Sample records for debit pulse guide

  1. Determinants of debit cards acceptance: An empirical investigation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ismail, Shafinar; Adnan, Azimah; Azizi, Amsyar

    These days, most of the Malaysians realize that the consumption of debit card will help them to reduce the household debt. Thus, it is important to analyse the acceptance of debit cards for further enhancement and expanding its market share in Malaysia. In addition, there is lacked of research being conducted on the determinants affecting the acceptance of debit cards among Malaysians. Thus, the study aimed to investigate the factors affecting the acceptance of debit cards. This study focuses on payment methods, consumer attitude, and safety of debit card in acceptance of debit cards. Questionnaires were distributed to the 300more » respondents. The sampling procedure adopted was stratified random sampling. The data obtained were analysed using SPSS 20.0 which involves scale reliability, descriptive and regression analysis. The result indicates that payment methods, consumer attitude and safety are the determinants of debit cards acceptance. Safety is the best predictor as most of the customers are confidents to use debit cards because of the security being developed around these debit card transactions. The analyses presented in this study can be used by policymakers and managers as a guide to promote banking products and services. The findings achieved in this study will be of interest for practitioners and academics concerned with developments of the Malaysian banking industry.« less

  2. Determinants of debit cards acceptance: An empirical investigation

    NASA Astrophysics Data System (ADS)

    Ismail, Shafinar; Bakri, Mohamed Hariri; Zulkepli, Jafri; Adnan, Azimah; Azizi, Amsyar

    2014-12-01

    These days, most of the Malaysians realize that the consumption of debit card will help them to reduce the household debt. Thus, it is important to analyse the acceptance of debit cards for further enhancement and expanding its market share in Malaysia. In addition, there is lacked of research being conducted on the determinants affecting the acceptance of debit cards among Malaysians. Thus, the study aimed to investigate the factors affecting the acceptance of debit cards. This study focuses on payment methods, consumer attitude, and safety of debit card in acceptance of debit cards. Questionnaires were distributed to the 300 respondents. The sampling procedure adopted was stratified random sampling. The data obtained were analysed using SPSS 20.0 which involves scale reliability, descriptive and regression analysis. The result indicates that payment methods, consumer attitude and safety are the determinants of debit cards acceptance. Safety is the best predictor as most of the customers are confidents to use debit cards because of the security being developed around these debit card transactions. The analyses presented in this study can be used by policymakers and managers as a guide to promote banking products and services. The findings achieved in this study will be of interest for practitioners and academics concerned with developments of the Malaysian banking industry.

  3. The Use of University Debit Cards for Purchasing Cigarettes: An Opportunity for Tobacco Use Prevention on University Campuses

    ERIC Educational Resources Information Center

    Lazev, Amy B.; Norton, Tina R.; Collins, Bradley; Ma, Grace; Miller, Suzanne

    2012-01-01

    Aims: Young adults have the highest smoking rate of any age group in the United States. However, little is known about how young adults, including college students, access and pay for cigarettes--important information for guiding policies and prevention and intervention efforts. This study examined students' use of university debit cards, which…

  4. 31 CFR 370.22 - What requirements apply to a financial institution that debits a deposit account?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... financial institution that debits a deposit account? 370.22 Section 370.22 Money and Finance: Treasury... Entries § 370.22 What requirements apply to a financial institution that debits a deposit account? A financial institution that debits a deposit account upon receiving a debit initiated by us agrees to the...

  5. 26 CFR 301.6311-2 - Payment by credit card and debit card.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 26 Internal Revenue 18 2012-04-01 2012-04-01 false Payment by credit card and debit card. 301.6311....6311-2 Payment by credit card and debit card. (a) Authority to receive—(1) Payments by credit card and debit card. Internal revenue taxes may be paid by credit card or debit card as authorized by this...

  6. 26 CFR 301.6311-2 - Payment by credit card and debit card.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 26 Internal Revenue 18 2011-04-01 2011-04-01 false Payment by credit card and debit card. 301.6311....6311-2 Payment by credit card and debit card. (a) Authority to receive—(1) Payments by credit card and debit card. Internal revenue taxes may be paid by credit card or debit card as authorized by this...

  7. 26 CFR 301.6311-2 - Payment by credit card and debit card.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 26 Internal Revenue 18 2013-04-01 2013-04-01 false Payment by credit card and debit card. 301.6311....6311-2 Payment by credit card and debit card. (a) Authority to receive—(1) Payments by credit card and debit card. Internal revenue taxes may be paid by credit card or debit card as authorized by this...

  8. 26 CFR 301.6311-2 - Payment by credit card and debit card.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 26 Internal Revenue 18 2014-04-01 2014-04-01 false Payment by credit card and debit card. 301.6311....6311-2 Payment by credit card and debit card. (a) Authority to receive—(1) Payments by credit card and debit card. Internal revenue taxes may be paid by credit card or debit card as authorized by this...

  9. Guidelines for School Property Accounting in Colorado, Part II--General Fixed Asset Accounts.

    ERIC Educational Resources Information Center

    Stiverson, Clare L.

    The second publication of a series of three issued by the Colorado Department of Education is designed as a guide for local school districts in the development of a property accounting system. It defines and classifies groups of accounts whereby financial information, taken from inventory records, may be transcribed into debit and credit entries…

  10. 76 FR 43477 - Debit Card Interchange Fees and Routing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-20

    ...The Board is adopting an interim final rule and requesting comment on provisions in Regulation II (Debit Card Interchange Fees and Routing) adopted in accordance with Section 920(a)(5) of the Electronic Fund Transfer Act, which governs adjustments to debit interchange transaction fees for fraud-prevention costs. The provisions allow an issuer to receive an adjustment of 1 cent to its interchange transaction fee if the issuer develops, implements, and updates policies and procedures reasonably designed to identify and prevent fraudulent electronic debit transactions; monitor the incidence of, reimbursements received for, and losses incurred from fraudulent electronic debit transactions; respond appropriately to suspicious electronic debit transactions so as to limit the fraud losses that may occur and prevent the occurrence of future fraudulent electronic debit transactions; and secure debit card and cardholder data. If an issuer meets these standards and wishes to receive the adjustment, it must certify its eligibility to receive the fraud-prevention adjustment to the payment card networks in which the issuer participates.

  11. 77 FR 37892 - Notice of Proposed Information Collection Requests; Federal Student Aid; Electronic Debit Payment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-25

    ... the bank account information needed by ED to debit the applicant's account. The authority for the PDA... DEPARTMENT OF EDUCATION Notice of Proposed Information Collection Requests; Federal Student Aid; Electronic Debit Payment Option for Student Loans SUMMARY: The Preauthorized Debit Account (PDA) Application...

  12. 77 FR 52703 - Notice of Submission for OMB Review; Federal Student Aid; Electronic Debit Payment Option for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-30

    ... the bank account information needed by ED to debit the applicant's account. The authority for the PDA... Payment Option for Student Loans SUMMARY: The Preauthorized Debit Account (PDA) Application is used to... debt payments debited from their bank accounts. DATES: Interested persons are invited to submit...

  13. 77 FR 52319 - Notice of Submission for OMB Review; Federal Student Aid; Electronic Debit Payment Option for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-29

    ... the bank account information needed by ED to debit the applicant's account. The authority for the PDA... Payment Option for Student Loans SUMMARY: The Preauthorized Debit Account (PDA) Application is used to... debt payments debited from their bank accounts. DATES: Interested persons are invited to submit...

  14. 77 FR 10958 - International Services Surveys: BE-150, Quarterly Survey of Cross-Border Credit, Debit, and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-24

    ...-Border Credit, Debit, and Charge Card Transactions, to change the survey title, and to collect data in... from Quarterly Survey of Cross-Border Credit, Debit, and Charge Card Transactions to Quarterly Survey... Survey of Cross-Border Credit, Debit, and Charge Card Transactions to Quarterly Survey of Payment Card...

  15. 31 CFR 363.38 - What happens if my financial institution returns an ACH debit?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... TreasuryDirect § 363.38 What happens if my financial institution returns an ACH debit? If your designated financial institution returns an ACH debit, we reserve the right to reinitiate the debit at our option. We.... We are not responsible for any fees your financial institution may charge relating to returned ACH...

  16. School lunch debit card payment systems are associated with lower nutrition and higher calories.

    PubMed

    Just, David R; Wansink, Brian

    2014-01-01

    Debit card payment systems are known to induce more frivolous purchases in adults, but their impact on children is unknown. Using a national survey of 2,314 public school students in the United States, food purchases in schools with debit-only systems to those in schools with both debit and cash options are compared. Students in debit and cash schools purchase more fresh fruit and vegetables and fewer total calories. Payment systems with cash options have a lower purchase incidence of less healthy foods and higher purchase incidence of more healthy foods. © 2013 The Obesity Society.

  17. 36 CFR 1254.84 - How may I use a debit card for copiers in the Washington, DC, area?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ..., money order, debit card, or credit card. Your researcher identification card number as encoded on the... 1253 of this chapter, you may use cash or credit card to purchase a debit card from the vending... 36 Parks, Forests, and Public Property 3 2010-07-01 2010-07-01 false How may I use a debit card...

  18. Infrastructure performance of irrigation canal to irrigation efficiency of irrigation area of Candi Limo in Mojokerto District

    NASA Astrophysics Data System (ADS)

    Kisnanto, S.; Hadiani, R. R. R.; Ikhsan, C.

    2018-03-01

    Performance is a measure of infrastructure success in delivering the benefits corresponding it’s design implementation. Debit efficiency is a comparison between outflow debit and inflow debit. Irrigation canal performance is part of the overall performance aspects of an irrigation area. The greater of the canal performance will be concluded that the canal is increasingly able to meet the planned benefits, need to be seen its comparison between the performance and debit efficiency of the canal. The existing problems in the field that the value of the performance of irrigation canals are not always comparable to the debit efficiency. This study was conducted to describe the relationship between the performance of the canal to the canal debit efficiency. The study was conducted at Candi Limo Irrigation Area in Mojokerto Disctrict under the authority of Pemerintahan Provinsi Jawa Timur. The primary canal and secondary canal are surveyed to obtain data. The physical condition of the primary and secondary canals into the material of this study also. Primary and secondary canal performance based on the physical condition in the field. Measurement inflow and outflow debit into the data for the calculation of the debit efficiency. The instrument used in this study such as the current meter for debit measurements in the field as a solution when there is a building measure in the field were damaged, also using the meter and the camera. Permen PU No.32 is used to determine the value of the performance of the canal, while the efficiency analysis to calculate a comparison value between outflow and inflow debit. The process of data running processing by performing the measurement and calculation of the performance of the canal, the canal debit efficiency value calculation, and display a graph of the relationship between the value of the performance with the debit efficiency in each canal. The expected results of this study that the performance value on the primary canal in the range of 0 to 100 % with debit efficiency value in the range of 0 to 100 %, while for the secondary canal 1 has a performance range between 0 to 100% with efficiency ranges between 0 to 100%, the performance of the secondary canals 2 ranges between 0 to 100% with efficiencies ranging from 0 to 100%, the secondary canal 3 performance ranges between 0 to 100% efficiency ranges between 0 to 100%, the secondary canal 4 performance ranges between 0 to 100% efficiency ranges between 0 to 100% and secondary canals 5 performance ranges between 0 to 100% efficiency ranges between 0 to 100%. For the tendency to expect from the performance and efficiency of the debit canal can have a proportional clockwise or counterclockwise, which amount can be random. The tendency to be graphed the relationship between performance and efficiency of the debit of each segment studied canal.

  19. 12 CFR Supplement I to Part 1005 - Official Interpretations

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... used to capture the Magnetic Ink Character Recognition (MICR) encoding to initiate a one-time automated clearinghouse (ACH) debit. For example, if a consumer authorizes a one-time ACH debit from the consumer's... involved at the time of the transaction, if the consumer's asset account is subsequently debited for the...

  20. 12 CFR Supplement I to Part 1005 - Official Interpretations

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... used to capture the Magnetic Ink Character Recognition (MICR) encoding to initiate a one-time automated clearinghouse (ACH) debit. For example, if a consumer authorizes a one-time ACH debit from the consumer's... involved at the time of the transaction, if the consumer's asset account is subsequently debited for the...

  1. 76 FR 66872 - International Services Surveys: Amendments to the BE-150, Quarterly Survey of Cross-Border Credit...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-28

    ...-Border Credit, Debit, and Charge Card Transactions AGENCY: Bureau of Economic Analysis, Commerce. ACTION... information on the BE-150, Quarterly Survey of Cross-Border Credit, Debit, and Charge Card Transactions... change the survey title from Quarterly Survey of Cross-Border Credit, Debit, and Charge Card Transactions...

  2. 12 CFR Appendix B to Part 360 - Debit/Credit File Structure

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 4 2010-01-01 2010-01-01 false Debit/Credit File Structure B Appendix B to Part 360 Banks and Banking FEDERAL DEPOSIT INSURANCE CORPORATION REGULATIONS AND STATEMENTS OF GENERAL POLICY RESOLUTION AND RECEIVERSHIP RULES Pt. 360, App. B Appendix B to Part 360—Debit/Credit File...

  3. 76 FR 67755 - Privacy Act of 1974; Department of Homeland Security U.S. Customs and Border Protection DHS/CBP...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-02

    ... 1974; Department of Homeland Security U.S. Customs and Border Protection DHS/CBP-003 Credit/Debit Card... Security/U.S Customs and Border Protection--003 Credit/Debit Card Data System of Records.'' This system... any credit and debit card transactions with it has with individuals. Additionally, the Department of...

  4. 12 CFR 222.91 - Duties of card issuers regarding changes of address.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... described in § 222.90(a) that issues a debit or credit card (card issuer). (b) Definitions. For purposes of this section: (1) Cardholder means a consumer who has been issued a credit or debit card. (2) Clear and... notification of a change of address for a consumer's debit or credit card account and, within a short period of...

  5. 31 CFR 370.24 - What right does the Bureau of the Public Debt have to terminate or suspend debit entries?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false What right does the Bureau of the... Entries § 370.24 What right does the Bureau of the Public Debt have to terminate or suspend debit entries? We may terminate or suspend the availability of one or more debit entries in any case or class of...

  6. Correlation analysis of Standardized Precipitation Index (SPI) for the water debit and level of the Cisadane River during El Niño and La Niña years

    NASA Astrophysics Data System (ADS)

    Khoir, A. N.; Rohmah, M.; Nuryadi

    2018-03-01

    Hydrometeorological factor causes most disaster in Indonesia, and two of them are drought and flood. This study aims to correlate Standardized Precipitation Index (SPI) 3-monthly to water debit and water level in the Cisadane River. The monthly rainfall data from Serpong and Pasar Baru rain station from 2009 to 2011 when moderate El Niño and moderate La Niña happened. The correlation analysis between debit and water level to SPI 3-monthly used rain post of Serpong to represent the condition of the upstream area and rain post of Pasar Baru to represent the condition of the downstream area. The results showed that during La Niña year, the rainfall on the upstream area of the Cisadane River influenced the increase and the decrease in water debit and water level. Meanwhile, the rainfall on the downstream area of the river has an opposite effect on the increase and the decrease of debit and water level of the Pasar Baru. On the upstream area, the correlation between rainfall and water debit is 0.8, and the correlation between rainfall and water level is also 0.8. During El Niño year, the correlation was less than 0.5.

  7. 17 CFR 260.7a-18 - Legibility.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ..., mimeographing, typing or other markings shall be in black ink, except that debits in credit categories and credits in debit categories may be set forth in red or black ink, but shall in all cases be designated in...

  8. 17 CFR 260.7a-18 - Legibility.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ..., mimeographing, typing or other markings shall be in black ink, except that debits in credit categories and credits in debit categories may be set forth in red or black ink, but shall in all cases be designated in...

  9. 17 CFR 260.7a-18 - Legibility.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ..., mimeographing, typing or other markings shall be in black ink, except that debits in credit categories and credits in debit categories may be set forth in red or black ink, but shall in all cases be designated in...

  10. 17 CFR 260.7a-18 - Legibility.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ..., mimeographing, typing or other markings shall be in black ink, except that debits in credit categories and credits in debit categories may be set forth in red or black ink, but shall in all cases be designated in...

  11. 17 CFR 260.7a-18 - Legibility.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ..., mimeographing, typing or other markings shall be in black ink, except that debits in credit categories and credits in debit categories may be set forth in red or black ink, but shall in all cases be designated in...

  12. 78 FR 795 - Self-Regulatory Organizations; The Depository Trust Company; Notice of Filing of Proposed Rule...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-04

    ... the effect the transaction would have on such Participant's account, and determines whether any... the net debit balance to exceed the net debit cap is placed on a pending (recycling) queue until the...

  13. Unconditionally Secure Credit/Debit Card Chip Scheme and Physical Unclonable Function

    NASA Astrophysics Data System (ADS)

    Kish, Laszlo B.; Entesari, Kamran; Granqvist, Claes-Göran; Kwan, Chiman

    The statistical-physics-based Kirchhoff-law-Johnson-noise (KLJN) key exchange offers a new and simple unclonable system for credit/debit card chip authentication and payment. The key exchange, the authentication and the communication are unconditionally secure so that neither mathematics- nor statistics-based attacks are able to crack the scheme. The ohmic connection and the short wiring lengths between the chips in the card and the terminal constitute an ideal setting for the KLJN protocol, and even its simplest versions offer unprecedented security and privacy for credit/debit card chips and applications of physical unclonable functions (PUFs).

  14. 76 FR 27033 - Notice of Submission for OMB Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-10

    ... application collects the necessary bank account information that allows the U.S. Department to debit the... payments may provide bank account information that allows them to authorize electronic debiting of.... ACTION: Comment Request. SUMMARY: The Director, Information Collection Clearance Division, Privacy...

  15. 49 CFR 1242.39 - Lease rentals-debit and credit, other rents-debit and credit, and repairs billed to others...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... basis calculated for the separation of administration (account XX-26-01). (b) Separate all common credit expense accounts on the same percentages calculated for the separation of administration (account XX-26-01). ...

  16. 49 CFR 1242.31 - Lease rentals-debit and credit and other rents-debit and credit (accounts 31-17-00, 31-18-00, 31...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... separation of administration—other (account XX-19-06). (b) Separate all common credit expense accounts on the same percentages calculated for the separation of administration—other (account XX-19-06). ...

  17. 40 CFR 63.652 - Emissions averaging provisions.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... times the credits for the same period calculated according to paragraph (h) of this section. Compliance... used to calculate debits and credits from the time of the change forward, and the new values shall be... control design evaluation and documented engineering calculations. (2) For determining debits from...

  18. 40 CFR 63.652 - Emissions averaging provisions.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... times the credits for the same period calculated according to paragraph (h) of this section. Compliance... used to calculate debits and credits from the time of the change forward, and the new values shall be... control design evaluation and documented engineering calculations. (2) For determining debits from...

  19. Teaching Debits and Credits

    ERIC Educational Resources Information Center

    Mamos, Thomas

    1973-01-01

    One of the most difficult concepts for beginning accounting students is an understanding of debits and credits. A rule has been formulated which covers most other rules: Beginning balances and increases appear on the same side of the account as the account appears in the fundamental equation (assets = liabilities + capital). (SC)

  20. Teaching the Rules of Debit and Credit

    ERIC Educational Resources Information Center

    Potts, Andrew J.

    1974-01-01

    A fundamental method of explaining the basic accounting principles and concepts (debit, credit, basic accounting equation) which includes visual aids, reference to local businesses, and drill, does much toward increasing the student's skill and enhancing his understanding of the subject matter. (Sample transparencies are included.) (Author/AJ)

  1. 18 CFR 367.1860 - Account 186, Miscellaneous deferred debits.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY REGULATIONS UNDER THE PUBLIC UTILITY HOLDING COMPANY... COMPANIES SUBJECT TO THE PROVISIONS OF THE PUBLIC UTILITY HOLDING COMPANY ACT OF 2005, FEDERAL POWER ACT AND NATURAL GAS ACT Balance Sheet Chart of Accounts Deferred Debits § 367.1860 Account 186, Miscellaneous...

  2. 43 CFR 418.28 - Conditions of delivery.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... particulars including the known or estimated location and amounts; (3) The amount will not be included as a valid headgate delivery for purposes of computing the Project efficiency and resultant incentive credit... treated directly as a debit to Lahontan storage in the same manner as an efficiency debit. (b) District...

  3. 45 CFR 158.241 - Form of rebate.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... method that was used for payment, such as credit card or direct debit. ... in the form of a premium credit, lump-sum check, or, if an enrollee paid the premium using a credit card or direct debit, by lump-sum reimbursement to the account used to pay the premium. (2) Any rebate...

  4. 12 CFR 235.6 - Prohibition on circumvention, evasion, and net compensation.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... compensation. 235.6 Section 235.6 Banks and Banking FEDERAL RESERVE SYSTEM (CONTINUED) BOARD OF GOVERNORS OF... net compensation. An issuer may not receive net compensation from a payment card network with respect... network with respect to electronic debit transactions or debit card-related activities, other than...

  5. 12 CFR 235.6 - Prohibition on circumvention, evasion, and net compensation.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... compensation. 235.6 Section 235.6 Banks and Banking FEDERAL RESERVE SYSTEM (CONTINUED) BOARD OF GOVERNORS OF... net compensation. An issuer may not receive net compensation from a payment card network with respect... network with respect to electronic debit transactions or debit card-related activities, other than...

  6. 12 CFR 235.6 - Prohibition on circumvention, evasion, and net compensation.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... compensation. 235.6 Section 235.6 Banks and Banking FEDERAL RESERVE SYSTEM (CONTINUED) BOARD OF GOVERNORS OF... net compensation. An issuer may not receive net compensation from a payment card network with respect... network with respect to electronic debit transactions or debit card-related activities, other than...

  7. 18 CFR 301.7 - Average System Cost methodology functionalization.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... SYSTEM COST METHODOLOGY FOR SALES FROM UTILITIES TO BONNEVILLE POWER ADMINISTRATION UNDER NORTHWEST POWER... functionalization under its Direct Analysis assigns costs, revenues, debits or credits based upon the actual and/or...) Functionalization methods. (1) Direct analysis, if allowed or required by Table 1, assigns costs, revenues, debits...

  8. 12 CFR Supplement I to Part 205 - Official Staff Interpretations

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... about when funds may be debited from a consumer's account and the non-return of consumer checks by the... certain events. ii. Debits to consumer accounts for group insurance available only through the financial.... Making an additional account accessible through an existing access device is equivalent to issuing an...

  9. 7 CFR 1767.18 - Assets and other debits.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 12 2014-01-01 2013-01-01 true Assets and other debits. 1767.18 Section 1767.18... an experimental status. B. Amounts in this account shall be transferred to Account 101, Electric... considered as experimental. C. The depreciation on property in this account shall be charged to Account 403.8...

  10. 12 CFR Supplement I to Part 205 - Official Staff Interpretations

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ...) encoding to initiate a one-time ACH debit. For example, if a consumer authorizes a one-time ACH debit from... electronic terminal is involved at the time of the transaction, if the consumer's asset account is... receive a notice that the transaction will be processed as an EFT for each transaction at POS or each time...

  11. 12 CFR Supplement I to Part 205 - Official Staff Interpretations

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ...) encoding to initiate a one-time ACH debit. For example, if a consumer authorizes a one-time ACH debit from... electronic terminal is involved at the time of the transaction, if the consumer's asset account is... receive a notice that the transaction will be processed as an EFT for each transaction at POS or each time...

  12. 12 CFR 334.91 - Duties of card issuers regarding changes of address.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... STATEMENTS OF GENERAL POLICY FAIR CREDIT REPORTING Identity Theft Red Flags § 334.91 Duties of card issuers regarding changes of address. (a) Scope. This section applies to an issuer of a debit or credit card (card... been issued a credit or debit card. (2) Clear and conspicuous means reasonably understandable and...

  13. 12 CFR 41.91 - Duties of card issuers regarding changes of address.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... FAIR CREDIT REPORTING Identity Theft Red Flags § 41.91 Duties of card issuers regarding changes of address. (a) Scope. This section applies to an issuer of a debit or credit card (card issuer) that is a... means a consumer who has been issued a credit or debit card. (2) Clear and conspicuous means reasonably...

  14. 12 CFR 717.91 - Duties of card issuers regarding changes of address.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... AFFECTING CREDIT UNIONS FAIR CREDIT REPORTING Identity Theft Red Flags § 717.91 Duties of card issuers regarding changes of address. (a) Scope. This section applies to an issuer of a debit or credit card (card... means a member who has been issued a credit or debit card. (2) Clear and conspicuous means reasonably...

  15. 12 CFR 571.91 - Duties of card issuers regarding changes of address.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... FAIR CREDIT REPORTING Identity Theft Red Flags § 571.91 Duties of card issuers regarding changes of address. (a) Scope. This section applies to an issuer of a debit or credit card (card issuer) that is a... consumer who has been issued a credit or debit card. (2) Clear and conspicuous means reasonably...

  16. 75 FR 78286 - Self-Regulatory Organizations; Notice of Filing and Immediate Effectiveness of Proposed Rule...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-15

    ...-disciplinary actions, the Exchange would similarly not take action to debit a member account until all appeal...-disciplinary actions will be debited, and the amount due will appear on the members invoice prior to the actual... imposed by a Hearing Panel in connection with Disciplinary Violations. With respect to disciplinary...

  17. 18 CFR 367.2260 - Account 226, Unamortized discount on long-term debt-Debit.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ..., FEDERAL POWER ACT AND NATURAL GAS ACT Balance Sheet Chart of Accounts Long-Term Debt § 367.2260 Account... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Account 226, Unamortized discount on long-term debt-Debit. 367.2260 Section 367.2260 Conservation of Power and Water...

  18. 45 CFR 158.241 - Form of rebate.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... reimbursement using the same method that was used for payment, such as credit card or direct debit. [75 FR 74921... in the form of a premium credit, lump-sum check, or, if an enrollee paid the premium using a credit card or direct debit, by lump-sum reimbursement to the account used to pay the premium. (2) For each of...

  19. 16 CFR 681.2 - Duties of card issuers regarding changes of address.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... applies to a person described in § 681.1(a) that issues a debit or credit card (card issuer). (b... of address if it receives notification of a change of address for a consumer's debit or credit card... 16 Commercial Practices 1 2010-01-01 2010-01-01 false Duties of card issuers regarding changes of...

  20. 36 CFR 1254.84 - How may I use a debit card for copiers in the Washington, DC, area?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... NATIONAL ARCHIVES AND RECORDS ADMINISTRATION PUBLIC AVAILABILITY AND USE USING RECORDS AND DONATED... machines located in the research rooms. Inserting the debit card into a card reader connected to the copier... add value to your card using the vending machine in the research room or at the Cashier's Office. We...

  1. Data mining technique for a secure electronic payment transaction using MJk-RSA in mobile computing

    NASA Astrophysics Data System (ADS)

    G. V., Ramesh Babu; Narayana, G.; Sulaiman, A.; Padmavathamma, M.

    2012-04-01

    Due to the evolution of the Electronic Learning (E-Learning), one can easily get desired information on computer or mobile system connected through Internet. Currently E-Learning materials are easily accessible on the desktop computer system, but in future, most of the information shall also be available on small digital devices like Mobile, PDA, etc. Most of the E-Learning materials are paid and customer has to pay entire amount through credit/debit card system. Therefore, it is very important to study about the security of the credit/debit card numbers. The present paper is an attempt in this direction and a security technique is presented to secure the credit/debit card numbers supplied over the Internet to access the E-Learning materials or any kind of purchase through Internet. A well known method i.e. Data Cube Technique is used to design the security model of the credit/debit card system. The major objective of this paper is to design a practical electronic payment protocol which is the safest and most secured mode of transaction. This technique may reduce fake transactions which are above 20% at the global level.

  2. 36 CFR 1254.84 - How may I use a debit card for copiers in the Washington, DC, area?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...'s Office is closed or at any other time during the hours research rooms are open as cited in part... machines located in the research rooms. Inserting the debit card into a card reader connected to the copier... add value to your card using the vending machine in the research room or at the Cashier's Office. We...

  3. 36 CFR 1254.84 - How may I use a debit card for copiers in the Washington, DC, area?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...'s Office is closed or at any other time during the hours research rooms are open as cited in part... machines located in the research rooms. Inserting the debit card into a card reader connected to the copier... add value to your card using the vending machine in the research room or at the Cashier's Office. We...

  4. 36 CFR § 1254.84 - How may I use a debit card for copiers in the Washington, DC, area?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...'s Office is closed or at any other time during the hours research rooms are open as cited in part... machines located in the research rooms. Inserting the debit card into a card reader connected to the copier... add value to your card using the vending machine in the research room or at the Cashier's Office. We...

  5. 26 CFR 301.6103(k)(9)-1 - Disclosure of returns and return information relating to payment of tax by credit card and debit...

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 26 Internal Revenue 18 2013-04-01 2013-04-01 false Disclosure of returns and return information relating to payment of tax by credit card and debit card. 301.6103(k)(9)-1 Section 301.6103(k)(9)-1... ADMINISTRATION PROCEDURE AND ADMINISTRATION Information and Returns Returns and Records § 301.6103(k)(9)-1...

  6. 26 CFR 301.6103(k)(9)-1 - Disclosure of returns and return information relating to payment of tax by credit card and debit...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 26 Internal Revenue 18 2011-04-01 2011-04-01 false Disclosure of returns and return information relating to payment of tax by credit card and debit card. 301.6103(k)(9)-1 Section 301.6103(k)(9)-1... ADMINISTRATION PROCEDURE AND ADMINISTRATION Information and Returns Returns and Records § 301.6103(k)(9)-1...

  7. 26 CFR 301.6103(k)(9)-1 - Disclosure of returns and return information relating to payment of tax by credit card and debit...

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 26 Internal Revenue 18 2014-04-01 2014-04-01 false Disclosure of returns and return information relating to payment of tax by credit card and debit card. 301.6103(k)(9)-1 Section 301.6103(k)(9)-1... ADMINISTRATION PROCEDURE AND ADMINISTRATION Information and Returns Returns and Records § 301.6103(k)(9)-1...

  8. 26 CFR 301.6103(k)(9)-1 - Disclosure of returns and return information relating to payment of tax by credit card and debit...

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 26 Internal Revenue 18 2012-04-01 2012-04-01 false Disclosure of returns and return information relating to payment of tax by credit card and debit card. 301.6103(k)(9)-1 Section 301.6103(k)(9)-1... ADMINISTRATION PROCEDURE AND ADMINISTRATION Information and Returns Returns and Records § 301.6103(k)(9)-1...

  9. 26 CFR 301.6103(k)(9)-1 - Disclosure of returns and return information relating to payment of tax by credit card and debit...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 18 2010-04-01 2010-04-01 false Disclosure of returns and return information relating to payment of tax by credit card and debit card. 301.6103(k)(9)-1 Section 301.6103(k)(9)-1... ADMINISTRATION PROCEDURE AND ADMINISTRATION Information and Returns Returns and Records § 301.6103(k)(9)-1...

  10. Effect of water irrigation volume on Capsicum frutescens growth and plankton abundance in aquaponics system

    NASA Astrophysics Data System (ADS)

    Andriani, Y.; Dhahiyat, Y.; Zahidah; Subhan, U.; Iskandar; Zidni, I.; Mawardiani, T.

    2018-03-01

    This study aimed to understand Capsicum frutescens growth and plankton abundance in aquaponics culture. A Completely Randomized Design (CRD) with six treatments in triplicates comprising of treatment A (positive control using organic liquid fertilizer), B (negative control without fertilizer), C (drip irrigation aquaponics with a water debit of 100 ml/day/plant), D (drip irrigation aquaponics with a water debit of 150 ml/day/plant), E (drip irrigation with a water debit of 200 ml/day/plant), and F (drip irrigation aquaponics with a water debit of 250 ml/day/plant) was applied. The water used in treatments C, D, E, and F contained comet fish feces as fertilizer. C. frutescens growth and plankton abundance were observed. Analysis was conducted using analysis of variance for plant productivity and descriptive analysis for plankton abundance and water quality. The results of this study showed that the highest plant growth was seen in plants receiving F treatment with 50 ml/day drip irrigation. However, no significant difference was found when compared to the positive control with organic artificial fertilizer. Eleven types of phytoplankton and six types of zooplankton were found, with Stanieria sp. as the most abundant phytoplankton and Brachionus sp. and Epistylis sp. as the most abundant zooplanktons.

  11. Guiding of laser pulses in plasma waveguides created by linearly-polarized femtosecond laser pulses

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lemos, N.; Cardoso, L.; Geada, J.

    We experimentally demonstrate that plasma waveguides produced with ultra-short laser pulses (sub-picosecond) in gas jets are capable of guiding high intensity laser pulses. This scheme has the unique ability of guiding a high-intensity laser pulse in a plasma waveguide created by the same laser system in the very simple and stable experimental setup. A hot plasma column was created by a femtosecond class laser that expands into an on-axis parabolic low density profile suitable to act as a waveguide for high intensity laser beams. We have successfully guided ~10 15 W cm -2 laser pulses in a 8 mm longmore » hydrogen plasma waveguide with a 35% guiding efficiency.« less

  12. Guiding of laser pulses in plasma waveguides created by linearly-polarized femtosecond laser pulses

    DOE PAGES

    Lemos, N.; Cardoso, L.; Geada, J.; ...

    2018-02-16

    We experimentally demonstrate that plasma waveguides produced with ultra-short laser pulses (sub-picosecond) in gas jets are capable of guiding high intensity laser pulses. This scheme has the unique ability of guiding a high-intensity laser pulse in a plasma waveguide created by the same laser system in the very simple and stable experimental setup. A hot plasma column was created by a femtosecond class laser that expands into an on-axis parabolic low density profile suitable to act as a waveguide for high intensity laser beams. We have successfully guided ~10 15 W cm -2 laser pulses in a 8 mm longmore » hydrogen plasma waveguide with a 35% guiding efficiency.« less

  13. Direct Student Loans: Additional Steps Would Increase Borrowers' Awareness of Electronic Debiting and Reduce Federal Administrative Costs. Report to the Honorable James M. Jeffords, U.S. Senate.

    ERIC Educational Resources Information Center

    Ashby, Cornelia M.

    In November 1999, the U.S. Department of Education began offering a 0.25% interest rate reduction to borrowers under the Direct Loan program who agree to have their monthly loan payments automatically withdrawn from a bank account through its electronic debit account (EDA) program. The Department of Education submitted a justification to the…

  14. Preventing the threat of credit-card fraud: Factors influencing cashiers' identification-checking behavior.

    PubMed

    Downing, Christopher; Howard, E Henry; Goodwin, Christina; Geller, E Scott

    2016-01-01

    Two studies examined factors influencing cashiers' identification (ID)-checking behavior in order to inform the development of interventions to prevent credit-card fraud. In both studies, research assistants made credit purchases in various stores and noted the cashiers' ID-checking behavior. In the first study, the store type, whether the cashier swiped the credit/debit card, the amount of the purchase, and whether the credit/debit card was signed significantly influenced ID-checking behavior. In the second study, an A-B-A design was used to evaluate the impact of a "Check my ID" prompt placed on the credit/debit card. The prompt increased cashiers' ID-checking behavior from 5.9% at Baseline to 10.3% during the Intervention. When the prompt was removed, the cashiers' ID-checking behavior decreased to 7.2%. Implications for further intervention research to prevent credit-card fraud are discussed.

  15. Limitations of on-site dairy farm regulatory debits as milk quality predictors.

    PubMed

    Borneman, Darand L; Stiegert, Kyle; Ingham, Steve

    2015-03-01

    In the United States, compliance with grade A raw fluid milk regulatory standards is assessed via laboratory milk quality testing and by on-site inspection of producers (farms). This study evaluated the correlation between on-site survey debits being marked and somatic cell count (SCC) or standard plate count (SPC) laboratory results for 1,301 Wisconsin grade A dairy farms in 2012. Debits recorded on the survey form were tested as predictors of laboratory results utilizing ordinary least squares regression to determine if results of the current method for on-site evaluation of grade A dairy farms accurately predict SCC and SPC test results. Such a correlation may indicate that current methods of on-site inspection serve the primary intended purpose of assuring availability of high-quality milk. A model for predicting SCC was estimated using ordinary least squares regression methods. Step-wise selected regressors of grouped debit items were able to predict SCC levels with some degree of accuracy (adjusted R2=0.1432). Specific debit items, seasonality, and farm size were the best predictors of SCC levels. The SPC data presented an analytical challenge because over 75% of the SPC observations were at or below a 25,000 cfu/mL threshold but were recorded by testing laboratories as at the threshold value. This classic censoring problem necessitated the use of a Tobit regression approach. Even with this approach, prediction of SPC values based on on-site survey criteria was much less successful (adjusted R2=0.034) and provided little support for the on-site survey system as a way to inform farmers about making improvements that would improve SPC. The lower level of correlation with SPC may indicate that factors affecting SPC are more varied and differ from those affecting SCC. Further, unobserved deficiencies in postmilking handling and storage sanitation could enhance bacterial growth and increase SPC, whereas postmilking sanitation will have no effect on SCC because somatic cells do not reproduce in stored milk. Results suggest that close examination, and perhaps redefinition, of survey debits, along with making the survey coincident with SCC and SPC sampling, could make the on-site survey a better tool for ensuring availability of high-quality milk. Copyright © 2015 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

  16. Effect of Blade Curvature Angle of Savonius Horizontal Axis Water Turbine to the Power Generation

    NASA Astrophysics Data System (ADS)

    Apha Sanditya, Taufan; Prasetyo, Ari; Kristiawan, Budi; Hadi, Syamsul

    2018-03-01

    The water energy is one of potential alternative in creating power generation specifically for the picohydro energy. Savonius is a kind of wind turbine which now proposed to be operated utilizing the energy from low fluid flow. Researches about the utilization of Savonius turbine have been developed in the horizontal water pipelines and wave. The testing experimental on the Savonius Horizontal Axis Water Turbine (HAWT) by observing the effect of the blade curvature angle (ψ) of 110°, 120°, 130°, and 140° at the debit of 176.4 lpm, 345 lpm, 489.6 lpm, and 714 lpm in order to know the power output was already conducted. The optimal result in every debit variation was obtained in the blade curvature angle of 120°. In the maximum debit of 714 lpm with blade curvature angle of 120° the power output is 39.15 Watt with the coefficient power (Cp) of 0.23 and tip speed ratio (TSR) of 1.075.

  17. Limiting of microjoule femtosecond pulses in air-guided modes of a hollow photonic-crystal fiber

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Konorov, S.O.; Serebryannikov, E.E.; Sidorov-Biryukov, D.A.

    Self-phase-modulation-induced spectral broadening of laser pulses in air-guided modes of hollow photonic-crystal fibers (PCFs) is shown to allow the creation of fiber-optic limiters for high-intensity ultrashort laser pulses. The performance of PCF limiters is analyzed in terms of elementary theory of self-phase modulation. Experiments performed with 100 fs microjoule pulses of 800 nm Ti:sapphire laser radiation demonstrate the potential of hollow PCFs as limiters for 10 MW ultrashort laser pulses and show the possibility to switch the limiting level of output radiation energy by guiding femtosecond pulses in different PCF modes.

  18. Laser-guided energetic discharges over large air gaps by electric-field enhanced plasma filaments

    NASA Astrophysics Data System (ADS)

    Théberge, Francis; Daigle, Jean-François; Kieffer, Jean-Claude; Vidal, François; Châteauneuf, Marc

    2017-01-01

    Recent works on plasma channels produced during the propagation of ultrashort and intense laser pulses in air demonstrated the guiding of electric discharges along the laser path. However, the short plasma lifetime limits the length of the laser-guided discharge. In this paper, the conductivity and lifetime of long plasma channels produced by ultrashort laser pulses is enhanced efficiently over many orders of magnitude by the electric field of a hybrid AC-DC high-voltage source. The AC electric pulse from a Tesla coil allowed to stimulate and maintain the highly conductive channel during few milliseconds in order to guide a subsequent 500 times more energetic discharge from a 30-kV DC source. This DC discharge was laser-guided over an air gap length of two metres, which is more than two orders of magnitude longer than the expected natural discharge length. Long plasma channel induced by laser pulses and stimulated by an external high-voltage source opens the way for wireless and efficient transportation of energetic current pulses over long air gaps and potentially for guiding lightning.

  19. Laser-guided energetic discharges over large air gaps by electric-field enhanced plasma filaments

    PubMed Central

    Théberge, Francis; Daigle, Jean-François; Kieffer, Jean-Claude; Vidal, François; Châteauneuf , Marc

    2017-01-01

    Recent works on plasma channels produced during the propagation of ultrashort and intense laser pulses in air demonstrated the guiding of electric discharges along the laser path. However, the short plasma lifetime limits the length of the laser-guided discharge. In this paper, the conductivity and lifetime of long plasma channels produced by ultrashort laser pulses is enhanced efficiently over many orders of magnitude by the electric field of a hybrid AC-DC high-voltage source. The AC electric pulse from a Tesla coil allowed to stimulate and maintain the highly conductive channel during few milliseconds in order to guide a subsequent 500 times more energetic discharge from a 30-kV DC source. This DC discharge was laser-guided over an air gap length of two metres, which is more than two orders of magnitude longer than the expected natural discharge length. Long plasma channel induced by laser pulses and stimulated by an external high-voltage source opens the way for wireless and efficient transportation of energetic current pulses over long air gaps and potentially for guiding lightning. PMID:28053312

  20. Ultrasound-guided greater occipital nerve blocks and pulsed radiofrequency ablation for diagnosis and treatment of occipital neuralgia.

    PubMed

    Vanderhoek, Matthew David; Hoang, Hieu T; Goff, Brandon

    2013-09-01

    Occipital neuralgia is a condition manifested by chronic occipital headaches and is thought to be caused by irritation or trauma to the greater occipital nerve (GON). Treatment for occipital neuralgia includes medications, nerve blocks, and pulsed radiofrequency ablation (PRFA). Landmark-guided GON blocks are the mainstay in both the diagnosis and treatment of occipital neuralgia. Ultrasound is being utilized more and more in the chronic pain clinic to guide needle advancement when performing procedures; however, there are no reports of ultrasound used to guide a diagnostic block or PRFA of the GON. We report two cases in which ultrasound was used to guide diagnostic greater occipital nerve blocks and greater occipital nerve pulsed radiofrequency ablation for treatment of occipital neuralgia. Two patients with occipital headaches are presented. In Case 1, ultrasound was used to guide diagnostic blocks of the greater occipital nerves. In Case 2, ultrasound was utilized to guide placement of radiofrequency probes for pulsed radiofrequency ablation of the greater occipital nerves. Both patients reported immediate, significant pain relief, with continued pain relief for several months. Further study is needed to examine any difference in outcomes or morbidity between the traditional landmark method versus ultrasound-guided blocks and pulsed radiofrequency ablation of the greater occipital nerves.

  1. Ultrasound-Guided Greater Occipital Nerve Blocks and Pulsed Radiofrequency Ablation for Diagnosis and Treatment of Occipital Neuralgia

    PubMed Central

    VanderHoek, Matthew David; Hoang, Hieu T; Goff, Brandon

    2013-01-01

    Occipital neuralgia is a condition manifested by chronic occipital headaches and is thought to be caused by irritation or trauma to the greater occipital nerve (GON). Treatment for occipital neuralgia includes medications, nerve blocks, and pulsed radiofrequency ablation (PRFA). Landmark-guided GON blocks are the mainstay in both the diagnosis and treatment of occipital neuralgia. Ultrasound is being utilized more and more in the chronic pain clinic to guide needle advancement when performing procedures; however, there are no reports of ultrasound used to guide a diagnostic block or PRFA of the GON. We report two cases in which ultrasound was used to guide diagnostic greater occipital nerve blocks and greater occipital nerve pulsed radiofrequency ablation for treatment of occipital neuralgia. Two patients with occipital headaches are presented. In Case 1, ultrasound was used to guide diagnostic blocks of the greater occipital nerves. In Case 2, ultrasound was utilized to guide placement of radiofrequency probes for pulsed radiofrequency ablation of the greater occipital nerves. Both patients reported immediate, significant pain relief, with continued pain relief for several months. Further study is needed to examine any difference in outcomes or morbidity between the traditional landmark method versus ultrasound-guided blocks and pulsed radiofrequency ablation of the greater occipital nerves. PMID:24282778

  2. Intense laser pulse propagation in capillary discharge plasma channels

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hubbard, R. F.; Moore, C. I.; Sprangle, P.

    Optical guiding of intense laser pulses is required for plasma-based accelerator concepts such as the laser wakefield accelerator. Reported experiments have successfully transported intense laser pulses in the hollow plasma column produced by a capillary discharge. The hollow plasma has an index of refraction which peaks on-axis, thus providing optical guiding which overcomes beam expansion due to diffraction. In more recent experiments at Hebrew University, 800 nm wavelength, 0.1 mJ, 100 fs pulses have been guided in {approx}300 micron radius capillaries over distances as long as 6.6 cm. Simulations of these experiments using a 2-D nonlinear laser propagation model producemore » the expected optical guiding, with the laser pulse radius r{sub L} exhibiting oscillations about the equilibrium value predicted by an analytical envelope equation model. The oscillations are damped at the front of the pulse and grow in amplitude in the back of the pulse. This growth and damping is attributed to finite pulse length effects. Simulations also show that further ionization of the discharge plasma by the laser pulse may hollow the laser pulse and introduce modulations in the spot size. This ionization-defocusing effect is expected to be significant at the high intensities required for accelerator application. Capillary discharge experiments at much higher intensities are in progress on the Naval Research Laboratory T{sup 3} laser, and preliminary results are reported.« less

  3. Analysis of non-Gaussian laser mode guidance and evolution in leaky plasma channels

    NASA Astrophysics Data System (ADS)

    Djordjevic, Blagoje; Benedetti, Carlo; Schroeder, Carl; Esarey, Eric; Leemans, Wim

    2016-10-01

    The evolution and propagation of a non-Gaussian laser pulse under varying circumstances, including a typical matched parabolic channel as well as leaky channels, are investigated. It has previously been shown for a Gaussian pulse that matched guiding can be achieved using parabolic plasma channels. In the low power regime, it can be shown directly that for multi-mode pulses there is significant transverse beating. Given the adverse behavior of non-Gaussian pulses in traditional guiding designs, we examine the use of leaky channels to filter out higher modes as a means of optimizing laser conditions. The interaction between different modes can have an adverse effect on the laser pulse as it propagates through the primary channel. To improve guiding of the pulse we propose using leaky channels. Realistic plasma channel profiles are considered. Higher order mode content is lost through the leaky channel, while the fundamental mode remains well-guided. This is demonstrated using both numerical simulations as well as the source-dependent Laguerre-Gaussian modal expansion. In conclusion, an idealized plasma lens based on leaky channels is found to filter out the higher order modes and leave a near-Gaussian profile before the pulse enters the primary channel.

  4. Intense laser pulse propagation in capillary discharge plasma channels

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hubbard, R.F.; Moore, C.I.; Sprangle, P.

    Optical guiding of intense laser pulses is required for plasma-based accelerator concepts such as the laser wakefield accelerator. Reported experiments have successfully transported intense laser pulses in the hollow plasma column produced by a capillary discharge. The hollow plasma has an index of refraction which peaks on-axis, thus providing optical guiding which overcomes beam expansion due to diffraction. In more recent experiments at Hebrew University, 800 nm wavelength, 0.1 mJ, 100 fs pulses have been guided in {approximately}300 micron radius capillaries over distances as long as 6.6 cm. Simulations of these experiments using a 2-D nonlinear laser propagation model producemore » the expected optical guiding, with the laser pulse radius r{sub L} exhibiting oscillations about the equilibrium value predicted by an analytical envelope equation model. The oscillations are damped at the front of the pulse and grow in amplitude in the back of the pulse. This growth and damping is attributed to finite pulse length effects. Simulations also show that further ionization of the discharge plasma by the laser pulse may hollow the laser pulse and introduce modulations in the spot size. This ionization-defocusing effect is expected to be significant at the high intensities required for accelerator application. Capillary discharge experiments at much higher intensities are in progress on the Naval Research Laboratory T{sup 3} laser, and preliminary results are reported. {copyright} {ital 1999 American Institute of Physics.}« less

  5. Guiding of Long-Distance Electric Discharges by Combined Femtosecond and Nanosecond Pulses Emitted by Hybrid KrF Laser System

    DTIC Science & Technology

    2014-01-30

    AFRL-AFOSR-UK-TR-2014-0040 Guiding of long-distance electric discharges by combined femtosecond and nanosecond pulses emitted by...To) 27 September 2010 – 31 December 2013 4. TITLE AND SUBTITLE Guiding of long-distance electric discharges by combined femtosecond and...plasma channels in the atmosphere and laser guiding of high-voltage electric discharges . 15. SUBJECT TERMS EOARD, triggering

  6. Ionization assisted self-guiding of femtosecond laser pulses

    NASA Astrophysics Data System (ADS)

    Morozov, A.; Goltsov, A.; Chen, Q.; Scully, M.; Suckewer, S.

    2018-05-01

    We propose a new mechanism for the self-guiding of ultra-intense sub-picosecond laser pulses in gaseous media. It can be realized via optical field ionization by a laser pulse as it propagates inside an expanding cylindrical shock wave launched into ambient gas by a decayed plasma filament. In experiments, the filament was created in a hydrogen jet by a low energy femtosecond laser pre-pulse line focused with axicon lens. We demonstrated ionization-assisted guiding in structures with diameter as small as 14 μm and up to 3.5 mm long. The intensity reached 5 × 1017 W/cm2 in a single mode propagating for more than 100 Rayleigh lengths.

  7. Laser pulse coded signal frequency measuring device based on DSP and CPLD

    NASA Astrophysics Data System (ADS)

    Zhang, Hai-bo; Cao, Li-hua; Geng, Ai-hui; Li, Yan; Guo, Ru-hai; Wang, Ting-feng

    2011-06-01

    Laser pulse code is an anti-jamming measures used in semi-active laser guided weapons. On account of the laser-guided signals adopting pulse coding mode and the weak signal processing, it need complex calculations in the frequency measurement process according to the laser pulse code signal time correlation to meet the request in optoelectronic countermeasures in semi-active laser guided weapons. To ensure accurately completing frequency measurement in a short time, it needed to carry out self-related process with the pulse arrival time series composed of pulse arrival time, calculate the signal repetition period, and then identify the letter type to achieve signal decoding from determining the time value, number and rank number in a signal cycle by Using CPLD and DSP for signal processing chip, designing a laser-guided signal frequency measurement in the pulse frequency measurement device, improving the signal processing capability through the appropriate software algorithms. In this article, we introduced the principle of frequency measurement of the device, described the hardware components of the device, the system works and software, analyzed the impact of some system factors on the accuracy of the measurement. The experimental results indicated that this system improve the accuracy of the measurement under the premise of volume, real-time, anti-interference, low power of the laser pulse frequency measuring device. The practicality of the design, reliability has been demonstrated from the experimental point of view.

  8. Guiding out-migrating juvenile sea lamprey (Petromyzon marinus) with pulsed direct current

    USGS Publications Warehouse

    Johnson, Nicholas S.; Miehls, Scott M.

    2014-01-01

    Non-physical stimuli can deter or guide fish without affecting water flow or navigation and therefore have been investigated to improve fish passage at anthropogenic barriers and to control movement of invasive fish. Upstream fish migration can be blocked or guided without physical structure by electrifying the water, but directional downstream fish guidance with electricity has received little attention. We tested two non-uniform pulsed direct current electric systems, each having different electrode orientations (vertical versus horizontal), to determine their ability to guide out-migrating juvenile sea lamprey (Petromyzon marinus) and rainbow trout (Oncorhynchus mykiss). Both systems guided significantly more juvenile sea lamprey to a specific location in our experimental raceway when activated than when deactivated, but guidance efficiency decreased at the highest water velocities tested. At the electric field setting that effectively guided sea lamprey, rainbow trout were guided by the vertical electrode system, but most were blocked by the horizontal electrode system. Additional research should characterize the response of other species to non-uniform fields of pulsed DC and develop electrode configurations that guide fish over a range of water velocity.

  9. EMPTAC (Electromagnetic Pulse Test Aircraft) user's guide

    NASA Astrophysics Data System (ADS)

    Cleaveland, Dale R.; Burkhard, Avery

    1988-04-01

    This guide was established to give test managers a way to familiarize themselves with the Air Force Weapons Laboratory's electromagnetic pulse (EMP) test aircraft program located at Kirtland Air Force Base (KAFB), New Mexico. Brief descriptions of the available EMP test facilities at KAFB are also included. This guide should give prospective customers (users) adequate information to scope the magnitude of their test effort and to accomplish general planning without extensive involvement in test execution details.

