46 CFR 97.40-10 - Draft marks and draft indicating systems.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 4 2011-10-01 2011-10-01 false Draft marks and draft indicating systems. 97.40-10... VESSELS OPERATIONS Markings on Vessels § 97.40-10 Draft marks and draft indicating systems. (a) All vessels must have draft marks plainly and legibly visible upon the stem and upon the sternpost or...

46 CFR 196.40-10 - Draft marks and draft indicating systems.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 7 2010-10-01 2010-10-01 false Draft marks and draft indicating systems. 196.40-10... VESSELS OPERATIONS Markings on Vessels § 196.40-10 Draft marks and draft indicating systems. (a) All vessels must have draft marks plainly and legibly visible upon the stem and upon the sternpost or...

46 CFR 196.40-10 - Draft marks and draft indicating systems.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 46 Shipping 7 2014-10-01 2014-10-01 false Draft marks and draft indicating systems. 196.40-10... VESSELS OPERATIONS Markings on Vessels § 196.40-10 Draft marks and draft indicating systems. (a) All vessels must have draft marks plainly and legibly visible upon the stem and upon the sternpost or...

Three Dimensional Shallow Water Adaptive Hydraulics (ADH-SW3): Waterborne Vessels

DTIC Science & Technology

2015-10-01

Type Value Description 1 char CBOW Card type 2 int > 0 Vessel number 3 real # Ratio of vessel bow to vessel draft CSTR FRACTION OF DRAFT...APPLIED TO PSTR Field Type Value Description 1 char CSTR Card type 2 int > 0 Vessel number 3 real # Ratio of vessel stern to vessel draft PROP

46 CFR 131.510 - Draft and loadline markings.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 4 2011-10-01 2011-10-01 false Draft and loadline markings. 131.510 Section 131.510..., Drills, and Inspections § 131.510 Draft and loadline markings. (a) The master of each vessel on an ocean or coastwise voyage shall enter in the vessel's logbook the drafts of the vessel, forward and aft...

46 CFR 131.510 - Draft and loadline markings.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 4 2010-10-01 2010-10-01 false Draft and loadline markings. 131.510 Section 131.510..., Drills, and Inspections § 131.510 Draft and loadline markings. (a) The master of each vessel on an ocean or coastwise voyage shall enter in the vessel's logbook the drafts of the vessel, forward and aft...

46 CFR 131.510 - Draft and loadline markings.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 46 Shipping 4 2013-10-01 2013-10-01 false Draft and loadline markings. 131.510 Section 131.510..., Drills, and Inspections § 131.510 Draft and loadline markings. (a) The master of each vessel on an ocean or coastwise voyage shall enter in the vessel's logbook the drafts of the vessel, forward and aft...

46 CFR 78.50-10 - Draft marks and draft indicating systems.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 46 Shipping 3 2013-10-01 2013-10-01 false Draft marks and draft indicating systems. 78.50-10... OPERATIONS Markings on Vessels § 78.50-10 Draft marks and draft indicating systems. (a) All vessels must have draft marks plainly and legibly visible upon the stem and upon the sternpost or rudderpost or any place...

46 CFR 78.50-10 - Draft marks and draft indicating systems.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 3 2010-10-01 2010-10-01 false Draft marks and draft indicating systems. 78.50-10... OPERATIONS Markings on Vessels § 78.50-10 Draft marks and draft indicating systems. (a) All vessels must have draft marks plainly and legibly visible upon the stem and upon the sternpost or rudderpost or any place...

46 CFR 78.50-10 - Draft marks and draft indicating systems.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 46 Shipping 3 2014-10-01 2014-10-01 false Draft marks and draft indicating systems. 78.50-10... OPERATIONS Markings on Vessels § 78.50-10 Draft marks and draft indicating systems. (a) All vessels must have draft marks plainly and legibly visible upon the stem and upon the sternpost or rudderpost or any place...

46 CFR 78.50-10 - Draft marks and draft indicating systems.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 46 Shipping 3 2012-10-01 2012-10-01 false Draft marks and draft indicating systems. 78.50-10... OPERATIONS Markings on Vessels § 78.50-10 Draft marks and draft indicating systems. (a) All vessels must have draft marks plainly and legibly visible upon the stem and upon the sternpost or rudderpost or any place...

46 CFR 78.50-10 - Draft marks and draft indicating systems.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 3 2011-10-01 2011-10-01 false Draft marks and draft indicating systems. 78.50-10... OPERATIONS Markings on Vessels § 78.50-10 Draft marks and draft indicating systems. (a) All vessels must have draft marks plainly and legibly visible upon the stem and upon the sternpost or rudderpost or any place...

46 CFR 131.220 - Drafts.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 46 Shipping 4 2012-10-01 2012-10-01 false Drafts. 131.220 Section 131.220 Shipping COAST GUARD... Drafts. (a) Each vessel must have the drafts of the vessel plainly and legibly marked upon the stem and... easy observance. The bottom of each mark must indicate the draft. (b) Each draft must be taken from the...

46 CFR 131.220 - Drafts.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 4 2010-10-01 2010-10-01 false Drafts. 131.220 Section 131.220 Shipping COAST GUARD... Drafts. (a) Each vessel must have the drafts of the vessel plainly and legibly marked upon the stem and... easy observance. The bottom of each mark must indicate the draft. (b) Each draft must be taken from the...

46 CFR 131.220 - Drafts.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 46 Shipping 4 2013-10-01 2013-10-01 false Drafts. 131.220 Section 131.220 Shipping COAST GUARD... Drafts. (a) Each vessel must have the drafts of the vessel plainly and legibly marked upon the stem and... easy observance. The bottom of each mark must indicate the draft. (b) Each draft must be taken from the...

46 CFR 131.220 - Drafts.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 4 2011-10-01 2011-10-01 false Drafts. 131.220 Section 131.220 Shipping COAST GUARD... Drafts. (a) Each vessel must have the drafts of the vessel plainly and legibly marked upon the stem and... easy observance. The bottom of each mark must indicate the draft. (b) Each draft must be taken from the...

46 CFR 131.220 - Drafts.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 46 Shipping 4 2014-10-01 2014-10-01 false Drafts. 131.220 Section 131.220 Shipping COAST GUARD... Drafts. (a) Each vessel must have the drafts of the vessel plainly and legibly marked upon the stem and... easy observance. The bottom of each mark must indicate the draft. (b) Each draft must be taken from the...

The economic implications of changing regulations for deep sea fishing under the European Common Fisheries Policy: UK case study.

PubMed

Mangi, Stephen C; Kenny, Andrew; Readdy, Lisa; Posen, Paulette; Ribeiro-Santos, Ana; Neat, Francis C; Burns, Finlay

2016-08-15

Economic impact assessment methodology was applied to UK fisheries data to better understand the implications of European Commission proposal for regulations to fishing for deep-sea stocks in the North-East Atlantic (EC COM 371 Final 2012) under the Common Fisheries Policy (CFP). The aim was to inform the on-going debate to develop the EC proposal, and to assist the UK fishing industry and Government in evaluating the most effective options to manage deep sea fish stocks. Results indicate that enforcing the EC proposal as originally drafted results in a number of implications for the UK fleet. Because of the proposed changes to the list of species defined as being deep sea species, and a new definition of what constitutes a vessel targeting deep sea species, a total of 695 active UK fishing vessels would need a permit to fish for deep sea species. However, due to existing and capped capacity limits many vessels would potentially not be able to obtain such a permit. The economic impact of these changes from the status quo reveals that in the short term, landings would decrease by 6540 tonnes, reducing gross value added by £3.3 million. Alternative options were also assessed that provide mitigation measures to offset the impacts of the proposed regulations whilst at the same time providing more effective protection of deep sea Vulnerable Marine Ecosystems (VMEs). The options include setting a 400m depth rule that identifies a depth beyond which vessels would potentially be classified as fishing for deep sea species and designating 'core areas' for deep sea fishing at depths>400m to minimise the risk of further impacts of bottom fishing gear on deep sea habitats. Applying a 400m depth limit and 'core fishing' area approach deeper than 400m, the impact of the EC proposal would essentially be reduced to zero, that is, on average no vessels (using the status quo capacity baseline) would be impacted by the proposal. Copyright © 2016 Elsevier B.V. All rights reserved.

Forest-Product Imports and Exports Via the Great Lakes-St. Lawrence Seaway Through Upper Lakes Ports

Treesearch

Eugene M. Carpenter

1966-01-01

The expanded Great Lakes-St. Lawrence Seaway system was opened in the early spring of 1959, and for the first time deep-draft ocean-going vessels could visit inland Great Lakes ports. In 1963 the Station published a Research Note reporting what effect this expansion may have had on the volume of forest products moving through Minnesota, Wisconsin, and Michigan ports;...

Management of Endurance Risk Factors: A Guide for Deep Draft Vessels

DTIC Science & Technology

2001-02-01

Poor diet (frequent fried foods, high fat and sugar content, frequent caffeine consumption) • High workload (high physical and/or mental effort...Appendix A) q 8. Poor diet (menu includes frequent fried foods, high fat and sugar content, frequent caffeine consumption; see Section II-4, and II...into glucose (or sugar ), amino acids, and fatty acids. Cells throughout the body then process these compounds to make energy or ATP

46 CFR 196.15-5 - Drafts.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 46 Shipping 7 2012-10-01 2012-10-01 false Drafts. 196.15-5 Section 196.15-5 Shipping COAST GUARD... Inspections § 196.15-5 Drafts. (a) The master of every vessel on an ocean, coastwise, or Great Lakes voyage shall enter the drafts of the vessel, forward and aft, in the official logbook when leaving port. (b) On...

46 CFR 196.15-5 - Drafts.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 46 Shipping 7 2014-10-01 2014-10-01 false Drafts. 196.15-5 Section 196.15-5 Shipping COAST GUARD... Inspections § 196.15-5 Drafts. (a) The master of every vessel on an ocean, coastwise, or Great Lakes voyage shall enter the drafts of the vessel, forward and aft, in the official logbook when leaving port. (b) On...

46 CFR 196.15-5 - Drafts.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 7 2011-10-01 2011-10-01 false Drafts. 196.15-5 Section 196.15-5 Shipping COAST GUARD... Inspections § 196.15-5 Drafts. (a) The master of every vessel on an ocean, coastwise, or Great Lakes voyage shall enter the drafts of the vessel, forward and aft, in the official logbook when leaving port. (b) On...

46 CFR 196.15-5 - Drafts.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 46 Shipping 7 2013-10-01 2013-10-01 false Drafts. 196.15-5 Section 196.15-5 Shipping COAST GUARD... Inspections § 196.15-5 Drafts. (a) The master of every vessel on an ocean, coastwise, or Great Lakes voyage shall enter the drafts of the vessel, forward and aft, in the official logbook when leaving port. (b) On...

46 CFR 196.15-5 - Drafts.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 7 2010-10-01 2010-10-01 false Drafts. 196.15-5 Section 196.15-5 Shipping COAST GUARD... Inspections § 196.15-5 Drafts. (a) The master of every vessel on an ocean, coastwise, or Great Lakes voyage shall enter the drafts of the vessel, forward and aft, in the official logbook when leaving port. (b) On...

46 CFR 78.17-20 - Drafts and load line markings.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 46 Shipping 3 2012-10-01 2012-10-01 false Drafts and load line markings. 78.17-20 Section 78.17-20..., Drills, and Inspections § 78.17-20 Drafts and load line markings. (a) The master of every vessel on an ocean, coastwise, or Great Lakes voyage shall enter the drafts of the vessel, forward and aft, in the...

46 CFR 97.15-5 - Drafts and load line markings.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 46 Shipping 4 2014-10-01 2014-10-01 false Drafts and load line markings. 97.15-5 Section 97.15-5... OPERATIONS Tests, Drills, and Inspections § 97.15-5 Drafts and load line markings. (a) The master of every vessel on an ocean, coastwise, or Great Lakes voyage shall enter the drafts of the vessel, forward and...

46 CFR 78.17-20 - Drafts and load line markings.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 3 2011-10-01 2011-10-01 false Drafts and load line markings. 78.17-20 Section 78.17-20..., Drills, and Inspections § 78.17-20 Drafts and load line markings. (a) The master of every vessel on an ocean, coastwise, or Great Lakes voyage shall enter the drafts of the vessel, forward and aft, in the...

46 CFR 78.17-20 - Drafts and load line markings.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 46 Shipping 3 2013-10-01 2013-10-01 false Drafts and load line markings. 78.17-20 Section 78.17-20..., Drills, and Inspections § 78.17-20 Drafts and load line markings. (a) The master of every vessel on an ocean, coastwise, or Great Lakes voyage shall enter the drafts of the vessel, forward and aft, in the...

46 CFR 78.17-20 - Drafts and load line markings.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 46 Shipping 3 2014-10-01 2014-10-01 false Drafts and load line markings. 78.17-20 Section 78.17-20..., Drills, and Inspections § 78.17-20 Drafts and load line markings. (a) The master of every vessel on an ocean, coastwise, or Great Lakes voyage shall enter the drafts of the vessel, forward and aft, in the...

46 CFR 97.15-5 - Drafts and load line markings.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 4 2010-10-01 2010-10-01 false Drafts and load line markings. 97.15-5 Section 97.15-5... OPERATIONS Tests, Drills, and Inspections § 97.15-5 Drafts and load line markings. (a) The master of every vessel on an ocean, coastwise, or Great Lakes voyage shall enter the drafts of the vessel, forward and...

46 CFR 97.15-5 - Drafts and load line markings.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 4 2011-10-01 2011-10-01 false Drafts and load line markings. 97.15-5 Section 97.15-5... OPERATIONS Tests, Drills, and Inspections § 97.15-5 Drafts and load line markings. (a) The master of every vessel on an ocean, coastwise, or Great Lakes voyage shall enter the drafts of the vessel, forward and...

46 CFR 97.15-5 - Drafts and load line markings.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 46 Shipping 4 2012-10-01 2012-10-01 false Drafts and load line markings. 97.15-5 Section 97.15-5... OPERATIONS Tests, Drills, and Inspections § 97.15-5 Drafts and load line markings. (a) The master of every vessel on an ocean, coastwise, or Great Lakes voyage shall enter the drafts of the vessel, forward and...

46 CFR 97.15-5 - Drafts and load line markings.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 46 Shipping 4 2013-10-01 2013-10-01 false Drafts and load line markings. 97.15-5 Section 97.15-5... OPERATIONS Tests, Drills, and Inspections § 97.15-5 Drafts and load line markings. (a) The master of every vessel on an ocean, coastwise, or Great Lakes voyage shall enter the drafts of the vessel, forward and...

Modeling Vessel-Generated Currents and Bed Shear Stresses

DTIC Science & Technology

2008-06-01

Vessel 1, the fraction of the draft applied over PBOW is 0.95. CSTR 1 0.95 For Vessel 1, the fraction of the draft applied over PSTR is 0.95...vessel draft is 0.95. CSTR 2 0.95 For Vessel 2, the ratio of the stern length to the vessel length is 0.95. PROP 2 1 2.74 6 52 5 The propellers...PBOW 1 0.1 PSTR 1 0.1 CBOW 1 0.95 CSTR 1 0.95 PROP 1 2 2.74 6 52.5 SDEF 1 1 0 -3080.0 -1.5 2.9 FDEF 2 1 -6955.0 -1.5 2.9 DRFT 2 2.74 BLEN 2

46 CFR 131.510 - Draft and loadline markings.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 46 Shipping 4 2012-10-01 2012-10-01 false Draft and loadline markings. 131.510 Section 131.510 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OFFSHORE SUPPLY VESSELS OPERATIONS Tests, Drills, and Inspections § 131.510 Draft and loadline markings. (a) The master of each vessel on an ocean...

46 CFR 169.755 - Draft marks and draft indicating systems.

Code of Federal Regulations, 2012 CFR

2012-10-01

... Section 169.755 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) NAUTICAL SCHOOLS SAILING SCHOOL VESSELS Vessel Control, Miscellaneous Systems, and Equipment Markings § 169.755 Draft marks and... projections of the marks onto a vertical plane are of uniform height equal to the vertical spacing between...

46 CFR 169.755 - Draft marks and draft indicating systems.

Code of Federal Regulations, 2013 CFR

2013-10-01

... Section 169.755 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) NAUTICAL SCHOOLS SAILING SCHOOL VESSELS Vessel Control, Miscellaneous Systems, and Equipment Markings § 169.755 Draft marks and... projections of the marks onto a vertical plane are of uniform height equal to the vertical spacing between...

46 CFR 169.755 - Draft marks and draft indicating systems.

Code of Federal Regulations, 2011 CFR

2011-10-01

... Section 169.755 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) NAUTICAL SCHOOLS SAILING SCHOOL VESSELS Vessel Control, Miscellaneous Systems, and Equipment Markings § 169.755 Draft marks and... projections of the marks onto a vertical plane are of uniform height equal to the vertical spacing between...

46 CFR 169.755 - Draft marks and draft indicating systems.

Code of Federal Regulations, 2014 CFR

2014-10-01

... Section 169.755 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) NAUTICAL SCHOOLS SAILING SCHOOL VESSELS Vessel Control, Miscellaneous Systems, and Equipment Markings § 169.755 Draft marks and... projections of the marks onto a vertical plane are of uniform height equal to the vertical spacing between...

46 CFR 169.755 - Draft marks and draft indicating systems.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Section 169.755 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) NAUTICAL SCHOOLS SAILING SCHOOL VESSELS Vessel Control, Miscellaneous Systems, and Equipment Markings § 169.755 Draft marks and... projections of the marks onto a vertical plane are of uniform height equal to the vertical spacing between...

46 CFR 131.510 - Draft and loadline markings.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 46 Shipping 4 2014-10-01 2014-10-01 false Draft and loadline markings. 131.510 Section 131.510 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OFFSHORE SUPPLY VESSELS OPERATIONS Tests, Drills, and Inspections § 131.510 Draft and loadline markings. (a) The master of each vessel on an ocean...

77 FR 16270 - Updated Aging Management Criteria for Reactor Vessel Internal Components of Pressurized Water...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-20

... NUCLEAR REGULATORY COMMISSION [NRC-2012-0070] Updated Aging Management Criteria for Reactor Vessel Internal Components of Pressurized Water Reactors AGENCY: Nuclear Regulatory Commission. ACTION: Draft..., ``Updated Aging Management Criteria for PWR Reactor Vessel Internal Components.'' This draft LR-ISG revises...

33 CFR 148.215 - What if a port has plans for a deep draft channel and harbor?

Code of Federal Regulations, 2013 CFR

2013-07-01

... deep draft channel and harbor? 148.215 Section 148.215 Navigation and Navigable Waters COAST GUARD... General § 148.215 What if a port has plans for a deep draft channel and harbor? (a) If a State port will... draft channel and harbor, a representative of the port may request a determination under 33 U.S.C. 1503...

33 CFR 117.585 - Acushnet River.

Code of Federal Regulations, 2010 CFR

2010-07-01

... vessels whose draft exceeds 15 feet, for vessels owned or operated by the U.S. Government, the State of Massachusetts, or by local authorities. (c) Each opening of the draw, from the time vehicular traffic flow is stopped until the flow resumes, shall not exceed 15 minutes except for vessels whose draft exceeds 15 feet...

33 CFR 148.215 - What if a port has plans for a deep draft channel and harbor?

Code of Federal Regulations, 2010 CFR

2010-07-01

... General § 148.215 What if a port has plans for a deep draft channel and harbor? (a) If a State port will be directly connected by pipeline to a proposed deepwater port, and has existing plans for a deep... deep draft channel and harbor? 148.215 Section 148.215 Navigation and Navigable Waters COAST GUARD...

Investigation into Deep-Draft Vessel Berthing Problems at Selected U. S. Naval Facilities.

DTIC Science & Technology

1980-10-01

AOR I WICHITA Alameda, CA 1-24-75 AOR 2 MILWAUKEE Norfolk, VA 1-01-74 AOR 3 KANSAS CITY Alameda, CA 2-16-74 AOR 4 SAVANNAH Norfolk, VA 12-05-70 AOR...auger-cutter assembly dislodges and delivers the material to the pump suction intake. The slurry is pumped to a pipeline for transmission to a remote...complete loss of control of the course steered. Large current eddies having the same effect are found in the vicinity of the foundation piers of the San

46 CFR 78.17-20 - Drafts and load line markings.

Code of Federal Regulations, 2010 CFR

2010-10-01

... surface of the water in which the vessel is floating. (2) When an allowance for draft is made for density of the water in which the vessel is floating, this density is to be noted in the official logbook. ...

Bedrock knobs, San Francisco Bay: Do navigation hazards outweigh other environment problems?

USGS Publications Warehouse

Carlson, P.R.; Chin, J.L.; Wong, F.L.

2000-01-01

Three bedrock knobs (Arch, Harding, and Shag rocks) rise above the unconsolidated sediment of central San Francisco Bay to a water depth of less than -12 m (<-39.4 ft MLLW). These rocks are within the westbound vessel traffic area, and the northernmost, Harding Rock, is ~300 m (984 ft) from the two-way deep water traffic lane. The rocks pose a hazard to deep-draft vessels. Large ships with drafts deeper than -17 m (-55.8 ft) cross central San Francisco Bay bound for and returning from major port cities of the Bay estuary. Acoustic profiling data show that bedrock extends at a gentle to moderate slope away from the knobs. These data also show that two of the knobs, Harding and Shag, may be part of a bedrock ridge that extends to Alcatraz Island and perhaps southeast to Blossom Rock. The tops of these rocks should be lowered to a depth of -17 m (-55.8 ft), with a total volume of as much as 245,000 m3 (320,460 yd3), at an estimated cost of nearly 27 million dollars, to eliminate the possibility that a tanker would strike one and rupture. A resulting large oil spill would likely cost many times more than the 10 million dollars needed to clean up a small 1996 spill. If the rocks were removed, local habitat for striped bass and other game fish would be altered, with potential negative impact on sport fishing. Currently, public officials are studying the benefits to the Bay environment of lowering the rock knobs.

33 CFR 401.29 - Maximum draft.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 33 Navigation and Navigable Waters 3 2012-07-01 2012-07-01 false Maximum draft. 401.29 Section 401... TRANSPORTATION SEAWAY REGULATIONS AND RULES Regulations Seaway Navigation § 401.29 Maximum draft. (a) The draft...) The draft of a vessel shall not, in any case, exceed 79.2 dm or the maximum permissible draft...

33 CFR 401.29 - Maximum draft.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 33 Navigation and Navigable Waters 3 2011-07-01 2011-07-01 false Maximum draft. 401.29 Section 401... TRANSPORTATION SEAWAY REGULATIONS AND RULES Regulations Seaway Navigation § 401.29 Maximum draft. (a) The draft...) The draft of a vessel shall not, in any case, exceed 79.2 dm or the maximum permissible draft...

33 CFR 401.29 - Maximum draft.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Maximum draft. 401.29 Section 401... TRANSPORTATION SEAWAY REGULATIONS AND RULES Regulations Seaway Navigation § 401.29 Maximum draft. (a) The draft...) The draft of a vessel shall not, in any case, exceed 79.2 dm or the maximum permissible draft...

46 CFR 32.05-1 - Draft marks and draft indicating systems-TB/ALL.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 46 Shipping 1 2014-10-01 2014-10-01 false Draft marks and draft indicating systems-TB/ALL. 32.05-1..., MACHINERY, AND HULL REQUIREMENTS Markings § 32.05-1 Draft marks and draft indicating systems—TB/ALL. (a) All vessels must have draft marks plainly and legibly visible upon the stem and upon the sternpost or...

46 CFR 32.05-1 - Draft marks and draft indicating systems-TB/ALL.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 1 2011-10-01 2011-10-01 false Draft marks and draft indicating systems-TB/ALL. 32.05-1..., MACHINERY, AND HULL REQUIREMENTS Markings § 32.05-1 Draft marks and draft indicating systems—TB/ALL. (a) All vessels must have draft marks plainly and legibly visible upon the stem and upon the sternpost or...

46 CFR 32.05-1 - Draft marks and draft indicating systems-TB/ALL.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 1 2010-10-01 2010-10-01 false Draft marks and draft indicating systems-TB/ALL. 32.05-1..., MACHINERY, AND HULL REQUIREMENTS Markings § 32.05-1 Draft marks and draft indicating systems—TB/ALL. (a) All vessels must have draft marks plainly and legibly visible upon the stem and upon the sternpost or...

46 CFR 32.05-1 - Draft marks and draft indicating systems-TB/ALL.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 46 Shipping 1 2013-10-01 2013-10-01 false Draft marks and draft indicating systems-TB/ALL. 32.05-1..., MACHINERY, AND HULL REQUIREMENTS Markings § 32.05-1 Draft marks and draft indicating systems—TB/ALL. (a) All vessels must have draft marks plainly and legibly visible upon the stem and upon the sternpost or...

46 CFR 32.05-1 - Draft marks and draft indicating systems-TB/ALL.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 46 Shipping 1 2012-10-01 2012-10-01 false Draft marks and draft indicating systems-TB/ALL. 32.05-1..., MACHINERY, AND HULL REQUIREMENTS Markings § 32.05-1 Draft marks and draft indicating systems—TB/ALL. (a) All vessels must have draft marks plainly and legibly visible upon the stem and upon the sternpost or...

Draft Permit & Supporting Documentation for the Northeast Gateway Energy Bridge Deepwater Port, Federal Waters of Massachusetts Bay (Modification to Existing Permit LNG Regasification Vessel/DWP Project)

EPA Pesticide Factsheets

List of draft permit & supporting documentation for the Northeast Gateway Energy Bridge Deepwater Port, Federal Waters of Massachusetts Bay (Modification to Existing Permit LNG Regasification Vessel/DWP Project).

46 CFR 174.040 - Stability requirements: general.

Code of Federal Regulations, 2013 CFR

2013-10-01

... PERTAINING TO SPECIFIC VESSEL TYPES Special Rules Pertaining to Mobile Offshore Drilling Units § 174.040... draft for navigation, towing, or drilling afloat, or at a temporary draft when changing drafts. ...

46 CFR 174.040 - Stability requirements: general.

Code of Federal Regulations, 2010 CFR

2010-10-01

... PERTAINING TO SPECIFIC VESSEL TYPES Special Rules Pertaining to Mobile Offshore Drilling Units § 174.040... draft for navigation, towing, or drilling afloat, or at a temporary draft when changing drafts. ...

78 FR 77027 - Overhead Clearance (Air-Draft) Accidents

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-20

... No. USCG-2013-0466] Overhead Clearance (Air-Draft) Accidents AGENCY: Coast Guard, DHS. ACTION... clearance (air-draft) accidents. In its petition, which calls for vessel masters to be provided with accurate vertical air draft information, a maritime organization has described 16 overhead clearance...

33 CFR 401.29 - Maximum draft.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 33 Navigation and Navigable Waters 3 2014-07-01 2014-07-01 false Maximum draft. 401.29 Section 401... TRANSPORTATION SEAWAY REGULATIONS AND RULES Regulations Seaway Navigation § 401.29 Maximum draft. (a) Notwithstanding any provision herein, the loading of cargo, draft and speed of a vessel in transit shall be...

33 CFR 401.29 - Maximum draft.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 33 Navigation and Navigable Waters 3 2013-07-01 2013-07-01 false Maximum draft. 401.29 Section 401... TRANSPORTATION SEAWAY REGULATIONS AND RULES Regulations Seaway Navigation § 401.29 Maximum draft. (a) Notwithstanding any provision herein, the loading of cargo, draft and speed of a vessel in transit shall be...

78 FR 9709 - Draft Guidance Regarding Voluntary Inspection of Vessels for Compliance With the Maritime Labour...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-11

... availability of a draft Navigation and Vessel Inspection Circular (NVIC) that sets forth the Coast Guard's... guidance to the maritime industry, Coast Guard marine inspectors, and other affected parties on how the... and Coast Guard marine inspectors on how the Coast Guard intends to implement this new voluntary...

46 CFR 169.840 - Verification of vessel compliance with applicable stability requirements.

Code of Federal Regulations, 2011 CFR

2011-10-01

... that the vessel complies with all applicable stability requirements in the vessel's trim and stability... stability requirements the vessel's draft, trim, and stability must be determined as necessary and any...

46 CFR 196.15-7 - Verification of vessel compliance with applicable stability requirements.

Code of Federal Regulations, 2010 CFR

2010-10-01

... the vessel complies with all applicable stability requirements in the vessel's trim and stability book... requirements the vessel's draft, trim, and stability must be determined as necessary and any stability...

46 CFR 167.65-42 - Verification of vessel compliance with applicable stability requirements.

Code of Federal Regulations, 2011 CFR

2011-10-01

... that the vessel complies with all applicable stability requirements in the vessel's trim and stability... stability requirements the vessel's draft, trim, and stability must be determined as necessary and any...

46 CFR 169.840 - Verification of vessel compliance with applicable stability requirements.

Code of Federal Regulations, 2010 CFR

2010-10-01

... that the vessel complies with all applicable stability requirements in the vessel's trim and stability... stability requirements the vessel's draft, trim, and stability must be determined as necessary and any...

46 CFR 167.65-42 - Verification of vessel compliance with applicable stability requirements.

Code of Federal Regulations, 2010 CFR

2010-10-01

... that the vessel complies with all applicable stability requirements in the vessel's trim and stability... stability requirements the vessel's draft, trim, and stability must be determined as necessary and any...

46 CFR 196.15-7 - Verification of vessel compliance with applicable stability requirements.

Code of Federal Regulations, 2011 CFR

2011-10-01

... the vessel complies with all applicable stability requirements in the vessel's trim and stability book... requirements the vessel's draft, trim, and stability must be determined as necessary and any stability...

46 CFR 35.20-5 - Draft of tankships-T/OC.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 1 2011-10-01 2011-10-01 false Draft of tankships-T/OC. 35.20-5 Section 35.20-5 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY TANK VESSELS OPERATIONS Navigation § 35.20-5 Draft of tankships—T/OC. The master of every tankship shall, whenever leaving port, enter the maximum draft of his...

46 CFR 35.20-5 - Draft of tankships-T/OC.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 1 2010-10-01 2010-10-01 false Draft of tankships-T/OC. 35.20-5 Section 35.20-5 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY TANK VESSELS OPERATIONS Navigation § 35.20-5 Draft of tankships—T/OC. The master of every tankship shall, whenever leaving port, enter the maximum draft of his...

46 CFR 35.20-5 - Draft of tankships-T/OC.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 46 Shipping 1 2014-10-01 2014-10-01 false Draft of tankships-T/OC. 35.20-5 Section 35.20-5 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY TANK VESSELS OPERATIONS Navigation § 35.20-5 Draft of tankships—T/OC. The master of every tankship shall, whenever leaving port, enter the maximum draft of his...

46 CFR 35.20-5 - Draft of tankships-T/OC.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 46 Shipping 1 2012-10-01 2012-10-01 false Draft of tankships-T/OC. 35.20-5 Section 35.20-5 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY TANK VESSELS OPERATIONS Navigation § 35.20-5 Draft of tankships—T/OC. The master of every tankship shall, whenever leaving port, enter the maximum draft of his...

46 CFR 35.20-5 - Draft of tankships-T/OC.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 46 Shipping 1 2013-10-01 2013-10-01 false Draft of tankships-T/OC. 35.20-5 Section 35.20-5 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY TANK VESSELS OPERATIONS Navigation § 35.20-5 Draft of tankships—T/OC. The master of every tankship shall, whenever leaving port, enter the maximum draft of his...

Deep-Draft Navigation User Charges : Recovery Options and Impacts

DOT National Transportation Integrated Search

1977-08-01

Alternative cost recovery options for Federal deep-draft navigation expenditures are investigated and the impacts of user charges on waterborne trades and commodity traffic, both foreign and domestic (Great Lakes and coastwise), are assessed. In addi...

Assessing risk of draft survey by AHP method

NASA Astrophysics Data System (ADS)

Xu, Guangcheng; Zhao, Kuimin; Zuo, Zhaoying; Liu, Gang; Jian, Binguo; Lin, Yan; Fan, Yukun; Wang, Fei

2018-04-01

The paper assesses the risks of vessel floating in the seawater for draft survey by using the analytic hierarchy process. On this basis, the paper established draft survey risk index from the view of draft reading, ballast water, fresh water, and calculation process and so on. Then the paper proposes the method to deal with risk assessment using one concrete sample.

33 CFR 157.10b - Segregated ballast tanks, dedicated clean ballast tanks, and special ballast arrangements for...

Code of Federal Regulations, 2010 CFR

2010-07-01

... capability of meeting each of the following: (1) The molded draft amidship (dm), in meters, without taking...: dm=2.00+0.020L for vessels of 150 meters or more in length dm=1.25+0.025L for vessels less than 150 meters in length (2) The drafts, in meters, at the forward and after perpendiculars must correspond to...

46 CFR 35.20-7 - Verification of vessel compliance with applicable stability requirements-TB/ALL.

Code of Federal Regulations, 2011 CFR

2011-10-01

... the vessels's trim and stability book, stability letter, Certificate of Inspection, and Load Line.... (b) When determining compliance with applicable stability requirements the vessel's draft, trim, and...

46 CFR 35.20-7 - Verification of vessel compliance with applicable stability requirements-TB/ALL.

Code of Federal Regulations, 2010 CFR

2010-10-01

... the vessels's trim and stability book, stability letter, Certificate of Inspection, and Load Line.... (b) When determining compliance with applicable stability requirements the vessel's draft, trim, and...

46 CFR 97.15-7 - Verification of vessel compliance with applicable stability requirements.

Code of Federal Regulations, 2011 CFR

2011-10-01

... applicable stability requirements in the vessel's trim and stability book, stability letter, Certificate of... the vessel's draft, trim, and stability must be determined as necessary. (c) If a log book is required...

46 CFR 97.15-7 - Verification of vessel compliance with applicable stability requirements.

Code of Federal Regulations, 2010 CFR

2010-10-01

... applicable stability requirements in the vessel's trim and stability book, stability letter, Certificate of... the vessel's draft, trim, and stability must be determined as necessary. (c) If a log book is required...

33 CFR 148.215 - What if a port has plans for a deep draft channel and harbor?

Code of Federal Regulations, 2012 CFR

2012-07-01

... that the port has an active study by the Secretary of the Army for the construction of a deep draft... in tax revenues; (vii) Environmental and social impacts of the project on the local and regional...

33 CFR 148.215 - What if a port has plans for a deep draft channel and harbor?

Code of Federal Regulations, 2011 CFR

2011-07-01

... that the port has an active study by the Secretary of the Army for the construction of a deep draft... in tax revenues; (vii) Environmental and social impacts of the project on the local and regional...

A summary of chemical and biological testing of proposed disposal of sediment from Richmond Harbor relative to the Deep Off-Shelf Reference Area, the Bay Farm Borrow Area, and the Alcatraz Environs Reference Area

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mayhew, H.L.; Karle, L.M.; Gruendell, B.D.

The US Army Corps of Engineers was authorized to dredge Richmond Harbor to accomodate large, deep-draft vessels. An ecological evaluation of the Harbor sediments was performed describing the physical characteristics, toxic substances, effects on aquatic organisms,and potential for bioaccumulation of chemical contaminants. The objective of this report is to compare the sediment chemistry, acute toxicity, and bioaccumulation results of the Richmond Harbor sediments to each of the reference areas; i.e., the Deep Off-Shelf Reference Area, the Bay Farm Borrow Area, and the Alcatraz Environs Reference Area. This report will enable the US Army Corps of Engineers to determine whether disposalmore » at a reference area is appropriate for all or part of the dredged material from Richmond Harbor. Chemical analyses were performed on 30 sediment samples; 28 of those samples were then combined to form 7 composites. The seven composites plus sediment from two additional stations received both chemical and biological evaluations.« less

46 CFR 32.56-45 - Draft stops-T/ALL.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 1 2011-10-01 2011-10-01 false Draft stops-T/ALL. 32.56-45 Section 32.56-45 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY TANK VESSELS SPECIAL EQUIPMENT, MACHINERY, AND HULL....56-45 Draft stops—T/ALL. (a) Where ceilings or linings are fitted in accommodation, service, or...

46 CFR 32.56-45 - Draft stops-T/ALL.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 1 2010-10-01 2010-10-01 false Draft stops-T/ALL. 32.56-45 Section 32.56-45 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY TANK VESSELS SPECIAL EQUIPMENT, MACHINERY, AND HULL....56-45 Draft stops—T/ALL. (a) Where ceilings or linings are fitted in accommodation, service, or...

Draft Genome Sequence of Deep-Sea Alteromonas sp. Strain V450 Isolated from the Marine Sponge Leiodermatium sp.

PubMed Central

Barrett, Nolan H.; McCarthy, Peter J.

2017-01-01

ABSTRACT The proteobacterium Alteromonas sp. strain V450 was isolated from the Atlantic deep-sea sponge Leiodermatium sp. Here, we report the draft genome sequence of this strain, with a genome size of approx. 4.39 Mb and a G+C content of 44.01%. The results will aid deep-sea microbial ecology, evolution, and sponge-microbe association studies. PMID:28153886

The deep lymphatic anatomy of the hand.

PubMed

Ma, Chuan-Xiang; Pan, Wei-Ren; Liu, Zhi-An; Zeng, Fan-Qiang; Qiu, Zhi-Qiang

2018-07-01

The deep lymphatic anatomy of the hand still remains the least described in medical literature. Eight hands were harvested from four nonembalmed human cadavers amputated above the wrist. A small amount of 6% hydrogen peroxide was employed to detect the lymphatic vessels around the superficial and deep palmar vascular arches, in webs from the index to little fingers, the thenar and hypothenar areas. A 30-gauge needle was inserted into the vessels and injected with a barium sulphate compound. Each specimen was dissected, photographed and radiographed to demonstrate deep lymphatic distribution of the hand. Five groups of deep collecting lymph vessels were found in the hand: superficial palmar arch lymph vessel (SPALV); deep palmar arch lymph vessel (DPALV); thenar lymph vessel (TLV); hypothenar lymph vessel (HTLV); deep finger web lymph vessel (DFWLV). Each group of vessels drained in different directions first, then all turned and ran towards the wrist in different layers. The deep lymphatic drainage of the hand has been presented. The results will provide an anatomical basis for clinical management, educational reference and scientific research. Copyright © 2018 Elsevier GmbH. All rights reserved.

Draft Genome Sequence of Deep-Sea Alteromonas sp. Strain V450 Isolated from the Marine Sponge Leiodermatium sp.

PubMed

Wang, Guojun; Barrett, Nolan H; McCarthy, Peter J

2017-02-02

The proteobacterium Alteromonas sp. strain V450 was isolated from the Atlantic deep-sea sponge Leiodermatium sp. Here, we report the draft genome sequence of this strain, with a genome size of approx. 4.39 Mb and a G+C content of 44.01%. The results will aid deep-sea microbial ecology, evolution, and sponge-microbe association studies. Copyright © 2017 Wang et al.

75 FR 51755 - New England Fishery Management Council; Public Hearing

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-23

... comments on proposals to be included in the Draft Amendment 3 to the Deep Sea Red Crab Fishery Management... to [email protected] with ``Comments on Red Crab Draft Amendment 3'' in the subject line... Council proposes to take action to amend the Deep Sea Red Crab Fishery Management Plan (FMP) and to...

46 CFR 169.807 - Notice of casualty.

Code of Federal Regulations, 2014 CFR

2014-10-01

... the vessel's seaworthiness or fitness for service or route, including but not limited to fire... of the vessel involved, the name of the vessel's owner or agent, nature, location and circumstances..., navigation charts, navigation work books, compass deviation cards, gyrocompass records, record of draft, aids...

46 CFR 169.807 - Notice of casualty.

Code of Federal Regulations, 2013 CFR

2013-10-01

... the vessel's seaworthiness or fitness for service or route, including but not limited to fire... of the vessel involved, the name of the vessel's owner or agent, nature, location and circumstances..., navigation charts, navigation work books, compass deviation cards, gyrocompass records, record of draft, aids...

46 CFR 169.807 - Notice of casualty.

Code of Federal Regulations, 2012 CFR

2012-10-01

... the vessel's seaworthiness or fitness for service or route, including but not limited to fire... of the vessel involved, the name of the vessel's owner or agent, nature, location and circumstances..., navigation charts, navigation work books, compass deviation cards, gyrocompass records, record of draft, aids...

75 FR 3746 - Draft Program Comment for the Department of the Navy for the Disposition of Historic Vessels

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-22

... less than fifty years. Because naval vessels have a limited useful life, the Chief of Naval Operations undertakes a Ship Disposition Review (SDR) each year to determine whether any vessels should be... service for typically less than fifty years. Because naval vessels have a limited useful life, the Chief...

77 FR 23513 - Updated Aging Management Criteria for Reactor Vessel Internal Components of Pressurized Water...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-19

... NUCLEAR REGULATORY COMMISSION [NRC-2012-0070] Updated Aging Management Criteria for Reactor Vessel Internal Components of Pressurized Water Reactors AGENCY: Nuclear Regulatory Commission. ACTION: Draft...-ISG), LR-ISG-2011-04, ``Updated Aging Management Criteria for PWR Reactor Vessel Internal Components...

Perforating and deep lymphatic vessels in the knee region: an anatomical study and clinical implications.

PubMed

Pan, Wei-Ren; Zeng, Fan-Qiang; Wang, De-Guang; Qiu, Zhi-Qiang

2017-05-01

To determine the relationship between the perforating and deep lymphatic vessels in the knee region for clinical implications. Four lower limbs from two unembalmed human cadavers were used. Under a surgical microscope, 6% hydrogen peroxide was employed to detect lymph vessels accompanying the small saphenous vein, anterior tibial, posterior tibial and fibular blood vessels all commencing from distal ends of specimens. Each lymphatic vessel was inserted by a 30-gauge needle and injected with a barium sulphate mixture. Each specimen was dissected, radiographed and photographed to determine the perforating and deep lymphatic vessels in the region. A perforating lymph vessel was observed in the popliteal fossa of each specimen. It arose from the superficial popliteal lymph node and terminated in the deep popliteal lymph node. The anterior tibial, posterior tibial and peroneal lymph vessels were discovered in the region travelling with the corresponding vascular bundles. After penetrating the vascular aperture of the interosseous membrane between the tibia and fibula, the anterior tibial lymph vessel entered directly into the deep popliteal lymph node or converged to either the posterior tibial or fibular lymph vessel, before entering the node. The posterior tibial and peroneal lymph vessels entered the deep popliteal lymph node. The efferent lymph vessel of the deep popliteal lymph node travelled with the femoral vascular bundle. The perforating and deep lymphatic vessels in the knee region has been presented and discussed. The information advances our anatomical knowledge and the results will benefit clinical management. © 2017 Royal Australasian College of Surgeons.

Changing vessel routes could significantly reduce the cost of future offshore wind projects.

PubMed

Samoteskul, Kateryna; Firestone, Jeremy; Corbett, James; Callahan, John

2014-08-01

With the recent emphasis on offshore wind energy Coastal and Marine Spatial Planning (CMSP) has become one of the main frameworks used to plan and manage the increasingly complex web of ocean and coastal uses. As wind development becomes more prevalent, existing users of the ocean space, such as commercial shippers, will be compelled to share their historically open-access waters with these projects. Here, we demonstrate the utility of using cost-effectiveness analysis (CEA) to support siting decisions within a CMSP framework. In this study, we assume that large-scale offshore wind development will take place in the US Mid-Atlantic within the next decades. We then evaluate whether building projects nearshore or far from shore would be more cost-effective. Building projects nearshore is assumed to require rerouting of the commercial vessel traffic traveling between the US Mid-Atlantic ports by an average of 18.5 km per trip. We focus on less than 1500 transits by large deep-draft vessels. We estimate that over 29 years of the study, commercial shippers would incur an additional $0.2 billion (in 2012$) in direct and indirect costs. Building wind projects closer to shore where vessels used to transit would generate approximately $13.4 billion (in 2012$) in savings. Considering the large cost savings, modifying areas where vessels transit needs to be included in the portfolio of policies used to support the growth of the offshore wind industry in the US. Copyright © 2014 Elsevier Ltd. All rights reserved.

46 CFR 78.17-22 - Verification of vessel compliance with applicable stability requirements.

Code of Federal Regulations, 2010 CFR

2010-10-01

... with all applicable stability requirements in the vessel's trim and stability book, stability letter... draft, trim, and stability must be determined as necessary and any stability calculations made in...

46 CFR 78.17-22 - Verification of vessel compliance with applicable stability requirements.

Code of Federal Regulations, 2011 CFR

2011-10-01

... with all applicable stability requirements in the vessel's trim and stability book, stability letter... draft, trim, and stability must be determined as necessary and any stability calculations made in...

Draft genome of bagasse-degrading bacteria Bacillus aryabhattai GZ03 from deep sea water.

PubMed

Wen, Jian; Ren, Chong; Huang, Nan; Liu, Yang; Zeng, Runying

2015-02-01

Bacillus aryabhattai GZ03 was isolated from deep sea water of the South China Sea, which can produce glucose and fructose by degrading bagasse at 25 °C. Here we report the draft genome sequence of Bacillus aryabhattai GZ03. The data obtained revealed 37 contigs with genome size of 5,105,129 bp and G+C content of 38.09%. The draft genome of B. aryabhattai GZ03 may provide insights into the mechanism of microbial carbohydrate and lignocellulosic material degradation. Copyright © 2014 Elsevier B.V. All rights reserved.

76 FR 3646 - Safety Requirements and Manning Exemption Eligibility on Distant Water Tuna Fleet Vessels

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-20

...Pursuant to Section 904 of the 2010 Coast Guard Authorization Act, the Coast Guard announces the availability of a draft policy regarding distant water tuna fleet vessels manning exemption eligibility and safety requirements. We request your comments on the Safety Requirements and Manning Exemption Eligibility on Distant Water Tuna Fleet Vessels.

Draft Genome Sequence of Pseudomonas oceani DSM 100277T, a Deep-Sea Bacterium

PubMed Central

2018-01-01

ABSTRACT Pseudomonas oceani DSM 100277T was isolated from deep seawater in the Okinawa Trough at 1390 m. P. oceani belongs to the Pseudomonas pertucinogena group. Here, we report the draft genome sequence of P. oceani, which has an estimated size of 4.1 Mb and exhibits 3,790 coding sequences, with a G+C content of 59.94 mol%. PMID:29650573

41 CFR 102-37.230 - What must a letter of intent for obtaining surplus aircraft or vessels include?

Code of Federal Regulations, 2011 CFR

2011-01-01

..., name, class, size, displacement, length, beam, draft, lift capacity, and the hull or registry number... cannibalization process, how recovered parts are to be used, method of accounting for usable parts, disposition of... pilot(s) and where the vessel will be docked. If a vessel is requested for permanent docking on water or...

41 CFR 102-37.230 - What must a letter of intent for obtaining surplus aircraft or vessels include?

Code of Federal Regulations, 2012 CFR

2012-01-01

..., name, class, size, displacement, length, beam, draft, lift capacity, and the hull or registry number... cannibalization process, how recovered parts are to be used, method of accounting for usable parts, disposition of... pilot(s) and where the vessel will be docked. If a vessel is requested for permanent docking on water or...

41 CFR 102-37.230 - What must a letter of intent for obtaining surplus aircraft or vessels include?

Code of Federal Regulations, 2013 CFR

2013-07-01

..., name, class, size, displacement, length, beam, draft, lift capacity, and the hull or registry number... cannibalization process, how recovered parts are to be used, method of accounting for usable parts, disposition of... pilot(s) and where the vessel will be docked. If a vessel is requested for permanent docking on water or...

41 CFR 102-37.230 - What must a letter of intent for obtaining surplus aircraft or vessels include?

Code of Federal Regulations, 2014 CFR

2014-01-01

..., name, class, size, displacement, length, beam, draft, lift capacity, and the hull or registry number... cannibalization process, how recovered parts are to be used, method of accounting for usable parts, disposition of... pilot(s) and where the vessel will be docked. If a vessel is requested for permanent docking on water or...

Draft Genome Sequence of Pseudomonas pachastrellae Strain CCUG 46540T, a Deep-Sea Bacterium.

PubMed

Gomila, Margarita; Mulet, Magdalena; Lalucat, Jorge; García-Valdés, Elena

2017-04-06

Pseudomonas pachastrellae strain CCUG 46540 T (KMM 330 T ) was isolated from a deep-sea sponge specimen collected in the Philippine Sea at a depth of 750 m. The draft genome has an estimated size of 4.0 Mb, exhibits a G+C content of 61.2 mol%, and is predicted to encode 3,592 proteins, including pathways for the degradation of aromatic compounds. Copyright © 2017 Gomila et al.

Draft Genome Sequence of Pseudomonas oceani DSM 100277T, a Deep-Sea Bacterium.

PubMed

García-Valdés, Elena; Gomila, Margarita; Mulet, Magdalena; Lalucat, Jorge

2018-04-12

Pseudomonas oceani DSM 100277 T was isolated from deep seawater in the Okinawa Trough at 1390 m. P. oceani belongs to the Pseudomonas pertucinogena group. Here, we report the draft genome sequence of P. oceani , which has an estimated size of 4.1 Mb and exhibits 3,790 coding sequences, with a G+C content of 59.94 mol%. Copyright © 2018 García-Valdés et al.

Draft Genome Sequence of Pseudomonas pachastrellae Strain CCUG 46540T, a Deep-Sea Bacterium

PubMed Central

2017-01-01

ABSTRACT Pseudomonas pachastrellae strain CCUG 46540T (KMM 330T) was isolated from a deep-sea sponge specimen collected in the Philippine Sea at a depth of 750 m. The draft genome has an estimated size of 4.0 Mb, exhibits a G+C content of 61.2 mol%, and is predicted to encode 3,592 proteins, including pathways for the degradation of aromatic compounds. PMID:28385850

Simply actuated closure for a pressure vessel - Design for use to trap deep-sea animals

NASA Technical Reports Server (NTRS)

Yayanos, A. A.

1977-01-01

A pressure vessel is described that can be closed by a single translational motion within 1 sec. The vessel is a key component of a trap for small marine animals and operates automatically on the sea floor. As the vessel descends to the sea floor, it is subjected both internally and externally to the high pressures of the deep sea. The mechanism for closing the pressure vessel on the sea floor is activated by the timed release of the ballast which was used to sink the trap. As it rises to the sea surface, the internal pressure of the vessel remains near the value present on the sea floor. The pressure vessel has been used in simulated ocean deployments and in the deep ocean (9500 m) with a 75%-85% retention of the deep-sea pressure. Nearly 100% retention of pressure can be achieved by using an accumulator filled with a gas.

33 CFR 157.09 - Segregated ballast.

Code of Federal Regulations, 2010 CFR

2010-07-01

...) POLLUTION RULES FOR THE PROTECTION OF THE MARINE ENVIRONMENT RELATING TO TANK VESSELS CARRYING OIL IN BULK... more must have segregated ballast tanks that have a total capacity to allow the vessel to meet the draft and trim requirements in paragraph (b) of this section without recourse to the use of oil tanks...

