Comparative genomics of defense systems in archaea and bacteria
Makarova, Kira S.; Wolf, Yuri I.; Koonin, Eugene V.
2013-01-01
Our knowledge of prokaryotic defense systems has vastly expanded as the result of comparative genomic analysis, followed by experimental validation. This expansion is both quantitative, including the discovery of diverse new examples of known types of defense systems, such as restriction-modification or toxin-antitoxin systems, and qualitative, including the discovery of fundamentally new defense mechanisms, such as the CRISPR-Cas immunity system. Large-scale statistical analysis reveals that the distribution of different defense systems in bacterial and archaeal taxa is non-uniform, with four groups of organisms distinguishable with respect to the overall abundance and the balance between specific types of defense systems. The genes encoding defense system components in bacterial and archaea typically cluster in defense islands. In addition to genes encoding known defense systems, these islands contain numerous uncharacterized genes, which are candidates for new types of defense systems. The tight association of the genes encoding immunity systems and dormancy- or cell death-inducing defense systems in prokaryotic genomes suggests that these two major types of defense are functionally coupled, providing for effective protection at the population level. PMID:23470997
Systematic discovery of antiphage defense systems in the microbial pangenome.
Doron, Shany; Melamed, Sarah; Ofir, Gal; Leavitt, Azita; Lopatina, Anna; Keren, Mai; Amitai, Gil; Sorek, Rotem
2018-03-02
The arms race between bacteria and phages led to the development of sophisticated antiphage defense systems, including CRISPR-Cas and restriction-modification systems. Evidence suggests that known and unknown defense systems are located in "defense islands" in microbial genomes. Here, we comprehensively characterized the bacterial defensive arsenal by examining gene families that are clustered next to known defense genes in prokaryotic genomes. Candidate defense systems were systematically engineered and validated in model bacteria for their antiphage activities. We report nine previously unknown antiphage systems and one antiplasmid system that are widespread in microbes and strongly protect against foreign invaders. These include systems that adopted components of the bacterial flagella and condensin complexes. Our data also suggest a common, ancient ancestry of innate immunity components shared between animals, plants, and bacteria. Copyright © 2018 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works.
Evolutionary Genomics of Defense Systems in Archaea and Bacteria*
Koonin, Eugene V.; Makarova, Kira S.; Wolf, Yuri I.
2018-01-01
Evolution of bacteria and archaea involves an incessant arms race against an enormous diversity of genetic parasites. Accordingly, a substantial fraction of the genes in most bacteria and archaea are dedicated to antiparasite defense. The functions of these defense systems follow several distinct strategies, including innate immunity; adaptive immunity; and dormancy induction, or programmed cell death. Recent comparative genomic studies taking advantage of the expanding database of microbial genomes and metagenomes, combined with direct experiments, resulted in the discovery of several previously unknown defense systems, including innate immunity centered on Argonaute proteins, bacteriophage exclusion, and new types of CRISPR-Cas systems of adaptive immunity. Some general principles of function and evolution of defense systems are starting to crystallize, in particular, extensive gain and loss of defense genes during the evolution of prokaryotes; formation of genomic defense islands; evolutionary connections between mobile genetic elements and defense, whereby genes of mobile elements are repeatedly recruited for defense functions; the partially selfish and addictive behavior of the defense systems; and coupling between immunity and dormancy induction/programmed cell death. PMID:28657885
Prophage-mediated defense against viral attack and viral counter-defense
Dedrick, Rebekah M.; Jacobs-Sera, Deborah; Guerrero Bustamante, Carlos A.; Garlena, Rebecca A.; Mavrich, Travis N.; Pope, Welkin H.; Reyes, Juan C Cervantes; Russell, Daniel A.; Adair, Tamarah; Alvey, Richard; Bonilla, J. Alfred; Bricker, Jerald S.; Brown, Bryony R.; Byrnes, Deanna; Cresawn, Steven G.; Davis, William B.; Dickson, Leon A.; Edgington, Nicholas P.; Findley, Ann M.; Golebiewska, Urszula; Grose, Julianne H.; Hayes, Cory F.; Hughes, Lee E.; Hutchison, Keith W.; Isern, Sharon; Johnson, Allison A.; Kenna, Margaret A.; Klyczek, Karen K.; Mageeney, Catherine M.; Michael, Scott F.; Molloy, Sally D.; Montgomery, Matthew T.; Neitzel, James; Page, Shallee T.; Pizzorno, Marie C.; Poxleitner, Marianne K.; Rinehart, Claire A.; Robinson, Courtney J.; Rubin, Michael R.; Teyim, Joseph N.; Vazquez, Edwin; Ware, Vassie C.; Washington, Jacqueline; Hatfull, Graham F.
2017-01-01
Temperate phages are common and prophages are abundant residents of sequenced bacterial genomes. Mycobacteriophages are viruses infecting mycobacterial hosts including Mycobacterium tuberculosis and Mycobacterium smegmatis, encompass substantial genetic diversity, and are commonly temperate. Characterization of ten Cluster N temperate mycobacteriophages reveals at least five distinct prophage-expressed viral defense systems that interfere with infection of lytic and temperate phages that are either closely-related (homotypic defense) or unrelated (heterotypic defense). Target specificity is unpredictable, ranging from a single target phage to one-third of those tested. The defense systems include a single-subunit restriction system, a heterotypic exclusion system, and a predicted (p)ppGpp synthetase, which blocks lytic phage growth, promotes bacterial survival, and enables efficient lysogeny. The predicted (p)ppGpp synthetase coded by the Phrann prophage defends against phage Tweety infection, but Tweety codes for a tetrapeptide repeat protein, gp54, that acts as a highly effective counter-defense system. Prophage-mediated viral defense offers an efficient mechanism for bacterial success in host-virus dynamics, and counter-defense promotes phage co-evolution. PMID:28067906
Strategic Defense Initiative: Splendid Defense or Pipe Dream? Headline Series No. 275.
ERIC Educational Resources Information Center
Armstrong, Scott; Grier, Peter
This pamphlet presents a discussion of the various components of President Reagan's Strategic Defense Initiative (SDI) including the problem of pulling together various new technologies into an effective defensive system and the politics of the so-called "star wars" system. An important part of the defense initiative is the…
78 FR 35262 - Detection and Avoidance of Counterfeit Electronic Parts
Federal Register 2010, 2011, 2012, 2013, 2014
2013-06-12
... DEPARTMENT OF DEFENSE Defense Acquisition Regulations System [DFARS Case 2012-D055] Detection and Avoidance of Counterfeit Electronic Parts AGENCY: Defense Acquisition Regulations System, Department of... detection and avoidance coverage proposed to be included in the Defense Federal Acquisition Regulation...
32 CFR 637.20 - Security surveillance systems.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 32 National Defense 4 2011-07-01 2011-07-01 false Security surveillance systems. 637.20 Section 637.20 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY (CONTINUED) LAW... surveillance systems. Closed circuit video recording systems, to include those with an audio capability, may be...
32 CFR 637.20 - Security surveillance systems.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 32 National Defense 4 2012-07-01 2011-07-01 true Security surveillance systems. 637.20 Section 637.20 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY (CONTINUED) LAW... surveillance systems. Closed circuit video recording systems, to include those with an audio capability, may be...
32 CFR 637.20 - Security surveillance systems.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 32 National Defense 4 2014-07-01 2013-07-01 true Security surveillance systems. 637.20 Section 637.20 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY (CONTINUED) LAW... surveillance systems. Closed circuit video recording systems, to include those with an audio capability, may be...
32 CFR 637.20 - Security surveillance systems.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 32 National Defense 4 2013-07-01 2013-07-01 false Security surveillance systems. 637.20 Section 637.20 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY (CONTINUED) LAW... surveillance systems. Closed circuit video recording systems, to include those with an audio capability, may be...
Detection technique of targets for missile defense system
NASA Astrophysics Data System (ADS)
Guo, Hua-ling; Deng, Jia-hao; Cai, Ke-rong
2009-11-01
Ballistic missile defense system (BMDS) is a weapon system for intercepting enemy ballistic missiles. It includes ballistic-missile warning system, target discrimination system, anti-ballistic-missile guidance systems, and command-control communication system. Infrared imaging detection and laser imaging detection are widely used in BMDS for surveillance, target detection, target tracking, and target discrimination. Based on a comprehensive review of the application of target-detection techniques in the missile defense system, including infrared focal plane arrays (IRFPA), ground-based radar detection technology, 3-dimensional imaging laser radar with a photon counting avalanche photodiode (APD) arrays and microchip laser, this paper focuses on the infrared and laser imaging detection techniques in missile defense system, as well as the trends for their future development.
Defense Primer: The National Defense Budget Function (050)
2017-03-17
in parenthesis). This defense primer addresses the National Defense Budget (050), which is frequently used to explain trends in military spending...but which also includes some activities not conducted by the Department of Defense. What Is the Purpose of the Budget Function System? The budget
77 FR 19266 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2012-03-30
... DEPARTMENT OF DEFENSE Office of the Secretary [Docket ID: DOD-2012-OS-0040] Privacy Act of 1974; System of Records AGENCY: Office of the Secretary of Defense, DoD. ACTION: Notice to alter a system of... Department of Defense (DoD) civilian employees including Foreign Nationals, retired personnel, former DoD...
75 FR 58368 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2010-09-24
... DEPARTMENT OF DEFENSE Office of the Secretary [Docket ID DOD-2010-OS-0125] Privacy Act of 1974... Register Liaison Officer, Department of Defense. ZDO-001 System name: Accountability Records/Recall Rosters... commissaries, including Department of Defense (DoD) Federal employees, military service personnel not assigned...
76 FR 20336 - Defense Audit Advisory Committee (DAAC)
Federal Register 2010, 2011, 2012, 2013, 2014
2011-04-12
... DEPARTMENT OF DEFENSE Office of the Secretary Defense Audit Advisory Committee (DAAC) AGENCY... following Federal advisory committee meeting of the Defense Audit Advisory Committee will be held. DATES... management to include financial reporting processes, systems of internal controls, audit processes, and...
77 FR 74834 - Office of the Secretary
Federal Register 2010, 2011, 2012, 2013, 2014
2012-12-18
... DEPARTMENT OF DEFENSE Office of the Secretary Defense Audit Advisory Committee (DAAC); Notice of... Defense announces the following Federal advisory committee meeting of the Defense Audit Advisory Committee... financial management to include financial reporting processes, systems of internal controls, audit processes...
Influence of IR sensor technology on the military and civil defense
NASA Astrophysics Data System (ADS)
Becker, Latika
2006-02-01
Advances in basic infrared science and developments in pertinent technology applications have led to mature designs being incorporated in civil as well as military area defense systems. Military systems include both tactical and strategic, and civil area defense includes homeland security. Technical challenges arise in applying infrared sensor technology to detect and track targets for space and missile defense. Infrared sensors are valuable due to their passive capability, lower mass and power consumption, and their usefulness in all phases of missile defense engagements. Nanotechnology holds significant promise in the near future by offering unique material and physical properties to infrared components. This technology is rapidly developing. This presentation will review the current IR sensor technology, its applications, and future developments that will have an influence in military and civil defense applications.
75 FR 22562 - Privacy Act of 1974; Systems of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2010-04-29
... DEPARTMENT OF DEFENSE Office of the Secretary [Docket ID: DOD-2010-OS-0057] Privacy Act of 1974... Federal Register Liaison Officer, Department of Defense. S335.01 System name: Training and Employee... training funded or sponsored by the Defense Logistics Agency (DLA) to include DLA employees, Department of...
1989-08-01
Include in this plan the role of the Defense Technical Information Center (DTIC), the Defense Technology Security Administration ( DTSA ), and ODDR&E’s...DTIC = Defense Technical Information Center DTSA = Defense Technology Security Administration DUSD = Deputy Under Secretary of Defense Gloss. 2 DUSD...technologically sensitive requests. The Defense Technology Security Administi ation ( DTSA ) is developing a large system to track foreign military sales
... tract. Rheumatoid arthritis happens when the body’s own defense system doesn’t work properly. It affects joints ... conditions. These include: Lupus happens when the body’s defense system harms the joints, heart, skin, kidneys, and ...
2016-06-01
of and replace. DOD maintains weapon systems (e.g., aircraft and ships) and equipment (e.g., generators and radars) that require regular and...including helicopters, combat vehicles, air defense systems, ships, fighter and bomber aircraft , intercontinental ballistic missiles, jet aircraft ...Defense for Acquisition, Technology, and Logistics. 19In the depot maintenance context, an end item can be a weapon system, such as an aircraft , ship
Report to Congress on the Strategic Defense Initiative, 1992
1992-07-01
1.4.3 Shared View on Defenses .............................................................. 1-6 1.5 U.S. Contribution to a Global Defense System...including, in our view , that such defenses would not threaten existing deterrents--and the willingness of the U.S. to extend protection to allies...representing the central government as well as several Republics, the presentation was positively received. 1.4.3 Shared View on Defenses President
48 CFR 204.604 - Responsibilities.
Code of Federal Regulations, 2010 CFR
2010-10-01
... Section 204.604 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE GENERAL ADMINISTRATIVE MATTERS Contract Reporting 204.604 Responsibilities. (1) The... in the associated Government contract file instead of including a paper copy of the electronically...
48 CFR 204.604 - Responsibilities.
Code of Federal Regulations, 2013 CFR
2013-10-01
... Section 204.604 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE GENERAL ADMINISTRATIVE MATTERS Contract Reporting 204.604 Responsibilities. (1) The... in the associated Government contract file instead of including a paper copy of the electronically...
48 CFR 204.604 - Responsibilities.
Code of Federal Regulations, 2014 CFR
2014-10-01
... Section 204.604 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE GENERAL ADMINISTRATIVE MATTERS Contract Reporting 204.604 Responsibilities. (1) The... in the associated Government contract file instead of including a paper copy of the electronically...
48 CFR 204.604 - Responsibilities.
Code of Federal Regulations, 2011 CFR
2011-10-01
... Section 204.604 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE GENERAL ADMINISTRATIVE MATTERS Contract Reporting 204.604 Responsibilities. (1) The... in the associated Government contract file instead of including a paper copy of the electronically...
48 CFR 204.604 - Responsibilities.
Code of Federal Regulations, 2012 CFR
2012-10-01
... Section 204.604 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE GENERAL ADMINISTRATIVE MATTERS Contract Reporting 204.604 Responsibilities. (1) The... in the associated Government contract file instead of including a paper copy of the electronically...
Acquisition streamlining: A cultural change
NASA Technical Reports Server (NTRS)
Stewart, Jesse
1992-01-01
The topics are presented in viewgraph form and include the following: the defense systems management college, educational philosophy, the defense acquisition environment, streamlining initiatives, organizational streamlining types, defense law review, law review purpose, law review objectives, the Public Law Pilot Program, and cultural change.
Human Computer Interface Design Criteria. Volume 1. User Interface Requirements
2010-03-19
Television tuners, including tuner cards for use in computers, shall be equipped with secondary audio program playback circuitry. (c) All training...Shelf CSS Cascading Style Sheets DII Defense Information Infrastructure DISA Defense Information Systems Agency DoD Department of Defense
Federal Register 2010, 2011, 2012, 2013, 2014
2010-04-13
... transfer of defense articles, including technical data, and defense services for the manufacture of Small Diameter Bomb Increment I (SDB I) Weapon System in Italy for end-use by the Italian Air Force. The United...
Code of Federal Regulations, 2010 CFR
2016-10-01
... 48 Federal Acquisition Regulations System 3 2016-10-01 2016-10-01 false Content. 206.303-2 Section 206.303-2 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE ACQUISITION PLANNING COMPETITION REQUIREMENTS Other Than Full and Open Competition 206.303-2 Content. (b)(i) Include the information...
78 FR 14283 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2013-03-05
... Defense. S500.55 System name: Information Technology Access and Control Records (December 2, 2008, 73 FR... without change, including any personal identifiers or contact information. FOR FURTHER INFORMATION CONTACT.... SUPPLEMENTARY INFORMATION: The Defense Logistics Agency's system of record subject to the Privacy Act of 1974 (5...
Confinement of Radioactive Materials at Defense Nuclear Facilities
2004-10-01
The design of defense nuclear facilities includes systems whose reliable operation is vital to the protection of the public, workers, and the...final safety-class barrier to the release of hazardous materials with potentially serious public consequences. The Defense Nuclear Facilities Safety...the public at certain defense nuclear facilities . This change has resulted in downgrading of the functional safety classification of confinement
Defense satellite communications - Present and future in the United States and Australia
NASA Astrophysics Data System (ADS)
Mixon, M. S.
A new U.S. DOD Defense Space Policy directive signed in March, 1987 emphasizes the role of C3I satellites in future efforts to enhance military force management. Satellites of this type that are currently in use include FltSatCom, Leasat, and DSCS II and III. Future U.S. systems figuring in the Pacific Defense Satellite System, in which Australia participates, will include the 'UHF Follow-On', and the Milstar next-generation satellite for high priority messages during crises. Australian participation will begin with a single channel on the Aussat I satellite.
32 CFR 1602.21 - Selective Service Law.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 32 National Defense 6 2011-07-01 2011-07-01 false Selective Service Law. 1602.21 Section 1602.21 National Defense Other Regulations Relating to National Defense SELECTIVE SERVICE SYSTEM DEFINITIONS § 1602.21 Selective Service Law. The term Selective Service Law includes the Military Selective Service Act...
USDA-ARS?s Scientific Manuscript database
Crop losses due to pathogens are a major threat to global food security. Plants employ a multilayer defense system against pathogens including use of physical barriers (cell wall), induction of hypersensitive defense response (HR), resistance (R) proteins, and synthesis of antimicrobial peptides (AM...
32 CFR 1602.17 - Military service.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 32 National Defense 6 2010-07-01 2010-07-01 false Military service. 1602.17 Section 1602.17 National Defense Other Regulations Relating to National Defense SELECTIVE SERVICE SYSTEM DEFINITIONS § 1602.17 Military service. The term military service includes service in the Army, the Navy, the Air Force...
Biological and chemical terrorism scenarios and implications for detection systems needs
NASA Astrophysics Data System (ADS)
Gordon, Susanna P.; Chumfong, Isabelle; Edwards, Donna M.; Gleason, Nathaniel J.; West, Todd; Yang, Lynn
2007-04-01
Terrorists intent on causing many deaths and severe disruption to our society could, in theory, cause hundreds to tens of thousands of deaths and significant contamination of key urban facilities by using chemical or biological (CB) agents. The attacks that have occurred to date, such as the 1995 Aum Shinrikyo CB attacks and the 2001 anthrax letters, have been very small on the scale of what is possible. In order to defend against and mitigate the impacts of large-scale terrorist attacks, defensive systems for protection of urban areas and high-value facilities from biological and chemical threats have been deployed. This paper reviews analyses of such scenarios and of the efficacy of potential response options, discusses defensive systems that have been deployed and detectors that are being developed, and finally outlines the detection systems that will be needed for improved CB defense in the future. Sandia's collaboration with San Francisco International Airport on CB defense will also be briefly reviewed, including an overview of airport facility defense guidelines produced in collaboration with Lawrence Berkeley National Laboratory. The analyses that will be discussed were conducted by Sandia National Laboratories' Systems Studies Department in support of the U.S. Department of Homeland Security (DHS) Science and Technology Directorate, and include quantitative analyses utilizing simulation models developed through close collaboration with subject matter experts, such as public health officials in urban areas and biological defense experts.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 32 National Defense 6 2010-07-01 2010-07-01 false State. 1602.23 Section 1602.23 National Defense Other Regulations Relating to National Defense SELECTIVE SERVICE SYSTEM DEFINITIONS § 1602.23 State. The word State includes, where applicable, the several States of the United States, the City of New York...
Defense Health Care: DOD Chiropractor Wage Rates
2013-03-14
Page 2 Introduction • In 2000, Congress mandated that the Department of Defense (DOD) develop a plan to provide chiropractic care as a permanent...part of the Defense Health Program. • Prior to the establishment of DOD’s chiropractic program, Congress directed DOD to conduct demonstration...projects to evaluate the feasibility and advisability of expanding DOD’s health system to include chiropractic care. • The National Defense
Rethinking Import and Export Controls for Defense-Related Goods
2013-05-01
restrictions were imposed on the basis of country (Trading with the Enemy Act) or product (Neutrality Act). However, in the post-war environment, a more mixed...described below. • Arms Export Control Act (AECA) of 1976—grants the President the power to control the export of defense products and services. The act...defense-related items and services. The products regulated include weapons systems (e.g., aircraft, tanks, etc.) but also include subsystems or
48 CFR 252.247-7008 - Evaluation of bids.
Code of Federal Regulations, 2010 CFR
2010-10-01
....247-7008 Section 252.247-7008 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CLAUSES AND FORMS SOLICITATION PROVISIONS AND CONTRACT CLAUSES Text of... accomplishment of any item in the bid schedule, the Offeror shall include in the unit price any costs for bridge...
48 CFR 252.247-7008 - Evaluation of bids.
Code of Federal Regulations, 2011 CFR
2011-10-01
....247-7008 Section 252.247-7008 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CLAUSES AND FORMS SOLICITATION PROVISIONS AND CONTRACT CLAUSES Text of... accomplishment of any item in the bid schedule, the Offeror shall include in the unit price any costs for bridge...
48 CFR 252.247-7008 - Evaluation of bids.
Code of Federal Regulations, 2013 CFR
2013-10-01
....247-7008 Section 252.247-7008 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CLAUSES AND FORMS SOLICITATION PROVISIONS AND CONTRACT CLAUSES Text of... accomplishment of any item in the bid schedule, the Offeror shall include in the unit price any costs for bridge...
48 CFR 252.247-7008 - Evaluation of bids.
Code of Federal Regulations, 2012 CFR
2012-10-01
....247-7008 Section 252.247-7008 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CLAUSES AND FORMS SOLICITATION PROVISIONS AND CONTRACT CLAUSES Text of... accomplishment of any item in the bid schedule, the Offeror shall include in the unit price any costs for bridge...
48 CFR 232.503-15 - Application of Government title terms.
Code of Federal Regulations, 2012 CFR
2012-10-01
... title terms. 232.503-15 Section 232.503-15 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE GENERAL CONTRACTING REQUIREMENTS CONTRACT FINANCING Progress... took place in the prior month; and (iii) The summary report includes as a minimum, the total number and...
48 CFR 232.503-15 - Application of Government title terms.
Code of Federal Regulations, 2014 CFR
2014-10-01
... title terms. 232.503-15 Section 232.503-15 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE GENERAL CONTRACTING REQUIREMENTS CONTRACT FINANCING Progress... took place in the prior month; and (iii) The summary report includes as a minimum, the total number and...
48 CFR 232.503-15 - Application of Government title terms.
Code of Federal Regulations, 2013 CFR
2013-10-01
... title terms. 232.503-15 Section 232.503-15 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE GENERAL CONTRACTING REQUIREMENTS CONTRACT FINANCING Progress... took place in the prior month; and (iii) The summary report includes as a minimum, the total number and...
48 CFR 232.503-15 - Application of Government title terms.
Code of Federal Regulations, 2010 CFR
2010-10-01
... title terms. 232.503-15 Section 232.503-15 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE GENERAL CONTRACTING REQUIREMENTS CONTRACT FINANCING Progress... place in the prior month; and (iii) The summary report includes as a minimum, the total number and...
48 CFR 232.503-15 - Application of Government title terms.
Code of Federal Regulations, 2011 CFR
2011-10-01
... title terms. 232.503-15 Section 232.503-15 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE GENERAL CONTRACTING REQUIREMENTS CONTRACT FINANCING Progress... place in the prior month; and (iii) The summary report includes as a minimum, the total number and...
NASA Astrophysics Data System (ADS)
Jannson, Tomasz; Kostrzewski, Andrew; Patton, Edward; Pradhan, Ranjit; Shih, Min-Yi; Walter, Kevin; Savant, Gajendra; Shie, Rick; Forrester, Thomas
2010-04-01
In this paper, Bayesian inference is applied to performance metrics definition of the important class of recent Homeland Security and defense systems called binary sensors, including both (internal) system performance and (external) CONOPS. The medical analogy is used to define the PPV (Positive Predictive Value), the basic Bayesian metrics parameter of the binary sensors. Also, Small System Integration (SSI) is discussed in the context of recent Homeland Security and defense applications, emphasizing a highly multi-technological approach, within the broad range of clusters ("nexus") of electronics, optics, X-ray physics, γ-ray physics, and other disciplines.
75 FR 65007 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2010-10-21
... DEPARTMENT OF DEFENSE Department of the Air Force [Docket ID: USAF-2010-0027] Privacy Act of 1974... Special Investigations (AFOSI). Also includes AFOSI personnel assigned to any Department of Defense (DoD... therein may be specifically disclosed outside the Department of Defense as a routine use pursuant to 5 U.S...
2016-07-01
etc., and all of the IRL1n rather than a technology-centric approach that included TR L1 with all its interfaces. The inter- face -centric approach...Acquisition Research Journal , 23(3), In Print. The average of the SRL vector, equation (4), describes how mature the sys- tem is. The Sauser approach...Application of System and Integration Readiness Levels to Department of Defense Research and Development. Defense Acquisition Research Journal , 23(3), In
ERIC Educational Resources Information Center
Defense Civil Preparedness Agency (DOD), Battle Creek, MI.
The need for, and a description of, emergency functions required to save lives and protect property in nuclear or natural disasters are presented. Topics discussed include: (1) The Civil Defense Warning System, (2) Introduction to the Emergency Operations Program, (3) Five subprograms of the Emergency Operations Program, (4) Emergency Operations…
A two-dimensional neuropsychology of defense: fear/anxiety and defensive distance.
McNaughton, Neil; Corr, Philip J
2004-05-01
We present in this paper a picture of the neural systems controlling defense that updates and simplifies Gray's "Neuropsychology of Anxiety". It is based on two behavioural dimensions: 'defensive distance' as defined by the Blanchards and 'defensive direction'. Defensive direction is a categorical dimension with avoidance of threat corresponding to fear and approach to threat corresponding to anxiety. These two psychological dimensions are mapped to underlying neural dimensions. Defensive distance is mapped to neural level, with the shortest defensive distances involving the lowest neural level (periaqueductal grey) and the largest defensive distances the highest neural level (prefrontal cortex). Defensive direction is mapped to separate parallel streams that run across these levels. A significant departure from prior models is the proposal that both fear and anxiety are represented at all levels. The theory is presented in a simplified form that does not incorporate the interactions that must occur between non-adjacent levels of the system. It also requires expansion to include the dimension of escapability of threat. Our current development and these proposed future extensions do not change the core concepts originally proposed by Gray and, we argue, demonstrate their enduring value.
Environmental Assessment Addressing Gate Complex Construction at Scott Air Force Base, Illinois
2014-04-01
2014 221,760 No change I3. Construct Aircraft Deicing Pad, which would include an underground storage tank, a drainage system , and permanent lighting...Defense Information System Agency DNL day-night average A-weighted sound level DOD Department of Defense DOPAA Description of the Proposed Action...MWDs); a truck-inspection search office; a cargo-transfer facility; a mobile vehicle and cargo inspection system ; an over watch building; and a
Koonin, Eugene V
2017-02-10
Complementarity between nucleic acid molecules is central to biological information transfer processes. Apart from the basal processes of replication, transcription and translation, complementarity is also employed by multiple defense and regulatory systems. All cellular life forms possess defense systems against viruses and mobile genetic elements, and in most of them some of the defense mechanisms involve small guide RNAs or DNAs that recognize parasite genomes and trigger their inactivation. The nucleic acid-guided defense systems include prokaryotic Argonaute (pAgo)-centered innate immunity and CRISPR-Cas adaptive immunity as well as diverse branches of RNA interference (RNAi) in eukaryotes. The archaeal pAgo machinery is the direct ancestor of eukaryotic RNAi that, however, acquired additional components, such as Dicer, and enormously diversified through multiple duplications. In contrast, eukaryotes lack any heritage of the CRISPR-Cas systems, conceivably, due to the cellular toxicity of some Cas proteins that would get activated as a result of operon disruption in eukaryotes. The adaptive immunity function in eukaryotes is taken over partly by the PIWI RNA branch of RNAi and partly by protein-based immunity. In this review, I briefly discuss the interplay between homology and analogy in the evolution of RNA- and DNA-guided immunity, and attempt to formulate some general evolutionary principles for this ancient class of defense systems. This article was reviewed by Mikhail Gelfand and Bojan Zagrovic.
Role of resveratrol in regulation of cellular defense systems against oxidative stress.
Truong, Van-Long; Jun, Mira; Jeong, Woo-Sik
2018-01-01
Resveratrol, a natural polyphenolic compound, is found in various kinds of fruits, plants, and their commercial products such as red wine. It has been demonstrated to exhibit a variety of health-promoting effects including prevention and/or treatment of cardiovascular diseases, inflammation, diabetes, neurodegeneration, aging, and cancer. Cellular defensive properties of resveratrol can be explained through its ability of either directly neutralizing reactive oxygen species/reactive nitrogen species (ROS/RNS) or indirectly upregulating the expression of cellular defensive genes. As a direct antioxidant agent, resveratrol scavenges diverse ROS/RNS as well as secondary organic radicals with mechanisms of hydrogen atom transfer and sequential proton loss electron transfer, thereby protecting cellular biomolecules from oxidative damage. Resveratrol also enhances the expression of various antioxidant defensive enzymes such as heme oxygenase 1, catalase, glutathione peroxidase, and superoxide dismutase as well as the induction of glutathione level responsible for maintaining the cellular redox balance. Such defenses could be achieved by regulating various signaling pathways including sirtuin 1, nuclear factor-erythroid 2-related factor 2 and nuclear factor κB. This review provides current understanding and information on the role of resveratrol in cellular defense system against oxidative stress. © 2017 BioFactors, 44(1):36-49, 2018. © 2017 International Union of Biochemistry and Molecular Biology.
Strategic Defense Initiative Organization adaptive structures program overview
NASA Astrophysics Data System (ADS)
Obal, Michael; Sater, Janet M.
In the currently envisioned architecture none of the Strategic Defense System (SDS) elements to be deployed will receive scheduled maintenance. Assessments of performance capability due to changes caused by the uncertain effects of environments will be difficult, at best. In addition, the system will have limited ability to adjust in order to maintain its required performance levels. The Materials and Structures Office of the Strategic Defense Initiative Organization (SDIO) has begun to address solutions to these potential difficulties via an adaptive structures technology program that combines health and environment monitoring with static and dynamic structural control. Conceivable system benefits include improved target tracking and hit-to-kill performance, on-orbit system health monitoring and reporting, and threat attack warning and assessment.
Induction of Systemic Resistance against Insect Herbivores in Plants by Beneficial Soil Microbes
Rashid, Md. Harun-Or; Chung, Young R.
2017-01-01
Soil microorganisms with growth-promoting activities in plants, including rhizobacteria and rhizofungi, can improve plant health in a variety of different ways. These beneficial microbes may confer broad-spectrum resistance to insect herbivores. Here, we provide evidence that beneficial microbes modulate plant defenses against insect herbivores. Beneficial soil microorganisms can regulate hormone signaling including the jasmonic acid, ethylene and salicylic acid pathways, thereby leading to gene expression, biosynthesis of secondary metabolites, plant defensive proteins and different enzymes and volatile compounds, that may induce defenses against leaf-chewing as well as phloem-feeding insects. In this review, we discuss how beneficial microbes trigger induced systemic resistance against insects by promoting plant growth and highlight changes in plant molecular mechanisms and biochemical profiles. PMID:29104585
Reconstruction of the evolution of microbial defense systems.
Puigbò, Pere; Makarova, Kira S; Kristensen, David M; Wolf, Yuri I; Koonin, Eugene V
2017-04-04
Evolution of bacterial and archaeal genomes is a highly dynamic process that involves intensive loss of genes as well as gene gain via horizontal transfer, with a lesser contribution from gene duplication. The rates of these processes can be estimated by comparing genomes that are linked by an evolutionary tree. These estimated rates of genome dynamics events substantially differ for different functional classes of genes. The genes involved in defense against viruses and other invading DNA are among those that are gained and lost at the highest rates. We employed a stochastic birth-and-death model to obtain maximum likelihood estimates of the rates of gain and loss of defense genes in 35 groups of closely related bacterial genomes and one group of archaeal genomes. We find that on average, the defense genes experience 1.4 fold higher flux than the rest of microbial genes. This excessive flux of defense genes over the genomic mean is consistent across diverse microbial groups. The few exceptions include intracellular parasites with small, degraded genomes that possess few defense systems which are more stable than in other microbes. Generally, defense genes follow the previously established pattern of genome dynamics, with gene family loss being about 3 times more common than gain and an order of magnitude more common than expansion or contraction of gene families. Case by case analysis of the evolutionary dynamics of defense genes indicates frequent multiple events in the same locus and widespread involvement of mobile elements in the gain and loss of defense genes. Evolution of microbial defense systems is highly dynamic but, notwithstanding the host-parasite arms race, generally follows the same trends that have been established for the rest of the genes. Apart from the paucity and the low flux of defense genes in parasitic bacteria with deteriorating genomes, there is no clear connection between the evolutionary regime of defense systems and microbial life style.