  10. Qualitative evidence of a primary intervention point for elite athlete doping.

    PubMed

    Mazanov, Jason; Huybers, Twan; Connor, James

    2011-03-01

    Anti-doping activities in sport have shifted from secondary prevention (intervening after athletes have used) to educational strategies focused on primary prevention through promoting abstinence. There is no empirical evidence to guide targeting of anti-doping education initiatives. In this paper, a heuristic to guide education initiatives was derived by re-analysing a series of interviews (n=20) with athletes, coaches, sports managers, physiotherapists and sports nutritionists. The findings indicate primary prevention of doping may be enhanced by timing it around periods of career instability where athlete vulnerability to doping may increase as a function of winning or losing sponsorship. Sponsorship is broadly defined as financial (e.g. salary stipend) and non-financial support (e.g. training facilities). This provides a basis for targeting education interventions to promote abstinence. Two options are offered to mitigate the need to time prevention activity around career instability by lessening the effect of sponsorship on athlete doping. The first is liberalising access to legitimate performance enhancing technologies (e.g. training techniques or nutritional supplements). The second is to delay access to financial sponsorship (beyond living expenses) until retirement, with monetary gains (e.g. prize money) deposited into an account where penalties are debited if the athlete is caught doping. Copyright © 2010 Sports Medicine Australia. Published by Elsevier Ltd. All rights reserved.

  11. [Flexible Guidance of Ultra-Short Laser Pulses in Ophthalmic Therapy Systems].

    PubMed

    Blum, J; Blum, M; Rill, M S; Haueisen, J

    2017-01-01

    In the last 20 years, the role of ultrashort pulsed lasers in ophthalmology has become increasingly important. However, it is still impossible to guide ultra-short laser pulses with standard glass fibres. The highly energetic femtosecond pulses would destroy the fibre material, and non-linear dispersion effects would significantly change beam parameters. In contrast, photonic crystal fibres mainly guide the laser pulses in air, so that absorption and dispersive pulse broadening have essentially no effect. This article compares classical beam guidance with mirrors, lenses and prisms with photonic crystal fibres and describes the underlying concepts and the current state of technology. A classical mirror arm possesses more variable optical properties, while the HCF (Hollow-Core Photonic Crystal Fibre) must be matched in terms of the laser energy and the laser spectrum. In contrast, the HCF has more advantages in respect of handling, system integration and costs. For applications based on photodisruptive laser-tissue interaction, the relatively low damage threshold of photonic crystal fibres compared to classic beam guiding systems is unacceptable. If, however, pulsed laser radiation has a sufficiently low peak intensity, e.g. as used for plasma-induced ablation, photonic crystal fibres can definitely be considered as an alternative solution to classic beam guidance. Georg Thieme Verlag KG Stuttgart · New York.

  12. 47 CFR 32.4520 - Additional paid-in capital.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... SYSTEM OF ACCOUNTS FOR TELECOMMUNICATIONS COMPANIES Instructions for Balance Sheet Accounts § 32.4520... includable in Account 4510, Capital Stock, unless such difference results in a debit balance for that class...

  13. Laser post-processing of Inconel 625 made by selective laser melting

    NASA Astrophysics Data System (ADS)

    Witkin, David; Helvajian, Henry; Steffeney, Lee; Hansen, William

    2016-04-01

    The effect of laser remelting of surfaces of as-built Selective Laser Melted (SLM) Inconel 625 was evaluated for its potential to improve the surface roughness of SLM parts. Many alloys made by SLM have properties similar to their wrought counterparts, but surface roughness of SLM-made parts is much higher than found in standard machine shop operations. This has implications for mechanical properties of SLM materials, such as a large debit in fatigue properties, and in applications of SLM, where surface roughness can alter fluid flow characteristics. Because complexity and netshape fabrication are fundamental advantages of Additive Manufacturing (AM), post-processing by mechanical means to reduce surface roughness detracts from the potential utility of AM. Use of a laser to improve surface roughness by targeted remelting or annealing offers the possibility of in-situ surface polishing of AM surfaces- the same laser used to melt the powder could be amplitude modulated to smooth the part during the build. The effects of remelting the surfaces of SLM Inconel 625 were demonstrated using a CW fiber laser (IPG: 1064 nm, 2-50 W) that is amplitude modulated with a pulse profile to induce remelting without spallation or ablation. The process achieved uniform depth of melting and improved surface roughness. The results show that with an appropriate pulse profile that meters the heat-load, surface features such as partially sintered powder particles and surface connected porosity can be mitigated via a secondary remelting/annealing event.

  14. Debit Interchange Fee Study Act of 2011

    THOMAS, 112th Congress

    Sen. Tester, Jon [D-MT

    2011-03-15

    Senate - 03/15/2011 Read twice and referred to the Committee on Banking, Housing, and Urban Affairs. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  15. Consumer Debit Card Protection Act of 2014

    THOMAS, 113th Congress

    Sen. Warner, Mark R. [D-VA

    2014-04-02

    Senate - 04/02/2014 Read twice and referred to the Committee on Banking, Housing, and Urban Affairs. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  16. 17 CFR 256.01-13 - Submission of questions.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... UTILITY HOLDING COMPANY ACT OF 1935 General Instructions § 256.01-13 Submission of questions. To promote... consideration and decision. Balance Sheet Accounts: Assets and Other Debit Accounts 1. service company property ...

  17. 29 CFR 4.123 - Administrative limitations, variances, tolerances, and exemptions.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... servicing of cards (including credit cards, debit cards, purchase cards, smart cards, and similar card... military personnel in buying and selling homes (which shall not include actual moving or storage of...

  18. Filtering higher-order laser modes using leaky plasma channels

    NASA Astrophysics Data System (ADS)

    Djordjević, B. Z.; Benedetti, C.; Schroeder, C. B.; Esarey, E.; Leemans, W. P.

    2018-01-01

    Plasma structures based on leaky channels are proposed to filter higher-order laser mode content. The evolution and propagation of non-Gaussian laser pulses in leaky channels are studied, and it is shown that, for appropriate laser-plasma parameters, the higher-order laser mode content of the pulse may be removed while the fundamental mode remains well-guided. The behavior of multi-mode laser pulses is described analytically and numerically using envelope equations, including the derivation of the leakage coefficients, and compared to particle-in-cell simulations. Laser pulse propagation, with reduced higher-order mode content, improves guiding in parabolic plasma channels, enabling extended interaction lengths for laser-plasma accelerator applications.

  19. 17 CFR 256.236 - Taxes accrued.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... credited with the amount of taxes accrued during the accounting period, corresponding debits being made to... be kept so as to show for each class of taxes the amount accrued, the basis for the accrual, the...

  20. 31 CFR 370.26 - What limitations exist on liability?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... TRANSFERS RELATING TO UNITED STATES SECURITIES Debit Entries § 370.26 What limitations exist on liability? If we sustain a loss because a financial institution fails to handle an entry in accordance with this...

  1. 76 FR 43393 - Debit Card Interchange Fees and Routing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-20

    ... have increased at a faster pace. \\20\\ Card-not-present transactions occur when the card is not...; \\32\\ faster availability of funds; faster check-out at the point-of-sale; increased sales value and...

  2. 47 CFR 32.4341 - Net deferred tax liability adjustments.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... in Accounts 4100 and 4340 for: (1) Tax effects of temporary differences accounted for under the flow... rates (Federal, state and local). As tax rates increase or decrease, the offsetting debit or credit will...

  3. 78 FR 43920 - Agency Information Collection Activities; Proposed Collection; Comments Requested: Application To...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-22

    ... pay the transfer tax by credit or debit card, combine information currently captured on another form... Clearance Officer, Policy and Planning Staff, Justice Management Division, Department of Justice, Two...

  4. Pulse pressure variation-guided fluid therapy after cardiac surgery: a pilot before-and-after trial.

    PubMed

    Suzuki, Satoshi; Woinarski, Nicholas C Z; Lipcsey, Miklos; Candal, Cristina Lluch; Schneider, Antoine G; Glassford, Neil J; Eastwood, Glenn M; Bellomo, Rinaldo

    2014-12-01

    The aim of this study is to study the feasibility, safety, and physiological effects of pulse pressure variation (PPV)-guided fluid therapy in patients after cardiac surgery. We conducted a pilot prospective before-and-after study during mandatory ventilation after cardiac surgery in a tertiary intensive care unit. We introduced a protocol to deliver a fluid bolus for a PPV≥13% for at least >10 minutes during the intervention period. We studied 45 control patients and 53 intervention patients. During the intervention period, clinicians administered a fluid bolus on 79% of the defined PPV trigger episodes. Median total fluid intake was similar between 2 groups during mandatory ventilation (1297 mL [interquartile range 549-1968] vs 1481 mL [807-2563]; P=.17) and the first 24 hours (3046 mL [interquartile range 2317-3982] vs 3017 mL [2192-4028]; P=.73). After adjusting for several baseline factors, PPV-guided fluid management significantly increased fluid intake during mandatory ventilation (P=.004) but not during the first 24 hours (P=.47). Pulse pressure variation-guided fluid therapy, however, did not significantly affect hemodynamic, renal, and metabolic variables. No serious adverse events were noted. Pulse pressure variation-guided fluid management was feasible and safe during mandatory ventilation after cardiac surgery. However, its advantages may be clinically small. Copyright © 2014 Elsevier Inc. All rights reserved.

  5. Filamentation in Air with Ultrashort Mid-Infrared Pulses

    DTIC Science & Technology

    2011-05-09

    remote sensing [11, 12], lightning guiding [13–15], supercontinuum generation ( SCG ) [16], pulse compression [17], and THz generation [18]. Although...shock) and push the pulse toward positive times [23, 24, 46, 54, 55] [see Fig. 3(a) at ζ = 0.6]. Subsequently, the pulse collapses at ζ = 0.9, and SCG

  6. 26 CFR 48.6412-1 - Floor stocks credit or refund.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 4071, relating to tires of the type used on highway vehicles; and section 4081, relating to gasoline... by crediting the dealer's account may not exceed the undisputed debit balance due at the time the...

  7. 12 CFR 712.5 - What activities and services are preapproved for CUSOs?

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... services: (1) Automated teller machine (ATM) services; (2) Credit card and debit card services; (3) Data... brokerage or agency: (1) Agency for sale of insurance; (2) Provision of vehicle warranty programs; (3...

  8. 12 CFR 712.5 - What activities and services are preapproved for CUSOs?

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... services: (1) Automated teller machine (ATM) services; (2) Credit card and debit card services; (3) Data... brokerage or agency: (1) Agency for sale of insurance; (2) Provision of vehicle warranty programs; (3...

  9. 12 CFR 712.5 - What activities and services are preapproved for CUSOs?

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... services: (1) Automated teller machine (ATM) services; (2) Credit card and debit card services; (3) Data... brokerage or agency: (1) Agency for sale of insurance; (2) Provision of vehicle warranty programs; (3...

  10. 12 CFR 712.5 - What activities and services are preapproved for CUSOs?

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... services: (1) Automated teller machine (ATM) services; (2) Credit card and debit card services; (3) Data... brokerage or agency: (1) Agency for sale of insurance; (2) Provision of vehicle warranty programs; (3...

  11. 78 FR 24805 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Minimum...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-26

    ... Collection; Comment Request; Bank Secrecy Act Suspicious Activity Report Database Proposed Data Fields.'' The...; c. Commercial paper; d. Credit card; e. Debit card; f. Forex transactions; g. Futures/Options on...

  12. Air-guided photonic-crystal-fiber pulse-compression delivery of multimegawatt femtosecond laser output for nonlinear-optical imaging and neurosurgery

    NASA Astrophysics Data System (ADS)

    Lanin, Aleksandr A.; Fedotov, Il'ya V.; Sidorov-Biryukov, Dmitrii A.; Doronina-Amitonova, Lyubov V.; Ivashkina, Olga I.; Zots, Marina A.; Sun, Chi-Kuang; Ömer Ilday, F.; Fedotov, Andrei B.; Anokhin, Konstantin V.; Zheltikov, Aleksei M.

    2012-03-01

    Large-core hollow photonic-crystal fibers (PCFs) are shown to enable a fiber-format air-guided delivery of ultrashort infrared laser pulses for neurosurgery and nonlinear-optical imaging. With an appropriate dispersion precompensation, an anomalously dispersive 15-μm-core hollow PCF compresses 510-fs, 1070-nm light pulses to a pulse width of about 110 fs, providing a peak power in excess of 5 MW. The compressed PCF output is employed to induce a local photodisruption of corpus callosum tissues in mouse brain and is used to generate the third harmonic in brain tissues, which is captured by the PCF and delivered to a detector through the PCF cladding.

  13. A Cashless Society? The Plastic Revolution. Resources in Technology.

    ERIC Educational Resources Information Center

    Ritz, John M.

    1993-01-01

    Relates the history of credit cards, their evolution to current forms, and innovations (debit cards, token cards, smart cards). Considers their sociocultural impact. Provides a design brief, including objectives, resources, evaluation criteria, outcomes, and a quiz. (SK)

  14. Data acquisition system

    DOEpatents

    Phillips, David T.

    1979-01-01

    A data acquisition system capable of resolving transient pulses in the subnanosecond range. A pulse in an information carrying medium such as light is transmitted through means which disperse the pulse, such as a fiber optic light guide which time-stretches optical pulses by chromatic dispersion. This time-stretched pulse is used as a sampling pulse and is modulated by the signal to be recorded. The modulated pulse may be further time-stretched prior to being recorded. The recorded modulated pulse is unfolded to derive the transient signal by utilizing the relationship of the time-stretching that occurred in the original pulse.

  15. 31 CFR 543.407 - Payments from blocked accounts to satisfy obligations prohibited.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... to Money and Finance (Continued) OFFICE OF FOREIGN ASSETS CONTROL, DEPARTMENT OF THE TREASURY CôTE D... obligations prohibited. Pursuant to § 543.201, no debits may be made to a blocked account to pay obligations...

  16. 31 CFR 543.407 - Payments from blocked accounts to satisfy obligations prohibited.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... to Money and Finance (Continued) OFFICE OF FOREIGN ASSETS CONTROL, DEPARTMENT OF THE TREASURY CôTE D... obligations prohibited. Pursuant to § 543.201, no debits may be made to a blocked account to pay obligations...

  17. 49 CFR 1242.81 - Joint facility-debit and credit (accounts 37-55-00 and 38-55-00).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... percentages calculated for the separation of administration (account XX-55-01). Separate common credit expenses on the basis of the percentages calculated for the separation of administration (account XX-55-01). ...

  18. Guiding of High Laser Intensities in Long Plasma Channels

    NASA Astrophysics Data System (ADS)

    Levin, M.; Eisenmann, S.; Palchan, T.; Zigler, A.; Sugiyama, K.; Nakajima, K.; Kaganovich, D.; Hubbard, R. F.; Ting, A.; Gordon, D. F.; Sprangle, P.; Fraenkel, M.; Maman, S.; Henis, Z.

    Plasma channels have been widely used to guide intense laser pulses over many Rayleigh lengths. Using optimized segmented capillary discharges, we demonstrated guided propagation of ultra short (100 fs) high intensity (1016 W/cm-2, limited by the laser system) pulses over distances up to 12.6 cm and intensities above 1018W/cm2 for 1.5cm boron nitride capillary. Both radial and longitudinal density profiles of plasma channels were studied under various discharge conditions. A new diagnostic technique is presented in which the transport of a guided laser pulse at different delay times from the initiation of the discharge is sampled on a single discharge shot. Using external, 10 nsec Nd YAG laser of several tenths of milijoules to ignite polyethylene capillaries we have demonstrated channels of various length in density range of 1017 - 1019 cm-3 and up to 25% deep. The longitudinal profiles were found to be remarkably uniform in both short and long capillaries. The Boron Nitride capillary has provided a guiding medium that can withstand more than 1000 shots. Using these capillaries we have guided laser intensities above 1018W/cm2. The laser ignition of capillary discharge provided reliable almost jitter free approach. The concerns related to influence of relatively high current density flow through capillary on the injected electrons were studied extensively by us both theoretically and experimentally using a simple injection method. The method is based on the interaction of a high intensity laser pulse with a thin wire placed near capillary entrance. The influence of magnetic fields was found to be insignificant. Using this method we have studied transport of electrons though capillary discharge.

  19. 12 CFR 204.2 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... purchase securities for the account of, any customer (including another depository institution), involving... debit to an account of the customer before the securities are delivered. A deposit arises thereafter, if... comparable maturity to that purchased by the customer; (v) Any liability of a depository institution's...

  20. 76 FR 12342 - Notice of Proposed Information Collection Requests

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-07

    ... savings account. The application collects the necessary bank account information that allows the U.S... automatic debiting of all monthly payments may provide bank account information that allows them to... DEPARTMENT OF EDUCATION Notice of Proposed Information Collection Requests AGENCY: Department of...

  1. 31 CFR 535.902 - Set-offs by U.S. owned or controlled firms abroad.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... licensed to set-off their claims against Iran or Iranian entities by debit to blocked accounts held by them for Iran or Iranian entities. (b) The general license in paragraph (a) of this section is revoked as...

  2. 31 CFR 535.902 - Set-offs by U.S. owned or controlled firms abroad.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... licensed to set-off their claims against Iran or Iranian entities by debit to blocked accounts held by them for Iran or Iranian entities. (b) The general license in paragraph (a) of this section is revoked as...

  3. 31 CFR 535.902 - Set-offs by U.S. owned or controlled firms abroad.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... licensed to set-off their claims against Iran or Iranian entities by debit to blocked accounts held by them for Iran or Iranian entities. (b) The general license in paragraph (a) of this section is revoked as...

  4. 31 CFR 535.902 - Set-offs by U.S. owned or controlled firms abroad.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... licensed to set-off their claims against Iran or Iranian entities by debit to blocked accounts held by them for Iran or Iranian entities. (b) The general license in paragraph (a) of this section is revoked as...

  5. 76 FR 26678 - Withholding on Payments by Government Entities to Persons Providing Property or Services

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-09

    ... application of section 3402(t) to payments by debit cards, credit cards, stored value cards, and other payment cards. Proposed regulations under sections 3402(t), 3406, 6011, 6051, 6071, and 6302 of the Code were...

  6. 17 CFR 256.216 - Unappropriated retained earnings.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... retained earnings. This account shall include the balance, either debit or credit, arising from earnings... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Unappropriated retained earnings. 256.216 Section 256.216 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION...

  7. Dwell fatigue in two Ti alloys: An integrated crystal plasticity and discrete dislocation study

    NASA Astrophysics Data System (ADS)

    Zheng, Zebang; Balint, Daniel S.; Dunne, Fionn P. E.

    2016-11-01

    It is a well known and important problem in the aircraft engine industry that alloy Ti-6242 shows a significant reduction in fatigue life, termed dwell debit, if a stress dwell is included in the fatigue cycle, whereas Ti-6246 does not; the mechanistic explanation for the differing dwell debit of these alloys has remained elusive for decades. In this work, crystal plasticity modelling has been utilised to extract the thermal activation energies for pinned dislocation escape for both Ti alloys based on independent experimental data. This then allows the markedly different cold creep responses of the two alloys to be captured accurately and demonstrates why the observed near-identical rate sensitivity under non-dwell loading is entirely consistent with the dwell behaviour. The activation energies determined are then utilised within a recently developed thermally-activated discrete dislocation plasticity model to predict the strain rate sensitivities of the two alloys associated with nano-indentation into basal and prism planes. It is shown that Ti-6242 experiences a strong crystallographic orientation-dependent rate sensitivity while Ti-6246 does not which is shown to agree with recently published independent measurements; the dependence of rate sensitivity on indentation slip plane is also well captured. The thermally-activated discrete dislocation plasticity model shows that the incorporation of a stress dwell in fatigue loading leads to remarkable stress redistribution from soft to hard grains in the classical cold dwell fatigue rogue grain combination in alloy Ti-6242, but that no such load shedding occurs in alloy Ti-6246. The key property controlling the behaviour is the time constant of the thermal activation process relative to that of the loading. This work provides the first mechanistic basis to explain why alloy Ti-6242 shows a dwell debit but Ti-6246 does not.

  8. Ultra short laser pulse modification of wave guides

    NASA Astrophysics Data System (ADS)

    Rosenfeld, Arkadi; Ashkenasi, David

    2003-11-01

    The high peak powers of ultra short (ps and sub-ps) pulsed lasers available at relatively low single pulse energies potentially allow for a precise localization of photon energy, either on the surface or inside (transparent) materials. Three dimensional micro structuring of bulk transparent media without any sign of mechanical cracking has shown the potential of ultra short laser processing. In this study, the micro structuring of bulk transparent media was used to modify fused silica and especially the cladding-core interface in normal fused silica wave guides. The idea behind this technique is to enforce a local mismatch for total reflection at the interface at minimal mechanic stress to overcome the barrier for enhanced optical out-coupling. The laser-induced modifications were studied in dependence of pulse width, focal alignment, single pulse energy and pulse overlap. Micro traces with a thickness between 3 and 8 μm were generated with a spacing of 10 μm in the subsurface region using sub-ps and ps laser pulses at a wavelength of 800 nm. The optical leakage enforced by a micro spiral pattern is significant and can be utilized for medical applications or potentially also for telecommunications and fiber laser technology.

  9. Ultrashort laser pulse processing of wave guides for medical applications

    NASA Astrophysics Data System (ADS)

    Ashkenasi, David; Rosenfeld, Arkadi; Spaniol, Stefan B.; Terenji, Albert

    2003-06-01

    The availability of ultra short (ps and sub-ps) pulsed lasers has stimulated a growing interest in exploiting the enhanced flexibility of femtosecond and/or picosecond laser technology for micro-machining. The high peak powers available at relatively low single pulse energies potentially allow for a precise localization of photon energy, either on the surface or inside (transparent) materials. Three dimensional micro structuring of bulk transparent media without any sign of mechanical cracking has been demonstrated. In this study, the potential of ultra short laser processing was used to modify the cladding-core interface in normal fused silica wave guides. The idea behind this technique is to enforce a local mismatch for total reflection at the interface at minimal mechanic stress. The laser-induced modifications were studied in dependence of pulse width, focal alignment, single pulse energy and pulse overlap. Micro traces with a thickness between 3 and 8 μm were generated with a spacing of 10 μm in the sub-surface region using sub-ps and ps laser pulses at a wavelength of 800 nm. The optical leakage enforced by a micro spiral pattern is significant and can be utilized for medical applications or potentially also for telecommunications and fiber laser technology.

  10. 77 FR 3069 - Modification of Interlibrary Loan Fee Schedule

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-23

    ... collections of the National Agricultural Library (NAL). The revised fee schedule is based on the method of... through the Online Computer Library Center (OCLC) network's Interlibrary Fee Management program, a debit..., National Agricultural Library, 10301 Baltimore Avenue, Beltsville, MD 20705-2351. FOR FURTHER INFORMATION...

  11. Looking at Debit and Credit Card Fraud

    ERIC Educational Resources Information Center

    Porkess, Roger; Mason, Stephen

    2012-01-01

    This article, written jointly by a mathematician and a barrister, looks at some of the statistical issues raised by court cases based on fraud involving chip and PIN cards. It provides examples and insights that statistics teachers should find helpful. (Contains 4 tables and 1 figure.)

  12. 7 CFR 505.6 - Payment of fees.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Regulations of the Department of Agriculture (Continued) AGRICULTURAL RESEARCH SERVICE, DEPARTMENT OF AGRICULTURE NATIONAL AGRICULTURAL LIBRARY FEES FOR LOANS AND COPYING § 505.6 Payment of fees. NAL charges for interlibrary loans through OCLC's IFM Program (an electronic debit/credit payment program for libraries using...

  13. 7 CFR 505.6 - Payment of fees.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Regulations of the Department of Agriculture (Continued) AGRICULTURAL RESEARCH SERVICE, DEPARTMENT OF AGRICULTURE NATIONAL AGRICULTURAL LIBRARY FEES FOR LOANS AND COPYING § 505.6 Payment of fees. NAL charges for interlibrary loans through OCLC's IFM Program (an electronic debit/credit payment program for libraries using...

  14. Guiding supersonic projectiles using optically generated air density channels

    NASA Astrophysics Data System (ADS)

    Johnson, Luke A.; Sprangle, Phillip

    2015-09-01

    We investigate the feasibility of using optically generated channels of reduced air density to provide trajectory correction (guiding) for a supersonic projectile. It is shown that the projectile experiences a force perpendicular to its direction of motion as one side of the projectile passes through a channel of reduced air density. A single channel of reduced air density can be generated by the energy deposited from filamentation of an intense laser pulse. We propose changing the laser pulse energy from shot-to-shot to build longer effective channels. Current femtosecond laser systems with multi-millijoule pulses could provide trajectory correction of several meters on 5 km trajectories for sub-kilogram projectiles traveling at Mach 3.

  15. Pulsed-light imaging for fluorescence guided surgery under normal room lighting.

    PubMed

    Sexton, Kristian; Davis, Scott C; McClatchy, David; Valdes, Pablo A; Kanick, Stephen C; Paulsen, Keith D; Roberts, David W; Pogue, Brian W

    2013-09-01

    Fluorescence guided surgery (FGS) is an emerging technology that has demonstrated improved surgical outcomes. However, dim lighting conditions required by current FGS systems are disruptive to standard surgical workflow. We present a novel FGS system capable of imaging fluorescence under normal room light by using pulsed excitation and gated acquisition. Images from tissue-simulating phantoms confirm visual detection down to 0.25 μM of protoporphyrin IX under 125 μW/cm2 of ambient light, more than an order of magnitude lower than that measured with the Zeiss Pentero in the dark. Resection of orthotopic brain tumors in mice also suggests that the pulsed-light system provides superior sensitivity in vivo.

  16. Pulsed-light imaging for fluorescence guided surgery under normal room lighting

    PubMed Central

    Sexton, Kristian; Davis, Scott C.; McClatchy, David; Valdes, Pablo A.; Kanick, Stephen C.; Paulsen, Keith D.; Roberts, David W.; Pogue, Brian W.

    2013-01-01

    Fluorescence guided surgery (FGS) is an emerging technology that has demonstrated improved surgical outcomes. However, dim lighting conditions required bycurrent FGS systems are disruptive to standard surgical workflow. We present a novel FGS system capable of imaging fluorescence under normal room lightby using pulsed excitation and gated acquisition. Images from tissue-simulating phantoms confirm visual detection down to 0.25 μM of protopor-phyrin IX under 125 μW/cm2 of ambient light, more than an order of magnitude lower than that measured with the Zeiss Pentero in the dark. Resection of orthotopic brain tumors in mice also suggests that the pulsed-light system provides superior sensitivity in vivo. PMID:23988926

  17. MR-Guided Pulsed High-Intensity Focused Ultrasound Enhancement of Gene Therapy Combined With Androgen Deprivation and Radiotherapy for Prostate Cancer Treatment

    DTIC Science & Technology

    2009-09-01

    first statement of work is to determine if high intensity focused ultrasound ( HIFU ) increases the cellular uptake of AS-MDM2, AS-bcl-2 and AS-PKA...Drug Delivery in Prostate Tumor in vivo Using MR Guided Focused Ultrasound (MRg HIFU ). WC, IFMBE Proceedings 25: pp341-344, 2009 6...pharmaceutical agents in the treatment target. In the model system proposed, pulsed high intensity focused ultrasound ( HIFU ) is hypothesized to improve

  18. 76 FR 1598 - Submission for OMB Review; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-11

    ... purpose of the Cell Phone and Debit Card Test is to research alternative survey designs that could....S. Census Bureau. Title: National Survey of Fishing, Hunting, and Wildlife-Associated Recreation... clearance number 1018-0088) the 2011 National Survey of Fishing, Hunting, and Wildlife-Associated Recreation...

  19. 78 FR 70046 - Payment System Risk Policy; Daylight Overdraft Posting Rules

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-22

    ... INFORMATION CONTACT: Jeffrey D. Walker, Assistant Director (202-721-4559) or Michelle D. Olivier, Financial... Telecommunications Device for the Deaf (TDD) only, please call 202-263-4869. SUPPLEMENTARY INFORMATION: Background... debits and credits to institutions' Federal Reserve accounts for different payment types.\\1\\ The...

  20. 31 CFR 598.405 - Transactions incidental to a licensed transaction.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... transaction. 598.405 Section 598.405 Money and Finance: Treasury Regulations Relating to Money and Finance... REGULATIONS Interpretations § 598.405 Transactions incidental to a licensed transaction. Any transaction... transactions by specially designated narcotics traffickers and debits to accounts blocked pursuant to § 598.202...

  1. 31 CFR 598.405 - Transactions incidental to a licensed transaction.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... transaction. 598.405 Section 598.405 Money and Finance: Treasury Regulations Relating to Money and Finance... REGULATIONS Interpretations § 598.405 Transactions incidental to a licensed transaction. Any transaction... transactions by specially designated narcotics traffickers and debits to accounts blocked pursuant to § 598.202...

  2. 31 CFR 598.405 - Transactions incidental to a licensed transaction.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... transaction. 598.405 Section 598.405 Money and Finance: Treasury Regulations Relating to Money and Finance... REGULATIONS Interpretations § 598.405 Transactions incidental to a licensed transaction. Any transaction... transactions by specially designated narcotics traffickers and debits to accounts blocked pursuant to § 598.202...

  3. 31 CFR 598.405 - Transactions incidental to a licensed transaction.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... transaction. 598.405 Section 598.405 Money and Finance: Treasury Regulations Relating to Money and Finance... REGULATIONS Interpretations § 598.405 Transactions incidental to a licensed transaction. Any transaction... transactions by specially designated narcotics traffickers and debits to accounts blocked pursuant to § 598.202...

  4. 31 CFR 598.405 - Transactions incidental to a licensed transaction.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... transaction. 598.405 Section 598.405 Money and Finance: Treasury Regulations Relating to Money and Finance... REGULATIONS Interpretations § 598.405 Transactions incidental to a licensed transaction. Any transaction... transactions by specially designated narcotics traffickers and debits to accounts blocked pursuant to § 598.202...

  5. 37 CFR 202.16 - Preregistration of copyrights.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    .... 202.16 Section 202.16 Patents, Trademarks, and Copyrights COPYRIGHT OFFICE, LIBRARY OF CONGRESS... Open and Maintain a Deposit Account in the Copyright Office,” or write the Register of Copyrights, Copyright Office, Library of Congress, Washington, D.C. 20559. (B) Credit cards, debit cards and electronic...

  6. 37 CFR 202.16 - Preregistration of copyrights.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    .... 202.16 Section 202.16 Patents, Trademarks, and Copyrights COPYRIGHT OFFICE, LIBRARY OF CONGRESS... Open and Maintain a Deposit Account in the Copyright Office,” or write the Register of Copyrights, Copyright Office, Library of Congress, Washington, D.C. 20559. (B) Credit cards, debit cards and electronic...

  7. 31 CFR 585.512 - Transactions relating to travel to or within the FRY (S&M).

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... into or out of the FRY (S&M). (c) This section does not authorize U.S. persons to utilize charge cards, including, but not limited to, debit cards, credit cards or other credit facilities in the FRY (S&M) in...

  8. 31 CFR 370.20 - What requirements apply if I want to authorize a debit entry to my deposit account?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... your deposit account. For a purchase of a book-entry security to be held in an investor account maintained by us, you must be named on the investor account. The authorization must be accomplished only...

  9. 7 CFR 1767.18 - Assets and other debits.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Regulatory Study Costs 182.3Other Regulatory Assets 183Preliminary Survey and Investigation Charges... an experimental status. B. Amounts in this account shall be transferred to Account 101, Electric... considered as experimental. C. The depreciation on property in this account shall be charged to Account 403.8...

  10. 7 CFR 1767.18 - Assets and other debits.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Regulatory Study Costs 182.3Other Regulatory Assets 183Preliminary Survey and Investigation Charges... an experimental status. B. Amounts in this account shall be transferred to Account 101, Electric... considered as experimental. C. The depreciation on property in this account shall be charged to Account 403.8...

  11. 7 CFR 1767.18 - Assets and other debits.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Regulatory Study Costs 182.3Other Regulatory Assets 183Preliminary Survey and Investigation Charges... an experimental status. B. Amounts in this account shall be transferred to Account 101, Electric... considered as experimental. C. The depreciation on property in this account shall be charged to Account 403.8...

  12. 76 FR 29720 - Submission for OMB Review; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-23

    ..., ``Customer Initiated Payments (CIP)'' and RD 1951-66, ``Fedwire Worksheet''. OMB Control Number: 0575-0184... Preauthorized Debits (PAD), Customer Initiated Payments (CIP), and FedWire. These electronic collection methods..., is prepared by the borrower to enroll in CIP. CIP is an electronic collection method that enables...

  13. 30 CFR 220.002 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    .... First level supervisor means an employee whose primary function in NPSL operations is the direct..., geological or other professional skills, and whose primary function in NPSL operations is the handling and... well is non-productive; (2) The balance in the NPSL capital account changes from a debit balance to a...

  14. 31 CFR 370.45 - What is the status of a security if the remittance cannot be collected?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... it has been legally transferred for value to a third person who had no knowledge of the improper debit entry at the time of the transfer. ... SERVICE ELECTRONIC TRANSACTIONS AND FUNDS TRANSFERS RELATING TO UNITED STATES SECURITIES Additional...

  15. Alice in Debitland.

    ERIC Educational Resources Information Center

    Board of Governors of the Federal Reserve System, Washington, DC.

    Designed for the general public and possibly suitable also for high school economics students, this booklet examines the Electronic Fund Transfer Act (EFT), which protects consumers who use debit cards for the electronic transfer of funds. This commercially adapted version of the character in "Alice in Wonderland," uses a story-teller…

  16. High accuracy electronic material level sensor

    DOEpatents

    McEwan, T.E.

    1997-03-11

    The High Accuracy Electronic Material Level Sensor (electronic dipstick) is a sensor based on time domain reflectometry (TDR) of very short electrical pulses. Pulses are propagated along a transmission line or guide wire that is partially immersed in the material being measured; a launcher plate is positioned at the beginning of the guide wire. Reflected pulses are produced at the material interface due to the change in dielectric constant. The time difference of the reflections at the launcher plate and at the material interface are used to determine the material level. Improved performance is obtained by the incorporation of: (1) a high accuracy time base that is referenced to a quartz crystal, (2) an ultrawideband directional sampler to allow operation without an interconnect cable between the electronics module and the guide wire, (3) constant fraction discriminators (CFDs) that allow accurate measurements regardless of material dielectric constants, and reduce or eliminate errors induced by triple-transit or ``ghost`` reflections on the interconnect cable. These improvements make the dipstick accurate to better than 0.1%. 4 figs.

  17. High accuracy electronic material level sensor

    DOEpatents

    McEwan, Thomas E.

    1997-01-01

    The High Accuracy Electronic Material Level Sensor (electronic dipstick) is a sensor based on time domain reflectometry (TDR) of very short electrical pulses. Pulses are propagated along a transmission line or guide wire that is partially immersed in the material being measured; a launcher plate is positioned at the beginning of the guide wire. Reflected pulses are produced at the material interface due to the change in dielectric constant. The time difference of the reflections at the launcher plate and at the material interface are used to determine the material level. Improved performance is obtained by the incorporation of: 1) a high accuracy time base that is referenced to a quartz crystal, 2) an ultrawideband directional sampler to allow operation without an interconnect cable between the electronics module and the guide wire, 3) constant fraction discriminators (CFDs) that allow accurate measurements regardless of material dielectric constants, and reduce or eliminate errors induced by triple-transit or "ghost" reflections on the interconnect cable. These improvements make the dipstick accurate to better than 0.1%.

  18. Design of pulsed guiding magnetic field for high power microwave generators.

    PubMed

    Ju, J-C; Zhang, H; Zhang, J; Shu, T; Zhong, H-H

    2014-09-01

    In this paper, we present a comprehensive study on designing solenoid together with the corresponding power supply system to excite pulsed magnetic field required for high power microwave generators. Particularly, a solenoid is designed and the excited magnetic field is applied to a Ku-band overmoded Cerenkov generator. It is found in experiment that the electron beam is properly guided by the magnetic field and a 1.1 GW high power microwave is achieved at a central frequency of 13.76 GHz. Pulsed solenoid system has the advantages of compactness and low energy consumption, which are of great interest for repetitive operation. The reported studies and results can be generalized to other applications which require magnetic fields.

  19. 17 CFR 256.236 - Taxes accrued.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 17 Commodity and Securities Exchanges 3 2011-04-01 2011-04-01 false Taxes accrued. 256.236 Section... COMPANY ACT OF 1935 7. Current and Accrued Liabilities § 256.236 Taxes accrued. (a) This account shall be credited with the amount of taxes accrued during the accounting period, corresponding debits being made to...

  20. 31 CFR 203.10 - Electronic payment methods.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false Electronic payment methods. 203.10... TAX AND LOAN PROGRAM Electronic Federal Tax Payments § 203.10 Electronic payment methods. (a) General. Electronic payment methods for Federal tax payments available under this subpart include ACH debit entries...

  1. 40 CFR 86.1702-99 - Definitions.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... to a point of first sale in the All States Trading Region. Axle ratio means the number of times the... is below the applicable fleet average NMOG standard, times the applicable production for a given... average NMOG standard, times the applicable production for a given model year. NMOG debits have units of g...

  2. 40 CFR 86.1702-99 - Definitions.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... to a point of first sale in the All States Trading Region. Axle ratio means the number of times the... is below the applicable fleet average NMOG standard, times the applicable production for a given... average NMOG standard, times the applicable production for a given model year. NMOG debits have units of g...

  3. 12 CFR 220.2 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... are subject to contemporaneous exercise if: (1) The amount at risk is held in the account in cash, cash equivalents, or via an escrow receipt; and (2) The transaction is eligible for the cash account by... the customer in a margin account after debiting amounts transferred to the special memorandum account...

  4. 12 CFR 226.8 - Identification of transactions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... either the date of the transaction or the date of debiting the transaction to the consumer's account are... consumer, if the number or symbol reasonably identifies that transaction with that creditor, and if the... the consumer with point-of-sale documentation for that transaction; and (4) the creditor treats an...

  5. The Perceptions and Experiences of Students in a Paperless Accounting Class

    ERIC Educational Resources Information Center

    Teeter, Steve; Madsen, Susan R.; Hughes, Jason; Eagar, Brent

    2007-01-01

    Although financial accounting practices in business have capitalized on the use of technology, this technology has not been fully integrated in higher education for accounting students. While traditional accounting courses laboriously involve rote transcription of debits and credits, educational technology in accounting courses may prove…

  6. 31 CFR 370.21 - Are there any requirements related to a prenotification entry?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... specified time period, we may interpret the nonresponsiveness as the financial institution's agreement to.... In our discretion, we may initiate a prenotification entry to a financial institution prior to... there might be problems with sending a subsequent debit entry. (b) Requirements placed upon financial...

  7. 77 FR 46258 - Debit Card Interchange Fees and Routing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-03

    ... the types of fraud, methods used to commit fraud, and available fraud-prevention methods. An issuer... 920(a)(5) requires the Board to consider (1) the nature, type, and occurrence of fraud in electronic..., merchant trade associations, a card-payment processor, technology companies, a member of Congress...

  8. Credit Cards. Bulletin No. 721. (Revised.)

    ERIC Educational Resources Information Center

    Fox, Linda Kirk

    This cooperative extension bulletin provides basic information about credit cards and their use. It covers the following topics: types of credit cards (revolving credit, travel and entertainment, and debit); factors to consider when evaluating a credit card (interest rates, grace period, and annual membership fee); other credit card costs (late…

  9. 17 CFR 256.188 - Research, development, or demonstration expenditures.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 17 Commodity and Securities Exchanges 3 2011-04-01 2011-04-01 false Research, development, or demonstration expenditures. 256.188 Section 256.188 Commodity and Securities Exchanges SECURITIES AND EXCHANGE... COMPANIES, PUBLIC UTILITY HOLDING COMPANY ACT OF 1935 4. Deferred Debits § 256.188 Research, development, or...

  10. 76 FR 79184 - Agency Information Collection Activities: Announcement of Board Approval Under Delegated...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-21

    ... settlement of electronic debit transactions as the Board considers appropriate and in the public interest. 15... excluded from ``authorization, clearance, and settlement costs.'' In a few instances, the commenters... analysis I. Respondent Information The Board proposed to have respondents provide the name of the card...

  11. Coming Soon: The Cashless Campus.

    ERIC Educational Resources Information Center

    Peskin, Carole Ann; McDemmond, Marie

    1994-01-01

    Increasing use of credit on college campuses raises important policy questions and planning needs. Credit and debit card use varies, and most institutions are studying, experimenting, and inventing uses. Although use of credit improves cash flow, streamlines payments and services, and increases income, there are also costs to the institution. (MSE)

  12. 76 FR 13976 - Notice of Request for Revision of a Currently Approved Information Collection

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-15

    .... SUPPLEMENTARY INFORMATION: Title: Form RD 1951-65, Customer Initiated Payments (CIP) Enrollment Form; Form RD... Initiated Payments [CIP], FedWire, and Preauthorized Debits [PAD]) for receiving and processing loan... approved forms for collecting bank routing information for CIP, FedWire, and PAD. Estimate of Burden...

  13. 12 CFR 235.2 - Definitions.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Banking FEDERAL RESERVE SYSTEM (CONTINUED) BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM (CONTINUED... transactions over a payment card network. An acquirer does not include a person that acts only as a processor... management or policies of the company, as the Board determines. (f) Debit card (1) Means any card, or other...

  14. 12 CFR 235.2 - Definitions.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Banking FEDERAL RESERVE SYSTEM (CONTINUED) BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM (CONTINUED... transactions over a payment card network. An acquirer does not include a person that acts only as a processor... management or policies of the company, as the Board determines. (f) Debit card (1) Means any card, or other...

  15. 12 CFR 235.2 - Definitions.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Banking FEDERAL RESERVE SYSTEM (CONTINUED) BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM (CONTINUED... transactions over a payment card network. An acquirer does not include a person that acts only as a processor... management or policies of the company, as the Board determines. (f) Debit card (1) Means any card, or other...

  16. 77 FR 22666 - Payment System Risk Policy; Daylight Overdraft Posting Rules

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-17

    ... of separately-sorted savings bonds and to eliminate a reference to the contractual clearing balance... clearing balance program are effective July 12, 2012. FOR FURTHER INFORMATION CONTACT: Susan V. Foley... account balances according to a set of ``posting rules'' that determine the intraday timing of debits and...

  17. 31 CFR 203.10 - Electronic payment methods.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 31 Money and Finance:Treasury 2 2012-07-01 2012-07-01 false Electronic payment methods. 203.10... TAX AND LOAN PROGRAM Electronic Federal Tax Payments § 203.10 Electronic payment methods. (a) General. Electronic payment methods for Federal tax payments available under this subpart include ACH debit entries...

  18. 31 CFR 203.10 - Electronic payment methods.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 31 Money and Finance:Treasury 2 2011-07-01 2011-07-01 false Electronic payment methods. 203.10... TAX AND LOAN PROGRAM Electronic Federal Tax Payments § 203.10 Electronic payment methods. (a) General. Electronic payment methods for Federal tax payments available under this subpart include ACH debit entries...

  19. 31 CFR 203.10 - Electronic payment methods.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 31 Money and Finance: Treasury 2 2014-07-01 2014-07-01 false Electronic payment methods. 203.10... TAX AND LOAN PROGRAM Electronic Federal Tax Payments § 203.10 Electronic payment methods. (a) General. Electronic payment methods for Federal tax payments available under this subpart include ACH debit entries...

  20. 31 CFR 203.10 - Electronic payment methods.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 31 Money and Finance:Treasury 2 2013-07-01 2013-07-01 false Electronic payment methods. 203.10... TAX AND LOAN PROGRAM Electronic Federal Tax Payments § 203.10 Electronic payment methods. (a) General. Electronic payment methods for Federal tax payments available under this subpart include ACH debit entries...

  1. 76 FR 57907 - Indorsement and Payment of Checks Drawn on the United States Treasury

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-19

    ... Checks Drawn on the United States Treasury AGENCY: Financial Management Service, Fiscal Service, Treasury...), Financial Management Service (FMS), to direct Federal Reserve Banks to debit a financial institution's... the Treasury (Treasury), Financial Management Service (FMS),\\1\\ is amending its regulation at 31 CFR...

  2. 47 CFR 32.4320 - Unamortized operating investment tax credits-net.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 2 2010-10-01 2010-10-01 false Unamortized operating investment tax credits... Sheet Accounts § 32.4320 Unamortized operating investment tax credits—net. (a) This account shall be credited and Account 7210, Operating Investment Tax Credits—Net, should be debited with investment tax...

  3. 47 CFR 32.4330 - Unamortized nonoperating investment tax credits-net.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 2 2010-10-01 2010-10-01 false Unamortized nonoperating investment tax credits... Sheet Accounts § 32.4330 Unamortized nonoperating investment tax credits—net. (a) This account shall be credited and Account 7400, Nonoperating Taxes, shall be debited with investment tax credits generated from...

  4. 7 CFR 1767.18 - Assets and other debits.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Regulatory Study Costs 182.3Other Regulatory Assets 183Preliminary Survey and Investigation Charges.... This account shall include the cost of electric plant which was constructed as a research, development..., is designed to consist of two or more units or circuits which may be placed in service at different...

  5. 17 CFR 256.188 - Research, development, or demonstration expenditures.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Research, development, or... COMPANIES, PUBLIC UTILITY HOLDING COMPANY ACT OF 1935 4. Deferred Debits § 256.188 Research, development, or... of all expenditures for research, development or demonstration undertaken by or sponsored through the...

  6. Technology-Driven Resource Sharing: Paying for Improvement.

    ERIC Educational Resources Information Center

    Rush, James E.

    1993-01-01

    Addresses the inadequacies of traditional methods of library financing and proposes a strategy to be implemented in an environment supported by automation and networks. Publisher pricing of data rather than publications, options for charging library users with debit cards, and the role of regional library networks are discussed. (EAM)

  7. 75 FR 81721 - Debit Card Interchange Fees and Routing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-28

    ... may be processed and from inhibiting the ability of a merchant to direct the routing of an electronic... alternatives, the issuers and networks would be prohibited from inhibiting a merchant's ability to direct the... restrictions, card-issuing arrangements, and incentive programs for both merchants and issuers. Interested...

  8. 17 CFR 256.411 - Provision for deferred income taxes-credit.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... taxes-credit. 256.411 Section 256.411 Commodity and Securities Exchanges SECURITIES AND EXCHANGE... deferred income taxes—credit. This account shall be credited and Accumulated Deferred Income Taxes debited with an amount equal to the portion of taxes on income payable for the year which is attributable to a...

  9. 17 CFR 256.255 - Accumulated deferred investment tax credits.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... investment tax credits. 256.255 Section 256.255 Commodity and Securities Exchanges SECURITIES AND EXCHANGE... investment tax credits. (a) This account shall be credited and account 411.5, Investment tax credit, debited with investment tax credits deferred by companies which do not apply such credits as a reduction of the...

  10. Coupling of laser energy into plasma channels

    NASA Astrophysics Data System (ADS)

    Dimitrov, D. A.; Giacone, R. E.; Bruhwiler, D. L.; Busby, R.; Cary, J. R.; Geddes, C. G. R.; Esarey, E.; Leemans, W. P.

    2007-04-01

    Diffractive spreading of a laser pulse imposes severe limitations on the acceleration length and maximum electron energy in the laser wake field accelerator (LWFA). Optical guiding of a laser pulse via plasma channels can extend the laser-plasma interaction distance over many Rayleigh lengths. Energy efficient coupling of laser pulses into and through plasma channels is very important for optimal LWFA performance. Results from simulation parameter studies on channel guiding using the particle-in-cell (PIC) code VORPAL [C. Nieter and J. R. Cary, J. Comput. Phys. 196, 448 (2004)] are presented and discussed. The effects that density ramp length and the position of the laser pulse focus have on coupling into channels are considered. Moreover, the effect of laser energy leakage out of the channel domain and the effects of tunneling ionization of a neutral gas on the guided laser pulse are also investigated. Power spectral diagnostics were developed and used to separate pump depletion from energy leakage. The results of these simulations show that increasing the density ramp length decreases the efficiency of coupling a laser pulse to a channel and increases the energy loss when the pulse is vacuum focused at the channel entrance. Then, large spot size oscillations result in increased energy leakage. To further analyze the coupling, a differential equation is derived for the laser spot size evolution in the plasma density ramp and channel profiles are simulated. From the numerical solution of this equation, the optimal spot size and location for coupling into a plasma channel with a density ramp are determined. This result is confirmed by the PIC simulations. They show that specifying a vacuum focus location of the pulse in front of the top of the density ramp leads to an actual focus at the top of the ramp due to plasma focusing, resulting in reduced spot size oscillations. In this case, the leakage is significantly reduced and is negligibly affected by ramp length, allowing for efficient use of channels with long ramps.

  11. Faraday spectroscopy of ultracold atoms guided in hollow core optical fibers

    NASA Astrophysics Data System (ADS)

    Fatemi, Fredrik; Pechkis, Joseph

    2013-05-01

    We have performed spatially and temporally resolved magnetometry using Faraday spectroscopy of ultracold rubidium atoms confined in hollow core optical fibers. We first guide 105 Rb atoms into a 3-cm-long, 100-micron-core hollow fiber using blue-detuned hollow waveguide modes. Inside the fiber, the atoms are exposed to an optical pumping pulse, and the Larmor precession is monitored by the polarization rotation of a probe laser beam detuned by 50 GHz. The intense guide beams can perturb the detected Larmor precession frequencies, but we show that by confining the atoms to the intensity null of higher order blue-detuned hollow modes, these perturbations are reduced by over 95% compared to red-detuned guides. By adjusting the guide beam detuning and polarization, the deleterious effects of both photon scattering and frequency shifts can be suppressed such that multiple magnetic field measurements with sensitivity of 30 nT per sampling pulse can be obtained throughout the length of the fiber in a single loading cycle. Work supported by ONR and DARPA.

  12. Pulse cleaning flow models and numerical computation of candle ceramic filters.

    PubMed

    Tian, Gui-shan; Ma, Zhen-ji; Zhang, Xin-yi; Xu, Ting-xiang

    2002-04-01

    Analytical and numerical computed models are developed for reverse pulse cleaning system of candle ceramic filters. A standard turbulent model is demonstrated suitably to the designing computation of reverse pulse cleaning system from the experimental and one-dimensional computational result. The computed results can be used to guide the designing of reverse pulse cleaning system, which is optimum Venturi geometry. From the computed results, the general conclusions and the designing methods are obtained.

  13. INTERNATIONAL CONFERENCE ON SEMICONDUCTOR INJECTION LASERS SELCO-87: Behavior of gain-guided lasers generating high-power nanosecond pulses

    NASA Astrophysics Data System (ADS)

    Erbert, G.

    1988-11-01

    Computer-controlled apparatus was used in an investigation of gain-guided narrow-stripe AlGaAs double heterostructure lasers. These lasers were excited with current pulses of 10 ns duration and amplitudes up to 3 A. The watt-ampere characteristics together with near- and far-field radiation patterns were considered using an analytic model of the lasers. The results showed that the values of the gain under a stripe contact or of the absorption outside this region varied with the output power.

  14. High-Altitude Electromagnetic Pulse (HEMP) Testing

    DTIC Science & Technology

    2011-11-10

    Security Classification Guide ( SCG ). b. The HEMP simulation facility shall have a measured map of the peak amplitude waveform of the...Quadripartite Standardization Agreement s, sec second SCG security classification guide SN serial number SOP Standard Operating Procedure

  15. Enhanced thermal stability of silica-coated gold nanorods for photoacoustic imaging and image-guided therapy.

    PubMed

    Chen, Yun-Sheng; Frey, Wolfgang; Kim, Seungsoo; Homan, Kimberly; Kruizinga, Pieter; Sokolov, Konstantin; Emelianov, Stanislav

    2010-04-26

    Photothermal stability and, therefore, consistency of both optical absorption and photoacoustic response of the plasmonic nanoabsorbers is critical for successful photoacoustic image-guided photothermal therapy. In this study, silica-coated gold nanorods were developed as a multifunctional molecular imaging and therapeutic agent suitable for image-guided photothermal therapy. The optical properties and photothermal stability of silica-coated gold nanorods under intense irradiation with nanosecond laser pulses were investigated by UV-Vis spectroscopy and transmission electron microscopy. Silica-coated gold nanorods showed increased photothermal stability and retained their superior optical properties under much higher fluences. The changes in photoacoustic response of PEGylated and silica-coated nanorods under laser pulses of various fluences were compared. The silica-coated gold nanorods provide a stable photoacoustic signal, which implies better imaging capabilities and make silica-coated gold nanorods a promising imaging and therapeutic nano-agent for photoacoustic imaging and image-guided photothermal therapy.

