Effects of continuing professional development on clinical performance

PubMed Central

Goulet, François; Hudon, Eveline; Gagnon, Robert; Gauvin, Eliane; Lemire, Francine; Arsenault, Isabelle

2013-01-01

Abstract Objective To evaluate the link between the quantity and quality of continuing professional development (CPD) activities completed by family physicians in Quebec and the quality of their practice. Design Retrospective analysis of data collected during professional inspection visits (PIVs). Setting Quebec. Participants Three groups were created from among Quebec family physicians who had been subject to PIVs (peer evaluation) by the Collège des médecins du Québec between 1998 and 2005. Group 1 was composed of physicians who were members of the College of Family Physicians of Canada, which requires participation in 250 hours of CPD in every 5-year cycle. Group 2 was composed of family physicians who were not members of the College of Family Physicians of Canada but who had declared at least 50 hours a year of CPD on their Collège des médecins du Québec annual notice of assessment for the same period. Group 3 was composed of family physicians who had declared fewer than 10 hours of CPD a year. Main outcome measures During the PIV, the following characteristics were examined: record keeping, quality and number of hours of CPD activities, and quality of professional practice based on 3 components— clinical investigation, accuracy of diagnosis, and appropriateness of treatment plan and follow-up. Results The factors associated with a high quality of practice were privileges in a hospital or local community health centre (institution) and a substantial number of accredited CPD hours (Mainpro-M1, Credit I, or Mainpro-C). The factors associated with a poor quality of practice were advanced age of the physician, absence of privileges in an institution (hospital or local community health centre), and participation in CPD activities that were more informal, such as reading and non-accredited activities (Mainpro-M2). Conclusion This study supports earlier research showing that CPD activities of sufficient quality and quantity are correlated with a high quality of professional practice by family physicians. PMID:23673591

Human Rights and torture.

PubMed

1998-01-01

1998 marks the 50th anniversary of the historic Universal Declaration of Human Rights, which proclaims that all peoples are born free and equal and sets out the basic principles of equality and nondiscrimination in the enjoyment of fundamental freedoms and human rights. Yet, despite the many covenants and conventions stemming from this declaration and signed by nations around the world, human rights continue to be violated by powerful groups, by individuals, often even by family members. On 26 June, which has been declared UN International Day in Support of Victims of Torture, attention will be focused on torture--a grave violation of a person's human rights still practised in its many insidious forms in many countries. INR reviews the work of the organizations trying to help stop the perpetrators and participation of health professionals; rehabilitate the survivors; and educate health professionals and the public.

Rational use of drug-eluting stents: a comparison of different policies.

PubMed

Remmel, Marko; Hartmann, Franz; Harland, Lars C; Schunkert, Heribert; Radke, Peter W

2007-06-01

Long-term results of recent landmark trials document both benefits and risks of drug-eluting stents (DES) for coronary revascularization. Interestingly, the conclusions drawn from these data vary widely since significant differences in DES penetration rates become obvious when the utilization of this technology is compared between hospitals or even countries. Based on the recommendations of the European Society of Cardiology, the FDA as well as data derived from the BASKET-LATE study, we propose that a maximum penetration rate of 50% for DES seems appropriate at present. Analysis of the length/diameter distribution combined with the use of validated restenosis reference charts allows identification of high-risk patients regarding restenosis risk and modeling the use of DES depending on financial resources and clinical indication. Such algorithm provides the rational for preprocedural risk stratification and efficient use of resources.

Optimal allocation of conservation resources to species that may be extinct.

PubMed

Rout, Tracy M; Heinze, Dean; McCarthy, Michael A

2010-08-01

Statements of extinction will always be uncertain because of imperfect detection of species in the wild. Two errors can be made when declaring a species extinct. Extinction can be declared prematurely, with a resulting loss of protection and management intervention. Alternatively, limited conservation resources can be wasted attempting to protect a species that no longer exists. Rather than setting an arbitrary level of certainty at which to declare extinction, we argue that the decision must trade off the expected costs of both errors. Optimal decisions depend on the cost of continued intervention, the probability the species is extant, and the estimated value of management (the benefit of management times the value of the species). We illustrated our approach with three examples: the Dodo (Raphus cucullatus), the Ivory-billed Woodpecker (U.S. subspecies Campephilus principalis principalis), and the mountain pygmy-possum (Burramys parvus). The dodo was extremely unlikely to be extant, so managing and monitoring for it today would not be cost-effective unless the value of management was extremely high. The probability the Ivory-billed woodpecker is extant depended on whether recent controversial sightings were accepted. Without the recent controversial sightings, it was optimal to declare extinction of the species in 1965 at the latest. Accepting the recent controversial sightings, it was optimal to continue monitoring and managing until 2032 at the latest. The mountain pygmy-possum is currently extant, with a rapidly declining sighting rate. It was optimal to conduct as many as 66 surveys without sighting before declaring the species extinct. The probability of persistence remained high even after many surveys without sighting because it was difficult to determine whether the species was extinct or undetected. If the value of management is high enough, continued intervention can be cost-effective even if the species is likely to be extinct.

Coping with the Conflict-of-Interest Pandemic by Listening to and Doubting Everyone, Including Yourself.

PubMed

Kozlowski, Lynn T

2016-04-01

In light of the widespread existence of financial and non-financial issues that contribute to the appearance or fact of conflict of interest, it is proposed that conflict of interest should generally be assumed, no matter the source of financial support or the expressed declarations of conflicts and even with respect to one's own work. No new model is advanced for modification of peer-review processes or for elaboration of author declarations of interest. Researchers should be assessing the quality of published work as best they can and make their own decisions on the appropriate use of the work. While some apparent sources of conflict are likely more obvious and serious than others, even subtler biases can influence scientific reports. Ignoring peer-reviewed contributions because of conflict-of-interest concerns is discouraged. Listening skeptically to all sources, including yourself, is encouraged.

Dissociating response systems: erasing fear from memory.

PubMed

Soeter, Marieke; Kindt, Merel

2010-07-01

In addition to the extensive evidence in animals, we previously showed that disrupting reconsolidation by noradrenergic blockade produced amnesia for the original fear response in humans. Interestingly, the declarative memory for the fear association remained intact. These results asked for a solid replication. Moreover, given the constructive nature of memories, the intact recollection of the fear association could eventually 'rebuild' the fear memory, resulting in the spontaneous recovery of the fear response. Yet, perseverance of the amnesic effects would have substantial clinical implications, as even the most effective treatments for psychiatric disorders display high percentages of relapse. Using a differential fear conditioning procedure in humans, we replicated our previous findings by showing that administering propranolol (40mg) prior to memory reactivation eliminated the startle fear response 24h later. But most importantly, this effect persisted at one month follow-up. Notably, the propranolol manipulation not only left the declarative memory for the acquired contingency untouched, but also skin conductance discrimination. In addition, a close association between declarative knowledge and skin conductance responses was found. These findings are in line with the supposed double dissociation of fear conditioning and declarative knowledge relative to the amygdala and hippocampus in humans. They support the view that skin conductance conditioning primarily reflects contingency learning, whereas the startle response is a rather specific measure of fear. Furthermore, the results indicate the absence of a causal link between the actual knowledge of a fear association and its fear response, even though they often operate in parallel. Interventions targeting the amygdalar fear memory may be essential in specifically and persistently dampening the emotional impact of fear. From a clinical and ethical perspective, disrupting reconsolidation points to promising interventions persistently erasing fear responses from trauma memory without affecting the actual recollection.

Modulation of competing memory systems by distraction.

PubMed

Foerde, Karin; Knowlton, Barbara J; Poldrack, Russell A

2006-08-01

Different forms of learning and memory depend on functionally and anatomically separable neural circuits [Squire, L. R. (1992) Psychol. Rev. 99, 195-231]. Declarative memory relies on a medial temporal lobe system, whereas habit learning relies on the striatum [Cohen, N. J. & Eichenbaum, H. (1993) Memory, Amnesia, and the Hippocampal System (MIT Press, Cambridge, MA)]. How these systems are engaged to optimize learning and behavior is not clear. Here, we present results from functional neuroimaging showing that the presence of a demanding secondary task during learning modulates the degree to which subjects solve a problem using either declarative memory or habit learning. Dual-task conditions did not reduce accuracy but reduced the amount of declarative learning about the task. Medial temporal lobe activity was correlated with task performance and declarative knowledge after learning under single-task conditions, whereas performance was correlated with striatal activity after dual-task learning conditions. These results demonstrate a fundamental difference in these memory systems in their sensitivity to concurrent distraction. The results are consistent with the notion that declarative and habit learning compete to mediate task performance, and they suggest that the presence of distraction can bias this competition. These results have implications for learning in multitask situations, suggesting that, even if distraction does not decrease the overall level of learning, it can result in the acquisition of knowledge that can be applied less flexibly in new situations.

Analysis of the impact of a cognitive task on the posture of elderly subjects with depression compared with healthy elderly subjects.

PubMed

Casteran, Matthieu; Putot, Alain; Pfitzenmeyer, François; Thomas, Elizabeth; Manckoundia, Patrick

2016-11-01

While previous studies have demonstrated that depressive elderly subjects (DES) experience difficulties in the processing of simultaneous cognitive tasks, few have examined the coupling of cognitive tasks with seemingly 'automatic' tasks, such as standing upright. Current patient management focuses on pharmacological treatments and cognitive-behavioral therapies. Healthy elderly (HES) and non-treated DES were included. Postural sway in DES was compared with that in HES while in single-task and dual-task conditions. The single-task consisted of standing upright. For the dual-task, the subjects recalled various items from memory or counted while standing upright. Postural sway was evaluated by computing the center of pressure (CoP) area and path length. DES showed greater postural sway than HES in all conditions. The HES showed a greater CoP area in the dual-task than in the single-task conditions. In DES, the CoP area in the single-task condition was similar to that in the dual-task condition. The greater postural sway observed in DES may be a cause of a greater risk of falls. We showed that even seemingly automatic tasks, such as maintaining an upright posture, are affected by depression. These results are important for the management of DES. Copyright © 2016 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.

Contributions maternelles et paternelles au developpement des representations symboliques et categorielles des objets par les jeunes enfants (Materal and Paternal Contributions to the Development of Symbolic and Categorical Representation of Objects by Young Children).

ERIC Educational Resources Information Center

Labrell, Florence

1998-01-01

Theory and research on parent-child linguistic interactions that focus on the symbolic representation or categorization of objects are discussed, noting the role of such variables as the age of the children, linguistic context, and sex of the involved parent. During the second year of life, even if maternal and paternal games with toddlers are…

Theoretical and Experimental Methods in Hypersonic Flows (Les Methodes Theoriques et Experimentales pour l’Etude Des Ecoulements Hypersoniques)

DTIC Science & Technology

1993-04-01

PROCEEDINGS 514 OELECTE f Theoretical and A U Experimental Methods in A Hypersonic Flows (Les Methodes Th6oriques et Experimentales pour 1’Etude des...nitrogen ent for both equilibrium and non -equilibrium chemistry between the two groups . Both groups state that the boundary makes this mode even more...flowfield on control is also m?,ndatory unstable due to the necessary oblate shape of Hermes. when the experimental rebuilding is clearly poor and

L'optique spatiale au CES

NASA Astrophysics Data System (ADS)

Courtois, M.; Otrio, G.

2018-04-01

Jai le plaisir d'inaugurer cette troisieme conference ICS0'97 consacree a l'optique patialc Les techniques evoluent tres vite; l'optique et l'optoelectronique n'echappent pas a c:ene regle. Depuis Garmisch. en 1994, bien des evenements concemant ces domaines se som produits le rappellerai !es faits les plus saillants dans la premiere panie de mon expose Je donncrai ensuite un apercu des activites en cours au Cnes et je tenninerai en parlant du futur quelles sont les technologies emergentes et quels projets peuvent en decouler ?

Litigation involving DES.

PubMed

Rheingold, P D

1976-01-01

Focus is on the diethylstilbestrol (DES) litigation which has resulted from the 1971 discovery that this synthetic estrogen can cause cancer in the daughters of women who used the drug during pregnancy in an effort to prevent threatened abortion. Possibly 100 suits are pending at this time in which DES daughters claim injuries. In most of these vaginal or cervical cancer has appeared -- with or without a hysterectomy having been performed. Several women died from cancer. The fact that the use of DES occurred many years ago is the legal hurdle most troublesome to lawyers. The average women coming to a lawyer's office today has a mother who used some form of DES, perhaps in 1955. Few drugstores have records today of the prescriptions which they filled 20 years ago. It has been estimated that over the 1950-1970 period more than 200 different companies manufactured or "tabletized" under their own name DES plus a variety of similar synthetic estrogens promoted for the prevention of threatened abortion. A further hurdle caused by the passage of time is that even the records of the physicians are frequently lost. A final problem created by the age of the cases is statute of limitations. If the actual manufacturer of the DES cannot be identified, this is generally the end of the lawyer's interest in the case. The chance of the plaintiff winning may be increased if the action against all the manufacturers is a class action. Most of the pending DES suits are against the manufacturer and not against the doctor. Thus far no DES case has been tried to completion. Several have been settled by the manufacturers on the eve of the trial, generally for less than the full sum that a cancer victim would expect to receive.

Strategic Insights, Volume 5, Issue 2, February 2006. Ecuador: The Continuing Challenge of Democratic Consolidation and Civil-Military Relations

DTIC Science & Technology

2006-02-01

declare the presidency vacant on charges that the president had “abandoned his post ” even though Gutierrez was in the presidential palace issuing...institutions that continued functioning, the Electoral Tribunal, found that it was not constitutional. Even in early 2006, they are still working on...Stepan, Problems of Democratic Transition and Consolidation: Southern Europe, South America, and Post -Communist Europe (Baltimore: Johns Hopkins

Bi-frontal transcranial alternating current stimulation in the ripple range reduced overnight forgetting.

PubMed

Ambrus, Géza Gergely; Pisoni, Alberto; Primaßin, Annika; Turi, Zsolt; Paulus, Walter; Antal, Andrea

2015-01-01

High frequency oscillations in the hippocampal structures recorded during sleep have been proved to be essential for long-term episodic memory consolidation in both animals and in humans. The aim of this study was to test if transcranial Alternating Current Stimulation (tACS) of the dorsolateral prefrontal cortex (DLPFC) in the hippocampal ripple range, applied bi-frontally during encoding, could modulate declarative memory performance, measured immediately after encoding, and after a night's sleep. An associative word-pair learning test was used. During an evening encoding phase, participants received 1 mA 140 Hz tACS or sham stimulation over both DLPFCs for 10 min while being presented twice with a list of word-pairs. Cued recall performance was investigated 10 min after training and the morning following the training session. Forgetting from evening to morning was observed in the sham condition, but not in the 140 Hz stimulation condition. 140 Hz tACS during encoding may have an effect on the consolidation of declarative material.

Delivery of large biopharmaceuticals from cardiovascular stents: a review

PubMed Central

Takahashi, Hironobu; Letourneur, Didier; Grainger, David W.

2008-01-01

This review focuses on the new and emerging large-molecule bioactive agents delivered from stent surfaces in drug-eluting stents (DES) to inhibit vascular restenosis in the context of interventional cardiology. New therapeutic agents representing proteins, nucleic acids (small interfering RNAs and large DNA plasmids), viral delivery vectors and even engineered cell therapies require specific delivery designs distinct from traditional smaller molecule approaches on DES. While small molecules are currently the clinical standard for coronary stenting, extension of the DES to other lesion types, peripheral vasculature and non-vasculature therapies will seek to deliver an increasingly sophisticated armada of drug types. This review describes many of the larger molecule and biopharmaceutical approaches reported recently for stent-based delivery with the challenges associated with formulating and delivering these drug classes compared to the current small molecule drugs. It also includes perspectives on possible future applications that may improve safety and efficacy and facilitate diversification of the DES to other clinical applications. PMID:17929968

Targeted stent use in clinical practice based on evidence from the Basel Stent Cost Effectiveness Trial (BASKET).

PubMed

Brunner-La Rocca, Hans-Peter; Kaiser, Christoph; Pfisterer, Matthias

2007-03-01

It is unknown which patients benefit most from drug-eluting stents (DES) against bare-metal stents (BMS) in a long-term clinical outcome. To address this question, data from 826 consecutive patients with angioplasty, randomized 2:1 to DES vs. BMS, with an 18-month follow-up for cardiac death/myocardial infarction (MI) and non-MI-related target-vessel revascularization (TVR) were analysed for interactions between stent type and patient/vessel characteristics predicting events. Rates of 18-month TVRs were lower with DES vs. BMS use (7.5 vs. 11.6%, P = 0.05), but similar for both stents regarding cardiac death/MI (DES, 8.4%; BMS, 7.5%; P = 0.70). Significant interactions between stent type and two multivariable event predictors were identified: small stents (<3.0 mm) and bypass graft stenting. In these patient groups together (n = 268, 32%), DES reduced non-MI-related TVR (HR = 0.44; P = 0.02) and cardiac death/MI (HR = 0.44; P = 0.04), whereas in the other 558 patients (68%) TVR rate was similar (HR = 0.75; P = 0.38) and cardiac death/MI rate increased after DES (HR = 2.07; P = 0.05). Patients with angioplasty of small vessels or bypass grafts seem to benefit from DES use, in long-term outcome, in contrast to patients with large native vessel stenting where there might even be late harm. Still, this hypothesis needs to be tested prospectively.

[Master course in biomedical engineering].

PubMed

Jobbágy, Akos; Benyó, Zoltán; Monos, Emil

2009-11-22

The Bologna Declaration aims at harmonizing the European higher education structure. In accordance with the Declaration, biomedical engineering will be offered as a master (MSc) course also in Hungary, from year 2009. Since 1995 biomedical engineering course has been held in cooperation of three universities: Semmelweis University, Budapest Veterinary University, and Budapest University of Technology and Economics. One of the latter's faculties, Faculty of Electrical Engineering and Informatics, has been responsible for the course. Students could start their biomedical engineering studies - usually in parallel with their first degree course - after they collected at least 180 ECTS credits. Consequently, the biomedical engineering course could have been considered as a master course even before the Bologna Declaration. Students had to collect 130 ECTS credits during the six-semester course. This is equivalent to four-semester full-time studies, because during the first three semesters the curriculum required to gain only one third of the usual ECTS credits. The paper gives a survey on the new biomedical engineering master course, briefly summing up also the subjects in the curriculum.

Resistance of Aëdes aegypti to certain chlorinated hydrocarbon and organo-phosphorus insecticides in Puerto Rico*

PubMed Central

Fox, Irving

1961-01-01

Failure to control Aëdes aegypti in Puerto Rico has suggested resistance to the insecticides, particularly DDT. A laboratory colony (named Isla Verde strain) was established from material obtained near the International Airport. This strain proved highly resistant to DDT and dieldrin as well as various other insecticides. The scientific and practical significance of this is far-reaching. Heretofore, it was thought that populations of Aëdes aegypti could be resistant to the DDT group of insecticides or to the dieldrin group but not to both, and that one type of resistance involved biochemical, toxicological and genetic characteristics different from the other. This theory must now be modified or even abandoned. From the practical point of view, it is clear that the continued use of DDT or dieldrin for Aëdes aegypti control in Puerto Rico is questionable, for it is not wise to attempt to overcome high resistance by increasing the concentration or rate of application. Further, the situation demonstrated for Puerto Rico may also obtain in other islands of the Caribbean where Aëdes aegypti is known to be DDT-resistant. PMID:13701099

Impact of stent diameter and length on in-stent restenosis after DES vs BMS implantation in patients needing large coronary stents-A clinical and health-economic evaluation.

PubMed

Zbinden, Rainer; von Felten, Stefanie; Wein, Bastian; Tueller, David; Kurz, David J; Reho, Ivano; Galatius, Soren; Alber, Hannes; Conen, David; Pfisterer, Matthias; Kaiser, Christoph; Eberli, Franz R

2017-02-01

The British National Institute of Clinical Excellence (NICE) guidelines recommend to use drug-eluting stents (DES) instead of bare-metal stents (BMS) only in lesions >15 mm in length or in vessels <3 mm in diameter. We analyzed the impact of stent length and stent diameter on in-stent restenosis (ISR) in the BASKET-PROVE study population and evaluated the cost-effectiveness of DES compared to BMS. The BASKET-PROVE trial compared DES vs BMS in large coronary arteries (≥3 mm). We calculated incremental cost-effectiveness ratios (ICERs) and cost-effectiveness acceptability curves with regard to quality-adjusted life years (QALYs) gained and target lesion revascularizations (TLRs) avoided. A total of 2278 patients were included in the analysis. A total of 74 ISR in 63 patients were observed. In-stent restenosis was significantly more frequent in segments treated with a BMS compared to segments treated with a DES (5.4% vs 0.76%; P<.001). The benefit of a DES compared to a BMS regarding ISR was consistent among the subgroups of stent length >15 mm and ≤15 mm, respectively. With the use of DES in short lesions, there was only a minimal gain of 0.005 in QALYs. At a threshold of 10 000 CHF per TLR avoided, DES had a high probability of being cost-effective. In the BASKET-PROVE study population, the strongest predictor of ISR is the use of a BMS, even in patients in need of stents ≥3.0 mm and ≤15 mm lesion length and DES were cost-effective. This should prompt the NICE to reevaluate its recommendation to use DES instead of BMS only in vessels <3.0 mm and lesions >15 mm length. © 2016 John Wiley & Sons Ltd.

14 CFR 399.3 - Statements in other Board documents.

Code of Federal Regulations, 2011 CFR

2011-01-01

... Section 399.3 Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF TRANSPORTATION (AVIATION..., order, certificate, permit, exemption, or waiver shall be considered a statement of policy within the meaning of this part, even though such statements may constitute a precedent in future cases or declare...

14 CFR 399.3 - Statements in other Board documents.

Code of Federal Regulations, 2014 CFR

2014-01-01

... Section 399.3 Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF TRANSPORTATION (AVIATION..., order, certificate, permit, exemption, or waiver shall be considered a statement of policy within the meaning of this part, even though such statements may constitute a precedent in future cases or declare...

14 CFR 399.3 - Statements in other Board documents.

Code of Federal Regulations, 2012 CFR

2012-01-01

... Section 399.3 Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF TRANSPORTATION (AVIATION..., order, certificate, permit, exemption, or waiver shall be considered a statement of policy within the meaning of this part, even though such statements may constitute a precedent in future cases or declare...

14 CFR 399.3 - Statements in other Board documents.

Code of Federal Regulations, 2013 CFR

2013-01-01

... Section 399.3 Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF TRANSPORTATION (AVIATION..., order, certificate, permit, exemption, or waiver shall be considered a statement of policy within the meaning of this part, even though such statements may constitute a precedent in future cases or declare...

14 CFR 399.3 - Statements in other Board documents.

Code of Federal Regulations, 2010 CFR

2010-01-01

... Section 399.3 Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF TRANSPORTATION (AVIATION..., order, certificate, permit, exemption, or waiver shall be considered a statement of policy within the meaning of this part, even though such statements may constitute a precedent in future cases or declare...

Re-engineering Engineering Education

ERIC Educational Resources Information Center

Gordon, Bernard M.; Silevitch, Michael B.

2009-01-01

In 2005, leaders gathered by the National Association of Manufacturers declared yet another "STEM" emergency. In the face of global competition, they argued, the number of bachelor's degrees awarded annually to U.S. students in science, math and engineering must double by 2015. In fact, the need for STEM talent is even more critical…

Current methodology to assess bioequivalence of levothyroxine sodium products is inadequate.

PubMed

Blakesley, Vicky A

2005-03-30

Levothyroxine sodium is a drug with a narrow therapeutic index for which an individual patient must have his or her dose carefully titrated to achieve the necessary therapeutic effect. In addition, exogenous levothyroxine cannot be distinguished from the endogenously produced hormone. Since 2004, generic formulations have been approved for the most frequently prescribed brands of levothyroxine sodium. This review examines the methodology and statistical acceptance criteria and summarizes findings of a previously published relative bioavailability study that brings into question the use of standard criteria to assess bioequivalence of levothyroxine sodium. The key findings reviewed were the following: (1) in the absence of baseline correction for endogenous T4 levels, products that differed by as much as 25% to 33% would be declared bioequivalent; (2) the use of baseline correction reduced the likelihood of declaring products bioequivalent when they actually differed by 25% to 33%; (3) even with baseline correction, products that differed by 12.5% would be declared bioequivalent; and (4) there was evidence of significant carryover from one dosing period to the next even with washout periods of up to 53 days. In conclusion, the current recommended methodology in the United States to assess bioequivalence for levothyroxine sodium products is inadequate to differentiate products that differ by 12.5%, a clinically relevant difference. Recommendations are made for modifications to the criteria that could improve the likelihood that products that differ by a clinically significant amount in their bioavailability would not be accepted as bioequivalent.

Ecoulement et mise en structure de suspensions macroscopiques

NASA Astrophysics Data System (ADS)

Petit, L.

In this review, we report the various experimental studies performed on suspensions of solid particules in liquids, and concerning the rheological behaviour of such systems and the ordering of particules under the applied velocity fields. The number of materials which are flowing suspensions (reagents in chemical engineering, paints while spreading, blood flow, muds in oil reservoir) gave rise to a number of experimental studies, especially in the last twenty years. The results show a wide variety of behaviour, even for systems of intermediate concentration. In addition, even for identical systems, the results depend of the type of flow. Then, it is clear that, in addition of the standard parameters which are to be taken into account, it is necessary to consider the type of flow the suspension is submitted to. The flow influences the spatial distribution of the particules, leading to their ordering or migration. These ordering or motions influence the flow, and then, the rheological behaviour of the whole system. So, there is a feedback mechanism from the ordering to the flow, which explains the experimental observations. Nous reportons dans cette revue les différentes études expérimentales réalisées sur les suspensions de particules solides dans un liquide et qui concernent le comportement rhéologique de ces systèmes ainsi que les mouvements des particules sous l'effet des champs de vitesse imposés. Ces mouvements peuvent conduire soit à des mises en structure, ou encore à des migrations des particules. L'importance du nombre de matériaux qui se présentent sous forme de suspension et qui sont mis en écoulement (réactif en génie chimique, peintures lors de leur mise en place, écoulement sanguin, boues dans les forages pétroliers,...) a motivé un grand nombre de travaux expérimentaux plus fondamentaux sur le sujet, particulièrement dans les vingt dernières années. Les résultats correspondants montrent une très grande diversité des comportements même pour les systèmes moyennement concentrés. Bien plus, pour des systèmes identiques, les résultats dépendent du type d'écoulement imposé. Ceci montre clairement, qu'à côté des facteurs standards qui sont à prendre en compte pour caractériser le comportement de tels systèmes (concentration de la phase solide, taille des particules, interactions entre particules, effets de diffusion,...), il est nécessaire de tenir compte de la nature de l'écoulement auquel est soumise la suspension. Cet écoulement modifie la distribution spatiale des particules, soit directement, soit par l'intermédiaire de différents mécanismes tels que écoulements secondaires, diffusion. Ces effets se traduisent par une mise en ordre des particules, ou bien à des mouvements de migration. Les structures ou les mouvements ainsi créés agissent à leur tour sur les propriétés de l'écoulement, et de là, sur le comportement rhéologique de l'ensemble du système. Il existe ainsi un mécanisme de rétroaction de la structure sur l'écoulement qui permet d'expliquer les comportements observés expérimentalement.

Le transfert de connaissances entre les mathematiques et les sciences. Une etude exploratoire aupres d'eleves de 4e secondaire

NASA Astrophysics Data System (ADS)

Samson, Ghislain

2003-06-01

Au moment ou dans plusieurs pays on travaille a refondre les programmes d'etudes, tant au primaire qu'au secondaire, l'interet pour le transfert renait. Un des concepts fondamentaux en apprentissage consiste en l'habilete a reutiliser de facon consciente et efficace un acquis d'une situation a une autre situation. Cette recherche emane de preoccupations professionnelles au moment ou le chercheur etait enseignant au secondaire. Au cours de ces annees, il lui a ete possible de constater que plusieurs eleves percevaient difficilement les liens presents entre les disciplines mathematiques et scientifiques. Des travaux en psychologie cognitive et plus particulierement selon une perspective du traitement de l'information ont servi de cadre de reference pour evaluer et analyser les capacites de transfert aupres d'eleves de 4e secondaire. Ce cadre de reference permet de formuler le principal objectif qui est de mieux comprendre le processus de transfert chez des eleves en situation de resolution de problemes scientifiques. Cette these s'interesse donc au transfert en tant que phenomene important du processus d'apprentissage au sens de l'integration. La methode de recherche choisie, de nature qualitative, est principalement axee sur l'evaluation de la capacite a transferer des connaissances lors d'une epreuve et d'un entretien. Pour evaluer ce potentiel de transfert, nous avons elabore deux outils: une epreuve en mathematiques et en sciences et un guide d'entretien. Pour la passation de l'epreuve, le chercheur a pu compter sur la collaboration de 130 sujets provenant de deux ecoles. L'entretien complete la prise de donnees avec 13 sujets ayant accepte de poursuivre l'etude. Les donnees recueillies par ces instruments font ensuite l'objet d'une analyse de contenu. En premier lieu, les verbatims de l'epreuve et de l'entretien ont ete transcrits, puis codifies. La correction des reponses fournies pour les problemes resolus s'est faite a partir d'une grille d'analyse qualitative et adaptee de la litterature (Thouin, 1995). Une seconde serie d'analyses permettant de categoriser les reponses selon la typologie des connaissances declaratives, procedurales et conditionnelles complete la prise de donnees. Nos resultats indiquent que les sujets sont tres influences par des elements de surface, principalement lorsqu'il s'agit de problemes auxquels ils ne sont pas habitues. En l'absence de connaissances de base, plusieurs sujets vont tendre vers des propositions de solution "pratico-pratique" provenant de leur vecu: cela nous apparait d'importance d'un point de vue didactique et en matiere de transfert. Lors des entretiens realises un mois plus tard, les sujets ont eprouve de la difficulte a se rappeler le contenu de l'epreuve. Et lorsqu'il y avait un rappel, celui-ci etait superficiel et surtout axe sur le contenu ou le contexte d'un probleme. La plupart des sujets ne pouvait nommer que deux ou trois elements (des problemes en mathematiques, en sciences physiques, le probleme de la fenetre, le probleme du laser, etc.). Nos resultats confirment ce que plusieurs chercheurs (Julo, 1995, Jonnaert et Vander Borght, 1999; Richard et al., 1990) qui s'interessent aux questions de l'apprentissage admettent aujourd'hui: l'eleve ne travaille jamais sur la situation proposee par l'enseignant, mais bien sur la representation qu'il s'en est construite. Au plan methodologique, cette recherche est interessante par la variete des sources de collecte de donnees utilisees, par l'application d'outils methodologiques et d'analyses originaux tires de la recherche et de la pratique. Du cote theorique, il resulte de cette etude une meilleure comprehension du processus de transfert des connaissances mathematiques vers les sciences physiques. Finalement, aux plans didactique et pedagogique, cette recherche alimente la reflexion sur l'apprentissage et l'enseignement des sciences au secondaire. Elle fait ressortir que les mathematiques sont importantes dans la mobilisation de certaines connaissances scientifiques et que l'enseignant peut et devrait jouer un role pour favoriser le transfert.

Influence of electronegativity on the electronic structures and stabilities of microclusters of carbides MC_n (M : transition, rare-earth or normal element, n < 10)

NASA Astrophysics Data System (ADS)

Leleyter, M.

1991-10-01

MC_n, clusters (n < 10) produced from carbides by various experimental techniques (SIMS, SSMS, LAMMA, Knudsen effusion, etc.) show strong alternations in their emission intensities I(MC^+_n) according to the parity of the carbon atom number n. Maxima take place for odd n (“odd" alternations) if M = H, F, Cl or Fe, Ni, Rh, Ir, Pt or for even n (“even" alternations) if M = B, Si, Ba, Ge or Sc, Ti, V, Cr, Y, Zr, La, Ce, W, Th, U or even the ions exist only for even n (Nd, Dy, Ho, Er). Moreover, only CO, C_3O, CN and C_3N are known for O and N. Such phenomena are due to the stability properties of the clusters themselves (“correspondence rule") and can be interpreted with the Pitzer and Clementi model (sp hybridization in Hückel approximation): the clusters are assumed to be linear chains of “cumulene" type :C=C=..C=C=M and the alternations in the relative stabilities of these chains are mainly due to the fact that the HOMO (highest occupied molecular orbital) of the clusters lies in a double degenerate π level band. Now HOMO may be either full or half-filled, and an aggregate with a complete (or almost complete) HOMO is more stable than an aggregate with a half-filled HOMO. Consequently, the number of π electrons is governing the parity effect in the stability alternations. However, this number is depending on the number of σ electrons of the chain and besides, for the transition or rare-earth metals, on the positions of the dσ and degenerate dδ levels due to the M atom, which are governed by Pauling's electronegativity (EN) of atom M. For transition or lanthanide metals, the alternations are “even" if EN le 1.7 (deficient d electron-elements: columns IIIA to VIIA; empty dσ and δ levels) or “odd" in the reverse case (rich d electron elements: column VIIIA bonding dσ and δ levels). For normal elements, the limit of EN seems to be the EN of C (2.5) and the alternations are “even" if EN le 2.5 or “odd" in the other case. Thus it is possible to infer a likely electronic configuration of the MC_n clusters and 2 tables give the compared electronic structures of these clusters for normal or transition elements. Such a kind of structure is only able to explain the parity effect origin of the MC_n clusters and even enable to foreknow for transition or rare-earth metal carbides which are not studied yet if the alternations will be “even" (EN le 1.7) or “odd". Les agrégats MC_n obtenus à partir de carbures par diverses méthodes expérimentales (SIMS, SSMS, vaporisation laser, effusion de Knudsen à haute température, etc.) présentent des alternances dans leurs intensités d'émission I(MC^+_n) avec maximums pour n impair si M = H, F, CI ou Fe, Ni, Rh, Ir, Pt ou au contraire pour n pair si M = B, Si, Ba, Ge ou Sc, Ti, V, Cr, Y, Zr, La, Ce, W, Th, U ou même n'existent que pour n pair (Nd, Dy, Ho, Er). D'autre part, seuls sont connus CO, C_3O, CN et C_3N pour l'oxygène et l'azote. Ces phénomènes sont interprétés tout d'abord à l'aide de la règle bien connue de correspondance qui relie de fortes (resp. faibles) intensités ou fréquences d'émissions d'ions MC^+_n à de fortes (resp. faibles) stabilités des amas correspondants. En second lieu, ces résultats s'expliquent dans le cadre du modèle de Pitzer et Clementi (hybridation sp en théorie de Hückel) corroboré par des calculs CNDO: on suppose que les amas MC^+_n sont des chaînes linéaires C^+_n portant un atome d'impureté M en bout de chaîne. Dans ces conditions, les alternances de stabilités relatives des MC_n proviennent de ce que l'orbitale moléculaire la plus élevée (“ HOMO ”) se trouve dans une bande niveaux π doublement dégénérés et qu'à une orbitale π complète (4 électrons) correspond une plus forte stabilité de l'amas que si l'orbitale est incomplète. Or le nombre d'électrons π d'une chaîne MC_n est gouverné par le nombre de niveaux σ liants et en outre pour les éléments de transition ou de terres rares, par la position du niveau dσ et celle du niveau δ dégénérés dus à la présence de l'atome M. Dans le cas des éléments normaux, si M est plus électronégatif que C (EN = 2,5), l'orbitale sσ_M sera liante (2 électrons) alors qu'elle sera antiliante (vide) dans le cas contraire, et entraînera donc une différence de 2 électrons σ ou π, donc un changement de sens des alternances. Le cas spécial de H peut aussi s'expliquer dans ce cadre. Les éléments de transition pour leur part, se scindent en 2 groupes suivant que leur électronégativité EN est supérieure à 1,7 (éléments ayant beaucoup d'électrons d : colonne VIIIA ; niveaux δ et dσ liants) ou non (peu d'électrons d : colonnes IIIA et terres rares à VIIA ; niveaux δ et dσ vides). Nous donnons deux tableaux récapitulant la structure comparée des niveaux des agrégats MC_n pour les éléments normaux ou de transition. Ce type de structure peut seul expliquer l'origine des alternances des amas MC_n et permet même de prévoir pour des carbures de transition ou de terres rares non encore étudiés, si les alternances seront “ paires ” (EN le 1,7 ) ou “ impaires ” (EN > 1,7).

Air Vehicle Mission Control and Management, The Guidance and Control Panel Symposium (53rd) Held in Amsterdam, The Netherlands on 22-25 October 1991 ((La Gestion et le Controle des Missions des Vehicules Aeriens)

DTIC Science & Technology

1992-03-01

will address this point later, for an even larger proportion of weapon systems. Again a variation in operation that require IV. FUTURE ENVIRONMENTS FOR...the proportion by which sight angle are calculated similarly to the Mach number differs from the instantaneous Paladin aircraft parameters (equations 1...CONCLUSIONS SHORTFALL The proposition that teamworK should be a high- level design driver poses a radical departure from FIGURE 5 - Audit Component Proportions

a-Band Oscillations in Intracellular Membrane Potentials of Dentate Gyrus Neurons in Awake Rodents

ERIC Educational Resources Information Center

Anderson, Ross W.; Strowbridge, Ben W.

2014-01-01

The hippocampus and dentate gyrus play critical roles in processing declarative memories and spatial information. Dentate granule cells, the first relay in the trisynaptic circuit through the hippocampus, exhibit low spontaneous firing rates even during locomotion. Using intracellular recordings from dentate neurons in awake mice operating a…

Shirley Campbell's Ideology of Historiographic Legitimation

ERIC Educational Resources Information Center

Ramsay, Paulette A.

2014-01-01

This article examines a number of poems in which Shirley Campbell challenges the myth of historical objectivity by suggesting that the history of African diasporic peoples and societies has been obliterated in Europe's agenda to relegate them to positions of subservience and deny even their very existence. The poetic voice declares that…

Academic Rights 101: An Introduction in a Malaysian Context

ERIC Educational Resources Information Center

Mahat, Rosli H.; Shah, Mohd Hazim

2013-01-01

The concept of academic rights is greatly misunderstood, even among some university academics. This paper provides a summary of the historical development of the academic rights from the Roman to the modern era. Many documents and declarations advocating academic rights have been produced, and this paper presents a discussion of the recent…

Put Power into Your Presentations: Using Presentation Software Effectively

ERIC Educational Resources Information Center

Safransky, Robert J.; Burmeister, Marsha L.

2009-01-01

Microsoft PowerPoint, Apple Keynote, and OpenOffice Impress are relatively common tools in the classroom and in the boardroom these days. What makes presentation software so popular? As the Chinese proverb declares, a picture is worth a thousand words. People like visual presentations. Presentation software can make even a dull subject come to…

Impaired event memory and recollection in a case of developmental amnesia.

PubMed

Rosenbaum, R S; Carson, N; Abraham, N; Bowles, B; Kwan, D; Köhler, S; Svoboda, E; Levine, B; Richards, B

2011-10-01

A current debate in the literature is whether all declarative memories and associated memory processes rely on the same neural substrate. Here, we show that H.C., a developmental amnesic person with selective bilateral hippocampal volume loss, has a mild deficit in personal episodic memory, and a more pronounced deficit in public event memory; semantic memory for personal and general knowledge was unimpaired. This was accompanied by a subtle difference in impairment between recollection and familiarity on lab-based tests of recognition memory. Strikingly, H.C.'s recognition did not benefit from a levels-of-processing manipulation. Thus, not all types of declarative memory and related processes can exist independently of the hippocampus even if it is damaged early in life.

Perceptions of conflict of interest: surgeons, internists, and learners compared.

PubMed

de Gara, Christopher J; Rennick, Kim C; Hanson, John

2013-05-01

Making a conflict of interest declaration is now mandatory at continuing medical education CME accredited events. However, these declarations tend to be largely perfunctory. This study sought to better understand physician perceptions surrounding conflict of interest. The same PowerPoint (Microsoft, Canada) presentation (http://www.youtube.com/watch?v=mQSOvch7Yg0&feature=g-upl) was delivered at multiple University of Alberta and Royal College CME-accredited events to surgeons, internists, and learners. After each talk, the audience was invited to complete an anonymous, pretested, and standardized 5-point Likert scale (strongly disagree to strongly agree) questionnaire. A total of 136 surveys were analyzed from 31 surgeons, 49 internists, and 56 learners. In response to the question regarding whether by simply making a declaration, the speaker had provided adequate proof of any conflicts of interest, 71% of surgeons thought so, whereas only 35% of internists and 39% of learners agreed or strongly agreed (P = .004). Further probing this theme, the audience was asked whether a speaker must declare fees or monies received from industry for consulting, speaking, and research support. Once again there was a variance of opinion, with only 43% of surgeons agreeing or strongly agreeing with this statement; yet, 80% of internists and 71% of learners felt that such a declaration was necessary (P = .013). On the topic of believability (a speaker declaration makes him or her and the presentation more credible), the 3 groups were less polarized: 50% of surgeons, 41% of internists, and 52% of learners (P = .2) felt that this was the case. Although two thirds of surgeons (68%) and learners (66%) and nearly all internists (84%) felt that industry-sponsored research was biased, these differences were not significant (P = .2). Even when they are completely open and honest, conflict of interest declarations do not negate the biases inherent in a speaker's talk or research when it is industry sponsored. The larger issue is how best to manage these conflicts. Copyright © 2013 Elsevier Inc. All rights reserved.

Dissociation in the laboratory: a comparison of strategies.

PubMed

Leonard, K N; Telch, M J; Harrington, P J

1999-01-01

Several methods for inducing dissociation in the laboratory were examined in a sample of 78 undergraduate students. Participants scoring high or low on the Dissociative Experiences Scale participated in three dissociation challenge conditions: (a) dot-staring task, (b) administration of pulsed photic and audio stimulation and (c) stimulus deprivation. Participants recorded their dissociative experiences both before and after each of the three challenge conditions. Across conditions, high DES participants reported significantly more dissociative sensations than low DES participants, even after controlling for pre-challenge dissociation. Moreover, regardless of DES status, pulsed photo and audio stimulation produced the greatest level of dissociative symptoms. The findings suggest that the induction of dissociative symptoms in a nonclinical sample is easily accomplished in the laboratory and that those who report more dissociative symptoms in their day-to-day life exhibit more pronounced dissociative symptoms when undergoing dissociative challenge in the laboratory. Implications for the study and treatment of dissociative symptoms are discussed.

Safety and efficacy of the next generation Resolute Onyx zotarolimus-eluting stent: Primary outcome of the RESOLUTE ONYX core trial.

PubMed

Price, Matthew J; Shlofmitz, Richard A; Spriggs, Douglas J; Haldis, Thomas A; Myers, Paul; Popma Almonacid, Alexandra; Maehara, Akiko; Dauler, Michelle; Peng, Yun; Mehran, Roxana

2017-09-23

To assess the safety and efficacy of the novel Resolute (R-) Onyx drug-eluting stent (DES). The R-Onyx DES consists of a composite wire with an outer shell of cobalt chromium alloy and a platinum-iridium inner core to enhance radiopacity, with thinner, swaged struts and modified stent geometry compared with the predicate Resolute DES, resulting in a slightly lower total drug load in most sizes. This was a prospective, single-arm non-inferiority trial compared with a historical control. Patients with stable angina/ischemia and up to 2 de novo target lesions ≤35 mm long with reference vessel diameter (RVD) of 2.25-4.2 mm were enrolled. The primary endpoint was late lumen loss at 8-month follow-up. Propensity-score adjusted outcomes from the single-arm RESOLUTE-US trial served as the control. Seventy-five patients (85 lesions) were enrolled. Mean patient age was 66 ± 9 years, 73% were male, and 32% had diabetes. Mean lesion length was 14.28 ± 6.68 mm, mean RVD was 2.57 ± 0.48 mm, and 86% of lesions were class B2/C. In-stent late lumen loss at 8 months was 0.24 ± 0.39 mm with R-Onyx DES compared with 0.36 ± 0.52 mm with Resolute DES (P < 0.001 for noninferiority, P = 0.029 for superiority). At 8 months, clinically driven target lesion revascularization occurred in 3 patients (4.0%) and target lesion failure occurred in 5 patients (6.7%). In-stent late lumen loss is non-inferior, and appears to be superior, with the thin-strut novel composite wire R-Onyx DES compared with Resolute DES. Continued evolution of stent design can improve angiographic outcomes in complex lesions, even in the current era of next-generation DES. © 2017 Wiley Periodicals, Inc.

The origin of dwarf early-type galaxies

NASA Astrophysics Data System (ADS)

Toloba, E.

2013-05-01

We have conducted a spectrophotometric study of dwarf early-type galaxies (dEs) in the Virgo cluster and in regions of lower density. We have found that these galaxies show many properties in common with late-type galaxies but not with more massive early-types (E/S0). The properties of the dEs in Virgo show gradients within the cluster. dEs in the outer parts of the Virgo cluster are kinematically supported by rotation, while those in the center are supported by the random motions of their stars (i.e. pressure supported). The rotationally supported dEs have disky isophotes and faint underlying spiral/irregular substructures, they also show younger ages than those pressure supported, which have boxy isophotes and are smooth and regular, without any substructure. We compare the position of these dEs with massive early-type galaxies in the Faber-Jackson and Fundamental Plane relations, and we find that, although there is no difference between the position of rotationally and pressure supported dEs, both deviate from the relations of massive early-type galaxies in the direction of dwarf spheroidal systems (dSphs). We have used their offset with respect to the Fundamental Plane of E/S0 galaxies to estimate their dark matter fraction. All the properties studied in this work agree with a ram pressure stripping scenario, where late-type galaxies infall into the cluster, their interaction with the intergalactic medium blows away their gas and, as a result, they are quenched in a small amount of time. However, those dEs in the center of the cluster seem to have been fully transformed leaving no trace of their possible spiral origin, thus, if that is the case, they must have experienced a more violent mechanism in combination with ram pressure stripping, the open problem is that even galaxy harassment does not fully explain the observed properties for the pressure supported dEs in the center of the Virgo cluster.

Short Sleep Makes Declarative Memories Vulnerable to Stress in Humans

PubMed Central

Cedernaes, Jonathan; Rångtell, Frida H.; Axelsson, Emil K.; Yeganeh, Adine; Vogel, Heike; Broman, Jan-Erik; Dickson, Suzanne L.; Schiöth, Helgi B.; Benedict, Christian

2015-01-01

Study Objective: This study sought to investigate the role of nocturnal sleep duration for the retrieval of oversleep consolidated memories, both prior to and after being cognitively stressed for ∼30 minutes the next morning. Design: Participants learned object locations (declarative memory task comprising 15 card pairs) and a finger tapping sequence (procedural memory task comprising 5 digits) in the evening. After learning, participants either had a sleep opportunity of 8 hours (between ∼23:00 and ∼07:00, full sleep condition) or they could sleep between ∼03:00 and ∼07:00 (short sleep condition). Retrieval of both memory tasks was tested in the morning after each sleep condition, both before (∼08:30) and after being stressed (∼09:50). Setting: Sleep laboratory. Participants: 15 healthy young men. Results: The analyses demonstrated that oversleep memory changes did not differ between sleep conditions. However, in their short sleep condition, following stress hallmarked by increased subjective stress feelings, the men were unable to maintain their pre-stress performance on the declarative memory task, whereas their performance on the procedural memory task remained unchanged. While men felt comparably subjectively stressed by the stress intervention, overall no differences between pre- and post-stress recalls were observed following a full night of sleep. Conclusions: The findings suggest that 8-h sleep duration, within the range recommended by the US National Sleep Foundation, may not only help consolidate newly learned procedural and declarative memories, but also ensure full access to both during periods of subjective stress. Citation: Cedernaes J, Rångtell FH, Axelsson EK, Yeganeh A, Vogel H, Broman JE, Dickson SL, Schiöth HB, Benedict C. Short sleep makes declarative memories vulnerable to stress in humans. SLEEP 2015;38(12):1861–1868. PMID:26158890

"Fresh" Thoughts on Studying Sexual Assault

ERIC Educational Resources Information Center

Norris, Jeanette

2011-01-01

When the author started graduate school in the late 1970s, she was drawn to studying sexual assault. She had been a declared feminist since high school as the Women's Movement even reached the coal region of eastern Pennsylvania! Attending college in New York City, with its myriad opportunities for more exposure to what feminists were up to, made…

Differentiation, Development, (Dis)Integration: Education in Nepal's "People's War"

ERIC Educational Resources Information Center

Shields, Robin; Rappleye, Jeremy

2008-01-01

A violent conflict between Maoist insurgents and the national government has engulfed Nepal for most of the last decade, a situation that has been complicated by deep-seated instability at the highest levels of the government itself. Even with the declaration of a ceasefire in 2006, violence endures in pockets of lawless banditry and unrest at the…

A Project Management Perspective on Student's Declarative Commitments to Goals Established within Asynchronous Communication

ERIC Educational Resources Information Center

Chiocchio, F.; Lafreniere, A.

2009-01-01

Teamwork and technology, even as people are seeing their increased use in organizations, are becoming important components of problem-based learning in academic settings. Yet, fostering computer-assisted teamwork is complex and time consuming. Knowing how and when to intervene would prove useful. This study draws from the field of project…

Exploring the Legacy of Magna Carta with Students through Historic Images

ERIC Educational Resources Information Center

Wesson, Stephen

2014-01-01

Every iconic document owes a debt to a document that came before it, just as its creators were influenced by the thinkers and writers who came before them. The Declaration of Independence, U.S. Constitution, and Bill of Rights were revolutionary works, and have become powerful symbols of democracy worldwide. Behind them stands an even older…

A Decade of Change in Mainstream Education for Children with Intellectual Disabilities in the Republic of Ireland

ERIC Educational Resources Information Center

McConkey, Roy; Kelly, Caraoisa; Craig, Sarah; Shevlin, Michael

2016-01-01

Inclusive rather than segregated schooling has been advocated in several significant international declarations during the past two decades. Even so children with significant intellectual disabilities are at greater risk of being excluded from mainstream education, unless particular efforts are made to support them in such settings. These children…

The Role of Education in Freedom from Poverty as a Human Right

ERIC Educational Resources Information Center

Dhillon, Pradeep

2011-01-01

Education lies at the heart of the Universal Declaration of Human Rights (UDHR): "Education shall be directed to the full development of the human personality and to the strengthening of respect for human rights and fundamental freedoms". However, when education is mentioned in the philosophical literature on human rights, or even within…

English in Globalisation, a Lingua Franca or a Lingua Frankensteinia?

