A New Classification Scheme for For-Profit Institutions

ERIC Educational Resources Information Center

Institute for Higher Education Policy, 2012

2012-01-01

For-profit institutions are more visible today among policymakers, researchers, and investors, due in large part to the sharp rise in the number of students attending them over the last decade. From 2000 to 2009, enrollment in the for-profit sector tripled while enrollment in the public and not-for-profit sectors increased by less than 25 percent.…

Strategies and Policies for Basic Education in Cambodia: Historical Perspectives

ERIC Educational Resources Information Center

Dy, Sideth S.

2004-01-01

This article examines the process of development and change in the state of education in Cambodia over four decades preceding the 1990 Jomtien World Conference on Education for All. The author argues that during the 1950s and 1960s, efforts to enhance basic education opportunities for all Cambodians were largely unsuccessful due to the lack of…

The Hub and the Spokes: Foundations, Intermediary Organizations, Incentivist Reforms, and the Politics of Research Evidence

ERIC Educational Resources Information Center

Scott, Janelle; Jabbar, Huriya

2014-01-01

The rise in the influence of and spending by educational philanthropists and foundations over the past two decades, especially in the area of market-based reforms, such as charter schools, vouchers, and merit pay, is evident across the United States. Largely due to philanthropic investments, relatively new educational intermediary organizations…

Spring phenology at different altitudes is becoming more uniform under global warming in Europe.

PubMed

Chen, Lei; Huang, Jian-Guo; Ma, Qianqian; Hänninen, Heikki; Rossi, Sergio; Piao, Shilong; Bergeron, Yves

2018-04-26

Under current global warming, high-elevation regions are expected to experience faster warming than low-elevation regions. However, due to the lack of studies based on long-term large-scale data, the relationship between tree spring phenology and the elevation-dependent warming is unclear. Using 652k records of leaf unfolding of five temperate tree species monitored during 1951-2013 in situ in Europe, we discovered a nonlinear trend in the altitudinal sensitivity (S A , shifted days per 100 m in altitude) in spring phenology. A delayed leaf unfolding (2.7 ± 0.6 days per decade) was observed at high elevations possibly due to decreased spring forcing between 1951 and 1980. The delayed leaf unfolding at high-elevation regions was companied by a simultaneous advancing of leaf unfolding at low elevations. These divergent trends contributed to a significant increase in the S A (0.36 ± 0.07 days 100/m per decade) during 1951-1980. Since 1980, the S A started to decline with a rate of -0.32 ± 0.07 days 100/m per decade, possibly due to reduced chilling at low elevations and improved efficiency of spring forcing in advancing the leaf unfolding at high elevations, the latter being caused by increased chilling. Our results suggest that due to both different temperature changes at the different altitudes, and the different tree responses to these changes, the tree phenology has shifted at different rates leading to a more uniform phenology at different altitudes during recent decades. © 2018 John Wiley & Sons Ltd.

UV controlling factors and trends derived from the ground-based measurements taken at Belsk, Poland, 1976-1994

NASA Astrophysics Data System (ADS)

KrzyśCin, Janusz W.

1996-07-01

Monthly means of UV erythemal dose at ground level from the Robertson-Berger (RB) sunburn meter (1976-1992) and the UV-Biometer model 501 MED meter (1993-1994) located at Belsk (21°E, 52°N), Poland, are examined. The monthly means are calculated from all-sky daily means of UV erythemal dose. Ancillary measurements of column ozone (by Dobson spectrophotometer), sunshine duration (by Campbell-Stokes heliograph), and total (sun and sky) radiation (by a pyranometer) are considered to explain variations in the UV data. A multiple regression model is proposed to study trends in the UV data. The model accounts for the UV erythemal dose changes induced by total ozone, sunshine duration (surrogate for cloud cover variations), or total solar radiation (surrogate for combined cloud cover and atmospheric turbidity impact on the UV radiation), trends due to instrument drift, step changes in the data, and serial correlations. A strong relationship between monthly all-sky UV erythemal dose changes and total ozone (and total solar radiation) is found. Calculations show that an erythemal radiative amplification factor (RAF) due to ozone under all skies is close to its clear-sky value (about 1). However, the model gives evidence that the RAF due to ozone is smaller for cloudier (and/or more turbid) atmospheres than long-term reference. Total solar radiation change of 1% is associated with a change of 0.7% in the UV erythemal dose. Modeled trends in the Belsk's UV data, inferred from the model using ozone and total solar radiation as the UV forcing factors, are 2.3% ± 0.4% (1σ) per decade in the period 1976-1994. The large increase in the UV erythemal dose, of the order of 4% per decade due to ozone depletion (-3.2% per decade), is partially compensated by a decreasing tendency (-2.8% per decade) in total solar radiation. The model estimates the trend in the UV data of the order of 0.1% per decade (not statistically significant) due to superposition of the instrument drift and long-term effects related to other UV influencing factors (not parameterized by the model).

Anthropogenic hydrological cycle disturbance at a regional scale: State-wide evapotranspiration trends (1979-2015) across Nebraska, USA

NASA Astrophysics Data System (ADS)

Szilagyi, Jozsef

2018-02-01

Trends in monthly evapotranspiration (ET) rates across Nebraska, the most intensely irrigated state within the US, were calculated by the calibration-free version of the nonlinear complementary relationship of evaporation over the 1979-2015 period utilizing North American Regional Reanalysis (NARR) net radiation, 10-m wind velocity, as well as Parameter Regression Independent Slope Model (PRISM) air- and dew-point temperature data. State-averaged modeled ET rates rose by 5.5 mm decade-1 due to the presence of wide-spread large-scale irrigation projects in accordance with a 2.4 mm decade-1 increase in PRISM precipitation (P) and a simultaneous -2.8 mm decade-1 drop in United States Geological Survey's state-averaged annual streamflow rates, raising the state-wide ET to P ratio from 0.89 to 0.91 over the modeled time-period. ET rates over irrigated crops increased by 7 mm decade-1 despite a -4.4 mm decade-1 drop in precipitation rates. A similar increase in ET rates (6 mm decade-1) required 8.1 mm decade-1 increase in precipitation rates across the non-irrigated Sand Hills of Nebraska. Published NARR ET rates are unable to pick up this unusual regional trend. Since an increase in precipitation rates should normally decrease the ET ratio, as predicted by the Budyko curve, this study yields evidence on how dramatically sustained large-scale irrigation can alter the regional hydrologic cycle not only through a) trivially depleting streamflow rates and/or lowering groundwater table levels; b) suppressing precipitation locally (while enhancing it a long distance downwind), but also; c) reversing the trajectory of the regional ET ratio under generally increasing trends of precipitation.

Recent advances in research on the aeolian geomorphology of China's Kumtagh Sand Sea

NASA Astrophysics Data System (ADS)

Dong, Z.; Lv, P.

2014-02-01

The Kumtagh Sand Sea in the hyper-arid region of northwestern China remained largely unexplored until the last decade. It deserves study due to its significance in understanding the evolution of the arid environments in northwestern China, and even central Asia. Aeolian geomorphology in the sand sea has received unprecedented study in the last decade. Encouraging advances have been made in types of aeolian landforms, geological outlines, wind systems, the formation of aeolian landforms, several unique aeolian landforms, aeolian geomorphic regionalization, aeolian geomorphological heritages and tourism development, and aeolian sand hazards and their control. These advances expand our knowledge of aeolian geomorphology.

Carbon monoxide (CO) emissions and its tropospheric variability over Pakistan using satellite-sensed data

NASA Astrophysics Data System (ADS)

ul-Haq, Zia; Rana, Asim Daud; Ali, Muhammad; Mahmood, Khalid; Tariq, Salman; Qayyum, Zarmina

2015-08-01

This study presents major anthropogenic sources of carbon monoxide (CO) in Pakistan and discusses the spatio-temporal variability of tropospheric CO over Pakistan and neighboring regions of Afghanistan, India and Iran for a period from 2003 to 2012 using satellite-sensed (AIRS/AMSU) data. The results show a large spatio-temporal variability of CO over the study region mostly associated with anthropogenic activities such as crop residue burning, vehicular transport, and electricity and energy generation, and local meteorology. The annual mean value of tropospheric CO is observed to be 115 ± 2 ppbv that remains almost steady during the study period with decadal increase of only 2%. Due to more anthropogenic emissions of CO and its transport, the eastern zone shows a higher average value of 122 ± 2 ppbv with 2.7% decadal increase than the western zone (111 ± 3 ppbv with 1.4% decadal increase). Elevated concentrations of CO have been observed over the Indo-Gangetic Basin, Lahore, Karachi, and Delhi. During the study period large fluctuations in CO mean monthly values are found ranging from 99 ppbv to 131 ppbv. The fact that, in spite of a large increase in the CO emissions from 2003 to 2012, its average concentration remains almost stable indicates that a large scale regional transport contributes substantially to the tropospheric CO. Carbon monoxide concentrations exhibit a strong seasonal pattern with maximum amplitude in spring and minimum in autumn. July is found to have the highest decadal increasing trend of 13% followed by August at 8%, whereas May has the highest decreasing trend of -8% followed by November at -4.4%.

Impacts of Global Change on Water Resources in Dryland East Asia

Treesearch

Ge Sun; Xiaoming Feng; Jingfeng Xiao; Alex Shiklomanov; Shengping Wang; Zhiqiang Zhang; Nan Lu; Shuai Wang; Liding Chen; Bojie Fu; Yaning Chen; Jiquan Chen

2013-01-01

The vast Dryland East Asia (DEA) area consists of several large geographic regions including the Qinghai-Tibet Plateau, Loess Plateau, and Mongolia Plateau. T he region is of great importance to the functioning of the earth system under a changing climate. In the past three decades, due to the unprecedented land use/land cover change, urbanization, industrialization...

A New Classification Scheme for For-Profit Institutions. Fact Sheet

ERIC Educational Resources Information Center

Institute for Higher Education Policy, 2012

2012-01-01

For-profit institutions are more visible today among policymakers, researchers, and investors, due in large part to the sharp rise in the number of students attending them over the last decade. From 2000 to 2009, enrollment in the for-profit sector tripled while enrollment in the public and not-for-profit sectors increased by less than 25 percent.…

Dreams and Opportunities: Immigrant Families and Iowa's Future. Iowa Kid's Count Special Report

ERIC Educational Resources Information Center

Wright, Michelle Stover

2010-01-01

The fact that there has been population growth in Iowa at all (about 100,000 growth per decade over the last 50 years) is due in large measure to an increased level of immigration into the state. This immigration has helped to stabilize Iowa's population and workforce. Immigrants bring diverse experiences and backgrounds with them. This report…

Estimating How Often Mass Extinctions Due to Impacts Occur on the Earth

NASA Technical Reports Server (NTRS)

Buratti, Bonnie J.

2013-01-01

This hands-on, inquiry based activity has been taught at JPL's summer workshop "Teachers Touch the Sky" for the past two decades. Students act as mini-investigators as they gather and analyze data to estimate how often an impact large enough to cause a mass extinction occurs on the Earth. Large craters are counted on the Moon, and this number is extrapolated to the size of the Earth. Given the age of the Solar System, the students can then estimate how often large impacts occur on the Earth. This activity is based on an idea by Dr. David Morrison, NASA Ames Research Center.

Age-associated changes in cardiovascular structure and function: a fertile milieu for future disease

PubMed Central

Strait, James

2015-01-01

Important changes occur in the cardiovascular system with advancing age, even in apparently healthy individuals. Thickening and stiffening of the large arteries develop due to collagen and calcium deposition and loss of elastic fibers in the medial layer. These arterial changes cause systolic blood pressure to rise with age, while diastolic blood pressure generally declines after the sixth decade. In the left ventricle, modest concentric wall thickening occurs due to cellular hypertrophy, but cavity size does not change. Although left ventricular systolic function is preserved across the age span, early diastolic filling rate declines 30–50% between the third and ninth decades. Conversely, an age-associated increase in late diastolic filling due to atrial contraction preserves end-diastolic volume. Aerobic exercise capacity declines approximately 10% per decade in cross-sectional studies; in longitudinal studies, however, this decline is accelerated in the elderly. Reductions in peak heart rate and peripheral oxygen utilization but not stroke volume appear to mediate the age-associated decline in aerobic capacity. Deficits in both cardiac b-adrenergic receptor density and in the efficiency of postsynaptic b-adrenergic signaling contribute significantly to the reduced cardiovascular performance during exercise in older adults. Although these cardiovascular aging changes are considered “normative”, they lower the threshold for the development of cardiovascular disease, which affects the majority of older adults. PMID:21809160

The Federal Budget: Current and Upcoming Issues

DTIC Science & Technology

2008-12-10

the FY2009 and FY2010 federal budgets. Federal spending tied to means- tested social programs has been increasing due to rising unemployment, while...significant financial interventions in an attempt to alleviate economic recession. The ultimate costs of federal responses to this turmoil will...to the economic slowdown with an array of policy responses unprecedented in recent decades. Many economists believe a large fiscal stimulus is in

What's behind the Good News: The Decline in Teen Pregnancy Rates during the 1990s.

