significant elevation of biological damage in astronauts. Here we present estimates of the increased frequencies of chromosome aberrations in the peripheral blood lymphocytes of astronauts after a hypothetical Mars mission using radiation dose estimations and lymphocyte biology. Results will incorporate previously published data on in vivo induced chromosome damage in the blood lymphocytes of crewmembers after ISS and Mir missions, along with recent findings on the time dependant decay of chromosome aberrations after space flight.

  1. Estimating shaking-induced casualties and building damage for global earthquake events: a proposed modelling approach

    USGS Publications Warehouse

    So, Emily; Spence, Robin

    2013-01-01

    Recent earthquakes such as the Haiti earthquake of 12 January 2010 and the Qinghai earthquake on 14 April 2010 have highlighted the importance of rapid estimation of casualties after the event for humanitarian response. Both of these events resulted in surprisingly high death tolls, casualties and survivors made homeless. In the Mw = 7.0 Haiti earthquake, over 200,000 people perished with more than 300,000 reported injuries and 2 million made homeless. The Mw = 6.9 earthquake in Qinghai resulted in over 2,000 deaths with a further 11,000 people with serious or moderate injuries and 100,000 people have been left homeless in this mountainous region of China. In such events relief efforts can be significantly benefitted by the availability of rapid estimation and mapping of expected casualties. This paper contributes to ongoing global efforts to estimate probable earthquake casualties very rapidly after an earthquake has taken place. The analysis uses the assembled empirical damage and casualty data in the Cambridge Earthquake Impacts Database (CEQID) and explores data by event and across events to test the relationships of building and fatality distributions to the main explanatory variables of building type, building damage level and earthquake intensity. The prototype global casualty estimation model described here uses a semi-empirical approach that estimates damage rates for different classes of buildings present in the local building stock, and then relates fatality rates to the damage rates of each class of buildings. This approach accounts for the effect of the very different types of buildings (by climatic zone, urban or rural location, culture, income level etc), on casualties. The resulting casualty parameters were tested against the overall casualty data from several historical earthquakes in CEQID; a reasonable fit was found.

  2. Estimation of Damaged Areas due to the 2010 Chile Earthquake and Tsunami Using SAR Imagery of Alos/palsar

    NASA Astrophysics Data System (ADS)

    Made, Pertiwi Jaya Ni; Miura, Fusanori; Besse Rimba, A.

    2016-06-01

    A large-scale earthquake and tsunami affect thousands of people and cause serious damages worldwide every year. Quick observation of the disaster damage is extremely important for planning effective rescue operations. In the past, acquiring damage information was limited to only field surveys or using aerial photographs. In the last decade, space-borne images were used in many disaster researches, such as tsunami damage detection. In this study, SAR data of ALOS/PALSAR satellite images were used to estimate tsunami damage in the form of inundation areas in Talcahuano, the area near the epicentre of the 2010 Chile earthquake. The image processing consisted of three stages, i.e. pre-processing, analysis processing, and post-processing. It was conducted using multi-temporal images before and after the disaster. In the analysis processing, inundation areas were extracted through the masking processing. It consisted of water masking using a high-resolution optical image of ALOS/AVNIR-2 and elevation masking which built upon the inundation height using DEM image of ASTER-GDEM. The area result was 8.77 Km2. It showed a good result and corresponded to the inundation map of Talcahuano. Future study in another area is needed in order to strengthen the estimation processing method.

  3. A new method for estimating the probable maximum hail loss of a building portfolio based on hailfall intensity determined by radar measurements

    NASA Astrophysics Data System (ADS)

    Aller, D.; Hohl, R.; Mair, F.; Schiesser, H.-H.

    2003-04-01

    Extreme hailfall can cause massive damage to building structures. For the insurance and reinsurance industry it is essential to estimate the probable maximum hail loss of their portfolio. The probable maximum loss (PML) is usually defined with a return period of 1 in 250 years. Statistical extrapolation has a number of critical points, as historical hail loss data are usually only available from some events while insurance portfolios change over the years. At the moment, footprints are derived from historical hail damage data. These footprints (mean damage patterns) are then moved over a portfolio of interest to create scenario losses. However, damage patterns of past events are based on the specific portfolio that was damaged during that event and can be considerably different from the current spread of risks. A new method for estimating the probable maximum hail loss to a building portfolio is presented. It is shown that footprints derived from historical damages are different to footprints of hail kinetic energy calculated from radar reflectivity measurements. Based on the relationship between radar-derived hail kinetic energy and hail damage to buildings, scenario losses can be calculated. A systematic motion of the hail kinetic energy footprints over the underlying portfolio creates a loss set. It is difficult to estimate the return period of losses calculated with footprints derived from historical damages being moved around. To determine the return periods of the hail kinetic energy footprints over Switzerland, 15 years of radar measurements and 53 years of agricultural hail losses are available. Based on these data, return periods of several types of hailstorms were derived for different regions in Switzerland. The loss set is combined with the return periods of the event set to obtain an exceeding frequency curve, which can be used to derive the PML.

  4. Associations between the Quality of the Residential Built Environment and Pregnancy Outcomes among Women in North Carolina

    PubMed Central

    Messer, Lynne C.; Kroeger, Gretchen L.

    2011-01-01

    Background: The built environment, a key component of environmental health, may be an important contributor to health disparities, particularly for reproductive health outcomes. Objective: In this study we investigated the relationship between seven indices of residential built environment quality and adverse reproductive outcomes for the City of Durham, North Carolina (USA). Methods: We surveyed approximately 17,000 residential tax parcels in central Durham, assessing > 50 individual variables on each. These data, collected using direct observation, were combined with tax assessor, public safety, and U.S. Census data to construct seven indices representing important domains of the residential built environment: housing damage, property disorder, security measures, tenure (owner or renter occupied), vacancy, crime count, and nuisance count. Fixed-slope random-intercept multilevel models estimated the association between the residential built environment and five adverse birth outcomes. Models were adjusted for maternal characteristics and clustered at the primary adjacency community unit, defined as the index block, plus all adjacent blocks that share any portion of a line segment (block boundary) or vertex. Results: Five built environment indices (housing damage, property disorder, tenure, vacancy, and nuisance count) were associated with each of the five outcomes in the unadjusted context: preterm birth, small for gestational age (SGA), low birth weight (LBW), continuous birth weight, and birth weight percentile for gestational age (BWPGA; sex-specific birth weight distributions for infants delivered at each gestational age using National Center for Health Statistics referent births for 2000–2004). However, some estimates were attenuated after adjustment. In models adjusted for individual-level covariates, housing damage remained statistically significantly associated with SGA, birth weight, and BWPGA. Conclusion: This work suggests a real and meaningful relationship between the quality of the residential built environment and birth outcomes, which we argue are a good measure of general community health. PMID:22138639

  5. Time Resolved Temperature Measurement of Hypervelocity Impact Generated Plasma Using a Global Optimization Method

    NASA Astrophysics Data System (ADS)

    Hew, Y. M.; Linscott, I.; Close, S.

    2015-12-01

    Meteoroids and orbital debris, collectively referred to as hypervelocity impactors, travel between 7 and 72 km/s in free space. Upon their impact onto the spacecraft, the energy conversion from kinetic to ionization/vaporization occurs within a very brief timescale and results in a small and dense expanding plasma with a very strong optical flash. The radio frequency (RF) emission produced by this plasma can potentially lead to electrical anomalies within the spacecraft. In addition, space weather, such as solar activity and background plasma, can establish spacecraft conditions which can exaggerate the damages done by these impacts. During the impact, a very strong impact flash will be generated. Through the studying of this emission spectrum of the impact, we hope to study the impact generated gas cloud/plasma properties. The impact flash emitted from a ground-based hypervelocity impact test is long expected by many scientists to contain the characteristics of the impact generated plasma, such as plasma temperature and density. This paper presents a method for the time-resolved plasma temperature estimation using three-color visible band photometry data with a global pattern search optimization method. The equilibrium temperature of the plasma can be estimated using an optical model which accounts for both the line emission and continuum emission from the plasma. Using a global pattern search based optimizer, the model can isolate the contribution of the continuum emission versus the line emission from the plasma. The plasma temperature can thus be estimated. Prior to the optimization step, a Gaussian process is also applied to extract the optical emission signal out of the noisy background. The resultant temperature and line-to-continuum emission weighting factor are consistent with the spectrum of the impactor material and current literature.

  6. PHYSICAL AND ECONOMIC DAMAGE FUNCTIONS FOR AIR POLLUTANTS BY RECEPTOR

    EPA Science Inventory

    This study is primarily concerned with evaluating regional economic damages to human health, material, and vegetation and of property soiling resulting from air pollution. This study represents a step forward in methodological development of air pollution damage estimation. It at...

  7. Protein carbonyl: An oxidative stress marker in gingival crevicular fluid in healthy, gingivitis, and chronic periodontitis subjects

    PubMed Central

    Pradeep, Avani R.; Ramchandraprasad, M. V.; Bajaj, Pavan; Rao, Nishanth S.; Agarwal, Esha

    2013-01-01

    Background: A defined role for reactive oxygen species (ROS) in the tissue destruction that characterizes periodontitis has been described. Protein carbonyl (PC) is the most widely used biomarker for oxidative damage to proteins, and reflects cellular damage induced by multiple forms of ROS. The purpose of this study is to determine the presence of PC in gingival crevicular fluid (GCF) in healthy, gingivitis, and chronic periodontitis (CP) subjects and to find an association, if any. Materials and Methods: A total number of 75 subjects (38 males and 37 females) were selected based on their clinical parameters into three groups: Group 1 (25 healthy subjects), Group 2 (25 gingivitis subjects), and Group 3 (25 CP subjects). GCF samples were collected to estimate the levels of PC. Results: The PC concentration in GCF was highest in subjects with CP as compared to gingivitis and healthy subjects and a significant association was observed between GCF PC levels and all periodontal parameters. Conclusion: There was an increase in PC levels in GCF as the disease process progressed from healthy to gingivitis and CP, suggesting a role for increased oxidative stress in CP. PMID:23853448

  8. Association of Radon Background and Total Background Ionizing Radiation with Alzheimer's Disease Deaths in U.S. States.

    PubMed

    Lehrer, Steven; Rheinstein, Peter H; Rosenzweig, Kenneth E

    2017-01-01

    Exposure of the brain to ionizing radiation might promote the development of Alzheimer's disease (AD). Analysis of AD death rates versus radon background radiation and total background radiation in U.S. states. Total background, radon background, cosmic and terrestrial background radiation measurements are from Assessment of Variations in Radiation Exposure in the United States and Report No. 160 - Ionizing Radiation Exposure of the Population of the United States. 2013 AD death rates by U.S. state are from the Alzheimer's Association. Radon background ionizing radiation was significantly correlated with AD death rate in 50 states and the District of Columbia (r = 0.467, p = 0.001). Total background ionizing radiation was also significantly correlated with AD death rate in 50 states and the District of Columbia (r = 0.452, p = 0.001). Multivariate linear regression weighted by state population demonstrated that AD death rate was significantly correlated with radon background (β= 0.169, p < 0.001), age (β= 0.231, p < 0.001), hypertension (β= 0.155, p < 0.001), and diabetes (β= 0.353, p < 0.001). Our findings, like other studies, suggest that ionizing radiation is a risk factor for AD. Intranasal inhalation of radon gas could subject the rhinencephalon and hippocampus to damaging radiation that initiates AD. The damage would accumulate over time, causing age to be a powerful risk factor.

  9. On the Use of Sibiling Data to Estimate the Effects of Family Background, Cognitive Skills, and Schooling: Results from the Kalamazoo Brothers Study. Discussion Papers 374-76.

    ERIC Educational Resources Information Center

    Olneck, Michael R.

    Sibling data drawn from the Kalamazoo Brothers sample are used in this report to assess the adequacy of conventional sociological variables for measuring family background, to estimate the overall effects of family background on test scores, education, occupational status, and earning, and to control family background when estimating the effects…

  10. Kinetic Damage from Meteorites

    NASA Technical Reports Server (NTRS)

    Cooke, William; Brown, Peter; Matney, Mark

    2017-01-01

    A Near Earth object impacting into Earth's atmosphere may produce damaging effects at the surface due to airblast, thermal pulse, or kinetic impact in the form of meteorites. At large sizes (>many tens of meters), the damage is amplified by the hypersonic impact of these large projectiles moving with cosmic velocity, leaving explosively produced craters. However, much more common is simple "kinetic" damage caused by the impact of smaller meteorites moving at terminal speeds. As of this date a handful of instances are definitively known of people or structures being directly hit and/or damaged by the kinetic impact of meteorites. Meteorites known to have struck humans include the Sylacauga, Alabama fall (1954) and the Mbale meteorite fall (1992). Much more common is kinetic meteorite damage to cars, buildings, and even a post box (Claxton, Georgia - 1984). Historical accounts indicate that direct kinetic damage by meteorites may be more common than recent accounts suggest (Yau et al., 1994). In this talk we will examine the contemporary meteorite flux and estimate the frequency of kinetic damage to various structures, as well as how the meteorite flux might affect the rate of human casualties. This will update an earlier study by Halliday et al (1985), adding variations expected in meteorite flux with latitude (Le Feuvre and Wieczorek, 2008) and validating these model predictions of speed and entry angle with observations from the NASA and SOMN fireball networks. In particular, we explore the physical characteristics of bright meteors which may be used as a diagnostic for estimating which fireballs produce meteorites and hence how early warning of such kinetic damage may be estimated in advance through observations and modelling.

  11. Kinetic Damage from Meteorites

    NASA Technical Reports Server (NTRS)

    Cooke, William; Brown, Peter; Matney, Mark

    2017-01-01

    A Near Earth object impacting into Earth's atmosphere may produce damaging effects at the surface due to airblast, thermal pulse, or kinetic impact in the form of meteorites. At large sizes (greater than many tens of meters), the damage is amplified by the hypersonic impact of these large projectiles moving with cosmic velocity, leaving explosively produced craters. However, much more common is simple "kinetic" damage caused by the impact of smaller meteorites moving at terminal speeds. As of this date a handful of instances are definitively known of people or structures being directly hit and/or damaged by the kinetic impact of meteorites. Meteorites known to have struck humans include the Sylacauga, Alabama fall (1954) and the Mbale meteorite fall (1992). Much more common is kinetic meteorite damage to cars, buildings, and even a post box (Claxton, Georgia - 1984). Historical accounts indicate that direct kinetic damage by meteorites may be more common than recent accounts suggest (Yau et al., 1994). In this talk we will examine the contemporary meteorite flux and estimate the frequency of kinetic damage to various structures, as well as how the meteorite flux might affect the rate of human casualties. This will update an earlier study by Halliday et al (1985), adding variations expected in meteorite flux with latitude (Le Feuvre and Wieczorek, 2008) and validating these model predictions of speed and entry angle with observations from the NASA and SOMN fireball networks. In particular, we explore the physical characteristics of bright meteors which may be used as a diagnostic for estimating which fireballs produce meteorites and hence how early warning of such kinetic damage may be estimated in advance through observations and modeling.

  12. The characteristic of the earthquake damage in Kyoto during the historical period

    NASA Astrophysics Data System (ADS)

    Nishiyama, Akihito

    2017-04-01

    The Kyoto city is located in the northern part of the Kyoto basin, central Japan and has a history of more than 1200 years. Kyoto has long been populated area with many buildings, and the center of politics, economics and culture of Japan. Due to historical large earthquakes, the Kyoto city was severely damaged such as collapses of buildings and human casualties. In the historical period, the Kyoto city has experienced six damaging large earthquake of 976, 1185, 1449, 1596, 1662 and 1830. Among them, Kyoto has experienced three damaging large earthquakes from the end of the 16th century to the middle of the 19th century, when the urban area was being expanded. All of these earthquakes are considered to be not the earthquakes in the Kyoto basin but inland earthquakes occurred in the surrounding area. The earthquake damage in Kyoto during the historical period is strongly controlled by ground conditions and earthquakes resistance of buildings rather than distance from the estimated source fault. To better estimate seismic intensity based on building damage, it is necessary to consider the state of buildings (e.g., elapsed years since established, histories of repairs and/or reinforcements, building structures) as well as the strength of ground shakings. By considering the strength of buildings at the time of an earthquake occurrence, the seismic intensity distribution due to historical large earthquakes can be estimated with higher reliability than before. The estimated seismic intensity distribution map for such historical earthquakes can be utilized for developing the strong ground motion prediction in the Kyoto basin.

  13. Climate change impacts on flood risk and asset damages within mapped 100-year floodplains of the contiguous United States

    NASA Astrophysics Data System (ADS)

    Wobus, Cameron; Gutmann, Ethan; Jones, Russell; Rissing, Matthew; Mizukami, Naoki; Lorie, Mark; Mahoney, Hardee; Wood, Andrew W.; Mills, David; Martinich, Jeremy

    2017-12-01

    A growing body of work suggests that the extreme weather events that drive inland flooding are likely to increase in frequency and magnitude in a warming climate, thus potentially increasing flood damages in the future. We use hydrologic projections based on the Coupled Model Intercomparison Project Phase 5 (CMIP5) to estimate changes in the frequency of modeled 1 % annual exceedance probability (1 % AEP, or 100-year) flood events at 57 116 stream reaches across the contiguous United States (CONUS). We link these flood projections to a database of assets within mapped flood hazard zones to model changes in inland flooding damages throughout the CONUS over the remainder of the 21st century. Our model generates early 21st century flood damages that reasonably approximate the range of historical observations and trajectories of future damages that vary substantially depending on the greenhouse gas (GHG) emissions pathway. The difference in modeled flood damages between higher and lower emissions pathways approaches USD 4 billion per year by 2100 (in undiscounted 2014 dollars), suggesting that aggressive GHG emissions reductions could generate significant monetary benefits over the long term in terms of reduced flood damages. Although the downscaled hydrologic data we used have been applied to flood impacts studies elsewhere, this research expands on earlier work to quantify changes in flood risk by linking future flood exposure to assets and damages on a national scale. Our approach relies on a series of simplifications that could ultimately affect damage estimates (e.g., use of statistical downscaling, reliance on a nationwide hydrologic model, and linking damage estimates only to 1 % AEP floods). Although future work is needed to test the sensitivity of our results to these methodological choices, our results indicate that monetary damages from inland flooding could be significantly reduced through substantial GHG mitigation.

  14. Damage localization and quantification of composite stratified beam Structures using residual force method

    NASA Astrophysics Data System (ADS)

    Behtani, A.; Bouazzouni, A.; Khatir, S.; Tiachacht, S.; Zhou, Y.-L.; Abdel Wahab, M.

    2017-05-01

    In this paper, the problem of using measured modal parameters to detect and locate damage in beam composite stratified structures with four layers of graphite/epoxy [0°/902°/0°] is investigated. A technique based on the residual force method is applied to composite stratified structure with different boundary conditions, the results of damage detection for several damage cases demonstrate that using residual force method as damage index, the damage location can be identified correctly and the damage extents can be estimated as well.

  15. Formation of Clustered DNA Damage after High-LET Irradiation: A Review

    NASA Technical Reports Server (NTRS)

    Hada, Megumi; Georgakilas, Alexandros G.

    2008-01-01

    Radiation can cause as well as cure cancer. The risk of developing radiation-induced cancer has traditionally been estimated from cancer incidence among survivors of the atomic bombs in Hiroshima and Nagasaki. These data provide the best estimate of human cancer risk over the dose range for low linear energy transfer (LET) radiations, such as X- or gamma-rays. The situation of estimating the real biological effects becomes even more difficult in the case of high LET particles encountered in space or as the result of domestic exposure to particles from radon gas emitters or other radioactive emitters like uranium-238. Complex DNA damage, i.e., the signature of high-LET radiations comprises by closely spaced DNA lesions forming a cluster of DNA damage. The two basic groups of complex DNA damage are double strand breaks (DSBs) and non-DSB oxidative clustered DNA lesions (OCDL). Theoretical analysis and experimental evidence suggest there is increased complexity and severity of complex DNA damage with increasing LET (linear energy transfer) and a high mutagenic or carcinogenic potential. Data available on the formation of clustered DNA damage (DSBs and OCDL) by high-LET radiations are often controversial suggesting a variable response to dose and type of radiation. The chemical nature and cellular repair mechanisms of complex DNA damage have been much less characterized than those of isolated DNA lesions like an oxidized base or a single strand break especially in the case of high-LET radiation. This review will focus on the induction of clustered DNA damage by high-LET radiations presenting the earlier and recent relative data.

  16. Comparison of the sand liquefaction estimated based on codes and practical earthquake damage phenomena

    NASA Astrophysics Data System (ADS)

    Fang, Yi; Huang, Yahong

    2017-12-01

    Conducting sand liquefaction estimated based on codes is the important content of the geotechnical design. However, the result, sometimes, fails to conform to the practical earthquake damages. Based on the damage of Tangshan earthquake and engineering geological conditions, three typical sites are chosen. Moreover, the sand liquefaction probability was evaluated on the three sites by using the method in the Code for Seismic Design of Buildings and the results were compared with the sand liquefaction phenomenon in the earthquake. The result shows that the difference between sand liquefaction estimated based on codes and the practical earthquake damage is mainly attributed to the following two aspects: The primary reasons include disparity between seismic fortification intensity and practical seismic oscillation, changes of groundwater level, thickness of overlying non-liquefied soil layer, local site effect and personal error. Meanwhile, although the judgment methods in the codes exhibit certain universality, they are another reason causing the above difference due to the limitation of basic data and the qualitative anomaly of the judgment formulas.

  17. An Experimental Investigation of Damage Resistances and Damage Tolerance of Composite Materials

    NASA Technical Reports Server (NTRS)

    Prabhakaran, R.

    2003-01-01

    The project included three lines of investigation, aimed at a better understanding of the damage resistance and damage tolerance of pultruded composites. The three lines of investigation were: (i) measurement of permanent dent depth after transverse indentation at different load levels, and correlation with other damage parameters such as damage area (from x-radiography) and back surface crack length, (ii) estimation of point stress and average stress characteristic dimensions corresponding to measured damage parameters, and (iii) an attempt to measure the damage area by a reflection photoelastic technique. All the three lines of investigation were pursued.

  18. Estimating monetary damages from flooding in the United States under a changing climate

    EPA Science Inventory

    A national-scale analysis of potential changes in monetary damages from flooding under climate change. The approach uses empirically based statistical relationships between historical precipitation and flood damage records from 18 hydrologic regions of the United States, along w...

  19. Comparing multistate expected damages, option price and cumulative prospect measures for valuing flood protection

    NASA Astrophysics Data System (ADS)

    Farrow, Scott; Scott, Michael

    2013-05-01

    Floods are risky events ranging from small to catastrophic. Although expected flood damages are frequently used for economic policy analysis, alternative measures such as option price (OP) and cumulative prospect value exist. The empirical magnitude of these measures whose theoretical preference is ambiguous is investigated using case study data from Baltimore City. The outcome for the base case OP measure increases mean willingness to pay over the expected damage value by about 3%, a value which is increased with greater risk aversion, reduced by increased wealth, and only slightly altered by higher limits of integration. The base measure based on cumulative prospect theory is about 46% less than expected damages with estimates declining when alternative parameters are used. The method of aggregation is shown to be important in the cumulative prospect case which can lead to an estimate up to 41% larger than expected damages. Expected damages remain a plausible and the most easily computed measure for analysts.

  20. Applicability of the comet assay in evaluation of DNA damage in healthcare providers’ working with antineoplastic drugs: a systematic review and meta-analysis

    PubMed Central

    Zare Sakhvidi, Mohammad Javad; Hajaghazadeh, Mohammad; Mostaghaci, Mehrdad; Mehrparvar, Amir houshang; Zare Sakhvidi, Fariba; Naghshineh, Elham

    2016-01-01

    Background Unintended occupational exposure to antineoplastic drugs (ANDs) may occur in medical personnel. Some ANDs are known human carcinogens and exposure can be monitored by genotoxic biomarkers. Objective To evaluate the obstacles to obtaining conclusive results from a comet assay test to determine DNA damage among AND exposed healthcare workers. Methods We systematically reviewed studies that used alkaline comet assay to determine the magnitude and significance of DNA damage among health care workers with potential AND exposure. Fifteen studies were eligible for review and 14 studies were used in the meta-analysis. Results Under random effect assumption, the estimated standardized mean difference (SMD) in the DNA damage of health care workers was 1.93 (95% CI: 1.15–2.71, p < 0.0001). The resulting SMD was reduced to 1.756 (95% CI: 0.992–2.52, p < 0.0001) when the analysis only included nurses. In subgroup analyses based on gender and smoking, heterogeneity was observed. Only for studies reporting comet moment, I2 test results, as a measure of heterogeneity, dropped to zero. Heterogeneity analysis showed that date of study publication was a possible source of heterogeneity (B = −0.14; p < 0.0001). Conclusions A mixture of personal parameters, comet assay methodological variables, and exposure characteristics may be responsible for heterogenic data from comet assay studies and interfere with obtaining conclusive results. Lack of quantitative environmental exposure measures and variation in comet assay protocols across studies are important obstacles in generalization of results. PMID:27110842

  1. Pretreatment Blood Brain Barrier Damage and Post Treatment Intracranial Hemorrhage in Patients Receiving IV tPA

    PubMed Central

    Leigh, Richard; Jen, Shyian S.; Hillis, Argye E.; Krakauer, John W.; Barker, Peter B.

    2014-01-01

    Background and Purpose Early blood brain barrier (BBB) damage after acute ischemic stroke (AIS) has previously been qualitatively linked to subsequent intracranial hemorrhage (ICH). In this quantitative study, it was investigated whether the amount of BBB damage evident on pre-tPA MRI scans was related to the degree of post-tPA ICH in patients with AIS. Methods Analysis was performed on a database of patients with AIS provided by the STIR and VISTA Imaging Investigators. Patients with perfusion-weighted imaging (PWI) lesions >10mL and negative gradient-recalled echo (GRE) imaging prior to IV tPA were included. Post processing of the PWI source images was performed to estimate changes in BBB permeability within the perfusion deficit relative to the unaffected hemisphere. Follow-up GRE images were reviewed for evidence of ICH and divided into three groups according to ECASS criteria: no hemorrhage (NH), hemorrhagic infarction (HI), and parenchymal hematoma (PH). Results 75 patients from the database met the inclusion criteria, 28 of whom experienced ICH, of which 19 were classified as HI, and nine were classified as PH. The mean permeability (±standard deviations), expressed as an index of contrast leakage, was 17.0%±8.8 in the NH group, 19.4%±4.0 in the HI group, and 24.6%±4.5 in the PH group. Permeability was significantly correlated with ICH grade in univariate (p=0.007) and multivariate (p=0.008) linear regression modeling. Conclusions A PWI-derived index of BBB damage measured prior to IV tPA is associated with the severity of ICH after treatment in patients with AIS. PMID:24876245

  2. Image correlation nondestructive evaluation of impact damage in a glass fiber composite

    NASA Technical Reports Server (NTRS)

    Russell, Samuel S.

    1990-01-01

    Presented in viewgraph format, digital image correlation, damage in fibrous composites, and damaged coupons (cross-ply scotchply GI-Ep laminate) are outlined. It was concluded that the image correlation accuracy was 0.03 percent; strains can be processed through Tsai-Hill failure criteria to qualify the damage; the statistical data base must be generated to evaluate certainty of the damage estimate; size effects need consideration; and better numerical techniques are needed.

  3. A GIS-based methodology for the estimation of potential volcanic damage and its application to Tenerife Island, Spain

    NASA Astrophysics Data System (ADS)

    Scaini, C.; Felpeto, A.; Martí, J.; Carniel, R.

    2014-05-01

    This paper presents a GIS-based methodology to estimate damages produced by volcanic eruptions. The methodology is constituted by four parts: definition and simulation of eruptive scenarios, exposure analysis, vulnerability assessment and estimation of expected damages. Multi-hazard eruptive scenarios are defined for the Teide-Pico Viejo active volcanic complex, and simulated through the VORIS tool. The exposure analysis identifies the elements exposed to the hazard at stake and focuses on the relevant assets for the study area. The vulnerability analysis is based on previous studies on the built environment and complemented with the analysis of transportation and urban infrastructures. Damage assessment is performed associating a qualitative damage rating to each combination of hazard and vulnerability. This operation consists in a GIS-based overlap, performed for each hazardous phenomenon considered and for each element. The methodology is then automated into a GIS-based tool using an ArcGIS® program. Given the eruptive scenarios and the characteristics of the exposed elements, the tool produces expected damage maps. The tool is applied to the Icod Valley (North of Tenerife Island) which is likely to be affected by volcanic phenomena in case of eruption from both the Teide-Pico Viejo volcanic complex and North-West basaltic rift. Results are thematic maps of vulnerability and damage that can be displayed at different levels of detail, depending on the user preferences. The aim of the tool is to facilitate territorial planning and risk management in active volcanic areas.

  4. Four-year post-exposure assay of vegetation surrounding project pinstripe: demonstration of the utility of delayed damage appraisals. [Larrea divaricata, Ephedra funerea, Atriplex confertifolia

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ragsdale, H.L.; Rhoads, W.A.

    1974-01-01

    This report illustrates the feasibility of using temporally-delayed vegetation assays to determine radiation damage, by documenting the radiation damage resulting from the accidental venting of radioactive materials during Project Pinstripe, Frenchman's Flat, Nevada Test Site, in April, 1966. Evidence of desert shrub radiation damage was first observed and photographed, in April, 1968. Systematic study of the vegetation was initiated in October, 1970, and evidence of radiation damage documented over 72.9 hectares adjacent to the vent. Beta doses were estimated at 15--21 krads based on gamma exposure dose measurements. The minimum beta dose estimate was substantially greater than the theoretical lethalmore » dose for the shrub, Larrea divaricata. Radiation damage to the shrubs, Larrea divaricata, Ephedra funerea, and Atriplex confertifolia was expressed as differential bud mortality, partial death of shrub crowns with and without crown regrowth, and total shrub crown death without crown regrowth. Each of the shrub populations was statistically different from its control population with respect to the distribution of individuals among damage classes. Generally, damage patterns were similar to those observed at two previously-studied Plowshare events.« less

  5. Tropical and Extratropical Cyclone Damages under Climate Change

    NASA Astrophysics Data System (ADS)

    Ranson, M.; Kousky, C.; Ruth, M.; Jantarasami, L.; Crimmins, A.; Tarquinio, L.

    2014-12-01

    This paper provides the first quantitative synthesis of the rapidly growing literature on future tropical and extratropical cyclone losses under climate change. We estimate a probability distribution for the predicted impact of changes in global surface air temperatures on future storm damages, using an ensemble of 296 estimates of the temperature-damage relationship from twenty studies. Our analysis produces three main empirical results. First, we find strong but not conclusive support for the hypothesis that climate change will cause damages from tropical cyclones and wind storms to increase, with most models (84 and 92 percent, respectively) predicting higher future storm damages due to climate change. Second, there is substantial variation in projected changes in losses across regions. Potential changes in damages are greatest in the North Atlantic basin, where the multi-model average predicts that a 2.5°C increase in global surface air temperature would cause hurricane damages to increase by 62 percent. The ensemble predictions for Western North Pacific tropical cyclones and European wind storms (extratropical cyclones) are approximately one third of that magnitude. Finally, our analysis shows that existing models of storm damages under climate change generate a wide range of predictions, ranging from moderate decreases to very large increases in losses.

  6. Economic Impacts of Non-Native Forest Insects in the Continental United States

    PubMed Central

    Aukema, Juliann E.; Leung, Brian; Kovacs, Kent; Chivers, Corey; Britton, Kerry O.; Englin, Jeffrey; Frankel, Susan J.; Haight, Robert G.; Holmes, Thomas P.; Liebhold, Andrew M.; McCullough, Deborah G.; Von Holle, Betsy

    2011-01-01

    Reliable estimates of the impacts and costs of biological invasions are critical to developing credible management, trade and regulatory policies. Worldwide, forests and urban trees provide important ecosystem services as well as economic and social benefits, but are threatened by non-native insects. More than 450 non-native forest insects are established in the United States but estimates of broad-scale economic impacts associated with these species are largely unavailable. We developed a novel modeling approach that maximizes the use of available data, accounts for multiple sources of uncertainty, and provides cost estimates for three major feeding guilds of non-native forest insects. For each guild, we calculated the economic damages for five cost categories and we estimated the probability of future introductions of damaging pests. We found that costs are largely borne by homeowners and municipal governments. Wood- and phloem-boring insects are anticipated to cause the largest economic impacts by annually inducing nearly $1.7 billion in local government expenditures and approximately $830 million in lost residential property values. Given observations of new species, there is a 32% chance that another highly destructive borer species will invade the U.S. in the next 10 years. Our damage estimates provide a crucial but previously missing component of cost-benefit analyses to evaluate policies and management options intended to reduce species introductions. The modeling approach we developed is highly flexible and could be similarly employed to estimate damages in other countries or natural resource sectors. PMID:21931766

  7. Car Accident Reconstruction and Head Injury Correlation

    NASA Astrophysics Data System (ADS)

    Chawla, A.; Grover, V.; Mukherjee, S.; Hassan, A. M.

    2013-04-01

    Estimation of brain damage remains an elusive issue and controlled tests leading to brain damage cannot be carried out on volunteers. This study reconstructs real-world car accidents to estimate the kinematics of the head impact. This data is to be used to estimate the head injury measures through computer simulations and then correlate reported skull as well as brain damage to impact measures; whence validating the head FE model (Willinger, IJCrash 8:605-617, 2003). In this study, two crash cases were reconstructed. Injury correlation was successful in one of these cases in that the injuries to the brain of one of the car drivers could be correlated in terms of type, location and severity when compared with the tolerance limits of relevant injury parameters (Willinger, IJCrash 8:605-617, 2003).

  8. Decomposition Technique for Remaining Useful Life Prediction

    NASA Technical Reports Server (NTRS)

    Saha, Bhaskar (Inventor); Goebel, Kai F. (Inventor); Saxena, Abhinav (Inventor); Celaya, Jose R. (Inventor)

    2014-01-01

    The prognostic tool disclosed here decomposes the problem of estimating the remaining useful life (RUL) of a component or sub-system into two separate regression problems: the feature-to-damage mapping and the operational conditions-to-damage-rate mapping. These maps are initially generated in off-line mode. One or more regression algorithms are used to generate each of these maps from measurements (and features derived from these), operational conditions, and ground truth information. This decomposition technique allows for the explicit quantification and management of different sources of uncertainty present in the process. Next, the maps are used in an on-line mode where run-time data (sensor measurements and operational conditions) are used in conjunction with the maps generated in off-line mode to estimate both current damage state as well as future damage accumulation. Remaining life is computed by subtracting the instance when the extrapolated damage reaches the failure threshold from the instance when the prediction is made.

  9. Damage and Loss Estimation for Natural Gas Networks: The Case of Istanbul

    NASA Astrophysics Data System (ADS)

    Çaktı, Eser; Hancılar, Ufuk; Şeşetyan, Karin; Bıyıkoǧlu, Hikmet; Şafak, Erdal

    2017-04-01

    Natural gas networks are one of the major lifeline systems to support human, urban and industrial activities. The continuity of gas supply is critical for almost all functions of modern life. Under natural phenomena such as earthquakes and landslides the damages to the system elements may lead to explosions and fires compromising human life and damaging physical environment. Furthermore, the disruption in the gas supply puts human activities at risk and also results in economical losses. This study is concerned with the performance of one of the largest natural gas distribution systems in the world. Physical damages to Istanbul's natural gas network are estimated under the most recent probabilistic earthquake hazard models available, as well as under simulated ground motions from physics based models. Several vulnerability functions are used in modelling damages to system elements. A first-order assessment of monetary losses to Istanbul's natural gas distribution network is also attempted.

  10. Human Lung Cancer Risks from Radon – Part II – Influence from Combined Adaptive Response and Bystander Effects – A Microdose Analysis

    PubMed Central

    Leonard, Bobby E.; Thompson, Richard E.; Beecher, Georgia C.

    2010-01-01

    In the prior Part I, the potential influence of the low level alpha radiation induced bystander effect (BE) on human lung cancer risks was examined. Recent analysis of adaptive response (AR) research results with a Microdose Model has shown that single low LET radiation induced charged particles traversals through the cell nucleus activates AR. We have here conducted an analysis based on what is presently known about adaptive response and the bystander effect (BE) and what new research is needed that can assist in the further evaluation human cancer risks from radon. We find that, at the UNSCEAR (2000) worldwide average human exposures from natural background and man-made radiations, the human lung receives about a 25% adaptive response protection against the radon alpha bystander damage. At the UNSCEAR (2000) minimum range of background exposure levels, the lung receives minimal AR protection but at higher background levels, in the high UNSCEAR (2000) range, the lung receives essentially 100% protection from both the radon alpha damage and also the endogenic, spontaneously occurring, potentially carcinogenic, lung cellular damage. PMID:22461760

  11. Integrated molecular analysis indicates undetectable change in DNA damage in mice after continuous irradiation at ~ 400-fold natural background radiation.

    PubMed

    Olipitz, Werner; Wiktor-Brown, Dominika; Shuga, Joe; Pang, Bo; McFaline, Jose; Lonkar, Pallavi; Thomas, Aline; Mutamba, James T; Greenberger, Joel S; Samson, Leona D; Dedon, Peter C; Yanch, Jacquelyn C; Engelward, Bevin P

    2012-08-01

    In the event of a nuclear accident, people are exposed to elevated levels of continuous low dose-rate radiation. Nevertheless, most of the literature describes the biological effects of acute radiation. DNA damage and mutations are well established for their carcinogenic effects. We assessed several key markers of DNA damage and DNA damage responses in mice exposed to low dose-rate radiation to reveal potential genotoxic effects associated with low dose-rate radiation. We studied low dose-rate radiation using a variable low dose-rate irradiator consisting of flood phantoms filled with 125Iodine-containing buffer. Mice were exposed to 0.0002 cGy/min (~ 400-fold background radiation) continuously over 5 weeks. We assessed base lesions, micronuclei, homologous recombination (HR; using fluorescent yellow direct repeat mice), and transcript levels for several radiation-sensitive genes. We did not observe any changes in the levels of the DNA nucleobase damage products hypoxanthine, 8-oxo-7,8-dihydroguanine, 1,N6-ethenoadenine, or 3,N4-ethenocytosine above background levels under low dose-rate conditions. The micronucleus assay revealed no evidence that low dose-rate radiation induced DNA fragmentation, and there was no evidence of double strand break-induced HR. Furthermore, low dose-rate radiation did not induce Cdkn1a, Gadd45a, Mdm2, Atm, or Dbd2. Importantly, the same total dose, when delivered acutely, induced micronuclei and transcriptional responses. These results demonstrate in an in vivo animal model that lowering the dose-rate suppresses the potentially deleterious impact of radiation and calls attention to the need for a deeper understanding of the biological impact of low dose-rate radiation.

  12. Post-Impact Fatigue Damage Monitoring Using Fiber Bragg Grating Sensors

    PubMed Central

    Shin, Chow-Shing; Liaw, Shien-Kuei; Yang, Shi-Wei

    2014-01-01

    It has been shown that impact damage to composite materials can be revealed by embedded Fiber Bragg Gratings (FBG) as a broadening and splitting of the latter's characteristic narrow peak reflected spectrum. The current work further subjected the impact damaged composite to cyclic loading and found that the FBG spectrum gradually submerged into a rise of background intensity as internal damages progressed. By skipping the impact, directing the impact to positions away from the FBG and examining the extracted fibers, we concluded that the above change is not a result of deterioration/damage of the sensor. It is caused solely by the damages initiated in the composite by the impact and aggravated by fatigue loading. Evolution of the grating spectrum may therefore be used to monitor qualitatively the development of the incurred damages. PMID:24594609

  13. Grinding damage assessment on four high-strength ceramics.

    PubMed

    Canneto, Jean-Jacques; Cattani-Lorente, Maria; Durual, Stéphane; Wiskott, Anselm H W; Scherrer, Susanne S

    2016-02-01

    The purpose of this study was to assess surface and subsurface damage on 4 CAD-CAM high-strength ceramics after grinding with diamond disks of 75 μm, 54 μm and 18 μm and to estimate strength losses based on damage crack sizes. The materials tested were: 3Y-TZP (Lava), dense Al2O3 (In-Ceram AL), alumina glass-infiltrated (In-Ceram ALUMINA) and alumina-zirconia glass-infiltrated (In-Ceram ZIRCONIA). Rectangular specimens with 2 mirror polished orthogonal sides were bonded pairwise together prior to degrading the top polished surface with diamond disks of either 75 μm, 54 μm or 18 μm. The induced chip damage was evaluated on the bonded interface using SEM for chip depth measurements. Fracture mechanics were used to estimate fracture stresses based on average and maximum chip depths considering these as critical flaws subjected to tension and to calculate possible losses in strength compared to manufacturer's data. 3Y-TZP was hardly affected by grinding chip damage viewed on the bonded interface. Average chip depths were of 12.7±5.2 μm when grinding with 75 μm diamond inducing an estimated loss of 12% in strength compared to manufacturer's reported flexural strength values of 1100 MPa. Dense alumina showed elongated chip cracks and was suffering damage of an average chip depth of 48.2±16.3 μm after 75 μm grinding, representing an estimated loss in strength of 49%. Grinding with 54 μm was creating chips of 32.2±9.1 μm in average, representing a loss in strength of 23%. Alumina glass-infiltrated ceramic was exposed to chipping after 75 μm (mean chip size=62.4±19.3 μm) and 54 μm grinding (mean chip size=42.8±16.6 μm), with respectively 38% and 25% estimated loss in strength. Alumina-zirconia glass-infiltrated ceramic was mainly affected by 75 μm grinding damage with a chip average size of 56.8±15.1 μm, representing an estimated loss in strength of 34%. All four ceramics were not exposed to critical chipping at 18 μm diamond grinding. Reshaping a ceramic framework post sintering should be avoided with final diamond grits of 75 μm as a general rule. For alumina and the glass-infiltrated alumina, using a 54 μm diamond still induces chip damage which may affect strength. Removal of such damage from a reshaped framework is mandatory by using sequentially finer diamonds prior to the application of veneering ceramics especially in critical areas such as margins, connectors and inner surfaces. Copyright © 2015 Academy of Dental Materials. Published by Elsevier Ltd. All rights reserved.

  14. The potential impact of ozone on materials in the U.K.

    NASA Astrophysics Data System (ADS)

    Lee, David S.; Holland, Michael R.; Falla, Norman

    Recent reports have highlighted the potential damage caused to a range of media, including materials, by ozone (O 3). The limited data available indicate significant damage to rubber products and surface coatings but either insignificant or unquantifiable damage to textiles and other polymeric materials at the range of atmospheric concentrations encountered in the U.K. Materials in the indoor environment have been excluded from economic analyses. Legislation was put in place in 1993 in the U.K. in order to reduce NO x (NO x = NO + NO 2) and VOC (volatile organic compounds) emissions from motor vehicles which is likely to result in reduced peak O 3 episodes but increased average levels of O 3 in urban areas which may result in increased damage to materials. A detailed assessment of the costs of O 3 damage to materials is not currently possible because of insufficient information on relevant dose-response functions and the stock at risk. Alternative methods were thus adopted to determine the potential scale of the problem. Scaling of U.S. estimates made in the late 1960s provides a range for the U.K. of £170 million-£345 million yr -1 in current terms. This includes damage to surface coatings and elastomers, and the cost of antiozonant protection applied to rubber goods. Independent estimates were made of the costs of protecting rubber goods in the U.K. These were based on the size of the antiozonant market, and provide cost ranges of £25 million-£63 million yr -1 to manufacturers and £25 million-£189 million yr -1 to consumers. The only rubber goods for which a damage estimate (not including protection costs) could be made were tyres, using data from the U.S.A. and information on annual tyre sales in the U.K. A range of £0-£4 million yr -1 was estimated. The cost of damage to other rubber goods could not be quantified because of a lack of data on both the stock at risk and exposure-response functions. The effect of O 3 on the costs of repainting were estimated under scenarios of increased urban concentrations of O 3 using damage functions derived from the literature. The cost was estimated to be in the range of £0-£60 million yr -1 for a change from 15 to 20 ppb O 3, and £0 to £182 million yr -1 for a change from 15 to 30 ppb O 3. The wide ranges derived for effects on surface coatings are a reflection of the uncertainty associated with the dose-response functions used.

  15. Post-hurricane forest damage assessment using satellite remote sensing

    Treesearch

    W. Wang; J.J. Qu; X. Hao; Y. Liu; J.A. Stanturf

    2010-01-01

    This study developed a rapid assessment algorithm for post-hurricane forest damage estimation using moderate resolution imaging spectroradiometer (MODIS) measurements. The performance of five commonly used vegetation indices as post-hurricane forest damage indicators was investigated through statistical analysis. The Normalized Difference Infrared Index (NDII) was...

  16. 43 CFR 11.84 - Damage determination phase-implementation guidance.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... the damage assessment. (2) Natural resource damages are the residual to be determined by incorporating... estimates of natural recovery rates as well as recovery rates that reflect management actions or resource... actions or resource acquisitions, including a “No Action-Natural Recovery” alternative. After the recovery...

  17. [Valuation of forest damage cost from SO2 emission: a case study in Hunan Province].

    PubMed

    Hao, Jiming; Li, Ji; Duan, Lei; He, Kebin; Dai, Wennan

    2002-11-01

    Large amount SO2 emission caused serious damage of forest ecosystem in China and calculation of the damage cost is an important issue for policy-making. However, no applicable method was developed to estimate forest damage under different SO2 emission scenarios. Basing on previous field researches on sulfur-related forest impact in China and recent critical load mapping research, this paper presented a model for forest damage calculation by developing a dose-response function that related the damage to cumulative sulfur critical loads. This model was applied to the forests in Hunan, a province in acid rain control zone in China. Results showed that in the business-as-usual case, SO2 emission in Hunan will increase by 120% from 1995 (8.82 mil. ton) to 2020 (19.56 mil. ton), but damage cost will increase by 4.3 times, reaching 6.19 billion RMB in 2020. Results also showed the measures for SO2 control were cost-effective because the marginal damage cost will be about 6000 RMB per ton SO2 in 2020 in BAU case. At current SO2 emission level, marginal benefit will be about 1500 RMB per ton. Uncertainty analysis demonstrated that this model provides reasonable damage estimates and would therefore be applicable in a broad range of policy settings.

  18. Plasma NT-proBNP mirrors the deleterious cardiovascular and renal continuum in hypertension.

    PubMed

    Courand, Pierre-Yves; Harbaoui, Brahim; Bècle, Clément; Mouly-Bertin, Carine; Lantelme, Pierre

    2017-03-01

    Background The aims of this study were (a) to test the ability of N-terminal pro-brain natriuretic peptide (NT-proBNP) to detect subclinical target organ damage (TOD) denoted by left ventricular hypertrophy (LVH), aortic stiffness or renal damage and (b) to test its reproducibility in two different conditions in an ancillary study. Methods The study included 837 patients (50.9% men) with hypertension aged 50 ± 24 years with a median 24-h ambulatory blood pressure (BP) of 148/90 mmHg. LVH was assessed by transthoracic echocardiography and echocardiography, aortic stiffness was assessed by carotid-femoral pulse wave (PWV) measurements and renal dysfunction by measurements of the estimated glomerular filtration rate (eGFR) and microalbuminuria. Results After the exclusion of patients with a history of heart failure, NT-proBNP was independently correlated with sex, systolic BP, primary hypertension, PWV, LVH and eGFR, but not with microalbuminuria. The median (interquartile range) NT-proBNP increased gradually according to the number of target organs damaged: 42 (24-70), 77 (39-151), 141 (81-250) and 334 (177-556) pg/mL, for damage to 0, 1, 2 and 3 target organs, respectively ( p < 0.001). . For the same number of target organs damaged, NT-proBNP was higher in women and for secondary hypertension. A threshold at 90 pg/mL for men and 142 pg/mL in women had a specificity of 95% to detect at least one TOD (areas under ROC curve 0.790 and 0.783, respectively). The reproducibility of NT-proBNP was fairly good in this setting ( r = 0.952, p < 0.001, N = 325) Conclusion This study demonstrates that NT-proBNP mirrors the harmful effect of high BP on TOD. NT-proBNP could be used as an integrative tool for risk stratification in hypertension.

  19. Design of intelligent composites with life-cycle health management capabilities

    NASA Astrophysics Data System (ADS)

    Rosania, Colleen L.; Larrosa, Cecilia C.; Chang, Fu-Kuo

    2015-03-01

    Use of carbon fiber reinforced polymers (CFRPs) presents challenges because of their complex manufacturing processes and different damage mechanics in relation to legacy metal materials. New monitoring methods for manufacturing, quality verification, damage estimation, and prognosis are needed to use CFRPs safely and efficiently. This work evaluates the development of intelligent composite materials using integrated piezoelectric sensors to monitor the material during cure and throughout service life. These sensors are used to propagate ultrasonic waves through the structure for health monitoring. During manufacturing, data is collected at different stages during the cure cycle, detecting the changing material properties during cure and verifying quality and degree of cure. The same sensors can then be used with previously developed techniques to perform damage detection, such as impact detection and matrix crack density estimation. Real-time damage estimation can be combined with prognostic models to predict future propagation of damage in the material. In this work experimental results will be presented from composite coupons with embedded piezoelectric sensors. Cure monitoring and damage detection results derived from analysis of the ultrasonic sensor signal will be shown. Sensitive signal parameters to the different stimuli in both the time and frequency domains will be explored for this analysis. From these results, use of the same sensor networks from manufacturing throughout the life of the composite material will demonstrate the full life-cycle monitoring capability of these intelligent materials.

  20. Extended Kalman filtering for the detection of damage in linear mechanical structures

    NASA Astrophysics Data System (ADS)

    Liu, X.; Escamilla-Ambrosio, P. J.; Lieven, N. A. J.

    2009-09-01

    This paper addresses the problem of assessing the location and extent of damage in a vibrating structure by means of vibration measurements. Frequency domain identification methods (e.g. finite element model updating) have been widely used in this area while time domain methods such as the extended Kalman filter (EKF) method, are more sparsely represented. The difficulty of applying EKF in mechanical system damage identification and localisation lies in: the high computational cost, the dependence of estimation results on the initial estimation error covariance matrix P(0), the initial value of parameters to be estimated, and on the statistics of measurement noise R and process noise Q. To resolve these problems in the EKF, a multiple model adaptive estimator consisting of a bank of EKF in modal domain was designed, each filter in the bank is based on different P(0). The algorithm was iterated by using the weighted global iteration method. A fuzzy logic model was incorporated in each filter to estimate the variance of the measurement noise R. The application of the method is illustrated by simulated and real examples.

  1. Methodologies for Adaptive Flight Envelope Estimation and Protection

    NASA Technical Reports Server (NTRS)

    Tang, Liang; Roemer, Michael; Ge, Jianhua; Crassidis, Agamemnon; Prasad, J. V. R.; Belcastro, Christine

    2009-01-01

    This paper reports the latest development of several techniques for adaptive flight envelope estimation and protection system for aircraft under damage upset conditions. Through the integration of advanced fault detection algorithms, real-time system identification of the damage/faulted aircraft and flight envelop estimation, real-time decision support can be executed autonomously for improving damage tolerance and flight recoverability. Particularly, a bank of adaptive nonlinear fault detection and isolation estimators were developed for flight control actuator faults; a real-time system identification method was developed for assessing the dynamics and performance limitation of impaired aircraft; online learning neural networks were used to approximate selected aircraft dynamics which were then inverted to estimate command margins. As off-line training of network weights is not required, the method has the advantage of adapting to varying flight conditions and different vehicle configurations. The key benefit of the envelope estimation and protection system is that it allows the aircraft to fly close to its limit boundary by constantly updating the controller command limits during flight. The developed techniques were demonstrated on NASA s Generic Transport Model (GTM) simulation environments with simulated actuator faults. Simulation results and remarks on future work are presented.

  2. Modeled changes in 100 year Flood Risk and Asset Damages within Mapped Floodplains of the Contiguous United States

    NASA Astrophysics Data System (ADS)

    Wobus, C. W.; Gutmann, E. D.; Jones, R.; Rissing, M.; Mizukami, N.; Lorie, M.; Mahoney, H.; Wood, A.; Mills, D.; Martinich, J.

    2017-12-01

    A growing body of recent work suggests that the extreme weather events that drive inland flooding are likely to increase in frequency and magnitude in a warming climate, thus increasing monetary damages from flooding in the future. We use hydrologic projections based on the Coupled Model Intercomparison Project Phase 5 (CMIP5) to estimate changes in the frequency of modeled 1% annual exceedance probability flood events at 57,116 locations across the contiguous United States (CONUS). We link these flood projections to a database of assets within mapped flood hazard zones to model changes in inland flooding damages throughout the CONUS over the remainder of the 21st century, under two greenhouse gas (GHG) emissions scenarios. Our model generates early 21st century flood damages that reasonably approximate the range of historical observations, and trajectories of future damages that vary substantially depending on the GHG emissions pathway. The difference in modeled flood damages between higher and lower emissions pathways approaches $4 billion per year by 2100 (in undiscounted 2014 dollars), suggesting that aggressive GHG emissions reductions could generate significant monetary benefits over the long-term in terms of reduced flood risk. Although the downscaled hydrologic data we used have been applied to flood impacts studies elsewhere, this research expands on earlier work to quantify changes in flood risk by linking future flood exposure to assets and damages at a national scale. Our approach relies on a series of simplifications that could ultimately affect damage estimates (e.g., use of statistical downscaling, reliance on a nationwide hydrologic model, and linking damage estimates only to 1% AEP floods). Although future work is needed to test the sensitivity of our results to these methodological choices, our results suggest that monetary damages from inland flooding could be substantially reduced through more aggressive GHG mitigation policies.

  3. Estimation of channel parameters and background irradiance for free-space optical link.

    PubMed

    Khatoon, Afsana; Cowley, William G; Letzepis, Nick; Giggenbach, Dirk

    2013-05-10

    Free-space optical communication can experience severe fading due to optical scintillation in long-range links. Channel estimation is also corrupted by background and electrical noise. Accurate estimation of channel parameters and scintillation index (SI) depends on perfect removal of background irradiance. In this paper, we propose three different methods, the minimum-value (MV), mean-power (MP), and maximum-likelihood (ML) based methods, to remove the background irradiance from channel samples. The MV and MP methods do not require knowledge of the scintillation distribution. While the ML-based method assumes gamma-gamma scintillation, it can be easily modified to accommodate other distributions. Each estimator's performance is compared using simulation data as well as experimental measurements. The estimators' performance are evaluated from low- to high-SI areas using simulation data as well as experimental trials. The MV and MP methods have much lower complexity than the ML-based method. However, the ML-based method shows better SI and background-irradiance estimation performance.

  4. Risk-rating Saratoga Spittlebug Damage by Abundance of Alternate-host Plants

    Treesearch

    Louis F. Wilson

    1971-01-01

    The potential damage of the Saratoga spittlebug to red pine can be predicted by comparing the percentage of ground occupied by sweet-fern with the percentage of ground cover occupied by other nymphal host plants. A risk-rating graph is used to estimate potential damage.