ERIC Educational Resources Information Center

Phillipson, Robert

2009-01-01

TESOL declares that it is a global organization. TESOL's expansionist ambitions dovetail with U.S. corporate and government global aims. This trend leads the author to conclude that even if U.S. TESOL were to more actively embrace the other languages of its emerging bilinguals, the languages of a more multilingual TESOL would still be…

The French Armed Forces Virology Unit: A Chronological Record of Ongoing Research on Orthopoxvirus

PubMed Central

Delaune, Déborah; Iseni, Frédéric; Ferrier-Rembert, Audrey; Peyrefitte, Christophe N.; Ferraris, Olivier

2017-01-01

Since the official declaration of smallpox eradication in 1980, the general population vaccination has ceased worldwide. Therefore, people under 40 year old are generally not vaccinated against smallpox and have no cross protection against orthopoxvirus infections. This naïve population may be exposed to natural or intentional orthopoxvirus emergences. The virology unit of the Institut de Recherche Biomédicale des Armées (France) has developed research programs on orthopoxviruses since 2000. Its missions were conceived to improve the diagnosis capabilities, to foster vaccine development, and to develop antivirals targeting specific viral proteins. The role of the virology unit was asserted in 2012 when the responsibility of the National Reference Center for the Orthopoxviruses was given to the unit. This article presents the evolution of the unit activity since 2000, and the past and current research focusing on orthopoxviruses. PMID:29295488

Development of Dielectric Elastomer Nanocomposites as Stretchable and Flexible Actuating Materials

NASA Astrophysics Data System (ADS)

Wang, Yu

Dielectric elastomers (DEs) are a new type of smart materials showing promising functionalities as energy harvesting materials as well as actuating materials for potential applications such as artificial muscles, implanted medical devices, robotics, loud speakers, micro-electro-mechanical systems (MEMS), tunable optics, transducers, sensors, and even generators due to their high electromechanical efficiency, stability, lightweight, low cost, and easy processing. Despite the advantages of DEs, technical challenges must be resolved for wider applications. A high electric field of at least 10-30 V/um is required for the actuation of DEs, which limits the practical applications especially in biomedical fields. We tackle this problem by introducing the multiwalled carbon nanotubes (MWNTs) in DEs to enhance their relative permittivity and to generate their high electromechanical responses with lower applied field level. This work presents the dielectric, mechanical and electromechanical properties of DEs filled with MWNTs. The micromechanics-based finite element models are employed to describe the dielectric, and mechanical behavior of the MWNT-filled DE nanocomposites. A sufficient number of models are computed to reach the acceptable prediction of the dielectric and mechanical responses. In addition, experimental results are analyzed along with simulation results. Finally, laser Doppler vibrometer is utilized to directly detect the enhancement of the actuation strains of DE nanocomposites filled with MWNTs. All the results demonstrate the effective improvement in the electromechanical properties of DE nanocomposites filled with MWNTs under the applied electric fields.

Étude de la structure des alliages vitreux Ag-As2S3 par diffraction de rayons X

NASA Astrophysics Data System (ADS)

Popescu, M.; Sava, F.; Cornet, A.; Broll, N.

2002-07-01

The structure of several silver alloyed arsenic chalocgenide has been determined by X-ray diffraction. For low silver doping the disordered layer structure, characteristic to the glassy AS2S3 is retained as demonstrated by the well developed first sharp diffraction peak in the X-ray diffraction pattern. For high amount of silver introduced in the As2S3 matrix, the disoredered layer configurations disappear, as shown by the diminishing and even disappearance of the first sharp diffraction peak in the X-ray patterns. A three-dimensional structure based on Ag2S -type configuration is formed. La structure de quelques alliages sulfure d'arsenic - argent a été determinée par diffraction de rayons X. Pour de faibles dopages à l'argent on conserve la structure desordonnées caractéristique des couches atomique d'As2S3 vitreux ; ceci est prouvé par la forte intensité du premier pic étroit de diffraction. Pour des plus grandes proportions d'argent la structure de l'alliage vitreux fait apparaître des unités structurales caractéristiques du cristal d'Ag2S et la configuration atomique avec des couches desordonnées disparaît (le premier pic étroit de diffraction s'évanouit) en faisant place à une structure tridimensionelle.

Congress Prepares for Student-Loan Crisis, while Declaring It Unlikely

ERIC Educational Resources Information Center

Field, Kelly

2008-01-01

Several months into a credit crunch that has led at least 20 lenders to leave the guaranteed loan program or suspend their lending operations, lawmakers have begun to respond with a sense of urgency, even as they seek to reassure students and parents that a crisis is unlikely and that federal student loans will still be available this fall. In the…

Dream actors in the theatre of memory: their role in the psychoanalytic process.

PubMed

Mancia, Mauro

2003-08-01

The author notes that neuropsychological research has discovered the existence of two long-term memory systems, namely declarative or explicit memory, which is conscious and autobiographical, and non-declarative or implicit memory, which is neither conscious nor verbalisable. It is suggested that pre-verbal and pre-symbolic experience in the child's primary relations is stored in implicit memory, where it constitutes an unconscious nucleus of the self which is not repressed and which influences the person's affective, emotional, cognitive and sexual life even as an adult. In the analytic relationship this unconscious part can emerge essentially through certain modes of communication (tone of voice, rhythm and prosody of the voice, and structure and tempo of speech), which could be called the 'musical dimension' of the transference, and through dream representations. Besides work on the transference, the critical component of the therapeutic action of psychoanalysis is stated to consist in work on dreams as pictographic and symbolic representations of implicit pre-symbolic and pre-verbal experiences. A case history is presented in which dream interpretation allowed some of a patient's early unconscious, non-repressed experiences to be emotionally reconstructed and made thinkable even though they were not actually remembered.

Memory Before and After Sleep in Patients with Moderate Obstructive Sleep Apnea

PubMed Central

Kloepfer, Corinna; Riemann, Dieter; Nofzinger, Eric A.; Feige, Bernd; Unterrainer, Josef; O'Hara, Ruth; Sorichter, Stephan; Nissen, Christoph

2009-01-01

Objective: The aim of this study was to investigate the effects of obstructive sleep apnea (OSA) on procedural and declarative memory encoding in the evening prior to sleep, on memory consolidation during subsequent sleep, and on retrieval in the morning after sleep. Methods: Memory performance (procedural mirror-tracing task, declarative visual and verbal memory task) and general neuropsychological performance were assessed before and after one night of polysomnographic monitoring in 15 patients with moderate OSA and 20 age-, sex-, and IQ-matched healthy subjects. Results: Encoding levels prior to sleep were similar across groups for all tasks. Conventional analyses of averaged mirror tracing performance suggested a significantly reduced overnight improvement in OSA patients. Single trial analyses, however, revealed that this effect was due to significantly flattened learning curves in the evening and morning session in OSA patients. OSA patients showed a significantly lower verbal retention rate and a non-significantly reduced visual retention rate after sleep compared to healthy subjects. Polysomnography revealed a significantly reduced REM density, increased frequency of micro-arousals, elevated apnea-hypopnea index, and subjectively disturbed sleep quality in OSA patients compared to healthy subjects. Conclusions: The results suggest that moderate OSA is associated with a significant impairment of procedural and verbal declarative memory. Future work is needed to further determine the contribution of structural or functional alterations in brain circuits relevant for memory, and to test whether OSA treatment improves or normalizes the observed deficits in learning. Citation: Kloepfer C; Riemann D; Nofzinger EA; Feige B; Unterrainer J; O'Hara R; Sorichter S; Nissen C. Memory before and after sleep in patients with moderate obstructive sleep apnea. J Clin Sleep Med 2009;5(6):540-548. PMID:20465021

Cost-effectiveness of drug-eluting coronary stents in Quebec, Canada.

PubMed

Brophy, James M; Erickson, Lonny J

2005-01-01

The aim of this investigation was to assess the incremental cost-effectiveness of replacing bare metal coronary stents (BMS) with drug-eluting stents (DES) in the Province of Quebec, Canada. The strategy used was a cost-effectiveness analysis from the perspective of the health-care provider, in the province of Quebec, Canada (population 7.5 million). The main outcome measure was the cost per avoided revascularization intervention. Based on the annual Quebec rate of 14,000 angioplasties with an average of 1.7 stents per procedure and a purchase cost of $2,600 Canadian dollar (CDN) for DES, 100 percent substitution of BMS with DES would require an additional $45.1 million CDN of funding. After the benefits of reduced repeat revascularization interventions are included, the incremental cost would be $35.2 million CDN. The cost per avoided revascularization intervention (18 percent coronary artery bypass graft, 82 percent percutaneous coronary intervention [PCI]) would be $23,067 CDN. If DES were offered selectively to higher risk populations, for example, a 20 percent subgroup with a relative restenosis risk of 2.5 times the current bare metal rate, the incremental cost of the program would be $4.9 million CDN at a cost of $7,800 per avoided revascularization procedure. Break-even costs for the program would occur at DES purchase cost of $1,161 for 100 percent DES use and $1,627 for selective 20 percent DES use for high-risk patients for restenosis (RR = 2.5). Univariate and Monte Carlo sensitivity analyses indicate that the parameters most affecting the analysis are the capacity to select patients at high risk of restenosis, the average number of stents used per PCI, baseline restenosis rates for BMS, the effectiveness ratio of restenosis prevention for DES versus BMS, the cost of DES, and the revascularization rate after initial PCI. Sensitivity analyses suggest little additional health benefits but escalating cost-effectiveness ratios once a DES penetration of 40 percent has been attained. Under current conditions in Quebec, Canada, selective use of DES in high-risk patients is the most acceptable strategy in terms of cost-effectiveness. Results of such an analysis would be expected to be similar in other countries with key model parameters similar to those used in this model. This model provides an example of how to evaluate the cost-effectiveness of selective use of a new technology in high-risk patients.

LHC, le Big Bang en éprouvette

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

Notre compréhension de l’Univers est en train de changer… Bar des Sciences - Tout public Débat modéré par Marie-Odile Montchicourt, journaliste de France Info. Evenement en vidéoconférence entre le Globe de la science et de l’innovation, le bar le Baloard de Montpellier et la Maison des Métallos à Paris. Intervenants au CERN : Philippe Charpentier et Daniel Froideveaux, physiciens au CERN. Intervenants à Paris : Vincent Bontemps, philosophe et chercheur au CEA ; Jacques Arnould, philosophe, historien des sciences et théologien, Jean-Jacques Beineix, réalisateur, producteur, scénariste de cinéma. Intervenants à Montpellier (LPTA) : André Neveu, physicien théoricien et directeur demore » recherche au CNRS ; Gilbert Moultaka, physicien théoricien et chargé de recherche au CNRS. Partenariat : CERN, CEA, IN2P3, Université MPL2 (LPTA) Dans le cadre de la Fête de la science 2008.« less

Early changes in cytokine expression in peste des petits ruminants disease.

PubMed

Baron, Jana; Bin-Tarif, Abdelghani; Herbert, Rebecca; Frost, Lorraine; Taylor, Geraldine; Baron, Michael D

2014-02-22

Peste des petits ruminants is a viral disease of sheep and goats that has spread through most of Africa as well as the Middle East and the Indian subcontinent. Although, the spread of the disease and its economic impact has made it a focus of international concern, relatively little is known about the nature of the disease itself. We have studied the early stages of pathogenesis in goats infected with six different isolates of Peste des petits ruminants virus representing all four known lineages of the virus. No lineage-specific difference in the pathogenicity of the virus isolates was observed, although there was evidence that even small numbers of cell culture passages could affect the degree of pathogenicity of an isolate. A consistent reduction in CD4+ T cells was observed at 4 days post infection (dpi). Measurement of the expression of various cytokines showed elements of a classic inflammatory response but also a relatively early induction of interleukin 10, which may be contributing to the observed disease.

The Global Governance of Bioethics: Negotiating UNESCO’s Universal Declaration on Bioethics and Human Rights (2005)

PubMed Central

Langlois, Adèle

2012-01-01

UNESCO’s Universal Declaration on Bioethics and Human Rights (2005) was drawn up by an independent panel of experts (the International Bioethics Committee) and negotiated by member states. UNESCO aimed for a participatory and transparent drafting process, holding national and regional consultations and seeking the views of various interest groups, including religious and spiritual ones. Furthermore, reflecting UNESCO’s broad interpretation of bioethics, the IBC included medics, scientists, lawyers and philosophers among its membership. Nevertheless, several potential stakeholders—academic scientists and ethicists, government policy-makers and NGO representatives—felt they had not been sufficiently consulted or even represented during the Declaration’s development. Better communications and understanding within and between national, regional and international layers of governance would help to avoid a recurrence of this problem in future negotiations. PMID:22724045

Stepping back to advance: Why IGD needs an intensified debate instead of a consensus.

PubMed

Quandt, Thorsten

2017-06-01

Based on their analysis of Internet gaming disorder (IGD) criteria, Kuss, Griffiths, and Pontes (2017) come to the conclusion that the current situation can be described as "chaos and confusion." Their assessment is not an exaggeration. It can be argued that there are even more issues, on logical/definitional and political/social levels: (a) the IGD diagnosis is lacking a well-defined object, (b) the cause and effect cannot be differentiated outside lab conditions, (c) the social and political effects of declaring a social behavior as a disease are worrying, and (d) a rushed diagnosis may construct an addiction with potentially harmful effects on (formerly) healthy populations. Instead of closing the debate by declaring a consensus and codifying IGD in the DSM, an undogmatic, intensified, and broader discussion is needed.

Screening for depression in adolescent paediatric patients: validity of the new Depression Screener for Teenagers (DesTeen).

PubMed

Pietsch, Kathrin; Allgaier, Antje-Kathrin; Frühe, Barbara; Rohde, Sabine; Hosie, Stuart; Heinrich, Martina; Schulte-Körne, Gerd

2011-09-01

Depression in adolescents is often hard to detect. In many cases paediatricians are the first point of contact. In order to increase recognition rates, screening instruments may be a helpful support for health care professionals. However, there is a lack of valid and economical screening instruments for primary care patients. Thus, the aim of the study was the development of the new Depression Screener for Teenagers (DesTeen) and its validation in a paediatric sample. 326 patients between 13 and 16 years old completed the DesTeen and a diagnostic interview, serving as gold standard. Prevalence rate for any depressive disorder (minor depression, major depression and dysthymia) was 12.6%. Psychometric properties were calculated. For validity measures, the area under the receiver operating characteristic curves (AUC) for any depressive disorder and the diagnostic subgroups was computed. DesTeen showed a high reliability (Cronbach's α=.87) and a high validity (AUC=.91). For the diagnostic subgroups AUC values did not significantly differ from overall accuracy of any depressive disorder (major depression: AUC=.95, p=.179; dysthymia: AUC=.88, p=.605; minor depression: AUC=.87, p=.327). The optimal cut-off point for any depressive disorder according to the Youden-Index yielded a sensitivity of .90 and a specificity of .80. An abbreviated 5-item version of DesTeen showed no loss in validity (AUC=.90, p=.695). Overall, DesTeen can be regarded as a valid screening instrument for adolescent paediatric patients. For practical use, the 5-item version is even more promising. A replication of these results is essential. Copyright © 2011 Elsevier B.V. All rights reserved.

Clear cell adenocarcinoma of cervix in 1-year-old girl without in utero exposure to diethylstilbestrol: an uncommon tumour at an uncommon age and site.

PubMed

Arora, Aditi; Rastogi, Anurag; Neyaz, Azfar; Husain, Nuzhat

2017-03-16

Adenocarcinoma of cervix constitutes about 10-15% cases of carcinoma cervix. Clear cell variant is even a rarer variant of adenocarcinoma. It rarely occurs in the paediatric age group and a known risk factor is in utero exposure to diethylstilbestrol (DES). We report here a case of primary cervical tumour in a 1-year-old girl, which was initially suspected to be an embryonal rhabdomyosarcoma botryoides. Histopathology with immunohistochemical analysis revealed clear cell adenocarcinoma. There was no maternal history of DES intake during pregnancy. We discuss the histopathological characteristics and clinical course of this unusual tumour. 2017 BMJ Publishing Group Ltd.

Fingerprinting Desmosine-Containing Elastin Peptides

NASA Astrophysics Data System (ADS)

Schräder, Christoph U.; Heinz, Andrea; Majovsky, Petra; Schmelzer, Christian E. H.

2015-05-01

Elastin is a vital protein of the extracellular matrix of jawed vertebrates and provides elasticity to numerous tissues. It is secreted in the form of its soluble precursor tropoelastin, which is subsequently cross-linked in the course of the elastic fiber assembly. The process involves the formation of the two tetrafunctional amino acids desmosine (DES) and isodesmosine (IDES), which are unique to elastin. The resulting high degree of cross-linking confers remarkable properties, including mechanical integrity, insolubility, and long-term stability to the protein. These characteristics hinder the structural elucidation of mature elastin. However, MS2 data of linear and cross-linked peptides released by proteolysis can provide indirect insights into the structure of elastin. In this study, we performed energy-resolved collision-induced dissociation experiments of DES, IDES, their derivatives, and DES-/IDES-containing peptides to determine characteristic product ions. It was found that all investigated compounds yielded the same product ion clusters at elevated collision energies. Elemental composition determination using the exact masses of these ions revealed molecular formulas of the type CxHyN, suggesting that the pyridinium core of DES/IDES remains intact even at relatively high collision energies. The finding of these specific product ions enabled the development of a similarity-based scoring algorithm that was successfully applied on LC-MS/MS data of bovine elastin digests for the identification of DES-/IDES-cross-linked peptides. This approach facilitates the straightforward investigation of native cross-links in elastin.

Fingerprinting desmosine-containing elastin peptides.

PubMed

Schräder, Christoph U; Heinz, Andrea; Majovsky, Petra; Schmelzer, Christian E H

2015-05-01

Elastin is a vital protein of the extracellular matrix of jawed vertebrates and provides elasticity to numerous tissues. It is secreted in the form of its soluble precursor tropoelastin, which is subsequently cross-linked in the course of the elastic fiber assembly. The process involves the formation of the two tetrafunctional amino acids desmosine (DES) and isodesmosine (IDES), which are unique to elastin. The resulting high degree of cross-linking confers remarkable properties, including mechanical integrity, insolubility, and long-term stability to the protein. These characteristics hinder the structural elucidation of mature elastin. However, MS(2) data of linear and cross-linked peptides released by proteolysis can provide indirect insights into the structure of elastin. In this study, we performed energy-resolved collision-induced dissociation experiments of DES, IDES, their derivatives, and DES-/IDES-containing peptides to determine characteristic product ions. It was found that all investigated compounds yielded the same product ion clusters at elevated collision energies. Elemental composition determination using the exact masses of these ions revealed molecular formulas of the type CxHyN, suggesting that the pyridinium core of DES/IDES remains intact even at relatively high collision energies. The finding of these specific product ions enabled the development of a similarity-based scoring algorithm that was successfully applied on LC-MS/MS data of bovine elastin digests for the identification of DES-/IDES-cross-linked peptides. This approach facilitates the straightforward investigation of native cross-links in elastin.

La microscopie ionique analytique des tissus biologiques

NASA Astrophysics Data System (ADS)

Galle, P.

Proposed in 1960 by R. Castaing and G. Slodzian, secondary ion emission microanalysis is a microanalytical method which is now largely used for the study of inert material. The instrument called the analytical ion microscope can also be used for the study of biological spécimens ; images representing the distribution of a given stable or radioactive isotope in a tissue section are obtained with a resolution of 0.5 μm. Among the characteristics of this method, two are of particular interest in biological research : its capacity for isotopic analysis and its very high sensitivity which makes possible for the first time a chemical analysis of element at a very low or even at a trace concentration in a microvolume. Proposé en 1960 par R. Castaing et G. Slodzian, la microanalyse par émission ionique secondaire est une méthode qui permet, entre autre, d'obtenir des images représentant la distribution des isotopes présents à la surface d'un échantillon solide avec une résolution de 0,5 μm. D'intérêt très général, cette méthode a été d'abord largement utilisée pour l'étude des matériaux inertes. Elle offre en outre des possibilités entièrement nouvelles dans le domaine de la recherche biomédicale. L'instrument réalisé, le microscope ionique analytique présente deux caractéristiques particulièrement intéressantes pour la biologie : la possibilité d'analyse isotopique, et l'extrême sensibilité permettant de détecter et de localiser dans une coupe histologique des éléments à des concentrations très faibles voire à l'état de trace.

Dispositifs semi-conducteurs pour biodetection photonique et imagerie hyperspectrale

NASA Astrophysics Data System (ADS)

Lepage, Dominic

La creation d'un microsysteme d'analyse biochimique, capable de livrer des diagnostics preliminaires sur la quantification d'elements pathogenes, est un defi multidisciplinaire ayant un impact potentiel important sur la majorite des activites humaines en sante et securite. En effet, un dispositif integre, peu dispendieux et livrant des resultats facilement interpretables, permettrait une vulgarisation des capacites de biodetection a travers differents domaines d'applications societaires et industriels. Le present document se concentre sur l'integration monolithique d'une methode de biocaracterisation dans le but de generer un transducteur miniaturise et efficace, element central d'un microsysteme de detection. Le projet de recherche ici presente vise l'etude de l'applicabilite d'un capteur plasmonique integre par l'entremise de nanostructures semi-conductrices aux proprietes quantiques et luminescentes. L'approche presentee est globale; c'est-a-dire qu'on vise a repondre aux questions fondamentales impliquant la comprehension des phenomenes photoniques, le developpement et la fabrication des dispositifs, les methodes de caracterisations possibles ainsi que l'application d'un transducteur SPR integre a la biodetection. En d'autres termes : dans quelles circonstances et comment un transducteur plasmonique integre doit-il etre realise pour l'application a la detection delocalisee d'elements pathogenes? Dans le but d'engendrer un instrument simple a l'echelle de l'usager, l'integration de la connaissance a l'echelle du design est donc effectuee. Ainsi, des capteurs plasmoniques monolithiques sont concus a l'aide de modeles theoriques ici presentes. Un instrument de mesure hyperspectrale conjuguee permettant de cartographier directement la relation de dispersion des plasmons diffractes a ete construit et teste. Cet instrument est employe a la cartographie d'elements de diffusion. Finalement, une demonstration du fonctionnement du dispositif, appliquee a la biocaracterisation d'evenements simples, tels que l'albumine de serum bovin et la detection d'une souche specifique d'influenza A, est livree. Ceci repond donc a la question de faisabilite d'un nanosysteme plasmonique applicable a la detection de pathogenes. Mots-Clefs: Biocapteur; Plasmons de surface; Diffusion lumineuse; Semi-conducteur quantique; Microscopie conjuguee; Virus Influenza A

Somalia: A Country Study.

DTIC Science & Technology

1981-10-01

in the inheri- tance of valued property (camels or land). Few girls were sent to school and even fewer continued beyond the elementary level...of 1978, was the Multipurpose Cooperative Society, encompassing two to four villages. Property (land, equipment, and livestock) remained in...October 1975 the country’s first major land tenure law declared that all land was state property , in effect nationalizing all holdings. This concept

The Military Chaplaincy: A Study in Role Conflict

DTIC Science & Technology

1984-04-10

America Progressive National Eiaptist Reformed Church in America Reorganized Church of Jesus Christ of the Latter Day Saints Seventh Day Adventist ...early days in the life of this country, the role of the chaplain has significantly changed and been con- stantly under the close scrutiny of both...be con- sidered a violation of church-state separation. That declaration is being challenged even to this day . Opposing voices

Dielectric elastomer memory

NASA Astrophysics Data System (ADS)

O'Brien, Benjamin M.; McKay, Thomas G.; Xie, Sheng Q.; Calius, Emilio P.; Anderson, Iain A.

2011-04-01

Life shows us that the distribution of intelligence throughout flexible muscular networks is a highly successful solution to a wide range of challenges, for example: human hearts, octopi, or even starfish. Recreating this success in engineered systems requires soft actuator technologies with embedded sensing and intelligence. Dielectric Elastomer Actuator(s) (DEA) are promising due to their large stresses and strains, as well as quiet flexible multimodal operation. Recently dielectric elastomer devices were presented with built in sensor, driver, and logic capability enabled by a new concept called the Dielectric Elastomer Switch(es) (DES). DES use electrode piezoresistivity to control the charge on DEA and enable the distribution of intelligence throughout a DEA device. In this paper we advance the capabilities of DES further to form volatile memory elements. A set reset flip-flop with inverted reset line was developed based on DES and DEA. With a 3200V supply the flip-flop behaved appropriately and demonstrated the creation of dielectric elastomer memory capable of changing state in response to 1 second long set and reset pulses. This memory opens up applications such as oscillator, de-bounce, timing, and sequential logic circuits; all of which could be distributed throughout biomimetic actuator arrays. Future work will include miniaturisation to improve response speed, implementation into more complex circuits, and investigation of longer lasting and more sensitive switching materials.

Short Sleep Makes Declarative Memories Vulnerable to Stress in Humans.

PubMed

Cedernaes, Jonathan; Rångtell, Frida H; Axelsson, Emil K; Yeganeh, Adine; Vogel, Heike; Broman, Jan-Erik; Dickson, Suzanne L; Schiöth, Helgi B; Benedict, Christian

2015-12-01

This study sought to investigate the role of nocturnal sleep duration for the retrieval of oversleep consolidated memories, both prior to and after being cognitively stressed for ∼30 minutes the next morning. Participants learned object locations (declarative memory task comprising 15 card pairs) and a finger tapping sequence (procedural memory task comprising 5 digits) in the evening. After learning, participants either had a sleep opportunity of 8 hours (between ∼23:00 and ∼07:00, full sleep condition) or they could sleep between ∼03:00 and ∼07:00 (short sleep condition). Retrieval of both memory tasks was tested in the morning after each sleep condition, both before (∼08:30) and after being stressed (∼09:50). Sleep laboratory. 15 healthy young men. The analyses demonstrated that oversleep memory changes did not differ between sleep conditions. However, in their short sleep condition, following stress hallmarked by increased subjective stress feelings, the men were unable to maintain their pre-stress performance on the declarative memory task, whereas their performance on the procedural memory task remained unchanged. While men felt comparably subjectively stressed by the stress intervention, overall no differences between pre- and post-stress recalls were observed following a full night of sleep. The findings suggest that 8-h sleep duration, within the range recommended by the US National Sleep Foundation, may not only help consolidate newly learned procedural and declarative memories, but also ensure full access to both during periods of subjective stress. © 2015 Associated Professional Sleep Societies, LLC.

Sleep facilitates consolidation of emotional declarative memory.

PubMed

Hu, Peter; Stylos-Allan, Melinda; Walker, Matthew P

2006-10-01

Both sleep and emotion are known to modulate processes of memory consolidation, yet their interaction is poorly understood. We examined the influence of sleep on consolidation of emotionally arousing and neutral declarative memory. Subjects completed an initial study session involving arousing and neutral pictures, either in the evening or in the morning. Twelve hours later, after sleeping or staying awake, subjects performed a recognition test requiring them to discriminate between these original pictures and novel pictures by responding "remember,"know" (familiar), or "new." Selective sleep effects were observed for consolidation of emotional memory: Recognition accuracy for know judgments of arousing stimuli improved by 42% after sleep relative to wake, and recognition bias for remember judgments of these stimuli increased by 58% after sleep relative to wake (resulting in more conservative responding). These findings hold important implications for understanding of human memory processing, suggesting that the facilitation of memory for emotionally salient information may preferentially develop during sleep.

Flipped Instruction in English Language Teacher Education: A Design-­Based Study in a Complex, Open-­Ended Learning Environment

ERIC Educational Resources Information Center

Egbert, Joy; Herman, David; Lee, HyunGyung

2015-01-01

Reports of flipped classrooms across areas in the field of ESL are rare, and those that address the complexities of ESL teacher education, particularly the methods course in which procedural knowledge is privileged over declarative knowledge, are even rarer. This paper uses a design-­-based research (DBR) approach to explore the flip of an ESL…

An ultra short episode of sleep is sufficient to promote declarative memory performance.

PubMed

Lahl, Olaf; Wispel, Christiane; Willigens, Bernadette; Pietrowsky, Reinhard

2008-03-01

Various studies have demonstrated that a night of sleep has a beneficial effect on the retention of previously acquired declarative material. In two experiments, we addressed the question of whether this effect extends to daytime naps. In the first experiment we assessed free recall of a list of 30 words after a 60 min retention interval that was either filled with daytime napping or waking activity. Memory performance was significantly enhanced after napping as opposed to waking but was not correlated with time spent in slow wave sleep or total sleep time within the napping condition. The second experiment was designed to clarify the role of total sleep time and therefore included an additional third group, which was allowed to nap for no longer than 6 min on average. In comparing word recall after conditions of no napping (waking), short napping, and long napping, we found superior recall for both nap conditions in contrast to waking as well as for long naps in contrast to short naps. These results demonstrate that even an ultra short period of sleep is sufficient to enhance memory processing. We suggest that the mere onset of sleep may initiate active processes of consolidation which - once triggered - remain effective even if sleep is terminated shortly thereafter.

[Reporting ethics board approval in German medical theses and journals].

PubMed

Zenz, Michael; Zenz, Julia; Grieger, Maximilian

2018-06-05

Since 1975, the Declaration of Helsinki of the World Medical Association (WMA) has clearly required ethics committee approval for research into humans. Nevertheless, this Declaration is violated quite often. As many English-language publications have addressed the theme of ethics board approval in theses and other published works, it is now to be investigated in Germany for the first time.From 2013 to 2014, a total of 1,482 medical theses at four selected universities in addition to three German-language scientific journals were reviewed. In 543 theses, reference to ethics approval would have been required according to the criteria of the Declaration of Helsinki.However, ethics approval was stated in only 58.7% of cases, and even less frequently if the prevailing doctoral regulations or instructions did not refer to the necessity of obtaining ethics approval. Theses on pediatrics mentioned ethics approval most frequently (78.6%), whereas the proportion of surgical papers was the lowest (34.9%). Among the journals, Der Nervenarzt mentioned ethics approval most frequently (59.4%) and Der Chirurg least frequently (30%).Our results point to significant deficits in mentioning ethics approval in medical theses and publications. These deficits could easily be compensated for by a thorough approach of the referees of doctoral regulations and by journal reviewers and editors.

Input Subject Diversity Accelerates the Growth of Tense and Agreement: Indirect Benefits From a Parent-Implemented Intervention

PubMed Central

Rispoli, Matthew; Holt, Janet K.

2017-01-01

Purpose This follow-up study examined whether a parent intervention that increased the diversity of lexical noun phrase subjects in parent input and accelerated children's sentence diversity (Hadley et al., 2017) had indirect benefits on tense/agreement (T/A) morphemes in parent input and children's spontaneous speech. Method Differences in input variables related to T/A marking were compared for parents who received toy talk instruction and a quasi-control group: input informativeness and full is declaratives. Language growth on tense agreement productivity (TAP) was modeled for 38 children from language samples obtained at 21, 24, 27, and 30 months. Parent input properties following instruction and children's growth in lexical diversity and sentence diversity were examined as predictors of TAP growth. Results Instruction increased parent use of full is declaratives (ηp 2 ≥ .25) but not input informativeness. Children's sentence diversity was also a significant time-varying predictor of TAP growth. Two input variables, lexical noun phrase subject diversity and full is declaratives, were also significant predictors, even after controlling for children's sentence diversity. Conclusions These findings establish a link between children's sentence diversity and the development of T/A morphemes and provide evidence about characteristics of input that facilitate growth in this grammatical system. PMID:28892819

An Assessment of Fatigue Damage and Crack Growth Prediction Techniques (L’Evaluation de l’Endommagement en Fatigue et les Techniques de Prediction de la Propagation des Fissures)

DTIC Science & Technology

1994-03-01

reality the structure of even one individual aircraft consists of many bat- ches and the tens of thousand of cars of one type manufactured in even...generated neural network power spectral densities of surface pressures are used to augment existing data and then load an elastic finite clement...investigated for possible use in augmenting this information which is required for fatigue life calculations. Since empennage environments on fighter

LHC, le Big Bang en éprouvette

ScienceCinema

None

2017-12-09

Notre compréhension de l’Univers est en train de changer… Bar des Sciences - Tout public Débat modéré par Marie-Odile Montchicourt, journaliste de France Info. Evenement en vidéoconférence entre le Globe de la science et de l’innovation, le bar le Baloard de Montpellier et la Maison des Métallos à Paris. Intervenants au CERN : Philippe Charpentier et Daniel Froideveaux, physiciens au CERN. Intervenants à Paris : Vincent Bontemps, philosophe et chercheur au CEA ; Jacques Arnould, philosophe, historien des sciences et théologien, Jean-Jacques Beineix, réalisateur, producteur, scénariste de cinéma. Intervenants à Montpellier (LPTA) : André Neveu, physicien théoricien et directeur de recherche au CNRS ; Gilbert Moultaka, physicien théoricien et chargé de recherche au CNRS. Partenariat : CERN, CEA, IN2P3, Université MPL2 (LPTA) Dans le cadre de la Fête de la science 2008

Mesure de la fraction d'evenements a quatre quarks dans les desintegrations multihadroniques du boson Z au LEP

NASA Astrophysics Data System (ADS)

Lefebvre, Eric

Cette thèse propose de tester la Chromodynamique Quantique (QCD) en effectuant une mesure précise d'une des trois constantes fondamentales du groupe de symétrie SU(3) utilisé pour décrire la physique des interactions fortes. Cette constante fondamentale, appelée TF, est reliée à certains états finaux spécifiques des désintégrations du Z0. Ces états apparaissent sous forme de perturbations du deuxième ordre en as et sont illustrés par des diagrammes de Feynman. À cet ordre, la chromodynamique prévoit deux types de diagrammes de Feynman distincts; le premier contient, un quark, un antiquark et deux gluons, et le second, deux quarks et deux antiquarks. La constante TF est directement proportionnelle à la fraction d'événements à deux quarks et deux antiquarks qui est l'objet de notre mesure. Notre mesure est fondée sur l'étude des événements à quatre partons dans l'état final. Ces quatre partons, en s'hadronisant, produisent quatre jets de particules qui peuvent être détectés expérimentalement et identifiés à l'aide d'algorithmes de reconstruction des jets. Des observables angulaires nous permettent de faire une discrimination parmi les états finaux de la désintégration du Z0, et ainsi déterminer la valeur de la fraction d'événements à deux quarks et deux antiquarks fq. Cette fraction peut s'exprimer par le rapport de la fraction observée expérimentalement fexq sur la fraction théorique fthq , R4q=fex qfthq. Afin d'améliorer la mesure de cette fraction et de diminuer le bruit causé par une contamination des événements d'ordres supérieurs, nous avons développe une méthode d'extrapolation. Cette méthode s'appuie sur la caractérisation de l'espace de phase des événements, exprimée par les paramètres yij. Les mesures de R4q que nous obtenons sont: R4q=2,27+0,29 -0,56 à l'aide d'une méthode conventionnelle avec la condition de sélection y34 > 0,020 > y45, et R4q=1,22+0,56 -0,71 à l'aide de notre méthode d'extrapolation avec la condition de sélection y34 > 0,020. Nous en concluons que notre méthode d'extrapolation est efficace pour la réduction du bruit de fond causé par les événements d'ordre supérieur, et qu'un bon accord est obtenu entre la mesure expérimentale et la prédiction théorique. La mesure dite conventionnelle permet d'apprécier la réduction de la contamination, sans laquelle, un écart de plus de deux sigma apparaît entre la mesure et la prédiction. L'ensemble de l'analyse, des graphiques, des tableaux, et des reésultats des chapitres 3, 4, et 5 ainsi que des deux appendices, représente la contribution personnelle, à cette étude, de l'auteur de cette thèse.

Angina and Ischemia at 2 Years With Bioresorbable Vascular Scaffolds and Metallic Drug-eluting Stents. ESTROFA Ischemia BVS-mDES Study.

PubMed

de la Torre Hernández, José M; Rumoroso, José R; Ojeda, Soledad; Brugaletta, Salvatore; Cascón, José D; Ruisánchez, Cristina; Sánchez Gila, Joaquín; Roa, Jessica; Tizón, Helena; Gutiérrez, Hipólito; Larman, Mariano; García Camarero, Tamara; Pinar, Eduardo; Díaz, José F; Pan, Manuel; Morillas Bueno, Miren; Oyonarte, José M; Ruiz Guerrero, Luis; Ble, Mireia; Rubio Patón, Ramón; Arnold, Román; Echegaray, Kattalin; de la Morena, Gonzalo; Sabate, Manel

2018-05-01

Bioresorbable vascular scaffolds (BVS) have the potential to restore vasomotion but the clinical implications are unknown. We sought to evaluate angina and ischemia in the long-term in patients treated with BVS and metallic drug-eluting stents (mDES). Multicenter study including patients with 24 ± 6 months of uneventful follow-up, in which stress echocardiography was performed and functional status was assessed by the Seattle Angina Questionnaire (SAQ). The primary endpoint was a positive result in stress echocardiography. The study included 102 patients treated with BVS and 106 with mDES. There were no differences in the patients' baseline characteristics. Recurrent angina was found in 18 patients (17.6%) in the BVS group vs 25 (23.5%) in the mDES group (P = .37), but SAQ results were significantly better in the BVS group (angina frequency 96.0 ± 8.0 vs 89.2 ± 29.7; P = .02). Stress echocardiography was positive in 11/92 (11.9%) of BVS patients vs 9/96 (9.4%) of mDES patients in the (P = .71) and angina was induced in 2/102 (1.9%) vs 7/106 (6.6%) (P = .18), respectively, but exercise performance was better in the BVS group even in those with positive tests (exercise duration 9.0 ± 2.0minutes vs 7.7 ± 1.8minutes; P = .02). A propensity score matching analysis yielded similar results. The primary endpoint was similar in both groups. In addition, recurrent angina was similar in patients with BVS and mDES. The better functional status, assessed by means of SAQ and exercise performance, detected in patients receiving BVS should be confirmed in further studies. Copyright © 2017 Sociedad Española de Cardiología. Published by Elsevier España, S.L.U. All rights reserved.

The Threat Detection System that Cried Wolf: Reconciling Developers with Operators

DTIC Science & Technology

2017-01-01

generating false alarms when true threats are not present. As a result, operators lose faith in the systems—ignoring them or even turning them off and...taking the chance that a true threat will not appear. This article reviews statistical concepts to reconcile the performance metrics that summarize a...the fraction of true threats for which the system correctly declares an alarm. Conversely, Pfa describes the fraction of true clutter ( true non

Wireless Emergency Alerts: New York City Demonstration

DTIC Science & Technology

2013-06-01

CMU/SEI-2012-SR-016 | 16  Consider factors affecting continuity of operations, such as support of remote employ- ees, mobile alerting...visitors and tourists , we’ll be even safer when authorities can broadcast warnings to everyone in a geographic area regardless of where they came from or...using technology to help keep people safe. [Office of the Mayor 2011b] Mayor Bloomberg declared his intention to make this new service available to New

Discrete memory impairments in largely pure chronic users of MDMA.

PubMed

Wunderli, Michael D; Vonmoos, Matthias; Fürst, Marina; Schädelin, Katrin; Kraemer, Thomas; Baumgartner, Markus R; Seifritz, Erich; Quednow, Boris B

2017-10-01

Chronic use of 3,4-methylenedioxymethamphetamine (MDMA, "ecstasy") has repeatedly been associated with deficits in working memory, declarative memory, and executive functions. However, previous findings regarding working memory and executive function are inconclusive yet, as in most studies concomitant stimulant use, which is known to affect these functions, was not adequately controlled for. Therefore, we compared the cognitive performance of 26 stimulant-free and largely pure (primary) MDMA users, 25 stimulant-using polydrug MDMA users, and 56 MDMA/stimulant-naïve controls by applying a comprehensive neuropsychological test battery. Neuropsychological tests were grouped into four cognitive domains. Recent drug use was objectively quantified by 6-month hair analyses on 17 substances and metabolites. Considerably lower mean hair concentrations of stimulants (amphetamine, methamphetamine, methylphenidate, cocaine), opioids (morphine, methadone, codeine), and hallucinogens (ketamine, 2C-B) were detected in primary compared to polydrug users, while both user groups did not differ in their MDMA hair concentration. Cohen's d effect sizes for both comparisons, i.e., primary MDMA users vs. controls and polydrug MDMA users vs. controls, were highest for declarative memory (d primary =.90, d polydrug =1.21), followed by working memory (d primary =.52, d polydrug =.96), executive functions (d primary =.46, d polydrug =.86), and attention (d primary =.23, d polydrug =.70). Thus, primary MDMA users showed strong and relatively discrete declarative memory impairments, whereas MDMA polydrug users displayed broad and unspecific cognitive impairments. Consequently, even largely pure chronic MDMA use is associated with decreased performance in declarative memory, while additional deficits in working memory and executive functions displayed by polydrug MDMA users are likely driven by stimulant co-use. Copyright © 2017 Elsevier B.V. and ECNP. All rights reserved.

Modelisation de la diffusion sur les surfaces metalliques: De l'adatome aux processus de croissance

NASA Astrophysics Data System (ADS)

Boisvert, Ghyslain

Cette these est consacree a l'etude des processus de diffusion en surface dans le but ultime de comprendre, et de modeliser, la croissance d'une couche mince. L'importance de bien mai triser la croissance est primordiale compte tenu de son role dans la miniaturisation des circuits electroniques. Nous etudions ici les surface des metaux nobles et de ceux de la fin de la serie de transition. Dans un premier temps, nous nous interessons a la diffusion d'un simple adatome sur une surface metallique. Nous avons, entre autres, mis en evidence l'apparition d'une correlation entre evenements successifs lorsque la temperature est comparable a la barriere de diffusion, i.e., la diffusion ne peut pas etre associee a une marche aleatoire. Nous proposons un modele phenomenologique simple qui reproduit bien les resultats des simulations. Ces calculs nous ont aussi permis de montrer que la diffusion obeit a la loi de Meyer-Neldel. Cette loi stipule que, pour un processus active, le prefacteur augmente exponentiellement avec la barriere. En plus, ce travail permet de clarifier l'origine physique de cette loi. En comparant les resultats dynamiques aux resultats statiques, on se rend compte que la barriere extraite des calculs dynamiques est essentiellement la meme que celle obtenue par une approche statique, beaucoup plus simple. On peut donc obtenir cette barriere a l'aide de methodes plus precises, i.e., ab initio, comme la theorie de la fonctionnelle de la densite, qui sont aussi malheureusement beaucoup plus lourdes. C'est ce que nous avons fait pour plusieurs systemes metalliques. Nos resultats avec cette derniere approche se comparent tres bien aux resultats experimentaux. Nous nous sommes attardes plus longuement a la surface (111) du platine. Cette surface regorge de particularites interessantes, comme la forme d'equilibre non-hexagonale des i lots et deux sites d'adsorption differents pour l'adatome. De plus, des calculs ab initio precedents n'ont pas reussi a confirmer la forme d'equilibre et surestiment grandement la barriere. Nos calculs, plus complets et dans un formalisme mieux adapte a ce genre de probleme, predisent correctement la forme d'equilibre, qui est en fait due a un relachement different du stress de surface aux deux types de marches qui forment les cotes des i lots. Notre valeur pour la barriere est aussi fortement diminuee lorsqu'on relaxe les forces sur les atomes de la surface, amenant le resultat theorique beaucoup plus pres de la valeur experimentale. Nos calculs pour le cuivre demontre en effet que la diffusion de petits i lots pendant la croissance ne peut pas etre negligee dans ce cas, mettant en doute la valeur des interpretations des mesures experimentales. (Abstract shortened by UMI.)

48 CFR 218.203 - Incidents of national significance, emergency declaration, or major disaster declaration.

Code of Federal Regulations, 2013 CFR

2013-10-01

... significance, emergency declaration, or major disaster declaration. 218.203 Section 218.203 Federal Acquisition... significance, emergency declaration, or major disaster declaration. (1) Establishing or maintaining alternative... awarded by contracting officers in the conduct of emergency operations, such as responses to natural...

48 CFR 218.203 - Incidents of national significance, emergency declaration, or major disaster declaration.

Code of Federal Regulations, 2011 CFR

2011-10-01

... significance, emergency declaration, or major disaster declaration. 218.203 Section 218.203 Federal Acquisition... significance, emergency declaration, or major disaster declaration. (1) Establishing or maintaining alternative... awarded by contracting officers in the conduct of emergency operations, such as responses to natural...

48 CFR 218.203 - Incidents of national significance, emergency declaration, or major disaster declaration.

Code of Federal Regulations, 2014 CFR

2014-10-01

... significance, emergency declaration, or major disaster declaration. 218.203 Section 218.203 Federal Acquisition... significance, emergency declaration, or major disaster declaration. (1) Establishing or maintaining alternative... awarded by contracting officers in the conduct of emergency operations, such as responses to natural...

48 CFR 218.203 - Incidents of national significance, emergency declaration, or major disaster declaration.

Code of Federal Regulations, 2010 CFR

2010-10-01

... significance, emergency declaration, or major disaster declaration. 218.203 Section 218.203 Federal Acquisition... significance, emergency declaration, or major disaster declaration. (1) Establishing or maintaining alternative... awarded by contracting officers in the conduct of emergency operations, such as responses to natural...

Impact of stent length on clinical outcomes of first-generation and new-generation drug-eluting stents.

PubMed

Konishi, Hirokazu; Miyauchi, Katsumi; Dohi, Tomotaka; Tsuboi, Shuta; Ogita, Manabu; Naito, Ryo; Kasai, Takatoshi; Tamura, Hiroshi; Okazaki, Shinya; Isoda, Kikuo; Daida, Hiroyuki

2016-04-01

The aim of this study is to compare first- and new-generation drug-eluting stents (DESs) which are implanted in long lesion. Stent length is known to be a predictor of adverse events after percutaneous coronary intervention (PCI), even with the first-generation DESs. The introduction of new-generation DESs has reduced the rates of adverse clinical events. However, the impact of stent length on long-term clinical outcomes is not well known. A total of 1181 consecutive patients who underwent PCI using either a first-generation DES (n = 885) or a new-generation DES (n = 296) between 2004 and 2011 were investigated. In each of the stent groups, the patients were divided into two groups by stent length (>32 and ≤32 mm) and compared. During the follow-up period, the incidence of major adverse cardiac events (MACEs) was significantly higher for patients with long stents implanted than with short stents (P < 0.01; log-rank test) in the first-generation DES group. However, there was no difference in the incidence of MACEs between the long- and short-stent groups in the new-generation DES group (P = 0.24; log-rank test). On multivariate Cox regression analysis, stent length was not associated with adverse events in the new-generation DES groups [hazard ratio (HR) 0.87; 95 % confidence interval (95 % CI) 0.71-1.04; P = 0.14]. Implanted stent length was significantly associated with a higher risk of MACEs in patients who received first-generation DESs, but not in patients who received the new-generation DESs.

19 CFR 148.14 - Family declarations.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 19 Customs Duties 2 2011-04-01 2011-04-01 false Family declarations. 148.14 Section 148.14 Customs... (CONTINUED) PERSONAL DECLARATIONS AND EXEMPTIONS Declarations § 148.14 Family declarations. A family group... declare orally articles acquired abroad for the personal or household use of any member of the family if...

19 CFR 148.14 - Family declarations.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 19 Customs Duties 2 2014-04-01 2014-04-01 false Family declarations. 148.14 Section 148.14 Customs... (CONTINUED) PERSONAL DECLARATIONS AND EXEMPTIONS Declarations § 148.14 Family declarations. A family group... declare orally articles acquired abroad for the personal or household use of any member of the family if...

19 CFR 148.14 - Family declarations.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 19 Customs Duties 2 2010-04-01 2010-04-01 false Family declarations. 148.14 Section 148.14 Customs... (CONTINUED) PERSONAL DECLARATIONS AND EXEMPTIONS Declarations § 148.14 Family declarations. A family group... declare orally articles acquired abroad for the personal or household use of any member of the family if...

Making Wireless Networks Secure for NASA Mission Critical Applications using Virtual Private Network (VPN) Technology

NASA Technical Reports Server (NTRS)

Nichols, Kelvin F.; Best, Susan; Schneider, Larry

2004-01-01

With so many security issues involved with wireless networks, the technology has not been fully utilized in the area of mission critical applications. These applications would include the areas of telemetry, commanding, voice and video. Wireless networking would allow payload operators the mobility to take computers outside of the control room to their offices and anywhere else in the facility that the wireless network was extended. But the risk is too great of having someone sit just inside of your wireless network coverage and intercept enough of your network traffic to steal proprietary data from a payload experiment or worse yet hack back into your system and do even greater harm by issuing harmful commands. Wired Equivalent Privacy (WEP) is improving but has a ways to go before it can be trusted to protect mission critical data. Today s hackers are becoming more aggressive and innovative, and in order to take advantage of the benefits that wireless networking offer, appropriate security measures need to be in place that will thwart hackers. The Virtual Private Network (VPN) offers a solution to the security problems that have kept wireless networks from being used for mission critical applications. VPN provides a level of encryption that will ensure that data is protected while it is being transmitted over a wireless local area network (IAN). The VPN allows a user to authenticate to the site that the user needs to access. Once this authentication has taken place the network traffic between that site and the user is encapsulated in VPN packets with the Triple Data Encryption Standard (3DES). 3DES is an encryption standard that uses a single secret key to encrypt and decrypt data. The length of the encryption key is 168 bits as opposed to its predecessor DES that has a 56-bit encryption key. Even though 3DES is the common encryption standard for today, the Advance Encryption Standard (AES), which provides even better encryption at a lower cycle cost is growing acceptance. The user computer running the VPN client and the. target site that is running the . VPN firewall exchange this encryption key and therefore are the only ones that are able to decipher the data. The level of encryption offered by the VPN is making it possible for wireless networks to pass the strict security policies that have kept them from being used in the past. Now people will be able to benefit from the many advantages that wireless networking has to offer in the area of mission critical applications.

Making Wireless Networks Secure for NASA Mission Critical Applications Using Virtual Private Network (VPN) Technology

NASA Technical Reports Server (NTRS)

Nichols, Kelvin F.; Best, Susan; Schneider, Larry

2004-01-01

With so many security issues involved with wireless networks, the technology has not been fully utilized in the area of mission critical applications. These applications would include the areas of telemetry, commanding, voice and video. Wireless networking would allow payload operators the mobility to take computers outside of the control room to their off ices and anywhere else in the facility that the wireless network was extended. But the risk is too great of having someone sit just inside of your wireless network coverage and intercept enough of your network traffic to steal proprietary data from a payload experiment or worse yet hack back into your system and do even greater harm by issuing harmful commands. Wired Equivalent Privacy (WEP) is improving but has a ways to go before it can be trusted to protect mission critical data. Today s hackers are becoming more aggressive and innovative, and in order to take advantage of the benefits that wireless networking offer, appropriate security measures need to be in place that will thwart hackers. The Virtual Private Network (VPN) offers a solution to the security problems that have kept wireless networks from being used for mission critical applications. VPN provides a level of encryption that will ensure that data is protected while it is being transmitted over a wireless local area network (LAN). The VPN allows a user to authenticate to the site that the user needs to access. Once this authentication has taken place the network traffic between that site and the user is encapsulated in VPN packets with the Triple Data Encryption Standard (3DES). 3DES is an encryption standard that uses a single secret key to encrypt and decrypt data. The length of the encryption key is 168 bits as opposed to its predecessor DES that has a 56-bit encryption key. Even though 3DES is the common encryption standard for today, the Advance Encryption Standard (AES), which provides even better encryption at a lower cycle cost is growing acceptance. The user computer running the VPN client and the target site that is running the VPN firewall exchange this encryption key and therefore are the only ones that are able to decipher the data. The level of encryption offered by the VPN is making it possible for wireless networks to pass the strict security policies that have kept them from being used in the past. Now people will be able to benefit from the many advantages that wireless networking has to offer in the area of mission critical applications.

Safety, effectiveness and comparability of professional skin cleansers.