Passenger Vessel Damage Stability Study for 1990 SOLAS Amendments. Volume 2. Appendix B

DTIC Science & Technology

1994-09-01

0.1 Note: Drafts are measured at A.P. and F.P alang ship’s centertine GE SUMMARY (Bvaluated per IKO (SOLAB󈨞) Rules for Passenger Ships) Available...Drafts are measured at A.P. and F.P alang ship’s centertine 03 SUNMIRY (Nvaluated per liO (8OLA1󈨞) Rules for Passenger Ships) Available Required...156.0 ------------------------------------ i- ------------ Note: Drafts are mesured at A.P. and F.P alang ship’s center ,Irw GZ SUMMARY (2valuateG per

Robust hepatic vessel segmentation using multi deep convolution network

NASA Astrophysics Data System (ADS)

Kitrungrotsakul, Titinunt; Han, Xian-Hua; Iwamoto, Yutaro; Foruzan, Amir Hossein; Lin, Lanfen; Chen, Yen-Wei

2017-03-01

Extraction of blood vessels of the organ is a challenging task in the area of medical image processing. It is really difficult to get accurate vessel segmentation results even with manually labeling by human being. The difficulty of vessels segmentation is the complicated structure of blood vessels and its large variations that make them hard to recognize. In this paper, we present deep artificial neural network architecture to automatically segment the hepatic vessels from computed tomography (CT) image. We proposed novel deep neural network (DNN) architecture for vessel segmentation from a medical CT volume, which consists of three deep convolution neural networks to extract features from difference planes of CT data. The three networks have share features at the first convolution layer but will separately learn their own features in the second layer. All three networks will join again at the top layer. To validate effectiveness and efficiency of our proposed method, we conduct experiments on 12 CT volumes which training data are randomly generate from 5 CT volumes and 7 using for test. Our network can yield an average dice coefficient 0.830, while 3D deep convolution neural network can yield around 0.7 and multi-scale can yield only 0.6.

77 FR 2741 - Draft Guidance Regarding Inspection and Certification of Vessels Under the Maritime Security Program

Federal Register 2010, 2011, 2012, 2013, 2014

2012-01-19

... traditional inspection methods to newly reflagged vessels, while at the same time apply a less stringent level... any one of the following methods: (1) Federal eRulemaking Portal: http://www.regulations.gov . (2) Fax... methods. See the ``Public Participation and Request for Comments'' portion of the SUPPLEMENTARY...

46 CFR 173.020 - Intact stability standards: Counterballasted and non-counterballasted vessels.

Code of Federal Regulations, 2010 CFR

2010-10-01

... not heel beyond the limits specified in paragraph (d) of this section: (1) Beam to depth—3.40 to 4.75...) of this section, the following limits of heel apply with the vessel at its deepest operating draft: (1) Protected and partially protected waters and Great Lakes in summer—heel to main deck immersion or...

46 CFR 173.020 - Intact stability standards: Counterballasted and non-counterballasted vessels.

Code of Federal Regulations, 2011 CFR

2011-10-01

... not heel beyond the limits specified in paragraph (d) of this section: (1) Beam to depth—3.40 to 4.75...) of this section, the following limits of heel apply with the vessel at its deepest operating draft: (1) Protected and partially protected waters and Great Lakes in summer—heel to main deck immersion or...

Draft Genome Sequence of Aldehyde-Degrading Strain Halomonas axialensis ACH-L-8

PubMed Central

Ye, Jun; Ren, Chong; Shan, Xiexie

2016-01-01

Halomonas axialensis ACH-L-8, a deep-sea strain isolated from the South China Sea, has the ability to degrade aldehydes. Here, we present an annotated draft genome sequence of this species, which could provide fundamental molecular information on the aldehydes-degrading mechanism. PMID:27081145

76 FR 9594 - Notice of Availability of the Draft Northern Arizona Proposed Withdrawal Environmental Impact...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-18

... availability of uranium resources; Dewatering of perched aquifers and changes in water availability in deep... 241A; AZA 035138] Notice of Availability of the Draft Northern Arizona Proposed Withdrawal... Management, Interior. ACTION: Notice of availability. SUMMARY: In accordance with the National Environmental...

33 CFR 157.10c - Segregated ballast tanks, crude oil washing systems, and dedicated clean ballast tanks for...

Code of Federal Regulations, 2011 CFR

2011-07-01

... to meet the draft and trim requirements in § 157.09(b); or (2) A crude oil washing system that meets... trim requirements in § 157.09(b); or (2) Dedicated clean ballast tanks that meet the design and... meet the draft and trim requirements in § 157.09(b). (d) If the arrangement of tanks on a vessel under...

33 CFR 157.10c - Segregated ballast tanks, crude oil washing systems, and dedicated clean ballast tanks for...

Code of Federal Regulations, 2010 CFR

2010-07-01

... to meet the draft and trim requirements in § 157.09(b); or (2) A crude oil washing system that meets... trim requirements in § 157.09(b); or (2) Dedicated clean ballast tanks that meet the design and... meet the draft and trim requirements in § 157.09(b). (d) If the arrangement of tanks on a vessel under...

Fine-grained visual marine vessel classification for coastal surveillance and defense applications

NASA Astrophysics Data System (ADS)

Solmaz, Berkan; Gundogdu, Erhan; Karaman, Kaan; Yücesoy, Veysel; Koç, Aykut

2017-10-01

The need for capabilities of automated visual content analysis has substantially increased due to presence of large number of images captured by surveillance cameras. With a focus on development of practical methods for extracting effective visual data representations, deep neural network based representations have received great attention due to their success in visual categorization of generic images. For fine-grained image categorization, a closely related yet a more challenging research problem compared to generic image categorization due to high visual similarities within subgroups, diverse applications were developed such as classifying images of vehicles, birds, food and plants. Here, we propose the use of deep neural network based representations for categorizing and identifying marine vessels for defense and security applications. First, we gather a large number of marine vessel images via online sources grouping them into four coarse categories; naval, civil, commercial and service vessels. Next, we subgroup naval vessels into fine categories such as corvettes, frigates and submarines. For distinguishing images, we extract state-of-the-art deep visual representations and train support-vector-machines. Furthermore, we fine tune deep representations for marine vessel images. Experiments address two scenarios, classification and verification of naval marine vessels. Classification experiment aims coarse categorization, as well as learning models of fine categories. Verification experiment embroils identification of specific naval vessels by revealing if a pair of images belongs to identical marine vessels by the help of learnt deep representations. Obtaining promising performance, we believe these presented capabilities would be essential components of future coastal and on-board surveillance systems.

26 CFR 48.4042-3 - Certain types of commercial waterway transportation excluded.

Code of Federal Regulations, 2010 CFR

2010-04-01

... Inland Waterways § 48.4042-3 Certain types of commercial waterway transportation excluded. (a) Deep draft... waters other than the territorial waters of the United States or any other country. Thus, the high seas... measured from the deepest appendage. A separage determination of draft must be made for each voyage when...

Contrasting hydraulic architecture and function in deep and shallow roots of tree species from a semi-arid habitat

PubMed Central

Johnson, Daniel M.; Brodersen, Craig R.; Reed, Mary; Domec, Jean-Christophe; Jackson, Robert B.

2014-01-01

Background and Aims Despite the importance of vessels in angiosperm roots for plant water transport, there is little research on the microanatomy of woody plant roots. Vessels in roots can be interconnected networks or nearly solitary, with few vessel–vessel connections. Species with few connections are common in arid habitats, presumably to isolate embolisms. In this study, measurements were made of root vessel pit sizes, vessel air-seeding pressures, pit membrane thicknesses and the degree of vessel interconnectedness in deep (approx. 20 m) and shallow (<10 cm) roots of two co-occurring species, Sideroxylon lanuginosum and Quercus fusiformis. Methods Scanning electron microscopy was used to image pit dimensions and to measure the distance between connected vessels. The number of connected vessels in larger samples was determined by using high-resolution computed tomography and three-dimensional (3-D) image analysis. Individual vessel air-seeding pressures were measured using a microcapillary method. The thickness of pit membranes was measured using transmission electron microscopy. Key Results Vessel pit size varied across both species and rooting depths. Deep Q. fusiformis roots had the largest pits overall (>500 µm) and more large pits than either shallow Q. fusiformis roots or S. lanuginosum roots. Vessel air-seeding pressures were approximately four times greater in Q. fusiformis than in S. lanuginosum and 1·3–1·9 times greater in shallow roots than in deep roots. Sideroxylon lanuginosum had 34–44 % of its vessels interconnected, whereas Q. fusiformis only had 1–6 % of its vessels connected. Vessel air-seeding pressures were unrelated to pit membrane thickness but showed a positive relationship with vessel interconnectedness. Conclusions These data support the hypothesis that species with more vessel–vessel integration are often less resistant to embolism than species with isolated vessels. This study also highlights the usefulness of tomography for vessel network analysis and the important role of 3-D xylem organization in plant hydraulic function. PMID:24363350

29 CFR 1918.2 - Definitions.

Code of Federal Regulations, 2012 CFR

2012-07-01

... adjacent surface; or (2) Whenever weather conditions may impair the vision or sound footing of employees.... River towboat means a shallow draft, low freeboard, self-propelled vessel designed to tow river barges...

76 FR 36511 - Fisheries of the Northeastern United States; Atlantic Deep-Sea Red Crab; Amendment 3

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-22

...-BA22 Fisheries of the Northeastern United States; Atlantic Deep-Sea Red Crab; Amendment 3 AGENCY... the Atlantic Deep-Sea Red Crab Fishery Management Plan (FMP) (Amendment 3), incorporating a draft... current trap limit regulations state that red crab may not be harvested from gear other than a marked red...

Multi-level deep supervised networks for retinal vessel segmentation.

PubMed

Mo, Juan; Zhang, Lei

2017-12-01

Changes in the appearance of retinal blood vessels are an important indicator for various ophthalmologic and cardiovascular diseases, including diabetes, hypertension, arteriosclerosis, and choroidal neovascularization. Vessel segmentation from retinal images is very challenging because of low blood vessel contrast, intricate vessel topology, and the presence of pathologies such as microaneurysms and hemorrhages. To overcome these challenges, we propose a neural network-based method for vessel segmentation. A deep supervised fully convolutional network is developed by leveraging multi-level hierarchical features of the deep networks. To improve the discriminative capability of features in lower layers of the deep network and guide the gradient back propagation to overcome gradient vanishing, deep supervision with auxiliary classifiers is incorporated in some intermediate layers of the network. Moreover, the transferred knowledge learned from other domains is used to alleviate the issue of insufficient medical training data. The proposed approach does not rely on hand-crafted features and needs no problem-specific preprocessing or postprocessing, which reduces the impact of subjective factors. We evaluate the proposed method on three publicly available databases, the DRIVE, STARE, and CHASE_DB1 databases. Extensive experiments demonstrate that our approach achieves better or comparable performance to state-of-the-art methods with a much faster processing speed, making it suitable for real-world clinical applications. The results of cross-training experiments demonstrate its robustness with respect to the training set. The proposed approach segments retinal vessels accurately with a much faster processing speed and can be easily applied to other biomedical segmentation tasks.

76 FR 10572 - Notice of Availability of a Draft Supplemental Environmental Impact Statement/Subsequent...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-25

... DEPARTMENT OF DEFENSE Department of the Army; Corps of Engineers Notice of Availability of a Draft... Deep Water Ship Channel AGENCY: Department of the Army, U.S. Army Corps of Engineers, DoD. ACTION... to reinitiate the previously authorized deepening from -30 feet mean lower low water (MLLW) to -35...

Draft Genome Sequence of the Spore-Forming Probiotic Strain Bacillus coagulans Unique IS-2

PubMed Central

Upadrasta, Aditya; Pitta, Swetha

2016-01-01

Bacillus coagulans Unique IS-2 is a potential spore-forming probiotic that is commercially available on the market. The draft genome sequence presented here provides deep insight into the beneficial features of this strain for its safe use as a probiotic for various human and animal health applications. PMID:27103709

76 FR 13396 - Notice of Availability of the Draft Environmental Impact Statement for the Mountaineer Commercial...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-11

... deep saline geologic formations for permanent geologic storage. DATES: DOE invites the public to...; or by fax (304) 285-4403. The Draft EIS is available on DOE's NEPA Web page at: http://nepa.energy.gov/DOE_NEPA_documents.htm ; and on the National Energy Technology Laboratory's Web page at: http...

46 CFR 131.513 - Verification of compliance with applicable stability requirements.

Code of Federal Regulations, 2011 CFR

2011-10-01

... its trim-and-stability book, stability letter, Certificate of Inspection, and Loadline Certificate... stability requirements, the master shall ascertain the vessel's draft, trim, and stability as necessary; and...

46 CFR 131.513 - Verification of compliance with applicable stability requirements.

Code of Federal Regulations, 2010 CFR

2010-10-01

... its trim-and-stability book, stability letter, Certificate of Inspection, and Loadline Certificate... stability requirements, the master shall ascertain the vessel's draft, trim, and stability as necessary; and...

[Applied anatomy of small saphenous vein and its distally-based sural nerve nutrient].

PubMed

Zhang, Fahui; Lin, Songqing; Zheng, Heping

2005-07-01

To investigate the origin of small saphenous vein of distally-based of sural nerve nutrient vessels flap and its clinical application. The origins of nutrient vessels of small saphenous vein and communicating branches of superficial-deep vein were observed on specimens of 30 adult cadaveric low limbs by perfusing red gelatin to dissect the artery. The nutrient vessels of small saphenous vein originated from the heel lateral artery, the terminal perforator branches of peroneal artery and intermuscular septum perforating branches of peroneal artery. There were 2 to 5 branches of such distally-based perforating branches whose diameters ranged from 0.6 to 1.0 mm. Those perforating branches included fascia branches, cutaneous branches nerve and vein nutrient branches. Those nutrient vessels formed a longitudinal vessel chain of clinical nerve shaft, vessel chain of vein side and vessel network of deep superficial fascia. The small saphenous vein had 1 to 2 communicating branches of superficial-deep vein whose diameter was 1.7+/-0.5 mm, 3.4+/-0.9 cm to the level of cusp of lateral malleolus, and converged into the fibular vein. Distally-based sural nerve, small saphenous vein, and nutrient vessels of fascia skin have the same region. The communicating branches of superficial-deep vein is 3 to 4 cm to the level of cusp lateral malleolus. These communicating branches could improve the venous drainage of the flap.

Bathymetric and oceanic controls on Abbot Ice Shelf thickness and stability

NASA Astrophysics Data System (ADS)

Cochran, J. R.; Jacobs, S. S.; Tinto, K. J.; Bell, R. E.

2014-05-01

Ice shelves play key roles in stabilizing Antarctica's ice sheets, maintaining its high albedo and returning freshwater to the Southern Ocean. Improved data sets of ice shelf draft and underlying bathymetry are important for assessing ocean-ice interactions and modeling ice response to climate change. The long, narrow Abbot Ice Shelf south of Thurston Island produces a large volume of meltwater, but is close to being in overall mass balance. Here we invert NASA Operation IceBridge (OIB) airborne gravity data over the Abbot region to obtain sub-ice bathymetry, and combine OIB elevation and ice thickness measurements to estimate ice draft. A series of asymmetric fault-bounded basins formed during rifting of Zealandia from Antarctica underlie the Abbot Ice Shelf west of 94° W and the Cosgrove Ice Shelf to the south. Sub-ice water column depths along OIB flight lines are sufficiently deep to allow warm deep and thermocline waters observed near the western Abbot ice front to circulate through much of the ice shelf cavity. An average ice shelf draft of ~200 m, 15% less than the Bedmap2 compilation, coincides with the summer transition between the ocean surface mixed layer and upper thermocline. Thick ice streams feeding the Abbot cross relatively stable grounding lines and are rapidly thinned by the warmest inflow. While the ice shelf is presently in equilibrium, the overall correspondence between draft distribution and thermocline depth indicates sensitivity to changes in characteristics of the ocean surface and deep waters.

Deep Lysimeter

DOEpatents

Hubbell, Joel M.; Sisson, James B.

2004-06-01

A deep lysimeter including a hollow vessel having a chamber, a fill conduit extending into the chamber through apertures, a semi-permeable member mounted on the vessel and in fluid communication with the fill conduit, and a line connection for retrieving the lysimeter.

76 FR 79620 - Fisheries of the Exclusive Economic Zone Off Alaska; Gulf of Alaska; Proposed 2012 and 2013...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-22

.... Apportionment of trawl PSC limits between the deep-water and shallow-water fisheries, limits for non-exempt... limit from the third season deep-water species fishery allowance for the GOA trawl fisheries to Rockfish... specifications. The draft 2011 SAFE reports indicate that the biomass trend for shallow-water flatfish, deep...

The Use of Simulators in Rules of the Road Training

DTIC Science & Technology

2013-12-01

ships and total losses (collision, contact, fire/explosion, foundering, wrecked /stranded, hull/machinery, missing and other) (from Sampson et al...number of ships and total losses (collision, contact, fire/explosion, foundering, wrecked /stranded, hull/machinery, missing and other) (from Sampson...another vessel at night, it would be a vessel ___ _ o (a) aground (b) constrained by her draft o (c) dredging o (d) moored over a wreck Post

Water-quality, bed-sediment, and discharge data for the Mississippi River-Gulf Outlet and adjacent waterways, southeastern Louisiana, August 2008 through December 2009

USGS Publications Warehouse

Swarzenski, Christopher M.; Mize, Scott V.; Lovelace, John K.

2012-01-01

The Mississippi River-Gulf Outlet navigation channel (MRGO) was constructed in the early 1960s to provide a safer and shorter route between the Gulf of Mexico and the Port of New Orleans for deep-draft, ocean-going vessels and to promote the economic development of the Port of New Orleans. In 2006, the U.S. Army Corps of Engineers developed a plan to de-authorize the MRGO. The plan called for a rock barrier to be constructed across the MRGO near Bayou La Loutre. In 2008, the U.S. Geological Survey, in cooperation with the Louisiana Coastal Area Science and Technology Program began a study to document the impacts of the rock barrier on water-quality and flow before, during, and after its construction. Water-quality, bed-sediment, and discharge data were collected in the MRGO and adjacent water bodies from August 2008 through December 2009.

78 FR 36496 - International Fisheries; Western and Central Pacific Fisheries for Highly Migratory Species...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-18

... number of vessels that engaged in both deep-setting and shallow-setting ranged from 17 to 35. The number... shallow-set and deep-set longlining. Based on an average of 127 active vessels during that period, the... analyses prepared for the 2009 rule are: (3) Shallow-set longline fishing for swordfish (for deep-setting...

33 CFR 117.585 - Acushnet River.

Code of Federal Regulations, 2011 CFR

2011-07-01

... Massachusetts, or by local authorities. (c) Each opening of the draw, from the time vehicular traffic flow is stopped until the flow resumes, shall not exceed 15 minutes except for vessels whose draft exceeds 15 feet...

33 CFR 117.585 - Acushnet River.

Code of Federal Regulations, 2012 CFR

2012-07-01

... Massachusetts, or by local authorities. (c) Each opening of the draw, from the time vehicular traffic flow is stopped until the flow resumes, shall not exceed 15 minutes except for vessels whose draft exceeds 15 feet...

33 CFR 148.215 - What if a port has plans for a deep draft channel and harbor?

Code of Federal Regulations, 2014 CFR

2014-07-01

...) Certification that the port has an active study by the Secretary of the Army for the construction of a deep... employment; and (D) Increases in tax revenues; (vii) Environmental and social impacts of the project on the...

Use of kurtosis for locating deep blood vessels in raw speckle imaging using a homogeneity representation.

PubMed

Peregrina-Barreto, Hayde; Perez-Corona, Elizabeth; Rangel-Magdaleno, Jose; Ramos-Garcia, Ruben; Chiu, Roger; Ramirez-San-Juan, Julio C

2017-06-01

Visualization of deep blood vessels in speckle images is an important task as it is used to analyze the dynamics of the blood flow and the health status of biological tissue. Laser speckle imaging is a wide-field optical technique to measure relative blood flow speed based on the local speckle contrast analysis. However, it has been reported that this technique is limited to certain deep blood vessels (about ? = 300 ?? ? m ) because of the high scattering of the sample; beyond this depth, the quality of the vessel’s image decreases. The use of a representation based on homogeneity values, computed from the co-occurrence matrix, is proposed as it provides an improved vessel definition and its corresponding diameter. Moreover, a methodology is proposed for automatic blood vessel location based on the kurtosis analysis. Results were obtained from the different skin phantoms, showing that it is possible to identify the vessel region for different morphologies, even up to 900 ?? ? m in depth.

Draft genome sequence of the novel strain Pseudomonas sp. 10B238 with potential ability to produce antibiotics from deep-sea sediment.

PubMed

Pan, Hua-Qi; Hu, Jiang-Chun

2015-10-01

Pseudomonas sp. 10B238 was a putatively novel species of Pseudomonas, isolated from a deep-sea sediment of the South China Sea, which had the genetic potential to produce secondary metabolites related to nonribosomal peptides (NRPs), as well as showed moderate antimicrobial activities. Here we report a high quality draft genome of Pseudomonas sp. 10B238, which comprises 4,933,052bp with the G+C content of 60.23%. A total of 11 potential secondary metabolite biosynthetic gene clusters were predicted, including a NRP for new peptide siderophore. And many anaerobic respiratory terminal enzymes were found for life in deep-sea environments. Our results may provide insights into biosynthetic pathway for antimicrobial bioactive compounds and be helpful to understand the physiological characteristic of this species. Copyright © 2015 Elsevier B.V. All rights reserved.

Draft Genome Sequence of Thermus scotoductus Strain K1, Isolated from a Geothermal Spring in Karvachar, Nagorno Karabakh

PubMed Central

Saghatelyan, Ani; Poghosyan, Lianna

2015-01-01

The 2,379,636-bp draft genome sequence of Thermus scotoductus strain K1, isolated from geothermal spring outlet located in the Karvachar region in Nagorno Karabakh is presented. Strain K1 shares about 80% genome sequence similarity with T. scotoductus strain SA-01, recovered from a deep gold mine in South Africa. PMID:26564055

Draft Genome Sequence of Bacillus stratosphericus LAMA 585, Isolated from the Atlantic Deep Sea

PubMed Central

Cabral, Alencar; Andreote, Fernando Dini; Cavalett, Angélica; Pessatti, Marcos Luiz; Dini-Andreote, Francisco; da Silva, Marcus Adonai Castro

2013-01-01

Bacillus stratosphericus LAMA 585 was isolated from the Mid-Atlantic-Ridge seafloor (5,500-m depth). This bacterium presents the capacity for cellulase, xylanase, and lipase production when growing aerobically in marine-broth media. Genes involved in the tolerance of oligotrophic and extreme conditions and prospection of biotechnological products were annotated in the draft genome (3.7 Mb). PMID:23640380

78 FR 48696 - Draft Revisions to the Marine Safety Manual, Volume III, Chapters 20-26

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-09

...) Updated provisions for vessel manning, including guidance for the issuing of safe manning documents; (2... Distress and Safety System (GMDSS), and the Principles of Minimum Safe Manning (IMO Resolution A.1047(27...

Increasing the Kill Effectiveness of High Energy Laser (HEL) Combat System

DTIC Science & Technology

2015-03-01

mm Machine Gun These versatile craft are Chinese imports. Some vessels have been configured without missiles in order to carry the larger MLRS...Displacement: 28.16 tons Armament: (2) 533 mm Torpedo Tubes Length: 21.12 m (1) 12.7 machine gun Beam: 5.77 m Draft: 0.87 m Speed: 20.6 m/s...m (2) Nasr ASM Draft: 0.67 m (2) 12.7 mm machine gun Speed: 26.7 m/s The original, low-observable torpedo boat, IPS-16 was imported from

Feasibility of potable water generators to meet vessel numeric ballast water discharge limits.

PubMed

Albert, Ryan J; Viveiros, Edward; Falatko, Debra S; Tamburri, Mario N

2017-07-15

Ballast water is taken on-board vessels into ballast water tanks to maintain vessel draft, buoyancy, and stability. Unmanaged ballast water contains aquatic organisms that, when transported and discharged to non-native waters, may establish as invasive species. Technologies capable of achieving regulatory limits designed to decrease the likelihood of invasion include onboard ballast water management systems. However, to date, the treatment development and manufacturing marketplace is limited to large vessels with substantial ballast requirements. For smaller vessels or vessels with reduced ballast requirements, we evaluated the feasibility of meeting the discharge limits by generating ballast water using onboard potable water generators. Case studies and parametric analyses demonstrated the architectural feasibility of installing potable water generators onboard actual vessels with minimal impacts for most vessel types evaluated. Furthermore, land-based testing of a potable water generator demonstrated capability to meet current numeric discharge limits for living organisms in all size classes. Published by Elsevier Ltd.

Draft Genome Sequence of Thalassospira xiamenensis Strain MCCC 1A03042T

PubMed Central

Li, Meiqing; Yang, Shuo; Lai, Qiliang

2017-01-01

ABSTRACT Thalassospira xiamenensis strain MCCC 1A03042T was isolated from deep-sea sediment of the Indian Ocean, and it was characterized with heavy-metal arsenic tolerance. Here, we present the draft genome of strain MCCC 1A03042T, which contains 4,786,207 bp with a G+C content of 52.6% and 4,359 protein-coding genes. PMID:28254975

Draft Genome Sequence of Thalassospira xiamenensis Strain MCCC 1A03042T.

PubMed

Li, Meiqing; Yang, Shuo; Lai, Qiliang; Shao, Zongze

2017-03-02

Thalassospira xiamenensis strain MCCC 1A03042 T was isolated from deep-sea sediment of the Indian Ocean, and it was characterized with heavy-metal arsenic tolerance. Here, we present the draft genome of strain MCCC 1A03042 T , which contains 4,786,207 bp with a G+C content of 52.6% and 4,359 protein-coding genes. Copyright © 2017 Li et al.

Draft Genome Sequence of Thermus scotoductus Strain K1, Isolated from a Geothermal Spring in Karvachar, Nagorno Karabakh.

PubMed

Saghatelyan, Ani; Poghosyan, Lianna; Panosyan, Hovik; Birkeland, Nils-Kåre

2015-11-12

The 2,379,636-bp draft genome sequence of Thermus scotoductus strain K1, isolated from geothermal spring outlet located in the Karvachar region in Nagorno Karabakh is presented. Strain K1 shares about 80% genome sequence similarity with T. scotoductus strain SA-01, recovered from a deep gold mine in South Africa. Copyright © 2015 Saghatelyan et al.

33 CFR 110.250 - St. Thomas Harbor, Charlotte Amalie, V.I.

Code of Federal Regulations, 2012 CFR

2012-07-01

..., V.I. (a) The anchorage grounds—(1) Inner harbor anchorage. Beginning at a point bearing 85°, 525... shall also be used by vessels having drafts too great to permit them to use the inner harbor anchorage...

33 CFR 110.250 - St. Thomas Harbor, Charlotte Amalie, V.I.

Code of Federal Regulations, 2014 CFR

2014-07-01

..., V.I. (a) The anchorage grounds—(1) Inner harbor anchorage. Beginning at a point bearing 85°, 525... shall also be used by vessels having drafts too great to permit them to use the inner harbor anchorage...

33 CFR 110.250 - St. Thomas Harbor, Charlotte Amalie, V.I.

Code of Federal Regulations, 2011 CFR

2011-07-01

..., V.I. (a) The anchorage grounds—(1) Inner harbor anchorage. Beginning at a point bearing 85°, 525... shall also be used by vessels having drafts too great to permit them to use the inner harbor anchorage...

33 CFR 110.250 - St. Thomas Harbor, Charlotte Amalie, V.I.

Code of Federal Regulations, 2013 CFR

2013-07-01

..., V.I. (a) The anchorage grounds—(1) Inner harbor anchorage. Beginning at a point bearing 85°, 525... shall also be used by vessels having drafts too great to permit them to use the inner harbor anchorage...

Radiated noise from commercial ships in the Gulf of Maine: implications for whale/vessel collisions.

PubMed

Allen, J Kaitlyn; Peterson, Michael L; Sharrard, George V; Wright, Dana L; Todd, Sean K

2012-09-01

To understand mysticete acoustic-based detection of ships, radiated noise from high-speed craft, cruise ships, catamarans and fishing vessels was recorded June-September 2009. Calibrated acoustic data (<2500 Hz) from a vertical hydrophone array was combined with ship passage information. A cruise ship had the highest broadband source level, while a fishing vessel had the lowest. Ship noise radiated asymmetrically and varied with depth. Bow null-effect acoustic shadow zones were observed for all ship classes and were correlated with ship-length-to-draft-ratios. These shadow zones may reduce ship detection by near-surface mysticetes.

Evaluation of Agency Non-Code Layered Pressure Vessels (LPVs) . Volume 2; Appendices

NASA Technical Reports Server (NTRS)

Prosser, William H.

2014-01-01

In coordination with the Office of Safety and Mission Assurance and the respective Center Pressure System Managers (PSMs), the NASA Engineering and Safety Center (NESC) was requested to formulate a consensus draft proposal for the development of additional testing and analysis methods to establish the technical validity, and any limitation thereof, for the continued safe operation of facility non-code layered pressure vessels. The PSMs from each NASA Center were asked to participate as part of the assessment team by providing, collecting, and reviewing data regarding current operations of these vessels. This document contains the appendices to the main report.

76 FR 35941 - Offer for Public Sale of Two High Speed Vessels

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-20

.... ALAKAI Hull: Length 321.2'. Beam 78.1'. Height to Upper Deck..... 30.8'. Design Draft at Transit.. 11.67... Kamewa 125 S11. Performance: Speed 35 knots 90% MCR 400 tons. HUAKAI Hull: Length 338.3'. Beam 78.1...

76 FR 76716 - Draft National Pollutant Discharge Elimination System (NPDES) General Permits for Discharges...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-08

...) the vessel has taken on ballast water that has a salinity of less than 18 ppt from a coastal... has not taken on ballast water with a salinity of less than 18 ppt in the previous month, the master...

15 CFR 762.3 - Records exempt from recordkeeping requirements.

Code of Federal Regulations, 2010 CFR

2010-01-01

...; (2) Special export file list; (3) Vessel log from freight forwarder; (4) Inspection certificate; (5... form; (12) Financial hold form; (13) Export parts shipping problem form; (14) Draft number log; (15) Expense invoice mailing log; (16) Financial status report; (17) Bank release of guarantees; (18) Cash...

15 CFR 762.3 - Records exempt from recordkeeping requirements.

Code of Federal Regulations, 2011 CFR

2011-01-01

...; (2) Special export file list; (3) Vessel log from freight forwarder; (4) Inspection certificate; (5... form; (12) Financial hold form; (13) Export parts shipping problem form; (14) Draft number log; (15) Expense invoice mailing log; (16) Financial status report; (17) Bank release of guarantees; (18) Cash...

Sea-Based X-Band (SBX) Radar Vessel Maintenance and Repair. Draft Environmental Assessment

DTIC Science & Technology

2011-02-14

crabs, lobsters, and shrimp), amphipods (small shrimp-like creatures), bivalves, barnacles, and gastropods (snails and slugs). Less common groups...A second phase will cover implementation of 10 years of post construction monitoring and adaptive management. Future 1 4.0 Cumulative Impacts

Evaluation of Agency Non-Code Layered Pressure Vessels (LPVs)

NASA Technical Reports Server (NTRS)

Prosser, William H.

2014-01-01

In coordination with the Office of Safety and Mission Assurance and the respective Center Pressure System Managers (PSMs), the NASA Engineering and Safety Center (NESC) was requested to formulate a consensus draft proposal for the development of additional testing and analysis methods to establish the technical validity, and any limitation thereof, for the continued safe operation of facility non-code layered pressure vessels. The PSMs from each NASA Center were asked to participate as part of the assessment team by providing, collecting, and reviewing data regarding current operations of these vessels. This report contains the outcome of the assessment and the findings, observations, and NESC recommendations to the Agency and individual NASA Centers.

Evaluation of Agency Non-Code Layered Pressure Vessels (LPVs). Corrected Copy, Aug. 25, 2014

NASA Technical Reports Server (NTRS)

Prosser, William H.

2014-01-01

In coordination with the Office of Safety and Mission Assurance and the respective Center Pressure System Managers (PSMs), the NASA Engineering and Safety Center (NESC) was requested to formulate a consensus draft proposal for the development of additional testing and analysis methods to establish the technical validity, and any limitation thereof, for the continued safe operation of facility non-code layered pressure vessels. The PSMs from each NASA Center were asked to participate as part of the assessment team by providing, collecting, and reviewing data regarding current operations of these vessels. This report contains the outcome of the assessment and the findings, observations, and NESC recommendations to the Agency and individual NASA Centers.

Linking Retinal Microvasculature Features With Severity of Diabetic Retinopathy Using Optical Coherence Tomography Angiography.

PubMed

Bhanushali, Devanshi; Anegondi, Neha; Gadde, Santosh G K; Srinivasan, Priya; Chidambara, Lavanya; Yadav, Naresh Kumar; Sinha Roy, Abhijit

2016-07-01

To correlate retinal vascular features with severity and systemic indicators of diabetic retinopathy (DR) using optical coherence tomography angiography (OCTA). A total of 209 eyes of 122 type 2 diabetes mellitus patients with DR and 60 eyes of 31 normal Indian subjects underwent OCTA imaging. The diabetic retinopathy patients were graded as having either nonproliferative diabetic retinopathy (NPDR: mild, moderate, and severe NPDR using Early Treatment Diabetic Retinopathy Study classification) or proliferative diabetic retinopathy (PDR). Local fractal analysis was applied to the superficial and deep retinal OCTA images. Foveal avascular zone area (FAZ in mm2); vessel density (%); spacing between large vessels (%); and spacing between small vessels (%) were analyzed. Sensitivity and specificity of vascular parameters were assessed with receiver operating characteristics (ROC) curve. Normal eyes had a significantly lower FAZ area, higher vessel density, and lower spacing between large and small vessels compared with DR grades (P < 0.001). In the superficial layer, PDR and severe NPDR had higher spacing between large vessels than mild and moderate NPDR (P = 0.04). However, mild NPDR had higher spacing between the small vessels (P < 0.001). Spacing between the large vessels in the superficial retinal layer correlated positively with HbA1c (r = 0.25, P = 0.03); fasting (r = 0.23, P = 0.02); and postprandial (r = 0.26, P = 0.03) blood sugar. The same spacing in the deep retinal vascular plexus had the highest area under the ROC curve (0.99 ± 0.01) and was uniformly elevated in all diabetic eyes (P > 0.05). Spacing between the large vessels in the superficial and deep retinal layers had superior diagnostic performance than overall vessel density.

46 CFR 199.630 - Alternatives for passenger vessels in a specified service.

Code of Federal Regulations, 2010 CFR

2010-10-01

... applies if the vessel operates in shallow water not more than 3 miles from shore where the vessel cannot sink deep enough to submerge the topmost deck. 5 Alternative applies if the vessel operates on... requirements for survival craft in § 199.201(b) if the vessel operates— (1) On a route that is in shallow water...

Draft Genome Sequence of Pseudoalteromonas sp. Strain ND6B, an Oil-Degrading Isolate from Eastern Mediterranean Sea Water Collected at a Depth of 1,210 Meters

DOE PAGES

Harris, Austin P.; Techtmann, Stephen M.; Stelling, Savannah C.; ...

2014-11-26

We report the draft genome of Pseudoalteromonas sp. strain ND6B, which is able to grow with crude oil as a carbon source. Strain ND6B was isolated from eastern Mediterranean Sea deep water at a depth of 1,210 m. The genome of strain ND6B provides insight into the oil-degrading ability of the Pseudoalteromonas species.

Lummi Bay Marina, Whatcom County, Washington. Draft Detailed Project Report and Draft Environmental Impact Statement.

DTIC Science & Technology

1983-12-01

observations of qray whales from the waters inside of Wasbington including the eastern Strait of Juan de ruca, the San Juan Islands, Puget Sound , and Hood...waters in winter. in the North Pacific this E.ecies is presently estimated tc number about 17,000 animals. One fin whale was pursued in Puget Sound i...owns submerged lands from tideland elevation -4.5 feet MLLW to deep water in Puget Sound . The Lummi Tribe (local sponsor) owns Reservation lands above

46 CFR 171.010 - Definitions.

Code of Federal Regulations, 2013 CFR

2013-10-01

... weather deck extending no more than one-half of the vessel's length over deck (LOD) measured over the weather deck. (b) Deepest subdivision load line means the waterline that corresponds to the deepest draft... tangent to the waterline. (g) Flush deck means a continuous weather deck located at the uppermost sheer...

46 CFR 171.010 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-10-01

... weather deck extending no more than one-half of the vessel's length over deck (LOD) measured over the weather deck. (b) Deepest subdivision load line means the waterline that corresponds to the deepest draft... tangent to the waterline. (g) Flush deck means a continuous weather deck located at the uppermost sheer...

Supercharging the transverse rectus abdominis musculocutaneous flap: breast reconstruction for the overweight and obese population.

PubMed

Wu, Liza C; Iteld, Lawrence; Song, David H

2008-06-01

Autologous breast reconstruction with the transverse rectus abdominis musculocutaneous (TRAM) flap is traditionally based on either the superior epigastric vessels (pedicled) or the deep inferior system (free). In the overweight and obese population, both techniques have been shown to have increased complications of the reconstructed breast. Another alternative is supercharging the flap by anastamosing the deep inferior epigastric vessels to either the internal mammary or thoracodorsal systems. We present a single surgeon's experience with unilateral TRAM reconstructions supercharged to either the thoracodorsal vessels, the internal mammary system, or in one case, perforator vessels in overweight and obese patients. Nineteen consecutive overweight or obese patients underwent delayed or immediate, unilateral autologous breast reconstruction with supercharged TRAM flaps between November 2000 and November 2004. The patients ranged in age from 28 to 66 years (average 49) and had an average body mass index (BMI) of 29.5 (24.9-38.3). Twelve patients had a BMI between 25 and 29.9 kg/m2; 7 patients had BMI > or =30 kg/m2. Left-sided reconstructions were 13; right-sided reconstructions were 6. Supercharging was performed by anastamosing the deep inferior epigastric artery and vein to the thoracodorsal vessels, internal mammary vessels, or perforator vessels. Follow-up ranged from 6 to 54 months. There was a qualitative increase in blood flow measured by audible Doppler signals in all patients after the arterial and venous anastamoses. There were no cases of partial or complete flap loss. One patient had a hematoma and subsequently developed minor fat necrosis. One patient had an infection of the reconstructed breast. There were no donor site complications. Supercharging the TRAM flap by means of microvascular augmentation of the deep inferior epigastric vessels provides a safe and effective breast reconstruction in the overweight and obese population with no additional morbidity.

46 CFR 117.207 - Survival craft-vessels operating on lakes, bays, and sounds routes.

Code of Federal Regulations, 2010 CFR

2010-10-01

... survival craft. (e) For a vessel certificated to operate on a lakes, bays, and sounds route in shallow water where the vessel can not sink deep enough to submerge the topmost passenger deck or where...

Xylem development in prunus flower buds and the relationship to deep supercooling.

PubMed

Ashworth, E N

1984-04-01

Xylem development in eight Prunus species was examined and the relationship to deep supercooling assessed. Dormant buds of six species, P. armeniaca, P. avium, P. cerasus, P. persica, P. salicina, and P. sargentii deep supercooled. Xylem vessel elements were not observed within the dormant floral primordia of these species. Instead, discrete bundles containing procambial cells were observed. Vascular differentiation resumed and xylem continuity was established during the time that the capacity to deep supercool was lost. In P. serotina and P. virginiana, two species which do not supercool, xylem vessels ran the length of the inflorescence and presumably provided a conduit for the spread of ice into the bud. The results support the hypothesis that the lack of xylem continuity is an important feature of buds which deep supercool.

15 CFR 970.205 - Vessel safety.

Code of Federal Regulations, 2013 CFR

2013-01-01

... AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE GENERAL REGULATIONS OF THE ENVIRONMENTAL DATA SERVICE DEEP SEABED MINING REGULATIONS FOR EXPLORATION LICENSES Applications Contents § 970.205 Vessel...

15 CFR 970.205 - Vessel safety.

Code of Federal Regulations, 2012 CFR

2012-01-01

... AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE GENERAL REGULATIONS OF THE ENVIRONMENTAL DATA SERVICE DEEP SEABED MINING REGULATIONS FOR EXPLORATION LICENSES Applications Contents § 970.205 Vessel...

15 CFR 970.205 - Vessel safety.

Code of Federal Regulations, 2014 CFR

2014-01-01

... AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE GENERAL REGULATIONS OF THE ENVIRONMENTAL DATA SERVICE DEEP SEABED MINING REGULATIONS FOR EXPLORATION LICENSES Applications Contents § 970.205 Vessel...

15 CFR 970.205 - Vessel safety.

Code of Federal Regulations, 2010 CFR

2010-01-01

... AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE GENERAL REGULATIONS OF THE ENVIRONMENTAL DATA SERVICE DEEP SEABED MINING REGULATIONS FOR EXPLORATION LICENSES Applications Contents § 970.205 Vessel...

15 CFR 970.205 - Vessel safety.

Code of Federal Regulations, 2011 CFR

2011-01-01

... AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE GENERAL REGULATIONS OF THE ENVIRONMENTAL DATA SERVICE DEEP SEABED MINING REGULATIONS FOR EXPLORATION LICENSES Applications Contents § 970.205 Vessel...

Optical coherence tomography angiography indicates associations of the retinal vascular network and disease activity in multiple sclerosis.

PubMed

Feucht, Nikolaus; Maier, Mathias; Lepennetier, Gildas; Pettenkofer, Moritz; Wetzlmair, Carmen; Daltrozzo, Tanja; Scherm, Pauline; Zimmer, Claus; Hoshi, Muna-Miriam; Hemmer, Bernhard; Korn, Thomas; Knier, Benjamin

2018-01-01

Patients with multiple sclerosis (MS) and clinically isolated syndrome (CIS) may show alterations of retinal layer architecture as measured by optical coherence tomography. Little is known about changes in the retinal vascular network during MS. To characterize retinal vessel structures in patients with MS and CIS and to test for associations with MS disease activity. In all, 42 patients with MS or CIS and 50 healthy controls underwent retinal optical coherence tomography angiography (OCT-A) with analysis of the superficial and deep vascular plexuses and the choriocapillaries. We tested OCT-A parameters for associations with retinal layer volumes, history of optic neuritis (ON), and the retrospective disease activity. Inner retinal layer volumes correlated positively with the density of both the superficial and deep vascular plexuses. Eyes of MS/CIS patients with a history of ON revealed reduced vessel densities of the superficial and deep vascular plexuses as compared to healthy controls. Higher choriocapillary vessel densities were associated with ongoing inflammatory disease activity during 24 months prior to OCT-A examination in MS and CIS patients. Optic neuritis is associated with rarefaction of the superficial and deep retinal vessels. Alterations of the choriocapillaries might be linked to disease activity in MS.

31 CFR 515.571 - Certain transactions incident to travel to, from, and within the United States by Cuban nationals.

Code of Federal Regulations, 2010 CFR

2010-07-01

... maintenance within the United States, including the payment of living expenses and the acquisition of goods for personal consumption in the United States; (3) All transactions on behalf of aircraft or vessels... banking transactions involving foreign currency drafts, travelers' checks, or other instruments negotiated...

31 CFR 515.571 - Certain transactions incident to travel to, from, and within the United States by Cuban nationals.

Code of Federal Regulations, 2011 CFR

2011-07-01

... maintenance within the United States, including the payment of living expenses and the acquisition of goods for personal consumption in the United States; (3) All transactions on behalf of aircraft or vessels... banking transactions involving foreign currency drafts, travelers' checks, or other instruments negotiated...

31 CFR 515.571 - Certain transactions incident to travel to, from, and within the United States by Cuban nationals.

Code of Federal Regulations, 2014 CFR

2014-07-01

... maintenance within the United States, including the payment of living expenses and the acquisition of goods for personal consumption in the United States; (3) All transactions on behalf of aircraft or vessels... banking transactions involving foreign currency drafts, travelers' checks, or other instruments negotiated...

31 CFR 515.571 - Certain transactions incident to travel to, from, and within the United States by Cuban nationals.

Code of Federal Regulations, 2012 CFR

2012-07-01

... maintenance within the United States, including the payment of living expenses and the acquisition of goods for personal consumption in the United States; (3) All transactions on behalf of aircraft or vessels... banking transactions involving foreign currency drafts, travelers' checks, or other instruments negotiated...

31 CFR 515.571 - Certain transactions incident to travel to, from, and within the United States by Cuban nationals.

Code of Federal Regulations, 2013 CFR

2013-07-01

... maintenance within the United States, including the payment of living expenses and the acquisition of goods for personal consumption in the United States; (3) All transactions on behalf of aircraft or vessels... banking transactions involving foreign currency drafts, travelers' checks, or other instruments negotiated...

75 FR 52555 - Notice of Availability of a Draft Site-Specific Environmental Assessment and Notice of Public...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-26

... vessel cruises (expeditions) as the predominate means to make direct measurements of the ocean. Remote sensing (use of satellites) has greatly advanced abilities to measure ocean surface characteristics over... sensing in the Eastern Pacific and Atlantic oceans. The Regional-Scale Nodes (RSN) off the coast of...

15 CFR 971.701 - Criteria for safety of life and property at sea.

Code of Federal Regulations, 2010 CFR

2010-01-01

... REGULATIONS OF THE ENVIRONMENTAL DATA SERVICE DEEP SEABED MINING REGULATIONS FOR COMMERCIAL RECOVERY PERMITS... by present laws and regulations. The primary inspection statutes pertaining to United States flag... Motor Vessels, and Freight Vessels). United States flag vessels will be required to meet all applicable...

48 CFR 47.501 - Definitions.

Code of Federal Regulations, 2011 CFR

2011-10-01

... of bulk liquid cargoes such as liquid petroleum products, vegetable oils, and molasses. U.S.-flag... cargoes of dry bulk items or, when carried in deep tanks, bulk liquids such as petroleum and vegetable oils. Foreign-flag vessel means any vessel of foreign registry including vessels owned by U.S. citizens...

48 CFR 47.501 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-10-01

... of bulk liquid cargoes such as liquid petroleum products, vegetable oils, and molasses. U.S.-flag... cargoes of dry bulk items or, when carried in deep tanks, bulk liquids such as petroleum and vegetable oils. Foreign-flag vessel means any vessel of foreign registry including vessels owned by U.S. citizens...

Technology Assessment for External Implementation of Artificial Gravity Utilizing the Deep Space Gateway Platform

NASA Astrophysics Data System (ADS)

Raychev, R.; Griko, Y. V.

2018-02-01

Scenario drafting for early technology assessment of the external space centrifuge with little mass and variable radius of rotation is proposed to counteract micro gravity-associated physiological alterations in all physiological systems.

50 CFR 229.37 - False Killer Whale Take Reduction Plan.

Code of Federal Regulations, 2014 CFR

2014-10-01

... Hawaii Pelagic and Hawaii Insular stocks of false killer whales in the Hawaii-based deep-set and shallow... section have the following meanings: (1) Deep-set or Deep-setting has the same meaning as the definition... this title. (c) Gear requirements. (1) While deep-setting, the owner and operator of a vessel...

50 CFR 229.37 - False Killer Whale Take Reduction Plan.

Code of Federal Regulations, 2013 CFR

2013-10-01

... Hawaii Pelagic and Hawaii Insular stocks of false killer whales in the Hawaii-based deep-set and shallow... section have the following meanings: (1) Deep-set or Deep-setting has the same meaning as the definition... this title. (c) Gear requirements. (1) While deep-setting, the owner and operator of a vessel...

Factors affecting stranding of juvenile salmonids by wakes from ship passage in the Lower Columbia River

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pearson, Walter H.; Skalski, John R.

2011-09-01

The effects of deep-draft vessel traffic in confined riverine channels on shorelines and fish are of widespread concern. In the Pacific Northwest of the United States, wakes and subsequent beach run-up from ships transiting the Lower Columbia River have been observed to strand juvenile salmon and other fish. As part of a before-and-after study to assess stranding effects that may be associated with channel deepening, we measured 19 co-variables from observations of 126 vessel passages at three low-slope beaches and used multiple logistic regression to discern the significant factors influencing the frequency of stranding. Subyearling Chinook salmon were 82% ofmore » the fish stranded over all sites and seasons. Given a low-slope beach, stranding frequencies for juvenile salmon were significantly related to river location, salmon density in the shallows, a proxy for ship kinetic energy, tidal height, and two interactions. The beach types selected for our study do not include all the beach types along the Lower Columbia River so that the stranding probabilities described here cannot be extrapolated river-wide. A more sophisticated modeling effort, informed by additional field data, is needed to assess salmon losses by stranding for the entire lower river. Such modeling needs to include river-scale factors such as beach type, berms, proximity to navigation channel, and perhaps, proximity to tributaries that act as sources of out-migrating juvenile salmon. At both river and beach scales, no one factor produces stranding; rather interactions among several conditions produce a stranding event and give stranding its episodic nature.« less

Xylem Development in Prunus Flower Buds and the Relationship to Deep Supercooling

PubMed Central

Ashworth, Edward N.

1984-01-01

Xylem development in eight Prunus species was examined and the relationship to deep supercooling assessed. Dormant buds of six species, P. armeniaca, P. avium, P. cerasus, P. persica, P. salicina, and P. sargentii deep supercooled. Xylem vessel elements were not observed within the dormant floral primordia of these species. Instead, discrete bundles containing procambial cells were observed. Vascular differentiation resumed and xylem continuity was established during the time that the capacity to deep supercool was lost. In P. serotina and P. virginiana, two species which do not supercool, xylem vessels ran the length of the inflorescence and presumably provided a conduit for the spread of ice into the bud. The results support the hypothesis that the lack of xylem continuity is an important feature of buds which deep supercool. Images Fig. 1 Fig. 2 Fig. 3 Fig. 4 Fig. 5 Fig. 6 PMID:16663523

75 FR 2111 - New England Fishery Management Council; Public Hearings

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-14

... catch targets and associated days-at-sea (DAS) and trip limits for the directed fishery to supplant the... their allocated groundfish DAS, to require all limited access monkfish vessels to use a VMS when on a monkfish DAS, and to allow the landing of monkfish heads. The public hearing document, as well as the draft...

15 CFR 971.205 - Vessel safety and documentation.

Code of Federal Regulations, 2010 CFR

2010-01-01

... THE ENVIRONMENTAL DATA SERVICE DEEP SEABED MINING REGULATIONS FOR COMMERCIAL RECOVERY PERMITS... research: (a) U.S. flag vessel. All mining ships and at least one of the transport ships used by each...

Could Nano-Structured Materials Enable the Improved Pressure Vessels for Deep Atmospheric Probes?

NASA Technical Reports Server (NTRS)

Srivastava, D.; Fuentes, A.; Bienstock, B.; Arnold, J. O.

2005-01-01

A viewgraph presentation on the use of Nano-Structured Materials to enable pressure vessel structures for deep atmospheric probes is shown. The topics include: 1) High Temperature/Pressure in Key X-Environments; 2) The Case for Use of Nano-Structured Materials Pressure Vessel Design; 3) Carbon based Nanomaterials; 4) Nanotube production & purification; 5) Nanomechanics of Carbon Nanotubes; 6) CNT-composites: Example (Polymer); 7) Effect of Loading sequence on Composite with 8% by volume; 8) Models for Particulate Reinforced Composites; 9) Fullerene/Ti Composite for High Strength-Insulating Layer; 10) Fullerene/Epoxy Composite for High Strength-Insulating Layer; 11) Models for Continuous Fiber Reinforced Composites; 12) Tensile Strength for Discontinuous Fiber Composite; 13) Ti + SWNT Composites: Thermal/Mechanical; 14) Ti + SWNT Composites: Tensile Strength; and 15) Nano-structured Shell for Pressure Vessels.