  5. Estimation of human damage and economic loss of buildings for the worst-credible scenario of tsunami inundation in the city of Augusta, Italy

    NASA Astrophysics Data System (ADS)

    Pagnoni, Gianluca; Tinti, Stefano

    2017-04-01

    The city of Augusta is located in the southern part of the eastern coast of Sicily. Italian tsunami catalogue and paleo-tsunami surveys indicate that at least 7 events of tsunami affected the bay of Augusta in the last 4,000 years, two of which are associated with earthquakes (1169 and 1693) that destroyed the city. For these reasons Augusta has been chosen in the project ASTARTE as a test site for the study of issues related to tsunami hazard and risk. In last two years we studied hazard through the approach of the worst-case credible scenario and carried out vulnerability and damage analysis for buildings. In this work, we integrate that research, and estimate the damage to people and the economic loss of buildings due to structural damage. As regards inundation, we assume both uniform inundation levels (bath-tub hypothesis) and inundation data resulting from the worst-case scenario elaborated for the area by Armigliato et al. (2015). Human damage is calculated in three steps using the method introduced by Pagnoni et al. (2016) following the work by Terrier et al. (2012) and by Koshimura et al. (2009). First, we use census data to estimate the number of people present in each residential building affected by inundation; second, based on water column depth and building type, we evaluate the level of damage to people; third, we provide an estimate of fatalities. The economic loss is computed for two types of buildings (residential and trade-industrial) by using data on inundation and data from the real estate market. This study was funded by the EU Project ASTARTE - "Assessment, STrategy And Risk Reduction for Tsunamis in Europe", Grant 603839, 7th FP (ENV.2013.6.4-3)

  6. Simulating Direct and Indirect Damages to Commercial Fisheries from Marine Sand Mining: A Case Study in Korea

    NASA Astrophysics Data System (ADS)

    Kim, Tae-Guon; Grigalunas, Thomas

    2009-09-01

    Rapid growth in marine sand mining for construction and other uses poses environmental challenges to coastal nations virtually worldwide. Yet the development of management policies, such as a system of fees imposed on operators for damage caused by mining, has been frustrated by a lack of studies to support such measures. Adapting a Beverton-Holt bioeconomic model, this paper attempts to contribute to the estimation of external costs to commercial fisheries due to marine mining. Using the major mining area of Ongjin in Korea as a case study, we estimate economic losses in use value of commercial fisheries through the time to recovery of the injured resource stocks. Present value of lost catch over a 1-year period from mining to resource recovery is estimated at 38,851 for a single “prototype” mining site. Estimated cumulative damages due to recurring mining for 5 and 10 years are 1.5 million and 2.2 million, respectively, at 20 mining sites. Sensitivity analyses are used to examine the effects of alternative assumptions to assess the many sources of uncertainty. Using a form of meta-analysis, dose-response information is used to assess the excess mortality the mining sediment plume has on eggs and larvae and, ultimately, on the value of lost catch (841). Also addressed is the importance of specifying the appropriate “premining” conditions against which to assess environmental losses at the mining site. Damages estimated with premining fish populations are 23,066 higher than is the case using postmining conditions. Overall, the illustrative results suggest the variety of complex conditions which influence damage to fisheries from mining and which can benefit from further study to improve management guidelines.

  7. Developing building-damage scales for lahars: application to Merapi volcano, Indonesia

    NASA Astrophysics Data System (ADS)

    Jenkins, Susanna F.; Phillips, Jeremy C.; Price, Rebecca; Feloy, Kate; Baxter, Peter J.; Hadmoko, Danang Sri; de Bélizal, Edouard

    2015-09-01

    Lahar damage to buildings can include burial by sediment and/or failure of walls, infiltration into the building and subsequent damage to contents. The extent to which a building is damaged will be dictated by the dynamic characteristics of the lahar, i.e. the velocity, depth, sediment concentration and grain size, as well as the structural characteristics and setting of the building in question. The focus of this paper is on quantifying how buildings may respond to impact by lahar. We consider the potential for lahar damage to buildings on Merapi volcano, Indonesia, as a result of the voluminous deposits produced during the large (VEI 4) eruption in 2010. A building-damage scale has been developed that categorises likely lahar damage levels and, through theoretical calculations of expected building resistance to impact, approximate ranges of impact pressures. We found that most weak masonry buildings on Merapi would be destroyed by dilute lahars with relatively low velocities (ca. 3 m/s) and pressures (ca. 5 kPa); however, the majority of stronger rubble stone buildings may be expected to withstand higher velocities (to 6 m/s) and pressures (to 20 kPa). We applied this preliminary damage scale to a large lahar in the Putih River on 9 January 2011, which inundated and caused extensive building damage in the village of Gempol, 16 km southwest of Merapi. The scale was applied remotely through the use of public satellite images and through field studies to categorise damage and estimate impact pressures and velocities within the village. Results were compared with those calculated independently from Manning's calculations for flow velocity and depth within Gempol village using an estimate of flow velocity at one upstream site as input. The results of this calculation showed reasonable agreement with an average channel velocity derived from travel time observations. The calculated distribution of flow velocities across the area of damaged buildings was consistent with building damage as classified by the new damage scale. The complementary results, even given the basic nature of the tools and data, suggest that the damage scale provides a valid representation of the failure mode that is consistent with estimates of the flow conditions. The use of open-source simplified tools and data in producing these consistent findings is very promising.

  8. A study to compute integrated dpa for neutron and ion irradiation environments using SRIM-2013

    NASA Astrophysics Data System (ADS)

    Saha, Uttiyoarnab; Devan, K.; Ganesan, S.

    2018-05-01

    Displacements per atom (dpa), estimated based on the standard Norgett-Robinson-Torrens (NRT) model, is used for assessing radiation damage effects in fast reactor materials. A computer code CRaD has been indigenously developed towards establishing the infrastructure to perform improved radiation damage studies in Indian fast reactors. We propose a method for computing multigroup neutron NRT dpa cross sections based on SRIM-2013 simulations. In this method, for each neutron group, the recoil or primary knock-on atom (PKA) spectrum and its average energy are first estimated with CRaD code from ENDF/B-VII.1. This average PKA energy forms the input for SRIM simulation, wherein the recoil atom is taken as the incoming ion on the target. The NRT-dpa cross section of iron computed with "Quick" Kinchin-Pease (K-P) option of SRIM-2013 is found to agree within 10% with the standard NRT-dpa values, if damage energy from SRIM simulation is used. SRIM-2013 NRT-dpa cross sections applied to estimate the integrated dpa for Fe, Cr and Ni are in good agreement with established computer codes and data. A similar study carried out for polyatomic material, SiC, shows encouraging results. In this case, it is observed that the NRT approach with average lattice displacement energy of 25 eV coupled with the damage energies from the K-P option of SRIM-2013 gives reliable displacement cross sections and integrated dpa for various reactor spectra. The source term of neutron damage can be equivalently determined in the units of dpa by simulating self-ion bombardment. This shows that the information of primary recoils obtained from CRaD can be reliably applied to estimate the integrated dpa and damage assessment studies in accelerator-based self-ion irradiation experiments of structural materials. This study would help to advance the investigation of possible correlations between the damages induced by ions and reactor neutrons.

  9. Estimating suitable environments for invasive plant species across large landscapes: a remote sensing strategy using Landsat 7 ETM+

    USGS Publications Warehouse

    Young, Kendal E.; Abbott, Laurie B.; Caldwell, Colleen A.; Schrader, T. Scott

    2013-01-01

    The key to reducing ecological and economic damage caused by invasive plant species is to locate and eradicate new invasions before they threaten native biodiversity and ecological processes. We used Landsat Enhanced Thematic Mapper Plus imagery to estimate suitable environments for four invasive plants in Big Bend National Park, southwest Texas, using a presence-only modeling approach. Giant reed (Arundo donax), Lehmann lovegrass (Eragrostis lehmanniana), horehound (Marrubium vulgare) and buffelgrass (Pennisteum ciliare) were selected for remote sensing spatial analyses. Multiple dates/seasons of imagery were used to account for habitat conditions within the study area and to capture phenological differences among targeted species and the surrounding landscape. Individual species models had high (0.91 to 0.99) discriminative ability to differentiate invasive plant suitable environments from random background locations. Average test area under the receiver operating characteristic curve (AUC) ranged from 0.91 to 0.99, indicating that plant predictive models exhibited high discriminative ability to differentiate suitable environments for invasive plant species from random locations. Omission rates ranged from <1.0 to 18%. We demonstrated that useful models estimating suitable environments for invasive plants may be created with <50 occurrence locations and that reliable modeling using presence-only datasets can be powerful tools for land managers.

  10. On experimental damage localization by SP2E: Application of H∞ estimation and oblique projections

    NASA Astrophysics Data System (ADS)

    Lenzen, Armin; Vollmering, Max

    2018-05-01

    In this article experimental damage localization based on H∞ estimation and state projection estimation error (SP2E) is studied. Based on an introduced difference process, a state space representation is derived for advantageous numerical solvability. Because real structural excitations are presumed to be unknown, a general input is applied therein, which allows synchronization and normalization. Furthermore, state projections are introduced to enhance damage identification. While first experiments to verify method SP2E have already been conducted and published, further laboratory results are analyzed here. Therefore, SP2E is used to experimentally localize stiffness degradations and mass alterations. Furthermore, the influence of projection techniques is analyzed. In summary, method SP2E is able to localize structural alterations, which has been observed by results of laboratory experiments.

  11. Mathematical Methods for Studying DNA and Protein Interactions

    NASA Astrophysics Data System (ADS)

    LeGresley, Sarah

    Deoxyribnucleic Acid (DNA) damage can lead to health related issues such as developmental disorders, aging, and cancer. It has been estimated that damage rates may be as high as 100,000 per cell per day. Because of the devastating effects that DNA damage can have, DNA repair mechanisms are of great interest yet are not completely understood. To gain a better understanding of possible DNA repair mechanisms, my dissertation focused on mathematical methods for understanding the interactions between DNA and proteins. I developed a damaged DNA model to estimate the probabilities of damaged DNA being located at specific positions. Experiments were then performed that suggested that the damaged DNA may be repositioned. These experimental results were consistent with the model's prediction that damaged DNA has preferred locations. To study how proteins might be moving along the DNA, I studied the use of the uniform motion "n-step" model. The n-step model has been used to determine the kinetics parameters (e.g. rates at which a protein moves along the DNA, how much energy is required to move a protein along a specified amount of DNA, etc.) of proteins moving along the DNA. Monte Carlo methods were used to simulate proteins moving with different types of non-uniform motion (e.g. backward, jumping, etc.) along the DNA. Estimates for the kinetics parameters in the n-step model were found by fitting of the Monte Carlo simulation data. Analysis indicated that non-uniform motion of the protein may lead to over or underestimation of the kinetic parameters of this n-step model.

  12. A robust background regression based score estimation algorithm for hyperspectral anomaly detection

    NASA Astrophysics Data System (ADS)

    Zhao, Rui; Du, Bo; Zhang, Liangpei; Zhang, Lefei

    2016-12-01

    Anomaly detection has become a hot topic in the hyperspectral image analysis and processing fields in recent years. The most important issue for hyperspectral anomaly detection is the background estimation and suppression. Unreasonable or non-robust background estimation usually leads to unsatisfactory anomaly detection results. Furthermore, the inherent nonlinearity of hyperspectral images may cover up the intrinsic data structure in the anomaly detection. In order to implement robust background estimation, as well as to explore the intrinsic data structure of the hyperspectral image, we propose a robust background regression based score estimation algorithm (RBRSE) for hyperspectral anomaly detection. The Robust Background Regression (RBR) is actually a label assignment procedure which segments the hyperspectral data into a robust background dataset and a potential anomaly dataset with an intersection boundary. In the RBR, a kernel expansion technique, which explores the nonlinear structure of the hyperspectral data in a reproducing kernel Hilbert space, is utilized to formulate the data as a density feature representation. A minimum squared loss relationship is constructed between the data density feature and the corresponding assigned labels of the hyperspectral data, to formulate the foundation of the regression. Furthermore, a manifold regularization term which explores the manifold smoothness of the hyperspectral data, and a maximization term of the robust background average density, which suppresses the bias caused by the potential anomalies, are jointly appended in the RBR procedure. After this, a paired-dataset based k-nn score estimation method is undertaken on the robust background and potential anomaly datasets, to implement the detection output. The experimental results show that RBRSE achieves superior ROC curves, AUC values, and background-anomaly separation than some of the other state-of-the-art anomaly detection methods, and is easy to implement in practice.

  13. Influence of fruit age of the Brazilian Green Dwarf coconut on the relationship between Aceria guerreronis population density and percentage of fruit damage.

    PubMed

    Sousa, André Silva Guimarães; Argolo, Poliane Sá; Gondim, Manoel Guedes Correa; de Moraes, Gilberto José; Oliveira, Anibal Ramadan

    2017-08-01

    The coconut mite, Aceria guerreronis Keifer (Acari: Eriophyidae), is one of the main coconut pests in the American, African and parts of the Asian continents, reaching densities of several thousand mites per fruit. Diagrammatic scales have been developed to standardize the estimation of the population densities of A. guerreronis according to the estimated percentage of damage, but these have not taken into account the possible effect of fruit age, although previous studies have already reported the variation in mite numbers with fruit age. The objective of this study was to re-construct the relation between damage and mite density at different fruit ages collected in an urban coconut plantation containing the green dwarf variety ranging from the beginning to nearly the end of the infestation, as regularly seen under field conditions in northeast Brazil, in order to improve future estimates with diagrammatic scales. The percentage of damage was estimated with two diagrammatic scales on a total of 470 fruits from 1 to 5 months old, from a field at Ilhéus, Bahia, Brazil, determining the respective number of mites on each fruit. The results suggested that in estimates with diagrammatic scales: (1) fruit age has a major effect on the estimation of A. guerreronis densities, (2) fruits of different ages should be analyzed separately, and (3) regular evaluation of infestation levels should be done preferably on fruits of about 3-4 months old, which show the highest densities.

  14. Forest pests and home values: The importance of accuracy in damage assessment and geocoding of properties

    Treesearch

    Klaus Moeltner; Christine E. Blinn; Thomas P. Holmes

    2017-01-01

    We examine the impact of measurement errors in geocoding of property locations and in the assessment of Mountain Pine Beetle-induced tree damage within the proximity of a given residence on estimated losses in home values. For our sample of homes in the wildland-urban interface of the Colorado front range and using a novel matching estimator with Bayesian regression...

  15. Evaluation of Progressive Failure Analysis and Modeling of Impact Damage in Composite Pressure Vessels

    NASA Technical Reports Server (NTRS)

    Sanchez, Christopher M.

    2011-01-01

    NASA White Sands Test Facility (WSTF) is leading an evaluation effort in advanced destructive and nondestructive testing of composite pressure vessels and structures. WSTF is using progressive finite element analysis methods for test design and for confirmation of composite pressure vessel performance. Using composite finite element analysis models and failure theories tested in the World-Wide Failure Exercise, WSTF is able to estimate the static strength of composite pressure vessels. Additionally, test and evaluation on composites that have been impact damaged is in progress so that models can be developed to estimate damage tolerance and the degradation in static strength.

  16. Estimate of radiation damage to low-level electronics of the RF system in the LHC cavities arising from beam gas collisions.

    PubMed

    Butterworth, A; Ferrari, A; Tsoulou, E; Vlachoudis, V; Wijnands, T

    2005-01-01

    Monte Carlo simulations have been performed to estimate the radiation damage induced by high-energy hadrons in the digital electronics of the RF low-level systems in the LHC cavities. High-energy hadrons are generated when the proton beams interact with the residual gas. The contributions from various elements-vacuum chambers, cryogenic cavities, wideband pickups and cryomodule beam tubes-have been considered individually, with each contribution depending on the gas composition and density. The probability of displacement damage and single event effects (mainly single event upsets) is derived for the LHC start-up conditions.

  17. Detection of multiple damages employing best achievable eigenvectors under Bayesian inference

    NASA Astrophysics Data System (ADS)

    Prajapat, Kanta; Ray-Chaudhuri, Samit

    2018-05-01

    A novel approach is presented in this work to localize simultaneously multiple damaged elements in a structure along with the estimation of damage severity for each of the damaged elements. For detection of damaged elements, a best achievable eigenvector based formulation has been derived. To deal with noisy data, Bayesian inference is employed in the formulation wherein the likelihood of the Bayesian algorithm is formed on the basis of errors between the best achievable eigenvectors and the measured modes. In this approach, the most probable damage locations are evaluated under Bayesian inference by generating combinations of various possible damaged elements. Once damage locations are identified, damage severities are estimated using a Bayesian inference Markov chain Monte Carlo simulation. The efficiency of the proposed approach has been demonstrated by carrying out a numerical study involving a 12-story shear building. It has been found from this study that damage scenarios involving as low as 10% loss of stiffness in multiple elements are accurately determined (localized and severities quantified) even when 2% noise contaminated modal data are utilized. Further, this study introduces a term parameter impact (evaluated based on sensitivity of modal parameters towards structural parameters) to decide the suitability of selecting a particular mode, if some idea about the damaged elements are available. It has been demonstrated here that the accuracy and efficiency of the Bayesian quantification algorithm increases if damage localization is carried out a-priori. An experimental study involving a laboratory scale shear building and different stiffness modification scenarios shows that the proposed approach is efficient enough to localize the stories with stiffness modification.

  18. Multiple Damage Progression Paths in Model-Based Prognostics

    NASA Technical Reports Server (NTRS)

    Daigle, Matthew; Goebel, Kai Frank

    2011-01-01

    Model-based prognostics approaches employ domain knowledge about a system, its components, and how they fail through the use of physics-based models. Component wear is driven by several different degradation phenomena, each resulting in their own damage progression path, overlapping to contribute to the overall degradation of the component. We develop a model-based prognostics methodology using particle filters, in which the problem of characterizing multiple damage progression paths is cast as a joint state-parameter estimation problem. The estimate is represented as a probability distribution, allowing the prediction of end of life and remaining useful life within a probabilistic framework that supports uncertainty management. We also develop a novel variance control mechanism that maintains an uncertainty bound around the hidden parameters to limit the amount of estimation uncertainty and, consequently, reduce prediction uncertainty. We construct a detailed physics-based model of a centrifugal pump, to which we apply our model-based prognostics algorithms. We illustrate the operation of the prognostic solution with a number of simulation-based experiments and demonstrate the performance of the chosen approach when multiple damage mechanisms are active

  19. 77 FR 25371 - Transportation of Household Goods in Interstate Commerce; Consumer Protection Regulations...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-30

    ... services when the shipper agrees to release the carrier from full liability for potential loss and damage... implemented a congressional directive to enhance consumer protection in cases of loss or damage that occur... the estimates they provide to prospective shippers: WARNING: If a moving company loses or damages your...

  20. Estimation of Damage Costs Associated with Flood Events

    NASA Astrophysics Data System (ADS)

    Andrews, T. A.; Wauthier, C.; Zipp, K.

    2017-12-01

    This study investigates the possibility of creating a mathematical function that enables the estimation of flood-damage costs. We begin by examining the costs associated with past flood events in the United States. The data on these tropical storms and hurricanes are provided by the National Oceanic and Atmospheric Administration. With the location, extent of flooding, and damage reparation costs identified, we analyze variables such as: number of inches rained, land elevation, type of landscape, region development in regards to building density and infrastructure, and population concentration. We seek to identify the leading drivers of high flood-damage costs and understand which variables play a large role in the costliness of these weather events. Upon completion of our mathematical analysis, we turn out attention to the 2017 natural disaster of Texas. We divide the region, as we did above, by land elevation, type of landscape, region development in regards to building density and infrastructure, and population concentration. Then, we overlay the number of inches rained in those regions onto the divided landscape and apply our function. We hope to use these findings to estimate the potential flood-damage costs of Hurricane Harvey. This information is then transformed into a hazard map that could provide citizens and businesses of flood-stricken zones additional resources for their insurance selection process.

  1. GPR measurements and estimation for road subgrade damage caused by neighboring train vibration load

    NASA Astrophysics Data System (ADS)

    Zhao, Yonghui; Lu, Gang; Ge, Shuangcheng

    2015-04-01

    Generally, road can be simplified as a three-layer structure, including subgrade, subbase and pavement. Subgrade is the native material underneath a constructed road. It is commonly compacted before the road construction, and sometimes stabilized by the addition of asphalt, lime or other modifiers. As the mainly supporting structure, subgrade damage would lead in pavement settlement, displacement and crack. Assessment and monitoring of the subgrade condition currently involves trial pitting and subgrade sampling. However there is a practical limit on spatial density at which trail pits and cores can be taken. Ground penetrating radar (GPR) has been widely used to characterize highway pavement profiling, concrete structure inspection and railroad track ballast estimation. GPR can improve the economics of road maintenance. Long-term train vibration load might seriously influence the stability of the subgrade of neighboring road. Pavement settlement and obvious cracks have been found at a municipal road cross-under a railway with culvert box method. GPR test was conducted to estimate the subgrade and soil within 2.0 m depth for the further road maintenance. Two survey lines were designed in each lane, and total 12 GPR sections have been implemented. Considering both the penetrating range and the resolution, a antenna with a 500 MHz central frequency was chosen for on-site GPR data collection. For data acquisition, we used the default operating environment and scanning parameters for the RAMAC system: 60kHz transmission rate, 50 ns time window, 1024 samples per scan and 0.1 m step-size. Continuous operation was used; the antenna was placed on the road surface and slowly moved along the road. The strong surrounding disturbance related to railroad and attachments, might decrease the reliability of interpretation results. Some routine process methods (including the background removing, filtering) have been applied to suppress the background noise. Additionally, attribute analysis is an important tool that focused on the multi-properties of the signal. Here, cross-correlation attribute analysis has been applied for GPR profile interpretation. It compares one trace with surrounding traces to determine degrees of similar, and improves the difference between the reflected wave from detection target and its surrounding mediums, which makes it easy to detect the anomaly that couldn't be found in original GPR time profile. It's possible to identify sections of subgrade in good or worse condition, which may require specific maintenance or trail pitting investigation.

  2. "Stronger than the Storm": Keeping Infants and Young Children in Mind During the Response to Superstorm Sandy

    ERIC Educational Resources Information Center

    Costa, Gerard; Mulrooney, Kathleen; Spinazzola, Nicci

    2013-01-01

    Superstorm Sandy hit the coast of New Jersey with deadly force causing hundreds of miles of coastline damage, loss of homes, property and road damage, and power outages throughout the region. despite the state's strong disaster response network, most programs and responders have little background in supporting the needs of infants and very young…

  3. ELER software - a new tool for urban earthquake loss assessment

    NASA Astrophysics Data System (ADS)

    Hancilar, U.; Tuzun, C.; Yenidogan, C.; Erdik, M.

    2010-12-01

    Rapid loss estimation after potentially damaging earthquakes is critical for effective emergency response and public information. A methodology and software package, ELER-Earthquake Loss Estimation Routine, for rapid estimation of earthquake shaking and losses throughout the Euro-Mediterranean region was developed under the Joint Research Activity-3 (JRA3) of the EC FP6 Project entitled "Network of Research Infrastructures for European Seismology-NERIES". Recently, a new version (v2.0) of ELER software has been released. The multi-level methodology developed is capable of incorporating regional variability and uncertainty originating from ground motion predictions, fault finiteness, site modifications, inventory of physical and social elements subjected to earthquake hazard and the associated vulnerability relationships. Although primarily intended for quasi real-time estimation of earthquake shaking and losses, the routine is also equally capable of incorporating scenario-based earthquake loss assessments. This paper introduces the urban earthquake loss assessment module (Level 2) of the ELER software which makes use of the most detailed inventory databases of physical and social elements at risk in combination with the analytical vulnerability relationships and building damage-related casualty vulnerability models for the estimation of building damage and casualty distributions, respectively. Spectral capacity-based loss assessment methodology and its vital components are presented. The analysis methods of the Level 2 module, i.e. Capacity Spectrum Method (ATC-40, 1996), Modified Acceleration-Displacement Response Spectrum Method (FEMA 440, 2005), Reduction Factor Method (Fajfar, 2000) and Coefficient Method (ASCE 41-06, 2006), are applied to the selected building types for validation and verification purposes. The damage estimates are compared to the results obtained from the other studies available in the literature, i.e. SELENA v4.0 (Molina et al., 2008) and ATC-55 (Yang, 2005). An urban loss assessment exercise for a scenario earthquake for the city of Istanbul is conducted and physical and social losses are presented. Damage to the urban environment is compared to the results obtained from similar software, i.e. KOERILoss (KOERI, 2002) and DBELA (Crowley et al., 2004). The European rapid loss estimation tool is expected to help enable effective emergency response, on both local and global level, as well as public information.

  4. The debt of nations and the distribution of ecological impacts from human activities

    PubMed Central

    Srinivasan, U. Thara; Carey, Susan P.; Hallstein, Eric; Higgins, Paul A. T.; Kerr, Amber C.; Koteen, Laura E.; Smith, Adam B.; Watson, Reg; Harte, John; Norgaard, Richard B.

    2008-01-01

    As human impacts to the environment accelerate, disparities in the distribution of damages between rich and poor nations mount. Globally, environmental change is dramatically affecting the flow of ecosystem services, but the distribution of ecological damages and their driving forces has not been estimated. Here, we conservatively estimate the environmental costs of human activities over 1961–2000 in six major categories (climate change, stratospheric ozone depletion, agricultural intensification and expansion, deforestation, overfishing, and mangrove conversion), quantitatively connecting costs borne by poor, middle-income, and rich nations to specific activities by each of these groups. Adjusting impact valuations for different standards of living across the groups as commonly practiced, we find striking imbalances. Climate change and ozone depletion impacts predicted for low-income nations have been overwhelmingly driven by emissions from the other two groups, a pattern also observed for overfishing damages indirectly driven by the consumption of fishery products. Indeed, through disproportionate emissions of greenhouse gases alone, the rich group may have imposed climate damages on the poor group greater than the latter's current foreign debt. Our analysis provides prima facie evidence for an uneven distribution pattern of damages across income groups. Moreover, our estimates of each group's share in various damaging activities are independent from controversies in environmental valuation methods. In a world increasingly connected ecologically and economically, our analysis is thus an early step toward reframing issues of environmental responsibility, development, and globalization in accordance with ecological costs. PMID:18212119

  5. Assessing the Economic Cost of Landslide Damage in Low-Relief Regions: Case Study Evidence from the Flemish Ardennes (Belgium)

    NASA Astrophysics Data System (ADS)

    Vranken, L.; Van Turnhout, P.; Van Den Eeckhaut, M.; Vandekerckhove, L.; Vantilt, G.; Poesen, J.

    2012-04-01

    Several regions around the globe are at risk to incur damage from landslides. These landslides cause significant structural and functional damage to public and private buildings and infrastructure. Numerous studies investigated how natural factors and human activities control the (re-)activation of landslides. However, few studies have concentrated on a quantitative estimate of the overall damage caused by landslides at a regional scale. This study therefore starts with a quantitative economic assessment of the direct and indirect damage caused by landslides in the Flemish Ardennes (Belgium), a low-relief region (area=ca. 700 km2) susceptible to landslides. Based on focus interviews as well as on semi-structured interviews with homeowners, civil servants (e.g. from the technical services from the various towns), or with the owners and providers of lifelines such as electricity and sewage, we have quantitatively estimated the direct and indirect damage induced by landsliding and this for a 10 to 30 year period (depending on the type of infrastructure or buildings). Economic damage to public infrastructure and buildings was estimated for the entire region, while for private damage 10 cases with severe to small damage were quantified. For example, in the last 10 year, costs of road repair augmented to 814 560 €. Costs to repair damaged roads that have not yet been repaired, were estimated at 669 318 €. In the past 30 years, costs of measures to prevent road damage augmented to at least 14 872 380 €. More than 90% of this budget for preventive measures was spent 30 years ago, when an important freeway was damaged and had to be repaired. These preventive measures (building a grout wall and improving the drainage system) were effective as no further damage has been reported until present. To repair and prevent damage to waterworks and sewage systems, expenditures amounted to 551 044 € and this for the last 30 years. In the past 10 years, a new railway line connecting two important Belgian cities has been built and within that one project, the cost to prevent damage to railroads augmented already to at least 4 567 822 €. The value of real estate located in regions affected by landslides decreased with 15% to 35%. All these damage costs were then used to made potential damage maps. Based on the inventory of landslides, frequency of landslides' re-activation and land use, we categorized regions that are affected by landslides according to their temporal probability of landslide re-activation. This allowed us to produce a (semi-) qualitative risk map for regions that were affected by landslides in the past. This paper shows that, though generally not spectacular, landsliding in low-relief regions susceptible to landslides is a slow but continuously operating process with considerable damage allowing one to identify several medium to high landslide risk zones. As such this study provides important information for government officials, especially those in charge of spatial planning and of town and environmental planning, as it clearly informs about the costs associated with certain land use types in landslide prone areas. This information can be particularly useful for regions in which increasing demand for building land pressures government officials and (local) political leaders to expand the built environment.

  6. Prestraining and Its Influence on Subsequent Fatigue Life

    NASA Technical Reports Server (NTRS)

    Halford, Gary R.; Mcgaw, Michael A.; Kalluri, Sreeramesh

    1995-01-01

    An experimental program was conducted to study the damaging effects of tensile and compressive prestrains on the fatigue life of nickel-base, Inconel 718 superalloy at room temperature. To establish baseline fatigue behavior, virgin specimens with a solid uniform gage section were fatigued to failure under fully-reversed strain-control. Additional specimens were prestrained to 2 percent, 5 percent, and 10 percent (engineering strains) in the tensile direction and to 2 percent (engineering strain) in the compressive direction under stroke-control, and were subsequently fatigued to failure under fully-reversed strain-control. Experimental results are compared with estimates of remaining fatigue lives (after prestraining) using three life prediction approaches: (1) the Linear Damage Rule; (2) the Linear Strain and Life Fraction Rule; and (3) the nonlinear Damage Curve Approach. The Smith-Watson-Topper parameter was used to estimate fatigue lives in the presence of mean stresses. Among the cumulative damage rules investigated, best remaining fatigue life predictions were obtained with the nonlinear Damage Curve Approach.

  7. Lost ecosystem services as a measure of oil spill damages: a conceptual analysis of the importance of baselines.

    PubMed

    Kennedy, Chris J; Cheong, So-Min

    2013-10-15

    The assessment and quantification of damages resulting from marine oil spills is typically coordinated by NOAA, and has historically utilized Habitat Equivalency Analysis (HEA) to estimate damages. Resource economists and others have called for the damage assessment process to instead estimate injuries through the valuation of lost ecosystem services. Our conceptual analysis explores ecosystem service valuation from the perspective of "baselines," which are a fundamental component of both primary and compensatory restoration activities. In practice, baselines have been defined in ecological terms, with minimal consideration of the socioeconomic side of ecosystem service provision. We argue that, for the purposes of scaling compensatory restoration, it is more appropriate to characterize baselines in value terms, thereby integrating non-market valuation approaches from the onset of the damage assessment process. Benefits and challenges of this approach are discussed, along with guidelines for practitioners to identify circumstances in which socioeconomic variables are likely to be important for baseline characterization. Copyright © 2013 Elsevier Ltd. All rights reserved.

  8. CLINICAL AND TREATMENT FEATURES OF OPEN INFECTED FRACTURES IN THE KNEE JOINT REGION IN CONJUNCTION WITH RADIATION SICKNESS (EXPERIMENTAL STUDY)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sakharov, B.V.

    1963-08-01

    Clinical aspects and the course of treatment of open infected fractures in the knee joint region against a background of moderate and severe radiation sickness are discussed. The experiment involved 35 healthy dogs of both sexes. In all, three experiments were involved: on open infected fractures in the knee joint region in conjunction with radiation sickness; open infected fractures in the knee joint region without radiation sickness; radiation sickness without trauma. Infected open injury to the knee joint against a radiation sickness background is a severe affection. The use of delayed surgical and drug treatment (antibiotics, vitamins, antihistamine preparations) affordedmore » survival of at least one-half of the animals. Oral use of phenoxymethyl-penicillin in large doses established in the blood and synovial fluid of the damaged knee joint a therapeutic concentration of antibiotic of long duration (not less than a day). In radiation damage to knee joint accompanied by fracture of the bone fragment, the best method of surgical treatment is osteosynthesis using metal parts. In open infection of a damaged knee joint against a radiation sickness background, even with proper treatment a tendency toward formation of deforming arthrosis was observed. (OTS)« less

  9. Tree-based flood damage modeling of companies: Damage processes and model performance

    NASA Astrophysics Data System (ADS)

    Sieg, Tobias; Vogel, Kristin; Merz, Bruno; Kreibich, Heidi

    2017-07-01

    Reliable flood risk analyses, including the estimation of damage, are an important prerequisite for efficient risk management. However, not much is known about flood damage processes affecting companies. Thus, we conduct a flood damage assessment of companies in Germany with regard to two aspects. First, we identify relevant damage-influencing variables. Second, we assess the prediction performance of the developed damage models with respect to the gain by using an increasing amount of training data and a sector-specific evaluation of the data. Random forests are trained with data from two postevent surveys after flood events occurring in the years 2002 and 2013. For a sector-specific consideration, the data set is split into four subsets corresponding to the manufacturing, commercial, financial, and service sectors. Further, separate models are derived for three different company assets: buildings, equipment, and goods and stock. Calculated variable importance values reveal different variable sets relevant for the damage estimation, indicating significant differences in the damage process for various company sectors and assets. With an increasing number of data used to build the models, prediction errors decrease. Yet the effect is rather small and seems to saturate for a data set size of several hundred observations. In contrast, the prediction improvement achieved by a sector-specific consideration is more distinct, especially for damage to equipment and goods and stock. Consequently, sector-specific data acquisition and a consideration of sector-specific company characteristics in future flood damage assessments is expected to improve the model performance more than a mere increase in data.

  10. Neuro-fuzzy computing for vibration-based damage localization and severity estimation in an experimental wind turbine blade with superimposed operational effects

    NASA Astrophysics Data System (ADS)

    Hoell, Simon; Omenzetter, Piotr

    2016-04-01

    Fueled by increasing demand for carbon neutral energy, erections of ever larger wind turbines (WTs), with WT blades (WTBs) with higher flexibilities and lower buckling capacities lead to increasing operation and maintenance costs. This can be counteracted with efficient structural health monitoring (SHM), which allows scheduling maintenance actions according to the structural state and preventing dramatic failures. The present study proposes a novel multi-step approach for vibration-based structural damage localization and severity estimation for application in operating WTs. First, partial autocorrelation coefficients (PACCs) are estimated from vibrational responses. Second, principal component analysis is applied to PACCs from the healthy structure in order to calculate scores. Then, the scores are ranked with respect to their ability to differentiate different damage scenarios. This ranking information is used for constructing hierarchical adaptive neuro-fuzzy inference systems (HANFISs), where cross-validation is used to identify optimal numbers of hierarchy levels. Different HANFISs are created for the purposes of structural damage localization and severity estimation. For demonstrating the applicability of the approach, experimental data are superimposed with signals from numerical simulations to account for characteristics of operational noise. For the physical experiments, a small scale WTB is excited with a domestic fan and damage scenarios are introduced non-destructively by attaching small masses. Numerical simulations are also performed for a representative fully functional small WT operating in turbulent wind. The obtained results are promising for future applications of vibration-based SHM to facilitate improved safety and reliability of WTs at lower costs.

  11. Objective classification of historical tropical cyclone intensity

    NASA Astrophysics Data System (ADS)

    Chenoweth, Michael

    2007-03-01

    Preinstrumental records of historical tropical cyclone activity require objective methods for accurately categorizing tropical cyclone intensity. Here wind force terms and damage reports from newspaper accounts in the Lesser Antilles and Jamaica for the period 1795-1879 are compared with wind speed estimates calculated from barometric pressure data. A total of 95 separate barometric pressure readings and colocated simultaneous wind force descriptors and wind-induced damage reports are compared. The wind speed estimates from barometric pressure data are taken as the most reliable and serve as a standard to compare against other data. Wind-induced damage reports are used to produce an estimated wind speed range using a modified Fujita scale. Wind force terms are compared with the barometric pressure data to determine if a gale, as used in the contemporary newspapers, is consistent with the modern definition of a gale. Results indicate that the modern definition of a gale (the threshold point separating the classification of a tropical depression from a tropical storm) is equivalent to that in contemporary newspaper accounts. Barometric pressure values are consistent with both reported wind force terms and wind damage on land when the location, speed and direction of movement of the tropical cyclone are determined. Damage reports and derived wind force estimates are consistent with other published results. Biases in ships' logbooks are confirmed and wind force terms of gale strength or greater are identified. These results offer a bridge between the earlier noninstrumental records of tropical cyclones and modern records thereby offering a method of consistently classifying storms in the Caribbean region into tropical depressions, tropical storms, nonmajor and major hurricanes.

  12. Magnetic Flux Leakage Sensing and Artificial Neural Network Pattern Recognition-Based Automated Damage Detection and Quantification for Wire Rope Non-Destructive Evaluation.

    PubMed

    Kim, Ju-Won; Park, Seunghee

    2018-01-02

    In this study, a magnetic flux leakage (MFL) method, known to be a suitable non-destructive evaluation (NDE) method for continuum ferromagnetic structures, was used to detect local damage when inspecting steel wire ropes. To demonstrate the proposed damage detection method through experiments, a multi-channel MFL sensor head was fabricated using a Hall sensor array and magnetic yokes to adapt to the wire rope. To prepare the damaged wire-rope specimens, several different amounts of artificial damages were inflicted on wire ropes. The MFL sensor head was used to scan the damaged specimens to measure the magnetic flux signals. After obtaining the signals, a series of signal processing steps, including the enveloping process based on the Hilbert transform (HT), was performed to better recognize the MFL signals by reducing the unexpected noise. The enveloped signals were then analyzed for objective damage detection by comparing them with a threshold that was established based on the generalized extreme value (GEV) distribution. The detected MFL signals that exceed the threshold were analyzed quantitatively by extracting the magnetic features from the MFL signals. To improve the quantitative analysis, damage indexes based on the relationship between the enveloped MFL signal and the threshold value were also utilized, along with a general damage index for the MFL method. The detected MFL signals for each damage type were quantified by using the proposed damage indexes and the general damage indexes for the MFL method. Finally, an artificial neural network (ANN) based multi-stage pattern recognition method using extracted multi-scale damage indexes was implemented to automatically estimate the severity of the damage. To analyze the reliability of the MFL-based automated wire rope NDE method, the accuracy and reliability were evaluated by comparing the repeatedly estimated damage size and the actual damage size.

  13. Flood damage estimation of companies: A comparison of Stage-Damage-Functions and Random Forests

    NASA Astrophysics Data System (ADS)

    Sieg, Tobias; Kreibich, Heidi; Vogel, Kristin; Merz, Bruno

    2017-04-01

    The development of appropriate flood damage models plays an important role not only for the damage assessment after an event but also to develop adaptation and risk mitigation strategies. So called Stage-Damage-Functions (SDFs) are often applied as a standard approach to estimate flood damage. These functions assign a certain damage to the water depth depending on the use or other characteristics of the exposed objects. Recent studies apply machine learning algorithms like Random Forests (RFs) to model flood damage. These algorithms usually consider more influencing variables and promise to depict a more detailed insight into the damage processes. In addition they provide an inherent validation scheme. Our study focuses on direct, tangible damage of single companies. The objective is to model and validate the flood damage suffered by single companies with SDFs and RFs. The data sets used are taken from two surveys conducted after the floods in the Elbe and Danube catchments in the years 2002 and 2013 in Germany. Damage to buildings (n = 430), equipment (n = 651) as well as goods and stock (n = 530) are taken into account. The model outputs are validated via a comparison with the actual flood damage acquired by the surveys and subsequently compared with each other. This study investigates the gain in model performance with the use of additional data and the advantages and disadvantages of the RFs compared to SDFs. RFs show an increase in model performance with an increasing amount of data records over a comparatively large range, while the model performance of the SDFs is already saturated for a small set of records. In addition, the RFs are able to identify damage influencing variables, which improves the understanding of damage processes. Hence, RFs can slightly improve flood damage predictions and provide additional insight into the underlying mechanisms compared to SDFs.

  14. Arboreal seed removal and insect damage in three California oaks

    Treesearch

    Walter D. Koenig; Johannes M. H. Knops; William J. Carmen

    2002-01-01

    We investigated arboreal removal and insect damage to acorns in an undisturbed oak woodland in central coastal California. Arboreal seed removal was determined for four to eight individual Quercus lobata trees over a period of 14 years by comparing visual estimates of the acorn crop with the number of acorns caught in seed traps. Insect damage was...

  15. Strength loss in southern pine poles damaged by woodpeckers

    Treesearch

    R.W. Rumsey; G.E. Woodson

    1973-01-01

    Woodpecker damage caused extensive reductions in strength of 50-foot, class-2 utility poles, the amount depending on the cross-sectional area of wood removed and its distance from the apex. Two methods for estimating when damaged poles should be replaced proved to be conservative when applied to results of field tests. Such conservative predictions of falling loads...

  16. Strength loss in southern pine poles damaged by woodpeckers

    Treesearch

    R.L. Rumsey; George E. Woodson

    1973-01-01

    Woodpecker damage caused extensive reductions in strength of 50-foot, class-2 utility poles, the amount depending on the cross-sectional area of wood removed and its distance from the apex. Two methods for estimating when damaged poles should be replaced proved to be conservative when applied to results of field rests. Such conservative predictions of failing loads...

  17. Estimation of potential impacts and natural resource damages of oil.

    PubMed

    McCay, Deborah French; Rowe, Jill Jennings; Whittier, Nicole; Sankaranarayanan, Sankar; Etkin, Dagmar Schmidt

    2004-02-27

    Methods were developed to estimate the potential impacts and natural resource damages resulting from oil spills using probabilistic modeling techniques. The oil fates model uses wind data, current data, and transport and weathering algorithms to calculate mass balance of fuel components in various environmental compartments (water surface, shoreline, water column, atmosphere, sediments, etc.), oil pathway over time (trajectory), surface distribution, shoreline oiling, and concentrations of the fuel components in water and sediments. Exposure of aquatic habitats and organisms to whole oil and toxic components is estimated in the biological model, followed by estimation of resulting acute mortality and ecological losses. Natural resource damages are based on estimated costs to restore equivalent resources and/or ecological services, using Habitat Equivalency Analysis (HEA) and Resource Equivalency Analysis (REA) methods. Oil spill modeling was performed for two spill sites in central San Francisco Bay, three spill sizes (20th, 50th, and 95th percentile volumes from tankers and larger freight vessels, based on an analysis of likely spill volumes given a spill has occurred) and four oil types (gasoline, diesel, heavy fuel oil, and crude oil). The scenarios were run in stochastic mode to determine the frequency distribution, mean and standard deviation of fates, impacts, and damages. This work is significant as it demonstrates a statistically quantifiable method for estimating potential impacts and financial consequences that may be used in ecological risk assessment and cost-benefit analyses. The statistically-defined spill volumes and consequences provide an objective measure of the magnitude, range and variability of impacts to wildlife, aquatic organisms and shorelines for potential spills of four oil/fuel types, each having distinct environmental fates and effects.

  18. A framework for global river flood risk assessments

    NASA Astrophysics Data System (ADS)

    Winsemius, H. C.; Van Beek, L. P. H.; Jongman, B.; Ward, P. J.; Bouwman, A.

    2012-08-01

    There is an increasing need for strategic global assessments of flood risks in current and future conditions. In this paper, we propose a framework for global flood risk assessment for river floods, which can be applied in current conditions, as well as in future conditions due to climate and socio-economic changes. The framework's goal is to establish flood hazard and impact estimates at a high enough resolution to allow for their combination into a risk estimate. The framework estimates hazard at high resolution (~1 km2) using global forcing datasets of the current (or in scenario mode, future) climate, a global hydrological model, a global flood routing model, and importantly, a flood extent downscaling routine. The second component of the framework combines hazard with flood impact models at the same resolution (e.g. damage, affected GDP, and affected population) to establish indicators for flood risk (e.g. annual expected damage, affected GDP, and affected population). The framework has been applied using the global hydrological model PCR-GLOBWB, which includes an optional global flood routing model DynRout, combined with scenarios from the Integrated Model to Assess the Global Environment (IMAGE). We performed downscaling of the hazard probability distributions to 1 km2 resolution with a new downscaling algorithm, applied on Bangladesh as a first case-study application area. We demonstrate the risk assessment approach in Bangladesh based on GDP per capita data, population, and land use maps for 2010 and 2050. Validation of the hazard and damage estimates has been performed using the Dartmouth Flood Observatory database and damage estimates from the EM-DAT database and World Bank sources. We discuss and show sensitivities of the estimated risks with regard to the use of different climate input sets, decisions made in the downscaling algorithm, and different approaches to establish impact models.

  19. A modified cluster-sampling method for post-disaster rapid assessment of needs.

    PubMed Central

    Malilay, J.; Flanders, W. D.; Brogan, D.

    1996-01-01

    The cluster-sampling method can be used to conduct rapid assessment of health and other needs in communities affected by natural disasters. It is modelled on WHO's Expanded Programme on Immunization method of estimating immunization coverage, but has been modified to provide (1) estimates of the population remaining in an area, and (2) estimates of the number of people in the post-disaster area with specific needs. This approach differs from that used previously in other disasters where rapid needs assessments only estimated the proportion of the population with specific needs. We propose a modified n x k survey design to estimate the remaining population, severity of damage, the proportion and number of people with specific needs, the number of damaged or destroyed and remaining housing units, and the changes in these estimates over a period of time as part of the survey. PMID:8823962

  20. Social tension as precursor of large damaging earthquake: legend or reality?

    NASA Astrophysics Data System (ADS)

    Molchanov, O.

    2008-11-01

    Using case study of earthquake (EQ) activity and war conflicts in Caucasus during 1975 2002 time interval and correlation analysis of global distribution of damaging EQs and war-related social tension during 1901 2005 period we conclude:

    • There is a statistically reliable increase of social tension several years (or several months in case study) before damaging EQs,
    • There is evident decrease of social tension several years after damaging EQs, probably due to society consolidation,
    • Preseismic effect is absent for the large EQs in unpopulated areas,
    • There is some factual background for legendary belief in Almighty retribution for social abnormal behavior.

  1. Impact damage in composite plates

    NASA Technical Reports Server (NTRS)

    Shahid, I.; Lee, S.; Chang, F. K.; Shah, B. M.

    1995-01-01

    The objective of this research paper was to link two computer codes, PDCOMP (for Progressive Damage Analysis for Laminated Composites) and 3DIMPACT (for the prediction of the extent of delaminations in laminated composites resulting from point impact loads), in order to predict impact damage by taking into account local damage and material degradation and to estimate residual stiffness of composites after impact. The resulting graphs and analysis versus test results are presented along with the conclusive results of the codes' performances.

  2. Variability in wood-frame building damage using broad-band synthetic ground motions: a comparative numerical study with recorded motions

    USGS Publications Warehouse

    Pei, Shiling; van de Lindt, John W.; Hartzell, Stephen; Luco, Nicolas

    2014-01-01

    Earthquake damage to light-frame wood buildings is a major concern for North America because of the volume of this construction type. In order to estimate wood building damage using synthetic ground motions, we need to verify the ability of synthetically generated ground motions to simulate realistic damage for this structure type. Through a calibrated damage potential indicator, four different synthetic ground motion models are compared with the historically recorded ground motions at corresponding sites. We conclude that damage for sites farther from the fault (>20 km) is under-predicted on average and damage at closer sites is sometimes over-predicted.

  3. The economic costs of alcohol consumption in Thailand, 2006

    PubMed Central

    2010-01-01

    Background There is evidence that the adverse consequences of alcohol impose a substantial economic burden on societies worldwide. Given the lack of generalizability of study results across different settings, many attempts have been made to estimate the economic costs of alcohol for various settings; however, these have mostly been confined to industrialized countries. To our knowledge, there are a very limited number of well-designed studies which estimate the economic costs of alcohol consumption in developing countries, including Thailand. Therefore, this study aims to estimate these economic costs, in Thailand, 2006. Methods This is a prevalence-based, cost-of-illness study. The estimated costs in this study included both direct and indirect costs. Direct costs included health care costs, costs of law enforcement, and costs of property damage due to road-traffic accidents. Indirect costs included costs of productivity loss due to premature mortality, and costs of reduced productivity due to absenteeism and presenteeism (reduced on-the-job productivity). Results The total economic cost of alcohol consumption in Thailand in 2006 was estimated at 156,105.4 million baht (9,627 million US$ PPP) or about 1.99% of the total Gross Domestic Product (GDP). Indirect costs outweigh direct costs, representing 96% of the total cost. The largest cost attributable to alcohol consumption is that of productivity loss due to premature mortality (104,128 million baht/6,422 million US$ PPP), followed by cost of productivity loss due to reduced productivity (45,464.6 million baht/2,804 million US$ PPP), health care cost (5,491.2 million baht/339 million US$ PPP), cost of property damage as a result of road traffic accidents (779.4 million baht/48 million US$ PPP), and cost of law enforcement (242.4 million baht/15 million US$ PPP), respectively. The results from the sensitivity analysis revealed that the cost ranges from 115,160.4 million baht to 214,053.0 million baht (7,102.1 - 13,201 million US$ PPP) depending on the methods and assumptions employed. Conclusions Alcohol imposes a substantial economic burden on Thai society, and according to these findings, the Thai government needs to pay significantly more attention to implementing more effective alcohol policies/interventions in order to reduce the negative consequences associated with alcohol. PMID:20534112

  4. VERDE Analytic Modules

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    2008-01-15

    The Verde Analytic Modules permit the user to ingest openly available data feeds about phenomenology (storm tracks, wind, precipitation, earthquake, wildfires, and similar natural and manmade power grid disruptions and forecast power outages, restoration times, customers outaged, and key facilities that will lose power. Damage areas are predicted using historic damage criteria of the affected area. The modules use a cellular automata approach to estimating the distribution circuits assigned to geo-located substations. Population estimates served within the service areas are located within 1 km grid cells and converted to customer counts by conversion through demographic estimation of households and commercialmore » firms within the population cells. Restoration times are estimated by agent-based simulation of restoration crews working according to utility published prioritization calibrated by historic performance.« less

  5. Effects of Flood Control Works Failure in the Missouri River Basin

    DTIC Science & Technology

    2014-06-13

    Project (“BSNP”). Specifically, in order to restore habitat of certain native species in the Missouri River Basin (“the Basin”), the Corps departed...estimated that over $654 million in damages occurred to agricultural and rural areas (U.S. Army Corps of Engineers 1995, 5-5). There was over $65 million...USACE Kansas City District’s civil works boundary, flooding resulted in estimated damages of greater than $2.2 billion, with agricultural and rural

  6. A time-dependent probabilistic seismic-hazard model for California

    USGS Publications Warehouse

    Cramer, C.H.; Petersen, M.D.; Cao, T.; Toppozada, Tousson R.; Reichle, M.

    2000-01-01

    For the purpose of sensitivity testing and illuminating nonconsensus components of time-dependent models, the California Department of Conservation, Division of Mines and Geology (CDMG) has assembled a time-dependent version of its statewide probabilistic seismic hazard (PSH) model for California. The model incorporates available consensus information from within the earth-science community, except for a few faults or fault segments where consensus information is not available. For these latter faults, published information has been incorporated into the model. As in the 1996 CDMG/U.S. Geological Survey (USGS) model, the time-dependent models incorporate three multisegment ruptures: a 1906, an 1857, and a southern San Andreas earthquake. Sensitivity tests are presented to show the effect on hazard and expected damage estimates of (1) intrinsic (aleatory) sigma, (2) multisegment (cascade) vs. independent segment (no cascade) ruptures, and (3) time-dependence vs. time-independence. Results indicate that (1) differences in hazard and expected damage estimates between time-dependent and independent models increase with decreasing intrinsic sigma, (2) differences in hazard and expected damage estimates between full cascading and not cascading are insensitive to intrinsic sigma, (3) differences in hazard increase with increasing return period (decreasing probability of occurrence), and (4) differences in moment-rate budgets increase with decreasing intrinsic sigma and with the degree of cascading, but are within the expected uncertainty in PSH time-dependent modeling and do not always significantly affect hazard and expected damage estimates.

  7. Endothelial Cell Bioenergetics and Mitochondrial DNA Damage Differ in Humans Having African or West Eurasian Maternal Ancestry

    PubMed Central

    Krzywanski, David M.; Moellering, Douglas R.; Westbrook, David G.; Dunham-Snary, Kimberly J.; Brown, Jamelle; Bray, Alexander W.; Feeley, Kyle P.; Sammy, Melissa J.; Smith, Matthew R.; Schurr, Theodore G.; Vita, Joseph A.; Ambalavanan, Namasivayam; Calhoun, David; Dell’Italia, Louis; Ballinger, Scott W.

    2016-01-01

    Background We hypothesized that endothelial cells having distinct mitochondrial genetic backgrounds would show variation in mitochondrial function and oxidative stress markers concordant with known differential cardiovascular disease susceptibilities. To test this hypothesis, mitochondrial bioenergetics were determined in endothelial cells from healthy individuals with African versus European maternal ancestries. Methods and Results Bioenergetics and mitochondrial DNA (mtDNA) damage were assessed in single donor human umbilical vein endothelial cells (HUVECs) belonging to mtDNA haplogroups H and L, representing West Eurasian and African maternal ancestry, respectively. HUVECs from haplogroup L utilized less oxygen for ATP production and had increased levels of mtDNA damage compared to those in haplogroup H. Differences in bioenergetic capacity were also observed in that HUVECs belonging to haplogroup L had decreased maximal bioenergetic capacities compared to haplogroup H. Analysis of peripheral blood mononuclear cells from age-matched healthy controls with West Eurasian or African maternal ancestries showed that haplogroups sharing an A to G mtDNA mutation at nucleotide pair (np) 10,398 had increased mtDNA damage compared to those lacking this mutation. Further study of angiographically proven coronary artery disease patients and age-matched healthy controls revealed that mtDNA damage was associated with vascular function and remodeling, and that age of disease onset was later in individuals from haplogroups lacking the A to G mutation at np 10,398. Conclusions Differences in mitochondrial bioenergetics and mtDNA damage associated with maternal ancestry may contribute to endothelial dysfunction and vascular disease. PMID:26787433

  8. Assessing the Social and Environmental Costs of Institutional ...

    EPA Pesticide Factsheets

    We estimate the damage costs associated with the institutional nitrogen (N) footprint and explore how this information could be used to create more sustainable institutions. Potential damages associated with the release of NOx and N2O to air and release of N to water were estimated using a cost per unit N approach. Annual potential damage costs to human health, agriculture and natural ecosystems associated with the N footprint of institutions were $10.5 million USD (2014) at the University of Virginia (UVA) and $3.04 million at the University of New Hampshire (UNH). Costs associated with the release of nitrogen oxides (NOx) to human health, in particular the use of coal-derived energy, were the largest component of damage at UVA. At UNH the energy N footprint is much lower because of a co-generation source, and thus the majority of damages were associated with food production. Annual damages associated with release of N from food production were very similar at the two universities ($1.37 vs. $1.66 million at UVA and UNH respectively). These damages also have implications for the extent and scale at which the damages are felt. For example, impacts to human health from energy and transportation are generally larger near the power plants and roads, while impacts from food production can be distant from the campus. Making this information available to institutions can improve their understanding of the damages associated with the different N forms and sourc

  9. Analysis of neutron spectrum effects on primary damage in tritium breeding blankets

    NASA Astrophysics Data System (ADS)

    Choi, Yong Hee; Joo, Han Gyu

    2012-07-01

    The effect of neutron spectrum on primary damages in a structural material of a tritium breeding blanket is investigated with a newly established recoil spectrum estimation system. First, a recoil spectrum generation code is developed to obtain the energy spectrum of primary knock-on atoms (PKAs) for a given neutron spectrum utilizing the latest ENDF/B data. Secondly, a method for approximating the high energy tail of the recoil spectrum is introduced to avoid expensive molecular dynamics calculations for high energy PKAs using the concept of recoil energy of the secondary knock-on atoms originated by the INtegration of CAScades (INCAS) model. Thirdly, the modified spectrum is combined with a set of molecular dynamics calculation results to estimate the primary damage parameters such as the number of surviving point defects. Finally, the neutron spectrum is varied by changing the material of the spectral shifter and the result in primary damage parameters is examined.