PubMed

Terhaer, Flora K; Bock, Meike; Fartasch, Manigé; Gabard, Bernard; Elsner, Peter; Kleesz, Peter; Landeck, Lilla; Pohrt, Ute; Seyfarth, Florian; Schliemann, Sibylle; Diepgen, Thomas L; Zagrodnik, Fred; John, Swen Malte

2010-10-01

There are no widely-accepted methodical specifications with which to objectify cleansing effectiveness and skin compatibility of occuptional skin cleansing products in Europe. Therefore the German Social Insurance Agency (DGUV) initiated a study with the goal to evaluate such products in view of the potency and the safety of hand cleansers. A market analysis was a part of the project. The product descriptions and safety data sheets of 120 products (5-20/manufacturer) of 11 manufacturers were evaluated between 02/2008 and 04/2008. The manufacturers used mainly ingredients of low irritancy. The declaration of the applied ingredients was in the majority of the cases correctly labeled according to the INCI Declaration. Although there was documentation of skin tolerability for most products, the manufacturers used widely differing tests of skin compatibility. Evidences for cleansing effectiveness were not declared or have not been provided. One manufacturer even promised medical effects of its products. There was no uniform general classification of products making it difficult to identify characteristics of cleansers and choose between them. Presently, there are no commonly accepted criteria to classify products in view of cleansing effectiveness und skin compatibility. Generally accepted criteria and test methods are needed for the evaluation of hand cleansers in order to provide the possibility of transparency and comparability. © The Authors • Journal compilation © Blackwell Verlag GmbH, Berlin.

ArrayBridge: Interweaving declarative array processing with high-performance computing

DOE Office of Scientific and Technical Information (OSTI.GOV)

Xing, Haoyuan; Floratos, Sofoklis; Blanas, Spyros

Scientists are increasingly turning to datacenter-scale computers to produce and analyze massive arrays. Despite decades of database research that extols the virtues of declarative query processing, scientists still write, debug and parallelize imperative HPC kernels even for the most mundane queries. This impedance mismatch has been partly attributed to the cumbersome data loading process; in response, the database community has proposed in situ mechanisms to access data in scientific file formats. Scientists, however, desire more than a passive access method that reads arrays from files. This paper describes ArrayBridge, a bi-directional array view mechanism for scientific file formats, that aimsmore » to make declarative array manipulations interoperable with imperative file-centric analyses. Our prototype implementation of ArrayBridge uses HDF5 as the underlying array storage library and seamlessly integrates into the SciDB open-source array database system. In addition to fast querying over external array objects, ArrayBridge produces arrays in the HDF5 file format just as easily as it can read from it. ArrayBridge also supports time travel queries from imperative kernels through the unmodified HDF5 API, and automatically deduplicates between array versions for space efficiency. Our extensive performance evaluation in NERSC, a large-scale scientific computing facility, shows that ArrayBridge exhibits statistically indistinguishable performance and I/O scalability to the native SciDB storage engine.« less

Friend or Ally? A Question for New Zealand

DTIC Science & Technology

1991-05-01

Many close observers of the manoeuvring which went on from the time the Lange government took power in July 1984 until George Shultz declared a...d s - - bu t we par t . George P. Shultz Manila, July 1986 ~ ITH THE WORDS, "we part," the Secretary of State for the United States of...the Western alliance. George Shultz’ simple words marked an historic turn- ing point in United States/New Zealand relations and, perhaps even more

The Nepalese Army in Internal Peace and Security

DTIC Science & Technology

2013-06-14

instead of milk leading to the death of the buffalo and cow ” (Baral 2012, 13). 43 Nepali is not the first language of the majority of the Nepalese...religious places. Baral states, “People in the villages would not even give milk to the Dalits because of the belief that [thereafter] blood would come...GoN itself is reluctant to promote diverse cultures and languages as it continues to declare Nepal a Hindu country. The cow , simrik (vermilion

On a simple attack, limiting the range transmission of secret keys in a system of quantum cryptography based on coding in a sub-carrier frequency

NASA Astrophysics Data System (ADS)

Klimov, A. N.; Kulik, S. P.; Molotkov, S. N.; Potapova, T. A.

2017-03-01

In the paper by Gleim et al (2016 Opt. Express 24 2619), it was declared that the system of quantum cryptography, exploiting quantum key distribution (QKD) protocol BB84 with the additional reference state and encoding in a sub-carrier, is able to distribute secret keys at a distance of 210 km. The following shows that a simple attack realized with a beam splitter results in a loss of privacy of the keys over substantially smaller distances. It turns out that the actual length of the secret key transmission for the QKD system encoding in the sub-carrier frequency is ten times less than that declared in Gleim et al (2016 Opt. Express 24 2619). Therefore it is impossible to safely use the keys when distributed at a larger length of the communication channel than shown below. The maximum communication distance does not exceed 22 km, even in the most optimistic scenario.

Preconscious defence analysis, memory and structural change.

PubMed

Ross, John Munder

2003-02-01

Beginning with the ways in which the use of the couch lends 'depth to the surface' (Erikson, 1954), I explore the topography of the inter- and intrasubjective psychoanalytic situation and process. I suggest that defences are not by definition unconscious but rather can be observed operating at conscious and preconscious levels, particularly under these conditions. A focus on preconscious disavowal provides a window on what has become unconscious repression. As a result of eliciting and then verbalising the operation of such defences with regard to anxieties in the here-and-now transference, declarative memories of increasingly specific childhood fantasies and events begin to hold sway over unmanageable procedural remnants from the analysand's past. With this may even come the possibility of neuronal regeneration, the more generalisable enhancement of declarative and symbolic functions and the sense of identity with which these are associated. Herein may lie one enduring therapeutic effect of the 'talking cure' - putting feelings into words - as one among a variety of psychotherapeutic modalities.

Lidar-revised geologic map of the Des Moines 7.5' quadrangle, King County, Washington

USGS Publications Warehouse

Tabor, Rowland W.; Booth, Derek B.

2017-11-06

This map is an interpretation of a modern lidar digital elevation model combined with the geology depicted on the Geologic Map of the Des Moines 7.5' Quadrangle, King County, Washington (Booth and Waldron, 2004). Booth and Waldron described, interpreted, and located the geology on the 1:24,000-scale topographic map of the Des Moines 7.5' quadrangle. The base map that they used was originally compiled in 1943 and revised using 1990 aerial photographs; it has 25-ft contours, nominal horizontal resolution of about 40 ft (12 m), and nominal mean vertical accuracy of about 10 ft (3 m). Similar to many geologic maps, much of the geology in the Booth and Waldron (2004) map was interpreted from landforms portrayed on the topographic map. In 2001, the Puget Sound Lidar Consortium obtained a lidar-derived digital elevation model (DEM) for much of the Puget Sound area, including the entire Des Moines 7.5' quadrangle. This new DEM has a horizontal resolution of about 6 ft (2 m) and a mean vertical accuracy of about 1 ft (0.3 m). The greater resolution and accuracy of the lidar DEM compared to topography constructed from air-photo stereo models have much improved the interpretation of geology, even in this heavily developed area, especially the distribution and relative age of some surficial deposits. For a brief description of the light detection and ranging (lidar) remote sensing method and this data acquisition program, see Haugerud and others (2003). 

Non-Declarative Sequence Learning does not Show Savings in Relearning

PubMed Central

Keisler, Aysha; Willingham, Daniel T.

2007-01-01

Researchers have utilized the savings in relearning paradigm in a variety of settings since Ebbinghaus developed the tool over a century ago. In spite of its widespread use, we do not yet understand what type(s) of memory are measurable by savings. Specifically, can savings measure both declarative and non-declarative memories? The lack of conscious recollection of the encoded material in some studies indicates that non-declarative memories may show savings effects, but as all studies to date have used declarative tasks, we cannot be certain. Here, we administer a non-declarative task and then measure savings in relearning the material declaratively. Our results show that while material outside of awareness may show savings effects, non-declarative sequence memory does not. These data highlight the important distinction between memory without awareness and non-declarative memory. PMID:17343944

Non-declarative sequence learning does not show savings in relearning.

PubMed

Keisler, Aysha; Willingham, Daniel T

2007-04-01

Researchers have utilized the savings in relearning paradigm in a variety of settings since Ebbinghaus developed the tool over a century ago. In spite of its widespread use, we do not yet understand what type(s) of memory are measurable by savings. Specifically, can savings measure both declarative and non-declarative memories? The lack of conscious recollection of the encoded material in some studies indicates that non-declarative memories may show savings effects, but as all studies to date have used declarative tasks, we cannot be certain. Here, we administer a non-declarative task and then measure savings in relearning the material declaratively. Our results show that while material outside of awareness may show savings effects, non-declarative sequence memory does not. These data highlight the important distinction between memory without awareness and non-declarative memory.

Schizophrenia patients demonstrate a dissociation on declarative and non-declarative memory tests.

PubMed

Perry, W; Light, G A; Davis, H; Braff, D L

2000-12-15

Declarative memory refers to the recall and recognition of factual information. In contrast, non-declarative memory entails a facilitation of memory based on prior exposure and is typically assessed with priming and perceptual-motor sequencing tasks. In this study, schizophrenia patients were compared to normal comparison subjects on two computerized memory tasks: the Word-stem Priming Test (n=30) and the Pattern Sequence Learning Test (n=20). Word-stem Priming includes recall, recognition (declarative) and priming (non-declarative) components of memory. The schizophrenia patients demonstrated an impaired performance on recall of words with relative improvement during the recognition portion of the test. Furthermore, they performed normally on the priming portion of the test. Thus, on tests of declarative memory, the patients had retrieval deficits with intact performance on the non-declarative memory component. The Pattern Sequence Learning Test utilizes a serial reaction time paradigm to assess non-declarative memory. The schizophrenia patients' serial reaction time was significantly slower than that of comparison subjects. However, the patients' rate of acquisition was not different from the normal comparison group. The data suggest that patients with schizophrenia process more slowly than normal, but have an intact non-declarative memory. The schizophrenia patients' dissociation on declarative vs. non-declarative memory tests is discussed in terms of possible underlying structural impairment.

Impact of Dry Eye Syndrome on Vision-Related Quality of Life in a Non-Clinic-Based General Population

PubMed Central

2012-01-01

Background Dry eye syndrome (DES) is a common ocular disorder occurring in general population. The purpose of this study is to evaluate the impact of DES on vision-related quality of life (QoL) in a non-clinic-based general population. Methods This population-based cross-sectional study enrolled subjects older than 40 years, who took part in an epidemiological study on dry eye in Sanle Community, Shanghai. Apart from the collection of sociodemographics, dry eye symptoms, and other clinical data, a Chinese version of the 25-item National Eye Institute Visual Functioning Questionnaire (NEI VFQ-25) was administered to all subjects. Comparisons of the NEI VFQ-25 subscale item scores and composite score were made among subgroups divided according to the presence of dry eye symptoms or signs. Multivariate regression analysis was performed to investigate the relationship between the clinical variables and the VFQ-25 composite score. Results A total of 229 participants were enrolled in the study, with an average age of (60.7 ±10.1) years old. Majority of these participants were female (59.8 %, 137/229). The total DES symptom scores (TDSS) in subjects either with definite DES or only with dry eye symptoms were significantly higher (F = 60.331, P < 0.001). The values of tear break-up time (TBUT) and Schirmer test were significantly lower in participants with DES and those with dry eye signs only (F = 55.158 and 40.778, P < 0.001). The composite score of the NEI VFQ-25 was significantly lower in subjects with DES (F = 4.901, P = 0.003). Moreover, the subscale scores of ocular pain and mental health were significantly lower in those with either DES or dry eye symptoms only (F = 10.962 and 7.362 respectively, both P < 0.001). The multiple regression analysis showed that the TDSS had a significant negative correlation with the VFQ-25 composite score as well as with the subscale score for ocular pain and mental health, even after the adjustment of all other factors (all P < 0.01). Conclusions The symptoms of dry eye are associated with an adverse impact on vision-related QoL in non-clinic-based general population, which is mainly represented as more ocular pain and discomfort, and impaired mental health as well. Apart from clinical examination, it is also important to refer to subjective symptoms and QoL scores when assessing the severity of DES. PMID:22799274

The Historical Significance of the Universal Declaration.

ERIC Educational Resources Information Center

Eide, Asbjorn

1998-01-01

Explains the historical significance of the Universal Declaration of Human Rights. Focuses on the initiative for the Declaration and its elaboration, the precursors to modern human rights, the foundation of the Declaration, the rights contained in the Universal Declaration, three modes of human rights analysis, and global governance and human…

19 CFR 148.18 - Failure to declare.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 19 Customs Duties 2 2013-04-01 2013-04-01 false Failure to declare. 148.18 Section 148.18 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF THE TREASURY (CONTINUED) PERSONAL DECLARATIONS AND EXEMPTIONS Declarations § 148.18 Failure to declare. (a) Penalty...

19 CFR 148.18 - Failure to declare.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 19 Customs Duties 2 2011-04-01 2011-04-01 false Failure to declare. 148.18 Section 148.18 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF THE TREASURY (CONTINUED) PERSONAL DECLARATIONS AND EXEMPTIONS Declarations § 148.18 Failure to declare. (a) Penalty...

19 CFR 148.18 - Failure to declare.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 19 Customs Duties 2 2014-04-01 2014-04-01 false Failure to declare. 148.18 Section 148.18 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF THE TREASURY (CONTINUED) PERSONAL DECLARATIONS AND EXEMPTIONS Declarations § 148.18 Failure to declare. (a) Penalty...

19 CFR 148.18 - Failure to declare.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 19 Customs Duties 2 2010-04-01 2010-04-01 false Failure to declare. 148.18 Section 148.18 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF THE TREASURY (CONTINUED) PERSONAL DECLARATIONS AND EXEMPTIONS Declarations § 148.18 Failure to declare. (a) Penalty...

19 CFR 148.18 - Failure to declare.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 19 Customs Duties 2 2012-04-01 2012-04-01 false Failure to declare. 148.18 Section 148.18 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF THE TREASURY (CONTINUED) PERSONAL DECLARATIONS AND EXEMPTIONS Declarations § 148.18 Failure to declare. (a) Penalty...

Strategic Rescue: Vectoring Airpower Advocates to Embrace the Real Value of Personnel Recovery

DTIC Science & Technology

2011-01-01

world as beacons of freedom, if they know that their country will support them. This is just one reason that we conduct PR. To an even greater degree...A selective look at the long history of the United States’ PR operations is revealing. Search and rescue operations during the Vietnam War were a...declaring that a Soldier will never leave a fallen comrade and that an Airman will never leave an- other Airman behind. Dr. Earl Tilford, a noted

What records have we been breaking?

USGS Publications Warehouse

Bartholow, J.M.; Milhous, R.

2002-01-01

"Today was another record-breaking day," the evening radio or television declares. High temperatures, low temperatures, floods, drought - take your choice. But how can we put these pronouncements in perspective? What do they really mean?We present two types of information in this article: 1) an analysis of daily air temperature and precipitation for Fort Collins and 2) an analysis of annual precipitation for Fort Collins. Each analysis provides a different meaning to the statement about a record-breaking day or year.

Reinvestment and recovery

PubMed Central

Epstein, Jonathan A.

2009-01-01

When US President Barack Obama declared in his 2009 inaugural address, “We will restore science to its rightful place,” many applauded. The US has led the world in research, innovation, and education in the medical sciences. The National Science Foundation, the NIH, and other government organizations involved in scientific investigations are the primary engines that have fueled this excellence over the past half century. Nevertheless, we cannot afford to assume that preeminence, or even excellence, will persist without attention and cultivation. PMID:19487815

37 CFR 1.69 - Foreign language oaths and declarations.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 37 Patents, Trademarks, and Copyrights 1 2011-07-01 2011-07-01 false Foreign language oaths and... Declaration § 1.69 Foreign language oaths and declarations. (a) Whenever an individual making an oath or declaration cannot understand English, the oath or declaration must be in a language that such individual can...

37 CFR 1.69 - Foreign language oaths and declarations.

Code of Federal Regulations, 2010 CFR

2010-07-01

... declaration cannot understand English, the oath or declaration must be in a language that such individual can... declaration relates. (b) Unless the text of any oath or declaration in a language other than English is in a... accompanied by an English translation together with a statement that the translation is accurate, except that...

A shared resource between declarative memory and motor memory

PubMed Central

Keisler, Aysha; Shadmehr, Reza

2010-01-01

The neural systems that support motor adaptation in humans are thought to be distinct from those that support the declarative system. Yet, during motor adaptation changes in motor commands are supported by a fast adaptive process that has important properties (rapid learning, fast decay) that are usually associated with the declarative system. The fast process can be contrasted to a slow adaptive process that also supports motor memory, but learns gradually and shows resistance to forgetting. Here we show that after people stop performing a motor task, the fast motor memory can be disrupted by a task that engages declarative memory, but the slow motor memory is immune from this interference. Furthermore, we find that the fast/declarative component plays a major role in the consolidation of the slow motor memory. Because of the competitive nature of declarative and non-declarative memory during consolidation, impairment of the fast/declarative component leads to improvements in the slow/non-declarative component. Therefore, the fast process that supports formation of motor memory is not only neurally distinct from the slow process, but it shares critical resources with the declarative memory system. PMID:21048140

26 CFR 301.6316-6 - Declarations of estimated tax.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 26 Internal Revenue 18 2010-04-01 2010-04-01 false Declarations of estimated tax. 301.6316-6... Declarations of estimated tax. (a) Filing of declaration. A declaration of estimated tax in respect of amounts on which the tax is to be paid in foreign currency under the provisions of § 301.6316-1 shall be...

Cognitive foundations of organizational learning: re-introducing the distinction between declarative and non-declarative knowledge

PubMed Central

Kump, Barbara; Moskaliuk, Johannes; Cress, Ulrike; Kimmerle, Joachim

2015-01-01

Contemporary research into socio-cognitive foundations of organizational learning tends to disregard the distinction between declarative and non-declarative knowledge. By reviewing the literature from organizational learning research and cognitive psychology we explain that this distinction is crucial. We describe the foundations of organizational learning by referring to models that consider the interplay between individual and collective knowledge-related processes in organizations. We highlight the existence of a research gap resulting from the finding that these approaches have widely neglected the existence of different types of knowledge. We then elaborate on characteristics of declarative and non-declarative knowledge in general, consider organizations as structures of distributed cognition, and discuss the relationship between organizational knowledge and practice. Subsequently, we examine the role of declarative and non-declarative knowledge in the context of organizational learning. Here, we analyze (1) the cognitive and social mechanisms underlying the development of declarative and non-declarative knowledge within structures of distributed cognition; and (2) the relationship between alterations in declarative and non-declarative types of knowledge on the one hand and changes in organizational practice on the other. Concluding, we discuss implications of our analysis for organizational learning research. We explain how our integrative perspective may offer starting points for a refined understanding of the sub-processes involved in organizational learning and unlearning and may support a better understanding of practical problems related to organizational learning and change. PMID:26483739

Does the cholinesterase inhibitor, donepezil, benefit both declarative and non-declarative processes in mild to moderate Alzheimer's disease?

PubMed

Winstein, Carolee J; Bentzen, Kirk R; Boyd, Lara; Schneider, Lon S

2007-07-01

Previous research suggests separate neural networks for implicit (non-declarative) and explicit (declarative) memory processes. A core cognitive impairment in mild to moderate Alzheimer's disease (AD) is a pronounced declarative memory and learning deficit with relative preservation of non-declarative memory. Cholinesterase inhibitors has been purported to enhance cognitive function, and previous clinical trials consistently showed that donepezil, a reversible inhibitor of acetylcholinesterase (AChE), led to statistically significant improvements in cognition and patient function. This prospective pilot study is a randomized, double blind, placebo-controlled clinical trial investigating 10 patients with AD. Our purpose was to examine the relationship between declarative and non-declarative capability with particular emphasis on implicit sequence learning. Patients were assessed at baseline and again at 4-weeks. After participants' baseline data were obtained, each was double-blindly randomized to one of two groups: donepezil or placebo. At baseline participants were tested with two outcome measures (Serial Reaction Time Task, Alzheimer's Disease Assessment Scale-Cognitive Subscale). Participants were given either 5 mg donepezil or an identically appearing placebo to be taken nightly for 4 weeks (28 tablets), and then retested. The donepezil group demonstrated a greater likelihood of increases in both non-declarative and declarative processes. The placebo group was mixed without clearly definable trends or patterns. When the data were examined for coincidental changes in the two outcome measures together they are suggestive of a benefit from donepezil treatment for non-declarative and declarative processes.

Algebraic Structure of Dynamical Systems

DTIC Science & Technology

2017-05-22

to suggest that the mathematics performed in this research will have such profound 10 implications, but just to demonstrate that studying math for...the sake of studying math can often reveal much about the world, even if not immediately obvious. Throughout the paper, we prove the following three...Banach and Alfred Tarski. Sur la décomposition des ensembles de points en parties respectivement congruentes. Fund. math , 6(1924):244–277, 1924. [3

Missile Aerodynamics (Aerodynamique des Missiles)

DTIC Science & Technology

1998-11-01

Magnus effect. effects on a spinning finned cylindrical body. Despite the large As noted above, the source, magnitude and even the direction amount of...axis, and to circular- cylindrical bodies in combination with determine directly the pressures acting on the body. triangular, rectangular, or...pressure drop in smooth cylindrical codes, as well as for testing and checking CFD-based tubes", NACA ARR L4C16, 1944. results. 6. Nielsen, J. N. and

Evaluation of the Navys Sea/Shore Flow Policy

DTIC Science & Technology

2016-06-01

Std. Z39.18 i Abstract CNA developed an independent Discrete -Event Simulation model to evaluate and assess the effect of...a more steady manning level, but the variability remains, even if the system is optimized. In building a Discrete -Event Simulation model, we...steady-state model. In FY 2014, CNA developed a Discrete -Event Simulation model to evaluate the impact of sea/shore flow policy (the DES-SSF model

Speech Intelligibility and Prosody Production in Children with Cochlear Implants

PubMed Central

Chin, Steven B.; Bergeson, Tonya R.; Phan, Jennifer

2012-01-01

Objectives The purpose of the current study was to examine the relation between speech intelligibility and prosody production in children who use cochlear implants. Methods The Beginner's Intelligibility Test (BIT) and Prosodic Utterance Production (PUP) task were administered to 15 children who use cochlear implants and 10 children with normal hearing. Adult listeners with normal hearing judged the intelligibility of the words in the BIT sentences, identified the PUP sentences as one of four grammatical or emotional moods (i.e., declarative, interrogative, happy, or sad), and rated the PUP sentences according to how well they thought the child conveyed the designated mood. Results Percent correct scores were higher for intelligibility than for prosody and higher for children with normal hearing than for children with cochlear implants. Declarative sentences were most readily identified and received the highest ratings by adult listeners; interrogative sentences were least readily identified and received the lowest ratings. Correlations between intelligibility and all mood identification and rating scores except declarative were not significant. Discussion The findings suggest that the development of speech intelligibility progresses ahead of prosody in both children with cochlear implants and children with normal hearing; however, children with normal hearing still perform better than children with cochlear implants on measures of intelligibility and prosody even after accounting for hearing age. Problems with interrogative intonation may be related to more general restrictions on rising intonation, and the correlation results indicate that intelligibility and sentence intonation may be relatively dissociated at these ages. PMID:22717120

After Being Challenged by a Video Game Problem, Sleep Increases the Chance to Solve It

PubMed Central

Beijamini, Felipe; Pereira, Sofia Isabel Ribeiro; Cini, Felipe Augusto; Louzada, Fernando Mazzilli

2014-01-01

In the past years many studies have demonstrated the role of sleep on memory consolidation. It is known that sleeping after learning a declarative or non-declarative task, is better than remaining awake. Furthermore, there are reports of a possible role for dreams in consolidation of declarative memories. Other studies have reported the effect of naps on memory consolidation. With similar protocols, another set of studies indicated that sleep has a role in creativity and problem-solving. Here we hypothesised that sleep can increase the likelihood of solving problems. After struggling to solve a video game problem, subjects who took a nap (n = 14) were almost twice as likely to solve it when compared to the wake control group (n = 15). It is interesting to note that, in the nap group 9 out 14 subjects engaged in slow-wave sleep (SWS) and all solved the problem. Surprisingly, we did not find a significant involvement of Rapid Eye Movement (REM) sleep in this task. Slow-wave sleep is believed to be crucial for the transfer of memory-related information to the neocortex and implement intentions. Sleep can benefit problem-solving through the generalisation of newly encoded information and abstraction of the gist. In conclusion, our results indicate that sleep, even a nap, can potentiate the solution of problems that involve logical reasoning. Thus, sleep's function seems to go beyond memory consolidation to include managing of everyday-life events. PMID:24416219

After being challenged by a video game problem, sleep increases the chance to solve it.

PubMed

Beijamini, Felipe; Pereira, Sofia Isabel Ribeiro; Cini, Felipe Augusto; Louzada, Fernando Mazzilli

2014-01-01

In the past years many studies have demonstrated the role of sleep on memory consolidation. It is known that sleeping after learning a declarative or non-declarative task, is better than remaining awake. Furthermore, there are reports of a possible role for dreams in consolidation of declarative memories. Other studies have reported the effect of naps on memory consolidation. With similar protocols, another set of studies indicated that sleep has a role in creativity and problem-solving. Here we hypothesised that sleep can increase the likelihood of solving problems. After struggling to solve a video game problem, subjects who took a nap (n = 14) were almost twice as likely to solve it when compared to the wake control group (n = 15). It is interesting to note that, in the nap group 9 out 14 subjects engaged in slow-wave sleep (SWS) and all solved the problem. Surprisingly, we did not find a significant involvement of Rapid Eye Movement (REM) sleep in this task. Slow-wave sleep is believed to be crucial for the transfer of memory-related information to the neocortex and implement intentions. Sleep can benefit problem-solving through the generalisation of newly encoded information and abstraction of the gist. In conclusion, our results indicate that sleep, even a nap, can potentiate the solution of problems that involve logical reasoning. Thus, sleep's function seems to go beyond memory consolidation to include managing of everyday-life events.

Knowledge, attitudes, representations and declared practices of nurses and physicians about obesity in a university hospital: training is essential.

PubMed

Bucher Della Torre, S; Courvoisier, D S; Saldarriaga, A; Martin, X E; Farpour-Lambert, N J

2018-04-01

In the context of a worldwide obesity epidemic, healthcare providers play a key role in obesity management. Knowledge of current guidelines and attitudes to prevent stigmatization are especially important. This study aimed to assess knowledge, attitudes, beliefs, perception of opportunity for intervention, declared practices and need for training and material of nurses and physicians about obesity in a Swiss University Hospital. A total of 834 physicians and nurses filled an online survey. The questionnaire was based on literature, exploratory interviews and expert committee review. It was pre-tested with 15 physicians and nurses. Participants declared a low level of negative attitudes towards individuals living with obesity. However, the results highlighted a lack of knowledge to diagnose obesity in adults and children, as well as confidence and training to care of patients with obesity. One-third of providers did not know how to calculate body mass index. Half of providers felt it was part of their role to take care of patients with obesity, even if 55% of them had the feeling that they did not have adequate training. Nurses and physicians working in a university hospital showed a low level of negative attitudes but a lack of knowledge and skills on obesity management. Training should be improved in this population to insure adequate and coherent messages and equal access to evidence-based treatment for patients living with obesity. © 2018 World Obesity Federation.

15 CFR 714.3 - Advance declaration requirements for additionally planned production of Schedule 3 chemicals.

Code of Federal Regulations, 2013 CFR

2013-01-01

... a Schedule 3 chemical above the declaration threshold; (ii) You plan to produce at a plant declared...; (iii) You plan to increase the production of a Schedule 3 chemical by declared plants on your plant... production of a Schedule 3 chemical at a declared plant site to an amount above the upper limit of the range...

15 CFR 714.3 - Advance declaration requirements for additionally planned production of Schedule 3 chemicals.

Code of Federal Regulations, 2012 CFR

2012-01-01

... a Schedule 3 chemical above the declaration threshold; (ii) You plan to produce at a plant declared...; (iii) You plan to increase the production of a Schedule 3 chemical by declared plants on your plant... production of a Schedule 3 chemical at a declared plant site to an amount above the upper limit of the range...

15 CFR 714.3 - Advance declaration requirements for additionally planned production of Schedule 3 chemicals.

Code of Federal Regulations, 2014 CFR

2014-01-01

... a Schedule 3 chemical above the declaration threshold; (ii) You plan to produce at a plant declared...; (iii) You plan to increase the production of a Schedule 3 chemical by declared plants on your plant... production of a Schedule 3 chemical at a declared plant site to an amount above the upper limit of the range...

Dark Energy Survey Year 1 Results: Cross-Correlation Redshifts in the DES -- Calibration of the Weak Lensing Source Redshift Distributions

DOE Office of Scientific and Technical Information (OSTI.GOV)

Davis, C.; et al.

We present the calibration of the Dark Energy Survey Year 1 (DES Y1) weak lensing source galaxy redshift distributions from clustering measurements. By cross-correlating the positions of source galaxies with luminous red galaxies selected by the redMaGiC algorithm we measure the redshift distributions of the source galaxies as placed into different tomographic bins. These measurements constrain any such shifts to an accuracy ofmore » $$\\sim0.02$$ and can be computed even when the clustering measurements do not span the full redshift range. The highest-redshift source bin is not constrained by the clustering measurements because of the minimal redshift overlap with the redMaGiC galaxies. We compare our constraints with those obtained from $$\\texttt{COSMOS}$$ 30-band photometry and find that our two very different methods produce consistent constraints.« less

Searching for modified growth patterns with tomographic surveys

NASA Astrophysics Data System (ADS)

Zhao, Gong-Bo; Pogosian, Levon; Silvestri, Alessandra; Zylberberg, Joel

2009-04-01

In alternative theories of gravity, designed to produce cosmic acceleration at the current epoch, the growth of large scale structure can be modified. We study the potential of upcoming and future tomographic surveys such as Dark Energy Survey (DES) and Large Synoptic Survey Telescope (LSST), with the aid of cosmic microwave background (CMB) and supernovae data, to detect departures from the growth of cosmic structure expected within general relativity. We employ parametric forms to quantify the potential time- and scale-dependent variation of the effective gravitational constant and the differences between the two Newtonian potentials. We then apply the Fisher matrix technique to forecast the errors on the modified growth parameters from galaxy clustering, weak lensing, CMB, and their cross correlations across multiple photometric redshift bins. We find that even with conservative assumptions about the data, DES will produce nontrivial constraints on modified growth and that LSST will do significantly better.

Trends in Compulsory Licensing of Pharmaceuticals Since the Doha Declaration: A Database Analysis

PubMed Central

Beall, Reed; Kuhn, Randall

2012-01-01

Background It is now a decade since the World Trade Organization (WTO) adopted the “Declaration on the TRIPS Agreement and Public Health” at its 4th Ministerial Conference in Doha. Many anticipated that these actions would lead nations to claim compulsory licenses (CLs) for pharmaceutical products with greater regularity. A CL is the use of a patented innovation that has been licensed by a state without the permission of the patent title holder. Skeptics doubted that many CLs would occur, given political pressure against CL activity and continued health system weakness in poor countries. The subsequent decade has seen little systematic assessment of the Doha Declaration's impact. Methods and Findings We assembled a database of all episodes in which a CL was publically entertained or announced by a WTO member state since 1995. Broad searches of CL activity were conducted using media, academic, and legal databases, yielding 34 potential CL episodes in 26 countries. Country- and product-specific searches were used to verify government participation, resulting in a final database of 24 verified CLs in 17 nations. We coded CL episodes in terms of outcome, national income, and disease group over three distinct periods of CL activity. Most CL episodes occurred between 2003 and 2005, involved drugs for HIV/AIDS, and occurred in upper-middle-income countries (UMICs). Aside from HIV/AIDS, few CL episodes involved communicable disease, and none occurred in least-developed or low-income countries. Conclusions Given skepticism about the Doha Declaration's likely impact, we note the relatively high occurrence of CLs, yet CL activity has diminished markedly since 2006. While UMICs have high CL activity and strong incentives to use CLs compared to other countries, we note considerable countervailing pressures against CL use even in UMICs. We conclude that there is a low probability of continued CL activity. We highlight the need for further systematic evaluation of global health governance actions. Please see later in the article for the Editors' Summary PMID:22253577

Trends in compulsory licensing of pharmaceuticals since the Doha Declaration: a database analysis.

PubMed

Beall, Reed; Kuhn, Randall

2012-01-01

It is now a decade since the World Trade Organization (WTO) adopted the "Declaration on the TRIPS Agreement and Public Health" at its 4th Ministerial Conference in Doha. Many anticipated that these actions would lead nations to claim compulsory licenses (CLs) for pharmaceutical products with greater regularity. A CL is the use of a patented innovation that has been licensed by a state without the permission of the patent title holder. Skeptics doubted that many CLs would occur, given political pressure against CL activity and continued health system weakness in poor countries. The subsequent decade has seen little systematic assessment of the Doha Declaration's impact. We assembled a database of all episodes in which a CL was publically entertained or announced by a WTO member state since 1995. Broad searches of CL activity were conducted using media, academic, and legal databases, yielding 34 potential CL episodes in 26 countries. Country- and product-specific searches were used to verify government participation, resulting in a final database of 24 verified CLs in 17 nations. We coded CL episodes in terms of outcome, national income, and disease group over three distinct periods of CL activity. Most CL episodes occurred between 2003 and 2005, involved drugs for HIV/AIDS, and occurred in upper-middle-income countries (UMICs). Aside from HIV/AIDS, few CL episodes involved communicable disease, and none occurred in least-developed or low-income countries. Given skepticism about the Doha Declaration's likely impact, we note the relatively high occurrence of CLs, yet CL activity has diminished markedly since 2006. While UMICs have high CL activity and strong incentives to use CLs compared to other countries, we note considerable countervailing pressures against CL use even in UMICs. We conclude that there is a low probability of continued CL activity. We highlight the need for further systematic evaluation of global health governance actions. Please see later in the article for the Editors' Summary.

Central Nervous Insulin Signaling in Sleep-Associated Memory Formation and Neuroendocrine Regulation.

PubMed

Feld, Gordon B; Wilhem, Ines; Benedict, Christian; Rüdel, Benjamin; Klameth, Corinna; Born, Jan; Hallschmid, Manfred

2016-05-01

The neurochemical underpinnings of sleep's contribution to the establishment and maintenance of memory traces are largely unexplored. Considering that intranasal insulin administration to the CNS improves memory functions in healthy and memory-impaired humans, we tested whether brain insulin signaling and sleep interact to enhance memory consolidation in healthy participants. We investigated the effect of intranasal insulin on sleep-associated neurophysiological and neuroendocrine parameters and memory consolidation in 16 men and 16 women (aged 18-30 years), who learned a declarative word-pair task and a procedural finger sequence tapping task in the evening before intranasal insulin (160 IU) or placebo administration and 8 h of nocturnal sleep. On the subsequent evening, they learned interfering word-pairs and a new finger sequence before retrieving the original memories. Insulin increased growth hormone concentrations in the first night-half and EEG delta power during the second 90 min of non-rapid-eye-movement sleep. Insulin treatment impaired the acquisition of new contents in both the declarative and procedural memory systems on the next day, whereas retrieval of original memories was unchanged. Results indicate that sleep-associated memory consolidation is not a primary mediator of insulin's acute memory-improving effect, but that the peptide acts on mechanisms that diminish the subsequent encoding of novel information. Thus, by inhibiting processes of active forgetting during sleep, central nervous insulin might reduce the interfering influence of encoding new information.

Developmental Dissociation Between the Maturation of Procedural Memory and Declarative Memory

PubMed Central

Finn, Amy S.; Kalra, Priya B.; Goetz, Calvin; Leonard, Julia A.; Sheridan, Margaret A.; Gabrieli, John D. E.

2015-01-01

Declarative memory and procedural memory are known to be two fundamentally different kinds of memory that are dissociable in their psychological characteristics and measurement (explicit versus implicit) and in the neural systems that subserve each kind of memory. Declarative memory abilities are known to improve from childhood through young adulthood, but the developmental maturation of procedural memory is largely unknown. We compared 10-year-old children and young adults on measures of declarative memory, working memory capacity, and four measures of procedural memory that have been strongly dissociated from declarative memory (mirror tracing, rotary pursuit, probabilistic classification, and artificial grammar). Children had lesser declarative memory ability and lesser working memory capacity than the adults, but exhibited learning equivalent to adults on all four measures of procedural memory. Declarative and procedural memory are, therefore, developmentally dissociable, with procedural memory being adult-like by age 10 and declarative memory continuing to mature into young adulthood. PMID:26560675

John Porter Book Prize Lecture: Bringing the Social Back In-On the Integration of Muslim Immigrants and the Jurisprudence of Muslim Minorities.

PubMed

Kazemipur, Abdolmohammad

2016-11-01

In much of the academic debate on the integration of Muslims into Western liberal democracies, Islam is often treated as one or the sole independent variable in the lives of Muslims. Offering to view Islam-or the understanding of Islam among Muslims-as the dependent variable, The Muslim Question in Canada discusses the influence of socioeconomic forces in shaping the Muslim immigrants' opinions, modes of thinking, and even interpretations of their faith. Drawing on this general approach, which is introduced and developed in the book using a variety of both quantitative and qualitative data, this article focuses on a school of thought within the Islamic jurisprudence known as fiqh al-aqalliyyat al-Muslema (the jurisprudence of Muslim minorities). The premise of the jurisprudence of Muslim minorities is that the lived realities of Muslims who reside in non-Muslim countries are so fundamentally different from those of the Muslim-majority nations that traditional Islamic jurisprudence cannot offer meaningful solutions for their problems. Therefore, there is a need to establish an entirely different jurisprudential approach centered around the lives of the Muslim minorities. The purpose of the bulk of jurisprudential theorization efforts in this line of reasoning is to facilitate the lives of the Muslim minorities; as well, they aim to create a foundation for the moral obligations of Muslims toward non-Muslims in such environments. I argue that a crucial element that triggers such a development is the existence of a positive relationship between Muslims and non-Muslims in immigrant-receiving countries. Souvent au sein des débats sur l'intégration des Musulmans dans des démocraties libérales de l'Ouest, l'Islam est traité comme un ou le seul enjeu dans la vie des fidèles. The Muslim Question in Canada examine l'Islam ou la compréhension de l'Islam chez les Musulmans comme un enjeu dépendent et aborde l'influence des forces socio-économiques sur les opinons des immigrants musulmans ainsi que sur leurs modes de pensée et même sur la manière dont ils interprètent leur foi. Inspiré par cette approche, que l'on présente et développe dans le livre, et qui se sert de données à la fois quantitatives et qualitatives, cet article se concentre sur une école de pensée à l'intérieur de la jurisprudence islamique, connue sous le nom de fiqh al aqalliyyat al-Muslema (la jurisprudence des minorités musulmanes). La prémisse de la jurisprudence des minorités musulmanes est que les réalités vécues par les Musulmans qui vivent dans des pays non-musulmans sont au fond tellement différentes de celles de la majorité musulmane que la jurisprudence traditionnelle ne présente pas de solutions pertinentes pour résoudre leurs problèmes. Ainsi, il faut établir une approche jurisprudentielle totalement différente, axée sur la vie des minorités musulmanes. L'objectif de la plupart des efforts au niveau de la théorisation de la jurisprudence qui adoptent cette vision est de rendre la vie des minorités musulmanes plus facile. Ces efforts tentent aussi de faire en sorte que les Musulmans ressentent une certaine obligation morale envers les non-Musulmans dans ces environnements. J'avance ici que l'aspect qui déclenche un tel développement est le rapport positif entre les Musulmans et les non-Musulmans dans les pays qui reçoivent des immigrants. © 2016 Canadian Sociological Association/La Société canadienne de sociologie.

The nature of declarative and nondeclarative knowledge for implicit and explicit learning.

PubMed

Kirkhart, M W

2001-10-01

Using traditional implicit and explicit artificial-grammar learning tasks, the author investigated the similarities and differences between the acquisition of declarative knowledge under implicit and explicit learning conditions and the functions of the declarative knowledge during testing. Results suggested that declarative knowledge was not predictive of or required for implicit learning but was related to consistency in implicit learning performance. In contrast, declarative knowledge was predictive of and required for explicit learning and was related to consistency in performance. For explicit learning, the declarative knowledge functioned as a guide for other behavior. In contrast, for implicit learning, the declarative knowledge did not serve as a guide for behavior but was instead a post hoc description of the most commonly seen stimuli.

Two-Year Clinical Outcomes of Newer-Generation Drug-Eluting Stent Implantation Following Rotational Atherectomy for Heavily Calcified Lesions.

PubMed

Jinnouchi, Hiroyuki; Kuramitsu, Shoichi; Shinozaki, Tomohiro; Kobayashi, Yohei; Hiromasa, Takashi; Morinaga, Takashi; Mazaki, Toru; Sakakura, Kenichi; Soga, Yoshimitsu; Hyodo, Makoto; Shirai, Shinichi; Ando, Kenji

2015-01-01

Clinical outcomes of implantation of the newer-generation drug-eluting stent (DES) following rotational atherectomy for heavily calcified lesions remain unclear in the real-world setting. We enrolled 252 consecutive patients (273 lesions) treated with newer-generation DES following rotational atherectomy. The primary endpoint was the cumulative 2-year incidence of major adverse cardiovascular events (MACE), defined as cardiac death, myocardial infarction, clinically-driven target lesion revascularization, and definite stent thrombosis. Complete clinical follow-up information at 2-year was obtained for all patients. The mean age was 73.2±9.0 years and 155 patients (61.5%) were male. Cumulative 2-year incidence of MACE (cardiac death, myocardial infarction, clinically-driven target lesion revascularization and definite stent thrombosis) was 20.3% (7.0%, 2.1%, 18.1% and 2.1%, respectively). Predictors of MACE were presenting with acute coronary syndrome (hazard ratio [HR]: 3.80, 95% confidence interval [CI]: 1.29-11.2, P=0.02), hemodialysis (HR: 1.93, 95% CI: 1.04-3.56, P=0.04) and previous coronary artery bypass graft (HR: 2.26, 95% CI: 1.02-5.00, P=0.045). PCI for calcified lesions requiring rotational atherectomy is still challenging even in the era of newer-generation DES.

The effect of somatostatin analogs on secretion of growth, pancreatic, and gastrointestinal hormones in man.

PubMed

Adrian, T E; Barnes, A J; Long, R G; O'Shaughnessy, D J; Brown, M R; Rivier, J; Vale, W; Blackburn, A M; Bloom, S R

1981-10-01

The potency and specificity of somatostatin (SS) and four of its analogs were compared in seven patients with pancreatic endocrine tumors. The analogs tested were [D-Trp8]-SS, [D-Trp8, D-Cys14]-SS, Des-Asn5-[D-Trp8, D-Ser13]-SS, and Des (AA)1,2,4,5,12,13, [D-Trp8]-SS, and they did not show selective effects on the suppression of basal concentrations of GH, insulin, glucagon, pancreatic polypeptide, gastrin, gastric inhibitory peptide, motilin, enteroglucagon, or neurotensin. The observation that the potency of these analogs is similar to that of the parent molecule throws considerable light on the structure/activity relationship of the somatostatin molecule. Des-AA1,2,4,5,12,13, [D-Trp8]-Ss has been reported to have a prolonged action when administered sc. When administered iv, however, this octapeptide analog ws not long acting, suggesting that the prolonged action seen in the previous study was a result of delayed uptake from the injection site. An increment in plasma SS concentrations of 19 +/- 3 pmol/liter suppressed basal concentrations of GH, insulin, glucagon, and several gastrointestinal hormones by more than 50%, suggesting that even small changes in plasma SS levels may be physiologically important.

ACHP | The United Nations Declaration on the Rights of Indigenous Peoples

Science.gov Websites

March 1, 2013, the ACHP took a bold step to adopt a plan to support the U.N. Declaration. One of the commitments in the plan is to inform the historic preservation community about the Declaration. Therefore, we announcing ACHP plan to support the Declaration ACHP Plan to Support the U.N. Declaration on the Rights of

Études par diffraction haute résolution et réflectivité de films minces épitaxiés

NASA Astrophysics Data System (ADS)

Baulès, P.; Casanove, M. J.; Roucau, C.; Ousset, J. C.; Bobo, J. F.; Snoeck, E.; Magnoux, D.; Gatel, C.

2002-07-01

The studies we present concern the general researches involved in order to understand the growth mechanisms of thin films deposited on oriented substrates. Among the different investigation technics of the thin layers, X-ray diffraction and reflectivity will be discussed through two applications. In a first step, thediffraction presented, illustrated by reciprocal space mapping, will give information about the layer state of stress and the lattice distorsion of La{1-x}SrxMnO3 deposited on SrTiO3. The results obtained are discussed and compared to those given by electron microscopy. In a second step, we will present an application of reflectivity concerning a very roughness surface of platinum deposited on MgO showing an island growth process. We will verify that reflectivity can lead to the determination of the recovered rate of the surface, even if some problems exist in the simulation of the whole data set. Results obtained in electron microscopy will complete those issued from reflectivity. Les études que nous allons présenter sont à replacer dans le contexte général de la compréhension des mécanismes de croissance des films minces déposés sur des substrats orientés. Parmi les diverses techniques d'investigations des couches minces, la diffraction et la réflectivité des rayons X vont être abordées à travers deux applications. Nous verrons tout d'abord que la diffraction, illustrée par la cartographie en deux dimension du réseau réciproque, permet de remonter à l'état de contrainte ainsi qu'à la déformation de la maille de La{1-x}SrxMnO3 déposé sur SrTiO3. Les résultats déduits de ces mesures seront discutés et comparés à ceux obtenus en microscopie électronique. Dans la suite de l'article, nous verrons une des applications de la réflectivité, sur une surface très perturbée de platine déposé sur MgO et présentant une croissance en îlots. Nous verrons que la réflectivité permet d'estimer le taux de recouvrement de la surface, mais que des problèmes persistent dans la simulation de l'intégralité des données expérimentales. Les résultats obtenus en MET viendront compléter ceux issus de la réflectivité.

The influence of the hippocampus and declarative memory on word use: Patients with amnesia use less imageable words

PubMed Central

Hilverman, Caitlin; Cook, Susan Wagner; Duff, Melissa C.

2018-01-01

Hippocampal functioning contributes to our ability to generate multifaceted, imagistic event representations. Patients with hippocampal damage produce event narratives that contain fewer details and fewer imagistic features. We hypothesized that impoverished memory representations would influence language at the word level, yielding words lower in imageability and concreteness. We tested this by examining language produced by patients with bilateral hippocampal damage and severe declarative memory impairment, and brain-damaged and healthy comparison groups. Participants described events from the real past, imagined past, imagined present, and imagined future. We analyzed the imageability and concreteness of words used. Patients with amnesia used words that were less imageable than those of comparison groups across time periods, even when accounting for the amount of episodic detail in narratives. Moreover, all participants used words that were relatively more imageable when discussing real past events than other time periods. Taken together, these findings suggest that the memory that we have for an event affects how we talk about that event, and this extends all the way to the individual words that we use. PMID:28970108

Evaluation of the Navys Sea/Shore Flow Policy

DTIC Science & Technology

2016-06-01

CNA developed an independent Discrete -Event Simulation model to evaluate and assess the effect of alternative sea/shore flow policies. In this study...remains, even if the system is optimized. In building a Discrete -Event Simulation model, we discovered key factors that should be included in the... Discrete -Event Simulation model to evaluate the impact of sea/shore flow policy (the DES-SSF model) and compared the results with the SSFM for one

75 FR 60133 - Agency Information Collection Activities: Declaration of Ultimate Consignee That Articles Were...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-29

... Activities: Declaration of Ultimate Consignee That Articles Were Exported for Temporary Scientific or... the Declaration of Ultimate Consignee That Articles Were Exported for Temporary Scientific or...: Title: Declaration of Ultimate Consignee That Articles Were Exported for Temporary Scientific or...

76 FR 11254 - Agency Information Collection Activities: Declaration of Unaccompanied Articles

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-01

... Activities: Declaration of Unaccompanied Articles AGENCY: U.S. Customs and Border Protection (CBP... collection requirement concerning the Declaration of Unaccompanied Articles (CBP Form 255). This request for...: Title: Declaration of Unaccompanied Articles. OMB Number: 1651-0030. Form Number: CBP Form 255. Abstract...

44 CFR 204.21 - Fire management assistance declaration criteria.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Declaration Process § 204.21 Fire management assistance declaration criteria. (a) Determinations. We will... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Fire management assistance declaration criteria. 204.21 Section 204.21 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT...

44 CFR 204.21 - Fire management assistance declaration criteria.

Code of Federal Regulations, 2014 CFR

2014-10-01

... Declaration Process § 204.21 Fire management assistance declaration criteria. (a) Determinations. We will... 44 Emergency Management and Assistance 1 2014-10-01 2014-10-01 false Fire management assistance declaration criteria. 204.21 Section 204.21 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT...

44 CFR 204.21 - Fire management assistance declaration criteria.

Code of Federal Regulations, 2011 CFR

2011-10-01

... Declaration Process § 204.21 Fire management assistance declaration criteria. (a) Determinations. We will... 44 Emergency Management and Assistance 1 2011-10-01 2011-10-01 false Fire management assistance declaration criteria. 204.21 Section 204.21 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT...

44 CFR 204.21 - Fire management assistance declaration criteria.

Code of Federal Regulations, 2012 CFR

2012-10-01

... Declaration Process § 204.21 Fire management assistance declaration criteria. (a) Determinations. We will... 44 Emergency Management and Assistance 1 2012-10-01 2011-10-01 true Fire management assistance declaration criteria. 204.21 Section 204.21 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT...

44 CFR 204.21 - Fire management assistance declaration criteria.

Code of Federal Regulations, 2013 CFR

2013-10-01

... Declaration Process § 204.21 Fire management assistance declaration criteria. (a) Determinations. We will... 44 Emergency Management and Assistance 1 2013-10-01 2013-10-01 false Fire management assistance declaration criteria. 204.21 Section 204.21 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT...

75 FR 65696 - Ohio Disaster #OH-00025 Declaration of Economic Injury

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-26

... Counties: Auglaize, Mercer. Contiguous Counties: Ohio: Allen, Darke, Hardin, Logan, Shelby, Van Wert... SMALL BUSINESS ADMINISTRATION [Disaster Declaration 12359] Ohio Disaster OH-00025 Declaration of... Economic Injury Disaster Loan (EIDL) declaration for the State of Ohio, dated 10/19/2010. Incident: Toxic...

Developmental dissociation between the maturation of procedural memory and declarative memory.

PubMed

Finn, Amy S; Kalra, Priya B; Goetz, Calvin; Leonard, Julia A; Sheridan, Margaret A; Gabrieli, John D E

2016-02-01

Declarative memory and procedural memory are known to be two fundamentally different kinds of memory that are dissociable in their psychological characteristics and measurement (explicit vs. implicit) and in the neural systems that subserve each kind of memory. Declarative memory abilities are known to improve from childhood through young adulthood, but the developmental maturation of procedural memory is largely unknown. We compared 10-year-old children and young adults on measures of declarative memory and working memory capacity and on four measures of procedural memory that have been strongly dissociated from declarative memory (mirror tracing, rotary pursuit, probabilistic classification, and artificial grammar). Children had lesser declarative memory ability and lesser working memory capacity than adults, but children exhibited learning equivalent to adults on all four measures of procedural memory. Therefore, declarative memory and procedural memory are developmentally dissociable, with procedural memory being adult-like by age 10years and declarative memory continuing to mature into young adulthood. Copyright © 2015 Elsevier Inc. All rights reserved.

Expert Opinion: Optimising Stent Deployment in Contemporary Practice: The Role of Intracoronary Imaging and Non-compliant Balloons.

PubMed

Seth, Ashok; Gupta, Sajal; Pratap Singh, Vivudh; Kumar, Vijay

2017-09-01

Final stent dimensions remain an important predictor of restenosis, target vessel revascularisation (TVR) and subacute stent thrombosis (ST), even in the drug-eluting stent (DES) era. Stent balloons are usually semi-compliant and thus even high-pressure inflation may not achieve uniform or optimal stent expansion. Post-dilatation with non-compliant (NC) balloons after stent deployment has been shown to enhance stent expansion and could reduce TVR and ST. Based on supporting evidence and in the absence of large prospective randomised outcome-based trials, post-dilatation with an NC balloon to achieve optimal stent expansion and maximal luminal area is a logical technical recommendation, particularly in complex lesion subsets.