LOOP marine and estuarine monitoring program, 1978-95 : volume 6 : sediment quality.

DOT National Transportation Integrated Search

1998-01-01

The Louisiana Offshore Oil Port (LOOP) facilities in coastal Louisiana provide the United States with the country's only Superport for off-loading deep draft tankers. Sediment samples were collected quarterly from 1970 through 1995 at designated stat...

LOOP marine and estuarine monitoring program, 1978-95 : volume 5 : demersal nekton.

DOT National Transportation Integrated Search

1998-01-01

The Louisiana Offshore Oil Port (LOOP) facilities in coastal Louisiana provide the United States with the country's only Superport for off-loading deep draft tankers. The facilities transport oil ashore through pipelines, and temporarily store oil be...

77 FR 35850 - Safety Zone; F/V Deep Sea, Penn Cove, WA

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-15

... 1625-AA00 Safety Zone; F/V Deep Sea, Penn Cove, WA AGENCY: Coast Guard, DHS. ACTION: Temporary final rule. SUMMARY: The Coast Guard is establishing a safety zone around the Fishing Vessel (F/V) Deep Sea... with the sunken F/V Deep Sea. B. Basis and Purpose On the evening of May 13, 2012, the F/V Deep Sea...

LOOP marine and estuarine monitoring program, 1978-95 : volume 4 : zooplankton and ichthyoplankton.

DOT National Transportation Integrated Search

1998-01-01

The Louisiana Offshore Oil Port (LOOP) facilities in coastal Louisiana provide the United States with the country's only Superport for off-loading deep draft tankers. The three single-point mooring (SPM) structures connected by pipelines to a platfor...

Finite Element Analysis of Deep Wide-Flanged Pre-stressed Girders : Draft Final Report

DOT National Transportation Integrated Search

2011-06-01

Hundreds of prestressed concrete girders are used each year for building bridges in Wisconsin. : The prestress transfer from the prestressing strands to concrete takes place at the girder ends. : Characteristic cracks form in this end region during o...

33 CFR 207.640 - Sacramento Deep Water Ship Channel Barge Lock and Approach Canals; use, administration, and...

Code of Federal Regulations, 2010 CFR

2010-07-01

... Engineer District, Sacramento, Federal and Courts Building, 650 Capitol Avenue, Sacramento, California. His... green light is flashing, lock is ready for entrance, the vessel may proceed with caution into the lock... or canal. Vessel may enter canal with caution. When the green light is on, vessel may enter canal and...

50 CFR 648.262 - Effort-control program for red crab limited access vessels.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 50 Wildlife and Fisheries 8 2010-10-01 2010-10-01 false Effort-control program for red crab... UNITED STATES Management Measures for the Atlantic Deep-Sea Red Crab Fishery § 648.262 Effort-control program for red crab limited access vessels. (a) General. A vessel issued a limited access red crab permit...

77 FR 46338 - Fisheries of the Economic Exclusive Zone Off Alaska; Deep-Water Species Fishery by Vessels Using...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-08-03

.... 111207737-2141-02] RIN 0648-XC142 Fisheries of the Economic Exclusive Zone Off Alaska; Deep-Water Species...: NMFS is prohibiting directed fishing for species that comprise the deep-water species fishery by... apportionment of the Pacific halibut bycatch allowance specified for the deep-water species fishery in the GOA...

78 FR 30242 - Fisheries of the Economic Exclusive Zone Off Alaska; Deep-Water Species Fishery by Vessels Using...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-22

.... 120918468-3111-02] RIN 0648-XC675 Fisheries of the Economic Exclusive Zone Off Alaska; Deep-Water Species...: NMFS is prohibiting directed fishing for species that comprise the deep-water species fishery by... apportionment of the Pacific halibut bycatch allowance specified for the deep-water species fishery in the GOA...

75 FR 23189 - Fisheries of the Economic Exclusive Zone Off Alaska; Deep-Water Species Fishery by Vessels Using...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-05-03

.... 0910131362-0087-02] RIN 0648-XW20 Fisheries of the Economic Exclusive Zone Off Alaska; Deep-Water Species...: NMFS is prohibiting directed fishing for species that comprise the deep-water species fishery by... apportionment of the Pacific halibut bycatch allowance specified for the deep-water species fishery in the GOA...

77 FR 24154 - Fisheries of the Economic Exclusive Zone Off Alaska; Deep-Water Species Fishery by Vessels Using...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-23

.... 111207737-2141-02] RIN 0648-XC001 Fisheries of the Economic Exclusive Zone Off Alaska; Deep-Water Species...: NMFS is prohibiting directed fishing for species that comprise the deep-water species fishery by... apportionment of the Pacific halibut bycatch allowance specified for the deep-water species fishery in the GOA...

76 FR 23511 - Fisheries of the Economic Exclusive Zone Off Alaska; Deep-Water Species Fishery by Vessels Using...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-27

.... 101126522-0640-02] RIN 0648-XA394 Fisheries of the Economic Exclusive Zone Off Alaska; Deep-Water Species...: NMFS is prohibiting directed fishing for species that comprise the deep-water species fishery by... apportionment of the Pacific halibut bycatch allowance specified for the deep-water species fishery in the GOA...

46 CFR 169.537 - Description of equipment for lifefloats.

Code of Federal Regulations, 2014 CFR

2014-10-01

... between the deck on which the life float(s) are stowed and the light draft of the vessel, (2) Have a... persons or more, the breaking strength must be at least 13.4 KN (3000 lbs.), (3) Be of a dark color, if synthetic, or of a type certified to be resistant to deterioration from ultraviolet light, and (4) Be stowed...

46 CFR 169.537 - Description of equipment for lifefloats.

Code of Federal Regulations, 2010 CFR

2010-10-01

... between the deck on which the life float(s) are stowed and the light draft of the vessel, (2) Have a... persons or more, the breaking strength must be at least 13.4 KN (3000 lbs.), (3) Be of a dark color, if synthetic, or of a type certified to be resistant to deterioration from ultraviolet light, and (4) Be stowed...

46 CFR 169.537 - Description of equipment for lifefloats.

Code of Federal Regulations, 2013 CFR

2013-10-01

... between the deck on which the life float(s) are stowed and the light draft of the vessel, (2) Have a... persons or more, the breaking strength must be at least 13.4 KN (3000 lbs.), (3) Be of a dark color, if synthetic, or of a type certified to be resistant to deterioration from ultraviolet light, and (4) Be stowed...

Case Analysis Of The Joint High Speed Vessel Program: Defense Acquisition

DTIC Science & Technology

2016-09-01

reviews resulted in a series of Advanced Concept Technology Demonstrations (ACTD) designed to explore the military utility of converted commercial...requirements into a final and unique materiel solution for a system capability that is fielded. 14. SUBJECT TERMS Advanced Concept and Technology ...Advanced Concept Technology Demonstrations (ACTD) designed to explore the military utility of converted commercial, high-speed, shallow-draft

15 CFR 971.1005 - Observers.

Code of Federal Regulations, 2012 CFR

2012-01-01

... AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE GENERAL REGULATIONS OF THE ENVIRONMENTAL DATA SERVICE DEEP SEABED MINING REGULATIONS FOR COMMERCIAL RECOVERY PERMITS Enforcement § 971.1005 Observers.... The Administrator shall require the placement of an observer on each permittee's mining vessel(s) at...

15 CFR 971.1005 - Observers.

Code of Federal Regulations, 2013 CFR

2013-01-01

... AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE GENERAL REGULATIONS OF THE ENVIRONMENTAL DATA SERVICE DEEP SEABED MINING REGULATIONS FOR COMMERCIAL RECOVERY PERMITS Enforcement § 971.1005 Observers.... The Administrator shall require the placement of an observer on each permittee's mining vessel(s) at...

15 CFR 971.1005 - Observers.

Code of Federal Regulations, 2014 CFR

2014-01-01

... AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE GENERAL REGULATIONS OF THE ENVIRONMENTAL DATA SERVICE DEEP SEABED MINING REGULATIONS FOR COMMERCIAL RECOVERY PERMITS Enforcement § 971.1005 Observers.... The Administrator shall require the placement of an observer on each permittee's mining vessel(s) at...

15 CFR 971.1005 - Observers.

Code of Federal Regulations, 2011 CFR

2011-01-01

... AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE GENERAL REGULATIONS OF THE ENVIRONMENTAL DATA SERVICE DEEP SEABED MINING REGULATIONS FOR COMMERCIAL RECOVERY PERMITS Enforcement § 971.1005 Observers.... The Administrator shall require the placement of an observer on each permittee's mining vessel(s) at...

15 CFR 971.1005 - Observers.

Code of Federal Regulations, 2010 CFR

2010-01-01

... AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE GENERAL REGULATIONS OF THE ENVIRONMENTAL DATA SERVICE DEEP SEABED MINING REGULATIONS FOR COMMERCIAL RECOVERY PERMITS Enforcement § 971.1005 Observers.... The Administrator shall require the placement of an observer on each permittee's mining vessel(s) at...

Yucca Mountain nuclear waste repository prompts heated congressional hearing

NASA Astrophysics Data System (ADS)

Showstack, Randy

2011-11-01

Although the final report of the Blue Ribbon Commission on America's Nuclear Future is not expected until January 2012, the tentative conclusions of the commission's draft report were dissected during a recent joint hearing by two subcommittees of the House of Representatives' Committee on Science, Space, and Technology. Among the more heated issues debated at the hearing was the fate of the stalled Yucca Mountain nuclear waste repository in Nevada. The Blue Ribbon Commission's (BRC) draft report includes recommendations for managing nuclear waste and for developing one or more permanent deep geological repositories and interim storage facilities, but the report does not address the future of Yucca Mountain. The BRC charter indicates that the commission is to "conduct a comprehensive review of policies for managing the back end of the nuclear fuel cycle." However, the draft report states that the commission was not asked to consider, and therefore did not address, several key issues. "We have not rendered an opinion on the suitability of the Yucca Mountain site or on the request to withdraw the license application for Yucca Mountain," the draft report states.

15 CFR 971.212 - Public notice, hearing and comment.

Code of Federal Regulations, 2014 CFR

2014-01-01

... THE ENVIRONMENTAL DATA SERVICE DEEP SEABED MINING REGULATIONS FOR COMMERCIAL RECOVERY PERMITS... commercial recovery permit, notice that the application has been received. Subject to § 971.802, interested... public hearing on the application and the draft EIS in an appropriate location and may employ additional...

15 CFR 971.212 - Public notice, hearing and comment.

Code of Federal Regulations, 2013 CFR

2013-01-01

... THE ENVIRONMENTAL DATA SERVICE DEEP SEABED MINING REGULATIONS FOR COMMERCIAL RECOVERY PERMITS... commercial recovery permit, notice that the application has been received. Subject to § 971.802, interested... public hearing on the application and the draft EIS in an appropriate location and may employ additional...

15 CFR 971.212 - Public notice, hearing and comment.

Code of Federal Regulations, 2011 CFR

2011-01-01

... THE ENVIRONMENTAL DATA SERVICE DEEP SEABED MINING REGULATIONS FOR COMMERCIAL RECOVERY PERMITS... commercial recovery permit, notice that the application has been received. Subject to § 971.802, interested... public hearing on the application and the draft EIS in an appropriate location and may employ additional...

15 CFR 971.212 - Public notice, hearing and comment.

Code of Federal Regulations, 2012 CFR

2012-01-01

... THE ENVIRONMENTAL DATA SERVICE DEEP SEABED MINING REGULATIONS FOR COMMERCIAL RECOVERY PERMITS... commercial recovery permit, notice that the application has been received. Subject to § 971.802, interested... public hearing on the application and the draft EIS in an appropriate location and may employ additional...

Deep Learning for Prediction of Obstructive Disease From Fast Myocardial Perfusion SPECT: A Multicenter Study.

PubMed

Betancur, Julian; Commandeur, Frederic; Motlagh, Mahsaw; Sharir, Tali; Einstein, Andrew J; Bokhari, Sabahat; Fish, Mathews B; Ruddy, Terrence D; Kaufmann, Philipp; Sinusas, Albert J; Miller, Edward J; Bateman, Timothy M; Dorbala, Sharmila; Di Carli, Marcelo; Germano, Guido; Otaki, Yuka; Tamarappoo, Balaji K; Dey, Damini; Berman, Daniel S; Slomka, Piotr J

2018-03-12

The study evaluated the automatic prediction of obstructive disease from myocardial perfusion imaging (MPI) by deep learning as compared with total perfusion deficit (TPD). Deep convolutional neural networks trained with a large multicenter population may provide improved prediction of per-patient and per-vessel coronary artery disease from single-photon emission computed tomography MPI. A total of 1,638 patients (67% men) without known coronary artery disease, undergoing stress 99m Tc-sestamibi or tetrofosmin MPI with new generation solid-state scanners in 9 different sites, with invasive coronary angiography performed within 6 months of MPI, were studied. Obstructive disease was defined as ≥70% narrowing of coronary arteries (≥50% for left main artery). Left ventricular myocardium was segmented using clinical nuclear cardiology software and verified by an expert reader. Stress TPD was computed using sex- and camera-specific normal limits. Deep learning was trained using raw and quantitative polar maps and evaluated for prediction of obstructive stenosis in a stratified 10-fold cross-validation procedure. A total of 1,018 (62%) patients and 1,797 of 4,914 (37%) arteries had obstructive disease. Area under the receiver-operating characteristic curve for disease prediction by deep learning was higher than for TPD (per patient: 0.80 vs. 0.78; per vessel: 0.76 vs. 0.73: p < 0.01). With deep learning threshold set to the same specificity as TPD, per-patient sensitivity improved from 79.8% (TPD) to 82.3% (deep learning) (p < 0.05), and per-vessel sensitivity improved from 64.4% (TPD) to 69.8% (deep learning) (p < 0.01). Deep learning has the potential to improve automatic interpretation of MPI as compared with current clinical methods. Copyright © 2018 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.

[Anatomical study and clinical application of a leg flap pedicle-included with cutaneous nerve and its concomitant vessels].

PubMed

Liu, B; Hao, X; Goan, M

2000-05-01

To investigate the blood supply patterns and the clinical liability of a leg flap pedicle-included with cutaneous nerve and its concomitant vessels. Fresh cadaver legs with thirty-two in infants and two in adults were anatomically examined after the intravenous injection of the red Chlorinated Poly Vingl Choride (CPVC). Five patients with the soft tissue defects were selected for the treatment with the flap pedicle-included with the cutaneous nerve and its concomitant vessels. Four main cutaneous nerves were found in the leg after they perforated the deep fascia out. They were companioned with their concomitant vessels with different blood-supply pateeerns, which the upper part of the leg was in an axial pattern and the lower part was in a "chain-type anastomosing" pattern. Following the above-mentioned findings, five cases were successfully treated with this led flap. The leg flap should be designed along the cutaneous nerve and its concomitant vessels. When the flap is applied in the area of blood supply with "chain-type anastomosing" pattern, the deep fascia should also be included in the flap.

Resequencing of the common marmoset genome improves genome assemblies and gene-coding sequence analysis.

PubMed

Sato, Kengo; Kuroki, Yoko; Kumita, Wakako; Fujiyama, Asao; Toyoda, Atsushi; Kawai, Jun; Iriki, Atsushi; Sasaki, Erika; Okano, Hideyuki; Sakakibara, Yasubumi

2015-11-20

The first draft of the common marmoset (Callithrix jacchus) genome was published by the Marmoset Genome Sequencing and Analysis Consortium. The draft was based on whole-genome shotgun sequencing, and the current assembly version is Callithrix_jacches-3.2.1, but there still exist 187,214 undetermined gap regions and supercontigs and relatively short contigs that are unmapped to chromosomes in the draft genome. We performed resequencing and assembly of the genome of common marmoset by deep sequencing with high-throughput sequencing technology. Several different sequence runs using Illumina sequencing platforms were executed, and 181 Gbp of high-quality bases including mate-pairs with long insert lengths of 3, 8, 20, and 40 Kbp were obtained, that is, approximately 60× coverage. The resequencing significantly improved the MGSAC draft genome sequence. The N50 of the contigs, which is a statistical measure used to evaluate assembly quality, doubled. As a result, 51% of the contigs (total length: 299 Mbp) that were unmapped to chromosomes in the MGSAC draft were merged with chromosomal contigs, and the improved genome sequence helped to detect 5,288 new genes that are homologous to human cDNAs and the gaps in 5,187 transcripts of the Ensembl gene annotations were completely filled.

Port Needs Study (Vessel Traffic Services Benefits) Volume III

DOT National Transportation Integrated Search

1991-08-01

This study documents the benefits and costs of potential U.S. Coast Guard Vessel : Traffic Services (VTS) in selected U.S. deep water ports on the Atlantic, Gulf and : Pacific Coasts. The U.S. Department of Transportation's Research and Special Progr...

Bleeding during gonioscopy after deep sclerectomy.

PubMed

Moreno-Montañés, Javier; Rodríguez-Conde, Rosa

2003-10-01

To show a new complication after deep sclerectomy (DS). We described two eyes of two patients with open-angle glaucoma and cataract who were operated on of an uneventful phacoemulsification and DS with SK-gel implantation. Bleeding during gonioscopic examination occurred in both eyes 7 and 8 months after combined surgery. The blood originated from the vessels around the Descemet window, and was probably due to manipulation or rocking of the goniolens. Pressure was immediately applied to the gonioscopic lens and the hyphema was interrupted. These cases show the presence of new vessels around the Descemet window after DS with SK-gel. Bleeding from the Descemet window vessels can occur during gonioscopy even months after DS. We recommend conducting a careful gonioscopic examination in patients who have undergone DS to avoid this complication.

Comparison of Mount Saint Helens Volcanic Eruption to a Nuclear Explosion.

DTIC Science & Technology

1981-01-01

River to deep-draft ships. The volcano ejected materials for a relatively long period of time--the only tiltmeter that survived the eruption showed...shown because they are not standard microbarograph re- cordings. The sensor includes a high-pass electronic filter so that the output must be

29 CFR 1918.2 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-07-01

... content of less than 19.5 percent or greater than 23 percent. Intermodal container means a reusable cargo... does not include ship shaped or deep draft barges. Bulling means the horizontal dragging of cargo across a surface with none of the weight of the cargo supported by the fall. Danger zone means any place...

29 CFR 1918.2 - Definitions.

Code of Federal Regulations, 2013 CFR

2013-07-01

... content of less than 19.5 percent or greater than 23 percent. Intermodal container means a reusable cargo... does not include ship shaped or deep draft barges. Bulling means the horizontal dragging of cargo across a surface with none of the weight of the cargo supported by the fall. Danger zone means any place...

29 CFR 1918.2 - Definitions.

Code of Federal Regulations, 2014 CFR

2014-07-01

... content of less than 19.5 percent or greater than 23 percent. Intermodal container means a reusable cargo... does not include ship shaped or deep draft barges. Bulling means the horizontal dragging of cargo across a surface with none of the weight of the cargo supported by the fall. Danger zone means any place...

Measuring the Impact of Port of Charleston Activities on Local Air Quality

EPA Science Inventory

Ports are a critical feature of the nation’s economy; port commerce supports 13 million jobs and contributes $3.15 trillion to the economy. The value of goods shipped through seaports represents 11% of the GDP. The US has 360 commercial ports, including 150 deep-draft seaports....

76 FR 50187 - Intent To Prepare a Draft Environmental Impact Statement (DEIS) for a Study on the Feasibility of...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-12

...., Charleston, SC 29403. To submit comments please see our Web site at: http://www.sac.usace.army.mil/?action... container traffic and cargo value. In 2009, the Charleston port district was ranked ninth (out of 200 deep... [[Page 50188

SWEPT-SOURCE OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY REVEALS INTERNAL LIMITING MEMBRANE PEELING ALTERS DEEP RETINAL VASCULATURE.

PubMed

Michalewska, Zofia; Nawrocki, Jerzy

2018-04-30

To describe morphology of retinal and choroidal vessels in swept-source optical coherence tomography angiography before and after vitrectomy with the temporal inverted internal limiting membrane (ILM) flap technique for full-thickness macular holes. Prospective, observational study of 36 eyes of 33 patients with full-thickness macular holes swept-source optical coherence tomography angiography was performed in patients before and 1 month after vitrectomy. Vitrectomy with the temporal inverted ILM flap technique was performed. In this method, ILM is peeled only at one side of the fovea. An ILM flap is created to cover the macular hole. Comparison of retina vasculature in the areas of ILM peeling vs. no ILM peeling at 1 and 3 months after successful vitrectomy was performed. The study demonstrated lower density of vessels in the deep retinal plexus in the area where ILM was peeled as compared to the rest of the fovea. Visual acuity and central retinal thickness 1 month after surgery correlates with fovea avascular zone diameter in deep retinal layers at the same time point (P = 0.001). This study confirmed that ILM peeling might alter blood flow in deep retinal vessels below the peeling area in the early postoperative period. The area of the fovea avascular zone corresponds to functional results at the same time point.

Muscle-splitting approach to superior and inferior gluteal vessels: versatile source of recipient vessels for free-tissue transfer to sacral, gluteal, and ischial regions.

PubMed

Park, S

2000-07-01

The superior gluteal vessel has been reported as a recipient in free-tissue transfer for the coverage of complex soft-tissue defects in the lumbosacral region, where a suitable recipient vessel is difficult to find. The characteristics of proximity, vessel caliber, and constancy make the superior gluteal vessel preferable to previously reported recipient vessels. However, there are technical difficulties in microsurgery (e.g., short pedicle length and deep location) and muscle injury (transection of the muscle) associated with use of the superior gluteal vessel. The purpose of this article is to present a modification of an approach to the gluteal vessel to alleviate technical difficulties and minimize muscle injury. From August of 1997 to January of 1999, six patients received microvascular transfer of the latissimus dorsi muscle or myocutaneous flap to the sacral (4) and ischial (2) regions. The causes of defects were tumor (1), trauma (1), and pressure sores (4). A muscle-splitting approach was used on the superior gluteal vessel and was later applied to the inferior gluteal vessel. The gluteus maximus muscle was split as needed in the direction of its fibers, and the perforators were dissected down to the superior or inferior gluteal artery and vein deep into the muscle. The follow-up period ranged from 6 to 22 months, and all of the flaps survived with complete recovery of the lesion. The major drawbacks of using the superior and inferior gluteal vessels can be overcome with the muscle-splitting approach, which provides increased accessibility and additional length to the vascular pedicle while causing minimal injury to the muscle itself. It also proves to be an easy, safe, and reliable method of dissection. When free-tissue transfer to sacral, gluteal, and ischial regions is indicated, the muscle-splitting approach to the superior and inferior gluteal vessels is a recommended option in the selection of a recipient vessel.

50 CFR 648.6 - Dealer/processor permits.

Code of Federal Regulations, 2010 CFR

2010-10-01

... herring, Atlantic sea scallop, Atlantic deep-sea red crab, spiny dogfish, summer flounder, Atlantic surf... permitted vessel of the United States. (ii) Atlantic herring at-sea processing permit. A vessel of the... eligible to obtain an Atlantic herring at-sea processing permit to receive and process Atlantic herring...

33 CFR 165.T09-1080 - Safety Zone and Regulated Navigation Area, Chicago Sanitary and Ship Canal, Romeoville, IL.

Code of Federal Regulations, 2010 CFR

2010-07-01

... vessels are prohibited from transiting the safety zone with any non-potable water on board if they intend to release that water in any form within, or on the other side of the safety zone. Non-potable water includes but is not limited to any water taken on board to control or maintain trim, draft, stability or...

33 CFR 165.T09-1054 - Safety Zone and Regulated Navigation Area, Chicago Sanitary and Ship Canal, Romeoville, IL.

Code of Federal Regulations, 2011 CFR

2011-07-01

... safety zone with any non-potable water on board if they intend to release that water in any form within, or on the other side of the safety zone. Non-potable water includes but is not limited to any water taken on board to control or maintain trim, draft, stability or stresses of the vessel, or taken on...

Could the United States Afford to Lose a Major Port?

DTIC Science & Technology

2013-12-13

Diving TEU Twenty-Foot Equivalent Units TRIA Terrorism Risk Insurance Act TSA Transportation Security Administration ULCC Ultra Large Crude...harbor or port. The United States Navy Office of the Supervisor of Salvage and Diving (SupSalv) directed the National Academies’ Marine Board...shipping vessels might be able to navigate around the wreck if they have a shallow enough draft. This research will investigate how long these

33 CFR 207.249 - Ouachita and Black Rivers, Ark. and La., Mile 0.0 to Mile 338.0 (Camden, Ark.) above the mouth of...

Code of Federal Regulations, 2011 CFR

2011-07-01

..., DEPARTMENT OF THE ARMY, DEPARTMENT OF DEFENSE NAVIGATION REGULATIONS § 207.249 Ouachita and Black Rivers, Ark... draft of at least 2 feet less than the depth over sills, or which have projections liable to damage... concerning depth over sills may be obtained from the lockman on duty. (iii) Vessels having chains, lines, or...

Deep intracerebral (basal ganglia) haematomas in fatal non-missile head injury in man.

PubMed Central

Adams, J H; Doyle, D; Graham, D I; Lawrence, A E; McLellan, D R

1986-01-01

Deep intracerebral (basal ganglia) haematomas were found post mortem in 63 of 635 fatal non-missile head injuries. In patients with a basal ganglia haematoma, contusions were more severe, there was a reduced incidence of a lucid interval, and there was an increased incidence of road traffic accidents, gliding contusions and diffuse axonal injury than in patients without this type of haematoma. Intracranial haematoma is usually thought to be a secondary event, that is a complication of the original injury, but these results suggest that a deep intracerebral haematoma is a primary event. If a deep intracerebral haematoma is identified on an early CT scan it is likely that the patient has sustained severe diffuse brain damage at the time of injury. In the majority of head injuries damage to blood vessels or axons predominates. In patients with a traumatic deep intracerebral haematoma, it would appear that the deceleration/acceleration forces are such that both axons and blood vessels within the brain are damaged at the time of injury. Images PMID:3760892

Intrascleral outflow after deep sclerectomy with absorbable and non-absorbable implants in the rabbit eye.

PubMed

Kałużny, Jakub J; Grzanka, Dariusz; Wiśniewska, Halina; Niewińska, Alicja; Kałużny, Bartłomiej J; Grzanka, Alina

2012-10-01

The purpose of the study is an analysis of intrascleral drainage vessels formed in rabbits' eyes after non-penetrating deep sclerectomy (NPDS) with absorbable and non-absorbable implants, and comparison to eyes in which surgery was performed without implanted material. NPDS was carried out in 12 rabbits, with implantation of non-absorbable methacrylic hydrogel (N=10 eyes) or absorbable cross-linked sodium hyaluronate (N=6 eyes), or without any implant (N=8 eyes). All the animals were euthanized 1 year after surgery. Twenty-one eyeballs were prepared for light microscopy and 3 were prepared for transmission electron microscope (TEM) analysis. Aqueous humour pathways were stained with ferritin in 6 eyeballs. By light microscopy, small vessels adjacent to the areas of scarring were the most common abnormality. Vessel density was significantly higher in operated sclera compared to normal, healthy tissue, regardless of the type of implant used. The average vessel densities were 2.18±1.48 vessels/mm2 in non-implanted sclera, 2.34±1.69 vessels/mm2 in eyes with absorbable implants, and 3.64±1.78 vessels/mm2 in eyes with non-absorbable implants. Analysis of iron distribution in ferritin-injected eyes showed a positive reaction inside new aqueous draining vessels in all groups. TEM analysis showed that the ultrastructure of new vessels matched the features of the small veins. Aqueous outflow after NPDS can be achieved through the newly formed network of small intrascleral veins. Use of non-absorbable implants significantly increases vessel density in the sclera adjacent to implanted material compared to eyes in which absorbable implants or no implants were used.

Noninvasive treatment of deep venous thrombosis using pulsed ultrasound cavitation therapy (histotripsy) in a porcine model.

PubMed

Maxwell, Adam D; Owens, Gabe; Gurm, Hitinder S; Ives, Kimberly; Myers, Daniel D; Xu, Zhen

2011-03-01

This study evaluated histotripsy as a noninvasive, image-guided method of thrombolysis in a porcine model of deep vein thrombosis. Histotripsy therapy uses short, high-intensity, focused ultrasound pulses to cause mechanical breakdown of targeted soft tissue by acoustic cavitation, which is guided by real-time ultrasound imaging. This is an in vivo feasibility study of histotripsy thrombolysis. Acute thrombi were formed in the femoral vein of juvenile pigs weighing 30-40 kg by balloon occlusion with two catheters and thrombin infusion. A 10-cm-diameter 1-MHz focused transducer was used for therapy. An 8-MHz ultrasound imager was used to align the clot with the therapy focus. Therapy consisted of five cycle pulses delivered at a rate of 1 kHz and peak negative pressure between 14 and 19 MPa. The focus was scanned along the long axis of the vessel to treat the entire visible clot during ultrasound exposure. The targeted region identified by a hyperechoic cavitation bubble cloud was visualized via ultrasound during treatment. Thrombus breakdown was apparent as a decrease in echogenicity within the vessel in 10 of 12 cases and in 7 cases improved flow through the vein as measured by color Doppler. Vessel histology found denudation of vascular endothelium and small pockets of hemorrhage in the vessel adventitia and underlying muscle and fatty tissue, but perforation of the vessel wall was never observed. The results indicate histotripsy has potential for development as a noninvasive treatment for deep vein thrombosis. Copyright © 2011 SIR. Published by Elsevier Inc. All rights reserved.

Geology and structure of the Pine River, Florida River, Carbon Junction, and Basin Creek gas seeps, La Plata County, Colorado

USGS Publications Warehouse

Fassett, James E.; Condon, Steven M.; Huffman, A. Curtis; Taylor, David J.

1997-01-01

Introduction: This study was commissioned by a consortium consisting of the Bureau of Land Management, Durango Office; the Colorado Oil and Gas Conservation Commission; La Plata County; and all of the major gas-producing companies operating in La Plata County, Colorado. The gas-seep study project consisted of four parts; 1) detailed surface mapping of Fruitland Formation coal outcrops in the above listed seep areas, 2) detailed measurement of joint and fracture patterns in the seep areas, 3) detailed coal-bed correlation of Fruitland coals in the subsurface adjacent to the seep areas, and 4) studies of deep-seated seismic patterns in those seep areas where seismic data was available. This report is divided into three chapters labeled 1, 2, and 3. Chapter 1 contains the results of the subsurface coal-bed correla-tion study, chapter 2 contains the results of the surface geologic mapping and joint measurement study, and chapter 3, contains the results of the deep-seismic study. A preliminary draft of this report was submitted to the La Plata County Group in September 1996. All of the members of the La Plata Group were given an opportunity to critically review the draft report and their comments were the basis for revising the first draft to create this final version of a geologic report on the major La Plata County gas seeps located north of the Southern Ute Indian Reservation.

Endothelial Snail Regulates Capillary Branching Morphogenesis via Vascular Endothelial Growth Factor Receptor 3 Expression

PubMed Central

Park, Jeong Ae; Kim, Dong Young; Kim, Young-Myeong; Kwon, Young-Guen

2015-01-01

Vascular branching morphogenesis is activated and maintained by several signaling pathways. Among them, vascular endothelial growth factor receptor 2 (VEGFR2) signaling is largely presented in arteries, and VEGFR3 signaling is in veins and capillaries. Recent reports have documented that Snail, a well-known epithelial-to-mesenchymal transition protein, is expressed in endothelial cells, where it regulates sprouting angiogenesis and embryonic vascular development. Here, we identified Snail as a regulator of VEGFR3 expression during capillary branching morphogenesis. Snail was dramatically upregulated in sprouting vessels in the developing retinal vasculature, including the leading-edged vessels and vertical sprouting vessels for capillary extension toward the deep retina. Results from in vitro functional studies demonstrate that Snail expression colocalized with VEGFR3 and upregulated VEGFR3 mRNA by directly binding to the VEGFR3 promoter via cooperating with early growth response protein-1. Snail knockdown in postnatal mice attenuated the formation of the deep capillary plexus, not only by impairing vertical sprouting vessels but also by downregulating VEGFR3 expression. Collectively, these data suggest that the Snail-VEGFR3 axis controls capillary extension, especially in vessels expressing VEGFR2 at low levels. PMID:26147525

Thermophysiological responses and work strain in fishermen on deep-sea fishing vessels.

PubMed

Høye, Erik Ulvolden; Sandsund, Mariann; Heidelberg, Cecilie Thon; Aasmoe, Lisbeth; Reinertsen, Randi Eidsmo

2016-01-01

Fishermen working on deep-sea vessels in the Barents and Norwegian Sea are exposed to low air temperatures, strong winds, high humidity, rain, snow and work at different intensities. Few studies have investigated the effect of environmental work factors on the physiology of this occupational group. The aim of the study was to investigate work strain and thermophysiological responses of fishermen on the trawl and factory decks of deep-sea vessels. Twenty-five professional male fishermen (age 39 ± 13 years) were recruited to the study which was performed on three trawlers in the Norwegian Sea in April, June and August 2014. During a six-hour shift, heart rate (HR), core (Tc) and mean skin (Ts) temperatures were recorded, and questions about subjective thermal sensation and comfort were answered. Short periods of hard (above 86% of HRmax) work raised Tc by 0.8°C to 37.8°C and decreased Ts by 2.3°C to 29.8°C during work on the trawl deck, and subjects reported being warm and sweaty. On the factory deck long periods of fairly light (between 52% and 66% HRmax) work, Tc of 37.4°C and Ts of 30.9°C were measured. Fishermen experience intermittent periods of heavy work on the trawl deck shown with elevated core temperature and HR. Work on the factory deck includes long periods of repetitive work with light to moderate work strain. A better understanding of work strain and environmental challenges during work on Norwegian deep-sea vessels will help identify exposure risks during work in the cold and heat.

50 CFR 648.262 - Accountability measures for red crab limited access vessels.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 50 Wildlife and Fisheries 10 2011-10-01 2011-10-01 false Accountability measures for red crab... UNITED STATES Management Measures for the Atlantic Deep-Sea Red Crab Fishery § 648.262 Accountability measures for red crab limited access vessels. (a) Closure authority. NMFS shall close the EEZ to fishing...

33 CFR 164.35 - Equipment: All vessels.

Code of Federal Regulations, 2013 CFR

2013-07-01

...: (i) Calm weather—wind 10 knots or less, calm sea; (ii) No current; (iii) Deep water conditions—water...: (1) Calm weather—wind 10 knots or less, calm sea; (2) No current; (3) Water depth twice the vessel's..., permanently displayed on the navigating bridge and in the steering gear compartment. (l) An indicator readable...

33 CFR 164.35 - Equipment: All vessels.

Code of Federal Regulations, 2014 CFR

2014-07-01

...: (i) Calm weather—wind 10 knots or less, calm sea; (ii) No current; (iii) Deep water conditions—water...: (1) Calm weather—wind 10 knots or less, calm sea; (2) No current; (3) Water depth twice the vessel's..., permanently displayed on the navigating bridge and in the steering gear compartment. (l) An indicator readable...

15 CFR 970.801 - Criteria for safety of life and property at sea.

Code of Federal Regulations, 2010 CFR

2010-01-01

... REGULATIONS OF THE ENVIRONMENTAL DATA SERVICE DEEP SEABED MINING REGULATIONS FOR EXPLORATION LICENSES Safety... inspection statutes pertaining to United States flag vessels are: 46 U.S.C. 86 (Loadlines); 46 U.S.C. 395... hire). All United States flag vessels will be required to meet existing regulatory requirements...

33 CFR 164.35 - Equipment: All vessels.

Code of Federal Regulations, 2010 CFR

2010-07-01

... to alter course 90 degrees with maximum rudder angle and constant power settings, for either full and...: (i) Calm weather—wind 10 knots or less, calm sea; (ii) No current; (iii) Deep water conditions—water...: (1) Calm weather—wind 10 knots or less, calm sea; (2) No current; (3) Water depth twice the vessel's...

33 CFR 164.35 - Equipment: All vessels.

Code of Federal Regulations, 2011 CFR

2011-07-01

... to alter course 90 degrees with maximum rudder angle and constant power settings, for either full and...: (i) Calm weather—wind 10 knots or less, calm sea; (ii) No current; (iii) Deep water conditions—water...: (1) Calm weather—wind 10 knots or less, calm sea; (2) No current; (3) Water depth twice the vessel's...

78 FR 29336 - Intent To Prepare an Environmental Impact Statement for Arctic Deep Draft Ports Navigation...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-20

... vicinity of Nome is not adequate to accommodate the need for an efficient and safe harbor appropriate to... Transportation is working with the U. S. Army Corps of Engineers in investigating the need for expanding the... encounter the haphazard navigation scenario that presently exists in a challenging maritime environment...

Effect of prolonged hypokinesia on resistance of resistive vessels in rats

NASA Technical Reports Server (NTRS)

Saltykova, V. A.

1982-01-01

Under the effect of prolonged hypokinesia, the perfusion pressure in resistive vessels, measured under conditions of deep anesthesia and complete denervation, increased by approximately the same degree as arterial pressure in non-anesthetized animals. The increase in arterial, perfusion pressure and the resistance of resistive vessels in animals subjected to prolonged hypokinesia was accompanied by an increase in adrenoreactivity. During prolonged hypokinesia, partial obliteration of the vascular bed of the skeletal muscles plays a significant role in the observed increase in resistance of vessels of the extremities. The increase in adrenoreactivity of the vessels during hypokinesia may be realized as a partial case of an increase in the adrenoreactivity of structures whose innervation is disturbed.

Successful Deep Inferior Epigastric Perforator Flap Harvest despite Preoperative Therapeutic Subcutaneous Heparin Administration into the Abdominal Pannus.

PubMed

Duncumb, Joseph W; Miyagi, Kana; Forouhi, Parto; Malata, Charles M

2016-01-01

Abdominal free flaps for microsurgical breast reconstruction are most commonly harvested based on the deep inferior epigastric vessels that supply skin and fat via perforators through the rectus muscle and sheath. Intact perforator anatomy and connections are vital for subsequent optimal flap perfusion and avoidance of necrosis, be it partial or total. The intraflap vessels are delicate and easily damaged and it is generally advised that patients should avoid heparin injection into the abdominal pannus preoperatively as this may compromise the vascular perforators through direct needle laceration, pressure from bruising, haematoma formation, or perforator thrombosis secondary to external compression. We report three cases of successful deep inferior epigastric perforator (DIEP) flap harvest despite patients injecting therapeutic doses of low molecular weight heparin into their abdomens for thrombosed central venous lines (portacaths™) used for administering primary chemotherapy in breast cancer.

Successful Deep Inferior Epigastric Perforator Flap Harvest despite Preoperative Therapeutic Subcutaneous Heparin Administration into the Abdominal Pannus

PubMed Central

Miyagi, Kana; Forouhi, Parto

2016-01-01

Abdominal free flaps for microsurgical breast reconstruction are most commonly harvested based on the deep inferior epigastric vessels that supply skin and fat via perforators through the rectus muscle and sheath. Intact perforator anatomy and connections are vital for subsequent optimal flap perfusion and avoidance of necrosis, be it partial or total. The intraflap vessels are delicate and easily damaged and it is generally advised that patients should avoid heparin injection into the abdominal pannus preoperatively as this may compromise the vascular perforators through direct needle laceration, pressure from bruising, haematoma formation, or perforator thrombosis secondary to external compression. We report three cases of successful deep inferior epigastric perforator (DIEP) flap harvest despite patients injecting therapeutic doses of low molecular weight heparin into their abdomens for thrombosed central venous lines (portacaths™) used for administering primary chemotherapy in breast cancer. PMID:27651974

Development of Yield and Tensile Strength Design Curves for Alloy 617

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nancy Lybeck; T. -L. Sham

2013-10-01

The U.S. Department of Energy Very High Temperature Reactor Program is acquiring data in preparation for developing an Alloy 617 Code Case for inclusion in the nuclear section of the American Society of Mechanical Engineers (ASME) Boiler and Pressure Vessel (B&PV) Code. A draft code case was previously developed, but effort was suspended before acceptance by ASME. As part of the draft code case effort, a database was compiled of yield and tensile strength data from tests performed in air. Yield strength and tensile strength at temperature are used to set time independent allowable stress for construction materials in B&PVmore » Code, Section III, Subsection NH. The yield and tensile strength data used for the draft code case has been augmented with additional data generated by Idaho National Laboratory and Oak Ridge National Laboratory in the U.S. and CEA in France. The standard ASME Section II procedure for generating yield and tensile strength at temperature is presented, along with alternate methods that accommodate the change in temperature trends seen at high temperatures, resulting in a more consistent design margin over the temperature range of interest.« less

Technical Letter Report Development of Flaw Size Distribution Tables Including Effects of Flaw Depth Sizing Errors for Draft 10CFR 50.61a (Alternate PTS Rule) JCN-N6398, Task 4

DOE Office of Scientific and Technical Information (OSTI.GOV)

Simonen, Fredric A.; Gosselin, Stephen R.; Doctor, Steven R.

2013-04-22

This document describes a new method to determine whether the flaws in a particular reactor pressure vessel are consistent with the assumptions regarding the number and sizes of flaws used in the analyses that formed the technical justification basis for the new voluntary alternative Pressurized Thermal Shock (PTS) rule (Draft 10 CFR 50.61a). The new methodology addresses concerns regarding prior methodology because ASME Code Section XI examinations do not detect all fabrication flaws, they have higher detection performance for some flaw types, and there are flaw sizing errors always present (e.g., significant oversizing of small flaws and systematic under sizingmore » of larger flaws). The new methodology allows direct comparison of ASME Code Section XI examination results with values in the PTS draft rule Tables 2 and 3 in order to determine if the number and sizes of flaws detected by an ASME Code Section XI examination are consistent with those assumed in the probabilistic fracture mechanics calculations performed in support of the development of 10 CFR 50.61a.« less

Project Cheesebox: a Journey into History. Volume 1

DTIC Science & Technology

1974-12-01

china and drapes . 89 In addition, the builders were also to provide "masts, spars, sails and rigging of sufficient dimensions to drive the vessel...plate iron 3/8 innh thick with a 4 inch angle iron rivetted at the top extending all round the vessel. A plate iron armour 5 feet deep, 6 inches...thick is firmly bolted to the outside of the wooden bulwark extending all round the upper vessel. This armour is composed of six thicknesses of plate

Winter Fish Populations in Probable Locations of Air Bubblers in the St. Marys River-Lake Superior Area

DTIC Science & Technology

1980-09-01

Lawrence Seaway Navigation Season Extension, Draft Main Report and Environmental Statement. Detroit, Michigan. Potential effects on fish were discussed...to keep channels ice free for winter vessel passage. The stucies were Jone to determine base line ecological conditions and the effects of the...Subjects were: "Ecological effects of air bub- blers in the winter, a partially annotated bibliography" and "Annotated bibliography on winter fish and

50 CFR 660.116 - Trawl fishery-observer requirements.

Code of Federal Regulations, 2010 CFR

2010-10-01

...-sea processing vessels. The observer sampling station must include a table at least 0.6 m deep, 1.2 m... at sea must carry one NMFS-certified observer, from the time the vessel leaves port on a trip in which the catch is sorted at sea to the time that all catch from that trip has been offloaded. (2...

Passive filtration of air egressing from nuclear containment

DOE Office of Scientific and Technical Information (OSTI.GOV)

Malloy, III, John D

2017-09-26

A nuclear reactor includes a reactor core comprising fissile material disposed in a reactor pressure vessel. A radiological containment contains the nuclear reactor. A containment compartment contains the radiological containment. A heat sink includes a chimney configured to develop an upward-flowing draft in response to heated fluid flowing into a lower portion of the chimney. A fluid conduit is arranged to receive fluid from the containment compartment and to discharge into the chimney. A filter may be provided, with the fluid conduit including a first fluid conduit arranged to receive fluid from the containment compartment and to discharge into anmore » inlet of the filter, and a second fluid conduit arranged to receive fluid from an outlet of the filter and to discharge into the chimney. As the draft is developed passively, there is no need for a blower or pump configured to move fluid through the fluid conduit.« less

Scanning the Horizon: Coast Guard Strategy in a Hot, Flat, Crowded World

DTIC Science & Technology

2010-03-12

Mexico. From 1992 to 2007, deepwater offshore rigs drilling in deep water in the Gulf of Mexico increased from three to 30, and deepwater oil production...discusses the Coast Guard’s Integrated Deepwater System program, which includes recapitalization of its deep-water vessels and aircraft.89 At the...water and ultra deep water drilling. Discussion of increased outer continental shelf activity in higher level strategic planning indicates that

Hazards of deep-sea fishing1

PubMed Central

Schilling, R. S. F.

1971-01-01

Schilling, R. S. F. (1971). Brit. J. industr. Med., 28, 27-35. Hazards of deep-sea fishing. During the nineteenth century sailing smacks suffered heavy losses at sea. Their replacement by steam trawlers and motor vessels reduced casualties to both ships and men. The accident mortality of fishermen in England and Wales has been grossly underestimated by the Registrar General of Births and Deaths because all but a few deaths at sea are reported separately to the Registrar General of Shipping and Seamen and are not taken into account in calculating mortality rates. By including deaths at sea in the period 1959-63, fishermen's standardized mortality ratio for accidents is increased from 466 to 1 726. Between 1958 and 1967, 92 fishermen on British trawlers lost their lives as a result of casualties to vessels; and 116 from individual accidents, mostly by drowning. The importance of individual accidents is emphasized by the fact that in years when ther was no heavy loss of life from vessel casualties, fishermen's fatal accident rates were at least twice those of coal miners and more than 20 times the rate of men in manufacturing industries. Crews of distant-water vessels have higher fatal accident rates than crews of near- and middle-water vessels (2·3 against 1·8 per 1 000 man-years); for skippers and mates on distant-water vessels the rate is 3·2 per 1 000 man-years which is higher than the corresponding rate of 2·6 for deck-hands and almost double that for other crew members. In 47 out of 90 trawlers lost or serioulsy damaged, the cause of the casualty was attributable to negligent navigation. Fatigue due to excessively long hours of work may contribute to casualties to both vessels and individuals. The Committee of Inquiry into Trawler Safety set up by the British Government after the loss of three trawlers in 1968 made many recommendations for higher standards of design, construction, and stability of vessels for the deep-sea fleet and for a reduction in the hours of work for deck-hands. The Committee also recommended the supply of a support ship at sea offering special services such as weather forecasting, medical and technical aid, and the provision of occupational health services for fishermen in port. PMID:5101166

Five Hundred and Seventy Three Holes in the Bottom of the Sea-Some Results From Seven Years of Deep-Sea Drilling

ERIC Educational Resources Information Center

Davies, T. A.

1976-01-01

Described are the background, operation, and findings of the work of the deep sea drilling vessel Glomar Challenger, which has taken 8,638 core samples from 573 holes at 392 sites on the floor of the Earth's oceans. (SL)

Freshwater Export from the Arctic Ocean and its Downstream Effect on Labrador Sea Deep Convection in a High-Resolution Numerical Model

DTIC Science & Technology

2010-12-01

Arctic has been observed in the northern Canadian Arctic Archipelago ( Bourke and McLaren 1992). There, thick multiyear ice of Arctic origin encounters...Affairs, 87(2), 63-77. 172 Bourke , R. H., and A. S. McLaren, 1992: Contour mapping of Arctic Basin ice draft and roughness parameters. J. Geophys

Genome Sequence of Thalassospira profundimaris Type Strain WP0211

PubMed Central

Lai, Qiliang

2012-01-01

Thalassospira profundimaris WP0211T was isolated from a pyrene-degrading consortium, enriched from deep-sea sediment collected from the West Pacific Ocean. Here, we present the draft genome of strain WP0211T, which contains 4,380,232 bp with a G+C content of 55.19% and contains 4,040 protein-coding genes and 45 tRNAs. PMID:23209215

Genome sequence of Thalassospira profundimaris type strain WP0211.

PubMed

Lai, Qiliang; Shao, Zongze

2012-12-01

Thalassospira profundimaris WP0211(T) was isolated from a pyrene-degrading consortium, enriched from deep-sea sediment collected from the West Pacific Ocean. Here, we present the draft genome of strain WP0211(T), which contains 4,380,232 bp with a G+C content of 55.19% and contains 4,040 protein-coding genes and 45 tRNAs.

Pascagoula Harbor, Mississippi, Feasibility Report on Improvement of the Federal Deep-Draft Navigation Channel. Volume 1. Main Report and Environmental Impact Statement.

DTIC Science & Technology

1985-03-01

cerifera) and stands of Cogongrass, locally known as ’Jap Grass’ ( Imperata cylindrica ) and torpedo grass (Panicum repens). The lower southeastern-most...dominated by wax myrtle and sea myrtle with stands of Cogongrass, locally known as ’Jap Grass’ ( Imperata cylindrica ) and torpedo grass (Panicum repens

76 FR 77502 - Intent To Prepare a Draft Environmental Impact Statement Regarding the Wolfpen Knob Development...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-13

... the Clean Water Act, may have related to discharges of dredge and fill material into Waters of the... deep mine, a preparation plant, a refuse disposal site, a water impoundment, and a new rail line. The... water impoundment would provide water for the operation of the preparation plant and dust control at the...

Leadership Development as a Result of Self-Knowledge and Self-Control. (Preliminary Draft).

ERIC Educational Resources Information Center

Holst, Alvin W.

Ineffectiveness in leadership (tyranny) happens because the person does not learn effective ways to satisfy deep and possibly unconscious motives. A person attempting to fulfill the obligations of a leadership position can be very effective if he/she can control his/her personal motives as a part of fulfilling the needs of the position. The person…

Permeability Surface of Deep Middle Cerebral Artery Territory on Computed Tomographic Perfusion Predicts Hemorrhagic Transformation After Stroke.

PubMed

Li, Qiao; Gao, Xinyi; Yao, Zhenwei; Feng, Xiaoyuan; He, Huijin; Xue, Jing; Gao, Peiyi; Yang, Lumeng; Cheng, Xin; Chen, Weijian; Yang, Yunjun

2017-09-01

Permeability surface (PS) on computed tomographic perfusion reflects blood-brain barrier permeability and is related to hemorrhagic transformation (HT). HT of deep middle cerebral artery (MCA) territory can occur after recanalization of proximal large-vessel occlusion. We aimed to determine the relationship between HT and PS of deep MCA territory. We retrospectively reviewed 70 consecutive acute ischemic stroke patients presenting with occlusion of the distal internal carotid artery or M1 segment of the MCA. All patients underwent computed tomographic perfusion within 6 hours after symptom onset. Computed tomographic perfusion data were postprocessed to generate maps of different perfusion parameters. Risk factors were identified for increased deep MCA territory PS. Receiver operating characteristic curve analysis was performed to calculate the optimal PS threshold to predict HT of deep MCA territory. Increased PS was associated with HT of deep MCA territory. After adjustments for age, sex, onset time to computed tomographic perfusion, and baseline National Institutes of Health Stroke Scale, poor collateral status (odds ratio, 7.8; 95% confidence interval, 1.67-37.14; P =0.009) and proximal MCA-M1 occlusion (odds ratio, 4.12; 95% confidence interval, 1.03-16.52; P =0.045) were independently associated with increased deep MCA territory PS. Relative PS most accurately predicted HT of deep MCA territory (area under curve, 0.94; optimal threshold, 2.89). Increased PS can predict HT of deep MCA territory after recanalization therapy for cerebral proximal large-vessel occlusion. Proximal MCA-M1 complete occlusion and distal internal carotid artery occlusion in conjunction with poor collaterals elevate deep MCA territory PS. © 2017 American Heart Association, Inc.