  10. New method for estimating clustering of DNA lesions induced by physical/chemical mutagens using fluorescence anisotropy.

    PubMed

    Akamatsu, Ken; Shikazono, Naoya; Saito, Takeshi

    2017-11-01

    We have developed a new method for estimating the localization of DNA damage such as apurinic/apyrimidinic sites (APs) on DNA using fluorescence anisotropy. This method is aimed at characterizing clustered DNA damage produced by DNA-damaging agents such as ionizing radiation and genotoxic chemicals. A fluorescent probe with an aminooxy group (AlexaFluor488) was used to label APs. We prepared a pUC19 plasmid with APs by heating under acidic conditions as a model for damaged DNA, and subsequently labeled the APs. We found that the observed fluorescence anisotropy (r obs ) decreases as averaged AP density (λ AP : number of APs per base pair) increases due to homo-FRET, and that the APs were randomly distributed. We applied this method to three DNA-damaging agents, 60 Co γ-rays, methyl methanesulfonate (MMS), and neocarzinostatin (NCS). We found that r obs -λ AP relationships differed significantly between MMS and NCS. At low AP density (λ AP  < 0.001), the APs induced by MMS seemed to not be closely distributed, whereas those induced by NCS were remarkably clustered. In contrast, the AP clustering induced by 60 Co γ-rays was similar to, but potentially more likely to occur than, random distribution. This simple method can be used to estimate mutagenicity of ionizing radiation and genotoxic chemicals. Copyright © 2017 Elsevier Inc. All rights reserved.

  11. A comparative evaluation of piezoelectric sensors for acoustic emission-based impact location estimation and damage classification in composite structures

    NASA Astrophysics Data System (ADS)

    Uprety, Bibhisha; Kim, Sungwon; Mathews, V. John; Adams, Daniel O.

    2015-03-01

    Acoustic Emission (AE) based Structural Health Monitoring (SHM) is of great interest for detecting impact damage in composite structures. Within the aerospace industry the need to detect and locate these events, even when no visible damage is present, is important both from the maintenance and design perspectives. In this investigation, four commercially available piezoelectric sensors were evaluated for usage in an AE-based SHM system. Of particular interest was comparing the acoustic response of the candidate piezoelectric sensors for impact location estimations as well as damage classification resulting from the impact in fiber-reinforced composite structures. Sensor assessment was performed based on response signal characterization and performance for active testing at 300 kHz and steel-ball drop testing using both aluminum and carbon/epoxy composite plates. Wave mode velocities calculated from the measured arrival times were found to be in good agreement with predictions obtained using both the Disperse code and finite element analysis. Differences in the relative strength of the received wave modes, the overall signal strengths and signal-to-noise ratios were observed through the use of both active testing as well as passive steel-ball drop testing. Further comparative is focusing on assessing AE sensor performance for use in impact location estimation algorithms as well as detecting and classifying damage produced in composite structures due to impact events.

  12. Frequency of dicentrics and contamination levels in Ukrainian children and adolescents from areas near Chernobyl 20 years after the nuclear plant accident.

    PubMed

    Montoro, Alegría; Sebastià, Natividad; Candela-Juan, Cristian; Barquinero, Joan Francesc; Soriano, José Miguel; Almonacid, Miguel; Alonso, Oscar; Guasp, Miguel; Marques-Sule, Elena; Cervera, José; Such, Esperanza; Arnal, Clara; Villaescusa, Juan Ignacio

    2013-11-01

    To survey the possible presence of chromosomal damage and internal contamination in a group of Ukrainian children and adolescents, 20 years after the Chernobyl accident at the Nuclear Power Plant. Cytogenetical procedures were performed according to dicentric assay in 55 Ukrainian children and adolescents (29 boys and 26 girls), living near Chernobyl. In addition, a whole body detector and urinalysis were used to detect internal contamination. 36 dicentrics were found in a total of 53,477 metaphases scored in these children, which reflected a frequency of dicentrics below the background level. On the other hand, internal contamination was not detected in any subject studied. Since the estimated absorbed dose is below the detection limit, according to both biological and physical dosimetry, radiation overexposure during the last 3-5 years has not been detected in the considered subjects.

  13. Using damage data to estimate the risk from summer convective precipitation extremes

    NASA Astrophysics Data System (ADS)

    Schroeer, Katharina; Tye, Mari

    2017-04-01

    This study explores the potential added value from including loss and damage data to understand the risks from high-intensity short-duration convective precipitation events. Projected increases in these events are expected even in regions that are likely to become more arid. Such high intensity precipitation events can trigger hazardous flash floods, debris flows, and landslides that put people and local assets at risk. However, the assessment of local scale precipitation extremes is hampered by its high spatial and temporal variability. In addition to this, not only are extreme events rare, but such small-scale events are likely to be underreported where they do not coincide with the observation network. Reports of private loss and damage on a local administrative unit scale (LAU 2 level) are used to explore the relationship between observed rainfall events and damages reportedly related to hydro-meteorological processes. With 480 Austrian municipalities located within our south-eastern Alpine study region, the damage data are available on a much smaller scale than the available rainfall data. Precipitation is recorded daily at 185 gauges and 52% of these stations additionally deliver sub-hourly rainfall information. To obtain physically plausible information, damage and rainfall data are grouped and analyzed on a catchment scale. The data indicate that rainfall intensities are higher on days that coincide with a damage claim than on days for which no damage was reported. However, approximately one third of the damages related to hydro-meteorological hazards were claimed on days for which no rainfall was recorded at any gauge in the respective catchment. Our goal is to assess whether these events indicate potential extreme events missing in the observations. Damage always is a consequence of an asset being exposed and susceptible to a hazardous process, and naturally, many factors influence whether an extreme rainfall event causes damage. We set up a statistical model to test whether the relationship between extreme rainfall events and damages is robust enough to estimate a potential underrepresentation of high intensity rainfall events in ungauged areas. Risk-relevant factors of socio-economic vulnerability, land cover, streamflow data, and weather type information are included to improve and sharpen the analysis. Within this study, we first aim to identify which rainfall events are most damaging and which factors affect the damages - seen as a proxy for the vulnerability - related to summer convective rainfall extremes in different catchment types. Secondly, we aim to detect potentially unreported damaging rainfall events and estimate the likelihood of such cases. We anticipate this damage perspective on summertime extreme convective precipitation to be beneficial for risk assessment, uncertainty management, and decision making with respect to weather and climate extremes on the regional-to-local level.

  14. 46 CFR 171.080 - Damage stability standards for vessels with Type I or Type II subdivision.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... to which the vessel heels after sustained damage, are swung out if necessary, fully loaded and ready...; and (C) Survival craft on the side of the vessel opposite that to which the vessel heels remain stowed... damage occurs. (3) The estimated maximum angle of heel before equalization must be approved by the...

  15. Rapid assessment of wildfire damage using Forest Inventory data: A case in Georgia

    Treesearch

    Richard A. Harper; John W. Coulsten; Jeffery A. Turner

    2009-01-01

    The rapid assessment of damage caused by natural disasters is essential for planning the appropriate amount of disaster relief funds and public communication. Annual Forest Inventory and Analysis (FIA) data provided initial estimates of damage to timberland in a timely manner to State leaders during the 2007 Georgia Bay Complex Wildfire in southeast Georgia. FIA plots...

  16. Earthquake Damage Assessment over Port-au-Prince (Haiti) by Fusing Optical and SAR Data

    NASA Astrophysics Data System (ADS)

    Romaniello, V.; Piscini, A.; Bignami, C.; Anniballe, R.; Pierdicca, N.; Stramondo, S.

    2016-08-01

    This work proposes methodologies aiming at evaluating the sensitivity of optical and SAR change features obtained from satellite images with respect to the damage grade. The proposed methods are derived from the literature ([1], [2], [3], [4]) and the main novelty concerns the estimation of these change features at object scale.The test case is the Mw 7.0 earthquake that hit Haiti on January 12, 2010.The analysis of change detection indicators is based on ground truth information collected during a post- earthquake survey. We have generated the damage map of Port-au-Prince by considering a set of polygons extracted from the open source Open Street Map geo- database. The resulting damage map was calculated in terms of collapse ratio [5].We selected some features having a good sensitivity with damage at object scale [6]: the Normalised Difference Index, the Kullback-Libler Divergence, the Mutual Information and the Intensity Correlation Difference.The Naive Bayes and the Support Vector Machine classifiers were used to evaluate the goodness of these features. The classification results demonstrate that the simultaneous use of several change features from EO observations can improve the damage estimation at object scale.

  17. An Account of Preliminary Landslide Damage and Losses Resulting from the February 28, 2001, Nisqually, Washington, Earthquake

    USGS Publications Warehouse

    Highland, Lynn M.

    2003-01-01

    The February 28, 2001, Nisqually, Washington, earthquake (Mw = 6.8) damaged an area of the northwestern United States that previously experienced two major historical earthquakes, in 1949 and in 1965. Preliminary estimates of direct monetary losses from damage due to earthquake-induced landslides is approximately $34.3 million. However, this figure does not include costs from damages to the elevated portion of the Alaskan Way Viaduct, a major highway through downtown Seattle, Washington that will be repaired or rebuilt, depending on the future decision of local and state authorities. There is much debate as to the cause of the damage to this viaduct with evaluations of cause ranging from earthquake shaking and liquefaction to lateral spreading to a combination of these effects. If the viaduct is included in the costs, the losses increase to $500+ million (if it is repaired) or to more than $1+ billion (if it is replaced). Preliminary estimate of losses due to all causes of earthquake damage is approximately $2 billion, which includes temporary repairs to the Alaskan Way Viaduct. These preliminary dollar figures will no doubt increase when plans and decisions regarding the Viaduct are completed.

  18. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kolaczkowski, A.M.; Lambright, J.A.; Ferrell, W.L.

    This document contains the internal event initiated accident sequence analyses for Peach Bottom, Unit 2; one of the reference plants being examined as part of the NUREG-1150 effort by the Nuclear Regulatory Commission. NUREG-1150 will document the risk of a selected group of nuclear power plants. As part of that work, this report contains the overall core damage frequency estimate for Peach Bottom, Unit 2, and the accompanying plant damage state frequencies. Sensitivity and uncertainty analyses provided additional insights regarding the dominant contributors to the Peach Bottom core damage frequency estimate. The mean core damage frequency at Peach Bottom wasmore » calculated to be 8.2E-6. Station blackout type accidents (loss of all ac power) were found to dominate the overall results. Anticipated Transient Without Scram accidents were also found to be non-negligible contributors. The numerical results are largely driven by common mode failure probability estimates and to some extent, human error. Because of significant data and analysis uncertainties in these two areas (important, for instance, to the most dominant scenario in this study), it is recommended that the results of the uncertainty and sensitivity analyses be considered before any actions are taken based on this analysis.« less

  19. Chromosome territories reposition during DNA damage-repair response

    PubMed Central

    2013-01-01

    Background Local higher-order chromatin structure, dynamics and composition of the DNA are known to determine double-strand break frequencies and the efficiency of repair. However, how DNA damage response affects the spatial organization of chromosome territories is still unexplored. Results Our report investigates the effect of DNA damage on the spatial organization of chromosome territories within interphase nuclei of human cells. We show that DNA damage induces a large-scale spatial repositioning of chromosome territories that are relatively gene dense. This response is dose dependent, and involves territories moving from the nuclear interior to the periphery and vice versa. Furthermore, we have found that chromosome territory repositioning is contingent upon double-strand break recognition and damage sensing. Importantly, our results suggest that this is a reversible process where, following repair, chromosome territories re-occupy positions similar to those in undamaged control cells. Conclusions Thus, our report for the first time highlights DNA damage-dependent spatial reorganization of whole chromosomes, which might be an integral aspect of cellular damage response. PMID:24330859

  20. Estimating externalities of biomass fuel cycles, Report 7

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Barnthouse, L.W.; Cada, G.F.; Cheng, M.-D.

    1998-01-01

    This report documents the analysis of the biomass fuel cycle, in which biomass is combusted to produce electricity. The major objectives of this study were: (1) to implement the methodological concepts which were developed in the Background Document (ORNL/RFF 1992) as a means of estimating the external costs and benefits of fuel cycles, and by so doing, to demonstrate their application to the biomass fuel cycle; (2) to develop, given the time and resources, a range of estimates of marginal (i.e., the additional or incremental) damages and benefits associated with selected impact-pathways from a new wood-fired power plant, using amore » representative benchmark technology, at two reference sites in the US; and (3) to assess the state of the information available to support energy decision making and the estimation of externalities, and by so doing, to assist in identifying gaps in knowledge and in setting future research agendas. The demonstration of methods, modeling procedures, and use of scientific information was the most important objective of this study. It provides an illustrative example for those who will, in the future, undertake studies of actual energy options and sites. As in most studies, a more comprehensive analysis could have been completed had budget constraints not been as severe. Particularly affected were the air and water transport modeling, estimation of ecological impacts, and economic valuation. However, the most important objective of the study was to demonstrate methods, as a detailed example for future studies. Thus, having severe budget constraints was appropriate from the standpoint that these studies could also face similar constraints. Consequently, an important result of this study is an indication of what can be done in such studies, rather than the specific numerical estimates themselves.« less

  1. Future respiratory hospital admissions from wildfire smoke under climate change in the Western US

    NASA Astrophysics Data System (ADS)

    Coco Liu, Jia; Mickley, Loretta J.; Sulprizio, Melissa P.; Yue, Xu; Peng, Roger D.; Dominici, Francesca; Bell, Michelle L.

    2016-12-01

    Background. Wildfires are anticipated to be more frequent and intense under climate change. As a result, wildfires may emit more air pollutants that can harm health in communities in the future. The health impacts of wildfire smoke under climate change are largely unknown. Methods. We linked projections of future levels of fine particulate matter (PM2.5) specifically from wildfire smoke under the A1B climate change scenario using the GEOS-Chem model for 2046-2051, present-day estimates of hospital admission impacts from wildfire smoke, and future population projections to estimate the change in respiratory hospital admissions for persons ≥65 years by county (n = 561) from wildfire PM2.5 under climate change in the Western US. Results. The increase in intense wildfire smoke days from climate change would result in an estimated 178 (95% confidence interval: 6.2, 361) additional respiratory hospital admissions in the Western US, accounting for estimated future increase in the elderly population. Climate change is estimated to impose an additional 4990 high-pollution smoke days. Central Colorado, Washington and southern California are estimated to experience the highest percentage increase in respiratory admissions from wildfire smoke under climate change. Conclusion. Although the increase in number of respiratory admissions from wildfire smoke seems modest, these results provide important scientific evidence of an often-ignored aspect of wildfire impact, and information on their anticipated spatial distribution. Wildfires can cause serious social burdens such as property damage and suppression cost, but can also raise health problems. The results provide information that can be incorporated into development of environmental and health policies in response to climate change. Climate change adaptation policies could incorporate scientific evidence on health risks from natural disasters such as wildfires.

  2. Estimating the Number of Low-Income Americans Exposed to Household Air Pollution from Burning Solid Fuels

    PubMed Central

    Rogalsky, Derek K.; Mendola, Pauline; Metts, Tricia A.

    2014-01-01

    Background: Exposure to household air pollution (HAP) from inefficient biomass and coal stoves kills nearly 4 million people every year worldwide. HAP is an environmental risk associated with poverty that affects an estimated 3 billion people mostly in low- and middle-income countries. Objectives: Our goal was to estimate the number of low-income Americans exposed to potentially health-damaging concentrations of HAP. Methods: We mapped county-level data for the percentage of households using wood, coal, and/or coke as their primary heating fuel along with percent of the population below the federal poverty level. Using U.S. Census data and the likelihood of fugitive emissions as reported in the literature, we estimated the number of low-income Americans potentially exposed to HAP. Results: Solid fuel is the primary heating source for > 2.5 million U.S. households, or 6.5 million people. The mapping exercise showed several rural areas, primarily in the northern and western regions, that have high levels of solid-fuel use and poverty. We then identified 117 counties with high co-incident poverty and solid-fuel use as high-priority counties for research into potential health risks from HAP. We estimate that between 500,000 and 600,000 low-income people in the United States are likely exposed to HAP from burning solid fuels within their homes. Conclusion: HAP occurs within the United States and should be further investigated for adverse health risks, especially among those living in areas with rural poverty. Citation: Rogalsky DK, Mendola P, Metts TA, Martin WJ II. 2014. Estimating the number of low-income Americans exposed to household air pollution from burning solid fuels. Environ Health Perspect 122:806–810; http://dx.doi.org/10.1289/ehp.1306709 PMID:24833615

  3. Using Integrated Assessment Models to Estimate the Economic Damages from Temperature Related Human Health Effects in the US

    NASA Astrophysics Data System (ADS)

    Gilmore, E.; Calvin, K. V.; Puett, R.; Sapkota, A.; Schwarber, A.

    2014-12-01

    Climate change is projected to increase risks to human health. One pathway that may be particularly difficult to manage is adverse human health impacts (e.g. premature mortality and morbidity) from increases in mean temperatures and changing patterns of temperature extremes. Modeling how these health risks evolve over decadal time-scales is challenging as the severity of the impacts depends on changes in climate as well as socioeconomic conditions. Here, we show estimates of health damages as well as both direct and indirect economic damages that span climate and socioeconomic dimensions for each US state to 2050. We achieve this objective by extending the integrated assessment model (IAM), Global Change Assessment Model (GCAM-USA). First, we quantify the change in premature mortality. We identify a range of exposure-response relationships for temperature related mortality through a critical review of the literature. We then implement these relationships in the GCAM by coupling them with projections of future temperature patterns and population estimates. Second, we monetize the effect of these adverse health effects, including both direct and indirect economic costs through labor force participation and productivity along a range of possible economic pathways. Finally, we evaluate how uncertainty in the parameters and assumptions affects the range of possible estimates. We conclude that the model is sensitive to assumptions regarding exposure-response relationship and population growth. The economic damages, however, are driven by the estimates of income and GDP growth as well as the potential for adaptation measures, namely the use and effectiveness of air conditioning.

  4. Knowledge base about earthquakes as a tool to minimize strong events consequences

    NASA Astrophysics Data System (ADS)

    Frolova, Nina; Bonnin, Jean; Larionov, Valery; Ugarov, Alexander; Kijko, Andrzej

    2017-04-01

    The paper describes the structure and content of the knowledge base on physical and socio-economical consequences of damaging earthquakes, which may be used for calibration of near real-time loss assessment systems based on simulation models for shaking intensity, damage to buildings and casualties estimates. Such calibration allows to compensate some factors which influence on reliability of expected damage and loss assessment in "emergency" mode. The knowledge base contains the description of past earthquakes' consequences for the area under study. It also includes the current distribution of built environment and population at the time of event occurrence. Computer simulation of the recorded in knowledge base events allow to determine the sets of regional calibration coefficients, including rating of seismological surveys, peculiarities of shaking intensity attenuation and changes in building stock and population distribution, in order to provide minimum error of damaging earthquakes loss estimations in "emergency" mode. References 1. Larionov, V., Frolova, N: Peculiarities of seismic vulnerability estimations. In: Natural Hazards in Russia, volume 6: Natural Risks Assessment and Management, Publishing House "Kruk", Moscow, 120-131, 2003. 2. Frolova, N., Larionov, V., Bonnin, J.: Data Bases Used In Worlwide Systems For Earthquake Loss Estimation In Emergency Mode: Wenchuan Earthquake. In Proc. TIEMS2010 Conference, Beijing, China, 2010. 3. Frolova N. I., Larionov V. I., Bonnin J., Sushchev S. P., Ugarov A. N., Kozlov M. A. Loss Caused by Earthquakes: Rapid Estimates. Natural Hazards Journal of the International Society for the Prevention and Mitigation of Natural Hazards, vol.84, ISSN 0921-030, Nat Hazards DOI 10.1007/s11069-016-2653

  5. A coupled weather generator - rainfall-runoff approach on hourly time steps for flood risk analysis

    NASA Astrophysics Data System (ADS)

    Winter, Benjamin; Schneeberger, Klaus; Dung Nguyen, Viet; Vorogushyn, Sergiy; Huttenlau, Matthias; Merz, Bruno; Stötter, Johann

    2017-04-01

    The evaluation of potential monetary damage of flooding is an essential part of flood risk management. One possibility to estimate the monetary risk is to analyze long time series of observed flood events and their corresponding damages. In reality, however, only few flood events are documented. This limitation can be overcome by the generation of a set of synthetic, physically and spatial plausible flood events and subsequently the estimation of the resulting monetary damages. In the present work, a set of synthetic flood events is generated by a continuous rainfall-runoff simulation in combination with a coupled weather generator and temporal disaggregation procedure for the study area of Vorarlberg (Austria). Most flood risk studies focus on daily time steps, however, the mesoscale alpine study area is characterized by short concentration times, leading to large differences between daily mean and daily maximum discharge. Accordingly, an hourly time step is needed for the simulations. The hourly metrological input for the rainfall-runoff model is generated in a two-step approach. A synthetic daily dataset is generated by a multivariate and multisite weather generator and subsequently disaggregated to hourly time steps with a k-Nearest-Neighbor model. Following the event generation procedure, the negative consequences of flooding are analyzed. The corresponding flood damage for each synthetic event is estimated by combining the synthetic discharge at representative points of the river network with a loss probability relation for each community in the study area. The loss probability relation is based on exposure and susceptibility analyses on a single object basis (residential buildings) for certain return periods. For these impact analyses official inundation maps of the study area are used. Finally, by analyzing the total event time series of damages, the expected annual damage or losses associated with a certain probability of occurrence can be estimated for the entire study area.

  6. A 500-kiloton airburst over Chelyabinsk and an enhanced hazard from small impactors

    NASA Astrophysics Data System (ADS)

    Brown, P. G.; Assink, J. D.; Astiz, L.; Blaauw, R.; Boslough, M. B.; Borovička, J.; Brachet, N.; Brown, D.; Campbell-Brown, M.; Ceranna, L.; Cooke, W.; de Groot-Hedlin, C.; Drob, D. P.; Edwards, W.; Evers, L. G.; Garces, M.; Gill, J.; Hedlin, M.; Kingery, A.; Laske, G.; Le Pichon, A.; Mialle, P.; Moser, D. E.; Saffer, A.; Silber, E.; Smets, P.; Spalding, R. E.; Spurný, P.; Tagliaferri, E.; Uren, D.; Weryk, R. J.; Whitaker, R.; Krzeminski, Z.

    2013-11-01

    Most large (over a kilometre in diameter) near-Earth asteroids are now known, but recognition that airbursts (or fireballs resulting from nuclear-weapon-sized detonations of meteoroids in the atmosphere) have the potential to do greater damage than previously thought has shifted an increasing portion of the residual impact risk (the risk of impact from an unknown object) to smaller objects. Above the threshold size of impactor at which the atmosphere absorbs sufficient energy to prevent a ground impact, most of the damage is thought to be caused by the airburst shock wave, but owing to lack of observations this is uncertain. Here we report an analysis of the damage from the airburst of an asteroid about 19 metres (17 to 20 metres) in diameter southeast of Chelyabinsk, Russia, on 15 February 2013, estimated to have an energy equivalent of approximately 500 (+/-100) kilotons of trinitrotoluene (TNT, where 1 kiloton of TNT = 4.185×1012 joules). We show that a widely referenced technique of estimating airburst damage does not reproduce the observations, and that the mathematical relations based on the effects of nuclear weapons--almost always used with this technique--overestimate blast damage. This suggests that earlier damage estimates near the threshold impactor size are too high. We performed a global survey of airbursts of a kiloton or more (including Chelyabinsk), and find that the number of impactors with diameters of tens of metres may be an order of magnitude higher than estimates based on other techniques. This suggests a non-equilibrium (if the population were in a long-term collisional steady state the size-frequency distribution would either follow a single power law or there must be a size-dependent bias in other surveys) in the near-Earth asteroid population for objects 10 to 50 metres in diameter, and shifts more of the residual impact risk to these sizes.

  7. The modal surface interpolation method for damage localization

    NASA Astrophysics Data System (ADS)

    Pina Limongelli, Maria

    2017-05-01

    The Interpolation Method (IM) has been previously proposed and successfully applied for damage localization in plate like structures. The method is based on the detection of localized reductions of smoothness in the Operational Deformed Shapes (ODSs) of the structure. The IM can be applied to any type of structure provided the ODSs are estimated accurately in the original and in the damaged configurations. If the latter circumstance fails to occur, for example when the structure is subjected to an unknown input(s) or if the structural responses are strongly corrupted by noise, both false and missing alarms occur when the IM is applied to localize a concentrated damage. In order to overcome these drawbacks a modification of the method is herein investigated. An ODS is the deformed shape of a structure subjected to a harmonic excitation: at resonances the ODS are dominated by the relevant mode shapes. The effect of noise at resonance is usually lower with respect to other frequency values hence the relevant ODS are estimated with higher reliability. Several methods have been proposed to reliably estimate modal shapes in case of unknown input. These two circumstances can be exploited to improve the reliability of the IM. In order to reduce or eliminate the drawbacks related to the estimation of the ODSs in case of noisy signals, in this paper is investigated a modified version of the method based on a damage feature calculated considering the interpolation error relevant only to the modal shapes and not to all the operational shapes in the significant frequency range. Herein will be reported the comparison between the results of the IM in its actual version (with the interpolation error calculated summing up the contributions of all the operational shapes) and in the new proposed version (with the estimation of the interpolation error limited to the modal shapes).

  8. Building Damage Assessment after Earthquake Using Post-Event LiDAR Data

    NASA Astrophysics Data System (ADS)

    Rastiveis, H.; Eslamizade, F.; Hosseini-Zirdoo, E.

    2015-12-01

    After an earthquake, damage assessment plays an important role in leading rescue team to help people and decrease the number of mortality. Damage map is a map that demonstrates collapsed buildings with their degree of damage. With this map, finding destructive buildings can be quickly possible. In this paper, we propose an algorithm for automatic damage map generation after an earthquake using post-event LiDAR Data and pre-event vector map. The framework of the proposed approach has four main steps. To find the location of all buildings on LiDAR data, in the first step, LiDAR data and vector map are registered by using a few number of ground control points. Then, building layer, selected from vector map, are mapped on the LiDAR data and all pixels which belong to the buildings are extracted. After that, through a powerful classifier all the extracted pixels are classified into three classes of "debris", "intact building" and "unclassified". Since textural information make better difference between "debris" and "intact building" classes, different textural features are applied during the classification. After that, damage degree for each candidate building is estimated based on the relation between the numbers of pixels labelled as "debris" class to the whole building area. Calculating the damage degree for each candidate building, finally, building damage map is generated. To evaluate the ability proposed method in generating damage map, a data set from Port-au-Prince, Haiti's capital after the 2010 Haiti earthquake was used. In this case, after calculating of all buildings in the test area using the proposed method, the results were compared to the damage degree which estimated through visual interpretation of post-event satellite image. Obtained results were proved the reliability of the proposed method in damage map generation using LiDAR data.

  9. On the Representation of Turbulent Stresses for Computing Blood Damage

    PubMed Central

    Hund, Samuel J.; Antaki, James F.; Massoudi, Mehrdad

    2011-01-01

    Computational prediction of blood damage has become a crucial tool for evaluating blood-wetted medical devices and pathological hemodynamics. A difficulty arises in predicting blood damage under turbulent flow conditions because the total stress is indeterminate. Common practice uses the Reynolds stress as an estimation of the total stress causing damage to the blood cells. This study investigates the error introduced by making this substitution, and further shows that energy dissipation is a more appropriate metric of blood trauma. PMID:21318093

  10. An Investigation of Widespread Ozone Damage to the Soybean Crop in the Upper Midwest Determined From Ground-Based and Satellite Measurements

    NASA Technical Reports Server (NTRS)

    Fishman, Jack; Creilson, John K.; Parker, Peter A.; Ainsworth, Elizabeth A.; Vining, G. Geoffrey; Szarka, John; Booker, Fitzgerald L.; Xu, Xiaojing

    2010-01-01

    Elevated concentrations of ground-level ozone (O3) are frequently measured over farmland regions in many parts of the world. While numerous experimental studies show that O3 can significantly decrease crop productivity, independent verifications of yield losses at current ambient O3 concentrations in rural locations are sparse. In this study, soybean crop yield data during a 5-year period over the Midwest of the United States were combined with ground and satellite O3 measurements to provide evidence that yield losses on the order of 10% could be estimated through the use of a multiple linear regression model. Yield loss trends based on both conventional ground-based instrumentation and satellite-derived tropospheric O3 measurements were statistically significant and were consistent with results obtained from open-top chamber experiments and an open-air experimental facility (SoyFACE, Soybean Free Air Concentration Enrichment) in central Illinois. Our analysis suggests that such losses are a relatively new phenomenon due to the increase in background tropospheric O3 levels over recent decades. Extrapolation of these findings supports previous studies that estimate the global economic loss to the farming community of more than $10 billion annually.

  11. How do we best estimate fluvial flood risk in urban environments? : The case of the city of Eilenburg, Germany

    NASA Astrophysics Data System (ADS)

    Longo, Elisa; Tito Aronica, Giuseppe; Di Baldassarre, Giuliano; Mukolwe, Micah

    2015-04-01

    Flooding is one of the most impactful natural hazards. In particular, by looking at the data of damages from natural hazards in Europe collected in the International Disaster Database (EM-DAT) one can see a significant increase over the past four decades of both frequency of floods and associated economic damages. Similarly, dramatic trends are also found by analyzing other types of flood losses, such as the number of people affected by floods, homeless, injured or killed. To deal with the aforementioned increase of flood risk, more and more efforts are being made to promote integrated flood risk management, for instance, at the end of 2007, the European Community (EC) issued the Flood Directive (F.D.) 2007/60/EC. One of the major innovations was that the F.D. 2007/60/C requires Member State to carry out risk maps and then take appropriate measures to reduce the evaluated risk. The main goal of this research was to estimate flood damaging using a computer code based on a recently developed method (KULTURisk, www.kulturisk.eu) and to compare the estimated damage with the observed one. The study area was the municipality of Eilenburg, which in 2002 was subjected to a destructive flood event. Were produced flood damage maps with new procedures (e.g. KULTURisk) and compared the estimates with observed data. This study showed the possibility to extend the lesson learned with the Eilenburg case study in other similar contexts. The outcomes of this test provided interesting insights about the flood risk mapping, which are expected to contribute to raise awareness to the flooding issues,to plan (structural and/or non-structural) measures of flood risk reduction and to support better land-use and urban planning.

  12. Earthquake risk assessment of Alexandria, Egypt

    NASA Astrophysics Data System (ADS)

    Badawy, Ahmed; Gaber, Hanan; Ibrahim, Hamza

    2015-01-01

    Throughout historical and recent times, Alexandria has suffered great damage due to earthquakes from both near- and far-field sources. Sometimes, the sources of such damages are not well known. During the twentieth century, the city was shaken by several earthquakes generated from inland dislocations (e.g., 29 Apr. 1974, 12 Oct. 1992, and 28 Dec. 1999) and the African continental margin (e.g., 12 Sept. 1955 and 28 May 1998). Therefore, this study estimates the earthquake ground shaking and the consequent impacts in Alexandria on the basis of two earthquake scenarios. The simulation results show that Alexandria affected by both earthquakes scenarios relatively in the same manner despite the number of casualties during the first scenario (inland dislocation) is twice larger than the second one (African continental margin). An expected percentage of 2.27 from Alexandria's total constructions (12.9 millions, 2006 Census) will be affected, 0.19 % injuries and 0.01 % deaths of the total population (4.1 millions, 2006 Census) estimated by running the first scenario. The earthquake risk profile reveals that three districts (Al-Montazah, Al-Amriya, and Shark) lie in high seismic risks, two districts (Gharb and Wasat) are in moderate, and two districts (Al-Gomrok and Burg El-Arab) are in low seismic risk level. Moreover, the building damage estimations reflect that Al-Montazah is the highest vulnerable district whereas 73 % of expected damages were reported there. The undertaken analysis shows that the Alexandria urban area faces high risk. Informal areas and deteriorating buildings and infrastructure make the city particularly vulnerable to earthquake risks. For instance, more than 90 % of the estimated earthquake risks (buildings damages) are concentrated at the most densely populated (Al-Montazah, Al-Amriya, and Shark) districts. Moreover, about 75 % of casualties are in the same districts.

  13. Empirical Fragility Analysis of Buildings and Boats Damaged By the 2011 Great East Japan Tsunami and Their Practical Application

    NASA Astrophysics Data System (ADS)

    Suppasri, A.; Charvet, I.; Leelawat, N.; Fukutani, Y.; Muhari, A.; Futami, T.; Imamura, F.

    2014-12-01

    This study focused in turn on detailed data of buildings and boats damage caused by the 2011 tsunami in order to understand its main causes and provide damage probability estimates. Tsunami-induced building damage data was collected from field surveys, and includes inundation depth, building material, number of stories and occupancy type for more than 80,000 buildings. Numerical simulations with high resolution bathymetry and topography data were conducted to obtain characteristic tsunami measures such as flow velocity. These data were analyzed using advanced statistical methods, ordinal regression analysis to create not only empirical 2D tsunami fragility curves, but also 3D tsunami fragility surfaces for the first time. The effect of floating debris was also considered, by using a binary indicator of debris impact based on the proximity of a structure from a debris source (i.e. washed away building). Both the 2D and 3D fragility analyses provided results for each different building damage level, and different topography. While 2D fragility curves provide easily interpretable results relating tsunami flow depth to damage probability for different damage levels, 3D fragility surfaces allow for several influential tsunami parameters to be taken into account thus reduce uncertainty in the probability estimations. More than 20,000 damaged boats were used in the analysis similar to the one carried out on the buildings. Detailed data for each boat comprises information on the damage ratio (paid value over insured value), tonnage, engine type, material type and damage classification. The 2D and 3D fragility analyses were developed using representative tsunami heights for each port obtained from field surveys and flow velocities obtained from the aforementioned simulations. The results are currently being adapted for practical disaster mitigation. They are being integrated with the probabilistic tsunami hazard analysis, in order to create offshore and onshore probabilistic hazard maps. Through the GPS and embedded calculation function based on the aforementioned fragility results, these applications can be used in the field for a quick estimation of possible building damage, as well as a decision support system for fishermen (whether or not they should move their boats to the deep sea upon tsunami arrival).

  14. The magnitude of impact damage on LDEF materials

    NASA Technical Reports Server (NTRS)

    Allbrooks, Martha; Atkinson, Dale

    1992-01-01

    The purpose of this report is to document the magnitude and types of impact damage to materials and systems on the LDEF. This report will provide insights which permit NASA and industry space-systems designers to more rapidly identify potential problems and hazards in placing a spacecraft in low-Earth orbit (LEO). This report is structured to provide (1) a background on LDEF, (2) an introduction to the LEO meteoroid and debris environments, and (3) descriptions of the types of damage caused by impacts into structural materials, and contamination caused by spallation and ejecta from impact events.

  15. Microarray image analysis: background estimation using quantile and morphological filters.

    PubMed

    Bengtsson, Anders; Bengtsson, Henrik

    2006-02-28

    In a microarray experiment the difference in expression between genes on the same slide is up to 103 fold or more. At low expression, even a small error in the estimate will have great influence on the final test and reference ratios. In addition to the true spot intensity the scanned signal consists of different kinds of noise referred to as background. In order to assess the true spot intensity background must be subtracted. The standard approach to estimate background intensities is to assume they are equal to the intensity levels between spots. In the literature, morphological opening is suggested to be one of the best methods for estimating background this way. This paper examines fundamental properties of rank and quantile filters, which include morphological filters at the extremes, with focus on their ability to estimate between-spot intensity levels. The bias and variance of these filter estimates are driven by the number of background pixels used and their distributions. A new rank-filter algorithm is implemented and compared to methods available in Spot by CSIRO and GenePix Pro by Axon Instruments. Spot's morphological opening has a mean bias between -47 and -248 compared to a bias between 2 and -2 for the rank filter and the variability of the morphological opening estimate is 3 times higher than for the rank filter. The mean bias of Spot's second method, morph.close.open, is between -5 and -16 and the variability is approximately the same as for morphological opening. The variability of GenePix Pro's region-based estimate is more than ten times higher than the variability of the rank-filter estimate and with slightly more bias. The large variability is because the size of the background window changes with spot size. To overcome this, a non-adaptive region-based method is implemented. Its bias and variability are comparable to that of the rank filter. The performance of more advanced rank filters is equal to the best region-based methods. However, in order to get unbiased estimates these filters have to be implemented with great care. The performance of morphological opening is in general poor with a substantial spatial-dependent bias.

  16. Background estimation and player detection in badminton video clips using histogram of pixel values along temporal dimension

    NASA Astrophysics Data System (ADS)

    Peng, Yahui; Ma, Xiao; Gao, Xinyu; Zhou, Fangxu

    2015-12-01

    Computer vision is an important tool for sports video processing. However, its application in badminton match analysis is very limited. In this study, we proposed a straightforward but robust histogram-based background estimation and player detection methods for badminton video clips, and compared the results with the naive averaging method and the mixture of Gaussians methods, respectively. The proposed method yielded better background estimation results than the naive averaging method and more accurate player detection results than the mixture of Gaussians player detection method. The preliminary results indicated that the proposed histogram-based method could estimate the background and extract the players accurately. We conclude that the proposed method can be used for badminton player tracking and further studies are warranted for automated match analysis.

  17. Economics of social trade-off: Balancing wastewater treatment cost and ecosystem damage.

    PubMed

    Jiang, Yu; Dinar, Ariel; Hellegers, Petra

    2018-04-01

    We have developed a social optimization model that integrates the financial and ecological costs associated with wastewater treatment and ecosystem damage. The social optimal abatement level of water pollution is determined by finding the trade-off between the cost of pollution control and its resulting ecosystem damage. The model is applied to data from the Lake Taihu region in China to demonstrate this trade-off. A wastewater treatment cost function is estimated with a sizable sample from China, and an ecological damage cost function is estimated following an ecosystem service valuation framework. Results show that the wastewater treatment cost function has economies of scale in facility capacity, and diseconomies in pollutant removal efficiency. Results also show that a low value of the ecosystem service will lead to serious ecological damage. One important policy implication is that the assimilative capacity of the lake should be enhanced by forbidding over extraction of water from the lake. It is also suggested that more work should be done to improve the accuracy of the economic valuation. Copyright © 2018 Elsevier Ltd. All rights reserved.

  18. Air Emissions Damages from Municipal Drinking Water Treatment Under Current and Proposed Regulatory Standards.

    PubMed

    Gingerich, Daniel B; Mauter, Meagan S

    2017-09-19

    Water treatment processes present intersectoral and cross-media risk trade-offs that are not presently considered in Safe Drinking Water Act regulatory analyses. This paper develops a method for assessing the air emission implications of common municipal water treatment processes used to comply with recently promulgated and proposed regulatory standards, including concentration limits for, lead and copper, disinfection byproducts, chromium(VI), strontium, and PFOA/PFOS. Life-cycle models of electricity and chemical consumption for individual drinking water unit processes are used to estimate embedded NO x , SO 2 , PM 2.5 , and CO 2 emissions on a cubic meter basis. We estimate air emission damages from currently installed treatment processes at U.S. drinking water facilities to be on the order of $500 million USD annually. Fully complying with six promulgated and proposed rules would increase baseline air emission damages by approximately 50%, with three-quarters of these damages originating from chemical manufacturing. Despite the magnitude of these air emission damages, the net benefit of currently implemented rules remains positive. For some proposed rules, however, the promise of net benefits remains contingent on technology choice.

  19. Nonlinear finite element model updating for damage identification of civil structures using batch Bayesian estimation

    NASA Astrophysics Data System (ADS)

    Ebrahimian, Hamed; Astroza, Rodrigo; Conte, Joel P.; de Callafon, Raymond A.

    2017-02-01

    This paper presents a framework for structural health monitoring (SHM) and damage identification of civil structures. This framework integrates advanced mechanics-based nonlinear finite element (FE) modeling and analysis techniques with a batch Bayesian estimation approach to estimate time-invariant model parameters used in the FE model of the structure of interest. The framework uses input excitation and dynamic response of the structure and updates a nonlinear FE model of the structure to minimize the discrepancies between predicted and measured response time histories. The updated FE model can then be interrogated to detect, localize, classify, and quantify the state of damage and predict the remaining useful life of the structure. As opposed to recursive estimation methods, in the batch Bayesian estimation approach, the entire time history of the input excitation and output response of the structure are used as a batch of data to estimate the FE model parameters through a number of iterations. In the case of non-informative prior, the batch Bayesian method leads to an extended maximum likelihood (ML) estimation method to estimate jointly time-invariant model parameters and the measurement noise amplitude. The extended ML estimation problem is solved efficiently using a gradient-based interior-point optimization algorithm. Gradient-based optimization algorithms require the FE response sensitivities with respect to the model parameters to be identified. The FE response sensitivities are computed accurately and efficiently using the direct differentiation method (DDM). The estimation uncertainties are evaluated based on the Cramer-Rao lower bound (CRLB) theorem by computing the exact Fisher Information matrix using the FE response sensitivities with respect to the model parameters. The accuracy of the proposed uncertainty quantification approach is verified using a sampling approach based on the unscented transformation. Two validation studies, based on realistic structural FE models of a bridge pier and a moment resisting steel frame, are performed to validate the performance and accuracy of the presented nonlinear FE model updating approach and demonstrate its application to SHM. These validation studies show the excellent performance of the proposed framework for SHM and damage identification even in the presence of high measurement noise and/or way-out initial estimates of the model parameters. Furthermore, the detrimental effects of the input measurement noise on the performance of the proposed framework are illustrated and quantified through one of the validation studies.

  20. A Methodology for Forecasting Damage & Economic Consequences to Floods: Building on the National Flood Interoperability Experiment (NFIE)

    NASA Astrophysics Data System (ADS)

    Tootle, G. A.; Gutenson, J. L.; Zhu, L.; Ernest, A. N. S.; Oubeidillah, A.; Zhang, X.

    2015-12-01

    The National Flood Interoperability Experiment (NFIE) held June 3-July 17, 2015 at the National Water Center (NWC) in Tuscaloosa, Alabama sought to demonstrate an increase in flood predictive capacity for the coterminous United States (CONUS). Accordingly, NFIE-derived technologies and workflows offer the ability to forecast flood damage and economic consequence estimates that coincide with the hydrologic and hydraulic estimations these physics-based models generate. A model providing an accurate prediction of damage and economic consequences is a valuable asset when allocating funding for disaster response, recovery, and relief. Damage prediction and economic consequence assessment also offer an adaptation planning mechanism for defending particularly valuable or vulnerable structures. The NFIE, held at the NWC on The University of Alabama (UA) campus led to the development of this large scale flow and inundation forecasting framework. Currently, the system can produce 15-hour lead-time forecasts for the entire coterminous United States (CONUS). A concept which is anticipated to become operational as of May 2016 within the NWC. The processing of such a large-scale, fine resolution model is accomplished in a parallel computing environment using large supercomputing clusters. Traditionally, flood damage and economic consequence assessment is calculated in a desktop computing environment with a ménage of meteorology, hydrology, hydraulic, and damage assessment tools. In the United States, there are a range of these flood damage/ economic consequence assessment software's available to local, state, and federal emergency management agencies. Among the more commonly used and freely accessible models are the Hydrologic Engineering Center's Flood Damage Reduction Analysis (HEC-FDA), Flood Impact Assessment (HEC-FIA), and Federal Emergency Management Agency's (FEMA's) United States Multi-Hazard (Hazus-MH). All of which exist only in a desktop environment. With this, authors submit an initial framework for estimating damage and economic consequences to floods using flow and inundation products from the NFIE framework. This adaptive system utilizes existing nationwide datasets describing location and use of structures and can take assimilate a range of data resolutions.

  1. Prediction and mitigation of scour and scour damage to Vermont bridges.

    DOT National Transportation Integrated Search

    2017-02-20

    Over 300 Vermont bridges were damaged in the 2011 Tropical Storm Irene and many experienced significant scour. Successfully mitigating bridge scour in future flooding events depends on our ability to reliably estimate scour potential, design safe and...

  2. Scaling future tropical cyclone damage with global mean temperature

    NASA Astrophysics Data System (ADS)

    Geiger, T.; Bresch, D.; Frieler, K.

    2017-12-01

    Tropical cyclones (TC) are one of the most damaging natural hazards and severely affectmany countries around the globe each year. Their nominal impact is projected to increasesubstantially as the exposed coastal population grows, per capita income increases, andanthropogenic climate change manifests. The magnitude of this increase, however, variesacross regions and is obscured by the stochastic behaviour of TCs, so far impeding arigorous quantification of trends in TC damage with global mean temperature (GMT) rise. Here, we build on the large sample of spatially explicit TCs simulations generated withinISIMIP(2b) for 1) pre-industrial conditions, 2) the historical period, and 3) future projectionsunder RCP2.6 and RCP6.0 to estimate future TC damage assuming fixed present-daysocio-economic conditions or SSP-based future projections of population patterns andincome. Damage estimates will be based on region-specific empirical damage modelsderived from reported damages and accounting for regional characteristics of vulnerability.Different combinations of 1) socio-economic drivers with pre-industrial climate or 2) changingclimate with fixed socio-economic conditions will be used to derive functional relationshipsbetween regionally aggregated changes in damages on one hand and global meantemperature and socio-economic predictors on the other hand. The obtained region-specific scaling of future TC damage with GMT provides valuable inputfor IPCC's special report on the impacts of global warming of 1.5°C by quantifying theincremental changes in impact with global warming. The approach allows for an update ofdamage functions used in integrated assessment models, and contributes to assessing theadequateness of climate mitigation and adaptation strategies.

  3. Genotoxic Effects of Low- and High-LET Radiation on Human Epithelial Cells Grown in 2-D Versus 3-D Culture

    NASA Technical Reports Server (NTRS)

    Patel, Z. S.; Cucinotta, F. A.; Huff, J. L.

    2011-01-01

    Risk estimation for radiation-induced cancer relies heavily on human epidemiology data obtained from terrestrial irradiation incidents from sources such as medical and occupational exposures as well as from the atomic bomb survivors. No such data exists for exposures to the types and doses of high-LET radiation that will be encountered during space travel; therefore, risk assessment for space radiation requires the use of data derived from cell culture and animal models. The use of experimental models that most accurately replicate the response of human tissues is critical for precision in risk projections. This work compares the genotoxic effects of radiation on normal human epithelial cells grown in standard 2-D monolayer culture compared to 3-D organotypic co-culture conditions. These 3-D organotypic models mimic the morphological features, differentiation markers, and growth characteristics of fully-differentiated normal human tissue and are reproducible using defined components. Cultures were irradiated with 2 Gy low-LET gamma rays or varying doses of high-LET particle radiation and genotoxic damage was measured using a modified cytokinesis block micronucleus assay. Our results revealed a 2-fold increase in residual damage in 2 Gy gamma irradiated cells grown under organotypic culture conditions compared to monolayer culture. Irradiation with high-LET particle radiation gave similar results, while background levels of damage were comparable under both scenarios. These observations may be related to the phenomenon of "multicellular resistance" where cancer cells grown as 3-D spheroids or in vivo exhibit an increased resistance to killing by chemotherapeutic agents compared to the same cells grown in 2-D culture. A variety of factors are likely involved in mediating this process, including increased cell-cell communication, microenvironment influences, and changes in cell cycle kinetics that may promote survival of damaged cells in 3-D culture that would otherwise die or be rendered reproductively inactive in 2-D culture.

  4. Assessing the Social and Environmental Costs of Institution Nitrogen Footprints

    PubMed Central

    Leach, Allison M.; Castner, Elizabeth A.; Galloway, James N.

    2017-01-01

    Abstract This article estimates the damage costs associated with the institutional nitrogen (N) footprint and explores how this information could be used to create more sustainable institutions. Potential damages associated with the release of nitrogen oxides (NOx), ammonia (NH3), and nitrous oxide (N2O) to air and release of nitrogen to water were estimated using existing values and a cost per unit of nitrogen approach. These damage cost values were then applied to two universities. Annual potential damage costs to human health, agriculture, and natural ecosystems associated with the N footprint of institutions were $11.0 million (2014) at the University of Virginia (UVA) and $3.04 million at the University of New Hampshire (UNH). Costs associated with the release of nitrogen oxides to human health, in particular the use of coal-derived energy, were the largest component of damage at UVA. At UNH the energy N footprint is much lower because of a landfill cogeneration source, and thus the majority of damages were associated with food production. Annual damages associated with release of nitrogen from food production were very similar at the two universities ($1.80 million vs. $1.66 million at UVA and UNH, respectively). These damages also have implications for the extent and scale at which the damages are felt. For example, impacts to human health from energy and transportation are generally larger near the power plants and roads, while impacts from food production can be distant from the campus. Making this information available to institutions and communities can improve their understanding of the damages associated with the different nitrogen forms and sources, and inform decisions about nitrogen reduction strategies. PMID:29350221

  5. Assessing the Social and Environmental Costs of Institution Nitrogen Footprints.

    PubMed

    Compton, Jana E; Leach, Allison M; Castner, Elizabeth A; Galloway, James N

    2017-04-01

    This article estimates the damage costs associated with the institutional nitrogen (N) footprint and explores how this information could be used to create more sustainable institutions. Potential damages associated with the release of nitrogen oxides (NOx), ammonia (NH 3 ), and nitrous oxide (N 2 O) to air and release of nitrogen to water were estimated using existing values and a cost per unit of nitrogen approach. These damage cost values were then applied to two universities. Annual potential damage costs to human health, agriculture, and natural ecosystems associated with the N footprint of institutions were $11.0 million (2014) at the University of Virginia (UVA) and $3.04 million at the University of New Hampshire (UNH). Costs associated with the release of nitrogen oxides to human health, in particular the use of coal-derived energy, were the largest component of damage at UVA. At UNH the energy N footprint is much lower because of a landfill cogeneration source, and thus the majority of damages were associated with food production. Annual damages associated with release of nitrogen from food production were very similar at the two universities ($1.80 million vs. $1.66 million at UVA and UNH, respectively). These damages also have implications for the extent and scale at which the damages are felt. For example, impacts to human health from energy and transportation are generally larger near the power plants and roads, while impacts from food production can be distant from the campus. Making this information available to institutions and communities can improve their understanding of the damages associated with the different nitrogen forms and sources, and inform decisions about nitrogen reduction strategies.

  6. Are Tornadoes Getting Stronger?

    NASA Astrophysics Data System (ADS)

    Elsner, J.; Jagger, T.

    2013-12-01

    A cumulative logistic model for tornado damage category is developed and examined. Damage path length and width are significantly correlated to the odds of a tornado receiving the next highest damage category. Given values for the cube root of path length and square root of path width, the model predicts a probability for each category. The length and width coefficients are insensitive to the switch to the Enhanced Fujita (EF) scale and to distance from nearest city although these variables are statistically significant in the model. The width coefficient is sensitive to whether or not the tornado caused at least one fatality. This is likely due to the fact that the dimensions and characteristics of the damage path for such events are always based on ground surveys. The model predicted probabilities across the categories are then multiplied by the center wind speed from the categorical EF scale to obtain an estimate of the highest tornado wind speed on a continuous scale in units of meters per second. The estimated wind speeds correlate at a level of .82 (.46, .95) [95% confidence interval] to wind speeds estimated independently from a doppler radar calibration. The estimated wind speeds allow analyses to be done on the tornado database that are not possible with the categorical scale. The modeled intensities can be used in climatology and in environmental and engineering applications. More work needs to be done to understand the upward trends in path length and width. The increases lead to an apparent increase in tornado intensity across all EF categories.

  7. Durability and Damage Tolerance of High Temperature Polymeric Composites

    NASA Technical Reports Server (NTRS)

    Case, Scott W.; Reifsnider, Kenneth L.

    1996-01-01

    Modern durability and damage tolerance predictions for composite material systems rely on accurate estimates of the local stress and material states for each of the constituents, as well as the manner in which the constituents interact. In this work, an number of approaches to estimating the stress states and interactions are developed. First, an elasticity solution is presented for the problem of a penny-shaped crack in an N-phase composite material system opened by a prescribed normal pressure. The stress state around such a crack is then used to estimate the stress concentrations due to adjacent fiber fractures in composite materials. The resulting stress concentrations are then used to estimate the tensile strength of the composite. The predicted results are compared with experimental values. In addition, a cumulative damage model for fatigue is presented. Modifications to the model are made to include the effects of variable amplitude loading. These modifications are based upon the use of remaining strength as a damage metric and the definition of an equivalent generalized time. The model is initially validated using results from the literature. Also, experimental data from APC-2 laminates and IM7/K3B laminates are used in the model. The use of such data for notched laminates requires the use of an effective hole size, which is calculated based upon strain distribution measurements. Measured remaining strengths after fatigue loading are compared with the predicted values for specimens fatigued at room temperature and 350 F (177 C).

  8. The social costs of nitrogen

    PubMed Central

    Keeler, Bonnie L.; Gourevitch, Jesse D.; Polasky, Stephen; Isbell, Forest; Tessum, Chris W.; Hill, Jason D.; Marshall, Julian D.

    2016-01-01

    Despite growing recognition of the negative externalities associated with reactive nitrogen (N), the damage costs of N to air, water, and climate remain largely unquantified. We propose a comprehensive approach for estimating the social cost of nitrogen (SCN), defined as the present value of the monetary damages caused by an incremental increase in N. This framework advances N accounting by considering how each form of N causes damages at specific locations as it cascades through the environment. We apply the approach to an empirical example that estimates the SCN for N applied as fertilizer. We track impacts of N through its transformation into atmospheric and aquatic pools and estimate the distribution of associated costs to affected populations. Our results confirm that there is no uniform SCN. Instead, changes in N management will result in different N-related costs depending on where N moves and the location, vulnerability, and preferences of populations affected by N. For example, we found that the SCN per kilogram of N fertilizer applied in Minnesota ranges over several orders of magnitude, from less than $0.001/kg N to greater than $10/kg N, illustrating the importance of considering the site, the form of N, and end points of interest rather than assuming a uniform cost for damages. Our approach for estimating the SCN demonstrates the potential of integrated biophysical and economic models to illuminate the costs and benefits of N and inform more strategic and efficient N management. PMID:27713926

  9. Current concepts in the management of hidradenitis suppurativa in children.

    PubMed

    Danby, F William

    2015-08-01

    This review is intended to provide the background aetiopathogenetic framework upon which management of this disorder can be based, particularly with relation to new concepts of the pathogenesis of the disorder. The emphasis is on the prevention of the disorder's full expression by addressing the metabolic changes that drive the underlying structural damage and the immune system's subsequent reaction to this damage. The mechanism by which dietary factors impact on this disease are elucidated, the anatomic defect suspected to be responsible for the disorder is introduced, and an updated flow sheet describing and linking the clinicopathological changes recently described are provided. Recent work in the understanding of the induction and evolution of the lesions provides a background upon which the preventive regimen and both the medical and surgical approaches can be effectively based.

  10. Estimating the residual axial load capacity of flexure-dominated reinforced concrete bridge columns.

    DOT National Transportation Integrated Search

    2014-08-01

    Extreme events such as earthquakes have the potential to damage hundreds, if not thousands, of bridges on a : transportation network. Following an earthquake, the damaged bridges are inspected by engineers sequentially to : decide whether or not to c...

  11. Characterization of background concentrations of contaminants using a mixture of normal distributions.

    PubMed

    Qian, Song S; Lyons, Regan E

    2006-10-01

    We present a Bayesian approach for characterizing background contaminant concentration distributions using data from sites that may have been contaminated. Our method, focused on estimation, resolves several technical problems of the existing methods sanctioned by the U.S. Environmental Protection Agency (USEPA) (a hypothesis testing based method), resulting in a simple and quick procedure for estimating background contaminant concentrations. The proposed Bayesian method is applied to two data sets from a federal facility regulated under the Resource Conservation and Restoration Act. The results are compared to background distributions identified using existing methods recommended by the USEPA. The two data sets represent low and moderate levels of censorship in the data. Although an unbiased estimator is elusive, we show that the proposed Bayesian estimation method will have a smaller bias than the EPA recommended method.