Defense Medical Human Resources System-internet (DMHRSi): A Case Study on Compliance and Accuracy
2009-06-02
including suggestions for reducing the burden, to Department of Defense, Washington Headquarters Services, Directorate for Information Operations ...military, contractor operated facilities. The hospital also houses the second oldest Family Practice Residency in the Army (DeWitt, 2008). The...collection and analysis of financial, workload, and personnel data within the organization. The MHS utilizes information managemen * systems like the
Local Area Defense (LAD) Demonstration
2004-09-01
Prozac ? Fentanyl? Institution, incident command, community drills - use of internet - digital photos of all victims to follow them through the system...and Budget, Paperwork Reduction Project (0704-0188), Washington, DC 20503 1. AGENCY USE ONLY 2. REPORT DATE 3. REPORT TYPE AND DATES COVERED (Leave...detection and rapid response system for local area defense using the University of Maryland Baltimore (UMB) Campus as a testbed. Additional goals includes
Chemical and biological warfare. Should defenses be researched and deployed?
Orient, J M
1989-08-04
The threat of chemical and biological weapons of mass destruction has intensified because of improved delivery systems and advances in chemistry, genetics, and other sciences. Possible US responses to this threat include deterrence, defenses, and/or disarmament, including a reaffirmation of the Biological and Toxin Weapons Convention of 1972, which is now in jeopardy. This article discusses the history of chemical and biological warfare, existing and potential weapons, the proliferation of weapons and delivery systems, ways to prevent the use of these weapons, and ways to protect populations from their effects.
Bacterial 'immunity' against bacteriophages.
Abedon, Stephen T
2012-01-01
Vertebrate animals possess multiple anti-pathogen defenses. Individual mechanisms usually are differentiated into those that are immunologically adaptive vs. more "primitive" anti-pathogen phenomena described as innate responses. Here I frame defenses used by bacteria against bacteriophages as analogous to these animal immune functions. Included are numerous anti-phage defenses in addition to the adaptive immunity associated with CRISPR/cas systems. As these other anti-pathogen mechanisms are non-adaptive they can be described as making up an innate bacterial immunity. This exercise was undertaken in light of the recent excitement over the discovery that CRISPR/cas systems can serve, as noted, as a form of bacterial adaptive immunity. The broader goal, however, is to gain novel insight into bacterial defenses against phages by fitting these mechanisms into considerations of how multicellular organisms also defend themselves against pathogens. This commentary can be viewed in addition as a bid toward integrating these numerous bacterial anti-phage defenses into a more unified immunology.
Multifaceted Defense against Listeria monocytogenes in the Gastro-Intestinal Lumen
Becattini, Simone; Pamer, Eric G.
2017-01-01
Listeria monocytogenes is a foodborne pathogen that can cause febrile gastroenteritis in healthy subjects and systemic infections in immunocompromised individuals. Despite the high prevalence of L. monocytogenes in the environment and frequent contamination of uncooked meat and poultry products, infections with this pathogen are relatively uncommon, suggesting that protective defenses in the general population are effective. In the mammalian gastrointestinal tract, a variety of defense mechanisms prevent L. monocytogenes growth, epithelial penetration and systemic dissemination. Among these defenses, colonization resistance mediated by the gut microbiota is crucial in protection against a range of intestinal pathogens, including L. monocytogenes. Here we review defined mechanisms of defense against L. monocytogenes in the lumen of the gastro-intestinal tract, with particular emphasis on protection conferred by the autochthonous microbiota. We suggest that selected probiotic species derived from the microbiota may be developed for eventual clinical use to enhance resistance against L. monocytogenes infections. PMID:29271903
75 FR 25212 - Federal Advisory Committee; Defense Audit Advisory Committee (DAAC)
Federal Register 2010, 2011, 2012, 2013, 2014
2010-05-07
..., through the Under Secretary of Defense (Comptroller)/Chief Financial Officer, independent advice and recommendations on DoD financial management to include financial reporting processes, systems of internal controls... CONTACT: The Committee's Designated Federal Officer (DFO) is Sandra Gregory, Office of the Under Secretary...
USDA-ARS?s Scientific Manuscript database
Brassicales contain a myrosinase enzyme that hydrolyzes glucosinolates to form toxic isothiocyanates, as a defense against bacteria, fungi, insects and herbivores including man. Low levels of isothiocyanates trigger a host defense system in mammals that protects them against chronic diseases. Becaus...
75 FR 48655 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2010-08-11
... DEPARTMENT OF DEFENSE Office of the Secretary [Docket ID: DOD-2010-OS-0112] Privacy Act of 1974... (DLA) to include DLA employees, Department of Defense military personnel, non-appropriated fund..., individual training plans, progress reports, and similar records used in intern, upward mobility, career...
The Missile Defense Agency's space tracking and surveillance system
NASA Astrophysics Data System (ADS)
Watson, John; Zondervan, Keith
2008-10-01
The Ballistic Missile Defense System (BMDS) is a layered system incorporating elements in space. In addition to missile warning systems at geosynchronous altitudes, an operational BMDS will include a low Earth orbit (LEO) system-the Space Tracking and Surveillance System (STSS). It will use infrared sensing technologies synergistically with the Space Based Infrared Systems (SBIRS) and will provide a seamless adjunct to radars and sensors on the ground and in airborne platforms. STSS is being designed for a future operational capability to defend against evolving threats. STSS development is divided into phases, commencing with a two-satellite demonstration constellation scheduled for launch in 2008. The demonstration satellites will conduct a menu of tests and experiments to prove the system concept, including the ground segment. They will have limited operational capability within the integrated BMDS. Data from the demonstration satellites will be received and processed by the Missile Defense Space Experiment Center (MDSEC), a part of the Missile Defense Integration and Operations Center (MDIOC). MDA launched in 2007 into LEO a satellite (NFIRE) designed to make near-field multispectral measurements of boosting targets and to demonstrate laser communication, the latter in conjunction with the German satellite TerraSAR-X. The gimbaled, lightweight laser terminal has demonstrated on orbit a 5.5 gbps rate in both directions. The filter passbands of NFIRE are similar to the STSS demonstrator track sensor. While providing useful phenomenology during its time on orbit, NFIRE will also serve as a pathfinder in the development of STSS operations procedures.
Våge, Selina; Storesund, Julia E; Giske, Jarl; Thingstad, T Frede
2014-01-01
Trophic mechanisms that can generate biodiversity in food webs include bottom-up (growth rate regulating) and top-down (biomass regulating) factors. The top-down control has traditionally been analyzed using the concepts of "Keystone Predation" (KP) and "Killing-the-Winner" (KtW), predominately occuring in discussions of macro- and micro-biological ecology, respectively. Here we combine the classical diamond-shaped food web structure frequently discussed in KP analyses and the KtW concept by introducing a defense strategist capable of partial defense. A formalized description of a trade-off between the defense-strategist's competitive and defensive ability is included. The analysis reveals a complex topology of the steady state solution with strong relationships between food web structure and the combination of trade-off, defense strategy and the system's nutrient content. Among the results is a difference in defense strategies corresponding to maximum biomass, production, or net growth rate of invading individuals. The analysis thus summons awareness that biomass or production, parameters typically measured in field studies to infer success of particular biota, are not directly acted upon by natural selection. Under coexistence with a competition specialist, a balance of competitive and defensive ability of the defense strategist was found to be evolutionarily stable, whereas stronger defense was optimal under increased nutrient levels in the absence of the pure competition specialist. The findings of success of different defense strategies are discussed with respect to SAR11, a highly successful bacterial clade in the pelagic ocean.
Implementation of a Data-Based Medical Event Reporting System in the U.S. Department of Defense
2005-05-01
where patient safety events warrant further investigation. Introduction Department of Defense Instruction 6025.17 established the Military Health ...Administration (VHA) Patient Safety Reporting Program for error tracking and reporting within all military health care facilities. 5 On August 16, 2001...DoD Instruction number 6025.17 “established a Military Health System Patient Safety Center (MHSPSC), including a MHS Patient Safety Registry (MHSPSR
10 CFR 217.2 - Priorities and allocations authority.
Code of Federal Regulations, 2012 CFR
2012-01-01
... 10 Energy 3 2012-01-01 2012-01-01 false Priorities and allocations authority. 217.2 Section 217.2 Energy DEPARTMENT OF ENERGY OIL ENERGY PRIORITIES AND ALLOCATIONS SYSTEM General § 217.2 Priorities and... Security with respect to essential civilian needs supporting national defense, including civil defense and...
10 CFR 217.2 - Priorities and allocations authority.
Code of Federal Regulations, 2014 CFR
2014-01-01
... 10 Energy 3 2014-01-01 2014-01-01 false Priorities and allocations authority. 217.2 Section 217.2 Energy DEPARTMENT OF ENERGY OIL ENERGY PRIORITIES AND ALLOCATIONS SYSTEM General § 217.2 Priorities and... Security with respect to essential civilian needs supporting national defense, including civil defense and...
Countering MANPADS: study of new concepts and applications: part two
NASA Astrophysics Data System (ADS)
Maltese, Dominique; Vergnolle, Jean-François; Aragones, Julien; Renaudat, Mathieu
2007-04-01
The latest events of ground-to-air Man Portable Air Defense (MANPAD) attacks against aircraft have revealed a new threat both for military and civilian aircraft. Consequently, the implementation of protecting systems (i.e. Directed Infra Red Counter Measure - DIRCM) in order to face IR guided missiles turns out to be now inevitable. In a near future, aircraft will have to possess detection, tracking, identification, targeting and jamming capabilities to face MANPAD threats. Besides, Multiple Missiles attacks become more and more current scenarios to deal with. In this paper, a practical example of DIRCM systems under study at SAGEM DEFENSE & SECURITY Company is presented. The article is the continuation of a previous SPIE one. Self-protection solutions include built-in and automatic locking-on, tracking, identification and laser jamming capabilities, including defeat assessment. Target Designations are provided by a Missile Warning System. Targets scenarios including multiple threats are considered to design systems architectures. In a first step, the article reminds the context, current and future threats (IR seekers of different generations...), and scenarios for system definition. Then, it focuses on potential self-protection systems under study at SAGEM DEFENSE & SECURITY Company. Different strategies including target identification, multi band laser and active imagery have been previously studied in order to design DIRCM System solutions. Thus, results of self-protection scenarios are provided for different MANPAD scenarios to highlight key problems to solve. Data have been obtained from simulation software modeling full DIRCM systems architectures on technical and operational scenarios (parametric studies).
Vertebrate defense against parasites: Interactions between avoidance, resistance, and tolerance.
Klemme, Ines; Karvonen, Anssi
2017-01-01
Hosts can utilize different types of defense against the effects of parasitism, including avoidance, resistance, and tolerance. Typically, there is tremendous heterogeneity among hosts in these defense mechanisms that may be rooted in the costs associated with defense and lead to trade-offs with other life-history traits. Trade-offs may also exist between the defense mechanisms, but the relationships between avoidance, resistance, and tolerance have rarely been studied. Here, we assessed these three defense traits under common garden conditions in a natural host-parasite system, the trematode eye-fluke Diplostomum pseudospathaceum and its second intermediate fish host. We looked at host individuals originating from four genetically distinct populations of two closely related salmonid species (Atlantic salmon, Salmo salar and sea trout, Salmo trutta trutta ) to estimate the magnitude of variation in these defense traits and the relationships among them. We show species-specific variation in resistance and tolerance and population-specific variation in resistance. Further, we demonstrate evidence for a trade-off between resistance and tolerance. Our results suggest that the variation in host defense can at least partly result from a compromise between different interacting defense traits, the relative importance of which is likely to be shaped by environmental components. Overall, this study emphasizes the importance of considering different components of the host defense system when making predictions on the outcome of host-parasite interactions.
Systemic bacterial infection and immune defense phenotypes in Drosophila melanogaster.
Khalil, Sarah; Jacobson, Eliana; Chambers, Moria C; Lazzaro, Brian P
2015-05-13
The fruit fly Drosophila melanogaster is one of the premier model organisms for studying the function and evolution of immune defense. Many aspects of innate immunity are conserved between insects and mammals, and since Drosophila can readily be genetically and experimentally manipulated, they are powerful for studying immune system function and the physiological consequences of disease. The procedure demonstrated here allows infection of flies by introduction of bacteria directly into the body cavity, bypassing epithelial barriers and more passive forms of defense and allowing focus on systemic infection. The procedure includes protocols for the measuring rates of host mortality, systemic pathogen load, and degree of induction of the host immune system. This infection procedure is inexpensive, robust and quantitatively repeatable, and can be used in studies of functional genetics, evolutionary life history, and physiology.
2002-09-01
including suggestions for reducing this burden, to Washington Headquarters Services , Directorate for Information Operations and Reports, 1215 Jefferson...require the acquisition of unfamiliar weapons and support systems. Joint and service visions of the military after next raise serious questions that...and the U.S. Defense Industry The U.S. military is awash in visions of transformation. There is an array of joint and service visions of what has become
Use of the Homeland-Defense Operational Planning System (HOPS) for Emergency Management
DOE Office of Scientific and Technical Information (OSTI.GOV)
Durling, Jr., R L; Price, D E
2005-12-16
The Homeland-Defense Operational Planning System (HOPS), is a new operational planning tool leveraging Lawrence Livermore National Laboratory's expertise in weapons systems and in sparse information analysis to support the defense of the U.S. homeland. HOPS provides planners with a basis to make decisions to protect against acts of terrorism, focusing on the defense of facilities critical to U.S. infrastructure. Criticality of facilities, structures, and systems is evaluated on a composite matrix of specific projected casualty, economic, and sociopolitical impact bins. Based on these criteria, significant unidentified vulnerabilities are identified and secured. To provide insight into potential successes by malevolent actors,more » HOPS analysts strive to base their efforts mainly on unclassified open-source data. However, more cooperation is needed between HOPS analysts and facility representatives to provide an advantage to those whose task is to defend these facilities. Evaluated facilities include: refineries, major ports, nuclear power plants and other nuclear licensees, dams, government installations, convention centers, sports stadiums, tourist venues, and public and freight transportation systems. A generalized summary of analyses of U.S. infrastructure facilities will be presented.« less
Risk Assessment Using The Homeland-Defense Operational Planning System (HOPS)
DOE Office of Scientific and Technical Information (OSTI.GOV)
Price, D E; Durling, R L
2005-10-10
The Homeland-Defense Operational Planning System (HOPS), is a new operational planning tool leveraging Lawrence Livermore National Laboratory's expertise in weapons systems and in sparse information analysis to support the defense of the U.S. homeland. HOPS provides planners with a basis to make decisions to protect against acts of terrorism, focusing on the defense of facilities critical to U.S. infrastructure. Criticality of facilities, structures, and systems is evaluated on a composite matrix of specific projected casualty, economic, and sociopolitical impact bins. Based on these criteria, significant unidentified vulnerabilities are identified and secured. To provide insight into potential successes by malevolent actors,more » HOPS analysts strive to base their efforts mainly on unclassified open-source data. However, more cooperation is needed between HOPS analysts and facility representatives to provide an advantage to those whose task is to defend these facilities. Evaluated facilities include: refineries, major ports, nuclear power plants and other nuclear licensees, dams, government installations, convention centers, sports stadiums, tourist venues, and public and freight transportation systems. A generalized summary of analyses of U.S. infrastructure facilities will be presented.« less
Defense Acquisition Reform: Where Do We Go From Here? A Compendium of Views by Leading Experts
2014-10-02
and government-owned production come close to matching the power of the Free Enterprise System broadly embraced by the U.S., including when providing...The defense acquisition process—along with most of our nation’s challenges, such as the provision of energy , building an economy, providing...Acquisition, Technology & Logistics. The projects have covered a wide variety of topics including, directed energy , unmanned vehicle, reviews of
ImmunoScenarios: A Game for the Immune System.
ERIC Educational Resources Information Center
Taylor, Mark F.; Jackson, Sally W.
1996-01-01
Describes a board game, ImmunoScenarios, which was developed to reinforce the ideas about the immune system discussed in lecture classes. Emphasizes important characteristics of the body's specific defense system including specificity, cooperation among various cells, and memory. Includes directions for playing, student handouts, and scenarios.…
Våge, Selina; Storesund, Julia E.; Giske, Jarl; Thingstad, T. Frede
2014-01-01
Trophic mechanisms that can generate biodiversity in food webs include bottom-up (growth rate regulating) and top-down (biomass regulating) factors. The top-down control has traditionally been analyzed using the concepts of “Keystone Predation” (KP) and “Killing-the-Winner” (KtW), predominately occuring in discussions of macro- and micro-biological ecology, respectively. Here we combine the classical diamond-shaped food web structure frequently discussed in KP analyses and the KtW concept by introducing a defense strategist capable of partial defense. A formalized description of a trade-off between the defense-strategist's competitive and defensive ability is included. The analysis reveals a complex topology of the steady state solution with strong relationships between food web structure and the combination of trade-off, defense strategy and the system's nutrient content. Among the results is a difference in defense strategies corresponding to maximum biomass, production, or net growth rate of invading individuals. The analysis thus summons awareness that biomass or production, parameters typically measured in field studies to infer success of particular biota, are not directly acted upon by natural selection. Under coexistence with a competition specialist, a balance of competitive and defensive ability of the defense strategist was found to be evolutionarily stable, whereas stronger defense was optimal under increased nutrient levels in the absence of the pure competition specialist. The findings of success of different defense strategies are discussed with respect to SAR11, a highly successful bacterial clade in the pelagic ocean. PMID:24999739
Federal Register 2010, 2011, 2012, 2013, 2014
2010-10-25
... DEPARTMENT OF DEFENSE Defense Acquisition Regulations System 48 CFR Parts 219 and 252 [DFARS Case... System AGENCY: Defense Acquisition Regulations System, Department of Defense (DoD). ACTION: Interim rule... Supplement (DFARS) to conform to the Federal Acquisition Regulation (FAR) by providing Department of Defense...
Defense of the United States. Aerospace Education III.
ERIC Educational Resources Information Center
Mickey, V. V.
This publication, one in the series on Aerospace Education III, deals with the background of the defense system of the United States. Description of different wars in which this country was involved includes the development of new military organizations and different weapons. One chapter is devoted in its entirity to the organizational structure…
Instructional Technology in the Department of Defense, Now and in the Future.
ERIC Educational Resources Information Center
Rose, M. Richard
Because the Department of Defense spends more than $7 billion annually on training and educational opportunities, new instructional technologies are constantly explored in an attempt to make education and training more cost effective. Technologies which have been tried include: (1) instructional systems based on behavioral objectives; (2)…
NDAA, RAND Corporation researchers conducted literature reviews, collected and analyzed publicly available and classified data and information , and conducted interviews with subject-matter experts....The National Defense Authorization Act (NDAA) for Fiscal Year 2017, Section 1276, requires an independent assessment directed by the Chairman of the...form of a report, to be delivered to the congressional defense committees. The NDAA requires several specific assessments , including the threat posed to
9th Annual Systems Engineering Conference: Volume-1 Monday Tutorial
2006-10-26
Joint Integrating Concepts (JIC) • Forceable Entry Ops • Undersea Superiority • Global Strike Ops • Sea-Basing Ops • Air & Missile Defense • JC2 • Joint...Forceable Entry Ops o Undersea Superiority o Global Strike Ops o Sea-Basing Ops o Air & Missile Defense o JC2 o Joint Logistics Includes an illustrative... Undersea Superiority • Global Strike Ops • Sea-Basing Ops • Air & Missile Defense • JC2 • Joint Logistics Universal Joint Task List (UJTL) • Strategic
NASA Technical Reports Server (NTRS)
Seasly, Elaine
2015-01-01
To combat contamination of physical assets and provide reliable data to decision makers in the space and missile defense community, a modular open system architecture for creation of contamination models and standards is proposed. Predictive tools for quantifying the effects of contamination can be calibrated from NASA data of long-term orbiting assets. This data can then be extrapolated to missile defense predictive models. By utilizing a modular open system architecture, sensitive data can be de-coupled and protected while benefitting from open source data of calibrated models. This system architecture will include modules that will allow the designer to trade the effects of baseline performance against the lifecycle degradation due to contamination while modeling the lifecycle costs of alternative designs. In this way, each member of the supply chain becomes an informed and active participant in managing contamination risk early in the system lifecycle.
Dong, Ruixia; Wang, Dongxu; Wang, Xiaoxiao; Zhang, Ke; Chen, Pingping; Yang, Chung S; Zhang, Jinsong
2016-12-01
Selenium participates in the antioxidant defense mainly through a class of selenoproteins, including thioredoxin reductase. Epigallocatechin-3-gallate (EGCG) is the most abundant and biologically active catechin in green tea. Depending upon the dose and biological systems, EGCG may function either as an antioxidant or as an inducer of antioxidant defense via its pro-oxidant action or other unidentified mechanisms. By manipulating the selenium status, the present study investigated the interactions of EGCG with antioxidant defense systems including the thioredoxin system comprising of thioredoxin and thioredoxin reductase, the glutathione system comprising of glutathione and glutathione reductase coupled with glutaredoxin, and the Nrf2 system. In selenium-optimal mice, EGCG increased hepatic activities of thioredoxin reductase, glutathione reductase and glutaredoxin. These effects of EGCG appeared to be not due to overt pro-oxidant action because melatonin, a powerful antioxidant, did not influence the increase. However, in selenium-deficient mice, with low basal levels of thioredoxin reductase 1, the same dose of EGCG did not elevate the above-mentioned enzymes; intriguingly EGCG in turn activated hepatic Nrf2 response, leading to increased heme oxygenase 1 and NAD(P)H:quinone oxidoreductase 1 protein levels and thioredoxin activity. Overall, the present work reveals that EGCG is a robust inducer of the Nrf2 system only in selenium-deficient conditions. Under normal physiological conditions, in selenium-optimal mice, thioredoxin and glutathione systems serve as the first line defense systems against the stress induced by high doses of EGCG, sparing the activation of the Nrf2 system. Copyright © 2016 The Authors. Published by Elsevier B.V. All rights reserved.
The Army’s Future Combat System (FCS): Background and Issues for Congress
2008-05-12
Operational Capability 2017 The full attainment of the capability to employ the system, including a fully manned, equipped, trained, and logistically...readiness crisis ,” and that “how FCS funding fits into that equation is yet to be determined.”24 Representative Murtha, Chairman of the House Appropriations...Oversight,” InsideDefense.com, May 7, 2008. 52 Ibid. 53 Ann Roosevelt, “FCS Incurs Schedule Breach, Operational Capability Slips to 2017 ,” Defense Daily
Self-eating and self-defense: autophagy controls innate immunity and adaptive immunity.
Liu, Guangwei; Bi, Yujing; Wang, Ruoning; Wang, Xianghui
2013-04-01
Autophagy (macroautophagy; "self-eating") is a degradation process, in which cytoplasmic content is engulfed and degraded by the lysosome. And, immunity is an important mechanism of the "self-defense" system. Autophagy has long been recognized as a stress response to nutrient deprivation. This will provide energy and anabolic building blocks to maintain cellular bioenergetic homeostasis. Thus, autophagy plays critical roles in regulating a wide variety of pathophysiological processes, including tumorigenesis, embryo development, tissue remodeling, and most recently, immunity. The latter shows that a self-eating (autophagy) process could regulate a self-defense (immune) system. In this review, we summarize the recent findings regarding the regulatory and mechanistic insights of the autophagy pathway in immunity.
National Costs Of The Medical Liability System
Mello, Michelle M.; Chandra, Amitabh; Gawande, Atul A.; Studdert, David M.
2011-01-01
Concerns about reducing the rate of growth of health expenditures have reignited interest in medical liability reforms and their potential to save money by reducing the practice of defensive medicine. It is not easy to estimate the costs of the medical liability system, however. This article identifies the various components of liability system costs, generates national estimates for each component, and discusses the level of evidence available to support the estimates. Overall annual medical liability system costs, including defensive medicine, are estimated to be $55.6 billion in 2008 dollars, or 2.4 percent of total health care spending. PMID:20820010
Automatic speech recognition technology development at ITT Defense Communications Division
NASA Technical Reports Server (NTRS)
White, George M.
1977-01-01
An assessment of the applications of automatic speech recognition to defense communication systems is presented. Future research efforts include investigations into the following areas: (1) dynamic programming; (2) recognition of speech degraded by noise; (3) speaker independent recognition; (4) large vocabulary recognition; (5) word spotting and continuous speech recognition; and (6) isolated word recognition.
Major new thrust for MEMS engines.
Wilson, J R
2003-02-01
The application of microelectromechanical systems (MEMS) to space flight is reviewed. The applications include use as microthrusters on mini-size and smaller satellites, in missile defense systems, and as propulsion systems for miniature unmanned aerial vehicles.
The determinants of defensive medicine in Italian hospitals: The impact of being a second victim.
Panella, M; Rinaldi, C; Leigheb, F; Donnarumma, C; Kul, S; Vanhaecht, K; Di Stanislao, F
2016-07-01
Defensive medicine affects healthcare systems worldwide. The concerns and perception about medical liability could lead practitioners to practise defensive medicine. Second victim is a healthcare worker involved in an unanticipated adverse patient event. The role of being second victim and the other possible determinants for defensive medicine is mostly unclear. To study the condition of being second victim as a possible determinants of defensive medicine among Italian hospital physicians. A secondary analysis of the database of the national survey study on the prevalence and the costs of defensive medicine in Italy that was carried out between April 2014 and June 2014 in 55 Italian hospitals was performed for this study. The demographic section of the questionnaire was selected including the physician's age, gender, specialty, activity volume, grade and the variable being a second victim after an adverse event. A total sample of 1313 physicians (87.5% response rate) was used in the data analyses. Characteristics of the participants included a mean age 49.2 of years and 19.4 average years of experience. The most prominent predictor for practising defensive medicine was the physicians' experience of being a second victim after an adverse event (OR=1.88; 95%CI, 1.38-2.57). Other determinants included age, years of experience, activity volume and risk of specialty. Malpractice reform, effective support to second victims in hospitals together with a systematic use of evidence-based clinical guidelines, emerged as possible recommendations for reducing defensive medicine. Copyright © 2016 SECA. Publicado por Elsevier España, S.L.U. All rights reserved.
Field trial of a diagnostic axis for defense mechanisms for DSM-IV.
Perry, J C; Hoglend, P; Shear, K; Vaillant, G E; Horowitz, M; Kardos, M E; Bille, H; Kagan, D
1998-01-01
Following critiques that the DSM multiaxial system lacks psychodynamic information useful for treatment, an axis for defense mechanisms was developed for DSM-IV, including up to 7 individual defenses from a glossary of 27, and 3 predominant defense levels from a list of 7. We tested the feasibility, reliability, and discriminability of the proposed axis. Clinician and psychiatric resident volunteers were trained at two U.S. and one Norwegian sites. After conducting initial interviews on 107 patients, they rated the DSM-III-R and defense axes, as did a second blind rater. Median kappa reliabilities were .42 (individual defenses), and .47 (defense levels). A summary measure, Overall Defensive Functioning (ODF), had similar reliability to current GAF (IR .68 vs. .62), similar 1-month stability (.75 vs. .78), but greater 6-month stability (.51 vs. .17). Independent of Axis III, ODF had small to moderate associations with other Axes and symptoms. Our findings indicate that the defense axis is a feasible, acceptably reliable, and nonredundant addition to DSM-IV, which may prove useful for planning and conducting treatment.
Strategy alternatives for homeland air and cruise missile defense.
Murphy, Eric M; Payne, Michael D; Vanderwoude, Glenn W
2010-10-01
Air and cruise missile defense of the U.S. homeland is characterized by a requirement to protect a large number of critical assets nonuniformly dispersed over a vast area with relatively few defensive systems. In this article, we explore strategy alternatives to make the best use of existing defense resources and suggest this approach as a means of reducing risk while mitigating the cost of developing and acquiring new systems. We frame the issue as an attacker-defender problem with simultaneous moves. First, we outline and examine the relatively simple problem of defending comparatively few locations with two surveillance systems. Second, we present our analysis and findings for a more realistic scenario that includes a representative list of U.S. critical assets. Third, we investigate sensitivity to defensive strategic choices in the more realistic scenario. As part of this investigation, we describe two complementary computational methods that, under certain circumstances, allow one to reduce large computational problems to a more manageable size. Finally, we demonstrate that strategic choices can be an important supplement to material solutions and can, in some cases, be a more cost-effective alternative. © 2010 Society for Risk Analysis.
The science, technology, and politics of ballistic missile defense
DOE Office of Scientific and Technical Information (OSTI.GOV)
Coyle, Philip E.
America's missile defense systems are deployed at home and abroad. This includes the Groundbased Missile Defense (GMD) system in Alaska and California, the Phased Adaptive Approach in Europe (EPAA), and regional systems in the Middle East and Asia. Unfortunately these systems lack workable architectures, and many of the required elements either don't work or are missing. Major review and reconsideration is needed of all elements of these systems. GMD performance in tests has gotten worse with time, when it ought to be getting better. A lack of political support is not to blame as the DoD spends about $10 billionmore » per year, and proposes to add about $5 billion over the next five years. Russia objects to the EPAA as a threat to its ICBM forces, and to the extensive deployment of U.S. military forces in countries such as Poland, the Czech Republic and Romania, once part of the Soviet Union. Going forward the U.S. should keep working with Russia whose cooperation will be key to diplomatic gains in the Middle East and elsewhere. Meanwhile, America's missile defenses face an enduring set of issues, especially target discrimination in the face of attacks designed to overwhelm the defenses, stage separation debris, chaff, decoys, and stealth. Dealing with target discrimination while also replacing, upgrading, or adding to the many elements of U.S. missiles defenses presents daunting budget priorities. A new look at the threat is warranted, and whether the U.S. needs to consider every nation that possesses even short-range missiles a threat to America. The proliferation of missiles of all sizes around the world is a growing problem, but expecting U.S. missile defenses to deal with all those missiles everywhere is unrealistic, and U.S. missile defenses, effective or not, are justifying more and more offensive missiles.« less
The science, technology, and politics of ballistic missile defense
NASA Astrophysics Data System (ADS)
Coyle, Philip E.
2014-05-01
America's missile defense systems are deployed at home and abroad. This includes the Groundbased Missile Defense (GMD) system in Alaska and California, the Phased Adaptive Approach in Europe (EPAA), and regional systems in the Middle East and Asia. Unfortunately these systems lack workable architectures, and many of the required elements either don't work or are missing. Major review and reconsideration is needed of all elements of these systems. GMD performance in tests has gotten worse with time, when it ought to be getting better. A lack of political support is not to blame as the DoD spends about 10 billion per year, and proposes to add about 5 billion over the next five years. Russia objects to the EPAA as a threat to its ICBM forces, and to the extensive deployment of U.S. military forces in countries such as Poland, the Czech Republic and Romania, once part of the Soviet Union. Going forward the U.S. should keep working with Russia whose cooperation will be key to diplomatic gains in the Middle East and elsewhere. Meanwhile, America's missile defenses face an enduring set of issues, especially target discrimination in the face of attacks designed to overwhelm the defenses, stage separation debris, chaff, decoys, and stealth. Dealing with target discrimination while also replacing, upgrading, or adding to the many elements of U.S. missiles defenses presents daunting budget priorities. A new look at the threat is warranted, and whether the U.S. needs to consider every nation that possesses even short-range missiles a threat to America. The proliferation of missiles of all sizes around the world is a growing problem, but expecting U.S. missile defenses to deal with all those missiles everywhere is unrealistic, and U.S. missile defenses, effective or not, are justifying more and more offensive missiles.
Inducible defenses in food webs: Chapter 3.4
Vos, Matthijs; Kooi, Bob W.; DeAngelis, Donald L.; Mooij, Wolf M.; de Ruiter, Peter; Wolters, Volkmar; Moore, John C.; Melville-Smith, Kimberly
2005-01-01
This chapter reviews the predicted effects of induced defenses on trophic structure and two aspects of stability, “local” stability and persistence, as well as presenting novel results on a third, resilience. Food webs are structures of populations in a given location organized according to their predator–prey interactions. Interaction strengths and, therefore, prey defenses are generally recognized as important ecological factors affecting food webs. Despite this, surprisingly, little light has been shed on the food web-level consequences of inducible defenses. Inducible defenses occur in many taxa in both terrestrial and aquatic food webs. They include refuge use, reduced activity, adaptive life history changes, the production of toxins, synomones and extrafloral nectar, and the formation of colonies, helmets, thorns, or spines. In the chapter, theoretical results for the effects of inducible defenses on trophic structure and the three aspects of stability are reviewed. This is done, in part, using bifurcation analysis—a type of analysis that is applied to nonlinear dynamic systems described by a set of ordinary differential or difference equations. The work presented in the chapter suggests that heterogeneity, as caused by induced defenses in prey species, has major effects on the functioning of food webs. Inducible defenses occur in many species in both aquatic and terrestrial systems, and theoretical work indicates they have major effects on important food web properties such as trophic structure, local stability, persistence, and resilience.