Draft Genome of Scalindua rubra, Obtained from the Interface Above the Discovery Deep Brine in the Red Sea, Sheds Light on Potential Salt Adaptation Strategies in Anammox Bacteria.

PubMed

Speth, Daan R; Lagkouvardos, Ilias; Wang, Yong; Qian, Pei-Yuan; Dutilh, Bas E; Jetten, Mike S M

2017-07-01

Several recent studies have indicated that members of the phylum Planctomycetes are abundantly present at the brine-seawater interface (BSI) above multiple brine pools in the Red Sea. Planctomycetes include bacteria capable of anaerobic ammonium oxidation (anammox). Here, we investigated the possibility of anammox at BSI sites using metagenomic shotgun sequencing of DNA obtained from the BSI above the Discovery Deep brine pool. Analysis of sequencing reads matching the 16S rRNA and hzsA genes confirmed presence of anammox bacteria of the genus Scalindua. Phylogenetic analysis of the 16S rRNA gene indicated that this Scalindua sp. belongs to a distinct group, separate from the anammox bacteria in the seawater column, that contains mostly sequences retrieved from high-salt environments. Using coverage- and composition-based binning, we extracted and assembled the draft genome of the dominant anammox bacterium. Comparative genomic analysis indicated that this Scalindua species uses compatible solutes for osmoadaptation, in contrast to other marine anammox bacteria that likely use a salt-in strategy. We propose the name Candidatus Scalindua rubra for this novel species, alluding to its discovery in the Red Sea.

An improved plating process

NASA Technical Reports Server (NTRS)

Askew, John C.

1994-01-01

An alternative to the immersion process for the electrodeposition of chromium from aqueous solutions on the inside diameter (ID) of long tubes is described. The Vessel Plating Process eliminates the need for deep processing tanks, large volumes of solutions, and associated safety and environmental concerns. Vessel Plating allows the process to be monitored and controlled by computer thus increasing reliability, flexibility and quality. Elimination of the trivalent chromium accumulation normally associated with ID plating is intrinsic to the Vessel Plating Process. The construction and operation of a prototype Vessel Plating Facility with emphasis on materials of construction, engineered and operational safety and a unique system for rinse water recovery are described.

76 FR 39369 - Fisheries of the Northeastern United States; Atlantic Deep-Sea Red Crab Fishery; Amendment 3

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-06

... crab vessels may not deploy parlor traps/pots in water depths greater than 400 meters (219 fathoms... water deeper than 400 m; prohibit a limited access red crab vessel from harvesting red crab in water shallower than 400 m; and prohibit parlor traps from being deployed at water shallower than 400 m. This...

Capital requirements for the transportation of energy materials based on PIES Scenario estimates

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gezen, A.; Kendrick, M.J.; Khan, S.S.

In May 1978, Transportation and Economic Research Associates (TERA), Inc. completed a study in which information and methodologies were developed for the determination of capital requirements in the transportation of energy materials. This work was designed to aid EIA in the analysis of PIES solutions. The work consisted of the development of five algorithms which are used to estimate transportation-investment requirements associated with energy commodities and transportation modes. For the purpose of this analysis, TERA was provided with three PIES-solution scenarios for 1985. These are: Scenario A which assumes a high domestic economic rate of growth along with its correspondingmore » high demand for petroleum, as well as a high domestic supply of petroleum; Scenario C which assumes a medium level of economic growth and petroleum demand and supply; and Scenario E which assumes a low level of economic growth and domestic demand and supply for petroleum. Two PIES-related outputs used in TERA's analysis are the ''COOKIE'' reports which present activity summaries by region and ''PERUSE'' printouts of solution files which give interregional flows by energy material. Only the transportation of four energy materials, crude oil, petroleum products, natural gas, and coal is considered. In estimating the capital costs of new or expanded capacity for the transportation of these materials, three transportation modes were examined: pipelines, water carriers (inland barge and deep draft vessels), and railroads. (MCW)« less

The first perforating branch of the deep femoral artery: A reliable recipient vessel for vascularized fibular grafts: An anatomical study.

PubMed

Sur, Yoo Joon; Morsy, Mohamed; Mohan, Anita T; Zhu, Lin; Lachman, Nirusha; Saint-Cyr, Michel

2016-03-01

Although the perforating branches of the deep femoral artery have been introduced as recipient vessels for vascularized fibular grafts in the treatment of osteonecrosis of the femoral head, comprehensive knowledge of the related anatomy is deficient. The aims of this study were to provide detailed anatomical data for the perforating branches of the deep femoral artery and validate their usefulness as recipient vessels for vascularized fibular grafts. Anatomical dissection was performed on 11 fresh human cadaveric lower extremities. The number, locations, and diameters of the perforating branches were documented. The topographic relationships with the vastus ridge and the tendinous insertion of the gluteus maximus were clarified. The diameters of the perforating branches were compared with those of the ascending branch of the lateral circumflex femoral and the peroneal arteries. The mean number of perforating branches was 3.5. The mean distances from the vastus ridge to the first, second, and third perforating branches were 8.1, 13.7, and 20.4 cm, respectively. The first perforating branch was always located medial to the tendinous insertion of the gluteus maximus, whereas the second perforating branch was always located distal to the gluteus maximus. The mean diameters of the first, second, third, and fourth perforating branches were 3.1, 2.3, 1.6, and 1.2 mm, respectively. The mean diameters of the ascending branch of the lateral circumflex femoral and the peroneal arteries were 2.0 and 3.6 mm, respectively. The first perforating branch of the deep femoral artery is an appropriate alternative recipient vessel for vascularized fibular grafts in the treatment of osteonecrosis of the femoral head. It has a very consistent anatomy with a suitable location and diameter for anastomosis of the peroneal artery. Copyright © 2015 British Association of Plastic, Reconstructive and Aesthetic Surgeons. Published by Elsevier Ltd. All rights reserved.

Phase I General Design Memorandum with Environmental Impact Statement. A Harbor for Light-Draft Vessels at Cross Village, Michigan

DTIC Science & Technology

1981-07-01

proposed boat harbor at Cross Village, Emmet County, Michigan. A The Bald Eagle (Haliaeetus leucocephalus) and the Longjaw Ciaco (Co2Ronus_ alpenae ...of 11.0 percent following harbor completion. Alpena is nearby (approx. 35 miles), with a population of approximately 15,000. This could possibly...encourage people to move to the Harrisville area since Alpena would supply their major shopping, entertainment and service needs. St. James, Arcadia, and

AIS Modeling and a Satellite for AIS Observations in the High North + Draft New ITU-R Report Improved Satellite Detection of AIS

DTIC Science & Technology

2008-09-01

20 Aug 08) Report Documentation Page Form ApprovedOMB No . 0704-0188 Public reporting burden for the collection of information is estimated to average...Jefferson Davis Highway, Suite 1204, Arlington VA 22202-4302. Respondents should be aware that notwithstanding any other provision of law, no person...to eliminate propagation delay – 3 min. reporting interval to lower message rate • Vessel consequences: – No extra hardware – Transponder software

Automated segmentation of geographic atrophy using deep convolutional neural networks

NASA Astrophysics Data System (ADS)

Hu, Zhihong; Wang, Ziyuan; Sadda, SriniVas R.

2018-02-01

Geographic atrophy (GA) is an end-stage manifestation of the advanced age-related macular degeneration (AMD), the leading cause of blindness and visual impairment in developed nations. Techniques to rapidly and precisely detect and quantify GA would appear to be of critical importance in advancing the understanding of its pathogenesis. In this study, we develop an automated supervised classification system using deep convolutional neural networks (CNNs) for segmenting GA in fundus autofluorescene (FAF) images. More specifically, to enhance the contrast of GA relative to the background, we apply the contrast limited adaptive histogram equalization. Blood vessels may cause GA segmentation errors due to similar intensity level to GA. A tensor-voting technique is performed to identify the blood vessels and a vessel inpainting technique is applied to suppress the GA segmentation errors due to the blood vessels. To handle the large variation of GA lesion sizes, three deep CNNs with three varying sized input image patches are applied. Fifty randomly chosen FAF images are obtained from fifty subjects with GA. The algorithm-defined GA regions are compared with manual delineation by a certified grader. A two-fold cross-validation is applied to evaluate the algorithm performance. The mean segmentation accuracy, true positive rate (i.e. sensitivity), true negative rate (i.e. specificity), positive predictive value, false discovery rate, and overlap ratio, between the algorithm- and manually-defined GA regions are 0.97 +/- 0.02, 0.89 +/- 0.08, 0.98 +/- 0.02, 0.87 +/- 0.12, 0.13 +/- 0.12, and 0.79 +/- 0.12 respectively, demonstrating a high level of agreement.

75 FR 34929 - Safety Zones: Neptune Deep Water Port, Atlantic Ocean, Boston, MA

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-21

...-AA00 Safety Zones: Neptune Deep Water Port, Atlantic Ocean, Boston, MA AGENCY: Coast Guard, DHS. ACTION..., Boston, MA; Final Rule (USCG-2009-0589), to protect vessels from the hazard posed by the presence of the... read as follows: Sec. 165.T01-0542 Safety Zones: Neptune Deepwater Port, Atlantic Ocean, Boston, MA. (a...

Where Does the Transplanted Fat is Located in the Gluteal Region? Research Letter.

PubMed

Ramos-Gallardo, Guillermo; Medina-Zamora, Pablo; Cardenas-Camarena, Lázaro; Orozco-Rentería, David; Duran-Vega, Héctor; Mota-Fonseca, Eduardo

2017-12-29

Liposuction is one of the most popular plastic surgery procedures. As in any surgery, there are risks and complications, especially when combined with fat injection. Case reports of fat embolism have been reported. A possible explanation is the puncture and tearing of gluteal vessels during the procedure, especially when a deep injection is planned. To identify the places where fat can be located after injection during a fat graft in the gluteus. An experimental study was done in which colorant was injected in four directions using four different quadrants of the gluteus. We Injected 10 cc six times following clock hands until 60 cc were injected, and the cutaneous flap and the muscles were then elevated. Our main purpose was to describe where the colorant went and if it was in contact with the vessels (superior and inferior gluteal vessels). In total, four gluteus muscles were injected and dissected. Injection in the lower lateral quadrant was mainly into the muscle, and colorant was observed in the hypogastric vessels. The injection in the upper quadrants stayed mainly in the subcutaneous tissue. During surgery, it is important to identify the location of the perforators and to avoid a deep injection, especially from the lower lateral quadrant to the superior medial quadrant (Q4 to Q1), as the probability of puncturing and injecting fat into the main vessels from this direction is higher.

Relaxation Techniques.

DTIC Science & Technology

1985-04-01

Colonel Robert Fowler for sponsoring this project, Major Richard Hartson for diligently editing each draft and the men of ACSC Seminar A-li ( Mix 1...and AWC Seminar 15 ( Mix 1) for encouraging the author to introduce relaxation techniques to other military officers through this videotape. Special...anytime and without having to stop what you’re doing. The individuals were usually surprised at how easily deep breathing initiated a feeling of

78 FR 10163 - Notice of Availability of Draft Section 3116 Basis for Determination for Closure of H Tank Farm...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-13

... isolation in a deep geologic repository for spent fuel or high-level radioactive waste; (2) has had highly... in 10 CFR Part 61, Subpart C and pursuant to a State approved closure plan or State-issued permit; or... with the performance objectives of 10 CFR Part 61, Subpart C; pursuant to a State approved closure plan...

76 FR 60474 - Intent To Prepare a Draft Environmental Impact Statement (DEIS) for the Haile Gold Mine in...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-29

...--County on January 28, 2011. The public notice is available on Charleston District's public Web site at... eight open mining pits over a twelve-year period, with pit depths ranging from 110 to 840 feet deep. The... of January 28, 2011, and are available on Charleston District's public Web site at http://www.sac...

77 FR 44528 - Dry Cargo Residue Discharges in the Great Lakes

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-30

...The Coast Guard proposes replacing its existing interim rule with a new rule to regulate the operation of U.S. and foreign vessels carrying bulk dry cargo such as limestone, iron ore, and coal on the U.S. waters of the Great Lakes, and the operation of U.S. bulk dry cargo vessels anywhere on the Great Lakes. Specifically, the Coast Guard proposes new requirements for the discharge of bulk dry cargo residue (DCR) on the U.S. waters of the Great Lakes. The Coast Guard also announces the availability of the tiered Draft Environmental Impact Statement (DEIS) prepared in support of this proposal. The proposed rule would continue to allow non-hazardous and non-toxic discharges of bulk DCR in limited areas of the Great Lakes. However, vessel owners and operators would need to minimize DCR discharges using methods they would be required to document in DCR management plans. The proposed rule would prohibit limestone and clean stone DCR discharges in some waters where they are now permitted. The proposed rule promotes the Coast Guard's strategic goals of maritime mobility and safety and protection of natural resources.

MRI markers of small vessel disease in lobar and deep hemispheric intracerebral hemorrhage

PubMed Central

Smith, Eric E.; Nandigam, Kaveer R.N.; Chen, Yu-Wei; Jeng, Jed; Salat, David; Halpin, Amy; Frosch, Matthew; Wendell, Lauren; Fazen, Louis; Rosand, Jonathan; Viswanathan, Anand; Greenberg, Steven M.

2014-01-01

Background MRI evidence of small vessel disease is common in intracerebral hemorrhage (ICH). We hypothesized that ICH caused by cerebral amyloid angiopathy (CAA) or hypertensive vasculopathy would have different distributions of MRI T2 white matter hyperintensity (WMH) and microbleeds (MB). Methods Data were analyzed from 133 consecutive patients with primary supratentorial ICH and adequate MRI sequences. CAA was diagnosed using the Boston criteria. WMH segmentation was performed using a validated semi-automated method. WMH and MB were compared according to site of symptomatic hematoma origin (lobar vs. deep) or by pattern of hemorrhages, including both hematomas and MB, on MRI GRE sequence (grouped as lobar only--probable CAA, lobar only--possible CAA, deep hemispheric only, or mixed lobar and deep hemorrhages). Results Lobar and deep hemispheric hematoma patients had similar median nWMH volumes (19.5 cm vs. 19.9 cm3, p=0.74) and prevalence of ≥1 MB (54% vs. 52%, p=0.99). The supratentorial WMH distribution was similar according to hemorrhage location category, however the prevalence of brainstem T2 hyperintensity was lower in lobar hematoma vs. deep hematoma (54% vs. 70%, p=0.004). Mixed ICH was common (23%). Mixed ICH patients had large nWMH volumes and a posterior distribution of cortical hemorrhages similar to that seen in CAA. Conclusions WMH distribution is largely similar between CAA-related and non-CAA-related ICH. Mixed lobar and deep hemorrhages are seen on MRI GRE in up to one quarter of patients; in these patients both hypertension and CAA may be contributing to the burden of WMH. PMID:20689084

MRI markers of small vessel disease in lobar and deep hemispheric intracerebral hemorrhage.

PubMed

Smith, Eric E; Nandigam, Kaveer R N; Chen, Yu-Wei; Jeng, Jed; Salat, David; Halpin, Amy; Frosch, Matthew; Wendell, Lauren; Fazen, Louis; Rosand, Jonathan; Viswanathan, Anand; Greenberg, Steven M

2010-09-01

MRI evidence of small vessel disease is common in intracerebral hemorrhage (ICH). We hypothesized that ICH caused by cerebral amyloid angiopathy (CAA) or hypertensive vasculopathy would have different distributions of MRI T2 white matter hyperintensity (WMH) and microbleeds. Data were analyzed from 133 consecutive patients with primary supratentorial ICH and adequate MRI sequences. CAA was diagnosed using the Boston criteria. WMH segmentation was performed using a validated semiautomated method. WMH and microbleeds were compared according to site of symptomatic hematoma origin (lobar versus deep) or by pattern of hemorrhages, including both hematomas and microbleeds, on MRI gradient recalled echo sequence (grouped as lobar only-probable CAA, lobar only-possible CAA, deep hemispheric only, or mixed lobar and deep hemorrhages). Patients with lobar and deep hemispheric hematoma had similar median normalized WMH volumes (19.5 cm versus 19.9 cm(3), P=0.74) and prevalence of >or=1 microbleed (54% versus 52%, P=0.99). The supratentorial WMH distribution was similar according to hemorrhage location category; however, the prevalence of brain stem T2 hyperintensity was lower in lobar hematoma versus deep hematoma (54% versus 70%, P=0.004). Mixed ICH was common (23%). Patients with mixed ICH had large normalized WMH volumes and a posterior distribution of cortical hemorrhages similar to that seen in CAA. WMH distribution is largely similar between CAA-related and non-CAA-related ICH. Mixed lobar and deep hemorrhages are seen on MRI gradient recalled echo sequence in up to one fourth of patients; in these patients, both hypertension and CAA may be contributing to the burden of WMH.

The Effect of Cold Work on Properties of Alloy 617

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wright, Richard

2014-08-01

Alloy 617 is approved for non-nuclear construction in the ASME Boiler and Pressure Vessel Code Section I and Section VIII, but is not currently qualified for nuclear use in ASME Code Section III. A draft Code Case was submitted in 1992 to qualify the alloy for nuclear service but efforts were stopped before the approval process was completed.1 Renewed interest in high temperature nuclear reactors has resulted in a new effort to qualify Alloy 617 for use in nuclear pressure vessels. The mechanical and physical properties of Alloy 617 were extensively characterized for the VHTR programs in the 1980’s andmore » incorporated into the 1992 draft Code Case. Recently, the properties of modern heats of the alloy that incorporate an additional processing step, electro-slag re-melting, have been characterized both to confirm that the properties of contemporary material are consistent with those in the historical record and to increase the available database. A number of potential issues that were identified as requiring further consideration prior to the withdrawal of the 1992 Code Case are also being re-examined in the current R&D program. Code Cases are again being developed to allow use of Alloy 617 for nuclear design within the rules of the ASME Boiler and Pressure Vessel Code. In general the Code defines two temperature ranges for nuclear design with austenitic and nickel based alloys. Below 427°C (800°F) time dependent behavior is not considered, while above this temperature creep and creep-fatigue are considered to be the dominant life-limiting deformation modes. There is a corresponding differentiation in the treatment of the potential for effects associated with cold work. Below 427°C the principal issue is the relationship between the level of cold work and the propensity for stress corrosion cracking and above that temperature the primary concern is the impact of cold work on creep-rupture behavior.« less

The Hemodynamic Changes in Patients with Cerebral Arteriovenous Malformations before and after Interventional Embolization Therapy with Glubran 2 Acrylic Glue.

PubMed

Chen, Qi-Yu; Zhu, Xiao-Rui; Zhang, Yu

2017-01-01

The study explored hemodynamic changes in patients with cerebral arteriovenous malformations (CAVM) before and -after interventional embolization therapy with Glubran 2 acrylic glue and analyzed the related factors. CAVM patients received endovascular embolization therapy with Glubran 2. Patients' systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP), blood flow velocity (BFV), and pulsatility index (PI) were measured. The location of malformed vessels, Spetzler-Martin (SM) grade, CAVM size, and type of feeding artery and venous drainage were analyzed. CAVM patients showed increased DBP, SBP, MAP, and PI and decreased average BFV compared to before therapy. CAVM patients with big CAVM size, SM grade IV/V, deep location malformed vessels, deep, and mixed venous drainage, and cortical branch and mixed artery blood-supply exhibited lower DBP, SBP, MAP, and PI but higher average BFV. Hypertensive CAVM patients showed lower DBP, SBP, MAP, average BFV, and PI before or after embolization. Hypertension, SM grade, CAVM size, malformed vessels location, venous drainage, and artery blood-supply were correlated to the hemodynamic changes of CAVM patients. Embolization with Glubran 2 acrylic glue could enhance hemodynamics in CAVM patients, and the hemodynamic changes were in correlation with the SM grade, CAVM size, and malformed vessels location. © 2017 S. Karger AG, Basel.

Research Vessel R/V Sikuliaq: Joining the UNOLS Fleet in 2014

NASA Astrophysics Data System (ADS)

Whitledge, T. E.

2013-12-01

The global class research vessel R/V Sikuliaq is being constructed on behalf of the NSF to support future scientific studies in high latitude waters. The 261 foot vessel will be capable of breaking 2.5 foot thick ice at 2 knots with an endurance of 45 days at sea and cruising at 11 knots. The R/V Sikuliaq has a beam of 52 feet and a draft of 18.9 feet that will carry 26 scientists and a crew of 20. Berthing accommodations are a combination of single/double rooms with one stateroom and the common areas of the vessel are designed for ADA access and accommodations. The total laboratory space (main, analytical, electronics, wet, upper, and Baltic room are 2100 square feet. The 4360 square foot working deck that is approximately 70 feet in length will accommodate 2-4 vans and multiple science operations. The vessel design strives to have the lowest possible environmental impact, including a low underwater-radiated noise signature. The science systems are prescribed to be state-of-the-art for bottom mapping, over-the-side 'hands free' gear handling, broad band communications and scientific walk-in freezer and environmental chamber. More details and photos of the construction progress are available on the website at www.sfos.uaf.edu/arrv. The vessel was launched in October 2012 and delivery to the University of Alaska Fairbanks is scheduled for November 2013. Scientific operations following testing and science sea trials are planned to start in summer of 2014. Questions about the science systems or vessel capabilities should be directed to Terry Whitledge (terry@ims.uaf.edu).

R/V SIKULIAQ - A New Ice-capable Asset For The Future UNOLS Fleet

NASA Astrophysics Data System (ADS)

Whitledge, T. E.; Oliver, D. K.

2010-12-01

The University of Alaska Fairbanks is constructing a new research vessel with a contract with Marinette Marine Corp. in Marinette, Wisconsin on behalf of the NSF for future scientific studies with an emphasis in the North Pacific Ocean and Alaskan waters. The 254 foot vessel will be capable of breaking 2.5 foot thick ice at 2 knots with an endurance of 45 days at sea and cruising at 14.2 knots. The vessel has formerly been known as the Alaska Region Research Vessel (ARRV) but has recently been named the R/V Sikuliaq (pronounced [see-KOO-lee-auk] which is an Inupiaq word meaning “new sea ice that is safe to walk on”). The R/V Sikuliaq will have a beam of 52 feet and a draft of 18.9 feet that will carry 26 scientists and a crew of 20. Berthing accommodations are a combination of single/double rooms. One stateroom and the common areas of the vessel are designed for ADA access and accommodations. The total laboratory space (main, analytical, electronics, wet, upper, and Baltic room will be 2100 square feet. The 3690 square foot working deck that is approximately 70 feet in length will accommodate 2-4 vans. The vessel design strives to have the lowest possible environmental impact, including a low underwater-radiated noise signature. The science systems are prescribed to be state-of-the-art for bottom mapping, over-the-side “hands free” gear handling, broad band communications and scientific walk-in freezer and environmental chamber.

Propeller flap reconstruction of abdominal defects: review of the literature and case report.

PubMed

Scaglioni, Mario F; Giuseppe, Alberto Di; Chang, Edward I

2015-01-01

The abdominal wall is perfused anteriorly by the superior and deep epigastric vessels with a smaller contribution from the superficial system. The lateral abdominal wall is perfused predominantly from perforators arising from the intercostal vessels. Reconstruction of soft tissue defects involving the abdomen presents a difficult challenge for reconstructive surgeons. Pedicle perforator propeller flaps can be used to reconstruct defects of the abdomen, and here we present a thorough review of the literature as well as a case illustrating the perforasome propeller flap concept. A patient underwent resection for dermatofibrosarcoma protuberans resulting in a large defect of the epigastric soft tissue. A propeller flap was designed based on a perforator arising from the superior deep epigastric vessels and was rotated 90° into the defect allowing primary closure of the donor site. The patient healed uneventfully and was without recurrent disease 37 months following reconstruction. Perforator propeller flaps can be used successfully in reconstruction of abdominal defects and should be incorporated into the armamentarium of reconstructive microsurgeons already facile with perforator dissections. © 2014 Wiley Periodicals, Inc.

The Hindlimb Arterial Vessels in Lowland paca (Cuniculus paca, Linnaeus 1766).

PubMed

Leal, L M; de Freitas, H M G; Sasahara, T H C; Machado, M R F

2016-04-01

This study aims to describe the origin and distribution of the hindlimb arterial vessels. Five adult lowland pacas (Cuniculus paca) were used. Stained and diluted latex was injected, caudally to the aorta. After fixation in 10% paraformaldehyde for 72 h, we dissected to visualize and identify the vessels. It was found out that the vascularization of the hindlimb in lowland paca derives from the terminal branch of the abdominal aorta. The common iliac artery divides into external iliac and internal iliac. The external iliac artery emits the deep iliac circumflex artery, the pudendal epigastric trunk, the deep femoral artery; the femoral artery originates the saphenous artery, it bifurcates into cranial and caudal saphenous arteries. Immediately after the knee joint, the femoral artery is called popliteal artery, which divides into tibial cranial and tibial caudal arteries at the level of the crural inter-osseous space. The origin and distribution of arteries in the hindlimb of lowland paca resembles that in other wild rodents, as well as in the domestic mammals. © 2014 Blackwell Verlag GmbH.

Energy use in the marine transportation industry. Task II. Efficiency improvements. Draft report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1977-06-02

Research and development areas that hold promise for maritime energy conservation are identified and evaluated. The methodology used in the evaluation of potential research areas and results, conclusions, and recommendations are presented. Fifteen programs are identified in four generic technologies and these are discussed in detail in appendices A-D. The areas are: main propulsion plants, propulsors, hydrodynamics, and vessel operations. Fuels are discussed briefly in appendix E. Additional information is presented on the generic US flag baseline operational and cost parameters; a sample output model is presented. (MCW)

Concept Design Report for a Low draft Stabilized - High Speed Connector (LDS-HSC) Vessel for the ONR High Speed Sea Lift (HSSL) Program

DTIC Science & Technology

2007-04-30

control of cushion air flow and, hence, control of cushion pressure fore and aft of the divider that provides significant dynamic control of ship pitch...fore and aft of the divider that provides significant dynamic control of ship pitch and heave in a seaway. All these modes of operation were tested by...Installed Power, SHP 402,306 Integrated Power System (IPS) featuring: * (6) 50 MW Rolls-Royce MT50 based Gensets Power Plant * Associated Conversion and

15 CFR 971.700 - General.

Code of Federal Regulations, 2010 CFR

2010-01-01

... SERVICE DEEP SEABED MINING REGULATIONS FOR COMMERCIAL RECOVERY PERMITS Safety of Life and Property at Sea... conformity with principles of international law, that vessels documented in the United States and used in...

Aberrant cervical vasculature anastomosis as cause of neck pain and successful treatment with embolization technique.

PubMed

He, Lucy; Ladner, Travis R; Cobb, Mark; Mocco, J

2016-01-27

We report a patient with non-dermatomal radiating neck pain without focal neurologic deficit. Traditional workup could not identify an anatomic or biomechanical cause. Imaging showed a deep cervical vessel centered in the region of pain. Angiography later identified an aberrant anastomosis of this vessel with the occipital artery. Subsequent endovascular embolization of this arterial trunk resulted in complete pain relief. 2016 BMJ Publishing Group Ltd.

Feasibility Study and Environmental Impact Statement, Oakland Inner Harbor, California, Deep-Draft Navigation.

DTIC Science & Technology

1983-06-01

cl~. 0 I ~Ix *~ S I F (V () m C Y wI 0 C. -d concentrations of dissolved oxygen, heavy metals , petrolum hydrocarbons, pesticides, and turbidity...effects at the dredged and disposal sites under consideration. Water quality parameters of concern include: concentrations of dissolved oxygen, heavy ... metals , petroleum hydrocarbons and pesticides. Some groundwater has been pumped from wells penetrating the Meritt Sand. Brackish water of limited use

Deep Sequencing-Identified Kanamycin-Resistant Paenibacillus sp. Strain KS1 Isolated from Epiphyte Tillandsia usneoides (Spanish Moss) in Central Florida, USA

PubMed Central

Govindarajan, Subramaniam S.; Qi, Feng; Li, Jian-Liang; Sahoo, Malaya K.

2017-01-01

ABSTRACT Paenibacillus sp. strain KS1 was isolated from an epiphyte, Tillandsia usneoides (Spanish moss), in central Florida, USA. Here, we report a draft genome sequence of this strain, which consists of a total of 398 contigs spanning 6,508,195 bp, with a G+C content of 46.5% and comprising 5,401 predicted coding sequences. PMID:28153888

Association Between Vessel Density and Visual Acuity in Patients With Diabetic Retinopathy and Poorly Controlled Type 1 Diabetes.

PubMed

Dupas, Bénédicte; Minvielle, Wilfried; Bonnin, Sophie; Couturier, Aude; Erginay, Ali; Massin, Pascale; Gaudric, Alain; Tadayoni, Ramin

2018-05-10

Capillary dropout is a hallmark of diabetic retinopathy, but its role in visual loss remains unclear. To examine how macular vessel density is correlated with visual acuity (VA) in patients younger than 40 years who have type 1 diabetes without macular edema but who have diabetic retinopathy requiring panretinal photocoagulation. Retrospective cohort study of VA and optical coherence tomography angiography data collected from consecutive patients during a single visit to Lariboisière Hospital, a tertiary referral center in Paris, France. The cohort included 22 eyes of 22 patients with type 1 diabetes without macular edema but with bilateral rapidly progressive diabetic retinopathy that was treated with panretinal photocoagulation between August 15, 2015, and December 30, 2016. Eyes were classified into 2 groups by VA: normal (logMAR, 0; Snellen equivalent, 20/20) and decreased (logMAR, >0; Snellen equivalent, <20/20). The control group included 12 eyes from age-matched healthy participants with normal vision. Visual acuity and mean vessel density in 4 retinal vascular plexuses: the superficial vascular plexus and the deep capillary complex, which comprises the intermediate capillary plexus and the deep capillary plexus. Of the 22 participants, 11 (50%) were men, mean (SD) age was 30 (6) years, and mean (SD) hemoglobin A1c level was 8.9% (1.6%). Of the 22 eyes with diabetic retinopathy, 13 (59%) had normal VA and 9 (41%) had decreased VA (mean [SD]: logMAR, 0.12 [0.04]; Snellen equivalent, 20/25). Mean [SE] vessel density was lower for eyes with diabetic retinopathy and normal VA compared with the control group in the superficial vascular plexus (44.1% [0.9%] vs 49.1% [0.9%]; difference, -5.0% [1.3%]; 95% CI, -7.5% to -2.4%; P < .001), in the deep capillary complex (44.3% [1.2%] vs 50.6% [1.3%]; difference, -6.3% [1.8%]; 95% CI, -9.9% to -2.7%; P = .001), in the intermediate capillary plexus (43.8% [1.2%] vs 49.3% [1.2%]; difference, -5.5% [1.7%]; 95% CI, -9.0% to -2.0%; P = .003), and in the deep capillary plexus (24.5% [1.0%] vs 30.5% [1.0%]; difference, -6.1% [1.4%]; 95% CI, -8.9% to -3.2%; P < .001). Mean vessel density was lower in eyes with diabetic retinopathy and decreased VA compared with eyes with diabetic retinopathy and normal VA; the mean (SE) loss was more pronounced in the deep capillary complex (34.6% [1.5%] vs 44.3% [1.2%]; difference, -9.6% [1.9%]; 95% CI, -13.6% to -5.7%; P < .001), especially in the deep capillary plexus (15.2% [1.2%] vs 24.5% [1.0%]; difference, -9.3% [1.5%]; 95% CI, -12.4% to -6.1%; P < .001), than in the superficial vascular plexus (39.6% [1.1%] vs 44.1% [0.9%]; difference, -4.5% [1.4%]; 95% CI, -7.3% to -1.7%; P = .002). These data suggest that in patients with type 1 diabetes without macular edema but with severe nonproliferative or proliferative diabetic retinopathy, decreased VA may be associated with the degree of capillary loss in the deep capillary complex.

THE RELATIONSHIP BETWEEN FOVEAL AVASCULAR ZONE AREA, VESSEL DENSITY, AND CYSTOID CHANGES IN DIABETIC RETINOPATHY, AN OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY STUDY.

PubMed

Tarassoly, Kia; Miraftabi, Arezoo; Soltan Sanjari, Mostafa; Parvaresh, Mohammad Mehdi

2017-06-29

To measure the foveal avascular zone (FAZ) areas and vessel densities of patients with diabetic retinopathy and to study their relationship with diabetic cystoid changes and retinal thickness. Prospective case series of 51 eyes of 31 patients with diabetic retinopathy. The eyes were grouped based on the presence or absence of cystoid edema and evaluated using optical coherence tomography angiography. The FAZ areas and vessel density were compared. The FAZ area at the superficial capillary plexus level was equal between the eyes with and without cystoid edema. Vessel density did not differ as well. There was no correlation with retinal thickness. In eyes with cystoid changes, FAZ area changes at the deep capillary plexus level were difficult to interpret. The FAZ area and vessel density at the superficial capillary plexus level are reproducible and independent of the presence of cystoid edema.

Environmental evaluations for deepening of Richmond Harbor and Santa Fe Channels

DOE Office of Scientific and Technical Information (OSTI.GOV)

Brown, B.; Kohn, N.P.; Crecelius, E.A.

Richland, California is an important commercial port in San Francisco Bay. The San Francisco District of the US Army Corps of Engineers (USACE) plans to increase the depth of Richmond Harbor and Santa Fe Channels to -38 feet Mean Lower Low Water (MLLW) to accommodate deep-draft commercial vessels. The total volume of dredged material is expected to be approximately 1.4 million cubic yards. The options for disposal of the dredged material are aquatic disposal and upland disposal. The purpose of this study was to develop a database on chemical compounds in the dredged material to assist with determination of disposalmore » methods and the need for additional testing. This purpose was accomplished through an extensive field sampling program followed by chemical analysis of samples. Field sampling involved collection of core samples from Sante Fe and Richmond Harbor Channels. Cores were shipped to Battelle/Marine Sciences Laboratory, where they were subsampled for chemical analysis and/or archived by freezing. All sediment and water samples were analyzed for priority pollutants, including metals, organotins, base/neutral semivolatile organic compounds, chlorinated pesticides and PCBs, herbicide acids, and acidic phenols. Sediment samples were also analyzed for oil and grease and total organic carbon. Organophosphorus pesticides and dioxins and furans were measured in selected sediment samples from Richland Harbor Channel and from both sediment and water samples from Santa Fe Channel. 21 refs., 10 figs., 60 tabs.« less

Deep Retinal Layer Microvasculature Dropout detected by the Optical Coherence Tomography Angiography in Glaucoma

PubMed Central

Suh, Min Hee; Zangwill, Linda M.; Manalastas, Patricia Isabel C.; Belghith, Akram; Yarmohammadi, Adeleh; Medeiros, Felipe A.; Diniz-Filho, Alberto; Saunders, Luke J.; Weinreb, Robert N.

2016-01-01

Purpose To investigate factors associated with dropout of the deep retinal layer microvasculature within the β-zone parapapillary atrophy (βPPA) assessed by optical coherence tomography angiography (OCT-A) in glaucomatous eyes. Design Cross-sectional study. Participants Seventy-one eyes from 71 primary open angle glaucoma (POAG) patients with βPPA enrolled in the Diagnostic Innovations in Glaucoma Study. Methods βPPA deep layer microvasculature dropout was defined as a complete loss of the microvasculature located within deep retinal layer of the βPPA from OCT-A-derived optic nerve head vessel density maps by standardized qualitative assessment. Circumpapillary vessel density (cpVD) within the retinal nerve fiber layer (RNFL) was also calculated using OCT-A. Choroidal thickness and presence of the focal lamina cribrosa (LC) defect were determined using swept-source OCT. Main Outcome Measures Presence of the βPPA deep layer microvasculature dropout. Parameters including age, systolic and diastolic blood pressure, axial length, intraocular pressure, disc hemorrhage, cpVD, visual field (VF) mean deviation (MD), focal LC defect, βPPA area, and choroidal thickness were analyzed. Results βPPA deep layer microvasculature dropout was detected in 37 eyes (52.1%) of eyes with POAG. Eyes with dropouts had a higher prevalence of LC defect (70.3 vs. 32.4%), lower cpVD (52.7 vs. 58.8%), worse VF MD (-9.06 vs. -3.83dB), thinner total choroidal thickness (126.5 vs. 169.1/μm), longer axial length (24.7 vs. 24.0mm), larger βPPA (1.2 vs. 0.76mm2) and lower diastolic blood pressure (74.7 vs. 81.7mmHg) than those without dropouts (P< 0.05, respectively). In the multivariate logistic regression, higher prevalence of focal LC defect (odds ratio [OR], 6.27; P = 0.012), reduced cpVD (OR, 1.27; P = 0.002), worse VF MD (OR, 1.27; P = 0.001), thinner choroidal thickness (OR, 1.02; P = 0.014), and lower diastolic blood pressure (OR, 1.16; P = 0.003) were significantly associated with the dropout. Conclusions Certain systemic and ocular factors such as focal LC defect, more advanced disease status, reduced RNFL vessel density, thinner choroidal thickness, and lower diastolic blood pressure were factors associated with the βPPA deep layer microvasculature dropout in glaucomatous eyes. Longitudinal studies are required to elucidate the temporal relationship between βPPA deep layer dropout and these factors. PMID:27769587

Evaluation of macular and peripapillary vessel flow density in eyes with no known pathology using optical coherence tomography angiography.

PubMed

Hassan, Muhammad; Sadiq, Mohammad Ali; Halim, Muhammad Sohail; Afridi, Rubbia; Soliman, Mohamed K; Sarwar, Salman; Agarwal, Aniruddha; Do, Diana V; Nguyen, Quan Dong; Sepah, Yasir Jamal

2017-01-01

To assess normal vessel flow density (VFD) in macular and peripapillary regions of eyes with no known ocular pathology using optical coherence tomography angiography (OCTA). AngioVue (Optovue, Fremont, CA, USA) was used to capture OCTA images. A 3 × 3 mm grid and a 4.5 × 4.5 mm grid was used to scan parafoveal and peripapillary regions, respectively. ReVue software was utilized to measure VFD in five sectors within the inner two circles of ETDRS grid in macular region and correlated to retinal thickness of same sectors. At optic disc, VFD was calculated in six sectors based on Garway-Heath map. Area and morphology of foveal avascular zone (FAZ) was correlated with VFD in central 1 mm. The influence of myopia on mean VFD was also assessed. Twenty-four eyes (mean age: 30 years) were analyzed. Mean VFD in macular sectors was 43.5 (±4.5) and 45.8 (±5.0) % in superficial and deep retinal plexuses, respectively. Mean VFD was significantly higher in deep retinal plexus compared to superficial retinal plexus in all sectors except central 1 mm (p < 0.05). Mean VFD in central 1 mm increases with an increase in central retinal thickness in both superficial and deep retinal plexuses (p < 0.001). Mean parafoveal VFD at level of both superficial and deep retinal plexuses decrease with an increase in spherical equivalent in myopics (p < 0.05). Mean VFD in myopics was found to be significantly lower in parafoveal region of deep retinal plexus (p < 0.05). Mean area of FAZ was 0.33 (±0.15) and 0.47 mm 2 (±0.15) in superficial and deep retinal plexuses, respectively. Area of FAZ decreases with an increase in central 1 mm thickness and foveal VFD (p < 0.001). OCTA may be used to measure VFD in macular and peripapillary regions. Vessels in the parafoveal region are more densely packed in the deep retinal plexus leading to higher VFD compared to superficial plexus. Thicker retina in fovea translates into higher foveal VFD due to more compact arrangement of retinal layers and continuity of inner nuclear layer (INL). Myopia is associated with lower VFD in parafoveal region at level of deep retinal plexuses which may explain thinning of INL in myopics.

Deep Retinal Layer Microvasculature Dropout Detected by the Optical Coherence Tomography Angiography in Glaucoma.

PubMed

Suh, Min Hee; Zangwill, Linda M; Manalastas, Patricia Isabel C; Belghith, Akram; Yarmohammadi, Adeleh; Medeiros, Felipe A; Diniz-Filho, Alberto; Saunders, Luke J; Weinreb, Robert N

2016-12-01

To investigate factors associated with dropout of the parapapillary deep retinal layer microvasculature assessed by optical coherence tomography angiography (OCTA) in glaucomatous eyes. Cross-sectional study. Seventy-one eyes from 71 primary open-angle glaucoma (POAG) patients with β-zone parapapillary atrophy (βPPA) enrolled in the Diagnostic Innovations in Glaucoma Study. Parapapillary deep-layer microvasculature dropout was defined as a complete loss of the microvasculature located within the deep retinal layer of the βPPA from OCTA-derived optic nerve head vessel density maps by standardized qualitative assessment. Circumpapillary vessel density (cpVD) within the retinal nerve fiber layer (RNFL) also was calculated using OCTA. Choroidal thickness and presence of focal lamina cribrosa (LC) defects were determined using swept-source optical coherence tomography. Presence of parapapillary deep-layer microvasculature dropout. Parameters including age, systolic and diastolic blood pressure, axial length, intraocular pressure, disc hemorrhage, cpVD, visual field (VF) mean deviation (MD), focal LC defects βPPA area, and choroidal thickness were analyzed. Parapapillary deep-layer microvasculature dropout was detected in 37 POAG eyes (52.1%). Eyes with microvasculature dropout had a higher prevalence of LC defects (70.3% vs. 32.4%), lower cpVD (52.7% vs. 58.8%), worse VF MD (-9.06 dB vs. -3.83 dB), thinner total choroidal thickness (126.5 μm vs. 169.1 μm), longer axial length (24.7 mm vs. 24.0 mm), larger βPPA (1.2 mm 2 vs. 0.76 mm 2 ), and lower diastolic blood pressure (74.7 mmHg vs. 81.7 mmHg) than those without dropout (P < 0.05, respectively). In the multivariate logistic regression analysis, higher prevalence of focal LC defects (odds ratio [OR], 6.27; P = 0.012), reduced cpVD (OR, 1.27; P = 0.002), worse VF MD (OR, 1.27; P = 0.001), thinner choroidal thickness (OR, 1.02; P = 0.014), and lower diastolic blood pressure (OR, 1.16; P = 0.003) were associated significantly with the dropout. Systemic and ocular factors including focal LC defects more advanced glaucoma, reduced RNFL vessel density, thinner choroidal thickness, and lower diastolic blood pressure were factors associated with the parapapillary deep-layer microvasculature dropout in glaucomatous eyes. Longitudinal studies are required to elucidate the temporal relationship between parapapillary deep-layer microvasculature dropout and systemic and ocular factors. Copyright © 2016 American Academy of Ophthalmology. Published by Elsevier Inc. All rights reserved.

Characterization of an optimized light source and comparison to pulsed dye laser for superficial and deep vessel clearance.

PubMed

Weiss, Robert A; Ross, E Victor; Tanghetti, Emil A; Vasily, David B; Childs, James J; Smirnov, Mikhail Z; Altshuler, Gregory B

2011-02-01

An arc lamp-based device providing optimized spectrum and pulse shape was characterized and compared with two pulsed dye laser (PDL) systems using a vascular phantom. Safety and effectiveness for facial telangiectasia are presented in clinical case studies. An optimized pulsed light source's (OPL) spectral and power output were characterized and compared with two 595 nm PDL devices. Purpuric threshold fluences were determined for the OPL and PDLs on Fitzpatrick type II normal skin. A vascular phantom comprising blood-filled quartz capillaries beneath porcine skin was treated by the devices at their respective purpuric threshold fluences for 3 ms pulse widths, while vessel temperatures were monitored with an infrared (IR) camera. Patients with Fitzpatrick skin types II-III received a split-face treatment with the OPL and a 595 nm PDL. The OPL provided a dual-band output spectrum from 500 to 670 nm and 850-1,200 nm, pulse widths from 3 to 100 ms, and fluences to 80 J/cm(2). The smooth output power measured during all pulse widths provides unambiguous vessel size selectivity. Percent energy in the near infra-red increased with decreasing output power from 45% to 60% and contributed 15-26% to heating of deep vessels, respectively. At purpuric threshold fluences the ratio of OPL to PDL vessel temperature rise was 1.7-2.8. OPL treatments of facial telangiectasia were well-tolerated by patients demonstrating significant improvements comparable to PDL with no downtime. Intense pulsed light (IPL) and PDL output pulse and spectral profiles are important for selective treatment of vessels in vascular lesions. The OPL's margin between purpuric threshold fluence and treatment fluence for deeper, larger vessels was greater than the corresponding margin with PDLs. The results warrant further comparison studies with IPLs and other PDLs. Copyright © 2011 Wiley-Liss, Inc.

High-quality permanent draft genome sequence of the Lebeckia - nodulating Burkholderia dilworthii strain WSM3556T

DOE Office of Scientific and Technical Information (OSTI.GOV)

De Meyer, Sofie E.; Tian, Rui; Seshadri, Rekha

Burkholderia dilworthii strain WSM3556T is an aerobic, motile, Gram-negative, non-spore-forming rod that was isolated from an effective N2-fixing root nodule of Lebeckia ambigua collected near Grotto Bay Nature Reserve, in the Western Cape of South Africa, in October 2004. This plant persists in infertile and deep sandy soils with acidic pH, and is therefore an ideal candidate for a perennial based agriculture system in Western Australia. WSM3556T thus represents a potential inoculant quality strain for L. ambigua for which we describe the general features, together with genome sequence and annotation. Lastly, the 7,679,067 bp high-quality permanent draft genome is arrangedmore » in 140 scaffolds of 141 contigs, contains 7,059 protein-coding genes and 64 RNA-only encoding genes, and is part of the GEBA-RNB project proposal.« less

High-quality permanent draft genome sequence of the Lebeckia ambigua-nodulating Burkholderia sp. strain WSM4176

DOE Office of Scientific and Technical Information (OSTI.GOV)

De Meyer, Sofie E.; Tian, Rui; Seshadri, Rekha

We report that Burkholderia sp. strain WSM4176 is an aerobic, motile, Gram-negative, non-spore-forming rod that was isolated from an effective N2-fixing root nodule of Lebeckia ambigua collected in Nieuwoudtville, Western Cape of South Africa, in October 2007. This plant persists in infertile, acidic and deep sandy soils, and is therefore an ideal candidate for a perennial based agriculture system in Western Australia. Here we describe the features of Burkholderia sp. strain WSM4176, which represents a potential inoculant quality strain for L. ambigua, together with sequence and annotation. The 9,065,247 bp high-quality-draft genome is arranged in 13 scaffolds of 65 contigs,more » contains 8369 protein-coding genes and 128 RNA-only encoding genes, and is part of the GEBA-RNB project proposal (Project ID 882).« less

High-quality permanent draft genome sequence of the Lebeckia - nodulating Burkholderia dilworthii strain WSM3556T

DOE PAGES

De Meyer, Sofie E.; Tian, Rui; Seshadri, Rekha; ...

2015-09-19

Burkholderia dilworthii strain WSM3556T is an aerobic, motile, Gram-negative, non-spore-forming rod that was isolated from an effective N2-fixing root nodule of Lebeckia ambigua collected near Grotto Bay Nature Reserve, in the Western Cape of South Africa, in October 2004. This plant persists in infertile and deep sandy soils with acidic pH, and is therefore an ideal candidate for a perennial based agriculture system in Western Australia. WSM3556T thus represents a potential inoculant quality strain for L. ambigua for which we describe the general features, together with genome sequence and annotation. Lastly, the 7,679,067 bp high-quality permanent draft genome is arrangedmore » in 140 scaffolds of 141 contigs, contains 7,059 protein-coding genes and 64 RNA-only encoding genes, and is part of the GEBA-RNB project proposal.« less

High-quality permanent draft genome sequence of the Lebeckia ambigua-nodulating Burkholderia sp. strain WSM4176

DOE PAGES

De Meyer, Sofie E.; Tian, Rui; Seshadri, Rekha; ...

2015-10-16

We report that Burkholderia sp. strain WSM4176 is an aerobic, motile, Gram-negative, non-spore-forming rod that was isolated from an effective N2-fixing root nodule of Lebeckia ambigua collected in Nieuwoudtville, Western Cape of South Africa, in October 2007. This plant persists in infertile, acidic and deep sandy soils, and is therefore an ideal candidate for a perennial based agriculture system in Western Australia. Here we describe the features of Burkholderia sp. strain WSM4176, which represents a potential inoculant quality strain for L. ambigua, together with sequence and annotation. The 9,065,247 bp high-quality-draft genome is arranged in 13 scaffolds of 65 contigs,more » contains 8369 protein-coding genes and 128 RNA-only encoding genes, and is part of the GEBA-RNB project proposal (Project ID 882).« less

Research Vessel R/V Sikuliaq: A New Asset For The UNOLS Fleet

NASA Astrophysics Data System (ADS)

Whitledge, T. E.

2012-12-01

The research vessel R/V Sikuliaq is currently being constructed on behalf of the NSF to support future scientific studies in high latitude waters. The 261 foot global class vessel will be capable of breaking 2.5 foot thick ice at 2 knots with an endurance of 45 days at sea and cruising at 11 knots. The R/V Sikuliaq will have a beam of 52 feet and a draft of 18.9 feet that will carry 26 scientists and a crew of 20. Berthing accommodations are a combination of single/double rooms with one stateroom and the common areas of the vessel are designed for ADA access and accommodations. The total laboratory space (main, analytical, electronics, wet, upper, and Baltic room will be 2100 square feet. The 4360 square foot working deck that is approximately 70 feet in length will accommodate 2-4 vans and multiple science operations. The vessel design strives to have the lowest possible environmental impact, including a low underwater-radiated noise signature. The science systems are prescribed to be state-of-the-art for bottom mapping, over-the-side "hands free" gear handling, broad band communications and scientific walk-in freezer and environmental chamber. More details and photos of the construction progress are available on the website at www.sfos.uaf.edu/arrv. The shipyard schedule has a launch date of October 2012 and delivery to the University of Alaska Fairbanks in July 2013. Scientific operations following trials and testing is planned to start in January 2014. Questions about the science systems or vessel capabilities should be directed to Terry Whitledge (terry@ims.uaf.edu).;

How to evaluate the microcirculation: report of a round table conference

PubMed Central

De Backer, Daniel; Hollenberg, Steven; Boerma, Christiaan; Goedhart, Peter; Büchele, Gustavo; Ospina-Tascon, Gustavo; Dobbe, Iwan; Ince, Can

2007-01-01

Introduction Microvascular alterations may play an important role in the development of organ failure in critically ill patients and especially in sepsis. Recent advances in technology have allowed visualization of the microcirculation, but several scoring systems have been used so it is sometimes difficult to compare studies. This paper reports the results of a round table conference that was organized in Amsterdam in November 2006 in order to achieve consensus on image acquisition and analysis. Methods The participants convened to discuss the various aspects of image acquisition and the different scores, and a consensus statement was drafted using the Delphi methodology. Results The participants identified the following five key points for optimal image acquisition: five sites per organ, avoidance of pressure artifacts, elimination of secretions, adequate focus and contrast adjustment, and recording quality. The scores that can be used to describe numerically the microcirculatory images consist of the following: a measure of vessel density (total and perfused vessel density; two indices of perfusion of the vessels (proportion of perfused vessels and microcirculatory flow index); and a heterogeneity index. In addition, this information should be provided for all vessels and for small vessels (mostly capillaries) identified as smaller than 20 μm. Venular perfusion should be reported as a quality control index, because venules should always be perfused in the absence of pressure artifact. It is anticipated that although this information is currently obtained manually, it is likely that image analysis software will ease analysis in the future. Conclusion We proposed that scoring of the microcirculation should include an index of vascular density, assessment of capillary perfusion and a heterogeneity index. PMID:17845716

Different Recipient Vessels for Free Microsurgical Fibula Flaps in the Treatment of Avascular Necrosis of the Femoral Head: A Systematic Review and Meta-analysis.