  16. Enhanced thermal stability of silica-coated gold nanorods for photoacoustic imaging and image-guided therapy

    PubMed Central

    Chen, Yun-Sheng; Frey, Wolfgang; Kim, Seungsoo; Homan, Kimberly; Kruizinga, Pieter; Sokolov, Konstantin; Emelianov, Stanislav

    2010-01-01

    Photothermal stability and, therefore, consistency of both optical absorption and photoacoustic response of the plasmonic nanoabsorbers is critical for successful photoacoustic image-guided photothermal therapy. In this study, silica-coated gold nanorods were developed as a multifunctional molecular imaging and therapeutic agent suitable for image-guided photothermal therapy. The optical properties and photothermal stability of silica-coated gold nanorods under intense irradiation with nanosecond laser pulses were investigated by UV-Vis spectroscopy and transmission electron microscopy. Silica-coated gold nanorods showed increased photothermal stability and retained their superior optical properties under much higher fluences. The changes in photoacoustic response of PEGylated and silica-coated nanorods under laser pulses of various fluences were compared. The silica-coated gold nanorods provide a stable photoacoustic signal, which implies better imaging capabilities and make silica-coated gold nanorods a promising imaging and therapeutic nano-agent for photoacoustic imaging and image-guided photothermal therapy. PMID:20588732

  17. Effects of nanomaterial saturable absorption on gain-guide soliton in a positive group-dispersion fiber laser: Simulations and experiments

    NASA Astrophysics Data System (ADS)

    Du, Tuanjie; Wan, Xiaojiao; Yang, Runhua; Li, Weiwei; Ruan, Qiujun; Chen, Nan; Luo, Zhengqian

    2018-01-01

    In recent years, several kinds of nanomaterials have been discovered, and successfully used as saturable absorbers (SAs) for passively mode-locked fiber lasers. However, it is found that most of nanomaterials-based SAs cannot stably generate gain-guide solitons in positive group-dispersion fiber lasers, which is urgently expected to fully understand the inherent reasons. In this paper, we numerically and experimentally investigate the effects of nanomaterial saturable absorption (e.g. modulation depth and saturation optical power) on gain-guide soliton in positive group-dispersion Er3+-doped fiber laser (PGD-EDFL). By numerically solving the Ginzburg-Landau equation, the evolutions of both the mode-locked optical spectrum and pulse duration as a function of modulation depth and saturation optical power are analyzed, respectively. In experiment, we firstly prepare five nanomaterial SAs with the similar insertion loss, which have the different modulation depth from 1.80% to 23.36%, and the different saturation optical power from 8.8 to 536 W. We then perform the experimental comparison by incorporating the five SAs in a same PGD-EDFL cavity, respectively. The experimental results are in good agreement with the numerical ones. Our result reveals that: (1) a low modulation depth cannot support the formation of gain-guide soliton, (2) as the modulation depth increases, the spectral bandwidth of gain-guide soliton increases, the pulse duration decreases and the pulse chirp becomes large, (3) the saturation optical power has the weak influences on the gain-guide soliton performances.

  18. Filtering of higher-order laser modes using plasma structures

    NASA Astrophysics Data System (ADS)

    Djordjevic, Blagoje; Benedetti, Carlo; Schroeder, Carl; Esarey, Eric; Leemans, Wim

    2017-10-01

    Plasma structures based on leaky channels are proposed to filter higher-order laser mode content. The evolution and propagation of non-Gaussian laser pulses in leaky channels is studied, and it is shown that, for appropriate laser-plasma parameters, the higher-order laser mode content may be removed while the fundamental mode remains well-guided. The behavior of the multi-mode laser pulse is described analytically, including the derivation of the leakage coefficients, and compared to numerical calculations. Gaussian laser pulse propagation, without higher-order mode content, improves guiding in parabolic plasma channels, enabling extended interaction lengths for laser-plasma accelerator applications. This work was supported by the Director, Office of Science, Office of High Energy Physics, of the U.S. Department of Energy under Contract No. DE-AC02-05CH11231.

  19. HV discharge acceleration by sequences of UV laser filaments with visible and near-infrared pulses

    NASA Astrophysics Data System (ADS)

    Schubert, Elise; Rastegari, Ali; Feng, Chengyong; Mongin, Denis; Kamer, Brian; Kasparian, Jérôme; Wolf, Jean-Pierre; Arissian, Ladan; Diels, Jean-Claude

    2017-12-01

    We investigate the triggering and guiding of DC high-voltage discharges over a distance of 37 cm by filaments produced by ultraviolet (266 nm) laser pulses of 200 ps duration. The latter reduce the breakdown electric field by half and allow up to 80% discharge probability in an electric field of 920 kV m–1. This high efficiency is not further increased by adding nanosecond pulses in the Joule range at 532 and at 1064 nm. However, the latter statistically increases the guiding length, thereby accelerating the discharge by a factor of 2. This effect is due both to photodetachment and to the heating of the plasma channel, that increases the efficiency of avalanche ionization and reduces electron attachment and recombination.

  20. PPM-based System for Guided Waves Communication Through Corrosion Resistant Multi-wire Cables

    NASA Astrophysics Data System (ADS)

    Trane, G.; Mijarez, R.; Guevara, R.; Pascacio, D.

    Novel wireless communication channels are a necessity in applications surrounded by harsh environments, for instance down-hole oil reservoirs. Traditional radio frequency (RF) communication schemes are not capable of transmitting signals through metal enclosures surrounded by corrosive gases and liquids. As an alternative to RF, a pulse position modulation (PPM) guided waves communication system has been developed and evaluated using a corrosion resistant 4H18 multi-wire cable, commonly used to descend electronic gauges in down-hole oil applications, as the communication medium. The system consists of a transmitter and a receiver that utilizes a PZT crystal, for electrical/mechanical coupling, attached to each extreme of the multi-wire cable. The modulator is based on a microcontroller, which transmits60 kHz guided wave pulses, and the demodulator is based on a commercial digital signal processor (DSP) module that performs real time DSP algorithms. Experimental results are presented, which were obtained using a 1m corrosion resistant 4H18multi-wire cable, commonly used with downhole electronic gauges in the oil sector. Although there was significant dispersion and multiple mode excitations of the transmitted guided wave energy pulses, the results show that data rates on the order of 500 bits per second are readily available employing PPM and simple communications techniques.

  1. 26 CFR 301.6311-2 - Payment by credit card and debit card.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... business and is not returned pursuant to paragraph (d)(3) of this section. (c) Payment not made—(1... required to be returned pursuant to paragraph (d)(3) of this section. This continuing liability of the.... (3) Return of funds pursuant to error resolution procedures. Notwithstanding section 6402, if a...

  2. 17 CFR 256.411.5 - Investment tax credit.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Investment tax credit. 256.411... HOLDING COMPANY ACT OF 1935 Income and Expense Accounts § 256.411.5 Investment tax credit. (a) This account shall be debited with the amounts of investment tax credits related to service company property...

  3. 17 CFR 256.411.5 - Investment tax credit.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 17 Commodity and Securities Exchanges 3 2011-04-01 2011-04-01 false Investment tax credit. 256.411... HOLDING COMPANY ACT OF 1935 Income and Expense Accounts § 256.411.5 Investment tax credit. (a) This account shall be debited with the amounts of investment tax credits related to service company property...

  4. 77 FR 24667 - TANF Assistance and Electronic Benefit Transfer Transactions; Request for Public Comment

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-25

    ... Family Assistance (OFA) is interested in learning about how States deliver Temporary Assistance to Needy... types of restrictions on assistance usage. OFA also is interested in learning about States' current... as ``the use of a credit or debit card service, automated teller machine, point-of-sale terminal, or...

  5. 75 FR 80102 - Self-Regulatory Organizations; The NASDAQ Stock Market LLC; Notice of Filing and Immediate...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-21

    ... have run and/or all appeal timeframes are exhausted. With respect to non-disciplinary actions, the... all appeal timeframes are exhausted. Any uncontested disciplinary or non- disciplinary actions will be... 8310, 8320 or 8330. With respect to disciplinary sanctions, the Exchange would not debit any monies...

  6. 47 CFR 64.1504 - Restrictions on the use of toll-free numbers.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ..., debit, prepaid account, phone bill, or credit or calling card and, if a subscriber elects to pay by means of phone bill, a clear explanation that the subscriber will be assessed for calls made to the information service from the subscriber's phone line; (vii) A unique personal identification number or other...

  7. 18 CFR 367.1890 - Account 189, Unamortized loss on reacquired debt.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... POWER ACT AND NATURAL GAS ACT Balance Sheet Chart of Accounts Deferred Debits § 367.1890 Account 189... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Account 189, Unamortized loss on reacquired debt. 367.1890 Section 367.1890 Conservation of Power and Water Resources...

  8. 76 FR 75570 - Self-Regulatory Organizations; The Depository Trust Company; Notice of Filing of Proposed Rule...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-02

    ... counterparty by counterparty basis. Currently, all free money market instrument (``MMI'') deliveries are routed... was built in 1990 to route money market instrument (``MMI'') transactions for receiver approval. In... orders involve no securities, only money. \\5\\ The net debit cap control is designed so that DTC may...

  9. 75 FR 4100 - Enterprise Income Verification (EIV) System-Debts Owed to PHAs and Terminations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-26

    ... Paperwork Reduction Act. The Department is soliciting public comments on the subject proposal. This information collection is required to identify families who no longer participate in a HUD rental assistance program due to adverse termination of tenancy and/or assistance, land owe a debit to a Public Housing...

  10. 17 CFR 240.10b-16 - Disclosure of credit terms in margin transactions.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... EXCHANGE COMMISSION (CONTINUED) GENERAL RULES AND REGULATIONS, SECURITIES EXCHANGE ACT OF 1934 Rules and... determining the debit balance or balances on which interest is to be charged and whether credit is to be given for credit balances in cash accounts; (vi) what other charges resulting from the extension of credit...

  11. 31 CFR 203.19 - Sources of balances.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 31 Money and Finance:Treasury 2 2011-07-01 2011-07-01 false Sources of balances. 203.19 Section... § 203.19 Sources of balances. A financial institution must be a collector depositary that accepts term... TIP main account balance pursuant to subpart C of this part; (b) EFTPS ACH credit and debit...

  12. 31 CFR 203.19 - Sources of balances.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false Sources of balances. 203.19 Section... § 203.19 Sources of balances. A financial institution must be a collector depositary that accepts term... TIP main account balance pursuant to subpart C of this part; (b) EFTPS ACH credit and debit...

  13. 31 CFR 587.505 - Entries in certain accounts for normal service charges authorized.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... charges authorized. (a) A U.S. financial institution is authorized to debit any blocked account held at that financial institution in payment or reimbursement for normal service charges owed it by the owner of that blocked account. (b) As used in this section, the term normal service charge shall include...

  14. Effects of Simulation to Teach Students with Disabilities Basic Finance Skills

    ERIC Educational Resources Information Center

    Rowe, Dawn A.; Test, David W.

    2013-01-01

    This study used a multiple probe design across participants to examine the effects of classroom simulation using static picture prompts to teach students to make a purchase using a debit card and track expenses by subtracting purchase amounts and adding deposits into a check register. Results demonstrated a functional relation between simulated…

  15. 18 CFR 367.105 - Accounts 411.4, and 411.5, Investment tax credit adjustments.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ....5, Investment tax credit adjustments. 367.105 Section 367.105 Conservation of Power and Water... tax credit adjustments. (a) Account 411.4 (§ 367.4114) must be debited with the amounts of investment tax credits related to service company property that are credited to account 255, Accumulated deferred...

  16. 78 FR 72016 - User Fees for Processing Installment Agreements and Offers in Compromise

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-02

    ... regulations affect taxpayers who wish to pay their federal tax liabilities through installment agreements and... to pay $43 for any new installment agreement, including a direct debit installment agreement. The... do not have the means to pay the user fee, even at the reduced rate. The commenter stated that low...

  17. 78 FR 25496 - Self-Regulatory Organizations; National Securities Clearing Corporation; Notice of Filing of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-01

    ... obligations to its Members in the event of the default of the Member or family of affiliated Members (``Affiliated Family'') that would generate the largest aggregate payment obligation to NSCC in stressed... Members and Affiliated Families that regularly incur the largest gross settlement debits over a settlement...

  18. Turning a Private Label Bank Card into a Multi-function Campus ID Card.

    ERIC Educational Resources Information Center

    James, Thomas G.; Norwood, Bill R.

    1991-01-01

    This article describes the development at Florida State University of the Seminole ACCESS card, which functions simultaneously as a bank automated teller machine card, a student identification card, and a debit card. Explained are the partnership between the university and the bank charge card center, funding system, technologies involved, and…

  19. Designing an ultrafast laser virtual laboratory using MATLAB GUIDE

    NASA Astrophysics Data System (ADS)

    Cambronero-López, F.; Gómez-Varela, A. I.; Bao-Varela, C.

    2017-05-01

    In this work we present a virtual simulator developed using the MATLAB GUIDE environment based on the numerical resolution of the nonlinear Schrödinger equation (NLS) and using the split step method for the study of the spatial-temporal propagation of nonlinear ultrashort laser pulses. This allows us to study the spatial-temporal propagation of ultrafast pulses as well as the influence of high-order spectral phases such as group delay dispersion and third-order dispersion on pulse compression in time. The NLS can describe several nonlinear effects, in particular in this paper we consider the Kerr effect, cross-polarized wave generation and cubic-quintic propagation in order to highlight the potential of this equation combined with the GUIDE environment. Graphical user interfaces are commonly used in science and engineering teaching due to their educational value, and have proven to be an effective way to engage and motivate students. Specifically, the interactive graphical interfaces presented provide the visualization of some of the most important nonlinear optics phenomena and allows users to vary the values of the main parameters involved.

  20. New Pulsed Cold Neutron Beam Line for Fundamental Nuclear Physics at LANSCE.

    PubMed

    Seo, P-N; Bowman, J D; Gericke, M; Gillis, R C; Greene, G L; Leuschner, M B; Long, J; Mahurin, R; Mitchell, G S; Penttila, S I; Peralta, G; Sharapov, E I; Wilburn, W S

    2005-01-01

    The NPDGamma collaboration has completed the construction of a pulsed cold neutron beam line on flight path12 at the Los Alamos Neutron Science Center (LANSCE). We describe the new beam line and characteristics of the beam. We report results of the moderator brightness and the guide performance measurements. FP12 has the highest pulsed cold neutron intensity for nuclear physics in the world.

  1. Computerized tomography-guided sphenopalatine ganglion pulsed radiofrequency treatment in 16 patients with refractory cluster headaches: Twelve- to 30-month follow-up evaluations.

    PubMed

    Fang, Luo; Jingjing, Lu; Ying, Shen; Lan, Meng; Tao, Wang; Nan, Ji

    2016-02-01

    Sphenopalatine ganglion percutaneous radiofrequency thermocoagulation treatment can improve the symptoms of cluster headaches to some extent. However, as an ablation treatment, radiofrequency thermocoagulation treatment also has side effects. To preliminarily evaluate the efficacy and safety of a non-ablative computerized tomography-guided pulsed radiofrequency treatment of sphenopalatine ganglion in patients with refractory cluster headaches. We included and analysed 16 consecutive cluster headache patients who failed to respond to conservative therapy from the Pain Management Center at the Beijing Tiantan Hospital between April 2012 and September 2013 treated with pulsed radiofrequency treatment of sphenopalatine ganglion. Eleven of 13 episodic cluster headaches patients and one of three chronic cluster headaches patient were completely relieved of the headache within an average of 6.3 ± 6.0 days following the treatment. Two episodic cluster headache patients and two chronic cluster headache patients showed no pain relief following the treatment. The mean follow-up time was 17.0 ± 5.5 months. All patients enrolled in this study showed no treatment-related side effects or complications. Our data show that patients with refractory episodic cluster headaches were quickly, effectively and safely relieved from the cluster period after computerized tomography-guided pulsed radiofrequency treatment of sphenopalatine ganglion, suggesting that it may be a therapeutic option if conservative treatments fail. © International Headache Society 2015.

  2. Sex Differences in Cardiovascular and Subjective Stress Reactions: Prospective Evidence in a Realistic Military Setting

    DTIC Science & Technology

    2014-01-01

    procedures were held constant). After the period of quiet rest, the finger pulse oximeter (MedSource International, Mound, MN) was applied to the left...temperature were then recorded with pulse oximeter (Medline Industries, Inc., Mundelein, IL). Following standard guide- lines (Pickering et al., 2005

  3. 38 CFR 36.4202 - Definitions.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... § 36.4202 Definitions. Wherever used in 38 U.S.C. 3712 or the § 36.4200 series, unless the context... § 36.4200 series, which have been paid and debited to the loan account. Unpaid late charges may not be included in the indebtedness. Lender. The payee or assignee or transferee of an obligation at the time it...

  4. 38 CFR 36.4202 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... § 36.4202 Definitions. Wherever used in 38 U.S.C. 3712 or the § 36.4200 series, unless the context... § 36.4200 series, which have been paid and debited to the loan account. Unpaid late charges may not be included in the indebtedness. Lender. The payee or assignee or transferee of an obligation at the time it...

  5. Defense Logistics Agency Disposition Services Afghanistan Disposal Process Needed Improvement

    DTIC Science & Technology

    2013-11-08

    audit, and management was proactive in correcting the deficiencies we identified. DLA DS eliminated backlogs, identified and corrected system ...problems, provided additional system training, corrected coding errors, added personnel to key positions, addressed scale issues, submitted debit...Service Automated Information System to the Reutilization Business Integration2 (RBI) solution. The implementation of RBI in Afghanistan occurred in

  6. 50 CFR Table 1b to Part 679 - Discard and Disposition Codes1

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Confiscation or seized 63 Deadloss (crab only) 79 Overage 62 Retained for future sale 87 Tagged IFQ Fish (Exempt from debit) 64 Whole fish/bait, not sold. Used as bait onboard vessel 92 Whole fish/bait, sold 61 Whole fish/discard at sea. Whole groundfish and prohibited species discarded by catcher vessels, catcher...

  7. 50 CFR Table 1b to Part 679 - Discard and Disposition Codes1

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Confiscation or seized 63 Deadloss (crab only) 79 Overage 62 Retained for future sale 87 Tagged IFQ Fish (Exempt from debit) 64 Whole fish/bait, not sold. Used as bait onboard vessel 92 Whole fish/bait, sold 61 Whole fish/discard at sea. Whole groundfish and prohibited species discarded by catcher vessels, catcher...

  8. 50 CFR Table 1b to Part 679 - Discard and Disposition Codes1

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Confiscation or seized 63 Deadloss (crab only) 79 Overage 62 Retained for future sale 87 Tagged IFQ Fish (Exempt from debit) 64 Whole fish/bait, not sold. Used as bait onboard vessel 92 Whole fish/bait, sold 61 Whole fish/discard at sea. Whole groundfish and prohibited species discarded by catcher vessels, catcher...

  9. 50 CFR Table 1b to Part 679 - Discard and Disposition Codes1

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Confiscation or seized 63 Deadloss (crab only) 79 Overage 62 Retained for future sale 87 Tagged IFQ Fish (Exempt from debit) 64 Whole fish/bait, not sold. Used as bait onboard vessel 92 Whole fish/bait, sold 61 Whole fish/discard at sea. Whole groundfish and prohibited species discarded by catcher vessels, catcher...

  10. 31 CFR 548.409 - Credit extended and cards issued by U.S. financial institutions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Credit extended and cards issued by U... SANCTIONS REGULATIONS Interpretations § 548.409 Credit extended and cards issued by U.S. financial..., charge cards, debit cards, or other credit facilities issued by a U.S. financial institution to a person...

  11. 31 CFR 588.409 - Credit extended and cards issued by U.S. financial institutions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Credit extended and cards issued by U... BALKANS STABILIZATION REGULATIONS Interpretations § 588.409 Credit extended and cards issued by U.S... not limited to, charge cards, debit cards, or other credit facilities issued by a U.S. financial...

  12. 31 CFR 598.409 - Credit extended and cards issued by U.S. financial institutions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Credit extended and cards issued by U... NARCOTICS KINGPIN SANCTIONS REGULATIONS Interpretations § 598.409 Credit extended and cards issued by U.S... existing credit agreements, including, but not limited to, charge cards, debit cards, or other credit...

  13. 31 CFR 593.409 - Credit extended and cards issued by U.S. financial institutions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Credit extended and cards issued by U... LIBERIAN REGIME OF CHARLES TAYLOR SANCTIONS REGULATIONS Interpretations § 593.409 Credit extended and cards..., including, but not limited to, charge cards, debit cards, or other credit facilities issued by a U.S...

  14. 31 CFR 544.409 - Credit extended and cards issued by U.S. financial institutions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Credit extended and cards issued by U... agreements, including, but not limited to, charge cards, debit cards, or other credit facilities issued by a... OF MASS DESTRUCTION PROLIFERATORS SANCTIONS REGULATIONS Interpretations § 544.409 Credit extended and...

  15. 31 CFR 594.410 - Credit extended and cards issued by U.S. financial institutions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Credit extended and cards issued by U... TERRORISM SANCTIONS REGULATIONS Interpretations § 594.410 Credit extended and cards issued by U.S. financial... agreements, including, but not limited to, charge cards, debit cards, or other credit facilities issued by a...

  16. 31 CFR 542.409 - Credit extended and cards issued by U.S. financial institutions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Credit extended and cards issued by U... SANCTIONS REGULATIONS Interpretations § 542.409 Credit extended and cards issued by U.S. financial..., charge cards, debit cards, or other credit facilities issued by a U.S. financial institution to a person...

  17. 31 CFR 547.409 - Credit extended and cards issued by U.S. financial institutions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Credit extended and cards issued by U... DEMOCRATIC REPUBLIC OF THE CONGO SANCTIONS REGULATIONS Interpretations § 547.409 Credit extended and cards..., including, but not limited to, charge cards, debit cards, or other credit facilities issued by a U.S...

  18. 31 CFR 536.409 - Credit extended and cards issued by U.S. financial institutions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Credit extended and cards issued by U... NARCOTICS TRAFFICKING SANCTIONS REGULATIONS Interpretations § 536.409 Credit extended and cards issued by U... any existing credit agreements, including, but not limited to, charge cards, debit cards, or other...

  19. 17 CFR 256.255 - Accumulated deferred investment tax credits.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... overall income tax expense in the year in which a tax credit is realized. A proportionate amount shall be debited to account 411.5, Investment tax credit, as determined in relation to the average useful life of... investment tax credits for each year with the weighted-average service life of such properties and any unused...

  20. 12 CFR Appendix D to Part 360 - Sweep/Automated Credit Account File Structure

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... record should be used for each instance where funds affiliated with the deposit account are held in an... field used to identify the account from which funds are swept or debited. The field may be the Account... Account Identifier—2If necessary, the second element used to identify the account from which funds are...

  1. 77 FR 3531 - Self-Regulatory Organizations; The Depository Trust Company; Order Approving Proposed Rule Change...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-24

    ... deliveries bypass RAD on a counterparty by counterparty basis. Currently, all free money market instrument... Participant before its account is updated. The RAD function was built in 1990 to route money market instrument... premiums. Payment orders involve no securities, only money. \\6\\ The net debit cap control is designed so...

  2. 45 CFR 158.241 - Form of rebate.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... check or lump-sum reimbursement using the same method that was used for payment, such as credit card or... in the form of a premium credit, lump-sum check, or, if an enrollee paid the premium using a credit card or direct debit, by lump-sum reimbursement to the account used to pay the premium. (2) Any rebate...

  3. 75 FR 48306 - Proposed Information Collection; Comment Request; National Survey of Fishing, Hunting, and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-10

    ...; National Survey of Fishing, Hunting, and Wildlife-Associated Recreation (FHWAR) Cell Phone and Debit Card... operation. The first panel will receive an advance letter with a prepaid cell phone. The advance letter will request that a household member call the telephone center and complete an interview using the cell phone...

  4. 31 CFR 540.504 - Entries in certain accounts for normal service charges authorized.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Statements of Licensing Policy § 540.504 Entries in certain accounts for normal service charges authorized. (a) A U.S. financial institution is authorized to debit any blocked account held by that financial institution in payment or reimbursement for normal service charges owed to it by the owner of the blocked...

  5. 77 FR 3833 - Self-Regulatory Organizations; The Depository Trust Company; Order Approving Proposed Rule Change...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-25

    ... To Mitigate Systemic Risk, Specifically Liquidity Related, Associated With DTC End of Day Net Funds... weekend or holiday). In doing so, DTC believes it would reduce the systemic risk associated with a... systemic risk due to Participant failure. \\5\\ These net debit caps are supported by $3.2 billion of...

  6. Admin on the Fly

    ERIC Educational Resources Information Center

    Raths, David

    2009-01-01

    Students at Tompkins Cortland Community College (commonly known as TC3) in upstate New York can use mobile phones to check their grades and course schedules, sign up for text alerts about class cancellations, and view a campus weather cam. They can even view their debit card account balances--all courtesy of the TC3 Mobile portal. The students at…

  7. Selective and self-guided micro-ablation of tissue with plasmonic nanobubbles

    PubMed Central

    Lukianova-Hleb, Ekaterina Y.; Koneva, Irina I.; Oginsky, Alexander O.; La Francesca, Saverio; Lapotko, Dmitri O.

    2010-01-01

    Background The accuracy, selectivity and safety of surgical and laser methods for tissue elimination are often limited at microscale. Materials and methods We developed a novel agent, the plasmonic nanobubble (PNB), for optically guided selective elimination of the target tissue with micrometer precision. PNBs were tested in vitro in the two different models of superficial tumors and vascular plaques. Results PNBs were selectively generated around gold nanoparticles (delivered to the target tissues) with short laser pulses. Monolayers of cancerous cells and atherosclerotic plaque tissue were eliminated with PNBs with micrometer accuracy and without thermal and mechanical damage to collateral normal tissues. The effect of the PNB was dynamically controlled through the fluence of laser pulses (532 nm, duration 0.5 and 10 ns) and was guided through the optical scattering by PNB. Conclusions plasmonic nanobubbles were shown to provide precise, tunable, selective and guided ablation of tissue at a microcscopic level and could be employed as a new generation of surgical tools. PMID:21176913

  8. Selective and self-guided micro-ablation of tissue with plasmonic nanobubbles.

    PubMed

    Lukianova-Hleb, Ekaterina Y; Koneva, Irina I; Oginsky, Alexander O; La Francesca, Saverio; Lapotko, Dmitri O

    2011-03-01

    The accuracy, selectivity, and safety of surgical and laser methods for tissue elimination are often limited at microscale. We developed a novel agent, the plasmonic nanobubble (PNB), for optically guided selective elimination of the target tissue with micrometer precision. PNBs were tested in vitro in the two different models of superficial tumors and vascular plaques. PNBs were selectively generated around gold nanoparticles (delivered to the target tissues) with short laser pulses. Monolayers of cancerous cells and atherosclerotic plaque tissue were eliminated with PNBs with micrometer accuracy and without thermal and mechanical damage to collateral normal tissues. The effect of the PNB was dynamically controlled through the fluence of laser pulses (532 nm, duration 0.5 and 10 ns) and was guided through the optical scattering by PNB. Plasmonic nanobubbles were shown to provide precise, tunable, selective, and guided ablation of tissue at a microscopic level and could be employed as a new generation of surgical tools. Copyright © 2011 Elsevier Inc. All rights reserved.

  9. Study protocol for a randomised controlled trial of ultrasound-guided pulsed radiofrequency of the genicular nerves in the treatment of patients with osteoarthritis knee pain

    PubMed Central

    Valentí, Pedro; Hernández, Beatriz; Mir, Bartolome; Aguilar, Jose Luis

    2017-01-01

    Introduction The goals for the management of patients with osteoarthritis (OA) of the knee are to control pain and to minimise disability. Because the number of patients will increase as the population ages, alternative approaches to alleviate their joint pain other than conventional treatments are necessary. The purpose of this article is to present a refined protocol to determine if there is long-term improvement in pain and function after ultrasound-guided pulsed radiofrequency treatment of the genicular nerves (GNs) in patients with chronic painful knee OA. Methods and analysis This study is a randomised, double-blind, placebo-controlled, parallel design trial. One hundred and forty-two outpatients with OA of the knee will be recruited from Mallorca, Spain. Participants will be randomly allocated into two groups: ultrasound-guided sham GN pulsed radiofrequency without active treatment and ultrasound-guided real GN pulsed radiofrequency. The primary outcome measures will be the observed changes from baseline pain intensity based on visual analogue scale (VAS). The possible changes in the secondary efficacy variables from the baseline as assessed by the Goldberg Anxiety and Depression Scale, pain medication use, Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC subscales) and VAS pain intensity are also to be included in the study. These variables will be assessed at baseline, 1 month, 3 months, 6 months and 1 year after treatment. Ethics and dissemination The protocol was approved by the Research Ethic Committee of the Balearic Islands (IB 3223/16 PI). The results will be disseminated in peer-reviewed journals and at scientific conferences. Trial registration Trial registration numberNCT02915120; Pre-results PMID:29102985

  10. Nonlinear guiding of picosecond CO2 laser pulses in atmosphere(Conference Presentation)

    NASA Astrophysics Data System (ADS)

    Tochitsky, Sergei

    2017-05-01

    During the last 20 years much attention has been given to the study of propagation of short intense laser pulses for which the peak power exceeds the critical power of self-focusing, Pcr. For a laser power P < Pcr, a dynamic equilibrium between the Kerr self-focusing, diffraction and defocusing caused by laser-ionized plasma result in the production of a high intensity laser filament in air within which a variety of nonlinear optical phenomena are observed. However, research in the 0.8-1 μm range so far has shown a fundamental limitation of guided energy to a few mJ transported within an 100 μm single channel. A long-wavelength, 0 10 μm CO2 laser is a promising candidate for nonlinear guiding because expected high Pcr values according to the modeling should allow for the increase of energy (and therefore power) in a self-guided beam from mJ (GW) to few Joules (TW). During the last decade a significant progress has been achieved in amplification of picosecond pulses to terawatt and recently to <10 TW power level at UCLA and ATF BNL. Such powerful 10 μm lasers open possibility for nonlinear propagation studies in an atmospheric window with high transmission. As a natural first step in a our program on picosecond CO2 laser filamentation, we have made first measurements of Kerr coefficients of air and air constituents around 10 μm. We also undertook direct measurements of n2 of air by analyzing nonlinear self-focusing in air using a 3 ps, 600 GW pulses of the BNL CO2 laser.

  11. Precision guided antiaircraft munition

    DOEpatents

    Hirschfeld, Tomas B.

    1987-01-01

    A small diameter, 20 mm to 50 mm, guided projectile is used in antiaircraft defense. A pulsing laser designator illuminates the target aircraft. Energy reflected from the aircraft is received by the guided projectile. The guided projectile is fired from a standard weapon but the spining caused by the riflings are removed before active tracking and guidance occurs. The received energy is focused by immersion optics onto a bridge cell. AC coupling and gating removes background and allows steering signals to move extended vanes by means of piezoelectric actuators in the rear of the guided projectile.

  12. 1030-nm diode-laser-based light source delivering pulses with nanojoule energies and picosecond duration adjustable by mode locking or pulse gating operation

    NASA Astrophysics Data System (ADS)

    Klehr, A.; Liero, A.; Wenzel, H.; Bugge, F.; Brox, O.; Fricke, J.; Ressel, P.; Knigge, A.; Heinrich, W.; Tränkle, G.

    2017-02-01

    A new compact 1030 nm picosecond light source which can be switched between pulse gating and mode locking operation is presented. It consists of a multi-section distributed Bragg reflector (DBR) laser, an ultrafast multisection optical gate and a flared power amplifier (PA), mounted together with high frequency electronics and optical elements on a 5×4 cm micro bench. The master oscillator (MO) is a 10 mm long ridge wave-guide (RW) laser consisting of 200 μm long saturable absorber, 1500 μm long gain, 8000 μm long cavity, 200 μm long DBR and 100 μm long monitor sections. The 2 mm long optical gate consisting of several RW sections is monolithically integrated with the 4 mm long gain-guided tapered amplifier on a single chip. The light source can be switched between pulse gating and passive mode locking operation. For pulse gating all sections of the MO (except of the DBR and monitor sections) are forward biased and driven by a constant current. By injecting electrical pulses into one section of the optical gate the CW beam emitted by the MO is converted into a train of optical pulses with adjustable widths between 250 ps and 1000 ps. Peak powers of 20 W and spectral linewidths in the MHz range are achieved. Shorter pulses with widths between 4 ps and 15 ps and peak powers up to 50 W but larger spectral widths of about 300 pm are generated by mode locking where the saturable absorber section of the MO is reversed biased. The repetition rate of 4.2 GHz of the pulse train emitted by the MO can be reduced to values between 1 kHz and 100 MHz by utilizing the optical gate as pulse picker. The pulse-to-pulse distance can be controlled by an external trigger source.

  13. Laser guiding of Tesla coil high voltage discharges.

    PubMed

    Henriksson, Markus; Daigle, Jean-Francois; Théberge, Francis; Châteauneuf, Marc; Dubois, Jacques

    2012-06-04

    We have investigated the guiding and triggering of discharges from a Tesla coil type 280 kHz AC high voltage source using filaments created by a femtosecond Terawatt laser pulse. Without the laser the discharges were maximum 30 cm long. With the laser straight, guided discharges up to 110 cm length were detected. The discharge length was limited by the voltage amplitude of the Tesla coil.

  14. New laser surface treatments: cleaning, derusting, deoiling, depainting, deoxidizing, and degreasing

    NASA Astrophysics Data System (ADS)

    Daurelio, Giuseppe; Chita, Giuseppe; Cinquepalmi, Massimo

    1997-08-01

    Many materials as substrates and surface products have been tested. Typically ferrous (Carbon Steels and Stainless Steels) and non ferrous (Al and Cu metals and its alloys) ones have been employed. Some epoxy, polyurethane, polyester and acrylic paints in different thickness and color have been tested. Many types of the surface rust and oxide on different bulk material have been undertaken to test. Similarly some different types of oils and greases, usually used in industry against the oxidation, have been studied. Anyway many types of dirt, grit, calcareous one and so on, present on industrial components, have been laser cleaned without using solvents, acid baths and other ones. Different types of laser sources have been employed: an axial fast flow, 1.5 KW CO2 c.w. and pulsed laser source, emitting a 10.6 micrometers beam; a portable CO2 laser, c.w. (1 to 25 W) and pulsed (1 to 100 Hz and 400 ms max pulse duration) source, emitting a 10.6 micrometers beam with a multi-articulated seven mirrors guiding device and focussing head; a portable Nd-YAG laser, Q-switched and normal-mode source. 1st harmonic 1.06 micrometers (6 ns pulse duration), 2nd harmonic 532 nm (120 microsecond(s) duration pulse- 1J max per-pulse) wavelengths, multi-articulated seven mirrors beam guiding device, 20 Hz repetition rate. This lets shots with 600 mJ max energy per pulse and 100 MW peak power per-pulse with a very low beam divergence, 0.5 mrad at full angle; a transverse fast flow 2.5 kW CO2 laser.

  15. Noninvasive Label-Free Detection of Micrometastases in the Lymphatics with Ultrasound-Guided Photoacoustic Imaging

    DTIC Science & Technology

    2015-10-01

    imaging can be used to guide dissection. We have also successfully integrated a programmable ultrasound machine (Verasonics Vantage ) and tunable pulsed...Mobile HE) with the programmable ultrasound machine (Verasonics Vantage ). We have synchronized the signals to enable interleaved acquisition of US

  16. Manipulation of optical-pulse-imprinted memory in a Λ system

    NASA Astrophysics Data System (ADS)

    Gutiérrez-Cuevas, Rodrigo; Eberly, Joseph H.

    2015-09-01

    We examine coherent memory manipulation in a Λ -type medium, using the second-order solution presented by Groves, Clader, and Eberly [J. Phys. B: At. Mol. Opt. Phys. 46, 224005 (2013), 10.1088/0953-4075/46/22/224005] as a guide. The analytical solution obtained using the Darboux transformation and a nonlinear superposition principle describes complicated soliton-pulse dynamics which, by an appropriate choice of parameters, can be simplified to a well-defined sequence of pulses interacting with the medium. In this report, this solution is reviewed and put to test by means of a series of numerical simulations, encompassing all the parameter space and adding the effects of homogeneous broadening due to spontaneous emission. We find that even though the decohered results deviate from the analytical prediction they do follow a similar trend that could be used as a guide for future experiments.

  17. Multistage Coupling of Laser-Wakefield Accelerators with Curved Plasma Channels.

    PubMed

    Luo, J; Chen, M; Wu, W Y; Weng, S M; Sheng, Z M; Schroeder, C B; Jaroszynski, D A; Esarey, E; Leemans, W P; Mori, W B; Zhang, J

    2018-04-13

    Multistage coupling of laser-wakefield accelerators is essential to overcome laser energy depletion for high-energy applications such as TeV-level electron-positron colliders. Current staging schemes feed subsequent laser pulses into stages using plasma mirrors while controlling electron beam focusing with plasma lenses. Here a more compact and efficient scheme is proposed to realize the simultaneous coupling of the electron beam and the laser pulse into a second stage. A partly curved channel, integrating a straight acceleration stage with a curved transition segment, is used to guide a fresh laser pulse into a subsequent straight channel, while the electrons continue straight. This scheme benefits from a shorter coupling distance and continuous guiding of the electrons in plasma while suppressing transverse beam dispersion. Particle-in-cell simulations demonstrate that the electron beam from a previous stage can be efficiently injected into a subsequent stage for further acceleration while maintaining high capture efficiency, stability, and beam quality.

  18. Multistage Coupling of Laser-Wakefield Accelerators with Curved Plasma Channels

    NASA Astrophysics Data System (ADS)

    Luo, J.; Chen, M.; Wu, W. Y.; Weng, S. M.; Sheng, Z. M.; Schroeder, C. B.; Jaroszynski, D. A.; Esarey, E.; Leemans, W. P.; Mori, W. B.; Zhang, J.

    2018-04-01

    Multistage coupling of laser-wakefield accelerators is essential to overcome laser energy depletion for high-energy applications such as TeV-level electron-positron colliders. Current staging schemes feed subsequent laser pulses into stages using plasma mirrors while controlling electron beam focusing with plasma lenses. Here a more compact and efficient scheme is proposed to realize the simultaneous coupling of the electron beam and the laser pulse into a second stage. A partly curved channel, integrating a straight acceleration stage with a curved transition segment, is used to guide a fresh laser pulse into a subsequent straight channel, while the electrons continue straight. This scheme benefits from a shorter coupling distance and continuous guiding of the electrons in plasma while suppressing transverse beam dispersion. Particle-in-cell simulations demonstrate that the electron beam from a previous stage can be efficiently injected into a subsequent stage for further acceleration while maintaining high capture efficiency, stability, and beam quality.

  19. Note: Characterization of the plasma parameters of a capillary discharge-produced plasma channel waveguide to guide an intense laser pulse

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Higashiguchi, Takeshi; Yugami, Noboru; CREST, Japan Science and Technology Agency, 4-1-8 Honcho, Kanagawa, Saitama 332-0012

    2010-04-15

    We demonstrated the production of an optical waveguide in a capillary discharge-produced plasma using a cylindrical capillary. Plasma parameters of its waveguide were characterized by use of both a Nomarski laser interferometer and a hydrogen plasma line spectrum. A space-averaged maximum temperature of 3.3 eV with electron densities of the order of 10{sup 17} cm{sup -3} was observed at a discharge time of 150 ns and a maximum discharge current of 400 A. An ultrashort, intense laser pulse was guided by use of this plasma channel.

  20. Wave Mode Discrimination of Coded Ultrasonic Guided Waves Using Two-Dimensional Compressed Pulse Analysis.

    PubMed

    Malo, Sergio; Fateri, Sina; Livadas, Makis; Mares, Cristinel; Gan, Tat-Hean

    2017-07-01

    Ultrasonic guided waves testing is a technique successfully used in many industrial scenarios worldwide. For many complex applications, the dispersive nature and multimode behavior of the technique still poses a challenge for correct defect detection capabilities. In order to improve the performance of the guided waves, a 2-D compressed pulse analysis is presented in this paper. This novel technique combines the use of pulse compression and dispersion compensation in order to improve the signal-to-noise ratio (SNR) and temporal-spatial resolution of the signals. The ability of the technique to discriminate different wave modes is also highlighted. In addition, an iterative algorithm is developed to identify the wave modes of interest using adaptive peak detection to enable automatic wave mode discrimination. The employed algorithm is developed in order to pave the way for further in situ applications. The performance of Barker-coded and chirp waveforms is studied in a multimodal scenario where longitudinal and flexural wave packets are superposed. The technique is tested in both synthetic and experimental conditions. The enhancements in SNR and temporal resolution are quantified as well as their ability to accurately calculate the propagation distance for different wave modes.

  1. Department of Defense Agency Financial Report. Fiscal Year 2007

    DTIC Science & Technology

    2007-11-15

    fair market value . The discount rate for the present value calculation is either the lessor’s implicit interest rate or the Government’s...630.0 The Department reports Problem Disbursements as an absolute value , which is the sum of the debit and credit transactions without regard to the...2007 2006 (amounts in millions) Depreciation / Amortization Method Service Life Acquisition Value (Accumulated

  2. 31 CFR 370.1 - What special terms do I need to know to understand this part?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    .... 3101). Investor account is our record of your TreasuryDirect holdings, including a list of your total... ELECTRONIC TRANSACTIONS AND FUNDS TRANSFERS RELATING TO UNITED STATES SECURITIES General Information § 370.1... payment of money to a deposit account. Debit entry means an ACH entry for the collection of money from a...

  3. 12 CFR Appendix A to Part 235 - Official Board Commentary on Regulation II

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    .... Similarly, the term “debit card” includes a device with a chip or other embedded mechanism, such as a mobile... mobile phone) that stores several different payment codes or devices (“virtual cards”) that access... transactions, a cash withdrawal from an ATM is not a payment because there is no exchange of money for goods or...

  4. 12 CFR Appendix A to Part 235 - Official Board Commentary on Regulation II

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    .... Similarly, the term “debit card” includes a device with a chip or other embedded mechanism, such as a mobile... mobile phone) that stores several different payment codes or devices (“virtual cards”) that access... transactions, a cash withdrawal from an ATM is not a payment because there is no exchange of money for goods or...

  5. 12 CFR Appendix A to Part 235 - Official Board Commentary on Regulation II

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    .... Similarly, the term “debit card” includes a device with a chip or other embedded mechanism, such as a mobile... mobile phone) that stores several different payment codes or devices (“virtual cards”) that access... transactions, a cash withdrawal from an ATM is not a payment because there is no exchange of money for goods or...

  6. 31 CFR 543.409 - Credit extended and cards issued by U.S. financial institutions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Credit extended and cards issued by U...'IVOIRE SANCTIONS REGULATIONS Interpretations § 543.409 Credit extended and cards issued by U.S. financial..., charge cards, debit cards, or other credit facilities issued by a U.S. financial institution to a person...

  7. 31 CFR 541.408 - Credit extended and cards issued by U.S. financial institutions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Credit extended and cards issued by U... ZIMBABWE SANCTIONS REGULATIONS Interpretations § 541.408 Credit extended and cards issued by U.S. financial..., charge cards, debit cards, or other credit facilities issued by a U.S. financial institution to a person...

  8. 78 FR 75373 - Agency Information Collection Activities: Proposed Collection; Comments Requested; Application To...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-11

    ... to the form are to allow applicants to pay the transfer tax by credit or debit card, and combine... amount of time estimated for an average respondent to respond: It is estimated that 9,662 respondents will take an average of approximately 1.69 hours to complete. (6) An estimate of the total burden (in...

  9. 76 FR 9067 - Self-Regulatory Organizations; Notice of Filing and Immediate Effectiveness of Proposed Rule...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-16

    ... pay a rebate solely for Customer complex orders that add liquidity in order to continue to attract... because this Customer rebate would attract Customer order flow to the Exchange for the benefit of all..., priced at a net debit or credit based on the relative prices of the individual components, for the same...

  10. Today's Program Is Brought to You by the Letters--Debit and Credit and by the Number Income

    ERIC Educational Resources Information Center

    Bush, H. Francis; Walsh, Vonda K.

    2011-01-01

    As each generation comes of age they receive a label. Currently, we are teaching the new millennials. Their learning style and time management preferences may respond better to a constant task and feedback cycle similar to the popular Public Television Series, Sesame Street. This paper examines the effects of requiring students to take an…

  11. Pension Accounting and Reporting with Other Comprehensive Income and Deferred Taxes: A Worksheet Approach

    ERIC Educational Resources Information Center

    Jackson, Robert E.; Sneathen, L. Dwight, Jr.; Veal, Timothy R.

    2012-01-01

    This instructional tool presents pension accounting using a worksheet approach where debits equal credits for both the employer and for the plan. Transactions associated with the initiation of the plan through the end of the second year of the plan are presented, including their impact on accumulated other comprehensive income and deferred taxes.…

  12. Money Matters: The American Experience with Money.

    ERIC Educational Resources Information Center

    Gittings, Tom; Goldsmith, Ken

    From the earliest times when commodities such as tobacco and beaver pelts were used as money, to the present when credit and debit cards are commonplace, money has played a central role in the U.S. experience. This booklet provides an historical overview of the concept of money as it has evolved in the United States. The booklet is divided into…

  13. CAMPUS Debit Cards Act

    THOMAS, 113th Congress

    Rep. Miller, George [D-CA-11

    2014-05-22

    House - 05/22/2014 Referred to the Committee on Financial Services, and in addition to the Committee on Education and the Workforce, for a period to be subsequently determined by the Speaker, in each case for consideration of such provisions as fall within the jurisdiction of the... (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  14. Modeling the interdependent network based on two-mode networks

    NASA Astrophysics Data System (ADS)

    An, Feng; Gao, Xiangyun; Guan, Jianhe; Huang, Shupei; Liu, Qian

    2017-10-01

    Among heterogeneous networks, there exist obviously and closely interdependent linkages. Unlike existing research primarily focus on the theoretical research of physical interdependent network model. We propose a two-layer interdependent network model based on two-mode networks to explore the interdependent features in the reality. Specifically, we construct a two-layer interdependent loan network and develop several dependent features indices. The model is verified to enable us to capture the loan dependent features of listed companies based on loan behaviors and shared shareholders. Taking Chinese debit and credit market as case study, the main conclusions are: (1) only few listed companies shoulder the main capital transmission (20% listed companies occupy almost 70% dependent degree). (2) The control of these key listed companies will be more effective of avoiding the spreading of financial risks. (3) Identifying the companies with high betweenness centrality and controlling them could be helpful to monitor the financial risk spreading. (4) The capital transmission channel among Chinese financial listed companies and Chinese non-financial listed companies are relatively strong. However, under greater pressure of demand of capital transmission (70% edges failed), the transmission channel, which constructed by debit and credit behavior, will eventually collapse.

  15. On the feasibility of a fiber-based inertial fusion laser driver

    NASA Astrophysics Data System (ADS)

    Labaune, C.; Hulin, D.; Galvanauskas, A.; Mourou, G. A.

    2008-08-01

    One critical issue for the realization of Inertial Fusion Energy (IFE) power plants is the driver efficiency. High driver efficiency will greatly relax the driver energy requested to produce a fusion gain, resulting in more compact and less costly facilities. Among lasers, systems based on guided wave such as diode pumped Yb:glass fiber-amplifiers with a demonstrated overall efficiency close to 70% as opposed to few percents for systems based on free propagation, offer some intriguing opportunities. Guided optics provides the enormous advantage to directly benefit from the telecommunication industry where components are made cheap, rugged, well tested, environmentally stable, with lifetimes measured in tens of years and compatible with massive manufacturing. In this paper, we are studying the possibility to design a laser driver solely based on guided wave optics. We call this concept FAN for Fiber Amplification Network. It represents a profound departure from already proposed laser drivers all based on free propagation optics. The system will use a large number of identical fibers to combines long (ns) and short (ps) pulses that are needed for the fast ignition scheme. Technical details are discussed relative to fiber type, pump, phasing, pulse shaping and timing as well as fiber distribution around the chamber. The proposed fiber driver provides maximum and independent control on the wavefront, pulse duration, pulse shape, timing, making possible reaching the highest gain. The massive manufacturing will be amenable to a cheaper facility with an easy upkeep.

  16. Randomized and controlled prospective trials of Ultrasound-guided spinal nerve posterior ramus pulsed radiofrequency treatment for lower back post-herpetic neuralgia.

    PubMed

    Pi, Z B; Lin, H; He, G D; Cai, Z; Xu, X Z

    2015-01-01

    To evaluate the efficacy of ultrasound-guided spinal nerve posterior ramus pulsed radiofrequency treatment for lower back post-herpetic neuralgia. 128 cases of lower back or anterior abdominal wall acute post-herpetic neuralgia patients were selected. They were randomly divided into two groups. Group A: oral treatment only with gabapentin + celecoxib + amitriptyline. Group B: while taking these drugs, patients were treated with radiofrequency (RF) pulses using a portable ultrasound device using the paravertebral puncture technique. In both groups, sudden outbreaks of pain were treated with immediate release 10mg morphine tablets. Visual analogue scale (VAS) was used for pain score, Pittsburgh Sleep Quality Index scale (PSQI) was used to evaluate sleep quality and morphine consumption were recorded at different time points, before and after treatment. Treatment efficiency was calculated while the occurrence of complications was documented. At each time point after treatment, VAS scores were lower, but scores in the RF group was significantly lower than those of the oral-only group. In terms of sleep quality scores and morphine consumption between the two groups, the RF group was significantly lower than the oral-only group. During the procedure no error occurred with needle penetrating the abdominal cavity, chest, offal or blood vessels. Ultrasound-guided spinal nerve posterior ramus pulsed radiofrequency treatment of lower back or anterior abdominal wall post-herpetic neuralgia proved effective by reducing morphine use in patients and led to fewer adverse reactions.

  17. A simulation model for predicting the temperature during the application of MR-guided focused ultrasound for stroke treatment using pulsed ultrasound

    NASA Astrophysics Data System (ADS)

    Hadjisavvas, V.; Damianou, C.

    2011-09-01

    In this paper a simulation model for predicting the temperature during the application of MR-guided focused ultrasound for stroke treatment using pulsed ultrasound is presented. A single element spherically focused transducer of 5 cm diameter, focusing at 10 cm and operating at either 0.5 MHz or 1 MHz was considered. The power field was estimated using the KZK model. The temperature was estimated using the bioheat equation. The goal was to extract the acoustic parameters (power, pulse duration, duty factor and pulse repetition frequency) that maintain a temperature increase of less than 1 °C during the application of a pulse ultrasound protocol. It was found that the temperature change increases linearly with duty factor. The higher the power, the lower the duty factor needed to keep the temperature change to the safe limit of 1 °C. The higher the frequency the lower the duty factor needed to keep the temperature change to the safe limit of 1 °C. Finally, the deeper the target, the higher the duty factor needed to keep the temperature change to the safe limit of 1 °C. The simulation model was tested in brain tissue during the application of pulse ultrasound and the measured temperature was in close agreement with the simulated temperature. This simulation model is considered to be very useful tool for providing acoustic parameters (frequency, power, duty factor, pulse repetition frequency) during the application of pulsed ultrasound at various depths in tissue so that a safe temperature is maintained during the treatment. This model could be tested soon during stroke clinical trials.

  18. The best marker for guiding the clinical management of patients with raised intracranial pressure-the RAP index or the mean pulse amplitude?