  12. Economic damages of ozone air pollution to crops using combined air quality and GIS modelling

    NASA Astrophysics Data System (ADS)

    Vlachokostas, Ch.; Nastis, S. A.; Achillas, Ch.; Kalogeropoulos, K.; Karmiris, I.; Moussiopoulos, N.; Chourdakis, E.; Banias, G.; Limperi, N.

    2010-09-01

    This study aims at presenting a combined air quality and GIS modelling methodological approach in order to estimate crop damages from photochemical air pollution, depict their spatial resolution and assess the order of magnitude regarding the corresponding economic damages. The analysis is conducted within the Greater Thessaloniki Area, Greece, a Mediterranean territory which is characterised by high levels of photochemical air pollution and considerable agricultural activity. Ozone concentration fields for 2002 and for specific emission reduction scenarios for the year 2010 were estimated with the Ozone Fine Structure model in the area under consideration. Total economic damage to crops turns out to be significant and estimated to be approximately 43 M€ for the reference year. Production of cotton presents the highest economic loss, which is over 16 M€, followed by table tomato (9 M€), rice (4.2 M€), wheat (4 M€) and oilseed rape (2.8 M€) cultivations. Losses are not spread uniformly among farmers and the major losses occur in areas with valuable ozone-sensitive crops. The results are very useful for highlighting the magnitude of the total economic impacts of photochemical air pollution to the area's agricultural sector and can potentially be used for comparison with studies worldwide. Furthermore, spatial analysis of the economic damage could be of importance for governmental authorities and decision makers since it provides an indicative insight, especially if the economic instruments such as financial incentives or state subsidies to farmers are considered.

  13. Overview of the Special Issue: A Multi-Model Framework to Achieve Consistent Evaluation of Climate Change Impacts in the United States

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Waldhoff, Stephanie T.; Martinich, Jeremy; Sarofim, Marcus

    2015-07-01

    The Climate Change Impacts and Risk Analysis (CIRA) modeling exercise is a unique contribution to the scientific literature on climate change impacts, economic damages, and risk analysis that brings together multiple, national-scale models of impacts and damages in an integrated and consistent fashion to estimate climate change impacts, damages, and the benefits of greenhouse gas (GHG) mitigation actions in the United States. The CIRA project uses three consistent socioeconomic, emissions, and climate scenarios across all models to estimate the benefits of GHG mitigation policies: a Business As Usual (BAU) and two policy scenarios with radiative forcing (RF) stabilization targets ofmore » 4.5 W/m2 and 3.7 W/m2 in 2100. CIRA was also designed to specifically examine the sensitivity of results to uncertainties around climate sensitivity and differences in model structure. The goals of CIRA project are to 1) build a multi-model framework to produce estimates of multiple risks and impacts in the U.S., 2) determine to what degree risks and damages across sectors may be lowered from a BAU to policy scenarios, 3) evaluate key sources of uncertainty along the causal chain, and 4) provide information for multiple audiences and clearly communicate the risks and damages of climate change and the potential benefits of mitigation. This paper describes the motivations, goals, and design of the CIRA modeling exercise and introduces the subsequent papers in this special issue.« less

  14. Estimating North American background ozone in U.S. surface air with two independent global models: Variability, uncertainties, and recommendations

    EPA Science Inventory

    Accurate estimates for North American background (NAB) ozone (O3) in surface air over the United States are needed for setting and implementing an attainable national O3 standard. These estimates rely on simulations with atmospheric chemistry-transport models that set North Amer...

  15. Estimation of flood environmental effects using flood zone mapping techniques in Halilrood Kerman, Iran.

    PubMed

    Boudaghpour, Siamak; Bagheri, Majid; Bagheri, Zahra

    2014-01-01

    High flood occurrences with large environmental damages have a growing trend in Iran. Dynamic movements of water during a flood cause different environmental damages in geographical areas with different characteristics such as topographic conditions. In general, environmental effects and damages caused by a flood in an area can be investigated from different points of view. The current essay is aiming at detecting environmental effects of flood occurrences in Halilrood catchment area of Kerman province in Iran using flood zone mapping techniques. The intended flood zone map was introduced in four steps. Steps 1 to 3 pave the way to calculate and estimate flood zone map in the understudy area while step 4 determines the estimation of environmental effects of flood occurrence. Based on our studies, wide range of accuracy for estimating the environmental effects of flood occurrence was introduced by using of flood zone mapping techniques. Moreover, it was identified that the existence of Jiroft dam in the study area can decrease flood zone from 260 hectares to 225 hectares and also it can decrease 20% of flood peak intensity. As a result, 14% of flood zone in the study area can be saved environmentally.

  16. The Benefits of Air and Water Pollution Control: A Review and Synthesis of Recent Estimates (1979)

    EPA Pesticide Factsheets

    Report provides a survey and critical review of the existing literature (by late 1970s) giving estimates of national benefits or damages, adopting a common framework to provide consistent estimates of air and water pollution benefits.

  17. Urban seismic risk assessment: statistical repair cost data and probable structural losses based on damage scenario—correlation analysis

    NASA Astrophysics Data System (ADS)

    Eleftheriadou, Anastasia K.; Baltzopoulou, Aikaterini D.; Karabinis, Athanasios I.

    2016-06-01

    The current seismic risk assessment is based on two discrete approaches, actual and probable, validating afterwards the produced results. In the first part of this research, the seismic risk is evaluated from the available data regarding the mean statistical repair/strengthening or replacement cost for the total number of damaged structures (180,427 buildings) after the 7/9/1999 Parnitha (Athens) earthquake. The actual evaluated seismic risk is afterwards compared to the estimated probable structural losses, which is presented in the second part of the paper, based on a damage scenario in the referring earthquake. The applied damage scenario is based on recently developed damage probability matrices (DPMs) from Athens (Greece) damage database. The seismic risk estimation refers to 750,085 buildings situated in the extended urban region of Athens. The building exposure is categorized in five typical structural types and represents 18.80 % of the entire building stock in Greece. The last information is provided by the National Statistics Service of Greece (NSSG) according to the 2000-2001 census. The seismic input is characterized by the ratio, a g/ a o, where a g is the regional peak ground acceleration (PGA) which is evaluated from the earlier estimated research macroseismic intensities, and a o is the PGA according to the hazard map of the 2003 Greek Seismic Code. Finally, the collected investigated financial data derived from different National Services responsible for the post-earthquake crisis management concerning the repair/strengthening or replacement costs or other categories of costs for the rehabilitation of earthquake victims (construction and function of settlements for earthquake homeless, rent supports, demolitions, shorings) are used to determine the final total seismic risk factor.

  18. Statistical analysis of the uncertainty related to flood hazard appraisal

    NASA Astrophysics Data System (ADS)

    Notaro, Vincenza; Freni, Gabriele

    2015-12-01

    The estimation of flood hazard frequency statistics for an urban catchment is of great interest in practice. It provides the evaluation of potential flood risk and related damage and supports decision making for flood risk management. Flood risk is usually defined as function of the probability, that a system deficiency can cause flooding (hazard), and the expected damage, due to the flooding magnitude (damage), taking into account both the exposure and the vulnerability of the goods at risk. The expected flood damage can be evaluated by an a priori estimation of potential damage caused by flooding or by interpolating real damage data. With regard to flood hazard appraisal several procedures propose to identify some hazard indicator (HI) such as flood depth or the combination of flood depth and velocity and to assess the flood hazard corresponding to the analyzed area comparing the HI variables with user-defined threshold values or curves (penalty curves or matrixes). However, flooding data are usually unavailable or piecemeal allowing for carrying out a reliable flood hazard analysis, therefore hazard analysis is often performed by means of mathematical simulations aimed at evaluating water levels and flow velocities over catchment surface. As results a great part of the uncertainties intrinsic to flood risk appraisal can be related to the hazard evaluation due to the uncertainty inherent to modeling results and to the subjectivity of the user defined hazard thresholds applied to link flood depth to a hazard level. In the present work, a statistical methodology was proposed for evaluating and reducing the uncertainties connected with hazard level estimation. The methodology has been applied to a real urban watershed as case study.

  19. September 2013 Storm and Flood Assessment Report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Walterscheid, J. C.

    2015-12-21

    Between September 10 and 17, 2013, New Mexico and Colorado received a historically large amount of precipitation (Figure 1). This report assesses the damage caused by flooding along with estimated costs to repair the damage at Los Alamos National Laboratory (the Laboratory) on the Pajarito Plateau. Los Alamos County, New Mexico, received between 200% and 600% of the normal precipitation for this time period (Figure 2), and the Laboratory received approximately 450% percent of its average precipitation for September (Figure 3). As a result, the Laboratory was inundated with rain, including the extremely large, greater-than-1000-yr return period event that occurredmore » between September 12 and 13 (Table 1). With saturated antecedent soil conditions from the September 10 storm, when the September 12 to September 13 storm hit, the flooding was disastrous to the Laboratory’s environmental infrastructure, including access roads, gage stations, watershed controls, control measures installed under the National Pollutant Discharge Elimination System Permit (hereafter, the Individual Permit), and groundwater monitoring wells (Figures 4 through 21). From September 16 to October 1, 2013, the Laboratory completed field assessments of environmental infrastructure and generated descriptions and estimates of the damage, which are presented in spreadsheets in Attachments 1 to 4 of this report. Section 2 of this report contains damage assessments by watershed, including access roads, gage stations, watershed controls, and control measures installed under the Individual Permit. Section 3 contains damage assessments of monitoring wells by the groundwater monitoring groups as established in the Interim Facility-Wide Groundwater Monitoring Plan for Monitoring Year 2014. Section 4 addresses damage and loss of automated samplers. Section 5 addresses sediment sampling needs, and Section 6 is the summary of estimated recovery costs from the significant rain and flooding during September 2013.« less

  20. Application of the Flood-IMPAT procedure in the Valle d'Aosta Region, Italy

    NASA Astrophysics Data System (ADS)

    Minucci, Guido; Mendoza, Marina Tamara; Molinari, Daniela; Atun, Funda; Menoni, Scira; Ballio, Francesco

    2016-04-01

    Flood Risk Management Plans (FRMPs) established by European "Floods" Directive (Directive 2007/60/EU) to Member States in order to address all aspects of flood risk management, taking into account costs and benefits of proposed mitigation tools must be reviewed by the same law every six years. This is aimed at continuously increasing the effectiveness of risk management, on the bases of the most advanced knowledge of flood risk and most (economically) feasible solutions, also taking into consideration achievements of the previous management cycle. Within this context, the Flood-IMPAT (i.e. Integrated Meso-scale Procedure to Assess Territorial flood risk) procedure has been developed aiming at overcoming limits of risk maps produced by the Po River Basin Authority and adopted for the first version of the Po River FRMP. The procedure allows the estimation of flood risk at the meso-scale and it is characterized by three main peculiarities. First is its feasibility for the entire Italian territory. Second is the possibility to express risk in monetary terms (i.e. expected damage), at least for those categories of damage for which suitable models are available. Finally, independent modules compose the procedure: each module allows the estimation of a certain type of damage (i.e. direct, indirect, intangibles) on a certain sector (e.g. residential, industrial, agriculture, environment, etc.) separately, guaranteeing flexibility in the implementation. This paper shows the application of the Flood-IMPAT procedure and the recent advancements in the procedure, aiming at increasing its reliability and usability. Through a further implementation of the procedure in the Dora Baltea River Basin (North of Italy), it was possible to test the sensitivity of risk estimates supplied by Flood-IMPAT with respect to different damage models and different approaches for the estimation of assets at risk. Risk estimates were also compared with observed damage data in the investigated areas to identify the most suitable damage model/exposure assessment approach to be implemented in the procedure. In the end, the procedure was adapted to be applied at the micro-scale, in such a way to supply risk estimates, which are coherent with those at the meso-scale. This way the procedure can be first implemented in the whole catchment to identify hotspots; the micro-scale approach can be implemented in a second run to investigate in depth (i) the most risk prone areas and (ii) the possible risk mitigation strategies.

  1. Summary of floods in the United States during 1958

    USGS Publications Warehouse

    Hendricks, E.L.

    1964-01-01

    This report describes the most outstanding floods that occurred in the United States during 1958.A series of storms from January 23 to February 16 brought large amounts of precipitation to northern California and produced damaging floods, particularly in the Lower Sacramento Valley where losses totaled about \\$12 million.Major floods, notable because of the large area affected, occurred on many small streams in central and south Texas, following heavy general rains in late February. Extensive flooding occurred along the Gulf Coastal plain on the lower reaches of the major streams from the Brazos River to the Nueces River. Two lives were lost, and property damage exceeded \\$1 million.Damaging floods of April 1-7 followed one of the wettest winters in California history. Swollen streams overflowed their banks throughout the central part of the State, and discharge peaks on many streams exceeded those .of the floods of December 1955. Most severely flooded was the San Francisco Bay area. Total flood damage was estimated at \\$23 million.The storms and floods of April-May in Louisiana and adjacent States outranked all other floods in the United States during 1958 with respect to intensity of rain over a large area, number of streams having maximum discharge of record, rare occurrence of peaks, and great amount (\\$21 million) of resultant damage.Heavy rains on June 8-15 caused one of the greatest summer floods of record in central Indiana. Peak discharges were high and of rare occurrences. Failure of numerous levees along the Wabash River caused great damage. Crop damage alone was estimated at \\$48 million.Intense rains of July 1-2 caused record-breaking floods in southwestern Iowa. Rapid rises and the great magnitude of the floods on small streams resulted in 18 deaths and many injuries. Six towns and cities along the East Nishnabotna River and its tributaries were particularly hard hit; rural damage was also high. Total damage was estimated at \\$15 million.Heavy rains (as much as 40 inches during the last 2 weeks in September) from the middle of September to the middle of October caused destructive floods along the Rio Grande in Texas and Mexico. Many communities were isolated by the flood waters, and damage to crops was great.In addition to the 7 floods mentioned above, 21 others of lesser magnitude are reported in this annual summary.

  2. Using remotely sensed data and elementary analytical techniques in post-katrina mississippi to examine storm damage modeling

    Treesearch

    Curtis A. Collins; David L. Evans; Keith L. Belli; Patrick A. Glass

    2010-01-01

    Hurricane Katrina’s passage through south Mississippi on August 29, 2005, which damaged or destroyed thousands of hectares of forest land, was followed by massive salvage, cleanup, and assessment efforts. An initial assessment by the Mississippi Forestry Commission estimated that over $1 billion in raw wood material was downed by the storm, with county-level damage...

  3. Estimating willingness to pay for protection of eastern black walnut from deer damage

    Treesearch

    Larry D. Godsey; John P. Dwyer

    2008-01-01

    For many landowners willing to plant trees, one of the biggest establishment and maintenance costs is protecting those young trees from deer browse damage. In some cases, the method of protection used can cost two to three times as much as the cost of planting. Deer damage such as nipping off terminal buds and buck rub penetrating the bark and cambial tissue can kill...

  4. Flood damage assessment using computer-assisted analysis of color infrared photography

    USGS Publications Warehouse

    Anderson, William H.

    1978-01-01

    Use of digitized aerial photographs for flood damage assessment in agriculture is new and largely untested. However, under flooding circumstances similar to the 1975 Red River Valley flood, computer-assisted techniques can be extremely useful, especially if detailed crop damage estimates are needed within a relatively short period of time.Airphoto interpretation techniques, manual or computer-assisted, are not intended to replace conventional ground survey and sampling procedures. But their use should be considered a valuable addition to the tools currently available for assessing agricultural flood damage.

  5. Real-time airborne gamma-ray background estimation using NASVD with MLE and radiation transport for calibration

    NASA Astrophysics Data System (ADS)

    Kulisek, J. A.; Schweppe, J. E.; Stave, S. C.; Bernacki, B. E.; Jordan, D. V.; Stewart, T. N.; Seifert, C. E.; Kernan, W. J.

    2015-06-01

    Helicopter-mounted gamma-ray detectors can provide law enforcement officials the means to quickly and accurately detect, identify, and locate radiological threats over a wide geographical area. The ability to accurately distinguish radiological threat-generated gamma-ray signatures from background gamma radiation in real time is essential in order to realize this potential. This problem is non-trivial, especially in urban environments for which the background may change very rapidly during flight. This exacerbates the challenge of estimating background due to the poor counting statistics inherent in real-time airborne gamma-ray spectroscopy measurements. To address this challenge, we have developed a new technique for real-time estimation of background gamma radiation from aerial measurements without the need for human analyst intervention. The method can be calibrated using radiation transport simulations along with data from previous flights over areas for which the isotopic composition need not be known. Over the examined measured and simulated data sets, the method generated accurate background estimates even in the presence of a strong, 60Co source. The potential to track large and abrupt changes in background spectral shape and magnitude was demonstrated. The method can be implemented fairly easily in most modern computing languages and environments.

  6. Accounting for climate and air quality damages in future U.S. electricity generation scenarios.

    PubMed

    Brown, Kristen E; Henze, Daven K; Milford, Jana B

    2013-04-02

    The EPA-MARKAL model of the U.S. electricity sector is used to examine how imposing emissions fees based on estimated health and environmental damages might change electricity generation. Fees are imposed on life-cycle emissions of SO(2), nitrogen oxides (NO(x)), particulate matter, and greenhouse gases (GHG) from 2015 through 2055. Changes in electricity production, fuel type, emissions controls, and emissions produced under various fees are examined. A shift in fuels used for electricity production results from $30/ton CO(2)-equivalent GHG fees or from criteria pollutant fees set at the higher-end of the range of published damage estimates, but not from criteria pollutant fees based on low or midrange damage estimates. With midrange criteria pollutant fees assessed, SO(2) and NOx emissions are lower than the business as usual case (by 52% and 10%, respectively), with larger differences in the western U.S. than in the eastern U.S. GHG emissions are not significantly impacted by midrange criteria pollutant fees alone; conversely, with only GHG fees, NO(x) emissions are reduced by up to 11%, yet SO(2) emissions are slightly higher than in the business as usual case. Therefore, fees on both GHG and criteria pollutants may be needed to achieve significant reductions in both sets of pollutants.

  7. The estimation of electrical cable fire-induced damage limits

    NASA Astrophysics Data System (ADS)

    Nowlen, S. P.; Jacobus, M. J.

    Sandia National Laboratories has, for several years, been engaged in the performance of both fire safety and electrical equipment qualification research under independent programs sponsored by the US Nuclear Regulatory Commission. Recent comparisons between electrical cable thermal damageability data gathered independently in these two efforts indicate that a direct correlation exists between certain of the recent cable thermal vulnerability information gathered under equipment qualification conditions and thermal damageability in a fire environment. This direct correlation allows for a significant expansion of the data base on estimated cable thermal vulnerability limits in a fire environment because of the wide range of cable types and products that have been evaluated as a part of the equipment qualification research. This paper provides a discussion of the basis for the derived correlation, and presents estimated cable thermal damage limits for a wide range of generic cable types and specific cable products. The supposition that a direct correlation exists is supported through direct comparisons of the test results for certain specific cable products. The proposed supplemental cable fire vulnerability data gained from examination of the equipment qualification results is presented. These results should be of particular interest to those engaged in the evaluation of fire risk for industrial facilities, including nuclear power plants.

  8. Invertebrate herbivory on floating-leaf macrophytes at the northeast of Argentina: should the damage be taken into account in estimations of plant biomass?

    PubMed

    Martínez, Fedra S; Franceschini, Celeste

    2018-01-01

    We assessed the damage produced by invertebrate herbivores per leaf lamina and per m2 of populations floating-leaf macrophytes of Neotropical wetlands in the growth and decay periods, and assessed if the damage produced by the herbivores should be taken into account in the estimations of plant biomass of these macrophytes or not. The biomass removed per lamina and per m2 was higher during the growth period than in decay period in Nymphoides indica and Hydrocleys nymphoides, while Nymphaea prolifera had low values of herbivory in growth period. During decay period this plant is only present as vegetative propagules. According to the values of biomass removed per m2 of N. indica, underestimation up to 17.69% should be produced in cases that herbivory do not should be taking account to evaluate these plant parameters on this macrophyte. Therefore, for the study of biomass and productivity in the study area, we suggest the use of corrected lamina biomass after estimating the biomass removed by herbivores on N. indica. The values of damage in N. indica emphasize the importance of this macrophyte as a food resource for invertebrate herbivores in the trophic networks of the Neotropical wetlands.

  9. Flood risk and cultural heritage: the case study of Florence (Italy)

    NASA Astrophysics Data System (ADS)

    Arrighi, Chiara; Castelli, Fabio; Brugioni, Marcello; Franceschini, Serena; Mazzanti, Bernardo

    2016-04-01

    Cultural heritage plays a key role for communities in terms of both identity and economic value. It is often under serious threat by natural hazards, nevertheless, quantitative assessments of risk are quite uncommon. This work addresses the flood risk assessment to cultural heritage in an exemplary art city, which is Florence, Italy. The risk assessment method here adopted borrows the most common definition of flood risk as the product of hazard, vulnerability and exposure, with some necessary adjustments. The risk estimation is carried out at the building scale for the whole UNESCO site, which coincides with the historical centre of the city. A distinction in macro- and micro-damage categories has been made according to the vulnerability of the objects at risk. Two damage macro-categories are selected namely cultural buildings and contents. Cultural buildings are classified in damage micro-categories as churches/religious complexes, libraries/archives and museums. The damages to the contents are estimated for four micro-categories: paintings, sculptures, books/prints and goldsmith's art. Data from hydraulic simulations for different recurrence scenarios, historical reports of the devastating 1966 flood and the cultural heritage recognition sheets allow estimating and mapping the annual expected number of works of art lost in absence of risk mitigation strategies.

  10. Investigation of the impact of snow removal activities on pavement markings in Virginia.

    DOT National Transportation Integrated Search

    1995-01-01

    Snow removal activities resulted in substantial damage to pavement markings in Virginia over the last 2 years. Typically, the estimates of the extent of pavement marking damage are based on the observations of the staff of the Virginia Department of ...

  11. In Brief: Hidden environment and health costs of energy

    NASA Astrophysics Data System (ADS)

    Showstack, Randy

    2009-10-01

    The hidden costs of energy production and use in the United States amounted to an estimated $120 billion in 2005, according to a 19 October report by the U.S. National Research Council. The report, “Hidden Costs of Energy: Unpriced Consequences of Energy Production and Use,” examines hidden costs, including the cost of air pollution damage to human health, which are not reflected in market prices of energy sources, electricity, or gasoline. The report found that in 2005, the total annual external damages from sulfur dioxide, nitrogen oxides, and particulate matter created by coal-burning power plants that produced 95% of the nation's coal-generated electricity were about $62 billion, with nonclimate damages averaging about 3.2 cents for every kilowatt-hour of energy produced. It is estimated that by 2030, nonclimate damages will fall to 1.7 cents per kilowatt-hour. The 2030 figure assumes that new policies already slated for implementation are put in place.

  12. Intragastric inulin as a measure of mucosal damage caused by aspirin

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wittmers, L.E. Jr.; Anderson, L.A.; Fall, M.M.

    In an attempt to find a method of gastric mucosal damage assessment that yields consistent results, the experiments presented here employed the measurement of the movement of inulin out of the gastric contents into the stomach wall and vascular compartment as an estimate of mucosal damage. Anesthetized male Sprague-Dawley rats were functionally nephrectomized and were administered a control or test solution containing 3H-inulin. The test solutions contained one of three doses of aspirin. Blood samples were taken at 15-min intervals over a 90-min exposure period. The stomach was removed from the animal and full-thickness tissue samples taken for measurement ofmore » 3H-inulin content. When the gastric mucosa was exposed to the test agents, there was a significantly greater accumulation of inulin in the body and antrum as well as in the plasma when compared to controls. We conclude that intragastric inulin can be employed to estimate gastric mucosal damage.« less

  13. Tornado Intensity Estimated from Damage Path Dimensions

    PubMed Central

    Elsner, James B.; Jagger, Thomas H.; Elsner, Ian J.

    2014-01-01

    The Newcastle/Moore and El Reno tornadoes of May 2013 are recent reminders of the destructive power of tornadoes. A direct estimate of a tornado's power is difficult and dangerous to get. An indirect estimate on a categorical scale is available from a post-storm survery of the damage. Wind speed bounds are attached to the scale, but the scale is not adequate for analyzing trends in tornado intensity separate from trends in tornado frequency. Here tornado intensity on a continuum is estimated from damage path length and width, which are measured on continuous scales and correlated to the EF rating. The wind speeds on the EF scale are treated as interval censored data and regressed onto the path dimensions and fatalities. The regression model indicates a 25% increase in expected intensity over a threshold intensity of 29 m s−1 for a 100 km increase in path length and a 17% increase in expected intensity for a one km increase in path width. The model shows a 43% increase in the expected intensity when fatalities are observed controlling for path dimensions. The estimated wind speeds correlate at a level of .77 (.34, .93) [95% confidence interval] with a small sample of wind speeds estimated independently from a doppler radar calibration. The estimated wind speeds allow analyses to be done on the tornado database that are not possible with the categorical scale. The modeled intensities can be used in climatology and in environmental and engineering applications. Research is needed to understand the upward trends in path length and width. PMID:25229242

  14. Tornado intensity estimated from damage path dimensions.

    PubMed

    Elsner, James B; Jagger, Thomas H; Elsner, Ian J

    2014-01-01

    The Newcastle/Moore and El Reno tornadoes of May 2013 are recent reminders of the destructive power of tornadoes. A direct estimate of a tornado's power is difficult and dangerous to get. An indirect estimate on a categorical scale is available from a post-storm survery of the damage. Wind speed bounds are attached to the scale, but the scale is not adequate for analyzing trends in tornado intensity separate from trends in tornado frequency. Here tornado intensity on a continuum is estimated from damage path length and width, which are measured on continuous scales and correlated to the EF rating. The wind speeds on the EF scale are treated as interval censored data and regressed onto the path dimensions and fatalities. The regression model indicates a 25% increase in expected intensity over a threshold intensity of 29 m s(-1) for a 100 km increase in path length and a 17% increase in expected intensity for a one km increase in path width. The model shows a 43% increase in the expected intensity when fatalities are observed controlling for path dimensions. The estimated wind speeds correlate at a level of .77 (.34, .93) [95% confidence interval] with a small sample of wind speeds estimated independently from a doppler radar calibration. The estimated wind speeds allow analyses to be done on the tornado database that are not possible with the categorical scale. The modeled intensities can be used in climatology and in environmental and engineering applications. Research is needed to understand the upward trends in path length and width.

  15. Tempol, a Superoxide Dismutase Mimetic Agent, Ameliorates Cisplatin-Induced Nephrotoxicity through Alleviation of Mitochondrial Dysfunction in Mice

    PubMed Central

    Ahmed, Lamiaa A.; Shehata, Nagwa I.; Abdelkader, Noha F.; Khattab, Mahmoud M.

    2014-01-01

    Background Mitochondrial dysfunction is a crucial mechanism by which cisplatin, a potent chemotherapeutic agent, causes nephrotoxicity where mitochondrial electron transport complexes are shifted mostly toward imbalanced reactive oxygen species versus energy production. In the present study, the protective role of tempol, a membrane-permeable superoxide dismutase mimetic agent, was evaluated on mitochondrial dysfunction and the subsequent damage induced by cisplatin nephrotoxicity in mice. Methods and Findings Nephrotoxicity was assessed 72 h after a single i.p. injection of cisplatin (25 mg/kg) with or without oral administration of tempol (100 mg/kg/day). Serum creatinine and urea as well as glucosuria and proteinuria were evaluated. Both kidneys were isolated for estimation of oxidative stress markers, adenosine triphosphate (ATP) content and caspase-3 activity. Moreover, mitochondrial oxidative phosphorylation capacity, complexes I–IV activities and mitochondrial nitric oxide synthase (mNOS) protein expression were measured along with histological examinations of renal tubular damage and mitochondrial ultrastructural changes. Tempol was effective against cisplatin-induced elevation of serum creatinine and urea as well as glucosuria and proteinuria. Moreover, pretreatment with tempol notably inhibited cisplatin-induced oxidative stress and disruption of mitochondrial function by restoring mitochondrial oxidative phosphorylation, complexes I and III activities, mNOS protein expression and ATP content. Tempol also provided significant protection against apoptosis, tubular damage and mitochondrial ultrastructural changes. Interestingly, tempol did not interfere with the cytotoxic effect of cisplatin against the growth of solid Ehrlich carcinoma. Conclusion This study highlights the potential role of tempol in inhibiting cisplatin-induced nephrotoxicity without affecting its antitumor activity via amelioration of oxidative stress and mitochondrial dysfunction. PMID:25271439

  16. Use of Citizen Science and Social Media to Improve Wind Hazard and Damage Characterization

    NASA Astrophysics Data System (ADS)

    Lombardo, F.; Meidani, H.

    2017-12-01

    Windstorm losses are significant in the U.S. annually and cause damage worldwide. A large percentage of losses are caused by localized events (e.g., tornadoes). In order to better mitigate these losses improvement is needed in understanding the hazard characteristics and physical damage. However, due to the small-scale nature of these events the resolution of the dedicated measuring network does not capture most occurrences. As a result damage-based assessments are sometimes used to gauge intensity. These damage assessments often suffer from a lack of available manpower, inability to arrive at the scene rapidly and difficulty accessing a damaged site. The use and rapid dissemination of social media, the power of crowds engaged in scientific endeavors, and the public's awareness of their vulnerabilities point to a paradigm shift in how hazards can be sensed in a rapid manner. In this way, `human-sensor' data has the potential to radically improve fundamental understanding of hazard and disasters and resolve some of the existing challenges in wind hazard and damage characterization. Data from social media outlets such as Twitter have been used to aid in damage assessments from hazards such as flood and earthquake, however, the reliability and uncertainty of participatory sensing has been questioned and has been called the `biggest challenge' for its sustained use. This research proposes to investigate the efficacy of both citizen science applications and social media data to represent wind hazards and associated damage. Research has focused on a two-phase approach: 1) to have citizen scientists perform their own `damage survey' (i.e., questionnaire) with known damage to assess uncertainty in estimation and 2) downloading and analysis of social media text and imagery streams to ascertain the possibility of performing `unstructured damage surveys'. Early results have shown that the untrained public can estimate tornado damage levels in residential structures with some accuracy. In addition, valuable windstorm hazard and damage information in both text and imagery can be extracted and archived from Twitter in an automated fashion. Information extracted from these sources will feed into advances in hazard and disaster modeling, social-cognitive theories of human behavior and decision-making for hazard mitigation.

  17. Post-Disaster Damage Assessment using Remotely Sensed Data for Post Disaster Needs Assessments: Pakistan and Nigeria case studies

    NASA Astrophysics Data System (ADS)

    Saito, Keiko; Lemoine, Guido; Dell'Oro, Luca; Pedersen, Wendi; Nunez-Gomez, Ariel; Dalmasso, Simone; Balbo, Simone; Louvrier, Christophe; Caravaggi, Ivano; de Groeve, Tom; Slayback, Dan; Policelli, Frederick; Brakenridge, Bob; Rashid, Kashif; Gad, Sawsan; Arshad, Raja; Wielinga, Doekle; Parvez, Ayaz; Khan, Haris

    2013-04-01

    Since the launch of high-resolution optical satellites in 1999, remote sensing has increasingly been used in the context of post-disaster damage assessments worldwide. In the immediate aftermath of a natural disaster, particularly when extensive geographical areas are affected, it is often difficult to determine the extent and magnitude of disaster impacts. The Global Facility for Disaster Reduction and Recovery (GFDRR) has been leading efforts to utilise remote sensing techniques during disasters, starting with the 2010 Haiti earthquake. However, remote sensing has mostly been applied to extensive flood events in the context of developing Post-Disaster Needs Assessments (PDNAs). Given that worldwide, floods were the most frequent type of natural disasters between 2000 and 2011, affecting 106 million people in 2011 alone (EM-DAT) , there is clearly significant potential for on-going use of remote sensing techniques. Two case studies will be introduced here, the 2010 Pakistan flood and the 2012 Nigeria flood. The typical approach is to map the maximum cumulative inundation extent, then overlay this hazard information with available exposure datasets. The PDNA methodology itself is applied to a maximum of 15 sectors, of which remote sensing is most useful for housing, agriculture, transportation. Environment and irrigation could be included but these sectors were not covered in these events. The maximum cumulative flood extent is determined using remotely sensed data led by in-country agencies together with international organizations. To enhance this process, GFDRR hosted a SPRINT event in 2012 to tailor daily flood maps derived from MODIS imagery by NASA Goddard's Office of Applied Sciences to this purpose. To estimate the (direct) damage, exposure data for each sector is required. Initially global datasets are used, but these may be supplemented by national level datasets to revise damage estimates, depending on availability. Remote sensed estimates of direct damage are used to confirm field estimates of the magnitude of the damage; thus, the speed of assessment can be balanced not having to achieve high accuracy results. In the future, to increase the speed of remote sensed damage assessments, there is a need for existing exposure information - which can also be used for risk prediction as well as disaster response. However, advances in this area vary significantly by country and sector and therefore efforts to move this agenda forward will significantly improve disaster reduction and recovery.

  18. Development and evaluation of an ozone deposition scheme for coupling to a terrestrial biosphere model

    NASA Astrophysics Data System (ADS)

    Franz, Martina; Simpson, David; Arneth, Almut; Zaehle, Sönke

    2017-01-01

    Ozone (O3) is a toxic air pollutant that can damage plant leaves and substantially affect the plant's gross primary production (GPP) and health. Realistic estimates of the effects of tropospheric anthropogenic O3 on GPP are thus potentially important to assess the strength of the terrestrial biosphere as a carbon sink. To better understand the impact of ozone damage on the terrestrial carbon cycle, we developed a module to estimate O3 uptake and damage of plants for a state-of-the-art global terrestrial biosphere model called OCN. Our approach accounts for ozone damage by calculating (a) O3 transport from 45 m height to leaf level, (b) O3 flux into the leaf, and (c) ozone damage of photosynthesis as a function of the accumulated O3 uptake over the lifetime of a leaf. A comparison of modelled canopy conductance, GPP, and latent heat to FLUXNET data across European forest and grassland sites shows a general good performance of OCN including ozone damage. This comparison provides a good baseline on top of which ozone damage can be evaluated. In comparison to literature values, we demonstrate that the new model version produces realistic O3 surface resistances, O3 deposition velocities, and stomatal to total O3 flux ratios. A sensitivity study reveals that key metrics of the air-to-leaf O3 transport and O3 deposition, in particular the stomatal O3 uptake, are reasonably robust against uncertainty in the underlying parameterisation of the deposition scheme. Nevertheless, correctly estimating canopy conductance plays a pivotal role in the estimate of cumulative O3 uptake. We further find that accounting for stomatal and non-stomatal uptake processes substantially affects simulated plant O3 uptake and accumulation, because aerodynamic resistance and non-stomatal O3 destruction reduce the predicted leaf-level O3 concentrations. Ozone impacts on GPP and transpiration in a Europe-wide simulation indicate that tropospheric O3 impacts the regional carbon and water cycling less than expected from previous studies. This study presents a first step towards the integration of atmospheric chemistry and ecosystem dynamics modelling, which would allow for assessing the wider feedbacks between vegetation ozone uptake and tropospheric ozone burden.

  19. A synthesis of regional inputs and damage costs of reactive nitrogen in the United States

    EPA Science Inventory

    We estimated the fate of N in crops and in the environment (air, land, freshwater, groundwater, and coastal zones) with published coefficients describing nutrient uptake efficiency, gaseous emissions, and leaching losses. Benefits and damage costs of anthropogenic N inputs were ...

  20. Model-based damage evaluation of layered CFRP structures

    NASA Astrophysics Data System (ADS)

    Munoz, Rafael; Bochud, Nicolas; Rus, Guillermo; Peralta, Laura; Melchor, Juan; Chiachío, Juan; Chiachío, Manuel; Bond, Leonard J.

    2015-03-01

    An ultrasonic evaluation technique for damage identification of layered CFRP structures is presented. This approach relies on a model-based estimation procedure that combines experimental data and simulation of ultrasonic damage-propagation interactions. The CFPR structure, a [0/90]4s lay-up, has been tested in an immersion through transmission experiment, where a scan has been performed on a damaged specimen. Most ultrasonic techniques in industrial practice consider only a few features of the received signals, namely, time of flight, amplitude, attenuation, frequency contents, and so forth. In this case, once signals are captured, an algorithm is used to reconstruct the complete signal waveform and extract the unknown damage parameters by means of modeling procedures. A linear version of the data processing has been performed, where only Young modulus has been monitored and, in a second nonlinear version, the first order nonlinear coefficient β was incorporated to test the possibility of detection of early damage. The aforementioned physical simulation models are solved by the Transfer Matrix formalism, which has been extended from linear to nonlinear harmonic generation technique. The damage parameter search strategy is based on minimizing the mismatch between the captured and simulated signals in the time domain in an automated way using Genetic Algorithms. Processing all scanned locations, a C-scan of the parameter of each layer can be reconstructed, obtaining the information describing the state of each layer and each interface. Damage can be located and quantified in terms of changes in the selected parameter with a measurable extension. In the case of the nonlinear coefficient of first order, evidence of higher sensitivity to damage than imaging the linearly estimated Young Modulus is provided.

  1. PPD-induced monocyte mitochondrial damage is associated with a protective effect to develop tuberculosis in BCG vaccinated individuals: A cohort study.

    PubMed

    Marín, Diana; Marín, Nancy; Del Corral, Helena; López, Lucelly; Ramirez-Agudelo, María Elena; Rojas, Carlos A; Arbeláez, María P; García, Luis F; Rojas, Mauricio

    2017-01-01

    The mechanisms of mononuclear phagocyte death have been associated with the permissiveness and resistance to mycobacterial replication, but it remains unknown whether or not they help predict the risk of developing TB. To describe the factors associated with the induction of monocyte mitochondrial and membrane damage in response to PPD as well as determine if this type of damage might predict the susceptibility of developing active tuberculosis in a cohort of household contacts (HHCs) from Medellin, Colombia from 2005 to 2008. The prospective cohort study contains 2060 HHCs patients with pulmonary tuberculosis who were meticulously followed for two years. A survey of the socio-demographic, clinical, epidemiological factors and blood samples were collected. Mononuclear cell cultures were stimulated with or without PPD and the type of monocyte death was determined by the flow of cytometry, an indicator was also used for its analysis. Logistic regression was adjusted by the Generalized Estimations Equations and the survival was estimated with the Kaplan-Meier and Cox regression. Confidence intervals were used for estimating the association. 1,859 out of 2,060 blood samples of the HHCs patients analyzed showed monocyte death. In response to PPD, 83.4% underwent mitochondrial damage while 50.9% had membrane damage. The membrane damage in response to PPD was higher in children under 4 years (OR: 1.57; (95% CI: 1.1 to 2.4) and the HHCs who slept regularly in the same household has an index case of (OR: 1.54; 95% CI: 1.0 to 2.3). After adjustment by age, comorbidities, nutritional status, proximity to index case and overcrowding, the risk of developing active TB among BCG vaccinated HHCs individuals with induction of mitochondrial damage was HR = 0.19 (95% CI: 0.1 to 0.5). The induction of monocytes mitochondrial damage by PPD stimulation correlates with protection of TB disease development in BCG-vaccinated HHCs. This represents a potential tool to predict susceptibility of developing active disease in this population.

  2. Multi-hazard risk analysis related to hurricanes

    NASA Astrophysics Data System (ADS)

    Lin, Ning

    Hurricanes present major hazards to the United States. Associated with extreme winds, heavy rainfall, and storm surge, landfalling hurricanes often cause enormous structural damage to coastal regions. Hurricane damage risk assessment provides the basis for loss mitigation and related policy-making. Current hurricane risk models, however, often oversimplify the complex processes of hurricane damage. This dissertation aims to improve existing hurricane risk assessment methodology by coherently modeling the spatial-temporal processes of storm landfall, hazards, and damage. Numerical modeling technologies are used to investigate the multiplicity of hazards associated with landfalling hurricanes. The application and effectiveness of current weather forecasting technologies to predict hurricane hazards is investigated. In particular, the Weather Research and Forecasting model (WRF), with Geophysical Fluid Dynamics Laboratory (GFDL)'s hurricane initialization scheme, is applied to the simulation of the wind and rainfall environment during hurricane landfall. The WRF model is further coupled with the Advanced Circulation (AD-CIRC) model to simulate storm surge in coastal regions. A case study examines the multiple hazards associated with Hurricane Isabel (2003). Also, a risk assessment methodology is developed to estimate the probability distribution of hurricane storm surge heights along the coast, particularly for data-scarce regions, such as New York City. This methodology makes use of relatively simple models, specifically a statistical/deterministic hurricane model and the Sea, Lake and Overland Surges from Hurricanes (SLOSH) model, to simulate large numbers of synthetic surge events, and conducts statistical analysis. The estimation of hurricane landfall probability and hazards are combined with structural vulnerability models to estimate hurricane damage risk. Wind-induced damage mechanisms are extensively studied. An innovative windborne debris risk model is developed based on the theory of Poisson random measure, substantiated by a large amount of empirical data. An advanced vulnerability assessment methodology is then developed, by integrating this debris risk model and a component-based pressure damage model, to predict storm-specific or annual damage to coastal residential neighborhoods. The uniqueness of this vulnerability model lies in its detailed description of the interaction between wind pressure and windborne debris effects over periods of strong winds, which is a major mechanism leading to structural failures during hurricanes.

  3. Uncertainty analysis of practical structural health monitoring systems currently employed for tall buildings consisting of small number of sensors

    NASA Astrophysics Data System (ADS)

    Hirai, Kenta; Mita, Akira

    2016-04-01

    Because of social background, such as repeated large earthquakes and cheating in design and construction, structural health monitoring (SHM) systems are getting strong attention. The SHM systems are in a practical phase. An SHM system consisting of small number of sensors has been introduced to 6 tall buildings in Shinjuku area. Including them, there are 2 major issues in the SHM systems consisting of small number of sensors. First, optimal system number of sensors and the location are not well-defined. In the practice, system placement is determined based on rough prediction and experience. Second, there are some uncertainties in estimation results by the SHM systems. Thus, the purpose of this research is to provide useful information for increasing reliability of SHM system and to improve estimation results based on uncertainty analysis of the SHM systems. The important damage index used here is the inter-story drift angle. The uncertainty considered here are number of sensors, earthquake motion characteristics, noise in data, error between numerical model and real building, nonlinearity of parameter. Then I have analyzed influence of each factor to estimation accuracy. The analysis conducted here will help to decide sensor system design considering valance of cost and accuracy. Because of constraint on the number of sensors, estimation results by the SHM system has tendency to provide smaller values. To overcome this problem, a compensation algorithm was discussed and presented. The usefulness of this compensation method was demonstrated for 40 story S and RC building models with nonlinear response.

  4. A Comprehensive Review on Clinical Applications of Comet Assay

    PubMed Central

    Gunasekarana, Vidya; Chand, Parkash

    2015-01-01

    Increased levels of DNA damage and ineffective repair mechanisms are the underlying bio-molecular events in the pathogenesis of most of the life-threatening diseases like cancer and degenerative diseases. The sources of DNA damage can be either exogenous or endogenous in origin. Imbalance between the oxidants and antioxidants resulting in increased reactive oxygen species mostly accounts for the endogenously derived attacks on DNA. Among the various methods employed in the estimation of DNA damage, alkaline comet assay is proven to be a relatively simple and versatile tool in the assessment of DNA damage and also in determining the efficacy of DNA repair mechanism. The aim of this article is to review the application of comet assay in the field of medicine towards human biomonitoring, understanding the pathogenesis of cancer and progression of chronic and degenerative diseases, prediction of tumour radio & chemosensitivity and in male infertility. A standardized protocol and analysis system of various variants of comet assay in different types of cells, across the labs will be of useful and reliable clinical tool in the field of Medicine for the estimation of levels of DNA damage and repair mechanisms. PMID:25954633

  5. Does it make sense to modify tropical cyclones? A decision-analytic assessment.

    PubMed

    Klima, Kelly; Morgan, M Granger; Grossmann, Iris; Emanuel, Kerry

    2011-05-15

    Recent dramatic increases in damages caused by tropical cyclones (TCs) and improved understanding of TC physics have led DHS to fund research on intentional hurricane modification. We present a decision analytic assessment of whether it is potentially cost-effective to attempt to lower the wind speed of TCs approaching South Florida by reducing sea surface temperatures with wind-wave pumps. Using historical data on hurricanes approaching South Florida, we develop prior probabilities of how storms might evolve. The effects of modification are estimated using a modern TC model. The FEMA HAZUS-MH MR3 damage model and census data on the value of property at risk are used to estimate expected economic losses. We compare wind damages after storm modification with damages after implementing hardening strategies protecting buildings. We find that if it were feasible and properly implemented, modification could reduce net losses from an intense storm more than hardening structures. However, hardening provides "fail safe" protection for average storms that might not be achieved if the only option were modification. The effect of natural variability is larger than that of either strategy. Damage from storm surge is modest in the scenario studied but might be abated by modification.

  6. Gaussian process regression of chirplet decomposed ultrasonic B-scans of a simulated design case

    NASA Astrophysics Data System (ADS)

    Wertz, John; Homa, Laura; Welter, John; Sparkman, Daniel; Aldrin, John

    2018-04-01

    The US Air Force seeks to implement damage tolerant lifecycle management of composite structures. Nondestructive characterization of damage is a key input to this framework. One approach to characterization is model-based inversion of the ultrasonic response from damage features; however, the computational expense of modeling the ultrasonic waves within composites is a major hurdle to implementation. A surrogate forward model with sufficient accuracy and greater computational efficiency is therefore critical to enabling model-based inversion and damage characterization. In this work, a surrogate model is developed on the simulated ultrasonic response from delamination-like structures placed at different locations within a representative composite layup. The resulting B-scans are decomposed via the chirplet transform, and a Gaussian process model is trained on the chirplet parameters. The quality of the surrogate is tested by comparing the B-scan for a delamination configuration not represented within the training data set. The estimated B-scan has a maximum error of ˜15% for an estimated reduction in computational runtime of ˜95% for 200 function calls. This considerable reduction in computational expense makes full 3D characterization of impact damage tractable.

  7. Caloric restriction or telmisartan control dyslipidemia and nephropathy in obese diabetic Zücker rats

    PubMed Central

    2014-01-01

    Background The obese Zücker diabetic fatty male rat (ZDF:Gmi™-fa) is an animal model of type II diabetes associated with obesity and related metabolic disturbances like dyslipidaemia and diabetic nephropathy. In addition, diabetic dyslipidaemia has been linked to vascular and glomerular damage too. Dietary fat restriction is a current strategy to tackle obesity and, telmisartan, as a renoprotective agent, may mediate cholesterol efflux by activating PPARγ. To test the hypothesis that both therapeutical alternatives may influence dyslipidaemia and nephropathy in the ZDF rat, we studied their effect on development of diabetes. Methods Male Zücker Diabetic Fatty (ZDF) rats received a low-calorie diet, vehicle or telmisartan for 9 weeks. Blood samples were obtained for analyses of lipids and lipoproteins, LDL-oxidisability, HDL structural and functional properties. Urinalysis was carried out to estimate albumin loss. At the end of the experimental period, rats were sacrificed, liver extracted and APOA1 mRNA quantified. Results Results indicated that low-calorie diet and telmisartan can slower the onset of overt hyperglycaemia and renal damage assessed as albuminuria. Both interventions decreased the oxidative susceptibility of LDL and hepatic APOA1 mRNA expression but only dietary restriction lowered hyperlipidaemia. Conclusion Either a dietary or pharmacologic interventions with telmisartan have important beneficial effects in terms of LDL oxidative susceptibility and progression of albuminuria in obesity related type II diabetes. PMID:24468233

  8. Hurricane modification and adaptation in Miami-Dade County, Florida.

    PubMed

    Klima, Kelly; Lin, Ning; Emanuel, Kerry; Morgan, M Granger; Grossmann, Iris

    2012-01-17

    We investigate tropical cyclone wind and storm surge damage reduction for five areas along the Miami-Dade County coastline either by hardening buildings or by the hypothetical application of wind-wave pumps to modify storms. We calculate surge height and wind speed as functions of return period and sea surface temperature reduction by wind-wave pumps. We then estimate costs and economic losses with the FEMA HAZUS-MH MR3 damage model and census data on property at risk. All areas experience more surge damages for short return periods, and more wind damages for long periods. The return period at which the dominating hazard component switches depends on location. We also calculate the seasonal expected fraction of control damage for different scenarios to reduce damages. Surge damages are best reduced through a surge barrier. Wind damages are best reduced by a portfolio of techniques that, assuming they work and are correctly deployed, include wind-wave pumps.

  9. Estimating timber losses from a town ant colony with aerial photographs

    Treesearch

    John C. Moser

    1986-01-01

    Aerial photographs were used to locate an individual nest of Atta texana (Buckley) and to estimate the area of damage in a plantation of loblolly pine (Pinus taeda L.). Stumpage loss from the nest over a period of 30 years was estimated to be $653.

  10. Estimated damage from the Cascadia Subduction Zone tsunami: A model comparisons using fragility curves

    NASA Astrophysics Data System (ADS)

    Wiebe, D. M.; Cox, D. T.; Chen, Y.; Weber, B. A.; Chen, Y.

    2012-12-01

    Building damage from a hypothetical Cascadia Subduction Zone tsunami was estimated using two methods and applied at the community scale. The first method applies proposed guidelines for a new ASCE 7 standard to calculate the flow depth, flow velocity, and momentum flux from a known runup limit and estimate of the total tsunami energy at the shoreline. This procedure is based on a potential energy budget, uses the energy grade line, and accounts for frictional losses. The second method utilized numerical model results from previous studies to determine maximum flow depth, velocity, and momentum flux throughout the inundation zone. The towns of Seaside and Canon Beach, Oregon, were selected for analysis due to the availability of existing data from previously published works. Fragility curves, based on the hydrodynamic features of the tsunami flow (inundation depth, flow velocity, and momentum flux) and proposed design standards from ASCE 7 were used to estimate the probability of damage to structures located within the inundations zone. The analysis proceeded at the parcel level, using tax-lot data to identify construction type (wood, steel, and reinforced-concrete) and age, which was used as a performance measure when applying the fragility curves and design standards. The overall probability of damage to civil buildings was integrated for comparison between the two methods, and also analyzed spatially for damage patterns, which could be controlled by local bathymetric features. The two methods were compared to assess the sensitivity of the results to the uncertainty in the input hydrodynamic conditions and fragility curves, and the potential advantages of each method discussed. On-going work includes coupling the results of building damage and vulnerability to an economic input output model. This model assesses trade between business sectors located inside and outside the induction zone, and is used to measure the impact to the regional economy. Results highlight critical businesses sectors and infrastructure critical to the economic recovery effort, which could be retrofitted or relocated to survive the event. The results of this study improve community understanding of the tsunami hazard for civil buildings.

  11. Protective Effect of Hydroxychloroquine on Renal Damage in Patients with Lupus Nephritis: Data from LUMINA, a Multiethnic U.S. Cohort

    PubMed Central

    Pons-Estel, Guillermo J.; Alarcón, Graciela S.; McGwin, Gerald; Danila, Maria I.; Zhang, Jie; Bastian, Holly M.; Reveille, John D.; Vilá, Luis M.

    2010-01-01

    Objective To assess if hydroxychloroquine can delay renal damage development in lupus nephritis patients. Methods Lupus nephritis patients (n=256) from LUMINA (n=635), a multiethnic cohort of African Americans, Hispanics and Caucasians, age ≥16 years, disease duration ≤5 years at baseline (T0) were studied. Renal damage was defined per the SLICC Damage Index (≥1 of the following lasting at least six months: estimated/measured glomerular filtration rate <50%, 24-hour proteinuria ≥3.5 g and/or end-stage renal disease, regardless of dialysis or transplantation). Patients with renal damage before T0 were excluded (n=53). The association between hydroxychloroquine use and renal damage (as defined, or omitting proteinuria) was estimated using Cox proportional regression analyses adjusting for potentially confounders. Kaplan-Meier survival curves based on hydroxychloroquine intake or World Health Organization (WHO) Class glomerulonephritis were also derived. Results Sixty-three (31.0%) of 203 patients developed renal damage over a mean (standard deviation) disease duration of 5.2 (3.5) years. The most frequent renal damage domain item was proteinuria. Hydroxychloroquine-takers (79.3%) exhibited a lower frequency of WHO Class IV glomerulonephritis, lower disease activity and received lower glucocorticoid doses than non-takers. After adjusting for confounders, hydroxychloroquine was protective of renal damage occurrence in full (HR=0.12; 95% CI 0.02-0.97; p=0.0464) and reduced (HR=0.29; 95%CI 0.13-0.68; p=0.0043) models. Omitting proteinuria provided comparable results. The cumulative probability of renal damage occurrence was higher in hydroxychloroquine non-takers and in WHO Class IV glomerulonephritis (p<0.0001). Conclusions After adjusting for possible confounding factors the protective effect of hydroxychloroquine in retarding renal damage occurrence in SLE is still evident. PMID:19479701

  12. Building vulnerability to hydro-geomorphic hazards: Estimating damage probability from qualitative vulnerability assessment using logistic regression

    NASA Astrophysics Data System (ADS)

    Ettinger, Susanne; Mounaud, Loïc; Magill, Christina; Yao-Lafourcade, Anne-Françoise; Thouret, Jean-Claude; Manville, Vern; Negulescu, Caterina; Zuccaro, Giulio; De Gregorio, Daniela; Nardone, Stefano; Uchuchoque, Juan Alexis Luque; Arguedas, Anita; Macedo, Luisa; Manrique Llerena, Nélida

    2016-10-01

    The focus of this study is an analysis of building vulnerability through investigating impacts from the 8 February 2013 flash flood event along the Avenida Venezuela channel in the city of Arequipa, Peru. On this day, 124.5 mm of rain fell within 3 h (monthly mean: 29.3 mm) triggering a flash flood that inundated at least 0.4 km2 of urban settlements along the channel, affecting more than 280 buildings, 23 of a total of 53 bridges (pedestrian, vehicle and railway), and leading to the partial collapse of sections of the main road, paralyzing central parts of the city for more than one week. This study assesses the aspects of building design and site specific environmental characteristics that render a building vulnerable by considering the example of a flash flood event in February 2013. A statistical methodology is developed that enables estimation of damage probability for buildings. The applied method uses observed inundation height as a hazard proxy in areas where more detailed hydrodynamic modeling data is not available. Building design and site-specific environmental conditions determine the physical vulnerability. The mathematical approach considers both physical vulnerability and hazard related parameters and helps to reduce uncertainty in the determination of descriptive parameters, parameter interdependency and respective contributions to damage. This study aims to (1) enable the estimation of damage probability for a certain hazard intensity, and (2) obtain data to visualize variations in damage susceptibility for buildings in flood prone areas. Data collection is based on a post-flood event field survey and the analysis of high (sub-metric) spatial resolution images (Pléiades 2012, 2013). An inventory of 30 city blocks was collated in a GIS database in order to estimate the physical vulnerability of buildings. As many as 1103 buildings were surveyed along the affected drainage and 898 buildings were included in the statistical analysis. Univariate and bivariate analyses were applied to better characterize each vulnerability parameter. Multiple corresponding analyses revealed strong relationships between the "Distance to channel or bridges", "Structural building type", "Building footprint" and the observed damage. Logistic regression enabled quantification of the contribution of each explanatory parameter to potential damage, and determination of the significant parameters that express the damage susceptibility of a building. The model was applied 200 times on different calibration and validation data sets in order to examine performance. Results show that 90% of these tests have a success rate of more than 67%. Probabilities (at building scale) of experiencing different damage levels during a future event similar to the 8 February 2013 flash flood are the major outcomes of this study.