ERIC Educational Resources Information Center

Flanigan, Christine

Noting that rates of teen pregnancies and births have declined over the past decade, this analysis examined how much of the progress is due to fewer teens having sex and how much to lower rates of pregnancy among sexually active teens. The analysis drew on data from the federal government's National Survey of Family Growth (NSFG), a large,…

On the Development and Use of Large Chemical Similarity Networks, Informatics Best Practices and Novel Chemical Descriptors towards Materials Quantitative Structure Property Relationships

ERIC Educational Resources Information Center

Krein, Michael

2011-01-01

After decades of development and use in a variety of application areas, Quantitative Structure Property Relationships (QSPRs) and related descriptor-based statistical learning methods have achieved a level of infamy due to their misuse. The field is rife with past examples of overtrained models, overoptimistic performance assessment, and outright…

A Case Study of Factors That Influenced the Attrition or Retention of Two First-Year Special Education Teachers

ERIC Educational Resources Information Center

Grant, Marquis C.

2017-01-01

The issue of attrition and retention has been a chronic problem in the field of education for decades. School districts across the United States are experiencing shortages of qualified special education teachers largely due to high turnover rates, with many of these teachers electing not to return after their first year of teaching. In fact,…

Two Decades of Negative Thermal Expansion Research: Where Do We Stand?

PubMed Central

Lind, Cora

2012-01-01

Negative thermal expansion (NTE) materials have become a rapidly growing area of research over the past two decades. The initial discovery of materials displaying NTE over a large temperature range, combined with elucidation of the mechanism behind this unusual property, was followed by predictions that these materials will find use in various applications through controlled thermal expansion composites. While some patents have been filed and devices built, a number of obstacles have prevented the widespread implementation of NTE materials to date. This paper reviews NTE materials that contract due to transverse atomic vibrations, their potential for use in controlled thermal expansion composites, and known problems that could interfere with such applications. PMID:28817027

An 'Observational Large Ensemble' to compare observed and modeled temperature trend uncertainty due to internal variability.

NASA Astrophysics Data System (ADS)

Poppick, A. N.; McKinnon, K. A.; Dunn-Sigouin, E.; Deser, C.

2017-12-01

Initial condition climate model ensembles suggest that regional temperature trends can be highly variable on decadal timescales due to characteristics of internal climate variability. Accounting for trend uncertainty due to internal variability is therefore necessary to contextualize recent observed temperature changes. However, while the variability of trends in a climate model ensemble can be evaluated directly (as the spread across ensemble members), internal variability simulated by a climate model may be inconsistent with observations. Observation-based methods for assessing the role of internal variability on trend uncertainty are therefore required. Here, we use a statistical resampling approach to assess trend uncertainty due to internal variability in historical 50-year (1966-2015) winter near-surface air temperature trends over North America. We compare this estimate of trend uncertainty to simulated trend variability in the NCAR CESM1 Large Ensemble (LENS), finding that uncertainty in wintertime temperature trends over North America due to internal variability is largely overestimated by CESM1, on average by a factor of 32%. Our observation-based resampling approach is combined with the forced signal from LENS to produce an 'Observational Large Ensemble' (OLENS). The members of OLENS indicate a range of spatially coherent fields of temperature trends resulting from different sequences of internal variability consistent with observations. The smaller trend variability in OLENS suggests that uncertainty in the historical climate change signal in observations due to internal variability is less than suggested by LENS.

Uncertainties in Past and Future Global Water Availability

NASA Astrophysics Data System (ADS)

Sheffield, J.; Kam, J.

2014-12-01

Understanding how water availability changes on inter-annual to decadal time scales and how it may change in the future under climate change are a key part of understanding future stresses on water and food security. Historic evaluations of water availability on regional to global scales are generally based on large-scale model simulations with their associated uncertainties, in particular for long-term changes. Uncertainties are due to model errors and missing processes, parameter uncertainty, and errors in meteorological forcing data. Recent multi-model inter-comparisons and impact studies have highlighted large differences for past reconstructions, due to different simplifying assumptions in the models or the inclusion of physical processes such as CO2 fertilization. Modeling of direct anthropogenic factors such as water and land management also carry large uncertainties in their physical representation and from lack of socio-economic data. Furthermore, there is little understanding of the impact of uncertainties in the meteorological forcings that underpin these historic simulations. Similarly, future changes in water availability are highly uncertain due to climate model diversity, natural variability and scenario uncertainty, each of which dominates at different time scales. In particular, natural climate variability is expected to dominate any externally forced signal over the next several decades. We present results from multi-land surface model simulations of the historic global availability of water in the context of natural variability (droughts) and long-term changes (drying). The simulations take into account the impact of uncertainties in the meteorological forcings and the incorporation of water management in the form of reservoirs and irrigation. The results indicate that model uncertainty is important for short-term drought events, and forcing uncertainty is particularly important for long-term changes, especially uncertainty in precipitation due to reduced gauge density in recent years. We also discuss uncertainties in future projections from these models as driven by bias-corrected and downscaled CMIP5 climate projections, in the context of the balance between climate model robustness and climate model diversity.

From Assessment to Instruction: The Impact of Online Formative Assessment in Reading on Teachers' Planning and Instruction in the Middle School English Language Arts Classroom

ERIC Educational Resources Information Center

Hayes, Ann Milligan

2015-01-01

Over the last two decades, there has been renewed interest in formative assessment, in large part due to the increasing pressures and prevalence of "high stakes" summative assessments. As states try to meet the requirements of the No Child Left Behind law, teachers and administrators are realizing that formative assessment offers an…

A Review of Children's Rights Literature since the Adoption of the United Nations Convention on the Rights of the Child

ERIC Educational Resources Information Center

Reynaert, Didier; Bouverne-de-Bie, Maria; Vandevelde, Stijn

2009-01-01

Children's rights have become a significant field of study during the past decades, largely due to the adoption of the United Nations Convention on the Rights of the Child (UNCRC) in 1989. Today, scholarly work on children's rights is almost inconceivable without considering the Convention as the bearer of the children's rights debate. The goal of…

Escape of Hydrogen from the Exosphere of Mars

NASA Astrophysics Data System (ADS)

Bhattacharyya, Dolon; Clarke, John T.; Bertaux, Jean-Loup; Chaufray, Jean-Yves; Mayyasi-Matta, Majd A.

2016-10-01

After decades of exploration, the martian neutral hydrogen exosphere has remained largely uncharacterized even today. In my dissertation I have attempted to constrain the characteristics of the martian hydrogen exosphere using Hubble Space Telescope observations obtained during October-November 2007 and 2014. These observations reveal short-term seasonal changes exhibited by the martian hydrogen exosphere that are inconsistent with the diffusion-limited escape scenario. This seasonal behavior adds a new element towards backtracking the history of water loss from Mars. Modeling of the data also indicates the likely presence of a superthermal population of hydrogen created by non-thermal processes at Mars, another key element to understand the present-day escape. Exploration of the latitudinal symmetry of the martian exosphere indicates that it is symmetric above 2.5 martian radii and asymmetric below this altitude, which could be due to temperature differences between the day and night sides. Finally, the large uncertainties in determining the characteristics of the martian exosphere after decades of exploration is due to various assumptions about the intrinsic characteristics of the martian exosphere in the modeling process, degeneracy in the two modeling parameters temperature and density of the hydrogen atoms, unaccounted seasonal effects, and uncertainties introduced from spacecraft instrumentation as well as their viewing geometry.

When can ocean acidification impacts be detected from decadal alkalinity measurements?

NASA Astrophysics Data System (ADS)

Carter, B. R.; Frölicher, T. L.; Dunne, J. P.; Rodgers, K. B.; Slater, R. D.; Sarmiento, J. L.

2016-04-01

We use a large initial condition suite of simulations (30 runs) with an Earth system model to assess the detectability of biogeochemical impacts of ocean acidification (OA) on the marine alkalinity distribution from decadally repeated hydrographic measurements such as those produced by the Global Ship-Based Hydrographic Investigations Program (GO-SHIP). Detection of these impacts is complicated by alkalinity changes from variability and long-term trends in freshwater and organic matter cycling and ocean circulation. In our ensemble simulation, variability in freshwater cycling generates large changes in alkalinity that obscure the changes of interest and prevent the attribution of observed alkalinity redistribution to OA. These complications from freshwater cycling can be mostly avoided through salinity normalization of alkalinity. With the salinity-normalized alkalinity, modeled OA impacts are broadly detectable in the surface of the subtropical gyres by 2030. Discrepancies between this finding and the finding of an earlier analysis suggest that these estimates are strongly sensitive to the patterns of calcium carbonate export simulated by the model. OA impacts are detectable later in the subpolar and equatorial regions due to slower responses of alkalinity to OA in these regions and greater seasonal equatorial alkalinity variability. OA impacts are detectable later at depth despite lower variability due to smaller rates of change and consistent measurement uncertainty.

Cystic Fibrosis Related Liver Disease—Another Black Box in Hepatology

PubMed Central

Staufer, Katharina; Halilbasic, Emina; Trauner, Michael; Kazemi-Shirazi, Lili

2014-01-01

Due to improved medical care, life expectancy in patients with cystic fibrosis (CF) has veritably improved over the last decades. Importantly, cystic fibrosis related liver disease (CFLD) has become one of the leading causes of morbidity and mortality in CF patients. However, CFLD might be largely underdiagnosed and diagnostic criteria need to be refined. The underlying pathomechanisms are largely unknown, and treatment strategies with proven efficacy are lacking. This review focuses on current invasive and non-invasive diagnostic standards, the current knowledge on the pathophysiology of CFLD, treatment strategies, and possible future developments. PMID:25093717

Effects of energy drinks on the cardiovascular system

PubMed Central

Wassef, Bishoy; Kohansieh, Michelle; Makaryus, Amgad N

2017-01-01

Throughout the last decade, the use of energy drinks has been increasingly looked upon with caution as potentially dangerous due to their perceived strong concentration of caffeine aside from other substances such as taurine, guarana, and L-carnitine that are largely unknown to the general public. In addition, a large number of energy drink intoxications have been reported all over the world including cases of seizures and arrhythmias. In this paper, we focus on the effect of energy drinks on the cardiovascular system and whether the current ongoing call for the products’ sales and regulation of their contents should continue. PMID:29225735

Effects of energy drinks on the cardiovascular system.

PubMed

Wassef, Bishoy; Kohansieh, Michelle; Makaryus, Amgad N

2017-11-26

Throughout the last decade, the use of energy drinks has been increasingly looked upon with caution as potentially dangerous due to their perceived strong concentration of caffeine aside from other substances such as taurine, guarana, and L-carnitine that are largely unknown to the general public. In addition, a large number of energy drink intoxications have been reported all over the world including cases of seizures and arrhythmias. In this paper, we focus on the effect of energy drinks on the cardiovascular system and whether the current ongoing call for the products' sales and regulation of their contents should continue.

In-Situ Printing of Conductive Polylactic Acid (cPLA) Strain Sensors Embedded into Additively Manufactured Parts using Fused Deposition Modeling

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ouellette, Brittany Joy

Additive Manufacturing (AM) technology has been around for decades, but until recently, machines have been expensive, relatively large, and not available to most institutions. Increased technological advances in 3D printing and awareness throughout industry, universities, and even hobbyists has increased demand to substitute AM parts in place of traditionally manufactured (subtractive) designs; however, there is a large variability of part quality and mechanical behavior due to the inherent printing process, which must be understood before AM parts are used for load bearing and structural design.