    PubMed

    Hall, Allan; O'Kane, Roddy

    2016-10-01

    Raised intracranial pressure is a common problem in a variety of neurosurgical conditions including traumatic brain injury, hydrocephalus and intracranial haemorrhage. The clinical management of these patients is guided by a variety of haemodynamic, biochemical and clinical factors. However to date there is no single parameter that is used to guide clinical management of patients with raised intracranial pressure (ICP). However, the role of ICP indices, specifically the mean pulse amplitude (AMP) and RAP index [correlation coefficient (R) between AMP amplitude (A) and mean ICP pressure (P); index of compensatory reserve], as an indicator of true ICP has been investigated. Whilst the RAP index has been used both as a descriptor of neurological deterioration in TBI patients and as a way of characterising the compensatory reserve in hydrocephalus, more recent studies have highlighted the limitation of the RAP index due to the influence that baseline effect errors have on the mean ICP, which is used in the calculation of the RAP index. These studies have suggested that the ICP mean pulse amplitude may be a more accurate marker of true intracranial pressure due to the fact that it is uninfluenced by the mean ICP and, therefore, the AMP may be a more reliable marker than the RAP index for guiding the clinical management of patients with raised ICP. Although further investigation needs to be undertaken in order to fully assess the role of ICP indices in guiding the clinical management of patients with raised ICP, the studies undertaken to date provide an insight into the potential role of ICP indices to treat raised ICP proactively rather than reactively and therefore help prevent or minimise secondary brain injury.

  19. Satellite Mapping of Rain-Induced Nitric Oxide Emissions from Soils

    NASA Technical Reports Server (NTRS)

    Jaegle, L.; Martin, R. V.; Chance, K.; Steinberger, L.; Kurosu, T. P.; Jacob, D. J.; Modi, A. I.; Yoboue, V.; Sigha-Nkamdjou, L.; Galy-Lacaux, C.

    2004-01-01

    We use space-based observations of NO2 columns from the Global Ozone Monitoring Experiment (GOME) to map the spatial and seasonal variations of NOx emissions over Africa during 2000. The GOME observations show not only enhanced tropospheric NO2 columns from biomass burning during the dry season but also comparable enhancements from soil emissions during the rainy season over the Sahel. These soil emissions occur in strong pulses lasting 1-3 weeks following the onset of rain, and affect 3 million sq km of semiarid sub-Saharan savanna. Surface observations of NO2 from the International Global Atmospheric Chemistry (IGAC)/Deposition of Biochemically Important Trace Species (DEBITS)/Africa (IDAF) network over West Africa provide further evidence for a strong role for microbial soil sources. By combining inverse modeling of GOME NO2 columns with space-based observations of fires, we estimate that soils contribute 3.3+/-1.8 TgN/year, similar to the biomass burning source (3.8+/-2.1 TgN/year), and thus account for 40% of surface NO(x) emissions over Africa. Extrapolating to all the tropics, we estimate a 7.3 TgN/year biogenic soil source, which is a factor of 2 larger compared to model-based inventories but agrees with observation-based inventories. These large soil NO(x) emissions are likely to significantly contribute to the ozone enhancement originating from tropical Africa.

  20. Coronary CT Angiography Incorporating Doppler-Guided Prospective ECG Gating in Patients with High Heart Rate: Comparison with Results of Traditional Prospective ECG Gating

    PubMed Central

    Li, Min; Yu, Bing-bing; Wu, Jian-hua; Xu, Lin; Sun, Gang

    2013-01-01

    Purpose As Doppler ultrasound has been proven to be an effective tool to predict and compress the optimal pulsing windows, we evaluated the effective dose and diagnostic accuracy of coronary CT angiography (CTA) incorporating Doppler-guided prospective electrocardiograph (ECG) gating, which presets pulsing windows according to Doppler analysis, in patients with a heart rate >65 bpm. Materials and Methods 119 patients with a heart rate >65 bpm who were scheduled for invasive coronary angiography were prospectively studied, and patients were randomly divided into traditional prospective (n = 61) and Doppler-guided prospective (n = 58) ECG gating groups. The exposure window of traditional prospective ECG gating was set at 30%–80% of the cardiac cycle. For the Doppler group, the length of diastasis was analyzed by Doppler. For lengths greater than 90 ms, the pulsing window was preset during diastole (during 60%–80%); otherwise, the optimal pulsing intervals were moved from diastole to systole (during 30%–50%). Results The mean heart rates of the traditional ECG and the Doppler-guided group during CT scanning were 75.0±7.7 bpm (range, 66–96 bpm) and 76.5±5.4 bpm (range: 66–105 bpm), respectively. The results indicated that whereas the image quality showed no significant difference between the traditional and Doppler groups (P = 0.42), the radiation dose of the Doppler group was significantly lower than that of the traditional group (5.2±3.4mSv vs. 9.3±4.5mSv, P<0.001). The sensitivities of CTA applying traditional and Doppler-guided prospective ECG gating to diagnose stenosis on a segment level were 95.5% and 94.3%, respectively; specificities 98.0% and 97.1%, respectively; positive predictive values 90.7% and 88.2%, respectively; negative predictive values 99.0% and 98.7%, respectively. There was no statistical difference in concordance between the traditional and Doppler groups (P = 0.22). Conclusion Doppler-guided prospective ECG gating represents an improved method in patients with a high heart rate to reduce effective radiation doses, while maintaining high diagnostic accuracy. PMID:23696793

  1. 31 CFR 356.17 - How and when do I pay for securities awarded in an auction?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 31 Money and Finance: Treasury 2 2014-07-01 2014-07-01 false How and when do I pay for securities... telephone, you must pay for any securities awarded to you by debit entry to a deposit account. (2) Bidding... account. In your payment amount you must include the par amount and any announced accrued interest and/or...

  2. 31 CFR 356.17 - How and when do I pay for securities awarded in an auction?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 31 Money and Finance:Treasury 2 2013-07-01 2013-07-01 false How and when do I pay for securities... telephone, you must pay for any securities awarded to you by debit entry to a deposit account. (2) Bidding... account. In your payment amount you must include the par amount and any announced accrued interest and/or...

  3. 31 CFR 356.17 - How and when do I pay for securities awarded in an auction?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 31 Money and Finance:Treasury 2 2011-07-01 2011-07-01 false How and when do I pay for securities... telephone, you must pay for any securities awarded to you by debit entry to a deposit account. (2) Bidding... account. In your payment amount you must include the par amount and any announced accrued interest and/or...

  4. 31 CFR 356.17 - How and when do I pay for securities awarded in an auction?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 31 Money and Finance:Treasury 2 2012-07-01 2012-07-01 false How and when do I pay for securities... telephone, you must pay for any securities awarded to you by debit entry to a deposit account. (2) Bidding... account. In your payment amount you must include the par amount and any announced accrued interest and/or...

  5. 78 FR 17725 - Self-Regulatory Organizations; NASDAQ OMX PHLX LLC; Notice of Filing and Immediate Effectiveness...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-22

    ... debit or credit based on the relative prices of the individual components, for the same account, for the... market system and, in general, to protect investors and the public interest. \\6\\ 15 U.S.C. 78f. \\7\\ 15 U.S.C. 78f(b)(5). Specifically, the Exchange believes that investors and other market participants...

  6. 12 CFR 220.122 - “Deep in the money put and call options” as extensions of credit.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... fall in excess of 30 percent, but the risk of such a decline is extremely slight. (j) Like any other... effect counted twice, § 220.3(d)(5) requires that in computing the customer's adjusted debit balance... right would be exercised. But even if the price fell, unlike the situation with a normal option, the...

  7. 40 CFR 86.1818-12 - Greenhouse gas emission standards for light-duty vehicles, light-duty trucks, and medium-duty...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...-equivalent debits for a test group using an alternative N2O or CH4 standard; GWP = 25 if calculating CH4...) CONTROL OF EMISSIONS FROM NEW AND IN-USE HIGHWAY VEHICLES AND ENGINES General Compliance Provisions for Control of Air Pollution From New and In-Use Light-Duty Vehicles, Light-Duty Trucks, and Complete Otto...

  8. 40 CFR 86.1861-04 - How do the Tier 2 and interim non-Tier 2 NOX averaging, banking and trading programs work?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 2 NOX averaging, banking and trading programs work? 86.1861-04 Section 86.1861-04 Protection of... work? (a) General provisions for Tier 2 credits and debits. (1) A manufacturer whose Tier 2 fleet... to a full useful life of 100,000 miles, provided that the credits are prorated by a multiplicative...

  9. 180 mJ, long-pulse-duration, master-oscillator power amplifier with linewidth less than 25.6 kHz for laser guide stars.

    PubMed

    Wang, Chunhua; Zhang, Xiang; Ye, Zhibin; Liu, Chong; Chen, Jun

    2013-07-01

    A high-energy single-frequency hundred-microsecond long-pulse solid-state laser is demonstrated, which features an electro-optically modulated seed laser and two-stage double-passed pulse-pumped solid-state laser rod amplifier. Laser output with energy of 180 mJ, repetition rate of 50 Hz, and pulse width of 150 μs is achieved. The laser linewidth is measured to be less than 25.52 kHz by a fiber delay self-heterodyne method. In addition, a closed-loop controlling system is adopted to lock the center wavelength. No relaxation oscillation spikes appear in the pulse temporal profile, which is beneficial for further amplification.

  10. Controlling Plasma Channels through Ultrashort Laser Pulse Filamentation

    NASA Astrophysics Data System (ADS)

    Ionin, Andrey; Seleznev, Leonid; Sunchugasheva, Elena

    2013-09-01

    A review of studies fulfilled at the Lebedev Institute in collaboration with the Moscow State University and Institute of Atmospheric Optics in Tomsk on influence of various characteristics of ultrashort laser pulse on plasma channels formed under its filamentation is presented. Filamentation of high-power laser pulses with wavefront controlled by a deformable mirror, with cross-sections spatially formed by various diaphragms and with different wavelengths was experimentally and numerically studied. An application of plasma channels formed due to filamentation of ultrashort laser pulse including a train of such pulses for triggering and guiding long electric discharges is discussed. The research was supported by RFBR Grants 11-02-12061-ofi-m and 11-02-01100, and EOARD Grant 097007 through ISTC Project 4073 P

  11. A patient-mount navigated intervention system for spinal diseases and its clinical trial on percutaneous pulsed radiofrequency stimulation of dorsal root ganglion.

    PubMed

    Yang, Chi-Lin; Yang, Been-Der; Lin, Mu-Lien; Wang, Yao-Hung; Wang, Jaw-Lin

    2010-10-01

    Development of a patient-mount navigated intervention (PaMNI) system for spinal diseases. An in vivo clinical human trial was conducted to validate this system. To verify the feasibility of the PaMNI system with the clinical trial on percutaneous pulsed radiofrequency stimulation of dorsal root ganglion (PRF-DRG). Two major image guiding techniques, i.e., computed tomography (CT)-guided and fluoro-guided, were used for spinal intervention. The CT-guided technique provides high spatial resolution, and is claimed to be more accurate than the fluoro-guided technique. Nevertheless, the CT-guided intervention usually reaches higher radiograph exposure than the fluoro-guided counterpart. Some navigated intervention systems were developed to reduce the radiation of CT-guided intervention. Nevertheless, these systems were not popularly used due to the longer operation time, a new protocol for surgeons, and the availability of such a system. The PaMNI system includes 3 components, i.e., a patient-mount miniature tracking unit, an auto-registered reference frame unit, and a user-friendly image processing unit. The PRF-DRG treatment was conducted to find the clinical feasibility of this system. The in vivo clinical trial showed that the accuracy, visual analog scale evaluation after surgery, and radiograph exposure of the PaMNI-guided technique are comparable to the one of conventional fluoro-guided technique, while the operation time is increased by 5 minutes. Combining the virtues of fluoroscopy and CT-guided techniques, our navigation system is operated like a virtual fluoroscopy with augmented CT images. This system elevates the performance of CT-guided intervention and reduces surgeons' radiation exposure risk to a minimum, while keeping low radiation dose to patients like its fluoro-guided counterpart. The clinical trial of PRF-DRG treatment showed the clinical feasibility and efficacy of this system.

  12. Oxygen saturation profile in healthy preterm infants.

    PubMed

    Harigopal, S; Satish, H P; Taktak, A F G; Southern, K W; Shaw, N J

    2011-09-01

    To establish a reference range for oxygen saturation (SpO(2)) in well preterm infants to guide home oxygen therapy using a pulse oximeter and Pulse Oximetry Data Analysis Software (PODS). SpO(2) and heart-rate profiles of healthy preterm infants receiving mechanical ventilation for less than 6 h and supplemental oxygen for less than 48 h were monitored using a pulse oximeter. The stored data were downloaded from the monitor to a personal computer as individual files. Each infant's files of SpO(2) were subsequently displayed in graphic form, and a reference range was constructed using dedicated software, PODS. 43 infants were studied. The median value of all infants mean SpO(2) values was 95% (range 92-99%). The median duration of saturations less than 85% and between 85% and 90 % were 1% and 2% respectively. Using the study group median, 5th and 95th percentiles, a cumulative frequency curve of time against SpO(2) value was constructed (representing the reference range of SpO(2) profiles in healthy preterm infants). The SpO(2) reference range can be used as an easy and practical guide to compare SpO(2) profiles of infants on home oxygen therapy and guide their oxygen therapy.

  13. Measurements of self-guiding of ultrashort laser pulses over long distances

    NASA Astrophysics Data System (ADS)

    Poder, K.; Cole, J. M.; Wood, J. C.; Lopes, N. C.; Alatabi, S.; Foster, P. S.; Kamperidis, C.; Kononenko, O.; Palmer, C. A.; Rusby, D.; Sahai, A.; Sarri, G.; Symes, D. R.; Warwick, J. R.; Mangles, S. P. D.; Najmudin, Z.

    2018-01-01

    We report on the evaluation of the performance of self-guiding over extended distances with f/20 and f/40 focussing geometries. Guiding over 39 {mm} or more than 100 Rayleigh ranges was observed with the f/20 optic at {n}e=1.5× {10}18 {{cm}}-3. Analysis of guiding performance found that the extent of the exiting laser spatial mode closely followed the matched spot size predicted by 3D nonlinear theory. Self-guiding with an f/40 optic was also characterised, with guided modes observed for a plasma length of 90 {mm} and a plasma density of {n}e=9.5× {10}17 {{cm}}-3. This corresponds to self-guided propagation over 53 Rayleigh ranges and is similar to distances obtained with discharge plasma channel guiding.

  14. Guided acoustic wave inspection system

    DOEpatents

    Chinn, Diane J.

    2004-10-05

    A system for inspecting a conduit for undesirable characteristics. A transducer system induces guided acoustic waves onto said conduit. The transducer system detects the undesirable characteristics of the conduit by receiving guided acoustic waves that contain information about the undesirable characteristics. The conduit has at least two sides and the transducer system utilizes flexural modes of propagation to provide inspection using access from only the one side of the conduit. Cracking is detected with pulse-echo testing using one transducer to both send and receive the guided acoustic waves. Thinning is detected in through-transmission testing where one transducer sends and another transducer receives the guided acoustic waves.

  15. Nanopore formation in neuroblastoma cells following ultrashort electric pulse exposure

    NASA Astrophysics Data System (ADS)

    Roth, Caleb C.; Payne, Jason A.; Wilmink, Gerald J.; Ibey, Bennett L.

    2011-03-01

    Ultrashort or nanosecond electrical pulses (USEP) cause repairable damage to the plasma membranes of cells through formation of nanopores. These nanopores are able to pass small ions such as sodium, calcium, and potassium, but remain impermeable to larger molecules like trypan blue and propidium iodide. What remains uncertain is whether generation of nanopores by ultrashort electrical pulses can inhibit action potentials in excitable cells. In this paper, we explored the sensitivity of excitable cells to USEP using Calcium Green AM 1 ester fluorescence to measure calcium uptake indicative of nanopore formation in the plasma membrane. We determined the threshold for nanopore formation in neuroblastoma cells for three pulse parameters (amplitude, pulse width, and pulse number). Measurement of such thresholds will guide future studies to determine if USEP can inhibit action potentials without causing irreversible membrane damage.

  16. Multistage Coupling of Laser-Wakefield Accelerators with Curved Plasma Channel

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Luo, J.; Chen, M.; Wu, W. Y.

    Multistage coupling of laser-wakefield accelerators is essential to overcome laser energy depletion for high-energy applications such as TeV level electron-positron colliders. Current staging schemes feed subsequent laser pulses into stages using plasma mirrors, while controlling electron beam focusing with plasma lenses. Here a more compact and efficient scheme is proposed to realize simultaneous coupling of the electron beam and the laser pulse into a second stage. Furthermore, a curved channel with transition segment is used to guide a fresh laser pulse into a subsequent straight channel, while allowing the electrons to propagate in a straight channel. This scheme then benefitsmore » from a shorter coupling distance and continuous guiding of the electrons in plasma, while suppressing transverse beam dispersion. Within moderate laser parameters, particle-in-cell simulations demonstrate that the electron beam from a previous stage can be efficiently injected into a subsequent stage for further acceleration, while maintaining high capture efficiency, stability, and beam quality.« less

  17. Multistage Coupling of Laser-Wakefield Accelerators with Curved Plasma Channel

    DOE PAGES

    Luo, J.; Chen, M.; Wu, W. Y.; ...

    2018-04-10

    Multistage coupling of laser-wakefield accelerators is essential to overcome laser energy depletion for high-energy applications such as TeV level electron-positron colliders. Current staging schemes feed subsequent laser pulses into stages using plasma mirrors, while controlling electron beam focusing with plasma lenses. Here a more compact and efficient scheme is proposed to realize simultaneous coupling of the electron beam and the laser pulse into a second stage. Furthermore, a curved channel with transition segment is used to guide a fresh laser pulse into a subsequent straight channel, while allowing the electrons to propagate in a straight channel. This scheme then benefitsmore » from a shorter coupling distance and continuous guiding of the electrons in plasma, while suppressing transverse beam dispersion. Within moderate laser parameters, particle-in-cell simulations demonstrate that the electron beam from a previous stage can be efficiently injected into a subsequent stage for further acceleration, while maintaining high capture efficiency, stability, and beam quality.« less

  18. Tesla coil discharges guided by femtosecond laser filaments in air

    NASA Astrophysics Data System (ADS)

    Brelet, Yohann; Houard, Aurélien; Arantchouk, Leonid; Forestier, Benjamin; Liu, Yi; Prade, Bernard; Carbonnel, Jérôme; André, Yves-Bernard; Mysyrowicz, André

    2012-04-01

    A Tesla coil generator was designed to produce high voltage pulses oscillating at 100 kHz synchronisable with a nanosecond temporal jitter. Using this compact high voltage generator, we demonstrate reproducible meter long discharges in air at a repetition rate of 1 Hz. Triggering and guiding of the discharges are performed in air by femtosecond laser filaments.

  19. 1-J white-light continuum from 100-TW laser pulses

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Petit, Yannick; Henin, Stefano; Bejot, Pierre

    2011-01-15

    We experimentally measured the supercontinuum generation using 3-J, 30-fs laser pulses and measured white-light generation at the level of 1 J. Such high energy is allowed by a strong contribution to the continuum by the photon bath, as compared to the self-guided filaments. This contribution due to the recently observed congestion of the filament number density in the beam profile at very high intensity also results in a wider broadening for positively chirped pulses rather than for negatively chirped ones, similar to broadening in hollow-core fibers.

  20. 40 CFR 86.1861-04 - How do the Tier 2 and interim non-Tier 2 NOX averaging, banking and trading programs work?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... amount of emissions. Nothing in this part or any other provision of law should be construed to limit EPA... negative number, the manufacturer must generate negative NOX credits (debits). (c) Early banking. (1)(i... emission standards specified in § 86.1811-04. (iii) This process is referred to as “early banking” and the...

  1. Software Engineering Institute: Year in Review 2008

    DTIC Science & Technology

    2008-01-01

    security information they need. Now, new podcasts are uploaded every two weeks to the CERT website and iTunes . The series has become increasingly...reused throughout an organization— customer lookup, account lookup, and credit card validation are some examples. 2008 YEAR IN REVIEW...were charged in August 2008 with the theft of more than 40 million credit and debit card numbers from T.J. Maxx, Marshall’s, Barnes & Noble

  2. 75 FR 12773 - Notice of Proposed Information Collection: Comment Request Ginnie Mae Mortgage-Backed Securities...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-17

    ... 210 0.016 3.4 Agreement. 11709 III-2 Master Agreement 210 1 210 0.033 6.9 for Servicer's Principal and....016 2.3 Certification for Construction Securities. IX-1 Financial 210 1 210 1 210.0 Statements and Audit Reports. Mortgage Bankers 350 4 1400 0.5 700.0 Financial Reporting Form. 11709-A I-6 ACH Debit 210...

  3. SE Capstone Project: Building Systems Engineering Education and Workforce Capacity

    DTIC Science & Technology

    2012-04-01

    This project developed a system to improve fuel efficiency by means of regenerative braking . The team designed a simple system that allows "bolt-on...air traffic control, social networking, credit/debit cards, and anti-lock brakes are only a few functions enabled by complex systems of systems . We...Building Systems Engineering Education and Workforce Capacity SE Capstone Project APRIL 2012 Report Documentation Page Form ApprovedOMB No. 0704

  4. A High-Fidelity Simulation of a Generic Commercial Aircraft Engine and Controller

    NASA Technical Reports Server (NTRS)

    May, Ryan D.; Csank, Jeffrey; Lavelle, Thomas M.; Litt, Jonathan S.; Guo, Ten-Huei

    2010-01-01

    A new high-fidelity simulation of a generic 40,000 lb thrust class commercial turbofan engine with a representative controller, known as CMAPSS40k, has been developed. Based on dynamic flight test data of a highly instrumented engine and previous engine simulations developed at NASA Glenn Research Center, this non-proprietary simulation was created especially for use in the development of new engine control strategies. C-MAPSS40k is a highly detailed, component-level engine model written in MATLAB/Simulink (The MathWorks, Inc.). Because the model is built in Simulink, users have the ability to use any of the MATLAB tools for analysis and control system design. The engine components are modeled in C-code, which is then compiled to allow faster-than-real-time execution. The engine controller is based on common industry architecture and techniques to produce realistic closed-loop transient responses while ensuring that no safety or operability limits are violated. A significant feature not found in other non-proprietary models is the inclusion of transient stall margin debits. These debits provide an accurate accounting of the compressor surge margin, which is critical in the design of an engine controller. This paper discusses the development, characteristics, and capabilities of the C-MAPSS40k simulation

  5. Time-resolved in vivo luminescence dosimetry for online error detection in pulsed dose-rate brachytherapy.

    PubMed

    Andersen, Claus E; Nielsen, Søren Kynde; Lindegaard, Jacob Christian; Tanderup, Kari

    2009-11-01

    The purpose of this study is to present and evaluate a dose-verification protocol for pulsed dose-rate (PDR) brachytherapy based on in vivo time-resolved (1 s time resolution) fiber-coupled luminescence dosimetry. Five cervix cancer patients undergoing PDR brachytherapy (Varian GammaMed Plus with 192Ir) were monitored. The treatments comprised from 10 to 50 pulses (1 pulse/h) delivered by intracavitary/interstitial applicators (tandem-ring systems and/or needles). For each patient, one or two dosimetry probes were placed directly in or close to the tumor region using stainless steel or titanium needles. Each dosimeter probe consisted of a small aluminum oxide crystal attached to an optical fiber cable (1 mm outer diameter) that could guide radioluminescence (RL) and optically stimulated luminescence (OSL) from the crystal to special readout instrumentation. Positioning uncertainty and hypothetical dose-delivery errors (interchanged guide tubes or applicator movements from +/-5 to +/-15 mm) were simulated in software in order to assess the ability of the system to detect errors. For three of the patients, the authors found no significant differences (P>0.01) for comparisons between in vivo measurements and calculated reference values at the level of dose per dwell position, dose per applicator, or total dose per pulse. The standard deviations of the dose per pulse were less than 3%, indicating a stable dose delivery and a highly stable geometry of applicators and dosimeter probes during the treatments. For the two other patients, the authors noted significant deviations for three individual pulses and for one dosimeter probe. These deviations could have been due to applicator movement during the treatment and one incorrectly positioned dosimeter probe, respectively. Computer simulations showed that the likelihood of detecting a pair of interchanged guide tubes increased by a factor of 10 or more for the considered patients when going from integrating to time-resolved dose verification. The likelihood of detecting a +/-15 mm displacement error increased by a factor of 1.5 or more. In vivo fiber-coupled RL/OSL dosimetry based on detectors placed in standard brachytherapy needles was demonstrated. The time-resolved dose-rate measurements were found to provide a good way to visualize the progression and stability of PDR brachytherapy dose delivery, and time-resolved dose-rate measurements provided an increased sensitivity for detection of dose-delivery errors compared with time-integrated dosimetry.

  6. Pulse compression using a tapered microstructure optical fiber.

    PubMed

    Hu, Jonathan; Marks, Brian S; Menyuk, Curtis R; Kim, Jinchae; Carruthers, Thomas F; Wright, Barbara M; Taunay, Thierry F; Friebele, E J

    2006-05-01

    We calculate the pulse compression in a tapered microstructure optical fiber with four layers of holes. We show that the primary limitation on pulse compression is the loss due to mode leakage. As a fiber's diameter decreases due to the tapering, so does the air-hole diameter, and at a sufficiently small diameter the guided mode loss becomes unacceptably high. For the four-layer geometry we considered, a compression factor of 10 can be achieved by a pulse with an initial FWHM duration of 3 ps in a tapered fiber that is 28 m long. We find that there is little difference in the pulse compression between a linear taper profile and a Gaussian taper profile. More layers of air-holes allows the pitch to decrease considerably before losses become unacceptable, but only a moderate increase in the degree of pulse compression is obtained.

  7. Sonothrombolysis of Intra-Catheter Aged Venous Thrombi Using Microbubble Enhancement and Guided Three Dimensional Ultrasound Pulses

    PubMed Central

    Kutty, Shelby; Xie, Feng; Gao, Shunji; Drvol, Lucas K; Lof, John; Fletcher, Scott E; Radio, Stanley J; Danford, David A; Hammel, James M; Porter, Thomas R

    2010-01-01

    Central venous and arterial catheters are a major source of thrombo-embolic disease in children. We hypothesized that guided high mechanical index (MI) impulses from diagnostic three-dimensional (3D) ultrasound during an intravenous microbubble infusion could dissolve these thrombi. An in vitro system simulating intra-catheter thrombi was created and then treated with guided high MI impulses from 3D ultrasound, utilizing low MI microbubble sensitive imaging pulse sequence schemes to detect the microbubbles (Perflutren Lipid Microsphere, Definity®, Lantheus). Ten aged thrombi over 24 hours old were tested using 3D ultrasound coupled with a continuous diluted microbubble infusion (Group A), and ten with 3D ultrasound alone (Group B). Mean thrombus age was 28.6 hours (range 26.6–30.3). Groups A exhibited a 55 ± 19 % reduction in venous thrombus size, compared to 31±10 % for Group B (p=0.008). Feasibility testing was performed in 4 pigs, establishing a model to further investigate the efficacy. Sonothrombolysis of aged intra-catheter venous thrombi can be achieved with commercially available microbubbles and guided high MI ultrasound from a diagnostic 3D transducer. PMID:20696549

  8. A near-Infrared SETI Experiment: Alignment and Astrometric precision

    NASA Astrophysics Data System (ADS)

    Duenas, Andres; Maire, Jerome; Wright, Shelley; Drake, Frank D.; Marcy, Geoffrey W.; Siemion, Andrew; Stone, Remington P. S.; Tallis, Melisa; Treffers, Richard R.; Werthimer, Dan

    2016-06-01

    Beginning in March 2015, a Near-InfraRed Optical SETI (NIROSETI) instrument aiming to search for fast nanosecond laser pulses, has been commissioned on the Nickel 1m-telescope at Lick Observatory. The NIROSETI instrument makes use of an optical guide camera, SONY ICX694 CCD from PointGrey, to align our selected sources into two 200µm near-infrared Avalanche Photo Diodes (APD) with a field-of-view of 2.5"x2.5" each. These APD detectors operate at very fast bandwidths and are able to detect pulse widths extending down into the nanosecond range. Aligning sources onto these relatively small detectors requires characterizing the guide camera plate scale, static optical distortion solution, and relative orientation with respect to the APD detectors. We determined the guide camera plate scale as 55.9+- 2.7 milli-arcseconds/pixel and magnitude limit of 18.15mag (+1.07/-0.58) in V-band. We will present the full distortion solution of the guide camera, orientation, and our alignment method between the camera and the two APDs, and will discuss target selection within the NIROSETI observational campaign, including coordination with Breakthrough Listen.

  9. Spatiotemporal optical pulse transformation by a resonant diffraction grating

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Golovastikov, N. V.; Bykov, D. A., E-mail: bykovd@gmail.com; Doskolovich, L. L., E-mail: leonid@smr.ru

    The diffraction of a spatiotemporal optical pulse by a resonant diffraction grating is considered. The pulse diffraction is described in terms of the signal (the spatiotemporal incident pulse envelope) passage through a linear system. An analytic approximation in the form of a rational function of two variables corresponding to the angular and spatial frequencies has been obtained for the transfer function of the system. A hyperbolic partial differential equation describing the general form of the incident pulse envelope transformation upon diffraction by a resonant diffraction grating has been derived from the transfer function. A solution of this equation has beenmore » obtained for the case of normal incidence of a pulse with a central frequency lying near the guided-mode resonance of a diffraction structure. The presented results of numerical simulations of pulse diffraction by a resonant grating show profound changes in the pulse envelope shape that closely correspond to the proposed theoretical description. The results of the paper can be applied in creating new devices for optical pulse shape transformation, in optical information processing problems, and analog optical computations.« less

  10. On-Sky Tests of a High-Power Pulsed Laser for Sodium Laser Guide Star Adaptive Optics

    NASA Astrophysics Data System (ADS)

    Otarola, Angel; Hickson, Paul; Gagné, Ronald; Bo, Yong; Zuo, Junwei; Xie, Shiyong; Feng, Lu; Rochester, Simon; Budker, Dmitry; Shen, Shixia; Xue, Suijian; Min, Li; Wei, Kai; Boyer, Corinne; Ellerbroek, Brent; Hu, Jingyao; Peng, Qinjun; Xu, Zuyan

    2016-03-01

    We present results of on-sky tests performed in the summer of 2013 to characterize the performance of a prototype high-power pulsed laser for adaptive optics. The laser operates at a pulse repetition rate (PRR) of 600-800Hz, with a 6% duty cycle. Its coupling efficiency was found to be, in the best test case (using 18W of transmitted power), 231±14 photons s-1 sr-1 atom-1 W-1 m2 when circular polarization was employed and 167±17 photons s-1 sr-1 atom-1 W-1 m2 with linear polarization. No improvement was seen when D2b repumping was used, but this is likely due to the relatively large laser guide star (LGS) diameter, typically 10 arcsec or more, which resulted in low irradiance levels. Strong relaxation oscillations were present in the laser output, which have the effect of reducing the coupling efficiency. To better understand the results, a physical modeling was performed using the measured pulse profiles and parameters specific to these tests. The model results, for a 10 arcsec angular size LGS spot, agree well with the observations. When extrapolating the physical model for a sub-arcsecond angular size LGS (typical of what is needed for a successful astronomical guide star), the model predicts that this laser would have a coupling efficiency of 130 photons s-1 sr-1 atom-1 W-1 m2, using circular polarization and D2b repumping, for a LGS diameter of 0.6 arcsec Full Width at Half Maximum (FWHM), and free of relaxation oscillations in the 589 nm laser light.

  11. Nd:YAG Pulsed Laser based flaw imaging techniques for noncontact NDE of an aluminum plate

    NASA Astrophysics Data System (ADS)

    Park, Woong-Ki; Lee, Changgil; Park, Seunghee

    2012-04-01

    Recently, the longitudinal, shear and surface waves have been very widely used as a kind of ultrasonic wave exploration methods to identify internal defects of metallic structures. The ultrasonic wave-based non-destructive testing (NDT) is one of main non-destructive inspection techniques for a health assessment about nuclear power plant, aircraft, ships, and/or automobile manufacturing. In this study, a noncontact pulsed laser-based flaw imaging NDT technique is implemented to detect the damage of a plate-like structure and to identify the location of the damage. To achieve this goal, the Nd:YAG pulsed laser equipment is used to generate a guided wave and scans a specific area to find damage location. The Nd: YAG pulsed laser is used to generate Lamb wave and piezoelectric sensors are installed to measure structural responses. Ann aluminum plate is investigated to verify the effectiveness and the robustness of the proposed NDT approach. A notch is a target to detect, which is inflicted on the surface of an aluminum plate. The damagesensitive features are extracted by comparing the time of flight of the guided wave obtained from an acoustic emission (AE) sensor and make use of the flaw imaging techniques of the aluminum plate.

  12. Application of MR-guided focused pulsed ultrasound for destroying clots in vitro using thrombolytic drugs

    NASA Astrophysics Data System (ADS)

    Hadjisavvas, V.; Ioannides, K.; Damianou, C.

    2011-09-01

    In this paper an MR-guided focused pulsed ultrasound system for the treatment of stroke using thrombolytic drugs in a model in vitro is presented. A single element spherically focused transducer of 5 cm diameter; focusing at 10 cm and operating at 0.5 MHz or 1 MHz was used. The transducer was mounted in an MR compatible robot. The artery was modelled using a silicone tube. Tissue was modelled using polyaclylimide gel. Coagulated blood was used to model thrombus. A thermocouple was placed in the thrombus in order to measure the thrombus temperature. The effect of power, beam, and frequency was investigated. The goal was to maintain a temperature increase of less than 1 °C during the application of pulse ultrasound (called safe temperature). With the application of ultrasound alone there was no notable destruction of the thrombus. With the combination of ultrasound and thrombolytic drugs destruction occurred after 60 mins of pulse exposure (PRF = 1 s, duty factor = 10%, and with thrombus placed at 1 cm deep in the tissue). This simple in vitro model was proven very successful for evaluating MRgFUS as a modality for treating stroke. In the future we plan to apply this treatment protocol in live animals and humans.

  13. Post-filament self-trapping of ultrashort laser pulses.

    PubMed

    Mitrofanov, A V; Voronin, A A; Sidorov-Biryukov, D A; Andriukaitis, G; Flöry, T; Pugžlys, A; Fedotov, A B; Mikhailova, J M; Panchenko, V Ya; Baltuška, A; Zheltikov, A M

    2014-08-15

    Laser filamentation is understood to be self-channeling of intense ultrashort laser pulses achieved when the self-focusing because of the Kerr nonlinearity is balanced by ionization-induced defocusing. Here, we show that, right behind the ionized region of a laser filament, ultrashort laser pulses can couple into a much longer light channel, where a stable self-guiding spatial mode is sustained by the saturable self-focusing nonlinearity. In the limiting regime of negligibly low ionization, this post-filamentation beam dynamics converges to a large-scale beam self-trapping scenario known since the pioneering work on saturable self-focusing nonlinearities.

  14. Post-Attack Economic Stabilization Issues for Federal, State, and Local Governments

    DTIC Science & Technology

    1985-02-01

    workers being transfered from large urban areas to production facilities in areas of lower risk . In another case, rent control staff should be quickly...food supermarkets , which do not universally accept bank cards. 3 0 A requirement will still exist for a large number of credit cards. While there is some...separate system is required for rationing. For example, the increasingly popular automatic teller machine ( ATM ) debit card routinely accesses both a

  15. Communication: XFAIMS—eXternal Field Ab Initio Multiple Spawning for electron-nuclear dynamics triggered by short laser pulses

    DOE PAGES

    Mignolet, Benoit; Curchod, Basile F. E.; Martinez, Todd J.

    2016-11-17

    Attoscience is an emerging field where attosecond pulses or few cycle IR pulses are used to pump and probe the correlated electron-nuclear motion of molecules. We present the trajectory-guided eXternal Field Ab Initio Multiple Spawning (XFAIMS) method that models such experiments “on-the-fly,” from laser pulse excitation to fragmentation or nonadiabatic relaxation to the ground electronic state. For the photoexcitation of the LiH molecule, we show that XFAIMS gives results in close agreement with numerically exact quantum dynamics simulations, both for atto- and femtosecond laser pulses. As a result, we then show the ability of XFAIMS to model the dynamics inmore » polyatomic molecules by studying the effect of nuclear motion on the photoexcitation of a sulfine (H 2CSO).« less

  16. Circularly polarized attosecond pulse generation and applications to ultrafast magnetism

    NASA Astrophysics Data System (ADS)

    Bandrauk, André D.; Guo, Jing; Yuan, Kai-Jun

    2017-12-01

    Attosecond science is a growing new field of research and potential applications which relies on the development of attosecond light sources. Achievements in the generation and application of attosecond pulses enable to investigate electron dynamics in the nonlinear nonperturbative regime of laser-matter interactions on the electron’s natural time scale, the attosecond. In this review, we describe the generation of circularly polarized attosecond pulses and their applications to induce attosecond magnetic fields, new tools for ultrafast magnetism. Simulations are performed on aligned one-electron molecular ions by using nonperturbative nonlinear solutions of the time-dependent Schrödinger equation. We discuss how bichromatic circularly polarized laser pulses with co-rotating or counter-rotating components induce electron-parent ion recollisions, thus producing circularly polarized high-order harmonic generation, the source of circularly polarized attosecond pulses. Ultrafast quantum electron currents created by the generated attosecond pulses give rise to attosecond magnetic field pulses. The results provide a guiding principle for producing circularly polarized attosecond pulses and ultrafast magnetic fields in complex molecular systems for future research in ultrafast magneto-optics.

  17. Metal wires for terahertz wave guiding.

    PubMed

    Wang, Kanglin; Mittleman, Daniel M

    2004-11-18

    Sources and systems for far-infrared or terahertz (1 THz = 10(12) Hz) radiation have received extensive attention in recent years, with applications in sensing, imaging and spectroscopy. Terahertz radiation bridges the gap between the microwave and optical regimes, and offers significant scientific and technological potential in many fields. However, waveguiding in this intermediate spectral region still remains a challenge. Neither conventional metal waveguides for microwave radiation, nor dielectric fibres for visible and near-infrared radiation can be used to guide terahertz waves over a long distance, owing to the high loss from the finite conductivity of metals or the high absorption coefficient of dielectric materials in this spectral range. Furthermore, the extensive use of broadband pulses in the terahertz regime imposes an additional constraint of low dispersion, which is necessary for compatibility with spectroscopic applications. Here we show how a simple waveguide, namely a bare metal wire, can be used to transport terahertz pulses with virtually no dispersion, low attenuation, and with remarkable structural simplicity. As an example of this new waveguiding structure, we demonstrate an endoscope for terahertz pulses.

  18. Caracterisation des revetements par projection thermique a haute vitesse obtenus a partir de differentes poudres de wc-10co-4cr pour des applications en aeronautique =

    NASA Astrophysics Data System (ADS)

    Quintero Malpica, Alfonso

    Les revetements par projection thermique HVOF (High Velocity Oxy-Fuel) sont communement utilises dans l'industrie aeronautique, notamment au sein du partenaire industriel du projet (Tecnickrome Aeronautique Inc), comme des remplacants pour les revetements produits par l'electrodeposition du chrome dur due aux problemes environnementaux. Ce projet avait pour but de trouver une poudre alternative a celle qui est actuellement utilisee pour la production des revetements de type WC-10Co-4Cr obtenus avec la technologie de projection thermique a haute vitesse HVOF et en utilisant le systeme de projection HVOF-JET KOTERTM III. Dans un premier temps, cinq poudres incluant celle de reference, ayant des distributions granulometriques differentes, ont ete projetees dans le but d'identifier quelles poudres pouvaient etre utilisees avec le systeme de projection HVOF-JET KOTERTM III en gardant des parametres similaires (debit d'hydrogene, debit d'oxygene, debit de poudre et distance de projection) que pour la poudre de reference. Les revetements obtenus a partir des poudres etudiees ont ete evalues selon les criteres d'acceptation des revetements sollicites par les principaux manufacturiers des trains d'atterrissage. Les tests ont porte sur l'epaisseur, l'adhesion, la microstructure, la microdurete, les contraintes residuelles et la rugosite. A partir des resultats obtenus, seulement deux poudres ont rencontre toutes les proprietes demandees par les specifications aeronautiques. L'influence de la variation de la distance de projection sur la qualite des revetements a ete etudiee. Cinq distances (100, 125, 150, 175 et 200 mm) ont ete choisies pour faire la projection des deux poudres selectionnees. Les revetements obtenus ont montre de proprietes des revetements similaires (epaisseur, adhesion, microstructure, microdurete, contraintes residuelles et rugosite). Il a ete trouve que la distance de projection est un parametre indirect du systeme de projection HVOF-JET KOTERTM III et qu'autant la vitesse que la temperature des particules semblent mieux determiner les proprietes du revetement, en particulier, les niveaux de contraintes residuelles finales dans les revetements. Lorsque les revetements sont produits a de courtes distances de projection, les particules arrivent avec plus grande vitesse et temperature ce qui resulte dans de plus grandes temperatures du substrat et plus grande energie d'impact, resultant dans de plus grandes contraintes residuelles de compression dans les revetements.

  19. Net Energetics Analysis

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Underhill, Gary K.; Carlson, Ronald A.; Clendinning, William A.

    1976-01-01

    Econimic analysis, next to technical analysis, has traditionally constituted the major decision-making tool of the capitalist economic system. As lon as capitalism survives, this will remain to be the case. However, during the current period of increasing scarcity and cost of energy -- a period accompanied by higher than normal inflation rates -- a proposed project may appear attractive and economic when, in fact, its demands on energy resources are extraordinarily high. Such a conclusion could well be the case when the major energy expenditure in construction or operation is directed toward a fuel, the price of which is heldmore » unusually low by legal regulation. Net energetics analysis, as applied to energy generation facilities, is a method for determining the total amount of energy, IE, required to construct, operate, and maintain the energy generation facility compared to the total energy, TE, generated (or converted) throughout the facility's lifetime. Fuel consumed by the facility as direct input to the conversion or utiliztion process is not considered a debit while energy generated is not considered a credit in the calculation of the construction, operation, and maintenance energy account, IE. Energy required to run equipment auxiliary to the conversion process is, on the other hand, considered a debit to IE. The latter considerations apply to the production, processing, and transport of fuel but not to the energy content of the fuel itself.« less

  20. Wavepacket dynamics of a Rydberg atom monitored by a pair of time-delayed laser pulses

    NASA Astrophysics Data System (ADS)

    Xin, PeiPei; Cheng, Hong; Zhang, ShanShan; Wang, HanMu; Liu, HongPing

    2018-02-01

    We have investigated the Rydberg state population of an argon atom by an intense laser pulse and its wavepacket dynamics monitored by another successive laser pulse in the tunneling regime. A wavepacket comprising a superposition of close high-lying Rydberg states is irradiated by a multicycle laser pulse, where the sub-wave components in the wavepacket have fixed relative phases. A time-delayed second laser pulse is employed to apply on the excited Rydberg atom. If the time is properly chosen, one of the sub-wave components will be guided towards the ionization area while the rest remains intact. By means of this pump-probe technique, we could control and monitor the Rydberg wavepacket dynamics and reveal some interesting phenomenon such as the survival rate of individual Rydberg states related to the classical orbital period of electron.

  1. Self-compression of spatially limited laser pulses in a system of coupled light-guides

    NASA Astrophysics Data System (ADS)

    Balakin, A. A.; Litvak, A. G.; Mironov, V. A.; Skobelev, S. A.

    2018-04-01

    The self-action features of wave packets propagating in a 2D system of equidistantly arranged fibers are studied analytically and numerically on the basis of the discrete nonlinear Schrödinger equation. Self-consistent equations for the characteristic scales of a Gaussian wave packet are derived on the basis of the variational approach, which are proved numerically for powers P < 10 P_cr , slightly exceeding the critical one for self-focusing. At higher powers, the wave beams become filamented, and their amplitude is limited due to the nonlinear breaking of the interaction between neighboring light-guides. This makes it impossible to collect a powerful wave beam in a single light-guide. Variational analysis shows the possibility of the adiabatic self-compression of soliton-like laser pulses in the process of 3D self-focusing on the central light-guide. However, further increase of the field amplitude during self-compression leads to the development of longitudinal modulation instability and the formation of a set of light bullets in the central fiber. In the regime of hollow wave beams, filamentation instability becomes predominant. As a result, it becomes possible to form a set of light bullets in optical fibers located on the ring.

  2. High-frequency guided ultrasonic waves for hidden defect detection in multi-layered aircraft structures.

    PubMed

    Masserey, Bernard; Raemy, Christian; Fromme, Paul

    2014-09-01

    Aerospace structures often contain multi-layered metallic components where hidden defects such as fatigue cracks and localized disbonds can develop, necessitating non-destructive testing. Employing standard wedge transducers, high frequency guided ultrasonic waves that penetrate through the complete thickness were generated in a model structure consisting of two adhesively bonded aluminium plates. Interference occurs between the wave modes during propagation along the structure, resulting in a frequency dependent variation of the energy through the thickness with distance. The wave propagation along the specimen was measured experimentally using a laser interferometer. Good agreement with theoretical predictions and two-dimensional finite element simulations was found. Significant propagation distance with a strong, non-dispersive main wave pulse was achieved. The interaction of the high frequency guided ultrasonic waves with small notches in the aluminium layer facing the sealant and on the bottom surface of the multilayer structure was investigated. Standard pulse-echo measurements were conducted to verify the detection sensitivity and the influence of the stand-off distance predicted from the finite element simulations. The results demonstrated the potential of high frequency guided waves for hidden defect detection at critical and difficult to access locations in aerospace structures from a stand-off distance. Copyright © 2014 The Authors. Published by Elsevier B.V. All rights reserved.

  3. Self-action of Bessel wave packets in a system of coupled light guides and formation of light bullets

    NASA Astrophysics Data System (ADS)

    Balakin, A. A.; Mironov, V. A.; Skobelev, S. A.

    2017-01-01

    The self-action of two-dimensional and three-dimensional Bessel wave packets in a system of coupled light guides is considered using the discrete nonlinear Schrödinger equation. The features of the self-action of such wave fields are related to their initial strong spatial inhomogeneity. The numerical simulation shows that for the field amplitude exceeding a critical value, the development of an instability typical of a medium with the cubic nonlinearity is observed. Various regimes are studied: the self-channeling of a wave beam in one light guide at powers not strongly exceeding a critical value, the formation of the "kaleidoscopic" picture of a wave packet during the propagation of higher-power radiation along a stratified medium, the formation of light bullets during competition between self-focusing and modulation instabilities in the case of three-dimensional wave packets, etc. In the problem of laser pulse shortening, the situation is considered when the wave-field stratification in the transverse direction dominates. This process is accompanied by the self-compression of laser pulses in well enough separated light guides. The efficiency of conversion of the initial Bessel field distribution to two flying parallel light bullets is about 50%.

  4. Self-action of Bessel wave packets in a system of coupled light guides and formation of light bullets

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Balakin, A. A., E-mail: balakin.alexey@yandex.ru; Mironov, V. A.; Skobelev, S. A., E-mail: sk.sa1981@gmail.com

    The self-action of two-dimensional and three-dimensional Bessel wave packets in a system of coupled light guides is considered using the discrete nonlinear Schrödinger equation. The features of the self-action of such wave fields are related to their initial strong spatial inhomogeneity. The numerical simulation shows that for the field amplitude exceeding a critical value, the development of an instability typical of a medium with the cubic nonlinearity is observed. Various regimes are studied: the self-channeling of a wave beam in one light guide at powers not strongly exceeding a critical value, the formation of the “kaleidoscopic” picture of a wavemore » packet during the propagation of higher-power radiation along a stratified medium, the formation of light bullets during competition between self-focusing and modulation instabilities in the case of three-dimensional wave packets, etc. In the problem of laser pulse shortening, the situation is considered when the wave-field stratification in the transverse direction dominates. This process is accompanied by the self-compression of laser pulses in well enough separated light guides. The efficiency of conversion of the initial Bessel field distribution to two flying parallel light bullets is about 50%.« less

  5. Large scale Tesla coil guided discharges initiated by femtosecond laser filamentation in air

    NASA Astrophysics Data System (ADS)

    Arantchouk, L.; Point, G.; Brelet, Y.; Prade, B.; Carbonnel, J.; André, Y.-B.; Mysyrowicz, A.; Houard, A.

    2014-07-01

    The guiding of meter scale electric discharges produced in air by a Tesla coil is realized in laboratory using a focused terawatt laser pulse undergoing filamentation. The influence of the focus position, the laser arrival time, or the gap length is studied to determine the best conditions for efficient laser guiding. Discharge parameters such as delay, jitter, and resistance are characterized. An increase of the discharge length by a factor 5 has been achieved with the laser filaments, corresponding to a mean breakdown field of 2 kV/cm for a 1.8 m gap length. Consecutive guided discharges at a repetition rate of 10 Hz are also reported.

  6. Development of a fiber-guided laser ultrasonic system resilient to high temperature and gamma radiation for nuclear power plant pipe monitoring

    NASA Astrophysics Data System (ADS)

    Yang, Jinyeol; Lee, Hyeonseok; Lim, Hyung Jin; Kim, Nakhyeon; Yeo, Hwasoo; Sohn, Hoon

    2013-08-01

    This study develops an embeddable optical fiber-guided laser ultrasonic system for structural health monitoring (SHM) of pipelines exposed to high temperature and gamma radiation inside nuclear power plants (NPPs). Recently, noncontact laser ultrasonics is gaining popularity among the SHM community because of its advantageous characteristics such as (a) scanning capability, (b) immunity against electromagnetic interference (EMI) and (c) applicability to high-temperature surfaces. However, its application to NPP pipelines has been hampered because pipes inside NPPs are often covered by insulators and/or target surfaces are not easily accessible. To overcome this problem, this study designs embeddable optical fibers and fixtures so that laser beams used for ultrasonic inspection can be transmitted between the laser sources and the target pipe. For guided-wave generation, an Nd:Yag pulsed laser coupled with an optical fiber is used. A high-power pulsed laser beam is guided through the optical fiber onto a target structure. Based on the principle of laser interferometry, the corresponding response is measured using a different type of laser beam guided by another optical fiber. All devices are especially designed to sustain high temperature and gamma radiation. The robustness/resilience of the proposed measurement system installed on a stainless steel pipe specimen has been experimentally verified by exposing the specimen to high temperature of up to 350 °C and optical fibers to gamma radiation of up to 125 kGy (20 kGy h-1).

  7. A Guide to Making an Audio Tape.

    ERIC Educational Resources Information Center

    Jobe, Holly; Cannon, Glenn

    This brief introduction to the use of audiotape recorders in educational settings provides basic information on operational procedures and recording techniques for voice, music, dubbing, and pulsing. Audiotape editing and splicing are also explained. (RAO)

  8. Blocking and guiding adult sea lamprey with pulsed direct current from vertical electrodes

    USGS Publications Warehouse

    Johnson, Nicholas S.; Thompson, Henry T.; Holbrook, Christopher M.; Tix, John A.

    2014-01-01

    Controlling the invasion front of aquatic nuisance species is of high importance to resource managers. We tested the hypothesis that adult sea lamprey (Petromyzon marinus), a destructive invasive species in the Laurentian Great Lakes, would exhibit behavioral avoidance to dual-frequency pulsed direct current generated by vertical electrodes and that the electric field would not injure or kill sea lamprey or non-target fish. Laboratory and in-stream experiments demonstrated that the electric field blocked sea lamprey migration and directed sea lamprey into traps. Rainbow trout (Oncorhynchus mykiss) and white sucker (Catostomus commersoni), species that migrate sympatrically with sea lamprey, avoided the electric field and had minimal injuries when subjected to it. Vertical electrodes are advantageous for fish guidance because (1) the electric field produced varies minimally with depth, (2) the electric field is not grounded, reducing power consumption to where portable and remote deployments powered by solar, wind, hydro, or a small generator are feasible, and (3) vertical electrodes can be quickly deployed without significant stream modification allowing rapid responses to new invasions. Similar dual-frequency pulsed direct current fields produced from vertical electrodes may be advantageous for blocking or trapping other invasive fish or for guiding valued fish around dams.

  9. THz-driven zero-slippage IFEL scheme for phase space manipulation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Curry, E.; Fabbri, S.; Musumeci, P.

