Sample records for decagonal phases michael

  1. Atomic structure of a decagonal Al-Pd-Mn phase

    NASA Astrophysics Data System (ADS)

    Mihalkovič, Marek; Roth, Johannes; Trebin, Hans-Rainer

    2017-12-01

    We present a detailed structure solution for the 16 -Å decagonal quasicrystal in the Al-Pd-Mn system by means of cluster decoration and ab initio energy minimization. It is based on structure models of the ɛ and other approximant phases. The ɛ phases can be represented as subsets of a hexagon-boat-star (HBS) tiling. The decagonal phase comprises further HBS tiles. We have constructed several fictitious HBS approximants and optimized their structures individually. All tiles are decorated by two types of atomic clusters: the pseudo-Mackay icosahedron (PMI) and the large bicapped pentagonal prism (LBPP). It turns out that, whereas the PMI clusters can be kept essentially unchanged, the LBPP clusters must be adjusted in occupancy with Al atoms depending on their positions in the various tiles. In this way we obtain cluster decorations for all tiles of the decagonal quasicrystal. The calculations were confirmed by evaluation of an effective tile Hamiltonian.

  2. Growth of a decagonal Al 70Ni 15Co 15 single quasicrystal by the Czochralski method

    NASA Astrophysics Data System (ADS)

    Jeong, H. T.; Kim, S. H.; Kim, W. T.; Kim, D. H.; Inkson, B. J.

    2000-07-01

    Single decagonal quasicrystals of Al 70Ni 15Co 15 were grown by the Czochralski method at Ar atmosphere. The grown crystals were of single decagonal phase without any secondary phases due to the peritectic reaction and contained a large single quasicrystal of cm order size. The high quality and single quasicrystallinity of them were examined by the Laue transmission photography, single crystal X-ray diffraction, and high-resolution electron microscopy investigations.

  3. Synthesis of porous Cu from Al-Cu-Co decagonal quasicrystalline alloys

    NASA Astrophysics Data System (ADS)

    Kalai Vani, V.; Kwon, O. J.; Hong, S. M.; Fleury, E.

    2011-07-01

    The formation of a porous Cu structure from cast Al-Cu-Co decagonal quasicrystalline alloys has been studied using a selective corrosion technique. Two alkaline solutions were selected based on the electrochemical properties of the constituent elements. Selective corrosion of Al and Co was achieved by chemical immersion of the cast Al-Cu-Co alloy in both 5 M NaOH and 0.5 M Na2CO3 solutions; values for BET surface-to-weight ratio of up to 30 m2/g could be reached. Microstructural analyses indicated that the architecture of the resulting porous structures was composed of a needle-type phase, remaining from the decagonal phase, in addition to Cu and Cu-Co phases.

  4. Preparation, Characterization and Properties of Rapidly Solidified Alloys

    DTIC Science & Technology

    1986-10-01

    Biancaniello Met. Trans. A (Accepted) 3. Microsegregation in Rapidly Solidified Ag-15 wt % Cu Alloys W.J. Boettinger, L.A. Bendersky, S.R. Coriell...the alloy , leaving the tntercrystalline liquid depleted in manganese. The 15 and 18 wt % Mn ribbons both show Al (Ill) peaks which are split...same composition. The thicker ribbons of 35 and 37 wt % Mn alloys were single-phase decagonal. The decagonal phase is recognizable by its highly faulted

  5. Probing the growth and melting pathways of a decagonal quasicrystal in real-time

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Han, Insung; Xiao, Xianghui; Shahani, Ashwin J.

    How does a quasicrystal grow? Despite the decades of research that have been dedicated to this area of study, it remains one of the fundamental puzzles in the field of crystal growth. Although there has been no lack of theoretical studies on quasicrystal growth, there have been very few experimental investigations with which to test their various hypotheses. In particular, evidence of the in situ and three-dimensional (3D) growth of a quasicrystal from a parent liquid phase is lacking. To fill-in-the-gaps in our understanding of the solidification and melting pathways of quasicrystals, we performed synchrotron-based X-ray imaging experiments on amore » decagonal phase with composition of Al-15at%Ni-15at%Co. High-flux X-ray tomography enabled us to observe both growth and melting morphologies of the 3D quasicrystal at temperature. We determined that there is no time-reversal symmetry upon growth and melting of the decagonal quasicrystal. While quasicrystal growth is predominantly dominated by the attachment kinetics of atomic clusters in the liquid phase, melting is instead barrier-less and limited by buoyancy-driven convection. These experimental results provide the much-needed benchmark data that can be used to validate simulations of phase transformations involving this unique phase of matter.« less

  6. Probing the growth and melting pathways of a decagonal quasicrystal in real-time

    DOE PAGES

    Han, Insung; Xiao, Xianghui; Shahani, Ashwin J.

    2017-12-12

    How does a quasicrystal grow? Despite the decades of research that have been dedicated to this area of study, it remains one of the fundamental puzzles in the field of crystal growth. Although there has been no lack of theoretical studies on quasicrystal growth, there have been very few experimental investigations with which to test their various hypotheses. In particular, evidence of the in situ and three-dimensional (3D) growth of a quasicrystal from a parent liquid phase is lacking. To fill-in-the-gaps in our understanding of the solidification and melting pathways of quasicrystals, we performed synchrotron-based X-ray imaging experiments on amore » decagonal phase with composition of Al-15at%Ni-15at%Co. High-flux X-ray tomography enabled us to observe both growth and melting morphologies of the 3D quasicrystal at temperature. We determined that there is no time-reversal symmetry upon growth and melting of the decagonal quasicrystal. While quasicrystal growth is predominantly dominated by the attachment kinetics of atomic clusters in the liquid phase, melting is instead barrier-less and limited by buoyancy-driven convection. These experimental results provide the much-needed benchmark data that can be used to validate simulations of phase transformations involving this unique phase of matter.« less

  7. Alumina nanowire growth by water decomposition and the peritectic reaction of decagonal Al{sub 65}Cu{sub 15}Co{sub 20} quasicrystals

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Téllez-Vázquez, J.O., E-mail: oswald.tellez@gmail.com; Patiño-Carachure, C., E-mail: cpatino@pampano.unacar.mx; Rosas, G., E-mail: grtrejo@yahoo07.com.mx

    2016-02-15

    In this paper, the results of the Al{sub 2}O{sub 3} nanowires' growth through a chemical reaction between Al and water vapor at 1050 °C are presented. Our approach is based on two primary considerations. First, at room temperature, the Al{sub 65}Cu{sub 15}Co{sub 20} alloy is affected by the following mechanism: 2Al (s) + 3H{sub 2}O (g) → Al{sub 2}O{sub 3} (s) + H{sub 2} (g). In this reaction, the released hydrogen induces cleavage fracture of the material to form small particles. Second, the Al{sub 65}Cu{sub 15}Co{sub 20} quasicrystalline phase is transformed on heating to liquid + Al (Cu, Co) cubicmore » phase through a peritectic reaction at 1050 °C. The Al-rich liquid then reacts with water vapor, forming Al{sub 2}O{sub 3} nanowires. X-ray diffraction (XRD) analysis shows that the formed nanowires have a hexagonal structure, and infrared analysis further confirms the presence of α-Al{sub 2}O{sub 3} phase in the final products. Transmission electron microscopy observations show that nanoparticles are present at the end of nanowires, suggesting the VLS growth mechanism. Elemental analysis by energy dispersive spectroscopy (EDS) indicates that the particles at the tip of the nanowires are mainly formed by Co and Cu alloying elements and small amounts of Al. Electron microscopy observations showed nanowires with diameters ranging from 20 to 70 nm; the average diameter was 37 nm and the nanowire lengths were up to several micrometers. - Highlights: • Hexagonal alumina nanowires are grown at 1050 °C through the VLS process. • Alumina nanowires are obtained by the decomposition of decagonal quasicrystalline phase. • The decagonal phase decomposition follows a peritectic reaction at 1030 °C. • Nanoparticles are obtained by hydrogen embrittlement mechanism. • The nanoparticles catalyze the water decomposition to form wires.« less

  8. Structural disorder in the decagonal Al-Co-Ni. I. Patterson analysis of diffuse x-ray scattering data

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kobas, Miroslav; Weber, Thomas; Steurer, Walter

    The three-dimensional (3D) difference Patterson (autocorrelation) function of a disordered quasicrystal (Edagawa phase) has been analyzed. 3D diffuse x-ray diffraction data were collected in situ at 300, 1070, and 1120 K. A method, the punch-and-fill technique, has been developed for separating diffuse scattering and Bragg reflections. Its potential and limits are discussed in detail. The different Patterson maps are interpreted in terms of intercluster correlations as a function of temperature. Both at high and low temperatures, the clusters decorate the vertices of the same quasiperiodic covering. At low temperatures, for the disordered part of the structure, short-range intercluster correlations aremore » present, whereas at higher temperatures, medium-range intercluster correlations are formed. This indicates disorder mainly inside clusters at low temperatures, whereas at higher temperatures disorder takes place inside larger superclusters. Qualitatively, the Patterson maps may be interpreted by intercluster correlations mainly inside pentagonal superclusters below 1120 K, and inside the larger decagonal superclusters at 1120 K. The results of our diffraction study are published in two parts. Part I focuses on the 3D Patterson analysis based on experimental data, Part II reports modeling of structural disorder in decagonal Al-Co-Ni.« less

  9. Wireless sensor network for irrigation application in cotton

    USDA-ARS?s Scientific Manuscript database

    A wireless sensor network was deployed in a cotton field to monitor soil water status for irrigation. The network included two systems, a Decagon system and a microcontroller-based system. The Decagon system consists of soil volumetric water-content sensors, wireless data loggers, and a central data...

  10. Soil moisture and plant canopy temperature sensing for irrigation application in cotton

    USDA-ARS?s Scientific Manuscript database

    A wireless sensor network was deployed in a cotton field to monitor soil water status for irrigation. The network included two systems, a Decagon system and a microcontroller-based system. The Decagon system consists of soil volumetric water-content sensors, wireless data loggers, and a central data...

  11. Updating the phase diagram of the archetypal frustrated magnet Gd3Ga5O12

    NASA Astrophysics Data System (ADS)

    Deen, P. P.; Florea, O.; Lhotel, E.; Jacobsen, H.

    2015-01-01

    The applied magnetic field and temperature phase diagram of the archetypal frustrated magnet, Gd3Ga5O12 , has been reinvestigated using single-crystal magnetometry and polarized neutron diffraction. The updated phase diagram is substantially more complicated than previously reported and can be understood in terms of competing interactions with loops of spins, trimers, and decagons, in addition to competition and interplay between antiferromagnetic, incommensurate, and ferromagnetic order. Several additional distinct phase boundaries are presented. The phase diagram centers around a multiphase convergence to a single point at 0.9 T and ˜0.35 K, below which, in temperature, a very narrow magnetically disordered region exists. These data illustrate the richness and diversity that arise from frustrated exchange on the three-dimensional hyperkagome lattice.

  12. Icosahedral and decagonal quasicrystals of intermetallic compounds are multiple twins of cubic or orthorhombic crystals composed of very large atomic complexes with icosahedral point-group symmetry in cubic close packing or body-centered packing: Structure of decagonal Al6Pd

    PubMed Central

    Pauling, Linus

    1989-01-01

    A doubly icosahedral complex involves roughly spherical clusters of atoms with icosahedral point-group symmetry, which are themselves, in parallel orientation, icosahedrally packed. These complexes may form cubic crystallites; three structures of this sort have been identified. Analysis of electron diffraction photographs of the decagonal quasicrystal Al6Pd has led to its description as involving pentagonal twinning of an orthorhombic crystal with a = 51.6 Å, b = 37.6 Å, and c = 33.24 Å, with about 4202 atoms in the unit, comprising two 1980-atom doubly icosahedral complexes, each involving icosahedral packing of 45 44-atom icosahedral complexes (at 0 0 0 and 1/2 1/2 1/2) and 242 interstitial atoms. The complexes and clusters are oriented with one of their fivefold axes in the c-axis direction. Images PMID:16594092

  13. Icosahedral and decagonal quasicrystals of intermetallic compounds are multiple twins of cubic or orthorhombic crystals composed of very large atomic complexes with icosahedral point-group symmetry in cubic close packing or body-centered packing: Structure of decagonal Al(6)Pd.

    PubMed

    Pauling, L

    1989-12-01

    A doubly icosahedral complex involves roughly spherical clusters of atoms with icosahedral point-group symmetry, which are themselves, in parallel orientation, icosahedrally packed. These complexes may form cubic crystallites; three structures of this sort have been identified. Analysis of electron diffraction photographs of the decagonal quasicrystal Al(6)Pd has led to its description as involving pentagonal twinning of an orthorhombic crystal with a = 51.6 A, b = 37.6 A, and c = 33.24 A, with about 4202 atoms in the unit, comprising two 1980-atom doubly icosahedral complexes, each involving icosahedral packing of 45 44-atom icosahedral complexes (at 0 0 0 and 1/2 1/2 1/2) and 242 interstitial atoms. The complexes and clusters are oriented with one of their fivefold axes in the c-axis direction.

  14. A model for a transition from a quasicrystalline to a microcrystalline state

    NASA Astrophysics Data System (ADS)

    Coddens, G.; Launois, P.

    1991-07-01

    We propose a monoatomic model for a quasicrystal transition as observed recently in systems with icosahedral [3] and decagonal [5] symmetry. It is developed here for the case of decagonal symmetry and is inspired by the experimental results on the system Al-Cu-Co-Si [5,6]. The model goes beyond the purely geometrical description by an important physical aspect: the transition mediates through a single atomic jump distance such that only one unique double-well potential has to be invoked to describe it; in conformity with the symmetry there are 10 jump vectors. In the framework of the model, the microcrystalline state is energetically more favourable than a monocrystalline approximant phase. Nous proposons un modèle mono-atomique pour une transition quasicristal-microcristal du type de celles observées récemment dans des systèmes à symétrie icosaédrique [3] et décagonale [5]. Il est développé ici pour la symétrie décagonale et est inspiré par des résultats expérimentaux concernant l'alliage Al-Cu-Co-Si [5,6]. Le modèle va au-delà d'une description purement géometrique par un aspect physique important : la transition se fait via une seule distance de saut inter-atomique de telle sorte q'un seul double-puits de potentiel doit être pris en compte ; conformément à la symétrie, il y a 10 directions de saut. Dans le cadre du modèle, la phase microcristalline est énergétiquement favorisée par rapport à une phase approximante monocristalline.

  15. Natural quasicrystal with decagonal symmetry

    NASA Astrophysics Data System (ADS)

    Bindi, Luca; Yao, Nan; Lin, Chaney; Hollister, Lincoln S.; Andronicos, Christopher L.; Distler, Vadim V.; Eddy, Michael P.; Kostin, Alexander; Kryachko, Valery; MacPherson, Glenn J.; Steinhardt, William M.; Yudovskaya, Marina; Steinhardt, Paul J.

    2015-03-01

    We report the first occurrence of a natural quasicrystal with decagonal symmetry. The quasicrystal, with composition Al71Ni24Fe5, was discovered in the Khatyrka meteorite, a recently described CV3 carbonaceous chondrite. Icosahedrite, Al63Cu24Fe13, the first natural quasicrystal to be identified, was found in the same meteorite. The new quasicrystal was found associated with steinhardtite (Al38Ni32Fe30), Fe-poor steinhardtite (Al50Ni40Fe10), Al-bearing trevorite (NiFe2O4) and Al-bearing taenite (FeNi). Laboratory studies of decagonal Al71Ni24Fe5 have shown that it is stable over a narrow range of temperatures, 1120 K to 1200 K at standard pressure, providing support for our earlier conclusion that the Khatyrka meteorite reached heterogeneous high temperatures [1100 < T(K) <= 1500] and then rapidly cooled after being heated during an impact-induced shock that occurred in outer space 4.5 Gya. The occurrences of metallic Al alloyed with Cu, Ni, and Fe raises new questions regarding conditions that can be achieved in the early solar nebula.

  16. Structural disorder in the decagonal Al-Co-Ni. II. Modeling

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kobas, Miroslav; Weber, Thomas; Steurer, Walter

    2005-06-01

    The hydrodynamic theory of phasonic and phononic disorder is applied successfully to describe the short-range disordered structure of a decagonal Al{sub 71.5}Co{sub 14.6}Ni{sub 13.9} quasicrystal (Edagawa phase, superstructure type I). Moreover, model calculations demonstrate that the main features of diffuse scattering can be equally well described by phasonic disorder and fivefold orientational disorder of clusters. The calculations allow us to distinguish the different cluster types published so far and the best agreement with experimental data could be achieved with the mirror-symmetric Abe cluster. Modeling of phason diffuse scattering associated with the S1 and S2 superstructure reflections indicate disorder of superclusters.more » The former show basically intercluster correlations inside quasiperiodic layers, while the latter exhibit intra- and inter-cluster correlations, both between adjacent and inside quasiperiodic layers. The feasibility, potential, and limits of the Patterson method in combination with the punch-and-fill method employed is shown on the example of a phasonic disordered rhombic Penrose tiling. A variation of the elastic constants does not change qualitatively the way phasonic disorder is realized in the local quasicrystalline structure. For the same model system it is also shown that phasonic fluctuations of the atomic surfaces yield average clusters in the cut space, which correspond to fivefold orientationally disordered clusters.« less

  17. Decagonal quasicrystal and related crystalline phases in Mn-Ga alloys with 52 to 63 a/o Ga

    NASA Astrophysics Data System (ADS)

    Wu, J. S.; Kuo, K. H.

    1997-03-01

    A decagonal quasicrystal (DQC) and six related intermetallic phases with large unit cells have been found in binary Mn-Ga alloys with 52 to 63 at. pct Ga by means of transmission electron microscopy (TEM). As does the Al-Mn DQC, the Ga-Mn DQC also has a periodicity of 1.25 nm along its tenfold axis. However, its Mn content, determined by electron microprobe X-ray analysis (about 45 to 50 at. pct Mn), is much higher than that of the Al-Mn DQC (about 20 to 30 at. pct Mn). The compositions of the intermetallic phases are about 53, 56, 58, and 62 at. pct Ga, corresponding respectively to the unknown structures of MnGa (50.7 to 53.4 at. pct Ga), Mn5Ga6 (55 at pct Ga), Mn5Ga7 (57.9 at. pct Ga), and Mn3Ga5 (62.9 at. pct Ga) given in the binary Mn-Ga phase diagram ( Metals Hand-book, T.B. Massalski, J.L. Murray, L.H. Benneft, and H. Baker, eds., ASM, Metals Park, OH, 1986, vol. 2, p. 1144). Their lattice types have been determined by selected area electron diffraction. The ferromagnetic Mn3Ga5 is tetragonal, a=1.25 nm and c=2.50 nm; Mn5Ga7 is orthorhombic, a=4.57 nm, b=1.25 nm, and c=1.44 nm; Mn5Ga6 has two different but closely related orthorhombic unit cells, a=1.26 nm, b=1.25 nm, and c=1.48 nm as well as a=0.77 nm, b=1.25 nm, and c=2.36 nm; MnGa also has two different and related unit cells, one orthorhombic with a=2.04 nm, b=1.25 nm, and c=1.48 nm and the other monoclinic with a=2.59 nm, b=1.25 nm, c=1.15 nm, and β≈=110 deg. All these orthorhombic phases have b=1.25 nm, being the same as the periodicity along the tenfold axis of the Ga-Mn and Al-Mn DQCs. Moreover, all these six intermetallic phases give electron diffraction patterns displaying a pseudo-tenfold distribution of strong diffraction spots and are considered to be crystalline approximants of the Ga-Mn DQC.

  18. Atomic structure solution of the complex quasicrystal approximant Al77Rh15Ru8 from electron diffraction data.

    PubMed

    Samuha, Shmuel; Mugnaioli, Enrico; Grushko, Benjamin; Kolb, Ute; Meshi, Louisa

    2014-12-01

    The crystal structure of the novel Al77Rh15Ru8 phase (which is an approximant of decagonal quasicrystals) was determined using modern direct methods (MDM) applied to automated electron diffraction tomography (ADT) data. The Al77Rh15Ru8 E-phase is orthorhombic [Pbma, a = 23.40 (5), b = 16.20 (4) and c = 20.00 (5) Å] and has one of the most complicated intermetallic structures solved solely by electron diffraction methods. Its structural model consists of 78 unique atomic positions in the unit cell (19 Rh/Ru and 59 Al). Precession electron diffraction (PED) patterns and high-resolution electron microscopy (HRTEM) images were used for the validation of the proposed atomic model. The structure of the E-phase is described using hierarchical packing of polyhedra and a single type of tiling in the form of a parallelogram. Based on this description, the structure of the E-phase is compared with that of the ε6-phase formed in Al-Rh-Ru at close compositions.

  19. Michael Fisher at King's College London

    NASA Astrophysics Data System (ADS)

    Domb, Cyril

    1991-09-01

    Michael Fisher spent the first 16 years of his academic life in the Physics Department of King's College, London, starting as an undergraduate and ending as a full professor. A survey is undertaken of his activities and achievements during the various periods of this phase of his career.

  20. Michael Fisher at King's College London

    NASA Astrophysics Data System (ADS)

    Domb, Cyril

    Michael Fisher spent the first 16 years of his academic life in the Physics Department of King's College, London, starting as an undergraduate and ending as a full professor. A survey is undertaken of his activities and achievements during the various periods of this phase of his career.

  1. Advancement and Application of Multi-Phase CFD Modeling to High Speed Supercavitating Flows

    DTIC Science & Technology

    2013-08-13

    5a. CONTRACT NUMBER 5b. GRANT NUMBER N00014-09-1-0042 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Jules W. Lindau and Michael P. Kinzel 5d. PROJECT...REPORT U b. ABSTRACT U c. THIS PAGE U 17. LIMITATION OF ABSTRACT U 18. NUMBER OF PAGES 29 19a. NAME OF RESPONSIBLE PERSON Jules W. Lindau...Application of Multi-Phase CFD Modeling to High Speed Supercavitating Flows Michael P. Kinzel Jules W. Lindau Penn State University Applied Research

  2. Optimization of the β-Elimination/Michael Addition Chemistry on Reversed-Phase Supports for Mass Spectrometry Analysis of O-Linked Protein Modifications

    PubMed Central

    Nika, Heinz; Nieves, Edward; Hawke, David H.; Angeletti, Ruth Hogue

    2013-01-01

    We previously adapted the β-elimination/Michael addition chemistry to solid-phase derivatization on reversed-phase supports, and demonstrated the utility of this reaction format to prepare phosphoseryl peptides in unfractionated protein digests for mass spectrometric identification and facile phosphorylation-site determination. Here, we have expanded the use of this technique to β-N-acetylglucosamine peptides, modified at serine/threonine, phosphothreonyl peptides, and phosphoseryl/phosphothreonyl peptides, followed in sequence by proline. The consecutive β-elimination with Michael addition was adapted to optimize the solid-phase reaction conditions for throughput and completeness of derivatization. The analyte remained intact during derivatization and was recovered efficiently from the silica-based, reversed-phase support with minimal sample loss. The general use of the solid-phase approach for enzymatic dephosphorylation was demonstrated with phosphoseryl and phosphothreonyl peptides and was used as an orthogonal method to confirm the identity of phosphopeptides in proteolytic mixtures. The solid-phase approach proved highly suitable to prepare substrates from low-level amounts of protein digests for phosphorylation-site determination by chemical-targeted proteolysis. The solid-phase protocol provides for a simple, robust, and efficient tool to prepare samples for phosphopeptide identification in MALDI mass maps of unfractionated protein digests, using standard equipment available in most biological laboratories. The use of a solid-phase analytical platform is expected to be readily expanded to prepare digest from O-glycosylated- and O-sulfonated proteins for mass spectrometry-based structural characterization. PMID:23997661

  3. First-principles interatomic potentials for transition-metal aluminides. III. Extension to ternary phase diagrams

    NASA Astrophysics Data System (ADS)

    Widom, Mike; Al-Lehyani, Ibrahim; Moriarty, John A.

    2000-08-01

    Modeling structural and mechanical properties of intermetallic compounds and alloys requires detailed knowledge of their interatomic interactions. The first two papers of this series [Phys. Rev. B 56, 7905 (1997); 58, 8967 (1998)] derived first-principles interatomic potentials for transition-metal (TM) aluminides using generalized pseudopotential theory (GPT). Those papers focused on binary alloys of aluminum with first-row transition metals and assessed the ability of GPT potentials to reproduce and elucidate the alloy phase diagrams of Al-Co and Al-Ni. This paper addresses the phase diagrams of the binary alloy Al-Cu and the ternary systems Al-Co-Cu and Al-Co-Ni, using GPT pair potentials calculated in the limit of vanishing transition-metal concentration. Despite this highly simplifying approximation, we find rough agreement with the known low-temperature phase diagrams, up to 50% total TM concentration provided the Co fraction is below 25%. Full composition-dependent potentials and many-body interactions would be required to correct deficiencies at higher Co concentration. Outside this troublesome region, the experimentally determined stable and metastable phases all lie on or near the convex hull of a scatter plot of energy versus composition. We verify, qualitatively, reported solubility ranges extending binary alloys into the ternary diagram in both Al-Co-Cu and Al-Co-Ni. Finally, we reproduce previously conjectured transition-metal positions in the decagonal quasicrystal phase.

  4. An improved procedure to prepare 3-methyl-4-nitroalkylenethylisoxazoles and their reaction under catalytic enantioselective Michael addition with nitromethane.

    PubMed

    Moccia, Maria; Wells, Robert J; Adamo, Mauro F A

    2015-02-21

    Herein, we describe a short synthesis of 3-methyl-4-nitro-5-alkylethenyl isoxazoles and their reactivity as Michael acceptors. The title compounds reacted with nitromethane under phase-transfer catalysis to provide highly enantioenriched adducts (up to 93% ee) which were then converted to the corresponding γ-nitroacids.

  5. Quantum Linear Systems Theory

    DTIC Science & Technology

    2013-02-15

    Matthew James, Andre Carvalho and Michael Hush completed some work analyzing cross-phase modulation using single photon quantum filtering techniques...ANU Michael Hush January – June, 2012, Postdoc, ANU Matthew R. James Professor, Australian National University Ian R. Petersen Professor...appear, IEEE Trans. Aut. Control., 2013. A. R. R. Carvalho, M. R. Hush , and M. R. James, “Cavity driven by a single photon: Conditional dynamics and

  6. Layer-by-layer growth of vertex graph of Penrose tiling

    NASA Astrophysics Data System (ADS)

    Shutov, A. V.; Maleev, A. V.

    2017-09-01

    The growth form for the vertex graph of Penrose tiling is found to be a regular decagon. The lower and upper bounds for this form, coinciding with it, are strictly proven. A fractal character of layer-by-layer growth is revealed for some subgraphs of the vertex graph of Penrose tiling.

  7. Part 3. a novel stereocontrolled, in situ, solution- and solid-phase, Aza Michael approach for high-throughput generation of tetrahydroaminoquinoline-derived natural-product-like architectures.

    PubMed

    Prakesch, Michael; Srivastava, Stuti; Leek, Donald M; Arya, Prabhat

    2006-01-01

    With the goal of rapidly accessing tetrahydroquinoline-based natural-product-like polycyclic architectures, herein, we report an unprecedented, in situ, stereocontrolled Aza Michael approach in solution and on the solid phase. The mild reaction conditions required to reach the desired target are highly attractive for the use of this method in library generation. To our knowledge, this approach has not been used before, and it opens a novel route leading to a wide variety of tetrahydroquinoline-derived bridged tricyclic derivatives.

  8. Diastereoselective auxiliary- and catalyst-controlled intramolecular aza-Michael reaction for the elaboration of enantioenriched 3-substituted isoindolinones. Application to the synthesis of a new pazinaclone analogue

    PubMed Central

    Sallio, Romain; Lebrun, Stéphane; Capet, Frédéric; Agbossou-Niedercorn, Francine

    2018-01-01

    A new asymmetric organocatalyzed intramolecular aza-Michael reaction by means of both a chiral auxiliary and a catalyst for stereocontrol is reported for the synthesis of optically active isoindolinones. A selected cinchoninium salt was used as phase-transfer catalyst in combination with a chiral nucleophile, a Michael acceptor and a base to provide 3-substituted isoindolinones in good yields and diastereomeric excesses. This methodology was applied to the asymmetric synthesis of a new pazinaclone analogue which is of interest in the field of benzodiazepine-receptor agonists. PMID:29623121

  9. Annual report to W-2188 multi-state research project "Characterizing Mass and Energy Transport at Different Vadose Zone Scales"

    USDA-ARS?s Scientific Manuscript database

    Results of our studies on soil water sensors were conveyed to manufacturers, including Acclima, Inc. and Decagon, Inc. Four invited presentations on soil water sensing for irrigation management were made to irrigation conferences in the Central and Southern High Plains (Nebraska and Texas). Eleven i...

  10. An Infiltration Exercise for Introductory Soil Science

    ERIC Educational Resources Information Center

    Barbarick, K. A.; Ippolito, J. A.; Butters, G.; Sorge, G. M.

    2005-01-01

    One of the largest challenges in teaching introductory soil science is explaining the dynamics of soil infiltration. To aid students in understanding the concept and to further engage them in active learning in the soils laboratory course, we developed an exercise using Decagon Mini-Disk Infiltrometers with a tension head (h[subscript o]) of 2 cm.…

  11. A Skeletal, Gas Phase, Finite Rate, Chemical Kinetics Mechanism for Modeling the Deflagration of Ammonium Perchlorate - Hydroxyl-Terminated Polybutadiene Composite Propellants

    DTIC Science & Technology

    2016-04-01

    the Deflagration of Ammonium Perchlorate— Hydroxyl-Terminated Polybutadiene Composite Propellants by Chiung-Chu Chen and Michael McQuaid...for Modeling the Deflagration of Ammonium Perchlorate— Hydroxyl-Terminated Polybutadiene Composite Propellants by Chiung-Chu Chen and Michael...Ammonium Perchlorate—Hydroxyl-Terminated Polybutadiene Composite Propellants 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6

  12. Synthesis, chemical reactivity as Michael acceptors, and biological potency of monocyclic cyanoenones, novel and highly potent anti-inflammatory and cytoprotective agents.

    PubMed

    Zheng, Suqing; Santosh Laxmi, Y R; David, Emilie; Dinkova-Kostova, Albena T; Shiavoni, Katherine H; Ren, Yanqing; Zheng, Ying; Trevino, Isaac; Bumeister, Ronald; Ojima, Iwao; Wigley, W Christian; Bliska, James B; Mierke, Dale F; Honda, Tadashi

    2012-05-24

    Novel monocyclic cyanoenones examined to date display unique features regarding chemical reactivity as Michael acceptors and biological potency. Remarkably, in some biological assays, the simple structure is more potent than pentacyclic triterpenoids (e.g., CDDO and bardoxolone methyl) and tricycles (e.g., TBE-31). Among monocyclic cyanoenones, 1 is a highly reactive Michael acceptor with thiol nucleophiles. Furthermore, an important feature of 1 is that its Michael addition is reversible. For the inhibition of NO production, 1 shows the highest potency. Notably, its potency is about three times higher than CDDO, whose methyl ester (bardoxolone methyl) is presently in phase III clinical trials. For the induction of NQO1, 1 also demonstrated the highest potency. These results suggest that the reactivity of these Michael acceptors is closely related to their biological potency. Interestingly, in LPS-stimulated macrophages, 1 causes apoptosis and inhibits secretion of TNF-α and IL-1β with potencies that are higher than those of bardoxolone methyl and TBE-31.

  13. Morphology of single inhalable particle inside public transit biodiesel fueled bus.

    PubMed

    Shandilya, Kaushik K; Kumar, Ashok

    2010-01-01

    In an urban-transit bus, fueled by biodiesel in Toledo, Ohio, single inhalable particle samples in October 2008 were collected and detected by scanning electron microscopy and energy dispersive X-ray spectrometry (SEM/EDS). Particle size analysis found bimodal distribution at 0.2 and 0.5 microm. The particle morphology was characterized by 14 different shape clusters: square, pentagon, hexagon, heptagon, octagon, nonagon, decagon, agglomerate, sphere, triangle, oblong, strip, line or stick, and unknown, by quantitative order. The square particles were common in the samples. Round and triangle particles are more, and pentagon, hexagon, heptagon, octagon, nonagon, decagon, strip, line or sticks are less. Agglomerate particles were found in abundance. The surface of most particles was coarse with a fractal edge that can provide a suitable chemical reaction bed in the polluted atmospheric environment. The three sorts of surface patterns of squares were smooth, semi-smooth, and coarse. The three sorts of square surface patterns represented the morphological characteristics of single inhalable particles in the air inside the bus in Toledo. The size and shape distribution results were compared to those obtained for a bus using ultra low sulfur diesel.

  14. Michael J. Fox and his Parkinson's disease.

    PubMed

    Kempster, Peter A

    2004-01-01

    Michael J. Fox was a popular and successful film and television comic actor who developed Parkinson's disease at the age of 29 years. His recently published book, Lucky Man, structured around the story of his Parkinson's disease, is an amusing, briskly paced yet introspective memoir that covers the first 40 years of his life. Although quite anecdotal, it contains interesting observations on the preclinical phase of the disorder, evolution of motor fluctuations, and tactics for pharmacological treatment. Copyright 2003 Movement Disorder Society

  15. Technical Communication Practices of Russian and U. S. Aerospace Engineers and Scientists

    DTIC Science & Technology

    1993-06-01

    Michael L. Keene University of Tennessee Knoxville, Tennessee Madelyn Flammia University of Central Flonda 93- 17927 Orlando, Florida ; ’ut’i i i l...Barclay. Michael L. Keene. Madelvn Flammia . and John M. Kennedy Abstract-As part of Phase 4 of the NASA/DoD Aerospace culture. organization, and...Russian survey participant respondents and 24% of the U.S. respondents indicated that PINELI I e, al TECHNICAL COMMUNICATION Of RL’hiAN AND L S

  16. Searching phase II enzymes inducers, from Michael acceptor-[1,2]dithiolethione hybrids, as cancer chemopreventive agents.

    PubMed

    Couto, Marcos; de Ovalle, Stefani; Cabrera, Mauricio; Cerecetto, Hugo; González, Mercedes

    2015-01-01

    Cancer chemoprevention involves the carcinogenic process prevention, delay or reverse by the administration of chemopreventive agents, which are able to suppress or block the carcinogen metabolic activation/formation. The increased activity of phase II detoxification enzymes such as quinone-reductase (QR) and glutation-S-transferase (GST) correlates with the protection against chemically-induced carcinogenesis. It has been shown that synthetic chalcones and 3H-[1,2]-dithiole-3-thiones promote expression of genes involved in chemoprevention. Herein, the induction of phase II enzymes by designed Michael acceptor-dithiolethione hybrids was studied. Hybrids 5 and 7 displayed the induction of quinone-reductase and glutation-S-transferase in vitro in the same order on the wild-type mouse-hepatoma Hepa 1c1c7 and on the aryl-hydrocarbon-nuclear-translocator (Arnt)-defective mutant BPrc1 cells indicating that 7 displays the best chemopreventive potential.

  17. Field-scale soil moisture space-time geostatistical modeling for complex Palouse landscapes in the inland Pacific Northwest

    NASA Astrophysics Data System (ADS)

    Chahal, M. K.; Brown, D. J.; Brooks, E. S.; Campbell, C.; Cobos, D. R.; Vierling, L. A.

    2012-12-01

    Estimating soil moisture content continuously over space and time using geo-statistical techniques supports the refinement of process-based watershed hydrology models and the application of soil process models (e.g. biogeochemical models predicting greenhouse gas fluxes) to complex landscapes. In this study, we model soil profile volumetric moisture content for five agricultural fields with loess soils in the Palouse region of Eastern Washington and Northern Idaho. Using a combination of stratification and space-filling techniques, we selected 42 representative and distributed measurement locations in the Cook Agronomy Farm (Pullman, WA) and 12 locations each in four additional grower fields that span the precipitation gradient across the Palouse. At each measurement location, soil moisture was measured on an hourly basis at five different depths (30, 60, 90, 120, and 150 cm) using Decagon 5-TE/5-TM soil moisture sensors (Decagon Devices, Pullman, WA, USA). This data was collected over three years for the Cook Agronomy Farm and one year for each of the grower fields. In addition to ordinary kriging, we explored the correlation of volumetric water content with external, spatially exhaustive indices derived from terrain models, optical remote sensing imagery, and proximal soil sensing data (electromagnetic induction and VisNIR penetrometer)

  18. CONTROLLED DIESEL EXPOSURES: INTER-PHASING HUMAN AND ANIMAL STUDIES AND THEIR USE IN THE RISK ASSESSMENT

    EPA Science Inventory

    Controlled diesel exposures: Inter-phasing human and animal studies and their use in the risk assessment process.
    Michael C. Madden, US EPA.

    Particulate matter (PM) has been reported to be associated with health effects (e.g., premature deaths, hospitalizations, lung ...

  19. Unique atom hyper-kagome order in Na4Ir3O8 and in low-symmetry spinel modifications.

    PubMed

    Talanov, V M; Shirokov, V B; Talanov, M V

    2015-05-01

    Group-theoretical and thermodynamic methods of the Landau theory of phase transitions are used to investigate the hyper-kagome atomic order in structures of ordered spinels and a spinel-like Na4Ir3O8 crystal. The formation of an atom hyper-kagome sublattice in Na4Ir3O8 is described theoretically on the basis of the archetype (hypothetical parent structure/phase) concept. The archetype structure of Na4Ir3O8 has a spinel-like structure (space group Fd\\bar 3m) and composition [Na1/2Ir3/2](16d)[Na3/2](16c)O(32e)4. The critical order parameter which induces hypothetical phase transition has been stated. It is shown that the derived structure of Na4Ir3O8 is formed as a result of the displacements of Na, Ir and O atoms, and ordering of Na, Ir and O atoms, ordering dxy, dxz, dyz orbitals as well. Ordering of all atoms takes place according to the type 1:3. Ir and Na atoms form an intriguing atom order: a network of corner-shared Ir triangles called a hyper-kagome lattice. The Ir atoms form nanoclusters which are named decagons. The existence of hyper-kagome lattices in six types of ordered spinel structures is predicted theoretically. The structure mechanisms of the formation of the predicted hyper-kagome atom order in some ordered spinel phases are established. For a number of cases typical diagrams of possible crystal phase states are built in the framework of the Landau theory of phase transitions. Thermodynamical conditions of hyper-kagome order formation are discussed by means of these diagrams. The proposed theory is in accordance with experimental data.

  20. Soil moisture monitoring in Candelaro basin, Southern Italy

    NASA Astrophysics Data System (ADS)

    Campana, C.; Gigante, V.; Iacobellis, V.

    2012-04-01

    The signature of the hydrologic regime can be investigated, in principle, by recognizing the main mechanisms of runoff generation that take place in the basin and affect the seasonal behavior or the rainfall-driven events. In this framework, besides the implementation of hydrological models, a crucial role should be played by direct observation of key state variables such as soil moisture at different depths and different distances from the river network. In fact, understanding hydrological systems is often limited by the frequency and spatial distribution of observations. Experimental catchments, which are field laboratories with long-term measurements of hydrological variables, are not only sources of data but also sources of knowledge. Wireless distributed sensing platforms are a key technology to address the need for overcoming field limitations such as conflicts between soil use and cable connections. A stand-alone wireless network system has been installed for continuous monitoring of soil water contents at multiple depths along a transect located in Celone basin (sub-basin of Candelaro basin in Puglia, Southern Italy). The transect consists of five verticals, each one having three soil water content sensors at multiple depths: 0,05 m, 0,6 m and 1,2 m below the ground level. The total length of the transect is 307 m and the average distance between the verticals is 77 m. The main elements of the instrumental system installed are: fifteen Decagon 10HS Soil Moisture Sensors, five Decagon Em50R Wireless Radio Data Loggers, one Rain gauge, one Decagon Data Station and one Campbell CR1000 Data Logger. Main advantages of the system as described and presented in this work are that installation of the wireless network system is fast and easy to use, data retrieval and monitoring information over large spatial scales can be obtained in (near) real-time mode and finally other type of sensors can be connected to the system, also offering wide potentials for future applications. First records of the wireless underground network system indicate the presence of interesting patterns in space-time variability of volumetric soil moisture content, that provide evidence of the combined process of vertical infiltration and lateral flow. ACKNOWLEDGEMENT The research in this work is supported by the MIRAGE FP7 project (Grant agreement n. 211732).

  1. Tactical Airspace Integration System Situation Awareness Integration Into the Cockpit: Phase 2

    DTIC Science & Technology

    2013-03-01

    ARL-TR-6371 March 2013 prepared by U.S. Army Research Laboratory Human Research and Engineering Directorate (AMCOM Field...Situation Awareness Integration Into the Cockpit: Phase II Michael Sage Jessee and Anthony Morris Human Research and Engineering Directorate, ARL...prepared by U.S. Army Research Laboratory Human Research and Engineering Directorate (AMCOM Field Element) Bldg 5400, Room C236

  2. Synthesis of a stationary phase based on silica modified with branched octadecyl groups by Michael addition and photoinduced thiol-yne click chemistry for the separation of basic compounds.