Revising psychoanalytic interpretations of the past. An examination of declarative and non-declarative memory processes.

PubMed

Davis, J T

2001-06-01

The author reviews a contemporary cognitive psychology perspective on memory that views memory as being composed of multiple separate systems. Most researchers draw a fundamental distinction between declarative/explicit and non-declarative/implicit forms of memory. Declarative memory is responsible for the conscious recollection of facts and events--what is typically meant by the everyday and the common psychoanalytic use of the word 'memory'. Non-declarative forms of memory, in contrast, are specialised processes that influence experience and behaviour without representing the past in terms of any consciously accessible content. They operate outside of an individual's awareness, but are not repressed or otherwise dynamically unconscious. Using this theoretical framework, the question of how childhood relationship experiences are carried forward from the past to influence the present is examined. It is argued that incorporating a conceptualisation of non-declarative memory processing into psychoanalytic theory is essential. Non-declarative memory processes are capable of forming complex and sophisticated representations of the interpersonal world. These non-declarative memory processes exert a major impact on interpersonal experience and behaviour that needs to be analysed on its own terms and not mistakenly viewed as a form of resistance.

78 FR 73581 - Massachusetts Disaster #MA-00057 Declaration of Economic Injury

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-06

... Declaration of Economic Injury AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This is a notice of an Economic Injury Disaster Loan (EIDL) declaration for the Commonwealth of Massachusetts... given that as a result of the Administrator's EIDL declaration, applications for economic injury...

17 CFR 250.22 - Applications and declarations.

Code of Federal Regulations, 2010 CFR

2010-04-01

... § 250.22 Applications and declarations. (a) Joinder. As far as practicable combined or joint applications or declarations shall be filed with respect to the same or related transactions or where related... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Applications and declarations...

49 CFR 374.405 - Baggage excess value declaration procedures.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 5 2010-10-01 2010-10-01 false Baggage excess value declaration procedures. 374... REGULATIONS PASSENGER CARRIER REGULATIONS Notice of and Procedures for Baggage Excess Value Declaration § 374.405 Baggage excess value declaration procedures. All motor common carriers of passengers and baggage...

77 FR 58901 - California Disaster #CA-00192; Declaration of Economic Injury

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-24

... SMALL BUSINESS ADMINISTRATION [Disaster Declaration 13290] California Disaster CA-00192; Declaration of Economic Injury AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This is a notice of an Economic Injury Disaster Loan (EIDL) declaration for the State of California, dated 09/14...

77 FR 58901 - California Disaster #CA-00193; Declaration of Economic Injury

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-24

... SMALL BUSINESS ADMINISTRATION [Disaster Declaration 13291] California Disaster CA-00193; Declaration of Economic Injury AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This is a notice of an Economic Injury Disaster Loan (EIDL) declaration for the State of California, dated 09/14...

78 FR 67209 - Florida Disaster #FL-00094 Declaration of Economic Injury

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-08

... SMALL BUSINESS ADMINISTRATION [Disaster Declaration 13804] Florida Disaster FL-00094 Declaration of Economic Injury AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This is a notice of an Economic Injury Disaster Loan (EIDL) declaration for the State of Florida, dated 10/31/2013...

78 FR 69101 - Agency Information Collection Activities: Declaration of the Ultimate Consignee That Articles...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-18

... Activities: Declaration of the Ultimate Consignee That Articles Were Exported for Temporary Scientific or... the Declaration of the Ultimate Consignee that Articles were Exported for Temporary Scientific or...: Title: Declaration of the Ultimate Consignee that Articles were Exported for Temporary Scientific or...

77 FR 76063 - Agency Information Collection Activities: Declaration for Free Entry of Unaccompanied Articles

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-26

... Activities: Declaration for Free Entry of Unaccompanied Articles AGENCY: U.S. Customs and Border Protection... collection requirement concerning the Declaration for Free Entry of Unaccompanied Articles (Form 3299). This... concerning the following information collection: Title: Declaration for Free Entry of Unaccompanied Articles...

78 FR 40819 - Washington Disaster # WA-00038 Declaration of Economic Injury

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-08

... Declaration of Economic Injury AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This is a notice of an Economic Injury Disaster Loan (EIDL) declaration for the State of Washington, dated 06/27... given that as a result of the Administrator's EIDL declaration, applications for economic injury...

78 FR 61442 - California Disaster #CA-00213 Declaration of Economic Injury

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-03

... Declaration of Economic Injury AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This is a notice of an Economic Injury Disaster Loan (EIDL) declaration for the State of California, dated 09/26... given that as a result of the Administrator's EIDL declaration, applications for economic injury...

44 CFR 204.26 - Appeal of fire management assistance declaration denial.

Code of Federal Regulations, 2011 CFR

2011-10-01

... PROGRAM Declaration Process § 204.26 Appeal of fire management assistance declaration denial. (a... 44 Emergency Management and Assistance 1 2011-10-01 2011-10-01 false Appeal of fire management assistance declaration denial. 204.26 Section 204.26 Emergency Management and Assistance FEDERAL EMERGENCY...

44 CFR 204.26 - Appeal of fire management assistance declaration denial.

Code of Federal Regulations, 2014 CFR

2014-10-01

... PROGRAM Declaration Process § 204.26 Appeal of fire management assistance declaration denial. (a... 44 Emergency Management and Assistance 1 2014-10-01 2014-10-01 false Appeal of fire management assistance declaration denial. 204.26 Section 204.26 Emergency Management and Assistance FEDERAL EMERGENCY...

44 CFR 204.26 - Appeal of fire management assistance declaration denial.

Code of Federal Regulations, 2010 CFR

2010-10-01

... PROGRAM Declaration Process § 204.26 Appeal of fire management assistance declaration denial. (a... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Appeal of fire management assistance declaration denial. 204.26 Section 204.26 Emergency Management and Assistance FEDERAL EMERGENCY...

44 CFR 204.26 - Appeal of fire management assistance declaration denial.

Code of Federal Regulations, 2012 CFR

2012-10-01

... PROGRAM Declaration Process § 204.26 Appeal of fire management assistance declaration denial. (a... 44 Emergency Management and Assistance 1 2012-10-01 2011-10-01 true Appeal of fire management assistance declaration denial. 204.26 Section 204.26 Emergency Management and Assistance FEDERAL EMERGENCY...

44 CFR 204.26 - Appeal of fire management assistance declaration denial.

Code of Federal Regulations, 2013 CFR

2013-10-01

... PROGRAM Declaration Process § 204.26 Appeal of fire management assistance declaration denial. (a... 44 Emergency Management and Assistance 1 2013-10-01 2013-10-01 false Appeal of fire management assistance declaration denial. 204.26 Section 204.26 Emergency Management and Assistance FEDERAL EMERGENCY...

39 CFR 946.11 - Disposition of property declared abandoned.

Code of Federal Regulations, 2010 CFR

2010-07-01

... DISPOSITION OF STOLEN MAIL MATTER AND PROPERTY ACQUIRED BY THE POSTAL INSPECTION SERVICE FOR USE AS EVIDENCE § 946.11 Disposition of property declared abandoned. Property declared abandoned, including cash, and... 39 Postal Service 1 2010-07-01 2010-07-01 false Disposition of property declared abandoned. 946.11...

39 CFR 946.11 - Disposition of property declared abandoned.

Code of Federal Regulations, 2011 CFR

2011-07-01

... DISPOSITION OF STOLEN MAIL MATTER AND PROPERTY ACQUIRED BY THE POSTAL INSPECTION SERVICE FOR USE AS EVIDENCE § 946.11 Disposition of property declared abandoned. Property declared abandoned, including cash, and... 39 Postal Service 1 2011-07-01 2011-07-01 false Disposition of property declared abandoned. 946.11...

75 FR 54661 - Alaska Disaster #AK-00018 Declaration of Economic Injury

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-08

... SMALL BUSINESS ADMINISTRATION [Disaster Declaration 12292] Alaska Disaster AK-00018 Declaration of Economic Injury AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This is a notice of an Economic Injury Disaster Loan (EIDL) declaration for the State of Alaska, dated 08/27/2010. Incident...

77 FR 71667 - Alaska Disaster #AK-00026 Declaration of Economic Injury

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-03

... SMALL BUSINESS ADMINISTRATION [Disaster Declaration 13393] Alaska Disaster AK-00026 Declaration of Economic Injury AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This is a notice of an Economic Injury Disaster Loan (EIDL) declaration for the State of Alaska, dated 11/21/2012. Incident: 2012...

A Comparison of Declarative and Hybrid Declarative-Procedural Models for Rover Operations

NASA Technical Reports Server (NTRS)

Knight, Russell; Rabideau, Gregg; Lenda, Matthew; Maldague, Pierre

2012-01-01

The MAPGEN [2] (Mixed-initiative Activity Plan GENerator) planning system is a great example of a hybrid procedural/declarative system where the advantages of each are leveraged to produce an effective planner/scheduler for Mars Exploration Rover tactical planning. We explore the adaptation of the same domain to an entirely declarative planning system (ASPEN [4] Activity Scheduling and Planning ENvironment), and demonstrate that, with some translation, much of the procedural knowledge encoding is amenable to a declarative knowledge encoding.

Evaluation of Accessory Lacrimal Gland in Muller's Muscle Conjunctival Resection Specimens for Precursor Cell Markers and Biological Markers of Dry Eye Disease.

PubMed

Ali, Marwan; Shah, Dhara; Pasha, Zeeshan; Jassim, Sarmad H; Jassim Jaboori, Assraa; Setabutr, Pete; Aakalu, Vinay K

2017-04-01

The accessory lacrimal glands (ALGs) are an understudied component of the tear functional unit, even though they are important in the development of dry eye syndrome (DES). To advance our understanding of aging changes, regenerative potential, and histologic correlates to human characteristics, we investigated human ALG tissue from surgical samples to determine the presence or absence of progenitor cell markers and lacrimal epithelial markers and to correlate marker expression to relevant patient characteristics. ALG tissues obtained from Muller's muscle conjunctival resection (MMCR) specimens were created using tissue microarrays (TMAs). Immunofluorescence staining of MMCR sections was performed using primary antibodies specific to cell protein markers. Cell marker localization in TMAs was then assessed by two blinded observers using a standardized scoring system. Patient characteristics including age, race, and status of ocular surface health were then compared against expression of stem cell markers. Human ALG expressed a number of epithelial markers, and in particular, histatin-1 was well correlated with the expression of epithelial markers and was present in most acini. In addition, we noted the presence of precursor cell markers nestin, ABCG2, and CD90 in ALG tissue. There was a decrease in precursor cell marker expression with increasing age. Finally, we noted that a negative association was present between histatin-1 expression and DES. Thus, we report for the first time that human ALG tissues contain precursor marker-positive cells and that this marker expression may decrease with increasing age. Moreover, histatin-1 expression may be decreased in DES. Future studies will be performed to use these cell markers to isolate and culture lacrimal epithelial cells from heterogeneous tissues, determine the relevance of histatin-1 expression to DES, and isolate candidate precursor cells from ALG tissue.

Combining optical remote sensing, agricultural statistics and field observations for culture recognition over a peri-urban region

NASA Astrophysics Data System (ADS)

Delbart, Nicolas; Emmanuelle, Vaudour; Fabienne, Maignan; Catherine, Ottlé; Jean-Marc, Gilliot

2017-04-01

This study explores the potential of multi-temporal optical remote sensing, with high revisit frequency, to derive missing information on agricultural calendar and crop types over the agricultural lands in the Versailles plain in the western Paris suburbs. This study comes besides past and ongoing studies on the use of radar and high spatial resolution optical remote sensing to monitor agricultural practices in this study area (e.g. Vaudour et al. 2014). Agricultural statistics, such as the Land Parcel Identification System (LPIS) for France, permit to know the nature of annual crops for each digitized declared field of this land parcel registry. However, within each declared field several cropped plots and a diversity of practices may exist, being marked by agricultural rotations which vary both spatially and temporally within it and differ from one year to the other. Even though the new LPIS to be released in 2016 is expected to describe individual plots within declared fields, its attributes may not enable to discriminate between winter and spring crops. Here we evaluate the potential of high observation frequency remote sensing to differentiate seasonal crops based essentially on the seasonality of the spectral properties. In particular, we use the Landsat data to spatially disaggregate the LPIS statistical data, on the basis of the analysis of the remote sensing spectral seasonality measured on a number of selected ground-observed fields. This work is carried out in the framework of the CNES TOSCA-PLEIADES-CO of the French Space Agency.

19 CFR 4.75 - Incomplete manifest; incomplete export declarations; bond.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 1302-A (see § 4.63) in accordance with 46 U.S.C. 91, or all required shipper's export declarations (see... declarations; bond. 4.75 Section 4.75 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND... export declarations have been filed with the port director: Albania Bulgaria Cambodia China, People's...

19 CFR 4.75 - Incomplete manifest; incomplete export declarations; bond.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 1302-A (see § 4.63) in accordance with 46 U.S.C. 91, or all required shipper's export declarations (see... declarations; bond. 4.75 Section 4.75 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND... export declarations have been filed with the port director: Albania Bulgaria Cambodia China, People's...

19 CFR 4.75 - Incomplete manifest; incomplete export declarations; bond.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 1302-A (see § 4.63) in accordance with 46 U.S.C. 91, or all required shipper's export declarations (see... declarations; bond. 4.75 Section 4.75 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND... export declarations have been filed with the port director: Albania Bulgaria Cambodia China, People's...

19 CFR 4.75 - Incomplete manifest; incomplete export declarations; bond.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 1302-A (see § 4.63) in accordance with 46 U.S.C. 91, or all required shipper's export declarations (see... declarations; bond. 4.75 Section 4.75 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND... export declarations have been filed with the port director: Albania Bulgaria Cambodia China, People's...

15 CFR 712.3 - Initial declaration requirements for declared facilities which are engaged in the production of...

Code of Federal Regulations, 2010 CFR

2010-01-01

... Foreign Trade (Continued) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE CHEMICAL WEAPONS CONVENTION REGULATIONS ACTIVITIES INVOLVING SCHEDULE 1 CHEMICALS § 712.3 Initial declaration requirements for... declared facilities which are engaged in the production of Schedule 1 chemicals for purposes not prohibited...

21 CFR 1313.23 - Distribution of export declaration.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 9 2010-04-01 2010-04-01 false Distribution of export declaration. 1313.23... EXPORTATION OF LIST I AND LIST II CHEMICALS Exportation of Listed Chemicals § 1313.23 Distribution of export declaration. The required three copies of the listed chemical export declaration (DEA Form 486) will be...

Event-Related Potential Correlates of Declarative and Non-Declarative Sequence Knowledge

ERIC Educational Resources Information Center

Ferdinand, Nicola K.; Runger, Dennis; Frensch, Peter A.; Mecklinger, Axel

2010-01-01

The goal of the present study was to demonstrate that declarative and non-declarative knowledge acquired in an incidental sequence learning task contributes differentially to memory retrieval and leads to dissociable ERP signatures in a recognition memory task. For this purpose, participants performed a sequence learning task and were classified…

19 CFR 145.11 - Declarations of value and invoices.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 19 Customs Duties 2 2010-04-01 2010-04-01 false Declarations of value and invoices. 145.11 Section... value and invoices. (a) Customs declaration. A clear and complete Customs declaration on the form provided by the foreign post office, giving a full and accurate description of the contents and value of...

15 CFR 712.3 - Initial declaration requirements for declared facilities which are engaged in the production of...

Code of Federal Regulations, 2011 CFR

2011-01-01

... Foreign Trade (Continued) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE CHEMICAL WEAPONS CONVENTION REGULATIONS ACTIVITIES INVOLVING SCHEDULE 1 CHEMICALS § 712.3 Initial declaration requirements for... declared facilities which are engaged in the production of Schedule 1 chemicals for purposes not prohibited...

24 CFR 203.493 - Declaration of trust.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Declaration of trust. 203.493... Declaration of trust. A sale of a beneficial interest in a group of insured loans, where the interest to be... be made only pursuant to a declaration of trust, which has been approved by the Commissioner prior to...

24 CFR 203.434 - Declaration of trust.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Declaration of trust. 203.434... Mortgage § 203.434 Declaration of trust. A sale of a beneficial interest in a group of insured mortgages... interest in a specific mortgage shall be made only pursuant to a declaration of trust, which has been...

The revision of the Declaration of Helsinki: past, present and future.

PubMed

Carlson, Robert V; Boyd, Kenneth M; Webb, David J

2004-06-01

The World Medical Association's Declaration of Helsinki was first adopted in 1964. In its 40-year lifetime the Declaration has been revised five times and has risen to a position of prominence as a guiding statement of ethical principles for doctors involved in medical research. The most recent revision, however, has resulted in considerable controversy, particularly in the area of the ethical requirements surrounding placebo-controlled trials and the question of responsibilities to research participants at the end of a study. This review considers the past versions of the Declaration of Helsinki and asks the question: How exactly has the text of the Declaration changed throughout its lifetime? Regarding the present form of the Declaration of Helsinki we ask: What are the major changes in the most recent revision and what are the controversies surrounding them? Finally, building on the detailed review of the past and present versions of the Declaration of Helsinki, we give consideration to some of the possible future trajectories for the Declaration in the light of its history and standing in the world of the ethics of medical research.

A shared resource between declarative memory and motor memory.

PubMed

Keisler, Aysha; Shadmehr, Reza

2010-11-03

The neural systems that support motor adaptation in humans are thought to be distinct from those that support the declarative system. Yet, during motor adaptation changes in motor commands are supported by a fast adaptive process that has important properties (rapid learning, fast decay) that are usually associated with the declarative system. The fast process can be contrasted to a slow adaptive process that also supports motor memory, but learns gradually and shows resistance to forgetting. Here we show that after people stop performing a motor task, the fast motor memory can be disrupted by a task that engages declarative memory, but the slow motor memory is immune from this interference. Furthermore, we find that the fast/declarative component plays a major role in the consolidation of the slow motor memory. Because of the competitive nature of declarative and nondeclarative memory during consolidation, impairment of the fast/declarative component leads to improvements in the slow/nondeclarative component. Therefore, the fast process that supports formation of motor memory is not only neurally distinct from the slow process, but it shares critical resources with the declarative memory system.

Disaster declarations associated with bushfires, floods and storms in New South Wales, Australia between 2004 and 2014

PubMed Central

Sewell, T.; Stephens, R. E.; Dominey-Howes, D.; Bruce, E.; Perkins-Kirkpatrick, S.

2016-01-01

Australia regularly experiences disasters triggered by natural hazards and New South Wales (NSW) the most populous State is no exception. To date, no publically available spatial and temporal analyses of disaster declarations triggered by hazards (specifically, bushfires, floods and storms) in NSW have been undertaken and no studies have explored the relationship between disaster occurrence and socio-economic disadvantage. We source, collate and analyse data about bushfire, flood and storm disaster declarations between 2004 and 2014. Floods resulted in the most frequent type of disaster declaration. The greatest number of disaster declarations occurred in 2012–2013. Whilst no significant Spearman’s correlation exists between bushfire, flood and storm disaster declarations and the strength of the El Niño/Southern Oscillation (ENSO) phase, we observe that bushfire disaster declarations were much more common during El Niño, and flood disaster declarations were five times more common during La Niña phases. We identify a spatial cluster or ‘hot spot’ of disaster declarations in the northeast of the State that is also spatially coincident with 43% of the most socio-economically disadvantaged Local Government Areas in NSW. The results have implications for disaster risk management in the State. PMID:27819298

Propagation d'impulsions femtosecondes térawatts dans l'atmosphère et applications

NASA Astrophysics Data System (ADS)

Méjean, G.

2005-11-01

Propagation of femtosecond terawatt laser in atmosphere and applications When ultrasshort and high-power laser pulses propagate across the atmosphere, self-guided filaments of 100 μm radius are formed. They result from a balance between Kerr self-focusing and defocusing by the plasma generated by multiphoton ionisation. During this work, we showed that the white light spectrum generated in filament spans from the infrared (4.5 μm) to the ultraviolet (230 nm) thanks to Third Harmonic Generation and self-phase modulation. We charaterized the propagation under different conditions (rain, smog, turbulence) to developp different atmospheric applications. In particular, we demostrated multi-parameters LIDAR for relative humidity as well as atmospheric pollution remote sensing. Furthermore, it is possible to detect and to identify biological aerosols or solid targets (LIBS) at remote distances, by non-linear processes induced in situ by the high intensity delivered by filaments. Moreover, we demonstrated that guiding and triggering high-voltage discharge thanks to a femsecond high-powered pulse is possible even under a rain with an efficiency comparable to that observed in dry air. We also impoved the efficiency of a two pulses configurations (a femtosecond pulse and a subsequent nanosecond pulse). These results raise hope that lightning could be triggered and guided by laser pulses in the future. Les impulsions laser ultra-brèves (fs) et ultra-intenses (TW) forment, au cours de leur propagation non-linéaire dans l'atmosphère, des structures auto-guidées, d'une centaine de microns de diamètre, appelées filaments. Ces filaments résultent d'un équilibre dynamique entre l'effet Kerr qui focalise le faisceau et la défocalisation due au plasma généré au sein de ceux-ci. Au cours des différentes études rapportées ici, nous avons mesuré que le spectre de lumière blanche issue de l'automodulation de phase et de la génération de troisième harmonique s'étend de l'ultraviolet (230 nm) à l'infrarouge (4,5 μm). De même, la propagation dans l'air, sous différentes conditions (pluie, brouillard, turbulence), des faisceaux térawatts femtosecondes a été caractérisée afin de développer des applications atmosphériques. Il nous a ainsi été possible de développer le LIDAR à lumière blanche pour réaliser des mesures préliminaires d'ozone et d'aérosols simultanément. De même, grâce à la propagation fortement non-linéaire du faisceau qui permet de transporter des hautes intensités sur de longue distance, nous avons pu détecter et identifier, à distance, des aérosols biologiques et des cibles solides (LIBS) en induisant in situ des effets non-linéaires. Enfin, nous avons montré que le déclenchement et le guidage de décharges de haute tension par une impulsion laser femtoseconde sous la pluie reste possible avec une efficacité comparable à l'atmosphère sèche. D'autre part, une configuration à double impulsion laser augmente l'efficacité de déclenchement des décharges. Ces résultats nous rapproche de la perspective de déclenchement et guidage de foudre par laser.

Open-Source Python Tools for Deploying Interactive GIS Dashboards for a Billion Datapoints on a Laptop

NASA Astrophysics Data System (ADS)

Steinberg, P. D.; Bednar, J. A.; Rudiger, P.; Stevens, J. L. R.; Ball, C. E.; Christensen, S. D.; Pothina, D.

2017-12-01

The rich variety of software libraries available in the Python scientific ecosystem provides a flexible and powerful alternative to traditional integrated GIS (geographic information system) programs. Each such library focuses on doing a certain set of general-purpose tasks well, and Python makes it relatively simple to glue the libraries together to solve a wide range of complex, open-ended problems in Earth science. However, choosing an appropriate set of libraries can be challenging, and it is difficult to predict how much "glue code" will be needed for any particular combination of libraries and tasks. Here we present a set of libraries that have been designed to work well together to build interactive analyses and visualizations of large geographic datasets, in standard web browsers. The resulting workflows run on ordinary laptops even for billions of data points, and easily scale up to larger compute clusters when available. The declarative top-level interface used in these libraries means that even complex, fully interactive applications can be built and deployed as web services using only a few dozen lines of code, making it simple to create and share custom interactive applications even for datasets too large for most traditional GIS systems. The libraries we will cover include GeoViews (HoloViews extended for geographic applications) for declaring visualizable/plottable objects, Bokeh for building visual web applications from GeoViews objects, Datashader for rendering arbitrarily large datasets faithfully as fixed-size images, Param for specifying user-modifiable parameters that model your domain, Xarray for computing with n-dimensional array data, Dask for flexibly dispatching computational tasks across processors, and Numba for compiling array-based Python code down to fast machine code. We will show how to use the resulting workflow with static datasets and with simulators such as GSSHA or AdH, allowing you to deploy flexible, high-performance web-based dashboards for your GIS data or simulations without needing major investments in code development or maintenance.

A Unified Algebraic and Logic-Based Framework Towards Safe Routing Implementations

DTIC Science & Technology

2015-08-13

Software - defined Networks ( SDN ). We developed a declarative platform for implementing SDN protocols using declarative...and debugging several SDN applications. Example-based SDN synthesis. Recent emergence of software - defined networks offers an opportunity to design...domain of Software - defined Networks ( SDN ). We developed a declarative platform for implementing SDN protocols using declarative networking

Investigating the Contribution of Procedural and Declarative Memory to the Acquisition of Past Tense Morphology: Evidence from Finnish

ERIC Educational Resources Information Center

Kidd, Evan; Kirjavainen, Minna

2011-01-01

The present paper reports on a study that investigated the role of procedural and declarative memory in the acquisition of Finnish past tense morphology. Two competing models were tested. Ullman's (2004) declarative/procedural model predicts that procedural memory supports the acquisition of regular morphology, whereas declarative memory supports…

77 FR 32022 - Direct Final Negative Declaration and Withdrawal of Large Municipal Waste Combustors State Plan...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-31

... Negative Declaration and Withdrawal of Large Municipal Waste Combustors State Plan for Designated.... SUMMARY: EPA is taking direct final action to approve Illinois' negative declaration and request for EPA..., the state may submit a letter of certification to that effect, or a negative declaration, in lieu of a...

15 CFR 711.8 - How to request authorization from BIS to make electronic submissions of declarations or reports.

Code of Federal Regulations, 2011 CFR

2011-01-01

... to make electronic submissions of declarations or reports. 711.8 Section 711.8 Commerce and Foreign..., REPORTING, AND ADVANCE NOTIFICATION REQUIREMENTS, AND THE ELECTRONIC FILING OF DECLARATIONS AND REPORTS § 711.8 How to request authorization from BIS to make electronic submissions of declarations or reports...

15 CFR 711.8 - How to request authorization from BIS to make electronic submissions of declarations or reports.

Code of Federal Regulations, 2012 CFR

2012-01-01

... to make electronic submissions of declarations or reports. 711.8 Section 711.8 Commerce and Foreign..., REPORTING, AND ADVANCE NOTIFICATION REQUIREMENTS, AND THE ELECTRONIC FILING OF DECLARATIONS AND REPORTS § 711.8 How to request authorization from BIS to make electronic submissions of declarations or reports...

15 CFR 711.8 - How to request authorization from BIS to make electronic submissions of declarations or reports.

Code of Federal Regulations, 2013 CFR

2013-01-01

... to make electronic submissions of declarations or reports. 711.8 Section 711.8 Commerce and Foreign..., REPORTING, AND ADVANCE NOTIFICATION REQUIREMENTS, AND THE ELECTRONIC FILING OF DECLARATIONS AND REPORTS § 711.8 How to request authorization from BIS to make electronic submissions of declarations or reports...

15 CFR 711.8 - How to request authorization from BIS to make electronic submissions of declarations or reports.

Code of Federal Regulations, 2014 CFR

2014-01-01

... to make electronic submissions of declarations or reports. 711.8 Section 711.8 Commerce and Foreign..., REPORTING, AND ADVANCE NOTIFICATION REQUIREMENTS, AND THE ELECTRONIC FILING OF DECLARATIONS AND REPORTS § 711.8 How to request authorization from BIS to make electronic submissions of declarations or reports...

19 CFR 4.7 - Inward foreign manifest; production on demand; contents and form; advance filing of cargo...

Code of Federal Regulations, 2011 CFR

2011-04-01

...; contents and form; advance filing of cargo declaration. 4.7 Section 4.7 Customs Duties U.S. CUSTOMS AND... and form; advance filing of cargo declaration. (a) The master of every vessel arriving in the United..., and the following documents: (1) Cargo Declaration, Customs Form 1302, (2) Ship's Stores Declaration...

19 CFR 4.7 - Inward foreign manifest; production on demand; contents and form; advance filing of cargo...

Code of Federal Regulations, 2010 CFR

2010-04-01

...; contents and form; advance filing of cargo declaration. 4.7 Section 4.7 Customs Duties U.S. CUSTOMS AND... and form; advance filing of cargo declaration. (a) The master of every vessel arriving in the United..., and the following documents: (1) Cargo Declaration, Customs Form 1302, (2) Ship's Stores Declaration...

Teaching the Universal Declaration of Human Rights in a U.S. Government Course.

ERIC Educational Resources Information Center

Rosen, Philip

1990-01-01

Discusses the United Nations Universal Declaration of Human Rights as a vehicle for learning democratic and humanistic values. Provides goals for instruction about the Declaration. Compares the Declaration to U.S. Supreme Court cases and congressional acts, and suggests classroom activities using it. Includes an appendix on Supreme Court cases and…

26 CFR 1.6016-2 - Contents of declaration of estimated tax.

Code of Federal Regulations, 2010 CFR

2010-04-01

... income tax after the exemption and the credits, if any, should be filed as a tentative declaration within... 26 Internal Revenue 13 2010-04-01 2010-04-01 false Contents of declaration of estimated tax. 1... (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES Tax Returns Or Statements § 1.6016-2 Contents of declaration...

A World Worth Living in ICAE 8th World Assembly Declaration (June 2011)

ERIC Educational Resources Information Center

Adult Learning, 2012

2012-01-01

This article presents the International Council of Adult Education (ICAE) 8th World Assembly Declaration (June 2011). This declaration focuses on adult educators' conviction in the possibility of a "world worth living in," and their declaration of their collective determination to work towards making it a reality all around the planet.

Declarations on euthanasia and assisted dying.

PubMed

Inbadas, Hamilton; Zaman, Shahaduz; Whitelaw, Sandy; Clark, David

2017-10-01

Declarations on end-of-life issues are advocacy interventions that seek to influence policy, raise awareness and call others to action. Despite increasing prominence, they have attracted little attention from researchers. This study tracks the emergence, content, and purpose of declarations concerned with assisted dying and euthanasia, in the global context. The authors identified 62 assisted dying/euthanasia declarations covering 1974-2016 and analyzed them for originating organization, geographic scope, format, and stated viewpoint on assisted dying/euthanasia. The declarations emerged from diverse organizational settings and became more frequent over time. Most opposed assisted dying/euthanasia.

Declaring Conflict of Interest - Current State of Affairs in the Ophthalmic Literature.

PubMed

Schaefer, Jamie Lea; Aubert Bonn, Noemie; Craenen, Geert

2017-01-01

The importance of transparency with financial ties in biomedical research is widely recognized, and most peer-reviewed journals require declarations of Conflicts of Interest (COI). Nonetheless, variability in the consistency of declarations of COI has been sparsely assessed. To assess consistency and rates of COI declarations in the ophthalmic literature and the effectiveness of journal COI policies. We analyzed consistency and completeness of declaration of COI in the ophthalmic literature and compared the levels of completeness to specific journal requirements. Six-hundred forty-two peer reviewed articles satisfied the inclusion criteria. In 64%, COIs were unreported, in 25% declaration of COI was incomplete, and 11% of the articles reviewed had complete declaration of COI. Of the 33 journals in which the most frequently published authors' articles appeared, 10 required the authors to complete the International Committee of Medical Journal Editors (ICMJE) form or an equivalent form, but this did not affect the rates of COI declaration. In a random sampling of the most frequently published authors in the field of ophthalmology, declaration of COI was low and highly inconsistent. Requiring a standardized COI form has no significant effect on the rate of accurate COI reporting. Our findings lend support to the growing body of literature that shows that journals and editors may need to take a more active role in ensuring accurate and consistent COI reporting.

Policies and practices on competing interests of academic staff in Australian universities.

PubMed

Chapman, Simon; Morrell, Bronwen; Forsyth, Rowena; Kerridge, Ian; Stewart, Cameron

2012-04-16

To document the existence and provisions of Australian universities' policies on the competing interests of academic staff and university practices in recording, updating and making these declarations publicly accessible. A 14-item survey was sent to the vice-chancellors of 39 Australian universities and university websites were searched for relevant policies. Twelve universities declined to provide any information. Of the 27 that did, all had policies on staff competing interests. Fifteen did not require regular declarations from staff and only four required annual declarations. Eight universities maintained a centralised register of COIs of all staff and six had a mechanism in place that allowed members of the public to access information on COIs. None reported that they required that staff place their COI declarations on their website profiles and none had policies that indicated that staff should declare COIs when making a public comment. Australian universities vary significantly in their approaches to the declaration and management of competing interests. While two-thirds of Australian universities require staff to declare competing interests, this information is mostly inaccessible to the public. Australian universities should adopt a standard approach to the declaration and management of competing interests and commit to meaningful transparency and public accountability. This could include frequently updated declarations on website profiles of all staff. In addition, dialogue about what is needed to effectively deal with competing interests should be encouraged.

Le role du phytoplancton de petite taille (<20 mum) dans les variations des proprietes optiques des eaux du Saint-Laurent

NASA Astrophysics Data System (ADS)

Mas, Sebastien

Les mesures satellitaires de couleur des oceans sont largement determinees par les proprietes optiques inherentes (IOPs) des eaux de surface. D'autre part, le phytoplancton de petite taille (<20 mum) est le plus souvent dominant dans les oceans, et peut donc etre une source importante de variation des IOPs dans les oceans. Dans ce contexte, le but principal de ce doctorat etait de definir l'impact du phytoplancton (<20 mum) sur les variations des proprietes optiques de l'Estuaire et du Golfe du Saint-Laurent (Canada). Afin d'atteindre cet objectif, il etait necessaire de determiner en milieu controle les facteurs de variabilite des proprietes optiques cellulaires et des IOPs du phytoplancton (<20 mum) des eaux du Saint-Laurent, et d'evaluer la contribution du phytoplancton (<20 mum) aux proprietes optiques totales des eaux du Saint-Laurent. Des experiences en laboratoire ont montre que les variations des proprietes optiques des cellules phytoplanctoniques soumises a un cycle jour-nuit, ainsi qu'a des changements concomitants d'intensite lumineuse, peuvent contribuer significativement a la variabilite des proprietes optiques observee en milieu naturel. D'autres experiences ont, quant a elles, mis en evidence que les variations des proprietes optiques des cellules phytoplanctoniques dues aux phases de croissance peuvent alterer les IOPs des oceans, particulierement pendant les periodes de floraison. De plus, la presence de bacteries et de particules detritiques peut egalement affecter la variabilite des IOPs totales, notamment la diffusion. Au printemps, dans l'Estuaire et le Golfe du Saint-Laurent, la contribution du phytoplancton <20 mum aux IOPs presentait des differences regionales evidentes pour les proprietes d'absorption et de diffusion. En plus de la variabilite spatiale, les proprietes optiques cellulaires presentaient des variations journalieres, et ce particulierement pour le picophytoplancton. Enfin, la plupart des differences observees dans les proprietes biooptiques, particulierement l'absorption, etaient attribuables a la contribution du phytoplancton <20 mum. Ceci confirme l'importance de la structure de taille des communautes phytoplanctoniques dans les modeles bio-optiques appliques au Saint-Laurent. L'ensemble des resultats a permis de mettre en evidence l'importance des mecanismes de photoacclimatation et de synchronisation du cycle cellulaire du phytoplancton sur les variations journalieres des IOPs, ainsi que de l'etat physiologique relie au stade de croissance sur les variations temporelles a long terme des IOPs. De plus, le phytoplancton <20 mum contribue de maniere importante aux IOPs et a leur variabilite dans l'Estuaire et le Golfe du St-Laurent, et ce particulierement pour l'absorption. Cette etude de doctorat souligne donc l'importance du phytoplancton <20 mum sur la variabilite des IOPs des oceans.

Voyage dans le noir. Trous noirs, matière noire, énergie noire et antimatière [Journey in the dark. Black holes, dark matter, dark energy and antimatter

DOE Office of Scientific and Technical Information (OSTI.GOV)

Alvarez-Gaume, Luis; Doser, Michael; Grojean, Chri

2009-11-26

Et si nous faisions avec les physiciens un voyage dans le noir ? De l'astrophysique à la physique des particules les trois noirs, la matière noire, l'énergie noire ou l’antimatière intriguent et fascinent. Que sont ces objets qui bousculent nos idées et qui véhiculent parfois des craintes irraisonnées? Luis Alvarez-Gaume, Michael Doser et Christophe Grojean, physiciens du CERN vous invitent à mettre en lumière (!) les constituants de base de la matière et à explorer les mystères de la physique contemporaine. Une soirée lumineuse pour éclairer des concepts et ne plus avoir peur du noir. [ What if we mademore » a trip to the physicists in the dark? From astrophysics to particle physics the three blacks, dark matter, dark energy or antimatter intrigue and fascinate. What are these objects that jostle our ideas and sometimes convey irrational fears? Luis Alvarez-Gaume, Michael Doser and Christophe Grojean, CERN physicists invite you to highlight (!) The basic constituents of matter and to explore the mysteries of contemporary physics. A bright evening to illuminate concepts and not be afraid of the dark.]« less

Excitations Élémentaires au Voisinage de la Surface de Séparation d'un Métal Normal et d'un Métal Supraconducteur

NASA Astrophysics Data System (ADS)

Saint-James, Par D.

On étudie le spectre d'excitation pour une couche de métal normal déposée sur un supraconducteur. On montre que si l'interaction attractive électron-électron est négligeable dans le métal normal, il n'y a pas de gap d'énergie dans le spectre d'excitation, même si l'épaisseur de la couche normale est petite. Une étude analogue, conduisant à une conclusion similaire, est menée pour deux supraconducteurs accolés et pour des sphères de métal normal baignant dans un supraconducteur. L'effet prévu pourrait expliquer quelques résultats particuliers observés dans des mesures d'effet tunnel dans des supraconducteurs durs. The excitation spectrum of a layer of normal metal (N) deposited on a superconducting substrate (S) is discussed. It is shown that if the electron-electron attractive interaction is negligibly small in (N) there is no energy gap in the excitation spectrum even if the thickness of the layer (N) is small. A similar study, with equivalent conclusions, has been carried out for two superconductors and for normal metal spheres embedded in a superconductor. The effect may possibly explain some peculiar results of tunnelling experiments on hard superconductors.

Inverse Relationship between Serum VEGF Levels and Late In-Stent Restenosis of Drug-Eluting Stents

PubMed Central

Shen, Li; Ji, Meng; Cai, Sishi; Chen, Jiahui; Yao, Zhifeng

2017-01-01

Late in-stent restenosis (ISR) has raised concerns regarding the long-term efficacy of drug-eluting stents (DES). The role of vascular endothelial growth factor (VEGF) in the pathological process of ISR is controversial. This retrospective study aimed to investigate the relationship between serum VEGF levels and late ISR in patients with DES implantation. A total of 158 patients who underwent angiography follow-up beyond 1 year after intervention were included. The study population was classified into ISR and non-ISR groups. The ISR group was further divided according to follow-up duration and Mehran classification. VEGF levels were significantly lower in the ISR group than in the non-ISR group [96.34 (48.18, 174.14) versus 179.14 (93.59, 307.74) pg/mL, p < 0.0001]. Multivariate regression revealed that VEGF level, procedure age, and low-density lipoprotein cholesterol were independent risk factors for late ISR formation. Subgroup analysis demonstrated that VEGF levels were even lower in the very late (≥5 years) and diffuse ISR group (Mehran patterns II, III, and IV) than in the late ISR group (1–4 years) and the focal ISR group (Mehran pattern I), respectively. Furthermore, significant difference was found between diffuse and focal ISR groups. Serum VEGF levels were inversely associated with late ISR after DES implantation. PMID:28373989

[The decree of June 15th, 1888, the first text that legislates the pharmacy practice in Tunisia and the progress of the pharmaceutical legislation before and after the independence].

PubMed

Ben Azzouna, Rana; Hamdane, Ridha

2007-01-01

In 1881, the French protectorate is established in Tunisia whose independence will not be officially declared before March 20th, 1956. This article presents the content of the decree of June 15th, 1888, the first text that legislates pharmacy practice in Tunisia. The publication of this decree, a real fundamental text, did not put an end to the illegal practice of pharmacy in the Regency, which could be explained by the few shortcomings of the text, the legislator's inability to implement the law, the ignorance and the inadvertency of the diplomats, and also the "regime of the surrenders" (le régime des capitulations) which, by preventing the pharmaceutical inspection, gave free rein to all the offenders. This situation led in the course of time to the promulgation of a number of laws which progressively allowed a better organization of the pharmaceutical profession in the Regency. The progress made by the pharmaceutical legislation throughout the French protectorate continued after the independence of Tunisia as is attested by the law number 73-55 of August 3rd, 1973 which is still in use at present.

La planification préalable des soins pour les patients en pédiatrie

PubMed Central

2008-01-01

RÉSUMÉ Les progrès médicaux et technologiques ont permis d’ac-croître les taux de survie et d’améliorer la qualité de vie des nourrissons, des enfants et des adolescents ayant des maladies chroniques mettant la vie en danger. La planifi-cation préalable des soins inclut le processus relié aux discussions sur les traitements essentiels au maintien de la survie et la détermination des objectifs des soins de longue durée. Les dispensateurs de soins pédiatriques ont l’obligation éthique d’assimiler cet aspect des soins médicaux. Le présent document de principes vise à aider les dispensateurs de soins à discuter de la planification préalable des soins des patients pédiatriques dans diverses situations. La planification préalable des soins exige des communications efficaces afin de clarifier les objectifs des soins et de s’entendre sur les traitements pertinents ou non pour réaliser ces objectifs, y compris les mesures de réanimation et les mesures palliatives.

Declarations on euthanasia and assisted dying

PubMed Central

Inbadas, Hamilton; Zaman, Shahaduz; Whitelaw, Sandy; Clark, David

2017-01-01

ABSTRACT Declarations on end-of-life issues are advocacy interventions that seek to influence policy, raise awareness and call others to action. Despite increasing prominence, they have attracted little attention from researchers. This study tracks the emergence, content, and purpose of declarations concerned with assisted dying and euthanasia, in the global context. The authors identified 62 assisted dying/euthanasia declarations covering 1974–2016 and analyzed them for originating organization, geographic scope, format, and stated viewpoint on assisted dying/euthanasia. The declarations emerged from diverse organizational settings and became more frequent over time. Most opposed assisted dying/euthanasia. PMID:28398131

Biodegradable-polymer drug-eluting stents vs. bare metal stents vs. durable-polymer drug-eluting stents: a systematic review and Bayesian approach network meta-analysis.

PubMed

Kang, Si-Hyuck; Park, Kyung Woo; Kang, Do-Yoon; Lim, Woo-Hyun; Park, Kyung Taek; Han, Jung-Kyu; Kang, Hyun-Jae; Koo, Bon-Kwon; Oh, Byung-Hee; Park, Young-Bae; Kandzari, David E; Cohen, David J; Hwang, Seung-Sik; Kim, Hyo-Soo

2014-05-01

The aim of this study was to compare the safety and efficacy of biodegradable-polymer (BP) drug-eluting stents (DES), bare metal stents (BMS), and durable-polymer DES in patients undergoing coronary revascularization, we performed a systematic review and network meta-analysis using a Bayesian framework. Study stents included BMS, paclitaxel-eluting (PES), sirolimus-eluting (SES), endeavor zotarolimus-eluting (ZES-E), cobalt-chromium everolimus-eluting (CoCr-EES), platinium-chromium everolimus-eluting (PtCr-EES), resolute zotarolimus-eluting (ZES-R), and BP biolimus-eluting stents (BP-BES). After a systematic electronic search, 113 trials with 90 584 patients were selected. The principal endpoint was definite or probable stent thrombosis (ST) defined according to the Academic Research Consortium within 1 year. Biodegradable polymer-biolimus-eluting stents [OR, 0.56; 95% credible interval (CrI), 0.33-0.90], SES (OR, 0.53; 95% CrI, 0.38-0.73), CoCr-EES (OR, 0.34; 95% CrI, 0.23-0.52), and PtCr-EES (OR, 0.31; 95% CrI, 0.10-0.90) were all superior to BMS in terms of definite or probable ST within 1 year. Cobalt-chromium everolimus-eluting stents demonstrated the lowest risk of ST of all stents at all times after stent implantation. Biodegradable polymer-biolimus-eluting stents was associated with a higher risk of definite or probable ST than CoCr-EES (OR, 1.72; 95% CrI, 1.04-2.98). All DES reduced the need for repeat revascularization, and all but PES reduced the risk of myocardial infarction compared with BMS. All DESs but PES and ZES-E were superior to BMS in terms of ST within 1 year. Cobalt-chromium everolimus-eluting stents was safer than any DES even including BP-BES. Our results suggest that not only the biodegradability of polymer, but the optimal combination of stent alloy, design, strut thickness, polymer, and drug all combined determine the safety of DES.

Lignes directrices canadiennes sur l’utilisation sécuritaire et efficace des opioïdes pour la douleur chronique non cancéreuse

PubMed Central

Kahan, Meldon; Wilson, Lynn; Mailis-Gagnon, Angela; Srivastava, Anita

2011-01-01

Résumé Objectif Présenter aux médecins de famille un résumé clinique pratique sur la prescription d’opioïdes à des populations particulières en se fondant sur les recommandations faites dans les lignes directrices canadiennes sur l’utilisation sécuritaire et efficace des opioïdes pour la douleur chronique non cancéreuse. Qualité des données Pour produire les lignes directrices, les chercheurs ont effectué une synthèse critique de la littérature médicale en insistant plus précisément sur les études de l’efficacité et de la sécurité des opioïdes dans des populations particulières. Message principal Les médecins de famille peuvent atténuer les risques de surdose, de sédation, d’usage abusif et de dépendance grâce à des stratégies adaptées à l’âge et à l’état de santé des patients. Dans le cas de patients à risque de dépendance, on devrait réserver les opioïdes aux douleurs nociceptives ou neuropathiques bien définies qui n’ont pas répondu aux traitements de première intention. Il faut procéder lentement au titrage des opioïdes, avec des dispensations fréquentes et une étroite surveillance pour dépister tout signe d’usage abusif. Une dépendance aux opioïdes suspectée est prise en charge au moyen d’une thérapie structurée aux opioïdes, d’un traitement à la méthadone ou à la buprénorphine ou encore d’un traitement fondé sur l’abstinence. Les patients souffrant de troubles de l’humeur ou d’anxiété ont tendance à avoir une réponse analgésique atténuée aux opioïdes, sont à risque plus élevé d’usage abusif et prennent souvent des sédatifs qui interagissent défavorablement avec les opioïdes. Il faut prendre des précautions semblables à celles utilisées avec d’autres patients à risque élevé. Il faut faire un sevrage progressif si la douleur du patient demeure sévère même avec un essai adéquat de thérapie aux opioïdes. Chez les personnes âgées, la sédation, les chutes et la surdose peuvent être minimisées en utilisant des doses initiales faibles, un titrage plus lent, un sevrage des benzodiazépines et une bonne éducation des patients. Dans le cas des femmes enceintes qui prennent des opioïdes chaque jour, il faut faire un sevrage progressif et cesser complètement. Si ce n’est pas possible, il faut administrer la dose efficace la plus faible. Les femmes enceintes qui ont une dépendance aux opioïdes devraient recevoir un traitement à la méthadone. Les adolescents sont à risque élevé de surdose d’opioïdes, d’usage abusif et de dépendance. Les patients qui ont des adolescents qui vivent à la maison devraient entreposer leurs opioïdes dans un lieu sûr. Les adolescents ont rarement besoin d’une thérapie à long terme aux opioïdes. Conclusion Les médecins de famille doivent tenir compte de l’âge, de la condition psychiatrique, du degré de risque de dépendance du patient et d’autres facteurs quand ils prescrivent des opioïdes pour la douleur chronique.

Validation Data for Mechanical System Algorithms Used in Building Energy Analysis Programs.

DTIC Science & Technology

1982-02-01

15 Zone Design 15 Built-Up Air Handler 15 Ventilation Requirements 16 The DES 16 Duct Design 17 Air -Delivery System 17 VAV Operation 17 Constant Volume...observed to operate well at reduced air flows, even at low flow in the so- called surge region. Recommendations 1. The HVAC system and component...With Inlet Guide Vanes Operating Within a Built-Up Air Handler 31 Test 2 -- Boiler Operation, Capacity, Efficiency, and Stand-By Losses 32 Test 3

Performance Evaluation Within CASE_ATTI of MHT and JVC Association Algorithms for COMDAT TD

DTIC Science & Technology

2007-05-01

les résultats du travail effectué dans le cadre de l’analyse de sensibilité des algorithmes uti- lisés dans COMDAT, comparativement à ceux...is also very important in tracking system. Neverthe- less, tracking performance with even the best designed filter may become very degraded in the...for completeness. 2.2 IMM Some practical model of target motion is assumed for the design of the Kalman filter. This target kinematics model is

Interfacing with Legacy using Remote Method Invocation

NASA Technical Reports Server (NTRS)

Howard, Scott M.

1998-01-01

The assignment described was enough to make a neophyte Java developer bolt for the door: provide a remote method for use by an applet which invokes a native method that wraps a function in an existing legacy library. The purpose of the remote method is to return an instance of a class object whose contents reflect the data structure returned by the legacy function. While embroiled in implementation, I would have spent the time wading through their JNI use group archive as well, but I couldn't seem to locate one. Subsequently, I made the decision to try to document my findings in order to assist others. Before we start on the class design, let's look at what the existing legacy code does. The C function to be called, Get-Legacy-Data, consists of two steps: an ASII file is read from the local disk and its contents are parsed into a Legacy_Type structure whose address is passed as an argument by the caller. The legacy code was compiled into a shared object library, legacy. so, using the IRIX 6.2 compiler and then loaded onto the Web server, a Silicon Graphics Indy station loaded with the IRIX 6.4 operating system. As far as the class design is concerned, the first thing required is a class to act as a template for the data structure returned by the legacy function. This class, JLegacy, declares a series of public instance variables which correspond to the members of Legacy_Type and provides a parameterless constructor. This constructor is never called, not even by the native method which allocates the object for return to the remote method. Next, the remote interface declaration for the remote object must be defined. In order for JLegacyRO to implement getJLegacy, JLegacyRO must interface with the existing legacy code through a native method, getn. getn is declared in the JLegacyRO class but implemented in C, just like the legacy code. getn returns a JLegacy instance and is declared static since its implementation is the same for all instances of the JLegacyRO class.

Revisiting the role of durable polymers in cardiovascular devices.

PubMed

Mori, Hiroyoshi; Otsuka, Fumiyuki; Gupta, Anuj; Jinnouchi, Hiroyuki; Torii, Sho; Harari, Emanuel; Virmani, Renu; Finn, Aloke V

2017-11-01

Polymers are an essential component of drug-eluting stents (DES) used to control drug release but remain the most controversial component of DES technology. There are two types of polymers employed in DES: durable polymer based DES (DP-DES) and biodegradable polymer DES (BP-DES). First-generation DES were exclusively composed of DP and demonstrated increased rates of late stent failure due in part to poor polymer biocompatibility. Newer generations DES use more biocompatible durable polymers or biodegradable polymers. Areas covered: We will cover issues identified with 1st-generation DP-DES, areas of success and failure in 2nd-generation DP-DES and examine the promise and shortcomings of BP-DES. Briefly, fluorinated polymers used in 2nd-generation DP-DES have excellent anti-thrombogenicity and better biocompatibility than 1st-generation DES polymers. However, these devices lead to persistent drug exposure to the endothelium which impairs endothelial function and predisposes towards neoatherosclerosis. Meanwhile, BP-DES has shortened the duration of drug exposure which might be beneficial for endothelial functional recovery leading to less neoatherosclerosis. However, it remains uncertain whether the long-term biocompatibility of bare metal surfaces is better than that of polymer-coated metals. Expert commentary: Each technology has distinct advantages, which can be optimized depending upon the particular characteristics of the patient being treated.