  13. Detecting background changes in environments with dynamic foreground by separating probability distribution function mixtures using Pearson's method of moments

    NASA Astrophysics Data System (ADS)

    Jenkins, Colleen; Jordan, Jay; Carlson, Jeff

    2007-02-01

    This paper presents parameter estimation techniques useful for detecting background changes in a video sequence with extreme foreground activity. A specific application of interest is automated detection of the covert placement of threats (e.g., a briefcase bomb) inside crowded public facilities. We propose that a histogram of pixel intensity acquired from a fixed mounted camera over time for a series of images will be a mixture of two Gaussian functions: the foreground probability distribution function and background probability distribution function. We will use Pearson's Method of Moments to separate the two probability distribution functions. The background function can then be "remembered" and changes in the background can be detected. Subsequent comparisons of background estimates are used to detect changes. Changes are flagged to alert security forces to the presence and location of potential threats. Results are presented that indicate the significant potential for robust parameter estimation techniques as applied to video surveillance.

  14. Flood Damage and Loss Estimation for Iowa on Web-based Systems using HAZUS

    NASA Astrophysics Data System (ADS)

    Yildirim, E.; Sermet, M. Y.; Demir, I.

    2016-12-01

    Importance of decision support systems for flood emergency response and loss estimation increases with its social and economic impacts. To estimate the damage of the flood, there are several software systems available to researchers and decision makers. HAZUS-MH is one of the most widely used desktop program, developed by FEMA (Federal Emergency Management Agency), to estimate economic loss and social impacts of disasters such as earthquake, hurricane and flooding (riverine and coastal). HAZUS used loss estimation methodology and implements through geographic information system (GIS). HAZUS contains structural, demographic, and vehicle information across United States. Thus, it allows decision makers to understand and predict possible casualties and damage of the floods by running flood simulations through GIS application. However, it doesn't represent real time conditions because of using static data. To close this gap, an overview of a web-based infrastructure coupling HAZUS and real time data provided by IFIS (Iowa Flood Information System) is presented by this research. IFIS is developed by the Iowa Flood Center, and a one-stop web-platform to access community-based flood conditions, forecasts, visualizations, inundation maps and flood-related data, information, and applications. Large volume of real-time observational data from a variety of sensors and remote sensing resources (radars, rain gauges, stream sensors, etc.) and flood inundation models are staged on a user-friendly maps environment that is accessible to the general public. Providing cross sectional analyses between HAZUS-MH and IFIS datasets, emergency managers are able to evaluate flood damage during flood events easier and more accessible in real time conditions. With matching data from HAZUS-MH census tract layer and IFC gauges, economical effects of flooding can be observed and evaluated by decision makers. The system will also provide visualization of the data by using augmented reality for see-through displays. Emergency management experts can take advantage of this visualization mode to manage flood response activities in real time. Also, forecast system developed by the Iowa Flood Center will be used to predict probable damage of the flood.

  15. Neutron radiation damage studies in the structural materials of a 500 MWe fast breeder reactor using DPA cross-sections from ENDF / B-VII.1

    NASA Astrophysics Data System (ADS)

    Saha, Uttiyoarnab; Devan, K.; Bachchan, Abhitab; Pandikumar, G.; Ganesan, S.

    2018-04-01

    The radiation damage in the structural materials of a 500 MWe Indian prototype fast breeder reactor (PFBR) is re-assessed by computing the neutron displacement per atom (dpa) cross-sections from the recent nuclear data library evaluated by the USA, ENDF / B-VII.1, wherein revisions were taken place in the new evaluations of basic nuclear data because of using the state-of-the-art neutron cross-section experiments, nuclear model-based predictions and modern data evaluation techniques. An indigenous computer code, computation of radiation damage (CRaD), is developed at our centre to compute primary-knock-on atom (PKA) spectra and displacement cross-sections of materials both in point-wise and any chosen group structure from the evaluated nuclear data libraries. The new radiation damage model, athermal recombination-corrected displacement per atom (arc-dpa), developed based on molecular dynamics simulations is also incorporated in our study. This work is the result of our earlier initiatives to overcome some of the limitations experienced while using codes like RECOIL, SPECTER and NJOY 2016, to estimate radiation damage. Agreement of CRaD results with other codes and ASTM standard for Fe dpa cross-section is found good. The present estimate of total dpa in D-9 steel of PFBR necessitates renormalisation of experimental correlations of dpa and radiation damage to ensure consistency of damage prediction with ENDF / B-VII.1 library.

  16. Real-Time Airborne Gamma-Ray Background Estimation Using NASVD with MLE and Radiation Transport for Calibration

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kulisek, Jonathan A.; Schweppe, John E.; Stave, Sean C.

    2015-06-01

    Helicopter-mounted gamma-ray detectors can provide law enforcement officials the means to quickly and accurately detect, identify, and locate radiological threats over a wide geographical area. The ability to accurately distinguish radiological threat-generated gamma-ray signatures from background gamma radiation in real time is essential in order to realize this potential. This problem is non-trivial, especially in urban environments for which the background may change very rapidly during flight. This exacerbates the challenge of estimating background due to the poor counting statistics inherent in real-time airborne gamma-ray spectroscopy measurements. To address this, we have developed a new technique for real-time estimation ofmore » background gamma radiation from aerial measurements. This method is built upon on the noise-adjusted singular value decomposition (NASVD) technique that was previously developed for estimating the potassium (K), uranium (U), and thorium (T) concentrations in soil post-flight. The method can be calibrated using K, U, and T spectra determined from radiation transport simulations along with basis functions, which may be determined empirically by applying maximum likelihood estimation (MLE) to previously measured airborne gamma-ray spectra. The method was applied to both measured and simulated airborne gamma-ray spectra, with and without man-made radiological source injections. Compared to schemes based on simple averaging, this technique was less sensitive to background contamination from the injected man-made sources and may be particularly useful when the gamma-ray background frequently changes during the course of the flight.« less

  17. TEM observations of radiation damage in tungsten irradiated by 20 MeV W ions

    NASA Astrophysics Data System (ADS)

    Ciupiński, Ł.; Ogorodnikova, O. V.; Płociński, T.; Andrzejczuk, M.; Rasiński, M.; Mayer, M.; Kurzydłowski, K. J.

    2013-12-01

    Polycrystalline, recrystallized W targets were subjected to implantation with 20 MeV W6+ ions in order to simulate radiation damage caused by fusion neutrons. Three samples with cumulative damage of 0.01, 0.1 and 0.89 dpa were produced. The near-surface zone of each sample has been analyzed by transmission electron microscopy (TEM). To this end, lamellae oriented perpendicularly to the targets implanted surface were milled out using focused ion beam (FIB). A reference lamella from non-irradiated, recrystallized W target was also prepared to estimate the damage introduced during FIB processing. TEM studies revealed a complex microstructure of the damaged zones as well as its evolution with cumulative damage level. The experimentally observed damage depth agrees very well with the one calculated using the Stopping and Range of Ions in Matter (SRIM) software.

  18. Fusion of real-time simulation, sensing, and geo-informatics in assessing tsunami impact

    NASA Astrophysics Data System (ADS)

    Koshimura, S.; Inoue, T.; Hino, R.; Ohta, Y.; Kobayashi, H.; Musa, A.; Murashima, Y.; Gokon, H.

    2015-12-01

    Bringing together state-of-the-art high-performance computing, remote sensing and spatial information sciences, we establish a method of real-time tsunami inundation forecasting, damage estimation and mapping to enhance disaster response. Right after a major (near field) earthquake is triggered, we perform a real-time tsunami inundation forecasting with use of high-performance computing platform (Koshimura et al., 2014). Using Tohoku University's vector supercomputer, we accomplished "10-10-10 challenge", to complete tsunami source determination in 10 minutes, tsunami inundation modeling in 10 minutes with 10 m grid resolution. Given the maximum flow depth distribution, we perform quantitative estimation of exposed population using census data and mobile phone data, and the numbers of potential death and damaged structures by applying tsunami fragility curve. After the potential tsunami-affected areas are estimated, the analysis gets focused and moves on to the "detection" phase using remote sensing. Recent advances of remote sensing technologies expand capabilities of detecting spatial extent of tsunami affected area and structural damage. Especially, a semi-automated method to estimate building damage in tsunami affected areas is developed using pre- and post-event high-resolution SAR (Synthetic Aperture Radar) data. The method is verified through the case studies in the 2011 Tohoku and other potential tsunami scenarios, and the prototype system development is now underway in Kochi prefecture, one of at-risk coastal city against Nankai trough earthquake. In the trial operation, we verify the capability of the method as a new tsunami early warning and response system for stakeholders and responders.

  19. Estimating Losses from Volcanic Ash in case of a Mt. Baekdu Eruption

    NASA Astrophysics Data System (ADS)

    Yu, Soonyoung; Yoon, Seong-Min; Kim, Sung-Wook; Choi, Eun-Kyeong

    2014-05-01

    We will present the preliminary result of economic losses in South Korea in case of a Mt. Baedu eruption. The Korean peninsula has Mt. Baekdu in North Korea, which will soon enter an active phase, according to volcanologists. The anticipated eruption will be explosive given the viscous and grassy silica-rich magma, and is expected to be one of the largest in recent millennia. We aim to assess the impacts of this eruption to South Korea and help government prepare for the volcanic disasters. In particular, the economic impact from volcanic ash is estimated given the distance from Mt. Baedu to South Korea. In order to scientifically estimate losses from volcanic ash, we need volcanic ash thickness, inventory database, and damage functions between ash thickness and damage ratios for each inventory item. We use the volcanic ash thickness calculated by other research groups in Korea, and they estimated the ash thickness for each eruption scenario using average wind fields. Damage functions are built using the historical damage data in the world, and inventory database is obtained from available digital maps in Korea. According to the preliminary results, the economic impact from volcanic ash is not significant because the ash is rarely deposited in South Korea under general weather conditions. However, the ash can impact human health and environment. Also worst case scenarios can have the significant economic impacts in Korea, and may result in global issues. Acknowledgement: This research was supported by a grant [NEMA-BAEKDUSAN-2012-1-3] from the Volcanic Disaster Preparedness Research Center sponsored by National Emergency Management Agency of Korea.

  20. Land Cover Mapping using GEOBIA to Estimate Loss of Salacca zalacca Trees in Landslide Area of Clapar, Madukara District of Banjarnegara

    NASA Astrophysics Data System (ADS)

    Permata, Anggi; Juniansah, Anwar; Nurcahyati, Eka; Dimas Afrizal, Mousafi; Adnan Shafry Untoro, Muhammad; Arifatha, Na'ima; Ramadhani Yudha Adiwijaya, Raden; Farda, Nur Mohammad

    2016-11-01

    Landslide is an unpredictable natural disaster which commonly happens in highslope area. Aerial photography in small format is one of acquisition method that can reach and obtain high resolution spatial data faster than other methods, and provide data such as orthomosaic and Digital Surface Model (DSM). The study area contained landslide area in Clapar, Madukara District of Banjarnegara. Aerial photographs of landslide area provided advantage in objects visibility. Object's characters such as shape, size, and texture were clearly seen, therefore GEOBIA (Geography Object Based Image Analysis) was compatible as method for classifying land cover in study area. Dissimilar with PPA (PerPixel Analyst) method that used spectral information as base object detection, GEOBIA could use spatial elements as classification basis to establish a land cover map with better accuracy. GEOBIA method used classification hierarchy to divide post disaster land cover into three main objects: vegetation, landslide/soil, and building. Those three were required to obtain more detailed information that can be used in estimating loss caused by landslide and establishing land cover map in landslide area. Estimating loss in landslide area related to damage in Salak (Salacca zalacca) plantations. This estimation towards quantity of Salak tree that were drifted away by landslide was calculated in assumption that every tree damaged by landslide had same age and production class with other tree that weren't damaged. Loss calculation was done by approximating quantity of damaged trees in landslide area with data of trees around area that were acquired from GEOBIA classification method.

  1. Optimization of advanced Wiener estimation methods for Raman reconstruction from narrow-band measurements in the presence of fluorescence background

    PubMed Central

    Chen, Shuo; Ong, Yi Hong; Lin, Xiaoqian; Liu, Quan

    2015-01-01

    Raman spectroscopy has shown great potential in biomedical applications. However, intrinsically weak Raman signals cause slow data acquisition especially in Raman imaging. This problem can be overcome by narrow-band Raman imaging followed by spectral reconstruction. Our previous study has shown that Raman spectra free of fluorescence background can be reconstructed from narrow-band Raman measurements using traditional Wiener estimation. However, fluorescence-free Raman spectra are only available from those sophisticated Raman setups capable of fluorescence suppression. The reconstruction of Raman spectra with fluorescence background from narrow-band measurements is much more challenging due to the significant variation in fluorescence background. In this study, two advanced Wiener estimation methods, i.e. modified Wiener estimation and sequential weighted Wiener estimation, were optimized to achieve this goal. Both spontaneous Raman spectra and surface enhanced Raman spectra were evaluated. Compared with traditional Wiener estimation, two advanced methods showed significant improvement in the reconstruction of spontaneous Raman spectra. However, traditional Wiener estimation can work as effectively as the advanced methods for SERS spectra but much faster. The wise selection of these methods would enable accurate Raman reconstruction in a simple Raman setup without the function of fluorescence suppression for fast Raman imaging. PMID:26203387

  2. Assessing the Social and Environmental Costs of Institution Nitrogen Footprints

    EPA Science Inventory

    We estimate the damage costs associated with the institutional nitrogen (N) footprint and explore how this information could be used to create more sustainable institutions. Potential damages associated with the release of NOx and N2O to air and release of N to water were estima...

  3. Sulfur Dioxide and Material Damage

    ERIC Educational Resources Information Center

    Gillette, Donald G.

    1975-01-01

    This study relates sulfur dioxide levels with material damage in heavily populated or polluted areas. Estimates of loss were determined from increased maintenance and replacement costs. The data indicate a decrease in losses during the past five years probably due to decline in pollution levels established by air quality standards. (MR)

  4. 32 CFR 634.29 - Traffic accident investigation reports.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... resulted in a fatality, personal injury, or estimated damage to Government vehicles or property in excess... accident involves no personal injury. (iii) The accident involves only minor damage to the POV and the... originally categorized a hit and run and the violator is the person submitting the report. Rights advisement...

  5. External damage cost of noise emitted from motor vehicles

    DOT National Transportation Integrated Search

    1998-10-01

    With a detailed model of the cost of motor vehicle noise in the United States in 1990, it is estimated that the external damage cost of this noise could range from as little as $100 million per year to as much as $40 billion per year, although it is ...

  6. Real-time tsunami inundation forecasting and damage mapping towards enhancing tsunami disaster resiliency

    NASA Astrophysics Data System (ADS)

    Koshimura, S.; Hino, R.; Ohta, Y.; Kobayashi, H.; Musa, A.; Murashima, Y.

    2014-12-01

    With use of modern computing power and advanced sensor networks, a project is underway to establish a new system of real-time tsunami inundation forecasting, damage estimation and mapping to enhance society's resilience in the aftermath of major tsunami disaster. The system consists of fusion of real-time crustal deformation monitoring/fault model estimation by Ohta et al. (2012), high-performance real-time tsunami propagation/inundation modeling with NEC's vector supercomputer SX-ACE, damage/loss estimation models (Koshimura et al., 2013), and geo-informatics. After a major (near field) earthquake is triggered, the first response of the system is to identify the tsunami source model by applying RAPiD Algorithm (Ohta et al., 2012) to observed RTK-GPS time series at GEONET sites in Japan. As performed in the data obtained during the 2011 Tohoku event, we assume less than 10 minutes as the acquisition time of the source model. Given the tsunami source, the system moves on to running tsunami propagation and inundation model which was optimized on the vector supercomputer SX-ACE to acquire the estimation of time series of tsunami at offshore/coastal tide gauges to determine tsunami travel and arrival time, extent of inundation zone, maximum flow depth distribution. The implemented tsunami numerical model is based on the non-linear shallow-water equations discretized by finite difference method. The merged bathymetry and topography grids are prepared with 10 m resolution to better estimate the tsunami inland penetration. Given the maximum flow depth distribution, the system performs GIS analysis to determine the numbers of exposed population and structures using census data, then estimates the numbers of potential death and damaged structures by applying tsunami fragility curve (Koshimura et al., 2013). Since the tsunami source model is determined, the model is supposed to complete the estimation within 10 minutes. The results are disseminated as mapping products to responders and stakeholders, e.g. national and regional municipalities, to be utilized for their emergency/response activities. In 2014, the system is verified through the case studies of 2011 Tohoku event and potential earthquake scenarios along Nankai Trough with regard to its capability and robustness.

  7. A framework for global river flood risk assessments

    NASA Astrophysics Data System (ADS)

    Winsemius, H. C.; Van Beek, L. P. H.; Jongman, B.; Ward, P. J.; Bouwman, A.

    2013-05-01

    There is an increasing need for strategic global assessments of flood risks in current and future conditions. In this paper, we propose a framework for global flood risk assessment for river floods, which can be applied in current conditions, as well as in future conditions due to climate and socio-economic changes. The framework's goal is to establish flood hazard and impact estimates at a high enough resolution to allow for their combination into a risk estimate, which can be used for strategic global flood risk assessments. The framework estimates hazard at a resolution of ~ 1 km2 using global forcing datasets of the current (or in scenario mode, future) climate, a global hydrological model, a global flood-routing model, and more importantly, an inundation downscaling routine. The second component of the framework combines hazard with flood impact models at the same resolution (e.g. damage, affected GDP, and affected population) to establish indicators for flood risk (e.g. annual expected damage, affected GDP, and affected population). The framework has been applied using the global hydrological model PCR-GLOBWB, which includes an optional global flood routing model DynRout, combined with scenarios from the Integrated Model to Assess the Global Environment (IMAGE). We performed downscaling of the hazard probability distributions to 1 km2 resolution with a new downscaling algorithm, applied on Bangladesh as a first case study application area. We demonstrate the risk assessment approach in Bangladesh based on GDP per capita data, population, and land use maps for 2010 and 2050. Validation of the hazard estimates has been performed using the Dartmouth Flood Observatory database. This was done by comparing a high return period flood with the maximum observed extent, as well as by comparing a time series of a single event with Dartmouth imagery of the event. Validation of modelled damage estimates was performed using observed damage estimates from the EM-DAT database and World Bank sources. We discuss and show sensitivities of the estimated risks with regard to the use of different climate input sets, decisions made in the downscaling algorithm, and different approaches to establish impact models.

  8. Structural damage diagnostics via wave propagation-based filtering techniques

    NASA Astrophysics Data System (ADS)

    Ayers, James T., III

    Structural health monitoring (SHM) of aerospace components is a rapidly emerging field due in part to commercial and military transport vehicles remaining in operation beyond their designed life cycles. Damage detection strategies are sought that provide real-time information of the structure's integrity. One approach that has shown promise to accurately identify and quantify structural defects is based on guided ultrasonic wave (GUW) inspections, where low amplitude attenuation properties allow for long range and large specimen evaluation. One drawback to GUWs is that they exhibit a complex multi-modal response, such that each frequency corresponds to at least two excited modes, and thus intelligent signal processing is required for even the simplest of structures. In addition, GUWs are dispersive, whereby the wave velocity is a function of frequency, and the shape of the wave packet changes over the spatial domain, requiring sophisticated detection algorithms. Moreover, existing damage quantification measures are typically formulated as a comparison of the damaged to undamaged response, which has proven to be highly sensitive to changes in environment, and therefore often unreliable. As a response to these challenges inherent to GUW inspections, this research develops techniques to locate and estimate the severity of the damage. Specifically, a phase gradient based localization algorithm is introduced to identify the defect position independent of excitation frequency and damage size. Mode separation through the filtering technique is central in isolating and extracting single mode components, such as reflected, converted, and transmitted modes that may arise from the incident wave impacting a damage. Spatially-integrated single and multiple component mode coefficients are also formulated with the intent to better characterize wave reflections and conversions and to increase the signal to noise ratios. The techniques are applied to damaged isotropic finite element plate models and experimental data obtained from Scanning Laser Doppler Vibrometry tests. Numerical and experimental parametric studies are conducted, and the current strengths and weaknesses of the proposed approaches are discussed. In particular, limitations to the damage profiling characterization are shown for low ultrasonic frequency regimes, whereas the multiple component mode conversion coefficients provide excellent noise mitigation. Multiple component estimation relies on an experimental technique developed for the estimation of Lamb wave polarization using a 1D Laser Vibrometer. Lastly, suggestions are made to apply the techniques to more structurally complex geometries.

  9. [IR spectral-analysis-based range estimation for an object with small temperature difference from background].

    PubMed

    Fu, Xiao-Ning; Wang, Jie; Yang, Lin

    2013-01-01

    It is a typical passive ranging technology that estimation of distance of an object is based on transmission characteristic of infrared radiation, it is also a hotspot in electro-optic countermeasures. Because of avoiding transmitting energy in the detection, this ranging technology will significantly enhance the penetration capability and infrared conceal capability of the missiles or unmanned aerial vehicles. With the current situation in existing passive ranging system, for overcoming the shortage in ranging an oncoming target object with small temperature difference from background, an improved distance estimation scheme was proposed. This article begins with introducing the concept of signal transfer function, makes clear the working curve of current algorithm, and points out that the estimated distance is not unique due to inherent nonlinearity of the working curve. A new distance calculation algorithm was obtained through nonlinear correction technique. It is a ranging formula by using sensing information at 3-5 and 8-12 microm combined with background temperature and field meteorological conditions. The authors' study has shown that the ranging error could be mainly kept around the level of 10% under the condition of the target and background apparent temperature difference equal to +/- 5 K, and the error in estimating background temperature is no more than +/- 15 K.

  10. Flood area and damage estimation in Zhejiang, China.

    PubMed

    Liu, Renyi; Liu, Nan

    2002-09-01

    A GIS-based method to estimate flood area and damage is presented in this paper, which is oriented to developing countries like China, where labor is readily available for GIS data collecting, and tools such as, HEC-GeoRAS might not be readily available. At present local authorities in developing countries are often not predisposed to pay for commercial GIS platforms. To calculate flood area, two cases, non-source flood and source flood, are distinguished and a seed-spread algorithm suitable for source-flooding is described. The flood damage estimation is calculated in raster format by overlaying the flood area range with thematic maps and relating this to other socioeconomic data. Several measures used to improve the geometric accuracy and computing efficiency are presented. The management issues related to the application of this method, including the cost-effectiveness of approximate method in practice and supplementing two technical lines (self-programming and adopting commercial GIS software) to each other, are also discussed. The applications show that this approach has practical significance to flood fighting and control in developing countries like China.

  11. A real time neural net estimator of fatigue life

    NASA Technical Reports Server (NTRS)

    Troudet, T.; Merrill, W.

    1990-01-01

    A neural network architecture is proposed to estimate, in real-time, the fatigue life of mechanical components, as part of the intelligent Control System for Reusable Rocket Engines. Arbitrary component loading values were used as input to train a two hidden-layer feedforward neural net to estimate component fatigue damage. The ability of the net to learn, based on a local strain approach, the mapping between load sequence and fatigue damage has been demonstrated for a uniaxial specimen. Because of its demonstrated performance, the neural computation may be extended to complex cases where the loads are biaxial or triaxial, and the geometry of the component is complex (e.g., turbopumps blades). The generality of the approach is such that load/damage mappings can be directly extracted from experimental data without requiring any knowledge of the stress/strain profile of the component. In addition, the parallel network architecture allows real-time life calculations even for high-frequency vibrations. Owing to its distributed nature, the neural implementation will be robust and reliable, enabling its use in hostile environments such as rocket engines.

  12. A comparison of socio-economic loss analysis from the 2013 Haiyan Typhoon and Bohol Earthquake events in the Philippines in near real-time

    NASA Astrophysics Data System (ADS)

    Daniell, James; Mühr, Bernhard; Kunz-Plapp, Tina; Brink, Susan A.; Kunz, Michael; Khazai, Bijan; Wenzel, Friedemann

    2014-05-01

    In the aftermath of a disaster, the extent of the socioeconomic loss (fatalities, homelessness and economic losses) is often not known and it may take days before a reasonable estimate is known. Using the technique of socio-economic fragility functions developed (Daniell, 2014) using a regression of socio-economic indicators through time against historical empirical loss vs. intensity data, a first estimate can be established. With more information from the region as the disaster unfolds, a more detailed estimate can be provided via a calibration of the initial loss estimate parameters. In 2013, two main disasters hit the Philippines; the Bohol earthquake in October and the Haiyan typhoon in November. Although both disasters were contrasting and hit different regions, the same generalised methodology was used for initial rapid estimates and then the updating of the disaster loss estimate through time. The CEDIM Forensic Disaster Analysis Group of KIT and GFZ produced 6 reports for Bohol and 2 reports for Haiyan detailing various aspects of the disasters from the losses to building damage, the socioeconomic profile and also the social networking and disaster response. This study focusses on the loss analysis undertaken. The following technique was used:- 1. A regression of historical earthquake and typhoon losses for the Philippines was examined using the CATDAT Damaging Earthquakes Database, and various Philippines databases respectively. 2. The historical intensity impact of the examined events were placed in a GIS environment in order to allow correlation with the population and capital stock database from 1900-2013 to create a loss function. The modified human development index from 1900-2013 was also used to also calibrate events through time. 3. The earthquake intensity and the wind speed intensity was used from the 2013 events as well as the 2013 capital stock and population in order to calculate the number of fatalities (except in Haiyan), homeless and economic losses. 4. After the initial estimate, damage patterns were examined and the loss estimates calibrated. The economic loss estimates of 9.5 billion USD capital stock and 4.1 billion USD GDP costs and the estimate of 2.1 million long term homeless from the Typhoon Haiyan event from the initial model proved very accurate with around the same values coming from reports around a month after the event. For the Bohol earthquake, the economic loss estimate was reasonable (around 100 million USD), however, the number of fatalities was slightly underestimated given the intensity field being underestimated and due to the number of landslide and other deaths (heart attacks etc.) in the first day. As the damage estimates were reported on post-disaster over the next days, the fatality function was calibrated and produced results closer to 200 deaths. Such parsimonious modelling in the aftermath of a disaster and socioeconomic profiling of the disaster area can prove useful to relief agencies and governments as well as those on the ground giving a first estimate of the extent of the damage and the models will as such continue to be developed in the course of FDA. Daniell J.E. (2014) The development of socio-economic fragility functions for use in worldwide rapid earthquake loss estimation procedures, Ph.D. Thesis (in publishing), Karlsruhe Institute of Technology, Karlsruhe, Germany.

  13. The Future of the South Atlantic Anomaly and Implications for Radiation Damage in Space

    NASA Technical Reports Server (NTRS)

    Heirtzler, J. R.; Smith, David E. (Technical Monitor)

    2000-01-01

    South Atlantic Anomaly of the geomagnetic field plays a dominant role in where radiation damage occurs in near Earth orbits. The historic and recent variations of the geomagnetic field in the South Atlantic are used to estimate the extent of the South Atlantic Anomaly until the year 2000. This projection indicates that radiation damage to spacecraft and humans in space will greatly increase and cover a much larger geographic area than present.

  14. DNA-damage response associated with occupational exposure, age and chronic inflammation in workers in the automotive industry.

    PubMed

    Savina, Natalya V; Smal, Marharyta P; Kuzhir, Tatyana D; Ershova-Pavlova, Alla A; Goncharova, Roza I

    2012-10-09

    The evaluation of genome integrity in populations occupationally exposed to combine industrial factors is of medical importance. In the present study, the DNA-damage response was estimated by means of the alkaline comet assay in a sizeable cohort of volunteers recruited among workers in the automotive industry. For this purpose, freshly collected lymphocytes were treated with hydrogen peroxide (100μM, 1min, 4°C) in vitro, and the levels of basal and H(2)O(2)-induced DNA damage, and the kinetics and efficiency of DNA repair were measured during a 180-min interval after exposure. The parameters studied in the total cohort of workers were in a range of values prescribed for healthy adult residents of Belarus. Based on the 95th percentiles, individuals possessing enhanced cellular sensitivity to DNA damage were present in different groups, but the frequency was significantly higher among elderly persons and among individuals with chronic inflammatory diseases. The results indicate that the inter-individual variations in DNA-damage response should be taken into account to estimate adequately the environmental genotoxic effects and to identify individuals with an enhanced DNA-damage response due to the influence of some external factors or intrinsic properties of the organism. Underling mechanisms need to be further explored. © 2012 Elsevier B.V. All rights reserved.

  15. A real time neural net estimator of fatigue life

    NASA Technical Reports Server (NTRS)

    Troudet, T.; Merrill, W.

    1990-01-01

    A neural net architecture is proposed to estimate, in real-time, the fatigue life of mechanical components, as part of the Intelligent Control System for Reusable Rocket Engines. Arbitrary component loading values were used as input to train a two hidden-layer feedforward neural net to estimate component fatigue damage. The ability of the net to learn, based on a local strain approach, the mapping between load sequence and fatigue damage has been demonstrated for a uniaxial specimen. Because of its demonstrated performance, the neural computation may be extended to complex cases where the loads are biaxial or triaxial, and the geometry of the component is complex (e.g., turbopump blades). The generality of the approach is such that load/damage mappings can be directly extracted from experimental data without requiring any knowledge of the stress/strain profile of the component. In addition, the parallel network architecture allows real-time life calculations even for high frequency vibrations. Owing to its distributed nature, the neural implementation will be robust and reliable, enabling its use in hostile environments such as rocket engines. This neural net estimator of fatigue life is seen as the enabling technology to achieve component life prognosis, and therefore would be an important part of life extending control for reusable rocket engines.

  16. Uncovering the 2010 Haiti earthquake death toll

    NASA Astrophysics Data System (ADS)

    Daniell, J. E.; Khazai, B.; Wenzel, F.

    2013-05-01

    Casualties are estimated for the 12 January 2010 earthquake in Haiti using various reports calibrated by observed building damage states from satellite imagery and reconnaissance reports on the ground. By investigating various damage reports, casualty estimates and burial figures, for a one year period from 12 January 2010 until 12 January 2011, there is also strong evidence that the official government figures of 316 000 total dead and missing, reported to have been caused by the earthquake, are significantly overestimated. The authors have examined damage and casualties report to arrive at their estimation that the median death toll is less than half of this value (±137 000). The authors show through a study of historical earthquake death tolls, that overestimates of earthquake death tolls occur in many cases, and is not unique to Haiti. As death toll is one of the key elements for determining the amount of aid and reconstruction funds that will be mobilized, scientific means to estimate death tolls should be applied. Studies of international aid in recent natural disasters reveal that large distributions of aid which do not match the respective needs may cause oversupply of help, aggravate corruption and social disruption rather than reduce them, and lead to distrust within the donor community.

  17. Chemical Plume Detection with an Iterative Background Estimation Technique

    DTIC Science & Technology

    2016-05-17

    schemes because of contamination of background statistics by the plume. To mitigate the effects of plume contamination , a first pass of the detector...can be used to create a background mask. However, large diffuse plumes are typically not removed by a single pass. Instead, contamination can be...is estimated using plume-pixels, the covariance matrix is contaminated and detection performance may be significantly reduced. To avoid Further author

  18. Systems approach to the study of brain damage in the very preterm newborn

    PubMed Central

    Leviton, Alan; Gressens, Pierre; Wolkenhauer, Olaf; Dammann, Olaf

    2015-01-01

    Background: A systems approach to the study of brain damage in very preterm newborns has been lacking. Methods: In this perspective piece, we offer encephalopathy of prematurity as an example of the complexity and interrelatedness of brain-damaging molecular processes that can be initiated inflammatory phenomena. Results: Using three transcription factors, nuclear factor-kappa B (NF-κB), Notch-1, and nuclear factor erythroid 2 related factor 2 (NRF2), we show the inter-connectedness of signaling pathways activated by some antecedents of encephalopathy of prematurity. Conclusions: We hope that as biomarkers of exposures and processes leading to brain damage in the most immature newborns become more readily available, those who apply a systems approach to the study of neuroscience can be persuaded to study the pathogenesis of brain disorders in the very preterm newborn. PMID:25926780

  19. An Empirical Method to Assess the Seismic Vulnerability of Existing Buildings Using the HVSR Technique

    NASA Astrophysics Data System (ADS)

    Mucciarelli, M.; Contri, P.; Monachesi, G.; Calvano, G.; Gallipoli, M.

    - The seismic vulnerability of existing buildings is usually estimated according to procedures based on checklists of main structural features. The relationship with damage is then assessed using experience from past events. An approach used in seismology for the evaluation of site amplification, based on horizontal-to-vertical ratio of weak motion and microtremors, has been applied to the structural field. This methodology provides an alternative, promising tool towards a quick and reliable estimate of seismic vulnerability. The advantages are:• The measurements are quick, simple and stable. They are non-invasive and do not affect at all, even temporarily, the functions housed in the buildings studied.• The site effect and the soil structure interaction are explicitly accounted for in the vulnerability estimate, when they are excluded in the traditional approaches.• The relationship with damage is established using meaningful physical parameters related to the construction technology, instead of adimensional, normalised indexes. The procedure has been applied to several case histories of buildings damaged in the recent Umbria-Marche earthquake which occurred in Italy in 1997. The same model has been applied to different structures (brick/stone masonry and infilled r.c. frames), on different geological conditions and under very different seismic loads. Using this combined site/building approach, it was possible to explain very sharp variations in the damage pattern.

  20. FEMA Asteroid Impact Tabletop Exercise Simulations

    DOE PAGES

    Boslough, Mark; Jennings, Barbara; Carvey, Brad; ...

    2015-05-19

    We describe the computational simulations and damage assessments that we provided in support of a tabletop exercise (TTX) at the request of NASA's Near-Earth Objects Program Office. The overall purpose of the exercise was to assess leadership reactions, information requirements, and emergency management responses to a hypothetical asteroid impact with Earth. The scripted exercise consisted of discovery, tracking, and characterization of a hypothetical asteroid; inclusive of mission planning, mitigation, response, impact to population, infrastructure and GDP, and explicit quantification of uncertainty. Participants at the meeting included representatives of NASA, Department of Defense, Department of State, Department of Homeland Security/Federal Emergencymore » Management Agency (FEMA), and the White House. The exercise took place at FEMA headquarters. Sandia's role was to assist the Jet Propulsion Laboratory (JPL) in developing the impact scenario, to predict the physical effects of the impact, and to forecast the infrastructure and economic losses. We ran simulations using Sandia's CTH hydrocode to estimate physical effects on the ground, and to produce contour maps indicating damage assessments that could be used as input for the infrastructure and economic models. We used the FASTMap tool to provide estimates of infrastructure damage over the affected area, and the REAcct tool to estimate the potential economic severity expressed as changes to GDP (by nation, region, or sector) due to damage and short-term business interruptions.« less

  1. FEMA Asteroid Impact Tabletop Exercise Simulations

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Boslough, Mark; Jennings, Barbara; Carvey, Brad

    We describe the computational simulations and damage assessments that we provided in support of a tabletop exercise (TTX) at the request of NASA's Near-Earth Objects Program Office. The overall purpose of the exercise was to assess leadership reactions, information requirements, and emergency management responses to a hypothetical asteroid impact with Earth. The scripted exercise consisted of discovery, tracking, and characterization of a hypothetical asteroid; inclusive of mission planning, mitigation, response, impact to population, infrastructure and GDP, and explicit quantification of uncertainty. Participants at the meeting included representatives of NASA, Department of Defense, Department of State, Department of Homeland Security/Federal Emergencymore » Management Agency (FEMA), and the White House. The exercise took place at FEMA headquarters. Sandia's role was to assist the Jet Propulsion Laboratory (JPL) in developing the impact scenario, to predict the physical effects of the impact, and to forecast the infrastructure and economic losses. We ran simulations using Sandia's CTH hydrocode to estimate physical effects on the ground, and to produce contour maps indicating damage assessments that could be used as input for the infrastructure and economic models. We used the FASTMap tool to provide estimates of infrastructure damage over the affected area, and the REAcct tool to estimate the potential economic severity expressed as changes to GDP (by nation, region, or sector) due to damage and short-term business interruptions.« less

  2. The impacts of tropical cyclones on the net carbon balance of eastern US forests (1851-2000)

    NASA Astrophysics Data System (ADS)

    Fisk, J. P.; Hurtt, G. C.; Chambers, J. Q.; Zeng, H.; Dolan, K. A.; Negrón-Juárez, R. I.

    2013-12-01

    In temperate forests of the eastern US, tropical cyclones are a principal agent of catastrophic wind damage, with dramatic impacts on the structure and functioning of forests. Substantial progress has been made to quantify forest damage and resulting gross carbon emissions from tropical cyclones. However, the net effect of storms on the carbon balance of forests depends not only on the biomass lost in single events, but also on the uptake during recovery from a mosaic of past events. This study estimates the net impacts of tropical cyclones on the carbon balance of US forests over the period 1851-2000. To track both disturbance and recovery and to isolate the effects of storms, a modeling framework is used combining gridded historical estimates of mortality and damage with a mechanistic model using an ensemble approach. The net effect of tropical cyclones on the carbon balance is shown to depend strongly on the spatial and temporal scales of analysis. On average, tropical cyclones contribute a net carbon source over latter half of the 19th century. However, throughout much of the 20th century a regional carbon sink is estimated resulting from periods of forest recovery exceeding damage. The large-scale net annual flux resulting from tropical cyclones varies by up to 50 Tg C yr-1, an amount equivalent to 17%-36% of the US forest carbon sink.

  3. Economic Impacts of Infrastructure Damages on Industrial Sector

    NASA Astrophysics Data System (ADS)

    Kajitani, Yoshio

    This paper proposes a basic model for evaluating economic impacts on industrial sectors under the conditions that multiple infrastructures are simultaneously damaged during the earthquake disasters. Especially, focusing on the available economic data developed in the smallest spatial scale in Japan (small area statistics), economic loss estimation model based on the small area statistics and its applicability are investigated on. In the detail, a loss estimation framework, utilizing survey results on firms' activities under electricity, water and gas disruptions, and route choice models in Transportation Engineering, are applied to the case of 2004 Mid-Niigata Earthquake.

  4. Validation of Satellite-based Rainfall Estimates for Severe Storms (Hurricanes & Tornados)

    NASA Astrophysics Data System (ADS)

    Nourozi, N.; Mahani, S.; Khanbilvardi, R.

    2005-12-01

    Severe storms such as hurricanes and tornadoes cause devastating damages, almost every year, over a large section of the United States. More accurate forecasting intensity and track of a heavy storm can help to reduce if not to prevent its damages to lives, infrastructure, and economy. Estimating accurate high resolution quantitative precipitation (QPE) from a hurricane, required to improve the forecasting and warning capabilities, is still a challenging problem because of physical characteristics of the hurricane even when it is still over the ocean. Satellite imagery seems to be a valuable source of information for estimating and forecasting heavy precipitation and also flash floods, particularly for over the oceans where the traditional ground-based gauge and radar sources cannot provide any information. To improve the capability of a rainfall retrieval algorithm for estimating QPE of severe storms, its product is evaluated in this study. High (hourly 4km x 4km) resolutions satellite infrared-based rainfall products, from the NESDIS Hydro-Estimator (HE) and also PERSIANN (Precipitation Estimation from Remotely Sensed Information using an Artificial Neural Networks) algorithms, have been tested against NEXRAD stage-IV and rain gauge observations in this project. Three strong hurricanes: Charley (category 4), Jeanne (category 3), and Ivan (category 3) that caused devastating damages over Florida in the summer 2004, have been considered to be investigated. Preliminary results demonstrate that HE tends to underestimate rain rates when NEXRAD shows heavy storm (rain rates greater than 25 mm/hr) and to overestimate when NEXRAD gives low rainfall amounts, but PERSIANN tends to underestimate rain rates, in general.

  5. [Spinal cord injury due to penetrating missiles].

    PubMed

    Ohry, Avi

    2003-10-01

    Gunshot wound of the spine is a major cause of spinal cord injury among US civilian population, members of the military armed conflict personnel, or civilians injured in terrorists attacks. The bullet fragments cause damage to the spinal cord even without penetrating the spinal canal. Concussive effects, heat, fractures or vascular injury may cause the neurological damage. Unfortunately, bullet or shrapnel removal or laminectomy do not change the prognosis. In this article we review the historical background, the Israeli experience, ballistic-forensic considerations, complications, treatment and prognosis.

  6. Glomerular Hyperfiltration in Adult Sickle Cell Anemia: A Frequent Hemolysis Associated Feature

    PubMed Central

    Stankovic, Katia; Levy, Pierre; Avellino, Virginie; Tharaux, Pierre-Louis; Letavernier, Emmanuel; Grateau, Gilles; Baud, Laurent; Girot, Robert; Lionnet, François

    2010-01-01

    Background and objectives: Sickle cell anemia-associated nephropathy is a growing matter of concern because renal failure affects most aging sickle cell anemia patients. Glomerular damage is a common feature revealed by a microalbuminuria or a macroalbuminuria. Although glomerular hyperfiltration has been described for decades in this population, its prevalence in young adults is unknown. Design, setting, participants, & measurements: To address this issue, as well as the clinical and biologic correlates of hyperfiltration, a single-center, cross-sectional study of 280 homozygous SS disease patients was performed. Results: The prevalence of hyperfiltration assessed by Modification of Diet in Renal Disease estimated GFR was 51%. Among patients with hyperfiltration, 49% had hyperfiltration alone, whereas 36% and 15% had an associated microalbuminuria or macroalbuminuria, respectively. Estimated GFR sensitivity and specificity for hyperfiltration were 94% and 63%, respectively, in a selected subgroup of 48 patients (measured GFR was assessed by urinary 51Cr EDTA clearance). In patients with no albuminuria, hyperfiltration status was significantly associated with a young age (years), the absence of alpha thalassemia, a lower hemoglobin level (g/dl), and a lower fetal hemoglobin. The role of chronic hemolysis was further strengthened by multivariate analysis showing a correlation between estimated GFR and a low plasma fetal hemoglobin level, a young age, and a high reticulocyte count (r2 = 0.54). Conclusions: Together, the data suggest that the pathophysiology of hyperfiltration would rather be attributable to the hemolysis-associated vasculopathy rather than a viscosity-vaso-occlusive process. PMID:20185605

  7. Thermal anomaly before earthquake and damage assessment using remote sensing data for 2014 Yutian earthquake

    NASA Astrophysics Data System (ADS)

    Zhang, Yanmei; Huang, Haiying; Jiang, Zaisen; Fang, Ying; Cheng, Xiao

    2014-12-01

    Thermal anomaly appears to be a significant precursor of some strong earthquakes. In this study, time series of MODIS Land Surface Temperature (LST) products from 2001 to 2014 are processed and analyzed to locate possible anomalies prior to the Yutian earthquake (12 February 2014, Xinjiang, CHINA). In order to reduce the seasonal or annual effects from the LST variations, also to avoid the rainy and cloudy weather in this area, a background mean of ten-day nighttime LST are derived using averaged MOD11A2 products from 2001 to 2012. Then the ten-day LST data from Jan 2014 to FebJanuary 2014 were differenced using the above background. Abnormal LST increase before the earthquake is quite obvious from the differential images, indicating that this method is useful in such area with high mountains and wide-area deserts. Also, in order to assess the damage to infrastructure, China's latest civilian high-resolution remote sensing satellite - GF-1 remote sensed data are applied to the affected counties in this area. The damaged infrastructures and ground surface could be easily interpreted in the fused pan-chromatic and multi-spectral images integrating both texture and spectral information.

  8. Hurricane Harvey Building Damage Assessment Using UAV Data

    NASA Astrophysics Data System (ADS)

    Yeom, J.; Jung, J.; Chang, A.; Choi, I.

    2017-12-01

    Hurricane Harvey which was extremely destructive major hurricane struck southern Texas, U.S.A on August 25, causing catastrophic flooding and storm damages. We visited Rockport suffered severe building destruction and conducted UAV (Unmanned Aerial Vehicle) surveying for building damage assessment. UAV provides very high resolution images compared with traditional remote sensing data. In addition, prompt and cost-effective damage assessment can be performed regardless of several limitations in other remote sensing platforms such as revisit interval of satellite platforms, complicated flight plan in aerial surveying, and cloud amounts. In this study, UAV flight and GPS surveying were conducted two weeks after hurricane damage to generate an orthomosaic image and a DEM (Digital Elevation Model). 3D region growing scheme has been proposed to quantitatively estimate building damages considering building debris' elevation change and spectral difference. The result showed that the proposed method can be used for high definition building damage assessment in a time- and cost-effective way.

  9. Dam-Break Flooding and Structural Damage in a Residential Neighborhood: Performance of a coupled hydrodynamic-damage model

    NASA Astrophysics Data System (ADS)

    Sanders, B. F.; Gallegos, H. A.; Schubert, J. E.

    2011-12-01

    The Baldwin Hills dam-break flood and associated structural damage is investigated in this study. The flood caused high velocity flows exceeding 5 m/s which destroyed 41 wood-framed residential structures, 16 of which were completed washed out. Damage is predicted by coupling a calibrated hydrodynamic flood model based on the shallow-water equations to structural damage models. The hydrodynamic and damage models are two-way coupled so building failure is predicted upon exceedance of a hydraulic intensity parameter, which in turn triggers a localized reduction in flow resistance which affects flood intensity predictions. Several established damage models and damage correlations reported in the literature are tested to evaluate the predictive skill for two damage states defined by destruction (Level 2) and washout (Level 3). Results show that high-velocity structural damage can be predicted with a remarkable level of skill using established damage models, but only with two-way coupling of the hydrodynamic and damage models. In contrast, when structural failure predictions have no influence on flow predictions, there is a significant reduction in predictive skill. Force-based damage models compare well with a subset of the damage models which were devised for similar types of structures. Implications for emergency planning and preparedness as well as monetary damage estimation are discussed.

  10. Assessment of mean annual flood damage using simple hydraulic modeling and Monte Carlo simulation

    NASA Astrophysics Data System (ADS)

    Oubennaceur, K.; Agili, H.; Chokmani, K.; Poulin, J.; Marceau, P.

    2016-12-01

    Floods are the most frequent and the most damaging natural disaster in Canada. The issue of assessing and managing the risk related to this disaster has become increasingly crucial for both local and national authorities. Brigham, a municipality located in southern Quebec Province, is one of the heavily affected regions by this disaster because of frequent overflows of the Yamaska River reaching two to three times per year. Since Irene Hurricane which struck the region in 2011, causing considerable socio-economic damage, the implementation of mitigation measures has become a major priority for this municipality. To do this, a preliminary study to evaluate the risk to which this region is exposed is essential. Conventionally, approaches only based on the characterization of the hazard (e.g. floodplains extensive, flood depth) are generally adopted to study the risk of flooding. In order to improve the knowledge of this risk, a Monte Carlo simulation approach combining information on the hazard with vulnerability-related aspects has been developed. This approach integrates three main components: (1) hydrologic modelling aiming to establish a probability-discharge function which associate each measured discharge to its probability of occurrence (2) hydraulic modeling that aims to establish the relationship between the discharge and the water stage at each building (3) damage study that aims to assess the buildings damage using damage functions. The damage is estimated according to the water depth defined as the difference between the water level and the elevation of the building's first floor. The application of the proposed approach allows estimating the annual average cost of damage caused by floods on buildings. The obtained results will be useful for authorities to support their decisions on risk management and prevention against this disaster.

  11. Potential effects of environmental contaminants on P450 aromatase activity and DNA damage in swallows from the Rio Grande and Somerville, Texas

    USGS Publications Warehouse

    Sitzlar, M.A.; Mora, M.A.; Fleming, J.G.W.; Bazer, F.W.; Bickham, J.W.; Matson, C.W.

    2009-01-01

    Cliff swallows (Petrochelidon pyrrhonota) and cave swallows (P. fulva) were sampled during the breeding season at several locations in the Rio Grande, Texas, to evaluate the potential effects of environmental contaminants on P450 aromatase activity in brain and gonads and DNA damage in blood cells. The tritiated water-release aromatase assay was used to measure aromatase activity and flow cytometry was used to measure DNA damage in nucleated blood cells. There were no significant differences in brain and gonadal aromatase activities or in estimates of DNA damage (HPCV values) among cave swallow colonies from the Lower Rio Grande Valley (LRGV) and Somerville. However, both brain and gonadal aromatase activities were significantly higher (P < 0.05) in male cliff swallows from Laredo than in those from Somerville. Also, DNA damage estimates were significantly higher (P < 0.05) in cliff swallows (males and females combined) from Laredo than in those from Somerville. Contaminants of current high use in the LRGV, such as atrazine, and some of the highly persistent organochlorines, such as toxaphene and DDE, could be potentially associated with modulation of aromatase activity in avian tissues. Previous studies have indicated possible DNA damage in cliff swallows. We did not observe any differences in aromatase activity or DNA damage in cave swallows that could be associated with contaminant exposure. Also, the differences in aromatase activity and DNA damage between male cliff swallows from Laredo and Somerville could not be explained by contaminants measured at each site in previous studies. Our study provides baseline information on brain and gonadal aromatase activity in swallows that could be useful in future studies. ?? 2008 Springer Science+Business Media, LLC.

  12. Individual variations in the correlation between erythemal threshold, UV-induced DNA damage and sun-burn cell formation.

    PubMed

    Heenen, M; Giacomoni, P U; Golstein, P

    2001-10-01

    A linear correlation between erythema intensity and DNA damage upon exposure to UV has not been firmly established. Many of the deleterious effects of UV exposure do occur after exposure to suberythemal doses. After DNA damage, cells undergo DNA repair. It is commonly accepted that when the burden of damage is beyond the repair capacities, the cell undergoes programmed cell death or apoptosis. The aim of this study is to quantify the amount of UV-induced DNA damage (estimated via the measurement of DNA repair or unscheduled DNA synthesis or UDS) and cellular damage (estimated via the determination of the density of sunburn cells or SBC). If DNA damage and erythema are correlated, similar intensity of UDS and similar density of SBC should be found in volunteers irradiated with a UV dose equal to two minimal erythema doses (MED). Our results show that in 15 different individuals the same relative dose (2 MEDs) provokes UDS values, which vary within a factor of 4. An even larger variability affects SBC counts after the same relative dose. When DNA damage or SBC are plotted versus the absolute dose (i.e. the dose expressed in J/m(2)), there is a rough correlation (with several exceptions) between dose and extent of UDS and SBC counts. It seems possible to divide the volunteers into two subpopulations with different susceptibilities to UV damage. It is well known that UDS and SBC measurements are often affected by large experimental indeterminacy, yet, the analysis of our results makes it plausible to suggest that for the triggering of erythema, a common threshold value for DNA damage or for SBC count are not to be found. In conclusion, the erythema response seems to be loosely correlated with DNA damage. This suggests that the protection offered by the sunscreens against DNA damage, the molecular basis of UV-induced mutagenesis, might not be related to the sun protection factor (SPF) indicated on the label of sunscreens, which is evaluated using the erythema as an endpoint.

  13. Flood Damage Assessment in Pearl River Delta Rural Area Application in Huashan Town, Huadu District,Guanghzou during the 2017 5.7 Heavy Rain Storm

    NASA Astrophysics Data System (ADS)

    Wang, X.

    2017-12-01

    The Pearl River Delta (PRD) in China, the summer rain storm occurs frequently, the flood damage is very serious. Damage assessment is the basis of scientific decision-making in disaster mitigation. All approaches of flood damage analysis contain uncertainties due to the inaccuracies and generalisations used, the lack of data aggravates this problem, making methods very rough. This study presents a detailed flood damage assessment framework in Pearl River Delta rural area, using 2017 "5.7" heavy rain storm event to simulate the process and estimate the flood loss in resident building and property, agriculture production. The framework integrates four modules,1) utilize the remote sensing and statistical yearbook and so on to construct the disaster bearing bodies GIS database; 2) using hydraulics model to simulate the flood extent and depth spatial distribution;3)through field investigation to obtain the flood loss data for all kinds of hazard-affected body, using statistical analysis method to get the damage curves;4)Integrate flood scenarios, disaster bearing bodies GIS database and damage curves to calculate the flood loss estimation value. Using this methodology, in the 2017 "5.7" heavy rain storm event, Huashan Town flood damage loss is underestimate compared with the government report, because of not considering the damage of water conservancy facilities. But the disaster loss value on the spatial distribution is consistent with actual situation. In terms of aggregated values in the whole town, the model is capable of obtaining figures that are within the same order of magnitude. This study produce a flood damage assessment framework taking into account the regional characteristics of PRD rural area, provide a template for future practice. This study only considers the current impacts, the framework should be improved by taking into account socio-economic and climatic changes, as well as implementing adaptation measures to be applied to assess the potential future damages. Key words: Heavy rain storm; flood; damage assessment; Pearl River Delta; rural area

  14. Simulation of PEP-II Accelerator Backgrounds Using TURTLE

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Barlow, R.J.; Fieguth, T.; /SLAC

    2006-02-15

    We present studies of accelerator-induced backgrounds in the BaBar detector at the SLAC B-Factory, carried out using LPTURTLE, a modified version of the DECAY TURTLE simulation package. Lost-particle backgrounds in PEP-II are dominated by a combination of beam-gas bremstrahlung, beam-gas Coulomb scattering, radiative-Bhabha events and beam-beam blow-up. The radiation damage and detector occupancy caused by the associated electromagnetic shower debris can limit the usable luminosity. In order to understand and mitigate such backgrounds, we have performed a full program of beam-gas and luminosity-background simulations, that include the effects of the detector solenoidal field, detailed modeling of limiting apertures in bothmore » collider rings, and optimization of the betatron collimation scheme in the presence of large transverse tails.« less

  15. Restructuring, Restoring and Rebuilding

    ERIC Educational Resources Information Center

    Hamilton, Kendra

    2006-01-01

    The 27 institutions damaged by hurricanes Katrina or Rita--there were 14 in Mississippi, 12 in Louisiana and one in Alabama--estimate their combined physical damages at $1.4 billion. But rather than providing aid, the Louisiana Legislature was forced to call for $77 million in cuts in November, leading to a wrenching gut-check on many campuses.…

  16. Workshop: Improving the Assessment and Valuation of Climate Change Impacts for Policy and Regulatory Analysis: Modeling Climate Change Impacts and Associated Economic Damages (2011 - part 2)

    EPA Pesticide Factsheets

    The purpose of this workshop Improving the Assessment and Valuation of Climate Change Impacts for Policy and Regulatory Analysis. focused on conceptual and methodological issues - estimating impacts and valuing damages on a sectoral basis.

  17. Assessing the cost of an invasive forest pathogen; A case study with oak wilt

    Treesearch

    Robert G. Haight; Frances R. Homans; Tetsuya Horie; Shefali V. Mehta; David J. Smith; Robert C. Venette

    2011-01-01

    Economic assessment of damage caused by invasive alien species provides useful information to consider when determining whether management programs should be established, modified, or discontinued. We estimate the baseline economic damage from an invasive alien pathogen, Ceratocystis fagacearum, a fungus that causes oak wilt, which is a significant...

  18. Silvicultural lessons from the December 2000 ice storms

    Treesearch

    Don C. Bragg; Michael G. Shelton; Eric Heitzman

    2002-01-01

    In December of 2000, two destructive ice storms covered Arkansas, affecing 40% of the state's forestlands. Damage estimates ran into the hundreds of millions of dollars, with much of the loss occuring in loblolly pine () plantations. A study was initiated in south-central Arkansas to track the recovery of damaged trees on these...

  19. Developments in seismic monitoring for risk reduction

    USGS Publications Warehouse

    Celebi, M.