    In this paper, we describe an inverse free electron laser (IFEL) interaction driven by a near single-cycle THz pulse that is group velocity-matched to an electron bunch inside a waveguide, allowing for a sustained interaction in a magnetic undulator. We discuss the application of this guided-THz IFEL technique for compression of a relativistic electron bunch and synchronization with the external laser pulse used to generate the THz pulse via optical rectification, as well as a laser-driven THz streaking diagnostic with the potential for femtosecond scale temporal resolution. Initial measurements of the THz waveform via an electro-optic sampling based technique confirm the predicted reduction of the group velocity, using a curved parallel plate waveguide, as a function of the varying aperture size of the guide. We also present the design of a proof-of-principle experiment based on the bunch parameters available at the UCLA PEGASUS laboratory. With amore » $$10\\,\\mathrm{MV}\\,{{\\rm{m}}}^{-1}$$ THz peak field, our simulation model predicts compression of a $$6\\,\\mathrm{MeV}$$ $$100\\,\\mathrm{fs}$$ electron beam by nearly an order of magnitude and a significant reduction of its initial timing jitter.« less

  10. THz-driven zero-slippage IFEL scheme for phase space manipulation

    DOE PAGES

    Curry, E.; Fabbri, S.; Musumeci, P.; ...

    2016-11-24

    In this paper, we describe an inverse free electron laser (IFEL) interaction driven by a near single-cycle THz pulse that is group velocity-matched to an electron bunch inside a waveguide, allowing for a sustained interaction in a magnetic undulator. We discuss the application of this guided-THz IFEL technique for compression of a relativistic electron bunch and synchronization with the external laser pulse used to generate the THz pulse via optical rectification, as well as a laser-driven THz streaking diagnostic with the potential for femtosecond scale temporal resolution. Initial measurements of the THz waveform via an electro-optic sampling based technique confirm the predicted reduction of the group velocity, using a curved parallel plate waveguide, as a function of the varying aperture size of the guide. We also present the design of a proof-of-principle experiment based on the bunch parameters available at the UCLA PEGASUS laboratory. With amore » $$10\\,\\mathrm{MV}\\,{{\\rm{m}}}^{-1}$$ THz peak field, our simulation model predicts compression of a $$6\\,\\mathrm{MeV}$$ $$100\\,\\mathrm{fs}$$ electron beam by nearly an order of magnitude and a significant reduction of its initial timing jitter.« less

  11. Polarization-dependent intermodal four-wave mixing in a birefringent multimode photonic crystal fiber.

    PubMed

    Yuan, Jinhui; Kang, Zhe; Li, Feng; Zhou, Guiyao; Sang, Xinzhu; Wu, Qiang; Yan, Binbin; Zhou, Xian; Zhong, Kangping; Wang, Liang; Wang, Kuiru; Yu, Chongxiu; Lu, Chao; Tam, Hwa Yaw; Wai, P K A

    2017-05-01

    In this Letter, polarization-dependent intermodal four-wave mixing (FWM) is demonstrated experimentally in a birefringent multimode photonic crystal fiber (BM-PCF) designed and fabricated in-house. Femtosecond pump pulses at wavelengths ∼800  nm polarized along one of the principal axes of the BM-PCF are coupled into a normal dispersion region away from the zero-dispersion wavelengths of the fundamental guided mode of the BM-PCF. Anti-Stokes and Stokes waves are generated in the 2nd guided mode at visible and near-infrared wavelengths, respectively. For pump pulses at an average input power of 500 mW polarized along the slow axis, the conversion efficiencies ηas and ηs of the anti-Stokes and Stokes waves generated at wavelengths 579.7 and 1290.4 nm are 19% and 14%, respectively. For pump pulses polarized along the fast axis, the corresponding ηas and ηs at 530.4 and 1627 nm are 23% and 18%, respectively. We also observed that fiber bending and intermodal walk-off have a small effect on the polarization-dependent intermodal FWM-based frequency conversion process.

  12. Development of a fluorimeter using laser-induced single-shot fluorescence lifetime spectroscopy

    NASA Astrophysics Data System (ADS)

    Eisum, Niels H.; Lynggaard-Jensen, Anders

    1990-08-01

    The developed laboratory prototype fluorimeter is the first step to a new in-situ instrument, and is based on a pulsed nitrogen laser (pumping a color dye laser and the laserbeam passing through a frequency doubler) with a pulse width less than 1 nsec. With such a short excitation pulse it is possible to measure the exponential decay of the fluorescence from the aromatic compounds and thus determine the fluorescence lifetime-curves, which are typically in the region of 5-40 nsec. The emitted fluorescence is collected simultaneously in 35 channels in the wavelength region 250-600 nm. If the fluorescence falls within the transmission areas of the interference filters in each channel the light will be collected by a plastic light guide (doped PMMA) in the actual channel and transmitted to the channels photo multiplier tube (PMT). (The use of the plastic light guide improves the sensitivity). The signal from the PMT is passed on to a 200 MHz 8-bit flash AID-converter connected to a local memory. From this local memory the digital lifetime curves from each channel are transmitted to a computer for presentation of the 3-dimensional spectrum. This spectrum has been obtained with a single laser shot.

  13. Nonlinear compression of temporal solitons in an optical waveguide via inverse engineering

    NASA Astrophysics Data System (ADS)

    Paul, Koushik; Sarma, Amarendra K.

    2018-03-01

    We propose a novel method based on the so-called shortcut-to-adiabatic passage techniques to achieve fast compression of temporal solitons in a nonlinear waveguide. We demonstrate that soliton compression could be achieved, in principle, at an arbitrarily small distance by inverse-engineering the pulse width and the nonlinearity of the medium. The proposed scheme could possibly be exploited for various short-distance communication protocols and may be even in nonlinear guided wave-optics devices and generation of ultrashort soliton pulses.

  14. High-resolution imaging and target designation through clouds or smoke

    DOEpatents

    Perry, Michael D.

    2003-01-01

    A method and system of combining gated intensifiers and advances in solid-state, short-pulse laser technology, compact systems capable of producing high resolution (i.e., approximately less than 20 centimeters) optical images through a scattering medium such as dense clouds, fog, smoke, etc. may be achieved from air or ground based platforms. Laser target designation through a scattering medium is also enabled by utilizing a short pulse illumination laser and a relatively minor change to the detectors on laser guided munitions.

  15. Serial removal of caries lesions from tooth occlusal surfaces using near-IR image-guided IR laser ablation

    NASA Astrophysics Data System (ADS)

    Chan, Kenneth H.; Tom, Henry; Darling, Cynthia L.; Fried, Daniel

    2015-02-01

    Previous studies have established that caries lesions can be imaged with high contrast without the interference of stains at near-IR wavelengths greater than 1300-nm. It has been demonstrated that computer controlled laser scanning systems utilizing IR lasers operating at high pulse repetition rates can be used for serial imaging and selective removal of caries lesions. In this study, we report our progress towards the development of algorithms for generating rasterized ablation maps from near-IR reflectance images for the removal of natural lesions from tooth occlusal surfaces. An InGaAs camera and a filtered tungsten-halogen lamp producing near-IR light in the range of 1500-1700-nm were used to collect crosspolarization reflectance images of tooth occlusal surfaces. A CO2 laser operating at a wavelength of 9.3- μm with a pulse duration of 10-15-μs was used for image-guided ablation.

  16. Enhanced hole boring with two-color relativistic laser pulses in the fast ignition scheme

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Yu, Changhai; Tian, Ye; Li, Wentao

    A scheme of using two-color laser pulses for hole boring into overdense plasma as well as energy transfer into electron and ion beams has been studied using particle-in-cell simulations. Following an ultra-short ultra-intense hole-boring laser pulse with a short central wavelength in extreme ultra-violet range, the main infrared driving laser pulse can be guided in the hollow channel preformed by the former laser and propagate much deeper into an overdense plasma, as compared to the case using the infrared laser only. In addition to efficiently transferring the main driving laser energy into energetic electrons and ions generation deep inside themore » overdense plasma, the ion beam divergence can be greatly reduced. The results might be beneficial for the fast ignition concept of inertial confinement fusion.« less

  17. Modeling of intense pulsed ion beam heated masked targets for extreme materials characterization

    DOE PAGES

    Barnard, John J.; Schenkel, Thomas

    2017-11-15

    Intense, pulsed ion beams locally heat materials and deliver dense electronic excitations that can induce material modifications and phase transitions. Material properties can potentially be stabilized by rapid quenching. Pulsed ion beams with pulse lengths of order ns have recently become available for materials processing. Here, we optimize mask geometries for local modification of materials by intense ion pulses. The goal is to rapidly excite targets volumetrically to the point where a phase transition or local lattice reconstruction is induced followed by rapid cooling that stabilizes desired material's properties fast enough before the target is altered or damaged by, e.g.,more » hydrodynamic expansion. By using a mask, the longitudinal dimension can be large compared to the transverse dimension, allowing the possibility of rapid transverse cooling. We performed HYDRA simulations that calculate peak temperatures for a series of excitation conditions and cooling rates of silicon targets with micro-structured masks and compare these to a simple analytical model. In conclusion, the model gives scaling laws that can guide the design of targets over a wide range of pulsed ion beam parameters.« less

  18. Nonlinear Dichroism in Back-to-Back Double Ionization of He by an Intense Elliptically Polarized Few-Cycle Extreme Ultraviolet Pulse.

    PubMed

    Ngoko Djiokap, J M; Manakov, N L; Meremianin, A V; Hu, S X; Madsen, L B; Starace, Anthony F

    2014-11-28

    Control of double ionization of He by means of the polarization and carrier-envelope phase (CEP) of an intense, few-cycle extreme ultraviolet (XUV) pulse is demonstrated numerically by solving the six-dimensional two-electron, time-dependent Schrödinger equation for He interacting with an elliptically polarized XUV pulse. Guided by perturbation theory (PT), we predict the existence of a nonlinear dichroic effect (∝I^{3/2}) that is sensitive to the CEP, ellipticity, peak intensity I, and temporal duration of the pulse. This dichroic effect (i.e., the difference of the two-electron angular distributions for opposite helicities of the ionizing XUV pulse) originates from interference of first- and second-order PT amplitudes, allowing one to probe and control S- and D-wave channels of the two-electron continuum. We show that the back-to-back in-plane geometry with unequal energy sharing is an ideal one for observing this dichroic effect that occurs only for an elliptically polarized, few-cycle attosecond pulse.

  19. Initial state-specific photodissociation dynamics of pyrrole via 1 π σ ∗/ S 0 conical intersection initiated with optimally controlled UV-laser pulses

    NASA Astrophysics Data System (ADS)

    Nandipati, K. R.; Kanakati, Arun Kumar; Singh, H.; Lan, Z.; Mahapatra, S.

    2017-09-01

    Optimal initiation of quantum dynamics of N-H photodissociation of pyrrole on the S0-1πσ∗(1A2) coupled electronic states by UV-laser pulses in an effort to guide the subsequent dynamics to dissociation limits is studied theoretically. Specifically, the task of designing optimal laser pulses that act on initial vibrational states of the system for an effective UV-photodissociation is considered by employing optimal control theory. The associated control mechanism(s) for the initial state dependent photodissociation dynamics of pyrrole in the presence of control pulses is examined and discussed in detail. The initial conditions determine implicitly the variation in the dissociation probabilities for the two channels, upon interaction with the field. The optimal pulse corresponds to the objective fixed as maximization of overall reactive flux subject to constraints of reasonable fluence and quantum dynamics. The simple optimal pulses obtained by the use of genetic algorithm based optimization are worth an experimental implementation given the experimental relevance of πσ∗-photochemistry in recent times.

  20. Control of ultrafast pulses in a hydrogen-filled hollow-core photonic-crystal fiber by Raman coherence

    NASA Astrophysics Data System (ADS)

    Belli, F.; Abdolvand, A.; Travers, J. C.; Russell, P. St. J.

    2018-01-01

    We present the results of an experimental and numerical investigation into temporally nonlocal coherent interactions between ultrashort pulses, mediated by Raman coherence, in a gas-filled kagome-style hollow-core photonic-crystal fiber. A pump pulse first sets up the Raman coherence, creating a refractive index spatiotemporal grating in the gas that travels at the group velocity of the pump pulse. Varying the arrival time of a second, probe, pulse allows a high degree of control over its evolution as it propagates along the fiber through the grating. Of particular interest are soliton-driven effects such as self-compression and dispersive wave (DW) emission. In the experiments reported, a DW is emitted at ˜300 nm and exhibits a wiggling effect, with its central frequency oscillating periodically with pump-probe delay. The results demonstrate that a strong Raman coherence, created in a broadband guiding gas-filled kagome photonic-crystal fiber, can be used to control the nonlinear dynamics of ultrashort probe pulses, even in difficult-to-access spectral regions such as the deep and vacuum ultraviolet.

  1. Modeling of intense pulsed ion beam heated masked targets for extreme materials characterization

    NASA Astrophysics Data System (ADS)

    Barnard, John J.; Schenkel, Thomas

    2017-11-01

    Intense, pulsed ion beams locally heat materials and deliver dense electronic excitations that can induce material modifications and phase transitions. Material properties can potentially be stabilized by rapid quenching. Pulsed ion beams with pulse lengths of order ns have recently become available for materials processing. Here, we optimize mask geometries for local modification of materials by intense ion pulses. The goal is to rapidly excite targets volumetrically to the point where a phase transition or local lattice reconstruction is induced followed by rapid cooling that stabilizes desired material's properties fast enough before the target is altered or damaged by, e.g., hydrodynamic expansion. By using a mask, the longitudinal dimension can be large compared to the transverse dimension, allowing the possibility of rapid transverse cooling. We performed HYDRA simulations that calculate peak temperatures for a series of excitation conditions and cooling rates of silicon targets with micro-structured masks and compare these to a simple analytical model. The model gives scaling laws that can guide the design of targets over a wide range of pulsed ion beam parameters.

  2. Image-guided removal of occlusal caries lesions with a λ= 9.3-µm CO2 laser using near-IR transillumination

    PubMed Central

    Chung, Leon C.; Tom, Henry; Chan, Kenneth H.; Simon, Jacob C.; Fried, Daniel; Darling, Cynthia L.

    2015-01-01

    Previous studies have shown that near-IR transillumination is well suited for imaging deep occlusal lesions. The purpose of this study was to determine if near-IR images can be used to guide a CO2 laser for the selective removal of natural occlusal lesions on extracted teeth. Near-IR occlusal transillumination images of extracted human teeth with natural occlusal caries lesions were acquired using an InGaAs camera and near-IR light at wavelengths from 1290 to 1470-nm from a filtered tungsten halogen source. A CO2 laser operating at 9.3-µm with a pulse duration of 10–15-µs and a pulse repetition rate of 100–300-Hz was used for caries removal. Optical Coherence tomography was used to confirm lesion presence and serial scans were used to assess selective removal. Teeth were also sectioned for histological examination using polarized light microscopy. This study suggests that near-infrared transillumination is a promising method for the image guided laser ablation of occlusal caries lesions but the use of serial near-IR transillumination imaging for monitoring lesion removal was limited. PMID:25914498

  3. Image-guided removal of occlusal caries lesions with a λ= 9.3-μm CO2 laser using near-IR transillumination

    NASA Astrophysics Data System (ADS)

    Chung, Leon C.; Tom, Henry; Chan, Kenneth H.; Simon, Jacob C.; Fried, Daniel; Darling, Cynthia L.

    2015-02-01

    Previous studies have shown that near-IR transillumination is well suited for imaging deep occlusal lesions. The purpose of this study was to determine if near-IR images can be used to guide a CO2 laser for the selective removal of natural occlusal lesions on extracted teeth. Near-IR occlusal transillumination images of extracted human teeth with natural occlusal caries lesions were acquired using an InGaAs camera and near-IR light at wavelengths from 1290 to 1470-nm from a filtered tungsten halogen source. A CO2 laser operating at 9.3-μm with a pulse duration of 10-15-μs and a pulse repetition rate of 100-300-Hz was used for caries removal. Optical Coherence tomography was used to confirm lesion presence and serial scans were used to assess selective removal. Teeth were also sectioned for histological examination using polarized light microscopy. This study suggests that near-infrared transillumination is a promising method for the image guided laser ablation of occlusal caries lesions but the use of serial near-IR transillumination imaging for monitoring lesion removal was limited.

  4. Experimental generation of discrete ultraviolet wavelength by cascaded intermodal four-wave mixing in a multimode photonic crystal fiber.

    PubMed

    Yuan, Jinhui; Kang, Zhe; Li, Feng; Zhang, Xianting; Mei, Chao; Zhou, Guiyao; Sang, Xinzhu; Wu, Qiang; Yan, Binbin; Zhou, Xian; Zhong, Kangping; Wang, Kuiru; Yu, Chongxiu; Farrell, Gerald; Lu, Chao; Tam, Hwa Yaw; Wai, P K A

    2017-09-15

    In this Letter, we demonstrate experimentally for the first time, to the best of our knowledge, discrete ultraviolet (UV) wavelength generation by cascaded intermodal FWM when femtosecond pump pulses at 800 nm are launched into the deeply normal dispersion region of the fundamental guided mode of a multimode photonic crystal fiber (MPCF). For pump pulses at average input powers of P av =450, 550, and 650 mW, the first anti-Stokes waves are generated at the visible wavelength of 538.1 nm through intermodal phase matching between the fundamental and second-order guided mode of the MPCF. The first anti-Stokes waves generated then serve as the secondary pump for the next intermodal FWM process. The second anti-Stokes waves in the form of the third-order guided mode are generated at the UV wavelength of 375.8 nm. The maximum output power is above 10 mW for P av =650  mW. We also confirm that the influences of fiber bending and intermodal walk-offs on the cascaded intermodal FWM-based frequency conversion process are negligible.

  5. Surface-Wave Pulse Routing around Sharp Right Angles

    NASA Astrophysics Data System (ADS)

    Gao, Z.; Xu, H.; Gao, F.; Zhang, Y.; Luo, Y.; Zhang, B.

    2018-04-01

    Surface-plasmon polaritons (SPPs), or localized electromagnetic surface waves propagating on a metal-dielectric interface, are deemed promising information carriers for future subwavelength terahertz and optical photonic circuitry. However, surface waves fundamentally suffer from scattering loss when encountering sharp corners in routing and interconnection of photonic signals. Previous approaches enabling scattering-free surface-wave guidance around sharp corners are limited to either volumetric waveguide environments or extremely narrow bandwidth, being unable to guide a surface-wave pulse (SPP wave packet) on an on-chip platform. Here, in a surface-wave band-gap crystal implemented on a single metal surface, we demonstrate in time-domain routing a surface-wave pulse around multiple sharp right angles without perceptible scattering. Our work not only offers a solution to on-chip surface-wave pulse routing along an arbitrary path, but it also provides spatiotemporal information on the interplay between surface-wave pulses and sharp corners, both of which are desirable in developing high-performance large-scale integrated photonic circuits.

  6. Longitudinal Waves Drive the Solar Cycle

    NASA Astrophysics Data System (ADS)

    Wagner, Orvin

    2000-05-01

    In Physics Essays 12: 3-10 I explain the placement of the planets in terms of low velocity waves emitted by the sun. Evidence for the wave pulse generated near the center of the sun is indicated by the initial high latitude sunspots observed on the butterfly diagram. The wave pulse carries charge with it as observed for similar waves in plants (W-waves). For the first half cycle negative charge is carried to the surface of the sun where much of the wave pulse radiates a wave crest into space while the charge slowly redistributes itself. Meanwhile the next wave pulse carrying excess positive charge moves outward. Rotating charge determines the polarity of the sun's magnetic poles so they reverse as the pulse moves outward. The wave pulse, which interacts strongly with force fields, is guided by centripetal force and gravity so that the pulse comes out near the sun's equator. W-waves produce an automatic return wave in the vacuum so that standing waves are produced in the space around the sun providing a template for the formation and stabilization planets. W-waves are hypothesized to provide self organization for both the universe and life. See the

  7. Influence of Ankle Active Dorsiflexion Movement Guided by Inspiration on the Venous Return From the Lower Limbs: A Prospective Study.

    PubMed

    Pi, Hongying; Ku, Hong'an; Zhao, Ting; Wang, Jie; Fu, Yicheng

    2018-04-01

    Active ankle movement is recommended intervention for preventing deep vein thrombosis effectively and easily by promoting venous return from the lower limbs. The active ankle dorsiflexion and plantar flexion movement guided by deep breathing is considered the most effective method, although outstanding problems remain, including low patient compliance and difficult motion essentials. The aims of this study were to compare the influence of different ankle active movements on venous return from the lower limbs and to suggest the optimal movement for preventing deep venous thrombosis in the lower limbs. A self-controlled study on 130 subjects was undertaken. The femoral venous hemodynamics of the left femoral vein and changes in pulse oxygen saturation and heart rate were compared among the three states of quiescent, active ankle 30° dorsiflexion movement, and active ankle 30° dorsiflexion with active plantar 45° flexion movement. The immediate master rates of the two ankle movements were examined before the study. The femoral venous hemodynamics of the left femoral vein were significantly higher in both movement states compared with the quiescent state. Moreover, no significant difference was found among the three states in terms of pulse oxygen saturation and heart rate. The immediate master rate was significantly higher in the active ankle 30° dorsiflexion movement than in the active ankle 30° dorsiflexion and active plantar 45° flexion movement. Therefore, active ankle 30° dorsiflexion movement guided by inspiration was found in this study to increase femoral venous hemodynamics, which heightened the immediate master rate but had no obvious influence on pulse oxygen saturation and heart rate. Active ankle 30° dorsiflexion movement guided by inspiration effectively promotes venous return from the lower limbs and is a better method to prevent deep vein thrombosis of the lower limbs.

  8. A Comparative Study on Dwell Fatigue of Ti-6Al-2Sn-4Zr- xMo ( x = 2 to 6) Alloys on a Microstructure-Normalized Basis

    NASA Astrophysics Data System (ADS)

    Qiu, Jianke; Ma, Yingjie; Lei, Jiafeng; Liu, Yuyin; Huang, Aijun; Rugg, David; Yang, Rui

    2014-12-01

    The dwell effects of Ti624 x ( x = 2 to 6) alloys, including dwell fatigue life debit, fracture mode and strain accumulation, were characterized and compared. With increasing Mo content, the dwell fatigue life debit decreases quickly, and dwell fatigue fracture exhibits a transition from subsurface to surface initiation. Accompanying these changes, the accumulated strain decreases, and the pattern of secondary cracks loses morphological features typical of dwell cracks. These variations in the fatigue behavior of Ti624 x were attributed on the fundamental level to the dual effects of Mo: It decreases the β transus of titanium and, as a slow diffuser, reduces the rate of phase transformation from β to α. A higher Mo content encourages nucleation of multiple variants of α laths and promotes the transition from aligned colonies to basketweave microstructure during cooling after β forging. As a result both the grain size and microtexture intensity of α grains in the two-phase processed and heat treated microstructure are reduced. Smaller grain size of the alloys with higher Mo content produces smaller slip band spacing and reduces accumulated strain during dwell fatigue, thus reducing propensity for crack initiation. Microtexture was shown to be the direct cause of dwell sensitivity, and their relationship was described with the aid of a two-region redistribution model based on a previous two-element redistribution model proposed by Bache.

  9. Study of morphometry to debit drainage basin (DAS) arau Padang city

    NASA Astrophysics Data System (ADS)

    Utama, Lusi; Amrizal, Berd, Isril; Zuherna

    2017-11-01

    High intensity rain that happened in Padang city cause the happening of floods at DAS Arau. Floods that happened in Padang besides caused high rain intensity, require to be by research about morphometry that is cause parameter the happening of floods. Morphometry drainage basin physical network (DAS) quantitatively related to DAS geomorphology that is related to form of DAS, river network, closeness of stream, ramp, usage of farm, high and gradient steepness of river. Form DAS will influence rain concentration to outlet. Make an index to closeness of stream depict closeness of river stream at one particular DAS. Speed of river stream influenced by storey, level steepness of river. Steepness storey, level is comparison of difference height of river downstream and upstream. Ever greater of steepness of river stream, excelsior speed of river stream that way on the contrary. High to lower speed of river stream influence occurrence of floods, more than anything else if when influenced by debit big. Usage of farm in glove its link to process of infiltration where if geology type which is impermeable, be difficult the happening of infiltration, this matter will enlarge value of run off. Research by descriptive qualitative that is about characteristic of DAS. Method the used is method survey with data collecting, in the form of rainfall data of year 2005 until year 2015 and Image of DEM IFSAR with resolution 5 meter, analyzed use Software ARGIS. Result of research got by DAS reside in at condition of floods gristle.

  10. Investigation experimentale de l'ecoulement et des performances thermiques du nanofluide eau-oxyde de cuivre dans un Micro-Canal Chauffe

    NASA Astrophysics Data System (ADS)

    Rimbault, Benjamin

    Cette these de maitrise presentee par articles visait a etudier le comportement hydraulique et thermique d'un ecoulement de nanofluides en micro-canal chauffe. Nous avons etudie premierement de l'eau distillee, ensuite des melanges de particules d'oxyde de cuivre (taille 29nm) avec de l'eau distillee en concentrations particulaires volumiques 4.5%, 1.03%, et 0.24% (CuO-H2O). L'ecoulement force des differents fluides a ete realise au moyen de pompes a engrenages au sein d'un circuit ferme, comprenant un micro-canal a section rectangulaire (e=1.116mm,1=25.229mm) chauffe sur deux faces paralleles via des cartouches electriques, deux echangeurs de chaleurs en serie, ainsi qu'un debitmetre magnetique. A notre connaissance peu d'etudes sur l'ecoulement de nanofluides d'oxyde de cuivre-eau en micro-canal rectangulaire chauffe sont disponibles dans la litterature, cette recherche sert de contribution. Premierement, une validation avec la litterature a ete effectuee pour le cas d'un ecoulement d'eau entre plaques planes paralleles chauffees. Des essais hydrauliques ont ete realises pour une gamme du nombre de Reynolds allant jusqu'a Re=5000 a temperature constante. Par la suite des essais thermiques jusqu'a Re=2500 ont consiste en une elevation de temperature fixe (20.5°C a 30.5°C) a travers la longueur du micro-canal sous un regime stationnaire. Les resultats ont demontre une augmentation de la perte de pression et du coefficient de frottement des nanofluides sur l'eau pour un meme debit. Une telle augmentation de perte de pression etait de +70%, +25%, et +0 a 30% respectivement pour les concentrations 4.50%, 1.03%, et 0.24%. Concernant la transition laminaire a turbulent les comportements semblaient indiquer une valeur critique semblable entre l'eau et les differentes concentrations avec et sans chauffage a un nombre de Reynolds critique Rem 1000. Nous avons observe une legere augmentation du coefficient de convection thermique avec le debit massique pour les faibles concentrations (1.03% et 0.24%), alors que la concentration 4.5% demontre une nette diminution. En general la performance energetique globale definie par la chaleur transferee sur la puissance de pompage, reste inferieure compare a l'eau pour un meme Reynolds et un meme debit massique egalement. L'eau semble etre la meilleure solution en termes de performance energetique globale.

  11. Microcomponents manufacturing for precise devices by copper vapor laser

    NASA Astrophysics Data System (ADS)

    Gorny, Sergey; Nikonchuk, Michail O.; Polyakov, Igor V.

    2001-06-01

    This paper presents investigation results of drilling of metal microcomponents by copper vapor laser. The laser consists of master oscillator - spatial filter - amplifier system, electronics switching with digital control of laser pulse repetition rate and quantity of pulses, x-y stage with computer control system. Mass of metal, removed by one laser pulse, is measured and defined by means of diameter and depth of holes. Interaction of next pulses on drilled material is discussed. The difference between light absorption and metal evaporation processes is considered for drilling and cutting. Efficiency of drilling is estimated by ratio of evaporation heat and used laser energy. Maximum efficiency of steel cutting is calculated with experimental data of drilling. Applications of copper vapor laser for manufacturing is illustrated by such microcomponents as pin guide plate for printers, stents for cardio surgery, encoded disks for security systems and multiple slit masks for spectrophotometers.

  12. Electromagnetically driven radiative shocks and their measurements

    NASA Astrophysics Data System (ADS)

    Kondo, K.; Nakajima, M.; Kawamura, T.; Horioka, K.

    2006-06-01

    Experimental results on a generation of strong shocks in a compact pulse power device are reported. To make a strong and plain shock wave, electrodes are tapered and an acrylic guiding tube is located on the top of the electrodes. It drives a quasi-one-dimensional strong shock in the guiding tube. When the front speed is more than the critical speed Drad, an interesting structure is confirmed at the shock front, which indicate a phenomenon proceeded by the radiative transport.

  13. 20 mJ, 1 ps Yb:YAG Thin-disk Regenerative Amplifier

    PubMed Central

    Alismail, Ayman; Wang, Haochuan; Brons, Jonathan; Fattahi, Hanieh

    2017-01-01

    This is a report on a 100 W, 20 mJ, 1 ps Yb:YAG thin-disk regenerative amplifier. A homemade Yb:YAG thin-disk, Kerr-lens mode-locked oscillator with turn-key performance and microjoule-level pulse energy is used to seed the regenerative chirped-pulse amplifier. The amplifier is placed in airtight housing. It operates at room temperature and exhibits stable operation at a 5 kHz repetition rate, with a pulse-to-pulse stability less than 1%. By employing a 1.5 mm-thick beta barium borate crystal, the frequency of the laser output is doubled to 515 nm, with an average power of 70 W, which corresponds to an optical-to-optical efficiency of 70%. This superior performance makes the system an attractive pump source for optical parametric chirped-pulse amplifiers in the near-infrared and mid-infrared spectral range. Combining the turn-key performance and the superior stability of the regenerative amplifier, the system facilitates the generation of a broadband, CEP-stable seed. Providing the seed and pump of the optical parametric chirped-pulse amplification (OPCPA) from one laser source eliminates the demand of active temporal synchronization between these pulses. This work presents a detailed guide to set up and operate a Yb:YAG thin-disk regenerative amplifier, based on chirped-pulse amplification (CPA), as a pump source for an optical parametric chirped-pulse amplifier. PMID:28745636

  14. Spatiotemporal evolution of cavitation dynamics exhibited by flowing microbubbles during ultrasound exposure.

    PubMed

    Choi, James J; Coussios, Constantin-C

    2012-11-01

    Ultrasound and microbubble-based therapies utilize cavitation to generate bioeffects, yet cavitation dynamics during individual pulses and across consecutive pulses remain poorly understood under physiologically relevant flow conditions. SonoVue(®) microbubbles were made to flow (fluid velocity: 10-40 mm/s) through a vessel in a tissue-mimicking material and were exposed to ultrasound [frequency: 0.5 MHz, peak-rarefactional pressure (PRP): 150-1200 kPa, pulse length: 1-100,000 cycles, pulse repetition frequency (PRF): 1-50 Hz, number of pulses: 10-250]. Radiated emissions were captured on a linear array, and passive acoustic mapping was used to spatiotemporally resolve cavitation events. At low PRPs, stable cavitation was maintained throughout several pulses, thus generating a steady rise in energy with low upstream spatial bias within the focal volume. At high PRPs, inertial cavitation was concentrated in the first 6.3 ± 1.3 ms of a pulse, followed by an energy reduction and high upstream bias. Multiple pulses at PRFs below a flow-dependent critical rate (PRF(crit)) produced predictable and consistent cavitation dynamics. Above the PRF(crit), energy generated was unpredictable and spatially biased. In conclusion, key parameters in microbubble-seeded flow conditions were matched with specific types, magnitudes, distributions, and durations of cavitation; this may help in understanding empirically observed in vivo phenomena and guide future pulse sequence designs.

  15. A study on laser-based ultrasonic technique by the use of guided wave tomographic imaging

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Park, Junpil, E-mail: jpp@pusan.ac.kr; Lim, Juyoung, E-mail: jpp@pusan.ac.kr; Cho, Younho

    2015-03-31

    Guided wave tests are impractical for investigating specimens with limited accessibility and coarse surfaces or geometrically complicated features. A non-contact setup with a laser ultrasonic transmitter and receiver is the classic attractive for guided wave inspection. The present work was done to develop a non-contact guided-wave tomography technique by laser ultrasonic technique in a plate-like structure. A method for Lam wave generation and detection in an aluminum plate with a pulse laser ultrasonic transmitter and a Michelson interferometer receiver has been developed. In the images obtained by laser scanning, the defect shape and area showed good agreement with the actualmore » defect. The proposed approach can be used as a non-contact-based online inspection and monitoring technique.« less

  16. ARGOS - the Laser Star Adaptive Optics for LBT

    NASA Astrophysics Data System (ADS)

    Rabien, S.; Barl, L.; Beckmann, U.; Blümchen, T.; Bonaglia, M.; Borelli, J. L.; Brynnel, J.; Busoni, L.; Carbonaro, L.; Conot, C.; Davies, R.; Deysenroth, M.; Durney, O.; Elberich, M.; Esposito, S.; Gasho, V.; Gässler, W.; Gemperlein, H.; Genzel, R.; Green, R.; Haug, M.; Lloyd Hart, M.; Hubbard, P.; Kanneganti, S.; Kulas, M.; Noenickx, J.; Peter, D.; Quirrenbach, A.; Rademacher, M.; Rix, H. W.; Salinari, P.; Schwab, C.; Storm, J.; Strüder, L.; Thiel, M.; Weigelt, G.; Ziegleder, J.; Orban de Xivry, G.

    2011-09-01

    We will present the design and status of ARGOS - the Laser Guide Star adaptive optics facility for the Large Binocular Telescope. By projecting a constellation of multiple laser guide stars above each of the 8.4m primary mirrors of the LBT, ARGOS in its ground layer mode will enable a wide field adaptive optics correction for multi object spectroscopy. ARGOS implements high power pulsed green lasers and makes use of Rayleigh scattering for the guide star creation. The geometric relations of this setup in guide star height vs. primary diameter are quite comparable to an ELT with sodium guide stars. The use of LBT's adaptive secondary mirror, gated wavefront sensors, a prime focus calibration system and the laser constellation shows several aspects that may be used as pathfinding technology for the planned ELTs. In already planned upgrade steps with a hybrid Sodium-Rayleigh combination ARGOS will enable MCAO and MOAO implementations at LBT allowing unique astronomical observations.

  17. The Role of Pulses in the Dietary Management of Diabetes.

    PubMed

    Ramdath, Dan; Renwick, Simone; Duncan, Alison M

    2016-08-01

    Pulses are highly nutritious foods that are included as part of Canada's Food Guide to promote healthful eating, and they have established health benefits that can contribute to the dietary management of diabetes. A review of studies that have examined the effects of pulse consumption on health outcomes, integral to the management of diabetes, provides credible evidence for improvements in glycemic control, reduction of blood lipids and regulation of body weight. Results from acute feeding trials suggest that postprandial blood glucose response is significantly attenuated by a single pulse serving of between three-quarters and 1 cup. At lower doses, pulses attenuate postprandial blood glucose response more than similar amounts of starchy foods. Long-term pulse consumption of 5 cups per week appears to result consistently in improvements in glycemic control. There is high-quality evidence that supports a role for pulse consumption in the reduction of risk for cardiovascular disease; this provides a sound rationale for the regular incorporation of pulses at about two-thirds of a cup daily in the management of hyperlipidemia in persons with type 2 diabetes. Pulse consumption can contribute to improving satiety, reducing food intake and regulating body weight, which can reduce obesity risk and, in turn, improve diabetes management. Collectively, available evidence provides very good support for a role of regular pulse consumption in the prevention and management of diabetes. Crown Copyright © 2016. Published by Elsevier Inc. All rights reserved.

  18. 76 FR 67621 - Privacy Act of 1974: Implementation of Exemptions; Department of Homeland Security U.S. Customs...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-02

    ...The Department of Homeland Security is giving concurrent notice of a newly established system of records pursuant to the Privacy Act of 1974 for the ``Department of Homeland Security/U.S. Customs and Border Protection-003 Credit/Debit Care Data System of Records'' and this proposed rulemaking. In this proposed rulemaking, the Department proposes to exempt portions of the system of records from one or more provisions of the Privacy Act because of criminal, civil, and administrative enforcement requirements.

  19. A managerial approach to costing fixed assets in health care organizations: the role of depreciation and interest.

    PubMed

    Goldschmidt, Y; Gafni, A

    1991-01-01

    The economic aspect of depreciation and interest on capital are incorporated within a managerial accounting framework by treating both items as imputed charges to be debited to the users of the assets' services. The costs of these services is examined for individual assets that provide either uniform or declining service over the expected life, and for a stock of assets where the character of the individual assets is ignored. By using imputed charges, the hospital's net income is allocated to its sources.

  20. Use of static picture prompts versus video modeling during simulation instruction.

    PubMed

    Alberto, Paul A; Cihak, David F; Gama, Robert I

    2005-01-01

    The purpose of this study was to compare the effectiveness and efficiency of static picture prompts and video modeling as classroom simulation strategies in combination with in vivo community instruction. Students with moderate intellectual disabilities were instructed in the tasks of withdrawing money from an ATM and purchasing items using a debit card. Both simulation strategies were effective and efficient at teaching the skills. The two simulation strategies were not functionally different in terms of number of trials to acquisition, number of errors, and number of instructional sessions to criterion.

  1. Effect of Specimen Thickness on the Creep Response of a Single Crystal Superalloy (Preprint)

    DTIC Science & Technology

    2012-01-01

    0.38mm. 3.1.2. Fractography Figure 5: SEM images of the sheet specimen of thickness 3.18mm creep tested at 760◦C/758MPa, (a) Specimen reconstructed after...with dotted rectangle in (b). To further explore the mechanism behind thickness debit effect, we performed stan- dard fractography using secondary...thickness 3.18mm ruptured after 210hours. 3.2.3. Fractography The SEM image of the reconstructed creep ruptured specimen of thickness 3.18mm is shown in

  2. Enhanced Ultrafast Nonlinear Optics With Microstructure Fibers And Photonic Crystals

    DTIC Science & Technology

    2004-07-01

    NANOHOLES FREQUENCY-TUNABLE ANTI-STOKES LINE EMISSION BY EIGENMODES OF A BIREFRINGENT MICROSTRUCTURE FIBER GENERATION OF FEMTOSECOND ANTI-STOKES PULSES...laser technologies, and ultrafast photonics. ANTI-STOKES GENERATION IN GUIDED MODES OF PHOTONIC-CRYSTAL FIBERS MODIFIED WITH AN ARRAY OF NANOHOLES

  3. The Object Coordination Class Applied to Wave Pulses: Analyzing Student Reasoning in Wave Physics.

    ERIC Educational Resources Information Center

    Wittmann, Michael C.

    2002-01-01

    Analyzes student responses to interview and written questions on wave physics using diSessa and Sherin's coordination class model which suggests that student use of specific reasoning resources is guided by possibly unconscious cues. (Author/MM)

  4. Ultrasound-Guided Pulsed Radiofrequency Stimulation of Posterior Tibial Nerve: A Potential Novel Intervention for Recalcitrant Plantar Fasciitis.

    PubMed

    Wu, Yung-Tsan; Chang, Chih-Ya; Chou, Yu-Ching; Yeh, Chun-Chang; Li, Tsung-Ying; Chu, Heng-Yi; Chen, Liang-Cheng

    2017-05-01

    To evaluate the therapeutic benefit of ultrasound-guided pulsed radiofrequency (PRF) stimulation at the posterior tibial nerve (PTN) in patients with recalcitrant plantar fasciitis (PF). A prospective, randomized, double-blinded, placebo-controlled trial (12-wk follow-up). Outpatient local medical center settings. Patients (N=36) with recalcitrant PF underwent randomization, and all were included in the final data analysis. Patients in the PRF group were treated with 1 dose of ultrasound-guided PRF stimulation at the PTN, and those in the control group received 1 dose of 2% lidocaine, 0.5mL, injected at the PTN under ultrasound guidance. The visual analog scale (first-step and overall pain), American Orthopedic Foot-Ankle Society (AOFAS) ankle-hindfoot scale, and ultrasonographic thickness of the plantar fascia were evaluated at 1, 4, 8, and 12 weeks after treatment. Thirty-six patients (20 feet per group) completed the study. The PRF group had a significantly larger improvement in first-step pain, overall pain, and AOFAS score (all P<.001), as well as plantar fascia thickness (P<.05), compared with those of the control group at all observed time points. This study shows that ultrasound-guided PRF stimulation at the PTN is effective for treating recalcitrant PF. This simple, reproducible method could be a novel strategy for managing recalcitrant PF. Copyright © 2016 American Congress of Rehabilitation Medicine. Published by Elsevier Inc. All rights reserved.

  5. Guided Z mode propagation observed in the OEDIPUS A tethered rocket experiment

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    James, H.G.

    1991-10-01

    The tethered sounding rocket payload OEDIPUS A conducted bistatic propagation experiments on plasma waves in the auroral ionosphere. Synchronized sweeps of the frequency range 0-5 MHz by the 2-W transmitter high-frequency exciter (HEX) on the upper end of the tether and its associated receiver for exciter (REX) on the lower end have produced signatures of quasi-electrostatic waves guided along field-aligned depletions of ambient density. The propagation is in the slow Z mode, between the plasma frequency f{sub p} and the upper hybrid resonance frequency f{sub uhr} when f{sub p} is greater than the cyclotron frequency. The mode identification is basedmore » on payload measurements of f{sub p}. These waves have signal delays of about 1 ms. The delays are much greater than expected for free-space propagation over the transmitter-receiver separation distance which varies up to 960 m during the flight. The transmitted pulses typically appear inside a frequency bandwidth of about 100 kHz just above the plasma frequency, but occasionally occupy most of the available bandwidth, {approx equal}300 kHz, between f{sub p} and f{sub uhr}. The observed delays and the stretching by a factor of 3 of the transmitted 300-{mu}s pulses are accounted for with two-dimensional ray tracing using a complete electromagnetic solution of the hot plasma dispersion relation. Delayed Z mode pulses appear in about 20% of the ionograms. Given the weakness of the HEX transmitter and the abundance of examples obtained during the flight, guiding of natural Z mode emissions in the auroral ionosphere may be efficient and widespread.« less

  6. 175 fs-long pulses from a high-power single-mode Er-doped fiber laser at 1550 nm

    NASA Astrophysics Data System (ADS)

    Elahi, Parviz; Kalaycıoğlu, Hamit; Li, Huihui; Akçaalan, Önder; Ilday, F. Ömer

    2017-11-01

    Development of Er-doped ultrafast lasers have lagged behind the corresponding developments in Yb- and Tm-doped lasers, in particular, fiber lasers. Various applications benefit from operation at a central wavelength of 1.5 μm and its second harmonic, including emerging applications such as 3D processing of silicon and 3D printing based on two-photon polymerization. We report a simple, robust fiber master oscillator power amplifier operating at 1.55 μm, implementing chirp pulse amplification using single-mode fibers for diffraction-limited beam quality. The laser generates 80 nJ pulses at a repetition rate of 43 MHz, corresponding to an average power of 3.5 W, which can be compressed down to 175 fs. The generation of short pulses was achieved using a design which is guided by numerical simulations of pulse propagation and amplification and manages to overturn gain narrowing with self-phase modulation, without invoking excessive Raman scattering processes. The seed source for the two-stage amplifier is a dispersion-managed passively mode-locked oscillator, which generates a ∼40 nm-wide spectrum and 1.7-ps linearly chirped pulses.

  7. A Fiber Bragg Grating Sensor for Radial Artery Pulse Waveform Measurement.

    PubMed

    Jia, Dagong; Chao, Jing; Li, Shuai; Zhang, Hongxia; Yan, Yingzhan; Liu, Tiegen; Sun, Ye

    2018-04-01

    In this paper, we report the design and experimental validation of a novel optical sensor for radial artery pulse measurement based on fiber Bragg grating (FBG) and lever amplification mechanism. Pulse waveform analysis is a diagnostic tool for clinical examination and disease diagnosis. High fidelity radial artery pulse waveform has been investigated in clinical studies for estimating central aortic pressure, which is proved to be predictors of cardiovascular diseases. As a three-dimensional cylinder, the radial artery needs to be examined from different locations to achieve optimal pulse waveform for estimation and diagnosis. The proposed optical sensing system is featured as high sensitivity and immunity to electromagnetic interference for multilocation radial artery pulse waveform measurement. The FBG sensor can achieve the sensitivity of 8.236 nm/N, which is comparable to a commonly used electrical sensor. This FBG-based system can provide high accurate measurement, and the key characteristic parameters can be then extracted from the raw signals for clinical applications. The detecting performance is validated through experiments guided by physicians. In the experimental validation, we applied this sensor to measure the pulse waveforms at various positions and depths of the radial artery in the wrist according to the diagnostic requirements. The results demonstrate the high feasibility of using optical systems for physiological measurement and using this FBG sensor for radial artery pulse waveform in clinical applications.

  8. Development of variable-rate sprayer for nursery liner applications

    USDA-ARS?s Scientific Manuscript database

    Sensor-guided application technologies are needed to achieve constant spray deposition for the rapid growth of nursery liner trees during a growing season. An experimental real-time variable-rate sprayer that implemented 20 Hz ultrasonic sensors and pulse width modulation (PWM) solenoid valve-contro...

  9. Intraoperative diagnostics and elimination of residual microtumours with plasmonic nanobubbles

    NASA Astrophysics Data System (ADS)

    Lukianova-Hleb, Ekaterina Y.; Kim, Yoo-Shin; Belatsarkouski, Ihor; Gillenwater, Ann M.; O'Neill, Brian E.; Lapotko, Dmitri O.

    2016-06-01

    Failure of cancer surgery to intraoperatively detect and eliminate microscopic residual disease (MRD) causes lethal recurrence and metastases, and the removal of important normal tissues causes excessive morbidity. Here, we show that a plasmonic nanobubble (PNB), a non-stationary laser pulse-activated nanoevent, intraoperatively detects and eliminates MRD in the surgical bed. PNBs were generated in vivo in head and neck cancer cells by systemically targeting tumours with gold colloids and locally applying near-infrared, low-energy short laser pulses, and were simultaneously detected with an acoustic probe. In mouse models, between 3 and 30 residual cancer cells and MRD (undetectable with current methods) were non-invasively detected up to 4 mm deep in the surgical bed within 1 ms. In resectable MRD, PNB-guided surgery prevented local recurrence and delivered 100% tumour-free survival. In unresectable MRD, PNB nanosurgery improved survival twofold compared with standard surgery. Our results show that PNB-guided surgery and nanosurgery can rapidly and precisely detect and remove MRD in simple intraoperative procedures.

  10. A pulse coding and decoding strategy to perform Lamb wave inspections using simultaneously multiple actuators

    NASA Astrophysics Data System (ADS)

    De Marchi, Luca; Marzani, Alessandro; Moll, Jochen; Kudela, Paweł; Radzieński, Maciej; Ostachowicz, Wiesław

    2017-07-01

    The performance of Lamb wave based monitoring systems, both in terms of diagnosis time and data complexity, can be enhanced by increasing the number of transducers used to actuate simultaneously the guided waves in the inspected medium. However, in case of multiple simultaneously-operated actuators the interference among the excited wave modes within the acquired signals has to be considered for the further processing. To this aim, in this work a code division strategy based on the Warped Frequency Transform is presented. At first, the proposed procedure encodes actuation pulses using Gold sequences. Next, for each considered actuator the acquired signals are compensated from dispersion by cross correlating the warped version of the actuated and received signals. Compensated signals form the base for a final wavenumber imaging meant at emphasizing defects and or anomalies by removing incident wavefield and edge reflections. The proposed strategy is tested numerically, and validated through an experiment in which guided waves are actuated in a plate by four piezoelectric transducers operating simultaneously.

  11. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Barnard, John J.; Schenkel, Thomas

    Intense, pulsed ion beams locally heat materials and deliver dense electronic excitations that can induce material modifications and phase transitions. Material properties can potentially be stabilized by rapid quenching. Pulsed ion beams with pulse lengths of order ns have recently become available for materials processing. Here, we optimize mask geometries for local modification of materials by intense ion pulses. The goal is to rapidly excite targets volumetrically to the point where a phase transition or local lattice reconstruction is induced followed by rapid cooling that stabilizes desired material's properties fast enough before the target is altered or damaged by, e.g.,more » hydrodynamic expansion. By using a mask, the longitudinal dimension can be large compared to the transverse dimension, allowing the possibility of rapid transverse cooling. We performed HYDRA simulations that calculate peak temperatures for a series of excitation conditions and cooling rates of silicon targets with micro-structured masks and compare these to a simple analytical model. In conclusion, the model gives scaling laws that can guide the design of targets over a wide range of pulsed ion beam parameters.« less

  12. Optimization of ultrasound parameters of myocardial cavitation microlesions for therapeutic application.

    PubMed

    Miller, Douglas L; Dou, Chunyan; Owens, Gabe E; Kripfgans, Oliver D

    2014-06-01

    Intermittent high intensity ultrasound scanning with contrast microbubbles can induce scattered cavitation microlesions in the myocardium, which may be of value for tissue reduction therapy. Anesthetized rats were treated in a heated water bath with 1.5 MHz focused ultrasound pulses, guided by an 8 MHz imaging transducer. The relative efficacy with 2 or 4 MPa pulses, 1:4 or 1:8 trigger intervals and 5 or 10 cycle pulses was explored in six groups. Electrocardiogram premature complexes (PCs) induced by the triggered pulse bursts were counted, and Evans blue stained cardiomyocyte scores (SCSs) were obtained. The increase from 2 to 4 MPa produced significant increases in PCs and SCSs and eliminated an anticipated decline in the rate of PC induction with time, which might hinder therapeutic efficacy. Increased intervals and pulse durations did not yield significant increases in the effects. The results suggest that cavitation microlesion production can be refined and potentially lead to a clinically robust therapeutic method. Copyright © 2014 World Federation for Ultrasound in Medicine & Biology. Published by Elsevier Inc. All rights reserved.

  13. Selective Removal of Demineralization Using Near Infrared Cross Polarization Reflectance and a Carbon Dioxide Laser.

    PubMed

    Chan, Kenneth H; Fried, Daniel

    2012-02-09

    Lasers can ablate/remove tissue in a non-contact mode of operation and a pulsed laser beam does not interfere with the ability to image the tooth surface, therefore lasers are ideally suited for integration with imaging devices for image-guided ablation. Laser energy can be rapidly and efficiently delivered to tooth surfaces using a digitally controlled laser beam scanning system for precise and selective laser ablation with minimal loss of healthy tissues. Under the appropriate irradiation conditions such laser energy can induce beneficial chemical and morphological changes in the walls of the drilled cavity that can increase resistance to further dental decay and produce surfaces with enhanced adhesive properties to restorative materials. Previous studies have shown that images acquired using near-IR transillumination, optical coherence tomography and fluorescence can be used to guide the laser for selective removal of demineralized enamel. Recent studies have shown that NIR reflectance measurements at 1470-nm can be used to obtain images of enamel demineralization with very high contrast. The purpose of this study was to demonstrate that image guided ablation of occlusal lesions can be successfully carried out using a NIR reflectance imaging system coupled with a carbon dioxide laser operating at 9.3-μm with high pulse repetition rates.

  14. Pulsed cavitational ultrasound for non-invasive chordal cutting guided by real-time 3D echocardiography.

    PubMed

    Villemain, Olivier; Kwiecinski, Wojciech; Bel, Alain; Robin, Justine; Bruneval, Patrick; Arnal, Bastien; Tanter, Mickael; Pernot, Mathieu; Messas, Emmanuel

    2016-10-01

    Basal chordae surgical section has been shown to be effective in reducing ischaemic mitral regurgitation (IMR). Achieving this section by non-invasive mean can considerably decrease the morbidity of this intervention on already infarcted myocardium. We investigated in vitro and in vivo the feasibility and safety of pulsed cavitational focused ultrasound (histotripsy) for non-invasive chordal cutting guided by real-time 3D echocardiography. Experiments were performed on 12 sheep hearts, 5 in vitro on explanted sheep hearts and 7 in vivo on beating sheep hearts. In vitro, the mitral valve (MV) apparatus including basal and marginal chordae was removed and fixed on a holder in a water tank. High-intensity ultrasound pulses were emitted from the therapeutic device (1-MHz focused transducer, pulses of 8 µs duration, peak negative pressure of 17 MPa, repetition frequency of 100 Hz), placed at a distance of 64 mm under 3D echocardiography guidance. In vivo, after sternotomy, the same therapeutic device was applied on the beating heart. We analysed MV coaptation and chordae by real-time 3D echocardiography before and after basal chordal cutting. After sacrifice, the MV apparatus were harvested for anatomical and histological post-mortem explorations to confirm the section of the chordae. In vitro, all chordae were completely cut after a mean procedure duration of 5.5 ± 2.5 min. The procedure duration was found to increase linearly with the chordae diameter. In vivo, the central basal chordae of the anterior leaflet were completely cut. The mean procedure duration was 20 ± 9 min (min = 14, max = 26). The sectioned chordae was visible on echocardiography, and MV coaptation remained normal with no significant mitral regurgitation. Anatomical and histological post-mortem explorations of the hearts confirmed the section of the chordae. Histotripsy guided by 3D echo achieved successfully to cut MV chordae in vitro and in vivo in beating heart. We hope that this technique will open the door in the near future to the non-invasive treatment of functional IMR. Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2016. For permissions please email: journals.permissions@oup.com.