Declarative and Non-declarative Memory Consolidation in Children with Sleep Disorder.

PubMed

Csábi, Eszter; Benedek, Pálma; Janacsek, Karolina; Zavecz, Zsófia; Katona, Gábor; Nemeth, Dezso

2015-01-01

Healthy sleep is essential in children's cognitive, behavioral, and emotional development. However, remarkably little is known about the influence of sleep disorders on different memory processes in childhood. Such data could give us a deeper insight into the effect of sleep on the developing brain and memory functions and how the relationship between sleep and memory changes from childhood to adulthood. In the present study we examined the effect of sleep disorder on declarative and non-declarative memory consolidation by testing children with sleep-disordered breathing (SDB) which is characterized by disrupted sleep structure. We used a story recall task to measure declarative memory and Alternating Serial Reaction time (ASRT) task to assess non-declarative memory. This task enables us to measure two aspects of non-declarative memory, namely general motor skill learning and sequence-specific learning. There were two sessions: a learning phase and a testing phase, separated by a 12 h offline period with sleep. Our data showed that children with SDB exhibited a generally lower declarative memory performance both in the learning and testing phase; however, both the SDB and control groups exhibited retention of the previously recalled items after the offline period. Here we showed intact non-declarative consolidation in SDB group in both sequence-specific and general motor skill. These findings suggest that sleep disorders in childhood have a differential effect on different memory processes (online vs. offline) and give us insight into how sleep disturbances affects developing brain.

Declarative and Non-declarative Memory Consolidation in Children with Sleep Disorder

PubMed Central

Csábi, Eszter; Benedek, Pálma; Janacsek, Karolina; Zavecz, Zsófia; Katona, Gábor; Nemeth, Dezso

2016-01-01

Healthy sleep is essential in children’s cognitive, behavioral, and emotional development. However, remarkably little is known about the influence of sleep disorders on different memory processes in childhood. Such data could give us a deeper insight into the effect of sleep on the developing brain and memory functions and how the relationship between sleep and memory changes from childhood to adulthood. In the present study we examined the effect of sleep disorder on declarative and non-declarative memory consolidation by testing children with sleep-disordered breathing (SDB) which is characterized by disrupted sleep structure. We used a story recall task to measure declarative memory and Alternating Serial Reaction time (ASRT) task to assess non-declarative memory. This task enables us to measure two aspects of non-declarative memory, namely general motor skill learning and sequence-specific learning. There were two sessions: a learning phase and a testing phase, separated by a 12 h offline period with sleep. Our data showed that children with SDB exhibited a generally lower declarative memory performance both in the learning and testing phase; however, both the SDB and control groups exhibited retention of the previously recalled items after the offline period. Here we showed intact non-declarative consolidation in SDB group in both sequence-specific and general motor skill. These findings suggest that sleep disorders in childhood have a differential effect on different memory processes (online vs. offline) and give us insight into how sleep disturbances affects developing brain. PMID:26793090

Etude numerique et experimentale de la reponse vibro-acoustique des structures raidies a des excitations aeriennes et solidiennes

NASA Astrophysics Data System (ADS)

Mejdi, Abderrazak

Les fuselages des avions sont generalement en aluminium ou en composite renforces par des raidisseurs longitudinaux (lisses) et transversaux (cadres). Les raidisseurs peuvent etre metalliques ou en composite. Durant leurs differentes phases de vol, les structures d'avions sont soumises a des excitations aeriennes (couche limite turbulente : TBL, champs diffus : DAF) sur la peau exterieure dont l'energie acoustique produite se transmet a l'interieur de la cabine. Les moteurs, montes sur la structure, produisent une excitation solidienne significative. Ce projet a pour objectifs de developper et de mettre en place des strategies de modelisations des fuselages d'avions soumises a des excitations aeriennes et solidiennes. Tous d'abord, une mise a jour des modeles existants de la TBL apparait dans le deuxieme chapitre afin de mieux les classer. Les proprietes de la reponse vibro-acoustique des structures planes finies et infinies sont analysees. Dans le troisieme chapitre, les hypotheses sur lesquelles sont bases les modeles existants concernant les structures metalliques orthogonalement raidies soumises a des excitations mecaniques, DAF et TBL sont reexamines en premier lieu. Ensuite, une modelisation fine et fiable de ces structures est developpee. Le modele est valide numeriquement a l'aide des methodes des elements finis (FEM) et de frontiere (BEM). Des tests de validations experimentales sont realises sur des panneaux d'avions fournis par des societes aeronautiques. Au quatrieme chapitre, une extension vers les structures composites renforcees par des raidisseurs aussi en composites et de formes complexes est etablie. Un modele analytique simple est egalement implemente et valide numeriquement. Au cinquieme chapitre, la modelisation des structures raidies periodiques en composites est beaucoup plus raffinee par la prise en compte des effets de couplage des deplacements planes et transversaux. L'effet de taille des structures finies periodiques est egalement pris en compte. Les modeles developpes ont permis de conduire plusieurs etudes parametriques sur les proprietes vibro-acoustiques des structures d'avions facilitant ainsi la tache des concepteurs. Dans le cadre de cette these, un article a ete publie dans le Journal of Sound and Vibration et trois autres soumis, respectivement aux Journal of Acoustical Society of America, International Journal of Solid Mechanics et au Journal of Sound and Vibration Mots cles : structures raidies, composites, vibro-acoustique, perte par transmission.

Retour vers le futur: l'expérience des patients et le lien avec la qualité, la sécurité et le rendement financier.

PubMed

Cochrane, Bonnie S; Hagins, Mitch; King, John A; Picciano, Gino; McCafferty, Maureen M; Nelson, Brian

2015-11-01

Au Canada, l'amélioration de l'expérience des patients est devenue une priorité des politiques de santé. Le perfectionnement et la normalisation des outils et systèmes pour surveiller les mesures de l'expérience des patients augmentent, tandis que la tendance vers une plus grande reddition de compte sur des améliorations durables et abordables se confirme. Pour de nombreux professionnels de la santé, ce phénomène fait foi d'un intérêt renouvelé pour les besoins et priorités fondamentaux des patients, après des décennies où les changements structurels et technologiques ont dominé les programmes de santé. Pour les leaders en santé canadiens, l'amélioration de l'expérience des patients comporte actuellement de grands défis et de belles possibilités. À cet égard, l'expérience des organisations partenaires du groupe Studer au Canada est à la fois pertinente et instructive. Ces organisations ont adopté un modèle, du nom de Evidence-Based Leadership (EBL, ou leadership fondé sur des données probantes), qui favorise et soutient l'harmonisation de l'ensemble des activités et des comportements, conformément à des objectifs organisationnels précis, y compris des améliorations mesurables de l'expérience des patients. Le présent article expose des études de cas d'organisations qui ont adopté l'EBL. Ces organisations ont réalisé des progrès rapides en matière d'indicateurs de l'expérience des patients, ainsi que dans des secteurs essentiels comme les résultats cliniques, la sécurité et le rendement financier. Les données émergentes sur les facteurs et processus qui sous-tendent ces améliorations sont également abordées. © 2015 Collège canadien des leaders en santé

Report on the emergency response to the event on May 14, 1997, at the plutonuim reclamation facility, Hanford Site, Richland,Washington

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shoop, D.S.

1997-08-20

On the evening of May 14,1997, a chemical explosion Occurred at the Plutonium Reclamation Facility (PRF) in the 200 West Area(200-W) of the Hanford Site. The event warranted the declaration of an Alert emergency, activation of the Hanford Emergency Response Organization (BRO), and notification of offsite agencies. As a result of the emergency declaration, a subsequent evaluation was conducted to assess: 9 the performance of the emergency response organization o the occupational health response related to emergency activities o event notifications to offsite and environmental agencies. Additionally, the evaluation was designed to: 9 document the chronology of emergency and occupationalmore » health responses and environmental notifications connected with the explosion at the facility 0 assess the adequacy of the Hanford Site emergency preparedness activities; response readiness; and emergency management actions, occupational health, and environmental actions 0 provide an analysis of the causes of the deficiencies and weaknesses in the preparedness and response system that have been identified in the evaluation of the response a assign organizational responsibility to correct deficiencies and weaknesses a improve future performance 0 adjust elements of emergency implementing procedures and emergency preparedness activities.« less

Procedural learning and dyslexia.

PubMed

Nicolson, R I; Fawcett, A J; Brookes, R L; Needle, J

2010-08-01

Three major 'neural systems', specialized for different types of information processing, are the sensory, declarative, and procedural systems. It has been proposed (Trends Neurosci., 30(4), 135-141) that dyslexia may be attributable to impaired function in the procedural system together with intact declarative function. We provide a brief overview of the increasing evidence relating to the hypothesis, noting that the framework involves two main claims: first that 'neural systems' provides a productive level of description avoiding the underspecificity of cognitive descriptions and the overspecificity of brain structural accounts; and second that a distinctive feature of procedural learning is its extended time course, covering from minutes to months. In this article, we focus on the second claim. Three studies-speeded single word reading, long-term response learning, and overnight skill consolidation-are reviewed which together provide clear evidence of difficulties in procedural learning for individuals with dyslexia, even when the tasks are outside the literacy domain. The educational implications of the results are then discussed, and in particular the potential difficulties that impaired overnight procedural consolidation would entail. It is proposed that response to intervention could be better predicted if diagnostic tests on the different forms of learning were first undertaken. 2010 John Wiley & Sons, Ltd.

Declarative and nondeclarative memory: multiple brain systems supporting learning and memory.

PubMed

Squire, L R

1992-01-01

Abstract The topic of multiple forms of memory is considered from a biological point of view. Fact-and-event (declarative, explicit) memory is contrasted with a collection of non conscious (non-declarative, implicit) memory abilities including skills and habits, priming, and simple conditioning. Recent evidence is reviewed indicating that declarative and non declarative forms of memory have different operating characteristics and depend on separate brain systems. A brain-systems framework for understanding memory phenomena is developed in light of lesion studies involving rats, monkeys, and humans, as well as recent studies with normal humans using the divided visual field technique, event-related potentials, and positron emission tomography (PET).

Subthalamic stimulation differentially modulates declarative and nondeclarative memory.

PubMed

Hälbig, Thomas D; Gruber, Doreen; Kopp, Ute A; Scherer, Peter; Schneider, Gerd-Helge; Trottenberg, Thomas; Arnold, Guy; Kupsch, Andreas

2004-03-01

Declarative memory has been reported to rely on the medial temporal lobe system, whereas non-declarative memory depends on basal ganglia structures. We investigated the functional role of the subthalamic nucleus (STN), a structure closely connected with the basal ganglia for both types of memory. Via deep brain high frequency stimulation (DBS) we manipulated neural activity of the STN in humans. We found that DBS-STN differentially modulated memory performance: declarative memory was impaired, whereas non-declarative memory was improved in the presence of STN-DBS indicating a specific role of the STN in the activation of memory systems. Copyright 2004 Lippincott Williams & Wilkins

Declarative memory and skill-related knowledge: Evidence from a case study of amnesia and implications for theories of memory.

PubMed

Gregory, Emma; McCloskey, Michael; Ovans, Zoe; Landau, Barbara

2016-01-01

Theoretical and empirical studies of memory have long been framed by a distinction between declarative and non-declarative memory. We question the sharpness of the distinction by reporting evidence from amnesic L.S.J., who despite retrograde memory losses in declarative knowledge domains, shows sparing of declarative knowledge related to premorbid skill (e.g., playing an instrument). We previously showed that L.S.J. had severe losses of retrograde declarative knowledge across areas of premorbid expertise (e.g., artists of famous works) and everyday knowledge (e.g., company names for logos). Here we present evidence that L.S.J. has sparing of what we call skill-related declarative knowledge, in four domains in which she had premorbid skill (art, music, aviation, driving). L.S.J.'s pattern of loss and sparing raises questions about the strict separation between classically-defined memory types and aligns with a recent proposal by Stanley and Krakauer [2013. Motor skill depends on knowledge of facts. Frontiers in Human Neuroscience, 7,1-11].

The linguistic roots of natural pedagogy.

PubMed

Mattos, Otávio; Hinzen, Wolfram

2015-01-01

Natural pedagogy is a human-specific capacity that allows us to acquire cultural information from communication even before the emergence of the first words, encompassing three core elements: (i) a sensitivity to ostensive signals like eye contact that indicate to infants that they are being addressed through communication, (ii) a subsequent referential expectation (satisfied by the use of declarative gestures) and (iii) a biased interpretation of ostensive-referential communication as conveying relevant information about the referent's kind (Csibra and Gergely, 2006, 2009, 2011). Remarkably, the link between natural pedagogy and another human-specific capacity, namely language, has rarely been investigated in detail. We here argue that children's production and comprehension of declarative gestures around 10 months of age are in fact expressions of an evolving faculty of language. Through both declarative gestures and ostensive signals, infants can assign the roles of third, second, and first person, building the 'deictic space' that grounds both natural pedagogy and language use. Secondly, we argue that the emergence of two kinds of linguistic structures (i.e., proto-determiner phrases and proto-sentences) in the one-word period sheds light on the different kinds of information that children can acquire or convey at different stages of development (namely, generic knowledge about kinds and knowledge about particular events/actions/state of affairs, respectively). Furthermore, the development of nominal and temporal reference in speech allows children to cognize information in terms of spatial and temporal relations. In this way, natural pedagogy transpires as an inherent aspect of our faculty of language, rather than as an independent adaptation that pre-dates language in evolution or development (Csibra and Gergely, 2006). This hypothesis is further testable through predictions it makes on the different linguistic profiles of toddlers with developmental disorders.

The linguistic roots of natural pedagogy

PubMed Central

Mattos, Otávio; Hinzen, Wolfram

2015-01-01

Natural pedagogy is a human-specific capacity that allows us to acquire cultural information from communication even before the emergence of the first words, encompassing three core elements: (i) a sensitivity to ostensive signals like eye contact that indicate to infants that they are being addressed through communication, (ii) a subsequent referential expectation (satisfied by the use of declarative gestures) and (iii) a biased interpretation of ostensive-referential communication as conveying relevant information about the referent’s kind (Csibra and Gergely, 2006, 2009, 2011). Remarkably, the link between natural pedagogy and another human-specific capacity, namely language, has rarely been investigated in detail. We here argue that children’s production and comprehension of declarative gestures around 10 months of age are in fact expressions of an evolving faculty of language. Through both declarative gestures and ostensive signals, infants can assign the roles of third, second, and first person, building the ‘deictic space’ that grounds both natural pedagogy and language use. Secondly, we argue that the emergence of two kinds of linguistic structures (i.e., proto-determiner phrases and proto-sentences) in the one-word period sheds light on the different kinds of information that children can acquire or convey at different stages of development (namely, generic knowledge about kinds and knowledge about particular events/actions/state of affairs, respectively). Furthermore, the development of nominal and temporal reference in speech allows children to cognize information in terms of spatial and temporal relations. In this way, natural pedagogy transpires as an inherent aspect of our faculty of language, rather than as an independent adaptation that pre-dates language in evolution or development (Csibra and Gergely, 2006). This hypothesis is further testable through predictions it makes on the different linguistic profiles of toddlers with developmental disorders. PMID:26441794

76 FR 56856 - New York Disaster Number NY-00108

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-14

... SMALL BUSINESS ADMINISTRATION [Disaster Declaration 12776 and 12777] New York Disaster Number NY... the Presidential declaration of a major disaster for the State of New York (FEMA-4020-DR), dated 08/31... declaration [[Page 56857

40 CFR 52.2900 - Negative declaration.

Code of Federal Regulations, 2010 CFR

2010-07-01

... § 52.2900 Negative declaration. (a) Air Pollution Implementation Plan for the Commonwealth of the... declaration indicating no major lead sources and continued attainment and maintenance of the National Standards for lead. [51 FR 40799, Nov. 10, 1986] ...

Declarative memory performance is associated with the number of sleep spindles in elderly women.

PubMed

Seeck-Hirschner, Mareen; Baier, Paul Christian; Weinhold, Sara Lena; Dittmar, Manuela; Heiermann, Steffanie; Aldenhoff, Josef B; Göder, Robert

2012-09-01

Recent evidence suggests that the sleep-dependent consolidation of declarative memory relies on the nonrapid eye movement rather than the rapid eye movement phase of sleep. In addition, it is known that aging is accompanied by changes in sleep and memory processes. Hence, the purpose of this study was to investigate the overnight consolidation of declarative memory in healthy elderly women. Sleep laboratory of University. Nineteen healthy elderly women (age range: 61-74 years). We used laboratory-based measures of sleep. To test declarative memory, the Rey-Osterrieth Complex Figure Test was performed. Declarative memory performance in elderly women was associated with Stage 2 sleep spindle density. Women characterized by high memory performance exhibited significantly higher numbers of sleep spindles and higher spindle density compared with women with generally low memory performance. The data strongly support theories suggesting a link between sleep spindle activity and declarative memory consolidation.

Preface: Materiaux 2010

NASA Astrophysics Data System (ADS)

Cheikhrouhou, Abdelwaheb

2012-02-01

The national conference 'MATERIAUX 2010', which took place in Mahdia (Tunisia), from 4-7 November 2010 was organized by The 'Tunisian Materials Research Society: Tu-MRS' in collaboration with the Materials Physics Laboratory of Sfax 'LPM', Faculty of Sciences, Sfax University and the Research Unit ' Physique, Informatique et Mathématiques ', Faculty of Sciences, Gafsa University The First National Conference on Materials 'MATERIAUX 2006' was organized in Douz (Tunisia) in December 2006. This was followed by 'MATERIAUX 2007' held in Hammamet (Tunisia) in April 2007 and the National Conference 'MATERIAUX 2009' organized jointly with the Second 'Journées Internationales de la Physique des Matériaux et Applications: JIPMA 2009' in Gafsa (Tunisia) from 20-24 December 2009. 'MATERIAUX 2010' is intended to provide an excellent opportunity for National, Maghreb and International researchers to make their own work on materials known to a wider audience and to have discussions with other participants. This conference will also be an opportunity to exchange experiences, create and consolidate cooperation between different research structures in the Maghreb countries and also the countries around the Mediterranean. This conference will equally promote research development, contribution to collaboration between universities and the socio-economical milieu. More than 300 senior researchers, Professors, PhD and Masters students attended this conference from Tunisia, Algeria, Morocco, France, Spain and Canada. Several researchers, engineers and managers from industrial firms also attended. The conference consisted of plenary talks (8), oral contributions (40) and poster presentations (250). The topics of the Conference were: Nano-materials, nano-systems, thin films, surfaces and interfaces, applications Multifunctionnal materials, magnetic materials, dielectric materials, superconducting materials, applications,... Materials for electronics, informatics and communication Ceramics, glasses, polymers Natural materials (phosphates, clay,...) Metallic materials, alloys, metallurgy,... Others (materials and environment, materials and energy, biomaterials,...) I want to thank the scientific committee, the organizing committee, the local committee and everyone who contributed to the organization of this meeting for their invaluable efforts in order to guarantee the complete success of this conference. Abdelwaheb Cheikhrouhou President of 'Tu-MRS' Chairman of the Conference 'MATERIAUX 2010' Conference photograph Committies Organizing Committee Chairman CHEIKHROUHOU Abdelwaheb (Faculté des Sciences de Sfax) Members ALAYA Sahbi (Faculté des Sciences de Gabès) BENNACEUR Raouf (Faculté des Sciences de Tunis) BEN SALEM Mohamed (Faculté des Sciences de Bizerte) CHEIKHROUHOU-KOUBAA Wissem (Faculté des Sciences de Sfax) EL JANI Belgacem (Faculté des Sciences de Monastir) EZZAOUIA Hatem (Centre de Recherches et de Technologies de l'Energie, Technopole de Borj Cédria) LAMLOUMI Jilani (Ecole Supérieure des Sciences et Techniques de Tunis) REZIG Bahri (Ecole Nationale d'Ingénieurs de Tunis) Local Committee Chairman CHEIKHROUHOU Abdelwaheb (Faculté des Sciences de Sfax) Members CHEIKHROUHOU-KOUBAA Wissem (Faculté des Sciences de Sfax) KOUBAA Mohamed (Institut Supérieur de Biotechnologie de Sfax) NJEH Anwar (Institut Préparatoire aux Etudes d'Ingénieurs de Sfax) BEN SALAH Issam (Faculté des Sciences de Sfax) TAKKALI Férid (Faculté des Sciences de Sfax) REGAIEG Yassin (Faculté des Sciences de Sfax) OTHMANI Safa (Faculté des Sciences de Sfax) MNASSRI Rafik (Faculté des Sciences de Sfax) Secretariat BEN GHOZLEN Afifa (Faculté des Sciences de Sfax) BOUGHARIOU Sana (Faculté des Sciences de Sfax) Scientific Committee M. ADDOU, Faculté des Sciences de Kénitra (Morocco) N. AMDOUNI, Faculté des Sciences de Tunis (Tunisia) M. BACCOUCHE, Faculté des Sciences d'Annaba (Algeria) H. BATIS, Faculté des Sciences de Tunis (Tunisia) A. BELAFHAL, Faculté des Sciences d'El Jadida (Morocco) M.H. BEN GHOZLEN, Faculté des Sciences de Sfax (Tunisia) R. BENNACEUR, Faculté des Sciences de Tunis (Tunisia) B. BENYOUCEF, Université Abou Bakr Belkaid, Tlemcen (Algeria) M. BEN SALEM, Faculté des Sciences de Bizerte (Tunisia) B. BESSAIES, Centre de Recherches et Technologies de l'Energie (Tunisia) H. BOUCHRIHA, Faculté des Sciences de Tunis (Tunisia) W. BOUJELBEN, Faculté des Sciences de Sfax (Tunisia) A. CHEIKHROUHOU, Faculté des Sciences de Sfax (Tunisia) W. CHEIKHROUHOU-KOUBAA, Faculté des Sciences de Sfax (Tunisia) R. CHTOUROU, Centre de Recherches et Technologies de l'Energie (Tunisia) M. DEBBABI, Ecole Nationale d'Ingénieurs de Monastir (Tunisia) A. DAKHLAOUI, Faculté des Sciences de Bizerte (Tunisia) A. DINIA, Université de Strasbourg (France) B. ELJANI, Faculté des Sciences de Monastir (Tunisia) A. ELJAZOULI, Faculté des Sciences Ben Msik, Casablanca (Morocco) Z. FAKHFAKH, Faculté des Sciences de Sfax (Tunisia) A. GASMI, Faculté des Sciences d'Annaba (Algeria) A. GHARBI, Faculté des Sciences de Tunis (Tunisia) R. GHARBI, Faculté des Sciences de Sfax (Tunisia) K. GUIDARA, Faculté des Sciences de Sfax (Tunisia) H. GUERMAZI, Institut Préparatoire aux Etudes d'Ingénieurs de Sfax (Tunisia) S. GUERMAZI, Faculté des Sciences de Sfax (Tunisia) M. HADDAD, Faculté des Sciences de Meknès (Morocco) A. HAJ AMARA, Faculté des Sciences de Bizerte (Tunisia) D. HAMANA, Faculté des Sciences de Constantine (Algeria) N. KAMOUN, Faculté des Sciences de Tunis (Tunisia) S. KADDOUR-CHARFI, Faculté des Sciences de Tunis (Tunisia) M. KADDOUR, Faculté des Sciences de Sfax (Tunisia) M. KHITOUNI, Faculté des Sciences de Sfax (Tunisia) T. MHIRI, Faculté des Sciences de Sfax (Tunisia) Y. MLIK, Institut Préparatoire aux Etudes Scientifiques et Techniques (Tunisia) N. MLIKI, Faculté des Sciences de Tunis (Tunisia) A. NJAH, Faculté des Sciences de Gafsa (Tunisia) M. OUESLATI, Faculté des Sciences de Tunis (Tunisia) K. ZELLAMA, Faculté des Sciences d'Amiens (France) Invited Speakers AMMAR-MERIAH Souad, ITODYS, Université Paris Diderot (France) BEN SALEM Mohamed, Faculté des Sciences de Bizerte, Université du 7 Novembre á Carthage (Tunisia) CHEIKHROUHOU Abdelwaheb, Faculté des Sciences de Sfax, Université de Sfax (Tunisia) DAKHLAOUI Amel, Faculté des Sciences de Bizerte, Université du 7 Novembre á Carthage (Tunisia) DJABBAR Ahmed, Université des Sciences et des Technologies de Lille (France) DURASTANTI Félix, Centre d'Etudes et Recherche en Thermique, Environnement et Systèmes (C.E.R.T.E.S.), Université Paris Est- Créteil (France) FERY-FORGUES Suzanne, Université Paul Sabatier, Toulouse (France) GIRAUD Romain, Laboratoire de Photonique et de Nanostructures, CNRS/LPN, Marcoussis (France)

Les effets des interfaces sur les proprietes magnetiques et de transport des multicouches nickel/iron et cobalt/silver

NASA Astrophysics Data System (ADS)

Veres, Teodor

Cette these est consacree a l'etude de l'evolution structurale des proprietes magnetiques et de transport des multicouches Ni/Fe et nanostructures a base de Co et de l'Ag. Dans une premiere partie, essentiellement bibliographique, nous introduisons quelques concepts de base relies aux proprietes magnetiques et de transport des multicouches metalliques. Ensuite, nous presentons une breve description des methodes d'analyse des resultats. La deuxieme partie est consacree a l'etude des proprietes magnetiques et de transport des multicouches ferromagnetiques/ferromagnetiques Ni/Fe. Nous montrerons qu'une interpretation coherente de ces proprietes necessite la prise en consideration des effets des interfaces. Nous nous attacherons a mettre en evidence, a evaluer et a etudier les effets de ces interfaces ainsi que leur evolution, et ce, suite a des traitements thermiques tel que le depot a temperature elevee et l'irradiation ionique. Les analyses correlees de la structure et de la magnetoresistance nous permettront d'emettre des conclusions sur l'influence des couches tampons entre l'interface et le substrat ainsi qu'entre les couches elles-memes sur le comportement magnetique des couches F/F. La troisieme partie est consacree aux systemes a Magneto-Resistance Geante (MRG) a base de Co et Ag. Nous allons etudier l'evolution de la microstructure suite a l'irradiation avec des ions Si+ ayant une energie de 1 MeV, ainsi que les effets de ces changements sur le comportement magnetique. Cette partie debutera par l'analyse des proprietes d'une multicouche hybride, intermediaire entre les multicouches et les materiaux granulaires. Nous analyserons a l'aide des mesures de diffraction, de relaxation superparamagnetique et de magnetoresistance, les evolutions structurales produites par l'irradiation ionique. Nous etablirons des modeles qui nous aideront a interpreter les resultats pour une serie des multicouches qui couvrent un large eventail de differents comportements magnetiques et ceci en fonction de l'epaisseur de la couche magnetique de Co. Nous verrons que dans ces systemes les effets de l'irradiation ionique sont fortement influences par l'energie de surface ainsi que par l'enthalpie de formation, largement positive pour le systeme Co/Ag.

High frequency of fumigants and other toxic gases in imported freight containers--an underestimated occupational and community health risk.

PubMed

Baur, Xaver; Poschadel, Bernd; Budnik, Lygia Therese

2010-03-01

Residues of pesticide fumigants and toxic industrial chemicals in freight containers represent a health hazard to employees and consumers, especially since freight containers are sealed for transport and distributed widely throughout the importing countries before being opened for unloading. We investigated 2113 freight containers arriving at the second largest container terminal in Europe, Hamburg, Germany, over a 10-week period in 2006. The countries of origin, type of contents and the pesticide fumigation history declared on labels attached to the container were recorded. We determined that 1478 (70%) containers were contaminated with toxic chemicals above chronic reference exposure levels; 761 (36%) even exceeded the higher acute reference exposure level thresholds. Benzene and/or formaldehyde contamination was 4-times greater than for fumigants. Our findings indicate a health risk for dockworkers, container unloaders and even end-consumers, especially as many of the cancerogenic or toxic gases elude subjective detection.

Similarities in human visual and declared measures of preference for opposite-sex faces.

PubMed

Griffey, Jack A F; Little, Anthony C

2014-01-01

Facial appearance in humans is associated with attraction and mate choice. Numerous studies have identified that adults display directional preferences for certain facial traits including symmetry, averageness, and sexually dimorphic traits. Typically, studies measuring human preference for these traits examine declared (e.g., choice or ratings of attractiveness) or visual preferences (e.g., looking time) of participants. However, the extent to which visual and declared preferences correspond remains relatively untested. In order to evaluate the relationship between these measures we examined visual and declared preferences displayed by men and women for opposite-sex faces manipulated across three dimensions (symmetry, averageness, and masculinity) and compared preferences from each method. Results indicated that participants displayed significant visual and declared preferences for symmetrical, average, and appropriately sexually dimorphic faces. We also found that declared and visual preferences correlated weakly but significantly. These data indicate that visual and declared preferences for manipulated facial stimuli produce similar directional preferences across participants and are also correlated with one another within participants. Both methods therefore may be considered appropriate to measure human preferences. However, while both methods appear likely to generate similar patterns of preference at the sample level, the weak nature of the correlation between visual and declared preferences in our data suggests some caution in assuming visual preferences are the same as declared preferences at the individual level. Because there are positive and negative factors in both methods for measuring preference, we suggest that a combined approach is most useful in outlining population level preferences for traits.

Donors' blood group declaration before donation can be used as a tool for electronic crossmatching.

PubMed

Arslan, O

2005-12-01

Electronic crossmatching (E-XM) is used to detect ABO incompatibility. In developing countries, as many of the donations are from first-time donors, it is difficult to guarantee the accuracy of the ABO/Rh label on these units to use them for E-XM. This problem was overcome with a new software 'hemosoft', using donors' blood group declaration before donation as a tool for E-XM. During registration, donors either declare their blood group or give no comment. For, ABO/Rh grouping, either two results from different donations or only one in concordant with the declaration before donation is needed. If there is a conflict, second typing is performed from the unit segment. If donors give no declaration, two different technicians perform typing, one from the sample tube and the other from the unit segment. Of 18,618 donations performed, 640 (3%) were repeated and the rest were first-time donations. In 16,327, typing was performed once, as the blood group declaration and the typing results were identical. In 2407, grouping was performed twice, as donors gave no declaration or conflicts between declaration and typing results were found. No labelling or wrong unit-release errors were detected in units donated, typed and labelled in our centre. In 26,402 donations, 16,314 (61.8%) E-XMs were performed. No major haemolytic transfusion reaction was recorded. Donors' ABO/Rh declaration before donation can be used as a tool for E-XM, instead of the requirement for serological confirmation or a second donation to guarantee grouping.

Fiabilité des structures mécaniques adaptatives: effet de la panne des actionneurs ou des capteurs sur la stabilité

NASA Astrophysics Data System (ADS)

Fall, H.; Charon, W.; Kouta, R.

2002-12-01

Ces dernières décennies, des activités significatives dans le monde étaient dirigées autour du contrôle actif. Le but de ces recherches était essentiellement d'améliorer les performances, la fiabilité et la sécurité des systèmes. Notamment dans le cas des structures soumises à des vibrations aléatoires. D'importants travaux ont été consacré à l'utilisation des “matériaux intelligents” comme capteurs et actionneurs. Cette article propose l'analyse de la fiabilité des systèmes mécaniques en étudiant les pannes des actionneurs ou des capteurs. L'effet de ces pannes sur la stabilité et la performance du système y est démontré. Les méthodologies de conception y sont rappelées. Des exemples numériques sont fournis à travers le contrôle d'un panneau sous chargement dynamique pour illustrer la méthode proposée.

40 CFR 52.122 - Negative declarations.

Code of Federal Regulations, 2010 CFR

2010-07-01

...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Arizona § 52.122 Negative declarations. (a) The following... negative declarations are approved as additional information to the State Implementation Plan. (1) Maricopa... Operations, Rubber Tire Manufacturing, Polymer Manufacturing, Industrial Wastewater, Ship Building and Repair...

40 CFR 52.122 - Negative declarations.

Code of Federal Regulations, 2012 CFR

2012-07-01

...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Arizona § 52.122 Negative declarations. (a) The following... negative declarations are approved as additional information to the State Implementation Plan. (1) Maricopa... Operations, Rubber Tire Manufacturing, Polymer Manufacturing, Industrial Wastewater, Ship Building and Repair...

40 CFR 52.122 - Negative declarations.

Code of Federal Regulations, 2013 CFR

2013-07-01

...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Arizona § 52.122 Negative declarations. (a) The following... negative declarations are approved as additional information to the State Implementation Plan. (1) Maricopa... Operations, Rubber Tire Manufacturing, Polymer Manufacturing, Industrial Wastewater, Ship Building and Repair...

40 CFR 52.122 - Negative declarations.

Code of Federal Regulations, 2014 CFR

2014-07-01

...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Arizona § 52.122 Negative declarations. (a) The following... negative declarations are approved as additional information to the State Implementation Plan. (1) Maricopa... Operations, Rubber Tire Manufacturing, Polymer Manufacturing, Industrial Wastewater, Ship Building and Repair...

40 CFR 52.122 - Negative declarations.

Code of Federal Regulations, 2011 CFR

2011-07-01

...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Arizona § 52.122 Negative declarations. (a) The following... negative declarations are approved as additional information to the State Implementation Plan. (1) Maricopa... Operations, Rubber Tire Manufacturing, Polymer Manufacturing, Industrial Wastewater, Ship Building and Repair...

Diethylstilbestrol-Induced Mouse Hypospadias: “Window of Susceptibility”

PubMed Central

Sinclair, Adriane Watkins; Cao, Mei; Baskin, Laurence; Cunha, Gerald R.

2016-01-01

Hypospadias, an abnormality affecting the penile urethra, is one of the most prevalent congenital malformations afflicting human males. The morphology of hypospadias is markedly different in humans versus mice reflecting substantial differences in penile development in humans and mice. Estrogens such as diethylstilbestrol (DES) elicit mouse penile malformations, but the types of penile abnormalities differ depending on whether DES treatment is prenatal or neonatal. To define the actual “window of susceptibility” to the adverse effects of DES, pregnant mice and their neonatal pups were injected subcutaneously with 200ng/gbw DES every other day from embryonic day 12 to 18 (DES E12-E18), postnatal day 0 to 10 (DES P0-P10), embryonic day 12 to postnatal day 10 (DES E12 to P10), postnatal day 5 to 15 (DES P5 to P15), and postnatal day 10 to 20 (DES P10 to P20). Aged-matched controls received sesame oil vehicle. After euthanasia at 10, 15, 20 and 60 days, penises were analyzed by gross morphology, histology and morphometry. Penises of all 5 groups of DES-treated mice were reduced in size, which was confirmed by morphometric analysis of internal penile structures. The most profound effects were seen in the DES E12-P10, DES P0-P10, and DES P5-P15 groups, thus defining a DES “programming window”. For all parameters, DES treatment from P10-P20 showed the most mild of effects. Adverse effects of DES on the MUMP cartilage and erectile bodies observed shortly after the last DES injection reverted to normality in the DES P5-P15, but not in the E12-P10 and P0-P10 groups, in which MUMP cartilage and erectile body malformations persisted into adulthood, again emphasizing a “window of susceptibility” in the early neonatal period. PMID:26810244

La manucure et la pédicure dans la ville de Ouagadougou (Burkina Faso): pratiques et risqué

PubMed Central

Korsaga-Somé, Nina; Andonaba, Jean Baptiste; Ouédraogo, Muriel Sidnoma; Tapsoba, Gilbert Patrice; Ilboudo, Léopold; Savadogo, Cérina; Barro-Traoré, Fatou; Niamba, Pascal; Traoré, Adama

2016-01-01

La manucure-pédicure est l'ensemble des soins esthétiques des mains, des pieds et des ongles. Au Burkina Faso, l'usage des produits de manucure-pédicure, les techniques utilisées ainsi que les risques encourus restent méconnus. L'objectif de notre étude était d’évaluer la pratique de la manucure-pédicure dans la ville de Ouagadougou. Nous avons mené une étude transversale descriptive de décembre 2010 à novembre 2012 incluant tout les praticiens ayant au moins six mois d'expérience dans l'activité et les clients présents sur les lieux au moment de l'enquête. Nous avons interrogé au total 313 praticiens et 313 clients. L’âge moyen des praticiens était de 19 ans et celui des clients de 32,2 ans. Les praticiens fixes étaient en majorité des femmes (96,87%), ceux mobiles surtout des hommes (68,37%), et 64,53% des clients étaient des femmes. Le pourcentage de praticiens n'ayant pas reçu de formation professionnelle était de 93,92%. 29,7% des praticiens faisaient tremper les instruments pendant au moins dix minutes dans de l'eau de javel; 75,71% savaient que l'utilisation de certains outils étaient dangereux et 26,51% étaient avaient présenté des effets secondaires. Parmi les clients, 40,25% savaient que le matériel utilisé comportait des risques et 30,35% avaient été victimes d'accidents. Les soins de manucure et de pédicure se font dans les salons de coiffure par des coiffeuses non formées à l'exercice de la profession La provenance et la composition des produits n'est pas connues. Des produits non recommandés sont utilisés (shampooing pour trempage des pieds, lame de rasoir et ciseaux pour raclage des pieds). Le recours à la manucure et/ou pédicure est parfois nécessaire mais cela ne doit pas faire perdre de vue les risques encourus. Une sensibilisation des clients et une formation des praticiens semblent nécessaires pour minimiser les risques. PMID:27642448

Signed reward prediction errors drive declarative learning

PubMed Central

Naert, Lien; Janssens, Clio; Talsma, Durk; Van Opstal, Filip; Verguts, Tom

2018-01-01

Reward prediction errors (RPEs) are thought to drive learning. This has been established in procedural learning (e.g., classical and operant conditioning). However, empirical evidence on whether RPEs drive declarative learning–a quintessentially human form of learning–remains surprisingly absent. We therefore coupled RPEs to the acquisition of Dutch-Swahili word pairs in a declarative learning paradigm. Signed RPEs (SRPEs; “better-than-expected” signals) during declarative learning improved recognition in a follow-up test, with increasingly positive RPEs leading to better recognition. In addition, classic declarative memory mechanisms such as time-on-task failed to explain recognition performance. The beneficial effect of SRPEs on recognition was subsequently affirmed in a replication study with visual stimuli. PMID:29293493

Signed reward prediction errors drive declarative learning.

PubMed

De Loof, Esther; Ergo, Kate; Naert, Lien; Janssens, Clio; Talsma, Durk; Van Opstal, Filip; Verguts, Tom

2018-01-01

Reward prediction errors (RPEs) are thought to drive learning. This has been established in procedural learning (e.g., classical and operant conditioning). However, empirical evidence on whether RPEs drive declarative learning-a quintessentially human form of learning-remains surprisingly absent. We therefore coupled RPEs to the acquisition of Dutch-Swahili word pairs in a declarative learning paradigm. Signed RPEs (SRPEs; "better-than-expected" signals) during declarative learning improved recognition in a follow-up test, with increasingly positive RPEs leading to better recognition. In addition, classic declarative memory mechanisms such as time-on-task failed to explain recognition performance. The beneficial effect of SRPEs on recognition was subsequently affirmed in a replication study with visual stimuli.

La prise en charge des troubles de santé mentale par les omnipraticiens du Québec

PubMed Central

Fleury, Marie-Josée; Farand, Lambert; Aubé, Denise; Imboua, Armelle

2012-01-01

Résumé Objectif Cette recherche vise à documenter la prise en charge des troubles mentaux (TM) par les omnipraticiens. Type d’étude Il s’agit d’une étude mixte intégrant un questionnaire auto-administré et des entrevues qualitatives. La banque de données administratives des actes médicaux de la Régie de l’assurance maladie du Québec a aussi été analysée. Contexte La province de Québec. Participants Un total de 1415 omnipraticiens de différents lieux de pratiques ont été sollicités pour le questionnaire; 970 ont été rejoints. Un sous-groupe de 60 omnipraticiens a été rejoint pour les entrevues. Principaux paramètres à l'étude La prévalence annuelle des consultations reliées à des TM courants (TMC) ou graves (TMG), les pratiques cliniques, les pratiques de collaboration, les facteurs facilitant ou entravant la prise en charge des TM, ainsi que les recommandations pour l’amélioration du système de soins. Résultats Le taux de réponse a été de 41% (n = 398 omnipraticiens) pour le questionnaire et de 63% (n = 60) pour les entrevues. Environ 25 % des visites chez les omnipraticiens sont associées à des TM. Presque tous les omnipraticiens prennent en charge des TMC et se sentent compétents pour le faire, à l’inverse de la situation retrouvée pour les TMG. Près de 20 % des TMC sont référés (principalement à des intervenants psychosociaux), alors que près de 75 % des TMG sont référés (surtout en psychiatrie et à l’urgence). Plus de 50 % des omnipraticiens affirment n’entretenir aucun contact avec l’une ou l’autre des ressources de santé mentale. Plusieurs facteurs influencent la prise en charge des TM: les profils des patients (complexité des TM, troubles concomitants); les caractéristiques des omnipraticiens (réseau informel, formation); la culture professionnelle (travail en silo, mécanismes cliniques formalisés); le milieu institutionnel (multidisciplinarité, salariat); l’organisation des services (ressources; coordination formalisée) et l’environnement (politiques). Conclusion Le rôle clé des omnipraticiens et leur soutien à la prise en charge des TM ont été démontrés, spécifiquement pour les TMC. Pour une prise en charge optimale des soins primaires de santé mentale, des stratégies à composantes multiples, dont les soins partagés, devraient être davantage déployées.

On the front lines in Coalinga

USGS Publications Warehouse

Marcussen, G.

1984-01-01

Actually, the first step is to declare an emergency. The city council can ratify it later. The declaration is in your emergency preparedness plan, if you can find it. Mine was under a pile of debris; but after, I turned it up, I located an old declaration from a flood disaster and inserted the word "earthquake" wherever I found the word "flood." The declaration is necessary to give the city some protection from liability, which unfortunately, it will need. 

[Selective alteration of the declarative memory systems in patients treated with a high number of electroconvulsive therapy sessions].

PubMed

Rami-González, L; Boget-Llucià, T; Bernardo, M; Marcos, T; Cañizares-Alejos, S; Penadés, R; Portella, M J; Castelví, M; Raspall, T; Salamero, M

The reversible electrochemical effects of electroconvulsive therapy (ECT) on specific areas of the brain enable the neuroanatomical bases of some cognitive functions to be studied. In research carried out on memory systems, a selective alteration of the declarative ones has been observed after treatment with ECT. Little work has been done to explore the differential alteration of the memory subsystems in patients with a high number of ECT sessions. AIM. To study the declarative and non declarative memory system in psychiatric patients submitted to maintenance ECT treatment, with a high number of previous ECT sessions. 20 patients submitted to treatment with ECT (10 diagnosed as having depression and 10 with schizophrenia) and 20 controls, who were paired by age, sex and psychopathological diagnosis. For the evaluation of the declarative memory system, the Wechsler Memory Scale (WMS) logical memory test was used. The Hanoi Tower procedural test was employed to evaluate the non declarative system. Patients treated with ECT performed worse in the WMS logical memory test, but this was only significant in patients diagnosed as suffering from depression. No significant differences were observed in the Hanoi Tower test. A selective alteration of the declarative systems was observed in patients who had been treated with a high number of ECT sessions, while the non declarative memory systems remain unaffected.

Public Health Aspects of Global Population Health and Well-being in the 21st Century Regarding Determinants of Health.

PubMed

Masic, Izet

2018-01-01

Why did I recall the details about public health aspects of global population and well-being in the 21 st century regarding the determinants of health? Most of all because today, at the end of 2017, we are talking about the same principles from the "Declaration on Primary Health Care" from 1978, and the same goals as those in "Health for all" which are still current or perhaps even more current than when they were published for the first time in scientific and professional literature. This is a notorious fact, even though we are talking about "Global Health" and its determinants, in all countries of the world, regardless of their social wealth, and all existing resources, especially those, intended to organize health care. In the field of practice, public health has advanced in knowledge and methodology. Biomedical scientists have identified many causes of infectious diseases and developed methods to put them under control. Epidemiologists have identified risk factors that favor many chronic illnesses and information that can be used to reduce the risk of disease. Efforts to cleanse the environment have resulted in air and water that are far safer than half a century ago. Intensive educational efforts have convinced the health-care organizers to improve their health behavior that is to quit tobacco use, and a combination of drinking and driving. The ability to assess the populations' health behaviors and assess the share of health interventions has also significantly improved the availability of health-care databases and computer software capable of analyzing them. However, much of the targets from the World Health Organization declarations are not improved or in some countries provided by official institutions responsible for public health activities.

Effets de la formation sur la violence conjugale

PubMed Central

Zaher, Eman; Keogh, Kelly; Ratnapalan, Savithiri

2014-01-01

Résumé Objectif Décrire et évaluer l’efficacité de la formation concernant la violence conjugale pour améliorer les connaissances et permettre la reconnaissance et la prise en charge par les médecins des femmes victimes de violence. Sources des données On a fait une recension dans la base de données des révisions systématiques de Cochrane, MEDLINE, PubMed, PsycINFO, ERIC et EMBASE pour trouver des articles publiés entre le 1e janvier 2000 et le 1e novembre 2012. Des recherches manuelles ont complété cette recension pour cerner des articles pertinents à l’aide d’une stratégie de recherche combinant des textes, mots et expressions MeSH. Sélection des études On a choisi des études randomisées contrôlées qui portaient sur des interventions éducatives à l’intention des médecins et fournissaient des données sur les effets des interventions. Synthèse On a inclus 9 études randomisées contrôlées qui décrivaient différentes approches pédagogiques et diverses mesures des résultats. Trois études examinaient les effets d’interventions éducatives pour des médecins en formation postdoctorale et ont constaté une augmentation des connaissances, mais il n’y a eu aucun changement dans le comportement en ce qui a trait à l’identification des victimes de violence conjugale. Six études portaient sur des interventions éducatives pour des médecins en pratique active. Trois d’entre elles utilisaient une approche à multiples facettes pour les médecins, qui combinait une formation ainsi que des interventions de soutien de la part du système pour changer les comportements des médecins, comme une sensibilisation générale accrue à la violence conjugale au moyen de brochures et d’affiches, des aide-mémoire pour rappeler aux médecins comment identifier les victimes, des moyens pour faciliter l’accès des médecins à des services de soutien pour les victimes, la réalisation d’audits et la fourniture de rétroaction. Les interventions éducatives à multiples facettes prenaient la forme d’ateliers interactifs, d’apprentissage sur le web et de formation expérientielle. Une autre étude utilisait des discussions de groupes témoins et de la formation et a permis de constater une amélioration dans le signalement de la violence conjugale par les médecins. Les 2 autres études ont relevé une meilleure perception par les médecins en pratique de leur confiance en eux à l’aide d’apprentissage par problèmes en ligne. Conclusion Il a été difficile de déterminer quelle stratégie pédagogique était la plus efficace étant donné que les interventions éducatives et les mesures des résultats variaient entre les études choisies. De brèves interventions pour les médecins en formation postdoctorale amélioraient les connaissances mais ne semblaient pas influencer les comportements. La formation en ligne sous forme d’apprentissage par problèmes améliorait les perceptions des médecins en pratique, leurs connaissances et leurs habiletés quant à la prise en charge de la violence conjugale. La formation des médecins combinée à des interventions de soutien de la part du système semblait bénéfique aux victimes de violence conjugale et augmentait le nombre de demandes de consultations auprès des ressources de soutien à leur intention.

Robust misinterpretation of confidence intervals.

PubMed

Hoekstra, Rink; Morey, Richard D; Rouder, Jeffrey N; Wagenmakers, Eric-Jan

2014-10-01

Null hypothesis significance testing (NHST) is undoubtedly the most common inferential technique used to justify claims in the social sciences. However, even staunch defenders of NHST agree that its outcomes are often misinterpreted. Confidence intervals (CIs) have frequently been proposed as a more useful alternative to NHST, and their use is strongly encouraged in the APA Manual. Nevertheless, little is known about how researchers interpret CIs. In this study, 120 researchers and 442 students-all in the field of psychology-were asked to assess the truth value of six particular statements involving different interpretations of a CI. Although all six statements were false, both researchers and students endorsed, on average, more than three statements, indicating a gross misunderstanding of CIs. Self-declared experience with statistics was not related to researchers' performance, and, even more surprisingly, researchers hardly outperformed the students, even though the students had not received any education on statistical inference whatsoever. Our findings suggest that many researchers do not know the correct interpretation of a CI. The misunderstandings surrounding p-values and CIs are particularly unfortunate because they constitute the main tools by which psychologists draw conclusions from data.

La prévention de l’étouffement et de la suffocation chez les enfants

PubMed Central

Cyr, Claude

2012-01-01

RÉSUMÉ L’étouffement, la suffocation et la strangulation sont responsables de graves blessures non intentionnelles chez les enfants et constituent des causes importantes de décès non intentionnels chez les nourrissons et les tout-petits. Presque la totalité des décès et des blessures attribuables à un étouffement, une suffocation ou une strangulation sont évitables. Le présent document de principes traite des définitions, de l’épidémiologie et des stratégies de prévention efficaces de ces blessures. Des recommandations qui combinent des démarches pour améliorer la sécurité, incluant des recherches, de la surveillance, des lois et des normes, la conception des produits et l’éducation, sont présentées. Les dispensateurs de soins pédiatriques devraient encourager les parents et autres personnes qui s’occupent d’enfants à apprendre la réanimation cardiorespiratoire (RCR) et les premiers soins en cas d’étouffement, et leur offrir des conseils préventifs adaptés à l’âge de leur enfant lors des bilans de santé réguliers afin de prévenir ces blessures.

Measuring Effects and Success in Influence Operations: Challenges, Limitations and Opportunitites

DTIC Science & Technology

2011-04-01

domaines de la psychologie , de l’anthropologie et de la sociologie, ainsi que sur des entrevues menées auprès de pionniers des technologies de...documents issus des domaines de la psychologie , de l’anthropologie et de la sociologie, ainsi que sur des entrevues menées auprès de pionniers des...la psychologie , de l’anthropologie et de la sociologie, ainsi que sur des entrevues menées auprès de pionniers des technologies de l’intelligence

New European initiatives in colorectal cancer screening: Budapest Declaration. Official appeal during the Hungarian Presidency of the Council of the European Union under the Auspices of the United European Gastroenterology Federation, the European Association for Gastroenterology and Endoscopy and the Hungarian Society of Gastroenterology.