Department of Defense Healthcare Management System Modernization (DHMSM)
2016-03-01
2016 Major Automated Information System Annual Report Department of Defense Healthcare Management System Modernization (DHMSM) Defense...DSN Fax: Date Assigned: November 16, 2015 Program Information Program Name Department of Defense Healthcare Management System Modernization...DHMSM) DoD Component DoD The acquiring DoD Component is Program Executive Office (PEO) Department of Defense (DoD) Healthcare Management Systems (DHMS
Defense Islands in Bacterial and Archaeal Genomes and Prediction of Novel Defense Systems ▿†‡
Makarova, Kira S.; Wolf, Yuri I.; Snir, Sagi; Koonin, Eugene V.
2011-01-01
The arms race between cellular life forms and viruses is a major driving force of evolution. A substantial fraction of bacterial and archaeal genomes is dedicated to antivirus defense. We analyzed the distribution of defense genes and typical mobilome components (such as viral and transposon genes) in bacterial and archaeal genomes and demonstrated statistically significant clustering of antivirus defense systems and mobile genes and elements in genomic islands. The defense islands are enriched in putative operons and contain numerous overrepresented gene families. A detailed sequence analysis of the proteins encoded by genes in these families shows that many of them are diverged variants of known defense system components, whereas others show features, such as characteristic operonic organization, that are suggestive of novel defense systems. Thus, genomic islands provide abundant material for the experimental study of bacterial and archaeal antivirus defense. Except for the CRISPR-Cas systems, different classes of defense systems, in particular toxin-antitoxin and restriction-modification systems, show nonrandom clustering in defense islands. It remains unclear to what extent these associations reflect functional cooperation between different defense systems and to what extent the islands are genomic “sinks” that accumulate diverse nonessential genes, particularly those acquired via horizontal gene transfer. The characteristics of defense islands resemble those of mobilome islands. Defense and mobilome genes are nonrandomly associated in islands, suggesting nonadaptive evolution of the islands via a preferential attachment-like mechanism underpinned by the addictive properties of defense systems such as toxins-antitoxins and an important role of horizontal mobility in the evolution of these islands. PMID:21908672
Defense islands in bacterial and archaeal genomes and prediction of novel defense systems.
Makarova, Kira S; Wolf, Yuri I; Snir, Sagi; Koonin, Eugene V
2011-11-01
The arms race between cellular life forms and viruses is a major driving force of evolution. A substantial fraction of bacterial and archaeal genomes is dedicated to antivirus defense. We analyzed the distribution of defense genes and typical mobilome components (such as viral and transposon genes) in bacterial and archaeal genomes and demonstrated statistically significant clustering of antivirus defense systems and mobile genes and elements in genomic islands. The defense islands are enriched in putative operons and contain numerous overrepresented gene families. A detailed sequence analysis of the proteins encoded by genes in these families shows that many of them are diverged variants of known defense system components, whereas others show features, such as characteristic operonic organization, that are suggestive of novel defense systems. Thus, genomic islands provide abundant material for the experimental study of bacterial and archaeal antivirus defense. Except for the CRISPR-Cas systems, different classes of defense systems, in particular toxin-antitoxin and restriction-modification systems, show nonrandom clustering in defense islands. It remains unclear to what extent these associations reflect functional cooperation between different defense systems and to what extent the islands are genomic "sinks" that accumulate diverse nonessential genes, particularly those acquired via horizontal gene transfer. The characteristics of defense islands resemble those of mobilome islands. Defense and mobilome genes are nonrandomly associated in islands, suggesting nonadaptive evolution of the islands via a preferential attachment-like mechanism underpinned by the addictive properties of defense systems such as toxins-antitoxins and an important role of horizontal mobility in the evolution of these islands.
Military display market: third comprehensive edition
NASA Astrophysics Data System (ADS)
Desjardins, Daniel D.; Hopper, Darrel G.
2002-08-01
Defense displays comprise a niche market whose continually high performance requirements drive technology. The military displays market is being characterized to ascertain opportunities for synergy across platforms, and needs for new technology. All weapons systems are included. Some 382,585 displays are either now in use or planned in DoD weapon systems over the next 15 years, comprising displays designed into direct-view, projection-view, and virtual- image-view applications. This defense niche market is further fractured into 1163 micro-niche markets by the some 403 program offices who make decisions independently of one another. By comparison, a consumer electronics product has volumes of tens-of-millions of units for a single fixed design. Some 81% of defense displays are ruggedized versions of consumer-market driven designs. Some 19% of defense displays, especially in avionics cockpits and combat crewstations, are custom designs to gain the additional performance available in the technology base but not available in consumer-market-driven designs. Defense display sizes range from 13.6 to 4543 mm. More than half of defense displays are now based on some form of flat panel display technology, especially thin-film-transistor active matrix liquid crystal display (TFT AMLCD); the cathode ray tube (CRT) is still widely used but continuing to drop rapidly in defense market share.
Dühring, Sybille; Germerodt, Sebastian; Skerka, Christine; Zipfel, Peter F.; Dandekar, Thomas; Schuster, Stefan
2015-01-01
The diploid, polymorphic yeast Candida albicans is one of the most important human pathogenic fungi. C. albicans can grow, proliferate and coexist as a commensal on or within the human host for a long time. However, alterations in the host environment can render C. albicans virulent. In this review, we describe the immunological cross-talk between C. albicans and the human innate immune system. We give an overview in form of pairs of human defense strategies including immunological mechanisms as well as general stressors such as nutrient limitation, pH, fever etc. and the corresponding fungal response and evasion mechanisms. Furthermore, Computational Systems Biology approaches to model and investigate these complex interactions are highlighted with a special focus on game-theoretical methods and agent-based models. An outlook on interesting questions to be tackled by Systems Biology regarding entangled defense and evasion mechanisms is given. PMID:26175718
Force Health Protection: the mission and political context of the longitudinal health record.
Collmann, Jeff
2009-05-01
Drawing upon an extensive search of publically available literature and discussions at the "National Forum on the Future of the Defense Health Information System," this article documents the evolving mission and political context of the longitudinal health record (LHR) as an instrument for Force Health Protection (FHP). Because of the Gulf War syndrome controversy, the Department of Defense (DoD) launched an ambitious, complex series of programs designed to create a comprehensive, integrated defense health surveillance capability to assure FHP and keep faith with the American people. This "system of systems" includes individual component systems to perform specific functions such as disease surveillance, battlefield assessment, and patient care and consolidates these diverse types of information into centrally accessible archives that serve the interests of occupational health, preventive medicine, medical strategic planning, and longitudinal patient health care. After 25 years of effort and major accomplishments, progress toward a LHR remains uneven and controversy persists.
Staphylococcus aureus Manipulates Innate Immunity through Own and Host-Expressed Proteases.
Pietrocola, Giampiero; Nobile, Giulia; Rindi, Simonetta; Speziale, Pietro
2017-01-01
Neutrophils, complement system and skin collectively represent the main elements of the innate immune system, the first line of defense of the host against many common microorganisms. Bacterial pathogens have evolved strategies to counteract all these defense activities. Specifically, Staphylococcus aureus , a major human pathogen, secretes a variety of immune evasion molecules including proteases, which cleave components of the innate immune system or disrupt the integrity of extracellular matrix and intercellular connections of tissues. Additionally, S. aureus secretes proteins that can activate host zymogens which, in turn, target specific defense components. Secreted proteins can also inhibit the anti-bacterial function of neutrophils or complement system proteases, potentiating S. aureus chances of survival. Here, we review the current understanding of these proteases and modulators of host proteases in the functioning of innate immunity and describe the importance of these mechanisms in the pathology of staphylococcal diseases.
Staphylococcus aureus Manipulates Innate Immunity through Own and Host-Expressed Proteases
Pietrocola, Giampiero; Nobile, Giulia; Rindi, Simonetta; Speziale, Pietro
2017-01-01
Neutrophils, complement system and skin collectively represent the main elements of the innate immune system, the first line of defense of the host against many common microorganisms. Bacterial pathogens have evolved strategies to counteract all these defense activities. Specifically, Staphylococcus aureus, a major human pathogen, secretes a variety of immune evasion molecules including proteases, which cleave components of the innate immune system or disrupt the integrity of extracellular matrix and intercellular connections of tissues. Additionally, S. aureus secretes proteins that can activate host zymogens which, in turn, target specific defense components. Secreted proteins can also inhibit the anti-bacterial function of neutrophils or complement system proteases, potentiating S. aureus chances of survival. Here, we review the current understanding of these proteases and modulators of host proteases in the functioning of innate immunity and describe the importance of these mechanisms in the pathology of staphylococcal diseases. PMID:28529927
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32 CFR 37.620 - What financial management standards do I include for nonprofit participants?
Code of Federal Regulations, 2010 CFR
2010-07-01
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78 FR 41331 - Defense Federal Acquisition Regulation Supplement; Technical Amendments
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Countering MANPADS: study of new concepts and applications
NASA Astrophysics Data System (ADS)
Maltese, Dominique; Robineau, Jacques; Audren, Jean-Thierry; Aragones, Julien; Sailliot, Christophe
2006-05-01
The latest events of ground-to-air Man Portable Air Defense (MANPAD) attacks against aircraft have revealed a new threat both for military and civilian aircraft. Consequently, the implementation of Protecting systems (i.e. Directed InfraRed Counter Measure - DIRCM) in order to face IR guided missiles turns out to be now inevitable. In a near future, aircraft will have to possess detection, tracking, targeting and jamming capabilities to face single and multiple MANPAD threats fired in short-range scenarios from various environments (urban sites, landscape...). In this paper, a practical example of a DIRCM system under study at SAGEM DEFENSE & SECURITY company is presented. The self-protection solution includes built-in and automatic locking-on, tracking, identification and laser jamming capabilities, including defeat assessment. Target Designations are provided by a Missile Warning System. Multiple Target scenarios have been considered to design the system architecture. The article deals with current and future threats (IR seekers of different generations...), scenarios and platforms for system definition. Plus, it stresses on self-protection solutions based on laser jamming capability. Different strategies including target identification, multi band laser, active imagery are described. The self-protection system under study at SAGEM DEFENSE & SECURITY company is also a part of this chapter. Eventually, results of self-protection scenarios are provided for different MANPAD scenarios. Data have been obtained from a simulation software. The results highlight how the system reacts to incoming IR-guided missiles in short time scenarios.
Plant Defense against Insect Herbivores
Fürstenberg-Hägg, Joel; Zagrobelny, Mika; Bak, Søren
2013-01-01
Plants have been interacting with insects for several hundred million years, leading to complex defense approaches against various insect feeding strategies. Some defenses are constitutive while others are induced, although the insecticidal defense compound or protein classes are often similar. Insect herbivory induce several internal signals from the wounded tissues, including calcium ion fluxes, phosphorylation cascades and systemic- and jasmonate signaling. These are perceived in undamaged tissues, which thereafter reinforce their defense by producing different, mostly low molecular weight, defense compounds. These bioactive specialized plant defense compounds may repel or intoxicate insects, while defense proteins often interfere with their digestion. Volatiles are released upon herbivory to repel herbivores, attract predators or for communication between leaves or plants, and to induce defense responses. Plants also apply morphological features like waxes, trichomes and latices to make the feeding more difficult for the insects. Extrafloral nectar, food bodies and nesting or refuge sites are produced to accommodate and feed the predators of the herbivores. Meanwhile, herbivorous insects have adapted to resist plant defenses, and in some cases even sequester the compounds and reuse them in their own defense. Both plant defense and insect adaptation involve metabolic costs, so most plant-insect interactions reach a stand-off, where both host and herbivore survive although their development is suboptimal. PMID:23681010
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The Defense Systems Acquisition and Review Council
1976-09-15
THE DEFENSE SYSTEMS ACQUISITION AND REVIEW COUNCIL.. A Study of Areas of Consideration Affecting the Functions and Process of Defense Major...COUNfIL: 4 Study of Areas of Considerationi Affecting/he Functions and Process of Defense _- 1 Major Systems Acquisition. , ; O,. v AUTHOR(e) I. C...Studies DSARC -- Functions and Process OSDCAIG *, Army Systems . A - =A -- he Defense Systems Acquisition Review Council (DSARC) was created to assume
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Microbial Genomics: The Expanding Universe of Bacterial Defense Systems.
Forsberg, Kevin J; Malik, Harmit S
2018-04-23
Bacteria protect themselves against infection using multiple defensive systems that move by horizontal gene transfer and accumulate in genomic 'defense islands'. A recent study exploited these features to uncover ten novel defense systems, substantially expanding the catalog of bacterial defense systems and predicting the discovery of many more. Copyright © 2018 Elsevier Ltd. All rights reserved.
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2013-11-08
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2013-11-15
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48 CFR 225.7902 - Defense Trade Cooperation Treaties.
Code of Federal Regulations, 2013 CFR
2013-10-01
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48 CFR 225.7902 - Defense Trade Cooperation Treaties.
Code of Federal Regulations, 2014 CFR
2014-10-01
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Commercial-Aircraft Protection System
NASA Astrophysics Data System (ADS)
Case, Russell L., Jr.; Wolff, Peter H.
2004-09-01
Recent world events have identified needs for a commercial aircraft defense system against Man-Portable Air Defense Systems (MANPADS), such as SA-7 and Stinger shoulder launched surface-to-air missiles. Technical challenges include target detection, identification and countermeasures. Political and societal challenges include cost, time to deployment, ground and air safety, and reliability. These challenges, as well as many others, have been met and overcome with the development of Thor Systems' Commercial-Aircraft Protection System (C-APS). C-APS makes use of commercial technology such as radar and infrared sensors with a laser-based countermeasure. Unlike adapted military systems, C-APS detects the threat long before the military versions by employing a 360 degree hemispherical scan, identifying the threat with an infrared sensor and employing a directed laser to not only deflect the target but to permanently disable its seeker. Enhanced capabilities include multiple threat elimination and closed-loop technology for kill verification. All of this is accomplished with development costs less than half that required to convert military technology, manufacturing costs significantly less than competitive products, and a maintenance cycle coincident with standard FAA requirements, which are significantly longer than current systems.
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2010-03-01
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76 FR 48812 - Privacy Act of 1974; System of Records
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32 CFR 637.20 - Security surveillance systems.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 32 National Defense 4 2010-07-01 2010-07-01 true Security surveillance systems. 637.20 Section 637... ENFORCEMENT AND CRIMINAL INVESTIGATIONS MILITARY POLICE INVESTIGATION Investigations § 637.20 Security surveillance systems. Closed circuit video recording systems, to include those with an audio capability, may be...
32 CFR 37.710 - What standards do I include for purchasing systems of nonprofit organizations?
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2010-07-01
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Applications of Should Cost to Achieve Cost Reductions
2014-04-01
Operation of the defense acquisition system . Interim DoD Instruction 5000.02. Washington, DC: Office of the Deputy Secretary of Defense. Gutterman...including suggestions for reducing this burden, to Washington Headquarters Services, Directorate for Information Operations and Reports, 1215 Jefferson...FAR) § 15.407-4 that refers primarily to an extensive review of a contractor’s operations to identify and promote more economical and efficient
32 CFR 21.200 - What is the Defense Grant and Agreement Regulatory System (DGARS)?
Code of Federal Regulations, 2014 CFR
2014-07-01
... 32 National Defense 1 2014-07-01 2014-07-01 false What is the Defense Grant and Agreement Regulatory System (DGARS)? 21.200 Section 21.200 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE DoD GRANT AND AGREEMENT REGULATIONS DoD GRANTS AND AGREEMENTS-GENERAL MATTERS Defense...
32 CFR 21.200 - What is the Defense Grant and Agreement Regulatory System (DGARS)?
Code of Federal Regulations, 2011 CFR
2011-07-01
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32 CFR 21.200 - What is the Defense Grant and Agreement Regulatory System (DGARS)?
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2010-07-01
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32 CFR 21.200 - What is the Defense Grant and Agreement Regulatory System (DGARS)?
Code of Federal Regulations, 2012 CFR
2012-07-01
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32 CFR 21.200 - What is the Defense Grant and Agreement Regulatory System (DGARS)?
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2013-07-01
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75 FR 48278 - Defense Federal Acquisition Regulation Supplement; Excessive Pass-Through Charges
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2010-08-10
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48 CFR 252.215-7002 - Cost estimating system requirements.
Code of Federal Regulations, 2011 CFR
2011-10-01
... Department of Defense to rely upon information produced by the system that is needed for management purposes... management systems; and (4) Is subject to applicable financial control systems. Estimating system means the... estimates of costs and other data included in proposals submitted to customers in the expectation of...
Three applications of backscatter x-ray imaging technology to homeland defense
NASA Astrophysics Data System (ADS)
Chalmers, Alex
2005-05-01
A brief review of backscatter x-ray imaging and a description of three systems currently applying it to homeland defense missions (BodySearch, ZBV and ZBP). These missions include detection of concealed weapons, explosives and contraband on personnel, in vehicles and large cargo containers. An overview of the x-ray imaging subsystems is provided as well as sample images from each system. Key features such as x-ray safety, throughput and detection are discussed. Recent trends in operational modes are described that facilitate 100% inspection at high throughput chokepoints.
Federal Register 2010, 2011, 2012, 2013, 2014
2012-09-24
... DEPARTMENT OF DEFENSE Defense Acquisition Regulations System [OMB Control Number 0704-0321... Financing AGENCY: Defense Acquisition Regulations System, Department of Defense (DoD). ACTION: Notice and... . Paper copies are available from Mr. Mark Gomersall, OUSD(AT&L) DPAP/DARS, Room 3B855, 3060 Defense...
Federal Register 2010, 2011, 2012, 2013, 2014
2011-04-27
... DEPARTMENT OF DEFENSE Defense Acquisition Regulations System 48 CFR Part 207 RIN 0750-AH12 Defense Federal Acquisition Regulation Supplement; Definition of Multiple-Award Contract (DFARS Case 2011-D016) AGENCY: Defense Acquisition Regulations System, Department of Defense (DoD). ACTION: Final rule. SUMMARY...
Federal Register 2010, 2011, 2012, 2013, 2014
2013-06-06
... DEPARTMENT OF DEFENSE Defense Acquisition Regulations System 48 CFR Part 252 RIN Number 0750-AG38 Defense Federal Acquisition Regulation Supplement; Government Support Contractor Access to Technical Data (DFARS 2009-D031); Correction AGENCY: Defense Acquisition Regulations System, Department of Defense (DoD...
Federal Register 2010, 2011, 2012, 2013, 2014
2010-07-13
... DEPARTMENT OF DEFENSE Defense Acquisition Regulations System 48 CFR Parts 205 and 210 Defense Federal Acquisition Regulation Supplement; Publication of Notification of Bundling of Contracts of the Department of Defense (DFARS Case 2009-D033) AGENCY: Defense Acquisition Regulations System, Department of...
Federal Register 2010, 2011, 2012, 2013, 2014
2010-06-15
... DEPARTMENT OF DEFENSE Defense Acquisition Regulations System 48 CFR Parts 202, 203, 212, and 252 [DFARS Case 2009-D015] RIN 0750-AG63 Defense Federal Acquisition Regulation Supplement; Organizational Conflicts of Interest in Major Defense Acquisition Programs AGENCY: Defense Acquisition Regulations System...
Federal Register 2010, 2011, 2012, 2013, 2014
2011-06-06
... DEPARTMENT OF DEFENSE Defense Acquisition Regulations System 48 CFR Part 225 RIN 0750-AH22 Defense Federal Acquisition Regulation Supplement; Fire-Resistant Fiber for Production of Military Uniforms (DFARS Case 2011-D021) AGENCY: Defense Acquisition Regulations System, Department of Defense (DoD). ACTION...
Federal Register 2010, 2011, 2012, 2013, 2014
2013-08-08
... DEPARTMENT OF DEFENSE Defense Acquisition Regulations System 48 CFR Parts 212, 216, 247, and 252...--Transportation (DFARS Case 2012-D057) AGENCY: Defense Acquisition Regulations System, Department of Defense (DoD... manufacture, fabrication, or assembly by the Contractor or any subcontractor. (2) ``Department of Defense...
Federal Register 2010, 2011, 2012, 2013, 2014
2010-12-03
... DEPARTMENT OF DEFENSE Defense Acquisition Regulations System 48 CFR Parts 201, 245, and 252 RIN...-D008) AGENCY: Defense Acquisition Regulations System, Department of Defense (DoD). ACTION: Proposed... demilitarization shall be demilitarized by the Purchaser under the supervision of qualified Department of Defense...
Federal Register 2010, 2011, 2012, 2013, 2014
2012-08-29
... DEPARTMENT OF DEFENSE Defense Acquisition Regulations System 48 CFR Parts 211, 212, and 252 RIN... (DFARS Case 2012-D001) AGENCY: Defense Acquisition Regulations System, Department of Defense (DoD... requirements of the current clause, which requires Defense contractors to report (primarily) Government...
The history of teledermatology in the Department of Defense.
Vidmar, D A
1999-01-01
The Department of Defense (DoD) healthcare system supports the medical needs of service members while engaged in a variety of missions frequently in isolated, remote, and austere locations. As a result, the DoD has been a leader in the development of telemedicine, including teledermatology as a way to provide "good medicine in bad places." A brief technical history of teledermatology, representative DoD experiences including military unique concerns, and a novel approach to increase the access of DoD teledermatology consultation are presented in this article.
Identifying psychotic defenses in a clinical interview.
Berney, Sylvie; de Roten, Yves; Beretta, Véronique; Kramer, Ueli; Despland, Jean-Nicolas
2014-05-01
The Defense Mechanisms Rating Scales (DMRS), one of the most widely used and validated instruments in the study of defense mechanisms, does not include psychotic defenses. The Psychotic-DMRS (P-DMRS) has been developed to include 6 psychotic defense mechanisms: psychotic denial, autistic withdrawal, distortion, delusional projection, fragmentation, and concretization. We discuss psychotic defenses, including the difference between psychotic defenses and psychotic symptoms. Six clinical illustrations demonstrate how the 6 P-DMRS defenses can be identified in patients' narratives selected from the transcripts of dynamic interviews. Implications with respect to patient evaluation and treatment are discussed. © 2014 Wiley Periodicals, Inc.
76 FR 27274 - Defense Federal Acquisition Regulation Supplement; Technical Amendments
Federal Register 2010, 2011, 2012, 2013, 2014
2011-05-11
... DEPARTMENT OF DEFENSE Defense Acquisition Regulations System 48 CFR Part 225 Defense Federal Acquisition Regulation Supplement; Technical Amendments AGENCY: Defense Acquisition Regulations System... Federal Acquisition Regulation Supplement (DFARS) to direct contracting officers to additional guidance on...
Acquisition Planning at the Defense Communications Agency.
1984-04-01
guidelines for interaction are developed under the leadership of DCA agencywide integrators with the participation of personnel from DCA, the Services...Communications System DCSO - Defense Communications System Organizatin . DDN - Defense Data Network DEC - Decision Making DG - Defense Guidance DIA - Defense
76 FR 73602 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2011-11-29
...; System of Records AGENCY: Defense Logistics Agency, Department of Defense (DoD). ACTION: Notice to amend a system of records. SUMMARY: The Defense Logistics Agency is proposing to amend a system of records...: Ms. Jody Sinkler, DLA FOIA/Privacy Act Office, Headquarters, Defense Logistics Agency, ATTN: DGA...
The receptor-like cytoplasmic kinase BSR1 mediates chitin-induced defense signaling in rice cells.
Kanda, Yasukazu; Yokotani, Naoki; Maeda, Satoru; Nishizawa, Yoko; Kamakura, Takashi; Mori, Masaki
2017-08-01
Broad-Spectrum Resistance 1 (BSR1) encodes a rice receptor-like cytoplasmic kinase, and enhances disease resistance when overexpressed. Rice plants overexpressing BSR1 are highly resistant to diverse pathogens, including rice blast fungus. However, the mechanism responsible for this resistance has not been fully characterized. To analyze the BSR1 function, BSR1-knockout (BSR1-KO) plants were generated using a clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-associated protein 9 (Cas9) system. Experiments using suspension-cultured cells revealed that defense responses including H 2 O 2 production (i.e. oxidative burst) and expression of defense-related genes induced by autoclaved conidia of the rice blast fungus significantly decreased in BSR1-KO cells. Furthermore, a treatment with chitin oligomers which function as microbe-associated molecular patterns (MAMPs) of the rice blast fungus resulted in considerably suppressed defense responses in BSR1-KO cells. These results suggest that BSR1 is important for the rice innate immunity triggered by the perception of chitin.
Federal Register 2010, 2011, 2012, 2013, 2014
2012-12-31
... DEPARTMENT OF DEFENSE Defense Acquisition Regulations System 48 CFR Part 202 RIN 0750-AH81 Defense...: Defense Acquisition Regulations System, Department of Defense (DoD). ACTION: Final rule. SUMMARY: DoD is... has either a significant effect beyond the internal operating procedures of the agency issuing the...
Federal Register 2010, 2011, 2012, 2013, 2014
2011-11-18
... DEPARTMENT OF DEFENSE Defense Acquisition Regulations System [Docket No. DARS 2011-0069-0002] Information Collection Requirement; Defense Federal Acquisition Regulation Supplement; Requests for Equitable Adjustment (OMB Control Number 0704-0397) AGENCY: Defense Acquisition Regulations System, Department of...
Unmanned and Unattended Response Capability for Homeland Defense
DOE Office of Scientific and Technical Information (OSTI.GOV)
BENNETT, PHIL C.
2002-11-01
An analysis was conducted of the potential for unmanned and unattended robotic technologies for forward-based, immediate response capabilities that enables access and controlled task performance. The authors analyze high-impact response scenarios in conjunction with homeland security organizations, such as the NNSA Office of Emergency Response, the FBI, the National Guard, and the Army Technical Escort Unit, to cover a range of radiological, chemical and biological threats. They conducted an analysis of the potential of forward-based, unmanned and unattended robotic technologies to accelerate and enhance emergency and crisis response by Homeland Defense organizations. Response systems concepts were developed utilizing new technologiesmore » supported by existing emerging threats base technologies to meet the defined response scenarios. These systems will pre-position robotic and remote sensing capabilities stationed close to multiple sites for immediate action. Analysis of assembled systems included experimental activities to determine potential efficacy in the response scenarios, and iteration on systems concepts and remote sensing and robotic technologies, creating new immediate response capabilities for Homeland Defense.« less
Neuro-immune interactions in inflammation and host defense: Implications for transplantation.
Chavan, Sangeeta S; Ma, Pingchuan; Chiu, Isaac M
2018-03-01
Sensory and autonomic neurons of the peripheral nervous system (PNS) play a critical role in regulating the immune system during tissue inflammation and host defense. Recent studies have identified the molecular mechanisms underlying the bidirectional communication between the nervous system and the immune system. Here, we highlight the studies that demonstrate the importance of the neuro-immune interactions in health and disease. Nociceptor sensory neurons detect immune mediators to produce pain, and release neuropeptides that act on the immune system to regulate inflammation. In parallel, neural reflex circuits including the vagus nerve-based inflammatory reflex are physiological regulators of inflammatory responses and cytokine production. In transplantation, neuro-immune communication could significantly impact the processes of host-pathogen defense, organ rejection, and wound healing. Emerging approaches to target the PNS such as bioelectronics could be useful in improving the outcome of transplantation. Therefore, understanding how the nervous system shapes the immune response could have important therapeutic ramifications for transplantation medicine. © 2017 The American Society of Transplantation and the American Society of Transplant Surgeons.
Network Speech Systems Technology Program
NASA Astrophysics Data System (ADS)
Weinstein, C. J.
1980-09-01
This report documents work performed during FY 1980 on the DCA-sponsored Network Speech Systems Technology Program. The areas of work reported are: (1) communication systems studies in Demand-Assignment Multiple Access (DAMA), voice/data integration, and adaptive routing, in support of the evolving Defense Communications System (DCS) and Defense Switched Network (DSN); (2) a satellite/terrestrial integration design study including the functional design of voice and data interfaces to interconnect terrestrial and satellite network subsystems; and (3) voice-conferencing efforts dealing with support of the Secure Voice and Graphics Conferencing (SVGC) Test and Evaluation Program. Progress in definition and planning of experiments for the Experimental Integrated Switched Network (EISN) is detailed separately in an FY 80 Experiment Plan Supplement.
78 FR 69076 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2013-11-18
... DEPARTMENT OF DEFENSE Office of the Secretary [Docket ID: DoD-2013-OS-0216] Privacy Act of 1974; System of Records AGENCY: Defense Health Agency, DoD. ACTION: Notice to amend nineteen Record Systems..., Department of Defense. Defense Health Agency How Systems of Records Are Designated In the Department of...
76 FR 46756 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2011-08-03
...; System of Records AGENCY: Missile Defense Agency, Department of Defense (DoD). ACTION: Notice to Delete a System of Records. SUMMARY: The Missile Defense Agency proposes to delete a system of records notice in.... Peter Shearston, Missile Defense Agency, MDA/DXCM, 730 Irwin Ave, Schriever AFB, CO 80912-2101, or by...
78 FR 43866 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2013-07-22
... INFORMATION CONTACT or at the Defense Privacy and Civil Liberties Web site at http://dpclo.defense.gov/privacy... DEPARTMENT OF DEFENSE Office of the Secretary [Docket ID: DoD-2013-OS-0136] Privacy Act of 1974; System of Records AGENCY: Defense Information Systems Agency, DoD. ACTION: Notice to delete a System of...
Increasing the Mobility of Dismounted Marines
2009-10-01
actually been the inspiration for military UGV development programs, including the Defense Advanced Research Projects Agency’s (DARPA) Legged Squad Support...or wheel-based; only the BigDog is a leg -based system. This presented BigDog with certain advantages (particularly involving its ability to traverse...1,000 pounds) Website: http://www.dtiweb.net/index.html 50 General Discussion: Ranlo The Ranlo – named after Defense Technologies, Inc.’s ( DTI
Behind Human Error: Cognitive Systems, Computers and Hindsight
1994-12-01
evaluations • Organize and/or conduct workshops and conferences CSERIAC is a Department of Defense Information Analysis Cen- ter sponsored by the Defense...Process 185 Neutral Observer Criteria 191 Error Analysis as Causal Judgment 193 Error as Information 195 A Fundamental Surprise 195 What is Human...Kahnemann, 1974), and in risk analysis (Dougherty and Fragola, 1990). The discussions have continued in a wide variety of forums, includ- ing the
78 FR 25972 - Establishment of the Response Systems to Adult Sexual Crimes Panel
Federal Register 2010, 2011, 2012, 2013, 2014
2013-05-03
.... 920 (Article 120 of the UCMJ). The Response Systems Panel's review shall include the following: a... recommendations and advice to the Response Systems Panel for full deliberation and discussion. Subcommittees, task... DEPARTMENT OF DEFENSE Office of the Secretary Establishment of the Response Systems to Adult...
48 CFR 217.7404-2 - Price ceiling.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Price ceiling. 217.7404-2 Section 217.7404-2 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM... Contract Actions 217.7404-2 Price ceiling. UCAs shall include a not-to-exceed price. ...
Code of Federal Regulations, 2014 CFR
2014-10-01
... 48 Federal Acquisition Regulations System 3 2014-10-01 2014-10-01 false Scope. 225.7402-1 Section 225.7402-1 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT... subsection may include stability operations such as— (1) Establishment or maintenance of a safe and secure...
Code of Federal Regulations, 2012 CFR
2012-10-01
... 48 Federal Acquisition Regulations System 3 2012-10-01 2012-10-01 false Scope. 225.7402-1 Section 225.7402-1 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT... subsection may include stability operations such as— (1) Establishment or maintenance of a safe and secure...
Code of Federal Regulations, 2010 CFR
2010-10-01
... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Scope. 225.7402-1 Section 225.7402-1 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT... subsection may include stability operations such as— (1) Establishment or maintenance of a safe and secure...
Code of Federal Regulations, 2011 CFR
2011-10-01
... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Scope. 225.7402-1 Section 225.7402-1 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT... subsection may include stability operations such as— (1) Establishment or maintenance of a safe and secure...
Code of Federal Regulations, 2013 CFR
2013-10-01
... 48 Federal Acquisition Regulations System 3 2013-10-01 2013-10-01 false Scope. 225.7402-1 Section 225.7402-1 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT... subsection may include stability operations such as— (1) Establishment or maintenance of a safe and secure...
Rode-Margono, Johanna E; Nekaris, K Anne-Isola
2015-07-17
Venom delivery systems (VDS) are common in the animal kingdom, but rare amongst mammals. New definitions of venom allow us to reconsider its diversity amongst mammals by reviewing the VDS of Chiroptera, Eulipotyphla, Monotremata, and Primates. All orders use modified anterior dentition as the venom delivery apparatus, except Monotremata, which possesses a crural system. The venom gland in most taxa is a modified submaxillary salivary gland. In Primates, the saliva is activated when combined with brachial gland exudate. In Monotremata, the crural spur contains the venom duct. Venom functions include feeding, intraspecific competition, anti-predator defense and parasite defense. Including mammals in discussion of venom evolution could prove vital in our understanding protein functioning in mammals and provide a new avenue for biomedical and therapeutic applications and drug discovery.