    2007-01-01

    This paper presents recent state-of-the-art developments to obtain displacements and drift ratios for seismic monitoring and damage assessment of buildings. In most cases, decisions on safety of buildings following seismic events are based on visual inspections of the structures. Real-time instrumental measurements using GPS or double integration of accelerations, however, offer a viable alternative. Relevant parameters, such as the type of connections and structural characteristics (including storey geometry), can be estimated to compute drifts corresponding to several pre-selected threshold stages of damage. Drift ratios determined from real-time monitoring can then be compared to these thresholds in order to estimate damage conditions drift ratios. This approach is demonstrated in three steel frame buildings in San Francisco, California. Recently recorded data of strong shaking from these buildings indicate that the monitoring system can be a useful tool in rapid assessment of buildings and other structures following an earthquake. Such systems can also be used for risk monitoring, as a method to assess performance-based design and analysis procedures, for long-term assessment of structural characteristics of a building, and as a possible long-term damage detection tool.

  20. Stringent Mitigation Policy Implied By Temperature Impacts on Economic Growth

    NASA Astrophysics Data System (ADS)

    Moore, F.; Turner, D.

    2014-12-01

    Integrated assessment models (IAMs) compare the costs of greenhouse gas mitigation with damages from climate change in order to evaluate the social welfare implications of climate policy proposals and inform optimal emissions reduction trajectories. However, these models have been criticized for lacking a strong empirical basis for their damage functions, which do little to alter assumptions of sustained GDP growth, even under extreme temperature scenarios. We implement empirical estimates of temperature effects on GDP growth-rates in the Dynamic Integrated Climate and Economy (DICE) model via two pathways, total factor productivity (TFP) growth and capital depreciation. Even under optimistic adaptation assumptions, this damage specification implies that optimal climate policy involves the elimination of emissions in the near future, the stabilization of global temperature change below 2°C, and a social cost of carbon (SCC) an order of magnitude larger than previous estimates. A sensitivity analysis shows that the magnitude of growth effects, the rate of adaptation, and the dynamic interaction between damages from warming and GDP are three critical uncertainties and an important focus for future research.

  1. Medical malpractice reform and employer-sponsored health insurance premiums.

    PubMed

    Morrisey, Michael A; Kilgore, Meredith L; Nelson, Leonard Jack

    2008-12-01

    Tort reform may affect health insurance premiums both by reducing medical malpractice premiums and by reducing the extent of defensive medicine. The objective of this study is to estimate the effects of noneconomic damage caps on the premiums for employer-sponsored health insurance. Employer premium data and plan/establishment characteristics were obtained from the 1999 through 2004 Kaiser/HRET Employer Health Insurance Surveys. Damage caps were obtained and dated based on state annotated codes, statutes, and judicial decisions. Fixed effects regression models were run to estimate the effects of the size of inflation-adjusted damage caps on the weighted average single premiums. State tort reform laws were identified using Westlaw, LEXIS, and statutory compilations. Legislative repeal and amendment of statutes and court decisions resulting in the overturning or repealing state statutes were also identified using LEXIS. Using a variety of empirical specifications, there was no statistically significant evidence that noneconomic damage caps exerted any meaningful influence on the cost of employer-sponsored health insurance. The findings suggest that tort reforms have not translated into insurance savings.

  2. Contribution of insectivorous avifauna to top down control of Lindera benzoin herbivores at forest edge and interior habitats

    NASA Astrophysics Data System (ADS)

    Skoczylas, Daniel R.; Muth, Norris Z.; Niesenbaum, Richard A.

    2007-11-01

    Predation of herbivorous Lepidoptera larvae by insectivorous avifauna was estimated on Lindera benzoin in edge and interior habitats at two sites in eastern Pennsylvania (USA). Clay baits modeled after Epimecis hortaria (Geometridae) larvae, the primary herbivore of L. benzoin at our study sites, were used to estimate predation by birds. In both habitat types, models were placed on uninjured L. benzoin leaves as well as on leaves that had prior insect herbivore damage. Rates of model attack were greater, and model longevity reduced, in forest edge plots compared to interiors. Naturally occurring herbivore damage on L. benzoin was greater in forest interiors. However, model attack was not significantly greater on leaves with prior herbivory damage, suggesting that birds do not effectively use this type of leaf damage as a cue in their foraging. Our findings are consistent with a contribution of bird predation towards top-down control of herbivory in this system. We further discuss these results in a broader context considering the possible effects of habitat type on leaf quality, leaf defense, and herbivore performance.

  3. Observation-Corrected Precipitation Estimates in GEOS-5

    NASA Technical Reports Server (NTRS)

    Reichle, Rolf H.; Liu, Qing

    2014-01-01

    Several GEOS-5 applications, including the GEOS-5 seasonal forecasting system and the MERRA-Land data product, rely on global precipitation data that have been corrected with satellite and or gauge-based precipitation observations. This document describes the methodology used to generate the corrected precipitation estimates and their use in GEOS-5 applications. The corrected precipitation estimates are derived by disaggregating publicly available, observationally based, global precipitation products from daily or pentad totals to hourly accumulations using background precipitation estimates from the GEOS-5 atmospheric data assimilation system. Depending on the specific combination of the observational precipitation product and the GEOS-5 background estimates, the observational product may also be downscaled in space. The resulting corrected precipitation data product is at the finer temporal and spatial resolution of the GEOS-5 background and matches the observed precipitation at the coarser scale of the observational product, separately for each day (or pentad) and each grid cell.

  4. Damage evaluation of fiber reinforced plastic-confined circular concrete-filled steel tubular columns under cyclic loading using the acoustic emission technique

    NASA Astrophysics Data System (ADS)

    Li, Dongsheng; Du, Fangzhu; Ou, Jinping

    2017-03-01

    Glass-fiber reinforced plastic (GFRP)-confined circular concrete-filled steel tubular (CCFT) columns comprise of concrete, steel, and GFRP and show complex failure mechanics under cyclic loading. This paper investigated the failure mechanism and damage evolution of GFRP-CCFT columns by performing uniaxial cyclic loading tests that were monitored using the acoustic emission (AE) technique. Characteristic AE parameters were obtained during the damage evolution of GFRP-CCFT columns. Based on the relationship between the loading curve and these parameters, the damage evolution of GFRP-CCFT columns was classified into three stages that represented different damage degrees. Damage evolution and failure mode were investigated by analyzing the b-value and the ratio of rise time to waveform amplitude and average frequency. The damage severity of GFRP-CCFT columns were quantitatively estimated according to the modified index of damage and NDIS-2421 damage assessment criteria corresponding to each loading step. The proposed method can explain the damage evolution and failure mechanism for GFRP-CCFT columns and provide critical warning information for composite structures.

  5. Modeling Patient-Specific Magnetic Drug Targeting Within the Intracranial Vasculature

    PubMed Central

    Patronis, Alexander; Richardson, Robin A.; Schmieschek, Sebastian; Wylie, Brian J. N.; Nash, Rupert W.; Coveney, Peter V.

    2018-01-01

    Drug targeting promises to substantially enhance future therapies, for example through the focussing of chemotherapeutic drugs at the site of a tumor, thus reducing the exposure of healthy tissue to unwanted damage. Promising work on the steering of medication in the human body employs magnetic fields acting on nanoparticles made of paramagnetic materials. We develop a computational tool to aid in the optimization of the physical parameters of these particles and the magnetic configuration, estimating the fraction of particles reaching a given target site in a large patient-specific vascular system for different physiological states (heart rate, cardiac output, etc.). We demonstrate the excellent computational performance of our model by its application to the simulation of paramagnetic-nanoparticle-laden flows in a circle of Willis geometry obtained from an MRI scan. The results suggest a strong dependence of the particle density at the target site on the strength of the magnetic forcing and the velocity of the background fluid flow. PMID:29725303

  6. Modeling Patient-Specific Magnetic Drug Targeting Within the Intracranial Vasculature.

    PubMed

    Patronis, Alexander; Richardson, Robin A; Schmieschek, Sebastian; Wylie, Brian J N; Nash, Rupert W; Coveney, Peter V

    2018-01-01

    Drug targeting promises to substantially enhance future therapies, for example through the focussing of chemotherapeutic drugs at the site of a tumor, thus reducing the exposure of healthy tissue to unwanted damage. Promising work on the steering of medication in the human body employs magnetic fields acting on nanoparticles made of paramagnetic materials. We develop a computational tool to aid in the optimization of the physical parameters of these particles and the magnetic configuration, estimating the fraction of particles reaching a given target site in a large patient-specific vascular system for different physiological states (heart rate, cardiac output, etc.). We demonstrate the excellent computational performance of our model by its application to the simulation of paramagnetic-nanoparticle-laden flows in a circle of Willis geometry obtained from an MRI scan. The results suggest a strong dependence of the particle density at the target site on the strength of the magnetic forcing and the velocity of the background fluid flow.

  7. In-Situ NDE Characterization of Kevlar and Carbon Composite Micromechanics for Improved COPV Health Monitoring

    NASA Technical Reports Server (NTRS)

    Waller, Jess M.; Saulsberry, Regor L.

    2009-01-01

    This project is a subtask of a multi-center project to advance the state-of-the-art by developing NDE techniques that are capable of evaluating stress rupture (SR) degradation in Kevlar/epoxy (K/Ep) composite overwrapped pressure vessels (COPVs), and damage progression in carbon/epoxy (C/Ep) COPVs. In this subtask, acoustic emission (AE) data acquired during intermittent load hold tensile testing of K/Ep and C/Ep composite tow materials-of-construction used in COPV fabrication were analyzed to monitor progressive damage during the approach to tensile failure. Insight into the progressive damage of composite tow was gained by monitoring AE event rate, energy, source location, and frequency. Source location based on arrival time data was used to discern between significant AE attributable to microstructural damage and spurious AE attributable to background and grip noise. One of the significant findings was the observation of increasing violation of the Kaiser effect (Felicity ratio < 1.0) with damage accumulation.

  8. Solar cell radiation handbook

    NASA Technical Reports Server (NTRS)

    Carter, J. R., Jr.; Tada, H. Y.

    1973-01-01

    A method is presented for predicting the degradation of a solar array in a space radiation environment. Solar cell technology which emphasizes the cell parameters that degrade in a radiation environment, is discussed along with the experimental techniques used in the evaluation of radiation effects. Other topics discussed include: theoretical aspects of radiation damage, methods for developing relative damage coefficients, nature of the space radiation environment, method of calculating equivalent fluence from electron and proton energy spectrums and relative damage coefficients, and comparison of flight data with estimated degradation.

  9. Multiscale modelling of Flow-Induced Blood Cell Damage

    NASA Astrophysics Data System (ADS)

    Liu, Yaling; Sohrabi, Salman

    2017-11-01

    We study red blood cell (RBC) damage and hemolysis at cellular level. Under high shear rates, pores form on RBC membranes through which hemoglobin (Hb) leaks out and increases free Hb content of plasma leading to hemolysis. By coupling lattice Boltzmann and spring connected network models through immersed boundary method, we estimate hemolysis of a single RBC under various shear rates. The developed cellular damage model can be used as a predictive tool for hydrodynamic and hematologic design optimization of blood-wetting medical devices.

  10. Flood Control, State Road and Ebner Coulees, La Crosse, Wisconsin, General Design Memorandum. Phase I. Plan Formulation and Hydrology and Draft Environmental Impact Statement.

    DTIC Science & Technology

    1982-04-01

    development of the floodplain by use of appropriate floodplain management techniques to reduce flood losses . h. In the event of future development or...the total annual flood damages in the study area. These losses include physical damages to land, buildings, equipment, and stocks of merchandise as...well as the loss of wages and business profits and the costs of emergency protection. Average annual commercial damages are estimated at $253,000. The

  11. 99. VIEW OF NORTHWEST SIDE OF PIER, LOOKING EAST FROM ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    99. VIEW OF NORTHWEST SIDE OF PIER, LOOKING EAST FROM STORM-DAMAGED END. 3RD TEE BUILDINGS IN BACKGROUND - Huntington Beach Municipal Pier, Pacific Coast Highway at Main Street, Huntington Beach, Orange County, CA

  12. Estimating representative background PM2.5 concentration in heavily polluted areas using baseline separation technique and chemical mass balance model

    NASA Astrophysics Data System (ADS)

    Gao, Shuang; Yang, Wen; Zhang, Hui; Sun, Yanling; Mao, Jian; Ma, Zhenxing; Cong, Zhiyuan; Zhang, Xian; Tian, Shasha; Azzi, Merched; Chen, Li; Bai, Zhipeng

    2018-02-01

    The determination of background concentration of PM2.5 is important to understand the contribution of local emission sources to total PM2.5 concentration. The purpose of this study was to exam the performance of baseline separation techniques to estimate PM2.5 background concentration. Five separation methods, which included recursive digital filters (Lyne-Hollick, one-parameter algorithm, and Boughton two-parameter algorithm), sliding interval and smoothed minima, were applied to one-year PM2.5 time-series data in two heavily polluted cities, Tianjin and Jinan. To obtain the proper filter parameters and recession constants for the separation techniques, we conducted regression analysis at a background site during the emission reduction period enforced by the Government for the 2014 Asia-Pacific Economic Cooperation (APEC) meeting in Beijing. Background concentrations in Tianjin and Jinan were then estimated by applying the determined filter parameters and recession constants. The chemical mass balance (CMB) model was also applied to ascertain the effectiveness of the new approach. Our results showed that the contribution of background PM concentration to ambient pollution was at a comparable level to the contribution obtained from the previous study. The best performance was achieved using the Boughton two-parameter algorithm. The background concentrations were estimated at (27 ± 2) μg/m3 for the whole year, (34 ± 4) μg/m3 for the heating period (winter), (21 ± 2) μg/m3 for the non-heating period (summer), and (25 ± 2) μg/m3 for the sandstorm period in Tianjin. The corresponding values in Jinan were (30 ± 3) μg/m3, (40 ± 4) μg/m3, (24 ± 5) μg/m3, and (26 ± 2) μg/m3, respectively. The study revealed that these baseline separation techniques are valid for estimating levels of PM2.5 air pollution, and that our proposed method has great potential for estimating the background level of other air pollutants.

  13. Estimates of over-diagnosis of breast cancer due to population-based mammography screening in South Australia after adjustment for lead time effects.

    PubMed

    Beckmann, Kerri; Duffy, Stephen W; Lynch, John; Hiller, Janet; Farshid, Gelareh; Roder, David

    2015-09-01

    To estimate over-diagnosis due to population-based mammography screening using a lead time adjustment approach, with lead time measures based on symptomatic cancers only. Women aged 40-84 in 1989-2009 in South Australia eligible for mammography screening. Numbers of observed and expected breast cancer cases were compared, after adjustment for lead time. Lead time effects were modelled using age-specific estimates of lead time (derived from interval cancer rates and predicted background incidence, using maximum likelihood methods) and screening sensitivity, projected background breast cancer incidence rates (in the absence of screening), and proportions screened, by age and calendar year. Lead time estimates were 12, 26, 43 and 53 months, for women aged 40-49, 50-59, 60-69 and 70-79 respectively. Background incidence rates were estimated to have increased by 0.9% and 1.2% per year for invasive and all breast cancer. Over-diagnosis among women aged 40-84 was estimated at 7.9% (0.1-12.0%) for invasive cases and 12.0% (5.7-15.4%) when including ductal carcinoma in-situ (DCIS). We estimated 8% over-diagnosis for invasive breast cancer and 12% inclusive of DCIS cancers due to mammography screening among women aged 40-84. These estimates may overstate the extent of over-diagnosis if the increasing prevalence of breast cancer risk factors has led to higher background incidence than projected. © The Author(s) 2015.

  14. Abundance and genetic damage of barn swallows from Fukushima

    PubMed Central

    Bonisoli-Alquati, A.; Koyama, K.; Tedeschi, D. J.; Kitamura, W.; Sukuzi, H.; Ostermiller, S.; Arai, E.; Møller, A. P.; Mousseau, T. A.

    2015-01-01

    A number of studies have assessed or modeled the distribution of the radionuclides released by the accident at the Fukushima-Daiichi Nuclear Power Plant (FDNPP). Few studies however have investigated its consequences for the local biota. We tested whether exposure of barn swallow (Hirundo rustica) nestlings to low dose ionizing radiation increased genetic damage to their peripheral erythrocytes. We estimated external radiation exposure by using thermoluminescent dosimeters, and by measuring radioactivity of the nest material. We then assessed DNA damage by means of the neutral comet assay. In addition, we conducted standard point-count censuses of barn swallows across environmental radiation levels, and estimated their abundance and local age ratio. Radioactivity of nest samples was in the range 479–143,349 Bq kg−1, while external exposure varied between 0.15 and 4.9 mGy. Exposure to radioactive contamination did not correlate with higher genetic damage in nestlings. However, at higher levels of radioactive contamination the number of barn swallows declined and the fraction of juveniles decreased, indicating lower survival and lower reproduction and/or fledging rate. Thus, genetic damage to nestlings does not explain the decline of barn swallows in contaminated areas, and a proximate mechanism for the demographic effects documented here remains to be clarified. PMID:25838205

  15. High-fidelity Modeling of Local Effects of Damage for Derated Offshore Wind Turbines

    NASA Astrophysics Data System (ADS)

    Richards, Phillip W.; Griffith, D. Todd; Hodges, Dewey H.

    2014-06-01

    Offshore wind power production is an attractive clean energy option, but the difficulty of access can lead to expensive and rare opportunities for maintenance. As part of the Structural Health and Prognostics Management (SHPM) project at Sandia National Laboratories, smart loads management (controls) are investigated for their potential to increase the fatigue life of offshore wind turbine rotor blades. Derating refers to altering the rotor angular speed and blade pitch to limit power production and loads on the rotor blades. High- fidelity analysis techniques like 3D finite element modeling (FEM) should be used alongside beam models of wind turbine blades to characterize these control strategies in terms of their effect to mitigate fatigue damage and extend life of turbine blades. This study will consider a commonly encountered damage type for wind turbine blades, the trailing edge disbond, and show how FEM can be used to quantify the effect of operations and control strategies designed to extend the fatigue life of damaged blades. The Virtual Crack Closure Technique (VCCT) will be used to post-process the displacement and stress results to provide estimates of damage severity/criticality and provide a means to estimate the fatigue life under a given operations and control strategy.

  16. Is organic farming safer to farmers’ health? A comparison between organic and traditional farming

    PubMed Central

    Costa, Carla; García-Lestón, Julia; Costa, Solange; Coelho, Patrícia; Silva, Susana; Valdiglesias, Vanessa; Mattei, Francesca; Dall’Armi, Valentina; Bonassi, Stefano; Laffon, Blanca; Snawder, John; Teixeira, João Paulo

    2015-01-01

    Background Exposure to pesticides is a major public health concern, because of the widespread distribution of these compounds and their possible long term effects. Recently, organic farming has been introduced as a consumer and environmental friendly agricultural system, although little is known about the effects on workers’ health. Objectives To evaluate genetic damage and immunological alterations in workers of both traditional and organic farming. Methods Eighty-five farmers exposed to several pesticides, thirty–six organic farmers and sixty-one controls took part in the study. Biomarkers of exposure (pyrethroids, organophosphates, carbamates, and thioethers in urine and butyrylcholinesterase activity in plasma), early effect (micronuclei in lymphocytes and reticulocytes, T-cell receptor mutation assay, chromosomal aberrations, comet assay and lymphocytes subpopulations) and susceptibility (genetic polymorphisms related to metabolism - EPHX1, GSTM1, GSTT1 and GSTP1 - and DNA repair – XRCC1 and XRCC2) were evaluated. Results When compared to controls and organic farmers, pesticide farmers presented a significant increase of micronuclei in lymphocytes (frequency ratio, FR=2.80) and reticulocytes (FR=1.89), chromosomal aberrations (FR=2.19), DNA damage assessed by comet assay (mean ratio, MR=1.71), and a significant decrease in the proportion of B lymphocytes (MR=0.88). Overall, organic farmers presented similar levels of genetic damage as controls, in some cases modulated by GSTT1 and GSTM1, GSTP1 105Ile/Ile and XRCC1 399Gln/Gln genotypes. Conclusions Results confirmed the increased presence of DNA damage in farmers exposed to pesticides, and showed as exposure conditions and genetic background influence observed effects. Findings from this study indicate that no evident genetic or immunologic damage can be observed in organic farmers. PMID:24576785

  17. Grinding damage assessment for CAD-CAM restorative materials.

    PubMed

    Curran, Philippe; Cattani-Lorente, Maria; Anselm Wiskott, H W; Durual, Stéphane; Scherrer, Susanne S

    2017-03-01

    To assess surface/subsurface damage after grinding with diamond discs on five CAD-CAM restorative materials and to estimate potential losses in strength based on crack size measurements of the generated damage. The materials tested were: Lithium disilicate (LIT) glass-ceramic (e.max CAD), leucite glass-ceramic (LEU) (Empress CAD), feldspar ceramic (VM2) (Vita Mark II), feldspar ceramic-resin infiltrated (EN) (Enamic) and a composite reinforced with nano ceramics (LU) (Lava Ultimate). Specimens were cut from CAD-CAM blocs and pair-wise mirror polished for the bonded interface technique. Top surfaces were ground with diamond discs of respectively 75, 54 and 18μm. Chip damage was measured on the bonded interface using SEM. Fracture mechanics relationships were used to estimate fracture stresses based on average and maximum chip depths assuming these to represent strength limiting flaws subjected to tension and to calculate potential losses in strength compared to manufacturer's data. Grinding with a 75μm diamond disc induced on a bonded interface critical chips averaging 100μm with a potential strength loss estimated between 33% and 54% for all three glass-ceramics (LIT, LEU, VM2). The softer materials EN and LU were little damage susceptible with chips averaging respectively 26μm and 17μm with no loss in strength. Grinding with 18μm diamond discs was still quite detrimental for LIT with average chip sizes of 43μm and a potential strength loss of 42%. It is essential to understand that when grinding glass-ceramics or feldspar ceramics with diamond discs surface and subsurface damage are induced which have the potential of lowering the strength of the ceramic. Careful polishing steps should be carried out after grinding especially when dealing with glass-ceramics. Copyright © 2017 The Academy of Dental Materials. Published by Elsevier Ltd. All rights reserved.

  18. 15 CFR 990.63 - Discounting and compounding.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... NATURAL RESOURCE DAMAGE ASSESSMENTS Restoration Implementation Phase § 990.63 Discounting and compounding. (a) Estimated future restoration costs. When determining estimated future costs of implementing a Final Restoration Plan, trustees must discount such future costs back to the date the demand is...

  19. Floods of March 1978, in the Maumee River basin, northeastern Indiana

    USGS Publications Warehouse

    Hoggatt, Richard Earl

    1981-01-01

    Floods in the Maumee River basin in northeastern Indiana in March 1978 resulted in heavy damage in Fort Wayne and surrounding areas. Flood damage in Fort Wayne was estimated by the Mayor to be 11 million dollars. Approximately 15 percent of the city was inundated, and 2,400 of its 190,000 residents were forced to leave their homes. The estimate of damage in Adams and Allen Counties by Civil Defense officials was 44 million dollars. The Maumee River at New Haven exceeded the peak stage of record, 21.4 feet, by 2.2 feet. The peak discharge at this stream-gaging station, 22,400 cubic feet per second, was about equal to that of a 75-year flood. Recurrence intervals of peak flows on streams tributary to the Maumee River ranged from 5 to 50 years. Records of peak and daily discharges and some precipitation data are given in this report. 

  20. Calculation of wind speeds required to damage or destroy buildings

    NASA Astrophysics Data System (ADS)

    Liu, Henry

    Determination of wind speeds required to damage or destroy a building is important not only for the improvement of building design and construction but also for the estimation of wind speeds in tornadoes and other damaging storms. For instance, since 1973 the U.S. National Weather Service has been using the well-known Fujita scale (F scale) to estimate the maximum wind speeds of tornadoes [Fujita, 1981]. The F scale classifies tornadoes into 13 numbers, F-0 through F-12. The wind speed (maximum gust speed) associated with each F number is given in Table 1. Note that F-6 through F-12 are for wind speeds between 319 mi/hr (mph) and the sonic velocity (approximately 760 mph; 1 mph = 1.6 km/kr). However, since no tornadoes have been classified to exceed F-5, the F-6 through F-12 categories have no practical meaning [Fujita, 1981].

  1. Melt damage simulation of W-macrobrush and divertor gaps after multiple transient events in ITER

    NASA Astrophysics Data System (ADS)

    Bazylev, B. N.; Janeschitz, G.; Landman, I. S.; Loarte, A.; Pestchanyi, S. E.

    2007-06-01

    Tungsten in the form of macrobrush structure is foreseen as one of two candidate materials for the ITER divertor and dome. In ITER, even for moderate and weak ELMs when a thin shielding layer does not protect the armour surface from the dumped plasma, the main mechanisms of metallic target damage remain surface melting and melt motion erosion, which determines the lifetime of the plasma facing components. The melt erosion of W-macrobrush targets with different geometry of brush surface under the heat loads caused by weak ELMs is numerically investigated using the modified code MEMOS. The optimal angle of brush surface inclination that provides a minimum of surface roughness is estimated for given inclination angles of impacting plasma stream and given parameters of the macrobrush target. For multiple disruptions the damage of the dome gaps and the gaps between divertor cassettes caused by the radiation impact is estimated.

  2. Generating an agricultural risk map based on limited ecological information: A case study using Sicyos angulatus.

    PubMed

    Osawa, Takeshi; Okawa, Shigenori; Kurokawa, Shunji; Ando, Shinichiro

    2016-12-01

    In this study, we propose a method for estimating the risk of agricultural damage caused by an invasive species when species-specific information is lacking. We defined the "risk" as the product of the invasion probability and the area of potentially damaged crop for production. As a case study, we estimated the risk imposed by an invasive weed, Sicyos angulatus, based on simple cellular simulations and governmental data on the area of crop that could potentially be damaged in Miyagi Prefecture, Japan. Simulation results revealed that the current distribution range was sufficiently accurate for practical purposes. Using these results and records of crop areas, we present risk maps for S. angulatus in agricultural fields. Managers will be able to use these maps to rapidly establish a management plan with minimal cost. Our approach will be valuable for establishing a management plan before or during the early stages of invasion.

  3. A Review of Spectral Methods for Variable Amplitude Fatigue Prediction and New Results

    NASA Technical Reports Server (NTRS)

    Larsen, Curtis E.; Irvine, Tom

    2013-01-01

    A comprehensive review of the available methods for estimating fatigue damage from variable amplitude loading is presented. The dependence of fatigue damage accumulation on power spectral density (psd) is investigated for random processes relevant to real structures such as in offshore or aerospace applications. Beginning with the Rayleigh (or narrow band) approximation, attempts at improved approximations or corrections to the Rayleigh approximation are examined by comparison to rainflow analysis of time histories simulated from psd functions representative of simple theoretical and real world applications. Spectral methods investigated include corrections by Wirsching and Light, Ortiz and Chen, the Dirlik formula, and the Single-Moment method, among other more recent proposed methods. Good agreement is obtained between the spectral methods and the time-domain rainflow identification for most cases, with some limitations. Guidelines are given for using the several spectral methods to increase confidence in the damage estimate.

  4. Potential damage to modern building materials from 21st century air pollution.

    PubMed

    Brimblecombe, Peter; Grossi, Carlota Maria

    2010-01-21

    The evolution of damage to building materials has been estimated for the 21st century, with a particular focus on aluminum, zinc, copper, plastic, paint, and rubber in urban areas. We set idealized air pollution and climates to represent London and Prague across the period 1950-2100. Environmental parameters were used to estimate future recession, corrosion, and loss of properties through published damage or dose-response functions. The 21st century seems to provide a less aggressive environment for stone and metals than recent times. Improvements in air quality are the most relevant drivers for this amelioration. Changes in climate predicted for the 21st century do not alter this picture. On the other hand, polymeric materials, plastic, paint, and rubber might show slightly increased rates of degradation, to some extent the result of enhanced oxidant concentrations, but also the possibility of contributions from more solar radiation.

  5. Automatic detection and classification of damage zone(s) for incorporating in digital image correlation technique

    NASA Astrophysics Data System (ADS)

    Bhattacharjee, Sudipta; Deb, Debasis

    2016-07-01

    Digital image correlation (DIC) is a technique developed for monitoring surface deformation/displacement of an object under loading conditions. This method is further refined to make it capable of handling discontinuities on the surface of the sample. A damage zone is referred to a surface area fractured and opened in due course of loading. In this study, an algorithm is presented to automatically detect multiple damage zones in deformed image. The algorithm identifies the pixels located inside these zones and eliminate them from FEM-DIC processes. The proposed algorithm is successfully implemented on several damaged samples to estimate displacement fields of an object under loading conditions. This study shows that displacement fields represent the damage conditions reasonably well as compared to regular FEM-DIC technique without considering the damage zones.

  6. Lamb-Wave-Based Tomographic Imaging Techniques for Hole-Edge Corrosion Monitoring in Plate Structures

    PubMed Central

    Wang, Dengjiang; Zhang, Weifang; Wang, Xiangyu; Sun, Bo

    2016-01-01

    This study presents a novel monitoring method for hole-edge corrosion damage in plate structures based on Lamb wave tomographic imaging techniques. An experimental procedure with a cross-hole layout using 16 piezoelectric transducers (PZTs) was designed. The A0 mode of the Lamb wave was selected, which is sensitive to thickness-loss damage. The iterative algebraic reconstruction technique (ART) method was used to locate and quantify the corrosion damage at the edge of the hole. Hydrofluoric acid with a concentration of 20% was used to corrode the specimen artificially. To estimate the effectiveness of the proposed method, the real corrosion damage was compared with the predicted corrosion damage based on the tomographic method. The results show that the Lamb-wave-based tomographic method can be used to monitor the hole-edge corrosion damage accurately. PMID:28774041

  7. Electron radiation damage mechanisms in 2D MoSe2

    NASA Astrophysics Data System (ADS)

    Lehnert, T.; Lehtinen, O.; Algara-Siller, G.; Kaiser, U.

    2017-01-01

    The contributions of different damage mechanisms in single-layer MoSe2 were studied by investigating different MoSe2/graphene heterostructures by the aberration-corrected high-resolution transmission electron microscopy (AC-HRTEM) at 80 keV. The damage cross-sections were determined by direct counting of atoms in the AC-HRTEM images. The contributions of damage mechanisms such as knock-on damage or ionization effects were estimated by comparing the damage rates in different heterostructure configurations, similarly to what has been earlier done with MoS2. The behaviour of MoSe2 was found to be nearly identical to that of MoS2, which is an unexpected result, as the knock-on mechanism should be suppressed in MoSe2 due to the high mass of Se, as compared to S.

  8. Spatially resolved air-water emissions tradeoffs improve regulatory impact analyses for electricity generation.

    PubMed

    Gingerich, Daniel B; Sun, Xiaodi; Behrer, A Patrick; Azevedo, Inês L; Mauter, Meagan S

    2017-02-21

    Coal-fired power plants (CFPPs) generate air, water, and solids emissions that impose substantial human health, environmental, and climate change (HEC) damages. This work demonstrates the importance of accounting for cross-media emissions tradeoffs, plant and regional emissions factors, and spatially variation in the marginal damages of air emissions when performing regulatory impact analyses for electric power generation. As a case study, we assess the benefits and costs of treating wet flue gas desulfurization (FGD) wastewater at US CFPPs using the two best available treatment technology options specified in the 2015 Effluent Limitation Guidelines (ELGs). We perform a life-cycle inventory of electricity and chemical inputs to FGD wastewater treatment processes and quantify the marginal HEC damages of associated air emissions. We combine these spatially resolved damage estimates with Environmental Protection Agency estimates of water quality benefits, fuel-switching benefits, and regulatory compliance costs. We estimate that the ELGs will impose average net costs of $3.01 per cubic meter for chemical precipitation and biological wastewater treatment and $11.26 per cubic meter for zero-liquid discharge wastewater treatment (expected cost-benefit ratios of 1.8 and 1.7, respectively), with damages concentrated in regions containing a high fraction of coal generation or a large chemical manufacturing industry. Findings of net cost for FGD wastewater treatment are robust to uncertainty in auxiliary power source, location of chemical manufacturing, and binding air emissions limits in noncompliant regions, among other variables. Future regulatory design will minimize compliance costs and HEC tradeoffs by regulating air, water, and solids emissions simultaneously and performing regulatory assessments that account for spatial variation in emissions impacts.

  9. Assessing the Cost of an Invasive Forest Pathogen: A Case Study with Oak Wilt

    NASA Astrophysics Data System (ADS)

    Haight, Robert G.; Homans, Frances R.; Horie, Tetsuya; Mehta, Shefali V.; Smith, David J.; Venette, Robert C.

    2011-03-01

    Economic assessment of damage caused by invasive alien species provides useful information to consider when determining whether management programs should be established, modified, or discontinued. We estimate the baseline economic damage from an invasive alien pathogen, Ceratocystis fagacearum, a fungus that causes oak wilt, which is a significant disease of oaks ( Quercus spp.) in the central United States. We focus on Anoka County, Minnesota, a 1,156 km2 mostly urban county in the Minneapolis-Saint Paul metropolitan region. We develop a landscape-level model of oak wilt spread that accounts for underground and overland pathogen transmission. We predict the economic damage of tree mortality from oak wilt spread in the absence of management during the period 2007-2016. Our metric of economic damage is removal cost, which is one component of the total economic loss from tree mortality. We estimate that Anoka County has 5.92 million oak trees and 885 active oak wilt pockets covering 5.47 km2 in 2007. The likelihood that landowners remove infected oaks varies by land use and ranges from 86% on developed land to 57% on forest land. Over the next decade, depending on the rates of oak wilt pocket establishment and expansion, 76-266 thousand trees will be infected with discounted removal cost of 18-60 million. Although our predictions of removal costs are substantial, they are lower bounds on the total economic loss from tree mortality because we do not estimate economic losses from reduced services and increased hazards. Our predictions suggest that there are significant economic benefits, in terms of damage reduction, from preventing new pocket establishment or slowing the radial growth of existing pockets.

  10. Strong ground motion in Port-au-Prince, Haiti, during the M7.0 12 January 2010 Haiti earthquake

    USGS Publications Warehouse

    Hough, Susan E; Given, Doug; Taniguchi, Tomoyo; Altidor, J.R.; Anglade, Dieuseul; Mildor, S-L.

    2011-01-01

    No strong motion records are available for the 12 January 2010 M7.0 Haiti earthquake. We use aftershock recordings as well as detailed considerations of damage to estimate the severity and distribution of mainshock shaking in Port-au-Prince. Relative to ground motions at a hard - rock reference site, peak accelerations are amplified by a factor of approximately 2 at sites on low-lying deposits in central Port-au-Prince and by a factor of 2.5 - 3.5 on a steep foothill ridge in the southern Port-au-Prince metropolitan region. The observed amplification along the ridge cannot be explained by sediment - induced amplification , but is consistent with predicted topographic amplification by a steep, narrow ridge. Although damage was largely a consequence of poor construction , the damage pattern inferred from analysis of remote sensing imagery provides evidence for a correspondence between small-scale (0.1 - 1.0 km) topographic relief and high damage. Mainshock shaking intensity can be estimated crudely from a consideration of macroseismic effects . We further present detailed, quantitative analysis of the marks left on a tile floor by an industrial battery rack displaced during the mainshock, at the location where we observed the highest weak motion amplifications. Results of this analysis indicate that mainshock shaking was significantly higher at this location (~0.5 g , MMI VIII) relative to the shaking in parts of Port-au-Prince that experienced light damage. Our results further illustrate how observations of rigid body horizontal displacement during earthquakes can be used to estimate peak ground accelerations in the absence of instrumental data .

  11. Spatially resolved air-water emissions tradeoffs improve regulatory impact analyses for electricity generation

    PubMed Central

    Gingerich, Daniel B.; Behrer, A. Patrick; Azevedo, Inês L.

    2017-01-01

    Coal-fired power plants (CFPPs) generate air, water, and solids emissions that impose substantial human health, environmental, and climate change (HEC) damages. This work demonstrates the importance of accounting for cross-media emissions tradeoffs, plant and regional emissions factors, and spatially variation in the marginal damages of air emissions when performing regulatory impact analyses for electric power generation. As a case study, we assess the benefits and costs of treating wet flue gas desulfurization (FGD) wastewater at US CFPPs using the two best available treatment technology options specified in the 2015 Effluent Limitation Guidelines (ELGs). We perform a life-cycle inventory of electricity and chemical inputs to FGD wastewater treatment processes and quantify the marginal HEC damages of associated air emissions. We combine these spatially resolved damage estimates with Environmental Protection Agency estimates of water quality benefits, fuel-switching benefits, and regulatory compliance costs. We estimate that the ELGs will impose average net costs of $3.01 per cubic meter for chemical precipitation and biological wastewater treatment and $11.26 per cubic meter for zero-liquid discharge wastewater treatment (expected cost-benefit ratios of 1.8 and 1.7, respectively), with damages concentrated in regions containing a high fraction of coal generation or a large chemical manufacturing industry. Findings of net cost for FGD wastewater treatment are robust to uncertainty in auxiliary power source, location of chemical manufacturing, and binding air emissions limits in noncompliant regions, among other variables. Future regulatory design will minimize compliance costs and HEC tradeoffs by regulating air, water, and solids emissions simultaneously and performing regulatory assessments that account for spatial variation in emissions impacts. PMID:28167772

  12. Using the USGS Seismic Risk Web Application to estimate aftershock damage

    USGS Publications Warehouse

    McGowan, Sean M.; Luco, Nicolas

    2014-01-01

    The U.S. Geological Survey (USGS) Engineering Risk Assessment Project has developed the Seismic Risk Web Application to combine earthquake hazard and structural fragility information in order to calculate the risk of earthquake damage to structures. Enabling users to incorporate their own hazard and fragility information into the calculations will make it possible to quantify (in near real-time) the risk of additional damage to structures caused by aftershocks following significant earthquakes. Results can quickly be shared with stakeholders to illustrate the impact of elevated ground motion hazard and earthquake-compromised structural integrity on the risk of damage during a short-term, post-earthquake time horizon.

  13. Baseline frequency of chromosomal aberrations and sister chromatid exchanges in peripheral blood lymphocytes of healthy individuals living in Turin (North-Western Italy): assessment of the effects of age, sex and GSTs gene polymorphisms on the levels of genomic damage.

    PubMed

    Santovito, Alfredo; Cervella, Piero; Delpero, Massimiliano

    2016-05-01

    The increased exposure to environmental pollutants has led to the awareness of the necessity for constant monitoring of human populations, especially those living in urban areas. This study evaluated the background levels of genomic damage in a sample of healthy subjects living in the urban area of Turin (Italy). The association between DNA damage with age, sex and GSTs polymorphisms was assessed. One hundred and one individuals were randomly sampled. Sister Chromatid Exchanges (SCEs) and Chromosomal Aberrations (CAs) assays, as well as genotyping of GSTT1 and GSTM1 genes, were performed. Mean values of SCEs and CAs were 5.137 ± 0.166 and 0.018 ± 0.002, respectively. Results showed age and gender associated with higher frequencies of these two cytogenetic markers. The eldest subjects (51-65 years) showed significantly higher levels of genomic damage than younger individuals. GSTs polymorphisms did not appear to significantly influence the frequencies of either markers. The CAs background frequency observed in this study is one of the highest reported among European populations. Turin is one of the most polluted cities in Europe in terms of air fine PM10 and ozone and the clastogenic potential of these pollutants may explain the high frequencies of chromosomal rearrangements reported here.

  14. Three essays on utility regulation

    NASA Astrophysics Data System (ADS)

    Hlasny, Vladimir

    To induce utilities in the gas distribution market to operate efficiently, US states have deployed consumer choice programs, price caps, and variations of sliding scale plans. My first essay studies the impact of these restructuring and deregulation efforts on consumer rates, using panel data from a custom survey of state commissions and the Department of Energy. I estimate the residential, small commercial and industrial price equations jointly, and use instrumental variables to control for the potentially endogenous demand and status of deregulation. Consumer choice programs lower the prices by 2.2-20.1% compared to the rate of return regulation, benefiting industrial consumers the most and households the least. These effects appear even one to two years prior to the programs' implementation, and become stronger over time. Price caps lower all prices by 0.0-20.0%, with the same ranking. The impacts of sliding scale plans are close to zero, between -2.6% and +4.0% The second paper evaluates health damages caused by air concentrations of SO2 under three alternative environmental policies leading to identical aggregate emissions: emission caps, a nationwide emission tax, and a system of tradable emission allowances such as the one currently used in the US. The numerical model of the industry finds generators' output, participation in energy trade and SO2 abatement effort under each policy. The resulting SO2 concentrations are used to derive the aggregate health damages using estimates in the medical literature. SO2 concentrations vary across policies even when the aggregate emissions are the same. These variations translate into substantially different losses for any individual state, and, nationwide, to hundreds of millions of dollars of difference in aggregate damages. Emission caps are found to lead to the lowest damages, outperforming the currently used system of allowances by 452 million. A uniform emission tax leads to very similar damages as the system of tradable allowances, in agreement with the theory. These results are consistent with prior academic studies, that emission allowances and uniform taxes may lead to higher damages than regulatory instruments that control regional emissions more closely. In terms of SO2 concentrations and health impacts, emission caps are shown to favor the southern and southeastern states, where they deliver 840 million lower damages than the system of allowances or an emission tax, while they deliver 390 million higher damages in the northern and northeastern states. In the third essay I compute health damages from SO2 under different assumptions on the relationship between the concentration levels and their marginal health impacts. I evaluate SO2 concentration profiles resulting under the three policies in the previous chapter. Using the ranges of marginal damage estimates in medical literature, emission caps are shown to lead to the lowest damages under all considered slopes, although their benefit over the system of tradable allowances falls as the slope of the marginal damage function increases. With the maxiμm slope consistent with current medical data, the savings in damages under the emission caps in the southern states fall to 670 million compared the system of allowances, while the excess in damages they cause in the north and the northeast rises to $600 million.

  15. Vibration-based damage detection in wind turbine blades using Phase-based Motion Estimation and motion magnification

    NASA Astrophysics Data System (ADS)

    Sarrafi, Aral; Mao, Zhu; Niezrecki, Christopher; Poozesh, Peyman

    2018-05-01

    Vibration-based Structural Health Monitoring (SHM) techniques are among the most common approaches for structural damage identification. The presence of damage in structures may be identified by monitoring the changes in dynamic behavior subject to external loading, and is typically performed by using experimental modal analysis (EMA) or operational modal analysis (OMA). These tools for SHM normally require a limited number of physically attached transducers (e.g. accelerometers) in order to record the response of the structure for further analysis. Signal conditioners, wires, wireless receivers and a data acquisition system (DAQ) are also typical components of traditional sensing systems used in vibration-based SHM. However, instrumentation of lightweight structures with contact sensors such as accelerometers may induce mass-loading effects, and for large-scale structures, the instrumentation is labor intensive and time consuming. Achieving high spatial measurement resolution for a large-scale structure is not always feasible while working with traditional contact sensors, and there is also the potential for a lack of reliability associated with fixed contact sensors in outliving the life-span of the host structure. Among the state-of-the-art non-contact measurements, digital video cameras are able to rapidly collect high-density spatial information from structures remotely. In this paper, the subtle motions from recorded video (i.e. a sequence of images) are extracted by means of Phase-based Motion Estimation (PME) and the extracted information is used to conduct damage identification on a 2.3-m long Skystream® wind turbine blade (WTB). The PME and phased-based motion magnification approach estimates the structural motion from the captured sequence of images for both a baseline and damaged test cases on a wind turbine blade. Operational deflection shapes of the test articles are also quantified and compared for the baseline and damaged states. In addition, having proper lighting while working with high-speed cameras can be an issue, therefore image enhancement and contrast manipulation has also been performed to enhance the raw images. Ultimately, the extracted resonant frequencies and operational deflection shapes are used to detect the presence of damage, demonstrating the feasibility of implementing non-contact video measurements to perform realistic structural damage detection.

  16. A damage mechanics based approach to structural deterioration and reliability

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bhattcharya, B.; Ellingwood, B.

    1998-02-01

    Structural deterioration often occurs without perceptible manifestation. Continuum damage mechanics defines structural damage in terms of the material microstructure, and relates the damage variable to the macroscopic strength or stiffness of the structure. This enables one to predict the state of damage prior to the initiation of a macroscopic flaw, and allows one to estimate residual strength/service life of an existing structure. The accumulation of damage is a dissipative process that is governed by the laws of thermodynamics. Partial differential equations for damage growth in terms of the Helmholtz free energy are derived from fundamental thermodynamical conditions. Closed-form solutions tomore » the equations are obtained under uniaxial loading for ductile deformation damage as a function of plastic strain, for creep damage as a function of time, and for fatigue damage as function of number of cycles. The proposed damage growth model is extended into the stochastic domain by considering fluctuations in the free energy, and closed-form solutions of the resulting stochastic differential equation are obtained in each of the three cases mentioned above. A reliability analysis of a ring-stiffened cylindrical steel shell subjected to corrosion, accidental pressure, and temperature is performed.« less

  17. The Impact of Missing Background Data on Subpopulation Estimation

    ERIC Educational Resources Information Center

    Rutkowski, Leslie

    2011-01-01

    Although population modeling methods are well established, a paucity of literature appears to exist regarding the effect of missing background data on subpopulation achievement estimates. Using simulated data that follows typical large-scale assessment designs with known parameters and a number of missing conditions, this paper examines the extent…

  18. Background stratified Poisson regression analysis of cohort data.

    PubMed

    Richardson, David B; Langholz, Bryan

    2012-03-01

    Background stratified Poisson regression is an approach that has been used in the analysis of data derived from a variety of epidemiologically important studies of radiation-exposed populations, including uranium miners, nuclear industry workers, and atomic bomb survivors. We describe a novel approach to fit Poisson regression models that adjust for a set of covariates through background stratification while directly estimating the radiation-disease association of primary interest. The approach makes use of an expression for the Poisson likelihood that treats the coefficients for stratum-specific indicator variables as 'nuisance' variables and avoids the need to explicitly estimate the coefficients for these stratum-specific parameters. Log-linear models, as well as other general relative rate models, are accommodated. This approach is illustrated using data from the Life Span Study of Japanese atomic bomb survivors and data from a study of underground uranium miners. The point estimate and confidence interval obtained from this 'conditional' regression approach are identical to the values obtained using unconditional Poisson regression with model terms for each background stratum. Moreover, it is shown that the proposed approach allows estimation of background stratified Poisson regression models of non-standard form, such as models that parameterize latency effects, as well as regression models in which the number of strata is large, thereby overcoming the limitations of previously available statistical software for fitting background stratified Poisson regression models.

  19. Does renal ageing affect survival?

    PubMed

    Razzaque, M Shawkat

    2007-10-01

    The effects of ageing on progressive deterioration of renal function, both in human and experimental animals, are described elsewhere, but the effect of renal damage on overall survival and longevity is not yet clearly established. The wild-type animals of various genetic backgrounds, fed with regular diet, overtime develop severe age-associated nephropathy, that include but not limited to inflammatory cell infiltration, glomerulosclerosis, and tubulointerstitial fibrosis. Such renal damage significantly reduces their survival. Reducing renal damage, either by caloric restriction or by suppressing growth hormone (GH)/insulin-like growth factor-1 (IGF-1) activity could significantly enhance the longevity of these animals. Available survival studies using experimental animals clearly suggest that kidney pathology is one of the important non-neoplastic lesions that could affect overall survival, and that restoration of renal function by preventing kidney damage could significantly extend longevity. Careful long-term studies are needed to determine the human relevance of these experimental studies.

  20. Predicting Avoidance of Skin Damage Feedback among College Students

    PubMed Central

    Dwyer, Laura A.; Shepperd, James A.; Stock, Michelle L.

    2015-01-01

    Background Showing people a personal ultraviolet (UV) photograph depicting skin damage can be an effective method for changing sun protection cognitions and behaviors. Purpose We examined whether people opt not to see their UV photograph if given a choice. We also examined predictors of avoidance of skin damage feedback. Methods College students (N = 257) completed questionnaires, viewed example UV photographs, and received the opportunity to see a UV photograph of their face. Results Over one-third of participants opted not to see their UV photograph. Greater perceived risk of sun damage and having fewer coping resources corresponded with greater avoidance, particularly among participants who reported infrequent sun protection behavior. Conclusion The health benefits of UV photography are realized only if people are willing to view the photograph. Our findings suggest the need for interventions that increase receptivity to viewing one’s UV photograph. PMID:25894276

  1. Flood damage modeling based on expert knowledge: Insights from French damage model for agricultural sector

    NASA Astrophysics Data System (ADS)

    Grelot, Frédéric; Agenais, Anne-Laurence; Brémond, Pauline

    2015-04-01

    In France, since 2011, it is mandatory for local communities to conduct cost-benefit analysis (CBA) of their flood management projects, to make them eligible for financial support from the State. Meanwhile, as a support, the French Ministry in charge of Environment proposed a methodology to fulfill CBA. Like for many other countries, this methodology is based on the estimation of flood damage. However, existing models to estimate flood damage were judged not convenient for a national-wide use. As a consequence, the French Ministry in charge of Environment launched studies to develop damage models for different sectors, such as: residential sector, public infrastructures, agricultural sector, and commercial and industrial sector. In this presentation, we aim at presenting and discussing methodological choices of those damage models. They all share the same principle: no sufficient data from past events were available to build damage models on a statistical analysis, so modeling was based on expert knowledge. We will focus on the model built for agricultural activities and more precisely for agricultural lands. This model was based on feedback from 30 agricultural experts who experienced floods in their geographical areas. They were selected to have a representative experience of crops and flood conditions in France. The model is composed of: (i) damaging functions, which reveal physiological vulnerability of crops, (ii) action functions, which correspond to farmers' decision rules for carrying on crops after a flood, and (iii) economic agricultural data, which correspond to featured characteristics of crops in the geographical area where the flood management project studied takes place. The two first components are generic and the third one is specific to the area studied. It is, thus, possible to produce flood damage functions adapted to different agronomic and geographical contexts. In the end, the model was applied to obtain a pool of damage functions giving damage in euros by hectare for 14 agricultural lands categories. As a conclusion, we will discuss the validation step of the model. Although the model was validated by experts, we analyse how it could gain insight from comparison with past events.

  2. Flood damage modeling based on expert knowledge: Insights from French damage model for agricultural sector

    NASA Astrophysics Data System (ADS)

    Grelot, Frédéric; Agenais, Anne-Laurence; Brémond, Pauline

    2014-05-01

    In France, since 2011, it is mandatory for local communities to conduct cost-benefit analysis (CBA) of their flood management projects, to make them eligible for financial support from the State. Meanwhile, as a support, the French Ministry in charge of Environment proposed a methodology to fulfill CBA. Like for many other countries, this methodology is based on the estimation of flood damage. Howerver, existing models to estimate flood damage were judged not convenient for a national-wide use. As a consequence, the French Ministry in charge of Environment launched studies to develop damage models for different sectors, such as: residential sector, public infrastructures, agricultural sector, and commercial and industrial sector. In this presentation, we aim at presenting and discussing methodological choices of those damage models. They all share the same principle: no sufficient data from past events were available to build damage models on a statistical analysis, so modeling was based on expert knowledge. We will focus on the model built for agricultural activities and more precisely for agricultural lands. This model was based on feedback from 30 agricultural experts who experienced floods in their geographical areas. They were selected to have a representative experience of crops and flood conditions in France. The model is composed of: (i) damaging functions, which reveal physiological vulnerability of crops, (ii) action functions, which correspond to farmers' decision rules for carrying on crops after a flood, and (iii) economic agricultural data, which correspond to featured characteristics of crops in the geographical area where the flood management project studied takes place. The two first components are generic and the third one is specific to the area studied. It is, thus, possible to produce flood damage functions adapted to different agronomic and geographical contexts. In the end, the model was applied to obtain a pool of damage functions giving damage in euros by hectare for 14 agricultural lands categories. As a conclusion, we will discuss the validation step of the model. Although the model was validated by experts, we analyse how it could gain insight from comparison with past events.

  3. Merging National Forest and National Forest Health Inventories to Obtain an Integrated Forest Resource Inventory – Experiences from Bavaria, Slovenia and Sweden

    PubMed Central

    Kovač, Marko; Bauer, Arthur; Ståhl, Göran

    2014-01-01

    Backgrounds, Material and Methods To meet the demands of sustainable forest management and international commitments, European nations have designed a variety of forest-monitoring systems for specific needs. While the majority of countries are committed to independent, single-purpose inventorying, a minority of countries have merged their single-purpose forest inventory systems into integrated forest resource inventories. The statistical efficiencies of the Bavarian, Slovene and Swedish integrated forest resource inventory designs are investigated with the various statistical parameters of the variables of growing stock volume, shares of damaged trees, and deadwood volume. The parameters are derived by using the estimators for the given inventory designs. The required sample sizes are derived via the general formula for non-stratified independent samples and via statistical power analyses. The cost effectiveness of the designs is compared via two simple cost effectiveness ratios. Results In terms of precision, the most illustrative parameters of the variables are relative standard errors; their values range between 1% and 3% if the variables’ variations are low (s%<80%) and are higher in the case of higher variations. A comparison of the actual and required sample sizes shows that the actual sample sizes were deliberately set high to provide precise estimates for the majority of variables and strata. In turn, the successive inventories are statistically efficient, because they allow detecting the mean changes of variables with powers higher than 90%; the highest precision is attained for the changes of growing stock volume and the lowest for the changes of the shares of damaged trees. Two indicators of cost effectiveness also show that the time input spent for measuring one variable decreases with the complexity of inventories. Conclusion There is an increasing need for credible information on forest resources to be used for decision making and national and international policy making. Such information can be cost-efficiently provided through integrated forest resource inventories. PMID:24941120

  4. Genotoxic Effects in Swimmers Exposed to Disinfection By-products in Indoor Swimming Pools

    PubMed Central

    Kogevinas, Manolis; Villanueva, Cristina M.; Font-Ribera, Laia; Liviac, Danae; Bustamante, Mariona; Espinoza, Felicidad; Nieuwenhuijsen, Mark J.; Espinosa, Aina; Fernandez, Pilar; DeMarini, David M.; Grimalt, Joan O.; Grummt, Tamara; Marcos, Ricard

    2010-01-01

    Background Exposure to disinfection by-products (DBPs) in drinking water has been associated with cancer risk. A recent study (Villanueva et al. 2007; Am J Epidemiol 165:148–156) found an increased bladder cancer risk among subjects attending swimming pools relative to those not attending. Objectives We evaluated adults who swam in chlorinated pools to determine whether exposure to DBPs in pool water is associated with biomarkers of genotoxicity. Methods We collected blood, urine, and exhaled air samples from 49 nonsmoking adult volunteers before and after they swam for 40 min in an indoor chlorinated pool. We estimated associations between the concentrations of four trihalomethanes (THMs) in exhaled breath and changes in micronuclei (MN) and DNA damage (comet assay) in peripheral blood lymphocytes before and 1 hr after swimming; urine mutagenicity (Ames assay) before and 2 hr after swimming; and MN in exfoliated urothelial cells before and 2 weeks after swimming. We also estimated associations and interactions with polymorphisms in genes related to DNA repair or to DBP metabolism. Results After swimming, the total concentration of the four THMs in exhaled breath was seven times higher than before swimming. The change in the frequency of micronucleated lymphocytes after swimming increased in association with higher exhaled concentrations of the brominated THMs (p = 0.03 for bromodichloromethane, p = 0.05 for chlorodibromomethane, p = 0.01 for bromoform) but not chloroform. Swimming was not associated with DNA damage detectable by the comet assay. Urine mutagenicity increased significantly after swimming, in association with the higher concentration of exhaled bromoform (p = 0.004). We found no significant associations with changes in micronucleated urothelial cells. Conclusions Our findings support potential genotoxic effects of exposure to DBPs from swimming pools. The positive health effects gained by swimming could be increased by reducing the potential health risks of pool water. PMID:20833606

  5. Tornado Damage Assessment: Reconstructing the Wind Through Debris Tracking and Treefall Pattern Analysis

    NASA Astrophysics Data System (ADS)

    Godfrey, C. M.; Peterson, C. J.; Lombardo, F.