    PubMed

    Huang, Guang; Ou, Junjie; Wang, Hongwei; Ji, Yongsheng; Wan, Hao; Zhang, Zhang; Peng, Xiaojun; Zou, Hanfa

    2016-04-01

    A novel silica-based stationary phase with branched octadecyl groups was prepared by the sequential employment of the Michael addition reaction and photoinduced thiol-yne click chemistry with 3-aminopropyl-functionalized silica microspheres as the initial material. The resulting stationary phase denoted as SiO2 -N(C18)4 was characterized by elemental analysis, FTIR spectroscopy and Raman spectroscopy, demonstrating the existence of branched octadecyl groups in silica microspheres. The separations of benzene homologous compounds, acid compounds and amine analogues were conducted, demonstrating mixed-mode separation mechanism on SiO2 -N(C18)4 . Baseline separation of basic drugs mixture was acquired with the mobile phase of acetonitrile/H2 O (5%, v/v). SiO2 -N(C18)4 was further applied to separate Corydalis yanhusuo Wang water extracts, and more baseline separation peaks were obtained for SiO2 -N(C18)4 than those on Atlantis dC18 column. It can be expected that this new silica-based stationary phase will exhibit great potential in the analysis of basic compounds. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  3. Exploring Capabilities of Electrical Capacitance Tomography Sensor and Velocity Analysis of Two-Phase R-134A Flow Through a Sudden Expansion

    DTIC Science & Technology

    2017-05-01

    SUDDEN EXPANSION 5a. CONTRACT NUMBER In-house 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 62203F 6. AUTHOR(S) Joseph Michael Cronin 5d. PROJECT ...heat transfer in order to manage the ever-increasing airframe and engine heat loads. Two-phase liquid-vapor refrigerant systems are one solution for...were compared with pressure drop correlations. 15. SUBJECT TERMS thermal management , two-phase flow, flow visualization, electric capacitance

  4. Microgravity

    NASA Image and Video Library

    2000-06-05

    Prof. Kerneth Kelton of Washington University in St. Lous, MO, (L) and Dr. Michael Robinson of NASA's Marshall Space Flight Center (MSFC) examine a titanium-iron silicate (TiFeSiO)sample processed in MSFC's Electrostatic Levitator (ESL) Facility (background). Kelton is investigating undercooling of polytetrahedral phase-forming liquids.

  5. Identification and Quantification of Pesticides in Environmental Waters With Solid Phase Microextraction and Analysis Using Field-Portable Gas Chromatography-Mass Spectrometry

    DTIC Science & Technology

    2004-06-10

    Microextraction and Analysis using Field-Portable Gas Chromatography-Mass Spectrometry Name of Candidate: CPT Michael J. Nack...and Analysis using Field-Portable Gas Chromatography-Mass Spectrometry Beyond brief excerpts is with the permission of the copyright owner, and...Pesticides in Environmental Waters with Solid Phase Microextraction and Analysis using Field-Portable Gas Chromatography-Mass Spectrometry

  6. Travel Grants Benefit 120 Students

    NASA Astrophysics Data System (ADS)

    2008-12-01

    AGU is pleased to announce that 120 students from 21 countries will travel to the AGU Fall Meeting in San Francisco to present their research. The travel grants are made possible through the generosity of Exxon Mobil, Northrup Grumman, Elsevier, Sequoia Scientific, Li-Cor Biogeosciences, Cassidy Associates, Decagon Devices, RBR Ltd., Springer, Jamie A. Austin Jr., the Max Hammond Student Travel Endowment, and 157 AGU members. The number of grants for students to travel to the Fall Meeting represents an increase of four times from those given in the previous years.

  7. Quasicrystal structure and growth models: discussion of the status quo and the still open questions

    NASA Astrophysics Data System (ADS)

    Steurer, Walter

    2017-02-01

    Where are we now in quasicrystal (QC) research more than three decades after Dan Shechtman’s discovery? Do we fully understand the origin of quasiperiodicity, the formation, growth, thermodynamic stability, structure and properties of quasicrystals? First, I will shortly present the status quo, then I will address the still open questions, and identify potential focus areas for future research. Because of the limited space, I will focus on decagonal quasicrystals (DQCs); the status quo for research on icosahedral quasicrystals (IQCs) is comparable.

  8. A Stitch in Time Saves Nine: A Comprehensive Conflict Prevention Strategy

    DTIC Science & Technology

    2010-04-02

    prevention plan, has led to ad-hoc conflict prevention. 1 Charles F. Wald , "The Phase Zero Campaign," JFQ: Joint Force Quarterly, no. 43 (10...14. 24 Joint Chiefs of Staff, Joint Operations, 2008), IV 27-28. 25 Wald , The Phase Zero Campaign, 73. 26 Ibid., 73. 27 secure...Unconventional Threats and Capabilities. Testimony of Michael Lund and Dr. Lisa Schrich on the Roles of Non-Military Programs within a Comprehensive

  9. Organocatalytic aza-Michael/retro-aza-Michael reaction: pronounced chirality amplification in aza-Michael reaction and racemization via retro-aza-Michael reaction.

    PubMed

    Cai, Yong-Feng; Li, Li; Luo, Meng-Xian; Yang, Ke-Fang; Lai, Guo-Qiao; Jiang, Jian-Xiong; Xu, Li-Wen

    2011-05-01

    A detailed experimental investigation of an aza-Michael reaction of aniline and chalcone is presented. A series of Cinchona alkaloid-derived organocatalysts with different functional groups were prepared and used in the aza-Michael and retro-aza-Michael reaction. There was an interesting finding that a complete reversal of stereoselectivity when a benzoyl group was introduced to the cinchonine and cinchonidine. The chirality amplification vs. time proceeds in the quinine-derived organocatalyst containing silicon-based bulky group, QN-TBS, -catalyzed aza-Michael reaction under solvent-free conditions. In addition, we have demonstrated for the first time that racemization was occurred in suitable solvents under mild conditions due to retro-aza-Michael reaction of the Michael adduct of aniline with chalcone. These indicate the equilibrium of retro-aza-Michael reaction and aza-Michael reaction produce the happening of chirality amplification in aza-Michael reaction and racemization via retro-aza-Michael reaction under different conditions, which would be beneficial to the development of novel chiral catalysts for the aza-Michael reactions. Copyright © 2011 Wiley-Liss, Inc.

  10. Calibration procedures to test the feasibility of heated fiber optics for measuring soil water content in field conditions.

    NASA Astrophysics Data System (ADS)

    Benítez, Javier; Sayde, Chadi; Rodríguez Sinobas, Leonor; Sánchez, Raúl; Gil, María; Selker, John

    2013-04-01

    This research provides insights of the calibration procedures carried out at the agricultural field of La Nava de Arévalo (Spain). The suitability of the heat pulse theory applied to fiber optics for measuring soil water content, in field conditions, is here analyzed. In addition, it highlights the major findings obtained and the weakness to be addressed in future studies. Within a corn field, in a plot of 500 m2 of bare soil, 600 m of fiber optic cable (BruggSteal) were buried on a ziz-zag deployment at two depths, 30cm and 60cm. Various electrical heat pulses of 20W/m were applied to the stainless steel shield of the fiber optic cable during 2 minutes. The resulting thermal response was captured by means of Distributed Fiber Optic Temperature sensing (DFOT), within a spatial and temporal resolution up to 25 cm and 1 s, respectively. The soil thermal response was then correlated to the soil water content by using undisturbed soil samples and soil moisture sensors (Decagon ECHO 5TM). The process was also modeled by applying the numerical methods software Hydrus 2D. Also, the soil thermal properties were measured in situ by using a dual heat pulse probe (Decagon Kd2Pro). For an ongoing process, first results obtained show the suitability of heated fiber optics for measuring soil water content, in real field conditions. Also, they highlight the usefulness of Hydrus 2D as a complementary tool for calibration purposes and for reducing uncertainty in addressing soil spatial variability.

  11. An agronomic field-scale sensor network for monitoring soil water and temperature variation

    NASA Astrophysics Data System (ADS)

    Brown, D. J.; Gasch, C.; Brooks, E. S.; Huggins, D. R.; Campbell, C. S.; Cobos, D. R.

    2014-12-01

    Environmental sensor networks have been deployed in a variety of contexts to monitor plant, air, water and soil properties. To date, there have been relatively few such networks deployed to monitor dynamic soil properties in cropped fields. Here we report on experience with a distributed soil sensor network that has been deployed for seven years in a research farm with ongoing agronomic field operations. The Washington State University R. J. Cook Agronomy Farm (CAF), Pullman, WA, USA has recently been designated a United States Department of Agriculture (USDA) Long-Term Agro-Ecosystem Research (LTAR) site. In 2007, 12 geo-referenced locations at CAF were instrumented, then in 2009 this network was expended to 42 locations distributed across the 37-ha farm. At each of this locations, Decagon 5TE probes (Decagon Devices Inc., Pullman, WA, USA) were installed at five depths (30, 60, 90, 120, and 150 cm), with temperature and volumetric soil moisture content recorded hourly. Initially, data loggers were wirelessly connected to a data station that could be accessed through a cell connection, but due to the logistics of agronomic field operations, we later buried the dataloggers at each site and now periodically download data via local radio transmission. In this presentation, we share our experience with the installation, maintenance, calibration and data processing associated with an agronomic soil monitoring network. We also present highlights of data derived from this network, including seasonal fluctuations of soil temperature and volumetric water content at each depth, and how these measurements are influenced by crop type, soil properties, landscape position, and precipitation events.

  12. Biography for Michael Rossol | NREL

    Science.gov Websites

    Biography for Michael Rossol Michael Rossol Michael Rossol Resource Data Scientist Michael.Rossol @nrel.gov | 303-275-3680 Michael Rossol is a member of the Systems Modeling team within the Systems Modeling

  13. Aersol Jet Deposition of Geramic Thin Films for Electromechanical Applications

    DTIC Science & Technology

    2012-03-01

    Ethyl Cellulose (EC) were utilized as binder and plasticizer constituents. Inks were prepared by the addition of powders, to the combination of...0 NiO 0 0 0 0 0 0 34.6 LSM Disperbyk-111 Solsperse-3000 Dispex-A40 Ethyl Cellulose 0 0 0 0 0.21 0 0 0.56 0 0.21 0 0.56 0 0 0.21 0 0 0 0.56 0.21...of pattern filling was done by using a spiral fill (Fig 3d , e, f.). For this, a decagonal pattern was generated using AutoCAD® polyline segments

  14. Thermal Energy Storage in Phase Change Material.

    DTIC Science & Technology

    1982-03-01

    Graphs of the exnerimental results follow: tney are groupea in the tree categories: tube cross flow, ricked bed, and tube parallel flow. A. Tube Cross... Riordan , Michael, "Thermal Storage: A Rtsic Guile to the Ptate of the Art", Solar Age, Aril, 1978, P. 10. 5. Telkes, Maria, "Thermal Lner y Storage in

  15. Integrated Cognitive-neuroscience Architectures for Understanding Sensemaking (ICArUS): Overview of Test and Evaluation Materials

    DTIC Science & Technology

    2014-11-01

    Phase 2 than for Phase 1 ) in three components of T&E: a qualitative Neural Fidelity Assessment (NFA), a quantitative Cognitive Fidelity Assessment ( CFA ...Burns Craig Bonaceto Michael Fine Carsten Oertel November, 2014 MT R 1 4 04 0 9 MIT R E T E C H N IC A L R E P OR T...No. 0704-0188 Public reporting burden for the collection of information is estimated to average 1 hour per response, including the time for reviewing

  16. 76 FR 46801 - Modification of the Expiration Date for the National Pollutant Discharge Elimination System...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-03

    ... CONTACT: Alanna Conley or Michael Mitchell of the Stormwater and Nonpoint Source Section, Water Protection... are available at EPA Region 4's stormwater Web site at: http://www.epa.gov/region4/water/permits... Water Act (CWA) directs EPA to develop a phased approach to regulate stormwater discharges under the...

  17. Possible nucleus of the Bergman cluster in the Zn-Mg-Y alloy system

    NASA Astrophysics Data System (ADS)

    Nakayama, Kei; Nakagawa, Masaya; Koyama, Yasumasa

    2018-01-01

    To understand the formation of the Bergman cluster in the F-type icosahedral quasicrystal (IQ), crystallographic relations between the quasicrystal and the intermetallic-compound H and Zn23Y6 phases in the Zn-Mg-Y alloy system were investigated mainly by transmission electron microscopy. It was found that, although sample rotations of about 1° were required to obtain simple crystallographic relations, the orientation relationship was established among the cubic-Fm?m Zn23Y6 structure, the hexagonal-P63/mmc H structure and the F-type IQ; that is, [? 1 3]c // the five-fold axis in the IQ // N(2 ? 0)H, and [1 1 0]c // the two-fold axis in the IQ // N(0 5 ? 3)H, where N(h k m l)H means the normal direction of the (h k m l)H plane in the H structure. The correspondences between atomic positions in the Bergman cluster and in the Zn23Y6 structure and between those in the cluster and in the H structure were investigated on the basis of the established relationship. As a result, an assembly of six short-penetrated-decagonal columns was identified as an appropriate nucleus in the formation of the Bergman cluster from these two structures.

  18. Michael Ulsh | NREL

    Science.gov Websites

    Michael Ulsh Photo of Michael Ulsh Michael Ulsh Manufacturing R&D Project Lead Michael.Ulsh -line quality control, the study of the performance and durability effects of manufacturing defects, and lead for a multi-lab consortium on solution processing and roll-to-roll manufacturing, and is involved

  19. Evidence from x-ray and neutron powder diffraction patterns that the so-called icosahedral and decagonal quasicrystals of MnAl(6) and other alloys are twinned cubic crystals.

    PubMed

    Pauling, L

    1987-06-01

    It is shown that the x-ray powder diffraction patterns of rapidly quenched MnAl(6) and Mg(32)(Al,Zn)(49) and the neutron powder diffraction pattern of MnAl(6) are compatible with the proposed 820-atom primitive cubic structure [Pauling, L. (1987) Phys. Rev. Lett. 58, 365-368]. The values found for the edge of the unit cube are 23.365 A (x-ray) and 23.416 A (neutron) for MnAl(6) and 24.313 A (x-ray) for Mg(32)(Al,Zn)(49).

  20. Evidence from x-ray and neutron powder diffraction patterns that the so-called icosahedral and decagonal quasicrystals of MnAl6 and other alloys are twinned cubic crystals

    PubMed Central

    Pauling, Linus

    1987-01-01

    It is shown that the x-ray powder diffraction patterns of rapidly quenched MnAl6 and Mg32(Al,Zn)49 and the neutron powder diffraction pattern of MnAl6 are compatible with the proposed 820-atom primitive cubic structure [Pauling, L. (1987) Phys. Rev. Lett. 58, 365-368]. The values found for the edge of the unit cube are 23.365 Å (x-ray) and 23.416 Å (neutron) for MnAl6 and 24.313 Å (x-ray) for Mg32(Al,Zn)49. PMID:16593841

  1. Structure of the orthorhombic form of Mn(2)Al(7), Fe(2)Al(7), and (Mn(0.7)Fe(0.3))(2)Al(7) that by twinning produces grains with decagonal point-group symmetry.

    PubMed

    Pauling, L

    1988-04-01

    Analysis of electron diffraction photographs of grains of Mn(2)Al(7), Fe(2)Al(7), and (Mn(0.7)Fe(0.3))(2)Al(7) leads to the conclusion that they are 5-fold twins of a 1664-atom orthorhombic crystal with a = 32.86 A, b = 31.23 A, and c = 24.80 A and with 16 icosahedral clusters of 104 atoms in positions shifted by small amounts from those of the cubic beta-tungsten structure.

  2. Structure of the orthorhombic form of Mn2Al7, Fe2Al7, and (Mn0.7Fe0.3)2Al7 that by twinning produces grains with decagonal point-group symmetry

    PubMed Central

    Pauling, Linus

    1988-01-01

    Analysis of electron diffraction photographs of grains of Mn2Al7, Fe2Al7, and (Mn0.7Fe0.3)2Al7 leads to the conclusion that they are 5-fold twins of a 1664-atom orthorhombic crystal with a = 32.86 Å, b = 31.23 Å, and c = 24.80 Å and with 16 icosahedral clusters of 104 atoms in positions shifted by small amounts from those of the cubic β-tungsten structure. PMID:16593921

  3. Global Military Operating Environments (GMOE) Phase I: Linking Natural Environments, International Security, and Military Operations

    DTIC Science & Technology

    2013-01-30

    example from the Negev Desert, Israel, Journal of Geophysical Research, (05 2009): 1. doi: 01/14/2013 5.00 Michael Young, Eric McDonald, Jianting Zhu... radiation (incoming – reflected) x Solar Radiation Eppley Incoming solar radiation x Surface temperature IR Apogee Continuous surface...and electrical properties (dielectric permittivity and electrical conductivity). Additional measurements of solar radiation (four components), air

  4. Development of Job Aids for Instructional Systems Development

    DTIC Science & Technology

    1981-02-01

    assistance during the needs assessment and evaluation phases: Dr. William Ketner, Mr. Earl Duncan, Mr. Richard Arnold, Mr. John Meyers, Ms. Doris...Lakeman, Mr, Dan Danilovich, Ms. Yvonne Waldin and Mr. Richard Eberl. Ms. Jean Farrell and Mr. Michael Hillelsohn of HumRRO also contributed to this effort...Commandant for Educational Technology Mr. Earl Duncan, Education Specialist, Educational Technology Division Mr. Richard Arnold, Education Specialist

  5. Racemic synthesis and solid phase peptide synthesis application of the chimeric valine/leucine derivative 2-amino-3,3,4-trimethyl-pentanoic acid.

    PubMed

    Pelà, M; Del Zoppo, L; Allegri, L; Marzola, E; Ruzza, C; Calo, G; Perissutti, E; Frecentese, F; Salvadori, S; Guerrini, R

    2014-07-01

    The synthesis of non natural amino acid 2-amino-3,3,4-trimethyl-pentanoic acid (Ipv) ready for solid phase peptide synthesis has been developed. Copper (I) chloride Michael addition, followed by a Curtius rearrangement are the key steps for the lpv synthesis. The racemic valine/leucine chimeric amino acid was then successfully inserted in position 5 of neuropeptide S (NPS) and the diastereomeric mixture separated by reverse phase HPLC. The two diastereomeric NPS derivatives were tested for intracellular calcium mobilization using HEK293 cells stably expressing the mouse NPS receptor where they behaved as partial agonist and pure antagonist.

  6. 76 FR 55904 - Michael J. Donahue; Notice of Termination of Exemption By Implied Surrender and Soliciting...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-09

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project No. 6649-008] Michael J.... Date Initiated: September 1, 2011. d. Exemptee: Michael J. Donahue. e. Name and Location of Project.... Initiated Pursuant to: 18 CFR 4.106. g. Exemptee Contact Information: Mr. Michael J. Donahue, Route 3, Box...

  7. 76 FR 58264 - Michael J. Donahue; Notice of Termination of Exemption by Implied Surrender and Soliciting...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-20

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project No. 6649-008] Michael J.... Date Initiated: September 13, 2011. d. Exemptee: Michael J. Donahue. e. Name and Location of Project.... Initiated Pursuant to: 18 CFR 4.106. g. Exemptee Contact Information: Mr. Michael J. Donahue, Route 3, Box...

  8. 75 FR 62635 - Proposed Information Collection (Patient Satisfaction Survey Michael E. DeBakey Home Care Program...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-12

    ... Collection (Patient Satisfaction Survey Michael E. DeBakey Home Care Program) Activity: Comment Request... determine patients' satisfaction with services provided by or through the Michael E. DeBakey Home Care...: Patient Satisfaction Survey Michael E. DeBakey Home Care Program, VA Form 10-0476. OMB Control Number...

  9. 77 FR 69550 - Proposed Information Collection (Patient Satisfaction Survey Michael E. DeBakey Home Care Program...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-19

    ... (Patient Satisfaction Survey Michael E. DeBakey Home Care Program) Activity: Comment Request AGENCY... information needed to determine patients' satisfaction with services provided by or through the Michael E...: Patient Satisfaction Survey Michael E. DeBakey Home Care Program, VA Form 10-0476. OMB Control Number...

  10. Robust Adaptive Flight Control Design of Air-breathing Hypersonic Vehicles

    DTIC Science & Technology

    2016-12-07

    dynamic inversion controller design for a non -minimum phase hypersonic vehicle is derived by Kuipers et al. [2008]. Moreover, integrated guidance and...stabilization time for inner loop variables is lesser than the intermediate loop variables because of the three-loop-control design methodology . The control...adaptive design . Control Engineering Practice, 2016. Michael A Bolender and David B Doman. A non -linear model for the longitudinal dynamics of a

  11. Evaluation of GPS Coverage for the X-33 Michael-6 Trajectory

    NASA Technical Reports Server (NTRS)

    Lundberg, John B.

    1998-01-01

    The onboard navigational system for the X-33 test flights will be based on the use of measurements collected from the Embedded Global Positioning System (GPS)/INS system. Some of the factors which will affect the quality of the GPS contribution to the navigational solution will be the number of pseudorange measurements collected at any instant in time, the distribution of the GPS satellites within the field of view, and the inherent noise level of the GPS receiver. The distribution of GPS satellites within the field of view of the receiver's antenna will depend on the receiver's position, the time of day, pointing direction of the antenna, and the effective cone angle of the antenna. The number of pseudorange measurements collected will depend upon these factors as well as the time required to lock onto a GPS satellite signal once the GPS satellite comes into the field of view of the antenna and the number of available receiver channels. The objective of this study is to evaluate the GPS coverage resulting from the proposed antenna pointing directions, the proposed antenna cone angles, and the effects due to the time of day for the X-33 Michael-6 trajectory from launch at Edwards AFB, California, to the start of the Terminal Area Energy Management (TAEM) phase on approach to Michael AAF, Utah.

  12. Maniac Talk - Michael Mishchenko

    NASA Image and Video Library

    2015-01-26

    Michael Mishchenko Maniac Lecture, January 26, 2015 NASA climate scientist Dr. Michael I. Mishchenko presented a Maniac Talk entitled "How much first-principle physics do we need in remote-sensing and atmospheric-radiation research." Michael explained his skepticism and how it has shaped his contributions to the disciplines of electromagnetic scattering, radiative transfer, and remote sensing, which have found widespread use.

  13. 77 FR 67020 - Performance Review Board Appointments

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-08

    ..., Tommy Beck, Richard Belin, Alletta Berrigan, Michael Black, Michael Black, Steven Blanchard, Mary Josie..., Robert Reidenbach, Dennis Reynolds, Michael Rice, Bryan Roberson, Edwin Rountree, Carl Russ, David...

  14. Documentation in a Software Maintenance Environment.

    DTIC Science & Technology

    1987-08-28

    Michael Jackson Diagrams 0...8217 ." " . ." ." ""’, " , "" " - . -’" ,," ’" " " "’" d t Review of Documentation Techniques Michael Jackson Diagrams Michael Jackson diagrams show data...coupling and cohesion. Logic is not represented in this technique, which thus is of limited value. Advantages: Michael Jackson diagrams are similar

  15. Atomistic simulation of frictional anisotropy on quasicrystal approximant surfaces

    DOE PAGES

    Ye, Zhijiang; Martini, Ashlie; Thiel, Patricia; ...

    2016-06-23

    J. Y. Park et al. [Science 309, 1354 (2005)] have reported eight times greater atomic-scale friction in the periodic than in the quasiperiodic direction on the twofold face of a decagonal Al-Ni-Co quasicrystal. Here we present results of molecular-dynamics simulations intended to elucidate mechanisms behind this giant frictional anisotropy. Simulations of a bare atomic-force-microscope tip on several model substrates and under a variety of conditions failed to reproduce experimental results. On the other hand, including the experimental passivation of the tip with chains of hexadecane thiol, we reproduce qualitatively the experimental anisotropy in friction, finding evidence for entrainment of themore » organic chains in surface furrows parallel to the periodic direction.« less

  16. Synthesis and Evaluation of Novel RSK Inhibitors in a Living Human Breast Model

    DTIC Science & Technology

    2012-07-01

    surprising. However, MCF7 cells express aldo-keto reductases ( AKRs ), well known to be Phase I metabolizing enzymes for a variety of drugs bearing...Inhibitors in a Living Human Breast Model PRINCIPAL INVESTIGATOR: Dr. Michael Hilinski CONTRACTING ORGANIZATION: The University of...that notwithstanding any other provision of law, no person shall be subject to any penalty for failing to comply with a collection of information if it

  17. Framing the Cultural Training Landscape: Phase I Findings

    DTIC Science & Technology

    2008-12-01

    The DoD Dictionary of Military and Associated Terms master database is managed by the Joint Doctrine Division, J-7, Joint Staff, and was amended...officers, into classrooms to talk about where they come from and who they are, helps the students learn about everything from their native food and... Master Sergeant Michael Beemer indicates that they are regularly contacted by individuals who will be deploying for a tour as an advisor who feel they

  18. Optoelectronic Device Integration in Silicon (OpSIS)

    DTIC Science & Technology

    2015-10-26

    silicon-on-insulator," Opt. Express 22, 17872-17879 (2014) Y. Yang, C. Galland, Y. Liu, K. Tan , R. Ding, Q. Li, K. Bergman, T. Baehr-Jones, M...Ding, Ran; Liu, Yang; Ayazi, Ali; Pinguet, Thierry; Harris, Nicholas C; Streshinsky, Matt; Lee, Poshen; Zhang, Yi; Lim, Andy Eu-Jin; “Ultralow drive...Ding, Ran; Harris, Nicholas C; Baehr-Jones, Tom; Hochberg, Michael; “Broadband on-chip optical non-reciprocity using phase modulators” Optics express

  19. 4. Photocopy of inkandwatercolor drawing (from St. Michael's Church) Rambusch, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. Photocopy of ink-and-watercolor drawing (from St. Michael's Church) Rambusch, illustrator ca. 1932-37 INTERIOR, LOOKING NORTHEAST - St. Michael's Catholic Church, 519 East Third Street, Madison, Jefferson County, IN

  20. Michael J. Fox: Spurring Research on Parkinson's

    MedlinePlus

    ... on. Feature: Parkinson's Disease Michael J. Fox: Spurring Research on Parkinson's Past Issues / Winter 2014 Table of ... founded the Michael J. Fox Foundation for Parkinson's Research in the year 2000. Photo courtesy of Shutterstock " ...

  1. Dignital Biological Converter

    DTIC Science & Technology

    2014-01-03

    DARPA Contracting Officer: Michael Blackstone Submitted by: HEATHER GOUVIS Synthetic Genomics, Inc. 11149 NORTH TORREY PINES RD LA JOLLA, CA...Contracting Officer Representative (COR) Email: salit@nist.gov Michael Blackstone DARPA Contracting Officer Michael.Blackstone@darpa.mil DARPA

  2. Biomimetically inspired asymmetric total synthesis of (+)-19-dehydroxyl arisandilactone A

    NASA Astrophysics Data System (ADS)

    Han, Yi-Xin; Jiang, Yan-Long; Li, Yong; Yu, Hai-Xin; Tong, Bing-Qi; Niu, Zhe; Zhou, Shi-Jie; Liu, Song; Lan, Yu; Chen, Jia-Hua; Yang, Zhen

    2017-01-01

    Complex natural products are a proven and rich source of disease-modulating drugs and of efficient tools for the study of chemical biology and drug discovery. The architectures of complex natural products are generally considered to represent significant barriers to efficient chemical synthesis. Here we describe a concise and efficient asymmetric synthesis of 19-dehydroxyl arisandilactone A--which belongs to a family of architecturally unique, highly oxygenated nortriterpenoids isolated from the medicinal plant Schisandra arisanensis. This synthesis takes place by means of a homo-Michael reaction, a tandem retro-Michael/Michael reaction, and Cu-catalysed intramolecular cyclopropanation as key steps. The proposed mechanisms for the homo-Michael and tandem retro-Michael/Michael reactions are supported by density functional theory (DFT) calculation. The developed chemistry may find application for the synthesis of its other family members of Schisandraceae nortriterpenoids.

  3. Catalytic asymmetric Michael reactions promoted by a lithium-free lanthanum-BINOL complex

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sasai, Hiroaki; Arai, Takayoshi; Shibasaki, Masakatsu

    1994-02-23

    In this communication, we report about a new lithium-free BINOL-lanthanum complex, which is quite effective in catalytic asymmetric Michael reaction. We have succeeded in developing effective asymmetric base catalysts, in particular, asymmetric ester enolate catalysts for asymmetric Michael reactions. Two asymmetric lanthanum complexes are now available, namely, BINOL-lanthanum-lithium complex, which is quite effective in catalytic asymmetric nitrosaldol reactions, and a new lithium-free BINOL-lanthanum ester enolate complex, that is very effective in catalytic asymmetric Michael reactions. The two complexes complement each other in their ability to catalyze asymmetric nitroaldol and asymmetric Michael reactions. 14 refs., 1 fig., 2 tabs.

  4. Chain Dynamic Formulations for Multibody System Tracked Vehicles (Preprint)

    DTIC Science & Technology

    2013-03-06

    Michael Wallin 1 Ahmed K. Aboubakr 1 Paramsothy Jayakumar 2 Michael D. Letherwood 2 Ashraf Hamed 1 Ahmed A. Shabana 1...5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Michael Wallin; Ahmed Aboubakr; Paramsothy Jayakumar ; Michael Letherwood; Ashraf Hamed 5d...Taylor & Francis/CRC, Boca Raton, Florida. 16. Shabana, A. A., Hamed, A. M., Mohamed, A. A., Jayakumar , P., and Letherwood, M. D. 2012, “Use of B

  5. Installation Restoration Program. Phase I. Records Search, Plattsburgh AFB, New York

    DTIC Science & Technology

    1985-04-01

    Storage Area (WSA) drainage to the Salmon River, the POL and housing area drainage to Lake Champlaln, and the golf course streams and ponds drain...Sanitary Engineering; 2. Michael A. Zapkln, Project Director, M. Eng. Environmental Engineering and M.S. Biology - Team Chief and Ecologlst; 3. Andrew...college courses were offered to World War II veterans. This center became part of the State University system in 1950 and was known as Champlain College

  6. Fyn: A Key Regulator of Metastasis in Prostate Cancer

    DTIC Science & Technology

    2013-06-01

    CSMC with Drs. Leland Chung, Michael Freeman, Neil Bhowmick, Beatrice Knudsen, Hyung Kim, Dolores DiVizio, Howard Sandler, and Stuart Holden... Heath EI, Posadas EM, Yu EY, Harrison MR, Bruce JY, Cho SY, Wilding GE, Fetterly GJ, Hangauer DG, Kwan MF, Dyster LM, Carducci MA. A phase 2 study of...assays of Fyn and Met Neil Bhowmick, PhD- cysteine as a biomarker in PCa (forthcoming clinical trial) Beatrice Knudsen, MD-PhD- MET/SRC/FYN

  7. Installation Restoration Program. Phase 2. Confirmation Quantification. Stage 2 for MacDill Air Force Base, Florida. Volume 2

    DTIC Science & Technology

    1988-07-22

    Inc. of Savannah, Georgia and Tallahassee, Florida provided analytical services. Michael Newberry, Captain USAF, and Jeff Mason, 2d LT., USAF, from...2803-19 AG AP6 ST;- ES Ci eit 2803-20 A? APC S -2 ES 23033-23 AG .AF6 SD-S 2803-22 AC AP6 SD-4 E.> PARAMIETER 280u- .y 2&u r 23-2: 2803-22 Bezo (g.h.1

  8. Facile construction of macroporous hybrid monoliths via thiol-methacrylate Michael addition click reaction for capillary liquid chromatography.

    PubMed

    Lin, Hui; Ou, Junjie; Liu, Zhongshan; Wang, Hongwei; Dong, Jing; Zou, Hanfa

    2015-01-30

    A facile approach based on thiol-methacrylate Michael addition click reaction was developed for construction of porous hybrid monolithic materials. Three hybrid monoliths were prepared via thiol-methacrylate click polymerization by using methacrylate-polyhedral oligomeric silsesquioxane (POSS) (cage mixture, n=8, 10, 12, POSS-MA) and three multi-thiol crosslinkers, 1,6-hexanedithiol (HDT), trimethylolpropane tris(3-mercaptopropionate) (TPTM) and pentaerythritol tetrakis(3-mercaptopropionate) (PTM), respectively, in the presence of porogenic solvents (n-propanol and PEG 200) and a catalyst (dimethylphenylphosphine, DMPP). The obtained monoliths possessed high thermal and chemical stabilities. Besides, they all exhibited high column efficiencies and excellent separation abilities in capillary liquid chromatography (cLC). The highest column efficiency could reach ca. 195,000N/m for butylbenzene on the monolith prepared with POSS-MA and TPTM (monolith POSS-TPTM) in reversed-phase (RP) mode at 0.64mm/s. Good chromatographic performance were all achieved in the separations of polycyclic aromatic hydrocarbons (PAHs), phenols, anilines, EPA 610 as well as bovine serum albumin (BSA) digest. The high column efficiencies in the range of 51,400-117,000N/m (achieved on the monolith POSS-PTM in RP mode) convincingly demonstrated the high separation abilities of these thiol-methacrylate based hybrid monoliths. All the results demonstrated the feasibility of the phosphines catalyzed thiol-methacrylate Michael addition click reaction in fabrication of monolithic columns with high efficiency for cLC applications. Copyright © 2014 Elsevier B.V. All rights reserved.

  9. Michael E. Himmel | NREL

    Science.gov Websites

    E. Himmel Photo of Michael E. Himmel Michael Himmel Senior Research Fellow I-Molecular Biology ;Towards a molecular-level theory of carbohydrate processivity," Curr. Opinion Biotechnol. (2014 University, Department of Biochem. & Molecular Biol., Distinguished Alumnus (2014) Battelle Memorial

  10. 78 FR 42748 - Virginia Resource Advisory Committee Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-17

    ... each meeting, contact: Michael Williams, Public Affairs Specialist, Supervisor's Office, 540-265-5173... building in order to view comments. FOR FURTHER INFORMATION CONTACT: Michael Williams, Public Affairs... for time for oral comments must be sent to Michael Williams, Public Affairs Specialist, George...

  11. Synthesis of Triazole Derivatives of Levoglucosenone As Promising Anticancer Agents: Effective Exploration of the Chemical Space through retro-aza-Michael//aza-Michael Isomerizations.

    PubMed

    Tsai, Yi-Hsuan; Borini Etichetti, Carla M; Di Benedetto, Carolina; Girardini, Javier E; Martins, Felipe Terra; Spanevello, Rolando A; Suárez, Alejandra G; Sarotti, Ariel M

    2018-04-06

    The design and synthesis of biomass-derived triazoles and the in vitro evaluation as potential anticancer agents are described. The discovery of base-catalyzed retro-aza-Michael//aza-Michael isomerizations allowed the exploration of the chemical space by affording novel types of triazoles, difficult to obtain otherwise. Following this strategy, 2,4-disubstituted 1,2,3-triazoles could be efficiently obtained from the corresponding 1,4-disubstituted analogues.

  12. Surface Modified Particles By Multi-Step Michael-Type Addition And Process For The Preparation Thereof

    DOEpatents

    Cook, Ronald Lee; Elliott, Brian John; Luebben, Silvia DeVito; Myers, Andrew William; Smith, Bryan Matthew

    2005-05-03

    A new class of surface modified particles and a multi-step Michael-type addition surface modification process for the preparation of the same is provided. The multi-step Michael-type addition surface modification process involves two or more reactions to compatibilize particles with various host systems and/or to provide the particles with particular chemical reactivities. The initial step comprises the attachment of a small organic compound to the surface of the inorganic particle. The subsequent steps attach additional compounds to the previously attached organic compounds through reactive organic linking groups. Specifically, these reactive groups are activated carbon—carbon pi bonds and carbon and non-carbon nucleophiles that react via Michael or Michael-type additions.

  13. Generation of oculomotor images during tasks requiring visual recognition of polygons.

    PubMed

    Olivier, G; de Mendoza, J L

    2001-06-01

    This paper concerns the contribution of mentally simulated ocular exploration to generation of a visual mental image. In Exp. 1, repeated exploration of the outlines of an irregular decagon allowed an incidental learning of the shape. Analyses showed subjects memorized their ocular movements rather than the polygon. In Exp. 2, exploration of a reversible figure such as a Necker cube varied in opposite directions. Then, both perspective possibilities are presented. The perspective the subjects recognized depended on the way they explored the ambiguous figure. In both experiments, during recognition the subjects recalled a visual mental image of the polygon they compared with the different polygons proposed for recognition. To interpret the data, hypotheses concerning common processes underlying both motor intention of ocular movements and generation of a visual image are suggested.

  14. The mechanical design of hybrid graphene/boron nitride nanotransistors: Geometry and interface effects

    NASA Astrophysics Data System (ADS)

    Einalipour Eshkalak, Kasra; Sadeghzadeh, Sadegh; Jalaly, Maisam

    2018-02-01

    From electronic point of view, graphene resembles a metal or semi-metal and boron nitride is a dielectric material (band gap = 5.9 eV). Hybridization of these two materials opens band gap of the graphene which has expansive applications in field-effect graphene transistors. In this paper, the effect of the interface structure on the mechanical properties of a hybrid graphene/boron nitride was studied. Young's modulus, fracture strain and tensile strength of the models were simulated. Three likely types (hexagonal, octagonal and decagonal) were found for the interface of hybrid sheet after relaxation. Although Csbnd B bonds at the interface were indicated to result in more promising electrical properties, nitrogen atoms are better choice for bonding to carbon for mechanical applications.

  15. 76 FR 10352 - Keyser, Michael J.; Notice of Filing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-24

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. ID-6495-000] Keyser, Michael J.; Notice of Filing Take notice that on February 15, 2011, Michael J. Keyser submitted for filing, an application for authority to hold interlocking positions, pursuant to section 305(b) of the...

  16. Method for promoting Michael addition reactions

    DOEpatents

    Shah, Pankaj V.; Vietti, David E.; Whitman, David William

    2010-09-21

    Homogeneously dispersed solid reaction promoters having an average particle size from 0.01 .mu.m to 500 .mu.m are disclosed for preparing curable mixtures of at least one Michael donor and at least one Michael acceptor. The resulting curable mixtures are useful as coatings, adhesives, sealants and elastomers.

  17. Vietnam Head Injury Study - Phase III: A 30-Year Post-Injury Follow-Up Study

    DTIC Science & Technology

    2007-08-01

    Michael Koenigs1, Edward D. Huey1, Vanessa Raymont1,2, Bobby Cheon2, Jeffrey Solomon3, Eric M. Wassermann1, & Jordan Grafman1 1Cognitive Neuroscience...Currently, Dr. Vanessa Raymont and colleagues are about to submit a manuscript to the journal Brain entitled, “Demographic, Structural and Genetic...PENETRATING HEAD INJURY Vanessa Raymont1&2, Amanda Greathouse1&2, Katherine Reding1&2, Robert Lipsky3, Andres Salazar2, and Jordan Grafman2* 1

  18. CREW TRAINING - STS-33/51-L

    NASA Image and Video Library

    1985-08-09

    S85-44507 (October 1985) --- Sharon Christa McAuliffe, a teacher from Concord, New Hampshire, trains for the January 1986 mission of the space shuttle Challenger in the Johnson Space Center’s shuttle mission simulator (SMS). Learning about the overall spacecraft systems, McAuliffe is pictured here in the pilot’s station. For actual launch and landing phases, the Teacher-in-Space Project payload specialist would sit on the middeck. The photograph was taken by Michael O’Brien of Life Magazine. Photo credit: NASA

  19. Doing It All: Michael Sullivan--Weeks Public Library, NH

    ERIC Educational Resources Information Center

    Library Journal, 2005

    2005-01-01

    Michael Sullivan is a juggler--not a metaphorical one, a real one. He's also a library director, storyteller, competitive chess player, poet, speaker, and former children's librarian who continues to work with the kids in his community. This article summarizes the accomplishments and work of Michael Sullivan.

  20. Michael J. Meaney: Award for Distinguished Scientific Contributions

    ERIC Educational Resources Information Center

    American Psychologist, 2012

    2012-01-01

    Presents Michael J. Meaney as one of the winners of the American Psychological Association's Award for Distinguished Scientific Contributions (2012). Michael J. Meaney has taken the phenomenon of "handling" of newborn rats and opened a new area of investigation that has given new meaning to epigenetics via his work demonstrating transgenerational…

  1. Jack Michael's Motivation

    ERIC Educational Resources Information Center

    Miguel, Caio F.

    2013-01-01

    Among many of Jack Michael's contributions to the field of behavior analysis is his behavioral account of motivation. This paper focuses on the concept of "motivating operation" (MO) by outlining its development from Skinner's (1938) notion of "drive." Conceptually, Michael's term helped us change our focus on…

  2. 75 FR 22436 - Michael Williams-Control Exemption-St. Maries River Railroad, Inc.

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-28

    ... DEPARTMENT OF TRANSPORTATION Surface Transportation Board [Docket No. FD 35365] Michael Williams-Control Exemption-St. Maries River Railroad, Inc. Michael Williams (applicant),\\1\\ a noncarrier, has filed a verified notice of exemption to acquire control of St. Maries River Railroad, Inc. (STMA), a Class...

  3. Studying Teachers and Schools: Michael Pressley's Legacy and Directions for Future Research

    ERIC Educational Resources Information Center

    Mohan, Lindsey; Lundeberg, Mary A.; Reffitt, Kelly

    2008-01-01

    Much of Michael Pressley's work during the past decade focused on the nature of highly effective, engaging literacy instruction. Michael Pressley believed that studying effective teachers and schools had the potential to influence more engaging and effective teaching, especially in underresourced schools. First, we describe the grounded…

  4. Language and Intercultural Education: An Interview with Michael Byram

    ERIC Educational Resources Information Center

    Porto, Melina

    2013-01-01

    This article reports an interview with Michael Byram, Professor Emeritus, University of Durham in the United Kingdom, during his visit to Argentina in September 2011. Michael Byram is one of the main international referents in intercultural education. The interview addresses issues such as language education, intercultural and citizenship…

  5. Racemic hemiacetals as oxygen-centered pronucleophiles triggering cascade 1,4-addition/Michael reaction through dynamic kinetic resolution under iminium catalysis. Development and mechanistic insights† †Electronic supplementary information (ESI) available: Detailed experimental procedures and characterization of all new compounds, including copies of NMR spectra and HPLC chromatograms traces, computational details and Cartesian coordinates of all stationary points. CCDC 1525188 (4l), 1525189 (6a) and 1525190 (9a). For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c7sc00009j Click here for additional data file. Click here for additional data file.