Rode-Margono, Johanna E.; Nekaris, K. Anne-Isola
2015-01-01
Venom delivery systems (VDS) are common in the animal kingdom, but rare amongst mammals. New definitions of venom allow us to reconsider its diversity amongst mammals by reviewing the VDS of Chiroptera, Eulipotyphla, Monotremata, and Primates. All orders use modified anterior dentition as the venom delivery apparatus, except Monotremata, which possesses a crural system. The venom gland in most taxa is a modified submaxillary salivary gland. In Primates, the saliva is activated when combined with brachial gland exudate. In Monotremata, the crural spur contains the venom duct. Venom functions include feeding, intraspecific competition, anti-predator defense and parasite defense. Including mammals in discussion of venom evolution could prove vital in our understanding protein functioning in mammals and provide a new avenue for biomedical and therapeutic applications and drug discovery. PMID:26193318
Federal Register 2010, 2011, 2012, 2013, 2014
2012-02-24
... DEPARTMENT OF DEFENSE Defense Acquisition Regulations System 48 CFR Part 219 and Appendix I to Chapter 2 RIN 0750-AH59 Defense Federal Acquisition Regulation Supplement; Extension of the Department of... Regulations System, Department of Defense (DoD). ACTION: Final rule. SUMMARY: DoD is issuing this final rule...
32 CFR 37.1025 - Must I report information to the Defense Assistance Awards Data System?
Code of Federal Regulations, 2010 CFR
2010-07-01
... 32 National Defense 1 2010-07-01 2010-07-01 false Must I report information to the Defense Assistance Awards Data System? 37.1025 Section 37.1025 National Defense Department of Defense OFFICE OF THE... Award Reporting Information About the Award § 37.1025 Must I report information to the Defense...
32 CFR 37.1025 - Must I report information to the Defense Assistance Awards Data System?
Code of Federal Regulations, 2014 CFR
2014-07-01
... 32 National Defense 1 2014-07-01 2014-07-01 false Must I report information to the Defense Assistance Awards Data System? 37.1025 Section 37.1025 National Defense Department of Defense OFFICE OF THE... Award Reporting Information About the Award § 37.1025 Must I report information to the Defense...
32 CFR 37.1025 - Must I report information to the Defense Assistance Awards Data System?
Code of Federal Regulations, 2012 CFR
2012-07-01
... 32 National Defense 1 2012-07-01 2012-07-01 false Must I report information to the Defense Assistance Awards Data System? 37.1025 Section 37.1025 National Defense Department of Defense OFFICE OF THE... Award Reporting Information About the Award § 37.1025 Must I report information to the Defense...
32 CFR 37.1025 - Must I report information to the Defense Assistance Awards Data System?
Code of Federal Regulations, 2013 CFR
2013-07-01
... 32 National Defense 1 2013-07-01 2013-07-01 false Must I report information to the Defense Assistance Awards Data System? 37.1025 Section 37.1025 National Defense Department of Defense OFFICE OF THE... Award Reporting Information About the Award § 37.1025 Must I report information to the Defense...
32 CFR 37.1025 - Must I report information to the Defense Assistance Awards Data System?
Code of Federal Regulations, 2011 CFR
2011-07-01
... 32 National Defense 1 2011-07-01 2011-07-01 false Must I report information to the Defense Assistance Awards Data System? 37.1025 Section 37.1025 National Defense Department of Defense OFFICE OF THE... Award Reporting Information About the Award § 37.1025 Must I report information to the Defense...
2016-04-30
Defense: Doing Data Right in Weapon System Acquisition Nancy Moore, Senior Management Scientist, RAND Megan McKernan, Defense Research Analyst...Access to Acquisition Data & Information in the Department of Defense: Doing Data Right in Weapon System Acquisition Nancy Moore, Senior Management...With Access to Acquisition Data and Information in the Department of Defense: Doing Data Right in Weapon System Acquisition Nancy Y. Moore—is a
Yan, Sandra C; Hulou, M Maher; Cote, David J; Roytowski, David; Rutka, James T; Gormley, William B; Smith, Timothy R
2016-11-01
Perception of medicolegal risk has been shown to influence defensive medicine behaviors. Canada, South Africa, and the United States have 3 vastly different health care and medicolegal systems. There has been no previous study comparing defensive medicine practices internationally. An online survey was sent to 3672 neurosurgeons across Canada, South Africa, and the United States. The survey included questions on the following domains: surgeon demographics, patient characteristics, physician practice type, surgeon liability profile, defensive behavior-including questions on the frequency of ordering additional imaging, laboratory tests, and consults-and perception of the liability environment. Responses were analyzed, and multivariate logistic regression was used to examine the correlation of medicolegal risk environment and defensive behavior. The response rate was 30.3% in the United States (n = 1014), 36.5% in Canada (n = 62), and 41.8% in South Africa (n = 66). Canadian neurosurgeons reported an average annual malpractice premium of $19,110 (standard deviation [SD] = $11,516), compared with $16,262 (SD = $7078) for South African respondents, $75,857 (SD = $50,775) for neurosurgeons from low-risk U.S. states, and $128,181 (SD = $79,355) for those from high-risk U.S. states. Neurosurgeons from South Africa were 2.8 times more likely to engage in defensive behaviors compared with Canadian neurosurgeons, while neurosurgeons from low-risk U.S. states were 2.6 times more likely. Neurosurgeons from high-risk U.S. states were 4.5 times more likely to practice defensively compared with Canadian neurosurgeons. Neurosurgeons from the United States and South Africa are more likely to practice defensively than neurosurgeons from Canada. Perception of medicolegal risk is correlated with reported neurosurgical defensive medicine within these countries. Copyright © 2016 Elsevier Inc. All rights reserved.
Study on combat effectiveness of air defense missile weapon system based on queuing theory
NASA Astrophysics Data System (ADS)
Zhao, Z. Q.; Hao, J. X.; Li, L. J.
2017-01-01
Queuing Theory is a method to analyze the combat effectiveness of air defense missile weapon system. The model of service probability based on the queuing theory was constructed, and applied to analyzing the combat effectiveness of "Sidewinder" and "Tor-M1" air defense missile weapon system. Finally aimed at different targets densities, the combat effectiveness of different combat units of two types' defense missile weapon system is calculated. This method can be used to analyze the usefulness of air defense missile weapon system.
Federal Register 2010, 2011, 2012, 2013, 2014
2012-01-19
... DEPARTMENT OF DEFENSE Defense Acquisition Regulations System 48 CFR Parts 212 and 252 RIN 0750-AH27 Defense Federal Acquisition Regulation Supplement; Pilot Program for Acquisition of Military-Purpose Nondevelopmental Items (DFARS Case 2011-D034) AGENCY: Defense Acquisition Regulations System...
Nakad, Rania; Snoek, L Basten; Yang, Wentao; Ellendt, Sunna; Schneider, Franziska; Mohr, Timm G; Rösingh, Lone; Masche, Anna C; Rosenstiel, Philip C; Dierking, Katja; Kammenga, Jan E; Schulenburg, Hinrich
2016-04-11
The invertebrate immune system comprises physiological mechanisms, physical barriers and also behavioral responses. It is generally related to the vertebrate innate immune system and widely believed to provide nonspecific defense against pathogens, whereby the response to different pathogen types is usually mediated by distinct signalling cascades. Recent work suggests that invertebrate immune defense can be more specific at least at the phenotypic level. The underlying genetic mechanisms are as yet poorly understood. We demonstrate in the model invertebrate Caenorhabditis elegans that a single gene, a homolog of the mammalian neuropeptide Y receptor gene, npr-1, mediates contrasting defense phenotypes towards two distinct pathogens, the Gram-positive Bacillus thuringiensis and the Gram-negative Pseudomonas aeruginosa. Our findings are based on combining quantitative trait loci (QTLs) analysis with functional genetic analysis and RNAseq-based transcriptomics. The QTL analysis focused on behavioral immune defense against B. thuringiensis, using recombinant inbred lines (RILs) and introgression lines (ILs). It revealed several defense QTLs, including one on chromosome X comprising the npr-1 gene. The wildtype N2 allele for the latter QTL was associated with reduced defense against B. thuringiensis and thus produced an opposite phenotype to that previously reported for the N2 npr-1 allele against P. aeruginosa. Analysis of npr-1 mutants confirmed these contrasting immune phenotypes for both avoidance behavior and nematode survival. Subsequent transcriptional profiling of C. elegans wildtype and npr-1 mutant suggested that npr-1 mediates defense against both pathogens through p38 MAPK signaling, insulin-like signaling, and C-type lectins. Importantly, increased defense towards P. aeruginosa seems to be additionally influenced through the induction of oxidative stress genes and activation of GATA transcription factors, while the repression of oxidative stress genes combined with activation of Ebox transcription factors appears to enhance susceptibility to B. thuringiensis. Our findings highlight the role of a single gene, npr-1, in fine-tuning nematode immune defense, showing the ability of the invertebrate immune system to produce highly specialized and potentially opposing immune responses via single regulatory genes.
Herzog, Quirin; Laforsch, Christian
2013-11-18
Inducible defenses are a common and widespread form of phenotypic plasticity. A fundamental factor driving their evolution is an unpredictable and heterogeneous predation pressure. This heterogeneity is often used synonymously to quantitative changes in predation risk, depending on the abundance and impact of predators. However, differences in 'modality', that is, the qualitative aspect of natural selection caused by predators, can also cause heterogeneity. For instance, predators of the small planktonic crustacean Daphnia have been divided into two functional groups of predators: vertebrates and invertebrates. Predators of both groups are known to cause different defenses, yet predators of the same group are considered to cause similar responses. In our study we question that thought and address the issue of how multiple predators affect the expression and evolution of inducible defenses. We exposed D. barbata to chemical cues released by Triops cancriformis and Notonecta glauca, respectively. We found for the first time that two invertebrate predators induce different shapes of the same morphological defensive traits in Daphnia, rather than showing gradual or opposing reaction norms. Additionally, we investigated the adaptive value of those defenses in direct predation trials, pairing each morphotype (non-induced, Triops-induced, Notonecta-induced) against the other two and exposed them to one of the two predators. Interestingly, against Triops, both induced morphotypes offered equal protection. To explain this paradox we introduce a 'concept of modality' in multipredator regimes. Our concept categorizes two-predator-prey systems into three major groups (functionally equivalent, functionally inverse and functionally diverse). Furthermore, the concept includes optimal responses and costs of maladaptions of prey phenotypes in environments where both predators co-occur or where they alternate. With D. barbata, we introduce a new multipredator-prey system with a wide array of morphological inducible defenses. Based on a 'concept of modality', we give possible explanations how evolution can favor specialized defenses over a general defense. Additionally, our concept not only helps to classify different multipredator-systems, but also stresses the significance of costs of phenotype-environment mismatching in addition to classic 'costs of plasticity'. With that, we suggest that 'modality' matters as an important factor in understanding and explaining the evolution of inducible defenses.
Defenses and morality: Adam Smith, Sigmund Freud, and contemporary psychoanalysis.
Gabrinetti, Paul A; Özler, Sule
2014-10-01
In this paper we follow the development and transmission of moral learning from Adam Smith's impartial spectator to Sigmund Freud's superego and then to contemporary psychoanalysis. We argue that defenses are an integral component in the acquisition of any moral system. Elaborating on this argument, we assert that there is a progression from defensive systems that are "closed" to defensive systems that are "open," as defined in a recent work by Novick and Novick. The former system is "static, avoids reality, and is characterized by power dynamics, sadomasochism, and omnipotent defense." The latter, on the other hand, is a system that allows for "joy, creativity, spontaneity, love and it is attuned to reality." Furthermore, while Smith and Freud's systems are more one-person systems of defense, contemporary psychoanalysis has moved to more of a two-person system.
Missile Defense: Ballistic Missile Defense System Testing Delays Affect Delivery of Capabilities
2016-04-28
Page 1 GAO- 16 -339R Ballistic Missile Defense 441 G St. N.W. Washington, DC 20548 April 28, 2016 Congressional Committees Missile Defense...Ballistic Missile Defense System Testing Delays Affect Delivery of Capabilities For over half a century , the Department of Defense (DOD) has been...81, § 232 (a) (2011). 2 GAO- 16 -339R Ballistic Missile Defense baselines, we analyzed the testing goals for selected elements, which are
75 FR 13091 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2010-03-18
... automated, near real-time readiness reporting system that provides resource standards and current readiness... the Department of Defense to establish a capabilities-based, adaptive, near real-time readiness... capability to assess plans using real unit data. Routine uses of records maintained in the system, including...
76 FR 63287 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2011-10-12
... DEPARTMENT OF DEFENSE Office of the Secretary [Docket ID DOD-2011-OS-0110] Privacy Act of 1974; System of Records AGENCY: Office of the Secretary of Defense, Department of Defense (DoD). ACTION: Notice..., Alternate OSD Federal Register Liaison Officer, Department of Defense. DHA 22 System name: Medical...
32 CFR 322.7 - Exempt systems of records.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 32 National Defense 2 2013-07-01 2013-07-01 false Exempt systems of records. 322.7 Section 322.7 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) PRIVACY PROGRAM NATIONAL SECURITY AGENCY/CENTRAL SECURITY SERVICES PRIVACY ACT PROGRAM § 322.7 Exempt systems of...
32 CFR 322.7 - Exempt systems of records.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 32 National Defense 2 2012-07-01 2012-07-01 false Exempt systems of records. 322.7 Section 322.7 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) PRIVACY PROGRAM NATIONAL SECURITY AGENCY/CENTRAL SECURITY SERVICES PRIVACY ACT PROGRAM § 322.7 Exempt systems of...
32 CFR 322.7 - Exempt systems of records.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 32 National Defense 2 2014-07-01 2014-07-01 false Exempt systems of records. 322.7 Section 322.7 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) PRIVACY PROGRAM NATIONAL SECURITY AGENCY/CENTRAL SECURITY SERVICES PRIVACY ACT PROGRAM § 322.7 Exempt systems of...
32 CFR 322.7 - Exempt systems of records.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 32 National Defense 2 2011-07-01 2011-07-01 false Exempt systems of records. 322.7 Section 322.7 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) PRIVACY PROGRAM NATIONAL SECURITY AGENCY/CENTRAL SECURITY SERVICES PRIVACY ACT PROGRAM § 322.7 Exempt systems of...
Federal Register 2010, 2011, 2012, 2013, 2014
2013-06-06
... DEPARTMENT OF DEFENSE Defense Acquisition Regulations System 48 CFR Part 204 RIN 0750-AH80 Defense Federal Acquisition Regulation Supplement; Clarification of ``F'' Orders in the Procurement Instrument Identification Number Structure (DFARS Case 2012-D040); Correction AGENCY: Defense Acquisition Regulations System...
Federal Register 2010, 2011, 2012, 2013, 2014
2012-06-15
... DEPARTMENT OF DEFENSE Defense Acquisition Regulations System 48 CFR Parts 211, 212, 218, 246, 252 and Appendix F to Chapter 2 RIN 0750-AH64 Defense Federal Acquisition Regulation Supplement: Item Unique Identifier Update (DFARS Case 2011-D055) AGENCY: Defense Acquisition Regulations System...
Federal Register 2010, 2011, 2012, 2013, 2014
2011-02-02
... DEPARTMENT OF DEFENSE Defense Acquisition Regulations System 48 CFR Parts 245 and 252 [DFARS Case 2008-D049] RIN 0750-AG64 Defense Federal Acquisition Regulation Supplement; Reporting of Government Property Lost, Stolen, Damaged, or Destroyed AGENCY: Defense Acquisition Regulations System; Department of...
Federal Register 2010, 2011, 2012, 2013, 2014
2011-04-19
... DEPARTMENT OF DEFENSE Defense Acquisition Regulations System 48 CFR Part 213 RIN 0750-AH07 Defense Federal Acquisition Regulation Supplement; Ships Bunkers Easy Acquisition (SEA) Card[supreg] and Aircraft Ground Services (DFARS Case 2009-D019) AGENCY: Defense Acquisition Regulations System, Department of...
Federal Register 2010, 2011, 2012, 2013, 2014
2011-09-20
... DEPARTMENT OF DEFENSE Defense Acquisition Regulations System 48 CFR Part 213 RIN 0750-AH07 Defense Federal Acquisition Regulation Supplement; Ships Bunkers Easy Acquisition (SEA) Card[supreg] and Aircraft Ground Services (DFARS Case 2009-D019) AGENCY: Defense Acquisition Regulations System, Department of...
Federal Register 2010, 2011, 2012, 2013, 2014
2010-04-22
... DEPARTMENT OF DEFENSE Defense Acquisition Regulations System 48 CFR Parts 202, 203, 212, and 252 RIN 0750-AG63 Defense Federal Acquisition Regulation Supplement; Organizational Conflicts of Interest... System, Department of Defense (DoD). ACTION: Proposed rule with request for comments. SUMMARY: DoD is...
The natural defense system and the normative self model
Kourilsky, Philippe
2016-01-01
Infectious agents are not the only agressors, and the immune system is not the sole defender of the organism. In an enlarged perspective, the ‘normative self model’ postulates that a ‘natural defense system’ protects man and other complex organisms against the environmental and internal hazards of life, including infections and cancers. It involves multiple error detection and correction mechanisms that confer robustness to the body at all levels of its organization. According to the model, the self relies on a set of physiological norms, and NONself (meaning : Non Obedient to the Norms of the self) is anything ‘off-norms’. The natural defense system comprises a set of ‘civil defenses’ (to which all cells in organs and tissues contribute), and a ‘professional army ‘, made of a smaller set of mobile cells. Mobile and non mobile cells differ in their tuning abilities. Tuning extends the recognition capabilities of NONself by the mobile cells, which increase their defensive function. To prevent them to drift, which would compromise self/NONself discrimination, the more plastic mobile cells need to periodically refer to the more stable non mobile cells to keep within physiological standards. PMID:27303629
49 CFR 1.84 - The Federal Highway Administration.
Code of Federal Regulations, 2013 CFR
2013-10-01
... environment. (e) Surveying and constructing forest highway system roads, defense highways and access roads... surveillance of accident locations; highway design, construction, and maintenance, including context sensitive...
48 CFR 239.7100 - Scope of subpart.
Code of Federal Regulations, 2010 CFR
2010-10-01
... OF DEFENSE SPECIAL CATEGORIES OF CONTRACTING ACQUISITION OF INFORMATION TECHNOLOGY Security and Privacy for Computer Systems 239.7100 Scope of subpart. This subpart includes information assurance and...
48 CFR 239.7100 - Scope of subpart.
Code of Federal Regulations, 2014 CFR
2014-10-01
... OF DEFENSE SPECIAL CATEGORIES OF CONTRACTING ACQUISITION OF INFORMATION TECHNOLOGY Security and Privacy for Computer Systems 239.7100 Scope of subpart. This subpart includes information assurance and...
48 CFR 239.7100 - Scope of subpart.
Code of Federal Regulations, 2011 CFR
2011-10-01
... OF DEFENSE SPECIAL CATEGORIES OF CONTRACTING ACQUISITION OF INFORMATION TECHNOLOGY Security and Privacy for Computer Systems 239.7100 Scope of subpart. This subpart includes information assurance and...
48 CFR 239.7100 - Scope of subpart.
Code of Federal Regulations, 2012 CFR
2012-10-01
... OF DEFENSE SPECIAL CATEGORIES OF CONTRACTING ACQUISITION OF INFORMATION TECHNOLOGY Security and Privacy for Computer Systems 239.7100 Scope of subpart. This subpart includes information assurance and...
48 CFR 239.7100 - Scope of subpart.
Code of Federal Regulations, 2013 CFR
2013-10-01
... OF DEFENSE SPECIAL CATEGORIES OF CONTRACTING ACQUISITION OF INFORMATION TECHNOLOGY Security and Privacy for Computer Systems 239.7100 Scope of subpart. This subpart includes information assurance and...
Code of Federal Regulations, 2011 CFR
2011-01-01
... Administrative Personnel DEPARTMENT OF DEFENSE HUMAN RESOURCES MANAGEMENT AND LABOR RELATIONS SYSTEMS (DEPARTMENT OF DEFENSE-OFFICE OF PERSONNEL MANAGEMENT) DEPARTMENT OF DEFENSE NATIONAL SECURITY PERSONNEL SYSTEM...-for-performance evaluation system means the performance management system established under this...
Code of Federal Regulations, 2014 CFR
2014-07-01
... Notice in Federal Register Format E Appendix E to Part 310 National Defense Department of Defense... Format (See paragraph (f) of § 310.30) New system of records notice DEPARTMENT OF DEFENSE Office of the..., Department of Defense. NSLRB 01 System name: The National Security Labor Relations Board (NSLRB). System...
NASA Astrophysics Data System (ADS)
Qi, Bin; Guo, Linli; Zhang, Zhixian
2016-07-01
Space life science and life support engineering are prominent problems in manned deep space exploration mission. Some typical problems are discussed in this paper, including long-term life support problem, physiological effect and defense of varying extraterrestrial environment. The causes of these problems are developed for these problems. To solve these problems, research on space life science and space medical-engineering should be conducted. In the aspect of space life science, the study of space gravity biology should focus on character of physiological effect in long term zero gravity, co-regulation of physiological systems, impact on stem cells in space, etc. The study of space radiation biology should focus on target effect and non-target effect of radiation, carcinogenicity of radiation, spread of radiation damage in life system, etc. The study of basic biology of space life support system should focus on theoretical basis and simulating mode of constructing the life support system, filtration and combination of species, regulation and optimization method of life support system, etc. In the aspect of space medical-engineering, the study of bio-regenerative life support technology should focus on plants cultivation technology, animal-protein production technology, waste treatment technology, etc. The study of varying gravity defense technology should focus on biological and medical measures to defend varying gravity effect, generation and evaluation of artificial gravity, etc. The study of extraterrestrial environment defense technology should focus on risk evaluation of radiation, monitoring and defending of radiation, compound prevention and removal technology of dust, etc. At last, a case of manned lunar base is analyzed, in which the effective schemes of life support system, defense of varying gravity, defense of extraterrestrial environment are advanced respectively. The points in this paper can be used as references for intensive study on key technologies.
76 FR 79660 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2011-12-22
...; System of Records AGENCY: Defense Information Systems Agency, DoD. ACTION: Notice to delete a system of records. SUMMARY: The Defense Information Systems Agency is deleting one system of records notices in its...: Ms. Jeanette M. Weathers-Jenkins, Defense Information Systems Agency, 6916 Cooper Avenue, Fort Meade...
75 FR 25219 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2010-05-07
... SYSTEM: Badge and vehicle control records that at a minimum include: Name, Social Security Number (SSN... SYSTEM: 10 U.S.C. 8013, Secretary of the Air Force, Powers and Duties; Department of Defense 5200.08-R... SYSTEM: STORAGE: Electronic storage media. RETRIEVABILITY: Data is retrieved by querying a driver's name...
78 FR 73511 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2013-12-06
... DEPARTMENT OF DEFENSE [Docket ID: USN-2013-0046] Privacy Act of 1974; System of Records AGENCY... Privacy Act of 1974, as amended. The system being deleted is N01500-8, System Name: Personnel and Training... Internet at http://www.regulations.gov as they are received without change, including any personal...
78 FR 52517 - Membership of the Performance Review Board
Federal Register 2010, 2011, 2012, 2013, 2014
2013-08-23
... Agency, Defense Contract Audit Agency, Defense Contract Management Agency, Defense Finance and Accounting Service, Defense Information Systems Agency, Defense Legal Services Agency, Defense Logistics Agency...
77 FR 49440 - Membership of the Performance Review Board
Federal Register 2010, 2011, 2012, 2013, 2014
2012-08-16
... Agency, Defense Contract Audit Agency, Defense Contract Management Agency, Defense Finance And Accounting Service, Defense Information Systems Agency, Defense Legal Services Agency, Defense Logistics Agency...
77 FR 40861 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2012-07-11
... DEPARTMENT OF DEFENSE Office of the Secretary [Docket ID: DOD-2012-OS-0084] Privacy Act of 1974... Officer, Department of Defense. DHRA 10 DoD System name: Defense Sexual Assault Advocate Certification.... SUMMARY: The Office of the Secretary of Defense proposes to add a new system of records in its inventory...
76 FR 72689 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2011-11-25
... DEPARTMENT OF DEFENSE Office of the Secretary [Docket ID: DOD-2011-OS-0131] Privacy Act of 1974; System of Records AGENCY: Office of the Secretary of Defense, Department of Defense (DoD). ACTION: Notice..., Alternate OSD Federal Register Liaison Officer, Department of Defense. DWHS E01 DoD System name: DoD Federal...
48 CFR 2452.239-70 - Access to HUD systems.
Code of Federal Regulations, 2014 CFR
2014-10-01
.... 2452.239-70 Section 2452.239-70 Federal Acquisition Regulations System DEPARTMENT OF HOUSING AND URBAN... secret in the interest of national defense or foreign policy. System means an interconnected set of... investigation (NACI or other OPM-required or approved investigation), including an FBI National Criminal History...
75 FR 60431 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2010-09-30
..., Department of Defense. DPR 41 DoD System Name: Combined Mild Traumatic Brain Injury Registry. System Location... concussive or mild traumatic brain injury and/or related incidents in deployed settings, to include blast... Type Memoranda 09-033, Policy Guidance for Management of Concussion/Mild Traumatic Brain Injury in the...
2009-12-01
Business Process Modeling BPMN Business Process Modeling Notation SoA Service-oriented Architecture UML Unified Modeling Language CSP...system developers. Supporting technologies include Business Process Modeling Notation ( BPMN ), Unified Modeling Language (UML), model-driven architecture
32 CFR 327.5 - Systems of records.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 32 National Defense 2 2014-07-01 2014-07-01 false Systems of records. 327.5 Section 327.5 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) PRIVACY PROGRAM... disclosure within the Department of Defense (DoD). The contractor is considered the agent of DeCA and is to...
32 CFR Appendix E to Part 247 - DoD Command Newspaper and Magazine Review System
Code of Federal Regulations, 2013 CFR
2013-07-01
... 32 National Defense 2 2013-07-01 2013-07-01 false DoD Command Newspaper and Magazine Review System E Appendix E to Part 247 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) MISCELLANEOUS DEPARTMENT OF DEFENSE NEWSPAPERS, MAGAZINES AND CIVILIAN...
32 CFR Appendix E to Part 247 - DoD Command Newspaper and Magazine Review System
Code of Federal Regulations, 2011 CFR
2011-07-01
... 32 National Defense 2 2011-07-01 2011-07-01 false DoD Command Newspaper and Magazine Review System E Appendix E to Part 247 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) MISCELLANEOUS DEPARTMENT OF DEFENSE NEWSPAPERS, MAGAZINES AND CIVILIAN...
32 CFR Appendix E to Part 247 - DoD Command Newspaper and Magazine Review System
Code of Federal Regulations, 2014 CFR
2014-07-01
... 32 National Defense 2 2014-07-01 2014-07-01 false DoD Command Newspaper and Magazine Review System E Appendix E to Part 247 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) MISCELLANEOUS DEPARTMENT OF DEFENSE NEWSPAPERS, MAGAZINES AND CIVILIAN...
32 CFR Appendix E to Part 247 - DoD Command Newspaper and Magazine Review System
Code of Federal Regulations, 2012 CFR
2012-07-01
... 32 National Defense 2 2012-07-01 2012-07-01 false DoD Command Newspaper and Magazine Review System E Appendix E to Part 247 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) MISCELLANEOUS DEPARTMENT OF DEFENSE NEWSPAPERS, MAGAZINES AND CIVILIAN...
2015-05-01
Director, Operational Test and Evaluation Department of Defense (DOD) Automated Biometric Identification System (ABIS) Version 1.2 Initial...Operational Test and Evaluation Report May 2015 This report on the Department of Defense (DOD) Automated Biometric Identification System...COVERED - 4. TITLE AND SUBTITLE Department of Defense (DOD) Automated Biometric Identification System (ABIS) Version 1.2 Initial Operational Test
An Analysis of Turkey’s Defense Systems Acquisition Policy
2009-03-01
i NAVAL POSTGRADUATE SCHOOL MONTEREY, CALIFORNIA MBA PROFESSIONAL REPORT An Analysis of Turkey’s Defense Systems Acquisition...2009 3. REPORT TYPE AND DATES COVERED MBA THESIS 4. TITLE AND SUBTITLE An Analysis of Turkey’s Defense Systems Acquisition Policy 6. AUTHOR(S...DISTRIBUTION CODE 13. ABSTRACT (maximum 200 words) The purpose of this MBA thesis is to analyze Turkey’s defense systems acquisition policy and
2012-09-01
III. THE DEFENSE MARKETPLACE A. DEFENSE INDUSTRY OVERVIEW The market of the defense industry in the United States is different than the commercial...marketplace in a number of respects. Lorell, Lowell, Kennedy, and Levaux (2000) defined the uniqueness of the U.S. defense market in two ways. First...the U.S. defense market for weapon systems is characterized by a single buyer (Lorell et al., 2000, p. 13). “The second distinguishing feature of
32 CFR 37.405 - What must my announcement or solicitation include?
Code of Federal Regulations, 2010 CFR
2010-07-01
... 32 National Defense 1 2010-07-01 2010-07-01 false What must my announcement or solicitation include? 37.405 Section 37.405 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE... competitive procedure, must include the basic information described in 32 CFR 22.315(a). Additional elements...
Code of Federal Regulations, 2010 CFR
2010-01-01
... Administrative Personnel DEPARTMENT OF DEFENSE HUMAN RESOURCES MANAGEMENT AND LABOR RELATIONS SYSTEMS (DEPARTMENT OF DEFENSE-OFFICE OF PERSONNEL MANAGEMENT) DEPARTMENT OF DEFENSE NATIONAL SECURITY PERSONNEL SYSTEM... of Defense and the Director of the Office of Personnel Management (OPM). The Secretary may establish...
Code of Federal Regulations, 2011 CFR
2011-01-01
... Administrative Personnel DEPARTMENT OF DEFENSE HUMAN RESOURCES MANAGEMENT AND LABOR RELATIONS SYSTEMS (DEPARTMENT OF DEFENSE-OFFICE OF PERSONNEL MANAGEMENT) DEPARTMENT OF DEFENSE NATIONAL SECURITY PERSONNEL SYSTEM... of Defense and the Director of the Office of Personnel Management (OPM). The Secretary may establish...
77 FR 58816 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2012-09-24
... DEPARTMENT OF DEFENSE Office of the Secretary [Docket ID: DoD-2012-OS-0094] Privacy Act of 1974; System of Records AGENCY: Defense Information Systems Agency, DoD. ACTION: Notice to delete five Systems of Records. SUMMARY: The Defense Information Systems Agency is deleting five systems of records...
Code of Federal Regulations, 2010 CFR
2000-10-01
... 48 Federal Acquisition Regulations System 3 2000-10-01 2000-10-01 false Content. 206.303-2 Section 206.303-2 Federal Acquisition Regulations System DEPARTMENT OF DEFENSE ACQUISITION PLANNING COMPETITION REQUIREMENTS Other Than Full and Open Competition 206.303-2 Content. (a) Include sufficient...
48 CFR 208.7400 - Scope of subpart.
Code of Federal Regulations, 2010 CFR
2010-10-01
... OF DEFENSE ACQUISITION PLANNING REQUIRED SOURCES OF SUPPLIES AND SERVICES Enterprise Software... commercial software and software maintenance, including software and software maintenance that is acquired— (a) As part of a system or system upgrade, where practicable; (b) Under a service contract; (c) Under...
Neural networks: Application to medical imaging
NASA Technical Reports Server (NTRS)
Clarke, Laurence P.
1994-01-01
The research mission is the development of computer assisted diagnostic (CAD) methods for improved diagnosis of medical images including digital x-ray sensors and tomographic imaging modalities. The CAD algorithms include advanced methods for adaptive nonlinear filters for image noise suppression, hybrid wavelet methods for feature segmentation and enhancement, and high convergence neural networks for feature detection and VLSI implementation of neural networks for real time analysis. Other missions include (1) implementation of CAD methods on hospital based picture archiving computer systems (PACS) and information networks for central and remote diagnosis and (2) collaboration with defense and medical industry, NASA, and federal laboratories in the area of dual use technology conversion from defense or aerospace to medicine.
The AFJROTC Program at Hopewell High School
ERIC Educational Resources Information Center
Schultes, Charles R., Jr.
1975-01-01
Describes the textbooks, the curricular, and co-curricular activities in the AFJROTC program at Hopewell High School. Includes a description of a specialized, fourth-year course extension which includes celestial navigation, communicative techniques, computer systems, meteorology, and Air Force Role in National Defense. (MLH)
Depth Perception and Defensive System Activation in a 3-D Environment
Combe, Emmanuelle; Fujii, Naotaka
2011-01-01
To survive, animals must be able to react appropriately (in temporal and behavioral terms) when facing a threat. One of the essential parameters considered by the defensive system is the distance of the threat, the “defensive distance.” In this study, we investigate the visual depth cues that could be considered as an alarm cue for the activation of the defensive system. For this purpose, we performed an active-escape pain task in a virtual three-dimensional environment. In two experiments, we manipulated the nature and consistency of different depth cues: vergence, linear perspective, and angular size. By measuring skin conductance responses, we characterized the situations that activated the defensive system. We show that the angular size of the predator was sufficient information to trigger responses from the defensive system, but we also demonstrate that vergence, which can delay the emotional response in inconsistent situations, is also a highly reliable cue for the activation of the defensive system. PMID:21941515
War-gaming application for future space systems acquisition
NASA Astrophysics Data System (ADS)
Nguyen, Tien M.; Guillen, Andy T.