  15. High-speed optical phase-shifting apparatus

    DOEpatents

    Zortman, William A.

    2016-11-08

    An optical phase shifter includes an optical waveguide, a plurality of partial phase shifting elements arranged sequentially, and control circuitry electrically coupled to the partial phase shifting elements. The control circuitry is adapted to provide an activating signal to each of the N partial phase shifting elements such that the signal is delayed by a clock cycle between adjacent partial phase shifting elements in the sequence. The transit time for a guided optical pulse train between the input edges of consecutive partial phase shifting elements in the sequence is arranged to be equal to a clock cycle, thereby enabling pipelined processing of the optical pulses.

  16. Intravenous injection of indocyanine green results in an artificial transient desaturation by pulse oximetry.

    PubMed

    Ediriwickrema, Lilangi S; Francis, Jasmine H; Arslan-Carlon, Vittoria; Dalecki, Paul H; Brodie, Scott E; Marr, Brian P; Abramson, David H

    2015-01-01

    To describe a case series of transient oxygen desaturation measured by pulse oximetry during the intravenous infusion of indocyanine green to enhance transpupillary thermotherapy in treating retinoblastoma after ophthalmic artery chemosurgery. Retrospective descriptive case series. The intravenous administration of indocyanine green for ophthalmic angiography resulted in a transient drop in oxygen saturation as measured by Nellcor fingertip pulse oximetry in three children with retinoblastoma receiving indocyanine green-guided transpupillary thermotherapy. The magnitude of reduction ranged from 92% to 94% from an initial reading of 99% to 100% in each case, with an average duration of 3 minutes. Concurrent measurement of blood pressure, pulse, and expired CO2 showed no changes during this process. Administration of intravenous indocyanine green resulted in a transient desaturation by oximetry during transpupillary thermotherapy for children with retinoblastoma under anesthesia because of the fluorescent dye's absorption of red light in a manner similar to that of deoxygenated hemoglobin, thereby leading to transient instrument misinterpretation and miscalculation of arterial oxygenation.

  17. Construction of the Helsinki University of Technology (HUT) pulsed positron beam

    NASA Astrophysics Data System (ADS)

    Fallström, K.; Laine, T.

    1999-08-01

    We are constructing a pulsed positron beam facility for lifetime measurements in thin surface layers. Our beam system comprises a 22Na positron source and a tungsten foil moderator followed by a prebuncher and a chopper. A double-drift buncher will compress the beam into 120-ps pulses at the target. The end energy of the positron beam can be adjusted between 3 keV and 30 keV by changing the potential of the source end of the beam. The bunching electronics and most of the beam guiding magnets are also floating at the high voltage. The sample is at ground potential to facilitate variable temperature measurements. With a test source of 6 mCi 22Na we get a prebunched beam intensity of 4×10 3 positrons per second in 1.5-ns wide pulses (the bunching frequency is 33.33 MHz). We are currently testing the chopper and the following buncher stages and building the final accelerator/decelerator system.

  18. Conditioned Side Effects Induced by Cancer Chemotherapy: Prevention Through Behavioral Treatment.

    ERIC Educational Resources Information Center

    Burish, Thomas G.; And Others

    1987-01-01

    Studied cancer patients (N=24) in order to determine whether conditioned nausea and vomiting could be delayed or prevented. Indicated that patients receiving progressive muscle relaxation training and guided imagery had significantly less nausea and vomiting and significanty lower blood pressures, pulse rates, and dysphoria, especially anxiety,…

  19. Calibration of a speckle-based compressive sensing receiver

    NASA Astrophysics Data System (ADS)

    Sefler, George A.; Shaw, T. Justin; Stapleton, Andrew D.; Valley, George C.

    2017-02-01

    Optical speckle in a multimode waveguide has been proposed to perform the function of a compressive sensing (CS) measurement matrix (MM) in a receiver for GHz-band radio frequency (RF) signals. Unlike other devices used for the CS MM, e.g. the digital micromirror device (DMD) used in the single pixel camera, the elements of the speckle MM are not known before use and must be measured and calibrated. In our system, the RF signal is modulated on a repetitively pulsed chirped wavelength laser source, generated from mode-locked laser pulses that have been dispersed in time or from an electrically addressed distributed Bragg reflector laser. Next, the optical beam with RF propagates through a multimode fiber or waveguide, which applies different weights in wavelength (or equivalently time) and space and performs the function of the CS MM. The output of the guide is directed to or imaged on a bank of photodiodes with integration time set to the pulse length of the chirp waveform. The output of each photodiode is digitized by an analog-to-digital converter (ADC), and the data from these ADCs are used to form the CS measurement vector. Accurate recovery of the RF signal from CS measurements depends critically on knowledge of the weights in the MM. Here we present results using a stable wavelength laser source to probe the guide.

  20. New description of charged particle propagation in random magnetic fields

    NASA Technical Reports Server (NTRS)

    Earl, James A.

    1994-01-01

    When charged particles spiral along a large constant magnetic field, their trajectories are scattered by random components that are superposed on the guiding field. In the simplest analysis of this situation, scattering causes the particles to diffuse parallel to the guiding field. At the next level of approximation, moving pulses that correspond to a coherent mode of propagation are present, but they are represented by delta-functions whose infinitely narrow width makes no sense physically and is inconsistent with the finite duration of coherent pulses observed in solar energetic particle events. To derive a more realistic description, the transport problem is formulated in terms of 4 x 4 matrices, which derive from a representation of the particle distribution function in terms of eigenfunctions of the scattering operator, and which lead to useful approximations that give explicit predictions of the detailed evolution not only of the coherent pulses, but also of the diffusive wake. More specifically, the new description embodies a simple convolution of a narrow Gaussian with the solutions above that involve delta-functions, but with a slightly reduced coherent velocity. The validity of these approximations, which can easily be calculated on a desktop computer, has been exhaustively confirmed by comparison with results of Monte Carlo simulations which kept track of 50 million particles and which were carried out on the Maspar computer at Goddard Space Flight Center.

  1. A magnetic flux leakage and magnetostrictive guided wave hybrid transducer for detecting bridge cables.

    PubMed

    Xu, Jiang; Wu, Xinjun; Cheng, Cheng; Ben, Anran

    2012-01-01

    Condition assessment of cables has gained considerable attention for the bridge safety. A magnetic flux leakage and magnetostrictive guided wave hybrid transducer is provided to inspect bridge cables. The similarities and differences between the two methods are investigated. The hybrid transducer for bridge cables consists of an aluminum framework, climbing modules, embedded magnetizers and a ribbon coil. The static axial magnetic field provided by the magnetizers meets the needs of the magnetic flux leakage testing and the magnetostrictive guided wave testing. The magnetizers also provide the attraction for the climbing modules. In the magnetic flux leakage testing for the free length of cable, the coil induces the axial leakage magnetic field. In the magnetostrictive guided wave testing for the anchorage zone, the coil provides a pulse high power variational magnetic field for generating guided waves; the coil induces the magnetic field variation for receiving guided waves. The experimental results show that the transducer with the corresponding inspection system could be applied to detect the broken wires in the free length and in the anchorage zone of bridge cables.

  2. A Magnetic Flux Leakage and Magnetostrictive Guided Wave Hybrid Transducer for Detecting Bridge Cables

    PubMed Central

    Xu, Jiang; Wu, Xinjun; Cheng, Cheng; Ben, Anran

    2012-01-01

    Condition assessment of cables has gained considerable attention for the bridge safety. A magnetic flux leakage and magnetostrictive guided wave hybrid transducer is provided to inspect bridge cables. The similarities and differences between the two methods are investigated. The hybrid transducer for bridge cables consists of an aluminum framework, climbing modules, embedded magnetizers and a ribbon coil. The static axial magnetic field provided by the magnetizers meets the needs of the magnetic flux leakage testing and the magnetostrictive guided wave testing. The magnetizers also provide the attraction for the climbing modules. In the magnetic flux leakage testing for the free length of cable, the coil induces the axial leakage magnetic field. In the magnetostrictive guided wave testing for the anchorage zone, the coil provides a pulse high power variational magnetic field for generating guided waves; the coil induces the magnetic field variation for receiving guided waves. The experimental results show that the transducer with the corresponding inspection system could be applied to detect the broken wires in the free length and in the anchorage zone of bridge cables. PMID:22368483

  3. THE ROLE OF PSYCHOTHERAPY IN ALLERGY—Credits and Debits

    PubMed Central

    Sirmay, Elizabeth A.

    1953-01-01

    Psychological problems play an important role in the production and exacerbation of allergic disease, just as they do in other illnesses, especially those of a chronic nature entailing economic and social problems. Some psychotherapy is implicit in the practice of all physicians. While most patients make satisfactory progress with whatever treatment is outlined, a few do not, and they may be helped if a little extra time is taken to investigate and rebalance their mental environment. In the treatment of patients with allergic disease, dealing with emotional problems is considered as adjunctive to specific desensitization. PMID:13042681

  4. Acute effects of pulsed-laser irradiation on the arterial wall

    NASA Astrophysics Data System (ADS)

    Nakamura, Fumitaka; Kvasnicka, Jan; Lu, Hanjiang; Geschwind, Herbert J.; Levame, Micheline; Bousbaa, Hassan; Lange, Francoise

    1992-08-01

    Pulsed laser coronary angioplasty with an excimer or a holmium-yttrium-aluminum-garnet (Ho:YAG) laser may become an alternative treatment for patients with coronary artery disease. However, little is known about its acute consequences on the normal arterial wall. This study was designed to examine the acute histologic consequences of these two pulsed lasers on the arterial wall of normal iliac arteries in rabbits. Irradiation with each laser was performed in 15 normal iliac sites on eight male New Zealand white rabbits. The excimer laser was operated at 308 nm, 25 Hz, 50 mJ/mm2/pulse, and 135 nsec/pulse and the Ho:YAG laser was operated at 2.1 micrometers , 3/5 Hz, 400 mJ/pulse, and 250 microsecond(s) ec/pulse. The excimer and Ho:YAG laser were coupled into a multifiber wire-guided catheter of 1.4 and 1.5 mm diameter, respectively. The sites irradiated with excimer or Ho:YAG laser had the same kinds of histologic features, consisting of exfoliation of the endothelium, disorganization of internal elastic lamina, localized necrosis of vascular smooth muscle cells, and fissures in the medial layer. However, the sites irradiated with excimer laser had lower grading scores than those irradiated with Ho:YAG laser (p < 0.05). Laser irradiation with excimer or Ho:YAG laser of normal arteries results in localized mechanical vascular injury.

  5. Mining CRRES IDM Pulse Data and CRRES Environmental Data to Improve Spacecraft Charging/Discharging Models and Guidelines

    NASA Technical Reports Server (NTRS)

    Brautigam, D. H.; Frederickson, A. R.

    2004-01-01

    One can truly predict the charging and pulsing in space over a year's time using only the physics that worked for periods of an hour and less in prior publications. All portions of the task were achieved, including the optional portion of determining a value for conductivity that best .t the data. Fortran statements were developed that are required for the NUMIT runs to work with this kind of data from space. In addition to developing the Fortran for NUMIT, simple correlations between the IDM pulsing history and the space radiation were observed because we now have a better characterization of the space radiation. The study showed that: (1) the new methods for measurement of charge storage and conduction in insulators provide the correct values to use for prediction of charging and pulsing in space; (2) the methods in NUMIT that worked well for time durations less than hours now work well for durations of months; (3) an average spectrum such as AE8 is probably not a good guide for predicting pulsing in space one must take time dependence into account in order to understand insulator pulsing; and (4) the old method for predicting pulse rates in space that was based on the CRRES data could be improved to include dependencies on material parameters.

  6. Treatment of Refractory Idiopathic Supraorbital Neuralgia Using Percutaneous Pulsed Radiofrequency.

    PubMed

    Luo, Fang; Lu, Jingjing; Ji, Nan

    2018-02-26

    No ideal therapeutic method currently exists for refractory idiopathic supraorbital neuralgia patients who do not respond to conservative therapy, including medications and nerve blocks. Pulsed radiofrequency is a neuromodulation technique that does not produce sequelae of nerve damage after treatment. However, the efficacy of percutaneous pulsed radiofrequency for the treatment of refractory idiopathic supraorbital neuralgia is still not clear. The purpose of our study was to evaluate the efficacy and safety of pulsed radiofrequency treatment of the supraorbital nerve for refractory supraorbital neuralgia patients. We prospectively investigated the long-term effects of ultrasound-guided percutaneous pulsed radiofrequency in the treatment of 22 refractory idiopathic supraorbital neuralgia patients. A reduction in the verbal pain numeric rating scale score of more than 50% was used as the standard of effectiveness. The effectiveness rates at different time points within 2 years were calculated. After a single pulsed radiofrequency treatment, the effectiveness rate at 1 and 3 months was 77%, and the rates at 6 months, 1 year, and 2 years were 73%, 64%, and 50%, respectively. Except for a small portion of patients (23%) who experienced mild upper eyelid ecchymosis that gradually disappeared after approximately 2 weeks, no obvious complications were observed. In conclusion, the results of our study demonstrate that for patients with refractory idiopathic supraorbital neuralgia, percutaneous pulsed radiofrequency may be an effective and safe treatment choice. © 2018 World Institute of Pain.

  7. Non-periodic multi-slit masking for a single counter rotating 2-disc chopper and channeling guides for high resolution and high intensity neutron TOF spectroscopy

    NASA Astrophysics Data System (ADS)

    Bartkowiak, M.; Hofmann, T.; Stüßer, N.

    2017-02-01

    Energy resolution is an important design goal for time-of-flight instruments and neutron spectroscopy. For high-resolution applications, it is required that the burst times of choppers be short, going down to the μs-range. To produce short pulses while maintaining high neutron flux, we propose beam masks with more than two slits on a counter-rotating 2-disc chopper, behind specially adapted focusing multi-channel guides. A novel non-regular arrangement of the slits ensures that the beam opens only once per chopper cycle, when the masks are congruently aligned. Additionally, beam splitting and intensity focusing by guides before and after the chopper position provide high intensities even for small samples. Phase-space analysis and Monte Carlo simulations on examples of four-slit masks with adapted guide geometries show the potential of the proposed setup.

  8. Systematic neutron guide misalignment for an accelerator-driven spallation neutron source

    NASA Astrophysics Data System (ADS)

    Zendler, C.; Bentley, P. M.

    2016-08-01

    The European Spallation Source (ESS) is a long pulse spallation neutron source that is currently under construction in Lund, Sweden. A considerable fraction of the 22 planned instruments extend as far as 75-150 m from the source. In such long beam lines, misalignment between neutron guide segments can decrease the neutron transmission significantly. In addition to a random misalignment from installation tolerances, the ground on which ESS is built can be expected to sink with time, and thus shift the neutron guide segments further away from the ideal alignment axis in a systematic way. These systematic errors are correlated to the ground structure, position of buildings and shielding installation. Since the largest deformation is expected close to the target, even short instruments might be noticeably affected. In this study, the effect of this systematic misalignment on short and long ESS beam lines is analyzed, and a possible mitigation by overillumination of subsequent guide sections investigated.

  9. The Utilization of Robotic Pets in Dementia Care.

    PubMed

    Petersen, Sandra; Houston, Susan; Qin, Huanying; Tague, Corey; Studley, Jill

    2017-01-01

    Behavioral problems may affect individuals with dementia, increasing the cost and burden of care. Pet therapy has been known to be emotionally beneficial for many years. Robotic pets have been shown to have similar positive effects without the negative aspects of traditional pets. Robotic pet therapy offers an alternative to traditional pet therapy. The study rigorously assesses the effectiveness of the PARO robotic pet, an FDA approved biofeedback device, in treating dementia-related symptoms. A randomized block design with repeated measurements guided the study. Before and after measures included reliable, valid tools such as: RAID, CSDD, GDS, pulse rate, pulse oximetry, and GSR. Participants interacted with the PARO robotic pet, and the control group received standard activity programs. Five urban secure dementia units comprised the setting. 61 patients, with 77% females, average 83.4 years in age, were randomized into control and treatment groups. Compared to the control group, RAID, CSDD, GSR, and pulse oximetry were increased in the treatment group, while pulse rate, pain medication, and psychoactive medication use were decreased. The changes in GSR, pulse oximetry, and pulse rate over time were plotted for both groups. The difference between groups was consistent throughout the 12-week study for pulse oximetry and pulse rate, while GSR had several weeks when changes were similar between groups. Treatment with the PARO robot decreased stress and anxiety in the treatment group and resulted in reductions in the use of psychoactive medications and pain medications in elderly clients with dementia.

  10. The Utilization of Robotic Pets in Dementia Care

    PubMed Central

    Petersen, Sandra; Houston, Susan; Qin, Huanying; Tague, Corey; Studley, Jill

    2016-01-01

    Background: Behavioral problems may affect individuals with dementia, increasing the cost and burden of care. Pet therapy has been known to be emotionally beneficial for many years. Robotic pets have been shown to have similar positive effects without the negative aspects of traditional pets. Robotic pet therapy offers an alternative to traditional pet therapy. Objective: The study rigorously assesses the effectiveness of the PARO robotic pet, an FDA approved biofeedback device, in treating dementia-related symptoms. Methods: A randomized block design with repeated measurements guided the study. Before and after measures included reliable, valid tools such as: RAID, CSDD, GDS, pulse rate, pulse oximetry, and GSR. Participants interacted with the PARO robotic pet, and the control group received standard activity programs. Five urban secure dementia units comprised the setting. Results: 61 patients, with 77% females, average 83.4 years in age, were randomized into control and treatment groups. Compared to the control group, RAID, CSDD, GSR, and pulse oximetry were increased in the treatment group, while pulse rate, pain medication, and psychoactive medication use were decreased. The changes in GSR, pulse oximetry, and pulse rate over time were plotted for both groups. The difference between groups was consistent throughout the 12-week study for pulse oximetry and pulse rate, while GSR had several weeks when changes were similar between groups. Conclusions: Treatment with the PARO robot decreased stress and anxiety in the treatment group and resulted in reductions in the use of psychoactive medications and pain medications in elderly clients with dementia. PMID:27716673

  11. Photonic Switching Devices Using Light Bullets

    NASA Technical Reports Server (NTRS)

    Goorjian, Peter M. (Inventor)

    1997-01-01

    The present invention is directed toward a unique ultra-fast, all-optical switching device or switch made with readily available, relatively inexpensive, highly nonlinear photonic glasses. These photonic glasses have a sufficiently negative group velocity dispersion and high nonlinear index of refraction to support stable light bullets. The light bullets counterpropagate through, and interact within the waveguide to selectively change each others' directions of propagation into predetermined channels. In one embodiment, the switch utilizes a rectangularly planar slab waveguide, and further includes two central channels and a plurality of lateral channels for guiding the light bullets into and out of the waveguide. One advantage presented by the present all-optical switching device lies in its practical use of light bullets, thus preventing the degeneration of the pulses due to dispersion and diffraction at the front and back of the pulses. Another feature of the switching device is the relative insensitivity of the collision process to the time difference in which the counter-propagating pulses enter the waveguide. since. contrary to conventional co-propagating spatial solitons, the relative phase of the colliding pulses does not affect the interaction of these pulses. Yet another feature of the present all-optical switching device is the selection of the light pulse parameters which enables the generation of light bullets in highly nonlinear glasses.

  12. Graphene-doped polymer nanofibers for low-threshold nonlinear optical waveguiding

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Meng, Chao; Yu, Shao-Liang; Wang, Hong -Qing

    Graphene-doped polymer nanofibers are fabricated by taper drawing of solvated polyvinyl alcohol doped with liquid-phase exfoliated graphene flakes. Nanofibers drawn this way typically have diameters measured in hundreds of nanometers and lengths in tens of millimeters; they show excellent uniformity and surface smoothness for optical waveguiding. Owing to their tightly confined waveguiding behavior, light–matter interaction in these subwavelength-diameter nanofibers is significantly enhanced. Using approximately 1350-nm-wavelength femto-second pulses, we demonstrate saturable absorption behavior in these nanofibers with a saturation threshold down to 0.25 pJ pulse -1 (peak power ~1.3 W). Additionally, using 1064-nm-wavelength nanosecond pulses as switching light, we show all-opticalmore » modulation of a 1550-nm-wavelength signal light guided along a single nanofiber with a switching peak power of ~3.2 W.« less

  13. Measurement and Modeling of Dispersive Pulse Propagation in Drawn Wire Waveguides

    NASA Technical Reports Server (NTRS)

    Madaras, Eric I.; Kohl, Thomas W.; Rogers, Wayne P.

    1995-01-01

    An analytical model of dispersive pulse propagation in semi-infinite cylinders due to transient axially symmetric end conditions has been experimentally investigated. Specifically, the dispersive propagation of the first axially symmetric longitudinal mode in thin wire waveguides, which have ends in butt contact with longitudinal piezoelectric ultrasonic transducers, is examined. The method allows for prediction of a propagated waveform given a measured source waveform, together with the material properties of the cylinder. Alternatively, the source waveform can be extracted from measurement of the propagated waveform. The material properties required for implementation of the pulse propagation model are determined using guided wave phase velocity measurements. Hard tempered aluminum 1100 and 304 stainless steel wires, with 127, 305, and 406 micron diam., were examined. In general, the drawn wires were found to behave as transversely isotropic media.

  14. Measurement and modeling of dispersive pulse propagation in draw wire waveguides

    NASA Technical Reports Server (NTRS)

    Madaras, Eric I.; Kohl, Thomas W.; Rogers, Wayne P.

    1995-01-01

    An analytical model of dispersive pulse propagation in semi-infinite cylinders due to transient axially symmetric end conditions has been experimentally investigated. Specifically, the dispersive propagation of the first axially symmetric longitudinal mode in thin wire waveguides, which have ends in butt contact with longitudinal piezoelectric ultrasonic transducers, is examined. The method allows for prediction of a propagated waveform given a measured source waveform, together with the material properties of the cylinder. Alternatively, the source waveform can be extracted from measurement of the propagated waveform. The material properties required for implementation of the pulse propagation model are determined using guided wave phase velocity measurements. Hard tempered aluminum 1100 and 304 stainless steel wires, with 127, 305, and 406 micron diam., were examined. In general, the drawn wires were found to behave as transversely isotropic media.

  15. Graphene-doped polymer nanofibers for low-threshold nonlinear optical waveguiding

    DOE PAGES

    Meng, Chao; Yu, Shao-Liang; Wang, Hong -Qing; ...

    2015-11-06

    Graphene-doped polymer nanofibers are fabricated by taper drawing of solvated polyvinyl alcohol doped with liquid-phase exfoliated graphene flakes. Nanofibers drawn this way typically have diameters measured in hundreds of nanometers and lengths in tens of millimeters; they show excellent uniformity and surface smoothness for optical waveguiding. Owing to their tightly confined waveguiding behavior, light–matter interaction in these subwavelength-diameter nanofibers is significantly enhanced. Using approximately 1350-nm-wavelength femto-second pulses, we demonstrate saturable absorption behavior in these nanofibers with a saturation threshold down to 0.25 pJ pulse -1 (peak power ~1.3 W). Additionally, using 1064-nm-wavelength nanosecond pulses as switching light, we show all-opticalmore » modulation of a 1550-nm-wavelength signal light guided along a single nanofiber with a switching peak power of ~3.2 W.« less

  16. A Miniature Forward-imaging B-scan Optical Coherence Tomography Probe to Guide Real-time Laser Ablation

    PubMed Central

    Li, Zhuoyan; Shen, Jin H.; Kozub, John A.; Prasad, Ratna; Lu, Pengcheng; Joos, Karen M.

    2014-01-01

    Background and Objective Investigations have shown that pulsed lasers tuned to 6.1 μm in wavelength are capable of ablating ocular and neural tissue with minimal collateral damage. This study investigated whether a miniature B-scan forward-imaging optical coherence tomography (OCT) probe can be combined with the laser to provide real-time visual feedback during laser incisions. Study Design/Methods and Materials A miniature 25-gauge B-scan forward-imaging OCT probe was developed and combined with a 250 μm hollow-glass waveguide to permit delivery of 6.1 μm laser energy. A gelatin mixture and both porcine corneal and retinal tissues were simultaneously imaged and lased (6.1 μm, 10 Hz, 0.4-0.7 mJ) through air. The ablation studies were observed and recorded in real time. The crater dimensions were measured using OCT imaging software (Bioptigen, Durham, NC). Histological analysis was performed on the ocular tissues. Results The combined miniature forward-imaging OCT and mid-infrared laser-delivery probe successfully imaged real-time tissue ablation in gelatin, corneal tissue, and retinal tissue. Application of a constant number of 60 pulses at 0.5 mJ/pulse to the gelatin resulted in a mean crater depth of 123 ± 15 μm. For the corneal tissue, there was a significant correlation between the number of pulses used and depth of the lased hole (Pearson correlation coefficient = 0.82; P = 0.0002). Histological analysis of the cornea and retina tissues showed discrete holes with minimal thermal damage. Conclusions A combined miniature OCT and laser -delivery probe can monitor real-time tissue laser ablation. With additional testing and improvements, this novel instrument has the future possibility of effectively guiding surgeries by simultaneously imaging and ablating tissue. PMID:24648326

  17. Tantalum pentoxide waveguides and microresonators for VECSEL based frequency combs

    NASA Astrophysics Data System (ADS)

    Chen Sverre, T.; Woods, J. R. C.; Shaw, E. A.; Hua, Ping; Apostolopoulos, V.; Wilkinson, J. S.; Tropper, A. C.

    2018-02-01

    Tantalum pentoxide (Ta2O5) is a promising material for mass-producible, multi-functional, integrated photonics circuits on silicon, exhibiting robust electrical, mechanical and thermal properties, as well as good CMOS compatibility. In addition, Ta2O5 has been reported to demonstrate a non-linear response comparable to that of chalcogenide glass, in the region of 3-6 times larger than that of materials such as silica (SiO2) or silicon nitride (Si3N4). In contrast to Si-based dielectrics, it will accept trivalent ytterbium and erbium dopant ions, opening the possibility of on-chip amplification. The high refractive index of Ta2O5 is consistent with small guided mode cross-section area, and allows the construction of micro-ring resonators. Propagation losses as low as 0.2 dB=cm have been reported. In this paper we describe the design of a planar Ta2O5 waveguides optimised for the generation of coherent continuum with near infrared pulse trains at kW peak powers. The Pulse Repetition Frequency (PRF) of the VECSEL can be tuned to a sub-harmonic of the planar micro-ring and the optical pump power applied to the VECSEL can be adjusted so that mode-matching of the VECSEL pulse train with the micro-ring resonator can be achieved. We shall describe the fabrication of Ta2O5 guiding structures, and the characterisation of their nonlinear and other optical properties. Characterisation with conventional lasers will be used to assess the degree of coherent spectral broadening likely to be achievable using these devices when driven by mode-locked VECSELs operating near the current state-of- art for pulse energy and duration.

  18. Optical coherence tomography (OCT) guided smart laser knife for cancer surgery (Conference Presentation)

    NASA Astrophysics Data System (ADS)

    Katta, Nitesh; Mcelroy, Austin; Estrada, Arnold; Milner, Thomas E.

    2017-02-01

    Neurological cancer surgeries require specialized tools that enhance imaging for precise cutting and removal of tissue without damaging adjacent neurological structures. The novel combination of high-resolution fast optical coherence tomography (OCT) alongside short pulsed nanosecond thulium (Tm) lasers offers stark advantages utilizing the superior beam quality, high volumetric tissue removal rates of thulium lasers with minimal residual thermal footprint in the tissue and avoiding damage to delicate sub-surface structures (e.g., nerves and microvessels); which has not been showcased before. A bench-top system is constructed, using a 15W 1940nm nanosecond pulsed Tm fiber laser (500uJ pulse energy, 100ns pulse duration, 30kHz repetition rate) for removing tissue and a swept source laser (1310±70nm, 100kHz sweep rate) is utilized for OCT imaging, forming a combined Tm/OCT system - a smart laser knife. The OCT image-guidance informs the Tm laser for cutting/removal of targeted tissue structures. Tissue phantoms were constructed to demonstrate surgical incision with blood vessel avoidance on the surface where 2mm wide 600um deep cuts are executed around the vessel using OCT to guide the procedure. Cutting up to delicate subsurface blood vessels (2mm deep) is demonstrated while avoiding damage to their walls. A tissue removal rate of 5mm^3/sec is obtained from the bench-top system. We constructed a blow-off model to characterize Tm cut depths taking into account the absorption coefficients and beam delivery systems to compute Arrhenius damage integrals. The model is used to compare predicted tissue removal rate and residual thermal injury with experimental values in response to Tm laser-tissue modification.

  19. Propagation d'impulsions femtosecondes térawatts dans l'atmosphère et applications

    NASA Astrophysics Data System (ADS)

    Méjean, G.

    2005-11-01

    Propagation of femtosecond terawatt laser in atmosphere and applications When ultrasshort and high-power laser pulses propagate across the atmosphere, self-guided filaments of 100 μm radius are formed. They result from a balance between Kerr self-focusing and defocusing by the plasma generated by multiphoton ionisation. During this work, we showed that the white light spectrum generated in filament spans from the infrared (4.5 μm) to the ultraviolet (230 nm) thanks to Third Harmonic Generation and self-phase modulation. We charaterized the propagation under different conditions (rain, smog, turbulence) to developp different atmospheric applications. In particular, we demostrated multi-parameters LIDAR for relative humidity as well as atmospheric pollution remote sensing. Furthermore, it is possible to detect and to identify biological aerosols or solid targets (LIBS) at remote distances, by non-linear processes induced in situ by the high intensity delivered by filaments. Moreover, we demonstrated that guiding and triggering high-voltage discharge thanks to a femsecond high-powered pulse is possible even under a rain with an efficiency comparable to that observed in dry air. We also impoved the efficiency of a two pulses configurations (a femtosecond pulse and a subsequent nanosecond pulse). These results raise hope that lightning could be triggered and guided by laser pulses in the future. Les impulsions laser ultra-brèves (fs) et ultra-intenses (TW) forment, au cours de leur propagation non-linéaire dans l'atmosphère, des structures auto-guidées, d'une centaine de microns de diamètre, appelées filaments. Ces filaments résultent d'un équilibre dynamique entre l'effet Kerr qui focalise le faisceau et la défocalisation due au plasma généré au sein de ceux-ci. Au cours des différentes études rapportées ici, nous avons mesuré que le spectre de lumière blanche issue de l'automodulation de phase et de la génération de troisième harmonique s'étend de l'ultraviolet (230 nm) à l'infrarouge (4,5 μm). De même, la propagation dans l'air, sous différentes conditions (pluie, brouillard, turbulence), des faisceaux térawatts femtosecondes a été caractérisée afin de développer des applications atmosphériques. Il nous a ainsi été possible de développer le LIDAR à lumière blanche pour réaliser des mesures préliminaires d'ozone et d'aérosols simultanément. De même, grâce à la propagation fortement non-linéaire du faisceau qui permet de transporter des hautes intensités sur de longue distance, nous avons pu détecter et identifier, à distance, des aérosols biologiques et des cibles solides (LIBS) en induisant in situ des effets non-linéaires. Enfin, nous avons montré que le déclenchement et le guidage de décharges de haute tension par une impulsion laser femtoseconde sous la pluie reste possible avec une efficacité comparable à l'atmosphère sèche. D'autre part, une configuration à double impulsion laser augmente l'efficacité de déclenchement des décharges. Ces résultats nous rapproche de la perspective de déclenchement et guidage de foudre par laser.

  20. Radiofrequency pulse design using nonlinear gradient magnetic fields.

    PubMed

    Kopanoglu, Emre; Constable, R Todd

    2015-09-01

    An iterative k-space trajectory and radiofrequency (RF) pulse design method is proposed for excitation using nonlinear gradient magnetic fields. The spatial encoding functions (SEFs) generated by nonlinear gradient fields are linearly dependent in Cartesian coordinates. Left uncorrected, this may lead to flip angle variations in excitation profiles. In the proposed method, SEFs (k-space samples) are selected using a matching pursuit algorithm, and the RF pulse is designed using a conjugate gradient algorithm. Three variants of the proposed approach are given: the full algorithm, a computationally cheaper version, and a third version for designing spoke-based trajectories. The method is demonstrated for various target excitation profiles using simulations and phantom experiments. The method is compared with other iterative (matching pursuit and conjugate gradient) and noniterative (coordinate-transformation and Jacobian-based) pulse design methods as well as uniform density spiral and EPI trajectories. The results show that the proposed method can increase excitation fidelity. An iterative method for designing k-space trajectories and RF pulses using nonlinear gradient fields is proposed. The method can either be used for selecting the SEFs individually to guide trajectory design, or can be adapted to design and optimize specific trajectories of interest. © 2014 Wiley Periodicals, Inc.

  1. Application of Plasma Waveguides to High Energy Accelerators

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Milchberg, Howard M

    2013-03-30

    The eventual success of laser-plasma based acceleration schemes for high-energy particle physics will require the focusing and stable guiding of short intense laser pulses in reproducible plasma channels. For this goal to be realized, many scientific issues need to be addressed. These issues include an understanding of the basic physics of, and an exploration of various schemes for, plasma channel formation. In addition, the coupling of intense laser pulses to these channels and the stable propagation of pulses in the channels require study. Finally, new theoretical and computational tools need to be developed to aid in the design and analysismore » of experiments and future accelerators. Here we propose a 3-year renewal of our combined theoretical and experimental program on the applications of plasma waveguides to high-energy accelerators. During the past grant period we have made a number of significant advances in the science of laser-plasma based acceleration. We pioneered the development of clustered gases as a new highly efficient medium for plasma channel formation. Our contributions here include theoretical and experimental studies of the physics of cluster ionization, heating, explosion, and channel formation. We have demonstrated for the first time the generation of and guiding in a corrugated plasma waveguide. The fine structure demonstrated in these guides is only possible with cluster jet heating by lasers. The corrugated guide is a slow wave structure operable at arbitrarily high laser intensities, allowing direct laser acceleration, a process we have explored in detail with simulations. The development of these guides opens the possibility of direct laser acceleration, a true miniature analogue of the SLAC RF-based accelerator. Our theoretical studies during this period have also contributed to the further development of the simulation codes, Wake and QuickPIC, which can be used for both laser driven and beam driven plasma based acceleration schemes. We will continue our development of advanced simulation tools by modifying the QuickPIC algorithm to allow for the simulation of plasma particle pick-up by the wake fields. We have also performed extensive simulations of plasma slow wave structures for efficient THz generation by guided laser beams or accelerated electron beams. We will pursue experimental studies of direct laser acceleration, and THz generation by two methods, ponderomotive-induced THz polarization, and THz radiation by laser accelerated electron beams. We also plan to study both conventional and corrugated plasma channels using our new 30 TW in our new lab facilities. We will investigate production of very long hydrogen plasma waveguides (5 cm). We will study guiding at increasing power levels through the onset of laser-induced cavitation (bubble regime) to assess the role played by the preformed channel. Experiments in direct acceleration will be performed, using laser plasma wakefields as the electron injector. Finally, we will use 2-colour ionization of gases as a high frequency THz source (<60 THz) in order for femtosecond measurements of low plasma densities in waveguides and beams.« less

  2. Telemetry with an Optical Fiber Revisited: An Alternative Strategy

    ERIC Educational Resources Information Center

    Kraftmakher, Yaakov

    2014-01-01

    With a new data-acquisition system developed by PASCO scientific, an experiment on telemetry with an optical fiber can be made easier and more accurate. For this aim, an alternative strategy of the remote temperature measurements is proposed: the frequency of light pulses transmitted via the light guide numerically equals the temperature using…

  3. System for testing optical fibers

    DOEpatents

    Davies, Terence J.; Franks, Larry A.; Nelson, Melvin A.

    1981-01-01

    A system for nondestructively determining the attenuation coefficient, .alpha.(.lambda.), of low-loss optical fiber wave guides. Cerenkov light pulses are generated at a plurality of locations in the fiber by a beam of charged particles. The transit times of selected spectral components and their intensities are utilized to unfold the .alpha.(.lambda.) values over the measured spectrum.

  4. Emissive color preferences and temporal alteration of walking performance by pulsing lights in colorado potato beetle

    USDA-ARS?s Scientific Manuscript database

    The Colorado potato beetle (CPB) Leptinotarsa decemlineata (Say 1824) is a diurnal insect that strongly relies on vision to guide its walk. In the present study, we investigated the orientation behavior of nondiapausing walking CPB in response to emissive colors produced by light emitting diodes (L...

  5. Quantitative Diagnostics of Multilayered Composite Structures with Ultrasonic Guided Waves

    DTIC Science & Technology

    2014-09-01

    sensors. These IDT sensors were fabricated from thin wafer of piezoelectric lead zirconate titanate ( PZT ) substrates by using a pulse laser micro...pavement structures," J. Acoust. Soc. Am., vol. 116, no. 5, pp. 2902-2913, 2004. [9] E. Kostson and P. Fromme, " Fatigue crack growth monitoring in multi

  6. Highly coherent mid-IR supercontinuum by self-defocusing solitons in lithium niobate waveguides with all-normal dispersion.

    PubMed

    Guo, Hairun; Zhou, Binbin; Zeng, Xianglong; Bache, Morten

    2014-05-19

    We numerically investigate self-defocusing solitons in a lithium niobate (LN) waveguide designed to have a large refractive index (RI) change. The waveguide evokes strong waveguide dispersion and all-normal dispersion is found in the entire guiding band spanning the near-IR and the beginning of the mid-IR. Meanwhile, a self-defocusing nonlinearity is invoked by the cascaded (phase-mismatched) second-harmonic generation under a quasi-phase-matching pitch. Combining this with the all-normal dispersion, mid-IR solitons can form and the waveguide presents the first all-nonlinear and solitonic device where no linear dispersion (i.e. non-solitonic) regimes exist within the guiding band. Soliton compressions at 2 μm and 3 μm are investigated, with nano-joule single cycle pulse formations and highly coherent octave-spanning supercontinuum generations. With an alternative design on the waveguide dispersion, the soliton spectral tunneling effect is also investigated, with which few-cycle pico-joule pulses at 2 μm are formed by a near-IR pump.

  7. TH-F-202-03: Advances in MRI for Radiation Therapy

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cai, J.

    MRI has excellent soft tissue contrast and can provide both anatomical and physiological information. It is becoming increasingly important in radiation therapy for treatment planning, image-guided radiation therapy, and treatment assessment. It is critically important at this time point to educate and update our medical physicists about MRI to prepare for the upcoming surge of MRI applications in radiation therapy. This session will review important basics of MR physics, pulse sequence designs, and current radiotherapy application, as well as showcase exciting new developments in MRI that can be potentially useful in radiation therapy. Learning Objectives: To learn basics of MRmore » physics and understand the differences between various pulse sequences To review current applications of MRI in radiation therapy.To discuss recent MRI advances for future MRI guided radiation therapy Partly supported by NIH (1R21CA165384).; W. Miller, Research supported in part by Siemens Healthcare; G. Li, My clinical research is in part supported by NIH U54CA137788. I have a collaborative research project with Philips Healthcare.; J. Cai, jing cai.« less

  8. TH-F-202-00: MRI for Radiation Therapy

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    MRI has excellent soft tissue contrast and can provide both anatomical and physiological information. It is becoming increasingly important in radiation therapy for treatment planning, image-guided radiation therapy, and treatment assessment. It is critically important at this time point to educate and update our medical physicists about MRI to prepare for the upcoming surge of MRI applications in radiation therapy. This session will review important basics of MR physics, pulse sequence designs, and current radiotherapy application, as well as showcase exciting new developments in MRI that can be potentially useful in radiation therapy. Learning Objectives: To learn basics of MRmore » physics and understand the differences between various pulse sequences To review current applications of MRI in radiation therapy.To discuss recent MRI advances for future MRI guided radiation therapy Partly supported by NIH (1R21CA165384).; W. Miller, Research supported in part by Siemens Healthcare; G. Li, My clinical research is in part supported by NIH U54CA137788. I have a collaborative research project with Philips Healthcare.; J. Cai, jing cai.« less

  9. TH-F-202-01: MRI Basics

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Miller, W.

    MRI has excellent soft tissue contrast and can provide both anatomical and physiological information. It is becoming increasingly important in radiation therapy for treatment planning, image-guided radiation therapy, and treatment assessment. It is critically important at this time point to educate and update our medical physicists about MRI to prepare for the upcoming surge of MRI applications in radiation therapy. This session will review important basics of MR physics, pulse sequence designs, and current radiotherapy application, as well as showcase exciting new developments in MRI that can be potentially useful in radiation therapy. Learning Objectives: To learn basics of MRmore » physics and understand the differences between various pulse sequences To review current applications of MRI in radiation therapy.To discuss recent MRI advances for future MRI guided radiation therapy Partly supported by NIH (1R21CA165384).; W. Miller, Research supported in part by Siemens Healthcare; G. Li, My clinical research is in part supported by NIH U54CA137788. I have a collaborative research project with Philips Healthcare.; J. Cai, jing cai.« less

  10. TH-F-202-02: Current Applications of MRI in Radiotherapy

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Li, G.

    MRI has excellent soft tissue contrast and can provide both anatomical and physiological information. It is becoming increasingly important in radiation therapy for treatment planning, image-guided radiation therapy, and treatment assessment. It is critically important at this time point to educate and update our medical physicists about MRI to prepare for the upcoming surge of MRI applications in radiation therapy. This session will review important basics of MR physics, pulse sequence designs, and current radiotherapy application, as well as showcase exciting new developments in MRI that can be potentially useful in radiation therapy. Learning Objectives: To learn basics of MRmore » physics and understand the differences between various pulse sequences To review current applications of MRI in radiation therapy.To discuss recent MRI advances for future MRI guided radiation therapy Partly supported by NIH (1R21CA165384).; W. Miller, Research supported in part by Siemens Healthcare; G. Li, My clinical research is in part supported by NIH U54CA137788. I have a collaborative research project with Philips Healthcare.; J. Cai, jing cai.« less

  11. GigaGauss solenoidal magnetic field inside bubbles excited in under-dense plasma

    PubMed Central

    Lécz, Zs.; Konoplev, I. V.; Seryi, A.; Andreev, A.

    2016-01-01

    This paper proposes a novel and effective method for generating GigaGauss level, solenoidal quasi-static magnetic fields in under-dense plasma using screw-shaped high intensity laser pulses. This method produces large solenoidal fields that move with the driving laser pulse and are collinear with the accelerated electrons. This is in contrast with already known techniques which rely on interactions with over-dense or solid targets and generates radial or toroidal magnetic field localized at the stationary target. The solenoidal field is quasi-stationary in the reference frame of the laser pulse and can be used for guiding electron beams. It can also provide synchrotron radiation beam emittance cooling for laser-plasma accelerated electron and positron beams, opening up novel opportunities for designs of the light sources, free electron lasers, and high energy colliders based on laser plasma acceleration. PMID:27796327

  12. GigaGauss solenoidal magnetic field inside bubbles excited in under-dense plasma

    NASA Astrophysics Data System (ADS)

    Lécz, Zs.; Konoplev, I. V.; Seryi, A.; Andreev, A.

    2016-10-01

    This paper proposes a novel and effective method for generating GigaGauss level, solenoidal quasi-static magnetic fields in under-dense plasma using screw-shaped high intensity laser pulses. This method produces large solenoidal fields that move with the driving laser pulse and are collinear with the accelerated electrons. This is in contrast with already known techniques which rely on interactions with over-dense or solid targets and generates radial or toroidal magnetic field localized at the stationary target. The solenoidal field is quasi-stationary in the reference frame of the laser pulse and can be used for guiding electron beams. It can also provide synchrotron radiation beam emittance cooling for laser-plasma accelerated electron and positron beams, opening up novel opportunities for designs of the light sources, free electron lasers, and high energy colliders based on laser plasma acceleration.

  13. Orthogonal on-off control of radar pulses for the suppression of mutual interference

    NASA Astrophysics Data System (ADS)

    Kim, Yong Cheol

    1998-10-01

    Intelligent vehicles of the future will be guided by radars and other sensors to avoid obstacles. When multiple vehicles move simultaneously in autonomous navigational mode, mutual interference among car radars becomes a serious problem. An obstacle is illuminated with electromagnetic pulses from several radars. The signal at a radar receiver is actually a mixture of the self-reflection and the reflection of interfering pulses emitted by others. When standardized pulse- type radars are employed on vehicles for obstacle avoidance and so self-pulse and interfering pulses have identical pulse repetition interval, this SI (synchronous Interference) is very difficult to separate from the true reflection. We present a method of suppressing such a synchronous interference. By controlling the pulse emission of a radar in a binary orthogonal ON, OFF pattern, the true self-reflection can be separated from the false one. Two range maps are generated, TRM (true-reflection map) and SIM (synchronous- interference map). TRM is updated for every ON interval and SIM is updated for every OFF interval of the self-radar. SIM represents the SI of interfering radars while TRM keeps a record of a mixture of the true self-reflection and SI. Hence the true obstacles can be identified by the set subtraction operation. The performance of the proposed method is compared with that of the conventional M of N method. Bayesian analysis shows that the probability of false alarm is improved by order of 103 to approximately 106 while the deterioration in the probability of detection is negligible.

  14. A novel fiber laser development for photoacoustic microscopy

    NASA Astrophysics Data System (ADS)

    Yavas, Seydi; Aytac-Kipergil, Esra; Arabul, Mustafa U.; Erkol, Hakan; Akcaalan, Onder; Eldeniz, Y. Burak; Ilday, F. Omer; Unlu, Mehmet B.

    2013-03-01

    Photoacoustic microscopy, as an imaging modality, has shown promising results in imaging angiogenesis and cutaneous malignancies like melanoma, revealing systemic diseases including diabetes, hypertension, tracing drug efficiency and assessment of therapy, monitoring healing processes such as wound cicatrization, brain imaging and mapping. Clinically, photoacoustic microscopy is emerging as a capable diagnostic tool. Parameters of lasers used in photoacoustic microscopy, particularly, pulse duration, energy, pulse repetition frequency, and pulse-to-pulse stability affect signal amplitude and quality, data acquisition speed and indirectly, spatial resolution. Lasers used in photoacoustic microscopy are typically Q-switched lasers, low-power laser diodes, and recently, fiber lasers. Significantly, the key parameters cannot be adjusted independently of each other, whereas microvasculature and cellular imaging, e.g., have different requirements. Here, we report an integrated fiber laser system producing nanosecond pulses, covering the spectrum from 600 nm to 1100 nm, developed specifically for photoacoustic excitation. The system comprises of Yb-doped fiber oscillator and amplifier, an acousto-optic modulator and a photonic-crystal fiber to generate supercontinuum. Complete control over the pulse train, including generation of non-uniform pulse trains, is achieved via the AOM through custom-developed field-programmable gate-array electronics. The system is unique in that all the important parameters are adjustable: pulse duration in the range of 1-3 ns, pulse energy up to 10 μJ, repetition rate from 50 kHz to 3 MHz. Different photocoustic imaging probes can be excited with the ultrabroad spectrum. The entire system is fiber-integrated; guided-beam-propagation rendersit misalignment free and largely immune to mechanical perturbations. The laser is robust, low-cost and built using readily available components.

  15. Laser positioning of four-quadrant detector based on pseudo-random sequence

    NASA Astrophysics Data System (ADS)

    Tang, Yanqin; Cao, Ercong; Hu, Xiaobo; Gu, Guohua; Qian, Weixian

    2016-10-01

    Nowadays the technology of laser positioning based on four-quadrant detector has the wide scope of the study and application areas. The main principle of laser positioning is that by capturing the projection of the laser spot on the photosensitive surface of the detector, and then calculating the output signal from the detector to obtain the coordinates of the spot on the photosensitive surface of the detector, the coordinate information of the laser spot in the space with respect to detector system which reflects the spatial position of the target object is calculated effectively. Given the extensive application of FPGA technology and the pseudo-random sequence has the similar correlation of white noise, the measurement process of the interference, noise has little effect on the correlation peak. In order to improve anti-jamming capability of the guided missile in tracking process, when the laser pulse emission, the laser pulse period is pseudo-random encoded which maintains in the range of 40ms-65ms so that people of interfering can't find the exact real laser pulse. Also, because the receiver knows the way to solve the pseudo-random code, when the receiver receives two consecutive laser pulses, the laser pulse period can be decoded successfully. In the FPGA hardware implementation process, around each laser pulse arrival time, the receiver can open a wave door to get location information contained the true signal. Taking into account the first two consecutive pulses received have been disturbed, so after receiving the first laser pulse, it receives all the laser pulse in the next 40ms-65ms to obtain the corresponding pseudo-random code.

  16. Plasma Channel Lenses and Plasma Tornadoes for Optical Beam Focusing and Transport

    NASA Astrophysics Data System (ADS)

    Hubbard, R. F.; Kaganovich, D.; Johnson, L. A.; Gordon, D. F.; Penano, J. R.; Hafizi, B.; Helle, M. H.; Mamonau, A. A.

    2017-10-01

    Shaped plasmas offer the possibility of manipulating laser pulses at intensities far above the damage limits for conventional optics. An example is the plasma channel, which is a cylindrical plasma column with an on-axis density minimum. Long plasma channels have been widely used to guide intense laser pulses, particularly in laser wakefield accelerators. A new concept, the ``plasma tornado'', offers the possibility of creating long plasma channels with no nearby structures and at densities lower than can be achieved by capillary discharges. A short plasma channel can focus a laser pulse in much the same manner as a conventional lens or off-axis parabola. When placed in front of the focal point of an intense laser pulse, a plasma channel lens (PCL) can reduce the effective f-number of conventional focusing optics. When placed beyond the focal point, it can act as a collimator. We will present experimental and modeling results for a new plasma tornado design, review experimental methods for generating short PCLs, and discuss potential applications. Supported by the Naval Research Laboratory Base Program.

  17. Delivery of high energy Er:YAG pulsed laser light at 2.94 µm through a silica hollow core photonic crystal fibre.

    PubMed

    Urich, A; Maier, R R J; Mangan, B J; Renshaw, S; Knight, J C; Hand, D P; Shephard, J D

    2012-03-12

    In this paper the delivery of high power Er:YAG laser pulses through a silica hollow core photonic crystal fibre is demonstrated. The Er:YAG wavelength of 2.94 µm is well beyond the normal transmittance of bulk silica but the unique hollow core guidance allows silica to guide in this regime. We have demonstrated for the first time the ability to deliver high energy pulses through an all-silica fibre at 2.94 µm. These silica fibres are mechanically and chemically robust, biocompatible and have low sensitivity to bending. A maximum pulse energy of 14 mJ at 2.94 µm was delivered through the fibre. This, to our knowledge, is the first time a silica hollow core photonic crystal fibre has been shown to transmit 2.94 μm laser light at a fluence exceeding the thresholds required for modification (e.g. cutting and drilling) of hard biological tissue. Consequently, laser delivery systems based on these fibres have the potential for the realization of novel, minimally-invasive surgical procedures.