    PubMed Central

    Orue, Ane; Uria, Uxue; Roca-López, David; Delso, Ignacio; Reyes, Efraím; Carrillo, Luisa

    2017-01-01

    2-Hydroxydihydropyran-5-ones behave as excellent polyfunctional reagents able to react with enals through oxa-Michael/Michael process cascade under the combination of iminium and enamine catalysis. These racemic hemiacetalic compounds are used as unconventional O-pronucleophiles in the initial oxa-Michael reaction, also leading to the formation of a single stereoisomer under a dynamic kinetic resolution (DKR) process. Importantly, by using β-aryl or β-alkyl substituted α,β-unsaturated substrates as initial Michael acceptors either kinetically or thermodynamically controlled diastereoisomers were formed with high stereoselection through the careful selection of the reaction conditions. Finally, a complete experimental and computational study confirmed the initially proposed DKR process during the catalytic oxa-Michael/Michael cascade reaction and also explained the kinetic/thermodynamic pathway operating in each case. PMID:28451356

  6. 78 FR 2391 - CAlifornians for Renewable Energy, Inc., Michael E. Boyd, Robert M. Sarvey v. Pacific Gas and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-11

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. RP13-436-000] CAlifornians for Renewable Energy, Inc., Michael E. Boyd, Robert M. Sarvey v. Pacific Gas and Electric Company... Energy Regulatory Commission (FERC); CAlifornians for Renewable Energy, Inc., Michael E. Boyd, and Robert...

  7. Interview with Michael Apple: The Biography of a Public Intellectual

    ERIC Educational Resources Information Center

    Peters, Michael A.

    2015-01-01

    Michael W. Apple is the John Bascom Professor of Curriculum and Instruction and Educational Policy Studies in the Departments of Curriculum and Instruction (CI) and Educational Policy Studies (EPS) at the University of Wisconsin-Madison School of Education where he has taught since 1970. Michael Apple is one of the foremost educational theorists…

  8. Markets, Marx, Modernity and Mathematics Education: A Response to Michael Apple.

    ERIC Educational Resources Information Center

    Gates, Peter

    This paper is a response to Michael Apple's paper, "What Postmodernists Forget: Cultural Capital and Official Knowledge." The paper advocates Michael's identification of the current dangers and processes of the growth of new right ideologies in the development of subjectivity, society, and education. The differences in success in the education…

  9. 77 FR 61596 - Wheatley, Michael I.; Garrison, Drummond E.; Notice of Filing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-10

    ...] Wheatley, Michael I.; Garrison, Drummond E.; Notice of Filing Take notice that on September 28, 2012, Michael I. Wheatley and Drummond E. Garrison submitted for filing, an application for authority to hold... the ``eFiling'' link at http://www.ferc.gov . Persons unable to file electronically should submit an...

  10. 76 FR 624 - Proposed Information Collection (Patient Satisfaction Survey Michael E. DeBakey Home Care Program...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-05

    ... Collection (Patient Satisfaction Survey Michael E. DeBakey Home Care Program) Activity: Comment Request... Form 10-0476).'' SUPPLEMENTARY INFORMATION: Title: Patient Satisfaction Survey Michael E. DeBakey Home... satisfaction with the quality of services/care provided by home care program staff. An agency may not conduct...

  11. NASA Catches Tropical Storm Leslie and Hurricane Michael in the Atlantic

    NASA Image and Video Library

    2017-12-08

    This visible image of Tropical Storm Leslie and Hurricane Michael was taken by the MODIS instrument aboard both NASA's Aqua and Terra satellites on Sept. 9 at 12:50 p.m. EDT. Credit: NASA Goddard/MODIS Rapid Response Team -- Satellite images from two NASA satellites were combined to create a full picture of Tropical Storm Leslie and Hurricane Michael spinning in the Atlantic Ocean. Imagery from NASA's Aqua and Terra satellites showed Leslie now past Bermuda and Michael in the north central Atlantic, and Leslie is much larger than the smaller, more powerful Michael. Images of each storm were taken by the Moderate Resolution Imaging Spectroradiometer, or MODIS instrument that flies onboard both the Aqua and Terra satellites. Both satellites captured images of both storms on Sept. 7 and Sept. 10. The image from Sept. 7 showed a much more compact Michael with a visible eye. By Sept. 10, the eye was no longer visible in Michael and the storm appeared more elongated from south to north. To continue reading go to: 1.usa.gov/NkUPqn NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram

  12. Interview with J. Michael Thompson

    ERIC Educational Resources Information Center

    Randall, Mary Elisabeth

    2004-01-01

    J. Michael Thompson is the Vice Provost for Enrollment Management and Dean of Admission and Financial Aid at the University of Southern California. J. Michael has worked in higher education for more than 30 years in a variety of roles at small private and mid-sized and large public universities, and now at USC, a large private university. He has…

  13. Veteran’s Health Care Issues

    DTIC Science & Technology

    2007-11-30

    Affairs Dr. Michael J. Kussman , in U.S. Congress, House Committee on Veterans’ Affairs Subcommittee on Oversight and Investigations, hearing on...Health, Department of Veterans Affairs, Michael Kussman , in U.S. Congress, House Committee on Appropriations, Subcommittee on Military Construction...Department of Veterans Affairs Dr. Michael J. Kussman , in U.S. Congress, House Committee on Veterans’ Affairs Subcommittee on Oversight and

  14. 78 FR 6851 - Proposed Information Collection (Patient Satisfaction Survey Michael E. DeBakey Home Care Program...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-31

    ... (Patient Satisfaction Survey Michael E. DeBakey Home Care Program) Activity: Comment Request AGENCY... Satisfaction Survey Michael E. DeBakey Home Care Program, VA Form 10-0476. OMB Control Number: 2900-0775. Type... gather feedback from patients regarding their satisfaction with the quality of services/care provided by...

  15. Michael Young and the Curriculum Field in South Africa

    ERIC Educational Resources Information Center

    Hoadley, Ursula

    2015-01-01

    The paper addresses the question of what we should make of Michael Young's recent work with respect to curriculum theory by considering the particular case of South African curriculum reform. The paper thus traces two trajectories: the evolution of Michael Young's ideas over time and South African curriculum reform in the post-apartheid period.…

  16. Covalent Modifiers: A Chemical Perspective on the Reactivity of α,β-Unsaturated Carbonyls with Thiols via Hetero-Michael Addition Reactions.

    PubMed

    Jackson, Paul A; Widen, John C; Harki, Daniel A; Brummond, Kay M

    2017-02-09

    Although Michael acceptors display a potent and broad spectrum of bioactivity, they have largely been ignored in drug discovery because of their presumed indiscriminate reactivity. As such, a dearth of information exists relevant to the thiol reactivity of natural products and their analogues possessing this moiety. In the midst of recently approved acrylamide-containing drugs, it is clear that a good understanding of the hetero-Michael addition reaction and the relative reactivities of biological thiols with Michael acceptors under physiological conditions is needed for the design and use of these compounds as biological tools and potential therapeutics. This Perspective provides information that will contribute to this understanding, such as kinetics of thiol addition reactions, bioactivities, as well as steric and electronic factors that influence the electrophilicity and reversibility of Michael acceptors. This Perspective is focused on α,β-unsaturated carbonyls given their preponderance in bioactive natural products.

  17. 77 FR 30047 - Notice of Opportunity for Public Comment on Surplus Property Release at Michael J Smith Field...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-21

    ... Comment on Surplus Property Release at Michael J Smith Field, Beaufort, NC AGENCY: Federal Aviation... J Smith Field, be used for aeronautical purposes. DATES: Comments must be received on or before June... property at the Michael J Smith Field. The property consists of one parcel located on the north side of...

  18. STS-72 Mission Specialist Koichi Wakata during ASCAN training

    NASA Image and Video Library

    1995-01-09

    S95-00353 (12-14 September 1992) --- Several 1992 astronaut candidates brush the sand and gravel off one another following one of several phases of parachute familiarization and survival training at Vance Air Force Base in Oklahoma. Recognizable in the picture are Wendy B. Lawrence, Michael E. Lopez-Alegria, Chris A. Hadfield, Winston E. Scott and Koichi Wakata. The trainees had just completed an exercise, which required their jumping off a box into a gravel pit, in order to familiarize them the proper way to meet the ground following an emergency parachute drop.

  19. Research and Development of Methods for Estimating Physicochemical Properties of Organic Compounds of Environmental Concern. Part 1.

    DTIC Science & Technology

    1981-06-01

    REEHL, D H ROSENBLATT OAMD 17-8-C-8073 UNCLASSIFIED ADL-C-A2426 PT- 1 NL 6 fllfllflfflfl lll mhhhhhhhh IIIIIIIIIIIIII IIIIIIIIIIIIII IIIIIIIIIIIIII...PHASE 11 (PART 1 OF 2 PARTS) by Warren J. Lyman, Ph.D.- Michael J. Hayes James D. Blrkett, Ph.D. Leslie H. Nelken Sara E. Bysshe Carl E. Rechstelner...CONtES PART 1 Executive Summary 2 Acknowedgmnwt 4 Table of Cotnts 7 Ust of Tables 23 List of FIgures 36 Introduction 39 1 - Octanol/Wter Partition

  20. Presentations at CALS Conference (Computer-Aided Acquisition and Logistic Support). Phase 1.2 Conferences. A DoD/Industry/NIST (National Institute of Standards Technology) Conference Held in Philadelphia, PA on 20 Apr 1989, Anaheim, CA on 27 Apr 1989 and Gaithersburg, MD on 2 May 1989

    DTIC Science & Technology

    1989-05-02

    DELIVERIES BEGIN 1990. 29 Air Force Tech Order Management System (AFTOMS) -B. ’C. AT - L Amtiorng TOC /Reglonal DC $can? Y AcquIsition Becomeis Azchlvlng N...Keyport, WA 98345 309-782-5804 Pittsfield, MA 01201 206-396-4200 413-494-5944 Mr. F.A. Paris Mr. Kevin D. Paulson Mr. Michael 0. PetreaGud Sistemas

  1. DefenseLink Feature: Chairman Visits Japan and Republic of Korea, Nov. 5-8,

    Science.gov Websites

    Staff Navy Adm. Michael G. Mullen answers questions at a press availability with local media following Staff Navy Adm. Michael G. Mullen visits greets marines and staff assigned to the U.S. Embassy, Tokyo the Joint Chiefs of Staff U.S. Navy Adm. Michael G. Mullen, right, and Japanese Chief of Defense Adm

  2. Phosphopeptide Enrichment by Covalent Chromatography after Derivatization of Protein Digests Immobilized on Reversed-Phase Supports

    PubMed Central

    Nika, Heinz; Nieves, Edward; Hawke, David H.; Angeletti, Ruth Hogue

    2013-01-01

    A rugged sample-preparation method for comprehensive affinity enrichment of phosphopeptides from protein digests has been developed. The method uses a series of chemical reactions to incorporate efficiently and specifically a thiol-functionalized affinity tag into the analyte by barium hydroxide catalyzed β-elimination with Michael addition using 2-aminoethanethiol as nucleophile and subsequent thiolation of the resulting amino group with sulfosuccinimidyl-2-(biotinamido) ethyl-1,3-dithiopropionate. Gentle oxidation of cysteine residues, followed by acetylation of α- and ε-amino groups before these reactions, ensured selectivity of reversible capture of the modified phosphopeptides by covalent chromatography on activated thiol sepharose. The use of C18 reversed-phase supports as a miniaturized reaction bed facilitated optimization of the individual modification steps for throughput and completeness of derivatization. Reagents were exchanged directly on the supports, eliminating sample transfer between the reaction steps and thus, allowing the immobilized analyte to be carried through the multistep reaction scheme with minimal sample loss. The use of this sample-preparation method for phosphopeptide enrichment was demonstrated with low-level amounts of in-gel-digested protein. As applied to tryptic digests of α-S1- and β-casein, the method enabled the enrichment and detection of the phosphorylated peptides contained in the mixture, including the tetraphosphorylated species of β-casein, which has escaped chemical procedures reported previously. The isolates proved highly suitable for mapping the sites of phosphorylation by collisionally induced dissociation. β-Elimination, with consecutive Michael addition, expanded the use of the solid-phase-based enrichment strategy to phosphothreonyl peptides and to phosphoseryl/phosphothreonyl peptides derived from proline-directed kinase substrates and to their O-sulfono- and O-linked β-N-acetylglucosamine (O-GlcNAc)-modified counterparts. Solid-phase enzymatic dephosphorylation proved to be a viable tool to condition O-GlcNAcylated peptide in mixtures with phosphopeptides for selective affinity purification. Acetylation, as an integral step of the sample-preparation method, precluded reduction in recovery of the thiolation substrate caused by intrapeptide lysine-dehydroalanine cross-link formation. The solid-phase analytical platform provides robustness and simplicity of operation using equipment readily available in most biological laboratories and is expected to accommodate additional chemistries to expand the scope of solid-phase serial derivatization for protein structural characterization. PMID:23997662

  3. Covalent Modifiers: A Chemical Perspective on the Reactivity of α,β-Unsaturated Carbonyls with Thiols via Hetero-Michael Addition Reactions

    PubMed Central

    Jackson, Paul A.; Widen, John C.; Harki, Daniel A.; Brummond, Kay M.

    2017-01-01

    Although Michael acceptors display a potent and broad spectrum of bioactivity, they have largely been ignored in drug discovery because of their presumed indiscriminate reactivity. As such, a dearth of information exists relevant to the thiol reactivity of natural products and their analogs possessing this moiety. In the midst of recently approved acrylamide-containing drugs, it is clear that a good understanding of the hetero-Michael addition reaction and the relative reactivities of biological thiols with Michael acceptors under physiological conditions is needed for the design and use of these compounds as biological tools and potential therapeutics. This perspective provides information that will contribute to this understanding, such as kinetics of thiol addition reactions, bioactivities, as well as steric and electronic factors that influence the electrophilicity and reversibility of Michael acceptors. This perspective is focused on α,β-unsaturated carbonyls given their preponderance in bioactive natural products. PMID:27996267

  4. Strategic Studies Quarterly. Volume 8, Number 3, Fall 2014

    DTIC Science & Technology

    2014-01-01

    Michael Guillot Measuring Military Power James Jay Carafano Strategy and Force Planning in a Time of Austerity BG Michael J . Meese, USA, Retired...Hudson, PhD Nori Katagiri, PhD Paul J . Springer, PhD Zachary J . Zwald, PhD Strategic Studies Quarterly (SSQ) (ISSN 1936-1815) is published quarterly...19 BG Michael J . Meese, USA, Retired Pensive Sword: Educating Officers in Austere Times ...................... 30 Stephen D. Chiabotti Feature

  5. DefenseLink.mil - Pentagon Memorial Dedication

    Science.gov Websites

    Dept. photo by Army Staff Sgt. Michael J. Carden An entry stone at the Pentagon Memorial lists the their lives during the Sept. 11 terrorist attack on the Pentagon. Photo by Staff Sgt. Michael J. Carden Staff Sgt. Michael J. Carden A member of The United States Air Force Band practices before the start of

  6. Hearts-and-Minds: A Strategy of Conciliation, Coercion, or Commitment?

    DTIC Science & Technology

    2012-09-01

    benefits to modern conflicts remains problematic. According to Colonel (retired) Michael Crawshaw writing on evolution of British COIN for the United...Richmond, UK: Curzon Press, 2002), 11. 9. Michael Crawshaw , “The Evolution of British COIN,” Se- curity and Stabilisation: The Military Contribution...Afghanistan” (Cahier de la Recherche, France: November 2011), 42. 12. Ibid., 43. 13. Michael Crawshaw , “The Evolution of British COIN,” Se- curity and

  7. Development and Implementation of an Interactive Uniform Regulations Manual for the United States Marine Corps

    DTIC Science & Technology

    2006-09-01

    IMPLEMENTATION OF AN INTERACTIVE UNIFORM REGULATIONS MANUAL FOR THE UNITED STATES MARINE CORPS by Michael H. Villar Carsten Krause...SUBTITLE: Development and Implementation of an Interactive Uniform Regulations Manual for the United States Marine Corps 6. AUTHOR(S) Michael H. Villar...IMPLEMENTATION OF AN INTERACTIVE UNIFORM REGULATIONS MANUAL FOR THE UNITED STATES MARINE CORPS Michael H. Villar Major, United States Marine Corps B.A

  8. Understanding a Complex World: Why an Emphasis on Empathy Could Better Enable Army Leaders to Win

    DTIC Science & Technology

    2016-06-10

    complexity and speed of human interactions. Through the analysis of case studies involving General Stanley McChrystal and Colonel Michael Steele , this...Future; Win; Dilemma; Leadership; McChrystal, Stanley; Steele , Michael 16. SECURITY CLASSIFICATION OF: 17. LIMITATION OF ABSTRACT 18. NUMBER OF...Stanley McChrystal and Colonel Michael Steele , this thesis describes how each individual’s empathetic mindset resulted in both favorable and

  9. Combat Service Support MOD II Design (CSS MOD II). Volume 2. Appendixes

    DTIC Science & Technology

    1986-10-01

    through contractual aoreement with Michael Jackson , Ltd. London. The spelling, syntax, and word usage adopted throughout the document have been made...to conform to army standards. The design teas members wish to thank the followin, individuals for their assistances Mr. John Cameron, Michael Jackson , Ltd...JSP) methodology is a product of Michael Jackson Systems, Ltd., London, England. In 1984, Dr. Wilbur Payne, Director, TRADOC Operations Research

  10. Psychological Analyses of Courageous Performance in Military Personnel

    DTIC Science & Technology

    1990-08-01

    British Columbia ARI Scientific Coordination Office, London Milton Katz, Chief Office of Basic Research Michael Kaplan , Director OTIC August1990 ELECTE...For NTIS Ri University of British Columbia DTic TAB Just fitIcat lo Technical review by Dy __Dttibut ton/ Michael Kaplan Avallability CodesDIst...22c. OFFICE SYMBOL Michael Kaplan (202) 274-8722 PERT-BR DD Form 1473, JUN 86 Previous editions are obsolete. SECURITY CLASSIFICATION OF THIS PAGE

  11. Development and Implementation of Low-Cost Mobile Sensor Platforms Within a Wireless Sensor Network

    DTIC Science & Technology

    2010-09-01

    WIRELESS SENSOR NETWORK by Michael Jay Tozzi September 2010 Thesis Advisor: Rachel Goshorn Second Reader: Duane Davis Approved for...Platforms Within a Wireless Sensor Network 6. AUTHOR(S) Tozzi, Michael Jay 5. FUNDING NUMBERS 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) Naval...IMPLEMENTATION OF LOW-COST MOBILE SENSOR PLATFORMS WITHIN A WIRELESS SENSOR NETWORK Michael Jay Tozzi Lieutenant, United States Navy B.S., United

  12. Report of the IAU Working Group on Solar Eclipses

    NASA Astrophysics Data System (ADS)

    Pasachoff, Jay M.

    2015-08-01

    The Working Group on Solar Eclipses coordinates scientists and information in the study of the Sun and the heliosphere at solar eclipses. Our Website at http://eclipses.info has a wide variety of information, including links to maps and other websites dealing with solar eclipses, as well as information on how to observe the partial-phases of solar eclipses safely and why it is interesting for not only scientists but also for the public to observe eclipses and to see how we work to uncover the mysteries of the sun's upper atmosphere. In the last triennium, there were total eclipses in Australia and the Pacific in 2012; in an arc across Africa from Gabon to Uganda and Kenya in 2013; and in the Arctic, including Svalbard and the Faeroes plus many airplanes aloft, in 2015. In the coming triennium, there will be total solar eclipses in Indonesia and the Pacific in 2016 and then, on 21 August 2017, a total solar eclipse that will sweep across the Continental United States from northwest to southeast. Mapping websites, all linked to http://eclipses.info, include Fred Espenak's http://EclipseWise.com; Michael Zeiler's http://GreatAmericanEclipse.com and http://eclipse-maps.com; Xavier Jubier's http://xjubier.free.fr; and (with weather and cloudiness analysis) Jay Anderson's http://eclipser.ca. Members of the Working Group, chaired by Jay Pasachoff (U.S.), include Iraida Kim (Russia), Kiroki Kurokawa (Japan), Jagdev Singh (India), Vojtech Rusin (Slovakia), Zhongquan Qu (China), Fred Espenak (U.S.), Jay Anderson (Canada), Glenn Schneider (U.S.), Michael Gill (U.K.), Xavier Jubier (France), Michael Zeiler (U.S.), and Bill Kramer (U.S.).

  13. Unconventional Counterinsurgency: Leveraging Traditional Social Networks and Irregular Forces in Remote and Ungoverned Areas

    DTIC Science & Technology

    2010-05-13

    Identity: Why We Are Losing Our Wars”, Michael Vlahos argues that today’s wars with non-state enemies are “above all, wars of identity.”29 Moreover, he...together these manuals powerfully reinforce Michael Vlahos ’ imperative to reshape the population and enemy narrative by co-opting identity.34...29 Michael Vlahos , "Fighting Identity: Why We Are Losing Our Wars," Military Review (United States

  14. Topological Privacy: Lattice Structures and Information Bubbles for Inference and Obfuscation

    DTIC Science & Technology

    2016-12-19

    AFRL-AFOSR-VA-TR-2017-0036 Topological Privacy Michael Erdmann CARNEGIE MELLON UNIVERSITY 5000 FORBES AVENUE PITTSBURGH, PA 15213-3815 02/22/2017...PERSON 19b. TELEPHONE NUMBER (Include area code) 19-12-2016 Final 15-10-2013 - 14-10-2016 Topological Privacy Erdmann, Michael, A. Carnegie Mellon...Michael Erdmann Carnegie Mellon University me@cs.cmu.edu December 19, 2016 Abstract Information has intrinsic geometric and topological structure, arising

  15. Description and Evaluation of GDEM-V 3.0

    DTIC Science & Technology

    2009-02-06

    Description and Evaluation of GDEM -V 3.0 Michael R. caRnes Ocean Sciences Branch Oceanography Division February 6, 2009 i REPORT DOCUMENTATION PAGE Form...include area code) b. ABSTRACT c. THIS PAGE 18. NUMBER OF PAGES 17. LIMITATION OF ABSTRACT Description and Evaluation of GDEM -V 3.0 Michael R. Carnes...unlimited. Unclassified Unclassified Unclassified UL 24 Michael R. Carnes (228) 688-5648 The GDEM (Generalized Digital Environment Model) has served as

  16. Novel Array-Based Target Identification for Synergistic Sensitization of Breast Cancer to Herceptin

    DTIC Science & Technology

    2010-05-01

    Tatsuya Azum, Eileen Adamson, Ryan Alipio, Becky Pio, Frank Jones, Dan Mercola. Chip- on- chip analysis of mechanism of action of HER2 inhibition in...Munawar, Kutbuddin S. Doctor, Michael Birrer, Michael McClelland, Eileen Adamson, Dan Mercola. Egr1 regulates the coordinated expression of numerous...Kemal Korkmaz, Mashide Ohmichi, Eileen Adamson, Michael McClelland, Dan Mercola. Identification of genes bound and regulated by ATF2/c-Jun

  17. Structuring Z Specifications with Views

    DTIC Science & Technology

    1994-03-01

    Gregory Abowd, Michael Jackson , Jeannette Wing, Michal Young and Pamela Zave, who gave me helpful comments on drafts of this pa- per. I am also grateful to...1988. Uac94] Michael Jackson , "Software Development Method", in A Classical Mind: Essays in Honour of C.A.R Hoare, ed. A.W Roscoe, Prentice Hall...International, 1994. ,0 26 [Jon86] Cliff B. Jones, Systematic Software Development Using VDM, Prentice Hall International, 1986. [JZ93] Michael Jackson and

  18. Test and Evaluation of the Navy Occupational Health Information Management System (NOHIMS).

    DTIC Science & Technology

    1986-07-01

    Naval Shipyard for NOHIMS with the assistance of Todd Merrill from the University of Washington and Michael Jackson , another industrial hygienist...initialize NOHIMS and learn how to use the system. As the industrial component of NOHIMS became operational in Bremerton, Michael Jackson assumed the role...interacting with the system. Since NO|IIMS was introduced at Bremerton, Michael Jackson has been involved in all aspects of system start-up and maintenance

  19. Plant canopy gap-size analysis theory for improving optical measurements of leaf-area index

    NASA Astrophysics Data System (ADS)

    Chen, Jing M.; Cihlar, Josef

    1995-09-01

    Optical instruments currently available for measuring the leaf-area index (LAI) of a plant canopy all utilize only the canopy gap-fraction information. These instruments include the Li-Cor LAI-2000 Plant Canopy Analyzer, Decagon, and Demon. The advantages of utilizing both the canopy gap-fraction and gap-size information are shown. For the purpose of measuring the canopy gap size, a prototype sunfleck-LAI instrument named Tracing Radiation and Architecture of Canopies (TRAC), has been developed and tested in two pure conifer plantations, red pine (Pinus resinosa Ait.) and jack pine (Pinus banksiana Lamb). A new gap-size-analysis theory is presented to quantify the effect of canopy architecture on optical measurements of LAI based on the gap-fraction principle. The theory is an improvement on that of Lang and Xiang [Agric. For. Meteorol. 37, 229 (1986)]. In principle, this theory can be used for any heterogeneous canopies.

  20. Bronze-mean hexagonal quasicrystal

    NASA Astrophysics Data System (ADS)

    Dotera, Tomonari; Bekku, Shinichi; Ziherl, Primož

    2017-10-01

    The most striking feature of conventional quasicrystals is their non-traditional symmetry characterized by icosahedral, dodecagonal, decagonal or octagonal axes. The symmetry and the aperiodicity of these materials stem from an irrational ratio of two or more length scales controlling their structure, the best-known examples being the Penrose and the Ammann-Beenker tiling as two-dimensional models related to the golden and the silver mean, respectively. Surprisingly, no other metallic-mean tilings have been discovered so far. Here we propose a self-similar bronze-mean hexagonal pattern, which may be viewed as a projection of a higher-dimensional periodic lattice with a Koch-like snowflake projection window. We use numerical simulations to demonstrate that a disordered variant of this quasicrystal can be materialized in soft polymeric colloidal particles with a core-shell architecture. Moreover, by varying the geometry of the pattern we generate a continuous sequence of structures, which provide an alternative interpretation of quasicrystalline approximants observed in several metal-silicon alloys.

  1. Growth of two-dimensional decagonal colloidal quasicrystals

    NASA Astrophysics Data System (ADS)

    Martinsons, M.; Schmiedeberg, M.

    2018-06-01

    The growth of quasicrystals, i.e. structures with long-range positional order but no periodic translational symmetry, is more complex than the growth of periodic crystals. By employing Brownian dynamics simulations in two dimensions for colloidal particles that interact according to an isotropic pair potential with two incommensurate lengths, we study the growth of quasicrystalline structures by sequentially depositing particles at their surface. We quantify the occurrence of quasicrystalline order as a function of the temperature and the rate of added particles. In addition, we explore defects like local triangular order or gaps within the quasicrystalline structure. Furthermore, we analyze the shapes of the surfaces in grown structures which tend to build straight lines along the symmetry axes of the quasicrystal. Finally, we identify phasonic flips which are rearrangements of the particles due to additional degrees of freedom. The number of phasonic flips decreases with the distance to the surface.

  2. Searching for a Different Understanding of Operational Art

    DTIC Science & Technology

    2016-05-26

    that “hampered by 35 Bruce Menning, “Operational Art’s Origins,” in Historical Perspectives of the Operational Art, ed. Michael D. Krause and R. Cody...war or theater of 43 Clayton Newell, “Introduction,” in On Operational Art, ed. Clayton Newell and Michael Krause (Washington, DC: US Army Center of...Menning, Bruce. “Operational Art’s Origins.” In Historical Perspectives of the Operational Art, edited by Michael D. Krause and R. Cody Phillips, 3

  3. Preparing Brigade Combat Team Soldiers for Mission Readiness Through Research on Intangible Psychological Constructs and their Applications: Validation and Pilot

    DTIC Science & Technology

    2015-01-01

    and their Applications: Validation and Pilot Steven N. Aude Kenneth Nicely Michael A. Lodato ICF International Christopher L. Vowels...CONTRACT OR GRANT NUMBER W5J9CQ-11-0009 5b. PROGRAM ELEMENT NUMBER 622785 6. AUTHOR(S) Steven N. Aude, Kenneth Nicely, Michael A... Michael A. Lodato ICF International Christopher L. Vowels U.S. Army Research Institute Fort Hood Research Unit Brian T. Crabb

  4. Gas Control and Thermal Modeling Methods for Pressed Pellet and Fast Rise Thin-Film Thermal Batteries

    DTIC Science & Technology

    2015-09-01

    Thin-Film Thermal Batteries by Frank C Krieger and Michael S Ding Approved for public release; distribution unlimited...Laboratory Gas Control and Thermal Modeling Methods for Pressed Pellet and Fast Rise Thin-Film Thermal Batteries by Frank C Krieger and Michael S...Batteries 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Frank C Krieger and Michael S Ding 5d. PROJECT NUMBER

  5. Production of a Novel OX40 Ligand for Clinical Use

    DTIC Science & Technology

    2012-10-01

    inhibitory to the detection of mycoplasma. 19.0 TECHNICAL REFERENCES 19.1 Barile , Michael F. and McGarrity, Gerard J. (1983). "Isolation of Mycoplasmas from...Edition, Section 2.6.7, Mycoplasmas. 19.4 McGarrity, Gerard J. and Barile , Michael F. (1983). "Use of Indicator Cell Lines for Recovery and...test material will be discarded following study completion unless otherwise requested by Sponsor. 20.0 REFERENCES 20.1 Barile , Michael F. and

  6. Magnetic Insulation in Coaxial Transmission Lines with an External Magnetic Field

    DTIC Science & Technology

    1980-03-13

    A. Mostrom, Michael E. Jones, and Lester E. Thode SUBMITTED TO: Physical Review Letters March 13, 1980 SöKOK_Kä^MJ!L;; ÄgEie?©d tea gas &c...Number Assigned by Contract Monitor: SLL 81- 262 Comments on Document: Archive, RRI, DEW . From Physical Review Letters Descriptors, Keywords: Magnetic...Source of Document: DEW MAGNETIC INSULATION IN COAXIAL TRANSMISSION LINES WITH AN EXTERNAL MAGNETIC FIELD Michael A. Mostrom, Michael E. Jones, and

  7. The Russo-Japanese War, Lessons Not Learned

    DTIC Science & Technology

    2003-05-06

    USACGSC, August, 2002), CR3.7-1--CR3.7-14; Michael Howard , “Men Against Fire, Expectations of War in 1914,” International Security (Summer 1984): 41-57...169; Carl von Clausewitz, On War, trans. and ed. Michael Howard and Peter Paret (Princeton: Princeton University Press, 1984), 37-38. 8Service in...Cleator, P. Weapons of War. New York: Thomas Y. Crowell Company, 1967. Clausewitz, Carl von. On War. Edited and translated by Michael Howard and

  8. Evaluating perceptions of the effectiveness of the community advisory panel model for enhancing service delivery to marginalized populations.

    PubMed

    Ramsay, Jason T; Smith, Peter; Thompson, Alison; O'Campo, Patricia; Nisenbaum, Rosane; Watson, Priya; Park-Wylie, Laura; Bryant, Toba; Tandon, Reena; Farah, Mohammed

    2012-01-01

    The objective of this study was to evaluate perceptions of the effectiveness of the community advisory panels (CAPs) at St. Michael's Hospital, in Toronto, Canada. A qualitative design was employed. Participants included hospital staff, patients, Community Advisory Panel chairs, and key informants from community services in the St. Michael's Hospital catchment area. An online survey about awareness of the CAPs and CAP accomplishments; (2) Key informants interviews; and (3) Review of memos and meeting minutes of the CAPs to assess their impact in the hospital and the community. St. Michael's Hospital was the setting of the study. Descriptive statistics were generated for the survey data. Qualitative interview data were coded for major themes. Participants included hospital staff, patients, CAP chairs, and key informants from community services in the St. Michael's Hospital catchment area. Although the CAPs initiated and implemented an array of programs and services at St. Michael's Hospital, the visibility of the CAPs and their service to the hospital and community were very low. Themes that emerged from the semistructured interviews involved the visibility, effectiveness, and role of the CAPs in the hospital. Although the CAPs at St. Michael's Hospital appear to be an effective model for community responsiveness, the visibility of their work in the hospital and community was very low. © 2012 Wiley Periodicals, Inc.

  9. Michael Griffin House Science Committee Hearing

    NASA Image and Video Library

    2005-06-27

    NASA Administrator Michael Griffin prepares to testify at a hearing before the House Science Committee, Tuesday, June 28, 2005, Rayburn House Office building, Washington. Photo Credit: (NASA/Bill Ingalls)

  10. Geophysicists

    NASA Astrophysics Data System (ADS)

    2004-06-01

    In Memoriam: James R. Holton, Buford K. Meade, Mikhail I. Pudovkin; Honors: Michel Blanc, Alberto Borges, Paola Vannucchi, Michael A. Hapgood, Subir Banerjee, Lev Vinnik, John Wahr, Forrest Mozer, Vladimir N. Zharkov, Michael Ghil

  11. Michael Griffin House Science Committee Hearing

    NASA Image and Video Library

    2005-06-27

    Rep. Bart Gordon, D-TN., questions NASA Administrator Michael Griffin during a House Science Committee hearing, Tuesday, June 28, 2005, Rayburn House Office building, Washington. Photo Credit: (NASA/Bill Ingalls)

  12. ASK Talks with Dr. Michael Hecht

    NASA Technical Reports Server (NTRS)

    Hecht, Michael

    2003-01-01

    Michael Hecht has been a member of NASA's Jet Propulsion Laboratory (JPL) staff since 1982. He is currently Project Manager and co-investigator for the Mars Environmental Compatibility Assessment (MECA)

  13. Michael Thackeray on Lithium-air Batteries

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Thackeray, Michael

    2009-01-01

    Michael Thackeray, Distinguished Fellow at Argonne National Laboratory, speaks on the new technology Lithium-air batteries, which could potentially increase energy density by 5-10 times over lithium-ion batteries.

  14. Michael Thackeray on Lithium-air Batteries

    ScienceCinema

    Thackeray, Michael

    2018-02-06

    Michael Thackeray, Distinguished Fellow at Argonne National Laboratory, speaks on the new technology Lithium-air batteries, which could potentially increase energy density by 5-10 times over lithium-ion batteries.

  15. Dr Michaels® product family (also branded as Soratinex®) versus Methylprednisolone aceponate - a comparative study of the effectiveness for the treatment of plaque psoriasis.

    PubMed

    Hercogovấ, J; Fioranelli, M; Gianfaldoni, S; Chokoeva, A A; Tchernev, G; Wollina, U; Tirant, M; Novotny, F; Roccia, M G; Maximov, G K; França, K; Lotti, T

    2016-01-01

    As one of the most common dermatologic chronic-recurrent disease, variable therapeutic options are available today for management of psoriasis. Although topical high potency corticosteroids, alone or in association with salicylic acid or vitamin D analogues, are still considered the best treatment, they do not seem to possess the capability for a long-term control of the disease or prevent recurrences, as their side effects are major contraindications for continuative use. The aim of this study was to investigate whether Dr. Michaels® product family is comparable to methylprednisolone aceponate (MPA) as a viable alternative treatment option for the treatment and management of stable chronic plaque psoriasis. Thirty adults (13 male, 17 female, mean age 40 years) with mild to severe stable chronic plaque psoriasis, were included in the study. Patients were advised to treat the lesions of the two sides of their body (left and right) with two different unknown modalities for 8 weeks; the pack of Dr. Michaels® products on the left side (consisting of a cleansing gel, an ointment and a skin conditioner) and a placebo pack on the right side, consisting of a cleansing gel, methylprednisolone ointment and a placebo conditioner. Assessment was done using the Psoriasis Activity Severity Index (PASI) scores before treatment and after 2, 4, 6 and 8 weeks. The results achieved with the Dr. Michaels® (Soratinex®) product family for the treatment of chronic plaque psoriasis were better than the results achieved with methylprednisolone aceponate (MPA), even though quicker resolution was achieved with the steroid with 45% of patients achieving resolution within 8-10 days in comparison to 5-6 weeks in the Dr. Michaels® (Soratinex®) group. Before therapy, the mean PASI score of the LHS in Dr. Michaels® (Soratinex®) group was 13.8±4.1 SD and 14.2±4.2 SD in the RHS methylprednisolone aceponate (MPA) group. After 8 weeks of treatment 62% of the Dr. Michaels® (Soratinex®) group had achieved resolution whilst in the methylprednisolone aceponate (MPA) group, the figure remained at 45%. The mean PASI score after 8 weeks of treatment was calculated and in the LHS Dr. Michaels® (Soratinex®) group it was 2.8±1.6 SD and 6.8±2.4 SD in the RHS methylprednisolone aceponate group. In the RHS -methylprednisolone aceponate (MPA) group, 22% of patients failed to respond to the treatment in comparison to 6% in the LHS Dr. Michaels® (Soratinex®) group. Based on the results of this study, Dr. Michaels® products are a more effective treatment option, with insignificant side effects, compared to local treatment with methylprednisolone aceponate (MPA).

  16. Grafting-Density Effects, Optoelectrical Properties and Nano-Patterning of Poly(para-Phenylene) Brushes

    DTIC Science & Technology

    2013-01-01

    NAME OF RESPONSIBLE PERSON 19b. TELEPHONE NUMBER S. Michael Kilbey Dawen Li, Jimmy W. Mays , S. Michael Kilbey II, Jihua Chen, Jose Alonzo, Xiang Yu...Dawen Li,d Jimmy W. Mays ,be Bobby G. Sumpteraf and S. Michael Kilbey II*eg Well-defined conjugated polymers in confined geometries are chal- lenging to...relationships of conned thin lms and may serve as a basis to understand polymer micelles, polymer-stabilized colloid particles, or interfaces compatibi

  17. A Parametric Regression of the Cost of Base Realignment Action (COBRA) Model

    DTIC Science & Technology

    1993-09-20

    Douglas D. Hardman , Captain, USAF Michael S. Nelson, Captain, USAF AFIT/GEE/ENS/93S-03 93 P’ 8 143 Approved for public release, distribution unlimited 93... Hardman CLASS: GEE 93S Captain Michael Nelson TITLE: A Parametric Regression of the Cost of Base Realignment Action (COBRA) Model DEFENSE DATE: 20...Science in Engineering and Environmental Management Douglas D. Hardman , B.S.E.E. Michael S. Nelson, B.S.C.E Captain, USAF Captain, USAF September 1993

  18. Deception in Covert Nuclear Weapons Development: A Framework to Identify, Analyze, and Mitigate Future Long-Term Deception Efforts

    DTIC Science & Technology

    2016-03-01

    In March, shortly after the BJP’s electoral victory, senior foreign policy advisor N . N . Jha informed U.S. embassy officials in New Delhi that the...College, 1998. Barker, Brian, Michael Clark, Peter Davis, Mark Fisk, Michael Hedlin, Hans Israelsson, Vitaly Khalturin, et al. "Monitoring Nuclear...Pretoria, South Africa, 1981. Mihalka, Michael, German Strategic Deception in the 1930’s, Santa Monica, Calif.: RAND Corporation, N -1557-NA, 1980

  19. Michael Polanyi: Science as Personal Knowledge and Social Practice.

    PubMed

    Nye, Mary Jo

    2017-03-20

    Tacit knowing: 2016 marked the 125th anniversary of the birth of the physical chemist Michael Polanyi, as well as the 40th of his death. This essay discusses his philosophy of science-in particular, his most significant work in this area, Personal Knowledge-from the perspective of his personal biography, as well as its lasting influence on the social sciences. In the photograph: Michael Polanyi at the Fritz Haber Institute in 1968. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  20. Proceedings, Conference and Training Workshop on Wildlife Hazards to Aircraft Held at Charleston, South Carolina on 22-25 May 1984

    DTIC Science & Technology

    1984-05-25

    Aircraft ~.Aut@i~Michael J . Harrison/Sidney A. Gauthreaux, Jr., -Lilia A. Abron-Robinson .WeUi’N.(TiS 9. Pordoni,mg Ogon.m,t,. Nome and AdOda.0...Michael J . Harrison (AAS-330) 16. A4049ract , /-7hese proceedings were developed to enhance information exchange and improve understanding and control of...Wildlife Hazards to Aircraft S Conference and Training Workshop Edited by: Michael J . Harrison Federal Aviation Administration . Dr. Sidney A

  1. Maniac Talk - Michael Kurylo

    NASA Image and Video Library

    2016-11-16

    Michael Kurylo Maniac Lecture, November 16, 2016 NASA climate scientist Michael Kurylo presented a Maniac lecture entitled, "An Uncharted Journey: How I Became an Atmospheric Scientist Rather than a Cowboy or a Farmer." Mike described the path that took him from post-WW II housing projects to and through a rural Connecticut neighborhood, how he became convinced about the unrealistic nature of some early naive career dreams, and how he eventually arrived at a career in atmospheric science (research and program management, and their interface with international environmental policy).

  2. "Anti-Michael addition" of Grignard reagents to sulfonylacetylenes: synthesis of alkynes.

    PubMed

    Esteban, Francisco; Boughani, Lazhar; García Ruano, José L; Fraile, Alberto; Alemán, José

    2017-05-10

    In this work, the addition of Grignard reagents to arylsulfonylacetylenes, which undergoes an "anti-Michael addition", resulting in their alkynylation under very mild conditions is described. The simplicity of the experimental procedure and the functional group tolerance are the main features of this methodology. This is an important advantage over the use of organolithium at -78 °C that we previously reported. Moreover, the synthesis of diynes and other examples showing functional group tolerance in this anti-Michael reaction is also presented.

  3. International Space Station (ISS)

    NASA Image and Video Library

    2001-07-01

    Astronaut Michael L. Gernhardt, STS-104 mission specialist, participates in one of three STS-104 space walks while holding on to the end effector of the Canadarm on the Space Shuttle Atlantis. Gernhardt was joined on the extravehicular activity (EVA) by astronaut James F. Reilly (out of frame). The major objective of the mission was to install and activate the Joint Airlock, which completed the second phase of construction on the International Space Station (ISS). The airlock accommodates both United States and Russian space suits and was designed and built at the Marshall Space Flight Center by the Boeing Company.