2016-05-01
Recently the U.S. Department of Defense (DOD) released the Defense Innovation Initiative (DII) [1] to focus DOD on five key aspects; Aspect #1: Recruit talented and innovative people, Aspect #2: Reinvigorate war-gaming, Aspect #3: Initiate long-range research and development programs, Aspect #4: Make DOD practices more innovative, and Aspect #5: Advance technology and new operational concepts. Per DII instruction, this paper concentrates on Aspect #2 and Aspect #4 by reinvigorating the war-gaming effort with a focus on an innovative approach for developing the optimum Program and Technical Baselines (PTBs) and their corresponding optimum acquisition strategies for acquiring future space systems. The paper describes a unified approach for applying the war-gaming concept for future DOD acquisition of space systems. The proposed approach includes a Unified Game-based Acquisition Framework (UGAF) and an Advanced Game-Based Mathematical Framework (AGMF) using Bayesian war-gaming engines to optimize PTB solutions and select the corresponding optimum acquisition strategies for acquiring a space system. The framework defines the action space for all players with a complete description of the elements associated with the games, including Department of Defense Acquisition Authority (DAA), stakeholders, warfighters, and potential contractors, War-Gaming Engines (WGEs) played by DAA, WGEs played by Contractor (KTR), and the players' Payoff and Cost functions (PCFs). The AGMF presented here addresses both complete and incomplete information cases. The proposed framework provides a recipe for the DAA and USAF-Space and Missile Systems Center (SMC) to acquire future space systems optimally.
Musidlak, Oskar; Nawrot, Robert; Goździcka-Józefiak, Anna
2017-11-01
Plants have evolved a variety of defense mechanisms to tackle virus attack. Endogenous plant proteins can function as virus suppressors. Different types of proteins mediate defense responses against plant viruses. Pathogenesis-related (PR) proteins are activated upon pathogen infections or in different stress situations and their production is one of many components in plant defense. Ribosome-inactivating proteins (RIPs) suppress translation by enzymatically damaging ribosomes and they have been found to have antiviral activity. RNA-binding proteins (RBPs) bind to target RNAs via specialized RNA-binding domain and can directly or indirectly function in plant defense system against RNA viruses. Proteins involved in silencing machinery, namely Dicer-like (DCL) proteins, Argonaute (AGO) proteins, and RNA-dependent RNA polymerases (RDRs) confer innate antiviral defense in plants as they are able to degrade foreign RNA of viral origin. This review aims to provide a comprehensive and up-to-date picture of plant proteins participating in antiviral defense. As a result we discuss proteins conferring plant antiviral resistance and their potential future applications in different fields of life including agriculture and medicine.
Goździcka-Józefiak, Anna
2017-01-01
Plants have evolved a variety of defense mechanisms to tackle virus attack. Endogenous plant proteins can function as virus suppressors. Different types of proteins mediate defense responses against plant viruses. Pathogenesis-related (PR) proteins are activated upon pathogen infections or in different stress situations and their production is one of many components in plant defense. Ribosome-inactivating proteins (RIPs) suppress translation by enzymatically damaging ribosomes and they have been found to have antiviral activity. RNA-binding proteins (RBPs) bind to target RNAs via specialized RNA-binding domain and can directly or indirectly function in plant defense system against RNA viruses. Proteins involved in silencing machinery, namely Dicer-like (DCL) proteins, Argonaute (AGO) proteins, and RNA-dependent RNA polymerases (RDRs) confer innate antiviral defense in plants as they are able to degrade foreign RNA of viral origin. This review aims to provide a comprehensive and up-to-date picture of plant proteins participating in antiviral defense. As a result we discuss proteins conferring plant antiviral resistance and their potential future applications in different fields of life including agriculture and medicine. PMID:29104238
Protecting Networks Via Automated Defense of Cyber Systems
2016-09-01
autonomics, and artificial intelligence . Our conclusion is that automation is the future of cyber defense, and that advances are being made in each of...SUBJECT TERMS Internet of Things, autonomics, sensors, artificial intelligence , cyber defense, active cyber defense, automated indicator sharing...called Automated Defense of Cyber Systems, built upon three core technological components: sensors, autonomics, and artificial intelligence . Our
32 CFR Appendix C to Part 323 - Instructions for Preparation of Reports to New or Altered Systems
Code of Federal Regulations, 2012 CFR
2012-07-01
... 32 National Defense 2 2012-07-01 2012-07-01 false Instructions for Preparation of Reports to New or Altered Systems C Appendix C to Part 323 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) PRIVACY PROGRAM DEFENSE LOGISTICS AGENCY PRIVACY PROGRAM Pt...
32 CFR Appendix C to Part 323 - Instructions for Preparation of Reports to New or Altered Systems
Code of Federal Regulations, 2011 CFR
2011-07-01
... 32 National Defense 2 2011-07-01 2011-07-01 false Instructions for Preparation of Reports to New or Altered Systems C Appendix C to Part 323 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) PRIVACY PROGRAM DEFENSE LOGISTICS AGENCY PRIVACY PROGRAM Pt...
Farjad, Elham; Momeni, Hamid Reza
2018-10-01
Cadmium is an environmental pollutant which induces oxidative stress while silymarin as an antioxidant is able to scavenge free radicals. The aim of the present study was to investigate the effect of silymarin on oxidative stress markers and antioxidant defense system capacity in mice treated with cadmium chloride. In this experimental study, adult mice were divided into four groups as follow: i. Control, ii. Cadmium chloride (5 mg/kg b.w., s.c.), iii. Silymarin+cadmium chloride, and iv. Silymarin (100 mg/kg b.w., i.p.). Mice were treated with cadmium chloride for 24 hours and silymarin was administered 24 hours before the cadmium. Blood samples were then collected from the experimental groups and their sera were prepared. To investigate oxidative stress markers in the serum, the amount of malondialdehyde (MDA) and thiol groups (-SH) were evaluated. To measure the total antioxidant power in the serum, Ferric Reducing/ Antioxidant Power (FRAP) method was used. In addition, the activity of enzymes including catalase (CAT), superoxide dismutase (SOD) and glutathione peroxidase (GPx) was assessed to evaluate serum antioxidant defense power. In the cadmium-treated group, the amount of MDA significantly increased as compared to the control group. In silymarin+cadmium group, silymarin significantly ameliorated the level of MDA compared to the cadmium group. In addition, cadmium significantly reduced serum FRAP, the activity of antioxidant defense system enzymes and thiol groups compared to the control. In silymarin+cadmium group, silymarin could significantly reverse the reduction of these markers compared to the cadmium group. Administration of silymarin alone caused a significant increase in serum FRAP, the activity of antioxidant defense system enzymes and thiol groups compared to the control group. Silymarin as a powerful antioxidant reverses the toxic effect of cadmium on the serum levels of lipid peroxidation, total antioxidant power, antioxidant defense system enzymes activity and thiol groups. Copyright© by Royan Institute. All rights reserved.
48 CFR 228.102-70 - Defense Environmental Restoration Program construction contracts.
Code of Federal Regulations, 2010 CFR
2010-10-01
... Restoration Program construction contracts. 228.102-70 Section 228.102-70 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE GENERAL CONTRACTING REQUIREMENTS BONDS AND INSURANCE Bonds 228.102-70 Defense Environmental Restoration Program construction contracts...
Duke, Kelly A; Becker, Michael G; Girard, Ian J; Millar, Jenna L; Dilantha Fernando, W G; Belmonte, Mark F; de Kievit, Teresa R
2017-06-19
The biological control agent Pseudomonas chlororaphis PA23 is capable of protecting Brassica napus (canola) from the necrotrophic fungus Sclerotinia sclerotiorum via direct antagonism. While we have elucidated bacterial genes and gene products responsible biocontrol, little is known about how the host plant responds to bacterial priming on the leaf surface, including global changes in gene activity in the presence and absence of S. sclerotiorum. Application of PA23 to the aerial surfaces of canola plants reduced the number of S. sclerotiorum lesion-forming petals by 91.1%. RNA sequencing of the host pathogen interface showed that pretreatment with PA23 reduced the number of genes upregulated in response to S. sclerotiorum by 16-fold. By itself, PA23 activated unique defense networks indicative of defense priming. Genes encoding MAMP-triggered immunity receptors detecting flagellin and peptidoglycan were downregulated in PA23 only-treated plants, consistent with post-stimulus desensitization. Downstream, we observed reactive oxygen species (ROS) production involving low levels of H 2 O 2 and overexpression of genes associated with glycerol-3-phosphate (G3P)-mediated systemic acquired resistance (SAR). Leaf chloroplasts exhibited increased thylakoid membrane structures and chlorophyll content, while lipid metabolic processes were upregulated. In addition to directly antagonizing S. sclerotiorum, PA23 primes the plant defense response through induction of unique local and systemic defense networks. This study provides novel insight into the effects of biocontrol agents applied to the plant phyllosphere. Understanding these interactions will aid in the development of biocontrol systems as an alternative to chemical pesticides for protection of important crop systems.
75 FR 81247 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2010-12-27
... Control Records system of records is also covered by the Defense Finance and Accounting System T7330a... Defense Finance and Accounting System T7332, Defense Debt Management System (February 17, 2009, 74 FR 7665... of 1974; System of Records AGENCY: Office of the Secretary, DoD. ACTION: Notice to delete three...
32 CFR Appendix F to Part 286 - DoD Freedom of Information Act Program Components
Code of Federal Regulations, 2010 CFR
2010-07-01
... Defense Information Systems Agency Defense Contract Audit Agency Defense Intelligence Agency Defense Security Service Defense Logistics Agency National Imagery and Mapping Agency Defense Special Weapons Agency National Security Agency Office of the Inspector General, Department of Defense Defense Finance...
78 FR 27194 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2013-05-09
...; System of Records AGENCY: Defense Finance and Accounting Service, DoD. ACTION: Notice to delete a System of Records. SUMMARY: The Defense Finance and Accounting Service is deleting a system of records...: The Defense Finance and Accounting Service systems of records notices subject to the Privacy Act of...
77 FR 60400 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2012-10-03
...; System of Records AGENCY: Defense Finance and Accounting Service. ACTION: Notice to delete two systems of records. SUMMARY: The Defense Finance and Accounting Service is deleting two systems of records notices in.... SUPPLEMENTARY INFORMATION: The Defense Finance and Accounting Service systems of records notices subject to the...
78 FR 69392 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2013-11-19
...; System of Records AGENCY: Defense Finance and Accounting Service, DoD. ACTION: Notice to delete a system of records. SUMMARY: The Defense Finance and Accounting Service is deleting a system of records... INFORMATION: The Defense Finance and Accounting Service systems of records notices subject to the Privacy Act...
78 FR 6078 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2013-01-29
...; System of Records AGENCY: Defense Finance and Accounting Service, DoD. ACTION: Notice to delete a system of records. SUMMARY: The Defense Finance and Accounting Service is deleting a system of records.... SUPPLEMENTARY INFORMATION: The Defense Finance and Accounting Service systems of records notices subject to the...
78 FR 27194 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2013-05-09
...; System of Records AGENCY: Defense Finance and Accounting Service, DoD. ACTION: Notice to delete two Systems of Records. SUMMARY: The Defense Finance and Accounting Service is deleting two systems of records...: The Defense Finance and Accounting Service systems of records notices subject to the Privacy Act of...
77 FR 65370 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2012-10-26
...; System of Records AGENCY: Defense Finance and Accounting Service, DoD. ACTION: Notice to delete a Systems of Records. SUMMARY: The Defense Finance and Accounting Service is deleting a system of records.... SUPPLEMENTARY INFORMATION: The Defense Finance and Accounting Service systems of records notices subject to the...
75 FR 17910 - Privacy Act of 1974; Systems of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2010-04-08
...; Systems of Records AGENCY: Defense Logistics Agency, DoD. ACTION: Notice to delete a system of records. SUMMARY: The Defense Logistics Agency proposes to delete a system of records notice in its existing...-5045. SUPPLEMENTARY INFORMATION: The Defense Logistics Agency systems of records notices subject to the...
75 FR 15694 - Privacy Act of 1974; Systems of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2010-03-30
...; Systems of Records AGENCY: Defense Logistics Agency, DoD. ACTION: Notice to delete a system of records. SUMMARY: The Defense Logistics Agency proposes to delete a system of records notice in its existing...-5045. SUPPLEMENTARY INFORMATION: The Defense Logistics Agency systems of records notices subject to the...
75 FR 33792 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2010-06-15
... instructions for submitting comments. Mail: Federal Docket Management System Office, 1160 Defense Pentagon...; System of Records AGENCY: Defense Intelligence Agency, DoD. ACTION: Notice to add a system of records. SUMMARY: The Defense Intelligence proposes to add a system of records notice to its inventory of record...
75 FR 52515 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2010-08-26
...; System of Records AGENCY: Defense Logistics Agency, DoD. ACTION: Notice to alter a system of records. SUMMARY: The Defense Logistics Agency proposes to alter a system of records notice in its existing.... Jody Sinkler at (703) 767-5045. SUPPLEMENTARY INFORMATION: The Defense Logistics Agency systems of...
75 FR 19377 - Privacy Act of 1974; Systems of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2010-04-14
...; Systems of Records AGENCY: Defense Logistics Agency, DoD. ACTION: Notice to alter a system of records. SUMMARY: The Defense Logistics Agency proposes to alter a system of records notice in its existing...-5045. SUPPLEMENTARY INFORMATION: The Defense Logistics Agency systems of records notices subject to the...
75 FR 20580 - Privacy Act of 1974; Systems of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2010-04-20
...; Systems of Records AGENCY: Defense Logistics Agency, DoD. ACTION: Notice to amend a system of records. SUMMARY: The Defense Logistics Agency proposes to amend a system of records notice in its existing.... SUPPLEMENTARY INFORMATION: The Defense Logistics Agency systems of records notices subject to the Privacy Act of...
75 FR 10473 - Privacy Act of 1974; Systems of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2010-03-08
...; Systems of Records AGENCY: Defense Logistics Agency, DoD. ACTION: Notice to amend a system of records. SUMMARY: The Defense Logistics Agency proposes to amend a system of records notice in its existing...-5045. SUPPLEMENTARY INFORMATION: The Defense Logistics Agency systems of records notices subject to the...
76 FR 53420 - Privacy Act of 1974; Systems of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2011-08-26
...; Systems of Records AGENCY: Defense Logistics Agency, Department of Defense (DoD). ACTION: Notice to Delete a System of Records. SUMMARY: The Defense Logistics Agency proposes to delete a system of records... Docket Management System Office, 4800 Mark Center Drive, Suite 02G09, Alexandria, VA 22350-3100...
75 FR 17904 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2010-04-08
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75 FR 26201 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2010-05-11
...; System of Records AGENCY: Defense Intelligence Agency, DoD. ACTION: Notice to amend a system of records. SUMMARY: The Defense Intelligence Agency is proposing to amend a system in its existing inventory of.... SUPPLEMENTARY INFORMATION: The Defense Intelligence Agency systems of records notices subject to the Privacy Act...
75 FR 30791 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2010-06-02
...; System of Records AGENCY: Defense Intelligence Agency, DoD. ACTION: Notice to alter a system of records. SUMMARY: The Defense Intelligence Agency is proposing to alter a system of records in its existing... Lowery at (202) 231-1193. SUPPLEMENTARY INFORMATION: The Defense Intelligence Agency system of records...
77 FR 77047 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2012-12-31
...; System of Records AGENCY: Defense Contract Audit Agency, DoD. ACTION: Notice to delete a Systems of Records. SUMMARY: The Defense Contract Audit Agency (DCAA) is deleting a system of records in its existing... at (703) 767-1022. SUPPLEMENTARY INFORMATION: The Defense Contract Audit Agency (DCAA) systems of...
77 FR 77048 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2012-12-31
...; System of Records AGENCY: Defense Contract Audit Agency, DoD. ACTION: Notice to amend a System of Records. SUMMARY: The Defense Contract Audit Agency is amending a system of records notice in its existing.... SUPPLEMENTARY INFORMATION: The Defense Contract Audit Agency systems of records notices subject to the Privacy...
78 FR 27195 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2013-05-09
...; System of Records AGENCY: Defense Finance and Accounting Service, DoD. ACTION: Notice to delete two Systems of Records. SUMMARY: The Defense Finance and Accounting Service is deleting two systems of records...: The Defense Finance and Accounting Service systems of records notices subject to the Privacy Act of...
78 FR 31905 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2013-05-28
...; System of Records AGENCY: Defense Finance and Accounting Service, DoD. ACTION: Notice to amend a System of Records. SUMMARY: The Defense Finance and Accounting Service is amending a system of records...: The Defense Finance and Accounting Service systems of records notices subject to the Privacy Act of...
75 FR 21248 - Privacy Act of 1974; Systems of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2010-04-23
...; Systems of Records AGENCY: Defense Finance and Accounting Service, DoD. ACTION: Notice to alter a system of records. SUMMARY: The Defense Finance and Accounting Service (DFAS) is proposing to alter a system...) 522-5225. SUPPLEMENTARY INFORMATION: The Defense Finance and Accounting Service notices for systems of...
Protected by fumigants: beetle perfumes in antimicrobial defense.
Gross, Jürgen; Schumacher, Kerstin; Schmidtberg, Henrike; Vilcinskas, Andreas
2008-02-01
Beetles share with other eukaryotes an innate immune system that mediates endogenous defense against pathogens. In addition, larvae of some taxa produce fluid exocrine secretions that contain antimicrobial compounds. In this paper, we provide evidence that larvae of the brassy willow leaf beetle Phratora vitellinae constitutively release volatile glandular secretions that combat pathogens in their microenvironment. We identified salicylaldehyde as the major component of their enveloping perfume cloud, which is emitted by furrow-shaped openings of larval glandular reservoirs and which inhibits in vitro the growth of the bacterial entomopathogen Bacillus thuringiensis. The suggested role of salicylaldehyde as a fumigant in exogenous antimicrobial defense was confirmed in vivo by its removal from glandular reservoirs. This resulted in an enhanced susceptibility of the larvae to infection with the fungal entomopathogens Beauveria bassiana and Metarhizium anisopliae. Consequently, we established the hypothesis that antimicrobial defense in beetles can be expanded beyond innate immunity to include external disinfection of their microenvironment, and we report for the first time the contribution of fumigants to antimicrobial defense in animals.
77 FR 56625 - Privacy Act of 1974; Systems of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2012-09-13
... Internet at http://www.regulations.gov as they are received without change, including any personal.... George G. Meade, MD 20755-6000. Decentralized segments: Defense Intelligence Agency (DIA) Headquarters... decentralized system locations, write to the National Security Agency/Central Security Service, Freedom of...
Self/nonself perception in plants in innate immunity and defense
Sanabria, Natasha M; Huang, Ju-Chi
2010-01-01
The ability to distinguish ‘self’ from ‘nonself’ is the most fundamental aspect of any immune system. The evolutionary solution in plants to the problems of perceiving and responding to pathogens involves surveillance of nonself, damaged-self and altered-self as danger signals. This is reflected in basal resistance or non-host resistance, which is the innate immune response that protects plants against the majority of pathogens. In the case of surveillance of nonself, plants utilize receptor-like proteins or -kinases (RLP/Ks) as pattern recognition receptors (PRRs), which can detect conserved pathogen/microbe-associated molecular pattern (P/MAMP) molecules. P/MAMP detection serves as an early warning system for the presence of a wide range of potential pathogens and the timely activation of plant defense mechanisms. However, adapted microbes express a suite of effector proteins that often interfere or act as suppressors of these defenses. In response, plants have evolved a second line of defense that includes intracellular nucleotide binding leucine-rich repeat (NB-LRR)-containing resistance proteins, which recognize isolate-specific pathogen effectors once the cell wall has been compromised. This host-immunity acts within the species level and is controlled by polymorphic host genes, where resistance protein-mediated activation of defense is based on an ‘altered-self’ recognition mechanism. PMID:21559176
75 FR 47797 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2010-08-09
... DEPARTMENT OF DEFENSE Defense Logistics Agency [Docket ID: DOD-2010-OS-0110] Privacy Act of 1974; System of Records AGENCY: Defense Logistics Agency, DoD. ACTION: Notice to delete a system of records. [[Page 47798
48 CFR 252.244-7001 - Contractor purchasing system administration.
Code of Federal Regulations, 2012 CFR
2012-10-01
... system administration. 252.244-7001 Section 252.244-7001 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CLAUSES AND FORMS SOLICITATION PROVISIONS AND CONTRACT... that materially affects the ability of officials of the Department of Defense to rely upon information...
48 CFR 252.244-7001 - Contractor purchasing system administration.
Code of Federal Regulations, 2011 CFR
2011-10-01
... system administration. 252.244-7001 Section 252.244-7001 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CLAUSES AND FORMS SOLICITATION PROVISIONS AND CONTRACT... that materially affects the ability of officials of the Department of Defense to rely upon information...
48 CFR 252.244-7001 - Contractor purchasing system administration.
Code of Federal Regulations, 2013 CFR
2013-10-01
... system administration. 252.244-7001 Section 252.244-7001 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CLAUSES AND FORMS SOLICITATION PROVISIONS AND CONTRACT... that materially affects the ability of officials of the Department of Defense to rely upon information...
Human-machine analytics for closed-loop sense-making in time-dominant cyber defense problems
NASA Astrophysics Data System (ADS)
Henry, Matthew H.
2017-05-01
Many defense problems are time-dominant: attacks progress at speeds that outpace human-centric systems designed for monitoring and response. Despite this shortcoming, these well-honed and ostensibly reliable systems pervade most domains, including cyberspace. The argument that often prevails when considering the automation of defense is that while technological systems are suitable for simple, well-defined tasks, only humans possess sufficiently nuanced understanding of problems to act appropriately under complicated circumstances. While this perspective is founded in verifiable truths, it does not account for a middle ground in which human-managed technological capabilities extend well into the territory of complex reasoning, thereby automating more nuanced sense-making and dramatically increasing the speed at which it can be applied. Snort1 and platforms like it enable humans to build, refine, and deploy sense-making tools for network defense. Shortcomings of these platforms include a reliance on rule-based logic, which confounds analyst knowledge of how bad actors behave with the means by which bad behaviors can be detected, and a lack of feedback-informed automation of sensor deployment. We propose an approach in which human-specified computational models hypothesize bad behaviors independent of indicators and then allocate sensors to estimate and forecast the state of an intrusion. State estimates and forecasts inform the proactive deployment of additional sensors and detection logic, thereby closing the sense-making loop. All the while, humans are on the loop, rather than in it, permitting nuanced management of fast-acting automated measurement, detection, and inference engines. This paper motivates and conceptualizes analytics to facilitate this human-machine partnership.
22 CFR 120.9 - Defense service.
Code of Federal Regulations, 2010 CFR
2010-04-01
... Defense service. (a) Defense service means: (1) The furnishing of assistance (including training) to..., destruction, processing or use of defense articles; (2) The furnishing to foreign persons of any technical...) Military training of foreign units and forces, regular and irregular, including formal or informal...
48 CFR 245.7203 - Assigning plant clearance case numbers.
Code of Federal Regulations, 2010 CFR
2010-10-01
... Q—Navy E—Air Force L—Marine Corps U—Defense Logistics Agency N—Defense Nuclear Agency M—National... case numbers. 245.7203 Section 245.7203 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CONTRACT MANAGEMENT GOVERNMENT PROPERTY Special Instructions 245...
48 CFR 214.407-3 - Other mistakes disclosed before award.
Code of Federal Regulations, 2010 CFR
2010-10-01
...) Missile Defense Agency: General Counsel, MDA. (ix) Defense Contract Management Agency: General Counsel... before award. 214.407-3 Section 214.407-3 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CONTRACTING METHODS AND CONTRACT TYPES SEALED BIDDING Opening of...
48 CFR 214.407-3 - Other mistakes disclosed before award.
Code of Federal Regulations, 2013 CFR
2013-10-01
...) Missile Defense Agency: General Counsel, MDA. (ix) Defense Contract Management Agency: General Counsel... before award. 214.407-3 Section 214.407-3 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CONTRACTING METHODS AND CONTRACT TYPES SEALED BIDDING Opening of...
48 CFR 214.407-3 - Other mistakes disclosed before award.
Code of Federal Regulations, 2012 CFR
2012-10-01
...) Missile Defense Agency: General Counsel, MDA. (ix) Defense Contract Management Agency: General Counsel... before award. 214.407-3 Section 214.407-3 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CONTRACTING METHODS AND CONTRACT TYPES SEALED BIDDING Opening of...
48 CFR 214.407-3 - Other mistakes disclosed before award.
Code of Federal Regulations, 2011 CFR
2011-10-01
...) Missile Defense Agency: General Counsel, MDA. (ix) Defense Contract Management Agency: General Counsel... before award. 214.407-3 Section 214.407-3 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CONTRACTING METHODS AND CONTRACT TYPES SEALED BIDDING Opening of...
48 CFR 214.407-3 - Other mistakes disclosed before award.
Code of Federal Regulations, 2014 CFR
2014-10-01
...) Missile Defense Agency: General Counsel, MDA. (ix) Defense Contract Management Agency: General Counsel... before award. 214.407-3 Section 214.407-3 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CONTRACTING METHODS AND CONTRACT TYPES SEALED BIDDING Opening of...
32 CFR 1290.2 - Purpose and scope.
Code of Federal Regulations, 2010 CFR
2010-07-01
... National Defense Other Regulations Relating to National Defense DEFENSE LOGISTICS AGENCY MISCELLANEOUS... Federal Magistrate System by DLA. This part 1290 is applicable to HQ DLA, Defense Supply Centers (DSC's), less Defense Fuel Supply Center and Defense Industrial Supply Center, and to Defense Depots, less...
32 CFR 1290.2 - Purpose and scope.
Code of Federal Regulations, 2013 CFR
2013-07-01
... National Defense Other Regulations Relating to National Defense DEFENSE LOGISTICS AGENCY MISCELLANEOUS... Federal Magistrate System by DLA. This part 1290 is applicable to HQ DLA, Defense Supply Centers (DSC's), less Defense Fuel Supply Center and Defense Industrial Supply Center, and to Defense Depots, less...
32 CFR 1290.2 - Purpose and scope.
Code of Federal Regulations, 2012 CFR
2012-07-01
... National Defense Other Regulations Relating to National Defense DEFENSE LOGISTICS AGENCY MISCELLANEOUS... Federal Magistrate System by DLA. This part 1290 is applicable to HQ DLA, Defense Supply Centers (DSC's), less Defense Fuel Supply Center and Defense Industrial Supply Center, and to Defense Depots, less...
32 CFR 1290.2 - Purpose and scope.
Code of Federal Regulations, 2011 CFR
2011-07-01
... National Defense Other Regulations Relating to National Defense DEFENSE LOGISTICS AGENCY MISCELLANEOUS... Federal Magistrate System by DLA. This part 1290 is applicable to HQ DLA, Defense Supply Centers (DSC's), less Defense Fuel Supply Center and Defense Industrial Supply Center, and to Defense Depots, less...
32 CFR 1290.2 - Purpose and scope.
Code of Federal Regulations, 2014 CFR
2014-07-01
... National Defense Other Regulations Relating to National Defense DEFENSE LOGISTICS AGENCY MISCELLANEOUS... Federal Magistrate System by DLA. This part 1290 is applicable to HQ DLA, Defense Supply Centers (DSC's), less Defense Fuel Supply Center and Defense Industrial Supply Center, and to Defense Depots, less...
Engineering Safety- and Security-Related Requirements for Software-Intensive Systems
2010-04-27
Requirements Negative (shall not) Requirements Hardware Requirements equ remen s System / Documentation Requirements eve oper Requirements Operational ...Validation Actual / Proposed Defensibility C li Operational Vulnerability Analysis VulnerabilityVulnerability Safety Vulnerability performs System ...including suggestions for reducing this burden, to Washington Headquarters Services, Directorate for Information Operations and Reports, 1215 Jefferson
Nahar, Kamrun; Kyndt, Tina; De Vleesschauwer, David; Höfte, Monica; Gheysen, Godelieve
2011-01-01
Complex defense signaling pathways, controlled by different hormones, are involved in the reaction of plants to a wide range of biotic and abiotic stress factors. We studied the ability of salicylic acid, jasmonate (JA), and ethylene (ET) to induce systemic defense in rice (Oryza sativa) against the root knot nematode Meloidogyne graminicola. Exogenous ET (ethephon) and JA (methyl jasmonate) supply on the shoots induced a strong systemic defense response in the roots, exemplified by a major up-regulation of pathogenesis-related genes OsPR1a and OsPR1b, while the salicylic acid analog BTH (benzo-1,2,3-thiadiazole-7-carbothioic acid S-methyl ester) was a less potent systemic defense inducer from shoot to root. Experiments with JA biosynthesis mutants and ET-insensitive transgenics showed that ET-induced defense requires an intact JA pathway, while JA-induced defense was still functional when ET signaling was impaired. Pharmacological inhibition of JA and ET biosynthesis confirmed that JA biosynthesis is needed for ET-induced systemic defense, and quantitative real-time reverse transcription-polymerase chain reaction data revealed that ET application onto the shoots strongly activates JA biosynthesis and signaling genes in the roots. All data provided in this study point to the JA pathway to play a pivotal role in rice defense against root knot nematodes. The expression of defense-related genes was monitored in root galls caused by M. graminicola. Different analyzed defense genes were attenuated in root galls caused by the nematode at early time points after infection. However, when the exogenous defense inducers ethephon and methyl jasmonate were supplied to the plant, the nematode was less effective in counteracting root defense pathways, hence making the plant more resistant to nematode infection. PMID:21715672
RNase H As Gene Modifier, Driver of Evolution and Antiviral Defense.
Moelling, Karin; Broecker, Felix; Russo, Giancarlo; Sunagawa, Shinichi
2017-01-01
Retroviral infections are 'mini-symbiotic' events supplying recipient cells with sequences for viral replication, including the reverse transcriptase (RT) and ribonuclease H (RNase H). These proteins and other viral or cellular sequences can provide novel cellular functions including immune defense mechanisms. Their high error rate renders RT-RNases H drivers of evolutionary innovation. Integrated retroviruses and the related transposable elements (TEs) have existed for at least 150 million years, constitute up to 80% of eukaryotic genomes and are also present in prokaryotes. Endogenous retroviruses regulate host genes, have provided novel genes including the syncytins that mediate maternal-fetal immune tolerance and can be experimentally rendered infectious again. The RT and the RNase H are among the most ancient and abundant protein folds. RNases H may have evolved from ribozymes, related to viroids, early in the RNA world, forming ribosomes, RNA replicases and polymerases. Basic RNA-binding peptides enhance ribozyme catalysis. RT and ribozymes or RNases H are present today in bacterial group II introns, the precedents of TEs. Thousands of unique RTs and RNases H are present in eukaryotes, bacteria, and viruses. These enzymes mediate viral and cellular replication and antiviral defense in eukaryotes and prokaryotes, splicing, R-loop resolvation, DNA repair. RNase H-like activities are also required for the activity of small regulatory RNAs. The retroviral replication components share striking similarities with the RNA-induced silencing complex (RISC), the prokaryotic CRISPR-Cas machinery, eukaryotic V(D)J recombination and interferon systems. Viruses supply antiviral defense tools to cellular organisms. TEs are the evolutionary origin of siRNA and miRNA genes that, through RISC, counteract detrimental activities of TEs and chromosomal instability. Moreover, piRNAs, implicated in transgenerational inheritance, suppress TEs in germ cells. Thus, virtually all known immune defense mechanisms against viruses, phages, TEs, and extracellular pathogens require RNase H-like enzymes. Analogous to the prokaryotic CRISPR-Cas anti-phage defense possibly originating from TEs termed casposons, endogenized retroviruses ERVs and amplified TEs can be regarded as related forms of inheritable immunity in eukaryotes. This survey suggests that RNase H-like activities of retroviruses, TEs, and phages, have built up innate and adaptive immune systems throughout all domains of life.
77 FR 69444 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2012-11-19
..., Defense Finance and Accounting Service, Freedom of Information/Privacy Act Program Manager, Corporate...; System of Records AGENCY: Defense Finance and Accounting Service, DoD. ACTION: Notice to amend a system of records. SUMMARY: The Defense Finance and Accounting Service is amending a system of records...
78 FR 41917 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2013-07-12
...; System of Records AGENCY: Defense Finance and Accounting Service, DoD. ACTION: Notice to amend a System of Records. SUMMARY: The Defense Finance and Accounting Service is amending a system of records...: Mr. Gregory Outlaw, (317) 510-4591. SUPPLEMENTARY INFORMATION: The Defense Finance and Accounting...
Secured network sensor-based defense system
NASA Astrophysics Data System (ADS)
Wei, Sixiao; Shen, Dan; Ge, Linqiang; Yu, Wei; Blasch, Erik P.; Pham, Khanh D.; Chen, Genshe
2015-05-01
Network sensor-based defense (NSD) systems have been widely used to defend against cyber threats. Nonetheless, if the adversary finds ways to identify the location of monitor sensors, the effectiveness of NSD systems can be reduced. In this paper, we propose both temporal and spatial perturbation based defense mechanisms to secure NSD systems and make the monitor sensor invisible to the adversary. The temporal-perturbation based defense manipulates the timing information of published data so that the probability of successfully recognizing monitor sensors can be reduced. The spatial-perturbation based defense dynamically redeploys monitor sensors in the network so that the adversary cannot obtain the complete information to recognize all of the monitor sensors. We carried out experiments using real-world traffic traces to evaluate the effectiveness of our proposed defense mechanisms. Our data shows that our proposed defense mechanisms can reduce the attack accuracy of recognizing detection sensors.