    2017-12-01

    Efforts to enhance the resilience of communities to tornadoes requires an understanding of the interconnected nature of debris and damage propagation in both the built and natural environment. A first step toward characterizing the interconnectedness of these elements within a given community involves detailed post-event surveys of tornado damage. Such damage surveys immediately followed the 22 January 2017 EF3 tornadoes in the southern Georgia towns of Nashville and Albany. After assigning EF-scale ratings to impacted structures, the authors geotagged hundreds of pieces of debris scattered around selected residential structures and outbuildings in each neighborhood and paired each piece of debris with its source structure. Detailed information on trees in the vicinity of the structures supplements the debris data, including the species, dimensions, location, fall direction, and level of damage. High-resolution satellite imagery helps to identify the location and fall direction of hundreds of additional forest trees. These debris and treefall patterns allow an estimation of the near-surface wind field using a Rankine vortex model coupled with both a tree stability model and an infrastructure fragility model that simulates debris flight. Comparisons between the modeled damage and the actual treefall and debris field show remarkable similarities for a selected set of vortex parameters, indicating the viability of this approach for estimating enhanced Fujita scale levels, determining the near-surface wind field of a tornado during its passage through a neighborhood, and identifying how debris may contribute to the overall risk from tornadoes.

  6. Estimating the probability of mountain pine beetle red-attack damage

    Treesearch

    Michael A Wulder; J. C. White; Barbara J Bentz; M. F. Alvarez; N. C. Coops

    2006-01-01

    Accurate spatial information on the location and extent of mountain pine beetle infestation is critical for the planning of mitigation and treatment activities. Areas of mixed forest and variable terrain present unique challenges for the detection and mapping of mountain pine beetle red-attack damage, as red-attack has a more heterogeneous distribution under these...

  7. Identifying Hail Signatures in Satellite Imagery from the 9-10 August 2011 Severe Weather Event

    NASA Technical Reports Server (NTRS)

    Dryden, Rachel L.; Molthan, Andrew L.; Cole, Tony A.; Bell, Jordan R.

    2014-01-01

    Hail scars are identifiable in MODIS satellite imagery based on NDVI change, which was dominantly negative. Hail damage spatially correlates with SPC hail reports and MESH. This study developed a proxy for quantifying crop loss at varying thresholds to address the gap between SPC damage estimates and insurance payouts.

  8. Uncertainty and Sensitivity of Direct Economic Flood Damages: the FloodRisk Free and Open-Source Software

    NASA Astrophysics Data System (ADS)

    Albano, R.; Sole, A.; Mancusi, L.; Cantisani, A.; Perrone, A.

    2017-12-01

    The considerable increase of flood damages in the the past decades has shifted in Europe the attention from protection against floods to managing flood risks. In this context, the expected damages assessment represents a crucial information within the overall flood risk management process. The present paper proposes an open source software, called FloodRisk, that is able to operatively support stakeholders in the decision making processes with a what-if approach by carrying out the rapid assessment of the flood consequences, in terms of direct economic damage and loss of human lives. The evaluation of the damage scenarios, trough the use of the GIS software proposed here, is essential for cost-benefit or multi-criteria analysis of risk mitigation alternatives. However, considering that quantitative assessment of flood damages scenarios is characterized by intrinsic uncertainty, a scheme has been developed to identify and quantify the role of the input parameters in the total uncertainty of flood loss model application in urban areas with mild terrain and complex topography. By the concept of parallel models, the contribution of different module and input parameters to the total uncertainty is quantified. The results of the present case study have exhibited a high epistemic uncertainty on the damage estimation module and, in particular, on the type and form of the utilized damage functions, which have been adapted and transferred from different geographic and socio-economic contexts because there aren't depth-damage functions that are specifically developed for Italy. Considering that uncertainty and sensitivity depend considerably on local characteristics, the epistemic uncertainty associated with the risk estimate is reduced by introducing additional information into the risk analysis. In the light of the obtained results, it is evident the need to produce and disseminate (open) data to develop micro-scale vulnerability curves. Moreover, the urgent need to push forward research into the implementation of methods and models for the assimilation of uncertainties in decision-making processes emerges.

  9. Damage detection of rotating wind turbine blades using local flexibility method and long-gauge fiber Bragg grating sensors

    NASA Astrophysics Data System (ADS)

    Hsu, Ting-Yu; Shiao, Shen-Yuan; Liao, Wen-I.

    2018-01-01

    Wind turbines are a cost-effective alternative energy source; however, their blades are susceptible to damage. Therefore, damage detection of wind turbine blades is of great importance for condition monitoring of wind turbines. Many vibration-based structural damage detection techniques have been proposed in the last two decades. The local flexibility method, which can determine local stiffness variations of beam-like structures by using measured modal parameters, is one of the most promising vibration-based approaches. The local flexibility method does not require a finite element model of the structure. A few structural modal parameters identified from the ambient vibration signals both before and after damage are required for this method. In this study, we propose a damage detection approach for rotating wind turbine blades using the local flexibility method based on the dynamic macro-strain signals measured by long-gauge fiber Bragg grating (FBG)-based sensors. A small wind turbine structure was constructed and excited using a shaking table to generate vibration signals. The structure was designed to have natural frequencies as close as possible to those of a typical 1.5 MW wind turbine in real scale. The optical fiber signal of the rotating blades was transmitted to the data acquisition system through a rotary joint fixed inside the hollow shaft of the wind turbine. Reversible damage was simulated by aluminum plates attached to some sections of the wind turbine blades. The damaged locations of the rotating blades were successfully detected using the proposed approach, with the extent of damage somewhat over-estimated. Nevertheless, although the specimen of wind turbine blades cannot represent a real one, the results still manifest that FBG-based macro-strain measurement has potential to be employed to obtain the modal parameters of the rotating wind turbines and then locations of wind turbine segments with a change of rigidity can be estimated effectively by utilizing these identified parameters.

  10. Model-Based Fatigue Prognosis of Fiber-Reinforced Laminates Exhibiting Concurrent Damage Mechanisms

    NASA Technical Reports Server (NTRS)

    Corbetta, M.; Sbarufatti, C.; Saxena, A.; Giglio, M.; Goebel, K.

    2016-01-01

    Prognostics of large composite structures is a topic of increasing interest in the field of structural health monitoring for aerospace, civil, and mechanical systems. Along with recent advancements in real-time structural health data acquisition and processing for damage detection and characterization, model-based stochastic methods for life prediction are showing promising results in the literature. Among various model-based approaches, particle-filtering algorithms are particularly capable in coping with uncertainties associated with the process. These include uncertainties about information on the damage extent and the inherent uncertainties of the damage propagation process. Some efforts have shown successful applications of particle filtering-based frameworks for predicting the matrix crack evolution and structural stiffness degradation caused by repetitive fatigue loads. Effects of other damage modes such as delamination, however, are not incorporated in these works. It is well established that delamination and matrix cracks not only co-exist in most laminate structures during the fatigue degradation process but also affect each other's progression. Furthermore, delamination significantly alters the stress-state in the laminates and accelerates the material degradation leading to catastrophic failure. Therefore, the work presented herein proposes a particle filtering-based framework for predicting a structure's remaining useful life with consideration of multiple co-existing damage-mechanisms. The framework uses an energy-based model from the composite modeling literature. The multiple damage-mode model has been shown to suitably estimate the energy release rate of cross-ply laminates as affected by matrix cracks and delamination modes. The model is also able to estimate the reduction in stiffness of the damaged laminate. This information is then used in the algorithms for life prediction capabilities. First, a brief summary of the energy-based damage model is provided. Then, the paper describes how the model is embedded within the prognostic framework and how the prognostics performance is assessed using observations from run-to-failure experiments

  11. HST/WFC3: understanding and mitigating radiation damage effects in the CCD detectors

    NASA Astrophysics Data System (ADS)

    Baggett, S. M.; Anderson, J.; Sosey, M.; Gosmeyer, C.; Bourque, M.; Bajaj, V.; Khandrika, H.; Martlin, C.

    2016-07-01

    At the heart of the Hubble Space Telescope Wide Field Camera 3 (HST/WFC3) UVIS channel is a 4096x4096 pixel e2v CCD array. While these detectors continue to perform extremely well after more than 7 years in low-earth orbit, the cumulative effects of radiation damage are becoming increasingly evident. The result is a continual increase of the hotpixel population and the progressive loss in charge-transfer efficiency (CTE) over time. The decline in CTE has two effects: (1) it reduces the detected source flux as the defects trap charge during readout and (2) it systematically shifts source centroids as the trapped charge is later released. The flux losses can be significant, particularly for faint sources in low background images. In this report, we summarize the radiation damage effects seen in WFC3/UVIS and the evolution of the CTE losses as a function of time, source brightness, and image-background level. In addition, we discuss the available mitigation options, including target placement within the field of view, empirical stellar photometric corrections, post-flash mode and an empirical pixel-based CTE correction. The application of a post-flash has been remarkably effective in WFC3 at reducing CTE losses in low-background images for a relatively small noise penalty. Currently, all WFC3 observers are encouraged to consider post-flash for images with low backgrounds. Finally, a pixel-based CTE correction is available for use after the images have been acquired. Similar to the software in use in the HST Advanced Camera for Surveys (ACS) pipeline, the algorithm employs an observationally-defined model of how much charge is captured and released in order to reconstruct the image. As of Feb 2016, the pixel-based CTE correction is part of the automated WFC3 calibration pipeline. Observers with pre-existing data may request their images from MAST (Mikulski Archive for Space Telescopes) to obtain the improved products.

  12. A Cloud Computing Approach to Personal Risk Management: The Open Hazards Group

    NASA Astrophysics Data System (ADS)

    Graves, W. R.; Holliday, J. R.; Rundle, J. B.

    2010-12-01

    According to the California Earthquake Authority, only about 12% of current California residences are covered by any form of earthquake insurance, down from about 30% in 1996 following the 1994, M6.7 Northridge earthquake. Part of the reason for this decreasing rate of insurance uptake is the high deductible, either 10% or 15% of the value of the structure, and the relatively high cost of the premiums, as much as thousands of dollars per year. The earthquake insurance industry is composed of the CEA, a public-private partnership; modeling companies that produce damage and loss models similar to the FEMA HAZUS model; and financial companies such as the insurance, reinsurance, and investment banking companies in New York, London, the Cayman Islands, Zurich, Dubai, Singapore, and elsewhere. In setting earthquake insurance rates, financial companies rely on models like HAZUS, that calculate on risk and exposure. In California, the process begins with an official earthquake forecast by the Working Group on California Earthquake Probabilities. Modeling companies use these 30 year earthquake probabilities as inputs to their attenuation and damage models to estimate the possible damage factors from scenario earthquakes. Economic loss is then estimated from processes such as structural failure, lost economic activity, demand surge, and fire following the earthquake. Once the potential losses are known, rates can be set so that a target ruin probability of less than 1% or so can be assured. Open Hazards Group was founded with the idea that the global public might be interested in a personal estimate of earthquake risk, computed using data supplied by the public, with models running in a cloud computing environment. These models process data from the ANSS catalog, updated at least daily, to produce rupture forecasts that are backtested with standard Reliability/Attributes and Receiver Operating Characteristic tests, among others. Models for attenuation and structural damage are then used in a computationally efficient workflow to produce real-time estimates of damage and loss for individual structures. All models are based on techniques that either have been published in the literature or will soon be published. Using these results, members of the public can gain an appreciation of their risk of exposure to damage from destructive earthquakes, information that has heretofore only been available to a few members of the financial and insurance industries.

  13. Full-Scale Test and Analysis of a PRSEUS Fuselage Panel to Assess Damage-Containment Features

    NASA Technical Reports Server (NTRS)

    Bergan, Andrew; Bakuckas, John G.; Lovejoy, Andrew E.; Jegley, Dawn C.; Linton, Kim A.; Korkosz, Gregory; Awerbuch, Jonathan; Tan, Tein-Min

    2011-01-01

    Stitched composite technology has the potential to substantially decrease structural weight through enhanced damage containment capabilities. The most recent generation of stitched composite technology, the Pultruded Rod Stitched Efficient Unitized Structure (PRSEUS) concept, has been shown to successfully arrest damage at the sub-component level through tension testing of a three stringer panel with damage in the form of a two-bay notch. In a joint effort undertaken by the National Aeronautics and Space Administration (NASA), the Federal Aviation Administration (FAA), and the Boeing Company, further studies are being conducted to characterize the damage containment features of the PRSEUS concept. A full-scale residual strength test will be performed on a fuselage panel to determine if the load capacity will meet strength, deformation, and damage tolerance requirements. A curved panel was designed, fabricated, and prepared for residual strength testing. A pre-test Finite Element Model (FEM) was developed using design allowables from previous test programs to predict test panel deformation characteristics and margins of safety. Three phases of testing with increasing damage severity include: (1) as manufactured; (2) barely visible impact damage (BVID) and visible impact damage (VID); and (3) discrete source damage (DSD) where the panel will be loaded to catastrophic failure. This paper presents the background information, test plan, and experimental procedure. This paper is the first of several future articles reporting the test preparations, results, and analysis conducted in the test program.

  14. Rapid Multi-Damage Identification for Health Monitoring of Laminated Composites Using Piezoelectric Wafer Sensor Arrays

    PubMed Central

    Si, Liang; Wang, Qian

    2016-01-01

    Through the use of the wave reflection from any damage in a structure, a Hilbert spectral analysis-based rapid multi-damage identification (HSA-RMDI) technique with piezoelectric wafer sensor arrays (PWSA) is developed to monitor and identify the presence, location and severity of damage in carbon fiber composite structures. The capability of the rapid multi-damage identification technique to extract and estimate hidden significant information from the collected data and to provide a high-resolution energy-time spectrum can be employed to successfully interpret the Lamb waves interactions with single/multiple damage. Nevertheless, to accomplish the precise positioning and effective quantification of multiple damage in a composite structure, two functional metrics from the RMDI technique are proposed and used in damage identification, which are the energy density metric and the energy time-phase shift metric. In the designed damage experimental tests, invisible damage to the naked eyes, especially delaminations, were detected in the leftward propagating waves as well as in the selected sensor responses, where the time-phase shift spectra could locate the multiple damage whereas the energy density spectra were used to quantify the multiple damage. The increasing damage was shown to follow a linear trend calculated by the RMDI technique. All damage cases considered showed completely the developed RMDI technique potential as an effective online damage inspection and assessment tool. PMID:27153070

  15. Angular approach combined to mechanical model for tool breakage detection by eddy current sensors

    NASA Astrophysics Data System (ADS)

    Ritou, M.; Garnier, S.; Furet, B.; Hascoet, J. Y.

    2014-02-01

    The paper presents a new complete approach for Tool Condition Monitoring (TCM) in milling. The aim is the early detection of small damages so that catastrophic tool failures are prevented. A versatile in-process monitoring system is introduced for reliability concerns. The tool condition is determined by estimates of the radial eccentricity of the teeth. An adequate criterion is proposed combining mechanical model of milling and angular approach.Then, a new solution is proposed for the estimate of cutting force using eddy current sensors implemented close to spindle nose. Signals are analysed in the angular domain, notably by synchronous averaging technique. Phase shifts induced by changes of machining direction are compensated. Results are compared with cutting forces measured with a dynamometer table.The proposed method is implemented in an industrial case of pocket machining operation. One of the cutting edges has been slightly damaged during the machining, as shown by a direct measurement of the tool. A control chart is established with the estimates of cutter eccentricity obtained during the machining from the eddy current sensors signals. Efficiency and reliability of the method is demonstrated by a successful detection of the damage.

  16. Estimation of average burnup of damaged fuels loaded in Fukushima Dai-ichi reactors by using the {sup 134}Cs/{sup 137}Cs ratio method

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Endo, T.; Sato, S.; Yamamoto, A.

    2012-07-01

    Average burnup of damaged fuels loaded in Fukushima Dai-ichi reactors is estimated, using the {sup 134}Cs/{sup 137}Cs ratio method for measured radioactivities of {sup 134}Cs and {sup 137}Cs in contaminated soils within the range of 100 km from the Fukushima Dai-ichi nuclear power plants. As a result, the measured {sup 134}Cs/{sup 137}Cs ratio from the contaminated soil is 0.996{+-}0.07 as of March 11, 2011. Based on the {sup 134}Cs/{sup 137}Cs ratio method, the estimated burnup of damaged fuels is approximately 17.2{+-}1.5 [GWd/tHM]. It is noted that the numerical results of various calculation codes (SRAC2006/PIJ, SCALE6.0/TRITON, and MVP-BURN) are almost themore » same evaluation values of {sup 134}Cs/ {sup 137}Cs ratio with same evaluated nuclear data library (ENDF-B/VII.0). The void fraction effect in depletion calculation has a major impact on {sup 134}Cs/{sup 137}Cs ratio compared with the differences between JENDL-4.0 and ENDF-B/VII.0. (authors)« less

  17. Pan-European household and industrial water demand: regional relevant estimations

    NASA Astrophysics Data System (ADS)

    Bernhard, Jeroen; Reynaud, Arnaud; de Roo, Ad

    2016-04-01

    Sustainable water management is of high importance to provide adequate quality and quantity of water to European households, industries and agriculture. Especially since demographic, economic and climate changes are expected to increase competition for water between these sectors in the future. A shortage of water implies a reduction in welfare of households or damage to economic sectors. This socio-economic component should be incorporated into the decision-making process when developing water allocation schemes, requiring detailed water use information and cost/benefit functions. We now present the results of our study which is focused at providing regionally relevant pan-European water demand and cost-benefit estimations for the household and industry sector. We gathered consistent data on water consumption, water prices and other relevant variables at the highest spatial detail available from national statistical offices and other organizational bodies. This database provides the most detailed up to date picture of present water use and water prices across Europe. The use of homogeneous data allowed us to compare regions and analyze spatial patterns. We applied econometric methods to determine the main determinants of water demand and make a monetary valuation of water for both the domestic and industry sector. This monetary valuation is important to allow water allocation based on economic damage estimates. We also attempted to estimate how population growth, as well as socio-economic and climatic changes impact future water demand up to 2050 using a homogeneous method for all countries. European projections for the identified major drivers of water demand were used to simulate future conditions. Subsequently, water demand functions were applied to estimate future water use and potential economic damage caused by water shortages. We present our results while also providing some estimation of the uncertainty of our predictions.

  18. A Bayesian Method for Identifying Contaminated Detectors in Low-Level Alpha Spectrometers

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Maclellan, Jay A.; Strom, Daniel J.; Joyce, Kevin E.

    2011-11-02

    Analyses used for radiobioassay and other radiochemical tests are normally designed to meet specified quality objectives, such relative bias, precision, and minimum detectable activity (MDA). In the case of radiobioassay analyses for alpha emitting radionuclides, a major determiner of the process MDA is the instrument background. Alpha spectrometry detectors are often restricted to only a few counts over multi-day periods in order to meet required MDAs for nuclides such as plutonium-239 and americium-241. A detector background criterion is often set empirically based on experience, or frequentist or classical statistics are applied to the calculated background count necessary to meet amore » required MDA. An acceptance criterion for the detector background is set at the multiple of the estimated background standard deviation above the assumed mean that provides an acceptably small probability of observation if the mean and standard deviation estimate are correct. The major problem with this method is that the observed background counts used to estimate the mean, and thereby the standard deviation when a Poisson distribution is assumed, are often in the range of zero to three counts. At those expected count levels it is impossible to obtain a good estimate of the true mean from a single measurement. As an alternative, Bayesian statistical methods allow calculation of the expected detector background count distribution based on historical counts from new, uncontaminated detectors. This distribution can then be used to identify detectors showing an increased probability of contamination. The effect of varying the assumed range of background counts (i.e., the prior probability distribution) from new, uncontaminated detectors will be is discussed.« less

  19. Use of an OSSE to Evaluate Background Error Covariances Estimated by the 'NMC Method'

    NASA Technical Reports Server (NTRS)

    Errico, Ronald M.; Prive, Nikki C.; Gu, Wei

    2014-01-01

    The NMC method has proven utility for prescribing approximate background-error covariances required by variational data assimilation systems. Here, untunedNMCmethod estimates are compared with explicitly determined error covariances produced within an OSSE context by exploiting availability of the true simulated states. Such a comparison provides insights into what kind of rescaling is required to render the NMC method estimates usable. It is shown that rescaling of variances and directional correlation lengths depends greatly on both pressure and latitude. In particular, some scaling coefficients appropriate in the Tropics are the reciprocal of those in the Extratropics. Also, the degree of dynamic balance is grossly overestimated by the NMC method. These results agree with previous examinations of the NMC method which used ensembles as an alternative for estimating background-error statistics.

  20. Deep uncertainty and broad heterogeneity in country-level social cost of carbon

    NASA Astrophysics Data System (ADS)

    Ricke, K.; Drouet, L.; Caldeira, K.; Tavoni, M.

    2017-12-01

    The social cost of carbon (SCC) is a commonly employed metric of the expected economic damages expected from carbon dioxide (CO2) emissions. Recent estimates of SCC range from approximately 10/tonne of CO2 to as much as 1000/tCO2, but these have been computed at the global level. While useful in an optimal policy context, a world-level approach obscures the heterogeneous geography of climate damages and vast differences in country-level contributions to global SCC, as well as climate and socio-economic uncertainties, which are much larger at the regional level. For the first time, we estimate country-level contributions to SCC using recent climate and carbon-cycle model projections, empirical climate-driven economic damage estimations, and information from the Shared Socio-economic Pathways. Central specifications show high global SCC values (median: 417 /tCO2, 66% confidence intervals: 168 - 793 /tCO2) with country-level contributions ranging from -11 (-8 - -14) /tCO2 to 86 (50 - 158) /tCO2. We quantify climate-, scenario- and economic damage- driven uncertainties associated with the calculated values of SCC. We find that while the magnitude of country-level social cost of carbon is highly uncertain, the relative positioning among countries is consistent. Countries incurring large fractions of the global cost include India, China, and the United States. The share of SCC distributed among countries is robust, indicating climate change winners and losers from a geopolitical perspective.

  1. Estimation of Confined Peak Strength of Crack-Damaged Rocks

    NASA Astrophysics Data System (ADS)

    Bahrani, Navid; Kaiser, Peter K.

    2017-02-01

    It is known that the unconfined compressive strength of rock decreases with increasing density of geological features such as micro-cracks, fractures, and veins both at the laboratory specimen and rock block scales. This article deals with the confined peak strength of laboratory-scale rock specimens containing grain-scale strength dominating features such as micro-cracks. A grain-based distinct element model, whereby the rock is simulated with grains that are allowed to deform and break, is used to investigate the influence of the density of cracks on the rock strength under unconfined and confined conditions. A grain-based specimen calibrated to the unconfined and confined strengths of intact and heat-treated Wombeyan marble is used to simulate rock specimens with varying crack densities. It is demonstrated how such cracks affect the peak strength, stress-strain curve and failure mode with increasing confinement. The results of numerical simulations in terms of unconfined and confined peak strengths are used to develop semi-empirical relations that relate the difference in strength between the intact and crack-damaged rocks to the confining pressure. It is shown how these relations can be used to estimate the confined peak strength of a rock with micro-cracks when the unconfined and confined strengths of the intact rock and the unconfined strength of the crack-damaged rock are known. This approach for estimating the confined strength of crack-damaged rock specimens, called strength degradation approach, is then verified by application to published laboratory triaxial test data.

  2. Evaluation of spatial and temporal patterns of insect damage and aflatoxin level in the pre-harvest corn fields to improve management tactics.

    PubMed

    Ni, Xinzhi; Wilson, Jeffrey P; Toews, Michael D; Buntin, G David; Lee, R Dewey; Li, Xin; Lei, Zhongren; He, Kanglai; Xu, Wenwei; Li, Xianchun; Huffaker, Alisa; Schmelz, Eric A

    2014-10-01

    Spatial and temporal patterns of insect damage in relation to aflatoxin contamination in a corn field with plants of uniform genetic background are not well understood. After previous examination of spatial patterns of insect damage and aflatoxin in pre-harvest corn fields, we further examined both spatial and temporal patterns of cob- and kernel-feeding insect damage, and aflatoxin level with two samplings at pre-harvest in 2008 and 2009. The feeding damage by each of the ear/kernel-feeding insects (i.e., corn earworm/fall armyworm damage on the silk/cob, and discoloration of corn kernels by stink bugs) and maize weevil population were assessed at each grid point with five ears. Sampling data showed a field edge effect in both insect damage and aflatoxin contamination in both years. Maize weevils tended toward an aggregated distribution more frequently than either corn earworm or stink bug damage in both years. The frequency of detecting aggregated distribution for aflatoxin level was less than any of the insect damage assessments. Stink bug damage and maize weevil number were more closely associated with aflatoxin level than was corn earworm damage. In addition, the indices of spatial-temporal association (χ) demonstrated that the number of maize weevils was associated between the first (4 weeks pre-harvest) and second (1 week pre-harvest) samplings in both years on all fields. In contrast, corn earworm damage between the first and second samplings from the field on the Belflower Farm, and aflatoxin level and corn earworm damage from the field on the Lang Farm were dissociated in 2009. Published 2012. This article is a U.S. Government work and is in the public domain in the USA.

  3. Global transport and deposition of 137Cs following the Fukushima nuclear power plant accident in Japan: emphasis on Europe and Asia using high-resolution model versions and radiological impact assessment of the human population and the environment using interactive tools.

    PubMed

    Evangeliou, Nikolaos; Balkanski, Yves; Cozic, Anne; Møller, Anders Pape

    2013-06-04

    The earthquake and the subsequent tsunami that occurred offshore of Japan resulted in an important loss of life and a serious accident at the nuclear facility of Fukushima. The "hot spots" of the release are evaluated here applying the model LMDZORINCA for (137)Cs. Moreover, an assessment is attempted for the population and the environment using the dosimetric scheme of the WHO and the interactive tool ERICA, respectively. Cesium-137 was deposited mostly in Pacific and Atlantic Oceans and North Pole (80%), whereas the rest in the continental areas of North America and Eurasia contributed slightly to the natural background (0.5-5.0 kBq m(-2)). The effective dose from (137)Cs and (134)Cs (radiocesium) irradiation during the first 3 months was estimated between 1-5 mSv in Fukushima and the neighboring prefectures. In the rest of Japan, the respective doses were found to be less than 0.5 mSv, whereas in the rest of the world it was less than 0.1 mSv. Such doses are equivalent with the obtained dose from a simple X-ray; for the highly contaminated regions, they are close to the dose limit for exposure due to radon inhalation (10 mSv). The calculated dose rates from radiocesium exposure on reference organisms ranged from 0.03 to 0.18 μGy h(-1), which are 2 orders of magnitude below the screening dose limit (10 μGy h(-1)) that could result in obvious effects on the population. However, these results may underestimate the real situation, since stable soil density was used in the calculations, a zero radiocesium background was assumed, and dose only from two radionuclides was estimated, while more that 40 radionuclides have been deposited in the vicinity of the facility. When monitoring data applied, much higher dose rates were estimated certifying ecological risk for small mammals and reptiles in terms of cytogenetic damage and reproduction.

  4. A Multi-temporal Analysis of Logging Impacts on Tropical Forest Structure Using Airborne Lidar Data

    NASA Astrophysics Data System (ADS)

    Keller, M. M.; Pinagé, E. R.; Duffy, P.; Longo, M.; dos-Santos, M. N.; Leitold, V.; Morton, D. C.

    2017-12-01

    The long-term impacts of selective logging on carbon cycling and ecosystem function in tropical-forests are still uncertain. Despite improvements in selective logging detection using satellite data, quantifying changes in forest structure from logging and recovery following logging is difficult using orbital data. We analyzed the dynamics of forest structure comparing logged and unlogged forests in the Eastern Brazilian Amazon (Paragominas Municipality, Pará State) using small footprint discrete return airborne lidar data acquired in 2012 and 2014. Logging operations were conducted at the 1200 ha study site from 2006 through 2013 using reduced impact logging techniques—management practices that minimize canopy and ground damage compared to more common conventional logging. Nevertheless, logging still reduced aboveground biomass by 10% to 20% in logged areas compared to intact forests. We aggregated lidar point-cloud data at spatial scales ranging from 50 m to 250 m and developed a binomial classification model based on the height distribution of lidar returns in 2012 and validated the model against the 2014 lidar acquisition. We accurately classified intact and logged forest classes compared with field data. Classification performance improved as spatial resolution increased (AUC = 0.974 at 250 m). We analyzed the differences in canopy gaps, understory damage (based on a relative density model), and biomass (estimated from total canopy height) of intact and logged classes. As expected, logging greatly increased both canopy gap formation and understory damage. However, while the area identified as canopy gap persisted for at least 8 years (from the oldest logging treatments in 2006 to the most recent lidar acquisition in 2014), the effects of ground damage were mostly erased by vigorous understory regrowth after about 5 years. The rate of new gap formation was 6 to 7 times greater in recently logged forests compared to undisturbed forests. New gaps opened at a rate of 1.8 times greater than background even 8 years following logging demonstrating the occurrence of delayed tree mortality. Our study showed that even low-intensity anthropogenic disturbances can cause persistent changes in tropical forest structure and dynamics.

  5. The Physiological Bases of Hidden Noise-Induced Hearing Loss: Protocol for a Functional Neuroimaging Study

    PubMed Central

    Hall, Deborah A; Guest, Hannah; Prendergast, Garreth; Plack, Christopher J; Francis, Susan T

    2018-01-01

    Background Rodent studies indicate that noise exposure can cause permanent damage to synapses between inner hair cells and high-threshold auditory nerve fibers, without permanently altering threshold sensitivity. These demonstrations of what is commonly known as hidden hearing loss have been confirmed in several rodent species, but the implications for human hearing are unclear. Objective Our Medical Research Council–funded program aims to address this unanswered question, by investigating functional consequences of the damage to the human peripheral and central auditory nervous system that results from cumulative lifetime noise exposure. Behavioral and neuroimaging techniques are being used in a series of parallel studies aimed at detecting hidden hearing loss in humans. The planned neuroimaging study aims to (1) identify central auditory biomarkers associated with hidden hearing loss; (2) investigate whether there are any additive contributions from tinnitus or diminished sound tolerance, which are often comorbid with hearing problems; and (3) explore the relation between subcortical functional magnetic resonance imaging (fMRI) measures and the auditory brainstem response (ABR). Methods Individuals aged 25 to 40 years with pure tone hearing thresholds ≤20 dB hearing level over the range 500 Hz to 8 kHz and no contraindications for MRI or signs of ear disease will be recruited into the study. Lifetime noise exposure will be estimated using an in-depth structured interview. Auditory responses throughout the central auditory system will be recorded using ABR and fMRI. Analyses will focus predominantly on correlations between lifetime noise exposure and auditory response characteristics. Results This paper reports the study protocol. The funding was awarded in July 2013. Enrollment for the study described in this protocol commenced in February 2017 and was completed in December 2017. Results are expected in 2018. Conclusions This challenging and comprehensive study will have the potential to impact diagnostic procedures for hidden hearing loss, enabling early identification of noise-induced auditory damage via the detection of changes in central auditory processing. Consequently, this will generate the opportunity to give personalized advice regarding provision of ear defense and monitoring of further damage, thus reducing the incidence of noise-induced hearing loss. PMID:29523503

  6. Detection of Non-Symmetrical Damage in Smart Plate-Like Structures

    NASA Technical Reports Server (NTRS)

    Blanks, H. T.; Emeric, P. R.

    1998-01-01

    A two-dimensional model for in-plane vibrations of a cantilever plate with a non-symmetrical damage is used in the context of defect identification in materials with piezoelectric ceramic patches bonded to their surface. These patches can act both as actuators and sensors in a self-analyzing fashion, which is a characteristic of smart materials. A Galerkin method is used to approximate the dynamic response of these structures. The natural frequency shifts due to the damage are estimated numerically and compared to experimental data obtained from tests on cantilever aluminum plate-like structures damaged at different locations with defects of different depths. The damage location and extent are determined by an enhanced least square identification method. Efficacy of the frequency shift based algorithms is demonstrated using experimental data.

  7. Aerodynamic Effects and Modeling of Damage to Transport Aircraft

    NASA Technical Reports Server (NTRS)

    Shah, Gautam H.

    2008-01-01

    A wind tunnel investigation was conducted to measure the aerodynamic effects of damage to lifting and stability/control surfaces of a commercial transport aircraft configuration. The modeling of such effects is necessary for the development of flight control systems to recover aircraft from adverse, damage-related loss-of-control events, as well as for the estimation of aerodynamic characteristics from flight data under such conditions. Damage in the form of partial or total loss of area was applied to the wing, horizontal tail, and vertical tail. Aerodynamic stability and control implications of damage to each surface are presented, to aid in the identification of potential boundaries in recoverable stability or control degradation. The aerodynamic modeling issues raised by the wind tunnel results are discussed, particularly the additional modeling requirements necessitated by asymmetries due to damage, and the potential benefits of such expanded modeling.

  8. Depth estimation of multi-layered impact damage in PMC using lateral thermography

    NASA Astrophysics Data System (ADS)

    Whitlow, Travis; Kramb, Victoria; Reibel, Rick; Dierken, Josiah

    2018-04-01

    Characterization of impact damage in polymer matrix composites (PMCs) continues to be a challenge due to the complex internal structure of the material. Nondestructive characterization approaches such as normal incident immersion ultrasound and flash thermography are sensitive to delamination damage, but do not provide information regarding damage obscured by the delaminations. Characterization of material state below a delamination requires a technique which is sensitive to in-plane damage modes such as matrix cracking and fiber breakage. Previous studies of the lateral heat flow through a composite laminate showed that the diffusion time was sensitive to the depth of the simulated damage zone. The current study will further evaluate the lateral diffusion model to provide sensitivity limits for the modeled flaw dimensions. Comparisons between the model simulations and experimental data obtained using a concentrated heat source and machined targets will also be presented.

  9. Nondestructive monitoring damage in composites using scanning laser acoustic microscopy

    NASA Technical Reports Server (NTRS)

    Wey, A. C.; Kessler, L. W.; Dos Reis, H. L. M.

    1992-01-01

    Several Nicalon fiber reinforced LAS (lithium alumino-silicate) glass matrix composites were tested to study the relation between the residual strength and the different amounts of damage. The samples were fatigued by four-point cyclic loading at a 5 Hz rate at 500 C for a different number of cycles. 10 MHz scanning laser acoustic microscope (SLAM) images were taken to monitor damage on the samples. Our SLAM results indicate that there were defects already existing throughout the sample before fatigue, and the resultant damage pattern from fatigue could be related to the initial defect distribution in the sample. Finally, the fatigued samples were fractured and the residual strength data could not be explained by the cyclic fatigue alone. Rather, the damage patterns evident in the SLAM images were needed to explain the scatter in the data. The results show that SLAM is useful in nondestructively monitoring damage and estimating residual strength of fatigued ceramic composites.

  10. Numerical and experimental investigations on cavitation erosion

    NASA Astrophysics Data System (ADS)

    Fortes Patella, R.; Archer, A.; Flageul, C.

    2012-11-01

    A method is proposed to predict cavitation damage from cavitating flow simulations. For this purpose, a numerical process coupling cavitating flow simulations and erosion models was developed and applied to a two-dimensional (2D) hydrofoil tested at TUD (Darmstadt University of Technology, Germany) [1] and to a NACA 65012 tested at LMH-EPFL (Lausanne Polytechnic School) [2]. Cavitation erosion tests (pitting tests) were carried out and a 3D laser profilometry was used to analyze surfaces damaged by cavitation [3]. The method allows evaluating the pit characteristics, and mainly the volume damage rates. The paper describes the developed erosion model, the technique of cavitation damage measurement and presents some comparisons between experimental results and numerical damage predictions. The extent of cavitation erosion was correctly estimated in both hydrofoil geometries. The simulated qualitative influence of flow velocity, sigma value and gas content on cavitation damage agreed well with experimental observations.

  11. Skin damage associated with intravenous therapy: common problems and strategies for prevention.

    PubMed

    Thayer, Debra

    2012-01-01

    Infusion therapy is among the most common health care interventions, with approximately 90% of hospitalized patients receiving vascular access and an estimated 1.3 million home infusion therapies delivered annually. Whereas most individuals complete their therapy uneventfully, others experience alterations in skin integrity, some significant enough to disrupt therapy. There are limited published data on the incidence of skin damage associated with infusion therapy, and the etiology of damage has not been previously described in detail. Wound, ostomy, and continence (WOC) nurses have developed a significant understanding of skin-related problems and effective prevention strategies from over 40 years of experience with ostomy patients--another population in which adhesive wear is a constant and localized, superficial skin damage is common. This article will offer a WOC nursing perspective of skin damage and seek to provide a context for understanding and preventing skin damage in the infusion therapy patient.

  12. Protective role of Scoparia dulcis plant extract on brain antioxidant status and lipidperoxidation in STZ diabetic male Wistar rats

    PubMed Central

    Pari, Leelavinothan; Latha, Muniappan

    2004-01-01

    Background The aim of the study was to investigate the effect of aqueous extract of Scoparia dulcis on the occurrence of oxidative stress in the brain of rats during diabetes by measuring the extent of oxidative damage as well as the status of the antioxidant defense system. Methods Aqueous extract of Scoparia dulcis plant was administered orally (200 mg/kg body weight) and the effect of extract on blood glucose, plasma insulin and the levels of thiobarbituric acid reactive substances (TBARS), hydroperoxides, superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx), glutathione-S-transferase (GST) and reduced glutathione (GSH) were estimated in streptozotocin (STZ) induced diabetic rats. Glibenclamide was used as standard reference drug. Results A significant increase in the activities of plasma insulin, superoxide dismutase, catalase, glutathione peroxidase, glutathione-S-transferase and reduced glutathione was observed in brain on treatment with 200 mg/kg body weight of Scoparia dulcis plant extract (SPEt) and glibenclamide for 6 weeks. Both the treated groups showed significant decrease in TBARS and hydroperoxides formation in brain, suggesting its role in protection against lipidperoxidation induced membrane damage. Conclusions Since the study of induction of the antioxidant enzymes is considered to be a reliable marker for evaluating the antiperoxidative efficacy of the medicinal plant, these findings suggest a possible antiperoxidative role for Scoparia dulcis plant extract. Hence, in addition to antidiabetic effect, Scoparia dulcis possess antioxidant potential that may be used for therapeutic purposes. PMID:15522116

  13. Elevated Frequencies of Micronuclei and other Nuclear Abnormalities of Chrome Plating Workers Occupationally Exposed to Hexavalent Chromium

    PubMed Central

    Sudha, S; Kripa, SK; Shibily, P; Shyn, J

    2011-01-01

    Background Biomonitoring provides a useful tool to estimate the genetic risk from exposure to genotoxic agents. The aim of this study was to assess the potential cytogenetic damage associated with occupational exposure to hexavalent chromium by using micronuclei (MN) as a biomarker. Methods This was a cross-sectional study and all participants were males. Both the exposed and control individuals were selected from Coimbatore, Southern India. Exfoliated buccal cells from 44 chrome plating workers and 40 age and sex matched control subjects were examined for MN frequency and nuclear abnormalities (NA) other than micronuclei, such as binucleates, broken eggs, karyorrhexis, karyolysis and pyknosis. Results Results showed statistically significant difference between chrome plating workers and control groups. MN and NA frequencies in chrome plating workers were significantly higher than those in control groups (p < 0.05) and also significantly related to smoking habit (P < 0.05). A significant difference in NA was observed in workers exposed to chromium for longer duration. In addition to this, a higher degree of NA was observed among smokers. Conclusion MN and other NA reflect genetic changes, events associated with carcinogenesis. Therefore the results of this study indicate that chrome plating workers are under risk of significant cytogenetic damage. Therefore, there is a need to educate those who work with heavy metals about the potential hazard of occupational exposure and the importance of using protective measures. PMID:26328050

  14. 48 CFR 1816.405-274 - Award fee evaluation factors.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... omission by the contractor that results in compromise of classified information, illegal technology... information technology services, equipment or property damage from vandalism greater than $250,000, or theft... negotiated estimated cost of the contract. This estimated cost may include the value of undefinitized change...

  15. 48 CFR 1816.405-274 - Award fee evaluation factors.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... omission by the contractor that results in compromise of classified information, illegal technology... information technology services, equipment or property damage from vandalism greater than $250,000, or theft... negotiated estimated cost of the contract. This estimated cost may include the value of undefinitized change...

  16. 48 CFR 1816.405-274 - Award fee evaluation factors.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... omission by the contractor that results in compromise of classified information, illegal technology... information technology services, equipment or property damage from vandalism greater than $250,000, or theft... negotiated estimated cost of the contract. This estimated cost may include the value of undefinitized change...

  17. 43 CFR 11.84 - Damage determination phase-implementation guidance.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... expected present value of the costs of restoration, rehabilitation, replacement, and/or acquisition of... be estimated in the form of an expected present value dollar amount. In order to perform this... estimate is the expected present value of uses obtained through restoration, rehabilitation, replacement...

  18. 43 CFR 11.84 - Damage determination phase-implementation guidance.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... expected present value of the costs of restoration, rehabilitation, replacement, and/or acquisition of... be estimated in the form of an expected present value dollar amount. In order to perform this... estimate is the expected present value of uses obtained through restoration, rehabilitation, replacement...

  19. 43 CFR 11.84 - Damage determination phase-implementation guidance.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... expected present value of the costs of restoration, rehabilitation, replacement, and/or acquisition of... be estimated in the form of an expected present value dollar amount. In order to perform this... estimate is the expected present value of uses obtained through restoration, rehabilitation, replacement...

  20. Meniscus Induced Cartilaginous Damage and Non-linear Gross Anatomical Progression of Early-stage Osteoarthritis in a Canine Model

    PubMed Central

    Kahn, David; Mittelstaedt, Daniel; Matyas, John; Qu, Xiangui; Lee, Ji Hyun; Badar, Farid; Les, Clifford; Zhuang, Zhiguo; Xia, Yang

    2016-01-01

    Background: The predictable outcome of the anterior cruciate ligament transection (ACLT) canine model, and the similarity to naturally occurring osteoarthritis (OA) in humans, provide a translatable method for studying OA. Still, evidence of direct meniscus-induced cartilaginous damage has not been identified, and gross-anatomical blinded scoring of early-stage OA has not been performed. Objective: A gross anatomical observation and statistical analysis of OA progression to determine meniscus induced cartilaginous damage, to measure the macroscopic progression of OA, and to address matters involving arthroscopic and surgical procedures of the knee. Method: Unblinded assessment and blinded scoring of meniscal, tibial, femoral, and patellar damage were performed for control and at four time points following unilateral ACLT: 3-week (N=4), 8-week (N=4), 12-week (N=5), and 25-week (N=4). Mixed-model statistics illustrates damage (score) progression; Wilcoxon rank-sum tests compared time-point scores; and Wilcoxon signed-rank tests compared ACLT and contralateral scores, and meniscus and tibia scores. Result: Damage was manifest first on the posterior aspect of the medial meniscus and subsequently on the tibia and femur, implying meniscal damage can precede, coincide with, and aggravate cartilage damage. Damage extent varied chronologically and was dependent upon the joint component. Meniscal damage was evident at 3 weeks and progressed through 25-weeks. Meniscal loose bodies corresponded to tibial cartilage damage location and extent through 12 weeks, followed by cartilage repair activity after complete meniscal degeneration. Conclusion: This study provides additional information for understanding OA progression, identifying OA biomarkers, and arthroscopic and meniscectomy procedures. PMID:28144379

  1. Urban Earthquake Shaking and Loss Assessment

    NASA Astrophysics Data System (ADS)

    Hancilar, U.; Tuzun, C.; Yenidogan, C.; Zulfikar, C.; Durukal, E.; Erdik, M.

    2009-04-01

    This study, conducted under the JRA-3 component of the EU NERIES Project, develops a methodology and software (ELER) for the rapid estimation of earthquake shaking and losses the Euro-Mediterranean region. This multi-level methodology developed together with researchers from Imperial College, NORSAR and ETH-Zurich is capable of incorporating regional variability and sources of uncertainty stemming from ground motion predictions, fault finiteness, site modifications, inventory of physical and social elements subjected to earthquake hazard and the associated vulnerability relationships. GRM Risk Management, Inc. of Istanbul serves as sub-contractor tor the coding of the ELER software. The methodology encompasses the following general steps: 1. Finding of the most likely location of the source of the earthquake using regional seismotectonic data base and basic source parameters, and if and when possible, by the estimation of fault rupture parameters from rapid inversion of data from on-line stations. 2. Estimation of the spatial distribution of selected ground motion parameters through region specific ground motion attenuation relationships and using shear wave velocity distributions.(Shake Mapping) 4. Incorporation of strong ground motion and other empirical macroseismic data for the improvement of Shake Map 5. Estimation of the losses (damage, casualty and economic) at different levels of sophistication (0, 1 and 2) that commensurate with the availability of inventory of human built environment (Loss Mapping) Level 2 analysis of the ELER Software (similar to HAZUS and SELENA) is essentially intended for earthquake risk assessment (building damage, consequential human casualties and macro economic loss quantifiers) in urban areas. The basic Shake Mapping is similar to the Level 0 and Level 1 analysis however, options are available for more sophisticated treatment of site response through externally entered data and improvement of the shake map through incorporation of accelerometric and other macroseismic data (similar to the USGS ShakeMap System). The building inventory data for the Level 2 analysis will consist of grid (geo-cell) based urban building and demographic inventories. For building grouping the European building typology developed within the EU-FP5 RISK-EU project is used. The building vulnerability/fragility relationships to be used can be user selected from a list of applicable relationships developed on the basis of a comprehensive study, Both empirical and analytical relationships (based on the Coefficient Method, Equivalent Linearization Method and the Reduction Factor Method of analysis) can be employed. Casualties in Level 2 analysis are estimated based on the number of buildings in different damaged states and the casualty rates for each building type and damage level. Modifications to the casualty rates can be used if necessary. ELER Level 2 analysis will include calculation of direct monetary losses as a result building damage that will allow for repair-cost estimations and specific investigations associated with earthquake insurance applications (PML and AAL estimations). ELER Level 2 analysis loss results obtained for Istanbul for a scenario earthquake using different techniques will be presented with comparisons using different earthquake damage assessment software. The urban earthquake shaking and loss information is intented for dissemination in a timely manner to related agencies for the planning and coordination of the post-earthquake emergency response. However the same software can also be used for scenario earthquake loss estimation, related Monte-Carlo type simulations and eathquake insurance applications.

  2. KSC-08pd2431

    NASA Image and Video Library

    2008-08-21

    CAPE CANAVERAL, Fla. – Due to Tropical Storm Fay, the roadside canals and surrounding grounds are flooded at NASA's Kennedy Space Center. In the background is the Vehicle Assembly Building. The storm passed over the center Aug. 20 and then stalled offshore, bringing with it heavy rain and tropical storm force wind. Kennedy closed Aug. 19 because of Fay and reopened for normal operations Aug. 22. Based on initial assessments, there was no damage to space flight hardware, such as the space shuttles and Hubble Space Telescope equipment. Some facilities did sustain minor damage. Photo credit: NASA/Ben Smegelsky

  3. Electronic quantization in dielectric nanolaminates

    NASA Astrophysics Data System (ADS)

    Willemsen, T.; Geerke, P.; Jupé, M.; Gallais, L.; Ristau, D.

    2016-12-01

    The scientific background in the field of the laser induced damage processes in optical coatings has been significantly extended during the last decades. Especially for the ultra-short pulse regime a clear correlation between the electronic material parameters and the laser damage threshold could be demonstrated. In the present study, the quantization in nanolaminates is investigated to gain a deeper insight into the behavior of the blue shift of the bandgap in specific coating materials as well as to find approximations for the effective mass of the electrons. The theoretical predictions are correlated to the measurements.

  4. Air pollution and health implications of regional electricity transfer at generational centre and design of compensation mechanism

    NASA Astrophysics Data System (ADS)

    Relhan, Nemika

    India's electricity generation is primarily from coal. As a result of interconnection of grid and establishment of pithead power plants, there has been increased electricity transfer from one region to the other. This results in imbalance of pollution loads between the communities located in generation vis-a-vis consumption region. There may be some states, which are major power generation centres and hence are facing excessive environmental degradation. On the other hand, electricity importing regions are reaping the benefits without paying proper charges for it because present tariff structure does not include the full externalities in it. The present study investigates the distributional implications in terms of air pollution loads between the electricity generation and consumption regions at the state level. It identifies the major electricity importing and exporting states in India. Next, as a case study, it estimates the health damage as a result of air pollution from thermal power plants (TPPs) located in a critically polluted region that is one of the major generator and exporter of electricity. The methodology used to estimate the health damage is based on impact pathway approach. In this method, air pollution modelling has been performed in order to estimate the gridded Particulate Matter (PM) concentration at various receptor locations in the study domain. The air quality modeling exercise helps to quantify the air pollution concentration in each grid and also apportion the contribution of power plants to the total concentration. The health impacts as a result of PM have been estimated in terms of number of mortality and morbidity cases using Concentration Response Function (CRF's) available in the literature. Mortality has been converted into Years of Life Lost (YOLL) using life expectancy table and age wise death distribution. Morbidity has been estimated in terms of number of cases with respect to various health end points. To convert this health damage into economic loss, the YOLL has been multiplied with Value of Life Year Lost (VOLY). VOLY has been derived from two approaches namely, the Gross Domestic Product (GDP) per capita i.e. using human capital approach and Value of Statistical Life (VOSL) i.e. using Willingness to Pay (WTP) approach derived from Indian revealed preference study. The morbidity damage has been estimated using cost of illness values available in the literature. A range of result has been presented depending on the CRF's used to estimates YOLL and morbidity and the values used to convert these health damages into monetary estimates. The study further suggests a broad framework of compensatory mechanism that includes 1) amount of compensation to be paid 2) mechanism to collect the compensation fund and 3) mechanism to compensate the affected communities. Both, curative and mitigative measures to protect the communities from the pollution generated in the power exporting region have been suggested.

  5. C2-C6 background hydrocarbon concentrations monitored at a roof top and green park site, in Dublin City centre.

    PubMed

    O'Donoghue, R T; Broderick, B M

    2007-09-01

    A 5 week monitoring campaign was carried out in Dublin City centre, to establish which site gave a more accurate background city centre estimation: a roof-top or green field site. This background represented a conservative estimate of HC exposure in Dublin City centre, useful for quantifying health effects related to this form of pollution and also for establishing a local background relative to the four surrounding main roads when the wind direction is travelling towards each road with the background receptor upwind. Over the entire monitoring campaign, the lowest concentrations and relative standard deviations were observed at the green field site, regardless of time of day or meteorological effects.

  6. FOLATE DEFICIENCY ENHANCES ARSENIC-INDUCED GENOTOXICITY IN MICE

    EPA Science Inventory

    Folate deficiency increases background levels of DNA damage and can enhance the mutagenicity of chemical agents. Duplicate experiments were performed to investigate the effect of dietary folate deficiency on arsenic induction of micronuclei (MN) in peripheral blood cells. Male C5...

  7. DIETARY FOLATE DEFICIENCY ENHANCES ARSENIC-INDUCED MICRONUCLEUS FORMATION IN MICE

    EPA Science Inventory


    Dietary folate deficiency enhances arsenic-induced micronucleus formation in mice.

    Folate deficiency increases background levels ofDNA damage and can enhance the mutagenicity of chemical agents. Duplicate experiments were performed to investigate the effect of dietary...

  8. A new method to assess damage to RCMRFs from period elongation and Park-Ang damage index using IDA

    NASA Astrophysics Data System (ADS)

    Aghagholizadeh, Mehrdad; Massumi, Ali

    2016-09-01

    Despite a significant progress in loading and design codes of seismic resistant structures and technology improvements in building structures, the field of civil engineering is still facing critical challenges. An example of those challenges is the assessment of the state of damage that has been imposed to a structure after earthquakes of different intensities. To determine the operability of a structure and its resistance to probable future earthquakes, quick assessment of damages and determining the operability of a structure after an earthquake are crucial. Present methods to calculate damage to structures are time consuming and do not accurately provide the rate of damage. Damage estimation is important task in the fields of structural health monitoring and decision-making. This study examines the relationship between period elongation and the Park-Ang damage index. A dynamic non-linear analysis is employed with IDARC program to calculate the amount of damage and period of the current state. This new method is shown to be a quick and accurate technique for damage assessment. It is easy to calculate the period of an existing structure and changes in the period which reflects changes in the stiffness matrix.

  9. Photutils: Photometry tools

    NASA Astrophysics Data System (ADS)

    Bradley, Larry; Sipocz, Brigitta; Robitaille, Thomas; Tollerud, Erik; Deil, Christoph; Vinícius, Zè; Barbary, Kyle; Günther, Hans Moritz; Bostroem, Azalee; Droettboom, Michael; Bray, Erik; Bratholm, Lars Andersen; Pickering, T. E.; Craig, Matt; Pascual, Sergio; Greco, Johnny; Donath, Axel; Kerzendorf, Wolfgang; Littlefair, Stuart; Barentsen, Geert; D'Eugenio, Francesco; Weaver, Benjamin Alan

    2016-09-01

    Photutils provides tools for detecting and performing photometry of astronomical sources. It can estimate the background and background rms in astronomical images, detect sources in astronomical images, estimate morphological parameters of those sources (e.g., centroid and shape parameters), and perform aperture and PSF photometry. Written in Python, it is an affiliated package of Astropy (ascl:1304.002).

  10. Structural Vulnerability of the Boeing B-29 Aircraft Wing to Damage by Warhead Fragments

    NASA Technical Reports Server (NTRS)

    Kordes, Eldon E.; OSullivan, William J., Jr.

    1952-01-01

    An elementary type of analysis has been used to determine the amount of wing tip that must be severed to produce irrevocable loss of control of a B-29 airplane. The remaining inboard structure of the Boeing B-29 wing has then been analyzed and curves are presented for the estimated reduction in structural strength due to four general types of damage produced by rod-type warhead fragments. The curves indicate the extent of structural damage required to produce a kill of the aircraft within 10 seconds.

  11. The use of the DInSAR method in the monitoring of road damage caused by mining activities

    NASA Astrophysics Data System (ADS)

    Murdzek, Radosław; Malik, Hubert; Leśniak, Andrzej

    2018-04-01

    This paper reviews existing remote sensing methods of road damage detection and demonstrates the possibility of using DInSAR (Differential Interferometry SAR) method to identify endangered road sections. In this study two radar images collected by Sentinel-1 satellite have been used. Images were acquired with 24 days interval in 2015. The analysis allowed to estimate the scale of the post-mining deformation that occurred in Upper Silesia and to indicate areas where road infrastructure is particularly vulnerable to damage.

  12. Economic costs of extratropical storms under climate change: An application of FUND

    NASA Astrophysics Data System (ADS)

    Narita, D.; Tol, R.; Anthoff, D.