  4. MEANS 2: Microstructure- and Micromechanism-Sensitive Property Models for Advanced Turbine Disk and Blade Systems

    DTIC Science & Technology

    2009-12-31

    f„„„,„ -L...-J..— - —I 1 / f+_—=p / —j \\-\\- 4A 14 4A»4 / 4A C4 M / »4.4C A4, «i »A OWOLC $-ISF s - csr !•» ’ML...Materials Society) Publications. 23. S . Ma, L. Carroll and T.M. Pollock, "Development of y Phase Stacking Faults during High Temperature Creep of Ru...into the design of advanced disk and blade systems 6. AUTHOR( S ) Michael J Mills 5. FUNDING NUMBERS FA9550-05-1-0135 7. PERFORMING ORGANIZATION

  5. 78 FR 4406 - Notice of Commission Staff Attendance

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-22

    ... Carolina Electric & Gas Company For more information, contact Michael Lee, Office of Energy Market Regulation, Federal Energy Regulatory Commission at (202) 502-8658 or Michael.Lee@ferc.gov . Dated: January...

  6. New hits as phase II enzymes inducers from a focused library with heteroatom-heteroatom and Michael-acceptor motives.

    PubMed

    Cabrera, Mauricio; de Ovalle, Stefani; Bollati-Fogolín, Mariela; Nascimento, Fabiana; Corbelini, Patrícia; Janarelli, Fernanda; Kawano, Daniel; Eifler-Lima, Vera Lucia; González, Mercedes; Cerecetto, Hugo

    2015-11-01

    The increased activity of phase-II-detoxification enzymes, such as quinone reductase (QR) and glutation S -transferase (GST), correlates with protection against chemically induced carcinogenesis. Herein we studied 11 different chemotypes, pyrazole, 1,2,4-oxadiazole, 1,2,5-oxadiazole, 1,2,3-thiadiazole, 1,2,4-thiazole, 1,3,4-oxathiazole, thienyl hydrazone, α,β-unsaturated-oxime, α,β-unsaturated- N -oxide, coumarin and α,β-unsaturated-carbonyl, as phase-II enzymes inducers in order to identify new pharmacophores with chemopreventive activity. Fifty-four compounds were analyzed on wild-type mouse-hepatoma Hepa-1c1c7 and on the aryl-hydrocarbon-nuclear-translocator (Arnt)-defective mutant BpRc1 cells. New monofunctional inducers of QR and GST were identified, the 1,2,5-oxadiazol-2-oxide (3) , the 1,2,4-triazine-4-oxides (23) and (32) and the tetrahydropyrimidinones (28) and (49) . It was confirmed that Nrf2 nuclear translocation is the operative molecular mechanism that allows compound (3) to exert protective effects via expression of downstream phase-II enzymes.

  7. New hits as phase II enzymes inducers from a focused library with heteroatom–heteroatom and Michael-acceptor motives

    PubMed Central

    Cabrera, Mauricio; de Ovalle, Stefani; Bollati-Fogolín, Mariela; Nascimento, Fabiana; Corbelini, Patrícia; Janarelli, Fernanda; Kawano, Daniel; Eifler-Lima, Vera Lucia; González, Mercedes; Cerecetto, Hugo

    2015-01-01

    The increased activity of phase-II-detoxification enzymes, such as quinone reductase (QR) and glutation S-transferase (GST), correlates with protection against chemically induced carcinogenesis. Herein we studied 11 different chemotypes, pyrazole, 1,2,4-oxadiazole, 1,2,5-oxadiazole, 1,2,3-thiadiazole, 1,2,4-thiazole, 1,3,4-oxathiazole, thienyl hydrazone, α,β-unsaturated-oxime, α,β-unsaturated-N-oxide, coumarin and α,β-unsaturated-carbonyl, as phase-II enzymes inducers in order to identify new pharmacophores with chemopreventive activity. Fifty-four compounds were analyzed on wild-type mouse-hepatoma Hepa-1c1c7 and on the aryl-hydrocarbon-nuclear-translocator (Arnt)-defective mutant BpRc1 cells. New monofunctional inducers of QR and GST were identified, the 1,2,5-oxadiazol-2-oxide (3), the 1,2,4-triazine-4-oxides (23) and (32) and the tetrahydropyrimidinones (28) and (49). It was confirmed that Nrf2 nuclear translocation is the operative molecular mechanism that allows compound (3) to exert protective effects via expression of downstream phase-II enzymes. PMID:28031894

  8. Goddard Queen Visit

    NASA Image and Video Library

    2007-05-07

    Prince Philip greets astronauts from STS-125 L to R Andrew J Feustel, Michael T Goode, K. Megan McArthur, Michael J. Massimino, Gregory C. Johnson, and Commander Scott D. Altman. Photo Credit: (NASA/Chris Gunn)

  9. 78 FR 36183 - Notice of Commission Staff Attendance

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-17

    ... Electric & Gas Company For More Information Contact: Michael Lee, Office of Energy Market Regulation, Federal Energy Regulatory Commission at (202) 502-8658 or Michael.Lee@ferc.gov . Dated: June 11, 2013...

  10. Verification Study of Buoyancy-Driven Turbulent Nuclear Combustion

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    None

    2010-01-01

    Buoyancy-driven turbulent nuclear combustion determines the rate of nuclear burning during the deflagration phase (i.e., the ordinary nuclear flame phase) of Type 1a supernovae, and hence the amount of nuclear energy released during this phase. It therefore determines the amount the white dwarf star expands prior to initiation of a detonation wave, and so the amount of radioactive nickel and thus the peak luminosity of the explosion. However, this key physical process is not fully understood. To better understand this process, the Flash Center has conducted an extensive series of large-scale 3D simulations of buoyancy-driven turbulent nuclear combustion for threemore » different physical situations. This movie shows the results for some of these simulations. Credits: Science: Ray Bair, Katherine Riley, Argonne National Laboratory; Anshu Dubey, Don Lamb, Dongwook Lee, University of Chicago; Robert Fisher, University of Massachusetts at Dartmouth and Dean Townsley, University of Alabama Visualization: Jonathan Gallagher, University of Chicago; Randy Hudson, John Norris and Michael E. Papka, Argonne National Laboratory/University of Chicago« less

  11. Michael Griffin House Science Committee Hearing

    NASA Image and Video Library

    2005-06-27

    Members of the media photograph NASA Administrator Michael Griffin as he testifies at a hearing before the House Science Committee, Tuesday, June 28, 2005, Rayburn House Office building, Washington. Photo Credit: (NASA/Bill Ingalls)

  12. Michael Lawson | NREL

    Science.gov Websites

    NREL's Ocean Energy team, Dr. Michael Lawson focuses on the areas of wave and water current energy goal of developing an open source design and analysis tool for wave energy conversion (WEC) devices

  13. Transportation

    DTIC Science & Technology

    2006-01-01

    Ports. Logistics Today, Vol.46. Issue 9. 43. Maloni, Michael ., Jackson , Eric. (2005, Spring). North American Container Port Capacity: A...Literature Review. Transportation Journal, Spring 2005. 16-36. Maloni, Michael ., Jackson , Eric. (2005, Summer). North American Container Port Capacity: An

  14. Employment programs and professionals with a disability.

    PubMed

    Donelly, Michelle; Given, Fiona

    2010-01-01

    It is unclear whether or not open (competitive) employment programs are meeting the needs of the growing numbers of people with a disability seeking professional employment. To understand and describe the experience of a newly graduated professional (Michael) who was seeking open employment support and to analyze those experiences in relation to principles of effective open employment support. Michael a recently graduated accountant who also has a physical disability. A review of the literature was undertaken to identify recommended principles and practices for the conduct of effective open employment and career development programs. A case study was used to describe Michael's experiences as he sought professional employment. Michael's experiences were analysed in relation to recommended principles and practice. The analysis confirmed that the concerns Michael experienced about the supported employment program compromised the effectiveness of the support he received. Employment services based on models of independent living, disability service standards and remediation are likely to focus on the 'pathology' or performance 'deficits' of the person with a disability. Successful open employment models are more likely to place pre-eminence on the perspective of the person with a disability and effective practices for securing employment.

  15. Meet EPA Scientist Michael Nye, Ph.D.

    EPA Pesticide Factsheets

    Michael Nye, Ph.D., is a social scientist who studies natural risk, socio-demographic change and sustainable behavior. Prior to joining EPA, he worked for the UK Environment Agency in flood risk management and emergency preparedness

  16. Thin Film Thermoelectric Metal-Organic Framework with High Seebeck Coefficient and Low Thermal Conductivity. Supporting Information

    DTIC Science & Technology

    2015-04-28

    François Léonard, Vitalie Stavila, Michael E. Foster, Catalin D. Spataru, Reese E. Jones, Brian M. Foley, Patrick E. Hopkins, Mark D. Allendorf, A. Alec...Léonard, Vitalie Stavila, Michael E. Foster, Catalin D. Spataru, Reese E. Jones, Brian M. Foley, Patrick E. Hopkins, Mark D. Allendorf, and A. Alec Talin...Kristopher J. Erickson, François Léonard, Vitalie Stavila, Michael E. Foster, Catalin D. Spataru, Reese E. Jones, Brian M. Foley, Patrick E. Hopkins, Mark D

  17. Biennial Guidance Test Symposium (16th) Held in Holloman Air Force Base, New Mexico on October 5-7, 1993. Volume 1

    DTIC Science & Technology

    1993-10-01

    Michael Swamp, Contraves Inc., Pittsburgh PA; Dr. Michael D. Hooser, CIGTF, Holloman AFB NM Hig h Stability Large Centrifuge Test Bed 305 Dr. Louis A...DeMore, Robert Anticole, and Hans Riggenbach, Contraves Inc, Pittsburgh PA; Dr. Michael D. Hooser, CIGTF, Holloman AFB NM vi SESSION V-A: WEAPONS...power spectral density of input are also frozen out, allowing very low loss referred noise) of 10’ HzŖ below 100 Hz. springs. The input coils are

  18. Book review: Black bass diversity: Multidisciplinary science for conservation

    USGS Publications Warehouse

    Jelks, Howard L.

    2016-01-01

    Review info: Black bass diversity: Multidisciplinary science for conservation. Edited by Michael D. Tringali, James M. Long, Timothy W. Birdsong, and Michael S. Allen, 2015. ISBN: 978-1-934874-40-0, 685 pp.

  19. MIDWEST STRUCTURAL SCIENCES CENTER 2011 ANNUAL REPORT

    DTIC Science & Technology

    2011-10-01

    S. MICHAEL SPOTTSWOOD MICHAEL J. SHEPARD , Chief Senior Aerospace Engineer Analytical Mechanics Branch Analytical...49th AIAA/ASME/ASCE/AHS/ASC Structures, Structural Dynamics & Materials Confe- rence, Chicago , IL, Apr. 7-10, 2008. AIAA 2008-2077. Efstathiou C

  20. 76 FR 25378 - Arts and Artifacts Indemnity Panel Advisory; Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-04

    ... Officer, Michael McDonald, 1100 Pennsylvania Avenue, NW., Washington, DC 20506, or call 202/606-8322. Michael P. McDonald, Management Officer, Advisory Committee. [FR Doc. 2011-10789 Filed 5-3-11; 8:45 am...

  1. Michael Akam and the rise of evolutionary developmental biology

    PubMed Central

    Stern, David L.; Dawes-Hoang, Rachel E.

    2010-01-01

    Michael Akam has been awarded the 2007 Kowalevsky medal for his many research accomplishments in the area of evolutionary developmental biology. We highlight three tributaries of Michael’s contribution to evolutionary developmental biology. First, he has made major contributions to our understanding of development of the fruit fly, Drosophila melanogaster. Second, he has maintained a consistent focus on several key problems in evolutionary developmental biology, including the evolving role of Hox genes in arthropods and, more recently, the evolution of segmentation mechanisms. Third, Michael has written a series of influential reviews that have integrated progress in developmental biology into an evolutionary perspective. Michael has also made a large impact on the field through his effective mentorship style, his selfless promotion of younger colleagues, and his leadership of the University Museum of Zoology at Cambridge and the European community of evolutionary developmental biologists. PMID:20209429

  2. Asymmetric synthesis of α-amino acids via homologation of Ni(II) complexes of glycine Schiff bases. Part 3: Michael addition reactions and miscellaneous transformations.

    PubMed

    Aceña, José Luis; Sorochinsky, Alexander E; Soloshonok, Vadim

    2014-09-01

    The major goal of this review is a critical discussion of the literature data on asymmetric synthesis of α-amino acids via Michael addition reactions involving Ni(II)-complexes of amino acids. The material covered is divided into two conceptually different groups dealing with applications of: (a) Ni(II)-complexes of glycine as C-nucleophiles and (b) Ni(II)-complexes of dehydroalanine as Michael acceptors. The first group is significantly larger and consequently subdivided into four chapters based on the source of stereocontrolling element. Thus, a chiral auxiliary can be used as a part of nucleophilic glycine Ni(II) complex, Michael acceptor or both, leading to the conditions of matching vs. mismatching stereochemical preferences. The particular focus of the review is made on the practical aspects of the methodology under discussion and mechanistic considerations.

  3. Na8Au9.8(4)Ga7.2 and Na17Au5.87(2)Ga46.63: The diversity of pseudo 5-fold symmetries in the Na-Au-Ga system

    NASA Astrophysics Data System (ADS)

    Smetana, Volodymyr; Corbett, John D.; Miller, Gordon J.

    2013-11-01

    The Na-rich part (~30% Na) of the Na-Au-Ga system between NaAu2, NaGa4, and Na22Ga39 has been found to contain the ternary phases Na8Au9.8(4)Ga7.2 (I) and Na17Au5.87(2)Ga46.63 (II), according to the results of single crystal X-ray diffraction measurements. I is orthorhombic, Cmcm, a=5.3040(1), b=24.519(5), c=14.573(3) Å, and contains a network of clusters with local 5-fold symmetry along the a-axis. Such clusters are frequent building units in decagonal quasicrystals and their approximants. II is rhombohedral, R3¯m, a=16.325(2), c=35.242(7) Å, and contains building blocks that are structurally identical to the Bergman-type clusters as well as fused icosahedral units known with active metals, triels and late transition elements. II also contains a polycationic network with elements of the clathrate V type structure. Tight-binding electronic structure calculations using linear muffin-tin-orbital (LMTO) methods on idealized models of I and II indicate that both compounds are metallic with evident pseudogaps at the corresponding Fermi levels. The overall Hamilton bond populations are generally dominated by Au-Ga and Au-Au bonds in I and by Ga-Ga bonds in II; moreover, the Na-Au and Na-Ga contributions in I are unexpectedly large, ~20% of the total. A similar involvement of sodium in covalent bonding has also been found in the electron-richer i-Na13Au12Ga15 quasicrystal approximant.

  4. Michael acceptor containing drugs are a novel class of 5-lipoxygenase inhibitor targeting the surface cysteines C416 and C418.

    PubMed

    Maucher, Isabelle V; Rühl, Michael; Kretschmer, Simon B M; Hofmann, Bettina; Kühn, Benjamin; Fettel, Jasmin; Vogel, Anja; Flügel, Karsten T; Manolikakes, Georg; Hellmuth, Nadine; Häfner, Ann-Kathrin; Golghalyani, Vahid; Ball, Ann-Katrin; Piesche, Matthias; Matrone, Carmela; Geisslinger, Gerd; Parnham, Michael J; Karas, Michael; Steinhilber, Dieter; Roos, Jessica; Maier, Thorsten J

    2017-02-01

    Recently, we published that nitro-fatty acids (NFA) are potent electrophilic molecules which inhibit 5-lipoxygenase (5-LO) by interacting catalytically with cysteine residues next to a substrate entry channel. The electrophilicity is derived from an intramolecular Michael acceptor moiety consisting of an electron-withdrawing group in close proximity to a double bond. The potential of the Michael acceptor moiety to interact with functionally relevant cysteines of proteins potentially renders them effective and sustained enzyme activity modulators. We screened a large library of naturally derived and synthetic electrophilic compounds to investigate whether other types of Michael acceptor containing drugs suppress 5-LO enzyme activity. The activity was measured by assessing the effect on the 5-LO product formation of intact human polymorphonuclear leukocytes. We demonstrated that a number of structurally different compounds were suppressive in the activity assays and showed that Michael acceptors of the quinone and nitro-alkene group produced the strongest inhibition of 5-LO product formation. Reactivity with the catalytically relevant cysteines 416 and 418 was confirmed using mutated recombinant 5-LO and mass spectrometric analysis (MALDI-MS). In the present study, we show for the first time that a number of well-recognized naturally occurring or synthetic anti-inflammatory compounds carrying a Michael acceptor, such as thymoquinone (TQ), the paracetamol metabolite NAPQI, the 5-LO inhibitor AA-861, and bardoxolone methyl (also known as RTA 402 or CDDO-methyl ester) are direct covalent 5-LO enzyme inhibitors that target the catalytically relevant cysteines 416 and 418. Copyright © 2016 Elsevier Inc. All rights reserved.

  5. Dr. Michael DeBakey "is a magician of the heart…"

    MedlinePlus

    ... Dr. DeBakey with NLM's David Nash and admiring students from the Michael E. DeBakey High School for ... medical research as the means of discovering improved methods of diagnosis, treatment, prevention, and cure. As far ...

  6. Michael Griffin Oath Of Office

    NASA Image and Video Library

    2005-04-14

    John H. Marburger, Science Adviser to the President and Director of the Office of Science and Technology Policy (OSTP), left, shakes hands with NASA Administrator Michael Griffin following his swearing-in, Thursday, April 14, 2005, in Washington. Photo Credit: (NASA/Renee Bouchard)

  7. Midwest Structural Sciences Center 2010 Annual Report

    DTIC Science & Technology

    2011-06-01

    S. MICHAEL SPOTTSWOOD MICHAEL J. SHEPARD , Chief Senior Aerospace Engineer Analytical Mechanics Branch Analytical Mechanics Branch Structures...Structural Dynamics & Materials Confe- rence, Chicago , IL, Apr. 7-10, 2008. AIAA 2008-2077. Efstathiou C., Carroll J., Sehitoglu H., Lambros J

  8. Specification Technology Guidebook.

    DTIC Science & Technology

    1985-08-01

    1. General Aspects A. Identification JSD - Jackson System Development -. Michael Jackson Systems Limited 17 Conduit Street London, England WIROTD Tel...USER MANAGER ORGANIZATION ə X _ _ _ _ 1-3__ 3-6 X > 6 _ _ D. Primary Source of Document ation Michael Jackson Systems Limited Also see: References

  9. 33 CFR 110.173 - Port of Charleston, SC.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... located 1800 yards, 118° true from St. Michaels Church Spire and has a diameter of 500 yards. Vessels...°30′ true, 1375 yards from St. Michaels Church Spire and has a diameter of 1400 feet. The use of this...

  10. Operational Leadership in Kosovo

    DTIC Science & Technology

    2004-02-09

    ARRC) LGEN Michael Jackson Allied Air Forces North (COMAIRNORTH) GEN John Jumper Allied Naval Forces North (COMNAVNORTH) U.K. Allied Naval Forces South... Michael Jackson reportedly told the US commander (Clark) during one heated exchange. When General Jackson refused, General Clark asked Admiral James

  11. Highly convergent synthesis of chiral bicyclophosphinates by domino hydrophosphinylation/Michael/Michael reaction.

    PubMed

    Fourgeaud, Pierre; Daydé, Bénédicte; Volle, Jean-Noël; Vors, Jean-Pierre; Van der Lee, Arie; Pirat, Jean-Luc; Virieux, David

    2011-10-07

    Diastereoselective domino reactions of iminoalcohols and allenyl H-phosphinates produce chiral phosphorus bicycles in a regio- and stereoselective fashion. A predictive model for diastereoselection is used for these new chiral phosphinic esters. © 2011 American Chemical Society

  12. Michael Tomasello: Award for Distinguished Scientific Contributions.

    PubMed

    2015-11-01

    The APA Awards for Distinguished Scientific Contributions are presented to persons who, in the opinion of the Committee on Scientific Awards, have made distinguished theoretical or empirical contributions to basic research in psychology. One of the 2015 award winners is Michael Tomasello, who received this award for "outstanding empirical and theoretical contributions to understanding what makes the human mind unique. Michael Tomasello's pioneering research on the origins of social cognition has led to revolutionary insights in both developmental psychology and primate cognition." Tomasello's award citation, biography, and a selected bibliography are presented here. (c) 2015 APA, all rights reserved).

  13. Reflections on Gibbs: From Critical Phenomena to the Amistad

    NASA Astrophysics Data System (ADS)

    Kadanoff, Leo P.

    2003-03-01

    J. Willard Gibbs, the younger was the first American theorist. He was one of the inventors of statistical physics. His introduction and development of the concepts of phase space, phase transitions, and thermodynamic surfaces was remarkably correct and elegant. These three concepts form the basis of different but related areas of physics. The connection among these areas has been a subject of deep reflection from Gibbs' time to our own. I shall talk about these connections by using concepts suggested by the work of Michael Berry and explicitly put forward by the philosopher Robert Batterman. This viewpoint relates theory-connection to the applied mathematics concepts of asymptotic analysis and singular perturbations. J. Willard Gibbs, the younger, had all his achievements concentrated in science. His father, also J. Willard Gibbs, also a Professor at Yale, had one great achievement that remains unmatched in our day. I shall describe it.

  14. Reactivity of Biliatresone, a Natural Biliary Toxin, with Glutathione, Histamine, and Amino Acids

    PubMed Central

    Koo, Kyung A.; Waisbourd-Zinman, Orith; Wells, Rebecca G.; Pack, Michael; Porter, John R.

    2016-01-01

    In our previous work, we identified a natural toxin, biliatresone, from Dysphania glomulifera and D. littoralis, endemic plants associated with outbreaks of biliary atresia in Australian neonatal livestock. Biliatresone is a very rare isoflavonoid with an α-methylene ketone between two phenyls, 1,2-diaryl-2-propenone, along with methylenedioxy, dimethoxyl, and hydroxyl functional groups, that causes extrahepatic biliary toxicity in zebrafish. The toxic core of biliatresone is a methylene in the α-position relative to the ketone of 1,2-diaryl-2-propenone that serves as an electrophilic Michael acceptor. The α-methylene of biliatresone spontaneously conjugated with water and methanol (MeOH), respectively, via Michael addition in a reverse phase high-performance liquid chromatography (RP-HPLC) analysis. We here report the reactivity of biliatresone toward glutathione (GSH), several amino acids, and other thiol- or imidazole-containing biomolecules. LC-MS and HPLC analysis of the conjugation reaction showed the reactivity of biliatresone to be in the order histidine > N-acetyl-d-cysteine (D-NAC) = N-acetyl-l-cysteine (L-NAC) > histamine > glutathione ≥ cysteine ≫ glycine > glutamate > phenylalanine, while serine and adenine had no reactivity due to intramolecular hydrogen bonding in the protic solvents. The reactivity of ethyl vinyl ketone (EVK, 1-penten-3-one), an example of a highly reactive α,ß-unsaturated ketone, toward GSH gave a 6.7-fold lower reaction rate constant than that of biliatresone. The reaction rate constant of synthetic 1,2-diaryl-2-propen-1-one (DP), a core structure of the toxic molecule, was 10-fold and 1.5-fold weaker in potency compared to the reaction rate constants of biliatresone and EVK, respectively. These results demostrated that the methylenedioxy, dimethoxyl, and hydroxyl functional groups of biliatresone contribute to the stronger reactivity of the Michael acceptor α-methylene ketone toward nucleophiles compared to that of DP and EVK. PMID:26713899

  15. Reactivity of Biliatresone, a Natural Biliary Toxin, with Glutathione, Histamine, and Amino Acids.

    PubMed

    Koo, Kyung A; Waisbourd-Zinman, Orith; Wells, Rebecca G; Pack, Michael; Porter, John R

    2016-02-15

    In our previous work, we identified a natural toxin, biliatresone, from Dysphania glomulifera and D. littoralis, endemic plants associated with outbreaks of biliary atresia in Australian neonatal livestock. Biliatresone is a very rare isoflavonoid with an α-methylene ketone between two phenyls, 1,2-diaryl-2-propenone, along with methylenedioxy, dimethoxyl, and hydroxyl functional groups, that causes extrahepatic biliary toxicity in zebrafish. The toxic core of biliatresone is a methylene in the α-position relative to the ketone of 1,2-diaryl-2-propenone that serves as an electrophilic Michael acceptor. The α-methylene of biliatresone spontaneously conjugated with water and methanol (MeOH), respectively, via Michael addition in a reverse phase high-performance liquid chromatography (RP-HPLC) analysis. We here report the reactivity of biliatresone toward glutathione (GSH), several amino acids, and other thiol- or imidazole-containing biomolecules. LC-MS and HPLC analysis of the conjugation reaction showed the reactivity of biliatresone to be in the order histidine > N-acetyl-d-cysteine (D-NAC) = N-acetyl-l-cysteine (L-NAC) > histamine > glutathione ≥ cysteine ≫ glycine > glutamate > phenylalanine, while serine and adenine had no reactivity due to intramolecular hydrogen bonding in the protic solvents. The reactivity of ethyl vinyl ketone (EVK, 1-penten-3-one), an example of a highly reactive α,ß-unsaturated ketone, toward GSH gave a 6.7-fold lower reaction rate constant than that of biliatresone. The reaction rate constant of synthetic 1,2-diaryl-2-propen-1-one (DP), a core structure of the toxic molecule, was 10-fold and 1.5-fold weaker in potency compared to the reaction rate constants of biliatresone and EVK, respectively. These results demostrated that the methylenedioxy, dimethoxyl, and hydroxyl functional groups of biliatresone contribute to the stronger reactivity of the Michael acceptor α-methylene ketone toward nucleophiles compared to that of DP and EVK.

  16. 77 FR 20820 - Change in Bank Control Notices; Acquisitions of Shares of a Bank or Bank Holding Company

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-06

    ... Trust, and Gloria Foley, all of Lovington, Illinois, and Paul Michael Hrvol, Jr. and Paul Michael Hrvol... Bancorp, Inc. and thereby indirectly control Hardware State Bank, both of Lovington, Illinois. Board of...

  17. 76 FR 59416 - Senior Executive Service Performance Review Board

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-26

    ... Anderson, Gary Anderson, Penny Andrews, John Armstrong, Charles R. Armstrong, Sue Athmann, Ronald Ayala, Janice Barber, Delores Baroukh, Nader Bartoldus, Charles Bathurst, Donald Bauhs, Kim Beagles, James... Butcher, Michael Button, Christopher Byrne, Michael Byrne, Sean J. Cahill, Donna L. Callahan, Mary Ellen...

  18. MICHAEL "RUDI" RUDOLPHI SPEAKING AT MISSION SUCCESS FORUM

    NASA Image and Video Library

    2016-06-16

    MICHAEL "RUDI" RUDOLPHI GESTURES DURING A "MISSION SUCCESS IS IN OUR HANDS" SHARED EXPERIENCES FORUM JUNE 16, WHERE HE SPOKE ABOUT HIS "UNFORGETTABLE" EXPERIENCES AS A SENIOR NASA REPRESENTATIVE OVERSEEING DEBRIS RECOVERY EFFORTS FOLLOWING THE LOSS OF SPACE SHUTTLE COLUMBIA AND ITS CREW.

  19. Michael Griffin Meets with Elon Musk

    NASA Image and Video Library

    2005-04-19

    NASA Administrator Michael Griffin, left, meets with CEO of SpaceX Elon Musk, right, Wednesday, April 20, 2005 at NASA Headquarters in Washington. Looking on in the background are Larry Williams, NASA astronaut Marsha Ivins and NASA manager Christopher Shank. Photo Credit: (NASA/Renee Bouchard)

  20. A Perspective on Research Challenges in Information Security

    DTIC Science & Technology

    2011-11-01

    UNCLASSIFIED A Perspective on Research Challenges in Information Security Tamas Abraham, David Adie, Angela Billard, Paul Buckland, Michael Frangos ...Abstract (U) 4. AUTHORS Tamas Abraham, David Adie, Angela Billard, Paul Buckland, Michael Frangos , Ben Long, Mar- tin Lucas, Paul Montague, Dean Philp

  1. Astronaut Michael Clifford takes a break during bailout training

    NASA Technical Reports Server (NTRS)

    1993-01-01

    Astronaut Michael R.U. (Rich) Clifford takes a break while video taping crew mates in training in the JSC Weightless Environment Training Facility (WETF). He is pictured with Trent G. Keeple, a member of the training staff assigned to STS-59.

  2. The Northern Ireland Framework for Peace: Terrorism and its Aftermath

    DTIC Science & Technology

    2012-04-10

    Manchester University Press, 2000. Crawshaw , Colonel (Retd) Michael. The Evolution of British COIN. Joint Doctrine Publication 3-40: 19...Margaret E. McGuinness (Maryland: Rowman & Littlefield, 2000), 206. 35 Colonel (Retd) Michael Crawshaw , “The Evolution of British COIN”. Joint

  3. Meet EPA Ecologist Michael Murrell, Ph.D.

    EPA Pesticide Factsheets

    Michael Murrel, Ph.D., is a EPA research ecologist working on the Gulf of Mexico Hypoxia Project, helping develop models of the northern Gulf to quantify the links between freshwater flowing into the Gulf from the land, nutrients, and hypoxia—“dead zones”

  4. Medical Command in the Contingency Force

    DTIC Science & Technology

    1992-04-15

    briefing. 36. Foust, interview. 37. Interviews with Michael J. Kussman , Carlisle, PA, 10 December 1991 and 5 February 1992. 38. Timboe, interview. 39... Kussman , Michael J., Internal Medicine Consultant to the Army Surgeon General, Office of Medical Corps Affairs, 1989-91. Interviews by author, 10

  5. 77 FR 62490 - Performance Review Board Appointments

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-15

    ...; Gutter, Karis T.; Harden, Krysta.; Hipp, Janie; Holtzman, Max T.; Jett, Carole E.; Jones, Carmen....; Chasteen, G. Taylor; Christian, Lisa A.; Clanton, Michael W.; Coffee, Richard; Farington, Kim S.; Foster....; Watts, Michael; White, John S.; White, Sharmian L.; Wilburn, Curtis; Wilusz, Lisa; Young, Benjamin...

  6. STS-34 Pilot Michael J. McCulley uses ARRIFLEX camera equipment

    NASA Image and Video Library

    1989-04-13

    STS-34 Atlantis, Orbiter Vehicle (OV) 104, Pilot Michael J. McCulley squints while looking through ARRIFLEX camera eye piece during camera briefing at JSC. McCulley rests part of the camera on his shoulder as he operates it.

  7. Michael Sadler and the German Connection.

    ERIC Educational Resources Information Center

    Higginson, J. H.

    1990-01-01

    Chronicles works of Michael Sadler who compared British and German educational systems, emphasizing Germany's contributions in technical education. Presents Sadler's 1912 recommendations--eight lessons premised upon powerful centralized government's ability to implement policy. Reflects on how World War I and Nazism influenced Sadler's thought and…

  8. Michael F. Vaccaro Honors Attorney Fellowship Program in our Philadelphia (Region 3) Office

    EPA Pesticide Factsheets

    The Michael F. Vaccaro Honors Attorney Fellowship provides a unique opportunity to practice law in a major governmental environmental organization, and to receive extensive training in and exposure to environmental law and policy work in the public sector.

  9. Enantioselective Michael Addition of Pyrroles with Nitroalkenes in Aqueous Media Catalyzed by a Water-soluble Catalyst.

    PubMed

    Gui, Yang; Li, Yanan; Sun, Jianan; Zha, Zhenggen; Wang, Zhiyong

    2018-06-11

    A new water-soluble catalytic system were developed and therefor used in an enantioselective Michael addition of pyrroles with nitroalkenes in water to afford the nitroethylpyrrole derivatives with both excellent yields and ee values.

  10. Michael Griffin Senate Hearing

    NASA Image and Video Library

    2005-05-17

    NASA Administrator Dr. Michael Griffin speaks in front of the Senate Commerce Committee Science and Space Subcommittee hearing on Human Space Flight: The Space Shuttle and Beyond, Wednesday, May 18, 2005, in the Russell Senate Office Building on Capitol Hill in Washington. Photo Credit: (NASA/Bill Ingalls)

  11. After This Nothing Happened

    ERIC Educational Resources Information Center

    Alsop, Steve; Fawcett, Leesa

    2010-01-01

    In response to Michiel van Eijck and Wolff-Michael Roth's article and Michael Mueller and Deborah Tippin's rejoinder, we explore traditional ecological knowledges as science education. Adopting a stance of situated partial perspectives, and drawing on selected literature in science and technology studies and feminist postcolonial theories, we…

  12. Theory and practice in action: the contributions of Michael Perkins to clinical linguistics.

    PubMed

    Damico, Jack S; Lynch, Karen E

    2013-01-01

    This article reviews the scholarly contributions of Michael R. Perkins in the discipline of clinical linguistics and provides some indication of the reasons that he has been so successful. Three primary attributes were described through an analysis of his publications.

  13. Operational Art in Cyber Defense

    DTIC Science & Technology

    2013-04-16

    a personal curiosity. I used the masculine when referring to the Commander and the adversary throughout this paper for brevity. Alanis 1...issue 63, (4th quarter 2011): 70-73. 13 Carl von Clausewitz, On War, ed. Michael Howard and Peter Paret, trans . Michael Howard and Peter Paret

  14. Michael Faraday on the Learning of Science and Attitudes of Mind.

    ERIC Educational Resources Information Center

    Crawford, Elspeth

    1998-01-01

    Makes use of Michael Faraday's ideas on learning, focusing on his attitudes toward the unknowns of science and the development of an attitude that improves scientific decision making. This approach acknowledges that there is an inner struggle involved in facing unknowns. (DDR)

  15. A Direct-Learning Approach to Acquiring a Bimanual Tapping Skill.

    PubMed

    Michaels, Claire F; Gomes, Thábata V B; Benda, Rodolfo N

    2017-01-01

    The theory of direct learning (D. M. Jacobs & C. F. Michaels, 2007 ) has proven useful in understanding improvement in perception and exploratory action. Here the authors assess its usefulness for understanding the learning of a motor skill, bimanual tapping at a difficult phase relation. Twenty participants attempted to learn to tap with 2 index fingers at 2 Hz with a phase lag of 90° (i.e., with a right-right period of 500 ms and a right-left period of 125 ms). There were 30 trials, each with 50 tapping cycles. Computer-screen feedback informed of errors in both period and phase for each pair of taps. Participants differed dramatically in their success. Learning was assessed by identifying the succession of attractors capturing tapping over the experiment. A few participants' attractors migrated from antiphase to 90° with an appropriate period; others became attracted to a fixed right-left interval, rather than phase, with or without attraction to period. Changes in attractor loci were explained with mixed success by direct learning, inviting elaboration of the theory. The transition to interval attractors was understood as a change in intention, and was remarkable for its indifference to typical bimanual interactions.

  16. A facile and efficient method of enzyme immobilization on silica particles via Michael acceptor film coatings: immobilized catalase in a plug flow reactor.

    PubMed

    Bayramoglu, Gulay; Arica, M Yakup; Genc, Aysenur; Ozalp, V Cengiz; Ince, Ahmet; Bicak, Niyazi

    2016-06-01

    A novel method was developed for facile immobilization of enzymes on silica surfaces. Herein, we describe a single-step strategy for generating of reactive double bonds capable of Michael addition on the surfaces of silica particles. This method was based on reactive thin film generation on the surfaces by heating of impregnated self-curable polymer, alpha-morpholine substituted poly(vinyl methyl ketone) p(VMK). The generated double bonds were demonstrated to be an efficient way for rapid incorporation of enzymes via Michael addition. Catalase was used as model enzyme in order to test the effect of immobilization methodology by the reactive film surface through Michael addition reaction. Finally, a plug flow type immobilized enzyme reactor was employed to estimate decomposition rate of hydrogen peroxide. The highly stable enzyme reactor could operate continuously for 120 h at 30 °C with only a loss of about 36 % of its initial activity.

  17. KENNEDY SPACE CENTER, FLA. -- From left, NASA Deputy Program Manager of the Space Shuttle Program Michael Wetmore, United Space Alliance (USA) Vice President and Space Shuttle Program Manager Howard DeCastro, NASA Deputy Associate Administrator for Space Station and Shuttle Programs Michael Kostelnik, and a USA technician examine cold plates in Orbiter Processing Facility Bay 2. NASA and USA Space Shuttle program management are participating in a leadership workday. The day is intended to provide management with an in-depth, hands-on look at Shuttle processing activities at KSC.

    NASA Image and Video Library

    2003-12-19

    KENNEDY SPACE CENTER, FLA. -- From left, NASA Deputy Program Manager of the Space Shuttle Program Michael Wetmore, United Space Alliance (USA) Vice President and Space Shuttle Program Manager Howard DeCastro, NASA Deputy Associate Administrator for Space Station and Shuttle Programs Michael Kostelnik, and a USA technician examine cold plates in Orbiter Processing Facility Bay 2. NASA and USA Space Shuttle program management are participating in a leadership workday. The day is intended to provide management with an in-depth, hands-on look at Shuttle processing activities at KSC.

  18. Invited Commentary: Continuing to Loosen the Constraints on Epidemiology in an Age of Change-A Comment on McMichael's "Prisoners of the Proximate".

    PubMed

    Galea, Sandro

    2017-06-01

    Published in 1999, McMichael's "Prisoners of the Proximate: Loosening the Constraints on Epidemiology in an Age of Change" (Am J Epidemiol. 1999;149(10):887-897) outlined an exciting vision for epidemiology as the field that that can help us better understand the drivers of population health so that we may intervene, paving the way for healthier populations. McMichael's paper remains today what it was when it was first published: clear, thoughtful, provocative, and usefully prescriptive in its call to action. McMichael identified 4 constraints facing epidemiology. The field has risen to this challenge and addressed some of these constraints. I discuss how successful (or not) we have been in addressing each of these 4 challenges. © The Author 2017. Published by Oxford University Press on behalf of the Johns Hopkins Bloomberg School of Public Health. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  19. Laboratory experiments of heat and moisture fluxes through supraglacial debris

    NASA Astrophysics Data System (ADS)

    Nicholson, Lindsey; Mayer, Christoph; Wirbel, Anna

    2014-05-01

    Inspired by earlier work (Reznichenko et al., 2010), we have carried out experiments within a climate chamber to explore the best ways to measure the heat and moisture fluxes through supraglacial debris. Sample ice blocks were prepared with debris cover of varying lithology, grain size and thickness and were instrumented with a combination of Gemini TinyTag temperature/relative humidity sensors and Decagon soil moisture sensors in order to monitor the heat and moisture fluxes through the overlying debris material when the experiment is exposed to specified solar lamp radiation and laminar airflow within the temperature-controlled climate chamber. Experimental results can be used to determine the optimal set up for numerical models of heat and moisture flux through supraglacial debris and also indicate the performance limitations of such sensors that can be expected in field installations. Reznichenko, N., Davies, T., Shulmeister, J. and McSaveney, M. (2010) Effects of debris on ice-surface melting rates: an experimental study. Journal of Glaciology, Volume 56, Number 197, 384-394.

  20. Shock Compression Response of Calcium Fluoride (CaF2)

    NASA Astrophysics Data System (ADS)

    Root, Seth

    2017-06-01

    The fluorite crystal structure is a textbook lattice that is observed for many systems, such as CaF2, Mg2 Si, and CeO2. Specifically, CaF2 is a useful material for studying the fluorite system because it is readily available as a single crystal. Under static compression, CaF2 is known to have at least three solid phases: fluorite, cotunnite, and a Ni2 In phase. Along the Hugoniot CaF2 undergoes a fluorite to cotunnite phase transition, however, at higher shock pressures it is unknown whether CaF2 undergoes another solid phase transition or melts directly from the cotunnite phase. In this work, we conducted planar shock compression experiments on CaF2 using Sandia's Z-machine and a two-stage light gun up to 900 GPa. In addition, we use density functional theory (DFT) based quantum molecular dynamics (QMD) simulations to provide insight into the CaF2 state along the Hugoniot. In collaboration with: Michael Desjarlais, Ray Lemke, Patricia Kalita, Scott Alexander, Sandia National Laboratories. Sandia National Laboratories is a multi-mission laboratory managed and operated by Sandia Corporation, a wholly owned subsidiary of Lockheed Martin Corporation, for the U.S. Department of Energy's National Nuclear Security Administration under contract DE-AC04-94AL850.

  1. Asymmetric Michael Addition Mediated by Chiral Ionic Liquids.

    PubMed

    Suzuki, Yumiko

    2018-06-01

    Chiral ionic liquids with a focus on their applications in asymmetric Michael additions and related reactions were reviewed. The examples were classified on the basis of the mode of asymmetric induction (e.g., external induction/non-covalent interaction or internal induction/covalent bond formation), the roles in reactions (as a solvent or catalyst), and their structural features (e.g., imidazolium-based chiral cations, other chiral oniums; proline derivatives). Most of the reactions with high chiral induction are Michael addition of ketones or aldehydes to chalcones or nitrostyrenes where proline-derived chiral ionic liquids catalyze the reaction through enamine/ iminium formation. Many reports demonstrate the recyclability of ionic liquid-tagged pyrrolidines.

  2. Thirty Points About Motivation From Skinner's Book Verbal Behavior

    PubMed Central

    Sundberg, Mark L.

    2013-01-01

    Skinner discussed the topic of motivation in every chapter of the book Verbal Behavior (1957), usually with his preferred terminology of “deprivation, satiation, and aversive stimulation.” In the current paper, direct quotations are used to systematically take the reader through 30 separate points made by Skinner in Verbal Behavior that collectively provide a comprehensive analysis of his position regarding the role of motivation in behavior analysis. In addition, various refinements and extensions of Skinner's analysis by Jack Michael and colleagues (Laraway, Snycerski, Michael, & Poling, 2003; Michael, 1982, 1988, 1993, 2000, 2004, 2007) are incorporated, along with suggestions for research and applications for several of the points. PMID:23814363

  3. Passings to note: Paul Michael Packman, MD; S. Charles Schulz, MD.

    PubMed

    Black, Donald W

    2018-02-01

    One of the keys to the success of Annals of Clinical Psychiatry has always been the tireless efforts of our dedicated Editorial Board. We recently lost 2 longtime Editorial Board members, Drs. Paul Michael Packman and S. Charles Schulz. Both will be greatly missed.