Code of Federal Regulations, 2010 CFR
2010-01-01
... between the performance management system and DoD's strategic plan; (4) A means for ensuring employee... Administrative Personnel DEPARTMENT OF DEFENSE HUMAN RESOURCES MANAGEMENT AND LABOR RELATIONS SYSTEMS (DEPARTMENT OF DEFENSE-OFFICE OF PERSONNEL MANAGEMENT) DEPARTMENT OF DEFENSE NATIONAL SECURITY PERSONNEL SYSTEM...
Code of Federal Regulations, 2011 CFR
2011-01-01
... between the performance management system and DoD's strategic plan; (4) A means for ensuring employee... Administrative Personnel DEPARTMENT OF DEFENSE HUMAN RESOURCES MANAGEMENT AND LABOR RELATIONS SYSTEMS (DEPARTMENT OF DEFENSE-OFFICE OF PERSONNEL MANAGEMENT) DEPARTMENT OF DEFENSE NATIONAL SECURITY PERSONNEL SYSTEM...
Code of Federal Regulations, 2013 CFR
2013-07-01
... Department of Defense OFFICE OF THE SECRETARY OF DEFENSE CIVIL DEFENSE DEFENSE SUPPORT OF CIVILIAN LAW... provides procedures for DoD support to Federal, State, Tribal, and local civilian law enforcement agencies, including responses to civil disturbances within the United States, including the District of Columbia, the...
75 FR 81247 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2010-12-27
...; System of Records AGENCY: Defense Intelligence Agency, DoD. ACTION: Notice to delete a system of records. SUMMARY: The Defense Intelligence Agency proposes to delete a system of records notice in its existing... Defense Intelligence Agency systems of records notices subject to the Privacy Act of 1974, (5 U.S.C. 552a...
75 FR 13089 - Privacy Act of 1974; Systems of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2010-03-18
...; Systems of Records AGENCY: Defense Intelligence Agency, (DoD). ACTION: Notice to amend a system of records. SUMMARY: The Defense Intelligence Agency proposes to amend a system of records notice of its inventory of... INFORMATION: The Defense Intelligence Agency notices for systems of records subject to the Privacy Act of 1974...
77 FR 26260 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2012-05-03
...; System of Records AGENCY: Defense Intelligence Agency, DoD. ACTION: Notice to Delete a System of Records. SUMMARY: The Defense Intelligence Agency proposes to delete a system of records notice in its existing...: The Defense Intelligence Agency systems of records notices subject to the Privacy Act of 1974 (5 U.S.C...
76 FR 10010 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2011-02-23
...; System of Records AGENCY: Defense Intelligence Agency, DoD. ACTION: Notice to Delete a System of Records. SUMMARY: The Defense Intelligence Agency proposes to delete a system of records notice in its existing... Defense Intelligence Agency systems of records notices subject to the Privacy Act of 1974, (5 U.S.C. 552a...
75 FR 33791 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2010-06-15
...; System of Records AGENCY: Defense Intelligence Agency, DoD. ACTION: Notice to add a system of records. SUMMARY: The Defense Intelligence Agency proposes to add a system of records to its inventory of record...: The Defense Intelligence Agency systems of records notices subject to the Privacy Act of 1974, (5 U.S...
78 FR 14282 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2013-03-05
...; System of Records AGENCY: Defense Contract Audit Agency, DoD. ACTION: Notice to alter a System of Records. SUMMARY: The Defense Contract Audit Agency proposes to alter a system of records in its inventory of.... SUPPLEMENTARY INFORMATION: The Defense Contract Audit Agency notices for systems of records subject to the...
76 FR 115 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2011-01-03
...; System of Records AGENCY: Defense Contract Audit Agency, DoD. ACTION: Notice to amend a system of records. SUMMARY: The Defense Contract Audit Agency is proposing to amend a system of records notice in its... INFORMATION: The Defense Contract Audit Agency systems of records notices subject to the Privacy Act of 1974...
76 FR 114 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2011-01-03
...; System of Records AGENCY: Defense Contract Audit Agency, DoD. ACTION: Notice to amend a system of records. SUMMARY: The Defense Contract Audit Agency is proposing to amend a system of records notice in its... INFORMATION: The Defense Contract Audit Agency systems of records notices subject to the Privacy Act of 1974...
78 FR 14284 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2013-03-05
...; System of Records AGENCY: Defense Contract Audit Agency, DoD. ACTION: Notice to alter a System of Records. SUMMARY: The Defense Contract Audit Agency proposes to alter a system of records in its inventory of.... SUPPLEMENTARY INFORMATION: The Defense Contract Audit Agency notices for systems of records subject to the...
78 FR 47309 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2013-08-05
...; System of Records AGENCY: Defense Finance and Accounting Service, DoD. ACTION: Notice to amend a System of Records. SUMMARY: The Defense Finance and Accounting Service proposes to alter a system of records... Defense Finance and Accounting Service systems of records notices subject to the Privacy Act of 1974 (5 U...
75 FR 33788 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2010-06-15
... Allard at (703) 588-6830. SUPPLEMENTARY INFORMATION: The Office of the Secretary of Defense systems of...; System of Records AGENCY: Department of Defense, DoD. ACTION: Notice to delete a system of records. SUMMARY: The Office of the Secretary of Defense proposes to delete a systems of record notice from its...
77 FR 25991 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2012-05-02
... DEPARTMENT OF DEFENSE Department of the Army [Docket ID: USA-2012-0008] Privacy Act of 1974; System of Records AGENCY: Defense Information Systems Agency, DoD. ACTION: Notice to Add a New System of... Federal Register Liaison Officer, Department of Defense. A0350-1 ARNG System name: Guard University (Guard...
75 FR 76430 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2010-12-08
... DEPARTMENT OF DEFENSE Office of the Secretary [Docket ID DOD-2010-OS-0159] Privacy Act of 1974.... Park, Alternate OSD Federal Register Liaison Officer, Department of Defense. DWHS P37 * * * * * SYSTEM... Headquarters Services, Department of Defense, 1155 Defense Pentagon, Washington, DC 20301-1155.'' CATEGORIES OF...
76 FR 58788 - Privacy Act of 1974; Systems of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2011-09-22
... Manager, Corporate Communications, Defense Finance and Accounting Service, DFAS-HKC/IN, 8899 E. 56th... inquires to FOIA/PA Program Manager, Corporate Communications, Defense Finance and Accounting Service, DFAS...; Systems of Records AGENCY: Defense Finance and Accounting Service, Department of Defense, (DoD). ACTION...
Code of Federal Regulations, 2010 CFR
2010-01-01
... Administrative Personnel DEPARTMENT OF DEFENSE HUMAN RESOURCES MANAGEMENT AND LABOR RELATIONS SYSTEMS (DEPARTMENT OF DEFENSE-OFFICE OF PERSONNEL MANAGEMENT) DEPARTMENT OF DEFENSE NATIONAL SECURITY PERSONNEL SYSTEM... supports mission accomplishment. ...
Code of Federal Regulations, 2011 CFR
2011-01-01
... Administrative Personnel DEPARTMENT OF DEFENSE HUMAN RESOURCES MANAGEMENT AND LABOR RELATIONS SYSTEMS (DEPARTMENT OF DEFENSE-OFFICE OF PERSONNEL MANAGEMENT) DEPARTMENT OF DEFENSE NATIONAL SECURITY PERSONNEL SYSTEM... supports mission accomplishment. ...
Defense Enterprise Accounting and Management System-Increment 1 (DEAMS Inc 1)
2016-03-01
information accurately and in conformance with Generally Accepted Accounting Principles , to comply with Congressional requirements of the Chief Financial ...2016 Major Automated Information System Annual Report Defense Enterprise Accounting and Management System-Increment 1 (DEAMS Inc 1) Defense...Phone: 937-257-2714 Fax: DSN Phone: 787-2714 DSN Fax: Date Assigned: August 17, 2015 Program Information Program Name Defense Enterprise Accounting
Monoterpenes Support Systemic Acquired Resistance within and between Plants
Ghirardo, Andrea; Knappe, Claudia; Koch, Kerstin; Dey, Sanjukta; Parker, Jane E.
2017-01-01
This study investigates the role of volatile organic compounds in systemic acquired resistance (SAR), a salicylic acid (SA)-associated, broad-spectrum immune response in systemic, healthy tissues of locally infected plants. Gas chromatography coupled to mass spectrometry analyses of SAR-related emissions of wild-type and non-SAR-signal-producing mutant plants associated SAR with monoterpene emissions. Headspace exposure of Arabidopsis thaliana to a mixture of the bicyclic monoterpenes α-pinene and β-pinene induced defense, accumulation of reactive oxygen species, and expression of SA- and SAR-related genes, including the SAR regulatory AZELAIC ACID INDUCED1 (AZI1) gene and three of its paralogs. Pinene-induced resistance was dependent on SA biosynthesis and signaling and on AZI1. Arabidopsis geranylgeranyl reductase1 mutants with reduced monoterpene biosynthesis were SAR-defective but mounted normal local resistance and methyl salicylate-induced defense responses, suggesting that monoterpenes act in parallel with SA. The volatile emissions from SAR signal-emitting plants induced defense in neighboring plants, and this was associated with the presence of α-pinene, β-pinene, and camphene in the emissions of the “sender” plants. Our data suggest that monoterpenes, particularly pinenes, promote SAR, acting through ROS and AZI1, and likely function as infochemicals in plant-to-plant signaling, thus allowing defense signal propagation between neighboring plants. PMID:28536145
Code of Federal Regulations, 2014 CFR
2014-07-01
... Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) MISCELLANEOUS... Defense (OSD), the Military Departments (including their National Guard and Reserve components), the Unified and Specified Commands, the Defense Agencies, and Department of Defense Field Activities...
32 CFR 634.44 - The traffic point system.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 32 National Defense 4 2010-07-01 2010-07-01 true The traffic point system. 634.44 Section 634.44 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY (CONTINUED) LAW ENFORCEMENT AND... § 634.44 The traffic point system. The traffic point system provides a uniform administrative device to...
75 FR 61450 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2010-10-05
..., Corporate Communications, Defense Finance and Accounting Service, DFAS-HKC/IN, 8899 E. 56th Avenue...; System of Records AGENCY: Defense Finance and Accounting Service; DoD. ACTION: Notice to add a system of records. SUMMARY: The Defense Finance and Accounting Service (DFAS) is proposing to add a system of...
75 FR 36640 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2010-06-28
... DEPARTMENT OF DEFENSE Office of the Secretary [Docket ID: DOD-2010-OS-0085] Privacy Act of 1974; System of Records AGENCY: Department of Defense (DoD). ACTION: Notice to alter a system of records... Liaison Officer, Department of Defense. DWHS D01 System name: Pentagon Parking/national Capital Region...
75 FR 63160 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2010-10-14
... DEPARTMENT OF DEFENSE Office of the Secretary [Docket ID DOD-2010-OS-0142] Privacy Act of 1974; System of Records AGENCY: Department of Defense (DoD). ACTION: Notice to alter a system of records... Federal Register Liaison Officer, Department of Defense. DWHS E05 System name: Mandatory Declassification...
78 FR 6077 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2013-01-29
... DEPARTMENT OF DEFENSE Office of the Secretary [Docket ID: DoD-2013-OS-0009] Privacy Act of 1974; System of Records AGENCY: Defense Security Service, DoD. ACTION: Notice to amend a System of Records... OSD Federal Register Liaison Officer, Department of Defense. V5-04 System name: Counterintelligence...
77 FR 34357 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2012-06-11
... DEPARTMENT OF DEFENSE Office of the Secretary [Docket ID: DOD-2012-OS-0062] Privacy Act of 1974; System of Records AGENCY: Defense Information Systems Agency, DoD. ACTION: Notice to alter a system of..., 2012. Aaron Siegel, Alternate OSD Federal Register Liaison Officer, Department of Defense. K890.01...
32 CFR 635.27 - Vehicle Registration System.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 32 National Defense 4 2010-07-01 2010-07-01 true Vehicle Registration System. 635.27 Section 635.27 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY (CONTINUED) LAW ENFORCEMENT AND CRIMINAL INVESTIGATIONS LAW ENFORCEMENT REPORTING Offense Reporting § 635.27 Vehicle Registration System. The Vehicle Registration System (VR...
32 CFR 310.32 - System notices.
Code of Federal Regulations, 2012 CFR
2012-07-01
... Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) PRIVACY PROGRAM DOD PRIVACY PROGRAM Publication Requirements § 310.32 System notices. (a) Contents of the system... database or the IT system if the name does not meet the criteria in paragraph (c)(1) of this section. (d...
32 CFR 310.32 - System notices.
Code of Federal Regulations, 2014 CFR
2014-07-01
... Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) PRIVACY PROGRAM DOD PRIVACY PROGRAM Publication Requirements § 310.32 System notices. (a) Contents of the system... database or the IT system if the name does not meet the criteria in paragraph (c)(1) of this section. (d...
32 CFR 310.32 - System notices.
Code of Federal Regulations, 2013 CFR
2013-07-01
... Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) PRIVACY PROGRAM DOD PRIVACY PROGRAM Publication Requirements § 310.32 System notices. (a) Contents of the system... database or the IT system if the name does not meet the criteria in paragraph (c)(1) of this section. (d...
76 FR 24000 - Privacy Act of 1974; Systems of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2011-04-29
...; Systems of Records AGENCY: Defense Logistics Agency, DoD. ACTION: Notice to add a system of records. SUMMARY: The Defense Logistics Agency proposes to add a system of records notice to its existing inventory... Act Officer, Headquarters, Defense Logistics Agency, Attn: DGA, 8725 John J. Kingman Road, Stop 16443...
76 FR 20339 - Privacy Act of 1974; Systems of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2011-04-12
...; Systems of Records AGENCY: Defense Logistics Agency, DoD. ACTION: Notice to Alter a System of Records. SUMMARY: The Defense Logistics Agency proposes to alter a system of records notice in its existing... Officer, Headquarters, Defense Logistics Agency, Attn: DGA, 8725 John J. Kingman Road, Stop 16443, Fort...
77 FR 26258 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2012-05-03
...; System of Records AGENCY: Defense Intelligence Agency, DoD. ACTION: Notice to Alter a System of Records. SUMMARY: The Defense Intelligence Agency is proposing to alter a system to its existing inventory of... identifiers or contact information. FOR FURTHER INFORMATION CONTACT: Ms. Theresa Lowery, Defense Intelligence...
78 FR 47308 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2013-08-05
...; System of Records AGENCY: Defense Intelligence Agency, DoD. ACTION: Notice to alter a System of Records. SUMMARY: The Defense Intelligence Agency is proposing to alter a system of records in its existing.... FOR FURTHER INFORMATION CONTACT: Ms. Theresa Lowery at Defense Intelligence Agency, DAN 1-C, 600...
78 FR 22524 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2013-04-16
...; System of Records AGENCY: Defense Intelligence Agency, DoD. ACTION: Notice to alter a System of Records. SUMMARY: The Defense Intelligence Agency is proposing to alter a system to its existing inventory of.... FOR FURTHER INFORMATION CONTACT: Ms. Theresa Lowery at Defense Intelligence Agency, DAN 1-C, 600...
76 FR 35191 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2011-06-16
...; System of Records AGENCY: Defense Intelligence Agency, DoD. ACTION: Notice to alter a system of records. SUMMARY: The Defense Intelligence Agency is proposing to alter a system to its existing inventory of...: Ms. Theresa Lowery, Defense Intelligence Agency, DAN 1-C, 600 McDill Blvd., Washington, DC 20340...
77 FR 57077 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2012-09-17
...; System of Records AGENCY: Defense Intelligence Agency, DoD. ACTION: Notice to Add a System of Records. SUMMARY: The Defense Intelligence Agency is proposing the add a system to its existing inventory of... information. FOR FURTHER INFORMATION CONTACT: Ms. Theresa Lowery at Defense Intelligence Agency, DAN 1-C, 600...
77 FR 26262 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2012-05-03
...; System of Records AGENCY: Defense Intelligence Agency, DoD. ACTION: Notice to alter a system of records. SUMMARY: The Defense Intelligence Agency is proposing to alter a system to its existing inventory of.... FOR FURTHER INFORMATION CONTACT: Ms. Theresa Lowery. Defense Intelligence Agency, DAN 1-C, 600 McDill...
78 FR 5787 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2013-01-28
...; System of Records AGENCY: Defense Intelligence Agency, DoD. ACTION: Notice to alter a System of Records. SUMMARY: The Defense Intelligence Agency is proposing to alter a system to its existing inventory of.... FOR FURTHER INFORMATION CONTACT: Ms. Theresa Lowery at Defense Intelligence Agency, DAN 1-C, 600...
77 FR 26256 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2012-05-03
...; System of Records AGENCY: Defense Intelligence Agency, DoD. ACTION: Notice to Alter a System of Records. SUMMARY: The Defense Intelligence Agency is proposing to alter a system to its existing inventory of.... FOR FURTHER INFORMATION CONTACT: Ms. Theresa Lowery, Defense Intelligence Agency, DAN 1-C, 600 McDill...
78 FR 41916 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2013-07-12
... Defense Finance and Accounting Service, Freedom of Information/Privacy Act Program Manager, Corporate...; System of Records AGENCY: Defense Finance and Accounting Service, DoD. ACTION: Notice to alter a System of Records. SUMMARY: The Defense Finance and Accounting Service proposes to alter a system of records...
76 FR 52322 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2011-08-22
...; System of Records AGENCY: Office of the Secretary of Defense, Department of Defense (DoD). ACTION: Notice to delete a System of Records. SUMMARY: The Office of the Secretary of Defense (Office of Assistant General Counsel, Manpower and Health Affairs) is deleting systems of records notice from its existing...
75 FR 32416 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2010-06-08
... DEPARTMENT OF DEFENSE Office of the Secretary [Docket ID: DOD-2010-OS-0075] Privacy Act of 1974; System of Records AGENCY: Department of Defense (DoD). ACTION: Notice to amend a system of records.... Mitchell S. Bryman, Alternate OSD Federal Register Liaison Officer, Department of Defense. WUSU 07 System...
77 FR 26261 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2012-05-03
...; System of Records AGENCY: Office of the Defense Logistics Agency, DoD. ACTION: Notice to alter a system of records. SUMMARY: The Defense Logistics Agency proposes to alter a system of records in its.../Privacy Act Office, Headquarters, Defense Logistics Agency, ATTN: DGA, 8725 John J. Kingman Road, Suite...
32 CFR 701.129 - Exemptions for specific Marine Corps record systems.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 32 National Defense 5 2013-07-01 2013-07-01 false Exemptions for specific Marine Corps record systems. 701.129 Section 701.129 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY... Exemptions for specific Marine Corps record systems. (a) [Reserved] (b) System identifier and name: (1...
32 CFR 701.129 - Exemptions for specific Marine Corps record systems.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 32 National Defense 5 2012-07-01 2012-07-01 false Exemptions for specific Marine Corps record systems. 701.129 Section 701.129 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY... Exemptions for specific Marine Corps record systems. (a) [Reserved] (b) System identifier and name: (1...
76 FR 20341 - Privacy Act of 1974; Systems of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2011-04-12
...; Systems of Records AGENCY: Defense Logistics Agency, DoD. ACTION: Notice to alter a system of records. SUMMARY: The Defense Logistics Agency proposes to alter a system of records notice in its existing... Officer, Headquarters, Defense Logistics Agency, Attn: DGA, 8725 John J. Kingman Road, Stop 16443, Fort...
76 FR 12078 - Privacy Act of 1974; Systems of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2011-03-04
...; Systems of Records AGENCY: Defense Logistics Agency. ACTION: Notice to alter a system of records. SUMMARY: The Defense Logistics Agency proposes to alter a system of records notice in its existing inventory of... Act Officer, Headquarters, Defense Logistics Agency, Attn: DGA, 8725 John J. Kingman Road, Stop 16443...
76 FR 13991 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2011-03-15
...; System of Records AGENCY: Defense Logistics Agency, DoD. ACTION: Notice to amend a system of records. SUMMARY: The Defense Logistics Agency is proposing to amend a system of records notice in its existing...-5045, or the Privacy Act Officer, Headquarters Defense Logistics Agency, ATTN: DGA, 8725 John J...
76 FR 28002 - Privacy Act of 1974; Systems of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2011-05-13
...; Systems of Records AGENCY: Defense Logistics Agency, DoD. ACTION: Notice to delete three systems of records. SUMMARY: The Defense Logistics Agency proposes to delete three systems of records notices in its..., Headquarters Defense Logistics Agency, ATTN: DGA, 8725 John J. Kingman Road, Suite 1644, Fort Belvoir, VA 22060...
76 FR 12076 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2011-03-04
...; System of Records AGENCY: Defense Logistics Agency, DoD. ACTION: Notice to amend a system of records. SUMMARY: The Defense Logistics Agency is proposing to amend a system of records notice in its existing...-5045, or Privacy Act Officer, Headquarters Defense Logistics Agency, ATTN: DGA, 8725 John J. Kingman...
Ali, Shawkat; Magne, Maxime; Chen, Shiyan; Obradovic, Natasa; Jamshaid, Lubna; Wang, Xiaohong; Bélair, Guy; Moffett, Peter
2015-01-01
Potato cyst nematodes (PCNs), including Globodera rostochiensis (Woll.), are important pests of potato. Plant parasitic nematodes produce multiple effector proteins, secreted from their stylets, to successfully infect their hosts. These include proteins delivered to the apoplast and to the host cytoplasm. A number of effectors from G. rostochiensis predicted to be delivered to the host cytoplasm have been identified, including several belonging to the secreted SPRY domain (SPRYSEC) family. SPRYSEC proteins are unique to members of the genus Globodera and have been implicated in both the induction and the repression of host defense responses. We have tested the properties of six different G. rostochiensis SPRYSEC proteins by expressing them in Nicotiana benthamiana and N. tabacum. We have found that all SPRYSEC proteins tested are able to suppress defense responses induced by NB-LRR proteins as well as cell death induced by elicitors, suggesting that defense repression is a common characteristic of members of this effector protein family. At the same time, GrSPRYSEC-15 elicited a defense responses in N. tabacum, which was found to be resistant to a virus expressing GrSPRYSEC-15. These results suggest that SPRYSEC proteins may possess characteristics that allow them to be recognized by the plant immune system.
75 FR 78619 - Defense Federal Acquisition Regulation Supplement; Technical Amendments
Federal Register 2010, 2011, 2012, 2013, 2014
2010-12-16
... DEPARTMENT OF DEFENSE Defense Acquisition Regulations System 48 CFR Parts 216 and 237 Defense Federal Acquisition Regulation Supplement; Technical Amendments AGENCY: Defense Acquisition Regulations... the Defense Federal Acquisition Regulation Supplement (DFARS) to set forth references to supplementary...
Sandia National Laboratories: National Security Missions: Defense Systems
; Technology Defense Systems & Assessments About Defense Systems & Assessments Program Areas Robotics R&D 100 Awards Laboratory Directed Research & Development Technology Deployment Centers Audit Sandia's Economic Impact Licensing & Technology Transfer Browse Technology Portfolios
Federal Register 2010, 2011, 2012, 2013, 2014
2013-04-01
... DEPARTMENT OF DEFENSE Defense Acquisition Regulations System [Docket Number DARS-2013-0010... Mentor-Prot[eacute]g[eacute] Program AGENCY: Defense Acquisition Regulations System, Department of... Collection DFARS Appendix I-112.2(a)-(d) requires mentor firms to report on the progress made under active...
Natural History of Innate Host Defense Peptides.
Linde, A; Wachter, B; Höner, O P; Dib, L; Ross, C; Tamayo, A R; Blecha, F; Melgarejo, T
2009-12-01
Host defense peptides act on the forefront of innate immunity, thus playing a central role in the survival of animals and plants. Despite vast morphological changes in species through evolutionary history, all animals examined to date share common features in their innate immune defense strategies, hereunder expression of host defense peptides (HDPs). Most studies on HDPs have focused on humans, domestic and laboratory animals. More than a thousand different sequences have been identified, yet data on HDPs in wild-living animals are sparse. The biological functions of HDPs include broad-spectrum antimicrobial activity and immunomodulation. Natural selection and coevolutionary host-pathogen arms race theory suggest that the extent and specificity of the microbial load influences the spectrum and potency of HDPs in different species. Individuals of extant species-that have lived for an extended period in evolutionary history amid populations with intact processes of natural selection-likely possess the most powerful and well-adapted "natural antibiotics". Research on the evolutionary history of the innate defense system and the host in context of the consequences of challenges as well as the efficacy of the innate immune system under natural conditions is therefore of immediate interest. This review focuses on evolutionary aspects of immunophysiology, with emphasis on innate effector molecules. Studies on host defense in wild-living animals may significantly enhance our understanding of inborn immune mechanisms, and help identify molecules that may assist us to cope better with the increasing microbial challenges that likely follow from the continuous amplification of biodiversity levels on Earth.
The Science and Technology of the US National Missile Defense System
NASA Astrophysics Data System (ADS)
Postol, Theodore A.
2010-03-01
The National Missile Defense System utilizes UHF and X-band radars for search, track and discrimination, and interceptors that use long-wave infrared sensors to identify and home on attacking warheads. The radars and infrared sensors in the missile defense system perform at near the theoretical limits predicted by physics. However, in spite of the fantastic technical advances in sensor technology, signal processing, and computational support functions, the National Missile Defense System cannot be expected to ever work in realistic combat environments. This talk will describe why these impressive technologies can never deliver on the promise of a credible defense against long-range ballistic missiles.
Code of Federal Regulations, 2010 CFR
2010-10-01
... DEFENSE ACQUISITION PLANNING DESCRIBING AGENCY NEEDS 211.002 Policy. All defense technology and... System, and DoDI 5000.2, Operation of the Defense Acquisition System. [71 FR 27641, May 12, 2006] ...
Secure VM for Monitoring Industrial Process Controllers
DOE Office of Scientific and Technical Information (OSTI.GOV)
Dasgupta, Dipankar; Ali, Mohammad Hassan; Abercrombie, Robert K
2011-01-01
In this paper, we examine the biological immune system as an autonomic system for self-protection, which has evolved over millions of years probably through extensive redesigning, testing, tuning and optimization process. The powerful information processing capabilities of the immune system, such as feature extraction, pattern recognition, learning, memory, and its distributive nature provide rich metaphors for its artificial counterpart. Our study focuses on building an autonomic defense system, using some immunological metaphors for information gathering, analyzing, decision making and launching threat and attack responses. In order to detection Stuxnet like malware, we propose to include a secure VM (or dedicatedmore » host) to the SCADA Network to monitor behavior and all software updates. This on-going research effort is not to mimic the nature but to explore and learn valuable lessons useful for self-adaptive cyber defense systems.« less
Endogenous small RNAs and antibacterial immunity in plants.
Jin, Hailing
2008-08-06
Small RNAs are non-coding regulatory RNA molecules that control gene expression by mediating mRNA degradation, translational inhibition, or chromatin modification. Virus-derived small RNAs induce silencing of viral RNAs and are essential for antiviral defense in both animal and plant systems. The role of host endogenous small RNAs on antibacterial immunity has only recently been recognized. Host disease resistance and defense responses are achieved by activation and repression of a large array of genes. Certain endogenous small RNAs in plants, including microRNAs (miRNAs) and small interfering RNAs (siRNAs), are induced or repressed in response to pathogen attack and subsequently regulate the expression of genes involved in disease resistance and defense responses by mediating transcriptional or post-transcriptional gene silencing. Thus, these small RNAs play an important role in gene expression reprogramming in plant disease resistance and defense responses. This review focuses on the recent findings of plant endogenous small RNAs in antibacterial immunity.
Transgenerational Effects Alter Plant Defense and Resistance in Nature
Colicchio, Jack
2017-01-01
Trichomes, or leaf hairs, are epidermal extensions that take a variety of forms and perform many functions in plants, including herbivore defense. In this study, I document genetically determined variation, within-generation plasticity, and a direct role of trichomes in herbivore defense for Mimulus guttatus. After establishing the relationship between trichomes and herbivory, I test for transgenerational effects of wounding on trichome density and herbivore resistance. Patterns of inter-annual variation in herbivore density and the high cost of plant defense makes plant-herbivore interactions a system in which transgenerational phenotypic plasticity (TPP) is apt to evolve. Here, I demonstrate that parental damage alters offspring trichome density and herbivore resistance in nature. Moreover, this response varies between populations. This is among the first studies to demonstrate that TPP contributes to variation in nature, and also suggests that selection can modify TPP in response to local conditions. PMID:28102915
78 FR 15711 - Submission for OMB Review; Comment Request
Federal Register 2010, 2011, 2012, 2013, 2014
2013-03-12
... use to determine if contractor material management and accounting systems conform to established DoD... DEPARTMENT OF DEFENSE Defense Acquisition Regulation System [Docket No. 2012-0044-0001] Submission for OMB Review; Comment Request ACTION: Notice. The Defense Acquisition Regulations System has...
Component Composition for Embedded Systems Using Semantic Aspect-Oriented Programming
2004-10-01
real - time systems for the defense community. Our research focused on Real-Time Java implementation and analysis techniques. Real-Time Java is important for the defense community because it holds out the promise of enabling developers to apply COTS Java technology to specialized military embedded systems. It also promises to allow the defense community to utilize a large Java-literate workforce for building defense systems. Our research has delivered several techniques that may make Real-Time Java a better platform for developing embedded
2015-05-08
Defense Logistics Agency Did Not Obtain Fair and Reasonable Prices From Meggitt Aircraft Braking Systems for Sole-Source Commercial Spare Parts...Defense Logistics Agency Did Not Obtain Fair and Reasonable Prices From Meggitt Aircraft Braking Systems for Sole-Source Commercial Spare Parts...D000AH-0180.000) │ i Results in Brief Defense Logistics Agency Did Not Obtain Fair and Reasonable Prices From Meggitt Aircraft Braking Systems for
Density-dependent adjustment of inducible defenses.
Tollrian, Ralph; Duggen, Sonja; Weiss, Linda C; Laforsch, Christian; Kopp, Michael
2015-08-03
Predation is a major factor driving evolution, and organisms have evolved adaptations increasing their survival chances. However, most defenses incur trade-offs between benefits and costs. Many organisms save costs by employing inducible defenses as responses to fluctuating predation risk. The level of defense often increases with predator densities. However, individual predation risk should not only depend on predator density but also on the density of conspecifics. If the predator has a saturating functional response one would predict a negative correlation between prey density and individual predation risk and hence defense expression. Here, we tested this hypothesis using six model systems, covering a taxonomic range from protozoa to rotifers and crustaceans. In all six systems, we found that the level of defense expression increased with predator density but decreased with prey density. In one of our systems, i.e. in Daphnia, we further show that the response to prey density is triggered by a chemical cue released by conspecifics and congeners. Our results indicate that organisms adjust the degree of defense to the acute predation risk, rather than merely to predators' densities. Our study suggests that density-dependent defense expression reflects accurate predation-risk assessment and is a general principle in many inducible-defense systems.
Density-dependent adjustment of inducible defenses
Tollrian, Ralph; Duggen, Sonja; Weiss, Linda C.; Laforsch, Christian; Kopp, Michael
2015-01-01
Predation is a major factor driving evolution, and organisms have evolved adaptations increasing their survival chances. However, most defenses incur trade-offs between benefits and costs. Many organisms save costs by employing inducible defenses as responses to fluctuating predation risk. The level of defense often increases with predator densities. However, individual predation risk should not only depend on predator density but also on the density of conspecifics. If the predator has a saturating functional response one would predict a negative correlation between prey density and individual predation risk and hence defense expression. Here, we tested this hypothesis using six model systems, covering a taxonomic range from protozoa to rotifers and crustaceans. In all six systems, we found that the level of defense expression increased with predator density but decreased with prey density. In one of our systems, i.e. in Daphnia, we further show that the response to prey density is triggered by a chemical cue released by conspecifics and congeners. Our results indicate that organisms adjust the degree of defense to the acute predation risk, rather than merely to predators’ densities. Our study suggests that density-dependent defense expression reflects accurate predation-risk assessment and is a general principle in many inducible-defense systems. PMID:26235428
75 FR 16758 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2010-04-02
... DEPARTMENT OF DEFENSE Office of the Secretary [Docket ID: DoD-2010-OS-0036] Privacy Act of 1974; System of Records AGENCY: Defense Threat Reduction Agency, DoD. ACTION: Notice to amend a system of records. SUMMARY: The Defense Threat Reduction Agency proposes to amend a system of records notice in its...
77 FR 75621 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2012-12-21
... DEPARTMENT OF DEFENSE Office of the Secretary [Docket ID: DoD-2012-OS-0162] Privacy Act of 1974; System of Records AGENCY: Defense Contract Audit Agency, DoD. ACTION: Notice to amend a System of Records..., Department of Defense. RDCAA 215.1 System name: Voluntary Leave Transfer Program (January 31, 1997, 62 FR...