    2009-12-01

    Extratropical cyclones have attracted some attention in climate policy circles as a possible significant damage factor of climate change. This study conducts an assessment of economic impacts of increased storm activities under climate change with the integrated assessment model FUND 3.5. FUND is a model that calculates damages of climate change for 16 regions by making use of exogenous scenarios of socioeconomic variables (for details of our estimation approach, see our working paper whose URL is indicated below). Our estimation shows that in the base case, the direct economic damage of enhanced storms due to climate change amounts to $2.8 billion globally (approximately 38% of the total economic loss of storms at present) at the year 2100, while the ratio to the world GDP is 0.0009%. The regional results (Figure 1) indicate that the economic effect of extratropical storms with climate change would have relatively minor importance for the US (USA): The enhanced extratropical storm damage (less than 0.001% of GDP for the base case) is one order of magnitude lower than the tropical cyclone damage (roughly 0.01% GDP) calculated by the same version of FUND. In the regions without strong tropical cyclone influence, such as Western Europe (WEU) and Australia and New Zealand (ANZ), the extratropical storms might have some more significance as a possible damage factor of climate change. Especially for the latter, the direct economic damage could amount to more than 0.006% of GDP. Still, the impact is small relative to the income growth expected in these regions. Figure 1. Increased direct economic loss at the year 2100 for selected regions (results are shown for the three different baselines: the years 1986-2005, 1976-2005, and 1996-2005). US - USA; Canada - CAN; Western Europe - WEU; Australia and New Zealand - ANZ.

  13. Optimal Search for an Astrophysical Gravitational-Wave Background

    NASA Astrophysics Data System (ADS)

    Smith, Rory; Thrane, Eric

    2018-04-01

    Roughly every 2-10 min, a pair of stellar-mass black holes merge somewhere in the Universe. A small fraction of these mergers are detected as individually resolvable gravitational-wave events by advanced detectors such as LIGO and Virgo. The rest contribute to a stochastic background. We derive the statistically optimal search strategy (producing minimum credible intervals) for a background of unresolved binaries. Our method applies Bayesian parameter estimation to all available data. Using Monte Carlo simulations, we demonstrate that the search is both "safe" and effective: it is not fooled by instrumental artifacts such as glitches and it recovers simulated stochastic signals without bias. Given realistic assumptions, we estimate that the search can detect the binary black hole background with about 1 day of design sensitivity data versus ≈40 months using the traditional cross-correlation search. This framework independently constrains the merger rate and black hole mass distribution, breaking a degeneracy present in the cross-correlation approach. The search provides a unified framework for population studies of compact binaries, which is cast in terms of hyperparameter estimation. We discuss a number of extensions and generalizations, including application to other sources (such as binary neutron stars and continuous-wave sources), simultaneous estimation of a continuous Gaussian background, and applications to pulsar timing.

  14. Dynamic deformations and the M6.7, Northridge, California earthquake

    USGS Publications Warehouse

    Gomberg, J.

    1997-01-01

    A method of estimating the complete time-varying dynamic formation field from commonly available three-component single station seismic data has been developed and applied to study the relationship between dynamic deformation and ground failures and structural damage using observations from the 1994 Northridge, California earthquake. Estimates from throughout the epicentral region indicate that the horizontal strains exceed the vertical ones by more than a factor of two. The largest strains (exceeding ???100 ??strain) correlate with regions of greatest ground failure. There is a poor correlation between structural damage and peak strain amplitudes. The smallest strains, ???35 ??strain, are estimated in regions of no damage or ground failure. Estimates in the two regions with most severe and well mapped permanent deformation, Potrero Canyon and the Granada-Mission Hills regions, exhibit the largest strains; peak horizontal strains estimates in these regions equal ???139 and ???229 ??strain respectively. Of note, the dynamic principal strain axes have strikes consistent with the permanent failure features suggesting that, while gravity, sub-surface materials, and hydrologic conditions undoubtedly played fundamental roles in determining where and what types of failures occurred, the dynamic deformation field may have been favorably sized and oriented to initiate failure processes. These results support other studies that conclude that the permanent deformation resulted from ground shaking, rather than from static strains associated with primary or secondary faulting. They also suggest that such an analysis, either using data or theoretical calculations, may enable observations of paleo-ground failure to be used as quantitative constraints on the size and geometry of previous earthquakes. ?? 1997 Elsevier Science Limited.

  15. Raman study of radiation-damaged zircon under hydrostatic compression

    NASA Astrophysics Data System (ADS)

    Nasdala, Lutz; Miletich, Ronald; Ruschel, Katja; Váczi, Tamás

    2008-12-01

    Pressure-induced changes of Raman band parameters of four natural, gem-quality zircon samples with different degrees of self-irradiation damage, and synthetic ZrSiO4 without radiation damage, have been studied under hydrostatic compression in a diamond anvil cell up to ~10 GPa. Radiation-damaged zircon shows similar up-shifts of internal SiO4 stretching modes at elevated pressures as non-damaged ZrSiO4. Only minor changes of band-widths were observed in all cases. This makes it possible to estimate the degree of radiation damage from the width of the ν3(SiO4) band of zircon inclusions in situ, almost independent from potential “fossilized pressures” or compressive strain acting on the inclusions. An application is the non-destructive analysis of gemstones such as corundum or spinel: broadened Raman bands are a reliable indicator of self-irradiation damage in zircon inclusions, whose presence allows one to exclude artificial color enhancement by high-temperature treatment of the specimen.

  16. Estimate of Cosmic Muon Background for Shallow Underground Neutrino Detectors

    NASA Astrophysics Data System (ADS)

    Casimiro, E.; Simão, F. R. A.; Anjos, J. C.

    One of the severe limitations in detecting neutrino signals from nuclear reactors is that the copious cosmic ray background imposes the use of a time veto upon the passage of the muons to reduce the number of fake signals due to muon-induced spallation neutrons. For this reason neutrino detectors are usually located underground, with a large overburden. However there are practical limitations that do restrain from locating the detectors at large depths underground. In order to decide the depth underground at which the Neutrino Angra Detector (currently in preparation) should be installed, an estimate of the cosmogenic background in the detector as a function of the depth is required. We report here a simple analytical estimation of the muon rates in the detector volume for different plausible depths, assuming a simple plain overburden geometry. We extend the calculation to the case of the San Onofre neutrino detector and to the case of the Double Chooz neutrino detector, where other estimates or measurements have been performed. Our estimated rates are consistent.

  17. Cadmium, type 2 diabetes, and kidney damage in a cohort of middle-aged women

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Barregard, Lars, E-mail: lars.barregard@amm.gu.se; Bergström, Göran, E-mail: goran.bergstrom@wlab.gu.se; Department of Molecular and Clinical Medicine, University of Gothenburg, SE-405 30 Gothenburg

    Background: It has been proposed that diabetic patients are more sensitive to the nephrotoxicity of cadmium (Cd) compared to non-diabetics, but few studies have examined this in humans, and results are inconsistent. Aim: To test the hypothesis that women with type 2 diabetes mellitus (DM) or impaired glucose tolerance (IGT) have higher risk of kidney damage from cadmium compared to women with normal glucose tolerance (NGT). Methods: All 64-year-old women in Gothenburg, Sweden, were invited to a screening examination including repeated oral glucose tolerance tests. Random samples of women with DM, IGT, and NGT were recruited for further clinical examinations.more » Serum creatinine was measured and used to calculate estimated glomerular filtration rate (eGFR). Albumin (Alb) and retinol-binding protein (RBP) were analyzed in a 12 h urine sample. Cadmium in blood (B-Cd) and urine (U-Cd) was determined using inductively coupled plasma mass spectrometry. Associations between markers of kidney function (eGFR, Alb, and RBP) and quartiles of B-Cd and U-Cd were evaluated in models, including also blood pressure and smoking habits. Results: The mean B-Cd (n=590) was 0.53 µg/L (median 0.34 µg/L). In multivariable models, a significant interaction was seen between high B-Cd (upper quartile, >0.56 µg/L) and DM (point estimate +0.40 mg Alb/12 h, P=0.04). In stratified analyzes, the effect of high B-Cd on Alb excretion was significant in women with DM (53% higher Alb/12 h, P=0.03), but not in women with IGT or NGT. Models with urinary albumin adjusted for creatinine showed similar results. In women with DM, the multivariable odds ratio (OR) for microalbuminuria (>15 mg/12 h) was increased in the highest quartile of B-Cd vs. B-Cd quartiles 1–3 in women with DM (OR 4.2, 95% confidence interval 1.1–12). No such effect was found in women with IGT or NGT. There were no associations between B-Cd and eGFR or excretion of RBP, and no differences between women with DM, IGT, or NGT regarding effect of B-Cd on eGFR or RBP. Conclusion: The present study provides support for the hypothesis that women with DM have higher risk of renal glomerular damage from cadmium exposure compared to women without DM. - Highlights: • Cadmium in blood, kidney function, and glucose tolerance was examined in 590 women. • Blood cadmium was associated with albumin excretion in women with type 2 diabetes. • No such associations with cadmium were found in women without diabetes. • Women with type 2 diabetes have increased sensitivity to kidney damage from cadmium.« less

  18. Economic valuation of flood mitigation services: A case study from the Otter Creek, VT.

    NASA Astrophysics Data System (ADS)

    Galford, G. L.; Ricketts, T.; Bryan, K. L.; ONeil-Dunne, J.; Polasky, S.

    2014-12-01

    The ecosystem services provided by wetlands are widely recognized but difficult to quantify. In particular, estimating the effect of landcover and land use on downstream flood outcomes remains challenging, but is increasingly important in light of climate change predictions of increased precipitation in many areas. Economic valuation can help incorporate ecosystem services into decisions and enable communities to plan for climate and flood resiliency. Here we estimate the economic value of Otter Creek wetlands for Middlebury, VT in mitigating the flood that followed Tropical Storm Irene, as well as for ten historic floods. Observationally, hydrographs above and below the wetlands in the case of each storm indicated the wetlands functioned as a temporary reservoir, slowing the delivery of water to Middlebury. We compare observed floods, based on Middlebury's hydrograph, with simulated floods for scenarios without wetlands. To simulate these "without wetlands" scenarios, we assume the same volume of water was delivered to Middlebury, but in a shorter time pulse similar to a hydrograph upstream of the wetlands. For scenarios with and without wetlands, we map the spatial extent of flooding using LiDAR digital elevation data. We then estimate flood depth at each affected building, and calculate monetary losses as a function of the flood depth and house value using established depth damage relationships. For example, we expect damages equal to 20% of the houses value for a flood depth of two feet in a two-story home with a basement. We define the value of flood mitigation services as the difference in damages between the with and without wetlands scenario, and find that the Otter Creek wetlands reduced flood damage in Middlebury by 88% following Hurricane Irene. Using the 10 additional historic floods, we estimate an ongoing mean value of $400,000 in avoided damages per year. Economic impacts of this magnitude stress the importance of wetland conservation and warrant the consideration of ecosystem services in land use decisions. Our study indicates that here and elsewhere, green infrastructure may have to potential to increase the resilience of communities to projected changes in climate.

  19. Probabilistic models to estimate fire-induced cable damage at nuclear power plants

    NASA Astrophysics Data System (ADS)

    Valbuena, Genebelin R.

    Even though numerous PRAs have shown that fire can be a major contributor to nuclear power plant risk, there are some specific areas of knowledge related to this issue, such as the prediction of fire-induced damage to electrical cables and circuits, and their potential effects in the safety of the nuclear power plant, that still constitute a practical enigma, particularly for the lack of approaches/models to perform consistent and objective assessments. This report contains a discussion of three different models to estimate fire-induced cable damage likelihood given a specified fire profile: the kinetic, the heat transfer and the IR "K Factor" model. These models not only are based on statistical analysis of data available in the open literature, but to the greatest extent possible they use physics based principles to describe the underlying mechanism of failures that take place among the electrical cables upon heating due to external fires. The characterization of cable damage, and consequently the loss of functionality of electrical cables in fire is a complex phenomenon that depends on a variety of intrinsic factors such as cable materials and dimensions, and extrinsic factors such as electrical and mechanical loads on the cables, heat flux severity, and exposure time. Some of these factors are difficult to estimate even in a well-characterized fire, not only for the variability related to the unknown material composition and physical arrangements, but also for the lack of objective frameworks and theoretical models to study the behavior of polymeric wire cable insulation under dynamic external thermal insults. The results of this research will (1) help to develop a consistent framework to predict fire-induced cable failure modes likelihood, and (2) develop some guidance to evaluate and/or reduce the risk associated with these failure modes in existing and new power plant facilities. Among the models evaluated, the physics-based heat transfer model takes into account the properties and characteristics of the cables and cable materials, and the characteristics of the thermal insult. This model can be used to estimate the probability of cable damage under different thermal conditions.

  20. Estimation of probability of failure for damage-tolerant aerospace structures

    NASA Astrophysics Data System (ADS)

    Halbert, Keith

    The majority of aircraft structures are designed to be damage-tolerant such that safe operation can continue in the presence of minor damage. It is necessary to schedule inspections so that minor damage can be found and repaired. It is generally not possible to perform structural inspections prior to every flight. The scheduling is traditionally accomplished through a deterministic set of methods referred to as Damage Tolerance Analysis (DTA). DTA has proven to produce safe aircraft but does not provide estimates of the probability of failure of future flights or the probability of repair of future inspections. Without these estimates maintenance costs cannot be accurately predicted. Also, estimation of failure probabilities is now a regulatory requirement for some aircraft. The set of methods concerned with the probabilistic formulation of this problem are collectively referred to as Probabilistic Damage Tolerance Analysis (PDTA). The goal of PDTA is to control the failure probability while holding maintenance costs to a reasonable level. This work focuses specifically on PDTA for fatigue cracking of metallic aircraft structures. The growth of a crack (or cracks) must be modeled using all available data and engineering knowledge. The length of a crack can be assessed only indirectly through evidence such as non-destructive inspection results, failures or lack of failures, and the observed severity of usage of the structure. The current set of industry PDTA tools are lacking in several ways: they may in some cases yield poor estimates of failure probabilities, they cannot realistically represent the variety of possible failure and maintenance scenarios, and they do not allow for model updates which incorporate observed evidence. A PDTA modeling methodology must be flexible enough to estimate accurately the failure and repair probabilities under a variety of maintenance scenarios, and be capable of incorporating observed evidence as it becomes available. This dissertation describes and develops new PDTA methodologies that directly address the deficiencies of the currently used tools. The new methods are implemented as a free, publicly licensed and open source R software package that can be downloaded from the Comprehensive R Archive Network. The tools consist of two main components. First, an explicit (and expensive) Monte Carlo approach is presented which simulates the life of an aircraft structural component flight-by-flight. This straightforward MC routine can be used to provide defensible estimates of the failure probabilities for future flights and repair probabilities for future inspections under a variety of failure and maintenance scenarios. This routine is intended to provide baseline estimates against which to compare the results of other, more efficient approaches. Second, an original approach is described which models the fatigue process and future scheduled inspections as a hidden Markov model. This model is solved using a particle-based approximation and the sequential importance sampling algorithm, which provides an efficient solution to the PDTA problem. Sequential importance sampling is an extension of importance sampling to a Markov process, allowing for efficient Bayesian updating of model parameters. This model updating capability, the benefit of which is demonstrated, is lacking in other PDTA approaches. The results of this approach are shown to agree with the results of the explicit Monte Carlo routine for a number of PDTA problems. Extensions to the typical PDTA problem, which cannot be solved using currently available tools, are presented and solved in this work. These extensions include incorporating observed evidence (such as non-destructive inspection results), more realistic treatment of possible future repairs, and the modeling of failure involving more than one crack (the so-called continuing damage problem). The described hidden Markov model / sequential importance sampling approach to PDTA has the potential to improve aerospace structural safety and reduce maintenance costs by providing a more accurate assessment of the risk of failure and the likelihood of repairs throughout the life of an aircraft.

  1. Simulation of Detecting Damage in Composite Stiffened Panel Using Lamb Waves

    NASA Technical Reports Server (NTRS)

    Wang, John T.; Ross, Richard W.; Huang, Guo L.; Yuan, Fuh G.

    2013-01-01

    Lamb wave damage detection in a composite stiffened panel is simulated by performing explicit transient dynamic finite element analyses and using signal imaging techniques. This virtual test process does not need to use real structures, actuators/sensors, or laboratory equipment. Quasi-isotropic laminates are used for the stiffened panels. Two types of damage are studied. One type is a damage in the skin bay and the other type is a debond between the stiffener flange and the skin. Innovative approaches for identifying the damage location and imaging the damage were developed. The damage location is identified by finding the intersection of the damage locus and the path of the time reversal wave packet re-emitted from the sensor nodes. The damage locus is a circle that envelops the potential damage locations. Its center is at the actuator location and its radius is computed by multiplying the group velocity by the time of flight to damage. To create a damage image for estimating the size of damage, a group of nodes in the neighborhood of the damage location is identified for applying an image condition. The image condition, computed at a finite element node, is the zero-lag cross-correlation (ZLCC) of the time-reversed incident wave signal and the time reversal wave signal from the sensor nodes. This damage imaging process is computationally efficient since only the ZLCC values of a small amount of nodes in the neighborhood of the identified damage location are computed instead of those of the full model.

  2. Correlation between He-Ne scatter and 2.7-microm pulsed laser damage at coating defects.

    PubMed

    Porteus, J O; Spiker, C J; Franck, J B

    1986-11-01

    A reported correlation between defect-initiated pulsed laser damage and local predamage scatter in multilayer infrared mirror coatings has been analyzed in detail. Examination of a much larger data base confirms the previous result on dielectric-enhanced reflectors with polished substrates over a wide range of energy densities above the damage onset. Scatter signals from individual undamaged defects were detected using a He-Ne scatter probe with a focal spot that nearly coincides with the 150-microm-diam (D1/e(2)) focal spot of the damage-probe beam. Subsequent damage frequency measurements (1-on-1) were made near normal or at 45 degrees incidence with 100-ns pulses at 2.7-microm wavelength. The correlation is characterized by an increase in damage frequency with increasing predamage scatter signal and by equivalence of the defect densities indicated by the two probes. Characteristics of the correlation are compared with a simple model based on focal spot intensity profiles. Conditions that limit correlation are discussed, including variable scatter from defects and background scatter from diamond-turned substrates. Results have implication for nondestructive defect detection and coating quality control.

  3. Predicting infestation levels of the nantucket pine tip moth (Lepidoptera: Tortricidae) using pheromone traps

    Treesearch

    Christopher Asaro; C. Wayne Berisford

    2001-01-01

    There is considerable interest in using pheromone trap catches of the Nantucket pine tip moth, Rhyacionia frustrana (Conistock), to estimate or predict population density and damage. At six sites in the Georgia Piedmont, adult tip moths were monitored through one or more years using pheromone traps while population density and damage for each tip...

  4. Choosing to encourage or discourage: Perceived effectiveness of prescriptive and proscriptive messages

    Treesearch

    P.L. Winter; B.J. Sagarin; K. Rhoads; D.W. Barrett; R.B. Cialdini

    2000-01-01

    The estimated cost of repairing damage caused to recreational sites annually is in the hundreds of millions of dollars. These depreciative activities also reduce the quality of visitors’ experiences in the damaged areas. Indirect methods, such as visitor education through brochures and signs, continue to be the least controversial management approaches to depreciative...

  5. Hurricane Hugo: South Carolina Forest Land Research and Management Related to the Storm

    Treesearch

    Jacqueline L. Haymond; William R. Harms; [Editors

    1996-01-01

    Hurricane Hugo was probably one of the most destructive hurricanes to assault the forests of the Eastern United States in recorded history. Four and one-half million acres were damaged in North Carolina and South Carolina, an estimated 21.4 billion board feet of timber were destroyed or damaged, and several federally listed endangered species (red-cockaded woodpecker,...

  6. Medical Malpractice Reform and Employer-Sponsored Health Insurance Premiums

    PubMed Central

    Morrisey, Michael A; Kilgore, Meredith L; Nelson, Leonard (Jack)

    2008-01-01

    Objective Tort reform may affect health insurance premiums both by reducing medical malpractice premiums and by reducing the extent of defensive medicine. The objective of this study is to estimate the effects of noneconomic damage caps on the premiums for employer-sponsored health insurance. Data Sources/Study Setting Employer premium data and plan/establishment characteristics were obtained from the 1999 through 2004 Kaiser/HRET Employer Health Insurance Surveys. Damage caps were obtained and dated based on state annotated codes, statutes, and judicial decisions. Study Design Fixed effects regression models were run to estimate the effects of the size of inflation-adjusted damage caps on the weighted average single premiums. Data Collection/Extraction Methods State tort reform laws were identified using Westlaw, LEXIS, and statutory compilations. Legislative repeal and amendment of statutes and court decisions resulting in the overturning or repealing state statutes were also identified using LEXIS. Principal Findings Using a variety of empirical specifications, there was no statistically significant evidence that noneconomic damage caps exerted any meaningful influence on the cost of employer-sponsored health insurance. Conclusions The findings suggest that tort reforms have not translated into insurance savings. PMID:18522666

  7. Rapid assessment of household needs in the Houston area after Tropical Storm Allison.

    PubMed

    Waring, Stephen C; Reynolds, Kaye M; D'Souza, Gypsyamber; Arafat, Raouf R

    2002-09-01

    Tropical Storm Allison, which hit landfall near Galveston, Texas, on June 5, 2001, caused the most severe flood-related damage ever recorded in the Houston metropolitan area. The main goal of the public health response to tropical storm Allison was to evaluate the immediate health needs of the community. To estimate damage and household needs, we conducted a rapid needs assessment in the areas most affected by flooding with use of a modified cluster sampling method facilitated by Geographical Information Systems methodology. A total of 420 households participated in the survey, 210 each from the 2 sampling areas. We found a 4-fold increase in illness among persons living in flooded homes compared with those living in nonflooded homes. These findings suggest a need for rapid resolution of flood-related damage and the possibility that residents should seek temporary housing during clean-up and repair. In addition, we obtained reliable estimates of damage and household needs to help guide relief efforts. The findings underscore the usefulness of a rapid-needs assessment as a tool to identify actual health threats and to facilitate delivery of resources to those with the greatest and most immediate need.

  8. Neural Plasticity in Multiple Sclerosis: The Functional and Molecular Background

    PubMed Central

    Glabinski, Andrzej

    2015-01-01

    Multiple sclerosis is an autoimmune neurodegenerative disorder resulting in motor dysfunction and cognitive decline. The inflammatory and neurodegenerative changes seen in the brains of MS patients lead to progressive disability and increasing brain atrophy. The most common type of MS is characterized by episodes of clinical exacerbations and remissions. This suggests the presence of compensating mechanisms for accumulating damage. Apart from the widely known repair mechanisms like remyelination, another important phenomenon is neuronal plasticity. Initially, neuroplasticity was connected with the developmental stages of life; however, there is now growing evidence confirming that structural and functional reorganization occurs throughout our lifetime. Several functional studies, utilizing such techniques as fMRI, TBS, or MRS, have provided valuable data about the presence of neuronal plasticity in MS patients. CNS ability to compensate for neuronal damage is most evident in RR-MS; however it has been shown that brain plasticity is also preserved in patients with substantial brain damage. Regardless of the numerous studies, the molecular background of neuronal plasticity in MS is still not well understood. Several factors, like IL-1β, BDNF, PDGF, or CB1Rs, have been implicated in functional recovery from the acute phase of MS and are thus considered as potential therapeutic targets. PMID:26229689

  9. Air Emission Reduction Benefits of Biogas Electricity Generation at Municipal Wastewater Treatment Plants.

    PubMed

    Gingerich, Daniel B; Mauter, Meagan S

    2018-02-06

    Conventional processes for municipal wastewater treatment facilities are energy and materially intensive. This work quantifies the air emission implications of energy consumption, chemical use, and direct pollutant release at municipal wastewater treatment facilities across the U.S. and assesses the potential to avoid these damages by generating electricity and heat from the combustion of biogas produced during anaerobic sludge digestion. We find that embedded and on-site air emissions from municipal wastewater treatment imposed human health, environmental, and climate (HEC) damages on the order of $1.63 billion USD in 2012, with 85% of these damages attributed to the estimated consumption of 19 500 GWh of electricity by treatment processes annually, or 0.53% of the US electricity demand. An additional 11.8 million tons of biogenic CO 2 are directly emitted by wastewater treatment and sludge digestion processes currently installed at plants. Retrofitting existing wastewater treatment facilities with anaerobic sludge digestion for biogas production and biogas-fueled heat and electricity generation has the potential to reduce HEC damages by up to 24.9% relative to baseline emissions. Retrofitting only large plants (>5 MGD), where biogas generation is more likely to be economically viable, would generate HEC benefits of $254 annually. These findings reinforce the importance of accounting for use-phase embedded air emissions and spatially resolved marginal damage estimates when designing sustainable infrastructure systems.

  10. Determination on Damage Mechanism of the Planet Gear of Heavy Vehicle Final Drive

    NASA Astrophysics Data System (ADS)

    Ramdan, RD; Setiawan, R.; Sasmita, F.; Suratman, R.; Taufiqulloh

    2018-02-01

    The works focus on the investigation of damage mechanism of fractured in the form of spalling of the planet gears from the final drive assembly of 160-ton heavy vehicles. The objective of this work is to clearly understand the mechanism of damage. The work is the first stage of the on-going research on the remaining life estimation of such gears. The understanding of the damage mechanism is critical in order to provide accurate estimate of the gear’s remaining life with observed initial damage. The analysis was performed based on the metallurgy laboratory works, including visual observation, macro-micro fractography by optical stereo and optical microscope and micro-vickers hardness test. From visual observation it was observed pitting that form lining defect at common position, which is at gear flank position. From spalling sample it was observed ratchet mark at the boundary between macro pitting and the edge of fractured parts. Further observation on the cross-section of the samples by optical microscope confirm that initial micro pitting occur without spalling of the case hardened surface. Spalling occur when pitting achieve certain critical size, and occur at multiple initiation site of crack propagation. From the present research it was concluded that pitting was resulted due to repeated contact fatigue. In addition, development of micro to macro pitting as well as spalling occur at certain direction towards the top of the gear teeth.

  11. Micromechanical Modeling of Anisotropic Damage-Induced Permeability Variation in Crystalline Rocks

    NASA Astrophysics Data System (ADS)

    Chen, Yifeng; Hu, Shaohua; Zhou, Chuangbing; Jing, Lanru

    2014-09-01

    This paper presents a study on the initiation and progress of anisotropic damage and its impact on the permeability variation of crystalline rocks of low porosity. This work was based on an existing micromechanical model considering the frictional sliding and dilatancy behaviors of microcracks and the recovery of degraded stiffness when the microcracks are closed. By virtue of an analytical ellipsoidal inclusion solution, lower bound estimates were formulated through a rigorous homogenization procedure for the damage-induced effective permeability of the microcracks-matrix system, and their predictive limitations were discussed with superconducting penny-shaped microcracks, in which the greatest lower bounds were obtained for each homogenization scheme. On this basis, an empirical upper bound estimation model was suggested to account for the influences of anisotropic damage growth, connectivity, frictional sliding, dilatancy, and normal stiffness recovery of closed microcracks, as well as tensile stress-induced microcrack opening on the permeability variation, with a small number of material parameters. The developed model was calibrated and validated by a series of existing laboratory triaxial compression tests with permeability measurements on crystalline rocks, and applied for characterizing the excavation-induced damage zone and permeability variation in the surrounding granitic rock of the TSX tunnel at the Atomic Energy of Canada Limited's (AECL) Underground Research Laboratory (URL) in Canada, with an acceptable agreement between the predicted and measured data.

  12. Flood Damages- savings potential for Austrian municipalities and evidence of adaptation

    NASA Astrophysics Data System (ADS)

    Unterberger, C.

    2016-12-01

    Recent studies show that the number of extreme precipitation events has increased globally and will continue to do so in the future. These observations are particularly true for central, northern and north-eastern Europe. These changes in the patterns of extreme events have direct repercussions for policy makers. Rojas et al. (2013) find that until 2080, annual damages could increase by a factor of 17 (from €5,5 bn/year today to € 98 bn/year in 2080) in the event that no adaptation measures are taken. Steininger et al. (2015) find that climate and weather induced extreme events account for an annual current welfare loss of about € 1 billion in Austria. As a result, policy makers will need to understand the interaction between hazard, exposure and vulnerability, with the goal of achieving flood risk reduction. Needed is a better understanding of where exposure, vulnerability and eventually flood risk are highest, i.e. where to reduce risk first and which factors drive existing flood risk. This article analyzes direct flood losses as reported by 1153 Austrian municipalities between 2005 and 2013. To achieve comparability between flood damages and municipalities' ordinary spending, a "vulnerability threshold" is introduced suggesting that flood damages should be lower than 5% of municipalities' average annual ordinary spending. It is found that the probability that flood damages exceed this vulnerability threshold is 12%. To provide a reliable estimate for that exceedance probability the joint distribution of damages and spending is modelled by means of a copula approach. Based on the joint distribution, a Monte Carlo simulation is conducted to derive uncertainty ranges for the exceedance probability. To analyze the drivers of flood damages and the effect they have on municipalities' spending, two linear regression models are estimated. Hereby obtained results suggest that damages increase significantly for those municipalities located along the shores of the river Danube and decrease significantly for municipalities that experienced floods in the past- indicating successful adaptation. As for the relationship between flood damages and municipalities' spending, the regression results indicate that flood damages have a significant positive impact.

  13. 43 CFR 11.83 - Damage determination phase-use value methodologies.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... subject to standards governing its application? (vi) Are methodological inputs and assumptions supported... used for unique or difficult design and estimating conditions. This methodology requires the construction of a simple design for which an estimate can be found and applied to the unique or difficult...

  14. 43 CFR 11.83 - Damage determination phase-use value methodologies.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... subject to standards governing its application? (vi) Are methodological inputs and assumptions supported... used for unique or difficult design and estimating conditions. This methodology requires the construction of a simple design for which an estimate can be found and applied to the unique or difficult...

  15. 43 CFR 11.83 - Damage determination phase-use value methodologies.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... subject to standards governing its application? (vi) Are methodological inputs and assumptions supported... used for unique or difficult design and estimating conditions. This methodology requires the construction of a simple design for which an estimate can be found and applied to the unique or difficult...

  16. 43 CFR 11.83 - Damage determination phase-use value methodologies.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... subject to standards governing its application? (vi) Are methodological inputs and assumptions supported... used for unique or difficult design and estimating conditions. This methodology requires the construction of a simple design for which an estimate can be found and applied to the unique or difficult...

  17. 43 CFR 11.83 - Damage determination phase-use value methodologies.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... subject to standards governing its application? (vi) Are methodological inputs and assumptions supported... used for unique or difficult design and estimating conditions. This methodology requires the construction of a simple design for which an estimate can be found and applied to the unique or difficult...

  18. Energy Measurement Studies for CO2 Measurement with a Coherent Doppler Lidar System

    NASA Technical Reports Server (NTRS)

    Beyon, Jeffrey Y.; Koch, Grady J.; Vanvalkenburg, Randal L.; Yu, Jirong; Singh, Upendra N.; Kavaya, Michael J.

    2010-01-01

    The accurate measurement of energy in the application of lidar system for CO2 measurement is critical. Different techniques of energy estimation in the online and offline pulses are investigated for post processing of lidar returns. The cornerstone of the techniques is the accurate estimation of the spectrum of lidar signal and background noise. Since the background noise is not the ideal white Gaussian noise, simple average level estimation of noise level is not well fit in the energy estimation of lidar signal and noise. A brief review of the methods is presented in this paper.

  19. Estimate of the cosmological bispectrum from the MAXIMA-1 cosmic microwave background map.

    PubMed

    Santos, M G; Balbi, A; Borrill, J; Ferreira, P G; Hanany, S; Jaffe, A H; Lee, A T; Magueijo, J; Rabii, B; Richards, P L; Smoot, G F; Stompor, R; Winant, C D; Wu, J H P

    2002-06-17

    We use the measurement of the cosmic microwave background taken during the MAXIMA-1 flight to estimate the bispectrum of cosmological perturbations. We propose an estimator for the bispectrum that is appropriate in the flat sky approximation, apply it to the MAXIMA-1 data, and evaluate errors using bootstrap methods. We compare the estimated value with what would be expected if the sky signal were Gaussian and find that it is indeed consistent, with a chi(2) per degree of freedom of approximately unity. This measurement places constraints on models of inflation.

  20. Flat Surface Damage Detection System (FSDDS)

    NASA Technical Reports Server (NTRS)

    Williams, Martha; Lewis, Mark; Gibson, Tracy; Lane, John; Medelius, Pedro; Snyder, Sarah; Ciarlariello, Dan; Parks, Steve; Carrejo, Danny; Rojdev, Kristina

    2013-01-01

    The Flat Surface Damage Detection system (FSDDS} is a sensory system that is capable of detecting impact damages to surfaces utilizing a novel sensor system. This system will provide the ability to monitor the integrity of an inflatable habitat during in situ system health monitoring. The system consists of three main custom designed subsystems: the multi-layer sensing panel, the embedded monitoring system, and the graphical user interface (GUI). The GUI LABVIEW software uses a custom developed damage detection algorithm to determine the damage location based on the sequence of broken sensing lines. It estimates the damage size, the maximum depth, and plots the damage location on a graph. Successfully demonstrated as a stand alone technology during 2011 D-RATS. Software modification also allowed for communication with HDU avionics crew display which was demonstrated remotely (KSC to JSC} during 2012 integration testing. Integrated FSDDS system and stand alone multi-panel systems were demonstrated remotely and at JSC, Mission Operations Test using Space Network Research Federation (SNRF} network in 2012. FY13, FSDDS multi-panel integration with JSC and SNRF network Technology can allow for integration with other complementary damage detection systems.

  1. [Dendrolimus spp. damage monitoring by using NOAA/AVHRR data].

    PubMed

    Zhang, Yushu; Ban, Xianxiu; Chen, Pengshi; Feng, Rui; Ji, Ruipeng; Xiao, Yan

    2005-05-01

    This paper approached the feasibility of quantitatively monitoring Dendrolimus spp. damage by using NOAA/ AVHRR data. The damaged rate of needle leaf was used to represent Dendrolimus spp. harming degree, and < 30%, 30%-60% and > 60% of damaged rate was defined as low, medium and severe harming degree, respectively. The correlation equation of damaged rate and normalized vegetation index (NDVI) was established, based on the ground spectrum observation. The NDVI was 0.8823 when no damage occurred. A relative NDVI value of damaged to undamaged area was used to express the remote sensing index of low, medium and severe harming degree. The index was 1 for undamaged forest, and 0.78-1, 0.57-0.78 and < 0.57 for low, medium and severe harming degrees, respectively. The mixed pixels were separated by linear addable vertical vegetation index in the monitoring, and the quantitative monitoring and analysis was accomplished for years when the three damage degrees happened. It was shown that AVHRR data could be more available in quantitatively monitoring and analyzing serious damage, while low degree damage was difficult to distinguish by AVHRR data, due to the differences of surface properties and atmospheric influences, as well as the lower space resolution of NOAA/AVHRR. The damaged area estimated by AVHRR was 12.1%-14.3% lower than that by TM.

  2. Damage detection in composite panels based on mode-converted Lamb waves sensed using 3D laser scanning vibrometer

    NASA Astrophysics Data System (ADS)

    Pieczonka, Łukasz; Ambroziński, Łukasz; Staszewski, Wiesław J.; Barnoncel, David; Pérès, Patrick

    2017-12-01

    This paper introduces damage identification approach based on guided ultrasonic waves and 3D laser Doppler vibrometry. The method is based on the fact that the symmetric and antisymmetric Lamb wave modes differ in amplitude of the in-plane and out-of-plane vibrations. Moreover, the modes differ also in group velocities and normally they are well separated in time. For a given time window both modes can occur simultaneously only close to the wave source or to a defect that leads to mode conversion. By making the comparison between the in-plane and out-of-plane wave vector components the detection of mode conversion is possible, allowing for superior and reliable damage detection. Experimental verification of the proposed damage identification procedure is performed on fuel tank elements of Reusable Launch Vehicles designed for space exploration. Lamb waves are excited using low-profile, surface-bonded piezoceramic transducers and 3D scanning laser Doppler vibrometer is used to characterize the Lamb wave propagation field. The paper presents theoretical background of the proposed damage identification technique as well as experimental arrangements and results.

  3. Thermal modeling of lesion growth with radiofrequency ablation devices

    PubMed Central

    Chang, Isaac A; Nguyen, Uyen D

    2004-01-01

    Background Temperature is a frequently used parameter to describe the predicted size of lesions computed by computational models. In many cases, however, temperature correlates poorly with lesion size. Although many studies have been conducted to characterize the relationship between time-temperature exposure of tissue heating to cell damage, to date these relationships have not been employed in a finite element model. Methods We present an axisymmetric two-dimensional finite element model that calculates cell damage in tissues and compare lesion sizes using common tissue damage and iso-temperature contour definitions. The model accounts for both temperature-dependent changes in the electrical conductivity of tissue as well as tissue damage-dependent changes in local tissue perfusion. The data is validated using excised porcine liver tissues. Results The data demonstrate the size of thermal lesions is grossly overestimated when calculated using traditional temperature isocontours of 42°C and 47°C. The computational model results predicted lesion dimensions that were within 5% of the experimental measurements. Conclusion When modeling radiofrequency ablation problems, temperature isotherms may not be representative of actual tissue damage patterns. PMID:15298708

  4. How are flood risk estimates affected by the choice of return-periods?

    NASA Astrophysics Data System (ADS)

    Ward, P. J.; de Moel, H.; Aerts, J. C. J. H.

    2011-12-01

    Flood management is more and more adopting a risk based approach, whereby flood risk is the product of the probability and consequences of flooding. One of the most common approaches in flood risk assessment is to estimate the damage that would occur for floods of several exceedance probabilities (or return periods), to plot these on an exceedance probability-loss curve (risk curve) and to estimate risk as the area under the curve. However, there is little insight into how the selection of the return-periods (which ones and how many) used to calculate risk actually affects the final risk calculation. To gain such insights, we developed and validated an inundation model capable of rapidly simulating inundation extent and depth, and dynamically coupled this to an existing damage model. The method was applied to a section of the River Meuse in the southeast of the Netherlands. Firstly, we estimated risk based on a risk curve using yearly return periods from 2 to 10 000 yr (€ 34 million p.a.). We found that the overall risk is greatly affected by the number of return periods used to construct the risk curve, with over-estimations of annual risk between 33% and 100% when only three return periods are used. In addition, binary assumptions on dike failure can have a large effect (a factor two difference) on risk estimates. Also, the minimum and maximum return period considered in the curve affects the risk estimate considerably. The results suggest that more research is needed to develop relatively simple inundation models that can be used to produce large numbers of inundation maps, complementary to more complex 2-D-3-D hydrodynamic models. It also suggests that research into flood risk could benefit by paying more attention to the damage caused by relatively high probability floods.

  5. Overexpression of Human S100B Exacerbates Brain Damage and Periinfarct Gliosis After Permanent Focal Ischemia

    PubMed Central

    Mori, Takashi; Tan, Jun; Arendash, Gary W.; Koyama, Naoki; Nojima, Yoshiko; Town, Terrence

    2009-01-01

    Background and Purpose We have previously demonstrated that augmented and prolonged activation of astrocytes detrimentally influences both the subacute and chronic phases of cerebral ischemia. Furthermore, we have suggested that the astrocyte-derived protein S100B may be important in these pathogenic events. However, the causal relationship between S100B and exacerbation of brain damage in vivo remains to be elucidated. Methods Using transgenic mice overexpressing human S100B (Tg huS100B mice), we examined whether S100B plays a cardinal role in aggravation of brain damage after permanent middle cerebral artery occlusion (pMCAO). Results Tg huS100B mice had significantly larger infarct volumes and worse neurological deficits at any time point examined after pMCAO as compared with CD-1 background strain-matched control mice. Infarct volumes in Tg huS100B mice were significantly increased from 1 to 3 and 5 days after pMCAO (delayed infarct expansion), whereas those in control mice were not significantly altered. S100, glial fibrillary acidic protein, and Iba1 burdens in the periinfarct area were significantly increased through to 7 days after pMCAO in Tg huS100B mice, whereas those in control mice reached a plateau at 3 days after pMCAO. Conclusions These results provide genetic evidence that overexpression of human S100B acts to exacerbate brain damage and periinfarct reactive gliosis (astrocytosis and microgliosis) during the subacute phase of pMCAO. PMID:18451356

  6. Radon and leukemia in the Danish study: another source of dose.

    PubMed

    Harley, Naomi H; Robbins, Edith S

    2009-10-01

    An epidemiologic study of childhood leukemia in Denmark (2,400 cases; 6,697 controls) from 1968 to 1994 suggested a weak, but statistically significant, association of residential radon exposure and acute childhood lymphoblastic leukemia (ALL). The Danish study estimated a relative risk (RR) = 1.56 (95% CI, 1.05-2.30) for a cumulative exposure of 1,000 Bq m-3 y. For an exposure duration of 10 y their RR corresponds to a radon concentration of 100 Bq m-3. There are two dose pathways of interest where alpha particles could damage potential stem cells for ALL. One is the alpha dose to bone marrow, and two is the dose to bronchial mucosa where an abundance of circulating lymphocytes is found. Compared with an exposure of about 1 mSv y-1 from natural external background, radon and decay products contribute an additional 10 to 60% to the bone marrow equivalent dose. The other pathway for exposure of T (or B) lymphocytes is within the tracheobronchial epithelium (BE). Inhaled radon decay products deposit on the relatively small area of airway surfaces and deliver a significant dose to the nearby basal or mucous cells implicated in human lung cancer. Lymphocytes are co-located with basal cells and are half as abundant. Using a 10-y exposure to 100 Bq m-3, our dose estimates suggest that the equivalent dose to these lymphocytes could approach 1 Sv. The relatively high dose estimate to lymphocytes circulating through the BE, potential precursor cells for ALL, provides a dose pathway for an association.

  7. Quantitative comparison between in vivo DNA adduct formation from exposure to selected DNA-reactive carcinogens, natural background levels of DNA adduct formation and tumour incidence in rodent bioassays.

    PubMed

    Paini, Alicia; Scholz, Gabriele; Marin-Kuan, Maricel; Schilter, Benoît; O'Brien, John; van Bladeren, Peter J; Rietjens, Ivonne M C M

    2011-09-01

    This study aimed at quantitatively comparing the occurrence/formation of DNA adducts with the carcinogenicity induced by a selection of DNA-reactive genotoxic carcinogens. Contrary to previous efforts, we used a very uniform set of data, limited to in vivo rat liver studies in order to investigate whether a correlation can be obtained, using a benchmark dose (BMD) approach. Dose-response data on both carcinogenicity and in vivo DNA adduct formation were available for six compounds, i.e. 2-acetylaminofluorene, aflatoxin B1, methyleugenol, safrole, 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline and tamoxifen. BMD(10) values for liver carcinogenicity were calculated using the US Environmental Protection Agency BMD software. DNA adduct levels at this dose were extrapolated assuming linearity of the DNA adduct dose response. In addition, the levels of DNA adducts at the BMD(10) were compared to available data on endogenous background DNA damage in the target organ. Although for an individual carcinogen the tumour response increases when adduct levels increase, our results demonstrate that when comparing different carcinogens, no quantitative correlation exists between the level of DNA adduct formation and carcinogenicity. These data confirm that the quantity of DNA adducts formed by a DNA-reactive compound is not a carcinogenicity predictor but that other factors such as type of adduct and mutagenic potential may be equally relevant. Moreover, comparison to background DNA damage supports the notion that the mere occurrence of DNA adducts above or below the level of endogenous DNA damage is neither correlated to development of cancer. These data strongly emphasise the need to apply the mode of action framework to understand the contribution of other biological effect markers playing a role in carcinogenicity.

  8. The evaluation of oxidative DNA damage in children with brain damage using 8-hydroxydeoxyguanosine levels.

    PubMed

    Fukuda, Miho; Yamauchi, Hiroshi; Yamamoto, Hitoshi; Aminaka, Masahito; Murakami, Hiroshi; Kamiyama, Noriko; Miyamoto, Yusaku; Koitabashi, Yasushi

    2008-02-01

    Urinary and cerebrospinal fluid (CSF) levels of 8-hydroxydeoxyguanosine (8-OHdG) were examined to estimate the relevance of oxidative stress in children with brain damage. Urinary 8-OHdG levels were measured in 51 children with various forms of central nervous system (CNS) disorders (status epilepticus [SE], hypoxic-ischemic encephalopathy [HIE], CNS infections and chronic epilepsy) and these levels were compared with those in 51 healthy children. CSF 8-OHdG levels were measured in 25 children with brain damage and in 19 control subjects. In addition, urinary and CSF levels of 8-OHdG were compared between the children with brain damage and healthy children. Finally, the relationship between urinary and CSF levels of 8-OHdG was determined in 12 children that provided both urinary and CSF samples. Our results showed that urinary 8-OHdG levels in children with HIE and CNS infections were higher than those of controls (Steel test; p < 0.05 and p < 0.05, respectively) and that CSF 8-OHdG levels were higher in children with SE, HIE, and CNS infections than in control subjects (Steel test; p < 0.01, 0.05 and 0.05, respectively). In addition, a positive correlation between the levels of urinary and CSF 8-OHdG was noted in the 12 children that provided both CSF and urinary samples (Spearman's rank correlation; rho = 0.82, p < 0.01). Further, we observed changes in the urinary 8-OHdG in a patient with HHV-6 encephalopathy, and found that the changes correlated well with the patient's clinical condition. These results suggest that oxidative stress is strongly related to acute brain damage in children, and that 8-OHdG is a useful marker of brain damage. Therefore, repeated measurements of urinary 8-OHdG may be helpful in estimating the extent of brain damage.

  9. Relationships between Traumatic Symptoms and Environmental Damage Conditions among Children 8 Months after the 2011 Japan Earthquake and Tsunami

    PubMed Central

    Usami, Masahide; Iwadare, Yoshitaka; Kodaira, Masaki; Watanabe, Kyota; Aoki, Momoko; Katsumi, Chiaki; Matsuda, Kumi; Makino, Kazunori; Iijima, Sonoko; Harada, Maiko; Tanaka, Hiromi; Sasaki, Yoshinori; Tanaka, Tetsuya; Ushijima, Hirokage; Saito, Kazuhiko

    2012-01-01

    Background To evaluate relationships between traumatic symptoms and environmental damage conditions among children who survived the 2011 Great East Japan Earthquake and Tsunami. Methods The subjects were 12,524 children in kindergartens, elementary schools, and junior high schools in Ishinomaki City, Miyagi Prefecture, Japan. The Post Traumatic Stress Symptoms for Children 15 items (PTSSC-15), a self-completion questionnaire on traumatic symptoms, was distributed to the children and a questionnaire regarding environmental damage conditions affecting the children was distributed to their teachers. Of 12,524 questionnaires distributed, an effective response was obtained from 11,692 (93.3%). Results The PTSSC-15 score was significantly higher in females than in males among 4th to 6th grade students in elementary schools and among junior high school students. In terms of traumatic symptoms and environmental damage conditions, with the exception of kindergartners, children who had their houses damaged or experienced separation from family members had a significantly higher PTSSC-15 score than children who did not experience environmental damage. Except for kindergartners and 4th- to 6th-grade elementary school students, children who experienced evacuation had a significantly higher PTSSC-15 score. Conclusions This study demonstrated relationships between traumatic symptoms and environmental damage conditions in children who had suffered from the disaster. Factors examined in studying the relationship between environmental damage conditions and traumatic symptoms were gender, age, house damage, evacuation experience, and bereavement experience. It was critical not only to examine the traumatic symptoms of the children but also to collect accurate information about environmental damage conditions. PMID:23209817

  10. DNA damage in outdoor workers occupationally exposed to environmental air pollutants

    PubMed Central

    Tovalin, H; Valverde, M; Morandi, M T; Blanco, S; Whitehead, L; Rojas, E

    2006-01-01

    Background Health concerns about the exposure to genotoxic and carcinogenic agents in the air are particularly significant for outdoor workers in less developed countries. Aims To investigate the association between personal exposure to a group of air pollutants and severity of DNA damage in outdoor workers from two Mexican cities. Methods DNA damage (Comet assay) and personal exposure to volatile organic compounds, PM2.5, and ozone were investigated in 55 outdoor and indoor workers from México City and Puebla. Results In México City, outdoor workers had greater DNA damage, reflected by a longer tail length, than indoor workers (median 46.8 v 30.1 μm), and a greater percentage of highly damaged cells (cells with tail length ⩾41 μm); in Puebla, outdoor and indoor workers had similar DNA damage. There were more alkali labile sites in outdoor than indoor workers. The DNA damage magnitude was positively correlated with PM2.5 and ozone exposure. Outdoor and indoor workers with ⩾60% of highly damaged cells (highly damaged workers) had significantly higher exposures to PM2.5, ozone, and some volatile organic compounds. The main factors associated with the highly damaged workers were ozone, PM2.5, and 1‐ethyl‐2‐methyl benzene exposure. Conclusions With this approach, the effects of some air pollutants could be correlated with biological endpoints from the Comet assay. It is suggested that the use of personal exposure assessment and biological endpoints evaluation could be an important tool to generate a more precise assessment of the associated potential health risks. PMID:16556741

  11. Preliminary assessment of the ATHENA/WFI non-X-ray background

    NASA Astrophysics Data System (ADS)

    Perinati, Emanuele; Barbera, Marco; Diebold, Sebastian; Guzman, Alejandro; Santangelo, Andrea; Tenzer, Chris

    2017-12-01

    We present a preliminary assessment of the non-X-ray background for the WFI on board ATHENA conducted at IAAT in the context of the collaborative background and radiation damage working group activities. Our main result is that in the baseline configuration originally assumed for the camera the requirement on the level of non-X-ray background could not be met. In light of the results of Geant4 simulations we propose and discuss a possible optimization of the camera design and pinpoint some open issues to be addressed in the next phase of investigation. One of these concerns the possible contribution to the non-X-ray background from soft protons and ions funneled to the focal plane through the optics. This is not quantified at this stage, here we just briefly report on our ongoing activities aimed at validating the mechanisms of proton scattering at grazing incidence.

  12. Approach for Assessing Direct Flood Damages

    NASA Astrophysics Data System (ADS)

    Gaňová, Lenka; Zeleňáková, Martina; Słyś, Daniel; Purcz, Pavol

    2014-11-01

    This article presents a methodological approach to flood direct tangible damage - damage to assets and direct intangible damage - environmental damage and loss of life assessment. The assessment of flood risk is an essential part of the risk management approach, which is the conceptual basis for the EU directive 2007/60/ES on the assessment and management of flood risk. The purpose of this directive is to establish a framework for the assessment and management of flood risk, aiming at the reduction of the adverse consequences for human health, the environment, cultural heritage and economic activity associated with flood in the community. Overall, an accurate estimation of negative effects on assets, environment and people is important in order to be able to determine the economy, environmental and social flood risk level in a system and the effects of risk mitigation measures.

  13. DR Reactor VSR channel damage

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kempf, F.J.; Rawlins, J.K.

    1961-10-30

    On July 11, 1961 the Ball 3X System at DR Reactor was inadventently tripped. All vertical safety rods dropped and all channels were filled with balls. This report has the twofold purpose of documenting borescope observations of ten vertical rod channels at DR Reactor and recording the estimated extent of graphite damage resulting from the above incident. Channel damage data are presented on appended drawings. With suitable notations, the tracings of these drawings may be revised to reflect any future graphite damage. All vertical rod channels at DR Reactor were visually examined with a closed circuit television system during ballmore » removal efforts. Typical photographs of trapped balls and ledges, as viewed on the television monitor, are shown. Photographs of typical graphite damage, obtained through the borescope are also included in this report. 3 refs., 8 figs., 1 tab.« less

  14. [Core principles of treatment of corneal damage in patients with thyroid eye disease].

    PubMed

    Grusha, Y O; Ismailova, D S; Sherstneva, L V

    To develop a therapeutic approach and to estimate the efficiency of complex treatment of corneal damage in patients with thyroid eye disease (TED). The study enrolled 44 patients (52 eyes) divided into 2 groups depending on the severity of corneal damage. Treatment of those with severe involvement included pathogenetic measures (pulse steroid therapy and/or radiation therapy) and surgery (orbital decompression, eyelid and corneal surgery). As the result of the treatment, orbital inflammation decreased and the state of the cornea improved in all patients. The treatment of corneal damage in patients with TED may differ depending on numerous factors, such as the severity of corneal damage and activity of orbital inflammation. Taking into account the potential danger of corneal involvement, one should make efforts to early detection and management of the risk factors.

  15. Costs of abandoned coal mine reclamation and associated recreation benefits in Ohio.

    PubMed

    Mishra, Shruti K; Hitzhusen, Frederick J; Sohngen, Brent L; Guldmann, Jean-Michel

    2012-06-15

    Two hundred years of coal mining in Ohio have degraded land and water resources, imposing social costs on its citizens. An interdisciplinary approach employing hydrology, geographic information systems, and a recreation visitation function model, is used to estimate the damages from upstream coal mining to lakes in Ohio. The estimated recreational damages to five of the coal-mining-impacted lakes, using dissolved sulfate as coal-mining-impact indicator, amount to $21 Million per year. Post-reclamation recreational benefits from reducing sulfate concentrations by 6.5% and 15% in the five impacted lakes were estimated to range from $1.89 to $4.92 Million per year, with a net present value ranging from $14.56 Million to $37.79 Million. A benefit costs analysis (BCA) of recreational benefits and coal mine reclamation costs provides some evidence for potential Pareto improvement by investing limited resources in reclamation projects. Copyright © 2012 Elsevier Ltd. All rights reserved.

  16. Detection and localization of damage using empirical mode decomposition and multilevel support vector machine

    NASA Astrophysics Data System (ADS)

    Dushyanth, N. D.; Suma, M. N.; Latte, Mrityanjaya V.

    2016-03-01

    Damage in the structure may raise a significant amount of maintenance cost and serious safety problems. Hence detection of the damage at its early stage is of prime importance. The main contribution pursued in this investigation is to propose a generic optimal methodology to improve the accuracy of positioning of the flaw in a structure. This novel approach involves a two-step process. The first step essentially aims at extracting the damage-sensitive features from the received signal, and these extracted features are often termed the damage index or damage indices, serving as an indicator to know whether the damage is present or not. In particular, a multilevel SVM (support vector machine) plays a vital role in the distinction of faulty and healthy structures. Formerly, when a structure is unveiled as a damaged structure, in the subsequent step, the position of the damage is identified using Hilbert-Huang transform. The proposed algorithm has been evaluated in both simulation and experimental tests on a 6061 aluminum plate with dimensions 300 mm × 300 mm × 5 mm which accordingly yield considerable improvement in the accuracy of estimating the position of the flaw.

  17. Estimating rangeland runoff, soil erosion, and salt mobility and transport processes

    USDA-ARS?s Scientific Manuscript database

    Over 55% of sediment and salts entering the Colorado River are derived from accelerated soil erosion from federal rangelands with damages estimated to be $385 million per year. About 55% of the loading is derived from rangelands. This suggests a significant potential to reduce dissolved-solids loa...

  18. Adapting the CROPGRO cotton model to simulate cotton biomass and yield under southern root-knot nematode parasitism

    USDA-ARS?s Scientific Manuscript database

    Cotton (Gossypium hirsutum L.) yield losses by southern root-knot nematode [Meloidogyne incognita (Kofoid & White) Chitwood] (RKN) are usually estimated after significant damage has been caused. However, estimation of potential yield reduction before planting is possible by using crop simulation mod...

  19. 43 CFR 11.38 - Assessment Plan-preliminary estimate of damages.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... restoration, rehabilitation, replacement, and/or acquisition of equivalent resources for the injured natural resources; and the compensable value, as defined in § 11.83(c) of this part, of the injured natural... natural resources. (i) The preliminary estimate of costs should take into account the effects, or...

  20. 43 CFR 11.38 - Assessment Plan-preliminary estimate of damages.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... restoration, rehabilitation, replacement, and/or acquisition of equivalent resources for the injured natural resources; and the compensable value, as defined in § 11.83(c) of this part, of the injured natural... natural resources. (i) The preliminary estimate of costs should take into account the effects, or...

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