The role of internal variability for decadal carbon uptake anomalies in the Southern Ocean

NASA Astrophysics Data System (ADS)

Spring, Aaron; Hi, Hongmei; Ilyina, Tatiana

2017-04-01

The Southern Ocean is a major sink for anthropogenic CO2 emissions and hence it plays an essential role in modulating global carbon cycle and climate change. Previous studies based on observations (e.g., Landschützer et al. 2015) show pronounced decadal variations of carbon uptake in the Southern Ocean in recent decades and this variability is largely driven by internal climate variability. However, due to limited ensemble size of simulations, the variability of this important ocean sink is still poorly assessed by the state-of-the-art earth system models (ESMs). To assess the internal variability of carbon sink in the Southern Ocean, we use a large ensemble of 100 member simulations based on the Max Planck Institute-ESM (MPI-ESM). The large ensemble of simulations is generated via perturbed initial conditions in the ocean and atmosphere. Each ensemble member includes a historical simulation from 1850 to 2005 with an extension until 2100 under Representative Concentration Pathway (RCP) 4.5 future projections. Here we use model simulations from 1980-2015 to compare with available observation-based dataset. We found several ensemble members showing decadal decreasing trends in the carbon sink, which are similar to the trend shown in observations. This result suggests that MPI-ESM large ensemble simulations are able to reproduce decadal variation of carbon sink in the Southern Ocean. Moreover, the decreasing trends of Southern Ocean carbon sink in MPI-ESM are mainly contributed by region between 50-60°S. To understand the internal variability of the air-sea carbon fluxes in the Southern Ocean, we further investigate the variability of underlying processes, such as physical climate variability and ocean biological processes. Our results indicate two main drivers for the decadal decreasing trend of carbon sink: i) Intensified winds enhance upwelling of old carbon-rich waters, this leads to increase of the ocean surface pCO2; ii) Primary production is reduced in area from 50-60°S, probably induced by reduced euphotic water column stability; therefore the biological drawdown of ocean surface pCO2 is weakened accordingly and hence the ocean is in favor of carbon outgassing. Landschützer, et al. (2015): The reinvigoration of the Southern Ocean carbon sink, Science, 349, 1221-1224.

Impacts of climate variability and change on crop yield in sub-Sahara Africa

NASA Astrophysics Data System (ADS)

Pan, S.; Zhang, J.; Yang, J.; Chen, G.; Xu, R.; Zhang, B.; Lou, Y.

2017-12-01

Much concern has been raised about the impacts of climate change and climate extremes on Africa's food security. The impact of climate change on Africa's agriculture is likely to be severe compared to other continents due to high rain-fed agricultural dependence, and limited ability to mitigate and adapt to climate change. In recent decades, warming in Africa is more pronounced and faster than the global average and this trend is likely to continue in the future. However, quantitative assessment on impacts of climate extremes and climate change on crop yield has not been well investigated yet. By using an improved agricultural module of the Dynamic Land Ecosystem Model (DLEM-AG2) driven by spatially-explicit information on land use, climate and other environmental changes, we have assessed impacts of historical climate variability and future climate change on food crop yield across the sub-Sahara Africa during1980-2016 and the rest of the 21st century (2017-2099). Our simulated results indicate that African crop yield in the past three decades shows an increasing trend primarily due to cropland expansion. However, crop yield shows substantially spatial and temporal variation due to inter-annual and inter-decadal climate variability and spatial heterogeneity of environmental drivers. Droughts have largely reduced crop yield in the most vulnerable regions of Sub-Sahara Africa. Future projections with DLEM-AG2 show that food crop production in Sub-Sahara Africa would be favored with limiting end-of-century warming to below 1.50 C.

CRIMALDDI: a co-ordinated, rational, and integrated effort to set logical priorities in anti-malarial drug discovery initiatives

PubMed Central

2010-01-01

Despite increasing efforts and support for anti-malarial drug R&D, globally anti-malarial drug discovery and development remains largely uncoordinated and fragmented. The current window of opportunity for large scale funding of R&D into malaria is likely to narrow in the coming decade due to a contraction in available resources caused by the current economic difficulties and new priorities (e.g. climate change). It is, therefore, essential that stakeholders are given well-articulated action plans and priorities to guide judgments on where resources can be best targeted. The CRIMALDDI Consortium (a European Union funded initiative) has been set up to develop, through a process of stakeholder and expert consultations, such priorities and recommendations to address them. It is hoped that the recommendations will help to guide the priorities of the European anti-malarial research as well as the wider global discovery agenda in the coming decade. PMID:20626844

Accelerating forest growth enhancement due to climate and atmospheric changes in British Colombia, Canada over 1956-2001.

PubMed

Wu, Chaoyang; Hember, Robbie A; Chen, Jing M; Kurz, Werner A; Price, David T; Boisvenue, Céline; Gonsamo, Alemu; Ju, Weimin

2014-03-25

Changes in climate and atmospheric CO2 and nitrogen (N) over the last several decades have induced significant effects on forest carbon (C) cycling. However, contributions of individual factors are largely unknown because of the lack of long observational data and the undifferentiating between intrinsic factors and external forces in current ecosystem models. Using over four decades (1956-2001) of forest inventory data at 3432 permanent samples in maritime and boreal regions of British Columbia (B.C.), Canada, growth enhancements were reconstructed and partitioned into contributions of climate, CO2 and N after removal of age effects. We found that climate change contributed a particularly large amount (over 70%) of the accumulated growth enhancement, while the remaining was attributed to CO2 and N, respectively. We suggest that climate warming is contributing a widespread growth enhancement in B.C.'s forests, but ecosystem models should consider CO2 and N fertilization effects to fully explain inventory-based observations.

Influence of high-latitude warming and land-use changes in the early 20th century northern Eurasian CO2 sink

NASA Astrophysics Data System (ADS)

Bastos, Ana; Peregon, Anna; Gani, Érico A.; Khudyaev, Sergey; Yue, Chao; Li, Wei; Gouveia, Célia M.; Ciais, Philippe

2018-06-01

While the global carbon budget (GCB) is relatively well constrained over the last decades of the 20th century [1], observations and reconstructions of atmospheric CO2 growth rate present large discrepancies during the earlier periods [2]. The large uncertainty in GCB has been attributed to the land biosphere, although it is not clear whether the gaps between observations and reconstructions are mainly because land-surface models (LSMs) underestimate inter-annual to decadal variability in natural ecosystems, or due to inaccuracies in land-use change reconstructions. As Eurasia encompasses about 15% of the terrestrial surface, 20% of the global soil organic carbon pool and constitutes a large CO2 sink, we evaluate the potential contribution of natural and human-driven processes to induce large anomalies in the biospheric CO2 fluxes in the early 20th century. We use an LSM specifically developed for high-latitudes, that correctly simulates Eurasian C-stocks and fluxes from observational records [3], in order to evaluate the sensitivity of the Eurasian sink to the strong high-latitude warming occurring between 1930 and 1950. We show that the LSM with improved high-latitude phenology, hydrology and soil processes, contrary to the group of LSMs in [2], is able to represent enhanced vegetation growth linked to boreal spring warming, consistent with tree-ring time-series [4]. By compiling a dataset of annual agricultural area in the Former Soviet Union that better reflects changes in cropland area linked with socio-economic fluctuations during the early 20th century, we show that land-abadonment during periods of crisis and war may result in reduced CO2 emissions from land-use change (44%–78% lower) detectable at decadal time-scales. Our study points to key processes that may need to be improved in LSMs and LUC datasets in order to better represent decadal variability in the land CO2 sink, and to better constrain the GCB during the pre-observational record.

Estimating Viscoelastic Deformation Due to Seasonal Loading

NASA Technical Reports Server (NTRS)

Sauber, Jeanne

2015-01-01

Scientists have been making summer-­-time geodetic measurements in south central Alaska for decades to estimate the rate at which a continental-­-ocean terrane is accreting to the North American continent. Southern Alaska has big earthquakes every century and large, rapidly changing glaciers. In the last decade, primarily as part of the EarthScope Plate Boundary Observatory project, continuous GPS measurements have recorded the response of sites such as the near-­-coastal geodetic site, AB35 to competing processes: uplift and movement to the northwest due to tectonic forces and the response of the solid Earth to seasonal and longer-­-term changes in the cryosphere (snow and ice) surrounding the site. Which process causes the largest displacements of the site? Figure 1 (Blewitt, Nevada Geodetic Lab, 2015) shows the Northward, Eastward, and Upward motion of AB35 between 2007 and 2015. The site is moving rapidly to the north and west reflecting the tectonic convergence of site toward interior Alaska but there is small wiggle on the North component reflecting seasonal displacements of the site associated with snow loading and unloading. However, the Up component, shows a large seasonal signal due to snow loading in the winter (down) and ice and snow melting in the warmer months (site goes up). Between 2007 and the present, the site position is slowly moving upward, due to tectonic forcing but probably associated with longer-­- term ice melting as well. We are using the CIG finite element modeling (FEM) program Pylith to estimate the surface displacements and stresses associated with seasonal loading changes (top figure and Figure 2 far right) for water year 2012, 2011.8 - 2012.8) and the longer-­-term retreat of the surrounding glaciers.

Ode to Healing Music in Health Care.

PubMed

Powell, Suzanne K

2016-01-01

Music therapy has been around since the 1940s when physicians notice a positive effect that music had on the soldiers with "shell shock" (now more commonly known as posttraumatic stress disorder). For decades, veterans were the primary patients worked with by music therapists. In the 1970s, the hospice movement started to enter the health care continuum, largely due to Dr Elisabeth Kübler-Ross, who advocated for home care and patient choice for the terminally ill. Two decades later, it became apparent that hospice patients could benefit from music. And currently, there are not enough people certified to work with music in hospice patients, veterans, or patients with dementia/Alzheimer's disease. No, music does not prolong life, but it does add life to the time left.

Tuberculous Pleurisy: An Update

PubMed Central

2014-01-01

Tuberculous pleurisy is the most common form of extrapulmonary tuberculosis in Korea. Tuberculous pleurisy presents a diagnostic and therapeutic problem due to the limitations of traditional diagnostic tools. There have been many clinical research works during the past decade. Recent studies have provided new insight into the tuberculous pleurisy, which have a large impact on clinical practice. This review is a general overview of tuberculous pleurisy with a focus on recent findings on the diagnosis and management. PMID:24851127

Experimental seismic behavior of a full-scale four-story soft-story wood-frame building with retrofits II: shake table test results

Treesearch

John W. van de Lindt; Pouria Bahmani; Gary Mochizuki; Steven E. Pryor; Mikhail Gershfeld; Jingjing Tian; Michael D. Symans; Douglas Rammer

2016-01-01

Soft-story wood-frame buildings have been recognized as a disaster preparedness problem for decades. The majority of these buildings were constructed from the 1920s to the 1960s and are prone to collapse during moderate to large earthquakes due to a characteristic deficiency in strength and stiffness in their first story. In order to propose and validate retrofit...

Modulated phase matching and high-order harmonic enhancement mediated by the carrier-envelope phase

DOE Office of Scientific and Technical Information (OSTI.GOV)

Faccio, Daniele; CNISM and Department of Physics and Mathematics, Universita dell'Insubria, Via Valleggio 11, I-22100 Como; Serrat, Carles

2010-01-15

The process of high-order harmonic generation in gases is numerically investigated in the presence of a few-cycle pulsed-Bessel-beam pump, featuring a periodic modulation in the peak intensity due to large carrier-envelope-phase mismatch. A two-decade enhancement in the conversion efficiency is observed and interpreted as the consequence of a mechanism known as a nonlinearly induced modulation in the phase mismatch.

Rapid EHR development and implementation using web and cloud-based architecture in a large home health and hospice organization.

PubMed

Weaver, Charlotte A; Teenier, Pamela

2014-01-01

Health care organizations have long been limited to a small number of major vendors in their selection of an electronic health record (EHR) system in the national and international marketplace. These major EHR vendors have in common base systems that are decades old, are built in antiquated programming languages, use outdated server architecture, and are based on inflexible data models [1,2]. The option to upgrade their technology to keep pace with the power of new web-based architecture, programming tools and cloud servers is not easily undertaken due to large client bases, development costs and risk [3]. This paper presents the decade-long efforts of a large national provider of home health and hospice care to select an EHR product, failing that to build their own and failing that initiative to go back into the market in 2012. The decade time delay had allowed new technologies and more nimble vendors to enter the market. Partnering with a new start-up company doing web and cloud based architecture for the home health and hospice market, made it possible to build, test and implement an operational and point of care system in 264 home health locations across 40 states and three time zones in the United States. This option of "starting over" with the new web and cloud technologies may be posing a next generation of new EHR vendors that retells the Blackberry replacement by iPhone story in healthcare.