77 FR 3238 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2012-01-23
...; System of Records AGENCY: Defense Logistics Agency, DoD. ACTION: Notice To Amend a System of Records. SUMMARY: The Defense Logistics Agency is proposing to amend a system of records in its inventory of record... Office, Headquarters, Defense Logistics Agency, ATTN: DGA, 8725 John J. Kingman Road, Suite 1644, Fort...
76 FR 39390 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2011-07-06
...; System of Records AGENCY: Defense Logistics Agency, DoD. ACTION: Notice to amend a system of records. SUMMARY: The Defense Logistics Agency is proposing to amend a system of records notice in its existing... Defense Logistics Agency, ATTN: DGA, 8725 John J. Kingman Road, Suite 1644, Fort Belvoir, VA 22060-6221...
76 FR 65185 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2011-10-20
...; System of Records AGENCY: Defense Logistics Agency, Department of Defense. ACTION: Notice to amend a system of records. SUMMARY: The Defense Logistics Agency is proposing to amend a system of records notice... Logistics Agency, ATTN: DGA, 8725 John J. Kingman Road, Suite 1644, Fort Belvoir, VA 22060-6221, or by phone...
76 FR 72909 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2011-11-28
...; System of Records AGENCY: Defense Logistics Agency, Department of Defense (DoD). ACTION: Notice to amend a system of records. SUMMARY: The Defense Logistics Agency is proposing to amend a system of records... Office, 4800 Mark Center Drive, East Tower, 2nd Floor, Suite 02G09, Alexandria, VA 22350- 3100...
77 FR 57076 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2012-09-17
...; System of Records AGENCY: Defense Intelligence Agency, DoD. ACTION: Notice to alter a System of Records. SUMMARY: The Defense Intelligence Agency is proposing to alter a system to its existing inventory of...: Ms. Theresa Lowery at Defense Intelligence Agency, DAN 1-C, 600 MacDill Blvd., Washington, DC 20340...
77 FR 9632 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2012-02-17
...; System of Records AGENCY: Defense Logistics Agency, DoD. ACTION: Notice to Amend a System of Records. SUMMARY: The Defense Logistics Agency is proposing to amend a system of records in its inventory of record... Office, Headquarters, Defense Logistics Agency, ATTN: DGA, 8725 John J. Kingman Road, Suite 1644, Fort...
77 FR 38274 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2012-06-27
.... SUPPLEMENTARY INFORMATION: The Defense Security Service systems of records notices subject to the Privacy Act of... DEPARTMENT OF DEFENSE Office of the Secretary [Docket ID DOD-2012-OS-0077] Privacy Act of 1974; System of Records AGENCY: Defense Security Service, DoD. ACTION: Notice to Delete Four Systems of Records...
78 FR 22854 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2013-04-17
... DEPARTMENT OF DEFENSE Office of the Secretary [Docket ID: DoD-2013-OS-0075] Privacy Act of 1974; System of Records AGENCY: Defense Logistics Agency, DoD. ACTION: Notice to alter a System of Records... Officer, Department of Defense. S190.10 System name: DLA Hometown News Releases (June 24, 2011; 76 FR...
76 FR 37082 - Privacy Act of 1974; Systems of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2011-06-24
... DEPARTMENT OF DEFENSE Office of the Secretary [Docket ID: DOD-2011-OS-0068] Privacy Act of 1974; Systems of Records AGENCY: Defense Logistics Agency, DoD. ACTION: Notice To Amend a System of Records..., Alternate OSD Federal Register Liaison Officer, Department of Defense. S190.10 System name: DLA Hometown...
76 FR 11213 - Privacy Act of 1974; Systems of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2011-03-01
...; Systems of Records AGENCY: Defense Logistics Agency, DoD. ACTION: Notice to delete a system of records. SUMMARY: The Defense Logistics Agency proposes to delete a system of records notice in its existing..., Headquarters Defense Logistics Agency, Attn: DGA, 8725 John J. Kingman Road, Suite 1644, Fort Belvoir, VA 22060...
76 FR 26714 - Privacy Act of 1974; Systems of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2011-05-09
...; Systems of Records AGENCY: Defense Logistics Agency, DoD. ACTION: Notice to Delete a System of Records. SUMMARY: The Defense Logistics Agency proposes to delete a system of records notice in its existing..., Headquarters Defense Logistics Agency, ATTN: DGA, 8725 John J. Kingman Road, Suite 1644, Fort Belvoir, VA 22060...
76 FR 11213 - Privacy Act of 1974; Systems of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2011-03-01
...; Systems of Records AGENCY: Defense Logistics Agency, DoD. ACTION: Notice to delete a system of records. SUMMARY: The Defense Logistics Agency proposes to delete a system of records notice in its existing..., Headquarters Defense Logistics Agency, ATTN: DGA, 8725 John J. Kingman Road, Suite 1644, Fort Belvoir, VA 22060...
76 FR 76149 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2011-12-06
...; System of Records AGENCY: Defense Logistics Agency, DoD. ACTION: Notice to Amend a System of Records. SUMMARY: The Defense Logistics Agency is proposing to amend a system of records notice in its existing...: Ms. Jody Sinkler at (703) 767-5045, or DLA FOIA/Privacy Act Office, Headquarters, Defense Logistics...
75 FR 59102 - Defense Federal Acquisition Regulation Supplement; Part 204, Administrative Matters
Federal Register 2010, 2011, 2012, 2013, 2014
2010-09-27
... indexing methodology across DoD. This technical amendment adds language to the Defense Federal Acquisition... DEPARTMENT OF DEFENSE Defense Acquisition Regulations System 48 CFR Part 204 Defense Federal Acquisition Regulation Supplement; Part 204, Administrative Matters AGENCY: Defense Acquisition Regulations...
32 CFR 319.5 - Procedures for requests pertaining to individual records in a record system.
Code of Federal Regulations, 2012 CFR
2012-07-01
... OF THE SECRETARY OF DEFENSE (CONTINUED) PRIVACY PROGRAM DEFENSE INTELLIGENCE AGENCY PRIVACY PROGRAM... seeking notification of whether a system of records, maintained by the Defense Intelligence Agency... request to the Defense Intelligence Agency, DSP-1A, Washington, DC 20340-3299 and indicate clearly on the...
32 CFR 319.5 - Procedures for requests pertaining to individual records in a record system.
Code of Federal Regulations, 2010 CFR
2010-07-01
... OF THE SECRETARY OF DEFENSE (CONTINUED) PRIVACY PROGRAM DEFENSE INTELLIGENCE AGENCY PRIVACY PROGRAM... seeking notification of whether a system of records, maintained by the Defense Intelligence Agency... request to the Defense Intelligence Agency, DSP-1A, Washington, DC 20340-3299 and indicate clearly on the...
32 CFR 319.5 - Procedures for requests pertaining to individual records in a record system.
Code of Federal Regulations, 2014 CFR
2014-07-01
... OF THE SECRETARY OF DEFENSE (CONTINUED) PRIVACY PROGRAM DEFENSE INTELLIGENCE AGENCY PRIVACY PROGRAM... seeking notification of whether a system of records, maintained by the Defense Intelligence Agency... request to the Defense Intelligence Agency, DSP-1A, Washington, DC 20340-3299 and indicate clearly on the...
32 CFR 701.128 - Exemptions for specific Navy record systems.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 32 National Defense 5 2014-07-01 2014-07-01 false Exemptions for specific Navy record systems. 701.128 Section 701.128 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY UNITED... purposes by the Department of the Navy and the Department of Defense. [71 FR 27536, May 11, 2006, as...
Code of Federal Regulations, 2014 CFR
2014-10-01
... Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CLAUSES AND FORMS... Directive 3002.01E, Personnel Recovery in the Department of Defense. (o) Mortuary affairs. Contractor... Commander or as directed by the Secretary of Defense. (2) Contract performance in support of U.S. Armed...
Indirect plant defense against insect herbivores: a review.
Aljbory, Zainab; Chen, Ming-Shun
2018-02-01
Plants respond to herbivore attack by launching 2 types of defenses: direct defense and indirect defense. Direct defense includes all plant traits that increase the resistance of host plants to insect herbivores by affecting the physiology and/or behavior of the attackers. Indirect defense includes all traits that by themselves do not have significant direct impact on the attacking herbivores, but can attract natural enemies of the herbivores and thus reduce plant loss. When plants recognize herbivore-associated elicitors, they produce and release a blend of volatiles that can attract predators, parasites, and other natural enemies. Known herbivore-associated elicitors include fatty acid-amino acid conjugates, sulfur-containing fatty acids, fragments of cell walls, peptides, esters, and enzymes. Identified plant volatiles include terpenes, nitrogenous compounds, and indoles. In addition, constitive traits including extrafloral nectars, food bodies, and domatia can be further induced to higher levels and attract natural enemies as well as provide food and shelter to carnivores. A better understanding of indirect plant defense at global and componential levels via advanced high throughput technologies may lead to utilization of indirect defense in suppression of herbivore damage to plants. © 2016 Institute of Zoology, Chinese Academy of Sciences.
US Navy SHF SATCOM: Past, present and future
NASA Astrophysics Data System (ADS)
Bushnell, Christopher J.
1994-06-01
This thesis discusses the Navy's Super High Frequency Satellite Communications (SHF SATCOM) capabilities prior to Desert Shield/Desert Storm, and the requirements for future systems that were generated due to Navy SATCOM shortcomings during the Gulf War. The four-phased evolutionary approach the Navy has designed (based on post-war requirements) to provide itself with a medium for SHF SATCOM into the 21st Century, as well as the Defense Satellite Communications Systems (DSCS), are examined in detail. Decreasing defense budgets have begun to have a significant impact on future military satellite communication (MILSATCOM) systems. A cost comparison between utilization of DSCS III satellites and the INMARSAT commercial SATCOM system is presented. Recommended improvements to current MILSATCOM procedures and training practices are proposed that could improve operational C4I capabilities. Finally, this study determines that future SATCOM architectures should include a mixture of commercial systems and MILSATCOM systems to provide both cost savings and command and control protection.
32 CFR 323.6 - Exemption rules.
Code of Federal Regulations, 2013 CFR
2013-07-01
... DEFENSE LOGISTICS AGENCY PRIVACY PROGRAM § 323.6 Exemption rules. (a) The Director, DLA or designee may... proceedings. (c) Exempt Records Systems. All systems of records maintained by the Defense Logistics Agency... Identifier: S500.20 (Specific exemption). (1) System name: Defense Logistics Agency (DLA) Criminal Incident...
32 CFR 323.6 - Exemption rules.
Code of Federal Regulations, 2014 CFR
2014-07-01
... DEFENSE LOGISTICS AGENCY PRIVACY PROGRAM § 323.6 Exemption rules. (a) The Director, DLA or designee may... proceedings. (c) Exempt Records Systems. All systems of records maintained by the Defense Logistics Agency... Identifier: S500.20 (Specific exemption). (1) System name: Defense Logistics Agency (DLA) Criminal Incident...
Global Positioning System: Observations on Quarterly Reports from the Air Force
2016-10-17
Positioning System : Observations on Quarterly Reports from the Air Force The satellite-based Global Positioning System (GPS) provides positioning, navigation...infrastructure, and transportation safety. The Department of Defense (DOD)—specifically, the Air Force—develops and operates the GPS system , which...programs, including the most recent detailed assessment of the next generation operational control system (OCX) and development of military GPS
Transmission monitoring and control of strategic communication systems
NASA Astrophysics Data System (ADS)
Farrow, J. E.; Skerjanec, R. E.
1986-03-01
This paper discusses a minicomputer-based communication system monitor used by the U.S. Department of Defense to improve the service availability and reduce the operating costs of the new multichannel digital transmission systems. A brief history of the development of the monitor and a general description of the present-generation hardware and software are included.
Seven Defense Priorities for the New Administration
2016-12-01
building consume human and financial military resources for decades. New weapons like cyber and autonomous systems are aimed at the heart of the U.S...information infrastructure enables for adversaries and for the U.S.; 5. Anticipating intelligent systems and autonomy including numbers and...challenging in a complex electromagnetic environment ...............................................37 Space and the global positioning system play a
1990-04-01
SURVEILLANCE & WARNING SYTEMS A2C COMMAND & CONTROL ACTIVITIES A2D SPACE ACTIVITIES (STRATEGIC CONTROL & SURV) A2E STRAT CONTROL & SURV: COMMUNICATIONS A2F...STRATEGIC AIR DEFENSE 0501802A NIKE-AJAX (ARNS) (H) AID STRATEGIC AIR DEFENSE AIC SPACE DEFENSE OI02115N F-6 Squadrons (H) AIC SPACE DEFENSE 0102215N ABM ...WARNING SYTEMS 0102310F NCHC - TW/AA Systems A2B SURVEILLANCE & WARNIIIG SYTEMS 0102311F NCMC - Space Defense Systems A21 SURVEILLANCE & WARNING SYTEMS
Using a Red Team to devise countermeasures
NASA Astrophysics Data System (ADS)
Swedenburg, R. L.
1995-01-01
The ability of a defense system to operate effectively when deployed in battle is dependent on designs able to deal with countermeasures against the defense. The formation of a technical Red Team to stress the preliminary designs of the defensive system with technologically feasible and effective potential countermeasures provides a means to identify such potential countermeasures. This paper describes the experience of the U.S. Ballistic Missile Defense Organization's (BMDO) Theater Missile Defense Red Team since the Gulf War in 1991, the Red-Blue Exchange process, and the value it has provided to the designers of the U.S. Theater Missile Defense systems for developing robust systems. A wide-range of technologically feasible countermeasures has been devised, analyzed, tested for feasibility, and provided to the system developers for mitigation design. The process for independently analyzing possible susceptibilities of preliminary designs and exploiting the susceptibilities to identify possible countermeasures is explained. Designing and characterizing the Red Team's countermeasures, determining their feasibility, and analyzing their potential effectiveness against the defense are explained. A technique for the Blue Team's designers to deal with a wide range of potential countermeasures is explained.
Utilizing an Intelligent Tutoring System in Tactical Action Officer Sandbox
2014-06-01
Office of Naval Research Future Naval Capabilities, the Defense Technology Area Plan from 2005 and the Department of Defense Science and Technology ...LEFT BLANK v ABSTRACT The Office of Naval Research Future Naval Capabilities, the Defense Technology Area Plan from 2005 and the Department...of Defense Science and Technology Priorities for FY13-17 all share a focus on systems to promote warfighter performance. The goal of these systems is
Llandres, Ana L; Almohamad, Raki; Brévault, Thierry; Renou, Alain; Téréta, Idrissa; Jean, Janine; Goebel, François-Regis
2018-04-17
Enhancing cotton pest management using plant natural defenses has been described as a promising way to improve the management of crop pests. We here reviewed different studies on cotton growing systems to illustrate how an ancient technique called plant training, which includes plant topping and pruning, may contribute to this goal. Based on examples from cotton crops, we show how trained plants could be promoted to a state of enhanced defense that causes faster and more robust activation of their defense responses. We revisit agricultural benefits associated to this technique in cotton crops, with a focus on its potential as a supplementary tool for Integrated Pest Management (IPM). Particularly, we examine its role in mediating plant interactions with conspecific neighboring plants, pests and associated natural enemies. We propose a new IPM tool, plant training for induced defense, which involves inducing plant defense by artificial injuries. Experimental evidence from various studies shows that cotton training is a promising technique, particularly for smallholders, which can be used as part of an IPM program to significantly reduce insecticide use and to improve productivity in cotton farming. This article is protected by copyright. All rights reserved.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 32 National Defense 1 2013-07-01 2013-07-01 false Policy. 162.4 Section 162.4 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE DEFENSE CONTRACTING PRODUCTIVITY ENHANCING CAPITAL...D Component investment planning and of the Defense Planning, Programming, and Budgeting System (PPBS...
Code of Federal Regulations, 2010 CFR
2010-07-01
... 32 National Defense 1 2010-07-01 2010-07-01 false Policy. 162.4 Section 162.4 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE DEFENSE CONTRACTING PRODUCTIVITY ENHANCING CAPITAL...D Component investment planning and of the Defense Planning, Programming, and Budgeting System (PPBS...
Code of Federal Regulations, 2011 CFR
2011-07-01
... 32 National Defense 1 2011-07-01 2011-07-01 false Policy. 162.4 Section 162.4 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE DEFENSE CONTRACTING PRODUCTIVITY ENHANCING CAPITAL...D Component investment planning and of the Defense Planning, Programming, and Budgeting System (PPBS...
Code of Federal Regulations, 2012 CFR
2012-07-01
... 32 National Defense 1 2012-07-01 2012-07-01 false Policy. 162.4 Section 162.4 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE DEFENSE CONTRACTING PRODUCTIVITY ENHANCING CAPITAL...D Component investment planning and of the Defense Planning, Programming, and Budgeting System (PPBS...
Cost of space-based laser ballistic missile defense.
Field, G; Spergel, D
1986-03-21
Orbiting platforms carrying infrared lasers have been proposed as weapons forming the first tier of a ballistic missile defense system under the President's Strategic Defense Initiative. As each laser platform can destroy a limited number of missiles, one of several methods of countering such a system is to increase the number of offensive missiles. Hence it is important to know whether the cost-exchange ratio, defined as the ratio of the cost to the defense of destroying a missile to the cost to the offense of deploying an additional missile, is greater or less than 1. Although the technology to be used in a ballistic missile defense system is still extremely uncertain, it is useful to examine methods for calculating the cost-exchange ratio. As an example, the cost of an orbiting infrared laser ballistic missile defense system employed against intercontinental ballistic missiles launched simultaneously from a small area is compared to the cost of additional offensive missiles. If one adopts lower limits to the costs for the defense and upper limits to the costs for the offense, the cost-exchange ratio comes out substantially greater than 1. If these estimates are confirmed, such a ballistic missile defense system would be unable to maintain its effectiveness at less cost than it would take to proliferate the ballistic missiles necessary to overcome it and would therefore not satisfy the President's requirements for an effective strategic defense. Although the method is illustrated by applying it to a space-based infrared laser system, it should be straightforward to apply it to other proposed systems.
Cost of space-based laser ballistic missile defense
DOE Office of Scientific and Technical Information (OSTI.GOV)
Field, G.; Spergel, D.
1986-03-21
Orbiting platforms carrying infrared lasers have been proposed as weapons forming the first tier of a ballistic missile defense system under the President's Strategic Defense Initiative. As each laser platform can destroy a limited number of missiles, one of several methods of countering such a system is to increase the number of offensive missiles. Hence it is important to know whether the cost-exchange ratio, defined as the ratio of the cost to the defense of destroying a missile to the cost to the offense of deploying an additional missile, is greater or less than 1. Although the technology to bemore » used in a ballistic missile defense system is still extremely uncertain, it is useful to examine methods for calculating the cost-exchange ration. As an example, the cost of an orbiting infrared laser ballistic missile defense system employed against intercontinental ballistic missiles launched simultaneously from a small area is compared to the cost of additional offensive missiles. If one adopts lower limits to the costs for the defense and upper limits to the costs for the offense, the cost-exchange ratio comes out substantially greater than 1. If these estimates are confirmed, such a ballistic missile defense system would be unable to maintain its effectiveness at less cost than it would take to proliferate the ballistic missiles necessary to overcome it and would therefore not satisfy the President's requirements for an effective strategic defense. Although the method is illustrated by applying it to a space-based infrared laser system, it should be straightforward to apply it to other proposed systems. 28 references, 2 tables.« less
Federal Register 2010, 2011, 2012, 2013, 2014
2010-09-08
... Procurement of Major Systems of the Department of Defense.'' DATES: Effective Date: September 8, 2010. FOR... 217 Government procurement. Ynette R. Shelkin, Editor, Defense Acquisition Regulations System. 0... funding or reprogramming for procurement of a major system under a multiyear contract authorized under...
Weil, Robert; Laplantine, Emmanuel; Génin, Pierre
2016-06-01
The innate immune system has evolved to detect and neutralize viral invasions. Triggering of this defense mechanism relies on the production and secretion of soluble factors that stimulate intracellular antiviral defense mechanisms. The Tank Binding Kinase 1 (TBK1) is a serine/threonine kinase in the innate immune signaling pathways including the antiviral response and the host defense against cytosolic infection by bacteries. Given the critical roles of TBK1, important regulatory mechanisms are required to regulate its activity. Among these, Optineurin (Optn) was shown to negatively regulate the interferon response, in addition to its important role in membrane trafficking, protein secretion, autophagy and cell division. As Optn does not carry any enzymatic activity, its functions depend on its precise subcellular localization and its interaction with other proteins, especially with components of the innate immune pathway. This review highlights advances in our understanding of Optn mechanisms of action with focus on the relationships between Optn and TBK1 and their implication in host defense against pathogens. Specifically, how the antiviral immune system is controlled during the cell cycle by the Optn/TBK1 axis and the physiological consequences of this regulatory mechanism are described. This review may serve to a better understanding of the relationships between the different functions of Optn, including those related to immune responses and its associated pathologies such as primary open-angle glaucoma, amyotrophic lateral sclerosis and Paget's disease of bone. Copyright © 2016 Elsevier Ltd. All rights reserved.
Federal Register 2010, 2011, 2012, 2013, 2014
2012-02-24
...The Food and Drug Administration (FDA) is announcing an opportunity for public comment on the proposed collection of certain information by the Agency. Under the Paperwork Reduction Act of 1995 (the PRA), Federal Agencies are required to publish notice in the Federal Register concerning each proposed collection of information and to allow 60 days for public comment in response to the notice. This notice solicits comments on a survey entitled ``Improving Food Safety and Defense Capacity of the State and Local Level: Review of State and Local Capacities.'' The data collection will obtain knowledge of State and local capacities including food safety defense staffing and expertise, laboratory capacities, and information systems to support food and feed safety and defense.
Technical Basis for Evaluating Software-Related Common-Cause Failures
DOE Office of Scientific and Technical Information (OSTI.GOV)
Muhlheim, Michael David; Wood, Richard
2016-04-01
The instrumentation and control (I&C) system architecture at a nuclear power plant (NPP) incorporates protections against common-cause failures (CCFs) through the use of diversity and defense-in-depth. Even for well-established analog-based I&C system designs, the potential for CCFs of multiple systems (or redundancies within a system) constitutes a credible threat to defeating the defense-in-depth provisions within the I&C system architectures. The integration of digital technologies into the I&C systems provides many advantages compared to the aging analog systems with respect to reliability, maintenance, operability, and cost effectiveness. However, maintaining the diversity and defense-in-depth for both the hardware and software within themore » digital system is challenging. In fact, the introduction of digital technologies may actually increase the potential for CCF vulnerabilities because of the introduction of undetected systematic faults. These systematic faults are defined as a “design fault located in a software component” and at a high level, are predominately the result of (1) errors in the requirement specification, (2) inadequate provisions to account for design limits (e.g., environmental stress), or (3) technical faults incorporated in the internal system (or architectural) design or implementation. Other technology-neutral CCF concerns include hardware design errors, equipment qualification deficiencies, installation or maintenance errors, instrument loop scaling and setpoint mistakes.« less
U.S. Outpatient Beneficiary Satisfaction at Korean Hospitals
2008-05-12
aligned with the Department of Defense’s Army Provider Level Satisfaction Survey. The survey utilizes a Likert 5-point scale system . The setting included...outpatient care to Samsung , Dongsan, and Dankook hospitals, from September-November 2007. The analysis measured overall patient satisfaction as it...Satisfaction Survey (APLSS). The survey utilizes a Likert 5-point scale system . The setting included medical facilities within the ROK that participate under a
Plant Responses to Pathogen Attack: Small RNAs in Focus.
Islam, Waqar; Noman, Ali; Qasim, Muhammad; Wang, Liande
2018-02-08
Small RNAs (sRNA) are a significant group of gene expression regulators for multiple biological processes in eukaryotes. In plants, many sRNA silencing pathways produce extensive array of sRNAs with specialized roles. The evidence on record advocates for the functions of sRNAs during plant microbe interactions. Host sRNAs are reckoned as mandatory elements of plant defense. sRNAs involved in plant defense processes via different pathways include both short interfering RNA (siRNA) and microRNA (miRNA) that actively regulate immunity in response to pathogenic attack via tackling pathogen-associated molecular patterns (PAMPs) and other effectors. In response to pathogen attack, plants protect themselves with the help of sRNA-dependent immune systems. That sRNA-mediated plant defense responses play a role during infections is an established fact. However, the regulations of several sRNAs still need extensive research. In this review, we discussed the topical advancements and findings relevant to pathogen attack and plant defense mediated by sRNAs. We attempted to point out diverse sRNAs as key defenders in plant systems. It is hoped that sRNAs would be exploited as a mainstream player to achieve food security by tackling different plant diseases.
Plant Responses to Pathogen Attack: Small RNAs in Focus
2018-01-01
Small RNAs (sRNA) are a significant group of gene expression regulators for multiple biological processes in eukaryotes. In plants, many sRNA silencing pathways produce extensive array of sRNAs with specialized roles. The evidence on record advocates for the functions of sRNAs during plant microbe interactions. Host sRNAs are reckoned as mandatory elements of plant defense. sRNAs involved in plant defense processes via different pathways include both short interfering RNA (siRNA) and microRNA (miRNA) that actively regulate immunity in response to pathogenic attack via tackling pathogen-associated molecular patterns (PAMPs) and other effectors. In response to pathogen attack, plants protect themselves with the help of sRNA-dependent immune systems. That sRNA-mediated plant defense responses play a role during infections is an established fact. However, the regulations of several sRNAs still need extensive research. In this review, we discussed the topical advancements and findings relevant to pathogen attack and plant defense mediated by sRNAs. We attempted to point out diverse sRNAs as key defenders in plant systems. It is hoped that sRNAs would be exploited as a mainstream player to achieve food security by tackling different plant diseases. PMID:29419801
5 CFR 9901.221 - Classification requirements.
Code of Federal Regulations, 2011 CFR
2011-01-01
... Section 9901.221 Administrative Personnel DEPARTMENT OF DEFENSE HUMAN RESOURCES MANAGEMENT AND LABOR RELATIONS SYSTEMS (DEPARTMENT OF DEFENSE-OFFICE OF PERSONNEL MANAGEMENT) DEPARTMENT OF DEFENSE NATIONAL SECURITY PERSONNEL SYSTEM (NSPS) Classification Classification Process § 9901.221 Classification...
Code of Federal Regulations, 2011 CFR
2011-10-01
... 242.7301 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CONTRACT MANAGEMENT CONTRACT ADMINISTRATION AND AUDIT SERVICES Contractor Insurance/Pension Review.../Insurance Pension Review (CIPR). Defense Contract Management Agency (DCMA) insurance/pension specialists and...
Code of Federal Regulations, 2010 CFR
2010-10-01
... 242.7301 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CONTRACT MANAGEMENT CONTRACT ADMINISTRATION AND AUDIT SERVICES Contractor Insurance/Pension Review.../Insurance Pension Review (CIPR). Defense Contract Management Agency (DCMA) insurance/pension specialists and...
DOE Office of Scientific and Technical Information (OSTI.GOV)
Not Available
1992-06-26
Since 1941, the 1,100-acre Ogden Defense Depot (DDOU) site, located in Ogden, Weber County, Utah, has been a key installation in the Department of Defense supply system. Operable Unit 1, which is located in the southwest part of the DDOU, is composed of the backfill material in the Plain City Canal, Burial Site 1, and Burial Site 3-B. Burial Site 1 was reported to have been used for the disposal of riot control agent (chloroacetophenone) and white smoke (hexachloroethane) containers in the 1940's. In the early 1960's, Burial Site 3-B was reportedly the burying ground for over 1,000 arctic-style rubbermore » boots. The ROD addresses a final remedy for OU1 that will reduce the principal threats posed by contaminated soil and shallow ground water at the site. The primary contaminants of concern affecting the soil, debris, and ground water are VOCs, including TCE; other organics, including dioxins and pesticides; and metals, including arsenic and lead.« less
75 FR 10471 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2010-03-08
... DEPARTMENT OF DEFENSE Office of the Secretary [Docket ID DOD-2010-OS-0023] Privacy Act of 1974; System of Records AGENCY: Defense Logistics Agency, DoD. ACTION: Notice to amend a system of records..., 2010. Mitchell S. Bryman, Alternate OSD Federal Register Liaison Officer, Department of Defense. S650...
75 FR 3178 - Defense Federal Acquisition Regulation Supplement; Lead System Integrators
Federal Register 2010, 2011, 2012, 2013, 2014
2010-01-20
... Government procurement. Amy G. Williams, Editor, Defense Acquisition Regulations System. 0 Accordingly, the..., without change, an interim rule amending the Defense Federal Acquisition Regulation Supplement (DFARS) to... limitations on the award of new contracts for lead system integrator functions in the acquisition of major DoD...
32 CFR Appendix H to Part 323 - DLA Exemption Rules
Code of Federal Regulations, 2012 CFR
2012-07-01
... PROGRAM DEFENSE LOGISTICS AGENCY PRIVACY PROGRAM Pt. 323, App. H Appendix H to Part 323—DLA Exemption Rules Exempted Records Systems. All systems of records maintained by the Defense Logistics Agency will.... b. ID: S500.20 (Specific exemption). 1. System name: Defense Logistics Agency Criminal Incident...
32 CFR Appendix A to Part 77 - DD Form 2580, Operation Transition Department of Defense
Code of Federal Regulations, 2011 CFR
2011-07-01
... 32 National Defense 1 2011-07-01 2011-07-01 false DD Form 2580, Operation Transition Department of Defense A Appendix A to Part 77 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE... to Part 77—DD Form 2580, Operation Transition Department of Defense Outplacement and Referral System...
32 CFR Appendix A to Part 77 - DD Form 2580, Operation Transition Department of Defense
Code of Federal Regulations, 2010 CFR
2010-07-01
... 32 National Defense 1 2010-07-01 2010-07-01 false DD Form 2580, Operation Transition Department of Defense A Appendix A to Part 77 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE... to Part 77—DD Form 2580, Operation Transition Department of Defense Outplacement and Referral System...
32 CFR Appendix A to Part 77 - DD Form 2580, Operation Transition Department of Defense
Code of Federal Regulations, 2012 CFR
2012-07-01
... 32 National Defense 1 2012-07-01 2012-07-01 false DD Form 2580, Operation Transition Department of Defense A Appendix A to Part 77 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE... to Part 77—DD Form 2580, Operation Transition Department of Defense Outplacement and Referral System...
32 CFR Appendix A to Part 77 - DD Form 2580, Operation Transition Department of Defense
Code of Federal Regulations, 2013 CFR
2013-07-01
... 32 National Defense 1 2013-07-01 2013-07-01 false DD Form 2580, Operation Transition Department of Defense A Appendix A to Part 77 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE... to Part 77—DD Form 2580, Operation Transition Department of Defense Outplacement and Referral System...
32 CFR Appendix A to Part 77 - DD Form 2580, Operation Transition Department of Defense
Code of Federal Regulations, 2014 CFR
2014-07-01
... 32 National Defense 1 2014-07-01 2014-07-01 false DD Form 2580, Operation Transition Department of Defense A Appendix A to Part 77 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE... to Part 77—DD Form 2580, Operation Transition Department of Defense Outplacement and Referral System...
Federal Register 2010, 2011, 2012, 2013, 2014
2010-06-08
... elements of the Department of Homeland Security concerned with the analysis of intelligence information... DEPARTMENT OF DEFENSE Defense Acquisition Regulations System 48 CFR Part 217 RIN 0750-AG67 Defense Federal Acquisition Regulation Supplement; Limitations on Procurements With Non-Defense Agencies (DFARS...
32 CFR 37.875 - Should my TIA include a provision concerning foreign access to technology?
Code of Federal Regulations, 2013 CFR
2013-07-01
... 32 National Defense 1 2013-07-01 2013-07-01 false Should my TIA include a provision concerning foreign access to technology? 37.875 Section 37.875 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE DoD GRANT AND AGREEMENT REGULATIONS TECHNOLOGY INVESTMENT AGREEMENTS Award Terms...
32 CFR 37.875 - Should my TIA include a provision concerning foreign access to technology?
Code of Federal Regulations, 2010 CFR
2010-07-01
... 32 National Defense 1 2010-07-01 2010-07-01 false Should my TIA include a provision concerning foreign access to technology? 37.875 Section 37.875 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE DoD GRANT AND AGREEMENT REGULATIONS TECHNOLOGY INVESTMENT AGREEMENTS Award Terms...
32 CFR 37.875 - Should my TIA include a provision concerning foreign access to technology?
Code of Federal Regulations, 2012 CFR
2012-07-01
... 32 National Defense 1 2012-07-01 2012-07-01 false Should my TIA include a provision concerning foreign access to technology? 37.875 Section 37.875 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE DoD GRANT AND AGREEMENT REGULATIONS TECHNOLOGY INVESTMENT AGREEMENTS Award Terms...