  4. Reading Michael Apple--The Sociological Imagination at Work

    ERIC Educational Resources Information Center

    Ball, Stephen J.

    2007-01-01

    This article discusses Michael Apple's contribution to the sociology of education and education policy analysis and the politics of education. It focuses on ways of "reading" Apple as an intellectual and an activist and looks at the trajectory of his work over a long and illustrious career.

  5. David Cozad, Michael Schumacher and/or Brad Peterson (d/b/a Credit Island Recycling), Davenport, Iowa

    EPA Pesticide Factsheets

    The EPA is providing notice of proposed Administrative Penalty Assessment against David Cozad, Michael Schumacher and/or Brad Peterson (d/b/a Credit Island Recycling), for alleged violations of an industrial stormwater permit issued by IDNR for an applianc

  6. The Holocaust and Education: An Interview with Michael Berenbaum.

    ERIC Educational Resources Information Center

    Goldberg, Mark

    1997-01-01

    In January 1997, Michael Berenbaum became president and chief executive officer of Survivors of the Shoah Visual History Foundation, the organization established by filmmaker Steven Spielberg after completing "Schindler's List." Since 1994, the foundation has been recording eyewitness testimony on the Holocaust. Berenbaum's mandate is to…

  7. Decisionmaker Forums

    DTIC Science & Technology

    2005-03-01

    Committee professional staff, Brian Hurley of Edward Martin & Associates, Michael Kussman of the VA, Steve Lillie of DoD, Steve Mirick ofAMSUSBob...Michael Kussman of VHA; Bruce Levine of VHA; Miklos Losonczy of VHA; Susan Mather of VHA; Theodore Nam of DoD; Harold Wain of DoD; Terry Washam of

  8. HEADSTONES OF BERNARD AND MICHAEL JODD, FATHERANDSON CIVILIANS RESPONSIBLE FOR ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    HEADSTONES OF BERNARD AND MICHAEL JODD, FATHER-AND-SON CIVILIANS RESPONSIBLE FOR CONSTRUCTION OF BRICK PERIMETER WALL WHO DIED OF YELLOW FEVER DURING WALL CONSTRUCTION. VIEW TO WEST. - Baton Rouge National Cemetery, 220 North 19th Street, Baton Rouge, East Baton Rouge Parish, LA

  9. Michael Beitz: Objects of Communication

    ERIC Educational Resources Information Center

    Hoefferle, Mary

    2014-01-01

    For this Instructional Resource, the author interviewed contemporary sculptor Michael Beitz, who uses art to explore the role of designed objects in human communication and emotional experience. This column was written in response to calls for using Enduring Understandings/Big Ideas (National Coalition for Core Arts Standards, 2013; Stewart &…

  10. File System Virtual Appliances: Portable File System Implementations

    DTIC Science & Technology

    2009-05-01

    Mobile Computing Systems and Applications, Santa Cruz, CA, 1994. IEEE. [10] Michael Eisler , Peter Corbett, Michael Kazar, Daniel S. Nydick, and...Gingell, Joseph P. Moran, and William A. Shannon. Virtual Memory Architec- ture in SunOS. In USENIX Summer Conference, pages 81–94, Berkeley, CA, 1987

  11. INCORPORATION OF MECHANISTIC INFORMATION IN THE ARSENIC PBPK MODEL DEVELOPMENT PROCESS

    EPA Science Inventory

    INCORPORATING MECHANISTIC INSIGHTS IN A PBPK MODEL FOR ARSENIC

    Elaina M. Kenyon, Michael F. Hughes, Marina V. Evans, David J. Thomas, U.S. EPA; Miroslav Styblo, University of North Carolina; Michael Easterling, Analytical Sciences, Inc.

    A physiologically based phar...

  12. Introduction to Software Design

    DTIC Science & Technology

    1989-01-01

    Schedules 20 major contributions. We also acknowledge the helpful Worked Examples 20 comments of Larry Peters, Michael Jackson . and Bob Glass. Exercises 20...contrasted with the related For a more general approach to the use of JSP, see work of Warnner and Michael Jackson (JSP). The [Cameron83]. [Ingovaldsson86

  13. Michael Griffin Senate Hearing

    NASA Image and Video Library

    2005-05-17

    NASA Administrator Dr. Michael Griffin is seen during his appearance in front of the Senate Commerce Committee Science and Space Subcommittee hearing on Human Space Flight: The Space Shuttle and Beyond, Wednesday, May 18, 2005, in the Russell Senate Office Building on Capitol Hill in Washington. Photo Credit: (NASA/Bill Ingalls)

  14. Michael Griffin Senate Hearing

    NASA Image and Video Library

    2005-05-17

    NASA Administrator Dr. Michael Griffin smiles during his appearance in front of the Senate Commerce Committee Science and Space Subcommittee hearing on Human Space Flight: The Space Shuttle and Beyond, Wednesday, May 18, 2005, in the Russell Senate Office Building on Capitol Hill in Washington. Photo Credit: (NASA/Bill Ingalls)

  15. Michael Griffin Senate Hearing

    NASA Image and Video Library

    2005-05-17

    NASA Administrator Dr. Michael Griffin delivers a statement during testimony in front of the Senate Commerce Committee Science and Space Subcommittee hearing on Human Space Flight: The Space Shuttle and Beyond, Wednesday, May 18, 2005, in the Russell Senate Office Building on Capitol Hill in Washington. Photo Credit: (NASA/Bill Ingalls)

  16. The power of virtual integration: an interview with Dell Computer's Michael Dell. Interview by Joan Magretta.

    PubMed

    Dell, M

    1998-01-01

    Michael Dell started his computer company in 1984 with a simple business insight. He could bypass the dealer channel through which personal computers were then being sold and sell directly to customers, building products to order. Dell's direct model eliminated the dealer's markup and the risks associated with carrying large inventories of finished goods. In this interview, Michael Dell provides a detailed description of how his company is pushing that business model one step further, toward what he calls virtual integration. Dell is using technology and information to blur the traditional boundaries in the value chain between suppliers, manufacturers, and customers. The individual pieces of Dell's strategy--customer focus, supplier partnerships, mass customization, just-in-time manufacturing--may be all be familiar. But Michael Dell's business insight into how to combine them is highly innovative. Direct relationships with customers create valuable information, which in turn allows the company to coordinate its entire value chain back through manufacturing to product design. Dell describes how his company has come to achieve this tight coordination without the "drag effect" of ownership. Dell reaps the advantages of being vertically integrated without incurring the costs, all the while achieving the focus, agility, and speed of a virtual organization. As envisioned by Michael Dell, virtual integration may well become a new organizational model for the information age.

  17. High Pressure Raman Spectroscopic Studies on CuInTe2 Quantum Dots

    NASA Astrophysics Data System (ADS)

    Yanxon, Howard; Kumar, Ravhi; HiPSEC-University of Nevada Las Vegas Team

    High pressure Raman spectroscopy studies were performed on CuInTe2 Quantum Dots (QD) up to 7.7 GPa. At ambient conditions, the Raman modes of the QD loaded into a high-pressure diamond anvil cell (DAC) were observed at 125.1 cm-1 (A1 mode) and 142.8 cm-1 (B2 or E mode). As the pressure increases, the A1 mode starts to split above 2 GPa and shifts to the left as indication of a structural change. A pressure-induced phase transition was observed around 2.9 GPa due to the collapse of the modes with the appearance of a new Raman peaks. The phase transition observed in our experiments compare well with the characteristics of bulk and larger nanoparticles. Further, it could be concluded that the phase transition pressure observed mainly depends on the particle size. H.Y. thanks McNair foundation for fellowship award. He also acknowledges Melanie White, Jason Baker and Phuc Tran for help in the experiments. He thanks Michael Pravica for using the Raman facility.

  18. The Age of Irregular Warfare: So What?

    DTIC Science & Technology

    2010-01-01

    Lynne Rienner, 2002), and Michael Vlahos , Fighting Identity: Sacred War and World Change (Westport, CT: Praeger Security Interna- tional, 2009). 7...the forms that warfare will take.” 8 I agree with Michael Vlahos that we poten- tially make matters worse by using the image of a triangle to depict

  19. Michael E. Barnes: Award for Distinguished Professional Contributions to Institutional Practice

    ERIC Educational Resources Information Center

    American Psychologist, 2012

    2012-01-01

    Presents a short biography on the winner of the American Psychological Association's Award for Distinguished Professional Contributions to Institutional Practice. The 2012 winner is Michael E. Barnes for his pioneering leadership, dedication, and distinguished contributions to juvenile justice. As chief psychologist of the Superior Court of the…

  20. Catalyst-free and solvent-free Michael addition of 1,3-dicarbonyl compounds to nitroalkenes by a grinding method

    PubMed Central

    Xie, Zong-Bo; Wu, Ming-Yu; He, Ting; Le, Zhang-Gao

    2012-01-01

    Summary An environmentally benign, fast and convenient protocol has been developed for the Michael addition of 1,3-dicarbonyl compounds to β-nitroalkenes in good to excellent yields by a grinding method under catalyst- and solvent-free conditions. PMID:22563352

  1. Solving the Housing Equation: Michael P. Johnson

    ERIC Educational Resources Information Center

    Roach, Ronald

    2005-01-01

    Dr. Michael P. Johnson, an associate professor of management science and urban affairs at the H. John Heinz III School of Public Policy and Management at Carnegie Mellon University in Pittsburgh, is taking management science tools and innovative information technology applications to the housing field. Concerned that organizations that develop and…

  2. Humanism in Education

    ERIC Educational Resources Information Center

    Armstrong, Michael

    2015-01-01

    This is the text of Michael Armstrong's address to the Brian Simon Centenary conference, held at the Institute of Education on 26 March 2015. Michael Armstrong celebrates the humanism that underlay Brian's belief in a common system of education, democratic and non-selective, and finds its counterpart in the creative practice of school children.

  3. Michael Slote and "Sentimentalist Moral Education"

    ERIC Educational Resources Information Center

    Wren, Thomas

    2010-01-01

    Although I think most of what Michael Slote asserts in his article "Sentimentalist moral education" is correct, I worry about three important ideas that are conspicuous by their absence. The first is the possibility that human emotions and feelings are inherently cognitive, which is never considered in his psychological account of empathy. The…

  4. Legitimacy and Penetration in Stability Operations; Setting the Conditions for Perpetual Failure

    DTIC Science & Technology

    2011-12-02

    District or Provincial level. Taking the lessons from Vietnam and 124 Michael Crawshaw , Running a Country: The British Colonial Experience and its Relevance...Metrics of the Afghan War. CSIS presentation, Washington DC: Center for Strategic and International Studies, 2010. Crawshaw , Michael. Running a Country

  5. New Models at Lasell: Q&A with President Michael Alexander

    ERIC Educational Resources Information Center

    Harney, John O.

    2018-01-01

    The "New England Journal of Higher Education" ("NEJHE") Executive Editor John O. Harney had the chance to catch up with Lasell College President Michael Alexander about the small Newton, Massachusetts, college's plans to challenge the higher education business model. The interview is presented in this article.

  6. Goodbye Michael Gove

    ERIC Educational Resources Information Center

    Bassey, Michael

    2014-01-01

    Michael Gove was Secretary of State for Education from May 2010 to July 2014 when the Prime Minister sacked him. With strong opinions arising from his own life experiences and outstanding energy for reform, but severely limited understanding of education and a refusal to consult teachers and other professionals, he imposed half-baked ideas on the…

  7. Michael Polanyi on the Education and Knowledge of Scientists.

    ERIC Educational Resources Information Center

    Jacobs, Struan

    2000-01-01

    Explains why teachers addressing the nature of science should know the work of Michael Polanyi. Outlines Polanyi's intellectual career and examines his ideas on the education of scientists, research, and knowledge. Polanyi presaged Kuhn, Feyerabend, and the constructivists, yet insisted that science produces true knowledge about reality. (Contains…

  8. 76 FR 21406 - Michael J. Aruta, M.D.; Decision and Order

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-15

    ... DEPARTMENT OF JUSTICE Drug Enforcement Administration [Docket No. 10-40] Michael J. Aruta, M.D.; Decision and Order ACTION: Correction. On Thursday, April 7, 2011, the Drug Enforcement Administration published the above-titled Decision and Order, as well as the Decision of the Administrative Law Judge (76...

  9. Encyclopedia of Life

    Science.gov Websites

    Movement who took this action. Green Movement added text to "Guacharaca caribeña " on " action. Maggie Whitson added "Chorizema" to the collection "Cool Flowers". about 3 hours ago Reply Profile picture of C. Michael Hogan who took this action. C. Michael Hogan marked the

  10. Synthesis of pyroglutamic acid derivatives via double michael reactions of alkynones.

    PubMed

    Scansetti, Myriam; Hu, Xiangping; McDermott, Benjamin P; Lam, Hon Wai

    2007-05-24

    In the presence of substoichiometric quantities of potassium tert-butoxide and an additional metal salt, amide-tethered diacids undergo double Michael reactions with alkynones to provide highly functionalized pyroglutamic acid derivatives. The metal salt was found to play an important role in improving the diastereoselectivities of the reactions.

  11. Michael Griffin Oath Of Office

    NASA Image and Video Library

    2005-04-14

    John H. Marburger, Science Adviser to the President and Director of the Office of Science and Technology Policy (OSTP), left, talks with NASA Administrator Michael Griffin, center, while his wife Rebecca and daughter Katie look on following his swearing-in, Thursday, April 14, 2005, in Washington. Photo Credit: (NASA/Renee Bouchard)

  12. File System Virtual Appliances: Portable File System Implementations

    DTIC Science & Technology

    2010-04-01

    com- puting. Santa Cruz, CA, 1994. [12] Michael Eisler , Peter Corbett, Michael Kazar, Daniel S. Nydick, and Christopher Wagner. Data ontap gx: a...fuse.sourceforge.net. [15] R. A. Gingell, J. P. Moran, and W. A. Shannon. Virtual memory architecture in sunos. USENIX ATC, pages 81–94, 1987 . [16

  13. 78 FR 25273 - Determination and Declaration Regarding Emergency Use of in Vitro Diagnostics for Detection of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-30

    ... Respiratory Protection Devices, and Respiratory Support Devices signed by then Secretary Michael Leavitt on... Act Declaration for Pandemic Influenza Diagnostics, Personal Respiratory Protection Devices, and Respiratory Support Devices signed by then Secretary Michael Leavitt on December 17, 2008. Notice of the EUAs...

  14. The NATO Special Operations Forces Transformation Initiative: Opportunities and Challenges

    DTIC Science & Technology

    2009-03-01

    reality in the starkest possible terms when British Lieutenant General Sir Michael Jackson refused to comply with the orders of the then-SACEUR...http://www.strategicstudiesinstitute.army.mil/pdffiles/PUB889.pdf (accessed 15 November 2008). 58 General Sir Michael Jackson , “My Clash With NATO

  15. Human-Computer System Development Methodology for the Dialogue Management System.

    DTIC Science & Technology

    1982-05-01

    methodologies [HOSIJ78] are given below: I. The Michael Jackson Methodology [JACKM75] 2. The Warnier-Orr Methodolgy [HOSIJ78] 3. SADT (Structured...All the mentioned methodologies use top-down development strategy. The first two methodologies above ( Michael Jackson and Warnier-Orr) use data as the

  16. The Use of Portfolios in Leadership Education

    ERIC Educational Resources Information Center

    Olsen, Paul E.

    2009-01-01

    This paper discusses the benefits of using student portfolios in undergraduate leadership education at Saint Michael's College. There appears to be a natural link between the use of portfolios as a tool to facilitate and document leadership growth and development. The Business Administration and Accounting Department at Saint Michael's College…

  17. Michael Griffin Senate Hearing

    NASA Image and Video Library

    2005-05-17

    Senator Trent Lott, R-Miss., questions NASA Administrator Dr. Michael Griffin during his appearance in front of the Senate Commerce Committee Science and Space Subcommittee hearing on Human Space Flight: The Space Shuttle and Beyond, Wednesday, May 18, 2005, in the Russell Senate Office Building on Capitol Hill in Washington. Photo Credit: (NASA/Bill Ingalls)

  18. Michael Griffin Senate Hearing

    NASA Image and Video Library

    2005-05-17

    NASA Administrator Dr. Michael Griffin is seen prior to his appearance in front of the Senate Commerce Committee Science and Space Subcommittee hearing on Human Space Flight: The Space Shuttle and Beyond, Wednesday, May 18, 2005, in the Russell Senate Office Building on Capitol Hill in Washington. Photo Credit: (NASA/Bill Ingalls)

  19. Q & A with Ed Tech Leaders: Interview with J. Michael Spector

    ERIC Educational Resources Information Center

    Shaughnessy, Michael F.; Fulgham, Susan M.

    2015-01-01

    J. Michael Spector's academic preparation was in philosophy--epistemology and logic, primarily. His dissertation was on skepticism in modern philosophy, and that led him to a deep-seated appreciation for classical skepticism. The word "skeptic" is derived from the Greek word "skepsis," which means investigation. While the…

  20. Comments on Michael (1993): Establishing Operations

    ERIC Educational Resources Information Center

    Moore, J.

    2013-01-01

    The present comments concern Michael's concept of motivative variables, and the implications of that concept for our understanding of the nature of reinforcement as well as the extinction of responses maintained through positive and negative reinforcement. We note that both extinction and altering motivative variables decrease responding, but…

  1. Michael Faraday's Bicentenary.

    ERIC Educational Resources Information Center

    Williams, L. Pearce; And Others

    1991-01-01

    Six articles discuss the work of Michael Faraday, a chemist whose work revolutionized physics and led directly to both classical field and relativity theory. The scientist as a young man, the electromagnetic experiments of Faraday, his search for the gravelectric effect, his work on optical glass, his laboratory notebooks, and his creative use of…

  2. Asymmetric Michael Addition Mediated by Chiral Ionic Liquids

    PubMed Central

    Suzuki, Yumiko

    2018-01-01

    Chiral ionic liquids with a focus on their applications in asymmetric Michael additions and related reactions were reviewed. The examples were classified on the basis of the mode of asymmetric induction (e.g., external induction/non-covalent interaction or internal induction/covalent bond formation), the roles in reactions (as a solvent or catalyst), and their structural features (e.g., imidazolium-based chiral cations, other chiral oniums; proline derivatives). Most of the reactions with high chiral induction are Michael addition of ketones or aldehydes to chalcones or nitrostyrenes where proline-derived chiral ionic liquids catalyze the reaction through enamine/ iminium formation. Many reports demonstrate the recyclability of ionic liquid-tagged pyrrolidines. PMID:29861702

  3. Thiol-ene Michael-type formation of gelatin/poly(ethylene glycol) biomatrices for three-dimensional mesenchymal stromal/stem cell administration to cutaneous wounds

    PubMed Central

    Xu, Kedi; Cantu, David Antonio; Fu, Yao; Kim, Jaehyup; Zheng, Xiaoxiang; Hematti, Peiman; Kao, W. John

    2013-01-01

    Mesenchymal stromal/stem cells (MSCs) are considered promising cellular therapeutics in the fields of tissue engineering and regenerative medicine. MSCs secrete high concentrations of immunomodulatory cytokines and growth factors, which exert paracrine effects on infiltrating immune and resident cells of the wound microenvironment that could favorably promote healing after acute injury. However, better spatial delivery and improved retention at the site of injury are two factors that could improve the clinical application of MSCs. In this study, we utilized thiol-ene Michael-type addition for rapid encapsulation of MSCs within a gelatin/poly(ethylene glycol) biomatrix; this biomatrix was also applied as a provisional dressing to full-thickness wounds in Sprague-Dawley rats. The three-way interaction of MSCs, gelatin/poly(ethylene glycol) biomatrices, and host immune cells and adjacent resident cells of the wound microenvironment favorably modulated wound progression and host response. In this model we observed attenuated immune cell infiltration, lack of foreign giant cell (FBGC) formation, accelerated wound closure and re-epithelialization, as well as enhanced neovascularization and granulation tissue formation by 7 days. The MSC-entrapped gelatin/poly(ethylene glycol) biomatrix localized the presentation of MSCs adjacent to the wound microenvironment and thus, mediated early resolution of inflammatory events and facilitated proliferative phases in wound healing. PMID:23811217

  4. Activation of Nrf2 target enzymes conferring protection against oxidative stress in PC12 cells by ginger principal constituent 6-shogaol.

    PubMed

    Peng, Shoujiao; Yao, Juan; Liu, Yaping; Duan, Dongzhu; Zhang, Xiaolong; Fang, Jianguo

    2015-08-01

    Natural compounds containing phenoxyl groups and/or Michael acceptor units appear to possess antioxidant and cytoprotective properties. The ginger principal constituent 6-shogaol (6-S) represents one of such compounds. In this study, we reported that 6-S efficiently scavenges various free radicals in vitro, and displays remarkable cytoprotection against oxidative stress-induced cell damage in the neuron-like rat pheochromocytoma cell line, PC12 cells. Pretreatment of PC12 cells with 6-S significantly upregulates a series of phase II antioxidant molecules, such as glutathione, heme oxygenase 1, NAD(P)H: quinone oxidoreductase 1, thioredoxin reductase 1, and thioredoxin 1. A mechanistic study revealed that 6-S enhanced the translocation of Nrf2 from the cytosol to the nucleus and knockdown of Nrf2 abolished such protection, indicating that this cytoprotection is mediated by the activation of the transcription factor Nrf2. Another ginger constituent 6-gingerol (6-G), having a similar structure of 6-S but lacking the alpha,beta-unsaturated ketone structure (Michael acceptor moiety), failed to shelter PC12 cells from oxidative stress. Our results demonstrate that 6-S is a novel small molecule activator of Nrf2 in PC12 cells, and suggest that 6-S might be a potential candidate for the prevention of oxidative stress-mediated neurodegenerative disorders.

  5. Making Constructive Simulations Relevant for Today’s Fight

    DTIC Science & Technology

    2010-03-08

    Afghanistan. Dr. Michael Vlahos , a member of the National Security Assessment team of the National Security Analysis Department (NSAD) at the Johns Hopkins...www.carlisle.army.mil/DIME/documents/Szepesy%5B1%5D.pdf (accessed February 23, 2010). 20 13 Michael Vlahos , Culture’s Mask: War & Change after Iraq (Laurel

  6. Admiral Raymond A. Spruance: Lessons in Adaptation from the Pacific

    DTIC Science & Technology

    2010-04-30

    Association of the Class of 1907, 342. 54 Hough, 237. 55 Vlahos , Michael. The Blue Sword: The Naval War College and the American Mission, 1919-1941...Warfare: Theory and Practice. Newport, RI: U.S. Naval War College, 2009. Vlahos , Michael. The Blue Sword: The Naval War College and the American

  7. The Politics of Education Revisited: Anthony Crosland and Michael Gove in Historical Perspective

    ERIC Educational Resources Information Center

    Finn, Mike

    2015-01-01

    This article traces continuity and change in the governance of British education through the comparison of two ministers, Anthony Crosland and Michael Gove. Taking Maurice Kogan's seminal "The Politics of Education" as the point of departure, the article highlights the role of political ideology in large-scale educational change, taking…

  8. From Gouldner to Gramsci: The Making of Michael Apple's "Ideology and Curriculum"

    ERIC Educational Resources Information Center

    Gottesman, Isaac

    2012-01-01

    Michael Apple's "Ideology and Curriculum", published in 1979, helped initiate a broad turn in the field of education in the United States to Marxist thought as a lens through which to analyze the relationship between school and society. This classic text continues to inform scholarship in the field. While "Ideology" has…

  9. A Good Time: A Conversation with C. Michael Nelson

    ERIC Educational Resources Information Center

    Zabel, Robert; Kaff, Marilyn; Teagarden, Jim

    2015-01-01

    C. Michael Nelson began his special education career as a teacher of adolescents with learning and behavior disorders. He has worked as a child psychologist and as a professor with the Department of Special Education and Rehabilitation Counseling at the University of Kentucky. He coordinated the graduate Personnel Preparation Program for Teachers…

  10. Michael Duane after Risinghill: Rise and Fall of an Educational Celebrity

    ERIC Educational Resources Information Center

    Limond, David

    2005-01-01

    In this article an attempt is made to examine the continuing implications of the operation and closure of London's Risinghill school, a co-educational comprehensive extant from 1960 to 1965. It is suggested that Risinghill's controversial headteacher, Michael Duane (1915-1997), was an educational celebrity and folk hero amongst teachers and in…

  11. Aza-Michael Reaction for an Undergraduate Organic Chemistry Laboratory

    ERIC Educational Resources Information Center

    Nigam, Manisha; Rush, Brittney; Patel, Jay; Castillo, Raul; Dhar, Preeti

    2016-01-01

    A green, aza-Michael reaction is described that can be used to teach undergraduate students conjugate addition of nitrogen nucleophile to an a,ß-unsaturated ester. Students analyze spectral data of the product obtained from the assigned reaction to determine product structure and propose the mechanism of its formation. The experiment requires…

  12. Training and Mastery of Techniques in Wittgenstein's Later Philosophy: A Response to Michael Luntley

    ERIC Educational Resources Information Center

    Stickney, Jeff

    2008-01-01

    Responding to Michael Luntley's article, "Learning, Empowerment and Judgement," the author shows he cannot successfully make the following three moves: (1) dissolve the analytic distinction between learning by training and learning by reasoning, while advocating the latter; (2) diminish the role of training in Wittgenstein's philosophy, nor…

  13. Gender Relations and Sexual Harassment in the Workplace: Michael Crichton's "Disclosure" as a Teaching Tool.

    ERIC Educational Resources Information Center

    Comer, Debra R.; Cooper, Elizabeth A.

    1998-01-01

    Describes how to use Michael Crichton's novel "Disclosure" and the film based on it for class discussions of such issues as what constitutes sexual harassment, harassment of men, relationship between sexual harassment and power, organizational responses to harassment, and gender differences in career advancement tactics. (SK)

  14. Double hetero-Michael addition of N-substituted hydroxylamines to quinone monoketals: synthesis of bridged isoxazolidines.

    PubMed

    Yin, Zhiwei; Zhang, Jinzhu; Wu, Jing; Liu, Che; Sioson, Kate; Devany, Matthew; Hu, Chunhua; Zheng, Shengping

    2013-07-19

    A general synthesis of bridged isoxazolidines from a double hetero-Michael addition of N-substituted hydroxylamines to quinone monoketals has been developed. The different addition order of N-benzylhydroxylamine and N-Boc hydroxylamine is also discussed. Moreover, the various functionalities in the isoxazolidine products allow facile derivatization.

  15. HIGHLY DISATEREOSELECTIVE MICHAEL ADDITION OF FLAVANONE TO ITS CHALCONE PRECURSOR UNDER SOLVENT-FREE CONDITIONS USING MICROWAVES [POSTER

    EPA Science Inventory

    Substituted 2'-hydroxychalcones were found to give an equilibrium mixture of the starting chalcone and the corresponding flavanone inf 4.6-1:3 ratio in the presence of DBU gave two hitherto unknown diasteromeric dimers in a highly diastereoselective Michael addition of the carban...

  16. A Bibliographic Tribute to Jack Michael

    ERIC Educational Resources Information Center

    Esch, Barbara E.; Esch, John W.

    2016-01-01

    "In the late 1950's, Jack Michael, a bright but irritating young psychology instructor, moved from the Universities of Kansas to Houston to Arizona State. Along the way he befriended two nontraditional students, protected them through their Ph.D. programs, and turned them loose on the world: Teodoro Ayllon…and Montrose Wolf…" (Risley,…

  17. Educational Implications of Michael Fishbane's "Sacred Attunement: A Jewish Theology"

    ERIC Educational Resources Information Center

    Marom, Daniel

    2008-01-01

    This article posits Michael Fishbane's Judaic scholarship as a prime resource for Jewish education. The link between the two fields can be made through a translation of the theological underpinnings of Fishbane's insights into Judaism to educational purposes and practices. Initial work with Jewish educators on establishing this link encouraged…

  18. Broadening the Debate: Comments on Michael J. Feuer's "Moderating the Debate"

    ERIC Educational Resources Information Center

    Robertson, Emily

    2009-01-01

    In "Moderating the Debate: Rationality and the Promise of American Education", Michael Feuer argues that insights from cognitive science and the theory of bounded rationality can help us understand why educational policy makers overreach in seeking optimal solutions to educational problems. In this essay, Emily Robertson argues that cognitive…

  19. What Works, Works Everywhere: Q&A with Michael Barber

    ERIC Educational Resources Information Center

    Crow, Tracy

    2009-01-01

    This article presents an interview with Michael Barber, a partner at McKinsey & Company, leading its global education practice. He has been working on major challenges of performance, organization, and reform in government and the public services, especially education, in the U.S., U.K., and other countries. Barber was instrumental in preparing…

  20. The Power of the Powerless

    ERIC Educational Resources Information Center

    Welch, Cay

    2009-01-01

    This is a Pittsburgh story. It is about a boy named Michael Charles Metil--a boy that transformed many lives, including the author's. While visiting grandparents over the Christmas holiday in Latrobe, Pennsylvania in 1993, Michael became sick. He was lethargic, vomiting, and had some diarrhea. Little did his parents realize how very sick he was,…

  1. Reframing Michael Scott: Exploring Inappropriate Workplace Communication

    ERIC Educational Resources Information Center

    Schaefer, Zachary A.

    2010-01-01

    Individuals who work in professional settings interact with others who may exhibit a variety of cultural beliefs and decision-making approaches. Page (2007) argues that cognitive diversity (i.e., how people approach and attempt to solve problems) is a vital asset in effective organizations. Michael Scott, who portrays the inept main character on…

  2. Balancing Act: The U. S. Military’s Reliance on Contractors to Fulfill Operational-Level Logistical Requirements

    DTIC Science & Technology

    2014-05-15

    Military Sealift Command. Combat Logistics Force (PM1), 1. 40 Ibid. 41 Michael Marquez, Richard Rayos, and John Mercado . Standard Port-Visit Forecasting...Series no. 8 (2012). Marquez, Michael, John Mercado , and Richard Rayos. Standard Port-Visit Forecasting Model for U.S. Navy Husbanding

  3. Michael Hand, Indoctrination and the Inculcation of Belief

    ERIC Educational Resources Information Center

    Tan, Charlene

    2004-01-01

    In 'Religious Upbringing Reconsidered,' Michael Hand revisits the debate on the right of parents to give their children a religious upbringing in a liberal context. According to him, the logical difficulty lies in the fact that parents cannot both impart religious beliefs and avoid indoctrination. While Peter Gardner and Jim Mackenzie have…

  4. The Educational Philosophies of Mordecai Kaplan and Michael Rosenak: Surprising Similarities and Illuminating Differences

    ERIC Educational Resources Information Center

    Schein, Jeffrey; Caplan, Eric

    2014-01-01

    The thoughts of Mordecai Kaplan and Michael Rosenak present surprising commonalities as well as illuminating differences. Similarities include the perception that Judaism and Jewish education are in crisis, the belief that Jewish peoplehood must include commitment to meaningful content, the need for teachers to teach from a position of…

  5. Courtside: Gifted Irony?

    ERIC Educational Resources Information Center

    Zirkel, Perry A.

    2005-01-01

    During the 2002-03 school year, Michael B., Rebecca D., and Aldo V. were eighth-graders at the Regional Gifted Center program at the Beaubien School in the Chicago school system. In February, the Beaubien School held an annual contest for eighth-graders to determine the design for the class T-shirt. Michael was disappointed that his design did not…

  6. C. P. Snow's "The Two Cultures": Michael Polanyi's Response and Context

    ERIC Educational Resources Information Center

    Jacobs, Struan

    2011-01-01

    C. P. Snow's "The Two Cultures" controversially contrasted science and literature, suggesting that neither scientists nor literary intellectuals have much in common with, and seldom bother speaking to, the other. Responding to Snow, Michael Polanyi argued that specialization has made modern culture, not twofold but manifold. In his major work,…

  7. Against Dogma: A Reply to Michael Swan.

    ERIC Educational Resources Information Center

    Widdowson, H. G.

    1985-01-01

    Replies to two articles by Michael Swan entitled "A Critical Look at the Communicative Approach." Argues that Swan presents a distorted version of the communicative approach so as to present his own ideas more effectively and that he fails to offer evidence for his position on the practice of English language teaching. (SED)

  8. The U.S.-Japan Alliance: Review of the Guidelines for Defense Cooperation

    DTIC Science & Technology

    2015-03-01

    Cooperation: Process and Historical Impact, Michael J. Green and Koji Murata concluded that the guidelines failed to establish a clear understanding...Japan-U.S. Security Consultative Committee, November 27, 1978, available at <http://fas.org/news/japan/sisin1e.htm>. 4 Michael J. Green and Koji Murata

  9. Polymer solutions

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Krawczyk, Gerhard Erich; Miller, Kevin Michael

    2011-07-26

    There is provided a method of making a polymer solution comprising polymerizing one or more monomer in a solvent, wherein said monomer comprises one or more ethylenically unsaturated monomer that is a multi-functional Michael donor, and wherein said solvent comprises 40% or more by weight, based on the weight of said solvent, one or more multi-functional Michael donor.

  10. 78 FR 19149 - Small Generator Interconnection Agreements and Procedures; Supplemental Notice of Workshop

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-29

    ..., National Grid (Edison Electric Institute) [rtarr8] Michael Sheehan, P.E., Keyes, Fox & Wiedman L.L.P... Association of Regulatory Utility Commissioners [rtarr8] Sky Stanfield, Attorney, Keyes, Fox & Wiedman L.L.P... Policy, National Grid (Edison Electric Institute) [rtarr8] Michael Sheehan, P.E., Keyes, Fox & Wiedman L...

  11. On the Distinction between Positive and Negative Reinforcement

    ERIC Educational Resources Information Center

    Iwata, Brian A.

    2006-01-01

    In this article, the author presents his views on Michael's (1975) and Baron and Galizio's (2005) arguments on eliminating the distinction between positive and negative reinforcement. He first discusses Michael's concept of these two types of operations and contrasts it with the notions of Baron and Galizio. The author provides the readers his own…

  12. Dialogue on Modernity and Modern Education in Dispute

    ERIC Educational Resources Information Center

    Baker, Michael; Peters, Michael A.

    2012-01-01

    This is a dialogue or conversation between Michael Baker (MB) and Michael A. Peters (MP) on the concept of modernity and its significance for educational theory. The dialogue took place originally as a conversation about a symposium on modernity held at the American Educational Studies Association meeting 2010. It was later developed for…

  13. Michael Driver: A Career Life to Remember

    ERIC Educational Resources Information Center

    Sundby, Dianne; Derr, C. Brooklyn

    2007-01-01

    Purpose: The purpose of this paper is to present a retrospective of the career life of Michael Driver, from the time of his Princeton graduate studies and early faculty years at Purdue University through the over three decades he spent at USC. Design/methodology/approach: The history and development of his theoretical and research interests are…

  14. N-heterocyclic carbene-catalyzed tandem aza-benzoin/Michael reactions: on site reversal of the reactivity of N-Boc imines.

    PubMed

    Wu, Ke-Jia; Li, Gong-Qiang; Li, Yi; Dai, Li-Xin; You, Shu-Li

    2011-01-07

    A tandem NHC-catalyzed aza-benzoin/Michael reaction has been developed as a method to efficiently produce dihydroindenones and pyrrolidinone-containing tricycles. The novel reaction pattern involves tert-butyl aryl(tosyl)methylcarbamates reacting as both electrophile and nucleophile on the same carbon.

  15. A Stability Police Force for the United States: Justification and Options for Creating U.S. Capabilities

    DTIC Science & Technology

    2009-01-01

    Investigative Analysis, Ottawa: Royal Canadian Mounted Police, 2007; John E. Eck , Spencer Chainey, James G. Cameron , Michael Leitner, and Ronald E. Wilson...Kuwait,” Parameters, Vol. 21, No. 4, Winter 1991–1992. Eck , John E., Spencer Chainey, James G. Cameron , Michael Leitner, and Ronald E. Wilson

  16. Tweeting Prayers and Communicating Grief over Michael Jackson Online

    ERIC Educational Resources Information Center

    Sanderson, Jimmy; Cheong, Pauline Hope

    2010-01-01

    Death and bereavement are human experiences that new media helps facilitate alongside creating new social grief practices that occur online. This study investigated how people's postings and tweets facilitated the communication of grief after pop music icon Michael Jackson died. Drawing on past grief research, religion, and new media studies, a…

  17. European Adaptation to Expeditionary Warfare: Implications for the U.S. Army

    DTIC Science & Technology

    2002-11-01

    than any other recent operation, highlighted Europe’s inability to deploy ground forces rapidly. General Sir Michael Jackson was only able to deploy...Security, Vol. 9, No. 4, Winter 2000, pp. 31-44. 48. Lieutenant-General Sir Michael Jackson , “KFOR: The Inside Story,” The RUSI Journal, Vol. 145, No

  18. Q&A: Michael Honey

    ERIC Educational Resources Information Center

    Helicher, Karl

    2007-01-01

    The mid-1960s saw civil rights victories in Congress during Lyndon B. Johnson's presidency. In "Going Down Jericho Road," Michael Honey wrote how Martin Luther King Jr.'s final focus showed that the struggle for black and working class parity continued. The 1968 Memphis sanitation workers strike was a gritty struggle won in the streets by a host…

  19. Michael Griffin Senate Confirmation Hearing

    NASA Image and Video Library

    2005-04-12

    Dr. Michael Griffin testifies, Tuesday, April 12, 2005, during his confirmation hearing before the U.S. Senate Commerce Committee at the Russell Senate Office Building in Washington. If confirmed, Griffin, who currently heads the space department at the Johns Hopkins University Applied Physics Laboratory will become NASA's 11th administrator. Photo Credit (NASA/Renee Bouchard)

  20. Michael Griffin Senate Confirmation Hearing

    NASA Image and Video Library

    2005-04-11

    Dr. Michael Griffin testifies, Tuesday, April 12, 2005, during his confirmation hearing before the U.S. Senate Commerce Committee at the Russell Senate Office Building in Washington. If confirmed, Griffin, who currently heads the space department at the Johns Hopkins University Applied Physics Laboratory will become NASA's 11th administrator. Photo Credit (NASA/Renee Bouchard)

  1. Michael Griffin Senate Hearing

    NASA Image and Video Library

    2005-05-17

    U.S. Senator Bill Nelson. R-Fla., questions NASA Administrator Dr. Michael Griffin during his appearance in front of the Senate Commerce Committee Science and Space Subcommittee hearing on Human Space Flight: The Space Shuttle and Beyond, Wednesday, May 18, 2005, in the Russell Senate Office Building on Capitol Hill in Washington. Photo Credit: (NASA/Bill Ingalls)

  2. Attending to hidden realities: contributions from the work of Michael Polanyi to supervision in pastoral care and counseling.

    PubMed

    Rodgerson, Thomas E

    2008-01-01

    In this article, the author suggests that concepts from the work of Michael Polanyi--such as the tacit dimension, subsidiary awareness, and commitment to a yet unrevealed, hidden reality--provide a theoretical basis for understanding the unique formation involved in pastoral care and counseling supervision.

  3. A celebration of mechanics: from nano to macro. The J. Michael T. Thompson Festschrift issue.

    PubMed

    Elishakoff, Isaac

    2013-06-28

    This Theme Issue is dedicated to the topic 'Mechanics: from nano to macro' and marks the 75th birthday of Dr J. Michael T. Thompson, Fellow of the Royal Society, whose current affiliations are as follows: (i) Honorary Fellow, Department of Applied Mathematics and Theoretical Physics, Centre for Mathematical Sciences, University of Cambridge; (ii) Emeritus Professor of Nonlinear Dynamics, Department of Civil, Environmental and Geomatic Engineering, University College London; and (iii) Professor of Theoretical and Applied Dynamics (Distinguished Sixth Century Chair, part-time), University of Aberdeen. He also serves as Chairman of the Board of Directors at ES-Consult (consulting engineers) in Copenhagen, Denmark. The pertinent question that arises from the very start is: should we first salute Michael and then describe the Theme Issue, or vice versa? Indeed, according to Blaise Pascal (1623-1662), the last thing one discovers in composing a work is what to put first. I would like to take the liberty of deviating from the tradition of the Philosophical Transactions and start with the tribute to Michael; after all he is the prime cause of this Theme Issue.

  4. Acid-Activatable Michael-Type Fluorescent Probes for Thiols and for Labeling Lysosomes in Live Cells.

    PubMed

    Dai, Chun-Guang; Du, Xiao-Jiao; Song, Qin-Hua

    2015-12-18

    A Michael addition is usually taken as a base-catalyzed reaction. Most fluorescent probes have been designed to detect thiols in slightly alkaline solutions (pH 7-9). The sensing reactions of almost all Michael-type fluorescent probes for thiols are faster in a high pH solution than in a low pH solution. In this work, we synthesized a series of 7-substituted 2-(quinolin-2-ylmethylene)malonic acids (QMAs, substituents: NEt2, OH, H, Cl, or NO2) and their ethyl esters (QMEs) as Michael-type fluorescent probes for thiols. The sensing reactions of QMAs and QMEs occur in distinct pH ranges, pH < 7 for QMAs and pH > 7 for QMEs. On the basis of experimental and theoretic studies, we have clarified the distinct pH effects on the sensing reactivity between QMAs and QMEs and demonstrated that two QMAs (NEt2, OH) are highly sensitive and selective fluorescent probes for thiols in acidic solutions (pH < 7) and promising dyes that can label lysosomes in live cells.

  5. KENNEDY SPACE CENTER, FLA. -- From left, a United Space Alliance (USA) technician briefs NASA Deputy Program Manager of the Space Shuttle Program Michael Wetmore, USA Vice President and Space Shuttle Program Manager Howard DeCastro, and NASA Deputy Associate Administrator for Space Station and Shuttle Programs Michael Kostelnik on the use of cold plates in Orbiter Processing Facility Bay 2. NASA and USA Space Shuttle program management are participating in a leadership workday. The day is intended to provide management with an in-depth, hands-on look at Shuttle processing activities at KSC.