Nuclear energy: Between global electricity demand, worldwide decarbonisation imperativeness, and planetary environmental implications.

PubMed

Prăvălie, Remus; Bandoc, Georgeta

2018-03-01

For decades, nuclear energy has been considered an important option for ensuring global energy security, and it has recently started being promoted as a solution for climate change mitigation. However, nuclear power remains highly controversial due to its associated risks - nuclear accidents and problematic radioactive waste management. This review aims to assess the viability of global nuclear energy economically (energy-wise), climatically and environmentally. To this end, the nuclear sector's energy- and climate-related advantages were explored alongside the downsides that mainly relate to radioactive pollution. Economically, it was found that nuclear energy is still an important power source in many countries around the world. Climatically, nuclear power is a low-carbon technology and can therefore be a viable option for the decarbonization of the world's major economies over the following decades, if coupled with other large-scale strategies such as renewable energies. These benefits are however outweighed by the radioactive danger associated to nuclear power plants, either in the context of the nuclear accidents that have already occurred or in that of the large amounts of long-lived nuclear waste that have been growing for decades and that represent a significant environmental and societal threat. Copyright © 2017 Elsevier Ltd. All rights reserved.

Geodetic mass balance of key glaciers across High Mountain Asia: a multi-decadal survey

NASA Astrophysics Data System (ADS)

Maurer, J. M.; Schaefer, J. M.; Rupper, S.; Corley, A. D.

2016-12-01

Glaciers in High Mountain Asia (HMA) supply seasonal meltwater for large populations, yet field observations are scarce and glacier sensitivities are poorly understood. In order to link complex atmospheric driving factors with heterogeneous glacier responses, detailed remote sensing observations of past changes in ice volume are needed. Here we compile a spatially and temporally extensive satellite-based remote sensing record to quantify multi-decadal geodetic mass balance of large mountain glaciers across key regions in HMA, including the Pamir, Himachal Pradesh, Uttarakhand, Nepal, Sikkim, and Bhutan regions. By utilizing declassified spy satellite imagery from the 1970's, ASTER scenes spanning 2000-present, and the ALOS global digital surface model, a methodologically homogenous assessment of regional and individual glacier responses to climate change over several decades is obtained. Although gaps due to low radiometric contrast result in significant uncertainties, the consistent approach across the HMA provides a useful comparison of relative geodetic changes between climatically diverse regions. Various patterns of ice loss are observed, including dynamic retreat of clean-ice glaciers and downwasting of debris-covered glaciers. In particular, we highlight the pronounced thinning and retreat of glaciers undergoing calving into proglacial lakes, which has important implications regarding ongoing and future ice loss of HMA glaciers.

Calibration of decadal ensemble predictions

NASA Astrophysics Data System (ADS)

Pasternack, Alexander; Rust, Henning W.; Bhend, Jonas; Liniger, Mark; Grieger, Jens; Müller, Wolfgang; Ulbrich, Uwe

2017-04-01

Decadal climate predictions are of great socio-economic interest due to the corresponding planning horizons of several political and economic decisions. Due to uncertainties of weather and climate, forecasts (e.g. due to initial condition uncertainty), they are issued in a probabilistic way. One issue frequently observed for probabilistic forecasts is that they tend to be not reliable, i.e. the forecasted probabilities are not consistent with the relative frequency of the associated observed events. Thus, these kind of forecasts need to be re-calibrated. While re-calibration methods for seasonal time scales are available and frequently applied, these methods still have to be adapted for decadal time scales and its characteristic problems like climate trend and lead time dependent bias. Regarding this, we propose a method to re-calibrate decadal ensemble predictions that takes the above mentioned characteristics into account. Finally, this method will be applied and validated to decadal forecasts from the MiKlip system (Germany's initiative for decadal prediction).

Identifying and Analyzing Preferences for the Next Decade of Astrophysics

NASA Astrophysics Data System (ADS)

Mesmer, Bryan; Weger, Kristin

2018-06-01

The Decadal Survey is conducted by the United States National Academies and is a summary of opinions from individuals in the Astronomy community, used to recommend the next decade of prioritized astrophysics missions and activities. From a systems engineering and psychology perspective, the Decadal Survey process is interesting due to the: large and diverse community being sampled, the diverse preferences, and the group interactions that result in a common voice. When preparing input to be reviewed in such a process, it is important to recognize and understand both individual factors, as well as group factors. By understanding these dynamics it is possible to better predict the likely outcome.This research looks to better understand the preferences of the Astronomy community as they relate to the coming decade. Preferences are the desires held by an individual. Along with beliefs and alternatives, preferences are one of three necessary elements to make a decision, according to normative decision analysis. Hence, by understanding preferences, and making assumptions on beliefs and available alternatives, one can determine what decision an individual ought to make through normative decision analysis. Due to the community focus of the Decadal Study, it is important to understand the interactions of individuals that results in a group outcome. This is where game theory is an effective tool, enabling the mathematical analysis of interacting individuals.Before any analysis is performed preferences must be captured and mathematically represented through value models, which is precisely what this research examines. This Iposter is associated with a questionnaire to better understand the preferences of individuals. The questionnaire will be promoted through the Iposter as well as by the authors at the conference. The questionnaire will attempt to gather data to enable the formation of value functions resulting in a better understanding of the community likings. The research is applicable to a wide range of similar community-driven recommendations, such as NSF proposal reviews.

Tallness versus shrinkage: do women shrink with age or grow taller with recent birth date?

PubMed

Davies, K M; Recker, R R; Stegman, M R; Heaney, R P

1991-10-01

This paper presents evidence that much of the high rate of age-related height loss in women reported in cross-sectional studies is actually a cohort effect rather than an aging effect. Data from a large cross-sectional study of healthy, white American women indicate that there has been a gain in peak adult height of 1.0 cm per decade for several decades from 1900 through 1965. Data from the HES, HANES I, and HANES II studies concur on this point. By contrast, data from a longitudinal study of 191 healthy white U.S. women show only a trivial rate of decline from peak adult height in the fifth and sixth decades of life. In an unselected population, some apparent height loss with age is probably due to disease processes, such as vertebral collapse. Caution is needed in using aging to interpret differences in height and in height-dependent variables, such as bone density, in cross-sectional studies.

Dynamic/Jitter Assessment of Multiple Potential HabEx Structural Designs

NASA Technical Reports Server (NTRS)

Knight, J. Brent; Stahl, H. Philip; Singleton, Andrew William; Hunt, Ronald A.; Therrell, Melissa F.; Caldwell, Mary Kathryn; Garcia, Jay Clarke

2017-01-01

The 2020 Decadal Survey in Astronomy and Astrophysics will assess candidate large missions to follow James Webb Space Telescope (JWST) and Wide Field Infrared Space Telescope (WFIRST). One candidate mission is the Habitable ExoPlanet Imaging Mission (HabEx). This presentation describes two HabEx structural designs and results from structural dynamic analyses performed to predict Primary Mirror (PM) Secondary Mirror (SM) Line of Site (LOS) stability (jitter) due to Reaction Wheel Assembly (RWA) vibrations.

Potential productivity benefits of float-zone versus Czochralski crystal growth

NASA Technical Reports Server (NTRS)

Abe, T.

1985-01-01

Efficient mass production of single-crystal silicon is necessary for the efficient silicon solar arrays needed in the coming decade. However, it is anticipated that there will be difficulty growing such volumes of crystals using conventional Czochralski (Cz) methods. While the productivity of single crystals might increase with a crystal diameter increase, there are two obstacles to the mass production of large diameter Czochralski crystals, the long production cycle due to slow growth rate and the high heat requirements of the furnaces. Also counterproductive would be the large resistivity gradient along the growth direction of the crystals due to impurity concentration. Comparison between Float zone (FZ) and Cz crystal growth on the basis of a crystal 150 mm in diameter is on an order of two to four times in favor of the FZ method. This advantage results from high growth rates and steady-state growth while maintaining a dislocation-free condition and impurity segregation.

Global Warming Estimation from MSU

NASA Technical Reports Server (NTRS)

Prabhakara, C.; Iacovazzi, Robert; Yoo, Jung-Moon

1998-01-01

Microwave Sounding Unit (MSU) radiometer observations in Ch 2 (53.74 GHz) from sequential, sun-synchronous, polar-orbiting NOAA satellites contain small systematic errors. Some of these errors are time-dependent and some are time-independent. Small errors in Ch 2 data of successive satellites arise from calibration differences. Also, successive NOAA satellites tend to have different Local Equatorial Crossing Times (LECT), which introduce differences in Ch 2 data due to the diurnal cycle. These two sources of systematic error are largely time independent. However, because of atmospheric drag, there can be a drift in the LECT of a given satellite, which introduces time-dependent systematic errors. One of these errors is due to the progressive chance in the diurnal cycle and the other is due to associated chances in instrument heating by the sun. In order to infer global temperature trend from the these MSU data, we have eliminated explicitly the time-independent systematic errors. Both of the time-dependent errors cannot be assessed from each satellite. For this reason, their cumulative effect on the global temperature trend is evaluated implicitly. Christy et al. (1998) (CSL). based on their method of analysis of the MSU Ch 2 data, infer a global temperature cooling trend (-0.046 K per decade) from 1979 to 1997, although their near nadir measurements yield near zero trend (0.003 K/decade). Utilising an independent method of analysis, we infer global temperature warmed by 0.12 +/- 0.06 C per decade from the observations of the MSU Ch 2 during the period 1980 to 1997.

Environmental effects of magmatic sulfur emitted by large-scale flood basalt eruptions

NASA Astrophysics Data System (ADS)

Schmidt, A.; Skeffington, R.; Thordarson, T.; Self, S.; Forster, P.; Rap, A.; Ridgwell, A.; Fowler, D.; Wilson, M.; Mann, G.; Wignall, P.; Carslaw, K. S.

2015-12-01

Continental flood basalt (CFB) volcanism has been temporally, and therefore causally, linked to periods of environmental crisis in the past 260 Ma. The majority of the proposed causal relationships are, however, qualitative, in particular the potential climatic and environmental effects of large amounts of sulfur dioxide (SO2) emitted to the atmosphere. CFB provinces are typically formed by numerous individual eruptions, each lasting years to decades, with highly uncertain periods of quiescence lasting hundreds to thousands of years. I will present results obtained from a global aerosol-climate model set-up to simulate the sulfur-induced climatic and environmental effects of individual decade to century-long CFB eruptions. For sulfur dioxide emissions representative of a single decade-long eruption in the 65 Ma Deccan Trap Volcanic Province, the model predicts a substantial reduction in global surface temperature of 4.5 K, which is in good agreement with multi-proxy palaeo-temperature records. However, the calculated cooling is short-lived and temperatures recover within less than 50 years once volcanic activity ceases. In contrast to previous studies, I show that acid rain from decade-long eruptions cannot cause widespread vegetation stress or loss due to the buffering capacities of soils. The direct exposure of vegetation to acid mists and fogs, however, could cause damage where the exposure is high and sustained, such as at high elevations. Finally, I will use these modeling results to place constraints on the likely environmental effects and habitability by simulating different eruption frequencies and durations as well as hiatus periods and by comparing to the proxy records.

Multi-decadal trend and space-time variability of sea level over the Indian Ocean since the 1950s: impact of decadal climate modes

NASA Astrophysics Data System (ADS)

Han, W.; Stammer, D.; Meehl, G. A.; Hu, A.; Sienz, F.

2016-12-01

Sea level varies on decadal and multi-decadal timescales over the Indian Ocean. The variations are not spatially uniform, and can deviate considerably from the global mean sea level rise (SLR) due to various geophysical processes. One of these processes is the change of ocean circulation, which can be partly attributed to natural internal modes of climate variability. Over the Indian Ocean, the most influential climate modes on decadal and multi-decadal timescales are the Interdecadal Pacific Oscillation (IPO) and decadal variability of the Indian Ocean dipole (IOD). Here, we first analyze observational datasets to investigate the impacts of IPO and IOD on spatial patterns of decadal and interdecadal (hereafter decal) sea level variability & multi-decadal trend over the Indian Ocean since the 1950s, using a new statistical approach of Bayesian Dynamical Linear regression Model (DLM). The Bayesian DLM overcomes the limitation of "time-constant (static)" regression coefficients in conventional multiple linear regression model, by allowing the coefficients to vary with time and therefore measuring "time-evolving (dynamical)" relationship between climate modes and sea level. For the multi-decadal sea level trend since the 1950s, our results show that climate modes and non-climate modes (the part that cannot be explained by climate modes) have comparable contributions in magnitudes but with different spatial patterns, with each dominating different regions of the Indian Ocean. For decadal variability, climate modes are the major contributors for sea level variations over most region of the tropical Indian Ocean. The relative importance of IPO and decadal variability of IOD, however, varies spatially. For example, while IOD decadal variability dominates IPO in the eastern equatorial basin (85E-100E, 5S-5N), IPO dominates IOD in causing sea level variations in the tropical southwest Indian Ocean (45E-65E, 12S-2S). To help decipher the possible contribution of external forcing to the multi-decadal sea level trend and decadal variability, we also analyze the model outputs from NCAR's Community Earth System Model (CESM) Large Ensemble Experiments, and compare the results with our observational analyses.