PubMed

Wittmann, Tibor; Stockbrugger, Reinhold; Herszényi, László; Jonkers, Daisy; Molnár, Béla; Saurin, Jean-Christophe; Regula, Jaroslaw; Malesci, Alberto; Laghi, Luigi; Pintér, Tamás; Teleky, Béla; Dítě, Petr; Tulassay, Zsolt

2012-01-01

Colorectal cancer (CRC) is the second most common newly diagnosed cancer and the second most common cause of death in the European Union (EU). CRC is an enormous health and economic burden. Early detection and prevention have the possibility of reducing this burden significantly. Many cancer-associated deaths can be avoided through early detection by high-quality colorectal screening programs followed by appropriate treatment. Under the auspices of the United European Gastroenterology Federation (UEGF), the European Association for Gastroenterology and Endoscopy, the Hungarian Society of Gastroenterology and the Hungarian College of Gastroenterology, the 'Budapest Declaration' (2011) was an accepted official scientific program during the Hungarian Presidency of the Council of the European Union. The Budapest Declaration follows the Munich Declaration (2001), the Brussels Declaration (2007), the Transatlantic Declaration (2009), the Barcelona Declaration (2010), the written declaration of CRC screening, a joint initiative with European Parliamentarians coordinated by the UEGF, and finally, the 'European Guidelines for Quality Assurance in Colorectal Cancer Screening and Diagnosis'. The 'Budapest Declaration' together with previous declarations aims to urge the national and supranational healthcare decision makers to launch new Europe-wide initiatives to establish high-quality CRC programs to achieve optimal efficiency in CRC screening. In case of implementation of the proposals, actions and conditions recommended, we can achieve that one of the basic principles of the EU - the chance of equal access - be realized in member states with respect to the prevention of CRC and reduction of cancer-related mortality. To better achieve this goal, we propose to establish an UEGF joint committee, with one participant representing each EU member state to coordinate and supervise the implementation of CRC screening. Copyright © 2012 S. Karger AG, Basel.

Implementation Cryptography Data Encryption Standard (DES) and Triple Data Encryption Standard (3DES) Method in Communication System Based Near Field Communication (NFC)

NASA Astrophysics Data System (ADS)

Ratnadewi; Pramono Adhie, Roy; Hutama, Yonatan; Saleh Ahmar, A.; Setiawan, M. I.

2018-01-01

Cryptography is a method used to create secure communication by manipulating sent messages during the communication occurred so only intended party that can know the content of that messages. Some of the most commonly used cryptography methods to protect sent messages, especially in the form of text, are DES and 3DES cryptography method. This research will explain the DES and 3DES cryptography method and its use for stored data security in smart cards that working in the NFC-based communication system. Several things that will be explained in this research is the ways of working of DES and 3DES cryptography method in doing the protection process of a data and software engineering through the creation of application using C++ programming language to realize and test the performance of DES and 3DES cryptography method in encrypted data writing process to smart cards and decrypted data reading process from smart cards. The execution time of the entering and the reading process data using a smart card DES cryptography method is faster than using 3DES cryptography.

76 FR 26749 - New Mexico; Amendment No. 2 to Notice of a Major Disaster Declaration

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-09

... notice of a major disaster declaration for the State of New Mexico (FEMA-1962-DR), DATED March 24, 2011... declaration of March 24, 2011. The Pueblo of Acoma for Public Assistance. The following Catalog of Federal...

76 FR 23614 - New Mexico; Amendment No. 1 to Notice of a Major Disaster Declaration

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-27

... notice of a major disaster declaration for the State of New Mexico (FEMA-1962-DR), dated March 24, 2011... declaration of March 24, 2011. The Pueblos of Picuris, Pojoaque, San Felipe, and Santa Clara for Public...

76 FR 66110 - Pennsylvania Disaster Number PA-00044

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-25

... SMALL BUSINESS ADMINISTRATION [Disaster Declaration 12822 and 12823] Pennsylvania Disaster Number... amendment of the Presidential declaration of a major disaster for the Commonwealth of Pennsylvania (FEMA... major disaster declaration for the Commonwealth of PENNSYLVANIA, dated 09/12/2011 is hereby amended to...

76 FR 68803 - Pennsylvania Disaster Number PA-00044

Federal Register 2010, 2011, 2012, 2013, 2014

2011-11-07

... SMALL BUSINESS ADMINISTRATION [Disaster Declaration 12822 and 12823] Pennsylvania Disaster Number... amendment of the Presidential declaration of a major disaster for the Commonwealth of Pennsylvania (FEMA... disaster declaration for the State of Pennsylvania, dated 09/12/2011 is hereby amended to include the...

76 FR 61130 - Pennsylvania Disaster Number PA-00044

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-03

... SMALL BUSINESS ADMINISTRATION [Disaster Declaration 12822 and 12823] Pennsylvania Disaster Number... amendment of the Presidential declaration of a major disaster for the Commonwealth of Pennsylvania (FEMA... disaster declaration for the Commonwealth of Pennsylvania, dated 09/12/2011 is hereby amended to include...

40 CFR 62.2400 - Identification of plan-negative declaration.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 8 2011-07-01 2011-07-01 false Identification of plan-negative declaration. 62.2400 Section 62.2400 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR....2400 Identification of plan—negative declaration. Letter from Florida Department of Environmental...

40 CFR 62.7852 - Identification of plan-negative declaration.

Code of Federal Regulations, 2014 CFR

2014-07-01

... Mexico Fluoride Emissions from Primary Aluminum Plants § 62.7852 Identification of plan—negative declaration. The New Mexico Environmental Improvement Division and the Albuquerque Air Pollution Control... declaration. 62.7852 Section 62.7852 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR...

40 CFR 62.7852 - Identification of plan-negative declaration.

Code of Federal Regulations, 2012 CFR

2012-07-01

... Mexico Fluoride Emissions from Primary Aluminum Plants § 62.7852 Identification of plan—negative declaration. The New Mexico Environmental Improvement Division and the Albuquerque Air Pollution Control... declaration. 62.7852 Section 62.7852 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR...

40 CFR 62.7852 - Identification of plan-negative declaration.

Code of Federal Regulations, 2013 CFR

2013-07-01

... Mexico Fluoride Emissions from Primary Aluminum Plants § 62.7852 Identification of plan—negative declaration. The New Mexico Environmental Improvement Division and the Albuquerque Air Pollution Control... declaration. 62.7852 Section 62.7852 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR...

40 CFR 62.7852 - Identification of plan-negative declaration.

Code of Federal Regulations, 2011 CFR

2011-07-01

... Mexico Fluoride Emissions from Primary Aluminum Plants § 62.7852 Identification of plan—negative declaration. The New Mexico Environmental Improvement Division and the Albuquerque Air Pollution Control... declaration. 62.7852 Section 62.7852 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR...

40 CFR 62.7852 - Identification of plan-negative declaration.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Mexico Fluoride Emissions from Primary Aluminum Plants § 62.7852 Identification of plan—negative declaration. The New Mexico Environmental Improvement Division and the Albuquerque Air Pollution Control... declaration. 62.7852 Section 62.7852 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR...

47 CFR 15.101 - Equipment authorization of unintentional radiators.

Code of Federal Regulations, 2014 CFR

2014-10-01

.... TV interface device Declaration of Conformity or Certification. Cable system terminal device Declaration of Conformity. Stand-alone cable input selector switch Verification. Class B personal computers... used with Class B personal computers Declaration of Conformity or Certification. 1 Class B personal...

47 CFR 15.101 - Equipment authorization of unintentional radiators.

Code of Federal Regulations, 2010 CFR

2010-10-01

.... TV interface device Declaration of Conformity or Certification. Cable system terminal device Declaration of Conformity. Stand-alone cable input selector switch Verification. Class B personal computers... used with Class B personal computers Declaration of Conformity or Certification. 1 Class B personal...

47 CFR 15.101 - Equipment authorization of unintentional radiators.

Code of Federal Regulations, 2012 CFR

2012-10-01

.... TV interface device Declaration of Conformity or Certification. Cable system terminal device Declaration of Conformity. Stand-alone cable input selector switch Verification. Class B personal computers... used with Class B personal computers Declaration of Conformity or Certification. 1 Class B personal...

47 CFR 15.101 - Equipment authorization of unintentional radiators.

Code of Federal Regulations, 2011 CFR

2011-10-01

.... TV interface device Declaration of Conformity or Certification. Cable system terminal device Declaration of Conformity. Stand-alone cable input selector switch Verification. Class B personal computers... used with Class B personal computers Declaration of Conformity or Certification. 1 Class B personal...

47 CFR 15.101 - Equipment authorization of unintentional radiators.

Code of Federal Regulations, 2013 CFR

2013-10-01

.... TV interface device Declaration of Conformity or Certification. Cable system terminal device Declaration of Conformity. Stand-alone cable input selector switch Verification. Class B personal computers... used with Class B personal computers Declaration of Conformity or Certification. 1 Class B personal...

Dynamic ambulance reallocation for the reduction of ambulance response times using system status management.

PubMed

Lam, Sean Shao Wei; Zhang, Ji; Zhang, Zhong Cheng; Oh, Hong Choon; Overton, Jerry; Ng, Yih Yng; Ong, Marcus Eng Hock

2015-02-01

Dynamically reassigning ambulance deployment locations throughout a day to balance ambulance availability and demands can be effective in reducing response times. The objectives of this study were to model dynamic ambulance allocation plans in Singapore based on the system status management (SSM) strategy and to evaluate the dynamic deployment plans using a discrete event simulation (DES) model. The geographical information system-based analysis and mathematical programming were used to develop the dynamic ambulance deployment plans for SSM based on ambulance calls data from January 1, 2011, to June 30, 2011. A DES model that incorporated these plans was used to compare the performance of the dynamic SSM strategy against static reallocation policies under various demands and travel time uncertainties. When the deployment plans based on the SSM strategy were followed strictly, the DES model showed that the geographical information system-based plans resulted in approximately 13-second reduction in the median response times compared to the static reallocation policy, whereas the mathematical programming-based plans resulted in approximately a 44-second reduction. The response times and coverage performances were still better than the static policy when reallocations happened for only 60% of all the recommended moves. Dynamically reassigning ambulance deployment locations based on the SSM strategy can result in superior response times and coverage performance compared to static reallocation policies even when the dynamic plans were not followed strictly. Copyright © 2014 Elsevier Inc. All rights reserved.

Voyage dans le noir. Trous noirs, matière noire, énergie noire et antimatière [Journey in the dark. Black holes, dark matter, dark energy and antimatter

ScienceCinema

Alvarez-Gaume, Luis; Doser, Michael; Grojean, Chri

2018-05-24

Et si nous faisions avec les physiciens un voyage dans le noir ? De l'astrophysique à la physique des particules les trois noirs, la matière noire, l'énergie noire ou l’antimatière intriguent et fascinent. Que sont ces objets qui bousculent nos idées et qui véhiculent parfois des craintes irraisonnées? Luis Alvarez-Gaume, Michael Doser et Christophe Grojean, physiciens du CERN vous invitent à mettre en lumière (!) les constituants de base de la matière et à explorer les mystères de la physique contemporaine. Une soirée lumineuse pour éclairer des concepts et ne plus avoir peur du noir. [ What if we made a trip to the physicists in the dark? From astrophysics to particle physics the three blacks, dark matter, dark energy or antimatter intrigue and fascinate. What are these objects that jostle our ideas and sometimes convey irrational fears? Luis Alvarez-Gaume, Michael Doser and Christophe Grojean, CERN physicists invite you to highlight (!) The basic constituents of matter and to explore the mysteries of contemporary physics. A bright evening to illuminate concepts and not be afraid of the dark.

Expression, purification and characterization of two truncated peste des petits ruminants virus matrix proteins in Escherichia coli, and production of polyclonal antibodies against this protein.

PubMed

Liu, Fuxiao; Wu, Xiaodong; Li, Lin; Liu, Zengshan; Wang, Zhiliang

2013-09-01

Peste des petits ruminants virus (PPRV), the etiological agent of peste des petits ruminants, is classified into the genus Morbillivirus in the family Paramyxoviridae. The PPRV matrix (M) gene is composed of 1483 base pairs, encoding a 335 amino acids M protein with a molecular weight of approximately 38kD. We have demonstrated previously that the full-length M protein was expressed at an extremely low level or not even expressed in Escherichia coli BL21 (DE3). In this study, the M protein was split into two truncated forms to be successfully expressed in E. coli at a high level using the pET30a (+) vector, respectively, by analysis of SDS-PAGE, western blot and MALDI-TOF-MS. The optimization of culture conditions led us to perform the recombinant protein induction with 0.2mM IPTG at 28°C for 12h, whereby both proteins nevertheless were expressed in the insoluble form. Therefore, both His-tagged proteins were purified under the denaturing condition using a commercially available kit. Balb/c mice were immunized with the complex of purified proteins and then effectively produced polyclonal antibodies, which reached to a relatively high titer by the analysis of ELISA. The specificity of the prepared polyclonal antibodies was checked by western blot and immunofluorescence, revealing them with the desirable specificity against both non-denatured and denatured M proteins. Copyright © 2013 Elsevier Inc. All rights reserved.

Préoccupations de carrière chez les médecins de travail des groupements de Médecine de travail en Tunisie

PubMed Central

Merchaoui, Irtyah; Chouchène, Asma; Bouanène, Ines; Chaari, Néila; Zrafi, Wassim; Henchi, Adnène; Akrout, Mohamed; Amri, Charfeddine

2017-01-01

Introduction L'insatisfaction de carrière des médecins de travail (MT) peut influencer leur performance et la qualité des prestations fournies. L'objectif de notre étude est d'évaluer la satisfaction au travail des MT du terrain de l'ensemble des Groupements de médecine de travail (GMT) de la Tunisie et préciser les facteurs déterminants. Méthodes Il s'agit d'une étude nationale transversale portant sur les MT de 22 GMT, basée sur le questionnaire, validé SAPHORA JOB. Résultats 58% des MT des GMT étaient insatisfaits de leur carrière. La satisfaction de carrière était statistiquement influencée par le nombre d'entreprises en charge (p=0,016), l'organisation du travail (p=0,010),le ressenti du métier (p=0,011),le salaire (p‹10-3) et l'information sur la réglementation en vigueur (p=0,047). Conclusion L'homogénéisation des grilles salariales et des échelons de carrière des MT des GMT basée sur une révision des textes législatifs est indiquée. L'amélioration de l'organisation et des conditions de travail peut permettre un épanouissement au travail et une amélioration des prestations. PMID:28819472

Lack of involvement of medical writers and the pharmaceutical industry in publications retracted for misconduct: a systematic, controlled, retrospective study.

PubMed

Woolley, Karen L; Lew, Rebecca A; Stretton, Serina; Ely, Julie A; Bramich, Narelle J; Keys, Janelle R; Monk, Julie A; Woolley, Mark J

2011-06-01

The primary objective of this study was to quantify how many publications retracted because of misconduct involved declared medical writers (i.e., not ghostwriters) or declared pharmaceutical industry support. The secondary objective was to investigate factors associated with misconduct retractions. A systematic, controlled, retrospective, bibliometric study. Retracted publications dataset in the MEDLINE database. PubMed was searched (Limits: English, human, January 1966 - February 2008) to identify publications retracted because of misconduct. Publications retracted because of mistake served as the control group. Standardized definitions and data collection tools were used, and data were analyzed by an independent academic statistician. Of the 463 retracted publications retrieved, 213 (46%) were retracted because of misconduct. Publications retracted because of misconduct rarely involved declared medical writers (3/213; 1.4%) or declared pharmaceutical industry support (8/213; 3.8%); no misconduct retractions involved both declared medical writers and the industry. Retraction because of misconduct, rather than mistake, was significantly associated with: absence of declared medical writers (odds ratio: 0.16; 95% confidence interval: 0.05-0.57); absence of declared industry involvement (0.25; 0.11-0.58); single authorship (2.04; 1.01-4.12); first author having at least one other retraction (2.05; 1.35-3.11); and first author affiliated with a low/middle income country (2.34; 1.18-4.63). The main limitations of this study were restricting the search to English-language and human research articles. Publications retracted because of misconduct rarely involved declared medical writers or declared pharmaceutical industry support. Increased attention should focus on factors that are associated with misconduct retractions.

An Analysis of State Public Health Emergency Declarations

PubMed Central

2014-01-01

Disaster responses often involve coordination among multiple levels of government and public and private sector collaboration. When emergencies raise health concerns, governments must include public health and health care systems in their response. A state government’s declaration of “public health emergency” can provide that state’s health sector with flexibility and guidance about response parameters. Although events including Hurricanes Katrina and Sandy and the H1N1 influenza outbreak provided opportunities for states to deploy their public health emergency powers, little has been reported about how states have used their authority to declare a public health emergency. I present a systematic identification and analysis of states’ public health emergency declarations, examine why these declarations were issued, and discuss their potential value. PMID:25033156

78 FR 4966 - Puerto Rico Disaster #PR-00018

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-23

... SMALL BUSINESS ADMINISTRATION [Disaster Declaration 13445 and 13446] Puerto Rico Disaster PR-00018... Administrative declaration of a disaster for the Commonwealth of Puerto Rico dated 01/10/2013. Incident: Tropical... which received an EIDL Declaration is Puerto Rico. (Catalog of Federal Domestic Assistance Numbers 59002...

76 FR 70528 - Pennsylvania Disaster Number PA-00044

Federal Register 2010, 2011, 2012, 2013, 2014

2011-11-14

... SMALL BUSINESS ADMINISTRATION [Disaster Declaration 12822 and 12823] Pennsylvania Disaster Number... amendment of the Presidential declaration of a major disaster for the State of Pennsylvania (FEMA-4030-DR... major disaster declaration for the State of Pennsylvania, dated 09/12/2011 is hereby amended to extend...

76 FR 70527 - Pennsylvania Disaster Number PA-00042

Federal Register 2010, 2011, 2012, 2013, 2014

2011-11-14

... SMALL BUSINESS ADMINISTRATION [Disaster Declaration 12820 and 12821] Pennsylvania Disaster Number... amendment of the Presidential declaration of a major disaster for the State of Pennsylvania (FEMA-4025-DR... major disaster declaration for the State of Pennsylvania, dated 09/12/2011 is hereby amended to extend...

15 CFR 714.4 - Amended declaration or report.

Code of Federal Regulations, 2010 CFR

2010-01-01

...) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE CHEMICAL WEAPONS CONVENTION REGULATIONS ACTIVITIES INVOLVING SCHEDULE 3 CHEMICALS § 714.4 Amended declaration or report. In order for BIS to maintain... following information that you have previously declared or reported: (1) Types of Schedule 3 chemicals...

44 CFR 206.35 - Requests for emergency declarations.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 44 Emergency Management and Assistance 1 2014-10-01 2014-10-01 false Requests for emergency declarations. 206.35 Section 206.35 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF HOMELAND SECURITY DISASTER ASSISTANCE FEDERAL DISASTER ASSISTANCE The Declaration Process § 206...

44 CFR 206.35 - Requests for emergency declarations.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 44 Emergency Management and Assistance 1 2012-10-01 2011-10-01 true Requests for emergency declarations. 206.35 Section 206.35 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF HOMELAND SECURITY DISASTER ASSISTANCE FEDERAL DISASTER ASSISTANCE The Declaration Process § 206...

44 CFR 206.35 - Requests for emergency declarations.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 44 Emergency Management and Assistance 1 2011-10-01 2011-10-01 false Requests for emergency declarations. 206.35 Section 206.35 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF HOMELAND SECURITY DISASTER ASSISTANCE FEDERAL DISASTER ASSISTANCE The Declaration Process § 206...

44 CFR 206.35 - Requests for emergency declarations.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 44 Emergency Management and Assistance 1 2013-10-01 2013-10-01 false Requests for emergency declarations. 206.35 Section 206.35 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF HOMELAND SECURITY DISASTER ASSISTANCE FEDERAL DISASTER ASSISTANCE The Declaration Process § 206...

44 CFR 206.35 - Requests for emergency declarations.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Requests for emergency declarations. 206.35 Section 206.35 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF HOMELAND SECURITY DISASTER ASSISTANCE FEDERAL DISASTER ASSISTANCE The Declaration Process § 206...

40 CFR 62.7860 - Identification of sources-negative declaration.

Code of Federal Regulations, 2013 CFR

2013-07-01

... Mexico Emissions from Existing Large Municipal Waste Combustion Units § 62.7860 Identification of sources—negative declaration. Letter from the City of Albuquerque Air Pollution Control Division dated September 10... declaration. 62.7860 Section 62.7860 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR...

40 CFR 62.7860 - Identification of sources-negative declaration.

Code of Federal Regulations, 2012 CFR

2012-07-01

... Mexico Emissions from Existing Large Municipal Waste Combustion Units § 62.7860 Identification of sources—negative declaration. Letter from the City of Albuquerque Air Pollution Control Division dated September 10... declaration. 62.7860 Section 62.7860 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR...

40 CFR 62.7860 - Identification of sources-negative declaration.

Code of Federal Regulations, 2014 CFR

2014-07-01

... Mexico Emissions from Existing Large Municipal Waste Combustion Units § 62.7860 Identification of sources—negative declaration. Letter from the City of Albuquerque Air Pollution Control Division dated September 10... declaration. 62.7860 Section 62.7860 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR...

37 CFR 41.203 - Declaration.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 37 Patents, Trademarks, and Copyrights 1 2013-07-01 2013-07-01 false Declaration. 41.203 Section 41.203 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND TRADEMARK OFFICE, DEPARTMENT OF COMMERCE PRACTICE BEFORE THE PATENT TRIAL AND APPEAL BOARD Patent Interferences § 41.203 Declaration. (a...

37 CFR 41.203 - Declaration.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 37 Patents, Trademarks, and Copyrights 1 2014-07-01 2014-07-01 false Declaration. 41.203 Section 41.203 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND TRADEMARK OFFICE, DEPARTMENT OF COMMERCE PRACTICE BEFORE THE PATENT TRIAL AND APPEAL BOARD Patent Interferences § 41.203 Declaration. (a...

76 FR 72715 - Agency Information Collection Activities: Cargo Manifest/Declaration, Stow Plan, Container Status...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-11-25

... Activities: Cargo Manifest/ Declaration, Stow Plan, Container Status Messages and Importer Security Filing... concerning the following information collection. Title: Cargo Manifest/Declaration, Stow Plan, Container... and other Federal agencies to comment on an information collection requirement concerning the Cargo...

77 FR 6135 - Agency Information Collection Activities: Cargo Manifest/Declaration, Stow Plan, Container Status...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-07

... Activities: Cargo Manifest/ Declaration, Stow Plan, Container Status Messages and Importer Security Filing... the Paperwork Reduction Act: Cargo Manifest/Declaration, Stow Plan, Container Status Messages and..., mechanical, or other technological techniques or other forms of information. Title: Cargo Manifest...

15 CFR 714.4 - Amended declaration or report.

Code of Federal Regulations, 2011 CFR

2011-01-01

...) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE CHEMICAL WEAPONS CONVENTION REGULATIONS ACTIVITIES INVOLVING SCHEDULE 3 CHEMICALS § 714.4 Amended declaration or report. In order for BIS to maintain... following information that you have previously declared or reported: (1) Types of Schedule 3 chemicals...

Hydrogeology of a fractured shale (Opalinus Clay): Implications for deep geological disposal of radioactive wastes

NASA Astrophysics Data System (ADS)

Gautschi, Andreas

2001-01-01

As part of the Swiss programme for high-level radioactive-waste disposal, a Jurassic shale (Opalinus Clay) is being investigated as a potential host rock. Observations in clay pits and the results of a German research programme focusing on hazardous waste disposal have demonstrated that, at depths of 10-30 m, the permeability of the Opalinus Clay decreases by several orders of magnitude. Hydraulic tests in deeper boreholes (test intervals below 300 m) yielded hydraulic conductivities <10-12 m/s, even though joints and faults were included in some of the test intervals. These measurements are consistent with hydrogeological data from Opalinus Clay sections in ten tunnels in the Folded Jura of northern Switzerland. Despite extensive faulting, only a few indications of minor water inflow were encountered in more than 6,600 m of tunnel. All inflows were in tunnel sections where the overburden is less than 200 m. The hydraulic data are consistent with clay pore-water hydrochemical and isotopic data. The extensive hydrogeological data base - part of which derives from particularly unfavourable geological environments - provides arguments that advective transport through faults and joints is not a critical issue for the suitability of Opalinus Clay as a host rock for deep geological waste disposal. Résumé. Dans le cadre du programme suisse de stockage de déchets hautement radioactifs, une formation argileuse du Jurassique, l'argile à Opalinus, a été étudiée en tant que roche hôte potentielle. Des observations dans des cavités dans l'argile et les résultats du programme de recherche allemand consacré au stockage de déchets à risques ont démontré que, à des profondeur de 10 à 30 m, la perméabilité des argiles à Opalinus décroît de plusieurs ordres de grandeur. Des essais hydrauliques dans des forages plus profonds (intervalles de test á une profondeur de plus de 300 m) ont donné des conductivités hydrauliques inférieures à 10-12 m/s, même lorsque des fractures et des failles existaient dans certains des intervalles d'essais. Ces mesures sont conformes aux données hydrogéologiques tirées du recoupement des argiles à Opalinus par dix tunnels du Jura plissé du nord de la Suisse. Malgré une tectonique intense, peu de manifestations de faibles venues d'eau ont été rencontrées dans plus de 6600 m de tunnel. Toutes les venues d'eau se sont produites dans des sections de tunnel où le recouvrement est inférieur à 200 m. Les données hydrauliques sont en bon accord avec les données hydrochimiques et isotopiques de l'eau porale des argiles. En se basant sur le grand nombre de données hydrogéologiques, qui portent en partie sur les environnements géologiques particulièrement peu propices, on peut avancer que le transport advectif le long des failles et des fractures n'est pas un facteur susceptible de remettre en question le choix de l'argile à Opalinus comme roche hôte pour le stockage de déchets radioactifs en formation géologique profonde. Resúmen. Dentro del programa suizo de eliminación de residuos radiactivos de alta actividad, se está investigando la posibilidad de utilizar unos esquistos Jurásicos (Arcilla Opalina) como depósito geológico. Las observaciones efectuadas en pozos en arcilla y los resultados de un programa de estudio alemán sobre eliminación de residuos peligrosos han demostrado que, a profundidades de entre 10 y 30 m, la permeabilidad de la Arcilla Opalina decrece en varios órdenes de magnitud. Los ensayos hidráulicos realizados en sondeos más profundos (en intervalos situados a más de 300 m) proporcionaron conductividades hidráulicas inferiores a 10-12 m/s, pese a que algunos de los intervalos interceptaban juntas y fallas. Estas medidas son coherentes con los datos hidrogeológicos de las secciones de Arcilla Opalina existentes en 10 túneles del Jurásico Plegado, al norte de Suiza. A pesar de las fallas extensivas, apenas se hallaron indicios de entrada de agua en los más de 6.600 m de túnel. Todos los flujos tenían lugar en secciones del túnel que soportan sobrecargas inferiores a 200 m. Los datos hidráulicos son coherentes con los datos hidroquímicos e isotópicos del agua intersticial de las arcillas. Los abundantes datos hidrogeológicos -parte de los cuales proceden de medios particularmente desfavorables desde el punto de vista geológico- proporcionan argumentos de que el transporte advectivo a través de fallas y juntas no es un aspecto crítico en lo que respecta a la idoneidad de la Arcilla Opalina como almacenamiento geológico profundo de residuos.

An Overview of the Canadian Forces’ Second Generation Capability-Based Planning Analytical Process

DTIC Science & Technology

2010-09-01

gestion et intgration des capacités Feuille de route des capacits stratégiques Produits clès Plan d’investissement Plan de capacités de défense...méthodes de recherche opérationnelle objectives et subjectives permet- tant la mise en œuvre du volet « planification, gestion et intégration des ...pacités, la gestion des capacités et l’intégration des capacités. Le processus comprend des intrants, des méthodes

Paternité des articles et intérêts concurrents : une analyse des recommandations aux auteurs des journaux traitant de pratique pharmaceutique

PubMed Central

Courbon, Ève; Tanguay, Cynthia; Lebel, Denis; Bussières, Jean-François

2014-01-01

RÉSUMÉ Contexte : La présence d’auteurs honorifiques et fantômes ainsi que les intérêts concurrents représentent des difficultés bien documentées, liées à la publication d’articles scientifiques. Il existe des lignes directrices encadrant la rédaction et la publication de manuscrits scientifiques, notamment celles de l’International Committee of Medical Journal Editors (ICMJE). Objectifs : L’objectif principal de cette étude descriptive et transversale visait à recenser les instructions portant sur la paternité des articles et les intérêts concurrents provenant des recommandations aux auteurs des journaux traitant de pratique pharmaceutique. L’objectif secondaire visait à déterminer des mesures correctrices pour une paternité des articles plus transparente. Méthode : La recherche a débuté par l’identification des journaux traitant de pratique pharmaceutique. La consultation des instructions aux auteurs des journaux a permis ensuite de recenser les recommandations destinées à éviter les problèmes de paternité des articles et d’intérêts concurrents. Finalement, les membres de l’équipe de recherche se sont consultés afin de définir des mesures correctrices possibles à l’intention des chercheurs. Résultats : Des 232 journaux traitant de pharmacie, 33 ont été définis comme traitant de pratique pharmaceutique. Un total de 24 (73 %) journaux mentionnaient suivre la politique de l’ICMJE, 14 (42 %) demandaient aux auteurs de remplir un formulaire de déclaration d’intérêts concurrents au moment de la soumission de l’article, 17 (52 %) présentaient une définition de la qualité d’auteur et 5 (15 %) demandaient de détailler les contributions de chaque auteur. Une grille de 40 critères a été élaborée pour définir l’attribution du statut d’auteur. Conclusion : Moins de la moitié des journaux demandait aux auteurs de transmettre un formulaire de déclaration des intérêts concurrents au moment de la soumission d’un article et seulement la moitié des journaux avait donné une définition de la qualité d’auteur. La publication scientifique de travaux sur les pratiques pharmaceutiques n’est pas à l’abri des manques de transparence liés à la publication. L’utilisation d’une grille décrivant la contribution de chaque auteur et la publication en ligne des travaux peuvent contribuer à limiter ces risques. PMID:24970938

Mechanisms and Patterns of Intravascular Ultrasound In-Stent Restenosis Among Bare Metal Stents and First- and Second-Generation Drug-Eluting Stents.

PubMed

Goto, Kosaku; Zhao, Zhijing; Matsumura, Mitsuaki; Dohi, Tomotaka; Kobayashi, Nobuaki; Kirtane, Ajay J; Rabbani, LeRoy E; Collins, Michael B; Parikh, Manish A; Kodali, Susheel K; Leon, Martin B; Moses, Jeffrey W; Mintz, Gary S; Maehara, Akiko

2015-11-01

The most common causes of in-stent restenosis (ISR) are intimal hyperplasia and stent under expansion. The purpose of this study was to use intravascular ultrasound (IVUS) to compare the ISR mechanisms of bare metal stents (BMS), first-generation drug-eluting stents (DES), and second-generation DES. There were 298 ISR lesions including 52 BMS, 73 sirolimus-eluting stents, 52 paclitaxel-eluting stents, 16 zotarolimus-eluting stents, and 105 everolimus-eluting stent. Mean patient age was 66.6 ± 1.1 years, 74.2% were men, and 48.3% had diabetes mellitus. BMS restenosis presented later (70.0 ± 66.7 months) with more intimal hyperplasia compared with DES (BMS 58.6 ± 15.5%, first-generation DES 52.6 ± 20.9%, second-generation DES 48.2 ± 22.2%, p = 0.02). Although reference lumen areas were similar in BMS and first- and second-generation DES, restenotic DES were longer (BMS 21.8 ± 13.5 mm, first-generation DES 29.4 ± 16.1 mm, second-generation DES 32.1 ± 18.7 mm, p = 0.003), and stent areas were smaller (BMS 7.2 ± 2.4 mm(2), first-generation DES 6.1 ± 2.1 mm(2), second-generation DES 5.7 ± 2.0 mm(2), p <0.001). Stent fracture was seen only in DES (first-generation DES 7 [5.0%], second-generation DES 8 [7.4%], p = 0.13). In conclusion, restenotic first- and second-generation DES were characterized by less neointimal hyperplasia, smaller stent areas, longer stent lengths, and more stent fractures than restenotic BMS. Copyright © 2015 Elsevier Inc. All rights reserved.

Report Summary--Rio Political Declaration on Social Determinants of Health: A Snapshot of Canadian Actions 2015.

PubMed

Stankiewicz, A; Herel, M; DesMeules, M

2015-09-01

In 2012, Canada and other United Nations (UN) Member States endorsed the "Rio Political Declaration on Social Determinants of Health" (Rio Declaration), a non-binding pledge which calls on World Health Organization (WHO) Member States to improve/influence the working and living conditions that affect health and well-being. The Rio Declaration sets out actions to address health inequities in five themes: to adopt better governance for health and development; to promote participation in policy making and implementation; to further reorient the health sector towards reducing health inequities; to strengthen global governance and collaboration; and to monitor and increase accountability. In 2013, following the endorsement of the Rio Declaration, the Government of Canada released a report to begin to document Canadian actions related to its five themes. Building on this first report, and in anticipation of WHO reporting on Member State implementation of the Rio Declaration at the May 2015 World Health Assembly, the Government of Canada developed the report, Rio Political Declaration on Social Determinants of Health: A Snapshot of Canadian Actions 2015, which showcases Canada's recent actions since 2013 contributing to the advancement of the five Rio Declaration themes. The report provides a current picture of the diverse spectrum of activities undertaken across levels of government and sectors to advance health equity and address social determinants of health in Canada, and intends to stimulate global and domestic exchange and uptake of promising practices to advance health equity.

Phase transitions and reentrant phenomena in liquid crystals having both rigid and flexible intramolecular joints

NASA Astrophysics Data System (ADS)

Pyżuk, W.; Górecka, E.; Mieczkowski, J.; Przedmojski, J.

1992-07-01

Two series of liquid-crystalline compounds having three phenyl rings separated by flexible spacer —CH(CH{3})CH{2}—COO— and by rigid azo and azoxy group, were studied by DSC, optical and X-ray methods. For esters of dl-3-(4^{prime}-nitro)-phenylbutyric acid with 4^{prime}-alkoxy-phenylazo-phenol-4 having dodecyloxy or longer terminal chains, as well as for related azoxy compounds, a narrow (even below 5 K) reentrant or inverted nematic phase appearing between partly bilayer and monolayer smectics A was observed. For higher homologues of the azoxy series additional smectic phases appear, leading to the occurrence of new multicritical points, e.g. the critical end point Ad Cd N^re. On each of the lines, which separate nematic from smectic A phases, transitions are of weakly first or second-order and more than one tricritical point can occur. On the A{1} N/A{1} N^re line, a simple N A{1} tricritical point is observed at T_NI/T_AN = 0.834. The presence of further critical points depends on the components of the binary system involved. Four of the azoxy compounds studied undergo a second order phase transition between partly bilayer smectics, Ad and Cd. Such a transition is accompanied by a jumb in the specific heat, varying linearly with the length of the molecular tails. Various temperature dependences of the layer spacing in the Ad phase are observed for subsequent homologues from the azoxy series. Plusieurs cristaux liquides composés de trois groupements phényl séparés par un groupement —CH(CH{3})CH{2}—COO—, ainsi que par des groupements azo et azoxy, ont été examinés par AED, méthodes optiques et par rayons X. Pour des esters de l'acide dl-3-(4^{prime}-nitro)phénylbutyrique et de 4^{prime}-alkoxy-phénylazo-phénol-4 ayant comme terminaison une chaîne dodecyloxy ou bien plus longue, ainsi que pour des composés azoxy relatif, on observe (même au-dessous de 5 K) une étroite phase nématique réentrante ou inverse entre les phases smectiques : monocouche et partiellement bicouche. Pour des homologues plus longs dans la série des composés azoxy, on a constaté l'existence d'autres phases smectiques ce qui implique l'apparition, sur les diagrammes des phases, de nouveau points multicritiques, par exemple le point Ad Cd N^re. Sur chaque ligne séparant les phases smectiques A de la phase nématique les transitions sont faiblement du premier ordre ou du deuxième ordre ce qui mène dans certain cas à plus qu'un point tricritique. Sur la ligne A{1} N/A{1} N^re on observe à T_NI/T_AN = 0,834 un simple point tricritique N A{1} — l'apparition des autres dépend du choix des constituants du système binaire. Dans le cas de quatre composés azoxy on a constaté une transition du deuxième ordre entre les phases smectiques partiellement bicouches, Ad et Cd. La transition est accompagnée d'un brusque changement de la chaleur spécifique qui varie linéairement avec la longueur de la queue de la molécule. Pour des homologues suivants de la série des composés azoxy on observe différentes dépendances en température de la distance entre les couches de la phase Ad.

Evaluation of Accessory Lacrimal Gland in Muller’s Muscle Conjunctival Resection Specimens for Precursor Cell Markers and Biological Markers of Dry Eye Disease

PubMed Central

Ali, Marwan; Shah, Dhara; Pasha, Zeeshan; Jassim, Sarmad H.; Jaboori, Assraa Jassim; Setabutr, Pete; Aakalu, Vinay K.

2017-01-01

Purpose The accessory lacrimal glands (ALG) are an understudied component of the tear functional unit, even though they are important in the development of dry eye syndrome (DES). To advance our understanding of aging changes, regenerative potential and histologic correlates to human characteristics, we investigated human ALG tissue from surgical samples to determine the presence or absence of progenitor cell markers and lacrimal epithelial markers and to correlate marker expression to relevant patient characteristics. Materials and Methods ALG tissues obtained from Muller’s Muscle Conjunctival Resection (MMCR) specimens were created using tissue microarrays (TMAs). Immunofluorescence staining of MMCR sections was performed using primary antibodies specific to cell protein markers. Cell marker localization in TMAs was then assessed by two blinded observers using a standardized scoring system. Patient characteristics including age, race, and status of ocular surface health were then compared against expression of stem cell markers. Results Human ALG expressed a number of epithelial markers, and in particular, histatin-1 was well correlated with the expression of epithelial markers and was present in most acini. In addition, we noted the presence of precursor cell markers nestin, ABCG2 and CD90 in ALG tissue. There was a decrease in precursor cell marker expression with increasing age. Finally, we noted that a negative association was present between histatin-1 expression and DES. Conclusions Thus, we report for the first time that human ALG tissues contain precursor marker positive cells and that this marker expression may decrease with increasing age. Moreover, histatin-1 expression may be decreased in DES. Future studies will be performed to use these cell markers to isolate and culture lacrimal epithelial cells from heterogeneous tissues, determine the relevance of histatin-1 expression to DES and isolate candidate precursor cells from ALG tissue. PMID:27612554

Models of the strongly lensed quasar DES J0408−5354

DOE Office of Scientific and Technical Information (OSTI.GOV)

Agnello, A.; et al.

We present gravitational lens models of the multiply imaged quasar DES J0408-5354, recently discovered in the Dark Energy Survey (DES) footprint, with the aim of interpreting its remarkable quad-like configuration. We first model the DES single-epochmore » $grizY$ images as a superposition of a lens galaxy and four point-like objects, obtaining spectral energy distributions (SEDs) and relative positions for the objects. Three of the point sources (A,B,D) have SEDs compatible with the discovery quasar spectra, while the faintest point-like image (G2/C) shows significant reddening and a `grey' dimming of $$\\approx0.8$$mag. In order to understand the lens configuration, we fit different models to the relative positions of A,B,D. Models with just a single deflector predict a fourth image at the location of G2/C but considerably brighter and bluer. The addition of a small satellite galaxy ($$R_{\\rm E}\\approx0.2$$") in the lens plane near the position of G2/C suppresses the flux of the fourth image and can explain both the reddening and grey dimming. All models predict a main deflector with Einstein radius between $1.7"$ and $2.0",$ velocity dispersion $267-280$km/s and enclosed mass $$\\approx 6\\times10^{11}M_{\\odot},$$ even though higher resolution imaging data are needed to break residual degeneracies in model parameters. The longest time-delay (B-A) is estimated as $$\\approx 85$$ (resp. $$\\approx125$$) days by models with (resp. without) a perturber near G2/C. The configuration and predicted time-delays of J0408-5354 make it an excellent target for follow-up aimed at understanding the source quasar host galaxy and substructure in the lens, and measuring cosmological parameters. We also discuss some lessons learnt from J0408-5354 on lensed quasar finding strategies, due to its chromaticity and morphology.« less

Radioligand binding characterization of the bradykinin B(2) receptor in the rabbit and pig ileal smooth muscle.

PubMed

Meini, Stefania; Cucchi, Paola; Catalani, Claudio; Bellucci, Francesca; Santicioli, Paolo; Giuliani, Sandro; Maggi, Carlo Alberto

2010-06-10

Several species-related differences have been reported in kinin B(2) receptor pharmacology. The present study aimed to evaluate the affinity of the bradykinin B(2) receptor antagonist MEN16132 for the rabbit and pig B(2) receptor, and radioligand binding experiments using [(3)H]bradykinin and membranes of rabbit and pig ileum smooth muscle were conducted. The [(3)H]bradykinin binding was characterized by homologous displacement curves indicating K(d) values of 0.65 and 0.33nM in rabbit and pig, respectively. The B(2) receptor specificity of [(3)H]bradykinin binding was shown by the low affinity (>microM) displayed by agonists ([desArg(9)]bradykinin and Lys[desArg(9)]bradykinin) and antagonists [Leu(8),desArg(9)]bradykinin and Lys[Leu(8),desArg(9)]bradykinin) selective for the B(1) receptor. The affinity of MEN16132 and other antagonists was determined by inhibition curves (pK(i) values in the rabbit and pig assay, respectively): MEN16132 (10.4 and 10.3) and peptide compounds such as icatibant (10.1 and 9.9) and MEN11270 (10.3 and 10.1) displayed subnanomolar potency in both assays; the nonpeptide LF16-0687 (8.4 and 8.5) and FR173657 (8.2 and 9.1) exhibited a different affinity pattern, whereas WIN64338 displayed low affinity (5.7 and

76 FR 58557 - New York Disaster Number NY-00109

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-21

... SMALL BUSINESS ADMINISTRATION [Disaster Declaration 12778 and 12779] New York Disaster Number NY... the Presidential declaration of a major disaster for Public Assistance Only for the State of New York... the President's major disaster declaration for Private Non-Profit organizations in the State of New...

76 FR 58558 - New York Disaster Number NY-00109

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-21

... SMALL BUSINESS ADMINISTRATION [Disaster Declaration 12778 and 12779] New York Disaster Number NY... the Presidential declaration of a major disaster for Public Assistance Only for the State of New York... the President's major disaster declaration for Private Non-Profit organizations in the State of New...

77 FR 70203 - New York Disaster Number NY-00131

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-23

... SMALL BUSINESS ADMINISTRATION [Disaster Declaration 13374 and 13375] New York Disaster Number NY... the Presidential declaration of a major disaster for Public Assistance Only for the State of New York... the President's major disaster declaration for Private Non-Profit organizations in the State of NEW...

77 FR 71666 - New York Disaster Number NY-00131

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-03

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76 FR 58559 - New York Disaster Number NY-00109

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-21

... SMALL BUSINESS ADMINISTRATION [Disaster Declaration 12778 and 12779] New York Disaster Number NY... the Presidential declaration of a major disaster for Public Assistance Only for the State of New York... the President's major disaster declaration for Private Non-Profit organizations in the State of New...

76 FR 56855 - New York Disaster Number NY-00109

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-14

... SMALL BUSINESS ADMINISTRATION [Disaster Declaration 12778 and 12779] New York Disaster Number NY... the Presidential declaration of a major disaster for Public Assistance Only for the State of New York... the President's major disaster declaration for Private Non-Profit organizations in the State of New...

77 FR 76587 - New York Disaster Number NY-00131

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-28

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76 FR 59178 - New York Disaster Number NY-00109

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-23

... SMALL BUSINESS ADMINISTRATION [Disaster Declaration 12778 and 12779] New York Disaster Number NY... the Presidential declaration of a major disaster for Public Assistance Only for the State of New York... the President's major disaster declaration for Private Non-Profit organizations in the State of New...

76 FR 59179 - Puerto Rico Disaster Number PR-00014

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-23

... SMALL BUSINESS ADMINISTRATION [Disaster Declaration 12768 and 12769] Puerto Rico Disaster Number... amendment of the Presidential declaration of a major disaster for the Commonwealth of Puerto Rico (FEMA-4017... major disaster declaration for the Commonwealth of Puerto Rico, dated 08/27/2011 is hereby amended to...

76 FR 59179 - Puerto Rico Disaster Number PR-00014

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-23

... SMALL BUSINESS ADMINISTRATION [Disaster Declaration 12768 and 12769] Puerto Rico Disaster Number... amendment of the Presidential declaration of a major disaster for the Commonwealth of Puerto Rico (FEMA-4017... the Presidential disaster declaration for the Commonwealth of PUERTO RICO, dated 08/27/2011 is hereby...

76 FR 67244 - Puerto Rico Disaster Number PR-00014

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-31

... SMALL BUSINESS ADMINISTRATION [Disaster Declaration 12768 and 12769] Puerto Rico Disaster Number... amendment of the Presidential declaration of a major disaster for the Commonwealth of Puerto Rico (FEMA-4017... major disaster declaration for the Commonwealth of Puerto Rico, dated 08/27/2011 is hereby amended to...

75 FR 76746 - Agency Information Collection Activities: Declaration of Ultimate Consignee That Articles Were...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-09

... Activities: Declaration of Ultimate Consignee That Articles Were Exported for Temporary Scientific or... That Articles Were Exported for Temporary Scientific or Educational Purposes. This is a proposed... forms of information. Title: Declaration of Ultimate Consignee That Articles Were Exported for Temporary...

76 FR 27739 - California Disaster #CA-00170 Declaration of Economic Injury

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-12

... Declaration of Economic Injury AGENCY: U.S. Small Business Administration. ACTION: Amendment 1. SUMMARY: This is an amendment to the Economic Injury Disaster Loan (EIDL) declaration for the State of California..., Washington, DC 20416. SUPPLEMENTARY INFORMATION: The notice of the Administrator's economic injury disaster...

76 FR 71057 - Agency Information Collection Activities: Crew's Effects Declaration

Federal Register 2010, 2011, 2012, 2013, 2014

2011-11-16

... Activities: Crew's Effects Declaration AGENCY: U.S. Customs and Border Protection, Department of Homeland... Budget (OMB) for review and approval in accordance with the Paperwork Reduction Act: Crew's Effects... Effects Declaration. OMB Number: 1651-0020. Form Number: CBP Form 1304. Abstract: CBP Form 1304, Crew's...

7 CFR 786.102 - Definitions.

Code of Federal Regulations, 2012 CFR

2012-01-01

... by a natural disaster declaration, and any county contiguous to a county that qualifies by a natural... there is a verifiable sale or delivery record of milk marketed for commercial use. Natural disaster declaration means a natural disaster declaration issued by the Secretary of Agriculture after January 1, 2005...

7 CFR 786.102 - Definitions.

Code of Federal Regulations, 2014 CFR

2014-01-01

... by a natural disaster declaration, and any county contiguous to a county that qualifies by a natural... there is a verifiable sale or delivery record of milk marketed for commercial use. Natural disaster declaration means a natural disaster declaration issued by the Secretary of Agriculture after January 1, 2005...

7 CFR 786.102 - Definitions.

Code of Federal Regulations, 2011 CFR

2011-01-01

... by a natural disaster declaration, and any county contiguous to a county that qualifies by a natural... there is a verifiable sale or delivery record of milk marketed for commercial use. Natural disaster declaration means a natural disaster declaration issued by the Secretary of Agriculture after January 1, 2005...

7 CFR 786.102 - Definitions.

Code of Federal Regulations, 2013 CFR

2013-01-01

... by a natural disaster declaration, and any county contiguous to a county that qualifies by a natural... there is a verifiable sale or delivery record of milk marketed for commercial use. Natural disaster declaration means a natural disaster declaration issued by the Secretary of Agriculture after January 1, 2005...

44 CFR 206.36 - Requests for major disaster declarations.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 44 Emergency Management and Assistance 1 2013-10-01 2013-10-01 false Requests for major disaster declarations. 206.36 Section 206.36 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF HOMELAND SECURITY DISASTER ASSISTANCE FEDERAL DISASTER ASSISTANCE The Declaration Process § 206...

44 CFR 206.36 - Requests for major disaster declarations.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 44 Emergency Management and Assistance 1 2014-10-01 2014-10-01 false Requests for major disaster declarations. 206.36 Section 206.36 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF HOMELAND SECURITY DISASTER ASSISTANCE FEDERAL DISASTER ASSISTANCE The Declaration Process § 206...

44 CFR 206.36 - Requests for major disaster declarations.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 44 Emergency Management and Assistance 1 2011-10-01 2011-10-01 false Requests for major disaster declarations. 206.36 Section 206.36 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF HOMELAND SECURITY DISASTER ASSISTANCE FEDERAL DISASTER ASSISTANCE The Declaration Process § 206...

44 CFR 206.36 - Requests for major disaster declarations.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Requests for major disaster declarations. 206.36 Section 206.36 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF HOMELAND SECURITY DISASTER ASSISTANCE FEDERAL DISASTER ASSISTANCE The Declaration Process § 206...

44 CFR 206.36 - Requests for major disaster declarations.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 44 Emergency Management and Assistance 1 2012-10-01 2011-10-01 true Requests for major disaster declarations. 206.36 Section 206.36 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF HOMELAND SECURITY DISASTER ASSISTANCE FEDERAL DISASTER ASSISTANCE The Declaration Process § 206...

50 CFR 14.64 - Exceptions to export declaration requirements.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 50 Wildlife and Fisheries 1 2010-10-01 2010-10-01 false Exceptions to export declaration requirements. 14.64 Section 14.64 Wildlife and Fisheries UNITED STATES FISH AND WILDLIFE SERVICE, DEPARTMENT OF... OF WILDLIFE AND PLANTS IMPORTATION, EXPORTATION, AND TRANSPORTATION OF WILDLIFE Wildlife Declarations...

50 CFR 14.62 - Exceptions to import declaration requirements.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 50 Wildlife and Fisheries 1 2010-10-01 2010-10-01 false Exceptions to import declaration requirements. 14.62 Section 14.62 Wildlife and Fisheries UNITED STATES FISH AND WILDLIFE SERVICE, DEPARTMENT OF... OF WILDLIFE AND PLANTS IMPORTATION, EXPORTATION, AND TRANSPORTATION OF WILDLIFE Wildlife Declarations...

40 CFR 62.5400 - Identification of plan-negative declaration.

Code of Federal Regulations, 2010 CFR

2010-07-01

... declaration. The State Department of Environmental Quality Engineering submitted on January 18, 1989, a letter... 40 Protection of Environment 8 2010-07-01 2010-07-01 false Identification of plan-negative declaration. 62.5400 Section 62.5400 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR...

40 CFR 62.5375 - Identification of plan-negative declaration.

Code of Federal Regulations, 2010 CFR

2010-07-01

...—negative declaration. The State Department of Environmental Quality Engineering submitted on July 31, 1979... 40 Protection of Environment 8 2010-07-01 2010-07-01 false Identification of plan-negative declaration. 62.5375 Section 62.5375 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR...

40 CFR 62.5350 - Identification of plan-negative declaration.

Code of Federal Regulations, 2010 CFR

2010-07-01

... declaration. The State Department of Environmental Quality Engineering submitted on April 12, 1978, a letter... 40 Protection of Environment 8 2010-07-01 2010-07-01 false Identification of plan-negative declaration. 62.5350 Section 62.5350 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR...

19 CFR 122.83 - Forms required.

Code of Federal Regulations, 2010 CFR

2010-04-01

.... (a) Traveling general declaration and manifest. When applying for examination and release from an airport or place of entry in the U.S., the aircraft commander or agent shall file a traveling general declaration and manifest. The traveling general declaration and manifest is one certified copy of the original...

40 CFR 62.7854 - Identification of plan-negative declaration.

Code of Federal Regulations, 2011 CFR

2011-07-01

... of this chapter. (b) Letter from the City of Albuquerque Air Pollution Control Division dated... declaration. 62.7854 Section 62.7854 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... declaration. (a)The State Department of Health and Social Services submitted on October 31, 1977, a letter...