    NASA Image and Video Library

    2003-12-19

    KENNEDY SPACE CENTER, FLA. -- From left, a United Space Alliance (USA) technician briefs NASA Deputy Program Manager of the Space Shuttle Program Michael Wetmore, USA Vice President and Space Shuttle Program Manager Howard DeCastro, and NASA Deputy Associate Administrator for Space Station and Shuttle Programs Michael Kostelnik on the use of cold plates in Orbiter Processing Facility Bay 2. NASA and USA Space Shuttle program management are participating in a leadership workday. The day is intended to provide management with an in-depth, hands-on look at Shuttle processing activities at KSC.

  6. Hexamethoxylated Monocarbonyl Analogues of Curcumin Cause G2/M Cell Cycle Arrest in NCI-H460 Cells via Michael Acceptor-Dependent Redox Intervention.

    PubMed

    Li, Yan; Zhang, Li-Ping; Dai, Fang; Yan, Wen-Jing; Wang, Hai-Bo; Tu, Zhi-Shan; Zhou, Bo

    2015-09-09

    Curcumin, derived from the dietary spice turmeric, holds promise for cancer prevention. This prompts much interest in investigating the action mechanisms of curcumin and its analogues. Two symmetrical hexamethoxy-diarylpentadienones (1 and 2) as cucumin analogues were reported to possess significantly enhanced cytotoxicity compared with the parent molecule. However, the detailed mechanisms remain unclear. In this study, compounds 1 and 2 were identified as the G2/M cell cycle arrest agents to mediate the cytotoxicity toward NCI-H460 cells via Michael acceptor-dependent redox intervention. Compared with curcumin, they could more easily induce a burst of reactive oxygen species (ROS) and collapse of the redox buffering system. One possible reason is that they could more effectively target intracellular TrxR to convert this antioxidant enzyme into a ROS promoter. Additionally, they caused up-regulation of p53 and p21 and down-regulation of redox-sensitive Cdc25C along with cyclin B1/Cdk1 in a Michael acceptor- and ROS-dependent fashion. Interestingly, in comparison with compound 2, compound 1 displayed a relatively weak ability to generate ROS but increased cell cycle arrest activity and cytotoxicity probably due to its Michael acceptor-dependent microtubule-destabilizing effect and greater GST-inhibitory activity, as well as its enhanced cellular uptake. This work provides useful information for understanding Michael acceptor-dependent and redox-mediated cytotoxic mechanisms of curcumin and its active analogues.

  7. Little Mosie from the Margaree: A Biography of Moses Michael Coady.

    ERIC Educational Resources Information Center

    Welton, Michael R.

    This book examines the life of the Reverend Moses Michael Coady (1890-1959), a Roman Catholic priest who led the Antigonish Movement. During the Antigonish Movement, residents of the small maritime town of Antigonish, Nova Scotia, worked to achieve a nonviolent alternative to communism and fascism and to effect the social and economic…

  8. 78 FR 68102 - Atomic Safety and Licensing Board; In the Matter of Nuclear Innovation North America LLC (South...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-13

    ...] Atomic Safety and Licensing Board; In the Matter of Nuclear Innovation North America LLC (South Texas... Administrative Judges: Michael M. Gibson, Chairman, Dr. Gary S. Arnold, Dr. Randall J. Charbeneau. The Atomic... follows: Mail: Administrative Judge Michael M. Gibson, Atomic Safety and Licensing Board Panel, Mail Stop...

  9. The United Kingdom Children's Laureate: The Story so Far

    ERIC Educational Resources Information Center

    Tucker, Nicholas

    2014-01-01

    Britain's Children's Laureate Scheme has now been running for 14 years. This article asks Quentin Blake, Anne Fine, Michael Morpurgo, Jacqueline Wilson, Anthony Browne, Michael Rosen and Julia Donaldson for their views on their own experience of taking up this post. It concludes with a discussion of the recurring issues raised by these Laureates…

  10. A tribute to Michael R. Raupach for contributions to aeolian fluid dynamics

    USDA-ARS?s Scientific Manuscript database

    Since the early work of Bagnold in the 1940s, aeolian research has grown to become a major integral part of earth-system studies. Many individuals have contributed to this development, and Dr. Michael R. Raupach (MR2, 1950 – 2015) was one of the most outstanding. MR2 worked for about a decade (1985 ...

  11. Defining Deviance: Sex, Science, and Delinquent Girls, 1890-1960

    ERIC Educational Resources Information Center

    Clemente, Michael

    2013-01-01

    This article presents a review on "Defining deviance: sex, science, and delinquent girls, 1890-1960," by Michael A. Rembis. This is the first book by Michael A. Rembis, an Associate Professor and Director of the Center for Disability Studies at the University of Buffalo. Drawing on thousands of case files from the Illinois State Training School in…

  12. Cloud Migration Experiment Configuration and Results

    DTIC Science & Technology

    2017-12-01

    ARL-TR-8248 ● DEC 2017 US Army Research Laboratory Cloud Migration Experiment Configuration and Results by Michael De Lucia...or reconstruction of the document. ARL-TR-8248 ● DEC 2017 US Army Research Laboratory Cloud Migration Experiment Configuration...and Results by Michael De Lucia Computational and Information Sciences Directorate, ARL Justin Wray and Steven S Collmann ICF International

  13. Michael Young's "The Rise of the Meritocracy": A Philosophical Critique

    ERIC Educational Resources Information Center

    Allen, Ansgar

    2011-01-01

    This paper examines Michael Young's 1958 dystopia, "The Rise of the Meritocracy". In this book, the word "meritocracy" was coined and used in a pejorative sense. Today, however, meritocracy represents a positive ideal against which we measure the justice of our institutions. This paper argues that, when read in the twenty-first century, Young's…

  14. Freedom of Information Act Requests: Six Keys to Handling Them

    DTIC Science & Technology

    2016-01-01

    Defense AT&L: January–February 2016 50 Freedom of Information Act Requests Six Keys to Handling Them Michael A. Rodgers Rodgers is a professor of...crucial mission tasks. Understanding and using the six steps and keys provided above will free you from FOIA-induced distractions. The author can be contacted at michael.rodgers@dau.mil.

  15. Q & A with Ed Tech Leaders: Interview with Michael W. Allen

    ERIC Educational Resources Information Center

    Shaughnessy, Michael F.

    2014-01-01

    Michael W. Allen, the Chairman and CEO of Allen Interactions, is an architect of interactive multimedia learning and is recognized for his many insights, inventions, and presentations. With over 50 years of experience in e-learning, both in academic and corporate settings, he is known for his role in creating Authorware and overseeing the work of…

  16. Gulliver's Travels: Michael Moore the Explorer in "Who to Invade Next"

    ERIC Educational Resources Information Center

    Beck, Bernard

    2016-01-01

    America is identified as a nation of immigrants. These immigrants are thought to be the source of its subcultures. It is also a nation of individual explorers and inventors. Their activities are also a source of diverse subcultures. Many notable movies have made heroes of such innovators in different fields of endeavor. Michael Moore's movie…

  17. Irish Education for the 21st Century. Michael Enright Commemorative Project.

    ERIC Educational Resources Information Center

    Ward, Noel, Ed.; Dooney, Triona, Ed.

    The essays in this collection contribute to the ongoing discussion about the state of Irish education on the threshold of a new century. The various contributors examine issues that will be priorities for education planners in Ireland. These essays have been collected as a tribute to Irish educator and politician Michael Enright. The essays are:…

  18. "Raising Standards" or Reducing Aspirations and Opportunities Still Further? Michael Gove and Examination Reforms

    ERIC Educational Resources Information Center

    Allen, Martin

    2013-01-01

    Well before the examinations grade crisis of 2012, Michael Gove had set out clear intentions for reforming public examinations. Though he claimed to be improving examinations and assessment by replicating practices that took place in high-performing countries and thus improving the ability of the UK economy to "compete", this…

  19. The Benevolent Technocrat: Michael Dukakis' Strategy in the 1988 Presidential Debates.

    ERIC Educational Resources Information Center

    Herbeck, Dale A.

    Michael Dukakis lost the presidential campaign debates of 1988 (or at least failed to capitalize as much as he might have) because he understood the debates to be genuine debates. Consequently, Dukakis acted as a debater generating an image of himself as a "benevolent technocrat," which was an error. It must be pointed out that the…

  20. Wolff-Michael Roth's passibility: at the limits of the constructivist metaphor: a book review

    NASA Astrophysics Data System (ADS)

    Brendel, Michelle

    2014-12-01

    Wolff-Michael Roth deconstructs the preeminent role conceded to constructivism in Science Education and demonstrates how we learn and know through pain, suffering, love or passion. This review explores his book "Passibility: At the Limits of the Constructivist Metaphor" through the eyes of an outsider to the world of science education.

  1. Technique Development Results for the Study of a Novel Dexamethasone Impregnated Bandage Contact Lens in a Rabbit Model After Photorefractive Keratectomy

    DTIC Science & Technology

    2017-10-22

    PRK Inflammation in a Rabbit Model Timothy A. Soekenl, Michael Merkley!, Wesley Brundridgel, Gary Legaultl, Matthew Caldwelll, Joseph Ciolino2...7 .0 Dexamethasone Impregnated Contact Lenses in the Treatment of Post- PRK Inflammation · in a Rabbit Model Timothy A. Soeken 1, Michael Merkley1

  2. Efficient synthesis of optically active 4-nitro-cyclohexanones via bifunctional thiourea-base catalyzed double-Michael addition of nitromethane to dienones.

    PubMed

    Wu, Bin; Liu, Guo-Gui; Li, Mei-Qiu; Zhang, Yong; Zhang, Shao-Yun; Qiu, Jun-Ru; Xu, Xiao-Ping; Ji, Shun-Jun; Wang, Xing-Wang

    2011-04-07

    Thiourea-modified cinchona alkaloids as bifunctional catalysts and a base could catalyze a stepwise [5+1] cyclization of divinyl ketones with nitromethane via double Michael additions, furnishing optically active 4-nitro-cyclohexanones with good yields, excellent diastereoselectivities (>20 : 1) and high enantiomeric ratios (up to 97 : 3).

  3. Defense Innovation Unit Experimental (DIUX): Innovative or Excessive

    DTIC Science & Technology

    2017-04-06

    DIUx, and the short history of DIUx. Innovation principles from authors Vijay Govindarajan, Michael Docherty, and Clayton Christensen are then...innovation principles such as performance engine & innovative team, collective / open innovation, and disruptive technology and its implications – is...various innovation principles drawing primarily from work by authors Vijay Govindarajan and Chris Trimble, Michael Docherty, and Clayton Christenson

  4. Michael's Inform Test of Student Ability (M.I.T.O.S.A.). Tester's Manual.

    ERIC Educational Resources Information Center

    Grafius, Thomas M.

    Michael's Informal Test of Student Ability (MITOSA) is a diagnostic evaluative tool for adult students designed to test nine skills abilities in adult students functioning below a tenth grade level. The nine test sections are approximate reading level, understanding of basic math concepts and symbols, general thinking/reasoning ability, eye-hand…

  5. Moral Education and Education in Altruism: Two Replies to Michael Hand

    ERIC Educational Resources Information Center

    White, John

    2016-01-01

    This article is a critical discussion of two recent papers by Michael Hand on moral education. The first is his "Towards a Theory of Moral Education", published in the "Journal of Philosophy of Education" in 2014 (Volume 48, Issue 4). The second is a chapter called "Beyond Moral Education?" in an edited book of new…

  6. On Happiness and High Achievement: An Interview with Michael Thompson

    ERIC Educational Resources Information Center

    National Association of Independent Schools (NAIS) (NJ), 2006

    2006-01-01

    Michael G. Thompson knows independent schools. He attended them in elementary and secondary school, and has worked in them as a psychologist. He consults with more than 30 schools a year, addressing a myriad of issues related to complex human interaction. He has written often in "Independent School" about everything from understanding the social…

  7. Astronaut C. Michael Foale is briefed on use of Sky Genie

    NASA Technical Reports Server (NTRS)

    1994-01-01

    Astronaut C. Michael Foale, STS-63 mission specialist, is briefed on the use of Sky Genie device by Karin L. Porter. The device would aid in emergency egress operations aboard a troubled Space Shuttle. Porter, an employee of Rockwell International, helps train astronauts in egress procedures at JSC's Shuttle mockup and integration laboratory.

  8. Neuroscientific Investigator of High Mathematical Ability: An Interview with Michael W. O'Boyle

    ERIC Educational Resources Information Center

    Kalbfleisch, M. Layne

    2008-01-01

    This article presents an interview with Michael W. O'Boyle, a neuroscientific investigator of high mathematical ability. O'Boyle is a professor in the Department of Human Development and Family Studies, Texas Tech University, and Adjunct Professor of Pharmacology and Neuroscience, School of Medicine, Texas Tech University Health Sciences Center.…

  9. A Critical Analysis of Michael Tippett's "A Child of Our Time"

    ERIC Educational Resources Information Center

    Vallee, Jean-Sebastien

    2009-01-01

    After more than ten years of thoughtful planning, Michael Tippett (1905-1998) summed up his musical, political, spiritual and philosophical beliefs in his first oratorio, "A Child of Our Time" (1941). Representing the emergence of a new level of confidence and musical maturity for Tippett, the oratorio has become the composer's most widely known…

  10. Michael Griffin Oath Of Office

    NASA Image and Video Library

    2005-04-14

    NASA Administrator Michael Griffin, left, is administered the oath of office by John H. Marburger, right, Science Adviser to the President and Office of Science and Technology Policy Director, during a private ceremony at the Old Executive Office Building, Thursday, April 14, 2005, in Washington, while his wife Rebecca and daughter Katie look on. Photo Credit: (NASA/Renee Bouchard)

  11. A Teacher's Guide to Rerouting the Pipeline

    ERIC Educational Resources Information Center

    Chiariello, Emily

    2013-01-01

    Michael is 15 and repeating the ninth grade. He habitually tilts his chair back and drums annoyingly on his desk with a pencil. This morning, he was doing it--again--while you were trying to teach. What will you do? Responsive teachers shift their reactions in important ways. They adopt a social emotional lens: What does Michael's tapping say…

  12. Software Technology for Adaptable Reliable Systems (STARS) Workshop Held at the Naval Research Laboratory, Washington, DC on April 9-12 1985

    DTIC Science & Technology

    1985-01-01

    paths? .%* vii * * ... * r -. . . .W. -t. ’ PREFACE ......... H*o . .. . ON.........................NT .. . . . . . . . . . . ............ . ........... l...REUSE ................................................ 83 Dr. Bruce A. Burton and Mr. Michael D. Broido REUSABLE COMPONENT DEFINITION (A TUTORIAL...209 Michael R . Miller, Hans L. Hiabereder, and L.O. Keeler REUSABLE SOFTWARE IN SIMULATION APPLICATIONS

  13. An Interview with Michael Horn: Blending Education for High-Octane Motivation

    ERIC Educational Resources Information Center

    Patterson, Gregory A.

    2012-01-01

    Blended learning holds the potential of improving the way we educate students and of making them more motivated. Blended education--the melding of information technology based distance learning with school attendance--is perhaps the best way to educate students for 21st century skills, says Michael Horn in a "Kappan" interview. Horn points out…

  14. Performance Enhancement of the NPS Transient Electromagnetic Scattering Laboratory

    DTIC Science & Technology

    1991-09-01

    MASTER OF SCIENCE IN ELECTRICAL ENGINEERING MASTER OF SCIENCE IN SYSTEMS ENGINEERING (ELECTRONIC WARFARE) from NAVAL POSTGRADUATE S OOL Author: JvAlo...Bresani Approved by: Michael A. Morgan, Thesis Advisor Jeffrey B. Knorr, Second Reader Michael A. Morgan, Chairman, Department of Electrical & Computer...SYSTEM REPRESENTATION ... .......... 13 B. MATHEMATICAL MODEL ......... ..... 15 C. TRANSIENT RESPONSE EVALUATION .. ......... . 17 IV. MEASUREMENT

  15. Facile Iodine-Catalyzed Michael Addition of Indoles to α,α′-Bis(arylmethylene)cyclopentanones: An Efficient Synthesis of E-2-(3-Indolylphenylmethyl)-5-phenylmethylenecyclopentanones

    PubMed Central

    Pal, Rammohan; Das Gupta, Arpita; Mallik, Asok K.

    2012-01-01

    Iodine-catalyzed reaction of indoles with α,α′-bis(arylmethylene)cyclopentanones afforded one diastereomer of the corresponding Michael adducts, namely, E-2-(3-indolylphenylmethyl)-5-phenylmethylenecyclopentanones, in a good yield. The products form a new group of indole derivatives. PMID:24052849

  16. What Work Do the Concepts of "Language" and "Literature" Do for Michael Rosenak?

    ERIC Educational Resources Information Center

    Levisohn, Jon A.

    2014-01-01

    Michael Rosenak uses the twin metaphors of "language" and "literature," borrowed from Oakeshott and Peters, to argue that the goal of education is initiation into a language. This goal transcends the study of literature in that language. It includes, as well, the development of the capacity both to critique literature and to…

  17. Education, Philosophy and Politics: The Selected Works of Michael A. Peters. World Library of Educationalists

    ERIC Educational Resources Information Center

    Peters, Michael A.

    2012-01-01

    In the World Library of Educationalists series, international experts themselves compile career-long collections of what they judge to be their finest pieces--extracts from books, key articles, salient research findings, major theoretical and/practical contributions--so the world can read them in a single manageable volume. Michael A. Peters has…

  18. Subjectivity and Cultural Adjustment in Mathematics Education: A Response to Wolff-Michael Roth

    ERIC Educational Resources Information Center

    Brown, Tony

    2012-01-01

    In this volume, Wolff-Michael Roth provides a critical but partial reading of Tony Brown's book "Mathematics Education and Subjectivity". The reading contrasts Brown's approach with Roth's own conception of subjectivity as derived from the work of Vygotsky, in which Roth aims to "reunite" psychology and sociology. Brown's book, however, focuses on…

  19. Michael Walzer's Politics, in Theory and Practice

    ERIC Educational Resources Information Center

    Williams, Jeffrey J.

    2012-01-01

    Before all the talk about "public intellectuals," Michael Walzer was one. For 50 years, he has gone back and forth between positions at Princeton and Harvard Universities and then at the Institute for Advanced Study, in Princeton, New Jersey, where he is now emeritus. His writings appear regularly in "Dissent" magazine, which he has co-edited for…

  20. Gold (III) Chloride-Catalyzed 6-endo-trig Oxa-Michael Addition Reactions for Diastereoselective Synthesis of Fused Tetrahydropyranones

    PubMed Central

    Ciesielski, Jennifer; Lebœuf, David; Stern, Harry A.

    2013-01-01

    Alkynones were treated with boron trifluoride diethyl etherate to generate β-iodoallenolates, which underwent intramolecular aldol reactions to produce cycloalkenyl alcohols. Diastereoselective oxa-Michael ring closure could then be induced by treatment with a catalytic amount of gold(III) chloride, affording highly functionalized tetrahydropyran-containing ring systems. PMID:24032002

  1. Toward a Global Vision of Gifted Education: An Interview with Michael S. Matthews

    ERIC Educational Resources Information Center

    Henshon, Suzanna E.

    2017-01-01

    Dr. Michael S. Matthews is professor and director of the Academically & Intellectually Gifted graduate programs at the University of North Carolina at Charlotte. He is incoming Coeditor of the "Gifted Child Quarterly" and a member of the Board of Directors of the National Association for Gifted Children. Dr. Matthews also currently…

  2. The Journey Is the Film Is the Journey: Michael Winterbottom's "In This World"

    ERIC Educational Resources Information Center

    Farrier, David

    2008-01-01

    This essay examines Michael Winterbottom's 2002 film "In This World," which follows the journey of two Afghan migrants from Peshawar to London. Winterbottom's preparation involved travelling from London to Peshawar and then in reverse overland as far as Istanbul; he then returned to Peshawar and filmed the same journey using two…

  3. European Adaptation To Expeditionary Warfare: Implications for the U.S. Army

    DTIC Science & Technology

    2002-11-01

    Europe’s inability to deploy ground forces rapidly. General Sir Michael Jackson was only able to deploy nine battalion units on the first day of...31-44. 48. Lieutenant-General Sir Michael Jackson , “KFOR: The Inside Story,” The RUSI Journal, Vol. 145, No. 1, February 2000, p. 15. 31 49. 2308

  4. AFSOF, Integration, and Joint Warfighting: Closing the Training Loop to Force Multiply and Succeed

    DTIC Science & Technology

    2008-04-04

    Succeed 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Maj Michael Jackson 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT...unclassified. Research for the case study involved extensive interviews of involved personnel and document research. 101 Michael Jackson , “Ugly Baby Case

  5. The Increased Role of Regional Organizations in Peacekeeping and Effects on the United Nations Preeminence in Future Peace Operations

    DTIC Science & Technology

    2003-06-06

    Lieutenant General (U.K.) Sir Michael Jackson , the KFOR commander, order the Russians to withdraw from the airport, but Jackson refused to act...1999 that his forces had disarmed fully, and this was confirmed by KFOR Commander Lieutenant General Sir. Michael Jackson (www.afsouth.nato/int.htm

  6. New Computational Framework for the Treatment of Joint Constraints and Connectivity Conditions in Finite Element/Multibody System Algorithms

    DTIC Science & Technology

    2014-03-21

    A. Shabana University of Illinois at Chicago Paramsothy Jayakumar , Michael D. Letherwood, David J. Gorsich U.S. Army TARDEC Disclaimer...ALGORITMS 5a. CONTRACT NUMBER W56hzv-13-c-0032 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Ahmed Shabana; Paramsothy Jayakumar ; Michael

  7. Can Higher Education Foster Economic Growth? A Conference Summary. Chicago Fed Letter. Number 236a

    ERIC Educational Resources Information Center

    Mattoon, Richard H.

    2007-01-01

    On October 30, 2006, the Federal Reserve Bank of Chicago and the Midwest Higher Education Compact held a conference on higher education and economic growth. Speakers included Michael Moskow, Richard Lester, Michael Luger, Sean Safford, Larry Isaak, Stefanie Lenway, Rod Shrader, Brian Fabes, Arthur Rothkopf, Randy Eberts, Gary Fethke, Victor…

  8. Following Michael Faraday's Footprints

    ERIC Educational Resources Information Center

    Galeano, Javier

    2011-01-01

    Last fall I had the good fortune of receiving financial support to shoot a documentary about Michael Faraday. I took the opportunity to learn more about this great experimentalist and to visit the highlights of places in his life. In this paper, I would like to share a list and description of some of the most remarkable places in London suitable…

  9. Our Hidden Prejudices, on Trial

    ERIC Educational Resources Information Center

    Glenn, David

    2008-01-01

    In October 2006, a New Hampshire police officer named Michael Briggs was shot to death in an alley. His accused killer, Michael Addison, has been charged with capital murder. It is the state's first death-penalty case in more than 30 years, and it is racially fraught: Addison is African-American, and Briggs was white. New Hampshire has a long list…

  10. X-Ray Pulse Selector With 2 ns Lock-in Phase Setting And Stability

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lindenau, B.; Raebiger, J.; Polachowski, S.

    2004-05-12

    Selector devices, which are based on magnetically suspended, high speed triangular shutter rotors, have been designed and built in cooperation with ESRF, APS, and recently Spring-8 for time resolved studies with isolated x-ray pulses at white beam lines. The x-ray pulse selection is accomplished by means of a beam channel along one of the edges of the triangular rotor, which opens once per revolution. Entrance and exit apertures of the channel can be designed wedge shaped for variable tuning of the channel height between 0.1 mm to 0.9 mm. At the 1 kHz maximum operation frequency of a 220 mmmore » diameter disk with 190 mm channel length, the practicable open times of the channel are demonstrated to range down to 200 ns. The selector drive electronics is directly coupled to the storage ring RF clock for rotational phase control. It allows for continuous selector operation in phase locked mode to the temporal pulse structure of the synchrotron at 2 ns RMS stability. The phase angle between the pulse transmission period and the synchrotron bunch sequence can be adjusted with similar precision for X-ray pulse selection according to the experimental needs. ID09, Michael Wulff ; BioCARS 14-BM, Reinhard Pahl; BL40-XU, Shin-ichi Adachi.« less

  11. High-frequency optical oscillation during the flare phase of the red dwarf EV Lac

    NASA Astrophysics Data System (ADS)

    Contadakis, M.; Avgoloupis, S.; Seiradakis, J.

    2006-01-01

    The observational support of the presence of high frequency low amplitude oscillations reported by Zhillyaev et al. 2000 and Contadakis et al. 2004, is highly demanding and will be done by the future observations and by carefully reanalysing the data from our files. In this paper we present the results of the analysis of the B-light curve for a flare of magnitude 1.01,which was observed on September,1993. Despite the low time resolution (sampling interval 12s) we were able to detect transient low amplitude oscillations with period ranging between 30s and 125s with a confidence level higher than 70%. This result is in favour of (or does not contradict) the suggested explanation i.e the evolution of a fast mode magneto-acoustic wave generated at the impulsive phase of the flare and travelling through the magnetic loop From: Michael E.Contadakis Address: kodadaki@vergina.eng.auth.gr Database: phy

  12. 14-qubit entanglement: creation and coherence

    NASA Astrophysics Data System (ADS)

    Barreiro, Julio

    2011-05-01

    We report the creation of multiparticle entangled states with up to 14 qubits. By investigating the coherence of up to 8 ions over time, we observe a decay proportional to the square of the number of qubits. The observed decay agrees with a theoretical model which assumes a system affected by correlated, Gaussian phase noise. This model holds for the majority of current experimental systems developed towards quantum computation and quantum metrology. We report the creation of multiparticle entangled states with up to 14 qubits. By investigating the coherence of up to 8 ions over time, we observe a decay proportional to the square of the number of qubits. The observed decay agrees with a theoretical model which assumes a system affected by correlated, Gaussian phase noise. This model holds for the majority of current experimental systems developed towards quantum computation and quantum metrology. Work done in collaboration with Thomas Monz, Philipp Schindler, Michael Chwalla, Daniel Nigg, William A. Coish, Maximilian Harlander, Wolfgang Haensel, Markus Hennrich, and Rainer Blatt.

  13. Production of Low-Freezing-Point Highly Branched Alkanes through Michael Addition.

    PubMed

    Jing, Yaxuan; Xia, Qineng; Liu, Xiaohui; Wang, Yanqin

    2017-12-22

    A new approach for the production of low-freezing-point, high-quality fuels from lignocellulose-derived molecules was developed with Michael addition as the key step. Among the investigated catalysts, CoCl 2 ⋅6 H 2 O was found most active for the Michael addition of 2,4-pentanedione with FA (single aldol adduct of furfural and acetone, 4-(2-furanyl)-3-butene-2-one). Over CoCl 2 ⋅6 H 2 O, a high carbon yield of C 13 oxygenates (about 75 %) can be achieved under mild conditions (353 K, 20 h). After hydrodeoxygenation, low-freezing-point (<223 K) branched alkanes with 13 carbons within jet fuel ranges were obtained over a Pd/NbOPO 4 catalyst. Furthermore, C 18,23 fuel precursors could be easily synthesized through Michael addition of 2,4-pentanedione with DFA (double-condensation product of furfural and acetone) under mild conditions and the molar ratio of C 18 /C 23 is dependent on the reaction conditions of Michael addition. After hydrodeoxygenation, high density (0.8415 g mL -1 ) and low-freezing-point (<223 K) branched alkanes with 18, 23 carbons within lubricant range were also obtained over a Pd/NbOPO 4 catalyst. These highly branched alkanes can be directly used as transportation fuels or additives. This work opens a new strategy for the synthesis of highly branched alkanes with low freezing point from renewable biomass. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  14. Friction in Command and Control: Sources of Conflict in Military Doctrine

    DTIC Science & Technology

    2011-06-01

    Colonel Michael W. Kometer (Date) ____________________________________ Dr. S . Michael Pavelec (Date...central belief s . This chapter will attempt to clarify these terms. Unity of Command Martin Van Creveld defines command ―as a function that has to...execution.17 Control The semantic demarcation between Air Force and Marine command and control doctrine s comes with the different approaches to

  15. Evaluating U.S. Military Engineering Efforts In East Africa

    DTIC Science & Technology

    2013-03-01

    Michael J. Neumann, Cathryn Quantic Thurston, Developing an Army Strategy for Building Partner Capacity for Stability Operations (Santa Monica, CA...Building Partnership Capacity, Master of Military Art and Science Thesis (Fort Leavenworth, KS: U.S. Army Command and General Staff College, June...Lynch, Michael J. Neumann, Cathryn Quantic Thurston, Developing an Army Strategy for Building Partner Capacity for Stability Operations, (Santa Monica

  16. Michael Griffin Discusses Exploration Architecture Study

    NASA Image and Video Library

    2005-09-18

    NASA Administrator Michael Griffin discusses the results of the agency's exploration architecture study on Monday, Sept. 19, 2005, at NASA Headquarters in Washington. The study made specific design recommendations for a vehicle to carry crews into space, a family of launch vehicles to take missions to the moon and beyond, and a "lunar mission architecture" for landing on the moon. Photo Credit: (NASA/Bill Ingalls)

  17. Recollections of Jack Michael and the Application of Skinner's Analysis of Verbal Behavior

    ERIC Educational Resources Information Center

    Sundberg, Mark L.

    2017-01-01

    Jack Michael offered a course on verbal behavior almost every year throughout his teaching career. Jack was also interested in the application of Skinner's work and in 1976 began to offer a graduate course at Western Michigan University titled Verbal Behavior Applications. Jack and his students pursued the application of Skinner's work on verbal…

  18. Schools as "Poetry-Friendly Places": Michael Rosen on Poetry in the Curriculum

    ERIC Educational Resources Information Center

    Xerri, Daniel

    2014-01-01

    This article explores the views of children's poet Michael Rosen in relation to poetry in education. It is based on an interview in which Rosen not only discusses the significance of encouraging young people to engage with poetry at school but also analyzes a number of threats to poetry's place in the English curriculum. This article identifies…

  19. Key Performance Indicators: From Promise to Payoff. The Productivity for Results Series No. 2

    ERIC Educational Resources Information Center

    Casserly, Michael; Eugene, Michael

    2014-01-01

    This paper draws upon the expertise of two leading educators, Michael Casserly, director of the Council of the Great City Schools, and Michael Eugene, chief operating officer of the Orange County Public Schools in Florida. They outline a set of key performance indicators that some urban districts use to benchmark the results of their operating…

  20. Expedition 19 Docks to ISS

    NASA Image and Video Library

    2009-03-27

    Michelle Barratt wishes her husband, NASA Astronaut Michael Barratt, a happy wedding anniversary via phone to the International Space Station from the Russian Mission Control Center, Korolev, Russia, Saturday, March 28, 2009. The Soyuz TMA-14 spacecraft docked to the International Space Station and delivered Expedition 19 Commander Gennady I. Padalka, Flight Engineer Michael R. Barratt and Spaceflight Participant Charles Simonyi. Photo Credit: (NASA/Bill Ingalls)

  1. Instructional Features for Training in Virtual Environments

    DTIC Science & Technology

    2006-07-01

    Technical Report 1184 Instructional Features for Training in Virtual Environments Michael J. Singer U. S. Army Research Institute Jason P. Kring...Report 1184 Instructional Features for Training in Virtual Environments Michael J. Singer U. S. Army Research Institute Jason P. Kring University of...provides in comparison to traditional, real world experience training programs (Hays & Singer , 1989; Swezey & Andrews, 2001). First, as with the

  2. A Response to Michael W. Apple's "Theory, Research, and the Critical Scholar/Activist"

    ERIC Educational Resources Information Center

    Leonardo, Zeus

    2010-01-01

    Michael Apple's prescient review of Anyon et al.'s "Theory and Educational Research" reminds the educational community of the importance of purpose. In his own work, he has been consistent in--actually, insistent on--emphasizing the struggle over political projects. This is not an issue concerning only the Left as the scapegoat for the disparaging…

  3. Jack Michael's Musings on the 60th Anniversary of Skinner's "Verbal Behavior"

    ERIC Educational Resources Information Center

    Esch, Barbara E.; Esch, John W.; Palmer, David C.

    2017-01-01

    When the B. F. Skinner Foundation reprinted Skinner's "Verbal Behavior" in 1992, Jack Michael wrote one of its two forewords, a detailed outline of the book's purpose and scope. On the 60th anniversary of the first publication (1957) of "Verbal Behavior", Jack reflects on the book's impact and its importance to the…

  4. Germania Quo Vadis?: Dynamics of Change in German Security Policy

    DTIC Science & Technology

    2007-06-01

    Keohane, Robert O., Michael Brecher and Frank Harveys, eds. Institutional Theory in international Relations. In: Millennial Reflections on International...Hegemony: Cooperation and Discord in the World Political Economy, (Princeton University Press, 1984), pp. 78-109; Robert O. Keohane, “ Institutional ... Theory in international Relations,” in Michael Brecher and Frank Harveys, eds., Millennial Reflections on International Studies (University of Michigan

  5. A rapid, one-pot, microwave-influenced synthesis of spiro-2,5-diketopiperazines via a cascade Ugi/6-exo-trig aza-Michael reaction.

    PubMed

    Santra, Soumava; Andreana, Peter R

    2011-04-01

    A rapid, cascade reaction process has been developed to access biologically validated spiro-2,5-diketopiperazines. The facile and environmentally benign method capitalizes on commercially available starting reagents for a sequential Ugi/6-exo-trig aza-Michael reaction, water as a solvent, and microwave irradiation without any extraneous additives.

  6. Preventive Health Care Utilization: A Study of Factors Influencing Military Personnel in Their Use of Three Preventive Health Care Factors

    DTIC Science & Technology

    1978-03-01

    0Michael Zubkoff and David Dunlop, " Consumer Behavior in Preventive Health Services," in Consumer Incentives for Health Care, ed. Selma J. Mushkin (New...78 Sorkin, Alan L. Health Economics. Lexington, Mass.: D.C. Heath, 1975. Zubkoff, Michael, and Dunlop, David. " Consumer Behavior in Preventive Health

  7. An Integral Part of the Frederick Community—Michael Dean | Poster

    Cancer.gov

    For more than 30 years, Michael Dean, Ph.D., has been an integral part of the NCI at Frederick community. In addition to studying several different aspects of genomics and cancer research, he has worked with the Werner H. Kirsten Student Intern Program and also volunteered his time with Mission of Mercy, a community-based organization providing free healthcare and free

  8. Too Many References, Just Cut a Few and It Will Be Perfect: APA vs. Chicago

    ERIC Educational Resources Information Center

    Matusov, Eugene

    2011-01-01

    The purpose of the author's rebuttal is to provide a sociocultural critique of Wolff-Michael Roth and Michael Cole's arguments and of the current "Mind, Culture, and Activity" ("MCA") policy regarding referencing. In sum, Roth and Cole write that some unnamed "MCA" authors (and some scholars in general) abuse the reference practice by…

  9. CAS, Interdiction, and Attack Helicopters

    DTIC Science & Technology

    2005-06-01

    E.J. Degen, and David Tohn, On Point: The United States Army in Operation Iraqi Freedom, (Fort Leavenworth, KA : Combat Studies Institute Press, 2004...Grau and Michael W. Gress, trans. and eds. The Soviet- Afghan War: How a Superpower Fought and Lost, (Lawrence, KA : University Press of Kansas, 2002...149 Grinalds, 73. 150 Michael O’Hanlon and Adriana Lins de Albuquerque, Iraq Index: Tracking Variables

  10. Effective Integration of Technology and Instruction. Q&A with Michael Jay. REL Mid-Atlantic Educator Effectiveness Webinar Series

    ERIC Educational Resources Information Center

    Regional Educational Laboratory Mid-Atlantic, 2015

    2015-01-01

    In this webinar, long-time educator and developer of education technology Michael Jay discussed the importance of using technology to support learning and gave examples of how teachers can integrate technology into their instruction based on the Common Core State Standards and the Next Generation Science Standards. The PowerPoint presentation and…

  11. The Data on Children's Media Use: An Interview with Michael Robb

    ERIC Educational Resources Information Center

    Heller, Rafael

    2018-01-01

    Since 2003, nonprofit organization Common Sense Media has studied the ways in which kids are growing up in the digital age. In this interview, research director Michael Robb shares recent findings about the media habits of young children, tweens, and teens. While the news coverage of these issues tends to be hyperbolic and alarming, Robb explains,…

  12. Unification of South Asia

    DTIC Science & Technology

    1994-06-03

    34Religious vs regional determinism: India , Pakistan , and Bangladesh as inheritors of empire," in Shared Space: Divided Space. ed. Michael Chisholm and David M...Chapman, Reliaion vs . reaional determinism: India . Pakistan . and Banaladesh as inheritors ofempire, in Shared Space: Divided Space, ed. Michael Chisholm...and David Smith, (London: Unwin Hyman, 1990), 107. 47. Graham Chapman, Reliaion vs . recional determinism: India . Pakistan . and Banaladesh as

  13. Fiscal Law Course Deskbook (36th)

    DTIC Science & Technology

    1993-05-01

    CONTRACT LAW DIVISION THE JUDGE ADVOCATE GENERAL’S SCHOOL UNITED STATES ARMY CHARLOTTESVILLE, VIRGINIA JA 506...MAY 93 93-13173 CONTRIBUTORS I LTC John T. Jones, Jr. Chief, Contract Law Division LTC Harry L. Dorsey Senior Instructor, Contract Law Division MAJ...Michael A. Killham Instructor, Contract Law Division MAJ Bobby D. Melvin Instructor, Contract Law Division MAJ Michael K. Cameron Instructor, Contract

  14. 56th Yearbook of the National Reading Conference (Los Angeles, California, November 29-December 2, 2006)

    ERIC Educational Resources Information Center

    Rowe, Deborah Wells, Ed.; Jimenez, Robert T., Ed.; Compton, Donald L., Ed.; Dickinson, David K., Ed.; Kim, Youb, Ed.; Leander, Kevin M., Ed.; Risko, Victoria J., Ed.

    2007-01-01

    This publication offers the 56th Yearbook of the National Reading Conference (NRC). This Yearbook begins with a preface and presents profiles of three awardees, Michael C. McKenna, Douglas K. Hartman, and Michael Kamil. Included in this Yearbook are the following papers: (1) What's It All About? Literacy Research and Civic Responsibility (Victoria…

  15. Shaping the Global Civil Society: An Interview with Michael Peters

    ERIC Educational Resources Information Center

    Heraud, Richard; Tesar, Marek

    2017-01-01

    Professor Michael A. Peters has worked in an era of transformation that has taken him from a labour-intensive paper-based form of production to the computerised reproduction of thought, and the current shift in the publishing landscape from a reader-subscription to an author-pays model. Most of what he has learned in publishing and editing he has…

  16. Software Requirements Engineering Methodology (Development)

    DTIC Science & Technology

    1979-06-01

    Higher Order Software [20]; and the Michael Jackson Design Methodology [21]. Although structured programming constructs have proven to be more useful...reviewed here. Similarly, the manual techniques for software design (e.g., HIPO Diagrams, Nassi-Schneidermann charts, Top-Down Design, the Michael ... Jackson Design Methodology, Yourdon’s Structured Design) are not addressed. 6.1.3 Research Programs There are a number of research programs underway

  17. Michael Griffin Senate Confirmation Hearing

    NASA Image and Video Library

    2005-04-12

    Dr. Michael Griffin, right, talks with his wife Rebecca Griffin prior to testifying at his confirmation hearing before the U.S. Senate Commerce Committee, Tuesday, April 12, 2005, at the Russell Senate Office Building in Washington. If confirmed, Griffin, who currently heads the space department at the Johns Hopkins University Applied Physics Laboratory will become NASA's 11th administrator. Photo Credit (NASA/Renee Bouchard)

  18. Chiral-catalyst-based convergent synthesis of HIV protease inhibitor GRL-06579A.

    PubMed

    Mihara, Hisashi; Sohtome, Yoshihiro; Matsunaga, Shigeki; Shibasaki, Masakatsu

    2008-02-01

    Catalytic asymmetric synthesis of GRL-06579A (1), an HIV-1 protease inhibitor effective against multi-protease-inhibitor-resistant viruses, is described. A convergent strategy that utilizes heterobimetallic multifunctional catalysts developed in our group is a key feature of the synthesis. The chirality of the bicyclic tetrahydrofuran unit of 1 was introduced through Al-Li-bis(binaphthoxide) (ALB) catalyst-controlled Michael addition of dimethyl malonate to racemic 4-O-protected cyclopentenone. ALB afforded not only the trans adduct with up to 96% ee from a matched substrate through kinetic resolution, but also the cis adduct with 99% ee through a catalyst-controlled Michael addition to a mismatched substrate. The Michael addition to produce the unusual cis adduct is described in detail. The framework of the bicyclic tetrahydrofuran was constructed by an intramolecular oxy-Michael reaction. The amino alcohol unit was constructed by an La-Li3-tris(binaphthoxide) (LLB)-catalyzed diastereoselective nitroaldol reaction of N-Boc aldehyde (Boc = tert-butoxycarbonyl) derived from L-phenylalanine. LLB promoted the nitroaldol reaction without racemization of the chiral aldehyde to give the nitroaldol adduct in 85% yield and with 93:7 diastereoselectivity and over 99% ee.

  19. KENNEDY SPACE CENTER, FLA. -- Sandra Anderson, wife of STS-107 Payload Commander Michael Anderson, visits a new residence hall at the Florida Institute of Technology (FIT) in Melbourne, Fla., named for her late husband. Family members of the STS-107 astronauts, other dignitaries, members of the university community and the public gathered for a dedication ceremony for the Columbia Village at FIT. Each of the seven new residence halls in the complex is named for one of the STS-107 astronauts who perished during the Columbia accident -- Rick Husband, Willie McCool, Laurel Clark, Michael Anderson, David Brown, Kalpana Chawla, and Ilan Ramon.