  18. Discourse on pulse in medieval Persia--the Hidayat of Al-Akhawayni (?-983 A D.).

    PubMed

    Khodadoust, Kazem; Ardalan, Mohammadreza; Ghabili, Kamyar; Golzari, Samad E J; Eknoyan, Garabed

    2013-06-20

    In a period of compilation, original observations and expansion (900-1100 A.D.), Persians described new clinical manifestations of the diseases and expanded the earlier knowledge of materia medica. In the epoch of the Arabic language domination in the scientific literature of this period, advent of medical authors to write in Farsi shined in the Persian principalities. Akhawayani Bokhari was by far the most outstanding scholar of the time who wrote one of the earliest pandects of medicine of the period, the Hidayat al-Mutallimin fi al-Tibb (Learner's Guide to Medicine) in new Persian. The Hidayat is a relatively short and simplified digest of medicine at the time providing a glimpse of high level of medical education at the Samanid period (819-999). The present article is a translation of the sections of the Hidayat related to the pulse and its characters and conditions affecting the pulse in an attempt to increase our knowledge of the medicine, and particularly the pulse examination throughout the medieval era. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

  19. Comparison between ultrasound-guided interfascial pulsed radiofrequency and ultrasound-guided interfascial block with local anesthetic in myofascial pain syndrome of trapezius muscle

    PubMed Central

    Cho, Ik Tae; Cho, Yun Woo; Kwak, Sang Gyu; Chang, Min Cheol

    2017-01-01

    Abstract Myofascial pain syndrome (MPS) of the trapezius muscle (TM) is a frequently occurring musculoskeletal disorder. However, the treatment of MPS of the TM remains a challenge. We investigated the effects of ultrasound (US)-guided pulsed radiofrequency (PRF) stimulation on the interfascial area of the TM. In addition, we compared its effect with that of interfascial block (IFB) with 10 mL of 0.6% lidocaine on the interfascial area of the TM. Thirty-six patients with MPS of the TM were included and randomly assigned into 2 groups. Eighteen patients underwent PRF stimulation on the interfascial area of the TM (PRF group) and 18 patients underwent IFB with lidocaine on the same area (IFB group). Pain intensity was evaluated using a numerical rating scale (NRS) at pretreatment, 2, 4, and 8 weeks after treatment. At pretreatment and 8 weeks after treatment, quality of life was assessed using the Short Form-36 Health Survey (SF-36), which includes the physical component score (PCS) and the mental component score (MCS). One patient in the PRF group was lost to follow-up. Patients in both groups showed a significant decrease in NRS scores at 2, 4, and 8 weeks after treatments and a significant increase in PCS and MCS of the SF-36 at 8 weeks after treatments. Two weeks after each treatment, the decrements of NRS scores were not significantly different between the 2 groups. However, 4 and 8 weeks after the procedures, we found that the NRS score was significantly lower in the PRF group than in the IFB group. At 8 weeks after the treatments, PCS and MCS of the SF-36 in the PRF group were significantly higher than those in the IFB group. For the management of MPS of the TM, US-guided interfascial PRF had a better long-term effect on reducing the pain and the quality of life compared to US-guided IFB. Therefore, we think US-guided PRF stimulation on the interfascial area of the TM can be a beneficial alternative to manage the pain following MPS of the TM. PMID:28151904

  20. Comparison between ultrasound-guided interfascial pulsed radiofrequency and ultrasound-guided interfascial block with local anesthetic in myofascial pain syndrome of trapezius muscle.

    PubMed

    Cho, Ik Tae; Cho, Yun Woo; Kwak, Sang Gyu; Chang, Min Cheol

    2017-02-01

    Myofascial pain syndrome (MPS) of the trapezius muscle (TM) is a frequently occurring musculoskeletal disorder. However, the treatment of MPS of the TM remains a challenge. We investigated the effects of ultrasound (US)-guided pulsed radiofrequency (PRF) stimulation on the interfascial area of the TM. In addition, we compared its effect with that of interfascial block (IFB) with 10 mL of 0.6% lidocaine on the interfascial area of the TM. Thirty-six patients with MPS of the TM were included and randomly assigned into 2 groups. Eighteen patients underwent PRF stimulation on the interfascial area of the TM (PRF group) and 18 patients underwent IFB with lidocaine on the same area (IFB group). Pain intensity was evaluated using a numerical rating scale (NRS) at pretreatment, 2, 4, and 8 weeks after treatment. At pretreatment and 8 weeks after treatment, quality of life was assessed using the Short Form-36 Health Survey (SF-36), which includes the physical component score (PCS) and the mental component score (MCS). One patient in the PRF group was lost to follow-up. Patients in both groups showed a significant decrease in NRS scores at 2, 4, and 8 weeks after treatments and a significant increase in PCS and MCS of the SF-36 at 8 weeks after treatments. Two weeks after each treatment, the decrements of NRS scores were not significantly different between the 2 groups. However, 4 and 8 weeks after the procedures, we found that the NRS score was significantly lower in the PRF group than in the IFB group. At 8 weeks after the treatments, PCS and MCS of the SF-36 in the PRF group were significantly higher than those in the IFB group. For the management of MPS of the TM, US-guided interfascial PRF had a better long-term effect on reducing the pain and the quality of life compared to US-guided IFB. Therefore, we think US-guided PRF stimulation on the interfascial area of the TM can be a beneficial alternative to manage the pain following MPS of the TM.

  1. Vaporization and recondensation dynamics of indocyanine green-loaded perfluoropentane droplets irradiated by a short pulse laser

    NASA Astrophysics Data System (ADS)

    Yu, Jaesok; Chen, Xucai; Villanueva, Flordeliza S.; Kim, Kang

    2016-12-01

    Phase-transition droplets have been proposed as promising contrast agents for ultrasound and photoacoustic imaging. Short pulse laser activated perfluorocarbon-based droplets, especially when in a medium with a temperature below their boiling point, undergo phase changes of vaporization and recondensation in response to pulsed laser irradiation. Here, we report and discuss the vaporization and recondensation dynamics of perfluoropentane droplets containing indocyanine green in response to a short pulsed laser with optical and acoustic measurements. To investigate the effect of temperature on the vaporization process, an imaging chamber was mounted on a temperature-controlled water reservoir and then the vaporization event was recorded at 5 million frames per second via a high-speed camera. The high-speed movies show that most of the droplets within the laser beam area expanded rapidly as soon as they were exposed to the laser pulse and immediately recondensed within 1-2 μs. The vaporization/recondensation process was consistently reproduced in six consecutive laser pulses to the same area. As the temperature of the media was increased above the boiling point of the perfluoropentane, the droplets were less likely to recondense and remained in a gas phase after the first vaporization. These observations will help to clarify the underlying processes and eventually guide the design of repeatable phase-transition droplets as a photoacoustic imaging contrast agent.

  2. The Sterilization Effect of Cooperative Treatment of High Voltage Electrostatic Field and Variable Frequency Pulsed Electromagnetic Field on Heterotrophic Bacteria in Circulating Cooling Water

    NASA Astrophysics Data System (ADS)

    Gao, Xuetong; Liu, Zhian; Zhao, Judong

    2018-01-01

    Compared to other treatment of industrial circulating cooling water in the field of industrial water treatment, high-voltage electrostatic field and variable frequency pulsed electromagnetic field co-sterilization technology, an advanced technology, is widely used because of its special characteristics--low energy consumption, nonpoisonous and environmentally friendly. In order to get a better cooling water sterilization effect under the premise of not polluting the environment, some experiments about sterilization of heterotrophic bacteria in industrial circulating cooling water by cooperative treatment of high voltage electrostatic field and variable frequency pulsed electromagnetic field were carried out. The comparison experiment on the sterilization effect of high-voltage electrostatic field and variable frequency pulsed electromagnetic field co-sterilization on heterotrophic bacteria in industrial circulating cooling water was carried out by change electric field strength and pulse frequency. The results show that the bactericidal rate is selective to the frequency and output voltage, and the heterotrophic bacterium can only kill under the condition of sweep frequency range and output voltage. When the voltage of the high voltage power supply is 4000V, the pulse frequency is 1000Hz and the water temperature is 30°C, the sterilization rate is 48.7%, the sterilization rate is over 90%. Results of this study have important guiding significance for future application of magnetic field sterilization.

  3. Pulsed radiofrequency on radial nerve under ultrasound guidance for treatment of intractable lateral epicondylitis.

    PubMed

    Oh, Dae Seok; Kang, Tae Hyung; Kim, Hyae Jin

    2016-06-01

    Lateral epicondylitis is a painful and functionally limiting disorder. Although lateral elbow pain is generally self-limiting, in a minority of people symptoms persist for a long time. When various conservative treatments fail, surgical approach is recommended. Surgical denervation of several nerves that innervate the lateral humeral epicondyle could be considered in patients with refractory pain because it denervates the region of pain. Pulsed radiofrequency is a minimally invasive procedure that improves chronic pain when applied to various neural tissues without causing any significant destruction and painful complication. This procedure is safe, minimally invasive, and has less risk of complications relatively compared to the surgical approach. The radial nerve can be identified as a target for pulsed radiofrequency lesioning in lateral epicondylitis. This innovative method of pulsed radiofrequency applied to the radial nerve has not been reported before. We reported on two patients with intractable lateral epicondylitis suffering from elbow pain who did not respond to nonoperative treatments, but in whom the ultrasound-guided pulsed radiofrequency neuromodulation of the radial nerve induced symptom improvement. After a successful diagnostic nerve block, radiofrequency probe adjustment around the radial nerve was performed on the lateral aspect of the distal upper arm under ultrasound guidance and multiple pulsed treatments were applied. A significant reduction in pain was reported over the follow-up period of 12 weeks.

  4. Neutron optics concept for the materials engineering diffractometer at the ESS

    NASA Astrophysics Data System (ADS)

    Šaroun, J.; Fenske, J.; Rouijaa, M.; Beran, P.; Navrátil, J.; Lukáš, P.; Schreyer, A.; Strobl, M.

    2016-09-01

    The Beamline for European Materials Engineering Research (BEER) has been recently proposed to be built at the European Spallation Source (ESS). The presented concept of neutron delivery optics for this instrument addresses the problems of bi-spectral beam extraction from a small moderator, optimization of neutron guides profile for long-range neutron transport and focusing at the sample under various constraints. They include free space before and after the guides, a narrow guide section with gaps for choppers, closing of direct line of sight and cost reduction by optimization of the guides cross-section and coating. A system of slits and exchangeable focusing optics is proposed in order to match various wavelength resolution options provided by the pulse shaping and modulation choppers, which permits to efficiently trade resolution for intensity in a wide range. Simulated performance characteristics such as brilliance transfer ratio are complemented by the analysis of the histories of “useful” neutrons obtained by back tracing neutrons hitting the sample, which helps to optimize some of the neutron guide parameters such as supermirror coating.

  5. A detailed examination of the LWFA in the Self-Guided Nonlinear Blowout Regime for 15-100 Joule Lasers

    NASA Astrophysics Data System (ADS)

    Davidson, Asher; Tableman, Adam; Yu, Peicheng; An, Weiming; Tsung, Frank; Mori, Warren; Lu, Wei; Fonseca, Ricardo

    2017-10-01

    We examine scaling laws for LWFA in the regime nonlinear, self-guided regime in detail using the quasi-3D version of the particle-in-cell code OSIRIS. We find that the scaling laws continue to work well when we fix the normalized laser amplitude while reducing plasma density. It is further found that the energy gain for fixed laser energy can be improved by shortening the pulse length until self-guiding almost no longer occurs and that the energy gain can be optimized by using lasers with asymmetric longitudinal profiles. We find that when optimized, a 15 J laser may yield particle energies as high as 5.3 GeV without the need of any external guiding. Detailed studies for optimizing energy gains from 30 J and 100 J lasers will also presented which indicate that energies in excess of 10 GeV can be possible in the near term without the need for external guiding. This work is supported by the NSF and DOE.

  6. Classical and low-light-level detection and pulse characterization using optical-frequency mixers

    NASA Astrophysics Data System (ADS)

    Langrock, Carsten

    2007-12-01

    Classical all-optical signal processing for telecommunication applications greatly benefits from the availability of highly efficient optical frequency (OF) mixers, the optical analogue of radio-frequency mixers used in RF signal processing. The OF mixers presented in this dissertation are based on reverse-proton-exchange (RPE) periodically-poled lithium niobate (PPLN) waveguides, one of the most efficient and versatile material systems in the field of nonlinear optics to date. Taking advantage of fabrication technologies developed in Prof. Martin Fejer's group over the past two decades, we expand the range of applications for these OF mixers to low-light-level signal detection and pulse characterization. We demonstrate high-speed high-efficiency single-photon counting at telecommunication wavelengths, used for the implementation of record-breaking quantum-key distribution systems, which allow unconditionally secure data transfer. In collaboration with researchers at the MIT Lincoln Laboratory, we also show that the very same technology can be used to achieve an order of magnitude improvement in the sensitivity of classical few-photon free-space communication links based on pulse-position modulation. These extremely sensitive receivers (1 photon/bit) are being developed to facilitate deep-space communication over several hundred million kilometers between Mars and Earth. OF mixers can also be used to fully characterize, potentially weak, ultrashort pulses, as well as time-magnify segments of ultra-high-speed data streams to be detected in real time by conventional streak cameras and oscilloscopes. We will present a novel implementation of both collinear autocorrelation as well as parametric temporal imaging (in collaboration with the Lawrence Livermore National Laboratory) based on mode-multiplexing in integrated asymmetric Y-junctions in combination with linearly-chirped apodized quasi-phasematching gratings. For the first time, background-free autocorrelation, frequency-resolved optical gating, and temporal imaging can be realized in single-polarization-guiding collinear waveguide structures at sub-60-aJ (400 photons/pulse) levels. Recently, guided-wave OF mixers have also become important for precision metrology applications based on frequency-comb generation (FCG) (i.e. optical ruler) using ultrashort pulses. The most compact and energy efficient FCG systems use fiber lasers. In collaboration with IMRA America, Inc., we demonstrate that RPE PPLN waveguides can be used to implement fully integrated fiber-laser-based FCG systems taking advantage of unprecedented octave-spanning spectral broadening of the input pulses in combination with simultaneous phase sensing inside the same waveguide.

  7. Respiratory motion management using audio-visual biofeedback for respiratory-gated radiotherapy of synchrotron-based pulsed heavy-ion beam delivery

    PubMed Central

    He, Pengbo; Li, Qiang; Liu, Xinguo; Dai, Zhongying; Zhao, Ting; Fu, Tingyan; Shen, Guosheng; Ma, Yuanyuan; Huang, Qiyan; Yan, Yuanlin

    2014-01-01

    Purpose: To efficiently deliver respiratory-gated radiation during synchrotron-based pulsed heavy-ion radiotherapy, a novel respiratory guidance method combining a personalized audio-visual biofeedback (BFB) system, breath hold (BH), and synchrotron-based gating was designed to help patients synchronize their respiratory patterns with synchrotron pulses and to overcome typical limitations such as low efficiency, residual motion, and discomfort. Methods: In-house software was developed to acquire body surface marker positions and display BFB, gating signals, and real-time beam profiles on a LED screen. Patients were prompted to perform short BHs or short deep breath holds (SDBH) with the aid of BFB following a personalized standard BH/SDBH (stBH/stSDBH) guiding curve or their own representative BH/SDBH (reBH/reSDBH) guiding curve. A practical simulation was performed for a group of 15 volunteers to evaluate the feasibility and effectiveness of this method. Effective dose rates (EDRs), mean absolute errors between the guiding curves and the measured curves, and mean absolute deviations of the measured curves were obtained within 10%–50% duty cycles (DCs) that were synchronized with the synchrotron’s flat-top phase. Results: All maneuvers for an individual volunteer took approximately half an hour, and no one experienced discomfort during the maneuvers. Using the respiratory guidance methods, the magnitude of residual motion was almost ten times less than during nongated irradiation, and increases in the average effective dose rate by factors of 2.39–4.65, 2.39–4.59, 1.73–3.50, and 1.73–3.55 for the stBH, reBH, stSDBH, and reSDBH guiding maneuvers, respectively, were observed in contrast with conventional free breathing-based gated irradiation, depending on the respiratory-gated duty cycle settings. Conclusions: The proposed respiratory guidance method with personalized BFB was confirmed to be feasible in a group of volunteers. Increased effective dose rate and improved overall treatment precision were observed compared to conventional free breathing-based, respiratory-gated irradiation. Because breathing guidance curves could be established based on the respective average respiratory period and amplitude for each patient, it may be easier for patients to cooperate using this technique. PMID:25370622

  8. Respiratory motion management using audio-visual biofeedback for respiratory-gated radiotherapy of synchrotron-based pulsed heavy-ion beam delivery

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    He, Pengbo; Ma, Yuanyuan; Huang, Qiyan

    Purpose: To efficiently deliver respiratory-gated radiation during synchrotron-based pulsed heavy-ion radiotherapy, a novel respiratory guidance method combining a personalized audio-visual biofeedback (BFB) system, breath hold (BH), and synchrotron-based gating was designed to help patients synchronize their respiratory patterns with synchrotron pulses and to overcome typical limitations such as low efficiency, residual motion, and discomfort. Methods: In-house software was developed to acquire body surface marker positions and display BFB, gating signals, and real-time beam profiles on a LED screen. Patients were prompted to perform short BHs or short deep breath holds (SDBH) with the aid of BFB following a personalized standardmore » BH/SDBH (stBH/stSDBH) guiding curve or their own representative BH/SDBH (reBH/reSDBH) guiding curve. A practical simulation was performed for a group of 15 volunteers to evaluate the feasibility and effectiveness of this method. Effective dose rates (EDRs), mean absolute errors between the guiding curves and the measured curves, and mean absolute deviations of the measured curves were obtained within 10%–50% duty cycles (DCs) that were synchronized with the synchrotron’s flat-top phase. Results: All maneuvers for an individual volunteer took approximately half an hour, and no one experienced discomfort during the maneuvers. Using the respiratory guidance methods, the magnitude of residual motion was almost ten times less than during nongated irradiation, and increases in the average effective dose rate by factors of 2.39–4.65, 2.39–4.59, 1.73–3.50, and 1.73–3.55 for the stBH, reBH, stSDBH, and reSDBH guiding maneuvers, respectively, were observed in contrast with conventional free breathing-based gated irradiation, depending on the respiratory-gated duty cycle settings. Conclusions: The proposed respiratory guidance method with personalized BFB was confirmed to be feasible in a group of volunteers. Increased effective dose rate and improved overall treatment precision were observed compared to conventional free breathing-based, respiratory-gated irradiation. Because breathing guidance curves could be established based on the respective average respiratory period and amplitude for each patient, it may be easier for patients to cooperate using this technique.« less

  9. Impact of MR-guided boiling histotripsy in distinct murine tumor models.

    PubMed

    Hoogenboom, Martijn; Eikelenboom, Dylan C; van den Bijgaart, Renske J E; Heerschap, Arend; Wesseling, Pieter; den Brok, Martijn H; Fütterer, Jurgen J; Adema, Gosse J

    2017-09-01

    Interest in mechanical high intensity focused ultrasound (HIFU) ablation is rapidly growing. Boiling histotripsy (BH) is applied for mechanical fragmentation of soft tissue into submicron fragments with limited temperature increase using the shock wave and cavitation effects of HIFU. Research on BH has been largely limited to ex vivo experiments. As a consequence, the in vivo pathology after BH treatment and the relation to preexistent tissue characteristics are not well understood. This study reports on in vivo MR guided BH treatment, either with 100 or 200 pulses per focal spot, in three different subcutaneous mouse tumor models: a soft-tissue melanoma (B16OVA), a compact growing thymoma (EL4), and a highly vascularized neuroblastoma (9464D). Extensive treatment evaluation was performed using MR imaging followed by histopathology 2h after treatment. T2 weighted MRI allowed direct in vivo visualization of the BH lesions in all tumor models. The 100-pulse treated area in the B16OVA tumors was larger than the predicted treatment volume (500±10%). For the more compact growing EL4 and 9464D tumors this was 95±13% and 55±33%, respectively. Histopathology after the 100-pulse treatment revealed completely disintegrated lesions in the treated area with sharp borders in the compact EL4 and 9464D tumors, while for B16OVA tumors the lesion contained a mixture of discohesive (partly viable) clusters of cells, micro-vessel remainings, and tumor cell debris. The treatment of B16OVA with 200 pulses increased the fragmentation of tumor tissue. In all tumor types only micro-hemorrhages were detected after ablation (slightly higher after 200-pulse treatment for the highly vascularized 9464D tumors). Collagen staining revealed that the collagen fibers were to a greater or lesser extent still intact and partly clotted together near the lesion border in all tumor models. In conclusion, this study reveals effective mechanical fragmentation of different tumor types using BH without major hemorrhages. However, treatment settings may need to be adjusted to the tissue characteristics for optimal tissue fragmentation. Copyright © 2017 Elsevier B.V. All rights reserved.

  10. Acoustic Guided Wave Testing of Pipes of Small Diameters

    NASA Astrophysics Data System (ADS)

    Muravev, V. V.; Muraveva, O. V.; Strizhak, V. A.; Myshkin, Y. V.

    2017-10-01

    Acoustic path is analyzed and main parameters of guided wave testing are substanti- ated applied to pipes of small diameters. The method is implemented using longitudinal L(0,1) and torsional T(0,1) waves based on electromagnetic-acoustic (EMA) transducers. The method of multiple reflections (MMR) combines echo-through, amplitude-shadow and time-shadow methods. Due to the effect of coherent amplification of echo-pulses from defects the sensitivity to the defects of small sizes at the signal analysis on the far reflections is increased. An oppor- tunity of detection of both local defects (dents, corrosion damages, rolling features, pitting, cracks) and defects extended along the pipe is shown.

  11. Theory and Simulation of Gain-Guided Noncollinear Modes in Chirped Quasi-Phase-Matched Optical Parametric Amplifiers

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Charbonneau-Lefort, Mathieu; Afeyan, Bedros; Fejer, Martin

    Chirped quasi-phase-matched (QPM) gratings offer essentially constant gain over wide bandwidths, making them promising candidates for short-pulse optical parametric amplifiers. However, experiments have shown that high-gain non-collinear processes exist in spite of the dephasing caused by the non-uniformity of the QPM grating and compete with the desired collinear broadband gain of the amplifier. In this paper, these non-collinear gain-guided modes are investigated numerically and analytically in a model that includes longitudinal non-uniformity of the phase-matching profile, lateral localization of the pump beam and non-collinear propagation of the interacting waves.

  12. Superradiance for Atoms Trapped along a Photonic Crystal Waveguide

    NASA Astrophysics Data System (ADS)

    Goban, A.; Hung, C.-L.; Hood, J. D.; Yu, S.-P.; Muniz, J. A.; Painter, O.; Kimble, H. J.

    2015-08-01

    We report observations of superradiance for atoms trapped in the near field of a photonic crystal waveguide (PCW). By fabricating the PCW with a band edge near the D1 transition of atomic cesium, strong interaction is achieved between trapped atoms and guided-mode photons. Following short-pulse excitation, we record the decay of guided-mode emission and find a superradiant emission rate scaling as Γ¯SR∝N ¯Γ1 D for average atom number 0.19 ≲N ¯≲2.6 atoms, where Γ1 D/Γ'=1.0 ±0.1 is the peak single-atom radiative decay rate into the PCW guided mode, and Γ' is the radiative decay rate into all the other channels. These advances provide new tools for investigations of photon-mediated atom-atom interactions in the many-body regime.

  13. Focused US system for MR imaging-guided tumor ablation.

    PubMed

    Cline, H E; Hynynen, K; Watkins, R D; Adams, W J; Schenck, J F; Ettinger, R H; Freund, W R; Vetro, J P; Jolesz, F A

    1995-03-01

    To measure the performance characteristics of a focused ultrasound (US) system for magnetic resonance (MR) imaging-guided tumor ablation. The authors constructed a focused US system for MR imaging-guided tumor ablation. The location of the heated region and thermal dose were monitored with temperature-sensitive MR images obtained in phantoms and rabbit skeletal muscle after application of each sonic pulse. The region heated by the focused ultrasound beam was within 1 mm of that observed on temperature-sensitive fast gradient-echo MR images of in vivo rabbit skeletal muscle. Analysis of heat flow and the rate of coagulation necrosis provided an estimate of the size of the ablated region that was in agreement with experimental findings. MR imaging provides target definition and control for thermal therapy in regions of variable perfusion or in tissues that are not well characterized.

  14. RF Pulse Design using Nonlinear Gradient Magnetic Fields

    PubMed Central

    Kopanoglu, Emre; Constable, R. Todd

    2014-01-01

    Purpose An iterative k-space trajectory and radio-frequency (RF) pulse design method is proposed for Excitation using Nonlinear Gradient Magnetic fields (ENiGMa). Theory and Methods The spatial encoding functions (SEFs) generated by nonlinear gradient fields (NLGFs) are linearly dependent in Cartesian-coordinates. Left uncorrected, this may lead to flip-angle variations in excitation profiles. In the proposed method, SEFs (k-space samples) are selected using a Matching-Pursuit algorithm, and the RF pulse is designed using a Conjugate-Gradient algorithm. Three variants of the proposed approach are given: the full-algorithm, a computationally-cheaper version, and a third version for designing spoke-based trajectories. The method is demonstrated for various target excitation profiles using simulations and phantom experiments. Results The method is compared to other iterative (Matching-Pursuit and Conjugate Gradient) and non-iterative (coordinate-transformation and Jacobian-based) pulse design methods as well as uniform density spiral and EPI trajectories. The results show that the proposed method can increase excitation fidelity significantly. Conclusion An iterative method for designing k-space trajectories and RF pulses using nonlinear gradient fields is proposed. The method can either be used for selecting the SEFs individually to guide trajectory design, or can be adapted to design and optimize specific trajectories of interest. PMID:25203286

  15. How to use saturation monitoring in newborns.

    PubMed

    McVea, Steven; McGowan, Michael; Rao, Bharathi

    2018-05-10

    Pulse oximetry is a first-line monitoring tool, used in neonatal medicine routinely as a part of continuous monitoring during intensive care. It is also used to guide response to resuscitation and as a screening tool for congenital heart disease. Despite its widespread use, many healthcare providers are unaware of the underlying principles and limitations of pulse oximetry in neonates. In this article, we will discuss the physiological and technological principles behind the use of saturation monitoring and its use in neonatal practice. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  16. Military Applications of Fiber Optics Technology

    DTIC Science & Technology

    1989-05-01

    Research Projects Agency DNA Defense Nuclear Agency EMI Electromagnetic interference EMP Electromagnetic pulse FET Field effect transistor FOFA Follow...Organization SEED Self electro-optic effect device TBM Tactical ballistic missile TOW Tube launched, optically tracked, wire-guided UAV Unmanned aerial vehicle...systems, coupled with novel but effective transducing technology, have set the stage for a powerful class of fiber optic sensors. 8 Optical fibers have

  17. Guide to Canadian Aerospace Related Industries,

    DTIC Science & Technology

    1986-02-28

    Contract with Environmental Research and Code: ANA Development (US). Address: 240 Brooksbank Ave Digital Radar - Contract with Fundacao Educacional ...range from coal ings. The company is especially well known for its innovative engi- mining (methane) applications in Gillette, Wyoming to carbon...an order of magnitude higher than those provided by Atlantis also offers R&D and manufacturing services, especially standard tunnel diode pulse

  18. Stanford MFEL and Near Infrared Science Center

    DTIC Science & Technology

    2011-01-28

    guiding procedures for restoration of hearing— cochlear implants. Multifaceted approaches have been taken to understand the molecular and cellular...accompanying phenomena of cavitation, liquid flow and heat transfer in various biological tissues. In the field of laser surgery with ultrashort pulses...using yeast cell surface display, the Cochran group has generated EGF mutant libraries and have screened them by flow cytometry using fluorescently

  19. Plasma devices to guide and collimate a high density of MeV electrons.

    PubMed

    Kodama, R; Sentoku, Y; Chen, Z L; Kumar, G R; Hatchett, S P; Toyama, Y; Cowan, T E; Freeman, R R; Fuchs, J; Izawa, Y; Key, M H; Kitagawa, Y; Kondo, K; Matsuoka, T; Nakamura, H; Nakatsutsumi, M; Norreys, P A; Norimatsu, T; Snavely, R A; Stephens, R B; Tampo, M; Tanaka, K A; Yabuuchi, T

    2004-12-23

    The development of ultra-intense lasers has facilitated new studies in laboratory astrophysics and high-density nuclear science, including laser fusion. Such research relies on the efficient generation of enormous numbers of high-energy charged particles. For example, laser-matter interactions at petawatt (10(15) W) power levels can create pulses of MeV electrons with current densities as large as 10(12) A cm(-2). However, the divergence of these particle beams usually reduces the current density to a few times 10(6) A cm(-2) at distances of the order of centimetres from the source. The invention of devices that can direct such intense, pulsed energetic beams will revolutionize their applications. Here we report high-conductivity devices consisting of transient plasmas that increase the energy density of MeV electrons generated in laser-matter interactions by more than one order of magnitude. A plasma fibre created on a hollow-cone target guides and collimates electrons in a manner akin to the control of light by an optical fibre and collimator. Such plasma devices hold promise for applications using high energy-density particles and should trigger growth in charged particle optics.

  20. SU-F-J-225: Histology Study of MR Guided Pulsed Focused Ultrasound On Treatment of Prostate Cancer in Vivo

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Chen, L; Cvetkovic, D; Chen, X

    Purpose: Our previous study demonstrated significant tumor growth delay in the mice treated with pulsed high intensity focused ultrasound (pHIFU). The purpose of this study is to understand the cell killing mechanisms of pHIFU. Methods: Prostate cancer cells (LNCaP), were grown orthotopically in 17 nude mice. Tumor-bearing mice were treated using pHIFU with an acoustic power of 25W, pulse width 100msec and 300 pulses in one sonication under MR guidance. Mutiple sonications were used to cover the whole tumor volume. The temperature (less than 40 degree centigrade in the focal spot) was monitored using MR thermometry. Animals were euthanized atmore » pre-determined time points (n=2) after treatment: 0 hours; 6 hrs; 24 hrs; 48 hrs; 4 days and 7 days. Two tumorbearing mice were used as control. Three tumor-bearing mice were treated with radiation (RT, 2 Gy) using 6 MV photon beams. RT treated mice were euthanized at 0 hr, 6 hrs and 24 hrs. The tumors were processed for immunohistochemical (IHC) staining for PARP (a surrogate of apoptosis). A multispectral imaging analysis system was used to quantify the expression of PARP staining. Cell apoptosis was calculated based on the PARP expression level using the DAB analysis software. Results: Our data showed that PARP related apoptosis peaked at 48 hrs and 7 days in pHIFU treated mice, which is comparable to that for the RT group at 24 hrs. The preliminary results from this study were consistent with our previous study on tumor growth delay using pHIFU. Conclusion: Our results demonstrated that non-thermal pHIFU increased apoptotic tumor cell death through the PARP related pathway. MR guided pHIFU may have a great potential as a safe, noninvasive treatment modality for cancer therapy. This treatment modality may synergize with PARP inhibitors to achieve better therapeutic result.« less

  1. Image-guided smart laser system for precision implantation of cells in cartilage

    NASA Astrophysics Data System (ADS)

    Katta, Nitesh; Rector, John A.; Gardner, Michael R.; McElroy, Austin B.; Choy, Kevin C.; Crosby, Cody; Zoldan, Janet; Milner, Thomas E.

    2017-03-01

    State-of-the-art treatment for joint diseases like osteoarthritis focus on articular cartilage repair/regeneration by stem cell implantation therapy. However, the technique is limited by a lack of precision in the physician's imaging and cell deposition toolkit. We describe a novel combination of high-resolution, rapid scan-rate optical coherence tomography (OCT) alongside a short-pulsed nanosecond thulium (Tm) laser for precise cell seeding in cartilage. The superior beam quality of thulium lasers and wavelength of operation 1940 nm offers high volumetric tissue removal rates and minimizes the residual thermal footprint. OCT imaging enables targeted micro-well placement, precise cell deposition, and feature contrast. A bench-top system is constructed using a 15 W, 1940 nm, nanosecond-pulsed Tm fiber laser (500 μJ pulse energy, 100 ns pulse duration, 30kHz repetition rate) for removing tissue, and a swept source laser (1310 ± 70 nm, 100 kHz sweep rate) for OCT imaging, forming a combined Tm/OCT system - a "smart laser knife". OCT assists the smart laser knife user in characterizing cartilage to inform micro-well placement. The Tm laser creates micro-wells (2.35 mm diameter length, 1.5 mm width, 300 μm deep) and micro-incisions (1 mm wide, 200 μm deep) while OCT image-guidance assists and demonstrates this precision cutting and cell deposition with real-time feedback. To test micro-well creation and cell deposition protocol, gelatin phantoms are constructed mimicking cartilage optical properties and physiological structure. Cell viability is then assessed to illustrate the efficacy of the hydrogel deposition. Automated OCT feedback is demonstrated for cutting procedures to avoid important surface/subsurface structures. This bench-top smart laser knife system described here offers a new image-guided approach to precise stem cell seeding that can enhance the efficacy of articular cartilage repair.

  2. The new RLA test status

    NASA Astrophysics Data System (ADS)

    Smith, D. L.; Mazarakis, M. G.; Skogmo, P.; Bennett, L. F.; Olson, W. R.; George, M.; Harden, M. J.; Turman, B. N.; Moya, S. A.; Henderson, J. L.

    The Recirculating Linear Accelerator (RLA) is returning to operation with a new relativistic electron beam (REB) injector and a modified accelerating cavity. Upon completion of our pulsed-power test program, we will capture the injected beam on an Ion Focussed Regime (IFR) guiding channel in either a spiral or a closed racetrack drift tube. The relativistic beam will recirculate for four passes through two accelerating cavities, in phase with the ringing cavity voltage, and increase to 8--12 MeV before being extracted. We designed the METGLAS ribbon-wound core, inductively isolated, four-stage injector to produce beam parameters of 4 MeV, 10--20 kA, and 40--55 ns FWHM. The three-line radial cavity is being modified to improve the 1-MV accelerating pulse shape while an advanced cavity design study is in progress. This is a continuation of the Sandia National Laboratory program to develop compact, high-voltage gradient, linear induction accelerators. The RLA concept is based on guiding an injected REB with an IFR channel. This channel is formed from a plasma created with a low energy electron beam inside a beam line containing about 2 x 10(exp -4) Torr of argon. The REB is injected onto the IFR channel and is transported down the beamline through a water dielectric accelerating cavity based on the ET-2 design. If the round-tip path of the beam matches the period of the cavity, the REB can be further accelerated by the ringing waveform on every subsequent pass. We have installed the new REB injector because we need a higher amplitude, longer duration, flat-topped pulse shape with a colder beam than that produced by the previous injector. We made extensive use of computer simulations in the form of network solver and electrostatic field stress analysis codes to aid in the design and modifications for the new RLA. The pulsed-power performance of the RLA injector and cavity and the associated driving hardware are discussed.

  3. Photonic Switching Devices Using Light Bullets

    NASA Technical Reports Server (NTRS)

    Goorjian, Peter M. (Inventor)

    1999-01-01

    A unique ultra-fast, all-optical switching device or switch is made with readily available, relatively inexpensive, highly nonlinear optical materials. which includes highly nonlinear optical glasses, semiconductor crystals and/or multiple quantum well semiconductor materials. At the specified wavelengths. these optical materials have a sufficiently negative group velocity dispersion and high nonlinear index of refraction to support stable light bullets. The light bullets counter-propagate through, and interact within the waveguide to selectively change each others' directions of propagation into predetermined channels. In one embodiment, the switch utilizes a rectangularly planar slab waveguide. and further includes two central channels and a plurality of lateral channels for guiding the light bullets into and out of the waveguide. An advantage of the present all-optical switching device lies in its practical use of light bullets, thus preventing the degeneration of the pulses due to dispersion and diffraction at the front and back of the pulses. Another advantage of the switching device is the relative insensitivity of the collision process to the time difference in which the counter-propagating pulses enter the waveguide. since. contrary to conventional co-propagating spatial solitons, the relative phase of the colliding pulses does not affect the interaction of these pulses. Yet another feature of the present all-optical switching device is the selection of the light pulse parameters which enables the generation of light bullets in nonlinear optical materials. including highly nonlinear optical glasses and semiconductor materials such as semiconductor crystals and/or multiple quantum well semiconductor materials.

  4. [Comprehensive testing system for cardiorespiratory interaction research].

    PubMed

    Zhang, Zhengbo; Wang, Buqing; Wang, Weidong; Zheng, Jiewen; Liu, Hongyun; Li, Kaiyuan; Sun, Congcong; Wang, Guojing

    2013-04-01

    To investigate the modulation effects of breathing movement on cardiovascular system and to study the physiological coupling relationship between respiration and cardiovascular system, we designed a comprehensive testing system for cardiorespiratory interaction research. This system, comprising three parts, i. e. physiological signal conditioning unit, data acquisition and USB medical isolation unit, and a PC based program, can acquire multiple physiological data such as respiratory flow, rib cage and abdomen movement, electrocardiograph, artery pulse wave, cardiac sounds, skin temperature, and electromyography simultaneously under certain experimental protocols. Furthermore this system can be used in research on short-term cardiovascular variability by paced breathing. Preliminary experiments showed that this system could accurately record rib cage and abdomen movement under very low breathing rate, using respiratory inductive plethysmography to acquire respiration signal in direct-current coupling mode. After calibration, this system can be used to estimate ventilation non-intrusively and correctly. The PC based program can generate audio and visual biofeedback signal, and guide the volunteers to perform a slow and regular breathing. An experiment on healthy volunteers showed that this system was able to guide the volunteers to do slow breathing effectively and simultaneously record multiple physiological data during the experiments. Signal processing techniques were used for off-line data analysis, such as non-invasive ventilation calibration, QRS complex wave detection, and respiratory sinus arrhythmia and pulse wave transit time calculation. The experiment result showed that the modulation effect on RR interval, respiratory sinus arrhythmia (RSA), pulse wave transit time (PWTT) by respiration would get stronger with the going of the slow and regular breathing.

  5. Steering by hearing: a bat's acoustic gaze is linked to its flight motor output by a delayed, adaptive linear law.

    PubMed

    Ghose, Kaushik; Moss, Cynthia F

    2006-02-08

    Adaptive behaviors require sensorimotor computations that convert information represented initially in sensory coordinates to commands for action in motor coordinates. Fundamental to these computations is the relationship between the region of the environment sensed by the animal (gaze) and the animal's locomotor plan. Studies of visually guided animals have revealed an anticipatory relationship between gaze direction and the locomotor plan during target-directed locomotion. Here, we study an acoustically guided animal, an echolocating bat, and relate acoustic gaze (direction of the sonar beam) to flight planning as the bat searches for and intercepts insect prey. We show differences in the relationship between gaze and locomotion as the bat progresses through different phases of insect pursuit. We define acoustic gaze angle, theta(gaze), to be the angle between the sonar beam axis and the bat's flight path. We show that there is a strong linear linkage between acoustic gaze angle at time t [theta(gaze)(t)] and flight turn rate at time t + tau into the future [theta(flight) (t + tau)], which can be expressed by the formula theta(flight) (t + tau) = ktheta(gaze)(t). The gain, k, of this linkage depends on the bat's behavioral state, which is indexed by its sonar pulse rate. For high pulse rates, associated with insect attacking behavior, k is twice as high compared with low pulse rates, associated with searching behavior. We suggest that this adjustable linkage between acoustic gaze and motor output in a flying echolocating bat simplifies the transformation of auditory information to flight motor commands.

  6. Noninvasive treatment of deep venous thrombosis using pulsed ultrasound cavitation therapy (histotripsy) in a porcine model.

    PubMed

    Maxwell, Adam D; Owens, Gabe; Gurm, Hitinder S; Ives, Kimberly; Myers, Daniel D; Xu, Zhen

    2011-03-01

    This study evaluated histotripsy as a noninvasive, image-guided method of thrombolysis in a porcine model of deep vein thrombosis. Histotripsy therapy uses short, high-intensity, focused ultrasound pulses to cause mechanical breakdown of targeted soft tissue by acoustic cavitation, which is guided by real-time ultrasound imaging. This is an in vivo feasibility study of histotripsy thrombolysis. Acute thrombi were formed in the femoral vein of juvenile pigs weighing 30-40 kg by balloon occlusion with two catheters and thrombin infusion. A 10-cm-diameter 1-MHz focused transducer was used for therapy. An 8-MHz ultrasound imager was used to align the clot with the therapy focus. Therapy consisted of five cycle pulses delivered at a rate of 1 kHz and peak negative pressure between 14 and 19 MPa. The focus was scanned along the long axis of the vessel to treat the entire visible clot during ultrasound exposure. The targeted region identified by a hyperechoic cavitation bubble cloud was visualized via ultrasound during treatment. Thrombus breakdown was apparent as a decrease in echogenicity within the vessel in 10 of 12 cases and in 7 cases improved flow through the vein as measured by color Doppler. Vessel histology found denudation of vascular endothelium and small pockets of hemorrhage in the vessel adventitia and underlying muscle and fatty tissue, but perforation of the vessel wall was never observed. The results indicate histotripsy has potential for development as a noninvasive treatment for deep vein thrombosis. Copyright © 2011 SIR. Published by Elsevier Inc. All rights reserved.

  7. Ultrasound guided electrochemotherapy for the treatment of a clear cell thymoma in a cat

    PubMed Central

    Spugnini, Enrico Pierluigi; Menicagli, Francesco; Pettorali, Michela; Baldi, Alfonso

    2017-01-01

    A twelve-year-old male castrated domestic shorthair cat was presented for rapidly progressing respiratory distress. The cat was depressed, tachypneic and moderately responsive. Ultrasonography showed a mediastinal mass associated with a significant pleural effusion that needed tapping every five to seven days. Ultrasound guided biopsy yielded a diagnosis of clear cell thymoma upon histopathology. After complete staging procedures, the owner elected to treat the cat with electrochemotherapy (ECT) using systemic bleomycin. Two sessions of ultrasound guided ECT were performed at two week intervals with trains of biphasic electric pulses applied using needle electrodes until complete coverage of the area was achieved. The treatment was well tolerated and resulted in partial remission (PR). Additional sessions were performed on a monthly basis. The cat is still in PR after fourteen months. ECT resulted in improved local control and should be considered among the available adjuvant treatments in pets carrying visceral tumors. PMID:28331834

  8. Guided-wave phase-matched second-harmonic generation in KTiOPO4 waveguide produced by swift heavy-ion irradiation

    NASA Astrophysics Data System (ADS)

    Cheng, Yazhou; Jia, Yuechen; Akhmadaliev, Shavkat; Zhou, Shengqiang; Chen, Feng

    2014-11-01

    We report on the guided-wave second-harmonic generation in a KTiOPO4 nonlinear optical waveguide fabricated by a 17 MeV O5+ ion irradiation at a fluence of 1.5×1015 ions/cm2. The waveguide guides light along both TE and TM polarizations, which is suitable for phase-matching frequency doubling. Second harmonics of green light at a wavelength of 532 nm have been generated through the KTiOPO4 waveguide platform under an optical pump of fundamental wave at 1064 nm in both continuous-wave and pulsed regimes, reaching optical conversion efficiencies of 5.36%/W and 11.5%, respectively. The propagation losses have been determined to be ˜3.1 and ˜5.7 dB/cm for the TE and TM polarizations at a wavelength of 632.8 nm, respectively.

  9. Direct experimental observation of the gas density depression effect using a two-bunch X-ray FEL beam.

    PubMed

    Feng, Y; Schafer, D W; Song, S; Sun, Y; Zhu, D; Krzywinski, J; Robert, A; Wu, J; Decker, F J

    2018-01-01

    The experimental observation of the depression effect in gas devices designed for X-ray free-electron lasers (FELs) is reported. The measurements were carried out at the Linac Coherent Light Source using a two-bunch FEL beam at 6.5 keV with 122.5 ns separation passing through an argon gas cell. The relative intensities of the two pulses of the two-bunch beam were measured, after and before the gas cell, from X-ray scattering off thin targets by using fast diodes with sufficient temporal resolution. At a cell pressure of 140 hPa, it was found that the after-to-before ratio of the intensities of the second pulse was about 17% ± 6% higher than that of the first pulse, revealing lower effective attenuation of the gas cell due to heating by the first pulse and subsequent gas density reduction in the beam path. This measurement is important in guiding the design and/or mitigating the adverse effects in gas devices for high-repetition-rate FELs such as the LCLS-II and the European XFEL or other future high-repetition-rate upgrades to existing FEL facilities.

  10. Direct experimental observation of the gas density depression effect using a two-bunch X-ray FEL beam

    DOE PAGES

    Feng, Y.; Schafer, D. W.; Song, S.; ...

    2018-01-01

    The experimental observation of the depression effect in gas devices designed for X-ray free-electron lasers (FELs) is reported. The measurements were carried out at the Linac Coherent Light Source using a two-bunch FEL beam at 6.5 keV with 122.5 ns separation passing through an argon gas cell. The relative intensities of the two pulses of the two-bunch beam were measured, after and before the gas cell, from X-ray scattering off thin targets by using fast diodes with sufficient temporal resolution. At a cell pressure of 140 hPa, it was found that the after-to-before ratio of the intensities of the secondmore » pulse was about 17% ± 6% higher than that of the first pulse, revealing lower effective attenuation of the gas cell due to heating by the first pulse and subsequent gas density reduction in the beam path. Furthermore, this measurement is important in guiding the design and/or mitigating the adverse effects in gas devices for high-repetition-rate FELs such as the LCLS-II and the European XFEL or other future high-repetition-rate upgrades to existing FEL facilities.« less

  11. Direct experimental observation of the gas density depression effect using a two-bunch X-ray FEL beam

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Feng, Y.; Schafer, D. W.; Song, S.

    The experimental observation of the depression effect in gas devices designed for X-ray free-electron lasers (FELs) is reported. The measurements were carried out at the Linac Coherent Light Source using a two-bunch FEL beam at 6.5 keV with 122.5 ns separation passing through an argon gas cell. The relative intensities of the two pulses of the two-bunch beam were measured, after and before the gas cell, from X-ray scattering off thin targets by using fast diodes with sufficient temporal resolution. At a cell pressure of 140 hPa, it was found that the after-to-before ratio of the intensities of the secondmore » pulse was about 17% ± 6% higher than that of the first pulse, revealing lower effective attenuation of the gas cell due to heating by the first pulse and subsequent gas density reduction in the beam path. Furthermore, this measurement is important in guiding the design and/or mitigating the adverse effects in gas devices for high-repetition-rate FELs such as the LCLS-II and the European XFEL or other future high-repetition-rate upgrades to existing FEL facilities.« less

  12. Extracting the distribution of laser damage precursors on fused silica surfaces for 351 nm, 3 ns laser pulses at high fluences (20-150 J/cm2).

    PubMed

    Laurence, Ted A; Bude, Jeff D; Ly, Sonny; Shen, Nan; Feit, Michael D

    2012-05-07

    Surface laser damage limits the lifetime of optics for systems guiding high fluence pulses, particularly damage in silica optics used for inertial confinement fusion-class lasers (nanosecond-scale high energy pulses at 355 nm/3.5 eV). The density of damage precursors at low fluence has been measured using large beams (1-3 cm); higher fluences cannot be measured easily since the high density of resulting damage initiation sites results in clustering. We developed automated experiments and analysis that allow us to damage test thousands of sites with small beams (10-30 µm), and automatically image the test sites to determine if laser damage occurred. We developed an analysis method that provides a rigorous connection between these small beam damage test results of damage probability versus laser pulse energy and the large beam damage results of damage precursor densities versus fluence. We find that for uncoated and coated fused silica samples, the distribution of precursors nearly flattens at very high fluences, up to 150 J/cm2, providing important constraints on the physical distribution and nature of these precursors.

  13. Pulse transit time reveals drug kinetics on vascular changes affected by propofol.

    PubMed

    Lan, Yuan-Chun; Shen, Ching-Hui; Kang, Hsung-Ming; Chong, Fok-Ching

    2012-01-01

    Pulse transit time (PTT) is the duration in which a pulse wave travels between two arterial sites within the same cardiac cycle. The aim of our study is to use PTT to examine propofol's effects on the vascular system. Methods. We collected data from 50 healthy women, between 28 and 51 years old, who underwent gynaecological surgery under general anaesthesia. The general anaesthesia was induced with propofol injection (2 mg/kg). PTT measurements were obtained from the R-wave of electrocardiogram and the pulse wave of photoplethysmograph. Two PTT values were obtained; one before (the control) and the other after propofol injection. The results were analysed by Student's t-test. Results. After propofol injection, the PTT was prolonged. The change in the PTT value from that of baseline was significant statistically (P < 0.05, by Student's t-test). The PTT change over time correlated with the degree of vasodilatation over time. Monitoring of PTT not only revealed the magnitude of vascular changes but also demonstrated the onset of vascular dilation, its peak and duration. We conclude that PTT is a useful guide in monitoring the drug kinetics of propofol.

  14. Performance of laser guide star adaptive optics at Lick Observatory

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Olivier, S.S.; An, J.; Avicola, K.

    1995-07-19

    A sodium-layer laser guide star adaptive optics system has been developed at Lawrence Livermore National Laboratory (LLNL) for use on the 3-meter Shane telescope at Lick Observatory. The system is based on a 127-actuator continuous-surface deformable mirror, a Hartmann wavefront sensor equipped with a fast-framing low-noise CCD camera, and a pulsed solid-state-pumped dye laser tuned to the atomic sodium resonance line at 589 nm. The adaptive optics system has been tested on the Shane telescope using natural reference stars yielding up to a factor of 12 increase in image peak intensity and a factor of 6.5 reduction in image fullmore » width at half maximum (FWHM). The results are consistent with theoretical expectations. The laser guide star system has been installed and operated on the Shane telescope yielding a beam with 22 W average power at 589 nm. Based on experimental data, this laser should generate an 8th magnitude guide star at this site, and the integrated laser guide star adaptive optics system should produce images with Strehl ratios of 0.4 at 2.2 {mu}m in median seeing and 0.7 at 2.2 {mu}m in good seeing.« less

  15. Focusing electrode and coaxial reflector used for reducing the guiding magnetic field of the Ku-band foilless transit-time oscillator

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ling, Junpu; Zhang, Jiande; He, Juntao, E-mail: hejuntao12@163.com

    2014-08-15

    Based on the theoretical analysis of the intense relativistic electron beam propagation in the coaxial drift-tube, a focusing electrode and a coaxial reflector is proposed to lessen the demand of the coaxial Ku-band foilless transit-time oscillator (TTO) for the guiding magnetic field. Moreover, a Ku-band TTO with the focusing electrode and the coaxial reflector is designed and studied by particle in cell simulation. When the diode voltage is 390 kV, the beam current 7.8 kA, and the guiding magnetic field is only 0.3 T, the device can output 820 MW microwave pulse at 14.25 GHz by means of the simulation.more » However, for the device without them, the output power is only 320 MW. The primary experiments are also carried out. When the guiding magnetic field is 0.3 T, the output power of the device with the focusing electrode and the coaxial reflector is double that of the one without them. The simulation and experimental results prove that the focusing electrode and the coaxial reflector are effective on reducing the guiding magnetic field of the device.« less

  16. Test-retest reliability of pulse amplitude tonometry measures of vascular endothelial function: implications for clinical trial design.

    PubMed

    McCrea, Cindy E; Skulas-Ray, Ann C; Chow, Mosuk; West, Sheila G

    2012-02-01

    Endothelial dysfunction is an important outcome for assessing vascular health in intervention studies. However, reliability of the standard non-invasive method (flow-mediated dilation) is a significant challenge for clinical applications and multicenter trials. We evaluated the repeatability of pulse amplitude tonometry (PAT) to measure change in pulse wave amplitude during reactive hyperemia (Itamar Medical Ltd, Caesarea, Israel). Twenty healthy adults completed two PAT tests (mean interval = 19.5 days) under standardized conditions. PAT-derived measures of endothelial function (reactive hyperemia index, RHI) and arterial stiffness (augmentation index, AI) showed strong repeatability (intra-class correlations = 0.74 and 0.83, respectively). To guide future research, we also analyzed sample size requirements for a range of effect sizes. A crossover design powered at 0.90 requires 28 participants to detect a 15% change in RHI. Our study is the first to show that PAT measurements are repeatable in adults over an interval greater than 1 week.

  17. Resonant Pump-dump Quantum Control of Solvated Dye Molecules with Phase Jumps

    NASA Astrophysics Data System (ADS)

    Konar, Arkaprabha; Lozovoy, Vadim; Dantus, Marcos

    2014-03-01

    Quantum coherent control of two photon and multiphoton excitation processes in atomic and condensed phase systems employing phase jumps has been well studied and understood. Here we demonstrate coherent quantum control of a two photon resonant pump-dump process in a complex solvated dye molecule. Phase jump in the frequency domain via a pulse shaper is employed to coherently enhance the stimulated emission by an order of magnitude when compared to transform limited pulses. Red shifted stimulated emission from successive low energy Stokes shifted excited states leading to narrowband emission are observed upon scanning the pi step across the excitation spectrum. A binary search space routine was also employed to investigate the effects of other types of phase jumps on stimulated emission and to determine the optimum phase that maximizes the emission. Understanding the underlying mechanism of this kind of enhancement will guide us in designing pulse shapes for enhancing stimulated emission, which can be further applied in the field of imaging.