78 FR 41942 - Alaska; Major Disaster and Related Determinations

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2013-07-12

... President issued a major disaster declaration under the authority of the Robert T. Stafford Disaster Relief... disaster declaration under the Robert T. Stafford Disaster Relief and Emergency Assistance Act, 42 U.S.C...; 97.048, Disaster Housing Assistance to Individuals and Households In Presidentially Declared Disaster...

78 FR 32414 - Illinois; Major Disaster and Related Determinations

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2013-05-30

... President issued a major disaster declaration under the authority of the Robert T. Stafford Disaster Relief... magnitude to warrant a major disaster declaration under the Robert T. Stafford Disaster Relief and Emergency..., Disaster Housing Assistance to Individuals and Households In Presidentially Declared Disaster Areas; 97.049...

75 FR 51834 - Mississippi; Amendment No. 3 to Notice of a Major Disaster Declaration

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-23

... concerning Federal funds provided under the authority of the Robert T. Stafford Disaster Relief and Emergency... Management Assistance Grant; 97.048, Disaster Housing Assistance to Individuals and Households In Presidentially Declared Disaster Areas; 97.049, Presidentially Declared Disaster Assistance--Disaster Housing...

NATO Human Resources (Manpower) Management (Gestion des ressources humaines (effectifs) de l’OTAN)

DTIC Science & Technology

2012-02-01

performances , la gestion des récompenses et du salaire, et la motivation du personnel. En conséquence, il faut que la gestion des ressources humaines...importance au fil du temps. Les ressources humaines, chargées à l’origine de l’embauche, du licenciement, de la paie et de la gestion des ...les effets des systèmes d’évaluation des performances ;

Determination dans les Installations au Sol des Parametres Aerodynamiques de Stabilite des Aeronefs (Determination in Ground Facilities of Aerodynamic Stability Parameters of Aircraft),

DTIC Science & Technology

1979-06-01

7 INTRODUCTION ...................................................................................... 12 CHAPITRE I : ELEMENTS DE DYNAMIQUE...daone Ie texts. 12 INTRODUCTION La ddtermination des ddrivdes adrodynamiques de stabilitd, en soufflerie et au tunnel de tir, aur des maquettes...ddtection des forces eat effectuds de fegon classiqus depuis plus de vingt ana par des barreaux d’acier dquipds de jauges de contrainte, gdndralament en

Electronic Messaging for the 90s (Les Messageries Electroniques des Annees 90)

DTIC Science & Technology

1993-05-01

des autres unitds (un programme peut par exemple inclure un algorithme de 2. L CICULAIONDE ’INFRMAION recherche dans des donn~es...dit quc le rdseau, en particulier le r.dseau distant, cette coopdration homme /macbine. aifre des performances bien infirieures A celles des ordinateurs...dans ce sens, entre constructeurs d’ordinateurs, des opdrations traitementltransport. constructeurs didquipements de t~ l ~communications et exploitants de

Using the verona coding definitions of emotional sequences (VR-CoDES) and health provider responses (VR-CoDES-P) in the dental context.

PubMed

Wright, Alice; Humphris, Gerry; Wanyonyi, Kristina L; Freeman, Ruth

2012-10-01

To show if cues, concerns and provider responses (defined in VR-CoDES and VR-CoDES-P manuals) are present, can be reliably coded and require additional advice for adoption in a dental context. Thirteen patients in a dental practice setting were videoed with either their dentist or hygienist and dental nurse present in routine treatment sessions. All utterances were coded using the Verona systems: VR-CoDES and the VR-CoDES-P. Rates of cue, concerns and provider responses described and reliability tested. The VR-CoDES and VR-CoDES-P were successfully applied in the dental context. The intra-rater ICCs for the detection of cues and concerns and provider response were acceptable and above 0.75. A similar satisfactory result was found for the inter-rater reliability. The VR-CoDES and the VR-CoDES-P are applicable in the dental setting with minor supporting guidelines and show evidence of reliable coding. The VR-CoDES and the VR-CoDES-P may be helpful tools for analysing patient cues and concerns and the dental professionals' responses in the dental context. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

Etude de pratiques d'enseignement relatives a la modelisation en sciences et technologies avec des enseignants du secondaire

NASA Astrophysics Data System (ADS)

Aurousseau, Emmanuelle

Les modeles sont des outils amplement utilises en sciences et technologies (S&T) afin de representer et d’expliquer un phenomene difficilement accessible, voire abstrait. La demarche de modelisation est presentee de maniere explicite dans le programme de formation de l’ecole quebecoise (PFEQ), notamment au 2eme cycle du secondaire (Quebec. Ministere de l'Education du Loisir et du Sport, 2007a). Elle fait ainsi partie des sept demarches auxquelles eleves et enseignants sont censes recourir. Cependant, de nombreuses recherches mettent en avant la difficulte des enseignants a structurer leurs pratiques d’enseignement autour des modeles et de la demarche de modelisation qui sont pourtant reconnus comme indispensables. En effet, les modeles favorisent la conciliation des champs concrets et abstraits entre lesquels le scientifique, meme en herbe, effectue des allers-retours afin de concilier le champ experimental de reference qu’il manipule et observe au champ theorique relie qu’il construit. L’objectif de cette recherche est donc de comprendre comment les modeles et la demarche de modelisation contribuent a faciliter l’articulation du concret et de l’abstrait dans l’enseignement des sciences et des technologies (S&T) au 2eme cycle du secondaire. Pour repondre a cette question, nous avons travaille avec les enseignants dans une perspective collaborative lors de groupes focalises et d’observation en classe. Ces dispositifs ont permis d’examiner les pratiques d’enseignement que quatre enseignants mettent en oeuvre en utilisant des modeles et des demarches de modelisation. L’analyse des pratiques d’enseignement et des ajustements que les enseignants envisagent dans leur pratique nous permet de degager des connaissances a la fois pour la recherche et pour la pratique des enseignants, au regard de l’utilisation des modeles et de la demarche de modelisation en S&T au secondaire.

Effets des electrons secondaires sur l'ADN

NASA Astrophysics Data System (ADS)

Boudaiffa, Badia

Les interactions des electrons de basse energie (EBE) representent un element important en sciences des radiations, particulierement, les sequences se produisant immediatement apres l'interaction de la radiation ionisante avec le milieu biologique. Il est bien connu que lorsque ces radiations deposent leur energie dans la cellule, elles produisent un grand nombre d'electrons secondaires (4 x 104/MeV), qui sont crees le long de la trace avec des energies cinetiques initiales bien inferieures a 20 eV. Cependant, il n'y a jamais eu de mesures directes demontrant l'interaction de ces electrons de tres basse energie avec l'ADN, du principalement aux difficultes experimentales imposees par la complexite du milieu biologique. Dans notre laboratoire, les dernieres annees ont ete consacrees a l'etude des phenomenes fondamentaux induits par impact des EBE sur differentes molecules simples (e.g., N2, CO, O2, H2O, NO, C2H 4, C6H6, C2H12) et quelques molecules complexes dans leur phase solide. D'autres travaux effectues recemment sur des bases de l'ADN et des oligonucleotides ont montre que les EBE produisent des bris moleculaires sur les biomolecules. Ces travaux nous ont permis d'elaborer des techniques pour mettre en evidence et comprendre les interactions fondamentales des EBE avec des molecules d'interet biologique, afin d'atteindre notre objectif majeur d'etudier l'effet direct de ces particules sur la molecule d'ADN. Les techniques de sciences des surfaces developpees et utilisees dans les etudes precitees peuvent etre etendues et combinees avec des methodes classiques de biologie pour etudier les dommages de l'ADN induits par l'impact des EBE. Nos experiences ont montre l'efficacite des electrons de 3--20 eV a induire des coupures simple et double brins dans l'ADN. Pour des energies inferieures a 15 eV, ces coupures sont induites par la localisation temporaire d'un electron sur une unite moleculaire de l'ADN, ce qui engendre la formation d'un ion negatif transitoire dans un etat electronique dissociatif, cette localisation est suivie d'une fragmentation. A plus haute energie, la dissociation dipolaire (i.e., la formation simultanee d'un ion positif et negatif) et l'ionisation jouent un role important dans le dommage de l'ADN. L'ensemble de nos resultats permet d'expliquer les mecanismes de degradation de l'ADN par les EBE et d'obtenir des sections efficaces effectives des differents types de dommages.

PubMed

Belaid, Loubna; Cloos, Patrick; Ridde, Valéry

2017-04-20

Cette étude vise à décrire la mobilisation des représentations ethnoculturelles par des agents et des gestionnaires de santé pour expliquer l'échec partiel d'une politique de santé maternelle et discuter des conséquences potentielles de ces représentations sur l'accès aux soins de santé des populations.MÉTHODES : Il s'agit d'une recherche qualitative de type socio-anthropologique mobilisant des entretiens approfondis, des discussions informelles, des observations non participantes menées dans les centres de santé et une analyse documentaire. Les entretiens ont été menés auprès de 16 agents de santé et de 10 gestionnaires. Les entretiens ont été enregistrés sous support numérique et transcrits. L'étude s'est déroulée dans le district sanitaire de Djibo au Burkina Faso.RÉSULTATS : L'identification ethnique, les coutumes relatives à l'accouchement (pudeur, discrétion, présence féminine), le statut social des femmes (le faible pouvoir décisionnel), le nomadisme et l'organisation sociale des populations et leurs résistances au changement sont érigés comme des obstacles « culturels » à la politique de santé. L'usage largement répandu de ces représentations par les agents et les gestionnaires de santé contribue à réprimander les populations et à masquer les facteurs structurels qui ont pourtant une influence plus importante sur l'utilisation des services de santé maternelle. Cette recherche met en lumière le danger de l'usage excessif des représentations ethnoculturelles teintées de culturalisme dans les pratiques et les politiques de santé publique en véhiculant des stéréotypes à l'égard de certains groupes de population. Pour comprendre le succès ou l'échec des politiques sanitaires, il demeure important de considérer la qualité du contact avec le système de santé, les facteurs structurels notamment les capacités des ménages à faire face aux dépenses des soins de santé et des distances entre les villages et les centres de santé. Ces éléments permettraient de mieux comprendre les disparités constatées à l'égard des indicateurs d'utilisation des services de santé.

Workshop held on natural disasters

NASA Astrophysics Data System (ADS)

Rundle, John; Klein, W.; Turcotte, D.

Natural hazards such as earthquakes and floods are a menace to the population worldwide. The United Nations focused attention on this global problem by declaring the 1990s the Decade of Natural Hazard Reduction. In addition to threatening human life, natural hazards can cause severe economic hardship locally and, in an ever more complex and interactive world economy, dislocations that are felt in areas far beyond the site of a disaster.Recent catastrophic earthquakes, hurricanes, floods, and fires have called into question the ability of private insurers to cover economic losses. Unlimited liability is a necessity for confidence in insurance coverage, but these events have stretched the resources of even the largest insurers.

Tattoo as art, the drivers behind the fascination and the decision to become tattooed.

PubMed

Kierstein, Liz; Kjelskau, Kari C

2015-01-01

For many people, getting a tattoo is like purchasing art, and many professional and famous tattooists are artists who are acknowledged by colleagues and authorities. The history of tattooing goes back for thousands of years, and the reasons for getting tattooed are many. These permanent markings are always personal, they can be plain or elaborate, and they serve as amulets, healing and status symbols, declarations of love, signs of religion, adornments and even forms of punishment. Drivers behind the fascination of acquiring a tattoo may fall into four main groups, namely healing, affiliation, art and fashion. © 2015 S. Karger AG, Basel.

La projection par plasma : une revue

NASA Astrophysics Data System (ADS)

Fauchais, P.; Grimaud, A.; Vardelle, A.; Vardelle, M.

The quality of a plasma sprayed coating depends on numerous parameters that start to be understood due to the recent progresses in modelling and measurement techniques for plasma jets, momentum, heat and mass transfers between plasma and particles, the way the particules splat and cool down upon impact on the substrate or the previously deposited layers. In this paper, first are recalled the used measurement techniques and their limitations both for plasma jets and particles in flight. Then are underlined the importance of the different phenomena envolved in the transfers between plasma and particles such as steep temperature and chemical species density gradients around the particles, heat propagation phenomenon especially for ceramic particles and the connected evaporation effect, rarefaction effect which occurs even at atmospheric pressure. The problems related to the size and injection velocity distributions which determine the trajectory distributions and the heat treatments undergone by the particles are treated. The study of plasma generation shows on one hand for d.c. arc plasma torches the drastic influence on the plasma jets lengths and diameters of the gas injection chamber design, the gas nature, the design of the arc chamber and nozzle, the surrounding atmosphere (especially air pumping which cools down very fast the plasma) and on the other hand for RF plasmas the importance of the particle injection design to avoid the coupling between the RF discharge and the carrier gas with the particles. All these points are illustrated with examples of coatings of alumina, zirconia carbide and nickel particles. The way the particles splat is then studied with the chemical reactions in flight, the fast quenching of the particles and the resulting cristalline structures, the coating adhesion and also the residual stesses and their control through that of the temperature gradients into the coatings during spraying. At last a few actual and potential applications are presented in the fields of aeronautics and mechanics. La qualité d'un dépôt projete par plasma dépend de nombreux paramètres que l'on commence à mieux appréhender du fait des progrès de la modélisation et de la métrologie tant des écoulements plasmas que des transferts plasma-particules ou que des conditions d'écrasement et de refroidissement des particules lors de leur impact sur le substrat ou les couches déjà déposées. Les techniques de mesure utilisdes et leurs limitations sont d'abord rappelées tant pour les jets de plasma que pour les particules en vol et l'importance des différents phénomènes intervenant dans les transferts plasma-particules est soulignée : gradients de température et de concentration d'espèces chimiques très élevés autour des particules, effets de propagation de la chaleur, notamment pour les particules céramiques, effet d'évaporation, effet de raréfaction sensible dès la pression atmosphérique. Les problèmes de distribution de taille et de vitesse d'injection des particules sont également abordés car ils conditionnent les distributions de trajectoires et donc le traitement des particules dans le jet de plasma. La génération du plasma montre d'une part 1'influence considérable de l'injection du gaz, de sa nature, du dessin de la chambre d'arc et de la tuyère ainsi que du pompage de l'air ambiant sur la longueur des jets de plasma d'arc et d'autre part les problèmes d'injection pour éviter le couplage avec la décharge dans les jets de plasmas R.E Tout ceci est illustré avec des exemples de dépôt d'alumine, de zircone, de cermet carbure et de nickel. L'écrasement des particules est ensuite abordé avec les problèmes de réactions chimiques, de trempe ultra-rapide et donc de structure cristalline des dépôts, d'adhdsion mais aussi de containtes résiduelles et de leur contrôle via les gradients de température dans les dépôts pendant le tir. Enfin quelques applications actuelles sont présentées notamment pour l'aéronautique et la mécanique.

37 CFR 2.167 - Affidavit or declaration under section 15.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false Affidavit or declaration under section 15. 2.167 Section 2.167 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND TRADEMARK OFFICE, DEPARTMENT OF COMMERCE RULES OF PRACTICE IN TRADEMARK CASES Affidavit Or Declaration Under...

76 FR 61130 - New York Disaster Number NY-00110

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-03

... SMALL BUSINESS ADMINISTRATION [Disaster Declaration 12824 and 12825] New York Disaster Number NY... the Presidential declaration of a major disaster for the State of New York (FEMA-4031-DR), dated 09/13... major disaster declaration for the State of New York, dated 09/13/2011 is hereby amended to establish...

76 FR 56852 - New York Disaster Number NY-00108

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-14

... SMALL BUSINESS ADMINISTRATION [Disaster Declaration 12776 and 12777] New York Disaster Number NY... the Presidential declaration of a major disaster for the State of New York (FEMA-4020-DR), dated 08/31... major disaster declaration for the State of New York, dated 08/31/2011 is hereby amended to establish...

Accounting for Change in Declarative Memory: A Cognitive Neuroscience Perspective

ERIC Educational Resources Information Center

Richmond, Jenny; Nelson, Charles A.

2007-01-01

The medial temporal lobe memory system matures relatively early and supports rudimentary declarative memory in young infants. There is considerable development, however, in the memory processes that underlie declarative memory performance during infancy. Here we consider age-related changes in encoding, retention, and retrieval in the context of…

76 FR 56858 - Puerto Rico Disaster Number PR-00014

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-14

... SMALL BUSINESS ADMINISTRATION [Disaster Declaration 12768 and 12769] Puerto Rico Disaster Number... amendment of the Presidential declaration of a major disaster for the Commonwealth of Puerto Rico (FEMA-4017... disaster declaration for the Commonwealth of PUERTO RICO, dated 08/27/2011 is hereby amended to include the...

76 FR 62133 - Puerto Rico Disaster Number PR-00014

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-06

... SMALL BUSINESS ADMINISTRATION [Disaster Declaration 12768 and 12769] Puerto Rico Disaster Number... amendment of the Presidential declaration of a major disaster for the Commonwealth of Puerto Rico (FEMA-4017... disaster declaration for the Commonwealth of Puerto Rico, dated 08/27/2011 is hereby amended to include the...

76 FR 74837 - Puerto Rico Disaster Number PR-00014

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-01

... SMALL BUSINESS ADMINISTRATION [Disaster Declaration 12768 and 12769] Puerto Rico Disaster Number... amendment of the Presidential declaration of a major disaster for the State of Puerto Rico (FEMA-4017-DR... disaster declaration for the State of Puerto Rico, dated 08/27/2011 is hereby amended to extend the...

76 FR 71248 - Animal Food Labeling; Declaration of Certifiable Color Additives

Federal Register 2010, 2011, 2012, 2013, 2014

2011-11-17

.... FDA-2009-N-0025] Animal Food Labeling; Declaration of Certifiable Color Additives AGENCY: Food and... amending its regulations regarding the declaration of certified color additives on the labels of animal... common or usual names of all color additives required to be certified by FDA. An additional purpose of...

19 CFR 148.111 - Written declaration for unaccompanied articles.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 19 Customs Duties 2 2011-04-01 2011-04-01 false Written declaration for unaccompanied articles... of the United States § 148.111 Written declaration for unaccompanied articles. The baggage... covers articles which do not accompany him and: (a) The articles are entitled to free entry under the $1...

19 CFR 148.111 - Written declaration for unaccompanied articles.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 19 Customs Duties 2 2013-04-01 2013-04-01 false Written declaration for unaccompanied articles... of the United States § 148.111 Written declaration for unaccompanied articles. The baggage... covers articles which do not accompany him and: (a) The articles are entitled to free entry under the $1...

76 FR 27079 - Agency Information Collection Activities: Declaration of Unaccompanied Articles

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-10

... Activities: Declaration of Unaccompanied Articles AGENCY: U.S. Customs and Border Protection, Department of...: Declaration of Unaccompanied Articles (CBP Form 255). This is a proposed extension of an information... Articles. OMB Number: 1651-0030. Form Number: CBP Form 255. Abstract: CBP Form 255 is completed by...

19 CFR 148.111 - Written declaration for unaccompanied articles.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 19 Customs Duties 2 2012-04-01 2012-04-01 false Written declaration for unaccompanied articles... of the United States § 148.111 Written declaration for unaccompanied articles. The baggage... covers articles which do not accompany him and: (a) The articles are entitled to free entry under the $1...

19 CFR 148.111 - Written declaration for unaccompanied articles.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 19 Customs Duties 2 2010-04-01 2010-04-01 false Written declaration for unaccompanied articles... of the United States § 148.111 Written declaration for unaccompanied articles. The baggage... covers articles which do not accompany him and: (a) The articles are entitled to free entry under the $1...

78 FR 26679 - Massachusetts Disaster #MA-00055 Declaration of Economic Injury

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-07

... Declaration of Economic Injury AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This is a notice of an Economic Injury Disaster Loan (EIDL) declaration for the Commonwealth of Massachusetts..., applications for economic injury disaster loans may be filed at the address listed above or other locally...

77 FR 76585 - Oregon Disaster #OR-00045 Declaration of Economic Injury

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-28

... Economic Injury AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This is a notice of an Economic Injury Disaster Loan (EIDL) declaration for the State of Oregon, dated 12/12/2012. Incident: Pole... result of the Administrator's EIDL declaration, applications for economic injury disaster loans may be...

76 FR 23639 - Oklahoma Disaster #OK-00046 Declaration of Economic Injury

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-27

... of Economic Injury AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This is a notice of an Economic Injury Disaster Loan (EIDL) declaration for the State of Oklahoma, dated 04/19/2011... hereby given that as a result of the Administrator's EIDL declaration, applications for economic injury...

78 FR 49318 - Colorado Disaster # CO-00055 Declaration of Economic Injury

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-13

... of Economic Injury AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This is a notice of an Economic Injury Disaster Loan (EIDL) declaration for the State of Colorado, dated 08/06/2013... given that as a result of the Administrator's EIDL declaration, applications for economic injury...

76 FR 27738 - Connecticut Disaster #CT-00021 Declaration of Economic Injury

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-12

... of Economic Injury AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This is a notice of an Economic Injury Disaster Loan (EIDL) declaration for the State of Connecticut, dated 05/04... hereby given that as a result of the Administrator's EIDL declaration, applications for economic injury...

78 FR 66983 - Massachusetts Disaster #MA-00056 Declaration of Economic Injury

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-07

... Declaration of Economic Injury AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This is a notice of an Economic Injury Disaster Loan (EIDL) declaration for the Commonwealth of Massachusetts..., applications for economic injury disaster loans may be filed at the address listed above or other locally...

78 FR 56979 - Oregon Disaster #OR-00051 Declaration of Economic Injury

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-16

... Economic Injury AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This is a notice of an Economic Injury Disaster Loan (EIDL) declaration for the State of Oregon, dated 09/06/2013. Incident... result of the Administrator's EIDL declaration, applications for economic injury disaster loans may be...

78 FR 44186 - Colorado Disaster # CO-00058 Declaration of Economic Injury

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-23

... of Economic Injury AGENCY: U.S. Small Business Administration. ACTION: Notice SUMMARY: This is a notice of an Economic Injury Disaster Loan (EIDL) declaration for the State of Colorado, dated 07/15/2013... given that as a result of the Administrator's EIDL declaration, applications for economic injury...

29 CFR 18.803 - Hearsay exceptions; availability of declarant immaterial.

Code of Federal Regulations, 2010 CFR

2010-07-01

..., or immediately thereafter. (2) Excited utterance. A statement relating to a startling event or condition made while the declarant was under the stress of excitement caused by the event or condition. (3... remembered or believed unless it relates to the execution, revocation, identification, or terms of declarant...

37 CFR 1.68 - Declaration in lieu of oath.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false Declaration in lieu of oath..., the declarant is on the same document, warned that willful false statements and the like are... information and belief are believed to be true. [49 FR 48452, Dec. 12, 1984] ...

37 CFR 1.68 - Declaration in lieu of oath.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 37 Patents, Trademarks, and Copyrights 1 2014-07-01 2014-07-01 false Declaration in lieu of oath..., the declarant is on the same document, warned that willful false statements and the like are... information and belief are believed to be true. [49 FR 48452, Dec. 12, 1984] ...

42 CFR 431.980 - Eligibility review procedures.

Code of Federal Regulations, 2010 CFR

2010-10-01

... plan during the month under review. (vi) Elements of eligibility in which State policy allows for self-declaration or self-certification are considered to be verified with a self-declaration or self-certification statement. The self-declaration or self-certification must be— (A) Present in the record; (B) Not outdated...

7 CFR 786.100 - Applicability.

Code of Federal Regulations, 2011 CFR

2011-01-01

... production losses in eligible counties as a result of a natural disaster declared during the period between... of January 2, 2005, through December 30, 2007, in a county declared a natural disaster by the... to a county that is directly eligible by way of a natural disaster declaration are also eligible...

7 CFR 786.100 - Applicability.

Code of Federal Regulations, 2013 CFR

2013-01-01

... production losses in eligible counties as a result of a natural disaster declared during the period between... of January 2, 2005, through December 30, 2007, in a county declared a natural disaster by the... to a county that is directly eligible by way of a natural disaster declaration are also eligible...

7 CFR 786.100 - Applicability.

Code of Federal Regulations, 2010 CFR

2010-01-01

... production losses in eligible counties as a result of a natural disaster declared during the period between... of January 2, 2005, through December 30, 2007, in a county declared a natural disaster by the... to a county that is directly eligible by way of a natural disaster declaration are also eligible...

7 CFR 786.100 - Applicability.

Code of Federal Regulations, 2012 CFR

2012-01-01

... production losses in eligible counties as a result of a natural disaster declared during the period between... of January 2, 2005, through December 30, 2007, in a county declared a natural disaster by the... to a county that is directly eligible by way of a natural disaster declaration are also eligible...

7 CFR 786.100 - Applicability.

Code of Federal Regulations, 2014 CFR

2014-01-01

... production losses in eligible counties as a result of a natural disaster declared during the period between... of January 2, 2005, through December 30, 2007, in a county declared a natural disaster by the... to a county that is directly eligible by way of a natural disaster declaration are also eligible...

75 FR 44994 - Florida Disaster # FL-00056 Declaration of Economic Injury

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-30

... of Economic Injury AGENCY: U.S. Small Business Administration. ACTION: Amendment 1. SUMMARY: This is an amendment of an Economic Injury Disaster Loan (EIDL) declaration for the State of FLORIDA, dated.... SUPPLEMENTARY INFORMATION: The notice of an Economic Injury declaration for the State of Florida dated 05/13...

9 CFR 93.305 - Declaration and other documents for horses.

Code of Federal Regulations, 2010 CFR

2010-01-01

... horses. 93.305 Section 93.305 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE...; REQUIREMENTS FOR MEANS OF CONVEYANCE AND SHIPPING CONTAINERS Horses § 93.305 Declaration and other documents for horses. (a) The certificates, declarations, and affidavits required by the regulations in this...

21 CFR 1313.23 - Distribution of export declaration.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 21 Food and Drugs 9 2011-04-01 2011-04-01 false Distribution of export declaration. 1313.23 Section 1313.23 Food and Drugs DRUG ENFORCEMENT ADMINISTRATION, DEPARTMENT OF JUSTICE IMPORTATION AND...; declaration forms for list II chemical must be retained for two years. (b) Copy 2 is the Drug Enforcement...

44 CFR 204.24 - Determination on request for a fire management assistance declaration.

Code of Federal Regulations, 2014 CFR

2014-10-01

... ASSISTANCE GRANT PROGRAM Declaration Process § 204.24 Determination on request for a fire management... 44 Emergency Management and Assistance 1 2014-10-01 2014-10-01 false Determination on request for a fire management assistance declaration. 204.24 Section 204.24 Emergency Management and Assistance...

44 CFR 204.24 - Determination on request for a fire management assistance declaration.

Code of Federal Regulations, 2012 CFR

2012-10-01

... ASSISTANCE GRANT PROGRAM Declaration Process § 204.24 Determination on request for a fire management... 44 Emergency Management and Assistance 1 2012-10-01 2011-10-01 true Determination on request for a fire management assistance declaration. 204.24 Section 204.24 Emergency Management and Assistance...

44 CFR 204.24 - Determination on request for a fire management assistance declaration.

Code of Federal Regulations, 2013 CFR

2013-10-01

... ASSISTANCE GRANT PROGRAM Declaration Process § 204.24 Determination on request for a fire management... 44 Emergency Management and Assistance 1 2013-10-01 2013-10-01 false Determination on request for a fire management assistance declaration. 204.24 Section 204.24 Emergency Management and Assistance...

44 CFR 204.24 - Determination on request for a fire management assistance declaration.

Code of Federal Regulations, 2011 CFR

2011-10-01

... ASSISTANCE GRANT PROGRAM Declaration Process § 204.24 Determination on request for a fire management... 44 Emergency Management and Assistance 1 2011-10-01 2011-10-01 false Determination on request for a fire management assistance declaration. 204.24 Section 204.24 Emergency Management and Assistance...

77 FR 52379 - Disaster Declaration #13239 and #13240; OHIO Disaster # H-00030

Federal Register 2010, 2011, 2012, 2013, 2014

2012-08-29

... SMALL BUSINESS ADMINISTRATION Disaster Declaration 13239 and 13240; OHIO Disaster H-00030 AGENCY... declaration of a major disaster for Public Assistance Only for the State of OHIO (FEMA-4077- DR), dated 08/20..., Perry, Pickaway, Pike, Putnam, Shelby, Van Wert, Washington. The Interest Rates are: Percent For...

19 CFR 148.16 - Amendment of declaration.

Code of Federal Regulations, 2010 CFR

2010-04-01

.... (a) Before examination. A passenger shall be permitted to add an article to his declaration if, before examination of his baggage has begun, the fact that the article has not been declared is brought to the attention of the examining officer by the passenger. (b) After examination is begun. A...

76 FR 58330 - New Hampshire Disaster Number NH-00019

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-20

... SMALL BUSINESS ADMINISTRATION [Disaster Declaration 12811 and 12812] New Hampshire Disaster Number... amendment of the Presidential declaration of a major disaster for the State of New Hampshire (FEMA--4026--DR... major disaster declaration for the State of New Hampshire, dated 09/07/2011 is hereby amended to...

77 FR 35699 - Proposed Information Collection; Request for Public Comment: Addendum to Declaration for Federal...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-14

...; Request for Public Comment: Addendum to Declaration for Federal Employment, Child Care and Indian Child...) for review. Proposed Collection: Title: Addendum to Declaration for Federal Employment, Child Care and Indian Child Care Worker Positions (OMB No. 0917-0028). Type of Information Collection Request: Extension...

15 CFR 711.2 - Who submits declarations, reports, and advance notifications.

Code of Federal Regulations, 2012 CFR

2012-01-01

... REQUIREMENTS, AND THE ELECTRONIC FILING OF DECLARATIONS AND REPORTS § 711.2 Who submits declarations, reports, and advance notifications. The owner, operator, or senior management official of a facility subject to... subchapter) is responsible for the submission of all required documents in accordance with all applicable...

15 CFR 711.2 - Who submits declarations, reports, and advance notifications.

Code of Federal Regulations, 2011 CFR

2011-01-01

... REQUIREMENTS, AND THE ELECTRONIC FILING OF DECLARATIONS AND REPORTS § 711.2 Who submits declarations, reports, and advance notifications. The owner, operator, or senior management official of a facility subject to... subchapter) is responsible for the submission of all required documents in accordance with all applicable...

15 CFR 711.2 - Who submits declarations, reports, and advance notifications.

Code of Federal Regulations, 2014 CFR

2014-01-01

... REQUIREMENTS, AND THE ELECTRONIC FILING OF DECLARATIONS AND REPORTS § 711.2 Who submits declarations, reports, and advance notifications. The owner, operator, or senior management official of a facility subject to... subchapter) is responsible for the submission of all required documents in accordance with all applicable...

15 CFR 711.2 - Who submits declarations, reports, and advance notifications.

Code of Federal Regulations, 2010 CFR

2010-01-01

... REQUIREMENTS, AND THE ELECTRONIC FILING OF DECLARATIONS AND REPORTS § 711.2 Who submits declarations, reports, and advance notifications. The owner, operator, or senior management official of a facility subject to... subchapter) is responsible for the submission of all required documents in accordance with all applicable...

15 CFR 711.2 - Who submits declarations, reports, and advance notifications.

Code of Federal Regulations, 2013 CFR

2013-01-01

... REQUIREMENTS, AND THE ELECTRONIC FILING OF DECLARATIONS AND REPORTS § 711.2 Who submits declarations, reports, and advance notifications. The owner, operator, or senior management official of a facility subject to... subchapter) is responsible for the submission of all required documents in accordance with all applicable...

10 CFR 26.209 - Self-declarations.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 1 2013-01-01 2013-01-01 false Self-declarations. 26.209 Section 26.209 Energy NUCLEAR REGULATORY COMMISSION FITNESS FOR DUTY PROGRAMS Managing Fatigue § 26.209 Self-declarations. (a) If an individual is performing, or being assessed for, work under a waiver of one or more of the requirements...

10 CFR 26.209 - Self-declarations.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 1 2014-01-01 2014-01-01 false Self-declarations. 26.209 Section 26.209 Energy NUCLEAR REGULATORY COMMISSION FITNESS FOR DUTY PROGRAMS Managing Fatigue § 26.209 Self-declarations. (a) If an individual is performing, or being assessed for, work under a waiver of one or more of the requirements...

10 CFR 26.209 - Self-declarations.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 10 Energy 1 2012-01-01 2012-01-01 false Self-declarations. 26.209 Section 26.209 Energy NUCLEAR REGULATORY COMMISSION FITNESS FOR DUTY PROGRAMS Managing Fatigue § 26.209 Self-declarations. (a) If an individual is performing, or being assessed for, work under a waiver of one or more of the requirements...

15 CFR 714.6 - Deadlines for submission of Schedule 3 declarations, reports, and amendments.

Code of Federal Regulations, 2012 CFR

2012-01-01

... report on exports and imports of Schedule 3 chemicals from plant sites, trading companies, and other... chemicals, by a declared plant site during the previous calendar year); (d) Annual declaration on... Commerce and Foreign Trade (Continued) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE CHEMICAL...

15 CFR 714.6 - Deadlines for submission of Schedule 3 declarations, reports, and amendments.

Code of Federal Regulations, 2013 CFR

2013-01-01

... report on exports and imports of Schedule 3 chemicals from plant sites, trading companies, and other... chemicals, by a declared plant site during the previous calendar year); (d) Annual declaration on... Commerce and Foreign Trade (Continued) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE CHEMICAL...

15 CFR 714.6 - Deadlines for submission of Schedule 3 declarations, reports, and amendments.

Code of Federal Regulations, 2014 CFR

2014-01-01

... report on exports and imports of Schedule 3 chemicals from plant sites, trading companies, and other... chemicals, by a declared plant site during the previous calendar year); (d) Annual declaration on... Commerce and Foreign Trade (Continued) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE CHEMICAL...

9 CFR 93.506 - Declaration and other documents for swine.

Code of Federal Regulations, 2013 CFR

2013-01-01

... swine. 93.506 Section 93.506 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE...; REQUIREMENTS FOR MEANS OF CONVEYANCE AND SHIPPING CONTAINERS Swine § 93.506 Declaration and other documents for swine. (a) The certificates, declarations, and affidavits required by the regulations in this part shall...

9 CFR 93.506 - Declaration and other documents for swine.

Code of Federal Regulations, 2014 CFR

2014-01-01

... swine. 93.506 Section 93.506 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE...; REQUIREMENTS FOR MEANS OF CONVEYANCE AND SHIPPING CONTAINERS Swine § 93.506 Declaration and other documents for swine. (a) The certificates, declarations, and affidavits required by the regulations in this part shall...

9 CFR 93.506 - Declaration and other documents for swine.

Code of Federal Regulations, 2010 CFR

2010-01-01

... swine. 93.506 Section 93.506 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE...; REQUIREMENTS FOR MEANS OF CONVEYANCE AND SHIPPING CONTAINERS Swine § 93.506 Declaration and other documents for swine. (a) The certificates, declarations, and affidavits required by the regulations in this part shall...

9 CFR 93.506 - Declaration and other documents for swine.

Code of Federal Regulations, 2012 CFR

2012-01-01

... swine. 93.506 Section 93.506 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE...; REQUIREMENTS FOR MEANS OF CONVEYANCE AND SHIPPING CONTAINERS Swine § 93.506 Declaration and other documents for swine. (a) The certificates, declarations, and affidavits required by the regulations in this part shall...

10 CFR 26.209 - Self-declarations.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 1 2010-01-01 2010-01-01 false Self-declarations. 26.209 Section 26.209 Energy NUCLEAR REGULATORY COMMISSION FITNESS FOR DUTY PROGRAMS Managing Fatigue § 26.209 Self-declarations. (a) If an individual is performing, or being assessed for, work under a waiver of the requirements contained in § 26...

10 CFR 26.209 - Self-declarations.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 1 2011-01-01 2011-01-01 false Self-declarations. 26.209 Section 26.209 Energy NUCLEAR REGULATORY COMMISSION FITNESS FOR DUTY PROGRAMS Managing Fatigue § 26.209 Self-declarations. (a) If an individual is performing, or being assessed for, work under a waiver of the requirements contained in § 26...

77 FR 2306 - Agency Information Collection Activities: Submission for OMB Review; Comment Request, Federal...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-01-17

... Request, Federal Hotel and Motel Fire Safety Declaration Form AGENCY: Federal Emergency Management Agency... Title: Federal Hotel and Motel Fire Safety Declaration Form. Type of information collection: Extension... Numbers: FEMA Form 516-0-1, Federal Hotel and Motel Fire Safety Declaration Form. Abstract: FEMA collects...

21 CFR 801.62 - Declaration of net quantity of contents.

Code of Federal Regulations, 2011 CFR

2011-04-01

... paragraph (p) of this section. (c) The declaration may contain common or decimal fractions. A common... there exists a firmly established, general consumer usage and trade custom of employing different common fractions in the net quantity declaration of a particular commodity, they may be employed. A common fraction...

21 CFR 201.62 - Declaration of net quantity of contents.

Code of Federal Regulations, 2011 CFR

2011-04-01

... this section. (c) The declaration may contain common or decimal fractions. A common fraction shall be... firmly established, general consumer usage and trade custom of employing different common fractions in the net quantity declaration of a particular commodity, they may be employed. A common fraction shall...

21 CFR 201.62 - Declaration of net quantity of contents.

Code of Federal Regulations, 2010 CFR

2010-04-01

... this section. (c) The declaration may contain common or decimal fractions. A common fraction shall be... firmly established, general consumer usage and trade custom of employing different common fractions in the net quantity declaration of a particular commodity, they may be employed. A common fraction shall...

21 CFR 701.13 - Declaration of net quantity of contents.

Code of Federal Regulations, 2011 CFR

2011-04-01

... will give such information. (d) The declaration may contain common or decimal fractions. A common... there exists a firmly established, general consumer usage and trade custom of employing different common fractions in the net quantity declaration of a particular commodity they may be employed. A common fraction...

44 CFR 204.23 - Processing a request for a fire management assistance declaration.

Code of Federal Regulations, 2010 CFR

2010-10-01

... management assistance declaration. The Principal Advisor may consult with State agencies, usually emergency... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Processing a request for a fire management assistance declaration. 204.23 Section 204.23 Emergency Management and Assistance...

75 FR 82241 - Technical Correction: Completion of Entry and Entry Summary-Declaration of Value

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-30

... Entry Summary-- Declaration of Value AGENCY: Customs and Border Protection, Department of Homeland... manner by which the declared transaction value on imported merchandise was determined. This requirement... whether the transaction value of imported merchandise is determined on the basis of the price paid by the...

The Universal Declaration of Human Rights - Only a Foundation.

ERIC Educational Resources Information Center

Reichert, Elisabeth

2002-01-01

Explains provisions contained within the Universal Declaration of Human Rights, tracing historical beginnings of human rights to 1945, detailing events after 1945 up to the adoption of the Universal Declaration of Human Rights by the United Nations, and explaining essential terminology used in describing human rights instruments that have been…

15 CFR 716.2 - Purposes and types of inspections of declared facilities.

Code of Federal Regulations, 2011 CFR

2011-01-01

... Foreign Trade (Continued) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE CHEMICAL WEAPONS... chemical, except for the declared Schedule 1 chemicals; (ii) The quantities of Schedule 1 chemicals...; and (iii) The Schedule 1 chemical is not diverted or used for purposes other than those declared. (2...

15 CFR 716.2 - Purposes and types of inspections of declared facilities.

Code of Federal Regulations, 2010 CFR

2010-01-01

... Foreign Trade (Continued) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE CHEMICAL WEAPONS... chemical, except for the declared Schedule 1 chemicals; (ii) The quantities of Schedule 1 chemicals...; and (iii) The Schedule 1 chemical is not diverted or used for purposes other than those declared. (2...

15 CFR 714.3 - Advance declaration requirements for additionally planned production of Schedule 3 chemicals.

Code of Federal Regulations, 2011 CFR

2011-01-01

... COMMERCE CHEMICAL WEAPONS CONVENTION REGULATIONS ACTIVITIES INVOLVING SCHEDULE 3 CHEMICALS § 714.3 Advance declaration requirements for additionally planned production of Schedule 3 chemicals. (a) Declaration... additionally planned production of Schedule 3 chemicals. 714.3 Section 714.3 Commerce and Foreign Trade...

[The Helsinki Declaration: relativism and vulnerability].

PubMed

Diniz, D; Corrêa, M

2001-01-01

The Helsinki Declaration is a crucial ethical landmark for clinical research involving human beings. Since the Declaration was issued, a series of revisions and modifications have been introduced into the original text, but they have not altered its humanist approach or its international force for regulating clinical research. A proposal for an extensive revision of the Declaration's underlying ethical principles has been debated for the past four years. If the proposal is approved, international clinical research involving human beings will be modified, further increasing the vulnerability of certain social groups. This article discusses the historical process involved in passing the Helsinki Declaration and the most recent debate on the new draft. The article analyzes the new text's social implications for underdeveloped countries, arguing for a political approach to the vulnerability concept.

The social and policy contexts of the New Brunswick Declaration on Research Ethics, Integrity, and Governance: a commentary.

PubMed

van den Hoonaard, Will C

2013-04-01

This paper explores the social and policy implications of the "New Brunswick Declaration on Research Ethics, Integrity, and Governance" developed at the Ethics Rupture Summit in Fredericton, N.B., Canada, October 2012. It discusses the Declaration and the Summit in relation to the usual criticism and analysis of research ethics regimes, and considers reasons why the immense prior literature has had little impact on regulatory bodies. Because the Declaration, like the Illinois White Paper, has quickly achieved considerable attention relative to most other such documents, and because much further deliberation has evolved since the Summit, we offer here a commentary on each of the eight principles contained in the Declaration in the hope of further stimulating discussion and consolidating the progress that now seems underway.

"Voici des fruits, des fleurs, des feuilles et des branches" et pourquoi pas des legumes? ("Here are Fruits, Flowers, Leaves, and Branches" and Why Not Vegetables?).

ERIC Educational Resources Information Center

van Zundert, Danielle

1986-01-01

Describes an experiment in teaching language to young children through nature study. Activities are outlined, including the linguistic, cognitive, and cultural objectives for each. Brief illustrated descriptions are also given. (MSE)

US Army Morale, Welfare and Recreation (MWR) Programmes : Links to Readiness and Retention

DTIC Science & Technology

2011-01-01

la Direction des opérations, Bureau du sous-chef d’état-major pour la ... gestion des emprises et garnisons de l’US Army, Washington, DC. Il enseigne au Département de philosophie du Northern Virginia Community College...américaine à l’intention des personnels militaires et des familles, et des variables mesurant l’état de préparation des forces et la fidélisation de

Aircraft Disinsection: A Guide for Military and Civilian Air Carriers (Desinsectisation des aeronefs: Un guide a l’intention des responsables des transports aeriens civils et militaires)

DTIC Science & Technology

1996-04-01

regulations. - Ceratitis capitata (Mediterranean fruit fly). Quarantine regulations generally reduce - Rhagoletis pomonella (Apple maggot). the chances of a...d’insectes nuisibles dans un pays, en 6vitant des risques pour la sant6 des 6quipages, pour la s~curit6 de 1’a~ronef et pour l’industrie. Ce rapport examine 1...diffrrents officiels responsables de la r~glementation des insectes nuisibles introduits, de l’inscription des pesticides et de leur utilisation en

Contrôler la douleur et réduire l’usage abusif d’opioïdes

PubMed Central

Kotalik, Jaro

2012-01-01

Résumé Objectif Aider les médecins de famille à faire un juste équilibre sur le plan de l’éthique dans leurs pratiques de prescription d’opioïdes. Source des données Une recension des articles en anglais publiés entre 1985 et 2011 a été effectuée dans MEDLINE. La majorité des données probantes étaient de niveau III. Message principal Il est essentiel de suivre les guides de pratique clinique quand on prescrit des opioïdes, sauf s’il est démontré qu’une autre option est justifiée. De plus, quand on réfléchit à la pertinence de prescrire des opioïdes et aux nombreuses implications sur le plan de l’éthique, il est utile de fonder sa décision sur l’application des principes éthiques de la bienfaisance, de la non-malfaisance, du respect de l’autonomie et de la justice. En outre, il est essentiel de se tenir au fait des changements dans les lois et la règlementation, ainsi qu’à propos des registres électroniques provinciaux des ordonnances d’opioïdes. Conclusion Les médecins doivent s’assurer que la douleur de leurs patients est bien évaluée et prise en charge. Le contrôle optimal de la douleur peut exiger la prescription d’opioïdes. Cependant, l’obligation de soulager la douleur doit être exercée en juste équilibre avec l’acquittement de la responsabilité tout aussi importante de ne pas exposer les patients au risque de dépendance et de ne pas créer de possibilités de détournement de drogues, de trafic et de dépendance chez d’autres personnes. Les principes éthiques fondamentaux offrent un cadre de réflexion qui peut aider les médecins à prendre des décisions appropriées sur le plan de l’éthique au sujet de la prescription d’opioïdes.

Approche à l’endroit des blessures traumatiques à la main en soins primaires

PubMed Central

Cheung, Kevin; Hatchell, Alexandra; Thoma, Achilleas

2013-01-01

Résumé Objectif Passer en revue la prise en charge initiale des blessures traumatiques communes à la main que voient les médecins de soins primaires. Sources des données Nous avons examiné les données cliniques probantes et les ouvrages spécialisés récents cernés par des recherches dans la base de données électronique MEDLINE. Nous avons utilisé l’opinion d’experts pour compléter les recommandations dans les domaines où les données scientifiques étaient rares. Message principal Les médecins de soins primaires sont couramment appelés à prendre en charge des patients victimes de blessures traumatiques à la main. Dans le contexte d’un cas clinique, nous examinons l’évaluation, le diagnostic et la prise en charge initiale des traumatismes communs à la main. La présentation et la prise en charge des blessures au lit de l’ongle, des amputations de l’extrémité du doigt, des doigts en maillet, des fractures à la main, des lacérations de tendons, des morsures et de la ténosynovite infectieuse seront aussi discutées. Les principes de la prise en charge des blessures traumatiques à la main comportent la réduction et l’immobilisation des fractures, la prescription d’imagerie radiographique post-réduction, l’obtention d’un recouvrement par les tissus mous, la prévention et le traitement des infections et l’assurance d’une prophylaxie antitétanique. Conclusion Il est essentiel d’assurer une évaluation et une prise en charge appropriées des blessures traumatiques à la main pour prévenir une morbidité considérable à long terme dans une population autrement en santé. La reconnaissance sans délai des blessures qui nécessitent une demande de consultation urgente ou rapide auprès d’un chirurgien spécialiste de la main est également critique.

Relation entre les caractéristiques des table-bancs et les mesures anthropométriques des écoliers au Benin

PubMed Central

Falola, Stève Marjelin; Gouthon, Polycarpe; Falola, Jean-Marie; Fiogbe, Michel Armand; Nigan, Issiako Bio

2014-01-01

Introduction Le mobilier scolaire et la posture assise en classe sont souvent impliqués dans l'apparition des douleurs rachidiennes, influant de fait sur la qualité des tâches réalisées par les apprenants. Aucune étude n'a encore vérifié le degré d'adéquation entre les caractéristiques du mobilier et celles des écoliers au Bénin. L'objectif de cette étude transversale est donc de déterminer la relation entre les dimensions des table-bancs utilisées en classe et les mesures anthropométriques des écoliers au Bénin. Methods Elle a été réalisée avec un échantillon probabiliste de 678 écoliers, âgés de 4 à 17 ans. Les mesures anthropométriques des écoliers et les mensurations relatives aux longueurs, largeurs et hauteurs des table-bancs ont été mesurées, puis intégrées aux équations proposées dans la littérature. Les pourcentages des valeurs situées hors des limitesacceptables, dérivées de l'application des équations ont été calculés. Results La largeur et la hauteur des table-bancs utilisées par les écoliers étaient plus élevées (p < 0,05) que les valeurs de référence recommandées par les structures officielles de contrôle et de production des mobiliers scolaires au Bénin. Quel que soit le sexe, il y avait une inadéquation entre la largeur du banc et la longueur fesse-poplité, puis entre la hauteur de la table et la distance coude-bancdes écoliers. Conclusion Les résultats suggèrent de prendre en compte l’évolution des mesures anthropométriques des écoliers dans la confection des table-bancs, afin de promouvoir de bonnes postures assises en classe et de réduire le risque de troubles du rachis. PMID:25317232

Guide de pratique clinique pour les lésions cérébrales traumatiques légères et les symptômes persistants

PubMed Central

Marshall, Shawn; Bayley, Mark; McCullagh, Scott; Velikonja, Diana; Berrigan, Lindsay

2012-01-01

Résumé Objectif Présenter les nouvelles lignes directrices sur la prise en charge des lésions cérébrales traumatiques légères (LCTL) et les symptômes persistants post-commotion (SPPC) afin de renseigner et d’orienter les médecins qui prennent en charge des patients qui se remettent d’une LCTL. Qualité des données On a effectué une recherche des guides de pratique clinique existants portant sur les LCTL et une synthèse critique des ouvrages scientifiques évaluant le traitement des SPPC. Étant donné la rareté des conseils sur la prise en charge des SPPC dans les travaux sur les lésions cérébrales traumatiques, une deuxième recherche documentaire a été faite pour recenser les guides de pratique clinique et les synthèses critiques concernant la prise en charge de ces symptômes communs dans la population en général. On a convoqué des professionnels de la santé provenant de différentes disciplines et régions du Canada et de l’étranger à une conférence consensuelle d’experts pour examiner les lignes directrices et les données probantes existantes et élaborer un guide complet pour la prise en charge des LCTL et des SPPC. Message principal À l’aide d’un processus Delphi modifié, on a produit 71 recommandations portant sur le diagnostic et la prise en charge des LCTL et des SPPC. De plus, on a inclus dans le guide de nombreuses ressources et des outils pour faciliter la mise en œuvre des recommandations. Conclusion Un guide de pratique clinique a été élaboré pour aider les professionnels de la santé à fournir des soins fondés sur les données probantes et les pratiques exemplaires à la population complexe de personnes qui ont des SPPC à la suite d’une LCTL.