    NASA Image and Video Library

    2003-10-28

    KENNEDY SPACE CENTER, FLA. -- Sandra Anderson, wife of STS-107 Payload Commander Michael Anderson, visits a new residence hall at the Florida Institute of Technology (FIT) in Melbourne, Fla., named for her late husband. Family members of the STS-107 astronauts, other dignitaries, members of the university community and the public gathered for a dedication ceremony for the Columbia Village at FIT. Each of the seven new residence halls in the complex is named for one of the STS-107 astronauts who perished during the Columbia accident -- Rick Husband, Willie McCool, Laurel Clark, Michael Anderson, David Brown, Kalpana Chawla, and Ilan Ramon.

  20. Theoretical study on the reaction mechanisms of Michael chirality addition between propionaldehyde and nitroalkene catalyzed by an enantioselective catalyst.

    PubMed

    Zhou, Xinming; Li, Ling; Sun, Xuejun; Wang, Yajun; Du, Dongmei; Fu, Hui

    2018-06-01

    The asymmetric Michael addition between propionaldehyde and nitroalkene catalyzed by 8-(ethoxycarbonyl)-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indole-2-carboxylic acid has obtained relatively high yields and excellent enantioselectivities at room temperature. In this study, the molecular structures and optical activity of the most stable conformation I are optimized at B3LYP/6-311++ G(d,p) level. We find that levorotatory conformation I catalyzing the same Michael addition can produce laevo-product A and dextrorotatory conformation I' can obtain the dextral-product A'. These results have guiding significance for further studying on the new chemzymes and the mechanism of the obtained different chiral products. © 2018 Wiley Periodicals, Inc.

  1. Michael Faraday vs. the Spiritualists

    NASA Astrophysics Data System (ADS)

    Hirshfeld, Alan

    2006-12-01

    In the 1850s, renowned physicist Michael Faraday launched a public campaign against pseudoscience and spiritualism, which were rampant in England at the time. Faraday objected especially to claims that electrical or magnetic forces were responsible for paranormal phenomena, such as table-spinning and communication with the dead. Using scientific methods, Faraday unmasked the deceptions of spiritualists, clairvoyants and mediums and also laid bare the credulity of a public ill-educated in science. Despite his efforts, Victorian society's fascination with the paranormal swelled. Faraday's debacle anticipates current controversies about public science education and the interface between science and religion. This episode is one of many described in the new biography, The Electric Life of Michael Faraday (Walker & Co.), which chronicles Faraday's discoveries and his unlikely rise from poverty to the pinnacle of the English science establishment.

  2. Pyrrolidinyl-camphor derivatives as a new class of organocatalyst for direct asymmetric Michael addition of aldehydes and ketones to beta-nitroalkenes.

    PubMed

    Ting, Ying-Fang; Chang, Chihliang; Reddy, Raju Jannapu; Magar, Dhananjay R; Chen, Kwunmin

    2010-06-18

    Practical and convenient synthetic routes have been developed for the synthesis of a new class of pyrrolidinyl-camphor derivatives (7 a-h). These novel compounds were screened as catalysts for the direct Michael addition of symmetrical alpha,alpha-disubstituted aldehydes to beta-nitroalkenes. When this asymmetric transformation was catalyzed by organocatalyst 7 f, the desired Michael adducts were obtained in high chemical yields, with high to excellent stereoselectivities (up to 98:2 diastereomeric ratio (d.r.) and 99 % enantiomeric excess (ee)). The scope of the catalytic system was expanded to encompass various aldehydes and ketones as the donor sources. The synthetic application was demonstrated by the synthesis of a tetrasubstituted-cyclohexane derivative from (S)-citronellal, with high stereoselectivity.

  3. ER-2 #809 and DC-8 in Arena Arctica hangar in Kiruna, Sweden prior to the SAGE III Ozone Loss and Validation Experiment (SOLVE)

    NASA Image and Video Library

    2000-01-23

    NASA ER-2 # 809 and its DC-8 shown in Arena Arctica before the SAGE III Ozone Loss and Validation Experiment (SOLVE). The two airborne science platforms were based north of the Arctic Circle in Kiruna, Sweden, during the winter of 2000 to study ozone depletion as part of SOLVE. A large hangar built especially for research, "Arena Arctica" housed the instrumented aircraft and the scientists. Scientists have observed unusually low levels of ozone over the Arctic during recent winters, raising concerns that ozone depletion there could become more widespread as in the Antarctic ozone hole. The NASA-sponsored international mission took place between November 1999 and March 2000 and was divided into three phases. The DC-8 was involved in all three phases returning to Dryden between each phase. The ER-2 flew sample collection flights between January and March, remaining in Sweden from Jan. 9 through March 16. "The collaborative campaign will provide an immense new body of information about the Arctic stratosphere," said program scientist Dr. Michael Kurylo, NASA Headquarters. "Our understanding of the Earth's ozone will be greatly enhanced by this research."

  4. Snakes on a plane: modeling flexible active nematics

    NASA Astrophysics Data System (ADS)

    Selinger, Robin

    Active soft matter systems of self-propelled rod-shaped particles exhibit ordered phases and collective behavior that are remarkably different from their passive analogs. In nature, many self-propelled rod-shaped particles, such as gliding bacteria and kinesin-driven microtubules, are flexible and can bend. We model these ``living liquid crystals'' to explore their phase behavior, dynamics, and pattern formation. We model particles as short polymers via molecular dynamics with a Langevin thermostat and various types of activity, substrate, and environments. For self-propelled polar particles gliding on a solid substrate, we map out the phase diagram as a function of particle density and flexibility. We compare simulated defect structures to those observed in colonies of gliding myxobacteria; compare spooling behavior to that observed in microtubule gliding assays; and analyze emergence of nematic and polar order. Next we explore pattern formation of self-propelled polar particles under flexible encapsulation, and on substrates with non-uniform Gaussian curvature. Lastly, we impose an activity mechanism that mimics extensile shear, study flexible particles both on solid substrates and coupled to a lipid membrane, and discuss comparisons to relevant experiments. Work performed in collaboration with Michael Varga (Kent State) and Luca Giomi (Universiteit Leiden.) Work supported by NSF DMR-1409658.

  5. STS-76 Flight Day 7

    NASA Technical Reports Server (NTRS)

    1996-01-01

    On this seventh day of the STS-76 mission, the flight crew, Cmdr. Kevin P. Chilton, Pilot Richard A Searfoss, and Mission Specialists Linda M. Godwin, Michael R. Clifford, and Ronald M. Sega are shown bidding the Mir crew and Shannon W. Lucid an emotional farewell, Chilton calling it 'a bittersweet moment.' The Atlantis and Mir commanders, Chilton and Onufrienko, along with spacewalkers Godwin and Clifford took time out to talk with CBS' 'Up to the Minute.' The space flyers discussed the success of their joint mission and the 6-hour spacewalk. The astronauts and cosmonauts exchanged handshakes and hugs in the Mir core module, and then praised both mission control centers, Houston and Kaliningrad for their support throughout the joint phase of the mission.

  6. Mission commander James Wetherbee on the forward flight deck

    NASA Image and Video Library

    1995-02-03

    STS063-06-027 (3-11 Feb 1995) --- Seated at the commander's station on the Space Shuttle Discovery's flight deck, astronaut James D. Wetherbee, commander, was photographed by a crew mate during early phases of the STS-63 mission. A great deal of time was spent during the first few days of the mission to check a leaky thruster, which could have had a negative influence on rendezvous operations with Russia's Mir Space Station. As it turned out, all the related problems were solved and the two spacecraft succeded in achieving close proximity operations. Others onboard the Discovery were astronauts Eileen M. Collins, pilot; Bernard A. Harris Jr., payload commander; and mission specialists C. Michael Foale, Janice E. Voss, and Russian cosmonaut Vladimir G. Titov.

  7. Optimal width of quasicrystalline slabs of dielectric cylinders to microwave radiation transmission contrast

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Andueza, Ángel; Sevilla, Joaquín; Smart Cities Institute, Universidad Pública de Navarra, 31006 Pamplona

    2016-08-28

    Light confinement induced by resonant states in aperiodic photonic structures is interesting for many applications. A particular case of these resonances can be found in 2D quasicrystalline arrangements of dielectric cylinders. These systems present a rather isotropic band gap as well as isolated in-gap photonic states (as a result of spatially localized resonances). These states are built by high symmetry polygonal clusters that can be regarded as photonic molecules. In this paper, we study the transmission properties of a slab of glass cylinders arranged in approximants of the decagonal quasicrystalline structure. In particular, we investigate the influence of the slabmore » width in the transmission contrast between the states and the gap. The study is both experimental and numerical in the microwave regime. We find that the best transmission contrast is found for a width of around three times the radiation wavelength. The transmission in the band gap region is mediated by the resonances of the photonic molecules. If the samples are thin enough, they become transparent except around a resonance of the photonic molecule which reflects the incoming light.« less

  8. Jack Michael's Appointments at the University of Houston and Arizona State University: Reflections from a Former Student

    ERIC Educational Resources Information Center

    Mabry, John H.

    2016-01-01

    Jack Michael was an early enthusiast for what is now called applied behavior analysis. His many seminal contributions were through early publications in applied behavior analysis and the work of the students he trained (e.g., T. Ayllon, M. M. Wolf). His close mentorship of students earned him acclaim as a teacher along with his many theoretical…

  9. Without the Light of Evolution: A Case Study of Resistance and Avoidance in Learning to Teach High School Biology

    ERIC Educational Resources Information Center

    Larkin, Douglas B.; Perry-Ryder, Gail M.

    2015-01-01

    We present the case of Michael, a prospective high school biology teacher, to explore the implications of teacher resistance and avoidance to the topic of evolution. This case is drawn from a year-long qualitative research study that examined Michael's process of learning to teach high school biology and describes how his avoidance of evolution in…

  10. The Effects of DHEA on Resilience to PTSD

    DTIC Science & Technology

    2011-04-01

    Resilience to PTSD Authors Cassandra M. Ellington Scott J. Wright Lolita M. Burrell Michael D. Matthews United States Military Academy...to PTSD 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Cassandra Ellington; Scott Wright; Lolita Burrell; Michael...Chilcoat, H. D., Kessler, R. C., Peterson, E. L., & Lucia, V. C. (1999). Vulnerability to assaultive violence: Further specification of the sex

  11. Minding the Factors of Public Support: How Lessons From Panama Could Prevent Future Iraqs

    DTIC Science & Technology

    2017-06-01

    NAVAL POSTGRADUATE SCHOOL MONTEREY, CALIFORNIA THESIS Approved for public release. Distribution is unlimited. MINDING THE FACTORS...OF PUBLIC SUPPORT: HOW LESSONS FROM PANAMA COULD PREVENT FUTURE IRAQS by Michael S. Handlan Michael D. Salazar June 2017 Thesis... Public reporting burden for this collection of information is estimated to average 1 hour per response, including the time for reviewing

  12. Benefits of a Hospital Two-Bin Kanban System

    DTIC Science & Technology

    2014-09-01

    Reader : Michael Dixon THIS PAGE INTENTIONALLY LEFT BLANK i REPORT DOCUMENTATION PAGE Form Approved OMB No. 0704–0188 Public reporting burden for...Approved by: Nedialko Dimitrov Thesis Advisor Rachel Silvestrini Co-Advisor Michael Dixon Second Reader Robert F. Dell Chair...stocks split between primary (in front) and secondary bins (directly behind). RFID tags are placed on the front of each bin. Photos taken at WRNMMC

  13. Using a Counterfactual Process to Identify the Applicability of Emerging Technology

    DTIC Science & Technology

    2014-09-01

    conditions that must exist for the antecedent to happen.129 Crafting a 126 Michael W. Morris and...opportunities of interrupting the sequence of events. For example, if the bombers were identified on Monday then the events that unfold on Tuesday ...www.telegraph.co.uk/news/worldnews/northamerica/usa/10006491/Boston- marathon-bombings-Dzhokhar-Tsarnaev-pictured-behind-eight-year-old- victim.html Morris , Michael

  14. Systems Fragility: The Sociology of Chaos

    DTIC Science & Technology

    2015-03-01

    Science (New York, N.Y.) 302, no. 5652 (2004): 1912, doi:10.1126/science.1090847. 70 Barry Wellman, and Scot Wortley, “Different Strokes from...Michael Dombeck, Jack Williams, and Christopher Wood , “Wildfire Policy and Public Lands: Integrating Scientific Understanding with Social Concerns...bitstream/10092/2809/ 1/12593870_ResOrgs_IFED_dec04_EDSM.pdf Dombeck, Michael, Jack Williams, and Christopher Wood . “Wildfire Policy and Public

  15. Michael Faraday, media man.

    PubMed

    Fara, Patricia

    2006-03-01

    Michael Faraday was an enthusiastic portrait collector, and he welcomed the invention of photography not only as a possible means of recording observations accurately, but also as a method for advertising science and its practitioners. This article (which is part of the Science in the Industrial Revolution series) shows that like many eminent scientists, Faraday took advantage of the burgeoning Victorian media industry by posing in various roles.

  16. Michael Novak's "Business as a Calling" as a Vehicle for Addressing Ethical and Policy Concerns in a Business Law Course

    ERIC Educational Resources Information Center

    Murphy, Tonia Hap

    2008-01-01

    This article describes the author's experience of incorporating Michael Novak's "Business as a Calling: Work and the Examined Life" into a Business Law course. The author views it as a positive addition to the course, one that may be of interest to her colleagues at other institutions. Accordingly, after an overview of Novak's analysis in…

  17. Guam: U.S. Defense Deployments

    DTIC Science & Technology

    2013-11-15

    Guam. Deputy Assistant Secretary of Defense for Asian and Pacific Security Affairs Michael Schiffer added later that there would need to be parallel...maintain unit cohesion and operational readiness. In answer to Mr. Forbes’s question of whether the Air-Sea Battle Concept was ready, Schiffer ...officials have tied the buildup to North Korea’s threat. Deputy Assistant Secretary of Defense for East Asia Michael Schiffer testified to Congress

  18. A Symposium on the Relevance of Michael Polanyi's Insights to a Reformulated Understanding of Science, Technology, and Society

    ERIC Educational Resources Information Center

    Mead, Walter B.

    2011-01-01

    This is intended as an introductory statement to the explorations undertaken in the essays that follow. The authors of these essays attempt to introduce the reader to some of the insights of Michael Polanyi and their implications for the reader who wishes to come to a greater understanding of modern technological society, which--for better or…

  19. Molecular Nitrogen Fluorescence Lidar for Remote Sensing of the Auroral Ionosphere

    DTIC Science & Technology

    1994-02-24

    AD-A280 716 PL-TR-94-2044 MOLECULAR NITROGEN FLUORESCENCE LIDAR FOR REMOTE SENSING OF THE AURORAL IONOSPHERE Richard Garner Michael Burka...6. AUTHOR(S) Richard Garner Contract F19628-92-C-0160 Michael Burka 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) 8. PERFORMING ORGANIZATION...by Richard Dickmuaz of the HIPAS observatory and by Ralph Wuerker of UCLA PPL. 29 le

  20. How "The Right" Continues to "Do Wrong" by Our Young People: Contemporary Reflections on Michael Apple's Analysis of the "Rightist Turn" in Education

    ERIC Educational Resources Information Center

    McGregor, Glenda

    2018-01-01

    Michael Apple's 2005 article, "Doing Things the 'Right' Way: Legitimating Educational Inequalities in Conservative Times", is a seminal piece of writing that highlights some of his core concerns with the effects of neo-liberal and neo-conservative ideologies on education. Since its publication, this article has incited much debate about…

  1. RAND Project Air Force Annual Report 2008

    DTIC Science & Technology

    2008-01-01

    Systems: Past Lessons and Future Recommendations, by Obaid Younossi, Mark A. Lorell, Kevin Brancato, Cynthia R. Cook, Mel Eisman, Bernard Fox, John C...Competency Development: Experience from Prince Sultan Air Base and Eskan Village in Saudi Arabia, by Laura Werber Castaneda, Lawrence M. Hanser, and...Proposal, by Michael R. Thirtle, Michael Boito, Ian P. Cook, Bernard Fox, Phyllis Gilmore, Michelle Grace, Jeff Hagen, Thomas Hamilton

  2. What's in a Name? That Which We Call a Crisis? A Commentary on Michael Young's Article "Overcoming the Crisis in Curriculum Theory"

    ERIC Educational Resources Information Center

    Lundgren, Ulf P.

    2015-01-01

    Michael Young's article "Overcoming the crisis in curriculum theory: a knowledge-based approach" ("JCS, 45", 2) is discussed from the starting point that the claimed crisis is constructed from a decisive solution, that is the solution determines what is a crisis. But curriculum research and curriculum theory are in need of…

  3. What I Think I May Have Learned--Reflections on 50 Years of Teaching: An Interview with Michael Wertheimer

    ERIC Educational Resources Information Center

    Michael, Kurt D.

    2006-01-01

    Kurt Michael is an associate professor in the Department of Psychology at Appalachian State University (ASU) where he teaches history and systems of psychology, abnormal psychology, child psychopathology, and interventions for children and adolescents. He received his BA (cum laude) from the University of Colorado at Boulder and his MS and PhD in…

  4. Coping with Iran: Confrontation, Containment, or Engagement

    DTIC Science & Technology

    2007-01-01

    participating via videoconference from the UN in New York) Questions: Michael Hirsh (senior editor, Newsweek) David Ignatius (national security columnist , The...national security columnist , The Washington Post) HOW THE U.S. GOVERNMENT VIEWS IRAN R. Nicholas Burns The foundations of national security policy are...Michael Hirsh Senior Editor Newsweek David Ignatius National Security Columnist The Washington Post 2:15 P.M. -- Panel 3: What to Do

  5. Expedition 18 Door Signing

    NASA Image and Video Library

    2008-10-11

    Expedition 18 Commander Michael Fincke signs the door of a hotel room at the Cosmonaut Hotel prior to departing for the launch aboard a Soyuz TMA-13 spacecraft, Sunday, Oct. 12, 2008, in Baikonur, Kazakhstan. The Soyuz TMA-13 spacecraft launched from the Baikonur Cosmodrome in Kazakhstan carrying Expedition 18 Commander Michael Fincke, Flight Engineer Yuri V. Lonchakov and American spaceflight participant Richard Garriott. Photo Credit: (NASA/Bill Ingalls)

  6. Michael Griffin Senate Confirmation Hearing

    NASA Image and Video Library

    2005-04-12

    U.S. Senator Barbara Mikulski, D-Md., left, talks with Michael Griffin as Senator Kay Bailey Hutchison, R-Tx., and Griffin's wife Rebecca look on prior to his testimony, Tuesday, April 12, 2005, at the Russell Senate Office Building in Washington. If confirmed, Griffin, who currently heads the space department at the Johns Hopkins University Applied Physics Laboratory will become NASA's 11th administrator. Photo Credit: (NASA/Renee Bouchard)

  7. Counterinsurgency in West Africa: Non Lethal Activities

    DTIC Science & Technology

    2009-06-01

    Michael S. Lewis Beck, Alan Bryman , Tim Futing Liao, The SAGE Encyclopedia of Social Science Research Methods , SAGE, 2004, California, USA.p.894. 11...Publishing, 1966. Michael S. Lewis Beck, Alan Bryman , Tim Futing Liao, The SAGE Encyclopedia of Social Science Research Methods , SAGE, 2004...conduct the research . Research Design The methodology that will be used in this thesis is a qualitative method using case studies. Qualitative research

  8. Binaural Processing of Multiple Sound Sources

    DTIC Science & Technology

    2016-08-18

    Sound Source Localization Identification, and Sound Source Localization When Listeners Move. The CI research was also supported by an NIH grant...8217Cochlear Implant Performance in Realistic Listening Environments,’ Dr. Michael Dorman, Principal Investigator, Dr. William Yost unpaid advisor. The other... Listeners Move. The CI research was also supported by an NIH grant (“Cochlear Implant Performance in Realistic Listening Environments,” Dr. Michael Dorman

  9. Sacred Values, Strategic Communication, and Military Operations in Afghanistan

    DTIC Science & Technology

    2010-02-17

    remembrance afterward is nothing less than a people‟s mass. War is the liturgy of identity.” Michael Vlahos 20 Combatant commanders (COCOMs) require...development. Identify Formation: Michael Vlahos ―…maintains that the process of globalization ushered into human consciousness a crisis of human change...provide contexts for the clash of political will. Conflict provides stories, symbols, and rituals that create narratives and form identity. Vlahos

  10. Dome: Distributed Object Migration Environment

    DTIC Science & Technology

    1994-05-01

    Best Available Copy AD-A281 134 Computer Science Dome: Distributed object migration environment Adam Beguelin Erik Seligman Michael Starkey May 1994...Beguelin Erik Seligman Michael Starkey May 1994 CMU-CS-94-153 School of Computer Science Carnegie Mellon University Pittsburgh, PA 15213 Abstract Dome... Linda [4], Isis [2], and Express [6] allow a pro- grammer to treat a heterogeneous network of computers as a parallel machine. These tools allow the

  11. Design and Control of a Closed-Loop Brushless Torque Activator

    DTIC Science & Technology

    1990-05-01

    AD-A270 760 Technical Report 1244 Design and Control of a Closed-Loop Brushless Torque Activator Michael Dean Levi MIT Artificial Intelligence... Brushless N00014-86-K-0685 Torque Actuator 6. AUTHOR(S) Michael Dean Levin 7. PERFORMING ORGANIZATION NAME(S) AND ADORESS(ES) B. PERFORMING...200 words) This’report explores the design and control issues associated with a brushless actuator capable of achieving extremely high torque

  12. Using Crowdsourced Geospatial Data to Aid in Nuclear Proliferation Monitoring

    DTIC Science & Technology

    2016-12-01

    M. Stephens, and Ronald D. Bonnell, “DAI for Document Retrieval: The MINDS Project,” in Distributed Artificial Intelligence , ed. Michael N. Huhns...Ronald D. Bonnell. “DAI for Document Retrieval: The MINDS Project,” In Distributed Artificial Intelligence , edited by Michael N. Huhns, 249–283...was for the director of National Intelligence to explore ways that crowdsourced geospatial imagery technologies could aid existing governmental

  13. MX Hierarchical Networking System.

    DTIC Science & Technology

    1982-02-01

    criteria considered in this report are defined as follows: 1. Single Network Limitation. Will the scheme allow the maximum size network anticipated to be...AD-AI16 758 CONSTRUCTION ENGINEERING RESEARCH LAB (ARMY) CHAMPAIGN IL F/G 5/2 MX HIERARCHICAL NETWORKING SYSTEM.(U) FEB 82 M O-CONNOR, L M SOLISH, L...laboratory__ _ _ _ _ _ _ _ _ _ _ _ MX HIERARCHICAL NETWORKING SYSTEM by Michael O’Connor L. Michael Golish Lee Boyer IsI Approved for public

  14. Quantitative Methods for Long-Range Environmental Forecasting. Long-Wave European Projections. Volume 2. Technical Volume

    DTIC Science & Technology

    1974-03-01

    approaches to specific problems within the foreign affairs community ( e . g. , within DoD). The lag resulted from a variety of factors, in...ICATIOH / Prepared by: Herman M. Weil Airon Greenberg Larry German Douglas Hartwick Michael R. Leavitt Sponsored by: Defense Advanced...I Dr. G. Robert Franco, Project Director Dr. Herman M. Weil Mr. Aaron Greenberg Mr. Larry German Mr. Douglas Hartwick Dr. Michael

  15. Message in a Battle: An Analysis of Presidential Communication Since 9/11

    DTIC Science & Technology

    2013-03-01

    Rumsfeld as quoted in Michael Jacobson, “ Learning Counter-Narrative Lessons from Cases of Terrorist Dropouts,” Countering Violent Extremist Narratives...October 29. 2012, http://www.cfr.org/terrorism/improving-us-public-diplomacy-campaign-war-against-terrorism/p4215. 21 Michael Jacobson, “ Learning Counter...States Government as potential new perspectives are introduced through which lessons can be learned regarding the construction and expression of a

  16. Using Our Voices, Losing Our Bodies: Michael Brown, Trayvon Martin, and the Spirit Murders of Black Male Professors in the Academy

    ERIC Educational Resources Information Center

    Johnson, Lamar; Bryan, Nathaniel

    2017-01-01

    The recent deaths of Michael Brown, Trayvon Martin, and other Black males have generated new civil rights urgencies in Black communities and spirited academic discourses in higher education regarding the educational and social plight of Black males in America. Connecting the deaths of Black males to our lived experiences in the academy, we use a…

  17. Risk of Using Past to Predict Future: A Case Study of Jamming RCIEDs

    DTIC Science & Technology

    2009-06-01

    Herrera THIS PAGE INTENTIONALLY LEFT BLANK i REPORT DOCUMENTATION PAGE Form Approved OMB No. 0704-0188 Public reporting burden for this...Approved by: Kyle Y. Lin Thesis Advisor Michael A. Herrera Second Reader Robert F. Dell Chairman, Department of Operations...and continue forward. Thank you, CDR Michael Herrera , for your constant positive support and never allowing for me to lose sight of the goal. Dr

  18. Organocatalytic Enantioselective Michael/Cyclization Domino Reaction between 3-Amideoxindoles and α,β-Unsaturated Aldehydes: One-Pot Preparation of Chiral Spirocyclic Oxindole-γ-lactams.

    PubMed

    Yang, Peng; Wang, Xiao; Chen, Feng; Zhang, Zheng-Bing; Chen, Chao; Peng, Lin; Wang, Li-Xin

    2017-04-07

    The first organocatalytic enantioselective Michael/cyclization domino reaction between 3-amideoxindoles and α,β-unsaturated aldehydes is described. After sequential oxidation with pyridinium chlorochromate, a direct and one-pot preparation of highly sterically hindered spirocyclic oxindole-γ-lactams was achieved in 51-81% yields with 75-97% ee and ≤80/20 dr.

  19. Time for a Change? Composite Field Artillery Battalions

    DTIC Science & Technology

    2014-06-13

    Michael F. Morris , uses the battle as a case study on future employment of Marine Forces. Significantly, Major Morris ’ analysis reveals the importance...that the South African artillery played in the fighting. Calling it, “the star of the campaign.”6 Major Morris also believes that the Marine Corps...Force 1991-2005 relates the history behind the modular brigade. In “The 6Michael F. Morris

  20. A Philosophy of Jewish Education in Question Marks: A Possible Reading of Michael Rosenak's Last Speech

    ERIC Educational Resources Information Center

    Rosenak, Avinoam

    2014-01-01

    Writing this article presents me with an opportunity to look closely at the last speech that my father and mentor, Professor Michael (Mike) Rosenak z"l gave before his passing in 2013. I will write about this speech from a perspective that is based on my intimate familiarity with the questions that concerned him throughout his life. I will…

  1. ARC-2008-ACD08-0186-005

    NASA Image and Video Library

    2008-07-30

    NASA Ames Robotics Academy Interns at the Lunar Science Institute (LSI) building 17 Interns: David Black, Michael Zwach, Guy Chriqui, Mark Mordarski Jr., Katy Levinson, Daniela Buchman, Scott Strutner, Patrick Crownover, Neil Bhateja, Michael Buchman, John Mueller, Michelle Grau, Ben Silver, Jacques Dolan, Alex Golec Windell Jones, Colin Wilson, Joe DeBlasio, Nick Hayes, Jordan Olive, William Shaw, Ames Education Dept., Mark Leon, Ames Robotics, Josh Weiner, jack Biesiadecki, Andrew Pilloud

  2. Mission Specialist Michael Lopez-Alegria changes out film in camera

    NASA Image and Video Library

    1995-11-05

    STS073-335-009 (20 October-5 November 1995) --- Astronaut Michael E. Lopez-Alegria, STS-73 mission specialist, changes the film in a 35mm camera on the flight deck of the Earth-orbiting Space Shuttle Columbia. Alegria joined four other NASA astronauts and two guest researchers for almost 16-days of Earth-orbit research in support of the U.S. Microgravity Laboratory (USML-2) mission.

  3. Forty Years of "Pastoral Care": An Appraisal of Michael Marland's Seminal Book and Its Significance for Pastoral Care in Schools

    ERIC Educational Resources Information Center

    Best, Ron

    2014-01-01

    Michael Marland's seminal book: "Pastoral Care" was published 40 years ago this year. The thesis of the book--that pastoral care is the central task of the school, and must be planned and institutionalized through pastoral roles and structures--is explored against the background of the social, cultural and educational developments…

  4. An Integral Part of the Frederick Community—Michael Dean | Poster

    Cancer.gov

    For more than 30 years, Michael Dean, Ph.D., has been an integral part of the NCI at Frederick community. In addition to studying several different aspects of genomics and cancer research, he has worked with the Werner H. Kirsten Student Intern Program and also volunteered his time with Mission of Mercy, a community-based organization providing free healthcare and free prescription medications to the uninsured and under-insured.

  5. Highlighting High Performance: Michael E. Capuano Early Childhood Center; Somerville, Massachusetts

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    2006-03-01

    This brochure describes the key high-performance building features of the Michael E. Capuano Early Childhood Center. The brochure was paid for by the Massachusetts Technology Collaborative as part of their Green Schools Initiative. High-performance features described are daylighting and energy-efficient lighting, indoor air quality, solar and wind energy, building envelope, heating and cooling systems, water conservation, and acoustics. Energy cost savings are also discussed.

  6. Trading Freshness for Performance in Distributed Systems

    DTIC Science & Technology

    2014-12-01

    Systems (IOPADS ’99), May 1999. 3.6 Charles Babcock. Data, data, everywhere. Information Week, January 2006. 3.2 Peter Bailis, Shivaram Venkataraman ... Venkataraman , Michael J. Franklin, Joseph M. Hellerstein, and Ion Stoica. Pbs at work: Advancing data management with consistency metrics. In Proceedings of...5. doi: 10.1145/2463676.2465260. URL http://doi.acm.org/10. 1145/2463676.2465260. 2.4 Peter Bailis, Shivaram Venkataraman , Michael J. Franklin, Joseph

  7. Review Article: Yamada, Jeni "Laura: A Case for the Modularity of Language"; Tomasello, Michael "First Verbs: A Case Study of Early Grammatical Development."

    ERIC Educational Resources Information Center

    Shatz, Marilyn

    1994-01-01

    Jeni Yamada's "Laura" and Michael Tomasello's "First Verbs" continue a tradition of providing useful information on the language ability of individuals in a depth rarely found in multisubject studies; however, these efforts are unusual for case studies in that both take strong theoretical positions on the essence of language and language learning.…

  8. The Future of Professional Development Will Be Designed, Not Discovered: Response to Moon, Passmore, Reiser, and Michaels, "Beyond Comparisons of Online versus Face-to-Face PD"

    ERIC Educational Resources Information Center

    Fishman, Barry; Konstantopoulos, Spyros; Kubitskey, Beth W.; Vath, Richard; Park, Gina; Johnson, Heather; Edelson, Daniel

    2014-01-01

    This article represents a response to the authors' "Journal of Teacher Education" ("JTE") article (Fishman et al., 2013) by Moon, Passmore, Reiser, and Michaels (2013). The authors believe that Moon et al. have properly identified both the value in their study and the importance of moving beyond not only their study, but…

  9. Michael Francis Madelin (1931--2007): a pioneer in the biology and ecology of conidial fungi and slime moulds.

    PubMed

    Campbell, Richard

    2008-12-01

    Michael F Madelin (1931--2007) was Programme Secretary, Vice-President, and President of the British Mycological Society. A summary of his research on Coprinopsis, various conidial fungi, Coelomomyces and myxomycetes is presented, with a full list of his publications. His teaching career was initially at Imperial College, University of London, and then mostly at the University of Bristol.

  10. Adaptive Filter Techniques for Optical Beam Jitter Control and Target Tracking

    DTIC Science & Technology

    2008-12-01

    OPTICAL BEAM JITTER CONTROL AND TARGET TRACKING Michael J. Beerer Civilian, United States Air Force B.S., University of California Irvine, 2006...TECHNIQUES FOR OPTICAL BEAM JITTER CONTROL AND TARGET TRACKING by Michael J. Beerer December 2008 Thesis Advisor: Brij N. Agrawal Co...DATE December 2008 3. REPORT TYPE AND DATES COVERED Master’s Thesis 4. TITLE AND SUBTITLE Adaptive Filter Techniques for Optical Beam Jitter

  11. Michael Griffin Senate Confirmation Hearing

    NASA Image and Video Library

    2005-04-12

    U.S. Senator Daniel K. Inouye, D-Hawaii, left, speaks as U.S. Senator Ted Stevens, R-Alaska, looks on during the confirmation hearing for Dr. Michael Griffin, in front of the U.S. Senate Commerce Committee, Tuesday, April 12, 2005, in Washington. If confirmed, Griffin, who currently heads the space department at the Johns Hopkins University Applied Physics Laboratory will become NASA's 11th administrator. Photo Credit (NASA/Renee Bouchard)

  12. "Integration was a Solution to Segregation, but Integration does not Address Quality Education": A Conversation about School Desegregation with Dr. Michael A. Middleton

    ERIC Educational Resources Information Center

    Diem, Sarah; Brooks, Jeffrey

    2013-01-01

    We conclude this special issue reflecting back on the history of desegregation and questioning how we move forward in trying to achieve racially integrated school settings. The epilogue includes a conversation with Dr. Michael A. Middleton, Deputy Chancellor of the University of Missouri-Columbia. Dr. Middleton is an expert in civil rights and…

  13. N719 dye-sensitized organophotocatalysis: enantioselective tandem Michael addition/oxyamination of aldehydes.

    PubMed

    Yoon, Hyo-Sang; Ho, Xuan-Huong; Jang, Jiyeon; Lee, Hwa-Jung; Kim, Seung-Joo; Jang, Hye-Young

    2012-07-06

    A remarkably efficient photosensitizer, N719 dye, was used in asymmetric tandem Michael addition/oxyamination of aldehydes, rendering α,β-substituted aldehydes in good yields with excellent levels of enantioselectivity and diastereoselectivity. This is the first report of a multiorganocatalytic reaction involving iminium catalysis and photoinduced singly occupied molecular orbital (SOMO) catalysis. This reaction is expected to expand the scope of tandem organocatalytic reactions.

  14. Immune Cells, if Rendered Insensitive to Transforming Growth Factorbeta, Can Cure Prostate Cancer

    DTIC Science & Technology

    2007-02-01

    Robert E. Meyer,2 Shilajit Kundu,1 Michael Pins,2 Borko Javonovic,3 Timothy Kuzel,4 Seong-Jin Kim,5 Luk Van Parijs,6 Norm Smith,1 Larry Wong,1 Norman M...Zhang,1 Ximing Yang,2,5 Shilajit D. Kundu,1 Michael Pins,2,5 Borko Javonovic,3,5 Robert Meryer,2 Seong-Jin Kim,7 Norman M. Greenberg,8 Timothy Kuzel

  15. Treatment of Laser Induced Retinal Injuries

    DTIC Science & Technology

    1985-01-01

    AD TREATMENT OF LASER INDUCED RETINAL INJURIES cANNUAL/FINAL REPORT MICHAEL BELKIN INAVA NAVEH JANUARY 1985 Supported by U.S. ARMY MEDICAL RESEARCH...CF ,I446 11. TITLE (Include Security Classification) (U) Treatment of Laser Induced Retinal Injuries 12. PERSONAL AUTHOR(S) Michael Belkin 13a. TYPE...ciliary body as seen in uveitis , is associated by elevation of aqueous humor protein levels. Therefore, protein was used by some investigators as an

  16. Development of New Generation of Multibody System Computer Codes

    DTIC Science & Technology

    2012-11-02

    Illinois at Chicago, 842 West Taylor Street, Chicago, IL 60607 Paramsothy Jayakumar Michael D. Letherwood U.S. Army RDECOM-TARDEC, 6501 E. 11 Mile...NUMBER W56HZV-13-C-0032 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Ahmed Shabana; Paramsothy Jayakumar ; Michael Letherwood 5d...public release. UNCLASSIFIED: Distribution Statement A. Approved for public release. REFERENCES 1. Contreras, U., Jayakumar , P., Letherwood, M

  17. Michael Griffin Senate Confirmation Hearing

    NASA Image and Video Library

    2005-04-12

    U.S. Senator Barbara Mikulski, D-Md., testifies before the U.S. Senate Commerce Committee during the confirmation hearing of Dr. Michael Griffin, rear center, Tuesday, April 12, 2005, at the Russell Senate Office Building in Washington. Griffin currently heads the space department at Johns Hopkins University's Applied Physics Laboratory. If confirmed by the full U.S. Senate, Dr. Griffin would be NASA's 11th administrator. Photo Credit: (NASA/Renee Bouchard)

  18. Michael Griffin Senate Confirmation Hearing

    NASA Image and Video Library

    2005-04-11

    U.S. Senator Barbara Mikulski, D-Md., testifies before the U.S. Senate Commerce Committee during the confirmation hearing of Dr. Michael Griffin, rear center, Tuesday, April 12, 2005, at the Russell Senate Office Building in Washington. Griffin currently heads the space department at Johns Hopkins University's Applied Physics Laboratory. If confirmed by the full U.S. Senate, Dr. Griffin would be NASA's 11th administrator. Photo Credit: (NASA/Renee Bouchard)

  19. Michael Griffin Senate Confirmation Hearing

    NASA Image and Video Library

    2005-04-12

    U.S. Senator Barbara Mikulski, D-Md., testifies before the U.S. Senate Commerce Committee during the confirmation hearing of Dr. Michael Griffin, right background, Tuesday, April 12, 2005, at the Russell Senate Office Building in Washington. Griffin currently heads the space department at Johns Hopkins University's Applied Physics Laboratory. If confirmed by the full U.S. Senate, Dr. Griffin would be NASA's 11th administrator. Photo Credit: (NASA/Renee Bouchard)

  20. Generation of Tutorial Dialogues: Discourse Strategies for Active Learning

    DTIC Science & Technology

    1998-05-29

    AND SUBTITLE Generation of Tutorial Dialogues: Discourse Strategies for active Learning AUTHORS Dr. Martha Evens 7. PERFORMING ORGANI2ATION NAME...time the student starts in on a new topic. Michael and Rovick constantly attempt to promote active learning . They regularly use hints and only resort...Controlling active learning : How tutors decide when to generate hints. Proceedings of FLAIRS 󈨣. Melbourne Beach, FL. 157-161. Hume, G., Michael

  1. KENNEDY SPACE CENTER, FLA. -- KSC management and other employees gather in the Center’s television studio to watch the address by President George W. Bush at NASA Headquarters in Washington, D.C., stating his goals for NASA’s new mission: Completing the International Space Station, retiring the Space Shuttle orbiters, developing a new crew exploration vehicle, and returning to the moon and beyond within the next two decades. Pres. Bush was welcomed by NASA Administrator Sean O’Keefe and Expedition 8 Commander Michael Foale, who greeted him from the International Space Station. Members of the Washington, D.C., audience included astronauts Eileen Collins, Ed Lu and Michael Lopez-Alegria, and former astronaut Gene Cernan.

    NASA Image and Video Library

    2004-01-14

    KENNEDY SPACE CENTER, FLA. -- KSC management and other employees gather in the Center’s television studio to watch the address by President George W. Bush at NASA Headquarters in Washington, D.C., stating his goals for NASA’s new mission: Completing the International Space Station, retiring the Space Shuttle orbiters, developing a new crew exploration vehicle, and returning to the moon and beyond within the next two decades. Pres. Bush was welcomed by NASA Administrator Sean O’Keefe and Expedition 8 Commander Michael Foale, who greeted him from the International Space Station. Members of the Washington, D.C., audience included astronauts Eileen Collins, Ed Lu and Michael Lopez-Alegria, and former astronaut Gene Cernan.

  2. Vadose zone monitoring strategies to control water flux dynamics and changes in soil hydraulic properties.

    NASA Astrophysics Data System (ADS)

    Valdes-Abellan, Javier; Jiménez-Martínez, Joaquin; Candela, Lucila

    2013-04-01

    For monitoring the vadose zone, different strategies can be chosen, depending on the objectives and scale of observation. The effects of non-conventional water use on the vadose zone might produce impacts in porous media which could lead to changes in soil hydraulic properties, among others. Controlling these possible effects requires an accurate monitoring strategy that controls the volumetric water content, θ, and soil pressure, h, along the studied profile. According to the available literature, different monitoring systems have been carried out independently, however less attention has received comparative studies between different techniques. An experimental plot of 9x5 m2 was set with automatic and non-automatic sensors to control θ and h up to 1.5m depth. The non-automatic system consisted of ten Jet Fill tensiometers at 30, 45, 60, 90 and 120 cm (Soil Moisture®) and a polycarbonate access tube of 44 mm (i.d) for soil moisture measurements with a TRIME FM TDR portable probe (IMKO®). Vertical installation was carefully performed; measurements with this system were manual, twice a week for θ and three times per week for h. The automatic system composed of five 5TE sensors (Decagon Devices®) installed at 20, 40, 60, 90 and 120 cm for θ measurements and one MPS1 sensor (Decagon Devices®) at 60 cm depth for h. Installation took place laterally in a 40-50 cm length hole bored in a side of a trench that was excavated. All automatic sensors hourly recorded and stored in a data-logger. Boundary conditions were controlled with a volume-meter and with a meteorological station. ET was modelled with Penman-Monteith equation. Soil characterization include bulk density, gravimetric water content, grain size distribution, saturated hydraulic conductivity and soil water retention curves determined following laboratory standards. Soil mineralogy was determined by X-Ray difractometry. Unsaturated soil hydraulic parameters were model-fitted through SWRC-fit code and ROSETTA based on soil textural fractions. Simulation of water flow using automatic and non-automatic date was carried out by HYDRUS-1D independently. A good agreement from collected automatic and non-automatic data and modelled results can be recognized. General trend was captured, except for the outlier values as expected. Slightly differences were found between hydraulic properties obtained from laboratory determinations, and from inverse modelling from the two approaches. Differences up to 14% of flux through the lower boundary were detected between the two strategies According to results, automatic sensors have more resolution and then they're more appropriated to detect subtle changes of soil hydraulic properties. Nevertheless, if the aim of the research is to control the general trend of water dynamics, no significant differences were observed between the two systems.