Observations of changes in the dissolved CO2 system in the North Sea, in four summers of the 2001-2011 decade

NASA Astrophysics Data System (ADS)

Clargo, Nicola; Salt, Lesley; Thomas, Helmuth; de Baar, Hein

2015-04-01

Since the industrial revolution, atmospheric concentrations of carbon dioxide (CO2) have risen dramatically, largely due to the combustion of fossil fuels, changes in land-use patterns and the production of cement. The oceans have absorbed a large amount of this CO2, with resulting impacts on ocean chemistry. Coastal seas play a significant role in the mitigation of anthropogenic atmospheric CO2 as they contribute approximately 10-30% of global primary productivity despite accounting for only 7% of the surface area. The North Sea is a perfect natural laboratory in which to study the CO2 system as it consists of two biogeochemically distinct regions displaying both oceanic and relatively coastal behaviour. It has also been identified as a continental shelf pump with respect to CO2, transporting it to the deeper waters of the North Atlantic. Large scale forcing has been shown to have a significant impact on the CO2 system over varying time scales, often masking the effects of anthropogenic influence. Here, we present data from the North Sea spanning the 2001-2011 decade. In order to investigate the dynamics of the dissolved CO2 system in this region in the face of climate change, four basin-wide cruises were conducted during the summers of 2001, 2005, 2008 and 2011. The acquired Dissolved Inorganic Carbon (DIC) and alkalinity data were then used to fully resolve the carbon system in order to assess trends over the 2001-2011 decade. We find significant interannual variability, but with a consistent, notable trend in decreasing pH. We found that surface alkalinity remained relatively constant over the decade, whereas DIC increased, indicating that the pH decline is DIC-driven. We also found that the partial pressure of CO2 (pCO2) increased faster than concurrent atmospheric CO2 concentrations, and that the CO2 buffering capacity of the North Sea decreased over the decade, with implications for future CO2 uptake.

Stevens Institute SYS-625 Final Paper: Busy Parents Need Extremely Fast, Quality Home-Cooked Dinners That Their Kids Will Eat

DOE Office of Scientific and Technical Information (OSTI.GOV)

Meyers, Carol A.

This study provides a modern take on an age-old need: busy parents need extremely fast, high quality home-cooked dinners that their kids will eat. In the past decade, the number of choices that parents have for filling this need have proliferated, largely due to technological advances. Our study proposes to leverage this technology in building a system geared toward decreasing whining in kids and increasing the sanity of their parents.

It's Time for an Ambitious National Investment in America's Children: Investments in Early Childhood Care and Education Would Have Enormous Benefits for Children, Families, Society, and the Economy

ERIC Educational Resources Information Center

Bivens, Josh; García, Emma; Gould, Elise; Weiss, Elaine; Wilson, Valerie

2016-01-01

Nearly 7 years into the recovery from the Great Recession, two glaring problems remain in the U.S. economy. One is a significant slowdown in the growth of productivity (the amount of output and income generated in an average hour of work). The other is the destructive rise in income inequality in recent decades due largely to big corporations and…

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chen, Yong, E-mail: 83229994@qq.com; Ge, Hao, E-mail: haoge@pku.edu.cn; Xiong, Jie, E-mail: jiexiong@umac.mo

Fluctuation theorem is one of the major achievements in the field of nonequilibrium statistical mechanics during the past two decades. There exist very few results for steady-state fluctuation theorem of sample entropy production rate in terms of large deviation principle for diffusion processes due to the technical difficulties. Here we give a proof for the steady-state fluctuation theorem of a diffusion process in magnetic fields, with explicit expressions of the free energy function and rate function. The proof is based on the Karhunen-Loève expansion of complex-valued Ornstein-Uhlenbeck process.

A 70-year record of outlet glacier retreat in northern Greenland

NASA Astrophysics Data System (ADS)

Hill, Emily; Carr, Rachel; Stokes, Chris; Gudmundsson, Hilmar

2017-04-01

Over the past two decades, the Greenland Ice Sheet (GrIS) has undergone accelerated mass loss increasing its contribution to sea level rise. This is partly attributed to increased mass loss from dynamic marine-terminating outlet glaciers. Despite marine-terminating outlet glaciers in northern Greenland draining 40% of the ice sheet by area, they are comparatively less well-studied than other regions of the ice sheet (e.g. central west or south-east). This region could be susceptible to marine-ice sheet instability due to large proportions of the bedrock rested below sea level and is also unique in the presence of large floating ice tongues. Here, we use a range of satellite imagery sources, accompanied by historical maps, to examine multi-decadal front position changes at 21 outlet glaciers in northern Greenland between 1948 and 2016. We accompany these terminus changes, with annual records of ice velocity, climate-ocean forcing data, and glacier-specific factors (e.g. fjord-width and basal topography) to understand the dominant forcing on glacier dynamics in the region. Over the last 70 years, there has been a clear pattern of glacier retreat in northern Greenland. This is particularly notable during the last two decades, where 62% of our study glaciers showed accelerated retreat. This was most notable at Humboldt, Tracy, Hagen Brae, C. H. Ostenfeld and Petermann Glaciers, and in the case of the latter three glaciers, this involved substantial retreat of their floating ice tongues (> 10 km). Alongside retreat, several study glaciers underwent simultaneous velocity increases. However, the collapse of floating ice tongues did not always result in increased velocity. Similar to other regions of the ice sheet, recent glacier retreat in the northern regions of the Greenland Ice Sheet could be linked to climatic-oceanic forcing, but at this stage this remains largely unknown. This response to external forcing is further complicated by the presence of glacier-surging recorded at several of our study glaciers. As northern Greenland is predicted to undergo greater warming due to Arctic amplification during the 21st century, we conclude that the region could become an increasingly important source of mass loss.

Phytoremediation removal rates of benzene, toluene, and chlorobenzene.

PubMed

Limmer, Matt A; Wilson, Jordan; Westenberg, David; Lee, Amy; Siegman, Mark; Burken, Joel G

2018-06-07

Phytoremediation is a sustainable remedial approach, although performance efficacy is rarely reported. In this study, we assessed a phytoremediation plot treating benzene, toluene, and chlorobenzene. A comparison of the calculated phytoremediation removal rate with estimates of onsite contaminant mass was used to forecast cleanup periods. The investigation demonstrated that substantial microbial degradation was occurring in the subsurface. Estimates of transpiration indicated that the trees planted were removing approximately 240,000 L of water per year. This large quantity of water removal implies substantial removal of contaminant due to large amounts of contaminants in the groundwater; however, these contaminants extensively sorb to the soil, resulting in large quantities of contaminant mass in the subsurface. The total estimate of subsurface contaminant mass was also complicated by the presence of non-aqueous phase liquids (NAPL), additional contaminant masses that were difficult to quantify. These uncertainties of initial contaminant mass at the site result in large uncertainty in the cleanup period, although mean estimates are on the order of decades. Collectively, the model indicates contaminant removal rates on the order of 10 -2 -10 0 kg/tree/year. The benefit of the phytoremediation system is relatively sustainable cleanup over the long periods necessary due to the presence of NAPL.

The inorganic carbon distribution in Irish coastal waters

NASA Astrophysics Data System (ADS)

McGrath, Triona; Cave, Rachel; McGovern, Evin; Kivimae, Caroline

2014-05-01

Despite their relatively small surface area, coastal and shelf waters play a crucial role in the global climate through their influence on major biogeochemical cycles. Due to growing concern about ocean acidification as a result of increasing atmospheric CO2 concentrations, measurements of inorganic carbon parameters (dissolved inorganic carbon (DIC), total alkalinity (TA), pH and pCO2) have been made with increasing regularity over the past two decades. While it is clear that open ocean surface waters are acidifying at a fairly uniform rate ( -0.02 pH units per decade), less is known about changes in coastal waters due to the high complexity and spatial variability in these regions. Large spatial and temporal variability in coastal CO2 parameters is mainly due to nutrient inputs, biological activity, upwelling and riverine inputs of alkalinity and inorganic and organic carbon. The inorganic carbon system in Irish coastal waters is presented here, gathered from 9 surveys around the Irish coastline between 2009 and 2013. There are striking contrasts in the CO2 system between different areas, largely attributed to the bedrock composition of the nearby rivers. Freshwater end-member concentrations of TA, calculated from TA-salinity relationships in outer estuarine and nearshore coastal water, were supported by riverine TA data from the Irish Environmental Protection Agency. A large portion of Ireland is covered with limestone bedrock and as a result, many of the rivers have extremely high TA (>5000μmol/kg) due to the carbonate mineral content of the underlying bedrock. While such high TA has resulted in elevated pH and calcium carbonate saturation states in some coastal waters, (e.g. Galway Bay and Dublin Bay), the high TA in other areas was accompanied by particularly high DIC (e.g. River Shannon on the west coast), resulting in lower pH and aragonite/calcite saturation states and even CO2 degassing in the Shannon estuary. Due to non-limestone lithology in many parts of Northern Ireland, rivers and surrounding coastal water have lower TA and hence calcium carbonate saturation states that are directly related to salinity (e.g. Lough Foyle). This study highlights the complexity of the inorganic carbon system in Irish waters and the need for region-specific case studies to be carried out to assess the potential impacts of ocean acidification on coastal ecosystems.

Tips and tricks for preparing lampbrush chromosome spreads from Xenopus tropicalis oocytes.

PubMed

Penrad-Mobayed, May; Kanhoush, Rasha; Perrin, Caroline

2010-05-01

Due to their large size and fine organization, lampbrush chromosomes (LBCs) of amphibian oocytes have been for decades one of the favorite tools of biologists for the analysis of transcriptional and post-transcriptional processes at the cytological level. The emergence of the diploid Xenopus tropicalis amphibian as a model organism for vertebrate developmental genetics and the accumulation of sequence data made available by its recent genomic sequencing, strongly revive the interest of LBCs as a powerful tool to study genes expressed during oogenesis. We describe here a detailed protocol for preparing LBCs from X. tropicalis oocyte and give practical advice to encourage a large number of researchers to become familiar with these chromosomes.

Status and Path Forward for the Large Ultraviolet Optical Infrared Surveyor (LUVOIR) Mission Concept Study

NASA Technical Reports Server (NTRS)

Crooke, Julie A.; Roberge, Aki; Domagal-Goldman, Shawn D.; Mandell, Avram M.; Bolcar, Matthew R.; Rioux, Norman M.; Perez, Mario R.; Smith, Erin C.

2016-01-01

In preparation of the 2020 Astrophysics Decadal Survey, National Aeronautics and Space Administration (NASA) has commenced a process for the astronomical community to study several large mission concepts leveraging the lessons learned from past Decadal Surveys. This will enable the Decadal Survey committee to make more informed recommendations to NASA on its astrophysics science and mission priorities with respect to cost and risk. Four astrophysics large mission concepts were identified. Each of them had a Science and Technology Definition Teem(STDT) chartered to produce scientifically compelling, feasible, and executable design reference mission (DRM)concepts to present to the 2020 Decadal Survey. In addition, The Aerospace Corporation will perform an independent cost and technical evaluation (CATE) of each of these mission concept studies in advance of the 2020 Decadal Survey by interacting with the STDTs to provide detailed technical details on certain areas for which deep dives are appropriate. This paper presents the status and path forward for one of the four large mission concepts, namely, the Large UltraViolet, Optical, InfraRed surveyor (LUVOIR).

Status and path forward for the large ultraviolet/optical/infrared surveyor (LUVOIR) mission concept study

NASA Astrophysics Data System (ADS)

Crooke, Julie A.; Roberge, Aki; Domagal-Goldman, Shawn D.; Mandell, Avi M.; Bolcar, Matthew R.; Rioux, Norman M.; Perez, Mario R.; Smith, Erin C.