32 CFR 37.875 - Should my TIA include a provision concerning foreign access to technology?
Code of Federal Regulations, 2014 CFR
2014-07-01
... 32 National Defense 1 2014-07-01 2014-07-01 false Should my TIA include a provision concerning foreign access to technology? 37.875 Section 37.875 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE DoD GRANT AND AGREEMENT REGULATIONS TECHNOLOGY INVESTMENT AGREEMENTS Award Terms...
32 CFR 37.875 - Should my TIA include a provision concerning foreign access to technology?
Code of Federal Regulations, 2011 CFR
2011-07-01
... 32 National Defense 1 2011-07-01 2011-07-01 false Should my TIA include a provision concerning foreign access to technology? 37.875 Section 37.875 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE DoD GRANT AND AGREEMENT REGULATIONS TECHNOLOGY INVESTMENT AGREEMENTS Award Terms...
Code of Federal Regulations, 2013 CFR
2013-07-01
... 32 National Defense 1 2013-07-01 2013-07-01 false What requirements must I include for periodic reports on program and business status? 37.880 Section 37.880 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE DoD GRANT AND AGREEMENT REGULATIONS TECHNOLOGY INVESTMENT AGREEMENTS...
Code of Federal Regulations, 2010 CFR
2010-07-01
... 32 National Defense 1 2010-07-01 2010-07-01 false What requirements must I include for periodic reports on program and business status? 37.880 Section 37.880 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE DoD GRANT AND AGREEMENT REGULATIONS TECHNOLOGY INVESTMENT AGREEMENTS...
Code of Federal Regulations, 2014 CFR
2014-07-01
... 32 National Defense 1 2014-07-01 2014-07-01 false What requirements must I include for periodic reports on program and business status? 37.880 Section 37.880 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE DoD GRANT AND AGREEMENT REGULATIONS TECHNOLOGY INVESTMENT AGREEMENTS...
Code of Federal Regulations, 2012 CFR
2012-07-01
... 32 National Defense 1 2012-07-01 2012-07-01 false What requirements must I include for periodic reports on program and business status? 37.880 Section 37.880 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE DoD GRANT AND AGREEMENT REGULATIONS TECHNOLOGY INVESTMENT AGREEMENTS...
Code of Federal Regulations, 2011 CFR
2011-07-01
... 32 National Defense 1 2011-07-01 2011-07-01 false What requirements must I include for periodic reports on program and business status? 37.880 Section 37.880 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE DoD GRANT AND AGREEMENT REGULATIONS TECHNOLOGY INVESTMENT AGREEMENTS...
Gahm, Gregory A; Reger, Mark A; Kinn, Julie T; Luxton, David D; Skopp, Nancy A; Bush, Nigel E
2012-03-01
The US National Strategy for Suicide Prevention (National Strategy) described 11 goals across multiple areas, including suicide surveillance. Consistent with these goals, the Department of Defense (DoD) has engaged aggressively in the area of suicide surveillance. The DoD's population-based surveillance system, the DoD Suicide Event Report (DoDSER) collects information on suicides and suicide attempts for all branches of the military. Data collected includes suicide event details, treatment history, military and psychosocial history, and psychosocial stressors at the time of the event. Lessons learned from the DoDSER program are shared to assist other public health professionals working to address the National Strategy objectives.
48 CFR 225.7016-1 - Definitions.
Code of Federal Regulations, 2010 CFR
2010-10-01
... with Foreign Entities for the Conduct of Ballistic Missile Defense Research, Development, Test, and... Section 225.7016-1 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE SOCIOECONOMIC PROGRAMS FOREIGN ACQUISITION Authorization Acts, Appropriations Acts, and...
48 CFR 216.504 - Indefinite-quantity contracts.
Code of Federal Regulations, 2010 CFR
2010-10-01
... Deputy Director, Defense Procurement and Acquisition Policy (Contract Policy and International... contracts. 216.504 Section 216.504 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CONTRACTING METHODS AND CONTRACT TYPES TYPES OF CONTRACTS Indefinite...
5 CFR 9901.104 - Scope of authority.
Code of Federal Regulations, 2010 CFR
2010-01-01
....104 Administrative Personnel DEPARTMENT OF DEFENSE HUMAN RESOURCES MANAGEMENT AND LABOR RELATIONS SYSTEMS (DEPARTMENT OF DEFENSE-OFFICE OF PERSONNEL MANAGEMENT) DEPARTMENT OF DEFENSE NATIONAL SECURITY... with performance appraisal systems; (b) Chapter 51, dealing with General Schedule job classification...
Code of Federal Regulations, 2010 CFR
2010-01-01
... Administrative Personnel DEPARTMENT OF DEFENSE HUMAN RESOURCES MANAGEMENT AND LABOR RELATIONS SYSTEMS (DEPARTMENT OF DEFENSE-OFFICE OF PERSONNEL MANAGEMENT) DEPARTMENT OF DEFENSE NATIONAL SECURITY PERSONNEL SYSTEM (NSPS) Staffing and Employment General § 9901.504 Definitions. In this subpart— Career conditional...
DOE Office of Scientific and Technical Information (OSTI.GOV)
Dwight, Carla
The Department of Energy's Space and Defense Power Systems program provides a unique capability for supplying power systems that function in remote or hostile environments. This capability has been functioning since the early 1960s and counts the National Aeronautics and Space Administration as one of its most prominent customers. This enabling technology has assisted the exploration of our solar system including the planets Jupiter, Saturn, Mars, Neptune, and soon Pluto. This capability is one-of-kind in the world in terms of its experience (over five decades), breadth of power systems flown (over two dozen to date) and range of power levelsmore » (watts to hundreds of watts). This document describes the various components of that infrastructure, work scope, funding needs, and its strategic plans going forward.« less
48 CFR 3002.101 - Definitions.
Code of Federal Regulations, 2014 CFR
2014-10-01
... national defense, homeland security or foreign policy. This definition includes the following categories of... Section 3002.101 Federal Acquisition Regulations System DEPARTMENT OF HOMELAND SECURITY, HOMELAND SECURITY... functions assigned by the Federal Acquisition Regulation and the Homeland Security Acquisition Regulation...
48 CFR 3002.101 - Definitions.
Code of Federal Regulations, 2013 CFR
2013-10-01
... national defense, homeland security or foreign policy. This definition includes the following categories of... Section 3002.101 Federal Acquisition Regulations System DEPARTMENT OF HOMELAND SECURITY, HOMELAND SECURITY... functions assigned by the Federal Acquisition Regulation and the Homeland Security Acquisition Regulation...
48 CFR 3002.101 - Definitions.
Code of Federal Regulations, 2012 CFR
2012-10-01
... national defense, homeland security or foreign policy. This definition includes the following categories of... Section 3002.101 Federal Acquisition Regulations System DEPARTMENT OF HOMELAND SECURITY, HOMELAND SECURITY... functions assigned by the Federal Acquisition Regulation and the Homeland Security Acquisition Regulation...
Phase 1 Development Report for the SESSA Toolkit.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Knowlton, Robert G.; Melton, Brad J; Anderson, Robert J.
The Site Exploitation System for Situational Awareness ( SESSA ) tool kit , developed by Sandia National Laboratories (SNL) , is a comprehensive de cision support system for crime scene data acquisition and Sensitive Site Exploitation (SSE). SESSA is an outgrowth of another SNL developed decision support system , the Building R estoration Operations Optimization Model (BROOM), a hardware/software solution for data acquisition, data management, and data analysis. SESSA was designed to meet forensic crime scene needs as defined by the DoD's Military Criminal Investigation Organiza tion (MCIO) . SESSA is a very comprehensive toolki t with a considerable amountmore » of database information managed through a Microsoft SQL (Structured Query Language) database engine, a Geographical Information System (GIS) engine that provides comprehensive m apping capabilities, as well as a an intuitive Graphical User Interface (GUI) . An electronic sketch pad module is included. The system also has the ability to efficiently generate necessary forms for forensic crime scene investigations (e.g., evidence submittal, laboratory requests, and scene notes). SESSA allows the user to capture photos on site, and can read and generate ba rcode labels that limit transcription errors. SESSA runs on PC computers running Windows 7, but is optimized for touch - screen tablet computers running Windows for ease of use at crime scenes and on SSE deployments. A prototype system for 3 - dimensional (3 D) mapping and measur e ments was also developed to complement the SESSA software. The mapping system employs a visual/ depth sensor that captures data to create 3D visualizations of an interior space and to make distance measurements with centimeter - level a ccuracy. Output of this 3D Model Builder module provides a virtual 3D %22walk - through%22 of a crime scene. The 3D mapping system is much less expensive and easier to use than competitive systems. This document covers the basic installation and operation of th e SESSA tool kit in order to give the user enough information to start using the tool kit . SESSA is currently a prototype system and this documentation covers the initial release of the tool kit . Funding for SESSA was provided by the Department of Defense (D oD), Assistant Secretary of Defense for Research and Engineering (ASD(R&E)) Rapid Fielding (RF) organization. The project was managed by the Defense Forensic Science Center (DFSC) , formerly known as the U.S. Army Criminal Investigation Laboratory (USACIL) . ACKNOWLEDGEMENTS The authors wish to acknowledge the funding support for the development of the Site Exploitation System for Situational Awareness (SESSA) toolkit from the Department of Defense (DoD), Assistant Secretary of Defense for Research and Engineering (ASD(R&E)) Rapid Fielding (RF) organization. The project was managed by the Defense Forensic Science Center (DFSC) , formerly known as the U.S. Army Criminal Investigation Laboratory (USACIL). Special thanks to Mr. Garold Warner, of DFSC, who served as the Project Manager. Individuals that worked on the design, functional attributes, algorithm development, system arc hitecture, and software programming include: Robert Knowlton, Brad Melton, Robert Anderson, and Wendy Amai.« less
Epstein, Nancy E
2010-04-07
To determine whether patients who become quadriplegic following cervical spine surgery are adequately compensated by our present medico-legal system. The outcomes of malpractice suits obtained from Verdict Search (East Islip, NY, USA), a medico-legal journal, were evaluated over a 20-year period. Although the present malpractice system generously rewards many quadriplegic patients with substantial settlements/ Plaintiffs' verdicts, a subset receive lesser reimbursements (verdicts/settlements], while others with defense verdicts receive no compensatory damages. Utilizing Verdict Search, 54 cases involving quadriplegia following cervical spine surgery were reviewed for a 20-year interval (1988-2008). The reason(s) for the suit, the defendants, the legal outcome, and the time to outcome were identified. Operations included 25 anterior cervical procedures, 22 posterior cervical operations, 1 circumferential cervical procedure, and 6 cases in which the cervical operations were not defined. The four most prominent legal allegations for suits included negligent surgery (47 cases), lack of informed consent (23 cases), failure to diagnose/treat (33 cases), and failure to brace (15 cases). Forty-four of the 54 suits included spine surgeons. There were 19 Plaintiffs' verdicts (average US $5.9 million, range US $540,000-US $18.4 million), and 20 settlements (average US $2.8 million, range US $66,500-US $12.0 million). Fifteen quadriplegic patients with defense verdicts received no compensatory damages. The average time to verdicts/settlements was 4.3 years. For 54 patients who were quadriplegic following cervical spine surgery, 15 (28%) with defense verdicts received no compensatory damages. Under a No-Fault system, quadriplegic patients would qualify for a "reasonable" level of compensation over a "shorter" time frame.
Uncertainties in building a strategic defense.
Zraket, C A
1987-03-27
Building a strategic defense against nuclear ballistic missiles involves complex and uncertain functional, spatial, and temporal relations. Such a defensive system would evolve and grow over decades. It is too complex, dynamic, and interactive to be fully understood initially by design, analysis, and experiments. Uncertainties exist in the formulation of requirements and in the research and design of a defense architecture that can be implemented incrementally and be fully tested to operate reliably. The analysis and measurement of system survivability, performance, and cost-effectiveness are critical to this process. Similar complexities exist for an adversary's system that would suppress or use countermeasures against a missile defense. Problems and opportunities posed by these relations are described, with emphasis on the unique characteristics and vulnerabilities of space-based systems.
Joint Operational Medicine Information Systems (JOMIS)
2016-03-01
Component is Program Executive Office (PEO) Department of Defense (DoD) Healthcare Management Systems (DHMS) for Defense Health Agency (DHA). Responsible...AT&L)) and the Program Executive Office (PEO) Defense Healthcare Management Systems (DHMS). Operational medicine is the application of routine and...acquired by the DoD Healthcare Management System Modernization (DHMSM) program for Health Care Delivery (HCD) capabilities. JOMIS future release(s
2010-03-01
CODIFYING INFORMATION ASSURANCE CONTROLS FOR DEPARTMENT OF DEFENSE (DOD) SUPERVISORY CONTROL AND DATA...Force, Department of Defense, or the U.S. Government. AFIT/GCO/ENG/10-13 CODIFYING INFORMATION ASSURANCE CONTROLS FOR DEPARTMENT OF...DEFENSE (DOD) SUPERVISORY CONTROL AND DATA ACQUISITION (SCADA) SYSTEMS THESIS Presented to the Faculty Department of Electrical and Computer
Wellman, Aaron D; Coad, Sam C; Goulet, Grant C; McLellan, Christopher P
2016-01-01
The aim of the present study was to examine the competitive physiological movement demands of National Collegiate Athletic Association (NCAA) Division I college football players using portable global positioning system (GPS) technology during games and to examine positional groups within offensive and defensive teams, to determine if a player's physiological requirements during games are influenced by playing position. Thirty-three NCAA Division I Football Bowl Subdivision football players were monitored using GPS receivers with integrated accelerometers (GPSports) during 12 regular season games throughout the 2014 season. Individual data sets (n = 295) from players were divided into offensive and defensive teams and subsequent position groups. Movement profile characteristics, including total, low-intensity, moderate-intensity, high-intensity, and sprint running distances (m), sprint counts, and acceleration and deceleration efforts, were assessed during games. A one-way ANOVA and post-hoc Bonferroni statistical analysis were used to determine differences in movement profiles between each position group within offensive and defensive teams. For both offensive and defensive teams, significant (p ≤ 0.05) differences exist between positional groups for game physical performance requirements. The results of the present study identified that wide receivers and defensive backs completed significantly (p ≤ 0.05) greater total distance, high-intensity running, sprint distance, and high-intensity acceleration and deceleration efforts than their respective offensive and defensive positional groups. Data from the present study provide novel quantification of position-specific physical demands of college football games and support the use of position-specific training in the preparation of NCAA Division I college football players for competition.
1990 Annual Tropical Cyclone Report
1995-01-01
land) - followed further loss of convective organization as system underwent increased vertical wind shear and loss of latent and sensible heat. III...FOLXTECHNICOF HONG KONG CIUDAD UNIVERSITARLA,M)XICO CML DEFENSE, BELAU CML DEFENSE, MAJURO CML DEFENSE, POHNPEI CML DEFENSE, SAIPAN CML DEFENSE, TRUK
75 FR 22569 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2010-04-29
... DEPARTMENT OF DEFENSE Department of the Air Force [Docket ID: USAF-2010-0014] Privacy Act of 1974... inventory of record systems subject to the Privacy Act of 1974, (5 U.S.C. 552a), as amended. DATES: This... Internet at http://www.regulations.gov as they are received without change, including any personal...
75 FR 33794 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2010-06-15
... DEPARTMENT OF DEFENSE Department of the Army [Docket ID: USA-2010-0013] Privacy Act of 1974... inventory of record systems subject to the Privacy Act of 1974, (5 U.S.C. 552a), as amended. DATES: This... on the Internet at http://www.regulations.gov as they are received without change, including any...
Acknowledging Disproportionate Outcomes and Changing Service Delivery
ERIC Educational Resources Information Center
McRoy, Ruth G.
2008-01-01
Child welfare is not the only system in which disparities have been identified in U.S. foster care. According to the recent Children's Defense Fund's report "America's Cradle to Prison Pipeline," racial and economic disparities exist in many systems including child welfare, health care, mental health, education, and juvenile and criminal justice.…
77 FR 31591 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2012-05-29
... DEPARTMENT OF DEFENSE Department of the Air Force [Docket ID USAF-2012-0011] Privacy Act of 1974... systems subject to the Privacy Act of 1974 (5 U.S.C. 552a), as amended. DATES: This proposed action will... Internet at http://www.regulations.gov as they are received without change, including any personal...
The United States Army 1996 Modernization Plan.
1996-03-08
and a cadre of operations, intelligence, fire support, air defense, and nuclear, biological, and chemical warfare personnel. As required, ARSPACE will...aerial and stand-off chemical and biological detection systems. " Decontamination improvements include Modular Decontamination System fielding in the near... Chemical . As many as 25 nations are producing and stockpiling chemical weapons. Weapons systems from mortars to missiles can deliver chemical warfare (CW
Toskala, Elina
2014-09-01
Knowledge of our immune system functions is critical for understanding allergic airway disease development as well as for selection of appropriate diagnostic and therapeutic options for patients with respiratory allergies. This review explains the current understanding of the basic immunology of the upper airways and the pathophysiology of allergic responses, including the mechanisms behind allergic rhinitis. The immune system can be divided to 2 main defense systems that function differently-innate immunity and adaptive immunity. Innate immunity includes several defensive mechanisms such as anatomic or physical barriers, physiological barriers, phagocytosis, and inflammation. The adaptive immune response is activated in an antigen-specific way to provide for the elimination of antigen and induce lasting protection. Hypersensitivity reactions occur when an exaggerated adaptive immune response is activated. Allergic rhinitis is an example of a type I, immunoglobulin E, mediated hypersensitivity reaction. Today we have several immunomodulatory treatment options for patients with allergic airway diseases, such as subcutaneous and sublingual immunotherapy. An understanding of the basics of our immune system and its method of functions is key for using these therapies appropriately. © 2014 ARS-AAOA, LLC.
Hitting the sweet spot-glycans as targets of fungal defense effector proteins.
Künzler, Markus
2015-05-06
Organisms which rely solely on innate defense systems must combat a large number of antagonists with a comparably low number of defense effector molecules. As one solution of this problem, these organisms have evolved effector molecules targeting epitopes that are conserved between different antagonists of a specific taxon or, if possible, even of different taxa. In order to restrict the activity of the defense effector molecules to physiologically relevant taxa, these target epitopes should, on the other hand, be taxon-specific and easily accessible. Glycans fulfill all these requirements and are therefore a preferred target of defense effector molecules, in particular defense proteins. Here, we review this defense strategy using the example of the defense system of multicellular (filamentous) fungi against microbial competitors and animal predators.
5 CFR 9901.222 - Review of classification decisions.
Code of Federal Regulations, 2011 CFR
2011-01-01
....222 Section 9901.222 Administrative Personnel DEPARTMENT OF DEFENSE HUMAN RESOURCES MANAGEMENT AND LABOR RELATIONS SYSTEMS (DEPARTMENT OF DEFENSE-OFFICE OF PERSONNEL MANAGEMENT) DEPARTMENT OF DEFENSE NATIONAL SECURITY PERSONNEL SYSTEM (NSPS) Classification Classification Process § 9901.222 Review of...
48 CFR 225.7016-2 - Restriction.
Code of Federal Regulations, 2010 CFR
2010-10-01
... the Ballistic Missile Defense Program. [68 FR 15627, Mar. 31, 2003. Redesignated at 74 FR 53413, Oct... Section 225.7016-2 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE SOCIOECONOMIC PROGRAMS FOREIGN ACQUISITION Authorization Acts, Appropriations Acts, and...
Code of Federal Regulations, 2011 CFR
2011-01-01
... Administrative Personnel DEPARTMENT OF DEFENSE HUMAN RESOURCES MANAGEMENT AND LABOR RELATIONS SYSTEMS (DEPARTMENT OF DEFENSE-OFFICE OF PERSONNEL MANAGEMENT) DEPARTMENT OF DEFENSE NATIONAL SECURITY PERSONNEL SYSTEM... accomplishment of the organization's mission and goals. CONUS or Continental United States means the States of...
Code of Federal Regulations, 2010 CFR
2010-01-01
... Administrative Personnel DEPARTMENT OF DEFENSE HUMAN RESOURCES MANAGEMENT AND LABOR RELATIONS SYSTEMS (DEPARTMENT OF DEFENSE-OFFICE OF PERSONNEL MANAGEMENT) DEPARTMENT OF DEFENSE NATIONAL SECURITY PERSONNEL SYSTEM... accomplishment of the organization's mission and goals. CONUS or Continental United States means the States of...
Code of Federal Regulations, 2010 CFR
2010-01-01
... Administrative Personnel DEPARTMENT OF DEFENSE HUMAN RESOURCES MANAGEMENT AND LABOR RELATIONS SYSTEMS (DEPARTMENT OF DEFENSE-OFFICE OF PERSONNEL MANAGEMENT) DEPARTMENT OF DEFENSE NATIONAL SECURITY PERSONNEL SYSTEM (NSPS) Performance Management § 9901.404 Definitions. In this subpart— Appraisal means the review and...
5 CFR 9901.413 - Reconsideration of ratings.
Code of Federal Regulations, 2010 CFR
2010-01-01
... Section 9901.413 Administrative Personnel DEPARTMENT OF DEFENSE HUMAN RESOURCES MANAGEMENT AND LABOR RELATIONS SYSTEMS (DEPARTMENT OF DEFENSE-OFFICE OF PERSONNEL MANAGEMENT) DEPARTMENT OF DEFENSE NATIONAL SECURITY PERSONNEL SYSTEM (NSPS) Performance Management § 9901.413 Reconsideration of ratings. (a...
Code of Federal Regulations, 2010 CFR
2010-07-01
...' financial, property, and purchasing systems? 37.605 Section 37.605 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE DoD GRANT AND AGREEMENT REGULATIONS TECHNOLOGY INVESTMENT AGREEMENTS Award Terms Affecting Participants' Financial, Property, and Purchasing Systems § 37.605 What is the...
76 FR 66916 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2011-10-28
... DEPARTMENT OF DEFENSE Office of the Secretary [Docket ID DOD-2011-OS-0118] Privacy Act of 1974; System of Records AGENCY: Office of the Secretary, Department of Defense (DoD). ACTION: Notice to Amend a.... Aaron Siegel, Alternate OSD Federal Register Liaison Officer, Department of Defense. DWHS E05 System...
76 FR 76959 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2011-12-09
... DEPARTMENT OF DEFENSE Office of the Secretary [Docket ID: DOD-2011-OS-0143] Privacy Act of 1974; System of Records AGENCY: Office of the Secretary, Department of Defense (DoD). ACTION: Notice to Alter a... OSD Federal Register Liaison Officer, Department of Defense. DWHS D01 System name: DoD National...
76 FR 3099 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2011-01-19
... DEPARTMENT OF DEFENSE Office of the Secretary [Docket ID: DOD-2011-OS-0006] Privacy Act of 1974; System of Records AGENCY: Office of the Secretary of Defense, DoD. ACTION: Notice to Add a System of...: January 11, 2011. Morgan F. Park, Alternate OSD Federal Register Liaison Officer, Department of Defense...
76 FR 76958 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2011-12-09
... DEPARTMENT OF DEFENSE Office of the Secretary [Docket ID: DOD-2011-OS-0141] Privacy Act of 1974; System of Records AGENCY: Office of the Secretary, Department of Defense (DoD). ACTION: Notice to Amend a... Siegel, Alternate OSD Federal Register Liaison Officer, Department of Defense. DWHS P18 System name...
32 CFR 806b.53 - Training tools.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 32 National Defense 6 2011-07-01 2011-07-01 false Training tools. 806b.53 Section 806b.53 National... Training § 806b.53 Training tools. Helpful resources include: (a) The Air Force Freedom of Information Act Web page which includes a Privacy Overview, Privacy Act training slides, the Air Force systems of...
Monoterpenes Support Systemic Acquired Resistance within and between Plants.
Riedlmeier, Marlies; Ghirardo, Andrea; Wenig, Marion; Knappe, Claudia; Koch, Kerstin; Georgii, Elisabeth; Dey, Sanjukta; Parker, Jane E; Schnitzler, Jörg-Peter; Vlot, A Corina
2017-06-01
This study investigates the role of volatile organic compounds in systemic acquired resistance (SAR), a salicylic acid (SA)-associated, broad-spectrum immune response in systemic, healthy tissues of locally infected plants. Gas chromatography coupled to mass spectrometry analyses of SAR-related emissions of wild-type and non-SAR-signal-producing mutant plants associated SAR with monoterpene emissions. Headspace exposure of Arabidopsis thaliana to a mixture of the bicyclic monoterpenes α-pinene and β-pinene induced defense, accumulation of reactive oxygen species, and expression of SA- and SAR-related genes, including the SAR regulatory AZELAIC ACID INDUCED1 ( AZI1 ) gene and three of its paralogs. Pinene-induced resistance was dependent on SA biosynthesis and signaling and on AZI1 Arabidopsis geranylgeranyl reductase1 mutants with reduced monoterpene biosynthesis were SAR-defective but mounted normal local resistance and methyl salicylate-induced defense responses, suggesting that monoterpenes act in parallel with SA The volatile emissions from SAR signal-emitting plants induced defense in neighboring plants, and this was associated with the presence of α-pinene, β-pinene, and camphene in the emissions of the "sender" plants. Our data suggest that monoterpenes, particularly pinenes, promote SAR, acting through ROS and AZI1 , and likely function as infochemicals in plant-to-plant signaling, thus allowing defense signal propagation between neighboring plants. © 2017 American Society of Plant Biologists. All rights reserved.
Defense Utility of Commercial Vessels and Craft.
1980-01-01
competence represented on this Committee include: ship design (naval architecture and marine engineering); marine transportation systems analysis; port...entire maritime industry, * including operators, designers , shipbuilders, suppliers, regulators, and researchers. This report was developed by a...larger commercial vessels now included in military contingency planning or the specially designed ships of the U.S. Navy and U.S. Coast Guard. 0 The
2013-12-13
To promote innovation , the role of the Defense Advanced Research Projects Agency should be expanded to include prototyping and other advanced...the requirements for the degree MASTER OF MILITARY ART AND SCIENCE Military History by MICHAEL G. KING, LCDR, USN B.S., Lees-McRae...NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) LCDR Michael G. King, USN 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7
1987-01-01
enough to sustain one wartime station overseas as well as satisfy training and maintenance needs. Advanced TacticalAir Reconnaissance System ( ATARS ...The ATARS is an umbrella concept for a series of upgrades in tactical reconnaissance capabilities. Major elements of the program include the Tactical...Funding Funding Funding E-3A Modifkation Development: $ Millions 105.2 96.8 110.7 88.4 Procurement: Quantity - - - - $ Millions .9 33.5 27.7 40.7 ATARS
Federal Register 2010, 2011, 2012, 2013, 2014
2013-10-24
... DEPARTMENT OF DEFENSE Defense Acquisition Regulations System [Docket Number DARS-2013-0035] Information Collection Requirement; Defense Federal Acquisition Regulation Supplement; Organizational Conflict..., Department of Defense (DoD). ACTION: Notice and request for comments regarding a proposed extension of an...
32 CFR 37.925 - What requirements do I include for termination and enforcement?
Code of Federal Regulations, 2010 CFR
2010-07-01
... to Other Administrative Matters Termination and Enforcement § 37.925 What requirements do I include... 32 National Defense 1 2010-07-01 2010-07-01 false What requirements do I include for termination and enforcement? 37.925 Section 37.925 National Defense Department of Defense OFFICE OF THE SECRETARY...
32 CFR 37.925 - What requirements do I include for termination and enforcement?
Code of Federal Regulations, 2011 CFR
2011-07-01
... to Other Administrative Matters Termination and Enforcement § 37.925 What requirements do I include... 32 National Defense 1 2011-07-01 2011-07-01 false What requirements do I include for termination and enforcement? 37.925 Section 37.925 National Defense Department of Defense OFFICE OF THE SECRETARY...
5 CFR 3601.102 - Designation of separate agency components.
Code of Federal Regulations, 2011 CFR
2011-01-01
... Service; (8) Defense Information Systems Agency; (9) Defense Intelligence Agency; (10) Defense Logistics... ETHICAL CONDUCT FOR EMPLOYEES OF THE DEPARTMENT OF DEFENSE § 3601.102 Designation of separate agency...
48 CFR 201.170 - Peer Reviews.
Code of Federal Regulations, 2011 CFR
2011-10-01
... Section 201.170 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT... Peer Reviews, the military departments, defense agencies, and DoD field activities shall provide a... departments, defense agencies, and DoD field activities shall establish procedures for— (1) Pre-award Peer...
48 CFR 201.170 - Peer Reviews.
Code of Federal Regulations, 2010 CFR
2010-10-01
... Section 201.170 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT... Peer Reviews, the military departments, defense agencies, and DoD field activities shall provide a... departments, defense agencies, and DoD field activities shall establish procedures for— (1) Pre-award Peer...
Evolution of System Safety at NASA as Related to Defense-in-Depth
NASA Technical Reports Server (NTRS)
Dezfuli, Homayoon
2015-01-01
Presentation given at the Defense-in-Depth Inter-Agency Workshop on August 26, 2015 in Rockville, MD by Homayoon Dezfuli. The presentation addresses the evolution of system safety at NASA as related to Defense-in-Depth.
5 CFR 9901.356 - Pay retention.
Code of Federal Regulations, 2010 CFR
2010-01-01
... Administrative Personnel DEPARTMENT OF DEFENSE HUMAN RESOURCES MANAGEMENT AND LABOR RELATIONS SYSTEMS (DEPARTMENT OF DEFENSE-OFFICE OF PERSONNEL MANAGEMENT) DEPARTMENT OF DEFENSE NATIONAL SECURITY PERSONNEL SYSTEM... employee who would not be affected personally requests a reduction in band; (ii) Management determines the...
48 CFR 235.010 - Scientific and technical reports.
Code of Federal Regulations, 2014 CFR
2014-10-01
... reports. 235.010 Section 235.010 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE SPECIAL CATEGORIES OF CONTRACTING RESEARCH AND DEVELOPMENT CONTRACTING 235.010 Scientific and technical reports. (b) For DoD, the Defense Technical Information Center is...
48 CFR 235.010 - Scientific and technical reports.
Code of Federal Regulations, 2010 CFR
2010-10-01
... reports. 235.010 Section 235.010 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE SPECIAL CATEGORIES OF CONTRACTING RESEARCH AND DEVELOPMENT CONTRACTING 235.010 Scientific and technical reports. (b) For DoD, the Defense Technical Information Center is...
48 CFR 235.010 - Scientific and technical reports.
Code of Federal Regulations, 2012 CFR
2012-10-01
... reports. 235.010 Section 235.010 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE SPECIAL CATEGORIES OF CONTRACTING RESEARCH AND DEVELOPMENT CONTRACTING 235.010 Scientific and technical reports. (b) For DoD, the Defense Technical Information Center is...
Code of Federal Regulations, 2013 CFR
2013-10-01
... 230.201-5 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF... 230.201-5 Waiver. (a)(1)(A) The military departments and the Director, Defense Procurement and... waiver requests to the Director, Defense Procurement and Acquisition Policy. (2) The military departments...
48 CFR 235.010 - Scientific and technical reports.
Code of Federal Regulations, 2013 CFR
2013-10-01
... reports. 235.010 Section 235.010 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE SPECIAL CATEGORIES OF CONTRACTING RESEARCH AND DEVELOPMENT CONTRACTING 235.010 Scientific and technical reports. (b) For DoD, the Defense Technical Information Center is...
48 CFR 235.010 - Scientific and technical reports.
Code of Federal Regulations, 2011 CFR
2011-10-01
... reports. 235.010 Section 235.010 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE SPECIAL CATEGORIES OF CONTRACTING RESEARCH AND DEVELOPMENT CONTRACTING 235.010 Scientific and technical reports. (b) For DoD, the Defense Technical Information Center is...
5 CFR 9901.407 - Minimum period of performance.
Code of Federal Regulations, 2010 CFR
2010-01-01
... Section 9901.407 Administrative Personnel DEPARTMENT OF DEFENSE HUMAN RESOURCES MANAGEMENT AND LABOR RELATIONS SYSTEMS (DEPARTMENT OF DEFENSE-OFFICE OF PERSONNEL MANAGEMENT) DEPARTMENT OF DEFENSE NATIONAL SECURITY PERSONNEL SYSTEM (NSPS) Performance Management § 9901.407 Minimum period of performance. (a) Only...
5 CFR 9901.406 - Setting and communicating performance expectations.
Code of Federal Regulations, 2010 CFR
2010-01-01
... expectations. 9901.406 Section 9901.406 Administrative Personnel DEPARTMENT OF DEFENSE HUMAN RESOURCES MANAGEMENT AND LABOR RELATIONS SYSTEMS (DEPARTMENT OF DEFENSE-OFFICE OF PERSONNEL MANAGEMENT) DEPARTMENT OF DEFENSE NATIONAL SECURITY PERSONNEL SYSTEM (NSPS) Performance Management § 9901.406 Setting and...
Code of Federal Regulations, 2010 CFR
2010-01-01
... Administrative Personnel DEPARTMENT OF DEFENSE HUMAN RESOURCES MANAGEMENT AND LABOR RELATIONS SYSTEMS (DEPARTMENT OF DEFENSE-OFFICE OF PERSONNEL MANAGEMENT) DEPARTMENT OF DEFENSE NATIONAL SECURITY PERSONNEL SYSTEM... meaning given that term in § 9901.103. Classification, also referred to as job evaluation, means the...