PubMed

Tu, Yiji; Chen, Zenggan; Lineaweaver, William Charles; Zhang, Feng

2017-12-01

Several recipient vessels can be used in free microsurgical fibula flaps (MFFs) for the treatment of avascular necrosis of the femoral head (ANFH). Few articles investigate the influence of different recipient vessels on outcomes of MFF for ANFH. A comprehensive literature search of databases including PubMed-Medline, Ovid-Embase, and Cochrane Library was performed to collect the related studies. The Medical Subject Headings used were "femur head necrosis" and "bone transplantation." The relevant words in title or abstract included but not limited to "fibula flap," "fibular flap," "vascularized fibula," "vascularized fibular," "free fibula," "free fibular," "femoral head necrosis," "avascular necrosis of femoral head," and "ischemic necrosis of femoral head." The methodological index for nonrandomized studies was adopted for assessing the studies included in this review. Finally, 15 studies encompassing a total of 1267 patients (1603 hips) with ANFH were pooled in the overall analysis. Recipient vessels for MFF included the ascending branch of the lateral circumflex femoral artery and vein in 8 studies, descending branch of the lateral circumflex femoral artery and vein in 2 studies, second perforating branch of the deep femoral artery and vein in 4 studies, and inferior gluteal artery and vein in 1 study. Preoperative and postoperative average Harris hip score and pooled analyses of the rate of conversion, radiographic progression, and hip surgery-related complications showed no significant difference on the outcomes of MFF on ANFH between using different recipient vessels. Different recipient vessels did not affect outcomes in MFF procedures for ANFH. High-quality randomized controlled trials and prospective studies would be necessary to clarify reliable advantages and disadvantages between different recipient vessels. Until then, surgeons are justified in using ascending branch of the lateral circumflex femoral artery and vein, descending branch of the lateral circumflex femoral artery and vein, second perforating branch of the deep femoral artery and vein, and inferior gluteal artery and vein vessels according to care circumstances and customary practice.

Summer 1983 Leeway Drift Experiment.

DTIC Science & Technology

1985-08-01

used as the basis for the SAR Manual’s recommendation ( Scobie and Thompson, 1979). The RFD raft was deflected to the right or left of the wind...a leeway study for undrogued, canopied life rafts ( Scobie and Thompson, 1979). The current was measured by a buoy equipped with a 10-foot (3 m...recommendation for the canopied rafts with deep-draft ballast systems is based on data using a buoy with a 10-foot (3-m) square window-shade drogue ( Scobie

Deep Sequencing-Identified Kanamycin-Resistant Paenibacillus sp. Strain KS1 Isolated from Epiphyte Tillandsia usneoides (Spanish Moss) in Central Florida, USA.

PubMed

Lata, Pushpa; Govindarajan, Subramaniam S; Qi, Feng; Li, Jian-Liang; Sahoo, Malaya K

2017-02-02

Paenibacillus sp. strain KS1 was isolated from an epiphyte, Tillandsia usneoides (Spanish moss), in central Florida, USA. Here, we report a draft genome sequence of this strain, which consists of a total of 398 contigs spanning 6,508,195 bp, with a G+C content of 46.5% and comprising 5,401 predicted coding sequences. Copyright © 2017 Lata et al.

[Treatment of adult avascular necrosis of femoral head by transplanting iliac bone flap with deep iliac circumflex vessels and cancellous bone].

PubMed

Yu, Zhiliang; Zhang, Ning; Yang, Yi; Wang, Bin; Gao, Shuo; Zhao, Xiaoyong

2013-07-01

To investigate the effectiveness of transplanting iliac bone flap with deep iliac circumflex vessels and cancellous bone for the treatment of adult avascular necrosis of the femoral head (ANFH). A retrospective analysis was made on the clinical data of 685 patients (803 hips) with ANFH, who underwent iliac bone flap transplantation with deep iliac circumflex vessels and cancellous bone between March 2002 and January 2010. There were 489 males (580 hips) and 196 females (223 hips) with a mean age of 40.4 years (range, 18-63 years), including 567 unilateral cases (303 left hips and 264 right hips) and 118 bilateral cases. The causes of ANFH included alcohol-induced in 223 cases, steroid-induced in 179 cases, alcohol + steroid-induced in 21 cases, traumatic in 136 cases, acetabular dysplasia in 8 cases, bone cyst in 5 cases, septic arthritis in 2 cases, joint tuberculosis in 3 cases, rheumatoid arthritis in 5 cases, and idiopathic in 103 cases. According to Steinberg staging, 211 hips were rated as stage II, 513 hips as stage III, and 79 hips as stage IV. The preoperative Harris hip score was 60.30 +/- 7.02. Fat necrosis occurred in 2 cases after operation, primary healing of incision was obtained in the other cases; delayed infection, lower extremity deep vein thrombosis, and pulmonary embolism occurred in 2 cases, respectively. All patients were followed up 36-60 months (mean, 49 months). Harris hip score at last follow-up (83.50 +/- 7.31) was significantly higher than that at preoperation (t= -2 266.980, P=0.000), and the scores were significantly higher than those at preoperation in different stages (P < 0.05). The results were excellent in 523 hips, good in 185 hips, fair in 65 hips, and poor in 30 hips, and the excellent and good rate was 88.2%. X-ray examination showed bone fusion of transplanted bone flap and bone graft with an average of 4.2 months (range, 3-6 months); according to Steinberg staging, imaging stable rate was 78.3% (629/803) at last follow-up. Iliac bone flap transplantion with deep iliac circumflex vessels and cancellous bone has the advantages of complete decompression of the femoral head, exact flap blood supply, improved blood supply of the femoral head, new support for the femoral head, and participation of osteoinductive effect for the treatment of adult ANFH, so it is an effective treatment for the retention of the femoral head.

Development and applications of an acoustic package for deep-sea sub-bottom profiling and detailed seafloor imaging

NASA Astrophysics Data System (ADS)

Nishimura, Kiyokazu; Kisimoto, Kiyoyuki; Joshima, Masato; Arai, Kohsaku

In the deep-sea geological survey, good survey results are difficult to obtain by a conventional surface-towed acoustic survey system, because the horizontal resolution is limited due to the long distance between the sensor and the target (seafloor). In order to improve the horizontal resolution, a deep-tow system, which tows the sensor in the vicinity of seafloor, is most practical, and many such systems have been developed and used until today. It is not easy, however, to carry out a high-density survey in a small area by maneuvering the towing body altitude sufficiently close to the seafloor with rugged topography. A ROV (Remotely Operated Vehicle) can be used to solve this problem. The ROV makes a high-density 2D survey feasible because of its maneuverability, although a long-distance survey is difficult with it. Accordingly, we have developed an acoustic survey system installed on a ROV. The system named DAIPACK (Deep-sea Acoustic Imaging Package) consists of (1) a deep-sea sub-bottom profiler and (2) a deep-sea sidescan sonar. (1) Deep-sea sub-bottom profiler A light-weight and compact sub-bottom profiler for shallow water was chosen to improve and repackage for the deep sea usage. The system is composed of three units; a transducer, an electronic unit and a notebook computer for system control and data acquisition. The source frequency is 10kHz. To convert the system for the deep sea, the transducer was exchanged for the deep sea model, and the electronic unit was improved accordingly. The electronic unit and the notebook computer were installed in a spherical pressure vessel. (2) Deep-sea sidescan sonar We remodeled a compact shallow sea sidescan sonar(water depth limitation is 30m ) into a deep sea one. This sidescan sonar is composed of a sonar towfish (transducers and an electronic unit ), a cable and a notebook computer (data processor). To accommodate in the deep water, the transducers were remodeled into a high pressure resistance type, and the electronic unit and the computer unit were stored in a spherical pressure vessel. The frequency output of the sidescan sonar is 330kHz, and the ranging distance is variable from 15m to 120m (one side).

[Small vessel cerebrovascular disease].

PubMed

Cardona Portela, P; Escrig Avellaneda, A

2018-05-09

Small vessel vascular disease is a spectrum of different conditions that includes lacunar infarction, alteration of deep white matter, or microbleeds. Hypertension is the main risk factor, although the atherothrombotic lesion may be present, particularly in large-sized lacunar infarctions along with other vascular risk factors. MRI findings are characteristic and the lesions authentic biomarkers that allow differentiating the value of risk factors and defining their prognostic value. Copyright © 2018 SEH-LELHA. Publicado por Elsevier España, S.L.U. All rights reserved.

Preliminary Computational Fluid Dynamics (CFD) Simulation of EIIB Push Barge in Shallow Water

NASA Astrophysics Data System (ADS)

Beneš, Petr; Kollárik, Róbert

2011-12-01

This study presents preliminary CFD simulation of EIIb push barge in inland conditions using CFD software Ansys Fluent. The RANSE (Reynolds Averaged Navier-Stokes Equation) methods are used for the viscosity solution of turbulent flow around the ship hull. Different RANSE methods are used for the comparison of their results in ship resistance calculations, for selecting the appropriate and removing inappropriate methods. This study further familiarizes on the creation of geometrical model which considers exact water depth to vessel draft ratio in shallow water conditions, grid generation, setting mathematical model in Fluent and evaluation of the simulations results.

Real-Time Color-Doppler Guidance of HIFU for the Selective Avoidance or Occlusion of Blood Vessels

NASA Astrophysics Data System (ADS)

Rabkin, Brian A.; Zderic, Vesna; Vaezy, Shahram

2005-03-01

High-intensity focused ultrasound (HIFU) has been shown to effectively occlude blood vessels deep within tissue. The objective of the current study was to synchronize HIFU and color-Doppler ultrasound (US) for the real-time visualization of flow within blood vessels during HIFU treatment. The excitation of the HIFU was synchronized with the color-Doppler imager by collecting the excitation pulses of one of the elements of either a curved array intracavitary (C 9-5) or an intraoperative (CL 10-5) imaging probe. The collected excitation pulse was converted into a TTL-high pulse, which was delayed and gated to time the excitation duration and location of the HIFU pulse with respect to each imaging frame. The single pulse was used to drive a 3.2 MHz concave HIFU transducer (focal length of 3.5 cm, f-number 1) while the US imager was not collecting RF signals from the treatment region of the US image. The feasibility of the system was demonstrated in vivo by the selective ablation of tissue adjacent to, or the occlusion of, large vessels (including the femoral artery) both transcutaneously and interoperatively in the rabbit and pig. For the occlusion of vessels, the HIFU focus was placed immediately distal (with respect to the transducer) to the vessel at a depth of 2-2.5 cm. HIFU was applied at in situ intensities of 1000-2000 W/cm2, at a duty cycle of 50-75%, and a HIFU pulse repetition frequency (set by the US image frame rate) of 6-18 Hz. During each HIFU exposure, the HIFU pulse resulted in color interference bands running vertically within the color-Doppler window. Through the synchronization of the US imager with the HIFU excitation, the location and duration of the interference bands were set outside the treatment region within each image frame. This provided the operator with a clear view of the HIFU treatment site during therapy. Gross assessment showed necrosis of the tissue surrounding the HIFU treated vessel and occlusion of vessels up to 4 mm in diameter after a 30 s HIFU exposure. We have developed a method of synchronizing pulsed HIFU with color-Doppler US imaging for the real-time visualization of flow within blood vessels during HIFU therapy. This provides a means of guiding HIFU therapy for the detection and occlusion of deep vessels, or the selective ablation of tissue surrounding the vessels without vascular occlusion.

Dredging with the Blake

NASA Astrophysics Data System (ADS)

In the early part of the 19th century it was commonly thought that marine life existed only in the upper levels of the oceans. In later years, animals were recovered from successively greater depths, so that by the time of the Challenger expedition in 1873, life seemed to exist almost everywhere in the ocean and on the sea floor. The remarkable abundance of the deep sea fascinated naturalists world-wide, and in 1877 the U.S. Coast Survey steamer Blake was outfitted for deep dredging and trawling, to be done in conjunction with sounding surveys of the eastern U.S. continental shelf and slope. With a waterline length of only 140 feet (43 m), the Blake was a rather small vessel for such arduous service, but these limitations were more than compensated for by Alexander Agassiz, who directed the first dredging survey, and Lieutenant Sigsbee, who commanded the vessel.

Intravascular detection of Giardia trophozoites in naturally infected mice. An electron microscopic study.

PubMed

el-Shewy, K A; Eid, R A

2003-06-01

During routine transmission electron microscopic (TEM) examination of mice naturally infected with Giardia muris, an intense infection with Giardia trophozoites was demonstrated within intestinal and renal tissues. Examination of randomly taken sections from these heavily infected tissues revealed marked deep affection with mixed pathology. Duodenal sections were found loaded with Giardia trophozoites in intimate contact with necrotic gut cells. Some of these trophozoites were detected within central lacteal of damaged villi and nearby blood vessels. Interestingly, and for the first time to be demonstrated, morphologically identical G. muris trophozoite was detected in a renal blood vessel. An intense cellular immune reaction was obviously demonstrated with remarkable interaction between giant macrophages and the trophozoites particulates. Involvement of deep tissues by Giardia trophozoites and their presence within vascular channels could open up questions about the possible invasive and disseminative behavior of G. muris, particularly in heavily and naturally infected hosts.

Drilling Polar Oceans with the European Research Icebreaker AURORA BOREALIS: the IODP Context

NASA Astrophysics Data System (ADS)

Lembke-Jene, Lester; Wolff-Boenisch, Bonnie; Azzolini, Roberto; Thiede, Joern; Biebow, Nicole; Eldholm, Olav; Egerton, Paul

2010-05-01

Polar oceans are characterized by extreme environmental conditions for humans and materials, and have remained the least accessible regions to scientists of the IODP. DSDP and ODP have for long faced specific technical and logistical problems when attempting to drill in ice-covered polar deep-sea basins. The Arctic Ocean and large areas of the high-latitude Southern Ocean remained largely un-sampled by ODP and remain one of the major scientific and technological challenges for IODP. Drilling in these regions has been discussed and anticipated for decades and the scientific rationales are reflected in the science plans of the international Nansen Arctic Drilling Program (NAD) or the Arctic Program Planning Group (APPG) of ODP/IODP, amongst others. More recently, the rationale to investigate the polar oceans in a holistic approach has been outlined by workshops, leading to strategic assessments of the scientific potential and new drilling proposals. The European Polar Board took the initiative to develop a plan for a novel and dedicated research icebreaker with technical capabilities hitherto unrealised. This research icebreaker will enable autonomous operations in the central Arctic Ocean and the Southern Ocean, even during the severest ice conditions in the deep winter, serving all marine disciplines of polar research including scientific drilling: The European Research Icebreaker and Deep-Sea Drilling Vessel AURORA BOREALIS. AURORA BOREALIS is presently planned as a multi-purpose vessel. The ship can be deployed as a research icebreaker in all polar waters during any season of the year, as it shall meet the specifications of the highest ice-class attainable (IACS Polar Code 1) for icebreakers. During the times when it is not employed for drilling, it will operate as the most technically advanced multi-disciplinary research vessel in the Arctic or polar Southern Ocean. AURORA BOREALIS will be a "European scientific flagship facility" (fully open to non-European partners), a multidisciplinary platform for studies ranging from the sub-seafloor into the atmosphere. AURORA BOREALIS was planned for her role in deep-sea drilling in consultation with engineers and technical experts familiar with the program and the operation of these vessels. All techniques currently deployed on IODP expeditions can be implemented onboard the vessel under polar weather and ice conditions, including the full range of re-entry, casing and cementing, and instrumentation options and the entire suite of downhole logging tools. Due to sufficient laboratory space, a full analytical workflow can be easily established comparable to existing permanent platforms, including clean rooms, diverse scanning and logging or incubation facilities. While the vessel is equipped with a dedicated deep-sea drilling rig, other coring and drilling techniques can be employed if needed (e.g. Rockdrill, MEBO, large diameter Kasten cores). AURORA BOREALIS is fitted to operate a CALYPSO Piston Coring System in polar waters. Future mud-return systems under consideration and testing for IODP to provide controlled borehole conditions in difficult facies are compatible with the layout of AURORA BOREALIS. The berthing capacity of 120 personnel total (scientists, technical support and crew) allows to accommodate a sufficient number of science party members offshore. The present scientific implementation documents plan for about one polar scientific drilling expedition per year in a to-be-determined configuration. As the vessel is a multi-dsiciplinary platform, operations for the entire year are not dependant on drilling operations alone. While principal access to the vessel will be based on a competitive proposal review and evaluation system, the allocation of timeslots specifically for drilling would preferably be given over to IODP handling and planning systems in a cooperative mode using the strengths and capacitites of the future program. Depending on interests and needs of the scientific communities a preferential focus in non-drilling expedition planning could be established e.g. for dedicated geophysical pre-site survey works in areas inaccessible by other vessels to secure critical data needed for later drilling expeditions. Based on ongoing expert consultations, it is safe to assume that the average costs for an Arctic or polar drilling expedition will be considerably lower than with an otherwise necessary multi-ship setup based on modelled expedition scenarios and annual operational cost calculations. Still, AURORA BOREALIS shall provide substantially enhanced scientific, operational, personnel and technical capacities offshore.

77 FR 41332 - Fisheries of the Exclusive Economic Zone Off Alaska; Arrowtooth Flounder, Flathead Sole, Rex Sole...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-13

...NMFS is prohibiting directed fishing for arrowtooth flounder, flathead sole, rex sole, deep-water flatfish, and shallow-water flatfish in the Western Regulatory Area of the Gulf of Alaska (GOA). This action is necessary to limit incidental catch of Pacific ocean perch by vessels fishing for arrowtooth flounder, flathead sole, rex sole, deep-water flatfish, and shallow-water flatfish in the Western Regulatory Area of the GOA.

Delivering culturally sensitive health messages: the process of adapting brochures for grandparents raising grandchildren in Hawai'i.

PubMed

Yancura, Loriena A

2010-05-01

The efficacy of programs to reduce health disparities depends on their ability to deliver messages in a culturally sensitive manner. This article describes the process of designing a series of brochures for grandparents raising grandchildren. National source material on topics important to grandparents (self-care, service use, addiction, and grandchildren's difficult behaviors) was put into draft brochures and pilot tested in two focus groups drawn from Native Hawaiian Asian and Pacific Islander populations. Elements of surface and deep levels directed the form and content of the final brochures. On a surface level, these brochures reflect local culture through pictures and language. On a deep level, which integrates cultural beliefs and practices, they reflect the importance of indirect communication and harmonious relationships. The final brochures have been received favorably in the community. The process of adapting educational material with attention to surface and deep levels can serve as a guide for other health promotion materials.

Deep Bleeder Acoustic Coagulation (DBAC)-part II: in vivo testing of a research prototype system.

PubMed

Sekins, K Michael; Barnes, Stephen R; Fan, Liexiang; Hopple, Jerry D; Hsu, Stephen J; Kook, John; Lee, Chi-Yin; Maleke, Caroline; Zeng, Xiaozheng Jenny; Moreau-Gobard, Romain; Ahiekpor-Dravi, Alexis; Funka-Lea, Gareth; Eaton, John; Wong, Keith; Keneman, Scott; Mitchell, Stuart B; Dunmire, Barbrina; Kucewicz, John C; Clubb, Fred J; Miller, Matthew W; Crum, Lawrence A

2015-01-01

Deep Bleeder Acoustic Coagulation (DBAC) is an ultrasound image-guided high-intensity focused ultrasound (HIFU) method proposed to automatically detect and localize (D&L) and treat deep, bleeding, combat wounds in the limbs of soldiers. A prototype DBAC system consisting of an applicator and control unit was developed for testing on animals. To enhance control, and thus safety, of the ultimate human DBAC autonomous product system, a thermal coagulation strategy that minimized cavitation, boiling, and non-linear behaviors was used. The in vivo DBAC applicator design had four therapy tiles (Tx) and two 3D (volume) imaging probes (Ix) and was configured to be compatible with a porcine limb bleeder model developed in this research. The DBAC applicator was evaluated under quantitative test conditions (e.g., bleeder depths, flow rates, treatment time limits, and dose exposure time limits) in an in vivo study (final exam) comprising 12 bleeder treatments in three swine. To quantify blood flow rates, the "bleeder" targets were intact arterial branches, i.e., the superficial femoral artery (SFA) and a deep femoral artery (DFA). D&L identified, characterized, and targeted bleeders. The therapy sequence selected Tx arrays and determined the acoustic power and Tx beam steering, focus, and scan patterns. The user interface commands consisted of two buttons: "Start D&L" and "Start Therapy." Targeting accuracy was assessed by necropsy and histologic exams and efficacy (vessel coagulative occlusion) by angiography and histology. The D&L process (Part I article, J Ther Ultrasound, 2015 (this issue)) executed fully in all cases in under 5 min and targeting evaluation showed 11 of 12 thermal lesions centered on the correct vessel subsection, with minimal damage to adjacent structures. The automated therapy sequence also executed properly, with select manual steps. Because the dose exposure time limit (t dose ≤ 30 s) was associated with nonefficacious treatment, 60-s dosing and dual-dosing was also pursued. Thrombogenic evidence (blood clotting) and collagen denaturation (vessel shrinkage) were found in necropsy and histologically in all targeted SFAs. Acute SFA reductions in blood flow (20-30 %) were achieved in one subject, and one partial and one complete vessel occlusion were confirmed angiographically. The complete occlusion case was achieved with a dual dose (90 s total exposure) with focal intensity ≈500 W/cm(2) (spatial average, temporal average). While not meeting all in vivo objectives, the overall performance of the DBAC applicator was positive. In particular, D&L automation workflow was verified during each of the tests, with processing times well under specified (10 min) limits, and all bleeder branches were detected and localized. Further, gross necropsy and tissue examination confirmed that the HIFU thermal lesions were coincident with the target vessel locations in over 90 % of the multi-array dosing treatments. The SFA/DFA bleeder models selected, and the protocols used, were the most suitable practical model options for the given DBAC anatomical and bleeder requirements. The animal models were imperfect in some challenging aspects, including requiring tissue-mimicking material (TMM) standoffs to achieve deep target depths, thereby introducing device-tissue motion, with resultant imaging artifacts. The model "bleeders" involved intact vessels, which are subject to less efficient heating and coagulation cascade behaviors than true puncture injuries.

Retinal blood vessel segmentation using fully convolutional network with transfer learning.

PubMed

Jiang, Zhexin; Zhang, Hao; Wang, Yi; Ko, Seok-Bum

2018-04-26

Since the retinal blood vessel has been acknowledged as an indispensable element in both ophthalmological and cardiovascular disease diagnosis, the accurate segmentation of the retinal vessel tree has become the prerequisite step for automated or computer-aided diagnosis systems. In this paper, a supervised method is presented based on a pre-trained fully convolutional network through transfer learning. This proposed method has simplified the typical retinal vessel segmentation problem from full-size image segmentation to regional vessel element recognition and result merging. Meanwhile, additional unsupervised image post-processing techniques are applied to this proposed method so as to refine the final result. Extensive experiments have been conducted on DRIVE, STARE, CHASE_DB1 and HRF databases, and the accuracy of the cross-database test on these four databases is state-of-the-art, which also presents the high robustness of the proposed approach. This successful result has not only contributed to the area of automated retinal blood vessel segmentation but also supports the effectiveness of transfer learning when applying deep learning technique to medical imaging. Copyright © 2018 Elsevier Ltd. All rights reserved.

Hybrid Tank Technology

NASA Technical Reports Server (NTRS)

2004-01-01

Researchers have accomplished great advances in pressure vessel technology by applying high-performance composite materials as an over-wrap to metal-lined pressure vessels. These composite over-wrapped pressure vessels (COPVs) are used in many areas, from air tanks for firefighters and compressed natural gas tanks for automobiles, to pressurant tanks for aerospace launch vehicles and propellant tanks for satellites and deep-space exploration vehicles. NASA and commercial industry are continually striving to find new ways to make high-performance pressure vessels safer and more reliable. While COPVs are much lighter than all-metal pressure vessels, the composite material, typically graphite fibers with an epoxy matrix resin, is vulnerable to impact damage. Carbon fiber is most frequently used for the high-performance COPV applications because of its high strength-to-weight characteristics. Other fibers have been used, but with limitations. For example, fiberglass is inexpensive but much heavier than carbon. Aramid fibers are impact resistant but have less strength than carbon and their performance tends to deteriorate.

Spectral-Domain Optical Coherence Tomographic Angiography in Children With Amblyopia.

PubMed

Lonngi, Marcela; Velez, Federico G; Tsui, Irena; Davila, Juan Pablo; Rahimi, Mansour; Chan, Clarissa; Sarraf, David; Demer, Joseph L; Pineles, Stacy L

2017-10-01

Amblyopia is the most common cause of visual impairment in childhood, with a prevalence of 1% to 4% in children in the United States. To date, no studies using noninvasive optical coherence tomographic angiography (OCTA) have measured blood flow in the retinal capillary layers in children with amblyopia. To evaluate the retinal and microvascular features using OCTA in children (<18 years) with amblyopia. This observational case-control study enrolled patients from September 1, 2016, through May 31, 2017, and was conducted from September 1, 2016, through June 30, 2017, at the Stein Eye Institute at UCLA (University of California, Los Angeles). Participants included 59 children (<18 years) with amblyopia and without amblyopia examined at a pediatric ophthalmology clinic or referred to the clinic by coinvestigators. All patients underwent comprehensive ophthalmological examination, including visual acuity, refraction, and ocular motility tests; anterior and posterior segment examination; and OCTA. Reduced superficial and deep retinal capillary vessel density on OCTA. Of the 63 eyes evaluated, 13 (21%) were amblyopic and 50 (79%) were control eyes. Of the 59 patients, the mean (SD) age of patients with amblyopia was 8.0 (4.0) years and 10.3 (3.3) years for the controls; 33 patients (56%) were female; and 5 of 13 (39%) and 27 of 46 (54%) patients in the amblyopic and control groups, respectively, were identified as white. The macular vessel density of the superficial capillary plexus was lower in the amblyopic group than in the control group in both 3 × 3-mm and 6 × 6-mm scans. After adjusting for age and refractive error, the mean (SD) difference in the superficial capillary plexus in the 6 × 6-mm scan was statistically significant (49.3% [4.1] vs 51.2% [2.9]; P = .02). Macular vessel density of the deep capillary plexus in the 6 × 6-mm scans was also considerably different between groups: mean (SD) vessel density of the deep retinal capillary plexus was 54.4% (4.7%) in the amblyopia group and 60.1% (3.3%) in the control group, with a difference of 5.7% (95% CI, 3.4%-8.1%; P = .002). The study found that OCTA reveals subnormal superficial and deep retinal capillary density in the macula of patients with amblyopia. Further studies are needed to determine the clinical relevance of this finding.

Distribution of sensory nerve endings around the human sinus tarsi: a cadaver study

PubMed Central

Rein, Susanne; Manthey, Suzanne; Zwipp, Hans; Witt, Andreas

2014-01-01

The aim of this study was to analyse the pattern of sensory nerve endings and blood vessels around the sinus tarsi. The superficial and deep parts of the fat pads at the inferior extensor retinaculum (IER) as well as the subtalar joint capsule inside the sinus tarsi from 13 cadaver feet were dissected. The distribution of the sensory nerve endings and blood vessels were analysed in the resected specimens as the number per cm2 after staining with haematoxylin-eosin, S100 protein, low-affinity neurotrophin receptor p75, and protein gene product 9.5 using the classification of Freeman and Wyke. Free nerve endings were the predominant sensory ending (P < 0.001). Ruffini and Golgi-like endings were rarely found and no Pacini corpuscles were seen. Significantly more free nerve endings (P < 0.001) and blood vessels (P = 0.01) were observed in the subtalar joint capsule than in the superficial part of the fat pad at the IER. The deep part of the fat pad at the IER had significantly more blood vessels than the superficial part of the fat pad at the IER (P = 0.012). Significantly more blood vessels than free nerve endings were seen in all three groups (P < 0.001). No significant differences in distribution were seen in terms of right or left side, except for free nerve endings in the superficial part of the fat pad at the IER (P = 0.003). A greater number of free nerve endings correlated with a greater number of blood vessels. The presence of sensory nerve endings between individual fat cells supports the hypothesis that the fat pad has a proprioceptive role monitoring changes and that it is a source of pain in sinus tarsi syndrome due to the abundance of free nerve endings. PMID:24472004

Histological Comparison of Cold versus Hot Snare Resections of the Colorectal Mucosa.

PubMed

Takayanagi, Daisuke; Nemoto, Daiki; Isohata, Noriyuki; Endo, Shungo; Aizawa, Masato; Utano, Kenichi; Kumamoto, Kensuke; Hojo, Hiroshi; Lefor, Alan Kawarai; Togashi, Kazutomo

2018-06-25

Delayed postpolypectomy bleeding occurs more frequently after hot resection than after cold resection. To elucidate the underlying mechanism, we performed a histological comparison of tissue after cold and hot snare resections. This is a prospective study, registered in the University Hospital Medical Information Network (UMIN000020104). This study was conducted at Aizu Medical Center, Fukushima Medical University, Japan. Fifteen patients scheduled to undergo resection of colorectal cancer were enrolled. On the day before surgery, 2 mucosal resections (hot and cold) of normal mucosa were performed on each patient using the same snare without saline injection. The difference was only the application of electrocautery or not. Resection sites were placed close to the cancer to be included in the surgical specimen. The primary outcome measure was the depth of destruction. Secondary outcome measures included the width of destruction, depth of the remaining submucosa, and number of vessels remaining at the resection sites. The number and diameter of vessels in undamaged submucosa were also evaluated. All cold resections were limited to the shallow submucosa, whereas 60% of hot resections advanced to the deep submucosa and 20% to the muscularis propria (p < 0.001). There was no significant difference in the width of destruction. The number of remaining large vessels after hot resections trended toward fewer (p = 0.15) with a decreased depth of remaining submucosa (p = 0.007). In the deep submucosa, the vessel diameter was larger (p < 0.001) and the number of large vessels was greater (p = 0.018). Histological assessment was not blinded to the 2 reviewers. Normal mucosa was used instead of adenomatous tissue. Hot resection caused damage to deeper layers involving more large vessels. This may explain the mechanism for the reduced incidence of hemorrhage after cold snare polypectomy. See Video Abstract at http://links.lww.com/DCR/A631.

Fracture toughness testing of Linde 1092 reactor vessel welds in the transition range using Charpy-sized specimens

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pavinich, W.A.; Yoon, K.K.; Hour, K.Y.

1999-10-01

The present reference toughness method for predicting the change in fracture toughness can provide over estimates of these values because of uncertainties in initial RT{sub NDT} and shift correlations. It would be preferable to directly measure fracture toughness. However, until recently, no standard method was available to characterize fracture toughness in the transition range. ASTM E08 has developed a draft standard that shows promise for providing lower bound transition range fracture toughness using the master curve approach. This method has been successfully implemented using 1T compact fracture specimens. Combustion Engineering reactor vessel surveillance programs do not have compact fracture specimens.more » Therefore, the CE Owners Group developed a program to validate the master curve method for Charpy-sized and reconstituted Charpy-sized specimens for future application on irradiated specimens. This method was validated for Linde 1092 welds using unirradiated Charpy-sized and reconstituted Charpy-sized specimens by comparison of results with those from compact fracture specimens.« less

Optics based signal processing methods for intraoperative blood vessel detection and quantification in real time (Conference Presentation)

NASA Astrophysics Data System (ADS)

Chaturvedi, Amal; Shukair, Shetha A.; Le Rolland, Paul; Vijayvergia, Mayank; Subramanian, Hariharan; Gunn, Jonathan W.

2016-03-01

Minimally invasive operations require surgeons to make difficult cuts to blood vessels and other tissues with impaired tactile and visual feedback. This leads to inadvertent cuts to blood vessels hidden beneath tissue, causing serious health risks to patients and a non-reimbursable financial burden to hospitals. Intraoperative imaging technologies have been developed, but these expensive systems can be cumbersome and provide only a high-level view of blood vessel networks. In this research, we propose a lean reflectance-based system, comprised of a dual wavelength LED, photodiode, and novel signal processing algorithms for rapid vessel characterization. Since this system takes advantage of the inherent pulsatile light absorption characteristics of blood vessels, no contrast agent is required for its ability to detect the presence of a blood vessel buried deep inside any tissue type (up to a cm) in real time. Once a vessel is detected, the system is able to estimate the distance of the vessel from the probe and the diameter size of the vessel (with a resolution of ~2mm), as well as delineate the type of tissue surrounding the vessel. The system is low-cost, functions in real-time, and could be mounted on already existing surgical tools, such as Kittner dissectors or laparoscopic suction irrigation cannulae. Having been successfully validated ex vivo, this technology will next be tested in a live porcine study and eventually in clinical trials.

630 A MARITIME NUCLEAR STEAM GENERATOR. Progress Report No. 2

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

1962-09-28

A layout of a reduced-height 630A assembly (34 to 23 ft) was prepared and is presently being evaluated for use in a merchant vessel. While shielding studies indicate the need for some rearrangement of the shield materials, the desired radiation constraint can be obtained without an increase in shielding weight. A preliminary stress analysis of the pressure vessel, flow path analysis, and insulation evaluation was completed and showed no major problems. Evaluation of the total containment design indicates a design pressure of 45 psig. The Critical Experiment (CE) mockup is about 80% complete. The CE tank and dolly is aboutmore » 50% complete. The CE hazards report was reviewed and approved. The draft of the test program and procedures document is 75% complete. The LPT control room modifications were made, and the draft of the standard operating procedures completed. The CE fuel was inspected and a significant portion was found to be of no use, about 60% requires recoating. Creep and oxidation test time on some of the fuel sheet has exceeded 3000 hr with no significant oxidation or elongation on any of the samples. The nickel -chromium alloy sheet high- temperature (1750 F) stress and oxidating testing have exceeded 5000 hr with elongations below 0.8% except for one sample of 2.3%. Experimental fuel sheet samples were prepared and comparative property studies were ini-tiated. Fabrication of the ring test assembly, 3-F-1, for test in the MTR is essentially complete. The design of the test ring for seal evaluations was initiated. A detailed schedule for the work in FY 63 was prepared and issued for comments and concurrence. (auth)« less

Skin regeneration in deep second-degree scald injuries either by infusion pumping or topical application of recombinant human erythropoietin gel.

PubMed

Giri, Priya; Ebert, Sabine; Braumann, Ulf-Dietrich; Kremer, Mathias; Giri, Shibashish; Machens, Hans-Günther; Bader, Augustinus

2015-01-01

Large doses of recombinant growth factors formulated in solution form directly injected into the body is usual clinical practice in treating second-degree scald injuries, with promising results, but this approach creates side effects; furthermore, it may not allow appropriate levels of the factor to be sensed by the target injured tissue/organ in the specific time frame, owing to complications arising from regeneration. In this research, two delivery methods (infusion pumping and local topical application) were applied to deliver recombinant human erythropoietin (rHuEPO) for skin regeneration. First, rHuEPO was given in deep second-degree scald injury sites in mice by infusion pump. Vascularization was remarkably higher in the rHuEPO pumping group than in controls. Second, local topical application of rHuEPO gel was given in deep second-degree scald injury sites in rats. Histological analysis showed that epithelialization rate was significantly higher in the rHuEPO gel-treated group than in controls. Immunohistochemical studies showed that the rHuEPO gel-treated group showed remarkably higher expression of skin regeneration makers than the control group. An accurate method for visualization and quantification of blood vessel networks in target areas has still not been developed up to this point, because of technical difficulties in detecting such thin blood vessels. A method which utilizes a series of steps to enhance the image, removes noise from image background, and tracks the vessels edges for vessel segmentation and quantification has been used in this study. Using image analysis methods, we were able to detect the microvascular networks of newly formed blood vessels (less than 500 μm thickness), which participate in the healing process, providing not only nutrition and oxygen to grow tissues but also necessary growth factors to grow tissue cells for complete skin regeneration. The rHuEPO-treated group showed higher expression of stem cell markers (CD 31, CD 90, CD 71, and nestin), which actively contribute to in-wound-healing processes for new hair follicle generation as well as skin regeneration. Collectively, both rHuEPO group pumping into the systemic circulation system, and injection into the local injury area, prompted mice and rats to form new blood vessel networks in scald injury sites, which significantly participate in the scald healing process. These results may lead to the development of novel treatments for scald wounds.

Skin regeneration in deep second-degree scald injuries either by infusion pumping or topical application of recombinant human erythropoietin gel

PubMed Central

Giri, Priya; Ebert, Sabine; Braumann, Ulf-Dietrich; Kremer, Mathias; Giri, Shibashish; Machens, Hans-Günther; Bader, Augustinus

2015-01-01

Large doses of recombinant growth factors formulated in solution form directly injected into the body is usual clinical practice in treating second-degree scald injuries, with promising results, but this approach creates side effects; furthermore, it may not allow appropriate levels of the factor to be sensed by the target injured tissue/organ in the specific time frame, owing to complications arising from regeneration. In this research, two delivery methods (infusion pumping and local topical application) were applied to deliver recombinant human erythropoietin (rHuEPO) for skin regeneration. First, rHuEPO was given in deep second-degree scald injury sites in mice by infusion pump. Vascularization was remarkably higher in the rHuEPO pumping group than in controls. Second, local topical application of rHuEPO gel was given in deep second-degree scald injury sites in rats. Histological analysis showed that epithelialization rate was significantly higher in the rHuEPO gel-treated group than in controls. Immunohistochemical studies showed that the rHuEPO gel-treated group showed remarkably higher expression of skin regeneration makers than the control group. An accurate method for visualization and quantification of blood vessel networks in target areas has still not been developed up to this point, because of technical difficulties in detecting such thin blood vessels. A method which utilizes a series of steps to enhance the image, removes noise from image background, and tracks the vessels edges for vessel segmentation and quantification has been used in this study. Using image analysis methods, we were able to detect the microvascular networks of newly formed blood vessels (less than 500 μm thickness), which participate in the healing process, providing not only nutrition and oxygen to grow tissues but also necessary growth factors to grow tissue cells for complete skin regeneration. The rHuEPO-treated group showed higher expression of stem cell markers (CD 31, CD 90, CD 71, and nestin), which actively contribute to in-wound-healing processes for new hair follicle generation as well as skin regeneration. Collectively, both rHuEPO group pumping into the systemic circulation system, and injection into the local injury area, prompted mice and rats to form new blood vessel networks in scald injury sites, which significantly participate in the scald healing process. These results may lead to the development of novel treatments for scald wounds. PMID:26005333

Marine Seismic System Deployment (MSS). Phase 2. Investigation of Techniques and Deployment Scenarios for Installation of Triaxial Seismometer in a Borehole in the Deep Ocean

DTIC Science & Technology

1981-01-09

CHALLENGER for an estimated period of six days. The design for the test Borehole Instrumentation Package (BIP) reentry-sub and associated handling...equipment has been completed ard hmi been submitted for vendor bid. Details of the specialized support equipment for installation on the GLOMAR CHALLENGER ...developed under the direction of the Deep Sea Drilling Project (DSDP) by the dynamically positioned drilling vessel GLOMAR CHALLENGER . Deployment of the

ANME-2D Archaea Catalyze Methane Oxidation in Deep Subsurface Sediments Independent of Nitrate Reduction

NASA Astrophysics Data System (ADS)

Hernsdorf, A. W.; Amano, Y.; Suzuki, Y.; Ise, K.; Thomas, B. C.; Banfield, J. F.

2015-12-01

Terrestrial sediments are an important global reservoir for methane. Microorganisms in the deep subsurface play a critical role in the methane cycle, yet much remains to be learned about their diversity and metabolisms. To provide more comprehensive insight into the microbiology of the methane cycle in the deep subsurface, we conducted a genome-resolved study of samples collected from the Horonobe Underground Research Laboratory (HURL), Japan. Groundwater samples were obtained from three boreholes from a depth range of between 140 m and 250 m in two consecutive years. Groundwater was filtered and metagenomic DNA extracted and sequenced, and the sequence data assembled. Based on the sequences of phylogenetically informative genes on the assembled fragments, we detected a high degree of overlap in community composition across a vertical transect within one borehole at the two sampling times. However, there was comparatively little similarity observed among communities across boreholes. Spatial and temporal abundance patterns were used in combination with tetranucleotide signatures of assembled genome fragments to bin the data and reconstruct over 200 unique draft genomes, of which 137 are considered to be of high quality (>90% complete). The deepest samples from one borehole were highly dominated by an archaeon identified as ANME-2D; this organism was also present at lower abundance in all other samples from that borehole. Also abundant in these microbial communities were novel members of the Gammaproteobacteria, Saccharibacteria (TM7) and Tenericute phyla. Notably, a ~2 Mbp draft genome for the ANME-2D archaeon was reconstructed. As expected, the genome encodes all of the genes predicted to be involved in the reverse methanogenesis pathway. In contrast with the previously reported ANME2-D genome, the HURL ANME-2D genome lacks the capacity to reduce nitrate. However, we identified many multiheme cytochromes with closest similarity to those of the known Fe-reducing/oxidizing archaeon Ferroglobus placidus. Thus, we suggest that ANME2-D may couple methane oxidation to reduction of ferric iron minerals in the sediment and may be generally important as a link between the iron and methane cycles in deep subsurface environments. Such information has important implications for modeling the global carbon cycle.

Proof test criteria for thin-walled 2219 aluminum pressure vessels. Volume 1: Program summary and data analysis

NASA Technical Reports Server (NTRS)

Finger, R. W.

1976-01-01

This experimental program was undertaken to investigate the crack growth behavior of deep surface flaws in 2219 aluminum. The program included tests of uniaxially loaded surface flaw and center crack panels at temperatures ranging from 20K (-423 F) to ambient. The tests were conducted on both the base metal and as-welded weld metal material. The program was designed to provide data on the mechanisms of failure by ligament penetration, and the residual cyclic life, after proof-testing, of a vessel which has been subjected to incipient penetration by the proof test. The results were compared and analyzed with previously developed data to develop guidelines for the proof testing of thin walled 2219 pressure vessels.

Study on Vortex-Induced Motions of A New Type of Deep Draft Multi-Columns FDPSO

NASA Astrophysics Data System (ADS)

Gu, Jia-yang; Xie, Yu-lin; Zhao, Yuan; Li, Wen-juan; Tao, Yan-wu; Huang, Xiang-hong

2018-03-01

A numerical simulation and an experimental study on vortex-induced motion (VIM) of a new type of deep draft multi-columns floating drilling production, storage and offloading (FDPSO) are presented in this paper. The main dimension, the special variable cross-section column and the cabin arrangement of the octagonal pontoon are introduced based on the result. The numerical simulation is adapted to study the effects of current incidence angles and reduced velocities on this platform's sway motion response. The 300 m water depth equivalent truncated mooring system is adopted for the model tests. The model tests are carried out to check the reliability of numerical simulation. The results consist of surge, sway and yaw motions, as well as motion trajectories. The maximum sway amplitudes for different types of offshore platform is also studied. The main results show that the peak frequencies of sway motion under different current incidence angles and reduced velocities vary around the natural frequency. The analysis result of flow field indicates that the change of distribution of vortex in vertical presents significant influences on the VIM of platform. The trend of sway amplitude ratio curve of this new type FDPSO differs from the other types of platform. Under 45° current incidence angle, the sway amplitude of this new type of FDPSO is much smaller than those of other types of offshore platform at 4.4 ≤ V r ≤ 8.9. The typical `8' shape trajectory does not appear in the platform's motion trajectories.

[Identification of perforating vessels by augmented reality: Application for the deep inferior epigastric perforator flap].

PubMed

Bosc, R; Fitoussi, A; Pigneur, F; Tacher, V; Hersant, B; Meningaud, J-P

2017-08-01

The augmented reality on smart glasses allows the surgeon to visualize three-dimensional virtual objects during surgery, superimposed in real time to the anatomy of the patient. This makes it possible to preserve the vision of the surgical field and to dispose of added computerized information without the need to use a physical surgical guide or a deported screen. The three-dimensional objects that we used and visualized in augmented reality came from the reconstructions made from the CT-scans of the patients. These objects have been transferred through a dedicated application on stereoscopic smart glasses. The positioning and the stabilization of the virtual layers on the anatomy of the patients were obtained thanks to the recognition, by the glasses, of a tracker placed on the skin. We used this technology, in addition to the usual locating methods for preoperative planning and the selection of perforating vessels for 12 patients operated on a breast reconstruction, by perforating flap of deep lower epigastric artery. The "hands-free" smart glasses with two stereoscopic screens make it possible to provide the reconstructive surgeon with binocular visualization in the operative field of the vessels identified with the CT-scan. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

Construction Progress and Science Planning for the New Research Vessel R/V Sikuliaq

NASA Astrophysics Data System (ADS)

Whitledge, T. E.

2011-12-01

The research vessel R/V Sikuliaq (pronounced [see-KOO-lee-auk]) is currently being constructed on behalf of the NSF to support future scientific studies in high latitude waters. The 261 foot global class vessel will be capable of breaking 2.5 foot thick ice at 2 knots with an endurance of 45 days at sea and cruising at 11 knots. The R/V Sikuliaq will have a beam of 52 feet and a draft of 18.9 feet that will carry 26 scientists and a crew of 20. Berthing accommodations are a combination of single/double rooms with one stateroom and the common areas of the vessel are designed for ADA access and accommodations. The total laboratory space (main, analytical, electronics, wet, upper, and Baltic room will be 2100 square feet. The 4360 square foot working deck that is approximately 70 feet in length will accommodate 2-4 vans and multiple science operations. The vessel design strives to have the lowest possible environmental impact, including a low underwater-radiated noise signature. The science systems are prescribed to be state-of-the-art for bottom mapping, over-the-side "hands free" gear handling, broad band communications and scientific walk-in freezer and environmental chamber. More details and photos of the construction progress are available on the website at www.sfos.uaf.edu/arrv. The tentative shipyard schedule has a launch date of June 2012 and delivery to the University of Alaska Fairbanks in June 2013. Scientific operations following trials and testing is planned to start in January 2014. A Sikuliaq science planning workshop has been arranged for 18-19 February 2012 in Salt Lake City, UT just prior to the 2012 Ocean Sciences meeting. Interested participants should contact Terry Whitledge (terry@ims.uaf.edu).

AURORA BOREALIS - European Research Icebreaker With Drilling Capability

NASA Astrophysics Data System (ADS)

Biebow, N.; Lembke-Jene, L.; Kunz-Pirrung, M.; Thiede, J.

2008-12-01

The polar oceans are the least known areas of the globe, in although they hold the key to many of our climate´s secrets. How does the sea ice coverage and the sea water properties change? How do plants and animals survive under the most extreme conditions of the earth? Which information of past climate change can be read from the sediments at the sea-floor and how can the future changing climate be predicted? In order to answer such and further questions, for the moment a hypermodern research vessel, the AURORA BOREALIS, is planned, which can handle the cool summers and freezing winters of the polar oceans and which can drill deep into the sea floor. AURORA BOREALIS will be the most advanced Research Icebreaker in the world with a multi-functional role of drilling in deep ocean basins and supporting climate/environmental research and decision support for stakeholder governments for the next 35-40 years. It will have a high icebreaking capacity to penetrate autonomously (single ship operation) into the central Arctic Ocean with more than 2.5 meters of ice cover, during all seasons of the year. The new technological features will include dynamic positioning in closed sea- ice cover, satellite navigation and ice-management support and the deployment and operation of Remotely Operated Vehicles (ROV) and Autonomous Underwater Vehicles (AUVs) from the twin moon-pools. A unique feature of the vessel is the deep-sea drilling rig, which will enable sampling of the ocean floor and sub-sea up to 5000 m water and 1000 m penetration at the most inhospitable places on earth. The drilling capability will be deployed in both Polar Regions on the long run and AURORA BOREALIS will be the only vessel worldwide that could undertake this type of scientific investigation.

Non-Axisymmetric Inflatable Pressure Structure (NAIPS) Concept that Enables Mass Efficient Packageable Pressure Vessels with Sealable Openings

NASA Technical Reports Server (NTRS)

Doggett, William R.; Jones, Thomas C.; Kenner, Winfred S.; Moore, David F.; Watson, Judith J.; Warren, Jerry E.; Makino, Alberto; Yount, Bryan; Selig, Molly; Shariff, Khadijah;

Risk factors for computed tomography angiography spot sign in deep and lobar intracerebral hemorrhage are shared.

PubMed

Radmanesh, Farid; Falcone, Guido J; Anderson, Christopher D; Battey, Thomas W K; Ayres, Alison M; Vashkevich, Anastasia; McNamara, Kristen A; Schwab, Kristin; Romero, Javier M; Viswanathan, Anand; Greenberg, Steven M; Goldstein, Joshua N; Rosand, Jonathan; Brouwers, H Bart

2014-06-01

Patients with intracerebral hemorrhage (ICH) who present with a spot sign on computed tomography angiography are at increased risk of hematoma expansion and poor outcome. Because primary ICH is the acute manifestation of chronic cerebral small vessel disease, we investigated whether different clinical or imaging characteristics predict spot sign presence, using ICH location as a surrogate for arteriolosclerosis- and cerebral amyloid angiopathy-related ICH. Patients with primary ICH and available computed tomography angiography at presentation were included. Predictors of spot sign were assessed using uni- and multivariable regression, stratified by ICH location. Seven hundred forty-one patients were eligible, 335 (45%) deep and 406 (55%) lobar ICH. At least one spot sign was present in 76 (23%) deep and 102 (25%) lobar ICH patients. In multivariable regression, warfarin (odds ratio [OR], 2.42; 95% confidence interval [CI], 1.01-5.71; P=0.04), baseline ICH volume (OR, 1.20; 95% CI, 1.09-1.33, per 10 mL increase; P<0.001), and time from symptom onset to computed tomography angiography (OR, 0.89; 95% CI, 0.80-0.96, per hour; P=0.009) were associated with the spot sign in deep ICH. Predictors of spot sign in lobar ICH were warfarin (OR, 3.95; 95% CI, 1.87-8.51; P<0.001) and baseline ICH volume (OR, 1.20; 95% CI, 1.10-1.31, per 10 mL increase; P<0.001). The most potent associations with spot sign are shared between deep and lobar ICH, suggesting that the acute bleeding process that arises in the setting of different chronic small vessel diseases shares commonalities. © 2014 American Heart Association, Inc.