La singularité du patient tuberculeux dans le système de santé: l'expérience du Burkina Faso

PubMed Central

Zerbo, Roger

2013-01-01

La démarche pluridisciplinaire s'impose de plus en plus dans le secteur de la santé dans le contexte africain, où les parcours thérapeutiques sont pluriels et les rapports des usagers des centres de santé sont complexes et peu satisfaisants. La compréhension des représentations de la maladie est nécessaire pour offrir des soins appropriés certes, mais l'expérience individuelle des malades représente également une source de savoir. Les données ont été collectées à travers des entretiens semi-directifs, le recueil des récits de vie et des observations participantes. Cet article rend compte d'une expérience d'implication de socio-anthropologue dans la mise en œuvre d'un programme de santé publique au Burkina Faso en vue d'une amélioration de la prise en charge des malades tuberculeux. L'analyse des données à été conduite dans une visée réflexive. Les perspectives socio-anthropologiques ont révélé que l'expérience des anciens malades tuberculeux peut être mise à profit afin d'apporter des changements dans les relations thérapeutiques et l'intégration sociale des autres malades. Cette idée à été mise en application pour tenir lieu d'une traduction des analyses anthropologiques en actes pour un changement. L'article évoque la manière dont l'approche socio-anthropologique au sein d'un programme de santé, peut mettre en évidence le potentiel des malades à être des acteurs importants dans le fonctionnement des services de soins et leur propre bien-être. Dans cette situation, la démarche théorique implique la réflexivité de l'anthropologue, mais également un regard critique sur les modes d'intervention en santé publique. PMID:24009798

Influence du comportement des accompagnants sur le vécu des patients admis pour hémorragies digestives hautes au CHU campus de Lomé (Togo)

PubMed Central

Bagny, Aklesso; Dusabe, Angelique; Bouglouga, Oumboma; Lawson-ananisoh, Mawuli Late; Kaaga, Yeba Laconi; Djibril, Mohaman Awalou; Soedje, Kokou Mensah; Dassa, Simliwa Kolou; Redah, Datouda

2014-01-01

Introduction L'hémorragie digestive haute est une urgence, qui constitue souvent pour les patients un danger mortel suscitant inquiétude et agitation. Dans cet état, le patient dépend de ses accompagnants pour ses soins et pour honorer le traitement; mais souvent, il a été observé une discordance entre l'urgence et les comportements des accompagnants. Le but de cette étude était de décrire les facteurs socioéconomiques et psychologiques pouvant influencer les comportements des accompagnants des patients admis pour HDH, estimer l'indice de relation entre ces comportements et les facteurs associés d'une part et le vécu des patients admis pour HDH d'autre part. Méthodes Il s'agit d'une étude prospective menée de Septembre 2010 à Juin 2011 (soit 10 mois). Nous avions utilisé l'entretien semi-dirigé et l'observation directe pour collecter nos données, ces dernières avaient été traitées par les méthodes statistiques et d'analyse de contenu. Résultats Dans la présente étude, les comportements des accompagnants des patients admis pour HDH sont en majorité marqués par l'abandon (84%) et le manque de sollicitude (80,2%). Ces comportements sont souvent stimulés par les facteurs socioéconomiques tels que les difficultés économiques (83,2%), des conflits intrafamiliaux (85,1%) et des représentations (maladie incurable ou envoûtement) de la maladie par les accompagnants (73,3%) des cas. Quant aux patients, ils vivent ces comportements comme étant des menaces de mort ou des rejets (77,20%) et comme étant une dévalorisation ou une humiliation de la part de leurs accompagnants (70,30%). Les résultats confirment l'existence de lien significatif entre les comportements des accompagnants et les facteurs socio économiques, entre les comportements des accompagnants et des facteurs psychologiques, et entre le vécu des patients admis pour l'HDH et les comportements des accompagnants. Conclusion Des études ultérieures devraient aborder les points non touchés dans cette étude. Certes, elle a apporté un plus dans la compréhension du vécu des patients admis pour HDH et des comportements de leurs accompagnants. Cependant, elle est loin d'avoir épuisé les différents contours de la problématique de la présente étude. PMID:25848453

Caracterisation des melanges developpes pour le moulage basse pression des poudres metalliques (LPIM) =

NASA Astrophysics Data System (ADS)

Fareh, Fouad

Le moulage par injection basse pression des poudres metalliques est une technique de fabrication qui permet de fabriquer des pieces possedant la complexite des pieces coulees mais avec les proprietes mecaniques des pieces corroyees. Cependant, l'optimisation des etapes de deliantage et de frittage a ete jusqu'a maintenant effectuee a l'aide de melange pour lesquels la moulabilite optimale n'a pas encore ete demontree. Ainsi, la comprehension des proprietes rheologiques et de la segregation des melanges est tres limitee et cela presente le point faible du processus de LPIM. L'objectif de ce projet de recherche etait de caracteriser l'influence des liants sur le comportement rheologique des melanges en mesurant la viscosite et la segregation des melanges faible viscosite utilises dans le procede LPIM. Afin d'atteindre cet objectif, des essais rheologiques et thermogravimetriques ont ete conduits sur 12 melanges. Ces melanges ont ete prepares a base de poudre d'Inconel 718 de forme spherique (chargement solide constant a 60%) et de cires, d'agents surfactants ou epaississants. Les essais rheologiques ont ete utilises entre autre pour calculer l'indice d'injectabilite ?STV des melanges, tandis que les essais thermogravimetriques ont permis d'evaluer precisement la segregation des poudres dans les melanges. Il a ete demontre que les trois (3) melanges contenant de la cire de paraffine et de l'acide stearique presentent des indices alpha STV plus eleves qui sont avantageux pour le moulage par injection des poudres metalliques (MIM), mais segregent beaucoup trop pour que la piece fabriquee produise de bonnes caracteristiques mecaniques. A l'oppose, le melange contenant de la cire de paraffine et de l'ethylene-vinyle acetate ainsi que le melange contenant seulement de la cire de carnauba segregent peu voire pas du tout, mais possedent de tres faibles indices alphaSTV : ils sont donc difficilement injectables. Le meilleur compromis semble donc etre les melanges contenant de la cire (de paraffine, d'abeille et de carnauba) et de faible teneur en acide stearique et en ethylene-vinyle acetate. Par ailleurs, les lois physiques preexistantes ont permis de confirmer les resultats des essais rheologiques et thermogravimetriques, mais aussi de mettre en evidence l'influence de la segregation sur les proprietes rheologiques des melanges. Ces essais ont aussi montre l'effet de constituants de liant et du temps passe a l'etat fondu sur l'intensite de la segregation dans les melanges. Les melanges contenants de l'acide stearique segregent rapidement. La caracterisation des melanges developpes pour le moulage basse pression des poudres metalliques doit etre obtenue a l'aide d'une methode de courte duree pour eviter la segregation et de mesurer precisement l'aptitude a l'ecoulement de ces melanges.

The role of Heller myotomy and POEM for nonachalasia motility disorders.

PubMed

Schlottmann, F; Shaheen, N J; Madanick, R D; Patti, M G

2017-04-01

The best-defined primary esophageal motor disorder is achalasia. However, symptoms such as dysphagia, regurgitation and chest pain can be caused by other esophageal motility disorders such as Diffuse Esophageal Spasm (DES), Nutcracker Esophagus (NE) and the Hypertensive Lower Esophageal Sphincter (HTN-LES). Most patients with DES and HTN-LES who complain of dysphagia improve after a myotomy. Patients with NE whose main complaint is chest pain, often do not have relief of the pain and can even develop dysphagia as a consequence of the myotomy. POEM is a relatively new procedure, and there are no studies with long-term follow-up and no prospective and randomized trials comparing it to surgical myotomy. Overall, the key to success is based on a complete evaluation and a careful patient selection. The best results, regardless of the technique, are in fact obtained in patients with outflow obstruction and impaired esophageal emptying, a picture similar to achalasia. © The Authors 2017. Published by Oxford University Press on behalf of International Society for Diseases of the Esophagus. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Etude de l'amelioration de la qualite des anodes par la modification des proprietes du brai

NASA Astrophysics Data System (ADS)

Bureau, Julie

La qualite des anodes produites se doit d'etre bonne afin d'obtenir de l'aluminium primaire tout en reduisant le cout de production du metal, la consommation d'energie et les emissions environnementales. Or, l'obtention des proprietes finales de l'anode necessite une liaison satisfaisante entre le coke et le brai. Toutefois, la matiere premiere actuelle n'assure pas forcement la compatibilite entre le coke et le brai. Une des solutions les plus prometteuses, pour ameliorer la cohesion entre ces deux materiaux, est la modification des proprietes du brai. L'objectif de ce travail consiste a modifier les proprietes du brai par l'ajout d'additifs chimiques afin d'ameliorer la mouillabilite du coke par le brai modifie pour produire des anodes de meilleure qualite. La composition chimique du brai est modifiee en utilisant des tensioactifs ou agents de modification de surface choisis dans le but d'enrichir les groupements fonctionnels susceptibles d'ameliorer la mouillabilite. L'aspect economique, l'empreinte environnementale et l'impact sur la production sont consideres dans la selection des additifs chimiques. Afin de realiser ce travail, la methodologie consiste a d'abord caracteriser les brais non modifies, les additifs chimiques et les cokes par la spectroscopie infrarouge a transformee de Fourier (FTIR) afin d'identifier les groupements chimiques presents. Puis, les brais sont modifies en ajoutant un additif chimique afin de possiblement modifier ses proprietes. Differentes quantites d'additif sont ajoutees afin d'examiner l'effet de la variation de la concentration sur les proprietes du brai modifie. La methode FTIR permet d'evaluer la composition chimique des brais modifies afin de constater si l'augmentation de la concentration d'additif enrichit les groupements fonctionnels favorisant l'adhesion coke/brai. Ensuite, la mouillabilite du coke par le brai est observee par la methode goutte- sessile. Une amelioration de la mouillabilite par la modification a l'aide d'un additif chimique signifie une possible amelioration de l'interaction entre le coke et le brai modifie. Afin de completer l'evaluation des donnees recueillies, les resultats de la FTIR et de la mouillabilite sont analyses par le reseau neuronal artificiel afin de mieux comprendre les mecanismes sous-jacents. A la lumiere des resultats obtenus, les additifs chimiques les plus prometteurs sont selectionnes afin de verifier l'effet de leur utilisation sur la qualite des anodes. Pour ce faire, des anodes de laboratoire sont produites en utilisant des brais non modifies et des brais modifies avec les additifs chimiques selectionnes. Par la suite, les anodes sont carottees afin de les caracteriser en determinant certaines de leurs proprietes physiques et chimiques. Enfin, les resultats des echantillons d'anodes faites d'un meme brai non modifie et modifie sont compares afin d'evaluer l'amelioration de la qualite des anodes. Finalement, un examen de l'impact possible de l'utilisation d'un additif chimique pour modifier le brai sur la consommation energetique et en carbone ainsi que la quantite d'aluminium produit est realise. Afin de modifier le brai, trois differents additifs chimiques sont selectionnes, soit un tensioactif et deux agents de modification de surface. L'analyse FTIR des experimentations menees sur les brais modifies demontre que deux additifs ont modifie la composition chimique des brais experimentes. L'analyse des resultats des tests goutte-sessile laisse supposer qu'un brai modifie par ces deux additifs ameliore possiblement l'interaction avec les cokes employes dans cette etude. L'analyse par reseau neuronal artificiel des donnees recueillies permet de mieux comprendre le lien entre la composition chimique d'un brai et sa capacite de mouillabilite avec un coke. La caracterisation des echantillons d'anodes produites permet d'affirmer que ces deux additifs peuvent ameliorer certaines des proprietes anodiques comparativement aux echantillons standards. L'analyse des resultats demontre que l'un des deux additifs semble donner des resultats plus prometteurs. Au final, les travaux realises au cours de ce projet demontrent qu'il est possible d'ameliorer la qualite anodique en modifiant les proprietes du brai. De plus, l'analyse des resultats obtenus fournit une meilleure comprehension des mecanismes entre un brai et un additif chimique.

Les conseils des cliniciens canadiens en matière de commotion dans le sport sont-ils cohérents?

PubMed Central

Carson, James D.; Rendely, Alexandra; Garel, Alisha; Meaney, Christopher; Stoller, Jacqueline; Kaicker, Jatin; Hayden, Leigh; Moineddin, Rahim; Frémont, Pierre

2016-01-01

Résumé Objectif Comparer les connaissances et l’utilisation des recommandations concernant la prise en charge de la commotion dans le sport (CDS) démontrées par les spécialistes de la médecine du sport et de l’exercice (SMSE) et les urgentologues afin d’évaluer la réussite du transfert des connaissances sur la CDS au Canada. Conception Un sondage à choix multiples envoyé par courriel et autoadministré par des SMSE et des urgentologues. La validité du contenu du sondage a fait l’objet d’une évaluation. Contexte Canada. Participants Le sondage a été complété entre mai et juillet 2012 par des SMSE qui ont réussi l’examen menant au diplôme de l’Académie canadienne de la médecine du sport et de l’exercice et des urgentologues qui n’avaient pas ce diplôme. Principaux paramètres à l’étude La connaissance et l’identification des sources d’information sur la prise en charge des commotions, l’utilisation des stratégies de diagnostic de la commotion et l’utilisation d’une terminologie courante et cohérente dans l’explication des stratégies de repos aux patients après une CDS. Résultats Le taux de réponse était de 28 % (305 sur 1085). Les taux de réponse par les SMSE et les urgentologues se situaient respectivement à 41 % (147 sur 360) et 22 % (158 sur 725). Parmi les répondants, 41 % des urgentologues et 3 % des SMSE n’étaient pas au courant de l’existence de déclarations consensuelles sur la commotion dans le sport; 74 % des SMSE utilisaient « habituellement ou toujours » la version 2 de l’Outil d’évaluation de la commotion dans le sport (SCAT2), tandis que 88 % des urgentologues n’utilisaient jamais le SCAT2. Aucune réponse uniforme n’a été documentée à la question visant à connaître les meilleurs modes de repos cognitif. Conclusion Nous avons cerné des différences et un manque d’uniformité chez les SMSE et les urgentologues dans la mise en application des recommandations concernant les patients ayant subi une CDS. Il semble que le SCAT2 soit davantage utilisé dans le milieu des SMSE que dans le contexte de l’urgence. Des efforts plus poussés de transfert des connaissances et en recherche devraient atténuer les obstacles à des conseils plus uniformes donnés par les médecins qui soignent des patients ayant subi une CDS.

Soins primaires aux adultes ayant une déficience développementale

PubMed Central

Sullivan, William F.; Berg, Joseph M.; Bradley, Elspeth; Cheetham, Tom; Denton, Richard; Heng, John; Hennen, Brian; Joyce, David; Kelly, Maureen; Korossy, Marika; Lunsky, Yona; McMillan, Shirley

2011-01-01

Résumé Objectif Mettre à jour les lignes directrices canadiennes de 2006 sur les soins primaires aux adultes ayant une déficience développementale (DD) et présenter des recommandations pratiques fondées sur les connaissances actuelles pour traiter des problèmes de santé particuliers chez des adultes ayant une DD. Qualité des preuves Des professionnels de la santé expérimentés participant à un colloque et un groupe de travail subséquent ont discuté et convenu des révisions aux lignes directrices de 2006 en se fondant sur une recherche documentaire exhaustive, la rétroaction obtenue des utilisateurs du guide de pratique et les expériences cliniques personnelles. La plupart des preuves disponibles dans ce domaine viennent de l’opinion d’experts ou de déclarations consensuelles publiées (niveau III). Message principal Les adultes ayant une DD ont des problèmes de santé complexes, dont plusieurs diffèrent de ceux de la population en général. De bons soins primaires permettent d’identifier les problèmes de santé particuliers dont souffrent les adultes ayant une DD pour améliorer leur qualité de vie et leur accès aux soins de santé et prévenir la morbidité et le décès prématuré. Ces lignes directrices résument les problèmes de santé générale, physique, comportementale et mentale des adultes ayant une DD que devraient connaître les professionnels des soins primaires et présentent des recommandations pour le dépistage et la prise en charge en se basant sur les connaissances actuelles que les cliniciens peuvent mettre en pratique. En raison de l’interaction des facteurs biologiques, psychoaffectifs et sociaux qui contribuent à la santé et au bien-être des adultes ayant une DD, ces lignes directrices insistent sur la participation des aidants, l’adaptation des interventions, au besoin, et la consultation auprès de divers professionnels de la santé quand ils sont accessibles. Elles mettent aussi en évidence la nature éthique des soins. Les lignes directrices sont formulées dans le contexte d’un cadre éthique qui tient compte des questions comme le consentement éclairé et l’évaluation des bienfaits pour la santé par rapport aux risques de préjudice. Conclusion La mise en œuvre des lignes directrices proposées ici améliorerait la santé des adultes ayant une DD et minimiserait les disparités sur les plans de la santé et des soins de santé entre les adultes ayant une DD et la population en général.

Prenatal diethylstilbestrol induces malformation of the external genitalia of male and female mice and persistent second-generation developmental abnormalities of the external genitalia in two mouse strains

PubMed Central

Mahawong, Phitsanu; Sinclair, Adriane; Li, Yi; Schlomer, Bruce; Rodriguez, Esequiel; Max, Ferretti M.; Liu, Baomei; Baskin, Laurence S.; Cunha, Gerald R.

2014-01-01

Potential trans-generational influence of diethylstilbestrol (DES) exposure emerged with reports of effects in grandchildren of DES-treated pregnant women and of reproductive tract tumors in offspring of mice exposed in utero to DES. Accordingly, we examined the trans-generational influence of DES on development of external genitalia (ExG) and compared effects of in utero DES exposure in CD-1 and C57BL/6 mice injected with oil or DES every other day from gestational days 12 to 18. Mice were examined at birth, and on 5 to 120 days postnatal to evaluate ExG malformations. Of 23 adult (≥60 days) prenatally DES-exposed males, features indicative of urethral meatal hypospadias (see text for definitions) ranged from 18 to 100% in prenatally DES-exposed CD-1 males and 31 to 100% in prenatally DES-exposed C57BL/6 males. Thus, the strains differed in the incidence of male urethral hypospadias. Ninety-one percent of DES-exposed CD-1 females and 100% of DES-exposed C57BL/6 females had urethral-vaginal fistula. All DES-exposed CD-1 and C57BL/6 females lacked an os clitoris. None of the prenatally oil-treated CD-1 and C57BL/6 male and female mice had ExG malformations. For the second-generation study, 10 adult CD-1 males and females, from oil- and DES-exposed groups, respectively, were paired with untreated CD-1 mice for 30 days, and their offspring evaluated for ExG malformations. None of the F1 DES-treated females were fertile. Nine of 10 prenatally DES-exposed CD-1 males sired offspring with untreated females, producing 55 male and 42 female pups. Of the F2 DES-lineage adult males, 20% had exposed urethral flaps, a criterion of urethral meatal hypospadias. Five of 42 (11.9%) F2 DES lineage females had urethral-vaginal fistula. In contrast, all F2 oil-lineage males and all oil-lineage females were normal. Thus, prenatal DES exposure induces malformations of ExG in both sexes and strains of mice, and certain malformations are transmitted to the second-generation. PMID:25449352

Methodes iteratives paralleles: Applications en neutronique et en mecanique des fluides

NASA Astrophysics Data System (ADS)

Qaddouri, Abdessamad

Dans cette these, le calcul parallele est applique successivement a la neutronique et a la mecanique des fluides. Dans chacune de ces deux applications, des methodes iteratives sont utilisees pour resoudre le systeme d'equations algebriques resultant de la discretisation des equations du probleme physique. Dans le probleme de neutronique, le calcul des matrices des probabilites de collision (PC) ainsi qu'un schema iteratif multigroupe utilisant une methode inverse de puissance sont parallelises. Dans le probleme de mecanique des fluides, un code d'elements finis utilisant un algorithme iteratif du type GMRES preconditionne est parallelise. Cette these est presentee sous forme de six articles suivis d'une conclusion. Les cinq premiers articles traitent des applications en neutronique, articles qui representent l'evolution de notre travail dans ce domaine. Cette evolution passe par un calcul parallele des matrices des PC et un algorithme multigroupe parallele teste sur un probleme unidimensionnel (article 1), puis par deux algorithmes paralleles l'un mutiregion l'autre multigroupe, testes sur des problemes bidimensionnels (articles 2--3). Ces deux premieres etapes sont suivies par l'application de deux techniques d'acceleration, le rebalancement neutronique et la minimisation du residu aux deux algorithmes paralleles (article 4). Finalement, on a mis en oeuvre l'algorithme multigroupe et le calcul parallele des matrices des PC sur un code de production DRAGON ou les tests sont plus realistes et peuvent etre tridimensionnels (article 5). Le sixieme article (article 6), consacre a l'application a la mecanique des fluides, traite la parallelisation d'un code d'elements finis FES ou le partitionneur de graphe METIS et la librairie PSPARSLIB sont utilises.

Mise au point du rheometre a cisaillement annulaire pour l'etude de rheologie d'un mastic bitumineux avec verre incorpore =

NASA Astrophysics Data System (ADS)

El Mansouri, Souleimane

Dans le domaine viscoelastique lineaire (VEL, domaine des petites deformations), le comportement thermomecanique du bitume et du mastic bitumineux (melange uniforme de bitume et de fillers) a ete caracterise au Laboratoire des Chaussees et Materiaux Bitumineux (LCMB) de l'Ecole de technologie superieure (ETS) avec l'appui de nos partenaires externes : la Societe des Alcools du Quebec (SAQ) et Eco Entreprises Quebec (EEQ). Les proprietes rheologiques des bitumes et des mastics ont ete mesurees grâce a un nouvel outil d'investigation appele, Rheometre a Cisaillement Annulaire (RCA), sous differentes conditions de chargement. Cet appareil permet non seulement de solliciter des eprouvettes de tailles importantes par rapport a celles utilisees lors des essais classiques, mais aussi d'effectuer des essais en conditions quasi-homogenes, ce qui permet de donner acces a la loi de comportement des materiaux. Les essais sont realises sur une large gamme de temperatures et de frequences (de -15 °C a 45°C et de 0,03Hz a 10 Hz). Cette etude a ete menee principalement pour comparer le comportement d'un bitume avec celui d'un mastic bitumineux dans le domaine des petites deformations. neanmoins, dans une seconde perspective, on s'interesse a l'influence des fillers de verre de post-consommation sur le comportement d'un mastic a faibles niveaux de deformations en comparant l'evolution des modules complexes de cisaillements (G*) d'un mastic avec fillers de verre et un mastic avec fillers conventionnels (calcaire). Enfin, le modele analogique 2S2P1D est utilise pour simuler le comportement viscoelastique lineaire des bitumes et des mastics bitumineux testes lors de la campagne experimentale.

Membrane fluidization by alcohols inhibits DesK-DesR signalling in Bacillus subtilis.

PubMed

Vaňousová, Kateřina; Beranová, Jana; Fišer, Radovan; Jemioła-Rzemińska, Malgorzata; Matyska Lišková, Petra; Cybulski, Larisa; Strzałka, Kazimierz; Konopásek, Ivo

2018-03-01

After cold shock, the Bacillus subtilis desaturase Des introduces double bonds into the fatty acids of existing membrane phospholipids. The synthesis of Des is regulated exclusively by the two-component system DesK/DesR; DesK serves as a sensor of the state of the membrane and triggers Des synthesis after a decrease in membrane fluidity. The aim of our work is to investigate the biophysical changes in the membrane that are able to affect the DesK signalling state. Using linear alcohols (ethanol, propanol, butanol, hexanol, octanol) and benzyl alcohol, we were able to suppress Des synthesis after a temperature downshift. The changes in the biophysical properties of the membrane caused by alcohol addition were followed using membrane fluorescent probes and differential scanning calorimetry. We found that the membrane fluidization induced by alcohols was reflected in an increased hydration at the lipid-water interface. This is associated with a decrease in DesK activity. The addition of alcohol mimics a temperature increase, which can be measured isothermically by fluorescence anisotropy. The effect of alcohols on the membrane periphery is in line with the concept of the mechanism by which two hydrophilic motifs located at opposite ends of the transmembrane region of DesK, which work as a molecular caliper, sense temperature-dependent variations in membrane properties. Copyright © 2017 Elsevier B.V. All rights reserved.

Le patrimoine astronomique provençal

NASA Astrophysics Data System (ADS)

Rous, M.; Figon, P.; Guyot, S.

2012-12-01

L'OSU OAMP/Institut Pythéas porte les missions de conservation, inventaire et valorisation du patrimoine. Suite à la fusion de l'Observatoire de Marseille et du Laboratoire d'Astronomie Spatiale en 2000 pour créer le Laboratoire d'Astrophysique de Marseille, le déménagement des équipes sur le site de Château-Gombert en 2008 a soulevé le problème du devenir des collections des deux sites d'origine. Nous ferons le bilan des actions passées en matière de conservation et de valorisation de ce riche patrimoine : versement à l'inventaire général du Ministère de la Culture, classement de 22 instruments au titre des Monuments Historiques, inventaire et numérisation des archives anciennes, montage d'expositions et réalisation du catalogue Telescopium, 400 ans de lunettes et de télescopes. Nous présenterons les actions en cours: mesures de conservation préventive, inventaire des archives et des instruments. Nous parlerons enfin des projets: création d'un espace d'exposition permanente, participation à des expositions temporaires.

Préface

NASA Astrophysics Data System (ADS)

Schober, Helmut; Fischer, Henry; Leclercq-Hugeux, Françoise

2003-09-01

L'École Thématique “Structure et Dynamique des Systèmes Désordonnés” [1] s'inscrit dans le cadre des écoles organisées sous l'impulsion de la Société Française de la Neutronique (SFN). Elle s'est deroulée en mai 2002 sur la Presqu'île de Giens (Var) en première partie des 11émes Journées de la Diffusion Neutronique. L'Édition de ces cours constitue ainsi le cinquième ouvrage introduisant les techniques neutroniques et leurs apports à differentes thématiques [2]. Le désordre est un facteur déterminant pour pratiquement toutes les propriétés des matériaux. Il est inhérent dans les matériaux amorphes ou liquides, mais il détermine également les propriétés mécaniques et électroniques d'autres composés d'importance technologique comme les matériaux métalliques, dont l'aspect “désordonné” est moins évident. Le désordre enfin joue un rôle essentiel dans tout ce que touche à la vie. En fait, il est difficile d'imaginer des systèmes, à part quelques exceptions rares comme l'hélium ou le silicium de haute pureté, où il n'y ait pas de désordre. En dehors de cet aspect pratique, la description scientifique du désordre atomique pose toujours des problèmes fondamentaux faute de concepts pertinents. Une des tâches importantes du scientifique ou de l'ingenieur est de préciser quel genre de désordre existe à une échelle d'espace et de temps donnée. Un materiau peut très bien être homogène à l'échelle atomique et présenter des défauts ou des hétrogéneité visibles à l'œil et inversement. De même, un système désordonné à un instant donné, peut apparaître ordonné si on moyenne dans le temps. Les techniques de diffusion des neutrons sont idéales pour aborder ces questions. Les neutrons sondent directement les noyaux et ont à la fois des longueurs d'ondes proches des distances inter atomiques et des énergies avoisinant celles des excitations élémentaires de la matière condensée. Ils permettent ainsi une observation directe et non-destructive des positions et des mouvements atomiques. La gamme des distances et des temps sondés par les neutrons autorisent aussi bien de suivre le mouvement des atomes à l'échelle inter atomique que l'évolution d'une structure soit mésoscopique soit macroscopique sur des temps de moins d'une picoseconde à plusieurs heures. La gamme des techniques de diffusion utilisées pour couvrir un tel champ d'application est naturellement très large : différents types de diffractomètres permettent des études de structure atomique trés pointue et résolue dans le temps. Les spectromètres nous donnent accès à la dynamique d'une dizaine de femto- à plusieurs nanosecondes. La diffusion aux petits angles, la reflectomètrie et finalement la tomographie nous permettent de regarder la structure et la dynamique d'objets plus grands. Il était illusoire de prétendre couvrir la totalité des systèmes désordonnés et l'ensemble des techniques de diffusion neutronique pertinentes au cours d'une école de 3 jours. Nous avons donc été amené à nous concentrer sur les liquides, les verres, les cristaux plastiques et les polymères. Ce choix s'est imposé par le souhait d'introduire les concepts de base, en acceptant de sacrifier certains domaines d'applications. Il va de soi que l'étude approfondie de systèmes mettant en jeu plusieurs échelles de distance (structure moléculaire, portée des corrélations entre les molécules) et de temps (relaxations caractéristiques des divers phenomènes dynamiques selon leur extension spatiale) implique une pluralité de techniques expérimentales, complémentaires des différentes techniques neutroniques disponibles. Un des objectifs de cette école etait donc de préciser les domaines de pertinence des différentes techniques neutroniques disponibles en en situant la complémentarité avec d'autres approches instrumentales (diffraction des rayons X, EXAFS, RMN, etc.). Enfin la confrontation avec les résultats obtenus par simulation et modélisation numérique est essentielle à la compréhension des processus élémentaires dans ces systèmes complexes. En première partie de cet ouvrage, on trouvera une description géntrale des systèmes désordonnés et une introduction aux techniques de diffusion de neutrons. Pour la partie concernant la structure, une revue des techniques de diffraction est suivie par des applications à des systèmes de complexité croissante (liquides métalliques simples, alliages liquides, semiconducteurs fondus, solutions aqueuses, verres d'oxydes). L'apport des méthodes de variation de longueur de diffusion (substitution isotopique pour les mesures aux neutrons, diffusion anomale des rayons X ou combinaison de ces deux techniques) permet la détermination des facteurs de structures partiels. Pour la dynamique, on a privilégié une approche introduisant progressivement le désordre en passant des solides aux liquides. Le concept de diffusion puis les particularités dynamiques des verres sont ensuite présentés et illustrés par des exemples concrets. Enfin la dernière partie est consacrée à la simulation numérique des propriétés dynamiques des verres et des liquides et à la modélisation de la structure par méthode de Monte Carlo inverse (RMC) à partir de l'ensemble des données expérimentales existant pour un système donné. La communauté française a joué un rôle important dans le développement des techniques neutroniques dédites à l'étude des systèmes désordonnés et y a acquis une competence reconnue. Nous avons essayé, dans cet ouvrage, de privilégier les aspects pédagogiques des cours, pour les rendre accessibles aux scientifiques francophones non spécialistes en diffusion des neutrons. Nous saluons ici l'effort de rédaction, en langue française, des différents intervenants et souhaitons que cet ouvrage puisse participer à la formation et au renouvellement de la communauté neutronique française. Helmut Schober et Henry Fischer (Editeurs scientifiques) Françoise Leclercq-Hugeux (Présidente de la SFN)

Quantification des besoins en intrants antipaludiques: contribution à l'actualisation des hypothèses pour la quantification des intrants de prise en charge des cas de paludisme grave en République Démocratique du Congo

PubMed Central

Likwela, Joris Losimba; Otokoye, John Otshudiema

2015-01-01

Les formes graves de paludisme à Plasmodium falciparum sont une cause majeure de décès des enfants de moins de 5 ans en Afrique Sub-saharienne. Un traitement rapide dépend de la disponibilité de médicaments appropriés au niveau des points de prestation de service. La fréquence des ruptures de stock des commodités antipaludiques, en particuliers celles utilisées pour le paludisme grave, avait nécessité une mise à jour des hypothèses de quantification. Les données issues de la collecte de routine du PNLP de 2007 à 2012 ont été comparées à celles rapportés par d'autres pays africains et utilisées pour orienter les discussions au cours d'un atelier organisé par le PNLP et ses partenaires techniques et financiers afin de dégager un consensus national. La proportion des cas de paludisme rapportés comme grave en RDC est resté autour d'une médiane de 7% avec un domaine de variation de 6 à 9%. Hormis la proportion rapportée au Kenya (2%), les pays africains ont rapporté une proportion de cas grave variant entre 5 et 7%. Il apparaît que la proportion de 1% précédemment utilisée pour la quantification en RDC a été sous-estimée dans le contexte de la gestion des cas graves sur terrain. Un consensus s'est dégagé autour de la proportion de 5% étant entendu que des efforts de renforcement des capacités seraient déployés afin d'améliorer le diagnostic au niveau des points de prestation des services. PMID:26213595

Soins primaires aux adultes ayant des déficiences intellectuelles et développementales

PubMed Central

Sullivan, William F.; Diepstra, Heidi; Heng, John; Ally, Shara; Bradley, Elspeth; Casson, Ian; Hennen, Brian; Kelly, Maureen; Korossy, Marika; McNeil, Karen; Abells, Dara; Amaria, Khush; Boyd, Kerry; Gemmill, Meg; Grier, Elizabeth; Kennie-Kaulbach, Natalie; Ketchell, Mackenzie; Ladouceur, Jessica; Lepp, Amanda; Lunsky, Yona; McMillan, Shirley; Niel, Ullanda; Sacks, Samantha; Shea, Sarah; Stringer, Katherine; Sue, Kyle; Witherbee, Sandra

2018-01-01

Résumé Objectif Mettre à jour les Lignes directrices consensuelles canadiennes 2011 en matière de soins primaires aux adultes ayant une déficience développementale. Méthodes Des médecins de famille et d’autres professionnels de la santé expérimentés dans les soins aux personnes ayant des DID ont examiné et synthétisé les récentes connaissances empiriques, d’écosystèmes, expertes et expérientielles. Un système a été conçu pour catégoriser la qualité des recommandations. Recommandations Les adultes ayant des DID sont un groupe hétérogène de patients qui présentent des affections médicales et des facteurs qui influent sur leur santé, qui diffèrent de ceux qui touchent les autres membres de la communauté de par leur nature, leurs manifestations, leur gravité ou leur complexité. Ces personnes nécessitent une approche de soins et des interventions adaptées à leurs besoins. Les présentes lignes directrices offrent des conseils en matière de normes de soins. Nous avons incorporé des références à des outils cliniques et à d’autres ressources pratiques. Les approches de soins décrites ici s’appliquent aussi à d’autres groupes de patients ayant un déficit cognitif ou de la communication, ou d’autres déficits des fonctions adaptatives. Conclusion À titre de fournisseurs de soins de première ligne, les médecins de famille jouent un rôle vital de promotion de la santé et de bien-être auprès des adultes ayant des DID. Ces lignes directrices peuvent les aider à prendre des décisions avec les patients et les aidants naturels. PMID:29650617

Effets de l'humidite sur la propagation du delaminage dans un composite carbone/epoxy sollicite en mode mixte I/II

NASA Astrophysics Data System (ADS)

LeBlanc, Luc R.

Les materiaux composites sont de plus en plus utilises dans des domaines tels que l'aerospatiale, les voitures a hautes performances et les equipements sportifs, pour en nommer quelques-uns. Des etudes ont demontre qu'une exposition a l'humidite nuit a la resistance des composites en favorisant l'initiation et la propagation du delaminage. De ces etudes, tres peu traitent de l'effet de l'humidite sur l'initiation du delaminage en mode mixte I/II et aucune ne traite des effets de l'humidite sur le taux de propagation du delaminage en mode mixte I/II dans un composite. La premiere partie de cette these consiste a determiner les effets de l'humidite sur la propagation du delaminage lors d'une sollicitation en mode mixte I/II. Des eprouvettes d'un composite unidirectionnel de carbone/epoxy (G40-800/5276-1) ont ete immergees dans un bain d'eau distillee a 70°C jusqu'a leur saturation. Des essais experimentaux quasi-statiques avec des chargements d'une gamme de mixites des modes I/II (0%, 25%, 50%, 75% et 100%) ont ete executes pour determiner les effets de l'humidite sur la resistance au delaminage du composite. Des essais de fatigue ont ete realises, avec la meme gamme de mixite des modes I/II, pour determiner 1'effet de 1'humidite sur l'initiation et sur le taux de propagation du delaminage. Les resultats des essais en chargement quasi-statique ont demontre que l'humidite reduit la resistance au delaminage d'un composite carbone/epoxy pour toute la gamme des mixites des modes I/II, sauf pour le mode I ou la resistance au delaminage augmente apres une exposition a l'humidite. Pour les chargements en fatigue, l'humidite a pour effet d'accelerer l'initiation du delaminage et d'augmenter le taux de propagation pour toutes les mixites des modes I/II. Les donnees experimentales recueillies ont ete utilisees pour determiner lesquels des criteres de delaminage en statique et des modeles de taux de propagation du delaminage en fatigue en mode mixte I/II proposes dans la litterature representent le mieux le delaminage du composite etudie. Une courbe de regression a ete utilisee pour determiner le meilleur ajustement entre les donnees experimentales et les criteres de delaminage en statique etudies. Une surface de regression a ete utilisee pour determiner le meilleur ajustement entre les donnees experimentales et les modeles de taux de propagation en fatigue etudies. D'apres les ajustements, le meilleur critere de delaminage en statique est le critere B-K et le meilleur modele de propagation en fatigue est le modele de Kenane-Benzeggagh. Afin de predire le delaminage lors de la conception de pieces complexes, des modeles numeriques peuvent etre utilises. La prediction de la longueur de delaminage lors des chargements en fatigue d'une piece est tres importante pour assurer qu'une fissure interlaminaire ne va pas croitre excessivement et causer la rupture de cette piece avant la fin de sa duree de vie de conception. Selon la tendance recente, ces modeles sont souvent bases sur l'approche de zone cohesive avec une formulation par elements finis. Au cours des travaux presentes dans cette these, le modele de progression du delaminage en fatigue de Landry & LaPlante (2012) a ete ameliore en y ajoutant le traitement des chargements en mode mixte I/II et en y modifiant l'algorithme du calcul de la force d'entrainement maximale du delaminage. Une calibration des parametres de zone cohesive a ete faite a partir des essais quasi-statiques experimentaux en mode I et II. Des resultats de simulations numeriques des essais quasi-statiques en mode mixte I/II, avec des eprouvettes seches et humides, ont ete compares avec les essais experimentaux. Des simulations numeriques en fatigue ont aussi ete faites et comparees avec les resultats experimentaux du taux de propagation du delaminage. Les resultats numeriques des essais quasi-statiques et de fatigue ont montre une bonne correlation avec les resultats experimentaux pour toute la gamme des mixites des modes I/II etudiee.

19 CFR 148.13 - Written declarations.

Code of Federal Regulations, 2010 CFR

2010-04-01

...) When required. Unless an oral declaration is accepted under § 148.12, the declaration required of a..., HTSUS, for articles to be disposed of as bona fide gifts; or subheading 9804.00.40, HTSUS, for articles... passenger shall state either: (1) The price actually paid for the article in the currency of purchase, or...

21 CFR 201.312 - Magnesium sulfate heptahydrate; label declaration on drug products.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 21 Food and Drugs 4 2011-04-01 2011-04-01 false Magnesium sulfate heptahydrate; label declaration... Drug Products § 201.312 Magnesium sulfate heptahydrate; label declaration on drug products. Magnesium sulfate heptahydrate should be listed on the label of a drug product as epsom salt, which is its common or...

21 CFR 201.312 - Magnesium sulfate heptahydrate; label declaration on drug products.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 21 Food and Drugs 4 2014-04-01 2014-04-01 false Magnesium sulfate heptahydrate; label declaration... Drug Products § 201.312 Magnesium sulfate heptahydrate; label declaration on drug products. Magnesium sulfate heptahydrate should be listed on the label of a drug product as epsom salt, which is its common or...

21 CFR 201.312 - Magnesium sulfate heptahydrate; label declaration on drug products.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 4 2010-04-01 2010-04-01 false Magnesium sulfate heptahydrate; label declaration... Drug Products § 201.312 Magnesium sulfate heptahydrate; label declaration on drug products. Magnesium sulfate heptahydrate should be listed on the label of a drug product as epsom salt, which is its common or...

21 CFR 201.312 - Magnesium sulfate heptahydrate; label declaration on drug products.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 21 Food and Drugs 4 2012-04-01 2012-04-01 false Magnesium sulfate heptahydrate; label declaration... Drug Products § 201.312 Magnesium sulfate heptahydrate; label declaration on drug products. Magnesium sulfate heptahydrate should be listed on the label of a drug product as epsom salt, which is its common or...

21 CFR 201.312 - Magnesium sulfate heptahydrate; label declaration on drug products.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 21 Food and Drugs 4 2013-04-01 2013-04-01 false Magnesium sulfate heptahydrate; label declaration... Drug Products § 201.312 Magnesium sulfate heptahydrate; label declaration on drug products. Magnesium sulfate heptahydrate should be listed on the label of a drug product as epsom salt, which is its common or...

76 FR 59766 - New York Disaster Number NY-00110

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2011-09-27

... SMALL BUSINESS ADMINISTRATION [Disaster Declaration 12824 and 12825] New York Disaster Number NY... the Presidential declaration of a major disaster for the State of New York (FEMA-4031-DR), dated 09/13... declaration for the State of New York, dated 09/13/2011 is hereby amended to include the following areas as...

77 FR 71666 - New York Disaster Number NY-00130

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2012-12-03

... SMALL BUSINESS ADMINISTRATION [Disaster Declaration 13365 and 13366] New York Disaster Number NY... the Presidential declaration of a major disaster for the State of New York (FEMA-4085-DR), dated 10/30... declaration for the State of New York, dated 10/30/2012 is hereby amended to establish the incident period for...

78 FR 7848 - New York Disaster Number NY-00130

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2013-02-04

... SMALL BUSINESS ADMINISTRATION [Disaster Declaration 13365 and 13366] New York Disaster Number NY... the Presidential declaration of a major disaster for the State of New York (FEMA-4085-DR), dated 10/30... disaster declaration for the State of New York, dated 10/30/2012 is hereby amended to extend the deadline...

76 FR 59176 - New York Disaster Number NY-00110

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2011-09-23

... SMALL BUSINESS ADMINISTRATION [Disaster Declaration 12824 and 12825] New York Disaster Number NY... the Presidential declaration of a major disaster for the State of New York (FEMA-4031-DR), dated 09/13... disaster declaration for the State of New York, dated 09/13/2011 is hereby amended to include the following...

76 FR 59178 - New York Disaster Number NY-00108

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2011-09-23

... SMALL BUSINESS ADMINISTRATION [Disaster Declaration 12776 and 12777] New York Disaster Number NY... the Presidential declaration of a major disaster for the State of New York (FEMA-4020-DR), dated 08/31... declaration for the State of New York, dated 08/31/2011 is hereby amended to include the following areas as...

76 FR 68804 - New York Disaster Number NY-00110

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2011-11-07

... SMALL BUSINESS ADMINISTRATION [Disaster Declaration 12824 and 12825] New York Disaster Number NY... the Presidential declaration of a major disaster for the State of New York (FEMA-4031-DR), dated 09/13... major disaster declaration for the State of New York, dated 09/13/2011 is hereby amended to extend the...

78 FR 15109 - New York Disaster Number NY-00130

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... SMALL BUSINESS ADMINISTRATION [Disaster Declaration 13365 and 13366] New York Disaster Number NY... the Presidential declaration of a major disaster for the State of New York (FEMA-4085-DR), dated 10/30... major disaster declaration for the State of New York, dated 10/30/2012 is hereby amended to extend the...

76 FR 64420 - NEW YORK Disaster Number NY-00110

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2011-10-18

... SMALL BUSINESS ADMINISTRATION [Disaster Declaration 12824 and 12825] NEW YORK Disaster Number NY... the Presidential declaration of a major disaster for the State of New York (FEMA-4031-DR), dated 09/13... disaster declaration for the State of NEW YORK, dated 09/13/2011 is hereby amended to include the following...

76 FR 63700 - New York Disaster Number NY-00110

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2011-10-13

... SMALL BUSINESS ADMINISTRATION [Disaster Declaration 12824 and 12825] New York Disaster Number NY... the Presidential declaration of a major disaster for the State of New York (FEMA-4031-DR), dated 09/13... disaster declaration for the State of New York, dated 09/13/2011 is hereby amended to include the following...

76 FR 58328 - New York Disaster Number NY-00108

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2011-09-20

... SMALL BUSINESS ADMINISTRATION [Disaster Declaration 12776 and 12777] New York Disaster Number NY... the Presidential declaration of a major disaster for the State of New York (FEMA-4020-DR), dated 08/31... declaration for the State of New York, dated 08/31/2011 is hereby amended to include the following areas as...

76 FR 58329 - New York Disaster Number NY-00108

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2011-09-20

... SMALL BUSINESS ADMINISTRATION [Disaster Declaration 12776 and 12777] New York Disaster Number NY... the Presidential declaration of a major disaster for the State of New York (FEMA-4020-DR), dated 08/31... declaration for the State of NEW YORK, dated 08/31/2011, is hereby amended to include the following areas as...

76 FR 67245 - New York Disaster Number NY-00110

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2011-10-31

... SMALL BUSINESS ADMINISTRATION [Disaster Declaration 12824 and 12825] New York Disaster Number NY... the Presidential declaration of a major disaster for the State of New York (FEMA-4031-DR), dated 09/13... disaster declaration for the State of New York, dated 09/13/2011 is hereby amended to include the following...

76 FR 68803 - New York Disaster Number NY-00108

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2011-11-07

... SMALL BUSINESS ADMINISTRATION [Disaster Declaration 12776 and 12777] New York Disaster Number NY... the Presidential declaration of a major disaster for the State of New York (FEMA-4020-DR), dated 08/31... disaster declaration for the State of New York, dated 08/31/2011 is hereby amended to extend the deadline...

77 FR 74907 - New York Disaster Number NY-00130

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2012-12-18

... SMALL BUSINESS ADMINISTRATION [Disaster Declaration 13365 and 13366] New York Disaster Number NY... the Presidential declaration of a major disaster for the State of New York (FEMA-4085-DR), dated 10/30... disaster declaration for the State of New York, dated 10/30/2012 is hereby amended to extend the deadline...

78 FR 20370 - New York Disaster Number NY-00130

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2013-04-04

... SMALL BUSINESS ADMINISTRATION [Disaster Declaration 13365 and 13366] New York Disaster Number NY... the Presidential declaration of a major disaster for the State of New York (FEMA-4085-DR), dated 10/30... Disaster Declaration For The State Of New York, dated 10/30/2012 is hereby amended to extend the deadline...

21 CFR 701.13 - Declaration of net quantity of contents.

Code of Federal Regulations, 2010 CFR

2010-04-01

... typography, layout, color, embossing, or molding) to other matter on the package; except that a declaration of net quantity blown, embossed, or molded on a glass or plastic surface is permissible when all... inches. Where the declaration is blown, embossed, or molded on a glass or plastic surface rather than by...

21 CFR 801.62 - Declaration of net quantity of contents.

Code of Federal Regulations, 2010 CFR

2010-04-01

..., embossing, or molding) to other matter on the package; except that a declaration of net quantity blown, embossed, or molded on a glass or plastic surface is permissible when all label information is so formed on.... Where the declaration is blown, embossed, or molded on a glass or plastic surface rather than by...

Sleep in Children Enhances Preferentially Emotional Declarative But Not Procedural Memories

ERIC Educational Resources Information Center

Prehn-Kristensen, Alexander; Goder, Robert; Chirobeja, Stefania; Bressman, Inka; Ferstl, Roman; Baving, Lioba

2009-01-01

Although the consolidation of several memory systems is enhanced by sleep in adults, recent studies suggest that sleep supports declarative memory but not procedural memory in children. In the current study, the influence of sleep on emotional declarative memory (recognition task) and procedural memory (mirror tracing task) in 20 healthy children…

78 FR 16521 - Agency Information Collection Activities: Declaration for Free Entry of Unaccompanied Articles

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2013-03-15

... Activities: Declaration for Free Entry of Unaccompanied Articles AGENCY: U.S. Customs and Border Protection...: Declaration for Free Entry of Unaccompanied Articles (Form 3299). This is a proposed extension of an... Unaccompanied Articles. OMB Number: 1651-0014. Form Number: Form 3299. Abstract: 19 U.S.C. 1498 provides that...

75 FR 28313 - Mississippi Disaster #MS-00038 Declaration of Economic Injury

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2010-05-20

... Declaration of Economic Injury AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This is a notice of an Economic Injury Disaster Loan (EIDL) declaration for the State of Mississippi, dated 05/13... economic injury disaster loans may be filed at the address listed above or other locally announced...

76 FR 19515 - California Disaster # CA-00170 Declaration of Economic Injury

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2011-04-07

... Declaration of Economic Injury AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This is a notice of an Economic Injury Disaster Loan (EIDL) declaration for the State of California, dated 03/31..., applications for economic injury disaster loans may be filed at the address listed above or other locally...

75 FR 17792 - North Carolina Disaster # NC-00025 Declaration of Economic Injury

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2010-04-07

... Declaration of Economic Injury AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This is a notice of an Economic Injury Disaster Loan (EIDL) declaration for the State of North Carolina, dated 03..., applications for economic injury disaster loans may be filed at the address listed above or other locally...

75 FR 26813 - New Hampshire Disaster #NH-00016 Declaration of Economic Injury

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2010-05-12

... Declaration of Economic Injury AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This is a notice of an Economic Injury Disaster Loan (EIDL) declaration for the State of New Hampshire, dated 05/04... economic injury disaster loans may be filed at the address listed above or other locally announced...

76 FR 59176 - New Mexico Disaster #NM-00023 Declaration of Economic Injury

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2011-09-23

... Declaration of Economic Injury AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This is a notice of an Economic Injury Disaster Loan (EIDL) declaration for the State of New Mexico, dated 09/13... economic injury disaster loans may be filed at the address listed above or other locally announced...

78 FR 57922 - New Mexico Disaster #NM-00034 Declaration of Economic Injury

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2013-09-20

... Declaration of Economic Injury AGENCY: Small Business Administration. ACTION: Notice. SUMMARY: This is a notice of an Economic Injury Disaster Loan (EIDL) declaration for the State of New Mexico, dated 09/10..., applications for economic injury disaster loans may be filed at the address listed above or other locally...

78 FR 57923 - Colorado Disaster #CO-00058 Declaration of Economic Injury

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2013-09-20

... of Economic Injury AGENCY: Small Business Administration. ACTION: Amendment 1. SUMMARY: This is an amendment of the Economic Injury Disaster Loan (EIDL) declaration for the State of Colorado, dated 09/12... INFORMATION: The notice of the Economic Injury declaration for the State of Colorado dated 07/15/2013, is...

78 FR 52599 - New Mexico Disaster #NM-00033 Declaration of Economic Injury

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2013-08-23

... Declaration of Economic Injury AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This is a notice of an Economic Injury Disaster Loan (EIDL) declaration for the State of New Mexico, dated 08/13..., applications for economic injury disaster loans may be filed at the address listed above or other locally...

78 FR 53492 - California Disaster #CA-00208 Declaration of Economic Injury

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2013-08-29

... Declaration of Economic Injury AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This is a notice of an Economic Injury Disaster Loan (EIDL) declaration for the State of California, dated 08/19... economic injury disaster loans may be filed at the address listed above or other locally announced...

78 FR 65745 - Oregon Disaster #OR-00051 Declaration of Economic Injury

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2013-11-01

... Economic Injury AGENCY: U.S. Small Business Administration. ACTION: Amendment 1. SUMMARY: This is a notice of an Economic Injury Disaster Loan (EIDL) declaration for the State of Oregon, dated 09/06/2013...: The notice of the Economic Injury declaration for the State of Oregon dated 09/06/2013 is hereby...

78 FR 35309 - Illinois; Amendment No. 3 to Notice of a Major Disaster Declaration

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2013-06-12

..., Henderson, Kendall, Knox, Lake, LaSalle, Livingston, Marshall, Mason, McHenry, Pike, Rock Island, Stark, and... Declaration AGENCY: Federal Emergency Management Agency, DHS. ACTION: Notice. SUMMARY: This notice amends the notice of a major disaster declaration for the State of Illinois (FEMA-4116-DR), dated May 10, 2013, and...

78 FR 32412 - Illinois; Amendment No. 1 to Notice of a Major Disaster Declaration

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2013-05-30

... Island, Schuyler, Stark, Tazewell, and Woodford Counties for Individual Assistance. The following Catalog... Declaration AGENCY: Federal Emergency Management Agency, DHS. ACTION: Notice. SUMMARY: This notice amends the notice of a major disaster declaration for the State of Illinois (FEMA-4116-DR), dated May 10, 2013, and...

76 FR 66077 - Pennsylvania; Amendment No. 2 to Notice of a Major Disaster Declaration

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-25

.... FEMA-4030-DR; Docket ID FEMA-2011-0001] Pennsylvania; Amendment No. 2 to Notice of a Major Disaster... notice of a major disaster declaration for the Commonwealth of Pennsylvania (FEMA-4030-DR), dated... disaster declaration for the Commonwealth of Pennsylvania is hereby amended to include the Public...