2016-07-01

In preparation of the 2020 Astrophysics Decadal Survey, National Aeronautics and Space Administration (NASA) has commenced a process for the astronomical community to study several large mission concepts leveraging the lessons learned from past Decadal Surveys. This will enable the Decadal Survey committee to make more informed recommendations to NASA on its astrophysics science and mission priorities with respect to cost and risk. Four astrophysics large mission concepts were identified. Each of them had a Science and Technology Definition Teem (STDT) chartered to produce scientifically compelling, feasible, and executable design reference mission (DRM) concepts to present to the 2020 Decadal Survey. In addition, The Aerospace Corporation will perform an independent cost and technical evaluation (CATE) of each of these mission concept studies in advance of the 2020 Decadal Survey, by interacting with the STDTs to provide detailed technical details on certain areas for which "deep dives" are appropriate. This paper presents the status and path forward for one of the four large mission concepts, namely, the Large UltraViolet, Optical, InfraRed surveyor (LUVOIR).

Glycemic extremes in youth with T1DM: the structural and functional integrity of the developing brain.

PubMed

Arbelaez, Ana Maria; Semenkovich, Katherine; Hershey, Tamara

2013-12-01

The adult brain accounts for a disproportionally large percentage of the body’s total energy consumption (1). However, during brain development,energy demand is even higher, reaching the adult rate by age 2 and increasing to nearly twice the adult rate by age 10, followed by gradual reduction toward adult levels in the next decade (1,2). The dramatic changes in brain metabolism occurring over the first two decades of life coincide with the initial proliferation and then pruning of synapses to adult levels.The brain derives its energy almost exclusively from glucose and is largely driven by neuronal signaling, biosynthesis, and neuroprotection (3–6).Glucose homeostasis in the body is tightly regulated by a series of hormones and physiologic responses. As a result, hypoglycemia and hyperglycemia are rare occurrences in normal individuals, but they occur commonly inpatients with type 1 diabetes mellitus (T1DM) due to a dysfunction of peripheral glucose-insulin-glucagon responses and non-physiologic doses of exogenous insulin, which imperfectly mimic normal physiology. These extremes can occur more frequently in children and adolescents with T1DM due to the inadequacies of insulin replacement therapy, events leading to the diagnosis [prolonged untreated hyperglycemia and diabetic ketoacidosis (DKA)], and to behavioral factors interfering with optimal treatment. When faced with fluctuations in glucose supply the metabolism of the body and brain change dramatically, largely to conserve resources and, at a cost to other organs, to preserve brain function (7). However,if the normal physiological mechanisms that prevent these severe glucose fluctuations and maintain homeostasis are impaired, neuronal function and potentially viability can be affected (8–11).

Impacts of large-scale atmospheric circulation changes in winter on black carbon transport and deposition to the Arctic

NASA Astrophysics Data System (ADS)

Pozzoli, Luca; Dobricic, Srdan; Russo, Simone; Vignati, Elisabetta

2017-10-01

Winter warming and sea-ice retreat observed in the Arctic in the last decades may be related to changes of large-scale atmospheric circulation pattern, which may impact the transport of black carbon (BC) to the Arctic and its deposition on the sea ice, with possible feedbacks on the regional and global climate forcing. In this study we developed and applied a statistical algorithm, based on the maximum likelihood estimate approach, to determine how the changes of three large-scale weather patterns associated with increasing temperatures in winter and sea-ice retreat in the Arctic impact the transport of BC to the Arctic and its deposition. We found that two atmospheric patterns together determine a decreasing winter deposition trend of BC between 1980 and 2015 in the eastern Arctic while they increase BC deposition in the western Arctic. The increasing BC trend is mainly due to a pattern characterized by a high-pressure anomaly near Scandinavia favouring the transport in the lower troposphere of BC from Europe and North Atlantic directly into to the Arctic. Another pattern with a high-pressure anomaly over the Arctic and low-pressure anomaly over the North Atlantic Ocean has a smaller impact on BC deposition but determines an increasing BC atmospheric load over the entire Arctic Ocean with increasing BC concentrations in the upper troposphere. The results show that changes in atmospheric circulation due to polar atmospheric warming and reduced winter sea ice significantly impacted BC transport and deposition. The anthropogenic emission reductions applied in the last decades were, therefore, crucial to counterbalance the most likely trend of increasing BC pollution in the Arctic.

Role of the North Atlantic Oscillation in decadal temperature trends

NASA Astrophysics Data System (ADS)

Iles, Carley; Hegerl, Gabriele

2017-11-01

Global temperatures have undergone periods of enhanced warming and pauses over the last century, with greater variations at local scales due to internal variability of the climate system. Here we investigate the role of the North Atlantic Oscillation (NAO) in decadal temperature trends in the Northern Hemisphere for periods with large decadal NAO trends. Using a regression based technique we find a best estimate that trends in the NAO more than halved (reduced by 57%, 5%-95%: 47%-63%) the winter warming over the Northern Hemisphere extratropics (NH; 30N-90N) from 1920-1971 and account for 45% (±14%) of the warming there from 1963-1995, with larger impacts on regional scales. Over the period leading into the so-called warming hiatus, 1989-2013, the NAO reduced NH winter warming to around one quarter (24%; 19%-31%) of what it would have been, and caused large negative regional trends, for example, in Northern Eurasia. Warming is more spatially uniform across the Northern Hemisphere after removing the NAO influence in winter, and agreement with multi-model mean simulated trends improves. The impact of the summer NAO is much weaker, but still discernible over Europe, North America and Greenland, with the downward trend in the summer NAO from 1988-2012 reducing warming by about a third in Northern Europe and a half in North America. A composite analysis using CMIP5 control runs suggests that the ocean response to prolonged NAO trends may increase the influence of decadal NAO trends compared to estimates based on interannual regressions, particularly in the Arctic. Results imply that the long-term NAO trends over the 20th century alternately masked or enhanced anthropogenic warming, and will continue to temporarily offset or enhance its effects in the future.

Comment on "Methodology and results of calculating Central California surface temperature trends: evidence of human-induced climate change?" by Christy et al. (2006)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bonfils, C; Duffy, P; Lobell, D

2006-03-28

Understanding the causes of observed regional temperature trends is essential to projecting the human influences on climate, and the societal impacts of these influences. In their recent study, Christy et al. (2006, hereinafter CRNG06) hypothesized that the presence of irrigated soils is responsible for rapid warming of summer nights occurring in California's Central Valley over the last century (1910-2003), an assumption that rules out any significant effect due to increased greenhouse gases, urbanization, or other factors in this region. We question this interpretation, which is based on an apparent contrast in summer nighttime temperature trends between the San Joaquin Valleymore » ({approx} +0.3 {+-} 0.1 C/decade) and the adjacent western slopes of the Sierra Nevada (-0.25 {+-} 0.15 C/decade), as well as the amplitude, sign and uncertainty of the Sierra nighttime temperature trend itself. We, however, do not dispute the finding of other Sierra and Valley trends. Regarding the veracity of the apparent Sierra nighttime temperature trend, CRNG06 generated the Valley and Sierra time-series using a meticulous procedure that eliminates discontinuities and isolates homogeneous segments in temperature records from 41 weather stations. This procedure yields an apparent cooling of about -0.25 {+-} 0.15 C/decade in the Sierra region. However, because removal of one of the 137 Sierra segments, from the most elevated site (Huntington Lake, 2140m), causes an increase in nighttime temperature trend as large as the trend itself (of +0.25 C/decade, CH06), and leads to a zero trend, the apparent cooling of summer nights in the Sierra regions seems, in fact, largely uncertain.« less

Change in frozen soils and its effect on regional hydrology, upper Heihe basin, northeastern Qinghai-Tibetan Plateau

NASA Astrophysics Data System (ADS)

Gao, Bing; Yang, Dawen; Qin, Yue; Wang, Yuhan; Li, Hongyi; Zhang, Yanlin; Zhang, Tingjun

2018-02-01

Frozen ground has an important role in regional hydrological cycles and ecosystems, particularly on the Qinghai-Tibetan Plateau (QTP), which is characterized by high elevations and a dry climate. This study modified a distributed, physically based hydrological model and applied it to simulate long-term (1971-2013) changes in frozen ground its the effects on hydrology in the upper Heihe basin, northeastern QTP. The model was validated against data obtained from multiple ground-based observations. Based on model simulations, we analyzed spatio-temporal changes in frozen soils and their effects on hydrology. Our results show that the area with permafrost shrank by 8.8 % (approximately 500 km2), predominantly in areas with elevations between 3500 and 3900 m. The maximum depth of seasonally frozen ground decreased at a rate of approximately 0.032 m decade-1, and the active layer thickness over the permafrost increased by approximately 0.043 m decade-1. Runoff increased significantly during the cold season (November-March) due to an increase in liquid soil moisture caused by rising soil temperatures. Areas in which permafrost changed into seasonally frozen ground at high elevations showed especially large increases in runoff. Annual runoff increased due to increased precipitation, the base flow increased due to changes in frozen soils, and the actual evapotranspiration increased significantly due to increased precipitation and soil warming. The groundwater storage showed an increasing trend, indicating that a reduction in permafrost extent enhanced the groundwater recharge.

Estimation of p,p'-DDT degradation in soil by modeling and constraining hydrological and biogeochemical controls.

PubMed

Sanka, Ondrej; Kalina, Jiri; Lin, Yan; Deutscher, Jan; Futter, Martyn; Butterfield, Dan; Melymuk, Lisa; Brabec, Karel; Nizzetto, Luca

2018-08-01

Despite not being used for decades in most countries, DDT remains ubiquitous in soils due to its persistence and intense past usage. Because of this it is still a pollutant of high global concern. Assessing long term dissipation of DDT from this reservoir is fundamental to understand future environmental and human exposure. Despite a large research effort, key properties controlling fate in soil (in particular, the degradation half-life (τ soil )) are far from being fully quantified. This paper describes a case study in a large central European catchment where hundreds of measurements of p,p'-DDT concentrations in air, soil, river water and sediment are available for the last two decades. The goal was to deliver an integrated estimation of τ soil by constraining a state-of-the-art hydrobiogeochemical-multimedia fate model of the catchment against the full body of empirical data available for this area. The INCA-Contaminants model was used for this scope. Good predictive performance against an (external) dataset of water and sediment concentrations was achieved with partitioning properties taken from the literature and τ soil estimates obtained from forcing the model against empirical historical data of p,p'-DDT in the catchment multicompartments. This approach allowed estimation of p,p'-DDT degradation in soil after taking adequate consideration of losses due to runoff and volatilization. Estimated τ soil ranged over 3000-3800 days. Degradation was the most important loss process, accounting on a yearly basis for more than 90% of the total dissipation. The total dissipation flux from the catchment soils was one order of magnitude higher than the total current atmospheric input estimated from atmospheric concentrations, suggesting that the bulk of p,p'-DDT currently being remobilized or lost is essentially that accumulated over two decades ago. Copyright © 2018 Elsevier Ltd. All rights reserved.

Determinants of Police Strength in Large U.S. Cities during the 1990s: A Fixed-Effects Panel Analysis

ERIC Educational Resources Information Center

McCarty, William P.; Ren, Ling; Zhao, Jihong

2012-01-01

The 1990s represented a unique decade in which to analyze the determinants of police strength in the United States. This decade was a time in which crime initially increased, then substantially decreased. Furthermore, this decade also was characterized by increases in the minority population throughout large American cities. Finally, the 1990s…

Model tropical Atlantic biases underpin diminished Pacific decadal variability

NASA Astrophysics Data System (ADS)

McGregor, Shayne; Stuecker, Malte F.; Kajtar, Jules B.; England, Matthew H.; Collins, Mat

2018-06-01

Pacific trade winds have displayed unprecedented strengthening in recent decades1. This strengthening has been associated with east Pacific sea surface cooling2 and the early twenty-first-century slowdown in global surface warming2,3, amongst a host of other substantial impacts4-9. Although some climate models produce the timing of these recently observed trends10, they all fail to produce the trend magnitude2,11,12. This may in part be related to the apparent model underrepresentation of low-frequency Pacific Ocean variability and decadal wind trends2,11-13 or be due to a misrepresentation of a forced response1,14-16 or a combination of both. An increasingly prominent connection between the Pacific and Atlantic basins has been identified as a key driver of this strengthening of the Pacific trade winds12,17-20. Here we use targeted climate model experiments to show that combining the recent Atlantic warming trend with the typical climate model bias leads to a substantially underestimated response for the Pacific Ocean wind and surface temperature. The underestimation largely stems from a reduction and eastward shift of the atmospheric heating response to the tropical Atlantic warming trend. This result suggests that the recent Pacific trends and model decadal variability may be better captured by models with improved mean-state climatologies.