Undecompressed microbial populations from the deep sea.

PubMed Central

Jannasch, H J; Wirsen, C O; Taylor, C D

1976-01-01

Metabolic transformations of glutamate and Casamino Acids by natural microbial populations collected from deep waters (1,600 to 3,100 m) were studied in decompressed and undecompressed samples. Pressure-retaining sampling/incubation vessels and appropriate subsampling/incubation vessels and appropriate subsampling techniques permitted time course experiments. In all cases the metabolic activity in undecompressed samples was lower than it was when incubated at 1 atm. Surface water controls showed a reduced activity upon compression. The processes involving substrate incorporation into cell material were more pressure sensitive than was respiration. The low utilization of substrates, previously found by in situ incubations for up to 12 months, was confirmed and demonstrated to consist of an initial phase of activity, in the range of 5 to 60 times lower than the controls, followed by a stationary phase of virtually no substrate utilization. No barophilic growth response (higher rates at elevated pressure than at 1 atm) was recorded; all populations observed exhibition various degrees of barotolerance. Images PMID:791117

Broadband calibration of the R/V Marcus G. Langseth four-string seismic sources

NASA Astrophysics Data System (ADS)

Tolstoy, M.; Diebold, J.; Doermann, L.; Nooner, S.; Webb, S. C.; Bohnenstiehl, D. R.; Crone, T. J.; Holmes, R. C.

2009-08-01

The R/V Marcus G. Langseth is the first 3-D seismic vessel operated by the U.S. academic community. With up to a four-string, 36-element source and four 6-km-long solid state hydrophone arrays, this vessel promises significant new insights into Earth science processes. The potential impact of anthropogenic sound sources on marine life is an important topic to the marine seismic community. To ensure that operations fully comply with existing and future marine mammal permitting requirements, a calibration experiment was conducted in the Gulf of Mexico in 2007-2008. Results are presented from deep (˜1.6 km) and shallow (˜50 m) water sites, obtained using the full 36-element (6600 cubic inches) seismic source. This array configuration will require the largest safety radii, and the deep and shallow sites provide two contrasting operational environments. Results show that safety radii and the offset between root-mean-square and sound exposure level measurements were highly dependent on water depth.

"Deep-media culture condition" promoted lumen formation of endothelial cells within engineered three-dimensional tissues in vitro.

PubMed

Sekiya, Sachiko; Shimizu, Tatsuya; Yamato, Masayuki; Okano, Teruo

2011-03-01

In the field of tissue engineering, the induction of microvessels into tissues is an important task because of the need to overcome diffusion limitations of oxygen and nutrients within tissues. Powerful methods to create vessels in engineered tissues are needed for creating real living tissues. In this study, we utilized three-dimensional (3D) highly cell dense tissues fabricated by cell sheet technology. The 3D tissue constructs are close to living-cell dense tissue in vivo. Additionally, creating an endothelial cell (EC) network within tissues promoted neovascularization promptly within the tissue after transplantation in vivo. Compared to the conditions in vivo, however, common in vitro cell culture conditions provide a poor environment for creating lumens within 3D tissue constructs. Therefore, for determining adequate conditions for vascularizing engineered tissue in vitro, our 3D tissue constructs were cultured under a "deep-media culture conditions." Compared to the control conditions, the morphology of ECs showed a visibly strained cytoskeleton, and the density of lumen formation within tissues increased under hydrostatic pressure conditions. Moreover, the increasing expression of vascular endothelial cadherin in the lumens suggested that the vessels were stabilized in the stimulated tissues compared with the control. These findings suggested that deep-media culture conditions improved lumen formation in engineered tissues in vitro.

Breathing synchronized assessment of the chest hemodynamics: application to gamma and MR angiography

NASA Astrophysics Data System (ADS)

Eclancher, Bernard; Demangeat, Jean-Louis; Germain, Philippe; Baruthio, Joseph

2003-05-01

The project was to assess by gamma and MR angiography the bulk variations of chest blood volume related to deep and slow breathing movements. The acquisitions were performed at constant intervals on the widely moving system, without cardiac gating. Two fast enough modalities were used: a gamma-stethoscope working at 30 msec intervals for bulk volumic detection (of 99Tc labelled red cells), and MR imaging at 0.5 sec intervals well depicting displacements but not yet performing true angiography. The third modality yielding quantitative imaging was the scintillation gamma camera, but which required 30 sec signal acquisitions for each image. Frames were acquired at 1 sec intervals for up to 30 breathing cycles, and later sorted with double (inspiration and expiration) synchronization for the reconstruction of an average breathing cycle. Convergent results were obtained from the three angiographic modalities, confirming that the deep breathing movements produced inspiratory increases in bulk blood volume and caudal-median displacement of heart and great vessels, and expiratory decreases in blood volume and cranial-left displacement of heart and great vessels. Deep and slow breathing contributed effectively to thoracic blood pumping. The design of a 64x64 channels collimator has been undertaken to speed up the scintillation camera imaging acquisitions.

Non-destructive inspection using HTS SQUID on aluminum liner covered by CFRP

NASA Astrophysics Data System (ADS)

Hatsukade, Y.; Yotsugi, K.; Sakaguchi, Y.; Tanaka, S.

2007-10-01

An eddy-current-based SQUID non-destructive inspection (NDI) system to detect deep-lying cracks in multi-layer composite-Al vessels was developed taking advantage of the uncontested sensitivity of HTS-SQUID in low-frequency range. An HTS-SQUID gradiometer was mounted in a pulse tube cryocooler. A pair of differential coils with C-shaped ferrite cores was employed to induce an enhanced eddy current in an Al vessel wrapped in a carbon fiber reinforced plastic (CFRP) cover. Ellipsoidal dome-shaped Al liners containing through cracks, which were made by pressure cycle tests, in the CFRP covers with total thickness of 6 mm (CFPR 3 mm, and Al 3 mm) were inspected by the system. While inducing eddy currents in the vessels with excitation fields at 100 Hz or 7 kHz, the vessels were rotated under the HTS-SQUID. Above the cracks, anomalous signals due to the cracks were clearly detected at both frequencies. These results suggested the SQUID-NDI technique would be a possible candidate for inspection of high-pressure multi-layer composite-Al vessels.

Pascagoula Harbor, Mississippi. Feasibility Report on Improvement of the Federal Deep-Draft Navigation Channel. Volume 2. Technical Appendices. Revision.

DTIC Science & Technology

1985-03-01

about half the time as the pipeline work, it would be logical for that work to begin about the middle of the period so all construction would finish ...d co)uld 𔃾’ -I to -rilch a plan i t c t C , . vy -;i- .: i m ’i, end o Iit coton . -p m -w 1u d ’if n;i ii 1 1in, ne, f e eco an .. i gil im 7" i

Oakland Harbor. Deep-Draft Navigation Improvements. Design Memorandum Number 1, General Design and Final Supplement 1 to the Environmental Impact Statement, Alameda County, California.

DTIC Science & Technology

1988-03-01

presentations to the Panal , the Department of the Navy’s restrictions on submarine operating areas were mentioned, iniating that the Nxwy opposed...impacts of dredged material disposal and/or till gaps in data. Panal .fUtrugtgra and Oranh~AtaoAin The panel is comprised of five representatives from 2A...riverine inflow is the low and prevailing winds from the west or northwest are augmented by daily pressure gradient induced movement of air due to solar

The Hematopoietic Stem Cell Therapy for Exploration of Deep Space

NASA Technical Reports Server (NTRS)

Ohi, Seigo; Roach, Allana-Nicole; Fitzgerald, Wendy; Riley, Danny A.; Gonda, Steven R.

2003-01-01

It is hypothesized that the hematopoietic stem cell therapy (HSCT) might countermeasure various space-caused disorders so as to maintain astronauts' homeostasis. If this were achievable, the HSCT could promote human exploration of deep space. Using animal models of disorders (hindlimb suspension unloading system and beta-thalassemia), the HSCT was tested for muscle loss, immunodeficiency and space anemia. The results indicate feasibility of HSCT for these disorders. To facilitate the HSCT in space, growth of HSCs were optimized in the NASA Rotating Wall Vessel (RWV) culture systems, including Hydrodynamic Focusing Bioreactor (HFB).

40 CFR Table Jj-7 to Subpart Jj of... - Nitrous Oxide Emission Factors (kg N2O-N/kg Kjdl N)

Code of Federal Regulations, 2011 CFR

2011-07-01

...) 0.07 Deep bedding for cattle and swine (no mix) 0.01 Manure Composting (in vessel) 0.006 Manure Composting (intensive) 0.1 Manure Composting (passive) 0.01 Manure Composting (static) 0.006 Aerobic...

50 CFR 86.20 - What activities are eligible for funding?

Code of Federal Regulations, 2011 CFR

2011-10-01

... or privately owned boating infrastructure tie-up facilities. To be eligible you must: (1) Build these... nontrailerable recreational vessels; (3) Build these tie-up facilities in water deep enough for nontrailerable... fluctuation); (4) Provide security, safety, and service for these boats; and, (5) Install a pumpout station...

50 CFR 86.20 - What activities are eligible for funding?

Code of Federal Regulations, 2012 CFR

2012-10-01

... or privately owned boating infrastructure tie-up facilities. To be eligible you must: (1) Build these... nontrailerable recreational vessels; (3) Build these tie-up facilities in water deep enough for nontrailerable... fluctuation); (4) Provide security, safety, and service for these boats; and, (5) Install a pumpout station...

50 CFR 86.20 - What activities are eligible for funding?

Code of Federal Regulations, 2013 CFR

2013-10-01

... publicly or privately owned boating infrastructure tie-up facilities. To be eligible you must: (1) Build... transient nontrailerable recreational vessels; (3) Build these tie-up facilities in water deep enough for... of lowest fluctuation); (4) Provide security, safety, and service for these boats; and, (5) Install a...

15 CFR 971.1006 - Proprietary enforcement information.

Code of Federal Regulations, 2010 CFR

2010-01-01

... REGULATIONS OF THE ENVIRONMENTAL DATA SERVICE DEEP SEABED MINING REGULATIONS FOR COMMERCIAL RECOVERY PERMITS... or maintained under Title III of the Act concerning a person or vessel engaged in commercial recovery... Administrator will, consistent with due process, move to have records sealed, under 15 CFR part 904 subpart C...

The impact of the New Panama Canal Locks on Texas ports and the Texas economy.

DOT National Transportation Integrated Search

2017-10-01

This report examines the first year transits through the new Panama Canal locks and its impact on Texas deep water ports. It finds that the canal is operating efficiently and can accommodate 14,000 TEU containerships and bulk vessels up to 125,000 to...

46 CFR 154.439 - Tank design.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 5 2010-10-01 2010-10-01 false Tank design. 154.439 Section 154.439 Shipping COAST... SELF-PROPELLED VESSELS CARRYING BULK LIQUEFIED GASES Design, Construction and Equipment Independent Tank Type A § 154.439 Tank design. An independent tank type A must meet the deep tank standard of the...

46 CFR 154.439 - Tank design.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 5 2011-10-01 2011-10-01 false Tank design. 154.439 Section 154.439 Shipping COAST... SELF-PROPELLED VESSELS CARRYING BULK LIQUEFIED GASES Design, Construction and Equipment Independent Tank Type A § 154.439 Tank design. An independent tank type A must meet the deep tank standard of the...

Application Side Casing on Open Deck RoRo to Improve Ship Stability

NASA Astrophysics Data System (ADS)

Hasanudin; K. A. P Utama, I.; Chen, Jeng-Horng

2018-03-01

RoRo is a vessel that can transport passengers, cargo, container and cars. Open Car Deck is favourite RoRo Vessel in developing countries due to its small GT, small tax and spacious car deck, but it has poor survival of stability. Many accident involve Open Car Deck RoRo which cause fatalities and victim. In order to ensure the safety of the ship, IMO had applied intact stability criteria IS Code 2008 which adapted from Rahola’s Research, but since 2008 IMO improved criteria become probabilistic damage stability SOLAS 2009. The RoRo type Open Car Deck has wide Breadth (B), small Draft (D) and small freeboard. It has difficulties to satisfy the ship’s stability criteria. Side Casings which has been applied in some RoRo have be known reduce freeboard or improve ship’s safety. In this paper investigated the effect side casings to survival of intact dan damage ship’s stability. Calculation has been conducted for four ships without, existing and full side casings. The investigation results shows that defect stability of Open Deck RoRo can be reduce with fitting side casing.

The pressure ridge distribution in the Arctic Ocean from submarine sonar data

NASA Astrophysics Data System (ADS)

Rodrigues, Joao; Wadhams, Peter

2010-05-01

The profiling of the underside of the sea ice with upward-looking sonars fitted to submarines is the best method of studying the large scale distribution of morphological features such as pressure ridges and leads. We present the statistical analysis of the distributions of pressure ridge spacings and heights, and lead spacings and widths observed during two Arctic cruises by the Royal Navy submarine HMS Tireless in the winters of 2004 and 2007 in which more than 10000km of sea ice draft data were collected. We briefly describe the main characteristics of the full ice draft distribution in the several regions of the Arctic Ocean visited by the submarine and discuss the most significant differences between 2004 and 2007. In the area of heavily ridged ice north of Greenland and Ellesmere Island we found an increase in ridge density (number of ridges per unit track length) accompanied by a decrease in modal ice draft, leaving the mean ice thickness essentially unchanged, between 2004 and 2007. This area is likely to be the only one in the Arctic Ocean where the sea ice thickness may not be in decline. We investigate the causes of this invariance in the context of an Arctic Ocean in transition from a multi-year to a first-year ice cover and discuss its relation with the strengthening of the transpolar drift and consequent accumulation of ice north of Greenland and increase in ice export through Fram Strait. Our analysis shows that the number of deep ridges per km is well described by a Poisson distribution while the corresponding distribution for shallow ridges is more complicated. The tail of the distribution of the pressure ridge heights is approximately a negative exponential, in agreement with similar observations made in previous cruises. We pay special attention to the uncertainties and biases in the measurement of the ice draft. Specifically, we discuss the effects of the finite beamwidth of the single-beam sonars traditionally used in British submarines on the determination of sea ice draft, which may have been underestimated in previous work.

Histology-validated x-ray tomography for imaging human coronary arteries

NASA Astrophysics Data System (ADS)

Buscema, Marzia; Schulz, Georg; Deyhle, Hans; Khimchenko, Anna; Matviykiv, Sofiya; Holme, Margaret N.; Hipp, Alexander; Beckmann, Felix; Saxer, Till; Michaud, Katarzyna; Müller, Bert

2016-10-01

Heart disease is the number one cause of death worldwide. To improve therapy and patient outcome, the knowledge of anatomical changes in terms of lumen morphology and tissue composition of constricted arteries is crucial for designing a localized drug delivery to treat atherosclerosis disease. Traditional tissue characterization by histology is a pivotal tool, although it brings disadvantages such as vessel morphology modification during decalcification and slicing. X-ray tomography in absorption and phase contrast modes yields a deep understanding in blood vessel anatomy in healthy and diseased stages: measurements in absorption mode make visible highly absorbing tissue components including cholesterol plaques, whereas phase contrast tomography gains better contrast of the soft tissue components such as vessel walls. Established synchrotron radiation-based micro-CT techniques ensure high performance in terms of 3D visualization of highly absorbing and soft tissues.

Extended supraclavicular fasciocutaneous island flap based on the transverse cervical artery for head and neck reconstruction after cancer ablation.

PubMed

Chen, Wei-Liang; Zhang, Da-ming; Yang, Zhao-hui; Huang, Zhi-quan; Wang, Jian-guang; Zhang, Bin; Li, Jing-song

2010-10-01

This clinical study assessed a pedicled supraclavicular fasciocutaneous island flap (SFIF) based on the transverse cervical artery that was extended to include shoulder skin for reconstructing the head and neck. Pedicled SFIFs extended to include the shoulder skin based on the cutaneous feeder vessels and perforator vessels in the deep fascia of the transverse cervical artery were designed for 24 patients with defects of the head and neck after cancer ablation. Preoperative 3-dimensional computed tomographic angiography was performed in all patients. The patients consisted of 15 men and 9 women ranging in age from 24 to 73 years. The primary lesions included squamous cell carcinoma of the tongue, buccal mucosa, floor of the mouth, oropharynx, palate, and lower gingiva. Three-dimensional computed tomographic angiography showed that the transverse cervical artery arose from the thyrocervical trunk in 13 cases and from the subclavian artery in 11 cases. The diameter of the artery ranged from 0.15 to 0.24 cm. The size of flaps ranged from 4 × 8 cm to 6 × 12 cm, and the mean length of the vascular pedicle was approximately 18.5 cm. Of the flaps, 23 survived completely, for a success rate of 95.8%. Three patients underwent radiotherapy, and the follow-up period ranged from 3 to 12 months. One patient died of local tumor recurrence, and cervical recurrences developed in 3 patients. An SFIF extended to include the shoulder skin based on the cutaneous feeder vessels and perforator vessels in the deep fascia of the transverse cervical artery is a useful, viable option for defects of the head and neck after cancer ablation. Copyright © 2010 American Association of Oral and Maxillofacial Surgeons. Published by Elsevier Inc. All rights reserved.

Indian-Ink Perfusion Based Method for Reconstructing Continuous Vascular Networks in Whole Mouse Brain

PubMed Central

Xue, Songchao; Gong, Hui; Jiang, Tao; Luo, Weihua; Meng, Yuanzheng; Liu, Qian; Chen, Shangbin; Li, Anan

2014-01-01

The topology of the cerebral vasculature, which is the energy transport corridor of the brain, can be used to study cerebral circulatory pathways. Limited by the restrictions of the vascular markers and imaging methods, studies on cerebral vascular structure now mainly focus on either observation of the macro vessels in a whole brain or imaging of the micro vessels in a small region. Simultaneous vascular studies of arteries, veins and capillaries have not been achieved in the whole brain of mammals. Here, we have combined the improved gelatin-Indian ink vessel perfusion process with Micro-Optical Sectioning Tomography for imaging the vessel network of an entire mouse brain. With 17 days of work, an integral dataset for the entire cerebral vessels was acquired. The voxel resolution is 0.35×0.4×2.0 µm3 for the whole brain. Besides the observations of fine and complex vascular networks in the reconstructed slices and entire brain views, a representative continuous vascular tracking has been demonstrated in the deep thalamus. This study provided an effective method for studying the entire macro and micro vascular networks of mouse brain simultaneously. PMID:24498247

Development of deep drawn aluminum piston tanks

DOE Office of Scientific and Technical Information (OSTI.GOV)

Whitehead, J.C.; Bronder, R.L.; Kilgard, L.W.

1990-06-08

An aluminum piston tank has been developed for applications requiring lightweight, low cost, low pressure, positive-expulsion liquid storage. The 3 liter (183 in{sup 3}) vessel is made primarily from aluminum sheet, using production forming and joining operations. The development process relied mainly on pressurizing prototype parts and assemblies to failure, as the primary source of decision making information for driving the tank design toward its optimum minimum-mass configuration. Critical issues addressed by development testing included piston operation, strength of thin-walled formed shells, alloy choice, and joining the end cap to the seamless deep drawn can. 9 refs., 8 figs.

Concomitant Reconstruction of Arch Vessels during Repair of Aortic Dissection

PubMed Central

Nezic, Dusko; Vukovic, Petar; Jovanovic, Marko; Lozuk, Branko; Jagodic, Sinisa; Djukanovic, Bosko

2014-01-01

Surgery for acute aortic dissection is challenging, especially in cases of cerebral malperfusion. Should we perform only the aortic repair, or should we also reconstruct the arch vessels when they are severely affected by the disease process? Here we present a case of acute aortic dissection with multiple tears that involved the brachiocephalic artery and caused cerebral and right upper-extremity malperfusion. The patient successfully underwent complete replacement of the brachiocephalic artery and the aortic arch during deep hypothermic circulatory arrest, with antegrade cerebral protection. We have found this technique to be safe and reproducible for use in this group of patients. PMID:25120398

Concomitant reconstruction of arch vessels during repair of aortic dissection.

PubMed

Micovic, Slobodan; Nezic, Dusko; Vukovic, Petar; Jovanovic, Marko; Lozuk, Branko; Jagodic, Sinisa; Djukanovic, Bosko

2014-08-01

Surgery for acute aortic dissection is challenging, especially in cases of cerebral malperfusion. Should we perform only the aortic repair, or should we also reconstruct the arch vessels when they are severely affected by the disease process? Here we present a case of acute aortic dissection with multiple tears that involved the brachiocephalic artery and caused cerebral and right upper-extremity malperfusion. The patient successfully underwent complete replacement of the brachiocephalic artery and the aortic arch during deep hypothermic circulatory arrest, with antegrade cerebral protection. We have found this technique to be safe and reproducible for use in this group of patients.

Propylthiouracil-induced cutaneous vasculitis. Case presentation and review of the literature.

PubMed

Vasily, D B; Tyler, W B

1980-02-01

A patient had cutaneous vasculitis, leukopenia, and splenomegaly caused by the antithyroid drug, propylthiouracil. Histopathologic changes of acute vasculitis of the superficial and deep dermal blood vessels accompanied by fibrin thrombi formation were found in biopsy specimens of the cutaneous lesions. Direct immunofluorescence studies demonstrated IgM and C3 of the vessel walls suggesting immune complex deposition. The literature disclosed five cases with similar features associated with propylthiouracil therapy. Characteristic cutaneous findings include a recurrent, self-limited, symmetrical purpuric eruption that can involve the face or earlobes. Clinicians should recognize these changes as a cutaneous sign of a vasculitis associated with propylthiouracil therapy.

Come On Down! Galapagos Rift Expedition--Grades 7-8. Overview: Ocean Exploration.

ERIC Educational Resources Information Center

National Oceanic and Atmospheric Administration (DOC), Rockville, MD.

These activities are designed to teach about ocean exploration. Students are expected to research the development and implementation of a research vessel/vehicle used for deep ocean exploration, calculate the density of objects by determining the mass and volume, and construct a device that exhibits neutral buoyancy. The activity provides learning…

50 CFR 648.263 - Red crab possession and landing restrictions.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 50 Wildlife and Fisheries 10 2011-10-01 2011-10-01 false Red crab possession and landing... Management Measures for the Atlantic Deep-Sea Red Crab Fishery § 648.263 Red crab possession and landing restrictions. (a) Vessels issued limited access red crab permits. (1) [Reserved] (2) Conversion to whole crab...

46 CFR 15.855 - Cabin watchmen and fire patrolmen.

Code of Federal Regulations, 2010 CFR

2010-10-01

... other danger. (b) On a fish processing vessel of more than 100 gross tons, there must be a suitable....400(c) of this chapter. (2) All grills, broilers, and deep-fat fryers are fitted with a grease... alarms are located in each space with a through hull fitting below the deepest load waterline, a...

The hydrodynamics of dolphin drafting

PubMed Central

Weihs, Daniel

2004-01-01

Background Drafting in cetaceans is defined as the transfer of forces between individuals without actual physical contact between them. This behavior has long been surmised to explain how young dolphin calves keep up with their rapidly moving mothers. It has recently been observed that a significant number of calves become permanently separated from their mothers during chases by tuna vessels. A study of the hydrodynamics of drafting, initiated in the hope of understanding the mechanisms causing the separation of mothers and calves during fishing-related activities, is reported here. Results Quantitative results are shown for the forces and moments around a pair of unequally sized dolphin-like slender bodies. These include two major effects. First, the so-called Bernoulli suction, which stems from the fact that the local pressure drops in areas of high speed, results in an attractive force between mother and calf. Second is the displacement effect, in which the motion of the mother causes the water in front to move forwards and radially outwards, and water behind the body to move forwards to replace the animal's mass. Thus, the calf can gain a 'free ride' in the forward-moving areas. Utilizing these effects, the neonate can gain up to 90% of the thrust needed to move alongside the mother at speeds of up to 2.4 m/sec. A comparison with observations of eastern spinner dolphins (Stenella longirostris) is presented, showing savings of up to 60% in the thrust that calves require if they are to keep up with their mothers. Conclusions A theoretical analysis, backed by observations of free-swimming dolphin schools, indicates that hydrodynamic interactions with mothers play an important role in enabling dolphin calves to keep up with rapidly moving adult school members. PMID:15132740

Deep sea microbial fuel cell output as a proxy for microbial activity

NASA Astrophysics Data System (ADS)

Richter, K.; George, R.; Hardy, K. R.

2016-02-01

Abstract: Microbial fuel cells (MFCs) work by providing bacteria in anaerobic sediments with an electron acceptor (anode) that stimulates metabolism of organic matter. The buried anode is connected via control circuitry to a cathode exposed to oxygen in the overlying water. During metabolism, bacteria release hydrogen ions into the sediment and transfer electrons extra-cellularly to the anode, which eventually reduce dissolved oxygen at the cathode, forming water. The current is chiefly limited by the rate of microbial metabolism at the anode and serves as a proxy for microbial activity. The Office of Naval Research has encouraged development of microbial fuel cells in the marine environment at a number of academic and naval institutions and studies of important environmental parameters that affect fuel cell performance. Earlier work in shallow sediments of San Diego Bay showed that the most important environmental parameters that control fuel cell power output in San Diego Bay were total organic carbon in the sediment and seasonal water temperature. Current MFC work at SPAWAR includes extension of microbial fuel cell tests to the deep sea environment (>4000 m) and, in parallel, testing microbial fuel cells in the laboratory under deep sea conditions. We are pursuing a field efforts to deploy a microbial fuel cell in progressively deeper water, record in situ power and temperature over several weeks, and retrieve the fuel cell along with sediment samples for analysis. We are also pursuing a laboratory effort to build a matching microbial fuel cell in a pressure vessel capable of matching the pressure and temperature of deep water, and stocking the pressure vessel with deep water sediment in order to take measurements analogous to those in the field. We also hope to determine whether bacteria growing on the anode are different from bacteria growing in the bulk sediment via DNA analysis. The current progress and results from this work at SPAWAR will be presented.

Safely combining abdominoplasty with aggressive abdominal liposuction based on perforator vessels: technique and a review of 300 consecutive cases.

PubMed

Smith, Lane F; Smith, Lane F

2015-05-01

There continues to be controversy about performing abdominoplasty concurrently with abdominal liposuction. The concern is that liposuction on the already vascularly compromised abdominal flap will lead to increased complications and flap necrosis. The central abdomen is supplied by the epigastric system. If perforator vessels from this system are spared, the blood supply to the abdomen can be spared and liposuction should be able to be safely performed on the elevated abdominal flap. The purpose of this study was to evaluate the safety of abdominoplasty with concurrent abdominal liposuction when a perforator vessel is spared. A standard abdominoplasty was performed, sparing one or two perforator vessels from the deep superior epigastric artery system. A retrospective chart review of 300 consecutive patients who underwent abdominoplasty surgery combined with concurrent abdominal liposuction was performed. Complications, total volume of abdominal liposuction, and results were reviewed. The overall complication rate was 17.3 percent (52 patients). Sixteen percent (48 patients) suffered minor complications and 1.3 percent (four patients) suffered major complications. Abdominoplasty can be combined safely with concurrent abdominal liposuction when a perforator vessel is spared. The combination of concurrent liposuction with abdominoplasty showed no increase in complication rates when a perforator vessel was spared. The perforator vessels are located consistently in a 2-cm radius located 4 cm from the midline and 6 cm from the subcostal margin. The potential advantages of abdominoplasty with concurrent liposuction include a better postoperative cosmetic result. Therapeutic, IV.

Robotic surgery twice performed in the treatment of hilar cholangiocarcinoma with deep jaundice: delayed right hemihepatectomy following the right-hepatic vascular control.

PubMed

Zhu, Zhenyu; Liu, Quanda; Chen, Junzhou; Duan, Weihong; Dong, Maosheng; Mu, Peiyuan; Cheng, Di; Che, Honglei; Zhang, Tao; Xu, Xiaoya; Zhou, Ningxin

2014-10-01

To explore and find a new method to treat hilar cholangiocarcinoma with deep jaundice assisted by Da Vinci robot. A hilar cholangiocarcinoma patient of type Bismuch-Corlette IIIa was found with deep jaundice (total bilirubin: 635 µmol/L). On the first admission, we performed Da Vinci robotic surgery including drainage of left hepatic duct, dissection of right hepatic vessels (right portal vein and right hepatic artery), and placement of right-hepatic vascular control device. Three weeks later on the second admission when the jaundice disappeared we occluded right-hepatic vascular discontinuously for 6 days and then sustained later. On the third admission after 3 weeks of right-hepatic vascular control, the right hemihepatectomy was performed by Da Vinci robot for the second time. The future liver remnant after the right-hepatic vascular control increased from 35% to 47%. The volume of left lobe increased by 368 mL. When the total bilirubin and liver function were all normal, right hemihepatectomy was performed by Da Vinci robot 10 weeks after the first operation. The removal of atrophic right hepatic lobe with tumor in bile duct was found with no pathologic cancer remaining in the margin. The patient was followed up at our outpatient clinic every 3 months and no tumor recurrence occurs by now (1 y). Under the Da Vinci robotic surgical system, a programmed treatment can be achieved: first, the hepatic vessels were controlled gradually together with biliary drainage, which results in liver's partial atrophy and compensatory hypertrophy in the other part. Then a radical hepatectomy could be achieved. Such programmed hepatectomy provides a new treatment for patients of hilar cholangiocarcinoma with deep jaundice who have the possibility of radical heptolobectomy.

Modelling and parameterizing the influence of tides on ice-shelf melt rates

NASA Astrophysics Data System (ADS)

Jourdain, N.; Molines, J. M.; Le Sommer, J.; Mathiot, P.; de Lavergne, C.; Gurvan, M.; Durand, G.

2017-12-01

Significant Antarctic ice sheet thinning is observed in several sectors of Antarctica, in particular in the Amundsen Sea sector, where warm circumpolar deep waters affect basal melting. The later has the potential to trigger marine ice sheet instabilities, with an associated potential for rapid sea level rise. It is therefore crucial to simulate and understand the processes associated with ice-shelf melt rates. In particular, the absence of tides representation in ocean models remains a caveat of numerous ocean hindcasts and climate projections. In the Amundsen Sea, tides are relatively weak and the melt-induced circulation is stronger than the tidal circulation. Using a regional 1/12° ocean model of the Amundsen Sea, we nonetheless find that tides can increase melt rates by up to 36% in some ice-shelf cavities. Among the processes that can possibly affect melt rates, the most important is an increased exchange at the ice/ocean interface resulting from the presence of strong tidal currents along the ice drafts. Approximately a third of this effect is compensated by a decrease in thermal forcing along the ice draft, which is related to an enhanced vertical mixing in the ocean interior in presence of tides. Parameterizing the effect of tides is an alternative to the representation of explicit tides in an ocean model, and has the advantage not to require any filtering of ocean model outputs. We therefore explore different ways to parameterize the effects of tides on ice shelf melt. First, we compare several methods to impose tidal velocities along the ice draft. We show that getting a realistic spatial distribution of tidal velocities in important, and can be deduced from the barotropic velocities of a tide model. Then, we explore several aspects of parameterized tidal mixing to reproduce the tide-induced decrease in thermal forcing along the ice drafts.

Lacunar infarction and small vessel disease: pathology and pathophysiology.

PubMed

Caplan, Louis R

2015-01-01

Two major vascular pathologies underlie brain damage in patients with disease of small size penetrating brain arteries and arterioles; 1) thickening of the arterial media and 2) obstruction of the origins of penetrating arteries by parent artery intimal plaques. The media of these small vessels may be thickened by fibrinoid deposition and hypertrophy of smooth muscle and other connective tissue elements that accompanies degenerative changes in patients with hypertension and or diabetes or can contain foreign deposits as in amyloid angiopathy and genetically mediated conditions such as cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy. These pathological changes lead to 2 different pathophysiologies: 1) brain ischemia in regions supplied by the affected arteries. The resultant lesions are deep small infarcts, most often involving the basal ganglia, pons, thalami and cerebral white matter. And 2) leakage of fluid causing edema and later gliosis in white matter tracts. The changes in the media and adventitia effect metalloproteinases and other substances within the matrix of the vessels and lead to abnormal blood/brain barriers in these small vessels. and chronic gliosis and atrophy of cerebral white matter.

A Research Program of Spherical Tokamak in China

NASA Astrophysics Data System (ADS)

He, Ye-xi

2002-08-01

The mission of this program is to explore the spherical torus plasma with a SUNIST spherical tokamak. Main experiments in the start phase will be involved with breakdown and plasma current set-up with a mode of saving volt-second and without ohmic heating system, equilibrium and instability, current driving, heating and profile modification. The SUNIST is a university-scale conceptual spherical tokamak, with R = 0.3 m, A 1.3, Ip ~ 50 kA, BT < 0.15 T, and PRF = 100 kW. The only peculiarity of SUNIST is that there is a toroidal insulating break along the outer wall of vacuum vessel. The expected that advantages of this arrangement are helpful not only for saving flux swing, but also for having a deep understanding of what will influence the discharge startup and globe performances of plasma under different conditions of strong vessel eddy and ECR power assistance. Of course, the vessel structure of cross seal will be at a great risk of controlling vacuum quality, although we have achieved positive results on simulation test and vacuum vessel test.

3D morphological analysis of the mouse cerebral vasculature: Comparison of in vivo and ex vivo methods

PubMed Central

Steinman, Joe; Koletar, Margaret M.; Stefanovic, Bojana; Sled, John G.

2017-01-01

Ex vivo 2-photon fluorescence microscopy (2PFM) with optical clearing enables vascular imaging deep into tissue. However, optical clearing may also produce spherical aberrations if the objective lens is not index-matched to the clearing material, while the perfusion, clearing, and fixation procedure may alter vascular morphology. We compared in vivo and ex vivo 2PFM in mice, focusing on apparent differences in microvascular signal and morphology. Following in vivo imaging, the mice (four total) were perfused with a fluorescent gel and their brains fructose-cleared. The brain regions imaged in vivo were imaged ex vivo. Vessels were segmented in both images using an automated tracing algorithm that accounts for the spatially varying PSF in the ex vivo images. This spatial variance is induced by spherical aberrations caused by imaging fructose-cleared tissue with a water-immersion objective. Alignment of the ex vivo image to the in vivo image through a non-linear warping algorithm enabled comparison of apparent vessel diameter, as well as differences in signal. Shrinkage varied as a function of diameter, with capillaries rendered smaller ex vivo by 13%, while penetrating vessels shrunk by 34%. The pial vasculature attenuated in vivo microvascular signal by 40% 300 μm below the tissue surface, but this effect was absent ex vivo. On the whole, ex vivo imaging was found to be valuable for studying deep cortical vasculature. PMID:29053753

Parametrization and evaluation of marine environmental impacts produced by deep-sea manganese nodule mining

NASA Astrophysics Data System (ADS)

Oebius, Horst U.; Becker, Hermann J.; Rolinski, Susanne; Jankowski, Jacek A.

The evaluation of marine environmental impacts resulting from the exploitation of marine resources requires the numerical description, parametrization, and modelling of such processes in order to be able to transfer, compare, and forecast the effects of anthropogenic activities in the deep sea. One of the controversial effects is the formation and behaviour of sediment clouds as a consequence of anthropogenic activities on the seafloor. Since there is a need for reliable data, two subprojects of the "Interdisciplinary Deep-sea Environmental Protection Group (TUSCH)"-project "Impacts from Technical Activities on the Deep-Sea Ecosystem of the South East Pacific Offshore Peru (ATESEPP)" were devoted to the assembly of such data. Based on the German technical approach for deep-sea mining, the possible environmental impacts by a miner were estimated, the impacts on the seafloor were simulated and investigated by tests with large volume undisturbed sediment samples on board the research vessel and in the laboratory, and the results were evaluated and extrapolated. This report gives a comprehensive presentation of the physical problems, the technical approach, and the results of these investigations.

Fire Safety Tests for Cesium-Loaded Spherical Resorcinol Formaldehyde Resin: Data Summary Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kim, Dong-Sang; Schweiger, Michael J.; Peterson, Reid A.

2012-09-01

A draft safety evaluation of the scenario for spherical resorcinol formaldehyde (SRF) resin fire inside the ion exchange column was performed by the Hanford Tank Waste Treatment and Immobilization Plant (WTP) Fire Safety organization. The result of this draft evaluation suggested a potential change of the fire safety classification for the Cesium Ion Exchange Process System (CXP) emergency elution vessels, equipment, and piping. To resolve this question, the fire properties of the SRF resin were measured by Southwest Research Institute (SwRI) through a subcontract managed by Pacific Northwest National Laboratory (PNNL). The results of initial fire safety tests on themore » SRF resin were documented in a previous report (WTP-RPT-218). The present report summarizes the results of additional tests performed by SwRI on the cesium-loaded SRF resin. The efforts by PNNL were limited to summarizing the test results provided by SwRI into one consolidated data report. The as-received SwRI report is attached to this report in the Appendix A. Where applicable, the precision and bias of each test method, as given by each American Society for Testing and Materials (ASTM) standard procedure, are included and compared with the SwRI test results of the cesium-loaded SRF resin.« less

Genomic characterization of symbiotic mycoplasmas from the stomach of deep-sea isopod bathynomus sp.

PubMed

Wang, Yong; Huang, Jiao-Mei; Wang, Shao-Lu; Gao, Zhao-Ming; Zhang, Ai-Qun; Danchin, Antoine; He, Li-Sheng

2016-09-01

Deep-sea isopod scavengers such as Bathynomus sp. are able to live in nutrient-poor environments, which is likely attributable to the presence of symbiotic microbes in their stomach. In this study we recovered two draft genomes of mycoplasmas, Bg1 and Bg2, from the metagenomes of the stomach contents and stomach sac of a Bathynomus sp. sample from the South China Sea (depth of 898 m). Phylogenetic trees revealed a considerable genetic distance to other mycoplasma species for Bg1 and Bg2. Compared with terrestrial symbiotic mycoplasmas, the Bg1 and Bg2 genomes were enriched with genes encoding phosphoenolpyruvate-dependent phosphotransferase systems (PTSs) and sodium-driven symporters responsible for the uptake of sugars, amino acids and other carbohydrates. The genome of mycoplasma Bg1 contained sialic acid lyase and transporter genes, potentially enabling the bacteria to attach to the stomach sac and obtain organic carbons from various cell walls. Both of the mycoplasma genomes contained multiple copies of genes related to proteolysis and oligosaccharide degradation, which may help the host survive in low-nutrient conditions. The discovery of the different types of mycoplasma bacteria in the stomach of this deep-sea isopod affords insights into symbiotic model of deep-sea animals and genomic plasticity of mycoplasma bacteria. © 2016 Society for Applied Microbiology and John Wiley & Sons Ltd.

Contrasts in Arctic shelf sea-ice regimes and some implications: Beaufort Sea versus Laptev Sea

USGS Publications Warehouse

Reimnitz, E.; Dethleff, D.; Nurnberg, D.

1994-01-01

The winter ice-regime of the 500 km) from the mainland than in the Beaufort Sea. As a result, the annual freeze-up does not incorporate old, deep-draft ice, and with a lack of compression, such deep-draft ice is not generated in situ, as on the Beaufort Sea shelf. The Laptev Sea has as much as 1000 km of fetch at the end of summer, when freezing storms move in and large (6 m) waves can form. Also, for the first three winter months, the polynya lies inshore at a water depth of only 10 m. Turbulence and freezing are excellent conditions for sediment entrainment by frazil and anchor ice, when compared to conditions in the short-fetched Beaufort Sea. We expect entrainment to occur yearly. Different from the intensely ice-gouged Beaufort Sea shelf, hydraulic bedforms probably dominate in the Laptev Sea. Corresponding with the large volume of ice produced, more dense water is generated in the Laptev Sea, possibly accompanied by downslope sediment transport. Thermohaline convection at the midshelf polynya, together with the reduced rate of bottom disruption by ice keels, may enhance benthic productivity and permit establishment of open-shelf benthic communities which in the Beaufort Sea can thrive only in the protection of barrier islands. Indirect evidence for high benthic productivity is found in the presence of walrus, who also require year-round open water. By contrast, lack of a suitable environment restricts walrus from the Beaufort Sea, although over 700 km farther to the south. We could speculate on other consequences of the different ice regimes in the Beaufort and Laptev Seas, but these few examples serve to point out the dangers of exptrapolating from knowledge gained in the North American Arctic to other shallow Arctic shelf settings. ?? 1994.

Relationship between Pipeline Wall Thickness (Gr. X60) and Water Depth towards Avoiding Failure during Installation

NASA Astrophysics Data System (ADS)

Razak, K. Abdul; Othman, M. I. H.; Mat Yusuf, S.; Fuad, M. F. I. Ahmad; yahaya, Effah

2018-05-01

Oil and gas today being developed at different water depth characterized as shallow, deep and ultra-deep waters. Among the major components involved during the offshore installation is pipelines. Pipelines are a transportation method of material through a pipe. In oil and gas industry, pipeline come from a bunch of line pipe that welded together to become a long pipeline and can be divided into two which is gas pipeline and oil pipeline. In order to perform pipeline installation, we need pipe laying barge or pipe laying vessel. However, pipe laying vessel can be divided into two types: S-lay vessel and J-lay vessel. The function of pipe lay vessel is not only to perform pipeline installation. It also performed installation of umbilical or electrical cables. In the simple words, pipe lay vessel is performing the installation of subsea in all the connecting infrastructures. Besides that, the installation processes of pipelines require special focus to make the installation succeed. For instance, the heavy pipelines may exceed the lay vessel’s tension capacities in certain kind of water depth. Pipeline have their own characteristic and we can group it or differentiate it by certain parameters such as grade of material, type of material, size of diameter, size of wall thickness and the strength. For instances, wall thickness parameter studies indicate that if use the higher steel grade of the pipelines will have a significant contribution in pipeline wall thickness reduction. When running the process of pipe lay, water depth is the most critical thing that we need to monitor and concern about because of course we cannot control the water depth but we can control the characteristic of the pipe like apply line pipe that have wall thickness suitable with current water depth in order to avoid failure during the installation. This research will analyse whether the pipeline parameter meet the requirements limit and minimum yield stress. It will overlook to simulate pipe grade API 5L X60 which size from 8 to 20mm thickness with a water depth of 50 to 300m. Result shown that pipeline installation will fail from the wall thickness of 18mm onwards since it has been passed the critical yield percentage.

76 FR 65155 - Fisheries Off West Coast States; Highly Migratory Species Fisheries; Swordfish Retention Limits

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-20

... retention limits for swordfish, Xiphias gladius, harvested in the U.S. West Coast-based deep-set tuna..., there would be no limit on swordfish retained. Regulations prohibiting the use of shallow[hyphen]set..., those regulations prohibit vessels based on the West Coast from using longline gear to make shallow sets...

Teapots with a Twist

ERIC Educational Resources Information Center

Skophammer, Karen

2012-01-01

The earliest teapots are known for their fine clay texture and thin walls. They were made from purple clay that had a natural color anywhere from light buff to deep maroon once fired. In the 1970s, novelty teapots were being made, with the vessels resembling animals and people. In these humorous designs, the tea was poured from the animals' noses…

33 CFR Schedule I to Subpart A of... - Vessels Transiting U.S. Waters

Code of Federal Regulations, 2011 CFR

2011-07-01

... required to alter the course 90 degrees with maximum rudder angle and constant power settings: (2) The time...: (A) Calm weather—wind 10 knots or less, calm sea; (B) No current; (C) Deep water conditions—water... any of the following conditions, on which the maneuvering is based, are varied: (a) Calm weather—wind...

33 CFR Schedule I to Subpart A of... - Vessels Transiting U.S. Waters

Code of Federal Regulations, 2010 CFR

2010-07-01

... required to alter the course 90 degrees with maximum rudder angle and constant power settings: (2) The time...: (A) Calm weather—wind 10 knots or less, calm sea; (B) No current; (C) Deep water conditions—water... any of the following conditions, on which the maneuvering is based, are varied: (a) Calm weather—wind...

Blood vessels segmentation of hatching eggs based on fully convolutional networks

NASA Astrophysics Data System (ADS)

Geng, Lei; Qiu, Ling; Wu, Jun; Xiao, Zhitao

2018-04-01

FCN, trained end-to-end, pixels-to-pixels, predict result of each pixel. It has been widely used for semantic segmentation. In order to realize the blood vessels segmentation of hatching eggs, a method based on FCN is proposed in this paper. The training datasets are composed of patches extracted from very few images to augment data. The network combines with lower layer and deconvolution to enables precise segmentation. The proposed method frees from the problem that training deep networks need large scale samples. Experimental results on hatching eggs demonstrate that this method can yield more accurate segmentation outputs than previous researches. It provides a convenient reference for fertility detection subsequently.

[Massive iatrogenic haemothorax treated by lidocaïne-adrenaline intercostal injection].

PubMed

Bazarbachi, T; Ghantous, W; Daher, M; Smayra, T; Riachy, M; Chelala, D; Tabet, G

2009-11-01

Massive haemothorax is a relatively rare complication of thoracocentesis or the placement of tube thoracostomy. It is principally caused by intercostal vessel injury. The therapeutic approach consists in pleural drainage and sometimes thoracotomy for haemostasis. We describe a frail 72 year old patient, who developed a massive haemothorax occurring after a tube thoracostomy placing, persisting despite second pleural drainage, and complicated by deep haemodynamic shock. He was considered to have a very high risk of mortality if surgery was undertaken. Haemorrhage was totally stopped after intercostal instillation of lidocaïne-adrenaline. This case report suggests a role for pleural vasoconstrictor injection as initial treatment in case of persistent pleural haemorrhage caused by intercostal vessel injury.

Orion and SLS showcased at Michoud on This Week @NASA – January 29, 2016

NASA Image and Video Library

2016-01-29

A Jan. 26 event at NASA’s Michoud Assembly Facility in New Orleans, marked recently completed work by technicians there to weld together the pressure vessel for the next Orion deep space crew module. The event also was an opportunity for NASA officials to thank employees and to show the progress on Orion and the core stage of the agency’s Space Launch System (SLS) rocket. The Orion pressure vessel will be shipped to Kennedy Space Center in Florida next month, where engineers will continue to prepare it for the first flight of the SLS rocket. Also, Space station One-year crew update, New color movie of Ceres and NASA Day of Remembrance!

Anatomy and histology of apical support: a literature review concerning cardinal and uterosacral ligaments.

PubMed

Ramanah, Rajeev; Berger, Mitchell B; Parratte, Bernard M; DeLancey, John O L

2012-11-01

The objective of this work was to collect and summarize relevant literature on the anatomy, histology, and imaging of apical support of the upper vagina and the uterus provided by the cardinal (CL) and uterosacral (USL) ligaments. A literature search in English, French, and German languages was carried out with the keywords apical support, cardinal ligament, transverse cervical ligament, Mackenrodt ligament, parametrium, paracervix, retinaculum uteri, web, uterosacral ligament, and sacrouterine ligament in the PubMed database. Other relevant journal and textbook articles were sought by retrieving references cited in previous PubMed articles. Fifty references were examined in peer-reviewed journals and textbooks. The USL extends from the S2 to the S4 vertebra region to the dorsal margin of the uterine cervix and/or to the upper third of the posterior vaginal wall. It has a superficial and deep component. Autonomous nerve fibers are a major constituent of the deep USL. CL is defined as a perivascular sheath with a proximal insertion around the origin of the internal iliac artery and a distal insertion on the cervix and/or vagina. It is divided into a cranial (vascular) and a caudal (neural) portions. Histologically, it contains mainly vessels, with no distinct band of connective tissue. Both the deep USL and the caudal CL are closely related to the inferior hypogastric plexus. USL and CL are visceral ligaments, with mesentery-like structures containing vessels, nerves, connective tissue, and adipose tissue.

Medical Engineering and Microneurosurgery: Application and Future.

PubMed

Morita, Akio; Sora, Shigeo; Nakatomi, Hirofumi; Harada, Kanako; Sugita, Naohiko; Saito, Nobuhito; Mitsuishi, Mamoru

2016-10-15

Robotics and medical engineering can convert traditional surgery into digital and scientific procedures. Here, we describe our work to develop microsurgical robotic systems and apply engineering technology to assess microsurgical skills. With the collaboration of neurosurgeons and an engineering team, we have developed two types of microsurgical robotic systems. The first, the deep surgical systems, enable delicate surgical procedures such as vessel suturing in a deep and narrow space. The second type allows for super-fine surgical procedures such as anastomosing artificial vessels of 0.3 mm in diameter. Both systems are constructed with master and slave manipulator robots connected to local area networks. Robotic systems allowed for secure and accurate procedures in a deep surgical field. In cadaveric models, these systems showed a good potential of being useful in actual human surgeries, but mechanical refinements in thickness and durability are necessary for them to be established as clinical systems. The super-fine robotic system made the very intricate surgery possible and will be applied in clinical trials. Another trial included the digitization of surgical technique and scientific analysis of surgical skills. Robotic and human hand motions were analyzed in numerical fashion as we tried to define surgical skillfulness in a digital format. Engineered skill assessment is also feasible and should be useful for microsurgical training. Robotics and medical engineering should bring science into the surgical field and training of surgeons. Active collaboration between medical and engineering teams and academic and industry groups is mandatory to establish such medical systems to improve patient care.

Medical Engineering and Microneurosurgery: Application and Future

PubMed Central

MORITA, Akio; SORA, Shigeo; NAKATOMI, Hirofumi; HARADA, Kanako; SUGITA, Naohiko; SAITO, Nobuhito; MITSUISHI, Mamoru

2016-01-01

Robotics and medical engineering can convert traditional surgery into digital and scientific procedures. Here, we describe our work to develop microsurgical robotic systems and apply engineering technology to assess microsurgical skills. With the collaboration of neurosurgeons and an engineering team, we have developed two types of microsurgical robotic systems. The first, the deep surgical systems, enable delicate surgical procedures such as vessel suturing in a deep and narrow space. The second type allows for super-fine surgical procedures such as anastomosing artificial vessels of 0.3 mm in diameter. Both systems are constructed with master and slave manipulator robots connected to local area networks. Robotic systems allowed for secure and accurate procedures in a deep surgical field. In cadaveric models, these systems showed a good potential of being useful in actual human surgeries, but mechanical refinements in thickness and durability are necessary for them to be established as clinical systems. The super-fine robotic system made the very intricate surgery possible and will be applied in clinical trials. Another trial included the digitization of surgical technique and scientific analysis of surgical skills. Robotic and human hand motions were analyzed in numerical fashion as we tried to define surgical skillfulness in a digital format. Engineered skill assessment is also feasible and should be useful for microsurgical training. Robotics and medical engineering should bring science into the surgical field and training of surgeons. Active collaboration between medical and engineering teams and academic and industry groups is mandatory to establish such medical systems to improve patient care. PMID:27464471

Anatomy and histology of apical support: a literature review concerning cardinal and uterosacral ligaments

PubMed Central

Ramanah, Rajeev; Berger, Mitchell B.; Parratte, Bernard M.