  3. The Impact of Socio-Cultural Differences on Educational Values: A Comparison of the Pedagogy of Michael Oakeshott and John McGahern

    ERIC Educational Resources Information Center

    Williams, Kevin

    2017-01-01

    The year 2016 marked the tenth anniversary of the death of John McGahern (born 1934), the widely acclaimed Irish author. There is a shared temper of mind and several common strands in the work of McGahern and that of the English philosopher, Michael Oakeshott (1900-1990). Despite the very different cultural environments in which they grew up and…

  4. Computer-Based Instruction Authoring Tools System (CATS): Lesson Maintenance

    DTIC Science & Technology

    1990-07-01

    Tols-System ( CATS ): Lesson Maintenance Vol N. Hutton Michael R. Flaningam Barbara Tarker Ann Rybowlak Susan Sulzbach Mark Lyon Brian Thomason DTC"",~1...Authoring Tools &ystem ( CATS ): Lesson Maintenance Vel N. Hulton Michael R. Flaningam Barbara Tarker Ann Rybowiak Navy Personnel Research and...lools •ystem ( CATS ): Program Element 0604722A Lesson Maintenance 6. AUTHOR(S) V. N. Huhoa, N. R. Fl1ingam. B. Tarktr, A. Rybowiak. S. Sulzbach. M

  5. Using Heart Rate to Predict Resilience and Susceptibility to PTSD in Soldiers

    DTIC Science & Technology

    2011-04-01

    Predict Resilience and Susceptibility to PTSD in Soldiers Authors Brian Chung Jonathan Lanier Lolita M. Burrell Michael D. Matthews...AUTHOR(S) Brian Chung; Jonathan Lanier; Lolita Burrell; Michael Matthews 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING...members of the control group were matched with one of the trauma or PTSD victims based on age and sex and both individuals were shown the same

  6. 2016 Summer Series - Michael Flynn - Synthetic Biological Membrane

    NASA Image and Video Library

    2016-08-02

    Full understanding leads to creation capability, which results in customization capacity. Synthetic biology uses our knowledge of biology to engineer novel biological devices or organisms that can perform tasks not found in nature. For Human space exploration, synthetic biology approaches will reduce risk, mass carried and increase Human reach. Michael Flynn will discuss the International Space Station (ISS) water recycling and his current work on developing a water filtration system capable of self-repair.

  7. Structure of adducts of isoindolo[2,1-a]benzimidazole derivatives with maleimides

    NASA Astrophysics Data System (ADS)

    Korolev, Oleksandr; Yegorova, Tatyana; Levkov, Igor; Malytskyy, Volodymyr; Shishkin, Oleg; Zubatyuk, Roman; Palamarchuk, Genadiy; Vedrenne, Marc; Baltas, Michel; Voitenko, Zoia

    2015-03-01

    The selectivity of formation and some mechanistic insights during the synthesis of substituted isoindolo[2,1-a]benzimidazoles are discussed. Furthermore, the reactions of the obtained products with maleimides were carried out. Two types rearrangement adducts together with intermediate Michael type adducts were isolated. The influence of the reaction conditions and reagents ratio is discussed. Specific spectral criteria for the identification of the Michael type adducts are indicated.

  8. Basic-functionalized recyclable ionic liquid catalyst: A solvent-free approach for Michael addition of 1,3-dicarbonyl compounds to nitroalkenes under ultrasound irradiation.

    PubMed

    Narayanaperumal, Senthil; da Silva, Rodrigo César; Feu, Karla Santos; de la Torre, Alexander Fernández; Corrêa, Arlene G; Paixão, Márcio Weber

    2013-05-01

    A task-specific ionic liquid (TSIL) has been introduced as a recyclable catalyst in Michael addition. A series of nitroalkenes and various C-based nucleophiles were reacted in the presence of 30mol% of recyclable basic-functionalized ionic liquid. Good to excellent yields were obtained in 30min under ultrasound irradiation. Copyright © 2012 Elsevier B.V. All rights reserved.

  9. Controlling Cocaine. Supply Versus Demand Programs

    DTIC Science & Technology

    1994-01-01

    System Description of the Cocaine Trade, MR-236-A/AF/DPRC, Santa Monica, CA. RAND. * Kennedy, Michael, Peter Reuter, and Kevin Jack Riley (1994), A Simple...Peter Reuter, and Kevin Riley, and reviews by Richard Harwood, James Hodges, and Michael Kennedy deepened and improved this analysis. Helpful...relative to rean-ltaonprice Priefti 1.000 Actual heavy- waer treatment cost ($ mn~lons) TreatCost 9M.0 Total control budget ($ naions) Sofludgat.TrSdgate’o

  10. Demonstration of Laser-Induced Fluorescence on Krypton Hall Effect Thruster

    DTIC Science & Technology

    2011-08-10

    5b. GRANT NUMBER Thruster 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) William A. Hargus Jr., Gregory X. Azarnia, and Michael R. Nakles 5d. PROJECT... William A. Hargus, Jr. a. REPORT Unclassified b. ABSTRACT Unclassified c. THIS PAGE Unclassified SAR 13 19b. TELEPHONE NUMBER (include...Thruster William A. Hargus, Jr.∗ Gregory M. Azarnia† Michael R. Nakles‡ Air Force Research Laboratory, Edwards Air Force Base, CA 93524 There is growing

  11. Deals Among Rational Agents,

    DTIC Science & Technology

    1985-03-01

    ARD-AI57 966 DEALS AMONG RATIONAL AGENTS(U) STANFORD UNIV CA DEPT OF 1/1lit COMPUTER SCIENCE J S ROSENSCHEIN ET AL. MAR 857 STAN-CS-85-1e42 NOO039-83... Rational Agents by Jeffrey S. Rosenschemn Michael R. Genesereth Contract N00039-83-c-0136 Department of Computer Science Stanford University Stanford, CA... Rational Agents Jeffrey S. Rosenschein Michael R. Genesereth COMPUTER SCIENCE DEPARTME NT Stanford University Sta-;!ord, California 94305 A ~ ,2 TA

  12. Computational Characterization of Electromagnetic Field Propagation in Complex Structures

    DTIC Science & Technology

    1998-04-10

    34Computational characterization of electromagnetic field propagation in complex structures", DAAH01-91-D-ROOS D.O. 59. Dr. Michael Scalora performed the...Development, and Engineering Center, Bldg. 7804, Room 242 Redstone Arsenal, Alabama 35898-5248 USA Dr. Michael Scalora Quantum Optics Group Tel:(205...scheduled to appear. They are: (1) M. Scalora , J.P. Dowling, A.S. Manka, CM. Bowden, and J.W. Haus, Pulse Propagation Near Highly Reflective

  13. The Role of Data and Feedback Error in Inference and Prediction

    DTIC Science & Technology

    1998-06-01

    O’Connor Bowling Green State University Research and Advanced Concepts Office Michael Drillings, Chief This Document Contains Missing Page/s...Bowling Green State University Technical Review by Michael Drillings, ARI NOTICES DISTRIBUTION: This Research Note has been cleared for release to...0601102A 2O161102B74F TA 1012 WU C06 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) Bowling Green State University , 120 Mcfall Center, Research

  14. Surface Layer Processes And Nocturnal Low Level Jet Development--An Observational Study During Pecan

    DTIC Science & Technology

    2016-12-01

    PROCESSES AND NOCTURNAL LOW-LEVEL JET DEVELOPMENT—AN OBSERVATIONAL STUDY DURING PECAN by Michael K. Beall December 2016 Thesis Advisor... OBSERVATIONAL STUDY DURING PECAN 5. FUNDING NUMBERS 6. AUTHOR(S) Michael K. Beall 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) Naval Postgraduate... research project and collected high-resolution stable boundary layer data as it evolved through the night. The objective of this study was to use this

  15. What We Know about Adolescents' Out-of-School Literacies, What We Need to Learn, and Why Studying Them Is Important: An Interview with Michael W. Smith

    ERIC Educational Resources Information Center

    Smith, Michael W.; Moore, David W.

    2012-01-01

    Michael W. Smith, a professor in Temple University's College of Education, focuses his research on how experienced readers read and talk about texts as well as what motivates adolescents' reading and writing in and out of school. He sees the recent research on adolescents' out-of-school literacies as a challenge to literacy educators to look at…

  16. Adam's Rage: Children of the Pinelands Speak: The Michael L. Printz Award Winning Novels: Authentic Current Literature as a Catalyst for Increased Student Growth, Motivation and Healing

    ERIC Educational Resources Information Center

    Cecchini, Stephanie Anne

    2012-01-01

    Young adults deserve our best as parents, educators and community members. The Michael L. Printz award winning books, instituted by the Young Adult Library Association, form a recent grouping of current literature. Novels worthy of the Printz Award explore physical, emotional, and social themes important in the lives of young adults. This library…

  17. An Investigation of Wing Lift Augmentation with Spanwise Tip Blowing.

    DTIC Science & Technology

    1987-04-22

    ON8 Michael R. Mendenhall Steven C. CarusoS Co) D Daniel J. Lesieutre Nielsen Engineering & Research, Inc. 510 Clyde Avenue Mountain View, CA 94043...Augmentation with Spanwise Tip Blowing 12. PERSONALAUTHOR(S) Michael R. Mendenhall, Steven C. Caruso, Daniel J. Lesieutre, and Robert E. Childs 13a. TYPE OF...hardware and associated electronics for the flowfield survey 99 traverse rig mechanism. Mrs. Susana N. Nazario contributed tne software necessary for the

  18. Prediction of the Aerodynamic Characteristics of Cruciform Missiles Including Effects of Roll Angle and Control Deflection

    DTIC Science & Technology

    1986-08-01

    CHARACTERISTICS OF CRU.CIFORM MISSILES INCLUDING EFFECTS OF ROLL ANGLE AND CONTROL DEFLECTION N by Daniel J. Lesieutre Michael R. Mendenhall Susana M. Nazario...ANGLE AND CONTROL DEFLECTION Daniel J. Lesieutre Michael R. Mendenhal. Susana M. Nazario Nielsen Engineering & Research, Inc.00 Mountain View, CA 94043...Lo PREDICTION OF THE AERODYNAMIC CHARACTERISTICS OF CRU.CIFORM MISSILES - INCLUDING EFFECTS OF ROLL ANGLE AND CONTROL DEFLECTION by Daniel J

  19. Acquisition Review Quarterly (ARQ): Volume 10, Number 3, Summer 2003

    DTIC Science & Technology

    2003-01-01

    PROJECT NUMBER Lt Col Robert L. Waller, USAF, (Ret), Robert Graham, Maj David R. King, USAF, Lt Col John D. Driessnack, USAF, LTC Michael D. Proctor...High-Technology Industries Implications for Industrial Policy Maj David R. King, USAF Lt Col John D. Driessnack, USAF Why the "T" in SMART A...Business School William H . Reed Director Michael Wynne Defense Contract Audit Agency Acting Under Secretary of Defense (Acquisition, Technology, and

  20. The Sound of Freedom. Naval Weapons Technology at Dahlgren, Virginia, 1918-2006

    DTIC Science & Technology

    2006-01-01

    the TRINITY device, before later succeeding J. Robert Oppenheimer as the director of Los Alamos National Laboratory. Other former Dahlgren...and the Computer (Cambridge, Mass.: The MIT Press, 1999); Michael R. Williams, A History of Computing Technology, 2nd ed. ( Los Alamos , Calif.: IEEE...Minutes of Advisory Council. 3. Ibid. 4. Ibid.; Michael R. Williams, A History of Computing Technology, 2nd ed. ( Los Alamos , Calif.: IEEE Computer

  1. CHMWTR: A Plasma Chemistry Code for Water Vapor

    DTIC Science & Technology

    2012-02-01

    Naval Research Laboratory Washington, DC 20375-5320 NRL/MR/6790--12-9383 CHMWTR: A Plasma Chemistry Code for Water Vapor Daniel F. GorDon Michael...NUMBER OF PAGES 17. LIMITATION OF ABSTRACT CHMWTR: A Plasma Chemistry Code for Water Vapor Daniel F. Gordon, Michael H. Helle, Theodore G. Jones, and K...October 2011 NRL *Directed Energy Scholar, Directed Energy Professional Society Plasma chemistry Breakdown field Conductivity 67-4270-02 CHMWTR: a Plasma

  2. Privatized Military Operations. Industry Study, Spring 2009

    DTIC Science & Technology

    2009-01-01

    to the nation. Ms. Kathy Aydt, Dept of Army GPCAPT Rob Barnes, Royal Australian Air Force COL Michael Bird, US Army CAPT Bruce Breth, US Navy ...Force CDR Ron Foy, US Navy COL Michael Hoskin, US Army Col Doug McCarthy, Canadian Forces Lt Col William Murphey, US Air Force COL Broc Perkuchin...Wellington, New Zealand Royal New Zealand Navy Logistics, Devonport Naval Base, Auckland, New Zealand VT Fitzroy, Devonport Naval Base, Auckland, New

  3. Improving the Cybersecurity of U.S. Air Force Military Systems Throughout Their Life Cycles

    DTIC Science & Technology

    2015-01-01

    James D. Powers, Elizabeth Bodine-Baron, Bernard Fox, Lauren Kendrick, Michael H. Powell Report Documentation Page Form ApprovedOMB No. 0704...Rational, Natural, and Open Systems, 3rd ed., Englewood Cliffs, N.J.: Prentice Hall, 1992. 61 Snyder, Don, Bernard Fox, Kristin F. Lynch, Raymond E...Conley, John A. Ausink, Laura Werber , William Shelton, Sarah A. Nowak, Michael R. Thirtle, and Albert A. Robbert, Assessment of the Air Force

  4. Assessment of the Air Force Materiel Command Reorganization: Report for Congress

    DTIC Science & Technology

    2013-01-01

    Report for Congress Don Snyder, Bernard Fox, Kristin F. Lynch, Raymond E. Conley, John A. Ausink, Laura Werber , William Shelton, Sarah A. Nowak, Michael... Bernard Fox, Kristin F. Lynch, Raymond E. Conley, John A. Ausink, Laura Werber , William Shelton, Sarah A. Nowak, Michael R. Thirtle, Albert A. Robbert...Ausink, Chelsea Kaihoi Duran, Robert G. DeFeo, David W. George, Raymond E. Conley, Bernard Fox, and Jerry M. Sollinger, Air Force Materiel Command

  5. Preparation for a Clinical Trial Using Adoptive Transfer of Tumor-Reactive TGF_Beta-Insensitive CD8+ T Cells for Treatment of Prostate Cancer

    DTIC Science & Technology

    2006-07-01

    TumorCells Qiang Zhang,1 Thomas L. Jang,1 Ximing Yang,2 Irwin Park,1 Robert E. Meyer,2 Shilajit Kundu,1 Michael Pins,2 Borko Javonovic,3 Timothy Kuzel,4...reactive CD8+ T cells activates the antitumor immune response cycle Qiang Zhang,1 Ximing Yang,2,5 Shilajit D. Kundu,1 Michael Pins,2,5 Borko Javonovic

  6. STS-69 MS Michael L. Gernhardt greets his mother at SLF

    NASA Technical Reports Server (NTRS)

    1995-01-01

    STS-69 Mission Specialist Michael L. Gernhardt (right) gets a chance to say hi to his mother, Suzanne Winters, and her husband Doug, after the STS-69 flight crew arrived at KSC's Shuttle Landing Facility. The five astronauts assigned to the mission are looking forward to a liftoff aboard the Space Shuttle Endeavour during a two and a half hour window opening at 11:09 a.m. EDT, Sept. 7.

  7. Chain Dynamic Formulations for Multibody System Tracked Vehicles

    DTIC Science & Technology

    2012-08-01

    CONTRACT NUMBER W911NF-07-D-0001 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Paramsothy Jayakumar ; Michael Letherwood; Michael Wallin...Hamed, M. A., Shabana, A. A., Jayakumar , P., and Letherwood, M. D., 2011, “Nonstructural geometric discontinuities in finite element/multibody system... Jayakumar , P., and Letherwood, M. D. 2012, “Use of B- Spline in the Finite Element Analysis: Comparison with ANCF Geometry,” Journal of Computational and

  8. Retracted manuscript

    PubMed Central

    Klockars, Anica

    2013-01-01

    The following article from Small GTPases, “Scientific Yellow Journalism” by Anica Klockars and Michael J. Williams, published online on 20 September 2012  (doi: 10.4161/sgtp.22289; http://www.landesbioscience.com/journals/smallgtpases/article/22289/) by Landes Bioscience and subsequently published in print in Small GTPases 2012 3(4):201 has been retracted by agreement between the authors and the journal’s Editor in Chief, Michael J. Williams (also an author of the paper).  PMID:23485921

  9. A Cost-Benefit Analysis of the LAV Mobility and Obsolescence Program by Using U.S. Army Stryker Suspensions

    DTIC Science & Technology

    2015-06-01

    OBSOLESCENCE PROGRAM BY USING U.S. ARMY STRYKER SUSPENSIONS June 2015 By: Chad D. Harmon and Michael Z. Keathley Advisors: Amilcar Menichini...THE LAV MOBILITY AND OBSOLESCENCE PROGRAM BY USING U.S. ARMY STRYKER SUSPENSIONS 5. FUNDING NUMBERS 6. AUTHOR(S) Chad D. Harmon and Michael Z...bolster their light armored reconnaissance battalions. 14. SUBJECT TERMS Cost benefit analysis, mobility and obsolescence , LAV

  10. Michael K. Scullin: Psi Chi/APA Edwin B. Newman Graduate Research Award.

    PubMed

    2011-11-01

    Presents Michael K. Scullin as the 2011 winner of the American Psychological Association Psi Chi/APA Edwin B. Newman Graduate Research Award. "For an outstanding research paper that examines the relationship between prospective memory in executing a goal and various lapses of time from 20 minutes up to a 12- hour wake delay and a 12-hour sleep delay. The results suggest that consolidation processes active during sleep increase the probability of goal execution. The paper, titled 'Remembering to Execute a Goal: Sleep On It!' was published in Psychological Science in 2010 and was the basis for Michael K. Scullin's selection as the recipient of the 2011 Psi Chi/APA Edwin B. Newman Graduate Research Award. Mark A. McDaniel, PhD, served as faculty research advisor." (PsycINFO Database Record (c) 2011 APA, all rights reserved). 2011 APA, all rights reserved

  11. [An exceptional human relationship (Michael P. Kierkegaard, Søren Kierkegaard)].

    PubMed

    Jacobs, R

    1978-01-01

    There were a father and a son, Michael and Sören Kierkegaard, both highly talented, imaginitive, witty, humorous, especially interested in shrewd dialectrical dialogues respectively debates, both profound melancholy ponderers. But according to very own individuality their congeniality wasn't absolute. The father, being under a questionable rigorous opinion of sin, suffered from undeserved divine grace since early childhood. And Michael Kierkegaard made Sören anxious with the religious experience of original sin. This anxiety moved (touched or affected) the sensitive son mighty. Nevertheless he should not despair hopelessly like his unlucky father. On the contrary: Sørens incomparable melancholy, mental agony and anxiety (fear or anguish) forced the faith, existing independently of them, in a radical refining. That is why Sören Kierkegaard succeeded in sublimation of all psychological and philosophic (al) attitudes (or opinions) in the sphere of religiousness. And the result? A novel philosophy of life: Christian existentialism.

  12. Superelastic and pH-Responsive Degradable Dendrimer Cryogels Prepared by Cryo-aza-Michael Addition Reaction.

    PubMed

    Wang, Juan; Yang, Hu

    2018-05-08

    Dendrimers exhibit super atomistic features by virtue of their well-defined discrete quantized nanoscale structures. Here, we show that hyperbranched amine-terminated polyamidoamine (PAMAM) dendrimer G4.0 reacts with linear polyethylene glycol (PEG) diacrylate (575 g/mol) via the aza-Michael addition reaction at a subzero temperature (-20 °C), namely cryo-aza-Michael addition, to form a macroporous superelastic network, i.e., dendrimer cryogel. Dendrimer cryogels exhibit biologically relevant Young's modulus, high compression elasticity and super resilience at ambient temperature. Furthermore, the dendrimer cryogels exhibit excellent rebound performance and do not show significant stress relaxation under cyclic deformation over a wide temperature range (-80 to 100 °C). The obtained dendrimer cryogels are stable at acidic pH but degrade quickly at physiological pH through self-triggered degradation. Taken together, dendrimer cryogels represent a new class of scaffolds with properties suitable for biomedical applications.

  13. Preparing for and Observing the 2017 Total Solar Eclipse

    NASA Astrophysics Data System (ADS)

    Pasachoff, J.

    2015-11-01

    I discuss ongoing plans and discussions for EPO and scientific observing of the 21 August 2017 total solar eclipse. I discuss aspects of EPO based on my experiences at the 60 solar eclipses I have seen. I share cloud statistics along the eclipse path compiled by Jay Anderson, the foremost eclipse meteorologist. I show some sample observations of composite imagery, of spectra, and of terrestrial temperature changes based on observations of recent eclipses, including 2012 from Australia and 2013 from Gabon. Links to various mapping sites of totality, partial phases, and other eclipse-related information, including that provided by Michael Zeiler, Fred Espenak (retired from NASA) and Xavier Jubier can be found on the website I run for the International Astronomical Union's Working Group on Eclipses at http://www.eclipses.info.

  14. Direct synthesis and application of bridged diamino-functionalized periodic mesoporous organosilicas with high nitrogen contents

    NASA Astrophysics Data System (ADS)

    Zhu, Feng-Xia; Zhao, Pu-Su; Sun, Xiao-Jun; An, Li-Tao; Deng, Yong; Wu, Jia-Min

    2017-11-01

    Bridged diamino-functionalized periodic mesoporous organosilicas [BD-PMO(Et), Et = ethyl] materials were synthesized directly by co-condensation of 2-bis (triethoxysilyl)ethane (BTEE) and 1,4-bis[3-(tirmethoxysilyl)-propyl]ethylenediamino (BTMSEN) under acidic conditions with pluronic triblock copolymer P123 as a template. The nitrogen content in BD-PMO(Et) could be adjusted up to 40% without disturbing the ordered mesoporous structure. These materials were proved to be effective heterogeneous catalysts for the liquid-phase reactions such as Knoevenagel and Henry condensations as well as in the intermolecular cross-double-Michael addition reaction between α-methyl-β-nitrostyrene and α, β-unsaturated ketone. They exhibited comparable catalytic activities with homogeneous catalyst piperazine and can be reused for several times without any negative environmental impact.

  15. Reisen im freien Fall - Teil 2: Das Zwillingsparadoxon aus dem Blickwinkel der ART

    NASA Astrophysics Data System (ADS)

    Sonne, Bernd; Weiß, Reinhard

    2013-07-01

    Nachdem wir uns mit den Prinzipien der ART und einigen Beispielen vertraut gemacht haben, kommen wir nun zur Berechnung des Zwillingsparadoxons aus Sicht des reisenden Zwillings. Dabei spielt das Äquivalenzprinzip eine große Rolle. Deshalb wird die Bewegungssituation noch einmal erläutert, diesmal aus Sicht von Katrin. Sie befindet sich in ihrem System S'in Ruhe. In ihrem System läuft die Zeit t'ab. Nach dem Start fühlt Katrin jedoch eine Kraft, die sie als Gravitationskraft interpretieren kann. Sie merkt es daran, dass sie in den Sitz gedrückt wird. Nach einiger Zeit werden die Triebwerke abgeschaltet, und das Raumschiff fliegt mit konstanter Geschwindigkeit weiter, Phase 2. Anschließend wird der Schub der Triebwerke solange umgekehrt, bis das Raumschiff irgendwo mit der Geschwindigkeit null am Umkehrpunkt U landet, Phase 3 (Abb. 15.1). Die Erde, auf der sich Michael befindet, bewegt sich mit x'(t') aus Sicht von Katrin im freien Fall von ihr weg, s. das Experiment mit dem steigenden Fahrstuhl in Abschn. 13.2.1.

  16. Coalition Logistics: A Case Study in Operation Restore Hope

    DTIC Science & Technology

    1994-06-03

    coalition operations."° In Seland’s interview with Colonel Wolfgang Kopp, chief of staff, German/Franco Brigade, Colonel Kopp stated that key members...February 1994. 21William G. Pagonis and Michael D. Krause , "Operational Logistics and the Gulf War," The Institute of Land Warfare: The Land Warfare...Headquarters, 1989. Pagonis, William G. and Michael D. Krause . "Operational Logistics and the Gulf War." The Land Warfare Paper No. 13. Arlington, Virginia

  17. The Institutionalization of Drug Trafficking Organizations: Comparing Colombia and Brazil

    DTIC Science & Technology

    2010-09-01

    Shifter, “Latin America’s Drug Problem,” Current History (February 2007): 58. 6 Henry Veltmeyer and James Petras , “Social Structure and Change in Latin...In The Oxford Handbook of Public Policy, by Michael Moran, Martin Rein and Robert E. Goodwin (New York, NY: Oxford University Press, 2008), 691...Johan P. Olsen, “Chapter 34: The Logic of Appropriateness.” In The Oxford Handbook of Public Policy, by Michael Moran, Martin Rein and Robert E

  18. Ablative Heat Shield Studies for NASA Mars/Earth Return Entry Vehicles

    DTIC Science & Technology

    1990-09-01

    RETURN ENTRY VEHICLES by Michael K. Hamm September, 1990 NASA Thesis Advisor: William D. Henline Thesis Co-Advisor: Max F. Platzer Approved for public...STUDIES FOR NASA MARS/EARTH RETURN ENTRY VEHICLES (UNCLASSIFIED) 12. PERSONAL AUTHOR(S) Harm, Michael, K. 13a TYPE OF REPORT 13b TIME COVERED 14 DATE OF...theoretical values. The tests were performed to ascertain if RSI type materials could be used for entry vehicles proposed in NASA Mars missions. 20

  19. Air and Space Museum Apollo 40th Celebration

    NASA Image and Video Library

    2009-07-19

    Jazz pianist and singer Diana Krall holds a montage given to her by the STS-125 space shuttle crew along with Apollo 11 Astronaut Neil Armstrong at the Apollo 40th anniversary celebration held at the National Air and Space Museum, Monday, July 20, 2009 in Washington. From left, Michael J. Massimino, Michael T. Good, Gregory C. Johnson, Andrew J. Feustel, Krall, Scott D. Altman, Neil Armstrong, John M. Grunsfeld and Megan McArthur. Photo Credit: (NASA/Bill Ingalls)

  20. Combining silver catalysis and organocatalysis: a sequential Michael addition/hydroalkoxylation one-pot approach to annulated coumarins.

    PubMed

    Hack, Daniel; Chauhan, Pankaj; Deckers, Kristina; Hermann, Gary N; Mertens, Lucas; Raabe, Gerhard; Enders, Dieter

    2014-10-03

    A highly stereoselective one-pot procedure for the synthesis of five-membered annulated hydroxycoumarins has been developed. By merging primary amine catalysis with silver catalysis, a series of functionalized coumarin derivatives were obtained in good yields (up to 91%) and good to excellent enantioselectivities (up to 99% ee) via a Michael addition/hydroalkoxylation reaction. Depending on the substituents on the enynone, the synthesis of annulated six-membered rings is also feasible.

  1. Studies of the Processing of Single Words Using Positron Tomographic Measures of Cerebral Blood Flow Change.

    DTIC Science & Technology

    1987-01-01

    BLOOD FLOW CHANGE Steven E. Petersen, Peter T. Fox, Michael I. Posner, Marcus Raichle McDonnell Center for Studies of Higher Brain Function...Single Words Using Positron Emission Tomographic Measurements of Cerebral Blood Flow Change *= ’I PERSONAL AUTHOR(S) * Petersen, Steven E. 13a. TYPE OF...CHANGE Steven E. Petersen, Peter T. Fox, Michael I. Posner, Marcus E. Raichle INTRODUCTION Language is an essential characteristic of the human

  2. Speech Research. A Report on the Status and Progress of Studies on the Nature of Speech, Instrumentation for its Investigation, and Practical Applications.

    DTIC Science & Technology

    1978-03-01

    Gloria J. Borden* Guy Garden* Robert Crowder* Steven B. Davis Michael Dorman* Donna Erickson William Ewan* Carol A. Fowler* Frances...Robert Crowder* Steven B. Davis Michael Dorman* Donna Erickson William Ewan* Carol A. Fowler* Frances J. Freeman* Jane H. Gaitenby Thomas J...Gibson, 1971; LaBerge and Samuels, 1974; Doehring, 1976; Estes, in press). We distinguish, in particular, between five separate levels of

  3. Magnetohydrodynamic Particle Acceleration Processes: SSX Experiments, Theory, and Astrophysical Applications

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Brown, Michael R.

    2006-11-16

    Project Title: Magnetohydrodynamic Particle Acceleration Processes: SSX Experiments, Theory, and Astrophysical Applications PI: Michael R. Brown, Swarthmore College The purpose of the project was to provide theoretical and modeling support to the Swarthmore Spheromak Experiment (SSX). Accordingly, the theoretical effort was tightly integrated into the SSX experimental effort. During the grant period, Michael Brown and his experimental collaborators at Swarthmore, with assistance from W. Matthaeus as appropriate, made substantial progress in understanding the physics SSX plasmas.

  4. Joint Task Force - Port Opening: Can this Emerging Capability Expedite Operational Objectives Throughout the Range of Military Operations?

    DTIC Science & Technology

    2009-10-26

    for Acquisition, Technology, and Logistics, 30 July 2007). 16 Craig Koontz , ―U.S. Transportation Command,‖ PowerPoint, 23 September 2009, Newport, RI...Support Group. To Lt Col Michael W. Pratt, Naval War College. Memorandum, 30 September 2009. Koontz , Craig. ―U.S. Transportation Command...PowerPoint. 23 September 2009. 22 Koontz , Craig. Contractor/Advisor to CDR U.S. Transportation Command. To Lt Col Michael W. Pratt, 28

  5. Fatigue Management for Aerospace Expeditionary Forces Deployment and Sustained Operations

    DTIC Science & Technology

    2001-04-01

    Aerospace Expeditionary Forces Deployment and Sustained Operations Contract Number Grant Number Program Element Number Author(s) LeClair, Michael A...3. F. Whitten Peters and Michael E. Ryan , US Air Force Posture State­ ment 2000, 30–31. 4. M. R. Rosekind et al., “From Laboratory to Flightdeck...Corporate Aviation Safety Semi­ nar, Flight Safety Foundation, St. Louis, Mo., 1994. 4. Philippa H. Gander, Mark R. Rosekind, and Kevin B. Gregory

  6. Adaptive Problem Solving

    DTIC Science & Technology

    2017-03-01

    AFRL-AFOSR-JP-TR-2017-0026 Adaptive Problem Solving Michael Barley THE UNIVERSITY OF AUCKLAND Final Report 03/01/2017 DISTRIBUTION A: Distribution...May 2015 to 26 Nov 2016 4. TITLE AND SUBTITLE Adaptive Problem Solving 5a.  CONTRACT NUMBER 5b.  GRANT NUMBER FA2386-15-1-4069 5c.  PROGRAM ELEMENT...Report for AOARD Grant FA2386-15-1-4069 “ Adaptive Problem Solving” 25 February 2017 Name of Principal Investigators (PI): Michael W. Barley - e

  7. The 2008 IDA Cost Research Workshop: Contractor Data Reporting Systems

    DTIC Science & Technology

    2008-07-01

    Consulting Services, Ltd. Mr. Michael Carey, NCCA, (703) 692-4901 Mr. Craig Clark, HVR CSL, 011 44 1420 87977 Ms Mary M. Mertz, NSWC-CD, (301) 227-4012...Services, Ltd Mr. Michael Carey, NCCA, (703) 692-4901 Mr. Craig Clark, HVR CSL, 011 44 1420 87977 Ms Mary M. Mertz, NSWC-CD, (301) 227-4012... Deegan , (202) 781-0959 Size: Professional: 57 Support: 2 Consultants: 0 Subcontractors: 9 collocated or 30 total Focus: O&S Cost Estimating

  8. Flexural and Tensile Properties of Thin, Very High-Strength, Fiber-Reinforced Concrete Panels

    DTIC Science & Technology

    2008-09-01

    Fiber - Reinforced Concrete Panels Michael J. Roth September 2008 G eo te ch ni ca l a nd S tr uc tu re s La bo ra to ry Approved for...Tensile Properties of Thin, Very High-Strength, Fiber - Reinforced Concrete Panels Michael J. Roth Geotechnical and Structures Laboratory U.S. Army...of Michigan, Ann Arbor, and noted authority in the field of 160 fiber - reinforced concrete . Implementation of Li’s work

  9. The Michael Reaction

    NASA Astrophysics Data System (ADS)

    Poon, Thomas; Mundy, Bradford P.; Shattuck, Thomas W.

    2002-02-01

    A brief account of the Michael reaction is provided, illustrating its versatility as a topic in undergraduate chemistry courses. Included is a short biography of the reaction's namesake, examples of its use in organic synthesis, and its unique role in the defense mechanism of the bacterium Micromonospora echinospora. A computational rationale for the selectivity of 1,4 versus 1,2 addition of nucleophiles to a,b-unsaturated carbonyls is discussed and links to animations suitable for an introductory organic chemistry course are provided.

  10. Small Business Specialists

    DTIC Science & Technology

    1993-01-01

    AF) Ms. Nicole A. Dillon Williams AFB AC 602/988-6618 85224-5004 Fort Huachuca HQ U.S. Army Information Systems Command (A) Mr. Michael P. Dean* ATTN...Army Medical Center (A) Maj Paul G. Michaels ATTN: HSAA-L Mr. William Brundage Presidio of San Francisco AC 415/561-5473/6289 94124-6700 SUPSHIP...Systems Division AC 408/224-7748 P. 0. Box 49028 95161-9028 San Luis Obispo National Guard (A)(AF) Col William T. Mongold USPFO for California AC 805

  11. Preparation for a Clinical Trial Using Adoptive Transfer of Tumor-Reactive TGF_Beta-Insensitive CD8+ T Cells for Treatment of Prostate Cancer

    DTIC Science & Technology

    2006-07-01

    Park,1 Robert E. Meyer,2 Shilajit Kundu,1 Michael Pins,2 Borko Javonovic,3 Timothy Kuzel,4 Seong-Jin Kim,5 Luk Van Parijs,6 Norm Smith,1 Larry Wong,1...cycle Qiang Zhang,1 Ximing Yang,2,5 Shilajit D. Kundu,1 Michael Pins,2,5 Borko Javonovic,3,5 Robert Meryer,2 Seong-Jin Kim,7 Norman M. Greenberg,8

  12. Diversity oriented synthesis of tricyclic compounds from glycals using the Ferrier and the Pauson-Khand reactions.

    PubMed

    Hotha, Srinivas; Tripathi, Ashish

    2005-01-01

    Diversity oriented synthesis of tricyclic compounds was achieved using a combination of the Ferrier reaction and the Pauson-Khand reaction. Ferrier reaction was effected using NbCl5, and the Pauson-Khand reaction was carried out using Co2(CO)8, acetonitrile-dimethoxyethane. Michael additions using various alkyl, aryl, and heterocyclic thiols were also performed successfully. The Ferrier, Pauson-Khand, and Michael addition reactions were found to be highly diastereoselective.

  13. Organocatalytic asymmetric anti-selective Michael reactions of aldehydes and the sequential reduction/lactonization/Pauson-Khand reaction for the enantioselective synthesis of highly functionalized hydropentalenes.

    PubMed

    Hong, Bor-Cherng; Dange, Nitin S; Yen, Po-Jen; Lee, Gene-Hsiang; Liao, Ju-Hsiou

    2012-10-19

    A new method has been developed for the enantioselective synthesis of highly functionalized hydropentalenes bearing up to four stereogenic centers with high stereoselectivity (up to 99% ee). This process combines an enantioselective organocatalytic anti-selective Michael addition with a highly efficient one-pot reduction/lactonization/Pauson-Khand reaction sequence. The structures and absolute configurations of the products were confirmed by X-ray analysis.

  14. Design of an Advanced Modular Automated Evaluation System for Experimental High Power SGTOS

    DTIC Science & Technology

    2013-06-01

    POWER SGTOS Shelby Lacouture, Kevin Lawson, Stephen Bayne, Michael Giesselmann, Heather O’Brien 1 , Aderinto Ogunniyi 1 , Charles J...Travis T. Vollmer and Michael G. Giesselmann, Rapid Capacitor Charging Power Supply for an 1800J PFN, Proceedings of the 2012 Power Modulator and High Voltage Conference, San Diego, CA, June 3-7, 2012. 1023 ...Scozzie 1 Center for Pulsed Power and Power Electronics Department of Electrical & Computer Engineering Texas Tech

  15. Use of B-Spline in the Finite Element Analysis: Comparison with ANCF Geometry

    DTIC Science & Technology

    2011-02-04

    Beam Elements”, Multibody System Dynamics , Vol. 20 (1), pp. 1-28. 7. Hamed, A.M., Shabana, A.A., Jayakumar , P., and Letherwood, M.D., 2011 “Non...West Taylor Street Chicago, Illinois 60607 Paramsothy Jayakumar Michael D. Letherwood U.S. Army RDECOM-TARDEC 6501 E. 11 Mile Road Warren...Ashraf Hamed; Abdel - Nasser Mohamed; Paramsothy Jayakumar ; Michael Letherwood 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7

  16. The Road to Remarkable: Directed by Vision, Driven by Strength--2010 Five-Year Report of the Policy and Planning Board

    ERIC Educational Resources Information Center

    American Psychologist, 2011

    2011-01-01

    The 2010 Policy and Planning Board of the American Psychological Association (APA) was chaired by Elena J. Eisman, EdD. Other members of the board included Gwyneth M. Boodoo, PhD; G. Rita Dudley-Grant, PhD; Beverly Greene, PhD; Christopher W. Loftis, PhD; Michael J. Murphy, PhD; Paul D. Nelson, PhD; Kurt Salzinger, PhD; and Michael Wertheimer,…

  17. Learning from Consumer-Oriented Review Efforts To Guide the Development of a System of Expert Panels To Identify and Share Promising and Exemplary Products and Programs. Working Papers. Volumes One and Two.

    ERIC Educational Resources Information Center

    Office of Educational Research and Improvement (ED), Washington, DC. Office of Reform Assistance and Dissemination.

    These volumes contain working papers related to the development of the Office of Educational Research and Improvement (OERI) Facilitated System of Expert Panels. Introductory papers by Susan Klein, Michael Scriven, Sharon Bobbitt and Susan Klein, and Michael Scriven and Lois-ellin Datta (printed in both volumes) set the stage for the discussions…

  18. Future Drivers for State Alignments

    DTIC Science & Technology

    2009-02-12

    It’s a Flat World, After All,” Global Issues , 07/08 (Dubuque, IA: McGraw Hill, 2008), 7. Thomas Friedman is an op-ed writer for the New York Times... Global Issues , 07/08 (Dubuque, IA: McGraw Hill, 2008), 62. Joseph Stiglitz is a professor of economics at Columbia University, he has been awarded the...Michael Pettis, “Will Globalization Go Bankrupt?” Global Issues , 07/08 (Dubuque, Iowa: McGraw Hill, 2008), 71. Michael Pettis is an investment banker

  19. User's guide for mapIMG 3--Map image re-projection software package

    USGS Publications Warehouse

    Finn, Michael P.; Mattli, David M.

    2012-01-01

    Version 0.0 (1995), Dan Steinwand, U.S. Geological Survey (USGS)/Earth Resources Observation Systems (EROS) Data Center (EDC)--Version 0.0 was a command line version for UNIX that required four arguments: the input metadata, the output metadata, the input data file, and the output destination path. Version 1.0 (2003), Stephen Posch and Michael P. Finn, USGS/Mid-Continent Mapping Center (MCMC--Version 1.0 added a GUI interface that was built using the Qt library for cross platform development. Version 1.01 (2004), Jason Trent and Michael P. Finn, USGS/MCMC--Version 1.01 suggested bounds for the parameters of each projection. Support was added for larger input files, storage of the last used input and output folders, and for TIFF/ GeoTIFF input images. Version 2.0 (2005), Robert Buehler, Jason Trent, and Michael P. Finn, USGS/National Geospatial Technical Operations Center (NGTOC)--Version 2.0 added Resampling Methods (Mean, Mode, Min, Max, and Sum), updated the GUI design, and added the viewer/pre-viewer. The metadata style was changed to XML and was switched to a new naming convention. Version 3.0 (2009), David Mattli and Michael P. Finn, USGS/Center of Excellence for Geospatial Information Science (CEGIS)--Version 3.0 brings optimized resampling methods, an updated GUI, support for less than global datasets, UTM support and the whole codebase was ported to Qt4.

  20. ER-2 #809 awaits pilot entry for the third flight of the SAGE III Ozone Loss and Validation Experiment (SOLVE)

    NASA Image and Video Library

    2000-01-28

    ER-2 #809 awaiting pilot entry for the third flight of the SAGE III Ozone Loss and Validation Experiment (SOLVE). The ER-2, a civilian variant of Lockheed's U-2, and another NASA flying laboratory, Dryden's DC-8, were based north of the Arctic Circle in Kiruna, Sweden during the winter of 2000 to study ozone depletion as part of SOLVE. A large hangar built especially for research, "Arena Arctica" housed the instrumented aircraft and the scientists. Scientists have observed unusually low levels of ozone over the Arctic during recent winters, raising concerns that ozone depletion there could become more widespread as in the Antarctic ozone hole. The NASA-sponsored international mission took place between November 1999 and March 2000 and was divided into three phases. The DC-8 was involved in all three phases returning to Dryden between each phase. The ER-2 flew sample collection flights between January and March, remaining in Sweden from Jan. 9 through March 16. "The collaborative campaign will provide an immense new body of information about the Arctic stratosphere," said program scientist Dr. Michael Kurylo, NASA Headquarters. "Our understanding of the Earth's ozone will be greatly enhanced by this research."

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