  18. Single-photon imager based on a superconducting nanowire delay line

    NASA Astrophysics Data System (ADS)

    Zhao, Qing-Yuan; Zhu, Di; Calandri, Niccolò; Dane, Andrew E.; McCaughan, Adam N.; Bellei, Francesco; Wang, Hao-Zhu; Santavicca, Daniel F.; Berggren, Karl K.

    2017-03-01

    Detecting spatial and temporal information of individual photons is critical to applications in spectroscopy, communication, biological imaging, astronomical observation and quantum-information processing. Here we demonstrate a scalable single-photon imager using a single continuous superconducting nanowire that is not only a single-photon detector but also functions as an efficient microwave delay line. In this context, photon-detection pulses are guided in the nanowire and enable the readout of the position and time of photon-absorption events from the arrival times of the detection pulses at the nanowire's two ends. Experimentally, we slowed down the velocity of pulse propagation to ∼2% of the speed of light in free space. In a 19.7 mm long nanowire that meandered across an area of 286 × 193 μm2, we were able to resolve ∼590 effective pixels with a temporal resolution of 50 ps (full width at half maximum). The nanowire imager presents a scalable approach for high-resolution photon imaging in space and time.

  19. Finite element calculation of residual stress in dental restorative material

    NASA Astrophysics Data System (ADS)

    Grassia, Luigi; D'Amore, Alberto

    2012-07-01

    A finite element methodology for residual stresses calculation in dental restorative materials is proposed. The material under concern is a multifunctional methacrylate-based composite for dental restorations, activated by visible light. Reaction kinetics, curing shrinkage, and viscoelastic relaxation functions were required as input data on a structural finite element solver. Post cure effects were considered in order to quantify the residual stresses coming out from natural contraction with respect to those debited to the chemical shrinkage. The analysis showed for a given test case that residual stresses frozen in the dental restoration at uniform temperature of 37°C are of the same order of magnitude of the strength of the dental composite material per se.

  20. Considering student choice when selecting instructional strategies: a comparison of three prompting systems.

    PubMed

    Taber-Doughty, Teresa

    2005-01-01

    Three secondary age students with moderate intellectual disabilities learned to use the system of least prompts, a self-operated picture prompting system, and a self-operated auditory prompting system to use a copy machine and a debit machine. Both the effectiveness and efficiency of these prompting systems were compared. Additionally, student preference of instructional method was examined. The results demonstrated that each prompting system was effective and efficient with varying students when skill acquisition and duration of task performance were measured. All students demonstrated increased independence in completing both tasks. This study found that the preferred prompting systems were more effective in terms of both skill acquisition and duration for completing tasks for students.

  1. Design of an Integrated-System FARAD Thruster

    NASA Technical Reports Server (NTRS)

    Polzin, K.A.; Rose, R.F.; Miller, R.; Owens, T.

    2007-01-01

    Pulsed inductive plasma accelerators are spacecraft propulsion devices in which energy is stored in a capacitor and then discharged through an inductive coil. The device is electrodeless, inducing a current s heet in a plasma located near the face of the coil. The propellant is accelerated and expelled at a high exhaust velocity (order of 10 km/s) through the interaction of the plasma current and the induced magne tic field, The Faraday Accelerator with RF-Assisted Discharge (FARAD) thruster is a type of pulsed inductive plasma accelerator in which t he plasma is preionized by a mechanism separate from that used to for m the current sheet and accelerate the gas. Employing a separate preionization mechanism allows for the formation of an inductive current s heet at much lower discharge energies and voltages than those used in previous pulsed inductive accelerators like the Pulsed Inductive Thr uster (PIT). In this paper, we present the design of a benchtop FARAD thruster with all the subsystems (mass injection, preionization, and acceleration) integrated into a single unit. Design of the thruster follows the guidelines and similarity performance parameters presented elsewhere. The system is designed to use the ringing, RF-frequency s ignal produced by a discharging Vector Inversion Generator (VIG) to p reionize the gas. The acceleration stage operates on the order of 100 J/pulse and can be driven by several different pulsed powertrains. These include a simple capacitor coupled to the system, a Bernardes and Merryman configuration, and a pulsecompression circuit that takes a temporally broad, low current pulse and transforms it into a short, h igh current pulse. A set of applied magnetic field coils are integrated into the system to guide the preionized propellant as it spreads ov er the face of the inductive acceleration coil. The coils are operate d in a pulsed mode, and the thruster can be operated without using the coils to determine if there is a performance improvement gain realiz ed when an applied field is present.

  2. Precision of noninvasive hemoglobin-level measurement by pulse co-oximetry in patients admitted to intensive care units for severe gastrointestinal bleeds.

    PubMed

    Coquin, Julien; Dewitte, Antoine; Manach, Yannick Le; Caujolle, Marie; Joannes-Boyau, Olivier; Fleureau, Catherine; Janvier, Gérard; Ouattara, Alexandre

    2012-09-01

    Measurement of total hemoglobin, based on pulse co-oximetry, is a continuous and noninvasive method that has been principally evaluated in healthy volunteers subjected to hemodilution. We tested the hypothesis that its accuracy could adversely affect patients presenting with severe hemorrhage, which is traditionally associated with increased microvascular tone. Observational study. Twelve-bed mixed medico-surgical intensive care unit. Thirty-three patients admitted to our critical care unit for gastrointestinal bleeds were included. A spectrophotometric sensor was positioned on the patient's fingertip and connected to a pulse co-oximeter. During the first 24 hrs following admission, venous hemoglobin level was determined at the laboratory every 8 hrs and was compared with hemoglobin levels displayed on the pulse co-oximeter measurements screen and/or measured from capillary blood using a portable photometer. The primary end point was the percentage of inaccurate measurements, which were defined as >15% difference compared with reference values or their unavailability for any technical reason. Twenty-five (19%) measurements of pulse co-oximeter measurements were unavailable from the screen. Pulse co-oximeter measurements and capillary hemoglobin levels were significantly correlated to venous hemoglobin level. For venous hemoglobin level compared with pulse co-oximeter measurements (n = 105), and for venous hemoglobin level compared with capillary hemoglobin levels (n = 111), the biases were, respectively, 1.0 ± 1.9 g dL and 0.4 ± 1.0 g dL (p < .05). The proportion of inaccurate measurements was significantly higher for pulse co-oximeter measurements (56% vs. 15%, p < .05). Although the use of norepinephrine did not affect concordance parameters, unavailability of measurements was frequently observed (42% vs. 15%, p < .05). Determination of pulse co-oximetry-based hemoglobin in patients presenting with severe gastrointestinal bleeds can be inaccurate, which renders its use to guide transfusion decisions potentially hazardous. The unavailability of measurements, especially during vasopressor infusion, represents another serious limitation for hemorrhagic patients.

  3. Comparison of the lowest-order transverse-electric (TE1) and transverse-magnetic (TEM) modes of the parallel-plate waveguide for terahertz pulse applications.

    PubMed

    Mendis, Rajind; Mittleman, Daniel M

    2009-08-17

    We present a comprehensive experimental study comparing the propagation characteristics of the virtually unknown TE(1) mode to the well-known TEM mode of the parallel-plate waveguide (PPWG), for THz pulse applications. We demonstrate that it is possible to overcome the undesirable effects caused by the TE(1) mode's inherent low-frequency cutoff, making it a viable THz wave-guiding option, and that for certain applications, the TE(1) mode may even be more desirable than the TEM mode. This study presents a whole new dimension to the THz technological capabilities offered by the PPWG, via the possible use of the TE(1) mode. (c) 2009 Optical Society of America

  4. Numerical and Experimental Characterization of a Composite Secondary Bonded Adhesive Lap Joint Using the Ultrasonics method

    NASA Astrophysics Data System (ADS)

    Kumar, M. R.; Ghosh, A.; Karuppannan, D.

    2018-05-01

    The construction of aircraft using advanced composites have become very popular during the past two decades, in which many innovative manufacturing processes, such as cocuring, cobonding, and secondary bonding processes, have been adopted. The secondary bonding process has become less popular than the other two ones because of nonavailability of process database and certification issues. In this article, an attempt is made to classify the quality of bonding using nondestructive ultrasonic inspection methods. Specimens were prepared and tested using the nondestructive ultrasonic Through Transmission (TT), Pulse Echo (PE), and air coupled guided wave techniques. It is concluded that the ultrasonic pulse echo technique is the best one for inspecting composite secondary bonded adhesive joints.

  5. Laser direct writing of thin-film copper structures as a modification of lithographic processes

    NASA Astrophysics Data System (ADS)

    Meyer, F.; Ostendorf, A.; Stute, U.

    2007-04-01

    This paper presents a flexible, mask-free and efficient technique for UV-laser micropatterning of photosensitive resist by laser direct writing (LDW). Photo resist spun on gold sputtered silicon wafers has been laser structured by a scanner guided 266nm DPSSL and electroplated. Ablation behaviour and optimum seed layer preparation in relation to parameters like pulse energy, scanning speed and number of scanned cycles and the electroplating results are discussed. The resulting adhesive strength was measured by a µ-sear device and the gold seed layer-plated copper interface investigated by SEM and EDX to explain correlation to identified bonding behaviour. Improved adhesive strength was observed with higher laser pulse energy and reduced number of cycle.

  6. Hybrid fiber-rod laser

    DOEpatents

    Beach, Raymond J.; Dawson, Jay W.; Messerly, Michael J.; Barty, Christopher P. J.

    2012-12-18

    Single, or near single transverse mode waveguide definition is produced using a single homogeneous medium to transport both the pump excitation light and generated laser light. By properly configuring the pump deposition and resulting thermal power generation in the waveguide device, a thermal focusing power is established that supports perturbation-stable guided wave propagation of an appropriately configured single or near single transverse mode laser beam and/or laser pulse.

  7. Fluorescence imaging in the upper gastrointestinal tract for the detection of dysplasic changes

    NASA Astrophysics Data System (ADS)

    Sukowski, Uwe; Ebert, Bernd; Ortner, Marianne; Mueller, Karsten; Voderholzer, W.; Weber-Eibel, J.; Dietel, M.; Lochs, Herbert; Rinneberg, Herbert H.

    2001-10-01

    During endoscopy of the esophagus fluorescence images were recorded at a delay of 20 ns after pulsed laser excitation simultaneously with conventional reflected white light images. To label malignant cells (dysplasia, tumor) 5-aminolaevulinic acid was applied prior to fluorescence guided bi-opsy. In this way pre-malignant and malignant lesions were detected not seen previously during routine endoscopy.

  8. Cerebral Oxygen Saturation to Guide Oxygen Delivery in Preterm Neonates for the Immediate Transition after Birth: A 2-Center Randomized Controlled Pilot Feasibility Trial.

    PubMed

    Pichler, Gerhard; Urlesberger, Berndt; Baik, Nariae; Schwaberger, Bernhard; Binder-Heschl, Corinna; Avian, Alexander; Pansy, Jasmin; Cheung, Po-Yin; Schmölzer, Georg Marcus

    2016-03-01

    To assess if monitoring of cerebral regional tissue oxygen saturation (crSO2) using near-infrared spectroscopy (NIRS) to guide respiratory and supplemental oxygen support reduces burden of cerebral hypoxia and hyperoxia in preterm neonates during resuscitation after birth. Preterm neonates <34(+0) weeks of gestation were included in a prospective randomized controlled pilot feasibility study at 2 tertiary level neonatal intensive care units. In a NIRS-visible group, crSO2 monitoring in addition to pulse oximetry was used to guide respiratory and supplemental oxygen support during the first 15 minutes after birth. In a NIRS-not-visible group, only pulse oximetry was used. The primary outcomes were burden of cerebral hypoxia (<10th percentile) or hyperoxia (>90th percentile) measured in %minutes crSO2 during the first 15 minutes after birth. Secondary outcomes were all cause of mortality and/or cerebral injury and neurologic outcome at term age. Allocation sequence was 1:1 with block-randomization of 30 preterm neonates at each site. In the NIRS-visible group burden of cerebral hypoxia in %minutes, crSO2 was halved, and the relative reduction was 55.4% (95% CI 37.6-73.2%; P = .028). Cerebral hyperoxia was observed in NIRS-visible group in 3 neonates with supplemental oxygen and in NIRS-not-visible group in 2. Cerebral injury rate and neurologic outcome at term age was similar in both groups. Two neonates died in the NIRS-not-visible group and none in the NIRS-visible group. No severe adverse reactions were observed. Reduction of burden of cerebral hypoxia during immediate transition and resuscitation after birth is feasible by crSO2 monitoring to guide respiratory and supplemental oxygen support. ClinicalTrials.gov: NCT02017691. Copyright © 2016 Elsevier Inc. All rights reserved.

  9. Desagregation des debits mensuels en debits journaliers

    NASA Astrophysics Data System (ADS)

    Ypou, Tanou Ya Kouassi

    A good estimate of the historical natural flow of water in a water system, allows an appropriate management of reservoirs of hydroelectric plants. This management is a guarantee for efficient planning of hydropower production. The reconstruction of the real natural inputs with quality features for the periods before and after the impoundment of reservoirs is sought by HQ. The implementation of a good quality daily historical data from monthly data remains a major concern both for HQ and for the scientific community. Beyond the benefits of mastering simulations of the basin's hydrological behavior in water systems, this study allows the establishment of appropriate measures to protect the population and the various properties located in riparian areas of water systems. The main objective of the study is the breakdown of monthly flows in daily flows. This study is in the business context of HQ. To reconstruct the historical supply of water systems, HSAMI and HYDROTEL models are used. Different methods have been used by HQ to constitute the daily historical rates. So far, a good quality of the reconstituted daily data analysis illustrates the serious discrepancies and errors in those series. Several previous studies in the literature have attempted to reconstruct the daily flow rates from historical monthly series, but as explained in the report, these different approaches have results that do not represent the reality of HQ's water systems. Clearly the methods are not effective in the operational framework of Hydro-Quebec. This report presents an optimized use based on the approach HSAMI and HYDROTEL models in order to transform the flow of rain for the reconstruction of natural flow series. This approach is applied to Outardes's and Saint-Maurice's water systems with the weather and physical field data available. Input the hydrological data are validated by a process of analyzing data quality, specific flow and evaporation parameters. Input the metrological data has been analysis by Statistics, climate and water for weather series criteria. An automatic calibration of the two models is made with the Matlab software. The results of the calibration of Outardes's and Saint-Maurice's water systems are presented in this report. The modeling of ground conditions is made for input data needs of different models using the features included in the models are generally presented in this report and in particularly the model for HYDROTEL and PHYSITEL. The historical simulation flows is performed using meteorological data and physical field data on the periods of 1965 to 2014. Based on the quality of input data available and the goal of generating daily historical supply series using monthly series of natural inputs, the quality criteria have been defined to qualify the model to choose. Indeed, the quality criteria for comparing the two models are the criterion of NSE and KGE. Analysis of the results led to the conclusion that the HYDROTEL model is most appropriate in the operational framework of HQ to disaggregate monthly historical series of daily flows in series. The HYDROTEL model enabled to disaggregate monthly debits daily flows. The daily discharges simulated ponds Beaumont, Vermillion, La tuque are presented and analyzed in this report. Keywords: disaggregation, natural flow, HYDROTEL, HSAMI, data reconstruction .

  10. Retinal response of Macaca mulatta to picosecond laser pulses of varying energy and spot size.

    PubMed

    Roach, William P; Cain, Clarence P; Narayan, Drew G; Noojin, Gary D; Boppart, Stephen A; Birngruber, Reginald; Fujimoto, James G; Toth, Cynthia A

    2004-01-01

    We investigate the relationship between the laser beam at the retina (spot size) and the extent of retinal injury from single ultrashort laser pulses. From previous studies it is believed that the retinal effect of single 3-ps laser pulses should vary in extent and location, depending on the occurrence of laser-induced breakdown (LIB) at the site of laser delivery. Single 3-ps pulses of 580-nm laser energy are delivered over a range of spot sizes to the retina of Macaca mulatta. The retinal response is captured sequentially with optical coherence tomography (OCT). The in vivo OCT images and the extent of pathology on final microscopic sections of the laser site are compared. With delivery of a laser pulse with peak irradiance greater than that required for LIB, OCT and light micrographs demonstrate inner retinal injury with many intraretinal and/or vitreous hemorrhages. In contrast, broad outer retinal injury with minimal to no choriocapillaris effect is seen after delivery of laser pulses to a larger retinal area (60 to 300 microm diam) when peak irradiance is less than that required for LIB. The broader lesions extend into the inner retina when higher energy delivery produces intraretinal injury. Microscopic examination of stained fixed tissues provide better resolution of retinal morphology than OCT. OCT provides less resolution but could be guided over an in vivo, visible retinal lesion for repeated sampling over time during the evolution of the lesion formation. For 3-ps visible wavelength laser pulses, varying the spot size and laser energy directly affects the extent of retinal injury. This again is believed to be partly due to the onset of LIB, as seen in previous studies. Spot-size dependence should be considered when comparing studies of retinal effects or when pursuing a specific retinal effect from ultrashort laser pulses. Copyright 2004 Society of Photo-Optical Instrumentation Engineers.

  11. MR-guided pulsed high intensity focused ultrasound enhancement of docetaxel combined with radiotherapy for prostate cancer treatment

    NASA Astrophysics Data System (ADS)

    Mu, Zhaomei; Ma, C.-M.; Chen, Xiaoming; Cvetkovic, Dusica; Pollack, Alan; Chen, Lili

    2012-01-01

    The purpose of this study is to evaluate the efficacy of the enhancement of docetaxel by pulsed focused ultrasound (pFUS) in combination with radiotherapy (RT) for treatment of prostate cancer in vivo. LNCaP cells were grown in the prostates of male nude mice. When the tumors reached a designated volume by MRI, tumor bearing mice were randomly divided into seven groups (n = 5): (1) pFUS alone; (2) RT alone; (3) docetaxel alone; (4) docetaxel + pFUS (5) docetaxel + RT (6) docetaxel + pFUS + RT, and (7) control. MR-guided pFUS treatment was performed using a focused ultrasound treatment system (InSightec ExAblate 2000) with a 1.5T GE MR scanner. Animals were treated once with pFUS, docetaxel, RT or their combinations. Docetaxel was given by i.v. injection at 5 mg kg-1 before pFUS. RT was given 2 Gy after pFUS. Animals were euthanized 4 weeks after treatment. Tumor volumes were measured on MRI at 1 and 4 weeks post-treatment. Results showed that triple combination therapies of docetaxel, pFUS and RT provided the most significant tumor growth inhibition among all groups, which may have potential for the treatment of prostate cancer due to an improved therapeutic ratio.

  12. Towards in vivo laser coagulation and concurrent optical coherence tomography through double-clad fiber devices

    NASA Astrophysics Data System (ADS)

    Beaudette, Kathy; Lo, William; Villiger, Martin; Shishkov, Milen; Godbout, Nicolas; Bouma, Brett E.; Boudoux, Caroline

    2016-03-01

    There is a strong clinical need for an optical coherence tomography (OCT) system capable of delivering concurrent coagulation light enabling image-guided dynamic laser marking for targeted collection of biopsies, as opposed to a random sampling, to reduce false-negative findings. Here, we present a system based on double-clad fiber (DCF) capable of delivering pulsed laser light through the inner cladding while performing OCT through the core. A previously clinically validated commercial OCT system (NVisionVLE, Ninepoint Medical) was adapted to enable in vivo esophageal image-guided dynamic laser marking. An optimized DCF coupler was implemented into the system to couple both modalities into the DCF. A DCF-based rotary joint was used to couple light to the spinning DCF-based catheter for helical scanning. DCF-based OCT catheters, providing a beam waist diameter of 62μm at a working distance of 9.3mm, for use with a 17-mm diameter balloon sheath, were used for ex vivo imaging of a swine esophagus. Imaging results using the DCF-based clinical system show an image quality comparable with a conventional system with minimal crosstalk-induced artifacts. To further optimize DCF catheter optical design in order to achieve single-pulse marking, a Zemax model of the DCF output and its validation are presented.

  13. Emergency endotracheal intubation under fluoroscopy guidance for patients with acute dyspnea or asphyxia.

    PubMed

    Jiao, Dechao; Xie, Na; Han, Xinwei; Wu, Gang

    2016-11-01

    To evaluate the feasibility and effectiveness of emergency endotracheal intubation (EEI) under fluoroscopy guidance for patients with acute dyspnea or asphyxia. From October 2011 to October 2014, of 1521 patients with acute dyspnea or asphyxia who required EEI in 6 departments, 43 patients who experienced intubation difficulty or failure were entered into this study. Data on technical success, procedure time, complications, and clinical outcome were collected. The pulse oxygen saturation and Hugh-Jones classification changes were analyzed. Fluoroscopy-guided EEI was technically successful in all patients. Acute dyspnea had resolved in all patients with clinical success rate 100% after the procedure. There were no serious complications during or after the procedure. The pulse oxygen saturation and Hugh-Jones classification showed significant increase after EEI (P < .05). Further treatments, including tracheal stents (n = 21), surgical resection (n = 16), palliative tracheotomy (n = 4), and bronchoscopic treatment (n = 2), were performed 1 to 72 hours after EEI. During a mean follow-up period of 13.2 months, 13 patients had died and 30 patients remained alive without dyspnea. Fluoroscopy-guided EEI is a safe and feasible procedure, and may serve as an alternative treatment option for patients when traditional EEI is unsuccessful. Copyright © 2016 Elsevier Inc. All rights reserved.

  14. An Experimental Study of a Pulsed Electromagnetic Plasma Accelerator

    NASA Technical Reports Server (NTRS)

    Thio, Y. C. Francis; Eskridge, Richard; Lee, Mike; Smith, James; Martin, Adam; Markusic, Tom E.; Cassibry, Jason T.; Rodgers, Stephen L. (Technical Monitor)

    2002-01-01

    Experiments are being performed on the NASA Marshall Space Flight Center (MSFC) pulsed electromagnetic plasma accelerator (PEPA-0). Data produced from the experiments provide an opportunity to further understand the plasma dynamics in these thrusters via detailed computational modeling. The detailed and accurate understanding of the plasma dynamics in these devices holds the key towards extending their capabilities in a number of applications, including their applications as high power (greater than 1 MW) thrusters, and their use for producing high-velocity, uniform plasma jets for experimental purposes. For this study, the 2-D MHD modeling code, MACH2, is used to provide detailed interpretation of the experimental data. At the same time, a 0-D physics model of the plasma initial phase is developed to guide our 2-D modeling studies.

  15. 2-D Magnetohydrodynamic Modeling of A Pulsed Plasma Thruster

    NASA Technical Reports Server (NTRS)

    Thio, Y. C. Francis; Cassibry, J. T.; Wu, S. T.; Rodgers, Stephen L. (Technical Monitor)

    2002-01-01

    Experiments are being performed on the NASA Marshall Space Flight Center (MSFC) MK-1 pulsed plasma thruster. Data produced from the experiments provide an opportunity to further understand the plasma dynamics in these thrusters via detailed computational modeling. The detailed and accurate understanding of the plasma dynamics in these devices holds the key towards extending their capabilities in a number of applications, including their applications as high power (greater than 1 MW) thrusters, and their use for producing high-velocity, uniform plasma jets for experimental purposes. For this study, the 2-D MHD modeling code, MACH2, is used to provide detailed interpretation of the experimental data. At the same time, a 0-D physics model of the plasma initial phase is developed to guide our 2-D modeling studies.

  16. High power pulsed sources based on fiber amplifiers

    NASA Astrophysics Data System (ADS)

    Canat, Guillaume; Jaouën, Yves; Mollier, Jean-Claude; Bouzinac, Jean-Pierre; Cariou, Jean-Pierre

    2017-11-01

    Cladding-pumped rare-earth-doped fiber laser technologies are currently among the best sources for high power applications. Theses extremely compact and robust sources appoint them as good candidate for aeronautical and space applications. The double-clad (DC) fiber converts the poor beamquality of high-power large-area pump diodes from the 1st cladding to laser light at another wavelength guided in an active single-mode core. High-power coherent MOPA (Master Oscillator Power Amplifier) sources (several 10W CW or several 100W in pulsed regime) will soon be achieved. Unfortunately it also brings nonlinear effects which quickly impairs output signal distortions. Stimulated Brillouin scattering (SBS) and optical parametric amplification (OPA) have been shown to be strong limitations. Based on amplifier modeling and experiments we discuss the performances of these sources.

  17. Enhancement of maximum attainable ion energy in the radiation pressure acceleration regime using a guiding structure

    DOE PAGES

    Bulanov, S. S.; Esarey, E.; Schroeder, C. B.; ...

    2015-03-13

    Radiation Pressure Acceleration is a highly efficient mechanism of laser driven ion acceleration, with the laser energy almost totally transferrable to the ions in the relativistic regime. There is a fundamental limit on the maximum attainable ion energy, which is determined by the group velocity of the laser. In the case of a tightly focused laser pulses, which are utilized to get the highest intensity, another factor limiting the maximum ion energy comes into play, the transverse expansion of the target. Transverse expansion makes the target transparent for radiation, thus reducing the effectiveness of acceleration. Utilization of an external guidingmore » structure for the accelerating laser pulse may provide a way of compensating for the group velocity and transverse expansion effects.« less

  18. Superradiant Ka-band Cherenkov oscillator with 2-GW peak power

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Rostov, V. V.; Romanchenko, I. V.; Pedos, M. S.

    The generation of a 2-GW microwave superradiance (SR) pulses has been demonstrated at 29-GHz using a single-mode relativistic backward-wave oscillator possessing the beam-to-wave power conversion factor no worse than 100%. A record-breaking radiation power density in the slow-wave structure (SWS) of ∼1.5 GW/cm{sup 2} required the use of high guiding magnetic field (7 T) decreasing the beam losses to the SWS in strong rf fields. Despite the field strength at the SWS wall of 2 MV/cm, a single-pass transmission mode of a short SR pulse in the SWS allows one to obtain extremely high power density in subnanosecond time scale due tomore » time delay in the development of the breakdown phenomena.« less

  19. The status of the positron beam facility at NEPOMUC

    NASA Astrophysics Data System (ADS)

    Hugenschmidt, C.

    2011-01-01

    The NEutron induced POsitron source MUniCh NEPOMUC provides a high intensity positron beam with 9·108 moderated positrons per second with a primary beam energy of 1keV. After remoderation, the positron beam is magnetically guided to five experimental setups: a coincident Doppler-broadening spectrometer (CDBS), a positron annihilation induced Auger-electron spectrometer (PAES), a pulsed low-energy positron system (PLEPS) as well as an interface for providing a pulsed beam with further improved brightness. An apparatus for the production of the negatively charged positronium ion Ps- is currently in operation at the open multi-purpose beam port, where additional experiments can be realized. Within this contribution, an overview of the positron beam facility NEPOMUC with its instrumentation at the research reactor FRMII is given.

  20. Comparative study of LaNiO3/LaAlO3 heterostructures grown by pulsed laser deposition and oxide molecular beam epitaxy

    NASA Astrophysics Data System (ADS)

    Wrobel, F.; Mark, A. F.; Christiani, G.; Sigle, W.; Habermeier, H.-U.; van Aken, P. A.; Logvenov, G.; Keimer, B.; Benckiser, E.

    2017-01-01

    Variations in growth conditions associated with different deposition techniques can greatly affect the phase stability and defect structure of complex oxide heterostructures. We synthesized superlattices of the paramagnetic metal LaNiO3 and the large band gap insulator LaAlO3 by atomic layer-by-layer molecular beam epitaxy (MBE) and pulsed laser deposition (PLD) and compared their crystallinity and microstructure as revealed by high-resolution transmission electron microscopy images and resistivity. The MBE samples show a higher density of stacking faults but smoother interfaces and generally higher electrical conductivity. Our study identifies the opportunities and challenges of MBE and PLD growth and serves as a general guide for the choice of the deposition technique for perovskite oxides.

  1. User's Guide for ECAP2D: an Euler Unsteady Aerodynamic and Aeroelastic Analysis Program for Two Dimensional Oscillating Cascades, Version 1.0

    NASA Technical Reports Server (NTRS)

    Reddy, T. S. R.

    1995-01-01

    This guide describes the input data required for using ECAP2D (Euler Cascade Aeroelastic Program-Two Dimensional). ECAP2D can be used for steady or unsteady aerodynamic and aeroelastic analysis of two dimensional cascades. Euler equations are used to obtain aerodynamic forces. The structural dynamic equations are written for a rigid typical section undergoing pitching (torsion) and plunging (bending) motion. The solution methods include harmonic oscillation method, influence coefficient method, pulse response method, and time integration method. For harmonic oscillation method, example inputs and outputs are provided for pitching motion and plunging motion. For the rest of the methods, input and output for pitching motion only are given.

  2. Development of Low-Cost Method for Fabrication of Metal Neutron Guides

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Engelhaupt, Darell; Khaykovich, Boris; Romaine, Suzanne

    Neutron scattering is one of the most useful methods of studying the structure and dynamics of matter. US DOE neutron scattering research facilities at Oak Ridge National Laboratory are among the World’s most advanced, providing researchers with unmatched capabilities for probing the structure and properties of materials, including engineering and biological systems. This task is to develop a lower cost process to optimize and produce the required neutron guides capable of efficiently delivering neutron beams for tens of meters between neutron moderators and instruments. Therefore, our effort is to improve the performance and lower the production cost of neutron guides.more » Our approach aims at improving guide quality while controlling their rising costs by adopting a novel electroforming replication approach to their fabrication. These guides will be especially advantageous when used near the neutron source since the radiation resistance of nickel is superior to glass. Additionally, we are depositing low-stress nickel from an extremely low impurity solution completely free of stress-reducing agents, which nominally contain and impart sulfur, carbon and other elements that potentially activate in the neutron environment. This is achieved by using a pulsed periodically reversed current methodology. The best guides quote waviness of 0.1 mrad. It is reasonable to prepare just one mandrel of about 0.5 m long, for production of tens of guide segments, saving both the cost and supply time of guides to neutron facilities. We estimate that we can fabricate a single mandrel for the current cost of an individual one-meter guide, but from this, we can produce tens of meters of guide very inexpensively without mandrel refurbishment. While a multilayer coating will add to the overall cost, we expect this will be less than that of commercially available guides today. Therefore, we will produce higher quality guides, which are less susceptible to radiation damage, at the lower cost than those available today.« less

  3. Development of Low-Cost Method for Fabrication of Metal Neutron Guides

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Engelhaupt, Darell; Khaykovich, Boris; Romaine, Suzanne

    2017-12-19

    Neutron scattering is one of the most useful methods of studying the structure and dynamics of matter. US DOE neutron scattering research facilities at Oak Ridge National Laboratory are among the World’s most advanced, providing researchers with unmatched capabilities for probing the structure and properties of materials, including engineering and biological systems. This task is to develop a lower cost process to optimize and produce the required neutron guides capable of efficiently delivering neutron beams for tens of meters between neutron moderators and instruments. Therefore, our effort is to improve the performance and lower the production cost of neutron guides.more » Our approach aims at improving guide quality while controlling their rising costs by adopting a novel electroforming replication approach to their fabrication. These guides will be especially advantageous when used near the neutron source since the radiation resistance of nickel is superior to glass. Additionally, we are depositing low-stress nickel from an extremely low impurity solution completely free of stress-reducing agents, which nominally contain and impart sulfur, carbon and other elements that potentially activate in the neutron environment. This is achieved by using a pulsed periodically reversed current methodology. The best guides quote waviness of 0.1 mrad. It is reasonable to prepare just one mandrel of about 0.5 m long, for production of tens of guide segments, saving both the cost and supply time of guides to neutron facilities. We estimate that we can fabricate a single mandrel for the current cost of an individual one-meter guide, but from this, we can produce tens of meters of guide very inexpensively without mandrel refurbishment. While a multilayer coating will add to the overall cost, we expect this will be less than that of commercially available guides today. Therefore, we will produce higher quality guides, which are less susceptible to radiation damage, at the lower cost than those available today.« less

  4. Targeted disruption of deep-lying neocortical microvessels in rat using ultrashort laser pulses

    NASA Astrophysics Data System (ADS)

    Nishimura, Nozomi; Schaffer, Christopher B.; Friedman, Beth; Tsai, Philbert S.; Lyden, Patrick D.; Kleinfeld, David

    2004-06-01

    The study of neurovascular diseases such as vascular dementia and stroke require novel models of targeted vascular disruption in the brain. We describe a model of microvascular disruption in rat neocortex that uses ultrashort laser pulses to induce localized injury to specific targeted microvessels and uses two-photon microscopy to monitor and guide the photodisruption process. In our method, a train of high-intensity, 100-fs laser pulses is tightly focused into the lumen of a blood vessel within the upper 500 μm of cortex. Photodisruption induced by these laser pulses creates injury to a single vessel located at the focus of the laser, leaving the surrounding tissue intact. This photodisruption results in three modalities of localized vascular injury. At low power, blood plasma extravasation can be induced. The vessel itself remains intact, while serum is extravasated into the intercellular space. Localized ischemia caused by an intravascular clot results when the photodisruption leads to a brief disturbance of the vascular walls that initiates an endogenous clotting cascade. The formation of a localized thrombus stops the blood flow at the location of the photodisruption. A hemorrhage, defined as a large extravasation of blood including plasma and red blood cells, results when higher laser power is used. The targeted vessel does not remain intact.

  5. Experimental progress in positronium laser physics

    NASA Astrophysics Data System (ADS)

    Cassidy, David B.

    2018-03-01

    The field of experimental positronium physics has advanced significantly in the last few decades, with new areas of research driven by the development of techniques for trapping and manipulating positrons using Surko-type buffer gas traps. Large numbers of positrons (typically ≥106) accumulated in such a device may be ejected all at once, so as to generate an intense pulse. Standard bunching techniques can produce pulses with ns (mm) temporal (spatial) beam profiles. These pulses can be converted into a dilute Ps gas in vacuum with densities on the order of 107 cm-3 which can be probed by standard ns pulsed laser systems. This allows for the efficient production of excited Ps states, including long-lived Rydberg states, which in turn facilitates numerous experimental programs, such as precision optical and microwave spectroscopy of Ps, the application of Stark deceleration methods to guide, decelerate and focus Rydberg Ps beams, and studies of the interactions of such beams with other atomic and molecular species. These methods are also applicable to antihydrogen production and spectroscopic studies of energy levels and resonances in positronium ions and molecules. A summary of recent progress in this area will be given, with the objective of providing an overview of the field as it currently exists, and a brief discussion of some future directions.

  6. Plasma shield lasertripsy: in vitro studies.

    PubMed

    Bhatta, K M; Rosen, D I; Dretler, S P

    1989-10-01

    A technique for safer and more effective pulsed laser lithotripsy of urinary and biliary calculi was investigated in vitro. The technique involves enclosing the distal end of the laser delivery fiber in a "plasma shield." The plasma shield is a specially designed metal cap that serves to transfer the laser-induced mechanical impulse to the calculus while shielding surrounding tissue from direct laser exposure and thermal radiation. The metal cap also offers the advantage of effectively blunting the sharp fiber tip and improving its visualization under fluoroscopy. Plasma shield lithotripsy using a 200 micron quartz fiber inserted into a section of a modified 0.034 in. diameter stainless steel guide wire was tested in vitro on a variety of calculi and compared with results obtained using a 200 micron laser fiber applied directly. Calculi tested included cystine, struvite and calcium oxalate dihydrate urinary stones and pigmented cholesterol gallstones. The laser source was a flashlamp-pumped dye laser producing pulses of 1.2 microsecond duration and operated at a wavelength of 504 nm and pulse repetition frequency of 5 Hz. The results show that plasma shield lasertripsy is as effective as direct lasertripsy for fragmenting gallstones, struvite and calcium oxalate dihydrate calculi, is potentially safer, and can fragment cystine calculi which the pulsed dye laser applied directly cannot.

  7. Reflectance confocal microscopy-guided laser ablation of basal cell carcinomas: initial in vivo results

    NASA Astrophysics Data System (ADS)

    Sierra, Heidy; Cordova, Miguel; Yelamos, Oriol; Chen, Chih-Shan Jason; Rajadhyaksha, Milind

    2017-02-01

    Laser ablation offers a procedure for precise, fast and minimally invasive removal of superficial and early nodular basal cell carcinomas (BCCs). However, the lack of histopathological confirmation has been a limitation toward widespread use in the clinic. A reflectance confocal microscopy (RCM) imaging-guided laser ablation approach offers cellular-level histopathology-like feedback directly on the patient, which may guide and help improve the efficacy of this procedure. We performed an initial study on 44 BCCs on 21 patients in vivo (based in an ex vivo bench-top study reported in our earlier papers), using a pulsed erbium: ytterbium aluminum garnet laser and a contrast agent (aluminum chloride). Initial 10 lesions, the RCM imaging-guided detection of either presence of residual tumor or complete clearance was immediately confirmed with histopathology. Additionally, 34 BCCs on 15 patients were treated with RCM imaging-guided laser ablation, and the clearance of tumor is currently being monitored with follow-up imaging (i. e., no histopathology) at 3, 6 and 18 months. Thus far, the imaging resolution appears to be sufficient and consistent for monitoring efficacy in the wound, both immediately post-ablation and subsequently during recovery. The efficacy appears to be promising. However, further investigation and optimization to image over the entire wound (without missing any areas) need to be investigated.

  8. Distributive justice and global health: a call for a global corporate tax.

    PubMed

    Blum, J D

    2007-06-01

    Significant efforts have been directed toward addressing the financial needs of the developing world for assistance with public health and related development problems. Both public and private organizations have made considerable economic contributions to assist with immediate and long term health challenges, and there is growing international support for programs of national debit relief. Still, there is a need for additional resources to combat international health problems, which go beyond largesse. This paper calls for the creation of a legally rooted, global tax as a mechanism for consistent long term funding. Specifically, the paper proposes engagement of the World Trade Organization as a vehicle to sponsor a global tax on multinational corporations who have benefited most from the international trading scheme.

  9. Using Financial Ratios to Select Companies for Tax Auditing: A Preliminary Study

    NASA Astrophysics Data System (ADS)

    Marghescu, Dorina; Kallio, Minna; Back, Barbro

    Tax auditing procedures include an investigation of the accounting records of a company and of other sources of information in order to assess whether the taxation has been based on correct and complete information. When there are found discrepancies between the accounting information and the real situation, the taxation should be corrected so that the eventual tax defaults are assessed and debited. The paper analyzes to what extent the financial performance of a company can be used as an indicator of tax defaults. We focus on one type of tax, namely employer's contribution, and four financial ratios. We evaluate the model in a study of Finnish companies by using a binomial logistic regression analysis. The study is exploratory and at a preliminary stage.

  10. Investigation of return photons from sodium laser beacon excited by a 40-watt facility-class pulsed laser for adaptive optical telescope applications.

    PubMed

    Bian, Qi; Bo, Yong; Zuo, Junwei; Li, Min; Dong, Ruoxi; Deng, Keran; Zhang, Dingwen; He, Liping; Zong, Qingshuang; Cui, Dafu; Peng, Qinjun; Chen, Hongbin; Xu, Zuyan

    2018-06-15

    The brightness of the artificial beacon is one critical performance parameter for adaptive optics. Here, a 40-watt level narrow-linewidth microsecond pulsed yellow laser is produced at 589 nm with a high repetition frequency of 600 Hz and a pulse duration of 120 μs. An experiment to project the pulse beam up to the sky and measure the fluorescence photon returns of the Na atoms has been held on the 1.8-meter telescope in Lijiang observatory. During the sky test, a laser guide star (LGS) spot is firstly observed with Rayleigh scattering elimination by means of a gateable pulse format. And, the central wavelength of the laser could be accurately locked to be 589.1584 nm with a linewidth of ~0.34 GHz to match that of sodium-D 2a line. Optical pumping with circularly polarized light has also been used to increase the brightness of sodium LGS. In order to maximize the return flux, sodium D 2b repumping option is done by an electro-optic modulator with the optimum D 2a -D 2b frequency offset. As a result, a bright sodium LGS with the return flux of 1610 photons/cm 2 /s is achieved, corresponding to ~47 photons/cm 2 /s/W of emitted laser power, which represents a significant improvement in terms of brightness reported ever.

  11. Effective Dose of CT- and Fluoroscopy-Guided Perineural/Epidural Injections of the Lumbar Spine: A Comparative Study

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Schmid, Gebhard; Schmitz, Alexander; Borchardt, Dieter

    The objective of this study was to compare the effective radiation dose of perineural and epidural injections of the lumbar spine under computed tomography (CT) or fluoroscopic guidance with respect to dose-reduced protocols. We assessed the radiation dose with an Alderson Rando phantom at the lumbar segment L4/5 using 29 thermoluminescence dosimeters. Based on our clinical experience, 4-10 CT scans and 1-min fluoroscopy are appropriate. Effective doses were calculated for CT for a routine lumbar spine protocol and for maximum dose reduction; as well as for fluoroscopy in a continuous and a pulsed mode (3-15 pulses/s). Effective doses under CTmore » guidance were 1.51 mSv for 4 scans and 3.53 mSv for 10 scans using a standard protocol and 0.22 mSv and 0.43 mSv for the low-dose protocol. In continuous mode, the effective doses ranged from 0.43 to 1.25 mSv for 1-3 min of fluoroscopy. Using 1 min of pulsed fluoroscopy, the effective dose was less than 0.1 mSv for 3 pulses/s. A consequent low-dose CT protocol reduces the effective dose compared to a standard lumbar spine protocol by more than 85%. The latter dose might be expected when applying about 1 min of continuous fluoroscopy for guidance. A pulsed mode further reduces the effective dose of fluoroscopy by 80-90%.« less

  12. Narrow-linewidth, quasi-continuous-wave ASE source based on a multiple-pass Nd:YAG zigzag slab amplifier configuration.

    PubMed

    Chen, Xiaoming; Lu, Yanhua; Hu, Hao; Tong, Lixin; Zhang, Lei; Yu, Yi; Wang, Juntao; Ren, Huaijin; Xu, Liu

    2018-03-05

    We present investigations into a narrow-linewidth, quasi-continuous-wave pulsed all-solid-state amplified spontaneous emission (ASE) source by use of a novel multiple-pass zigzag slab amplifier. The SE fluorescence emitted from a Nd:YAG slab active medium acts as the seed and is amplified back and forth 8 times through the same slab. Thanks to the angular multiplexing nature of the zigzag slab, high-intensity 1064-nm ASE output can be produced without unwanted self-lasing in this configuration. Experimentally, the output energy, optical conversion efficiency, pulse dynamics, spectral property, and beam quality of the ASE source are studied when the Nd:YAG slab end-pumped by two high-brightness laser diode arrays. The maximum single pulse energy of 347 mJ is generated with an optical efficiency of ~5.9% and a beam quality of 3.5/17 in the thickness/width direction of the slab. As expected, smooth pulses without relaxing spikes and continuous spectra are achieved. Moreover, the spectral width of the ASE source narrows versus the pump energy, getting a 3-dB linewidth of as narrow as 20 pm (i.e. 5.3 GHz). Via the sum frequency generation, high-intensity, smooth-pulse, and narrow-linewidth ASE sources are preferred for solving the major problem of saturation of the mesospheric sodium atoms and can create a much brighter sodium guide star to meet the needs of adaptive imaging applications in astronomy.

  13. A quantum dynamics study of the benzopyran ring opening guided by laser pulses

    NASA Astrophysics Data System (ADS)

    Saab, Mohamad; Doriol, Loïc Joubert; Lasorne, Benjamin; Guérin, Stéphane; Gatti, Fabien

    2014-10-01

    The ring-opening photoisomerization of benzopyran, which occurs via a photochemical route involving a conical intersection, has been studied with quantum dynamics calculations using the multi-configuration time-dependent Hartree method (MCTDH). We introduce a mechanistic strategy to control the conversion of benzopyran to merocyanine with laser pulses. We use a six-dimensional model developed in a previous work for the potential energy surfaces (PES) based on an extension of the vibronic-coupling Hamiltonian model (diabatization method by ansatz), which depends on the most active degrees of freedom. The main objective of these quantum dynamics simulations is to provide a set of strategies that could help experimentalists to control the photoreactivity vs. photostability ratio (selectivity). In this work we present: (i) a pump-dump technique used to control the photostability, (ii) a two-step strategy to enhance the reactivity of the system: first, a pure vibrational excitation in the electronic ground state that prepares the system and, second, an ultraviolet excitation that brings the system to the first adiabatic electronic state; (iii) finally the effect of a non-resonant pulse (Stark effect) on the dynamics.

  14. Charting the functional relevance of Broca's area for visual word recognition and picture naming in Dutch using fMRI-guided TMS.

    PubMed

    Wheat, Katherine L; Cornelissen, Piers L; Sack, Alexander T; Schuhmann, Teresa; Goebel, Rainer; Blomert, Leo

    2013-05-01

    Magnetoencephalography (MEG) has shown pseudohomophone priming effects at Broca's area (specifically pars opercularis of left inferior frontal gyrus and precentral gyrus; LIFGpo/PCG) within ∼100ms of viewing a word. This is consistent with Broca's area involvement in fast phonological access during visual word recognition. Here we used online transcranial magnetic stimulation (TMS) to investigate whether LIFGpo/PCG is necessary for (not just correlated with) visual word recognition by ∼100ms. Pulses were delivered to individually fMRI-defined LIFGpo/PCG in Dutch speakers 75-500ms after stimulus onset during reading and picture naming. Reading and picture naming reactions times were significantly slower following pulses at 225-300ms. Contrary to predictions, there was no disruption to reading for pulses before 225ms. This does not provide evidence in favour of a functional role for LIFGpo/PCG in reading before 225ms in this case, but does extend previous findings in picture stimuli to written Dutch words. Copyright © 2012 Elsevier Inc. All rights reserved.

  15. Simulation of a suite of generic long-pulse neutron instruments to optimize the time structure of the European Spallation Source.

    PubMed

    Lefmann, Kim; Klenø, Kaspar H; Birk, Jonas Okkels; Hansen, Britt R; Holm, Sonja L; Knudsen, Erik; Lieutenant, Klaus; von Moos, Lars; Sales, Morten; Willendrup, Peter K; Andersen, Ken H

    2013-05-01

    We here describe the result of simulations of 15 generic neutron instruments for the long-pulsed European Spallation Source. All instruments have been simulated for 20 different settings of the source time structure, corresponding to pulse lengths between 1 ms and 2 ms; and repetition frequencies between 10 Hz and 25 Hz. The relative change in performance with time structure is given for each instrument, and an unweighted average is calculated. The performance of the instrument suite is proportional to (a) the peak flux and (b) the duty cycle to a power of approximately 0.3. This information is an important input to determining the best accelerator parameters. In addition, we find that in our simple guide systems, most neutrons reaching the sample originate from the central 3-5 cm of the moderator. This result can be used as an input in later optimization of the moderator design. We discuss the relevance and validity of defining a single figure-of-merit for a full facility and compare with evaluations of the individual instrument classes.

  16. Studies in fiber guided excimer laser surgery for cutting and drilling bone and meniscus.

    PubMed

    Dressel, M; Jahn, R; Neu, W; Jungbluth, K H

    1991-01-01

    Our experiments on transmitting high-power excimer laser pulses through optical fibers and our investigations on excimer laser ablation of hard tissue show the feasibility of using the excimer laser as an additional instrument in general and accident surgery involving minimal invasive surgery. By combining XeCl-excimer lasers and tapered fused silica fibers we obtained output fluences up to 32 J/cm2 and ablation rates of 3 microns/pulse of hard tissue. This enables us to cut bone and cartilage in a period of time which is suitable for clinical operations. Various experiments were carried out on cadavers in order to optimize the parameters of the excimer laser and fibers: e.g., wavelength, pulse duration, energy, repetition rate, fiber core diameter. The surfaces of the cut tissue are comparable to cuts with conventional instruments. No carbonisation was observed. The temperature increase is below 40 degrees C in the tissue surrounding the laser spot. The healing rate of an excimer laser cut is not slower than mechanical treatments; the quality is comparable.

  17. Pulse-parameter dependence of nuclear ``attosecond time delays''

    NASA Astrophysics Data System (ADS)

    Armstrong, Greg; Ursrey, D.; Hernandez, J. V.; Anis, F.; Severt, T.; Zohrabi, M.; Berry, Ben; Feizollah, Peyman; Jochim, Bethany; Kanaka Raju, P.; McKenna, J.; Gaire, B.; Carnes, K. D.; Ben-Itzhak, I.; Esry, B. D.

    2017-04-01

    One of the main goals of strong-field photodissociation is the control of chemical reactions. Recent experiments have successfully controlled the spatial asymmetry in D2+using two-color interferometry. These experiments achieved vibrational resolution, and so were able to determine the spatial asymmetry of a number of vibrational states as a function of two-color delay. The relative phase in the delay-dependent spatial asymmetry obtained in these experiments may be used to define a time delay in dissociation from adjacent vibrational states - a technique used previously to produce relative time delays in atomic ionization from the photoelectron spectrum. Further two-color measurements in this direction are being planned. As a guide to these experiments, we aim to determine theoretically the dependence of such delays on laser intensity, pulse length, and pulse shape. We also identify the parameters that maximize the contrast in the delay-dependent spatial asymmetry. This work is supported by the Chemical Sciences, Geosciences, and Biosciences Division, Office of Basic Energy Sciences, Office of Science, U. S. Department of Energy under Contract No. DE-FG02-86ER13191.

  18. The cochlear size of bats and rodents derived from MRI images and histology.

    PubMed

    Hsiao, Chun Jen; Jen, Philip Hung-Sun; Wu, Chung Hsin

    2015-05-27

    From the evolutionary perspective, the ear of each animal species is built for effective processing of the biologically relevant signals used for communication and acoustically guided orientation. Because the sound pulses used by echolocating bats for orientation and rodents for communication are quite different, the basic design of the mammalian auditory system commonly shared by echolocating bats must be specialized in some manner to effectively process their species-specific sounds. The present study examines the difference in the cochlea of these animal species using MRI images and histological techniques. We report here that, although all these animal species share a similar cochlear structure, they vary in their cochlear size and turns. Bats using constant frequency-frequency-modulated pulses (CF-FM bats) and frequency-modulated pulses (FM bats) for echolocation have a larger cochlear size and more cochlear turns than rodents (mice and rats). However, CF-FM bats have the largest cochlear size and most cochlear turns. This difference in cochlear size and turns of these animal species is discussed in relation to their biologically relevant sounds and acoustic behavior.

  19. Thermal Investigation of Interaction between High-power CW-laser Radiation and a Water-jet

    NASA Astrophysics Data System (ADS)

    Brecher, Christian; Janssen, Henning; Eckert, Markus; Schmidt, Florian

    The technology of a water guided laser beam has been industrially established for micro machining. Pulsed laser radiation is guided via a water jet (diameter: 25-250 μm) using total internal reflection. Due to the cylindrical jet shape the depth of field increases to above 50 mm, enabling parallel kerfs compared to conventional laser systems. However higher material thicknesses and macro geometries cannot be machined economically viable due to low average laser powers. Fraunhofer IPT has successfully combined a high-power continuous-wave (CW) fiber laser (6 kW) and water jet technology. The main challenge of guiding high-power laser radiation in water is the energy transferred to the jet by absorption, decreasing its stability. A model of laser water interaction in the water jet has been developed and validated experimentally. Based on the results an upscaling of system technology to 30 kW is discussed, enabling a high potential in cutting challenging materials at high qualities and high speeds.

  20. Mach-Zehnder atom interferometer inside an optical fiber

    NASA Astrophysics Data System (ADS)

    Xin, Mingjie; Leong, Wuiseng; Chen, Zilong; Lan, Shau-Yu

    2017-04-01

    Precision measurement with light-pulse grating atom interferometry in free space have been used in the study of fundamental physics and applications in inertial sensing. Recent development of photonic band-gap fibers allows light for traveling in hollow region while preserving its fundamental Gaussian mode. The fibers could provide a very promising platform to transfer cold atoms. Optically guided matter waves inside a hollow-core photonic band-gap fiber can mitigate diffraction limit problem and has the potential to bring research in the field of atomic sensing and precision measurement to the next level of compactness and accuracy. Here, we will show our experimental progress towards an atom interferometer in optical fibers. We designed an atom trapping scheme inside a hollow-core photonic band-gap fiber to create an optical guided matter waves system, and studied the coherence properties of Rubidium atoms in this optical guided system. We also demonstrate a Mach-Zehnder atom interferometer in the optical waveguide. This interferometer is promising for precision measurements and designs of mobile atomic sensors.

Top