2014-01-01

The objective of this work was to collect and summarize relevant literature on the anatomy, histology, and imaging of apical support of the upper vagina and the uterus provided by the cardinal (CL) and uterosacral (USL) ligaments. A literature search in English, French, and German languages was carried out with the keywords apical support, cardinal ligament, transverse cervical ligament, Mackenrodt ligament, parametrium, paracervix, retinaculum uteri, web, uterosacral ligament, and sacrouterine ligament in the PubMed database. Other relevant journal and textbook articles were sought by retrieving references cited in previous PubMed articles. Fifty references were examined in peer-reviewed journals and textbooks. The USL extends from the S2 to the S4 vertebra region to the dorsal margin of the uterine cervix and/or to the upper third of the posterior vaginal wall. It has a superficial and deep component. Autonomous nerve fibers are a major constituent of the deep USL. CL is defined as a perivascular sheath with a proximal insertion around the origin of the internal iliac artery and a distal insertion on the cervix and/or vagina. It is divided into a cranial (vascular) and a caudal (neural) portions. Histologically, it contains mainly vessels, with no distinct band of connective tissue. Both the deep USL and the caudal CL are closely related to the inferior hypogastric plexus. USL and CL are visceral ligaments, with mesentery-like structures containing vessels, nerves, connective tissue, and adipose tissue. PMID:22618209

Prevention of Fat Embolism in Fat Injection for Gluteal Augmentation, Anatomic Study in Fresh Cadavers.

PubMed

Ramos-Gallardo, Guillermo; Orozco-Rentería, David; Medina-Zamora, Pablo; Mota-Fonseca, Eduardo; García-Benavides, Leonel; Cuenca-Pardo, Jesus; Contreras-Bulnes, Livia; Ambriz-Plasencia, Ana Rosa; Curiel-Beltran, Jesus Aaron

2017-05-09

Liposuction is a popular surgical procedure. As in any surgery, there are risks and complications, especially when combined with fat injection. Case reports of fat embolism have described a possible explanation as the puncture and tear of gluteal vessels during the procedure, especially when a deep injection is planned. A total of 10 dissections were performed in five fresh cadavers. Each buttocks was divided into four quadrants. We focused on the location where the gluteal vessels enter the muscle and the diameter of the vessels. Colorant at two different angles was injected (30° and 45°). We evaluated the relation of the colorant with the main vessels. We found two perforators per quadrant. The thickness of the gluteal muscle was 2.84 ± 1.54 cm. The area under the muscle where the superior gluteal vessels traverse the muscle was located 6.4 ± 1.54 cm from the intergluteal crease and 5.8 ± 1.13 cm from the superior border of the muscle. The inferior gluteal vessels were located 8.3 ± 1.39 cm from the intergluteal crease and 10 ± 2.24 cm from the superior border of the muscle. When we compared the fat injected at a 30° angle, the colorant stayed in the muscle. Using a 45° angle, the colorant was in contact with the superior gluteal artery and the sciatic nerve. No puncture or tear was observed in the vessels or the nerve. The location where the vessels come in contact with the muscle, which can be considered for fat injection, were located in quadrants 1 and 3. A 30° angle allows for an injection into the muscle without passing into deeper structures, unlike a 45° injection angle.

Observations of open-ocean deep convection in the northwestern Mediterranean Sea: Seasonal and interannual variability of mixing and deep water masses for the 2007-2013 Period

NASA Astrophysics Data System (ADS)

Houpert, L.; Durrieu de Madron, X.; Testor, P.; Bosse, A.; D'Ortenzio, F.; Bouin, M. N.; Dausse, D.; Le Goff, H.; Kunesch, S.; Labaste, M.; Coppola, L.; Mortier, L.; Raimbault, P.

2016-11-01

We present here a unique oceanographic and meteorological data set focus on the deep convection processes. Our results are essentially based on in situ data (mooring, research vessel, glider, and profiling float) collected from a multiplatform and integrated monitoring system (MOOSE: Mediterranean Ocean Observing System on Environment), which monitored continuously the northwestern Mediterranean Sea since 2007, and in particular high-frequency potential temperature, salinity, and current measurements from the mooring LION located within the convection region. From 2009 to 2013, the mixed layer depth reaches the seabed, at a depth of 2330m, in February. Then, the violent vertical mixing of the whole water column lasts between 9 and 12 days setting up the characteristics of the newly formed deep water. Each deep convection winter formed a new warmer and saltier "vintage" of deep water. These sudden inputs of salt and heat in the deep ocean are responsible for trends in salinity (3.3 ± 0.2 × 10-3/yr) and potential temperature (3.2 ± 0.5 × 10-3 C/yr) observed from 2009 to 2013 for the 600-2300 m layer. For the first time, the overlapping of the three "phases" of deep convection can be observed, with secondary vertical mixing events (2-4 days) after the beginning of the restratification phase, and the restratification/spreading phase still active at the beginning of the following deep convection event.

Safely Combining Abdominoplasty with Aggressive Abdominal Liposuction Based on Perforator Vessels: Technique and a Review of 300 Consecutive Cases

PubMed Central

Smith, Lane F.

2015-01-01

Background: There continues to be controversy about performing abdominoplasty concurrently with abdominal liposuction. The concern is that liposuction on the already vascularly compromised abdominal flap will lead to increased complications and flap necrosis. The central abdomen is supplied by the epigastric system. If perforator vessels from this system are spared, the blood supply to the abdomen can be spared and liposuction should be able to be safely performed on the elevated abdominal flap. The purpose of this study was to evaluate the safety of abdominoplasty with concurrent abdominal liposuction when a perforator vessel is spared. Methods: A standard abdominoplasty was performed, sparing one or two perforator vessels from the deep superior epigastric artery system. A retrospective chart review of 300 consecutive patients who underwent abdominoplasty surgery combined with concurrent abdominal liposuction was performed. Complications, total volume of abdominal liposuction, and results were reviewed. Results: The overall complication rate was 17.3 percent (52 patients). Sixteen percent (48 patients) suffered minor complications and 1.3 percent (four patients) suffered major complications. Conclusions: Abdominoplasty can be combined safely with concurrent abdominal liposuction when a perforator vessel is spared. The combination of concurrent liposuction with abdominoplasty showed no increase in complication rates when a perforator vessel was spared. The perforator vessels are located consistently in a 2-cm radius located 4 cm from the midline and 6 cm from the subcostal margin. The potential advantages of abdominoplasty with concurrent liposuction include a better postoperative cosmetic result. CLINICAL QUESTION/LEVEL OF EVIDENCE: Therapeutic, IV. PMID:25919250

Extracellular matrix inflammation in vascular cognitive impairment and dementia.

PubMed

Rosenberg, Gary A

2017-03-01

Vascular cognitive impairment and dementia (VCID) include a wide spectrum of chronic manifestations of vascular disease related to large vessel strokes and small vessel disease (SVD). Lacunar strokes and white matter (WM) injury are consequences of SVD. The main vascular risk factor for SVD is brain hypoperfusion from cerebral blood vessel narrowing due to chronic hypertension. The hypoperfusion leads to activation and degeneration of astrocytes with the resulting fibrosis of the extracellular matrix (ECM). Elasticity is lost in fibrotic cerebral vessels, reducing the response of stiffened blood vessels in times of increased metabolic need. Intermittent hypoxia/ischaemia activates a molecular injury cascade, producing an incomplete infarction that is most damaging to the deep WM, which is a watershed region for cerebral blood flow. Neuroinflammation caused by hypoxia activates microglia/macrophages to release proteases and free radicals that perpetuate the damage over time to molecules in the ECM and the neurovascular unit (NVU). Matrix metalloproteinases (MMPs) secreted in an attempt to remodel the blood vessel wall have the undesired consequences of opening the blood-brain barrier (BBB) and attacking myelinated fibres. This dual effect of the MMPs causes vasogenic oedema in WM and vascular demyelination, which are the hallmarks of the subcortical ischaemic vascular disease (SIVD), which is the SVD form of VCID also called Binswanger's disease (BD). Unravelling the complex pathophysiology of the WM injury-related inflammation in the small vessel form of VCID could lead to novel therapeutic strategies to reduce damage to the ECM, preventing the progressive damage to the WM. © 2017 The Author(s). published by Portland Press Limited on behalf of the Biochemical Society.

76 FR 58455 - Fisheries of the Caribbean, Gulf of Mexico, and South Atlantic; Reef Fish Fishery of the Gulf of...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-21

... for shallow- water grouper (SWG), set the commercial quota for red grouper and SWG from 2012 to 2015... update indicated that the stock continues to be neither overfished nor undergoing overfishing. However... landings of deep-water grouper species. On average, in 2010, these vessels received an initial allocation...

The role of invasive trophoblast in implantation and placentation of primates

PubMed Central

Carter, Anthony M.; Enders, Allen C.; Pijnenborg, Robert

2015-01-01

We here review the evolution of invasive placentation in primates towards the deep penetration of the endometrium and its arteries in hominoids. The strepsirrhine primates (lemurs and lorises) have non-invasive, epitheliochorial placentation, although this is thought to be derived from a more invasive type. In haplorhine primates, there is differentiation of trophoblast at the blastocyst stage into syncytial and cellular trophoblast. Implantation involves syncytiotrophoblast that first removes the uterine epithelium then consolidates at the basal lamina before continuing into the stroma. In later stages of pregnancy, especially in Old World monkeys and apes, cytotrophoblast plays a greater role in the invasive process. Columns of trophoblast cells advance to the base of the implantation site where they spread out to form a cytotrophoblastic shell. In addition, cytotrophoblasts advance into the lumen of the spiral arteries. They are responsible for remodelling these vessels to form wide, low-resistance conduits. In human and great apes, there is additional invasion of the endometrium and its vessels by trophoblasts originating from the base of the anchoring villi. Deep trophoblast invasion that extends remodelling of the spiral arteries to segments in the inner myometrium evolved in the common ancestor of gorilla, chimp and human. PMID:25602074

Body surface detection method for photoacoustic image data using cloth-simulation technique

NASA Astrophysics Data System (ADS)

Sekiguchi, H.; Yoshikawa, A.; Matsumoto, Y.; Asao, Y.; Yagi, T.; Togashi, K.; Toi, M.

2018-02-01

Photoacoustic tomography (PAT) is a novel modality that can visualize blood vessels without contrast agents. It clearly shows blood vessels near the body surface. However, these vessels obstruct the observation of deep blood vessels. As the existence range of each vessel is determined by the distance from the body surface, they can be separated if the position of the skin is known. However, skin tissue, which does not contain hemoglobin, does not appear in PAT results, therefore, manual estimation is required. As this task is very labor-intensive, its automation is highly desirable. Therefore, we developed a method to estimate the body surface using the cloth-simulation technique, which is a commonly used method to create computer graphics (CG) animations; however, it has not yet been employed for medical image processing. In cloth simulations, the virtual cloth is represented by a two-dimensional array of mass nodes. The nodes are connected with each other by springs. Once the cloth is released from a position away from the body, each node begins to move downwards under the effect of gravity, spring, and other forces; some of the nodes hit the superficial vessels and stop. The cloth position in the stationary state represents the body surface. The body surface estimation, which required approximately 1 h with the manual method, is automated and it takes only approximately 10 s with the proposed method. The proposed method could facilitate the practical use of PAT.

Deep magnetic capture of magnetically loaded cells for spatially targeted therapeutics.

PubMed

Huang, Zheyong; Pei, Ning; Wang, Yanyan; Xie, Xinxing; Sun, Aijun; Shen, Li; Zhang, Shuning; Liu, Xuebo; Zou, Yunzeng; Qian, Juying; Ge, Junbo

2010-03-01

Magnetic targeting has recently demonstrated potential in promoting magnetically loaded cell delivery to target lesion, but its application is limited by magnetic attenuation. For deep magnetic capture of cells for spatial targeting therapeutics, we designed a magnetic pole, in which the magnetic field density can be focused at a distance from the pole. As flowing through a tube served as a model of blood vessels, the magnetically loaded mesenchymal stem cells (MagMSCs) were highly enriched at the site distance from the magnetic pole. The cell capture efficiency was positively influenced by the magnetic flux density, and inversely influenced by the flow velocity, and well-fitted with the deductive value by theoretical considerations. It appeared to us that the spatially-focused property of the magnetic apparatus promises a new deep targeting strategy to promote homing and engraftment for cellular therapy. Copyright (c) 2009 Elsevier Ltd. All rights reserved.

Deep neural ensemble for retinal vessel segmentation in fundus images towards achieving label-free angiography.

PubMed

Lahiri, A; Roy, Abhijit Guha; Sheet, Debdoot; Biswas, Prabir Kumar

2016-08-01

Automated segmentation of retinal blood vessels in label-free fundus images entails a pivotal role in computed aided diagnosis of ophthalmic pathologies, viz., diabetic retinopathy, hypertensive disorders and cardiovascular diseases. The challenge remains active in medical image analysis research due to varied distribution of blood vessels, which manifest variations in their dimensions of physical appearance against a noisy background. In this paper we formulate the segmentation challenge as a classification task. Specifically, we employ unsupervised hierarchical feature learning using ensemble of two level of sparsely trained denoised stacked autoencoder. First level training with bootstrap samples ensures decoupling and second level ensemble formed by different network architectures ensures architectural revision. We show that ensemble training of auto-encoders fosters diversity in learning dictionary of visual kernels for vessel segmentation. SoftMax classifier is used for fine tuning each member autoencoder and multiple strategies are explored for 2-level fusion of ensemble members. On DRIVE dataset, we achieve maximum average accuracy of 95.33% with an impressively low standard deviation of 0.003 and Kappa agreement coefficient of 0.708. Comparison with other major algorithms substantiates the high efficacy of our model.

A dural lymphatic vascular system that drains brain interstitial fluid and macromolecules

PubMed Central

Aspelund, Aleksanteri; Antila, Salli; Proulx, Steven T.; Karlsen, Tine Veronica; Karaman, Sinem; Detmar, Michael; Wiig, Helge

2015-01-01

The central nervous system (CNS) is considered an organ devoid of lymphatic vasculature. Yet, part of the cerebrospinal fluid (CSF) drains into the cervical lymph nodes (LNs). The mechanism of CSF entry into the LNs has been unclear. Here we report the surprising finding of a lymphatic vessel network in the dura mater of the mouse brain. We show that dural lymphatic vessels absorb CSF from the adjacent subarachnoid space and brain interstitial fluid (ISF) via the glymphatic system. Dural lymphatic vessels transport fluid into deep cervical LNs (dcLNs) via foramina at the base of the skull. In a transgenic mouse model expressing a VEGF-C/D trap and displaying complete aplasia of the dural lymphatic vessels, macromolecule clearance from the brain was attenuated and transport from the subarachnoid space into dcLNs was abrogated. Surprisingly, brain ISF pressure and water content were unaffected. Overall, these findings indicate that the mechanism of CSF flow into the dcLNs is directly via an adjacent dural lymphatic network, which may be important for the clearance of macromolecules from the brain. Importantly, these results call for a reexamination of the role of the lymphatic system in CNS physiology and disease. PMID:26077718

A dural lymphatic vascular system that drains brain interstitial fluid and macromolecules.

PubMed

Aspelund, Aleksanteri; Antila, Salli; Proulx, Steven T; Karlsen, Tine Veronica; Karaman, Sinem; Detmar, Michael; Wiig, Helge; Alitalo, Kari

2015-06-29

The central nervous system (CNS) is considered an organ devoid of lymphatic vasculature. Yet, part of the cerebrospinal fluid (CSF) drains into the cervical lymph nodes (LNs). The mechanism of CSF entry into the LNs has been unclear. Here we report the surprising finding of a lymphatic vessel network in the dura mater of the mouse brain. We show that dural lymphatic vessels absorb CSF from the adjacent subarachnoid space and brain interstitial fluid (ISF) via the glymphatic system. Dural lymphatic vessels transport fluid into deep cervical LNs (dcLNs) via foramina at the base of the skull. In a transgenic mouse model expressing a VEGF-C/D trap and displaying complete aplasia of the dural lymphatic vessels, macromolecule clearance from the brain was attenuated and transport from the subarachnoid space into dcLNs was abrogated. Surprisingly, brain ISF pressure and water content were unaffected. Overall, these findings indicate that the mechanism of CSF flow into the dcLNs is directly via an adjacent dural lymphatic network, which may be important for the clearance of macromolecules from the brain. Importantly, these results call for a reexamination of the role of the lymphatic system in CNS physiology and disease. © 2015 Aspelund et al.

Deep-Sea Coral Image Catalog: Northeast Pacific

NASA Astrophysics Data System (ADS)

Freed, J. C.

2016-02-01

In recent years, deep-sea exploration in the Northeast Pacific ocean has been on the rise using submersibles and remotely operated vehicles (ROVs), acquiring a plethora of underwater videos and photographs. Analysis of deep-sea fauna revealed by this research has been hampered by the lack of catalogs or guides that allow identification of species in the field. Deep-sea corals are of particular conservation concern, but currently, there are few catalogs which describe and provide detailed information on deep-sea corals from the Northeast Pacific and those that exist are focused on small, specific areas. This project, in collaboration with NOAA's Deep-Sea Coral Ecology Laboratory at the Center for Coastal Environmental Health and Biomolecular Research (CCEHBR) and the Southwest Fisheries Science Center (SWFSC), developed pages for a deep-sea coral identification guide that provides photos and information on the visual identification, distributions, and habitats of species found in the Northeast Pacific. Using online databases, photo galleries, and literature, this catalog has been developed to be a living document open to future additions. This project produced 12 entries for the catalog on a variety of different deep-sea corals. The catalog is intended to be used during underwater surveys in the Northeast Pacific, but will also assist in identification of deep-sea coral by-catch by fishing vessels, and for general educational use. These uses will advance NOAA's ability to identify and protect sensitive deep-sea habitats that act as biological hotspots. The catalog is intended to be further developed into an online resource with greater interactive features with links to other resources and featured on NOAA's Deep-Sea Coral Data Portal.

Use of unmanned aerial vehicles for medical product transport.

PubMed

Thiels, Cornelius A; Aho, Johnathon M; Zietlow, Scott P; Jenkins, Donald H

2015-01-01

Advances in technology and decreasing costs have led to an increased use of unmanned aerial vehicles (UAVs) by the military and civilian sectors. The use of UAVs in commerce is restricted by US Federal Aviation Administration (FAA) regulations, but the FAA is drafting new regulations that are expected to expand commercial applications. Currently, the transportation of medical goods in times of critical need is limited to wheeled motor vehicles and manned aircraft, options that can be costly and slow. This article explores the demand for, feasibility of, and risks associated with the use of UAVs to deliver medical products, including blood derivatives and pharmaceuticals, to hospitals, mass casualty scenes, and offshore vessels in times of critical demand. Copyright © 2015 Air Medical Journal Associates. Published by Elsevier Inc. All rights reserved.

Deep intubation of 8 Fr guiding catheter to deliver coronary stent graft to seal coronary perforation: a case report.

PubMed

Salwan, R; Mathur, A; Jhamb, D K; Seth, A

2001-09-01

Coronary perforation is an uncommon complication of angioplasty and is a challenging situation to manage. We describe a case of complex multivessel coronary angioplasty complicated by coronary perforation following balloon rupture that was successfully managed with a coronary stent graft. Delivery of the stent graft to the site of vessel rupture required deep intubation of an 8 Fr guiding catheter over the shaft of an inflated balloon. In addition to the availability of covered stents, it is essential to be familiar with various skills necessary to deploy these stents. Cathet Cardiovasc Intervent 2001;54:59-62. Copyright 2001 Wiley-Liss, Inc.

Summary of JPL Activities

NASA Technical Reports Server (NTRS)

Timmerman, Paul J.; Surampudi, Subbarao

2000-01-01

A viewgraph presentation outlines the Jet Propulsion Laboratory (JPL) flight programs, including past, present and future missions targeting Solar System exploration. Details, including launch dates and batteries used, are given for Deep Space 1 (Asteroid Rendezvous), Deep Space 2 (Mars Penetrator), Mars Global Surveyor, Mars Surveyor '98, Stardust, Europa Orbiter, Mars Surveyor 2001, Mars 2003 Lander and Rover, and Genesis (Solar Dust Return). Earth science projects are also outlined: Active Cavity Radiometer Irradiance Monitor (ARIMSAT), Ocean Topography Experiment (TOPEX/Poseidon), Jason-1 (TOPEX follow-on), and QuikScat/Seawinds (Ocean Winds Tracking). The status, background, and plans are given for several batteries: (1) 2.5 inch common pressure vessel (CPV), (2) 3.5 inch CPV, (3) Ni-H2, and (4) Li-Ion.

Detailed investigation of the microbial community in foaming activated sludge reveals novel foam formers

PubMed Central

Guo, Feng; Wang, Zhi-Ping; Yu, Ke; Zhang, T.

2015-01-01

Foaming of activated sludge (AS) causes adverse impacts on wastewater treatment operation and hygiene. In this study, we investigated the microbial communities of foam, foaming AS and non-foaming AS in a sewage treatment plant via deep-sequencing of the taxonomic marker genes 16S rRNA and mycobacterial rpoB and a metagenomic approach. In addition to Actinobacteria, many genera (e.g., Clostridium XI, Arcobacter, Flavobacterium) were more abundant in the foam than in the AS. On the other hand, deep-sequencing of rpoB did not detect any obligate pathogenic mycobacteria in the foam. We found that unknown factors other than the abundance of Gordonia sp. could determine the foaming process, because abundance of the same species was stable before and after a foaming event over six months. More interestingly, although the dominant Gordonia foam former was the closest with G. amarae, it was identified as an undescribed Gordonia species by referring to the 16S rRNA gene, gyrB and, most convincingly, the reconstructed draft genome from metagenomic reads. Our results, based on metagenomics and deep sequencing, reveal that foams are derived from diverse taxa, which expands previous understanding and provides new insight into the underlying complications of the foaming phenomenon in AS. PMID:25560234

The lymphatic mechanisms of brain cleaning: application of optical coherence tomography and fluorescence microscopy

NASA Astrophysics Data System (ADS)

Glushkovskaya-Semyachkina, O.; Abdurashitov, A.; Fedosov, I.; Namykin, A.; Pavlov, A.; Shirokov, A.; Shushunova, N.; Sindeeva, O.; Khorovodov, A.; Ulanova, M.; Sagatova, V.; Agranovich, I.; Bodrova, A.; Kurths, J.

2018-04-01

Here we studied the role of cerebral lymphatic system in the brain clearing using intraparenchymal injection of Evans Blue and gold nanorods assessed by optical coherent tomography and fluorescence microscopy. Our data clearly show that the cerebral lymphatic system plays an important role in the brain cleaning via meningeal lymphatic vessels but not cerebral veins. Meningeal lymphatic vessels transport fluid from the brain into the deep cervical node, which is the first anatomical "station" for lymph outflow from the brain. The lymphatic processes underlying brain clearing are more slowly vs. peripheral lymphatics. These results shed light on the lymphatic mechanisms responsible for brain clearing as well as interaction between the intra- and extracranial lymphatic compartment.

A novel high-pressure vessel for simultaneous observations of seismic velocity and in situ CO2 distribution in a porous rock using a medical X-ray CT scanner

NASA Astrophysics Data System (ADS)

Jiang, Lanlan; Nishizawa, Osamu; Zhang, Yi; Park, Hyuck; Xue, Ziqiu

2016-12-01

Understanding the relationship between seismic wave velocity or attenuation and CO2 saturation is essential for CO2 storage in deep saline formations. In the present study, we describe a novel upright high-pressure vessel that is designed to keep a rock sample under reservoir conditions and simultaneously image the entire sample using a medical X-ray CT scanner. The pressure vessel is composed of low X-ray absorption materials: a carbon-fibre-enhanced polyetheretherketone (PEEK) cylinder and PEEK vessel closures supported by carbon-fibre-reinforced plastic (CFRP) joists. The temperature was controlled by a carbon-coated film heater and an aramid fibre thermal insulator. The assembled sample cell allows us to obtain high-resolution images of rock samples during CO2 drainage and brine imbibition under reservoir conditions. The rock sample was oriented vertical to the rotation axis of the CT scanner, and seismic wave paths were aligned parallel to the rotation axis to avoid shadows from the acoustic transducers. The reconstructed CO2 distribution images allow us to calculate the CO2 saturation in the first Fresnel zone along the ray path between transducers. A robust relationship between the seismic wave velocity or attenuation and the CO2 saturation in porous rock was obtained from experiments using this pressure vessel.

46 CFR 32.50-20 - Cargo piping for tank vessels constructed between November 10, 1936, and July 1, 1951-TB/ALL.

Code of Federal Regulations, 2011 CFR

2011-10-01

... provide for expansion and contraction. (b) Cargo piping shall not pass through spaces containing machinery... be carried through bunker spaces and deep tanks provided it is run through a pipe tunnel. The tunnel... permit the piping to pass through such spaces if Grade E liquids only are involved. (c) Valve operating...

46 CFR 32.50-20 - Cargo piping for tank vessels constructed between November 10, 1936, and July 1, 1951-TB/ALL.

Code of Federal Regulations, 2013 CFR

2013-10-01

... provide for expansion and contraction. (b) Cargo piping shall not pass through spaces containing machinery... be carried through bunker spaces and deep tanks provided it is run through a pipe tunnel. The tunnel... permit the piping to pass through such spaces if Grade E liquids only are involved. (c) Valve operating...

46 CFR 32.50-20 - Cargo piping for tank vessels constructed between November 10, 1936, and July 1, 1951-TB/ALL.

Code of Federal Regulations, 2014 CFR

2014-10-01

... provide for expansion and contraction. (b) Cargo piping shall not pass through spaces containing machinery... be carried through bunker spaces and deep tanks provided it is run through a pipe tunnel. The tunnel... permit the piping to pass through such spaces if Grade E liquids only are involved. (c) Valve operating...

46 CFR 32.50-20 - Cargo piping for tank vessels constructed between November 10, 1936, and July 1, 1951-TB/ALL.

Code of Federal Regulations, 2012 CFR

2012-10-01

... provide for expansion and contraction. (b) Cargo piping shall not pass through spaces containing machinery... be carried through bunker spaces and deep tanks provided it is run through a pipe tunnel. The tunnel... permit the piping to pass through such spaces if Grade E liquids only are involved. (c) Valve operating...

46 CFR 32.50-20 - Cargo piping for tank vessels constructed between November 10, 1936, and July 1, 1951-TB/ALL.

Code of Federal Regulations, 2010 CFR

2010-10-01

... provide for expansion and contraction. (b) Cargo piping shall not pass through spaces containing machinery... be carried through bunker spaces and deep tanks provided it is run through a pipe tunnel. The tunnel... permit the piping to pass through such spaces if Grade E liquids only are involved. (c) Valve operating...

United States Coast Guard Fiscal Year 2009 Performance Report

DTIC Science & Technology

2010-02-01

flooding. The International Ice Patrol facilitates interna- tional commerce by broadcasting information on iceberg locations to vessels transiting...SEA also provided back-up capability for the U.S. Antarctic Deep Freeze resupply mission. • The United States Coast Guard International Ice Patrol...tracked over 1,200 icebergs which drifted into the transatlantic shipping lanes continuing its perfect record, 96 years, of preventing ship collisions

Species Profiles: Life Histories and Environmental Requirements of Coastal Vertebrates and Invertebrates Pacific Ocean Region. Report 4. The Hawaiian Anchovy or Nehu Encrasicholina purpurea (Engraulidae)

DTIC Science & Technology

1989-11-01

including tilapia , threadfin shad, vessel is anchored in deep water-- and top minnows, have been tested usually close to reef areas--and a and either...T. A. In press. Seasonal use of tilapia as live bait. differences in spawning, egg size, Terr. of Hawaii, Industrial and early development of the

AURORA BOREALIS - Development of a New Research Icebreaker with Drilling Capability

NASA Astrophysics Data System (ADS)

Thiede, J.; Biebow, N.; Egerton, P.; Kunz-Pirrung, M.; Lembke-Jene, L.

2007-12-01

Polar research both on land and in the sea cannot achieve the needed progress without novel and state of the art technologies and infrastructure. In addition, we have the obligation to equip the upcoming young and courageous generation of polar researchers with the most modern and safest research platforms the 21st century can provide. This effort will require major investments, both in terms of generating new tools, as well as maintaining and renovating existing infrastructure. There are many different novel tools under development for polar research, we will concentrate on the presently largest one, the planning for a new type of research icebreaker, the AURORA BOREALIS with an all-season capability of operations in permanently ice-covered waters and with the possibility to carry out deep-sea drilling in ice-covered deep-sea basins. AURORA BOREALIS will be the most advanced Polar Research Vessel in the world with a multi-functional role of drilling in deep ocean basins and supporting climate and environmental research and decision support for stakeholder governments for the next 35 to 40 years. The vessel is planned as a large research icebreaker with 44,000 tons displacement and a length of up to 196 m, with about 50 Megawatt propulsion power. Advanced technological features will include azimuth propulsion systems, extensive instrumental and airborne ice- management support, and the routine operation of Remotely Operated Vehicles (ROV) and Autonomous Underwater Vehicles (AUVs) from two moon-pools. An unique feature of this icebreaker will be the drilling rig that will enable sampling of the ocean floor and sub-sea down to 5000 m water depth and 1000 m penetration at the most inhospitable places on earth. The possibility to flexibly equip the ship with laboratory and supply containers, and the variable arrangement of other modular infrastructure (in particular, winches, cranes, etc.), free deck- space, and separate protected deck areas, will allow the planned research vessel to cover the needs of most disciplines in marine research. aurora-borealis.eu/en/about_aurora_borealis/

Optical Coherence Tomography Angiography of Retinal Microvascular Changes Overlying Choroidal Nodules in Neurofibromatosis Type 1

PubMed Central

Cassiman, Catherine; Casteels, Ingele; Stalmans, Peter; Legius, Eric; Jacob, Julie

2017-01-01

Purpose To report 3 cases of neurofibromatosis type 1 (NF1) with choroidal nodules associated with retinal microvascular changes imaged with optical coherence tomography angiography (OCTA). Methods Small case series in 3 NF1 patients. OCTA examinations were performed by a trained examiner (J.J.) after pupillary dilation. A standard scan, centered over the macula measuring 6 × 6 mm and 3 × 3 mm was obtained according to the findings on standard color photography. Additional scans were obtained in the zones with microvascular abnormalities. The segmentation provided by the machine software was used. Results Corkscrew retinal vessels were observed in association with “placoid”-type choroidal nodules as shown by near-infrared reflectance imaging. In all cases, multiple lesions were found. They were second- or third-order tortuous vessels originating from the superior or inferior temporal veins. OCTA demonstrated that the tortuous venules were located in the superficial capillary plexus, and no abnormalities were found in the deep capillary plexus. Discussion Corkscrew retinal vessels are part of a spectrum of retinal microvascular alterations seen in association, sometimes overlying choroidal nodules in patients with NF1 and are visualized in the superficial capillary plexus on OCTA. We demonstrated with OCTA that they are not associated with flow loss or ischemia in the superficial and deep capillary plexus. The link between the underlying nodule remains unclear. Since neovascularization was described in choroidal ganglioneuroma, we hypothesize that corresponding secretory substances from Schwann cells, ganglion cells, or melanocytes in choroidal nodules might alter the retinal vasculature. Conclusion We report on 3 cases of NF1 with choroidal nodules in association with retinal microvascular changes imaged with OCTA. OCTA demonstrated preservation of the blood flow in the deep and superficial capillary plexus of the retina. We hypothesize that angiogenic factors secreted by the underlying choroidal nodules could have an effect on the retinal vasculature. Further immunohistological studies in NF1 patients with choroidal nodules to detect angiogenic factors (such as VEGF) are necessary to confirm this hypothesis. PMID:28512424

Line-Scanning Particle Image Velocimetry: An Optical Approach for Quantifying a Wide Range of Blood Flow Speeds in Live Animals

PubMed Central

Kim, Tyson N.; Goodwill, Patrick W.; Chen, Yeni; Conolly, Steven M.; Schaffer, Chris B.; Liepmann, Dorian; Wang, Rong A.

2012-01-01

Background The ability to measure blood velocities is critical for studying vascular development, physiology, and pathology. A key challenge is to quantify a wide range of blood velocities in vessels deep within living specimens with concurrent diffraction-limited resolution imaging of vascular cells. Two-photon laser scanning microscopy (TPLSM) has shown tremendous promise in analyzing blood velocities hundreds of micrometers deep in animals with cellular resolution. However, current analysis of TPLSM-based data is limited to the lower range of blood velocities and is not adequate to study faster velocities in many normal or disease conditions. Methodology/Principal Findings We developed line-scanning particle image velocimetry (LS-PIV), which used TPLSM data to quantify peak blood velocities up to 84 mm/s in live mice harboring brain arteriovenous malformation, a disease characterized by high flow. With this method, we were able to accurately detect the elevated blood velocities and exaggerated pulsatility along the abnormal vascular network in these animals. LS-PIV robustly analyzed noisy data from vessels as deep as 850 µm below the brain surface. In addition to analyzing in vivo data, we validated the accuracy of LS-PIV up to 800 mm/s using simulations with known velocity and noise parameters. Conclusions/Significance To our knowledge, these blood velocity measurements are the fastest recorded with TPLSM. Partnered with transgenic mice carrying cell-specific fluorescent reporters, LS-PIV will also enable the direct in vivo correlation of cellular, biochemical, and hemodynamic parameters in high flow vascular development and diseases such as atherogenesis, arteriogenesis, and vascular anomalies. PMID:22761686

Role of the Norrie disease pseudoglioma gene in sprouting angiogenesis during development of the retinal vasculature.

PubMed

Luhmann, Ulrich F O; Lin, Jihong; Acar, Niyazi; Lammel, Stefanie; Feil, Silke; Grimm, Christian; Seeliger, Mathias W; Hammes, Hans-Peter; Berger, Wolfgang

2005-09-01

To characterize developmental defects and the time course of Norrie disease in retinal and hyaloid vasculature during retinal development and to identify underlying molecular angiogenic pathways that may be affected in Norrie disease, exudative vitreoretinopathy, retinopathy of prematurity, and Coats' disease. Norrie disease pseudoglioma homologue (Ndph)-knockout mice were studied during retinal development at early postnatal (p) stages (p5, p10, p15, and p21). Histologic techniques, quantitative RT-PCR, ELISA, and Western blot analyses provided molecular data, and scanning laser ophthalmoscopy (SLO) angiography and electroretinography (ERG) were used to obtain in vivo data. The data showed that regression of the hyaloid vasculature of Ndph-knockout mice occurred but was drastically delayed. The development of the superficial retinal vasculature was strongly delayed, whereas the deep retinal vasculature did not form because of the blockage of vessel outgrowth into the deep retinal layers. Subsequently, microaneurysm-like lesions formed. Several angiogenic factors were differentially transcribed during retinal development. Increased levels of hypoxia inducible factor-1alpha (HIF1alpha) and VEGFA, as well as a characteristic ERG pattern, confirmed hypoxic conditions in the inner retina of the Ndph-knockout mouse. These data provide evidence for a crucial role of Norrin in hyaloid vessel regression and in sprouting angiogenesis during retinal vascular development, especially in the development of the deep retinal capillary networks. They also suggest an early and a late phase of Norrie disease and may provide an explanation for similar phenotypic features of allelic retinal diseases in mice and patients as secondary consequences of pathologic hypoxia.

Fully automated disease severity assessment and treatment monitoring in retinopathy of prematurity using deep learning

NASA Astrophysics Data System (ADS)

Brown, James M.; Campbell, J. Peter; Beers, Andrew; Chang, Ken; Donohue, Kyra; Ostmo, Susan; Chan, R. V. Paul; Dy, Jennifer; Erdogmus, Deniz; Ioannidis, Stratis; Chiang, Michael F.; Kalpathy-Cramer, Jayashree

2018-03-01

Retinopathy of prematurity (ROP) is a disease that affects premature infants, where abnormal growth of the retinal blood vessels can lead to blindness unless treated accordingly. Infants considered at risk of severe ROP are monitored for symptoms of plus disease, characterized by arterial tortuosity and venous dilation at the posterior pole, with a standard photographic definition. Disagreement among ROP experts in diagnosing plus disease has driven the development of computer-based methods that classify images based on hand-crafted features extracted from the vasculature. However, most of these approaches are semi-automated, which are time-consuming and subject to variability. In contrast, deep learning is a fully automated approach that has shown great promise in a wide variety of domains, including medical genetics, informatics and imaging. Convolutional neural networks (CNNs) are deep networks which learn rich representations of disease features that are highly robust to variations in acquisition and image quality. In this study, we utilized a U-Net architecture to perform vessel segmentation and then a GoogLeNet to perform disease classification. The classifier was trained on 3,000 retinal images and validated on an independent test set of patients with different observed progressions and treatments. We show that our fully automated algorithm can be used to monitor the progression of plus disease over multiple patient visits with results that are consistent with the experts' consensus diagnosis. Future work will aim to further validate the method on larger cohorts of patients to assess its applicability within the clinic as a treatment monitoring tool.

Defective angiogenesis delays thrombus resolution: a potential pathogenetic mechanism underlying chronic thromboembolic pulmonary hypertension

PubMed Central

Panzenboeck, Adelheid; Winter, Max P; Schubert, Uwe; Voswinckel, Robert; Frey, Maria K; Jakowitsch, Johannes; Alimohammadi, Arman; Hobohm, Lukas; Mangold, Andreas; Bergmeister, Helga; Sibilia, Maria; Wagner, Erwin F; Mayer, Eckhard; Klepetko, Walter; Hoelzenbein, Thomas J; Preissner, Klaus T; Lang, Irene M

2015-01-01

Objective Restoration of patency is a natural target of vascular remodeling following venous thrombosis that involves vascular endothelial cells and smooth muscle cells as well as leukocytes. Acute pulmonary emboli usually resolve within six months. However, in some instances, thrombi transform into fibrous vascular obstructions, resulting in occlusion of the deep veins, or in chronic thromboembolic pulmonary hypertension (CTEPH). We proposed that dysregulated thrombus angiogenesis may contribute to thrombus persistence. Approach and Results Mice with an endothelial-cell-specific conditional deletion of vascular endothelial growth factor receptor 2/kinase insert domain protein receptor (VEGF-R2/Kdr) were utilized in a model of stagnant flow venous thrombosis closely resembling human deep vein thrombosis. Biochemical and functional analyses were performed on pulmonary endarterectomy specimens from patients with CTEPH, a human model of non-resolving venous thromboembolism. Endothelial cell-specific deletion of Kdr and subsequent ablation of thrombus vascularization delayed thrombus resolution. In accordance with these findings, organized human CTEPH thrombi were largely devoid of vascular structures. Several vessel-specific genes such as KDR, vascular endothelial cadherin and podoplanin were expressed at lower levels in white CTEPH thrombi than in organizing deep vein thrombi and organizing thrombi from aortic aneurysms. In addition, red CTEPH thrombi attenuated the angiogenic response induced by VEGF. Conclusions In the present work, we propose a mechanism of thrombus non-resolution demonstrating that endothelial cell-specific deletion of Kdr abates thrombus vessel formation, misguiding thrombus resolution. Medical conditions associated with the development of CTEPH may be compromising early thrombus angiogenesis. PMID:24526692

Photoacoustic diagnosis of burns in rats: two-dimensional photo-acoustic imaging of burned tissue

NASA Astrophysics Data System (ADS)

Yamazaki, Mutsuo; Sato, Shunichi; Saito, Daizo; Okada, Yoshiaki; Kurita, Akira; Kikuchi, Makoto; Ashida, Hiroshi; Obara, Minoru

2003-06-01

We previously reported that for rat burn models, deep dermal burns and deep burns can be well differentiated by measuring the propagation time of the photoacoustic signals originated from the blood in the healthy skin tissue under the damaged tissue layer. However, the diagnosis was based on point measurement in the wound, and therefore site-dependent information on the injuries was not obtained; such information is very important for diagnosis of extended burns. In the present study, we scanned a photoacoustic detector on the wound and constructed two-dimensional (2-D) images of the blood-originated photoacoustic signals for superficial dermal burns (SDB), deep dermal burns (DDB), deep burns (DB), and healthy skins (control) in rats. For each burn model, site-dependent variation of the signal was observed; the variation probably reflects the distribution of blood vessels in the skin tissue. In spite of the variation, clear differentiation was obtained between SDB, DDB, and DB from the 2D images. The images were constructed as a function of post burn time. Temporal signal variation will be also presented.

Detection and characterisation of deep-sea benthopelagic animals from an autonomous underwater vehicle with a multibeam echosounder: A proof of concept and description of data-processing methods

NASA Astrophysics Data System (ADS)

Dunlop, Katherine M.; Jarvis, Toby; Benoit-Bird, Kelly J.; Waluk, Chad M.; Caress, David W.; Thomas, Hans; Smith, Kenneth L.

2018-04-01

Benthopelagic animals are an important component of the deep-sea ecosystem, yet are notoriously difficult to study. Multibeam echosounders (MBES) deployed on autonomous underwater vehicles (AUVs) represent a promising technology for monitoring this elusive fauna at relatively high spatial and temporal resolution. However, application of this remote-sensing technology to the study of small (relative to the sampling resolution), dispersed and mobile animals at depth does not come without significant challenges with respect to data collection, data processing and vessel avoidance. As a proof of concept, we used data from a downward-looking RESON SeaBat 7125 MBES mounted on a Dorado-class AUV to detect and characterise the location and movement of backscattering targets (which were likely to have been individual fish or squid) within 50 m of the seafloor at 800 m depth in Monterey Bay, California. The targets were detected and tracked, enabling their numerical density and movement to be characterised. The results revealed a consistent movement of targets downwards away from the AUV that we interpreted as an avoidance response. The large volume and complexity of the data presented a computational challenge, while reverberation and noise, spatial confounding and a marginal sampling resolution relative to the size of the targets caused difficulties for reliable and comprehensive target detection and tracking. Nevertheless, the results demonstrate that an AUV-mounted MBES has the potential to provide unique and detailed information on the in situ abundance, distribution, size and behaviour of both individual and aggregated deep-sea benthopelagic animals. We provide detailed data-processing information for those interested in working with MBES water-column data, and a critical appraisal of the data in the context of aquatic ecosystem research. We consider future directions for deep-sea water-column echosounding, and reinforce the importance of measures to mitigate vessel avoidance in studies of aquatic ecosystems.

Association of Chronic Kidney Disease With Small Vessel Disease in Patients With Hypertensive Intracerebral Hemorrhage.

PubMed

Tsai, Yuan-Hsiung; Lee, Meng; Lin, Leng-Chieh; Chang, Sheng-Wei; Weng, Hsu-Huei; Yang, Jen-Tsung; Huang, Yen-Chu; Lee, Ming-Hsueh

2018-01-01

Chronic kidney disease (CKD) has been closely associated with hypertension and stroke. Although studies have reported the relationship between CKD and cerebral small vessel disease (SVD), the link between CKD, hypertension, and SVD is uncertain. The aim of this study was to investigate the association between CKD and SVD in patients with strictly hypertensive intracerebral hemorrhage (ICH). 142 patients with acute hypertensive ICH were enrolled in this study. Magnetic resonance imaging was performed to assess imaging markers for SVD. Patients were categorized into three CKD groups based on the degree of kidney dysfunction [glomerular filtration rate (GFR) in milliliters per minute per 1.73 m 2 ]: normal kidney function (GFR ≥ 90), mild kidney disease (60 ≤ GFR < 90), and moderate to severe kidney disease (GFR < 60). The prevalence rate of mild and moderate to severe CKD was 50 and 14.8%, respectively. The stage of CKD was associated with history of chronic hypertension ( p  = 0.046) as well as the prevalence rate of overall and deep cerebral microbleed (CMB) ( p  = 0.001 and p  = 0.002, respectively). The stage of CKD was a significant risk factor for deep white matter hyperintensity (WMH) (OR 1.848; 95% CI 1.022-3.343, p  = 0.042), overall CMB (OR 2.628; 95% CI 1.462-4.724, p  = 0.001), lobar CMB (OR 2.106; 95% CI 1.119-3.963, p  = 0.021), and deep CMB (OR 2.237; 95% CI 1.263-3.960, p  = 0.006), even after adjustment for confounders. In patients with hypertensive ICH, the prevalence of CKD is high even at the early stage of renal function impairment and is associated with the prevalence of CMB and deep WMH. These results reinforce the notion of a link between hypertensive vasculopathy, renal function impairment, and cerebral SVD.

Radioactive waste disposal in seas adjacent to the territory of the Russian Federation.

PubMed

Yablokov, A V

2001-01-01

The former USSR illegally dumped into the ocean liquid and solid radioactive wastes (RW) originating from nuclear-powered vessels and ships. The Russian President created a special Commission to analyse both the scale and consequences of this activity. According to documentary data and expert estimates at the Commission's disposal, the maximum activity of RW that entered the seas adjacent to Russian territory could have been as much as 2,500 kCi at the time of disposal. The greatest radio-ecological hazard comes from reactors from nuclear submarines and core plates of the nuclear icebreaker 'Lenin', which had spent nuclear fuel in place and which were dumped in shallow water in the Kara Sea near Novaya Zemlya. Editor's note: This article extracts material from a Commission which published a report produced in Russia in 1993. Numerous sources in many Ministries and other government agencies, noted in the text, formed the basis for the final draft. The authors of the draft report were A. Yablokov, V. Karasev, V. Rumyantsev, M. Kokeev, O. Petrov, V. Lystsov, A. Yemelyanenkov and P. Rubtsov. After approving the draft report, the Commission submitted the report to the President of the Russian Federation in February 1993. By Presidential decision, this report (after several technical corrections) was open to the public: it is known variously as 'the Yablokov Commission report, or more simply the 'Yablokov Report', the 'White Book' or 'Yablokov White Paper'. During April-May 1993, 500 copies were distributed among governmental agencies inside Russia, and abroad through a net of Russian Embassies. This article was later sent to Dr Mike Champ as part of the ongoing collections of papers on the Arctic published in this journal (edited by Champ et al.: 1997 'Contaminants in the Arctic', Marine Pollution Bulletin 35, pp. 203-385 and in Marine Pollution Bulletin 2000, vol. 40, pp. 801-868, and continued with the present collection).

Use of Gabor filters and deep networks in the segmentation of retinal vessel morphology

NASA Astrophysics Data System (ADS)

Leopold, Henry A.; Orchard, Jeff; Zelek, John; Lakshminarayanan, Vasudevan

2017-02-01

The segmentation of retinal morphology has numerous applications in assessing ophthalmologic and cardiovascular disease pathologies. The early detection of many such conditions is often the most effective method for reducing patient risk. Computer aided segmentation of the vasculature has proven to be a challenge, mainly due to inconsistencies such as noise, variations in hue and brightness that can greatly reduce the quality of fundus images. Accurate fundus and/or retinal vessel maps give rise to longitudinal studies able to utilize multimodal image registration and disease/condition status measurements, as well as applications in surgery preparation and biometrics. This paper further investigates the use of a Convolutional Neural Network as a multi-channel classifier of retinal vessels using the Digital Retinal Images for Vessel Extraction database, a standardized set of fundus images used to gauge the effectiveness of classification algorithms. The CNN has a feed-forward architecture and varies from other published architectures in its combination of: max-pooling, zero-padding, ReLU layers, batch normalization, two dense layers and finally a Softmax activation function. Notably, the use of Adam to optimize training the CNN on retinal fundus images has not been found in prior review. This work builds on prior work of the authors, exploring the use of Gabor filters to boost the accuracy of the system to 0.9478 during post processing. The mean of a series of Gabor filters with varying frequencies and sigma values are applied to the output of the network and used to determine whether a pixel represents a vessel or non-vessel.

Quantitative study of the microvasculature and its endothelial cells in the porcine iris.

PubMed

Yang, Hongfang; Yu, Paula K; Cringle, Stephen J; Sun, Xinghuai; Yu, Dao-Yi

2015-03-01

The roles of the iris microvasculature have been increasingly recognised in the pathogenesis of glaucoma and cataract; however limited information exists regarding the iris microvasculature and its endothelium. This study quantitatively assessed the iris microvascular network and its endothelium using intra-luminal micro-perfusion, fixation, and staining of the porcine iris. The temporal long posterior ciliary artery of 11 isolated porcine eyes was cannulated, perfusion-fixed and labelled using silver nitrate. The iris microvasculature was studied for its distribution, orders and endothelial morphometrics. The density of three layers of microvasculature was measured. Endothelial cell length and width were measured for each vessel order. The iris has an unusual vascular distribution which consisted of abundant large vessels in the middle of the iris stroma, branching over a relatively short distance to the microvasculature located in the superficial and deep stroma as well as the pupil edge. The average vascular density of the middle, superficial, and deep layers were 38.9 ± 1.93%, 10.9 ± 1.61% and 8.0 ± 0.79% respectively. Multiple orders of iris vessels (capillary, 6 orders of arteries, and 4 orders of veins) with relatively large capillary and input arteries (319.5 ± 25.6 μm) were found. Significant heterogeneity of vascular diameter and shape of the endothelia was revealed in different orders of the iris vasculature. Detailed information of topography and endothelium of the iris microvasculature combined with unique structural features of the iris may help us to further understand the physiological and pathogenic roles of the iris in relevant ocular diseases. Copyright © 2015 Elsevier Ltd. All rights reserved.

Optical coherence tomography (OCT) guided smart laser knife for cancer surgery (Conference Presentation)

NASA Astrophysics Data System (ADS)

Katta, Nitesh; Mcelroy, Austin; Estrada, Arnold; Milner, Thomas E.

2017-02-01

Neurological cancer surgeries require specialized tools that enhance imaging for precise cutting and removal of tissue without damaging adjacent neurological structures. The novel combination of high-resolution fast optical coherence tomography (OCT) alongside short pulsed nanosecond thulium (Tm) lasers offers stark advantages utilizing the superior beam quality, high volumetric tissue removal rates of thulium lasers with minimal residual thermal footprint in the tissue and avoiding damage to delicate sub-surface structures (e.g., nerves and microvessels); which has not been showcased before. A bench-top system is constructed, using a 15W 1940nm nanosecond pulsed Tm fiber laser (500uJ pulse energy, 100ns pulse duration, 30kHz repetition rate) for removing tissue and a swept source laser (1310±70nm, 100kHz sweep rate) is utilized for OCT imaging, forming a combined Tm/OCT system - a smart laser knife. The OCT image-guidance informs the Tm laser for cutting/removal of targeted tissue structures. Tissue phantoms were constructed to demonstrate surgical incision with blood vessel avoidance on the surface where 2mm wide 600um deep cuts are executed around the vessel using OCT to guide the procedure. Cutting up to delicate subsurface blood vessels (2mm deep) is demonstrated while avoiding damage to their walls. A tissue removal rate of 5mm^3/sec is obtained from the bench-top system. We constructed a blow-off model to characterize Tm cut depths taking into account the absorption coefficients and beam delivery systems to compute Arrhenius damage integrals. The model is used to compare predicted tissue removal rate and residual thermal injury with experimental values in response to Tm laser-tissue modification.