Study of climate change impact in Himalayan Water Resource: a case study of Nepal

NASA Astrophysics Data System (ADS)

Joshi, H. P.

2015-12-01

Himalayan region are regarded as water tower of Asia and has also covered high attention due to climate change owing to its glaciers melting. Water from those glaciers-fed basins are mostly utilized for hydropower, irrigation and drinking water supply to around 1.4 billion population downstream. The basin system, particularly in Nepal, is divided into three categories: (i) snow and glaciers fed: Koshi, Gandaki, Karnali and Mahakali basins (ii) from Mahabharat range: Babai, West Rapti, Bagmati, Kamala, Karnali, Mechi and (iii) Streams and rivulets from Chure hills: Surahinala, Badganga, Mohana etc. This study shows majority of flow (~78% of average flow) is from first category, 9% from second and 13% from third category. In the recent decades, especially during the dry season, rivers from third category have low runoff (or even zero)which leads to lack of water for irrigation and drinking water supply by lowering its water table.Interestingly, during monsoon season the whole region is facing high risks of flash floods and landslides due to unpredictable rainfall pattern. Increasing temperature trend (0.08˚Ca-1) and weakening precipitation rate (7.9±1.2 mm a-1) for last four decades shows indirect sign of climate change, though long time series in-situ observations are largely lacking in Nepal Himalaya. Our study supports high impact of climate change on potential generation of hydropower in Nepal which are more pronounced in coming decades.

Mass spectrometry for biomarker development

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wu, Chaochao; Liu, Tao; Baker, Erin Shammel

2015-06-19

Biomarkers potentially play a crucial role in early disease diagnosis, prognosis and targeted therapy. In the past decade, mass spectrometry based proteomics has become increasingly important in biomarker development due to large advances in technology and associated methods. This chapter mainly focuses on the application of broad (e.g. shotgun) proteomics in biomarker discovery and the utility of targeted proteomics in biomarker verification and validation. A range of mass spectrometry methodologies are discussed emphasizing their efficacy in the different stages in biomarker development, with a particular emphasis on blood biomarker development.

The development of non-coding RNA ontology.

PubMed

Huang, Jingshan; Eilbeck, Karen; Smith, Barry; Blake, Judith A; Dou, Dejing; Huang, Weili; Natale, Darren A; Ruttenberg, Alan; Huan, Jun; Zimmermann, Michael T; Jiang, Guoqian; Lin, Yu; Wu, Bin; Strachan, Harrison J; de Silva, Nisansa; Kasukurthi, Mohan Vamsi; Jha, Vikash Kumar; He, Yongqun; Zhang, Shaojie; Wang, Xiaowei; Liu, Zixing; Borchert, Glen M; Tan, Ming

2016-01-01

Identification of non-coding RNAs (ncRNAs) has been significantly improved over the past decade. On the other hand, semantic annotation of ncRNA data is facing critical challenges due to the lack of a comprehensive ontology to serve as common data elements and data exchange standards in the field. We developed the Non-Coding RNA Ontology (NCRO) to handle this situation. By providing a formally defined ncRNA controlled vocabulary, the NCRO aims to fill a specific and highly needed niche in semantic annotation of large amounts of ncRNA biological and clinical data.

Global temperature responses to current emissions from the transport sectors

PubMed Central

Berntsen, Terje; Fuglestvedt, Jan

2008-01-01

Transport affects climate directly and indirectly through mechanisms that cause both warming and cooling of climate, and the effects operate on very different timescales. We calculate climate responses in terms of global mean temperature and find large differences between the transport sectors with respect to the size and mix of short- and long-lived effects, and even the sign of the temperature response. For year 2000 emissions, road transport has the largest effect on global mean temperature. After 20 and 100 years the response in net temperature is 7 and 6 times higher, respectively, than for aviation. Aviation and shipping have strong but quite uncertain short-lived warming and cooling effects, respectively, that dominate during the first decades after the emissions. For shipping the net cooling during the first 4 decades is due to emissions of SO2 and NOx. On a longer timescale, the current emissions from shipping cause net warming due to the persistence of the CO2 perturbation. If emissions stay constant at 2000 levels, the warming effect from road transport will continue to increase and will be almost 4 times larger than that of aviation by the end of the century. PMID:19047640

Changes in Global Tropospheric OH Expected as a Result of Climate Change Over the Last Several Decades

NASA Technical Reports Server (NTRS)

Nicely, Julie M.; Salawitch, Ross J.; Canty, Timothy P.; Douglass, Anne R.; Duncan, Bryan N.; Lang, C.; Liang, Qing; Oman, Luke D.; Rodriguez, Jose M.; Stolarksi, Richard;

Toward a Social Psychophysics of Face Communication.

PubMed

Jack, Rachael E; Schyns, Philippe G

2017-01-03

As a highly social species, humans are equipped with a powerful tool for social communication-the face. Although seemingly simple, the human face can elicit multiple social perceptions due to the rich variations of its movements, morphology, and complexion. Consequently, identifying precisely what face information elicits different social perceptions is a complex empirical challenge that has largely remained beyond the reach of traditional methods. In the past decade, the emerging field of social psychophysics has developed new methods to address this challenge, with the potential to transfer psychophysical laws of social perception to the digital economy via avatars and social robots. At this exciting juncture, it is timely to review these new methodological developments. In this article, we introduce and review the foundational methodological developments of social psychophysics, present work done in the past decade that has advanced understanding of the face as a tool for social communication, and discuss the major challenges that lie ahead.

Recent changes of sediment flux to the western Pacific Ocean from major rivers in East and Southeast Asia

NASA Astrophysics Data System (ADS)

Wang, Houjie; Saito, Yoshiki; Zhang, Yong; Bi, Naishuang; Sun, Xiaoxiao; Yang, Zuosheng

2011-09-01

The five largest rivers in East and Southeast Asia (Yellow, Yangtze, Pearl, Red and Mekong) are important contributors of terrigenous sediment to the western Pacific Ocean. Although they have annually delivered ~ 2000 × 10 9 kg of sediment to the ocean since 1000 yr BP, they presently contribute only ~ 600 × 10 9 kg/yr, which is reverting to a level typical of the relatively undisturbed watersheds before the rise in human activities in East and Southeast Asia at 2000 yr BP. During the most recent decades flow regulation by dams and sediment entrapment by reservoirs, as well as human-influenced soil erosion in the river basins, have sharply reduced the sediment delivered from the large river basins to the ocean. We constructed a time series of data on annual water discharges and sediment fluxes from these large rivers to the western Pacific Ocean covering the period 1950-2008. These data indicate that the short-term (interannual scale) variation of sediment flux is dominated by natural climatic oscillations such as the El Niño/La Niña cycle and that anthropogenic causes involving dams and land use control the long-term (decadal scale) decrease in sediment flux to the ocean. In contrast to the relatively slow historical increase in sediment flux during the period 2000-1000 yr BP, the recent sediment flux has been decreased at an accelerating rate over centennial scales. The alterations of these large river systems by both natural and anthropogenic forcing present severe environmental challenges in the coastal ocean, including the sinking of deltas and declines in coastal wetland areas due to the decreasing sediment supply. Our work thus provides a regional perspective on the large river-derived sediment flux to the ocean over millennial and decadal scales, which will be important for understanding and managing the present and future trends of delivery of terrigenous sediment to the ocean in the context of global change.

Contribution of Changing Sources and Sinks to the Growth Rate of Atmospheric Methane Concentrations for the Last Two Decades

NASA Technical Reports Server (NTRS)

Matthews, Elaine; Walter, B.; Bogner, J.; Sarma, D.; Portmey, G.; Travis, Larry (Technical Monitor)

2001-01-01

In situ measurements of atmospheric methane concentrations begun in the early 1980s show decadal trends, as well as large interannual variations, in growth rate. Recent research indicates that while wetlands can explain several of the large growth anomalies for individual years, the decadal trend may be the combined effect of increasing sinks, due to increases in tropospheric OH, and stabilizing sources. We discuss new 20-year histories of annual, global source strengths for all major methane sources, i.e., natural wetlands, rice cultivation, ruminant animals, landfills, fossil fuels, and biomass burning. We also present estimates of the temporal pattern of the sink required to reconcile these sources and atmospheric concentrations over this time period. Analysis of the individual emission sources, together with model-derived estimates of the OH sink strength, indicates that the growth rate of atmospheric methane observed over the last 20 years can only be explained by a combination of changes in source emissions and an increasing tropospheric sink. Direct validation of the global sources and the terrestrial sink is not straightforward, in part because some sources/sinks are relatively small and diffuse (e.g., landfills and soil consumption), as well as because the atmospheric record integrates multiple and substantial sources and tropospheric sinks in regions such as the tropics. We discuss ways to develop and test criteria for rejecting and/or accepting a suite of scenarios for the methane budget.

SCD's uncooled detectors and video engines for a wide-range of applications

NASA Astrophysics Data System (ADS)

Fraenkel, A.; Mizrahi, U.; Bikov, L.; Giladi, A.; Shiloah, N.; Elkind, S.; Kogan, I.; Maayani, S.; Amsterdam, A.; Vaserman, I.; Duman, O.; Hirsh, Y.; Schapiro, F.; Tuito, A.; Ben-Ezra, M.

2011-06-01

Over the last decade SCD has established a state of the art VOx μ-Bolometer product line. Due to its overall advantages this technology is penetrating a large range of systems. In addition to a large variety of detectors, SCD has also recently introduced modular video engines with an open architecture. In this paper we will describe the versatile applications supported by the products based on 17μm pitch: Low SWaP short range systems, mid range systems based on VGA arrays and high-end systems that will utilize the XGA format. These latter systems have the potential to compete with cooled 2nd Gen scanning LWIR arrays, as will be demonstrated by TRM3 system level calculations.

Emerging immunotherapy and strategies directly targeting B cells for the treatment of diffuse large B-cell lymphoma.

PubMed

Witkowska, Magdalena; Smolewski, Piotr

2015-01-01

During the last decade, significant prolonged survival in diffusive large B-cell lymphoma (DLBCL) has been observed. The efficacy of initial treatment improved mostly due to addition of a chimeric anti-CD20 monoclonal antibody (rituximab) to standard chemotherapeutic regimens. Moreover, accurate understanding of DLBCL pathogenesis and remarkable progress in gene expression profiling have led to the development of a variety of tumor-specific regimens. Novel agents target directly the pathways involved in signal transduction, lead to apoptosis and cancer cells differentiation. In this article, we mainly focus on new treatment options, such as monoclonal antibodies, tyrosine kinase inhibitors and immunomodulatory drugs, currently investigated in aggressive B-cell lymphoma with particular attention to DLBCL type.

Evaluating Effects of H2O and overhead O3 on Global Mean Tropospheric OH Concentration

NASA Technical Reports Server (NTRS)

Nicely, Julie M.; Salawitch, R.J.; Canty, T.; Lang, Chang; Duncan, Bryan; Liang, Qing; Oman, Luke David; Stolarski, Richard S.; Waugh, Darryn

2012-01-01

The oxidizing capacity of the troposphere is controlled, to a large extent, by the abundance of hydroxyl radical (OH). The global mean concentration of OH, [OH]GLOBAL, inferred from measurements of methyl chloroform, has remained relatively constant during the past several decades, despite rising levels of CH4 that should have led to a steady decline. Here we examine other factors that may have affected [OH]GLOBAL, such as the overhead burden of stratospheric O3 and tropospheric H2O, using global OH fields from the GEOS-CHEM Chemistry-Climate Model. Our analysis suggests these factors may have contributed a positive trend to [OH]GLOBAL large enough to counter the decrease due to CH4.

Microbial communities, processes and functions in acid mine drainage ecosystems.

PubMed

Chen, Lin-xing; Huang, Li-nan; Méndez-García, Celia; Kuang, Jia-liang; Hua, Zheng-shuang; Liu, Jun; Shu, Wen-sheng

2016-04-01

Acid mine drainage (AMD) is generated from the oxidative dissolution of metal sulfides when water and oxygen are available largely due to human mining activities. This process can be accelerated by indigenous microorganisms. In the last several decades, culture-dependent researches have uncovered and validated the roles of AMD microorganisms in metal sulfides oxidation and acid generation processes, and culture-independent studies have largely revealed the diversity and metabolic potentials and activities of AMD communities, leading towards a full understanding of the microbial diversity, functions and interactions in AMD ecosystems. This review describes the diversity of microorganisms and their functions in AMD ecosystems, and discusses their biotechnological applications in biomining and AMD bioremediation according to their capabilities. Copyright © 2016 Elsevier Ltd. All rights reserved.

Impact of regional climate change on human health

NASA Astrophysics Data System (ADS)

Patz, Jonathan A.; Campbell-Lendrum, Diarmid; Holloway, Tracey; Foley, Jonathan A.

2005-11-01

The World Health Organisation estimates that the warming and precipitation trends due to anthropogenic climate change of the past 30years already claim over 150,000 lives annually. Many prevalent human diseases are linked to climate fluctuations, from cardiovascular mortality and respiratory illnesses due to heatwaves, to altered transmission of infectious diseases and malnutrition from crop failures. Uncertainty remains in attributing the expansion or resurgence of diseases to climate change, owing to lack of long-term, high-quality data sets as well as the large influence of socio-economic factors and changes in immunity and drug resistance. Here we review the growing evidence that climate-health relationships pose increasing health risks under future projections of climate change and that the warming trend over recent decades has already contributed to increased morbidity and mortality in many regions of the world. Potentially vulnerable regions include the temperate latitudes, which are projected to warm disproportionately, the regions around the Pacific and Indian oceans that are currently subjected to large rainfall variability due to the El Niño/Southern Oscillation sub-Saharan Africa and sprawling cities where the urban heat island effect could intensify extreme climatic events.

Impact of regional climate change on human health.

PubMed

Patz, Jonathan A; Campbell-Lendrum, Diarmid; Holloway, Tracey; Foley, Jonathan A

2005-11-17

The World Health Organisation estimates that the warming and precipitation trends due to anthropogenic climate change of the past 30 years already claim over 150,000 lives annually. Many prevalent human diseases are linked to climate fluctuations, from cardiovascular mortality and respiratory illnesses due to heatwaves, to altered transmission of infectious diseases and malnutrition from crop failures. Uncertainty remains in attributing the expansion or resurgence of diseases to climate change, owing to lack of long-term, high-quality data sets as well as the large influence of socio-economic factors and changes in immunity and drug resistance. Here we review the growing evidence that climate-health relationships pose increasing health risks under future projections of climate change and that the warming trend over recent decades has already contributed to increased morbidity and mortality in many regions of the world. Potentially vulnerable regions include the temperate latitudes, which are projected to warm disproportionately, the regions around the Pacific and Indian oceans that are currently subjected to large rainfall variability due to the El Niño/Southern Oscillation sub-Saharan Africa and sprawling cities where the urban heat island effect could intensify extreme climatic events.

Trends in educational inequalities in cause specific mortality in Norway from 1960 to 2010: a turning point for educational inequalities in cause specific mortality of Norwegian men after the millennium?

PubMed

Strand, Bjørn Heine; Steingrímsdóttir, Ólöf Anna; Grøholt, Else-Karin; Ariansen, Inger; Graff-Iversen, Sidsel; Næss, Øyvind

2014-11-24

Educational inequalities in total mortality in Norway have widened during 1960-2000. We wanted to investigate if inequalities have continued to increase in the post millennium decade, and which causes of deaths were the main drivers. All deaths (total and cause specific) in the adult Norwegian population aged 45-74 years over five decades, until 2010 were included; in all 708,449 deaths and over 62 million person years. Two indices of inequalities were used to measure inequality and changes in inequalities over time, on the relative scale (Relative Index of Inequality, RII) and on the absolute scale (Slope Index of Inequality, SII). Relative inequalities in total mortality increased over the five decades in both genders. Among men absolute inequalities stabilized during 2000-2010, after steady, significant increases each decade back to the 1960s, while in women, absolute inequalities continued to increase significantly during the last decade. The stabilization in absolute inequalities among men in the last decade was mostly due to a fall in inequalities in cardiovascular disease (CVD) mortality and lung cancer and respiratory disease mortality. Still, in this last decade, the absolute inequalities in cause-specific mortality among men were mostly due to cardiovascular diseases (CVD) (34% of total mortality inequality), lung cancer and respiratory diseases (21%). Among women the absolute inequalities in mortality were mostly due to lung cancer and chronic lower respiratory tract diseases (30%) and CVD (27%). In men, absolute inequalities in mortality have stopped increasing, seemingly due to reduction in inequalities in CVD mortality. Absolute inequality in mortality continues to widen among women, mostly due to death from lung cancer and chronic lung disease. Relative educational inequalities in mortality are still on the rise for Norwegian men and women.

Seismic rate changes associated with seasonal, annual, and decadal changes in the cryosphere

NASA Astrophysics Data System (ADS)

Sauber, J. M.; Luthcke, S. B.; Hall, D. K.

2012-12-01

Near the Bering Glacier Global Fiducial Program (GFP) in southern Alaska large cryospheric fluctuations occur in a region of upper crustal faulting and folding associated with collision and accretion of the Yakutat terrane. In this study we report constraints on seasonal, annual and decadal cryospheric changes estimated over the last decade from field, aircraft and satellite measurements and we evaluate the influence of cryospheric changes on the background seismic rate. Multi-year images from the Bering Glacier GFP are available since mid-2003 to constrain changes in extent of the Bering Glacier and to discern feature changes in the glacial surface. Starting around the same time, satellite gravimetric measurements from the Gravity Recovery and Climate experiment (GRACE) commenced. Large spatial-scale mass change calculated from the GRACE mascon solution of Luthcke et al. [2012] indicate a general trend of annual ice mass loss for southern Alaska but with large, variable seasonal mass fluctuations. Since 2007 the station position of a continuous GPS site near Cape Yakataga (Alaska EarthScope PBO site, AB35) has been available as well. In addition to changes in the geodetic position due to tectonic motion, this GPS station shows large seasonal excursions in the detrended vertical and horizontal position components consistent with snow loading in the fall and winter and melt onset/mass decrease in the spring/summer. To better understand the timing of processes responsible for the onset of cryospheric mass loss documented in the GRACE data, we examined changes in the snow cover extent and the onset of melt in the spring. We calculated the elastic displacements of the solid Earth and theoretical earthquake failure criteria associated with these annual and seasonal ice and snow changes. Additionally, we compared the seismic rate (M>1.8) from a reference background time period against other time periods with variable ice or tectonic change characteristics to test the significance of seismic rate changes. Our earlier results suggest statistically significant changes in the background seismic rate associated with large seasonal mass changes.

Seismic Rate Changes Associated with Seasonal, Annual, and Decadal Changes in the Cryosphere

NASA Technical Reports Server (NTRS)

Sauber-Rosenberg, Jeanne

2012-01-01

Near the Bering Glacier Global Fiducial site in southern Alaska large cryospheric fluctuations occur in a region of upper crustal faulting and folding associated with collision and accretion of the Yakutat terrane. In this study we report constraints on seasonal, annual and decadal cryospheric changes estimated over the last decade from field, aircraft and satellite measurements, and we evaluate the influence of cryospheric changes on the background seismic rate. Multi-year images from the Bering Glacier global fiducial site are available since mid-2003 to constrain changes in extent of the Bering Glacier and to discern feature changes in the glacial surface. Starting around the same time, satellite gravimetric measurements from the Gravity Recovery and Climate experiment (GRACE) commenced. Large spatial-scale mass change calculated from the GRACE 1deg x 1deg mascon solution of Luthcke et al. [2012] indicate a general trend of annual ice mass loss for southern Alaska but with large, variable seasonal mass fluctuations. Since 2007, the station position of a continuous GPS site near Cape Yakataga (Alaska EarthScope PBO site, AB35) has been available as well. In addition to changes in the geodetic position due to tectonic motion, this GPS station shows large seasonal excursions in the detrended vertical and horizontal position components consistent with snow loading in the fall and winter and melt onset/mass decrease in the spring/summer. To better understand the timing of processes responsible for the onset of cryospheric mass loss documented in the GRACE data, we examined changes in the snow cover extent and the onset of melt in the spring. We calculated the surface displacements of the solid Earth and theoretical earthquake failure criteria associated with these annual and seasonal ice and snow changes using layered elastic half-space. Additionally, we compared the seismic rate (M>1.8) from a reference background time period against other time periods with variable ice or tectonic change characteristics to test the significance of seismic rate changes. Our earlier results suggest statistically significant changes in the background seismic rate associated with large seasonal mass changes. INDEX

Possible seasonality in large deep-focus earthquakes

NASA Astrophysics Data System (ADS)

Zhan, Zhongwen; Shearer, Peter M.

2015-09-01

Large deep-focus earthquakes (magnitude > 7.0, depth > 500 km) have exhibited strong seasonality in their occurrence times since the beginning of global earthquake catalogs. Of 60 such events from 1900 to the present, 42 have occurred in the middle half of each year. The seasonality appears strongest in the northwest Pacific subduction zones and weakest in the Tonga region. Taken at face value, the surplus of northern hemisphere summer events is statistically significant, but due to the ex post facto hypothesis testing, the absence of seasonality in smaller deep earthquakes, and the lack of a known physical triggering mechanism, we cannot rule out that the observed seasonality is just random chance. However, we can make a testable prediction of seasonality in future large deep-focus earthquakes, which, given likely earthquake occurrence rates, should be verified or falsified within a few decades. If confirmed, deep earthquake seasonality would challenge our current understanding of deep earthquakes.

Genetic Influences on the Development of Alcoholism

PubMed Central

Enoch, Mary-Anne

2014-01-01

Alcoholism has a substantial heritability yet the detection of specific genetic influences has largely proved elusive. The strongest findings are with genes encoding alcohol metabolizing enzymes. A few candidate genes such as GABRA2 have shown robust associations with alcoholism. Moreover, it has become apparent that variants in stress-related genes such as CRHR1, may only confer risk in individuals exposed to trauma, particularly in early life. Over the past decade there have been tremendous advances in large scale SNP genotyping technologies allowing for genome-wide associations studies (GWAS). As a result, it is now recognized that genetic risk for alcoholism is likely to be due to common variants in very many genes, each of small effect, although rare variants with large effects might also play a role. This has resulted in a paradigm shift away from gene centric studies towards analyses of gene interactions and gene networks within biologically relevant pathways. PMID:24091936

Genetic influences on the development of alcoholism.

PubMed

Enoch, Mary-Anne

2013-11-01

Alcoholism has a substantial heritability yet the detection of specific genetic influences has largely proved elusive. The strongest findings are with genes encoding alcohol metabolizing enzymes. A few candidate genes such as GABRA2 have shown robust associations with alcoholism. Moreover, it has become apparent that variants in stress-related genes such as CRHR1, may only confer risk in individuals exposed to trauma, particularly in early life. Over the past decade there have been tremendous advances in large scale SNP genotyping technologies allowing for genome-wide associations studies (GWAS). As a result, it is now recognized that genetic risk for alcoholism is likely to be due to common variants in very many genes, each of small effect, although rare variants with large effects might also play a role. This has resulted in a paradigm shift away from gene centric studies toward analyses of gene interactions and gene networks within biologically relevant pathways.

Role of internal variability in recent decadal to multidecadal tropical Pacific climate changes

NASA Astrophysics Data System (ADS)

Bordbar, Mohammad Hadi; Martin, Thomas; Latif, Mojib; Park, Wonsun

2017-05-01

While the Earth's surface has considerably warmed over the past two decades, the tropical Pacific has featured a cooling of sea surface temperatures in its eastern and central parts, which went along with an unprecedented strengthening of the equatorial trade winds, the surface component of the Pacific Walker Circulation (PWC). Previous studies show that this decadal trend in the trade winds is generally beyond the range of decadal trends simulated by climate models when forced by historical radiative forcing. There is still a debate on the origin of and the potential role that internal variability may have played in the recent decadal surface wind trend. Using a number of long control (unforced) integrations of global climate models and several observational data sets, we address the question as to whether the recent decadal to multidecadal trends are robustly classified as an unusual event or the persistent response to external forcing. The observed trends in the tropical Pacific surface climate are still within the range of the long-term internal variability spanned by the models but represent an extreme realization of this variability. Thus, the recent observed decadal trends in the tropical Pacific, though highly unusual, could be of natural origin. We note that the long-term trends in the selected PWC indices exhibit a large observational uncertainty, even hindering definitive statements about the sign of the trends.