Deep-sea environment and biodiversity of the West African Equatorial margin

NASA Astrophysics Data System (ADS)

Sibuet, Myriam; Vangriesheim, Annick

2009-12-01

The long-term BIOZAIRE multidisciplinary deep-sea environmental program on the West Equatorial African margin organized in partnership between Ifremer and TOTAL aimed at characterizing the benthic community structure in relation with physical and chemical processes in a region of oil and gas interest. The morphology of the deep Congo submarine channel and the sedimentological structures of the deep-sea fan were established during the geological ZAIANGO project and helped to select study sites ranging from 350 to 4800 m water depth inside or near the channel and away from its influence. Ifremer conducted eight deep-sea cruises on board research vessels between 2000 and 2005. Standardized methods of sampling together with new technologies such as the ROV Victor 6000 and its associated instrumentation were used to investigate this poorly known continental margin. In addition to the study of sedimentary environments more or less influenced by turbidity events, the discovery of one of the largest cold seeps near the Congo channel and deep coral reefs extends our knowledge of the different habitats of this margin. This paper presents the background, objectives and major results of the BIOZAIRE Program. It highlights the work achieved in the 16 papers in this special issue. This synthesis paper describes the knowledge acquired at a regional and local scale of the Equatorial East Atlantic margin, and tackles new interdisciplinary questions to be answered in the various domains of physics, chemistry, taxonomy and ecology to better understand the deep-sea environment in the Gulf of Guinea.

Development of Automotive Liquid Hydrogen Storage Systems

NASA Astrophysics Data System (ADS)

Krainz, G.; Bartlok, G.; Bodner, P.; Casapicola, P.; Doeller, Ch.; Hofmeister, F.; Neubacher, E.; Zieger, A.

2004-06-01

Liquid hydrogen (LH2) takes up less storage volume than gas but requires cryogenic vessels. State-of-the-art applications for passenger vehicles consist of double-wall cylindrical tanks that hold a hydrogen storage mass of up to 10 kg. The preferred shell material of the tanks is stainless steel, since it is very resistant against hydrogen brittleness and shows negligible hydrogen permeation. Therefore, the weight of the whole tank system including valves and heat exchanger is more than 100 kg. The space between the inner and outer vessel is mainly used for thermal super-insulation purposes. Several layers of insulation foils and high vacuums of 10-3 Pa reduce the heat entry. The support structures, which keep the inner tank in position to the outer tank, are made of materials with low thermal conductivity, e.g. glass or carbon fiber reinforced plastics. The remaining heat in-leak leads to a boil-off rate of 1 to 3 percent per day. Active cooling systems to increase the stand-by time before evaporation losses occur are being studied. Currently, the production of several liquid hydrogen tanks that fulfill the draft of regulations of the European Integrated Hydrogen Project (EIHP) is being prepared. New concepts of lightweight liquid hydrogen storage tanks will be investigated.

Drafting Fundamentals. Drafting Module 1. Instructor's Guide.

ERIC Educational Resources Information Center

Missouri Univ., Columbia. Instructional Materials Lab.

This Missouri Vocational Instruction Management System instructor's drafting guide has been keyed to the drafting competency profile developed by state industry and education professionals. The guide contains a cross-reference table of instructional materials. Ten units cover drafting fundamentals: (1) introduction to drafting; (2) general safety;…

Rheolytic thrombectomy with use of the AngioJet-F105 catheter: preclinical evaluation of safety.

PubMed

Sharafuddin, M J; Hicks, M E; Jenson, M L; Morris, J E; Drasler, W J; Wilson, G J

1997-01-01

A preclinical evaluation of the safety of the AngioJet-F105 rheolytic thrombectomy catheter. The AngioJet-F105 catheter uses multiple retrograde high-speed fluid jets impinging on a primary aspiration lumen to create a hydrodynamic recirculation vortex that traps and fragments adjacent thrombus, with simultaneous evacuation of the resulting debris through the aspiration lumen. The effect of the AngioJet on treated vessels was evaluated in 10 canines. Vascular integrity on histopathologic examination and endothelial coverage on scanning electron microscopic study were examined in 15 vessel segments treated with the AngioJet-F105 catheter, compared with four vessel segments subjected to the Fogarty balloon maneuver, and 10 untreated vessel segments. The size distribution of particulate debris, upstream and downstream, after thrombectomy was determined in a flow-circuit model simulating the superficial femoral artery. Aliquots from the downstream effluent were then injected into the renal arteries of two healthy canines. The device caused only minimal focal endothelial denudation and no significant deep injury. No significant difference in endothelial coverage occurred in AngioJet-treated vessel segments compared to untreated control vessels (mean +/- standard deviation: 88.0% +/- 7.9% vs 89.7% +/- 11.6%, P = .77). Vessels treated with the Fogarty balloon pullback maneuver had significantly less residual endothelial coverage (58.0% +/- 8.0%, P < .03). Particulate microemboli in the effluent of the flow model accounted for 12% of the initial thrombus volume (0% > 100 microm, 99.83% < or = 10 microm). Histopathologic evaluation of the four renal beds injected with the resulting debris demonstrated no signs of necrosis. A moderate transient increase in plasma-free hemoglobin occurred, with a mild corresponding decrease in hematocrit. The AngioJet-F105 catheter resulted in only mild and focal injury to the treated vessels. The vast majority of resulting particulate debris consist of microscopic particles, without significant ischemic effect.

The role of invasive trophoblast in implantation and placentation of primates.

PubMed

Carter, Anthony M; Enders, Allen C; Pijnenborg, Robert

2015-03-05

We here review the evolution of invasive placentation in primates towards the deep penetration of the endometrium and its arteries in hominoids. The strepsirrhine primates (lemurs and lorises) have non-invasive, epitheliochorial placentation, although this is thought to be derived from a more invasive type. In haplorhine primates, there is differentiation of trophoblast at the blastocyst stage into syncytial and cellular trophoblast. Implantation involves syncytiotrophoblast that first removes the uterine epithelium then consolidates at the basal lamina before continuing into the stroma. In later stages of pregnancy, especially in Old World monkeys and apes, cytotrophoblast plays a greater role in the invasive process. Columns of trophoblast cells advance to the base of the implantation site where they spread out to form a cytotrophoblastic shell. In addition, cytotrophoblasts advance into the lumen of the spiral arteries. They are responsible for remodelling these vessels to form wide, low-resistance conduits. In human and great apes, there is additional invasion of the endometrium and its vessels by trophoblasts originating from the base of the anchoring villi. Deep trophoblast invasion that extends remodelling of the spiral arteries to segments in the inner myometrium evolved in the common ancestor of gorilla, chimp and human. © 2015 The Author(s) Published by the Royal Society. All rights reserved.

James Cameron discusses record dive and science concerns

NASA Astrophysics Data System (ADS)

Showstack, Randy; Balcerak, Ernie

2012-12-01

James Cameron, the explorer and filmmaker, led a 4 December panel at the AGU Fall Meeting in San Francisco to discuss his daring dive on 26 March to the bottom of the ocean in a one-person vertical "torpedo" submarine, the Deepsea Challenger, and to present some initial science findings from expedition samples and data. The dive touched the bottom of the Challenger Deep, a valley in the floor of the nearly 11-kilometer-deep Mariana Trench in the western Pacific Ocean. The vessel landed close to the same depth and at a location similar to where Don Walsh and Jacques Piccard descended in the Trieste bathyscaphe on 23 January 1960 at a then record-setting depth of 10,911 meters.

Acceptance criteria for welds in ASTM A106 grade B steel pipe and plate

NASA Technical Reports Server (NTRS)

Hudson, C. M.; Wright, D. B., Jr.; Leis, B. N.

1986-01-01

Based on the RECERT Program findings, NASA-Langley funded a fatigue study of code-unacceptable welds. Usage curves were developed which were based on the structural integrity of the welds. The details of this study are presented in NASA CR-178114. The information presented is a condensation and reinterpretation of the information in NASA CR-178114. This condensation and reinterpretation generated usage curves for welds having: (1) indications 0.20 -inch deep by 0.40-inch long, and (2) indications 0.195-inch deep by 8.4-inches long. These curves were developed using the procedures used in formulating the design curves in Section VIII, Division 2 of the American Society of Mechanical Engineers Boiler and Pressure Vessel Code.

Functional Drafting, Drafting--Intermediate: 9255.02.

ERIC Educational Resources Information Center

Dade County Public Schools, Miami, FL.

The course consists of six instructional blocks totaling 135 clock hours: (1) functional drafting, (2) threads and fasteners, (3) pictorial drawings, (4) introduction to electronic drafting, (5) introduction to piping drafting, and (6) Quinmester posttest. Mastery of skills indicated in Drafting-Basic--9255.01 is a prerequisite. In the functional…

76 FR 41808 - Draft Environmental Impact Statement and Draft Habitat Conservation Plan for Oncor Electric...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-15

...] Draft Environmental Impact Statement and Draft Habitat Conservation Plan for Oncor Electric Delivery..., announce the availability of the draft environmental impact statement and the draft Oncor Electric Delivery... Oncor Electric Delivery Company, LLC (Applicant; Oncor), and (2) That the Applicant has developed a...

Hydrodynamic Modeling of the Deep Impact Mission into Comet Tempel 1

NASA Astrophysics Data System (ADS)

Sorli, Kya; Remington, Tané; Bruck Syal, Megan

2018-01-01

Kinetic impact is one of the primary strategies to deflect hazardous objects off of an Earth-impacting trajectory. The only test of a small-body impact is the 2005 Deep Impact mission into comet Tempel 1, where a 366-kg mass impactor collided at ~10 km/s into the comet, liberating an enormous amount of vapor and ejecta. Code comparisons with observations of the event represent an important source of new information about the initial conditions of small bodies and an extraordinary opportunity to test our simulation capabilities on a rare, full-scale experiment. Using the Adaptive Smoothed Particle Hydrodynamics (ASPH) code, Spheral, we explore how variations in target material properties such as strength, composition, porosity, and layering affect impact results, in order to best match the observed crater size and ejecta evolution. Benchmarking against this unique small-body experiment provides an enhanced understanding of our ability to simulate asteroid or comet response to future deflection missions. This work was performed under the auspices of the U.S. Department of Energy by Lawrence Livermore National Laboratory under Contract DE-AC52-07NA27344. LLNL-ABS-739336-DRAFT.

A Study of Stranding of Juvenile Salmon by Ship Wakes Along the Lower Columbia River Using a Before-and-After Design: Before-Phase Results

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pearson, Walter H.; Skalski, J R.; Sobocinski, Kathryn L.

2006-02-01

Ship wakes produced by deep-draft vessels transiting the lower Columbia River have been observed to cause stranding of juvenile salmon. Proposed deepening of the Columbia River navigation channel has raised concerns about the potential impact of the deepening project on juvenile salmon stranding. The Portland District of the U.S. Army Corps of Engineers requested that the Pacific Northwest National Laboratory design and conduct a study to assess stranding impacts that may be associated with channel deepening. The basic study design was a multivariate analysis of covariance of field observations and measurements under a statistical design for a before and aftermore » impact comparison. We have summarized field activities and statistical analyses for the ?before? component of the study here. Stranding occurred at all three sampling sites and during all three sampling seasons (Summer 2004, Winter 2005, and Spring 2005), for a total of 46 stranding events during 126 observed vessel passages. The highest occurrence of stranding occurred at Barlow Point, WA, where 53% of the observed events resulted in stranding. Other sites included Sauvie Island, OR (37%) and County Line Park, WA (15%). To develop an appropriate impact assessment model that accounted for relevant covariates, regression analyses were conducted to determine the relationships between stranding probability and other factors. Nineteen independent variables were considered as potential factors affecting the incidence of juvenile salmon stranding, including tidal stage, tidal height, river flow, current velocity, ship type, ship direction, ship condition (loaded/unloaded), ship speed, ship size, and a proxy variable for ship kinetic energy. In addition to the ambient and ship characteristics listed above, site, season, and fish density were also considered. Although no single factor appears as the primary factor for stranding, statistical analyses of the covariates resulted in the following equations: (1) Stranding Probability {approx} Location + Kinetic Energy Proxy + Tidal Height + Salmonid Density + Kinetic energy proxy ? Tidal Height + Tidal Height x Salmonid Density. (2) Stranding Probability {approx} Location + Total Wave Distance + Salmonid Density Index. (3) Log(Total Wave Height) {approx} Ship Block + Tidal Height + Location + Ship Speed. (4) Log(Total Wave Excursion Across the Beach) {approx} Location + Kinetic Energy Proxy + Tidal Height The above equations form the basis for a conceptual model of the factors leading to salmon stranding. The equations also form the basis for an approach for assessing impacts of dredging under the before/after study design.« less

A Computer Model of Drafting Effects on Collective Behavior in Elite 10,000-m Runners.

PubMed

Trenchard, Hugh; Renfree, Andrew; Peters, Derek M

2017-03-01

Drafting in cycling influences collective behavior of pelotons. Although evidence for collective behavior in competitive running events exists, it is not clear if this results from energetic savings conferred by drafting. This study modeled the effects of drafting on behavior in elite 10,000-m runners. Using performance data from a men's elite 10,000-m track running event, computer simulations were constructed using Netlogo 5.1 to test the effects of 3 different drafting quantities on collective behavior: no drafting, drafting to 3 m behind with up to ~8% energy savings (a realistic running draft), and drafting up to 3 m behind with up to 38% energy savings (a realistic cycling draft). Three measures of collective behavior were analyzed in each condition: mean speed, mean group stretch (distance between first- and last-placed runner), and runner-convergence ratio (RCR), which represents the degree of drafting benefit obtained by the follower in a pair of coupled runners. Mean speeds were 6.32 ± 0.28, 5.57 ± 0.18, and 5.51 ± 0.13 m/s in the cycling-draft, runner-draft, and no-draft conditions, respectively (all P < .001). RCR was lower in the cycling-draft condition but did not differ between the other 2. Mean stretch did not differ between conditions. Collective behaviors observed in running events cannot be fully explained through energetic savings conferred by realistic drafting benefits. They may therefore result from other, possibly psychological, processes. The benefits or otherwise of engaging in such behavior are as yet unclear.

[Treatment of otorhinolaryngologic diseases of deficient heat type with Professor XIE Qiang's Tihu Guanding needling method].

PubMed

Chen, Dan; Xie, Qiange; Huang, Bing-Lin

2014-01-01

Professor XIE Qiang's Tihu Guanding needling method, a kind of acupuncture method which takes acupoints of the Conception Vessel as the primary and acupoints of the Governor Vessel as the secondary. Acupoints Lianquan (CV 23), Tiantu (CV 22), Qihai (CV 6), Zhongwan (CV 12), Baihui (GV 20) and Dazhui (GV 14) are adopted as the basic ones. Other points can be added according to various symptoms, for instance, Yingxiang (LI 20) and Yintang (GV 29) for rhinopathy, Tinggong (SI 19) and Yifeng (TE 17) for otopathy, Yan'an (Professor XIE's experience) and Shanglianquan (EX-HN 21) for pharyngopathy and Kaiyin 1 (Professor XIE's experience) and Kaiyin 2 (Professor XIE's experience) for laryngopathy. During the needle retention, rotation manipulation should be done every 5 min at Lianquan (CV 23). And the patient should be told to put the tip of one's tongue at the the palate as well as to do deep breathing to communicate the Conception Vessel and the Governor Vessel. Moxibustion is adopted at Yongquan (KI 1) to induce the up floating fire to mingmen (where the primary yang is stored). The therapeutic effect on treatment of persistent otorhinolaryngologic diseases with the above mentioned method is approve to be good.

Targeted disruption of deep-lying neocortical microvessels in rat using ultrashort laser pulses

NASA Astrophysics Data System (ADS)

Nishimura, Nozomi; Schaffer, Christopher B.; Friedman, Beth; Tsai, Philbert S.; Lyden, Patrick D.; Kleinfeld, David

2004-06-01

The study of neurovascular diseases such as vascular dementia and stroke require novel models of targeted vascular disruption in the brain. We describe a model of microvascular disruption in rat neocortex that uses ultrashort laser pulses to induce localized injury to specific targeted microvessels and uses two-photon microscopy to monitor and guide the photodisruption process. In our method, a train of high-intensity, 100-fs laser pulses is tightly focused into the lumen of a blood vessel within the upper 500 μm of cortex. Photodisruption induced by these laser pulses creates injury to a single vessel located at the focus of the laser, leaving the surrounding tissue intact. This photodisruption results in three modalities of localized vascular injury. At low power, blood plasma extravasation can be induced. The vessel itself remains intact, while serum is extravasated into the intercellular space. Localized ischemia caused by an intravascular clot results when the photodisruption leads to a brief disturbance of the vascular walls that initiates an endogenous clotting cascade. The formation of a localized thrombus stops the blood flow at the location of the photodisruption. A hemorrhage, defined as a large extravasation of blood including plasma and red blood cells, results when higher laser power is used. The targeted vessel does not remain intact.

Endothelial SRF/MRTF ablation causes vascular disease phenotypes in murine retinae

PubMed Central

Weinl, Christine; Riehle, Heidemarie; Park, Dongjeong; Stritt, Christine; Beck, Susanne; Huber, Gesine; Wolburg, Hartwig; Olson, Eric N.; Seeliger, Mathias W.; Adams, Ralf H.; Nordheim, Alfred

2013-01-01

Retinal vessel homeostasis ensures normal ocular functions. Consequently, retinal hypovascularization and neovascularization, causing a lack and an excess of vessels, respectively, are hallmarks of human retinal pathology. We provide evidence that EC-specific genetic ablation of either the transcription factor SRF or its cofactors MRTF-A and MRTF-B, but not the SRF cofactors ELK1 or ELK4, cause retinal hypovascularization in the postnatal mouse eye. Inducible, EC-specific deficiency of SRF or MRTF-A/MRTF-B during postnatal angiogenesis impaired endothelial tip cell filopodia protrusion, resulting in incomplete formation of the retinal primary vascular plexus, absence of the deep plexi, and persistence of hyaloid vessels. All of these features are typical of human hypovascularization-related vitreoretinopathies, such as familial exudative vitreoretinopathies including Norrie disease. In contrast, conditional EC deletion of Srf in adult murine vessels elicited intraretinal neovascularization that was reminiscent of the age-related human pathologies retinal angiomatous proliferation and macular telangiectasia. These results indicate that angiogenic homeostasis is ensured by differential stage-specific functions of SRF target gene products in the developing versus the mature retinal vasculature and suggest that the actin-directed MRTF-SRF signaling axis could serve as a therapeutic target in the treatment of human vascular retinal diseases. PMID:23563308

Endothelial SRF/MRTF ablation causes vascular disease phenotypes in murine retinae.

PubMed

Weinl, Christine; Riehle, Heidemarie; Park, Dongjeong; Stritt, Christine; Beck, Susanne; Huber, Gesine; Wolburg, Hartwig; Olson, Eric N; Seeliger, Mathias W; Adams, Ralf H; Nordheim, Alfred

2013-05-01

Retinal vessel homeostasis ensures normal ocular functions. Consequently, retinal hypovascularization and neovascularization, causing a lack and an excess of vessels, respectively, are hallmarks of human retinal pathology. We provide evidence that EC-specific genetic ablation of either the transcription factor SRF or its cofactors MRTF-A and MRTF-B, but not the SRF cofactors ELK1 or ELK4, cause retinal hypovascularization in the postnatal mouse eye. Inducible, EC-specific deficiency of SRF or MRTF-A/MRTF-B during postnatal angiogenesis impaired endothelial tip cell filopodia protrusion, resulting in incomplete formation of the retinal primary vascular plexus, absence of the deep plexi, and persistence of hyaloid vessels. All of these features are typical of human hypovascularization-related vitreoretinopathies, such as familial exudative vitreoretinopathies including Norrie disease. In contrast, conditional EC deletion of Srf in adult murine vessels elicited intraretinal neovascularization that was reminiscent of the age-related human pathologies retinal angiomatous proliferation and macular telangiectasia. These results indicate that angiogenic homeostasis is ensured by differential stage-specific functions of SRF target gene products in the developing versus the mature retinal vasculature and suggest that the actin-directed MRTF-SRF signaling axis could serve as a therapeutic target in the treatment of human vascular retinal diseases.

Digital Radiography Using Digital Detector Arrays Fulfills Critical Applications for Offshore Pipelines

NASA Astrophysics Data System (ADS)

Moreira, EdsonVasques; Barbosa Rabello, JoséMaurício; Pereira, MarcelodosSantos; Lopes, RicardoTadeu; Zscherpel, Uwe

2010-12-01

Digital radiography in the inspection of welded pipes to be installed under deep water offshore gas and oil pipelines, like a presalt in Brazil, in the paper has been investigated. The aim is to use digital radiography for nondestructive testing of welds as it is already in use in the medical, aerospace, security, automotive, and petrochemical sectors. Among the current options, the DDA (Digital Detector Array) is considered as one of the best solutions to replace industrial films, as well as to increase the sensitivity to reduce the inspection cycle time. This paper shows the results of this new technique, comparing it to radiography with industrial films systems. In this paper, 20 test specimens of longitudinal welded pipe joints, specially prepared with artificial defects like cracks, lack of fusion, lack of penetration, and porosities and slag inclusions with varying dimensions and in 06 different base metal wall thicknesses, were tested and a comparison of the techniques was made. These experiments verified the purposed rules for parameter definitions and selections to control the required digital radiographic image quality as described in the draft international standard ISO/DIS 10893-7. This draft is first standard establishing the parameters for digital radiography on weld seam of welded steel pipes for pressure purposes to be used on gas and oil pipelines.

The Asian arowana (Scleropages formosus) genome provides new insights into the evolution of an early lineage of teleosts

PubMed Central

Bian, Chao; Hu, Yinchang; Ravi, Vydianathan; Kuznetsova, Inna S.; Shen, Xueyan; Mu, Xidong; Sun, Ying; You, Xinxin; Li, Jia; Li, Xiaofeng; Qiu, Ying; Tay, Boon-Hui; Thevasagayam, Natascha May; Komissarov, Aleksey S.; Trifonov, Vladimir; Kabilov, Marsel; Tupikin, Alexey; Luo, Jianren; Liu, Yi; Song, Hongmei; Liu, Chao; Wang, Xuejie; Gu, Dangen; Yang, Yexin; Li, Wujiao; Polgar, Gianluca; Fan, Guangyi; Zeng, Peng; Zhang, He; Xiong, Zijun; Tang, Zhujing; Peng, Chao; Ruan, Zhiqiang; Yu, Hui; Chen, Jieming; Fan, Mingjun; Huang, Yu; Wang, Min; Zhao, Xiaomeng; Hu, Guojun; Yang, Huanming; Wang, Jian; Wang, Jun; Xu, Xun; Song, Linsheng; Xu, Gangchun; Xu, Pao; Xu, Junmin; O’Brien, Stephen J.; Orbán, László; Venkatesh, Byrappa; Shi, Qiong

2016-01-01

The Asian arowana (Scleropages formosus), one of the world’s most expensive cultivated ornamental fishes, is an endangered species. It represents an ancient lineage of teleosts: the Osteoglossomorpha. Here, we provide a high-quality chromosome-level reference genome of a female golden-variety arowana using a combination of deep shotgun sequencing and high-resolution linkage mapping. In addition, we have also generated two draft genome assemblies for the red and green varieties. Phylogenomic analysis supports a sister group relationship between Osteoglossomorpha (bonytongues) and Elopomorpha (eels and relatives), with the two clades together forming a sister group of Clupeocephala which includes all the remaining teleosts. The arowana genome retains the full complement of eight Hox clusters unlike the African butterfly fish (Pantodon buchholzi), another bonytongue fish, which possess only five Hox clusters. Differential gene expression among three varieties provides insights into the genetic basis of colour variation. A potential heterogametic sex chromosome is identified in the female arowana karyotype, suggesting that the sex is determined by a ZW/ZZ sex chromosomal system. The high-quality reference genome of the golden arowana and the draft assemblies of the red and green varieties are valuable resources for understanding the biology, adaptation and behaviour of Asian arowanas. PMID:27089831

76 FR 57760 - Notice of Availability of Draft Resource Management Plan and Draft Environmental Impact Statement...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-16

... Availability of Draft Resource Management Plan and Draft Environmental Impact Statement for the Colorado River... prepared a Draft Resource Management Plan (RMP) and Draft Environmental Impact Statement (EIS) for the... alternative) seeks to allocate limited resources among competing human interests, land uses, and conservation...

76 FR 59732 - Draft Environmental Impact Statement and Draft Habitat Conservation Plan for Oncor Electric...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-27

...] Draft Environmental Impact Statement and Draft Habitat Conservation Plan for Oncor Electric Delivery... availability of the draft environmental impact statement (DEIS) and the draft Oncor Electric Delivery Company... announced that Oncor Electric Delivery Company, LLC, has applied under section 10(a)(1)(B) of the Endangered...

Ecological evaluation of proposed dredged material from Richmond Harbor Deepening Project and the intensive study of the Turning Basin

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pinza, M.R.; Mayhew, H.L.; Karle, L.M.

Richmond Harbor is on the eastern shoreline of central San Francisco Bay and its access channels and several of the shipping berths are no longer wide or deep enough to accommodate modem deeper-draft vessels. The Water Resources Development Act of 1986 (PL99-662) authorized the US Army Corps of Engineers (USACE), San Francisco District to deepen and widen the navigation channels in Richmond Harbor. Several options for disposal of the material from this dredging project are under consideration by USACE: disposal within San Francisco Bay, at open-ocean disposal sites, or at uplands disposal sites. Purpose of this study was to conductmore » comprehensive evaluations, including chemical, biological, and bioaccumulation testing of sediments in selected areas of Richmond Harbor. This information was required by the Environmental Protection Agency (EPA) and USACE. Battelle/Marine Sciences Laboratory collected 20 core samples, both 4-in. and 12-in., to a project depth of -40 ft mean lower low water (MLLW) (-38 ft MLLW plus 2 ft of overdepth) using a vibratory-hammer core. These 20 field samples were combined to form five test composites plus an older bay mud (OBM) composite that were analyzed for physical/chemical parameters, biological toxicity, and tissue chemistry. Solid-phase tests were conducted with the amphipod, Rhepoxynius abronius; the clam, Macoma nasuta; and the polychaete worm, Nephtys caecoides. Suspended-particulate-phase (SPP) tests were conducted with the sanddab, Citharichthys stigmaeus; the mysid, Holmesimysis costata; and the bivalve, Mytilus galloprovincialis. Bioaccumulation of contaminants was measured in tissues of Macoma nasuta and Nereis virens. Sediments from one ocean reference sediment, and two in-bay reference sediments, were tested concurrently. Results from analysis of the five test treatments were statistically compared with the reference sediment R-OS in the first five sections of this report.« less

Entity Linking Leveraging the GeoDeepDive Cyberinfrastructure and Managing Uncertainty with Provenance.

NASA Astrophysics Data System (ADS)

Maio, R.; Arko, R. A.; Lehnert, K.; Ji, P.

2017-12-01

Unlocking the full, rich, network of links between the scientific literature and the real world entities to which data correspond - such as field expeditions (cruises) on oceanographic research vessels and physical samples collected during those expeditions - remains a challenge for the geoscience community. Doing so would enable data reuse and integration on a broad scale; making it possible to inspect the network and discover, for example, all rock samples reported in the scientific literature found within 10 kilometers of an undersea volcano, and associated geochemical analyses. Such a capability could facilitate new scientific discoveries. The GeoDeepDive project provides negotiated access to 4.2+ million documents from scientific publishers, enabling text and document mining via a public API and cyberinfrastructure. We mined this corpus using entity linking techniques, which are inherently uncertain, and recorded provenance information about each link. This opens the entity linking methodology to scrutiny, and enables downstream applications to make informed assessments about the suitability of an entity link for consumption. A major challenge is how to model and disseminate the provenance information. We present results from entity linking between journal articles, research vessels and cruises, and physical samples from the Petrological Database (PetDB), and incorporate Linked Data resources such as cruises in the Rolling Deck to Repository (R2R) catalog where possible. Our work demonstrates the value and potential of the GeoDeepDive cyberinfrastructure in combination with Linked Data infrastructure provided by the EarthCube GeoLink project. We present a research workflow to capture provenance information that leverages the World Wide Web Consortium (W3C) recommendation PROV Ontology.

In vivo study comparing an X-shaped polymethylmethacrylate and a cylindrical collagen implant for deep sclerectomy.

PubMed

Codreanu, Andrea; Tran, Hoai V; Wiaux, Christophe; Mansouri, Kaweh; Roy, Sylvain; Mermoud, Andre; Schnyder, Corinne

2011-03-01

Study in vivo characteristics of a polymethylmethacrylate (PMMA) implant compared to the standard cylindrical collagen implant for deep sclerectomy (DS). Six-month comparative study. Twenty eyes of ten rabbits. Eyes were randomized to have DS with PMMA implant in one eye and collagen implant in the opposite eye. The growth of the new subconjunctival drainage vessels was assessed by combined fluorescein and indocyanin green anterior segment angiography; intrascleral and subconjunctival blebs were imaged by ultrasound biomicroscopy (UBM). At six months, outflow facility (C) was measured by anterior chamber perfusion and portions of one side of the DS were compared to portions on the 180° opposite side and native sclera on histology. The mean IOP preoperatively and at one, four, twelve, and twenty-four weeks was comparable in both groups (P > 0.1). UBM showed a statistically insignificant quicker regression of the subconjunctival bleb as well as a durable intrascleral lake in the PMMA group (P > 0.05). New drainage vessels were initially observed one month after surgery; they were more numerous in the PMMA group on angiographic and histological findings at 6 months (P < 0.05). The mean C increased significantly after surgery compared to preoperative values (P < 0.05) and no difference was observed between the implants (0.24 ± 0.06 µl/min/mmHg [PMMA] and 0.23 ± 0.07 µl/min/mmHg [collagen implant]) (P = 0.39). Deep sclerectomy performed with PMMA or collagen implants showed similar IOP lowering effects, outflow facility increase, and degree of inflammatory reaction. © 2010 The Authors. Clinical and Experimental Ophthalmology © 2010 Royal Australian and New Zealand College of Ophthalmologists.

Multimodal ultrasonographic assessment of leiomyosarcoma of the femoral vein in a patient misdiagnosed as having deep vein thrombosis: A case report.

PubMed

Zhang, Mei; Yan, Feng; Huang, Bin; Wu, Zhoupeng; Wen, Xiaorong

2017-11-01

Primary leiomyosarcoma (LMS) of the vein is a rare tumor that arises from the smooth muscle cells of the vessel wall and has an extremely poor prognosis. This tumor can occur in vessels such as the inferior vena cava, great saphenous vein, femoral vein, iliac vein, popliteal vein, and renal vein; the inferior vena cava is the most common site. LMS of the femoral vein can result in edema and pain in the lower extremity; therefore, it is not easy to be differentiated from deep vein thrombosis (DVT). Moreover, virtually no studies have described the ultrasonographic features of LMS of the vein in detail. We present a case of a 55-year-old woman with LMS of the left femoral vein that was misdiagnosed as having deep vein thrombosis (DVT) on initial ultrasonographic examination. The patient began to experience edema and pain in her left leg seven months previously. She was diagnosed as having DVT on initial ultrasonographic examination, but the DVT treatment that she had received for 7 months failed to improve the status of her left lower limb. She subsequently underwent re-examination by means of a multimodal ultrasonographic imaging approach (regular B-mode imaging, color Doppler imaging, pulsed-wave Doppler imaging, contrast-enhanced ultrasonography), which confirmed a diagnosis of LMS. This patient was treated successfully with surgery. This case demonstrates that use of multiple ultrasonographic imaging techniques can be helpful to diagnose LMS accurately. Detection of vasculature in a dilated vein filled with a heterogeneous hypoechoic substance on ultrasonography is a sign of a tumor. The pitfall of misdiagnosing this tumor as DVT is a useful reminder.

Multimodal ultrasonographic assessment of leiomyosarcoma of the femoral vein in a patient misdiagnosed as having deep vein thrombosis

PubMed Central

Zhang, Mei; Yan, Feng; Huang, Bin; Wu, Zhoupeng; Wen, Xiaorong

2017-01-01

Abstract Rationale: Primary leiomyosarcoma (LMS) of the vein is a rare tumor that arises from the smooth muscle cells of the vessel wall and has an extremely poor prognosis. This tumor can occur in vessels such as the inferior vena cava, great saphenous vein, femoral vein, iliac vein, popliteal vein, and renal vein; the inferior vena cava is the most common site. LMS of the femoral vein can result in edema and pain in the lower extremity; therefore, it is not easy to be differentiated from deep vein thrombosis (DVT). Moreover, virtually no studies have described the ultrasonographic features of LMS of the vein in detail. Patient concerns: We present a case of a 55-year-old woman with LMS of the left femoral vein that was misdiagnosed as having deep vein thrombosis (DVT) on initial ultrasonographic examination. The patient began to experience edema and pain in her left leg seven months previously. She was diagnosed as having DVT on initial ultrasonographic examination, but the DVT treatment that she had received for 7 months failed to improve the status of her left lower limb. Diagnoses: She subsequently underwent re-examination by means of a multimodal ultrasonographic imaging approach (regular B-mode imaging, color Doppler imaging, pulsed-wave Doppler imaging, contrast-enhanced ultrasonography), which confirmed a diagnosis of LMS. Interventions: This patient was treated successfully with surgery. Outcomes: This case demonstrates that use of multiple ultrasonographic imaging techniques can be helpful to diagnose LMS accurately. Detection of vasculature in a dilated vein filled with a heterogeneous hypoechoic substance on ultrasonography is a sign of a tumor. Lessons: The pitfall of misdiagnosing this tumor as DVT is a useful reminder. PMID:29145269

Automatic draft reading based on image processing

NASA Astrophysics Data System (ADS)

Tsujii, Takahiro; Yoshida, Hiromi; Iiguni, Youji

2016-10-01

In marine transportation, a draft survey is a means to determine the quantity of bulk cargo. Automatic draft reading based on computer image processing has been proposed. However, the conventional draft mark segmentation may fail when the video sequence has many other regions than draft marks and a hull, and the estimated waterline is inherently higher than the true one. To solve these problems, we propose an automatic draft reading method that uses morphological operations to detect draft marks and estimate the waterline for every frame with Canny edge detection and a robust estimation. Moreover, we emulate surveyors' draft reading process for getting the understanding of a shipper and a receiver. In an experiment in a towing tank, the draft reading error of the proposed method was <1 cm, showing the advantage of the proposed method. It is also shown that accurate draft reading has been achieved in a real-world scene.

RGD-conjugated two-photon absorbing near-IR emitting fluorescent probes for tumor vascular imaging (Conference Presentation)

NASA Astrophysics Data System (ADS)

Belfield, Kevin D.; Yue, Xiling; Morales, Alma R.; Githaiga, Grace W.; Woodward, Adam W.; Tang, Simon; Sawada, Junko; Komatsu, Masanobu; Liu, Xuan

2016-03-01

Observation of the activation and inhibition of angiogenesis processes is important in the progression of cancer. Application of targeting peptides, such as a small peptide that contains adjacent L-arginine (R), glycine (G) and L-aspartic acid (D) residues can afford high selectivity and deep penetration in vessel imaging. To facilitate deep tissue vasculature imaging, probes that can be excited via two-photon absorption (2PA) in the near-infrared (NIR) and subsequently emit in the NIR are essential. In this study, the enhancement of tissue image quality with RGD conjugates was investigated with new NIR-emitting pyranyl fluorophore derivatives in two-photon fluorescence microscopy. Linear and nonlinear photophysical properties of the new probes were comprehensively characterized; significantly the probes exhibited good 2PA over a broad spectral range from 700-1100 nm. Cell and tissue images were then acquired and examined, revealing deep penetration and high contrast with the new pyranyl RGD-conjugates up to 350 μm in tumor tissue.

Vascular abnormalities of the distal deep digital flexor tendon in 8 draught horses identified on histological examination.

PubMed

Crişan, Melania Ioana; Damian, Aurel; Gal, Adrian; Miclăuş, Viorel; Cernea, Cristina L; Denoix, Jean-Marie

2013-08-01

The purpose of this study was to provide a detailed description of the vascular changes in the distal part of deep digital flexor tendon (DDFT). Eight isolated forelimbs were collected from 8 horses with DDF tendinopathy diagnosed post-mortem by ultrasound and gross anatomopathological examination. The samples were fixed in 10% neutral buffered formalin, softened in 4% phenol and dehydrated with ethylic alcohol. Goldner's Trichrome staining method was used. The histopathological examination revealed vascular proliferation associated with structural disorders of blood vessels. Angiogenesis, fibroplasia and consecutive hypertrophy of the vascular wall with or without vascular occlusion were the most common findings. Other histopathological findings were: endothelial cell edema, progressive metaplasia from squamous to cubic cells, vascular wall hyalinization, endothelial cells apoptosis/necrosis and endothelial desquamation. These results demonstrated damage of the distal deep digital flexor tendon vasculature which may progressively alter the structural integrity of the tendon and contribute to degenerative lesions. Copyright © 2013 Elsevier Ltd. All rights reserved.

Internal carotid artery pseudoaneurysm with life-threatening epistaxis as a complication of deep neck space infection.

PubMed

da Silva, Paulo Sérgio Lucas; Waisberg, Daniel Reis

2011-05-01

Pseudoaneurysm of the cervical internal carotid artery is a very rare, potentially fatal complication of a neck space infection in children associated with high mortality and morbidity. A 3-year-old boy presented with spontaneous massive epistaxis 45 days after a deep neck space infection caused by a peritonsillar abscess. During nasopharyngeal packing, he evolved with cardiac arrest. Intra-arterial angiography was then performed that revealed a large pseudoaneurysm. Endovascular treatment using detachable balloons achieved complete exclusion of the pseudoaneurysm. The child made an uneventful recovery and was discharged with mild left hemiparesis and no deficit of sensory or cognitive functions. Pseudoaneurysms of the internal carotid artery after a deep neck space infection can be associated with delayed and potentially fatal massive epistaxis. Furthermore, a regional (ie, extranasal) blood vessel should be promptly investigated when there are signs of hypovolemic shock. A high level of suspicion and definitive treatment are essential for successful management of these patients.

Deep in vivo two-photon imaging of blood vessels with a new dye encapsulated in pluronic nanomicelles

NASA Astrophysics Data System (ADS)

Maurin, Mathieu; Stéphan, Olivier; Vial, Jean-Claude; Marder, Seth R.; van der Sanden, Boudewijn

2011-03-01

Our purpose is to test if Pluronic® fluorescent nanomicelles can be used for in vivo two-photon imaging of both the normal and the tumor vasculature. The nanomicelles were obtained after encapsulating a hydrophobic two-photon dye: di-stryl benzene derivative, in Pluronic block copolymers. Their performance with respect to imaging depth, blood plasma staining, and diffusion across the tumor vascular endothelium is compared to a classic blood pool dye Rhodamin B dextran (70 kDa) using two-photon microscopy. Pluronic nanomicelles show, like Rhodamin B dextran, a homogeneous blood plasma staining for at least 1 h after intravenous injection. Their two-photon imaging depth is similar in normal mouse brain, using 10 times less injected mass. In contrast with Rhodamin B dextran, no extravasation is observed in leaky tumor vessels due to their large size: 20-100 nm. In conclusion, Pluronic nanomicelles can be used as a blood pool dye, even in leaky tumor vessels. The use of Pluronic block copolymers is a valuable approach for encapsulating two-photon fluorescent dyes that are hydrophobic and not suitable for intravenous injection.

Calibration of Seismic Sources during a Test Cruise with the new RV SONNE

NASA Astrophysics Data System (ADS)

Engels, M.; Schnabel, M.; Damm, V.

2015-12-01

During autumn 2014, several test cruises of the brand new German research vessel SONNE were carried out before the first official scientific cruise started in December. In September 2014, BGR conducted a seismic test cruise in the British North Sea. RV SONNE is a multipurpose research vessel and was also designed for the mobile BGR 3D seismic equipment, which was tested successfully during the cruise. We spend two days for calibration of the following seismic sources of BGR: G-gun array (50 l @ 150 bar) G-gun array (50 l @ 207 bar) single GI-gun (3.4 l @ 150 bar) For this experiment two hydrophones (TC4042 from Reson Teledyne) sampling up to 48 kHz were fixed below a drifting buoy at 20 m and 60 m water depth - the sea bottom was at 80 m depth. The vessel with the seismic sources sailed several up to 7 km long profiles around the buoy in order to cover many different azimuths and distances. We aimed to measure sound pressure level (SPL) and sound exposure level (SEL) under the conditions of the shallow North Sea. Total reflections and refracted waves dominate the recorded wave field, enhance the noise level and partly screen the direct wave in contrast to 'true' deep water calibration based solely on the direct wave. Presented are SPL and RMS power results in time domain, the decay with distance along profiles, and the somehow complicated 2D sound radiation pattern modulated by topography. The shading effect of the vessel's hull is significant. In frequency domain we consider 1/3 octave levels and estimate the amount of energy in frequency ranges not used for reflection seismic processing. Results are presented in comparison of the three different sources listed above. We compare the measured SPL decay with distance during this experiment with deep water modeling of seismic sources (Gundalf software) and with published results from calibrations with other marine seismic sources under different conditions: E.g. Breitzke et al. (2008, 2010) with RV Polarstern, Tolstoy et al. (2004) with RV Ewing and Tolstoy et al. (2009) with RV Langseth, and Crone et al. (2014) with RV Langseth.

Drafting: Current Trends and Future Practices

ERIC Educational Resources Information Center

Jensen, C.

1976-01-01

Various research findings are reported on drafting trends which the author feels should be incorporated into teaching drafting: (1) true position and geometric tolerancing, (2) decimal and metric dimensioning, (3) functional drafting, (4) automated drafting, and (5) drawing reproductions. (BP)

Mississippi Curriculum Framework for Drafting and Design Technology (Program CIP: 48.0102--Architectural Drafting Technology) (Program CIP: 48.0101--General Drafting). Postsecondary Programs.

ERIC Educational Resources Information Center

Mississippi Research and Curriculum Unit for Vocational and Technical Education, State College.

This document, which is intended for use by community and junior colleges throughout Mississippi, contains curriculum frameworks for the two course sequences of the state's postsecondary-level drafting and design technology program: architectural drafting technology and drafting and design technology. Presented first are a program description and…

Ultrasound assessment of the posterior circumflex humeral artery in elite volleyball players: Aneurysm prevalence, anatomy, branching pattern and vessel characteristics.

PubMed

van de Pol, Daan; Maas, Mario; Terpstra, Aart; Pannekoek-Hekman, Marja; Alaeikhanehshir, Sena; Kuijer, P Paul F M; Planken, R Nils

2017-03-01

To determine the prevalence of posterior circumflex humeral artery (PCHA) aneurysms and vessel characteristics of the PCHA and deep brachial artery (DBA) in elite volleyball players. Two-hundred and eighty players underwent standardized ultrasound assessment of the dominant arm by a vascular technologist. Assessment included determination of PCHA aneurysms (defined as segmental vessel dilatation ≥150 %), PCHA and DBA anatomy, branching pattern, vessel course and diameter. The PCHA and DBA were identified in 100 % and 93 % (260/280) of cases, respectively. The prevalence of PCHA aneurysms was 4.6 % (13/280). All aneurysms were detected in proximal PCHA originating from the axillary artery (AA). The PCHA originated from the AA in 81 % of cases (228/280), and showed a curved course dorsally towards the humeral head in 93 % (211/228). The DBA originated from the AA in 73 % of cases (190/260), and showed a straight course parallel to the AA in 93 % (177/190). PCHA aneurysm prevalence in elite volleyball players is high and associated with a specific branching type: a PCHA that originates from the axillary artery. Radiologists should have a high index of suspicion for this vascular overuse injury. For the first time vessel characteristics and reference values are described to facilitate ultrasound assessment. • Prevalence of PCHA aneurysms is 4.6 % among elite volleyball players. • All aneurysms are in proximal PCHA that originates directly from AA. • Vessel characteristics and reference values are described to facilitate US assessment. • Mean PCHA and DBA diameters can be used as reference values. • Radiologists need a high index of suspicion for this vascular overuse injury.

Conclusions and Recommendations Regarding the Deep Sea Hybrid Power Systems Initial Study

DTIC Science & Technology

2010-06-01

proton-exchange membrane fuel cells ( PEMFC ) powered with hydrogen and oxygen, similar to that used on proven subsurface vessels; (2) fuel-cells...AND STORAGE OPTIONS CONSIDERED FOR INITIAL STUDY NO. NOMENCLATURE DESCRIPTION 1 PWR Nuclear Reactor + Battery 2 FC1 PEMFC + Line for surface O2...Wellhead Gas + Reformer + Battery 3 FC2 PEMFC + Stored O2 + Wellhead Gas + Reformer + Battery 4 SV1 PEMFC + Submersible Vehicle for O2 Transport

Anatomical variations within the deep posterior compartment of the leg and important clinical consequences.

PubMed

Hislop, M; Tierney, P

2004-09-01

The management of musculoskeletal conditions makes up a large part of a sports medicine practitioner's practice. A thorough knowledge of anatomy is an essential component of the armament necessary to decipher the large number of potential conditions that may confront these practitioners. To cloud the issue further, anatomical variations may be present, such as supernumerary muscles, thickened fascial bands or variant courses of nerves and blood vessels, which can themselves manifest as acute or chronic conditions that lead to significant morbidity or limitation of activity. There are a number of contentious areas within the literature surrounding the anatomy of the leg, particularly involving the deep posterior compartment. Conditions such as chronic exertional compartment syndrome, tibial periostitis (shin splints), peripheral nerve entrapment and tarsal tunnel syndrome may all be affected by subtle anatomical variations. This paper primarily focuses on the deep posterior compartment of the leg and uses the gross dissection of cadaveric specimens to describe definitively the anatomy of the deep posterior compartment. Variant fascial attachments of flexor digitorum longus are documented and potential clinical sequelae such as chronic exertional compartment syndrome and tarsal tunnel syndrome are discussed.

Fire Safety Tests for Spherical Resorcinol Formaldehyde Resin: Data Summary Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kim, Dong-Sang; Peterson, Reid A.; Schweiger, Michael J.

2012-07-30

A draft safety evaluation of the scenario for spherical resorcinol-formaldehyde (SRF) resin fire inside the ion exchange column was performed by the Hanford Tank Waste Treatment and Immobilization Plant (WTP) Fire Safety organization. The result of this draft evaluation suggested a potential change of the fire safety classification for the Cesium Ion Exchange Process System (CXP) emergency elution vessels, equipment, and piping, which may be overly bounding based on the fire performance data from the manufacturer of the ion exchange resin selected for use at the WTP. To resolve this question, the fire properties of the SRF resin were measuredmore » by Southwest Research Institute (SwRI), following the American Society for Testing and Materials (ASTM) standard procedures, through a subcontract managed by Pacific Northwest National Laboratory (PNNL). For some tests, the ASTM standard procedures were not entirely appropriate or practical for the SRF resin material, so the procedures were modified and deviations from the ASTM standard procedures were noted. This report summarizes the results of fire safety tests performed and reported by SwRI. The efforts by PNNL were limited to summarizing the test results provided by SwRI into one consolidated data report. All as-received SwRI reports are attached to this report in the Appendix. Where applicable, the precision and bias of each test method, as given by each ASTM standard procedure, are included and compared with the SwRI test results of the SRF resin.« less

Cultural values embodying universal norms: a critique of a popular assumption about cultures and human rights.

PubMed

Jing-Bao, Nie

2005-09-01

In Western and non-Western societies, it is a widely held belief that the concept of human rights is, by and large, a Western cultural norm, often at odds with non-Western cultures and, therefore, not applicable in non-Western societies. The Universal Draft Declaration on Bioethics and Human Rights reflects this deep-rooted and popular assumption. By using Chinese culture(s) as an illustration, this article points out the problems of this widespread misconception and stereotypical view of cultures and human rights. It highlights the often ignored positive elements in Chinese cultures that promote and embody universal human values such as human dignity and human rights. It concludes, accordingly, with concrete suggestions on how to modify the Declaration.

The use of player physical and technical skill match activity profiles to predict position in the Australian Football League draft.

PubMed

Woods, Carl T; Veale, James P; Collier, Neil; Robertson, Sam

2017-02-01

This study investigated the extent to which position in the Australian Football League (AFL) national draft is associated with individual game performance metrics. Physical/technical skill performance metrics were collated from all participants in the 2014 national under 18 (U18) championships (18 games) drafted into the AFL (n = 65; 17.8 ± 0.5 y); 232 observations. Players were subdivided into draft position (ranked 1-65) and then draft round (1-4). Here, earlier draft selection (i.e., closer to 1) reflects a more desirable player. Microtechnology and a commercial provider facilitated the quantification of individual game performance metrics (n = 16). Linear mixed models were fitted to data, modelling the extent to which draft position was associated with these metrics. Draft position in the first/second round was negatively associated with "contested possessions" and "contested marks", respectively. Physical performance metrics were positively associated with draft position in these rounds. Correlations weakened for the third/fourth rounds. Contested possessions/marks were associated with an earlier draft selection. Physical performance metrics were associated with a later draft selection. Recruiters change the type of U18 player they draft as the selection pool reduces. juniors with contested skill appear prioritised.

Comments from the Developmental Neurotoxicology Committee of the Japanese Teratology Society on the OECD Guideline for the Testing of Chemicals, Proposal for a New Guideline 426, Developmental Neurotoxicity Study, Draft Document (October 2006 version), and on the Draft Document of the Retrospective Performance Assessment of the Draft Test Guideline 426 on Developmental Neurotoxicity.

PubMed

Ema, Makoto; Fukui, Yoshihiro; Aoyama, Hiroaki; Fujiwara, Michio; Fuji, Junichiro; Inouye, Minoru; Iwase, Takayuki; Kihara, Takahide; Oi, Akihide; Otani, Hiroki; Shinomiya, Mitsuhiro; Sugioka, Kozo; Yamano, Tsunekazu; Yamashita, Keisuke H; Tanimura, Takashi

2007-06-01

In October 2006, a new revision of the draft guideline (OECD Guideline for the Testing of Chemicals, Proposal for a New Guideline 426. Developmental Neurotoxicity Study) and Draft Document of the Retrospective Performance Assessment (RPA) of the Draft Test Guideline 426 on Developmental Neurotoxicity were distributed following incorporation of the results of the Expert Consultation Meeting in Tokyo on May 24-26, 2005. The draft guideline consists of 50 paragraphs and an appendix with 102 references; and the draft RPA consists of 37 paragraphs with 109 references. National coordinators were requested to arrange for national expert reviews of these draft documents in their member countries. Members of the Developmental Neurotoxicology (DNT) Committee of the Japanese Teratology Society (JTS) reviewed, discussed, and commented on the draft Test Guideline Proposal. The DNT Committee of the JTS also commented on the draft document of the RPA. These comments were sent to the OECD Secretariat. The DNT Committee of the JTS expects the comments to be useful for the finalization of these draft documents.

10 CFR 51.86 - Distribution of draft environmental impact statement.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 2 2013-01-01 2013-01-01 false Distribution of draft environmental impact statement. 51...-Regulations Implementing Section 102(2) Draft Environmental Impact Statements-Rulemaking § 51.86 Distribution of draft environmental impact statement. Copies of the draft environmental impact statement and any...

10 CFR 51.86 - Distribution of draft environmental impact statement.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 10 Energy 2 2012-01-01 2012-01-01 false Distribution of draft environmental impact statement. 51...-Regulations Implementing Section 102(2) Draft Environmental Impact Statements-Rulemaking § 51.86 Distribution of draft environmental impact statement. Copies of the draft environmental impact statement and any...

10 CFR 51.81 - Distribution of draft environmental impact statement.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 2 2011-01-01 2011-01-01 false Distribution of draft environmental impact statement. 51...-Regulations Implementing Section 102(2) Draft Environmental Impact Statements-Materials Licenses § 51.81 Distribution of draft environmental impact statement. Copies of the draft environmental impact statement and...