Advances in Cryptology - EUROCRYPT’ 97

DTIC Science & Technology

1998-05-03

public keys is about T/102. For example, one can choose T ~ 227.67 and M ~ 2 35.65. To obtain the secret session key from the determined internal state...scenario, where the objective is to reconstruct the secret key controlled LFSR initial states from the known keystream sequence, for a survey see... the secret message keys defining different initial internal states. This may open new possibilities for the secret key recovery cryptanalytic attacks

[Indicators monitoring the process of specialized nutritional support. Grupo de Nutrición de la SEFH].

PubMed

Sirvent, Mariola; Victoria Calvo, María; Sagalés, María; Rodríguez-Penin, Isaura; Cervera, Mercedes; Piñeiro, Guadalupe; García-Rodicio, Sonsoles; Gomis, Pilar; Caba, Isabel; Vazquez, Amparo; Gomez, María E; Pedraza, Luis

2013-01-01

To identify and develop monitoring indicators of the process of specialized nutritional support that will allow measuring the level of adherence to the established practice standards. Those practice standards considered to be key elements of the process were selected to develop performance indicators. The construction of these indicators combined the scientific evidence with expert opinion. Key goals were identified within each standard provided that its consecution would allow increasing the achievement of the standard. Particular improvement initiatives associated to each key goal were generated. Lastly, monitoring indicators were defined allowing undertaking a follow-up of the implementation of the improvement initiatives or either to assess the level of achievement of the key goals identified. Nineteen practice standards were selected representative of the critical points of the process. The strategic map for each standard has been defined, with the identification of 43 key goals. In order to achieve these key goals, a portfolio of improvements has been generated comprising 56 actions. Finally, 44 monitoring indicators have been defined grouped into three categories: 1. Numeric: they assess the level of goal achievement; 2. Dichotomic (yes/no): they inform on the execution of the improvement actions; 3. Results of the practice audits. We have made available monitoring indicators that allow assessing the level of adherence to the practice standards of the process of specialized nutritional support and the impact of the implementation of improvement actions within this process. Copyright © 2013 SEFH. Published by AULA MEDICA. All rights reserved.

Detecting unexpected variables in the MMPI 2 Social Introversion scale.

PubMed

Chang, C H; Wright, B D

2001-01-01

The standard scoring structure of the revised Minnesota Multiphasic Personality Inventory (MMPI-2) Social Introversion (Si) scale was reexamined with Rasch Measurement. The 69-item Si scale split into two distinct dimensions when their standardized residuals were factor analyzed. Items keyed "true" to Si defined one dimension and items keyed "false" defined another. Relationships between Lexile values (an index of reading difficulty and comprehension) and item difficulties were also explored. The article shows how to use Rasch Measurement to understand and improve personality assessment.

Another Strategy for Teaching Histology to A&P Students: Classification versus Memorization.

ERIC Educational Resources Information Center

Bavis, Ryan W.; Seveyka, Jerred; Shigeoka, Cassie A.

2000-01-01

Defines dichotomous keys as common learning tools based on identification rather than memorization. Provides an example of a dichotomous key developed for introducing histology in human anatomy and physiology (A&P) courses and explains how students can use the dichotomous key. Discusses the goals of the exercises and the process of…

Pricing and Fee Management.

ERIC Educational Resources Information Center

Fischer, Richard B.

1986-01-01

Defines key terms and discusses things to consider when setting fees for a continuing education program. These include (1) the organization's philosophy and mission, (2) certain key variables, (3) pricing strategy options, and (4) the test of reasonableness. (CH)

40 CFR 370.66 - How are key words in this part defined?

Code of Federal Regulations, 2010 CFR

2010-07-01

... unstable reactive, organic peroxide, and water reactive (as defined under 29 CFR 1910.1200). Hazardous... agricultural operations or is a fertilizer held for sale by a retailer to the ultimate customer. Indian Country...

Constructivist Learning Environments and Defining the Online Learning Community

ERIC Educational Resources Information Center

Brown, Loren

2014-01-01

The online learning community is frequently referred to, but ill defined. The constructivist philosophy and approach to teaching and learning is both an effective means of constructing an online learning community and it is a tool by which to define key elements of the learning community. In order to build a nurturing, self-sustaining online…

Defining Sex and Abstinence: Dialogue Is the Key

ERIC Educational Resources Information Center

Hamill, Shelley D.; Chepko, Stevie

2005-01-01

When does abstinence end and sexual activity begin? In previous generations, the continuum of sexual activity was well-defined in the old baseball analogy. Teens, parents, and teachers knew what going to first, second, or third base involved. For the current generation of young people, sex and abstinence are not so well-defined. As parents and…

An illustrated key to the genera and subgenera of the Recent azooxanthellate Scleractinia (Cnidaria, Anthozoa), with an attached glossary.

PubMed

Cairns, Stephen D; Kitahara, Marcelo V

2012-01-01

The 120 presently recognized genera and seven subgenera of the azooxanthellate Scleractinia are keyed using gross morphological characters of the corallum. All genera are illustrated with calicular and side views of coralla. All termes used in the key are defined in an illustrated glossary. A table of all species-level keys, both comprehensive and faunistic, is provided covering the last 40 years.

Definition of the Mediterranean Diet; a Literature Review.

PubMed

Davis, Courtney; Bryan, Janet; Hodgson, Jonathan; Murphy, Karen

2015-11-05

Numerous studies over several decades suggest that following the Mediterranean diet (MedDiet) can reduce the risk of cardiovascular disease and cancer, and improve cognitive health. However, there are inconsistencies among methods used for evaluating and defining the MedDiet. Through a review of the literature, we aimed to quantitatively define the MedDiet by food groups and nutrients. Databases PubMed, MEDLINE, Science Direct, Academic Search Premier and the University of South Australia Library Catalogue were searched. Articles were included if they defined the MedDiet in at least two of the following ways: (1) general descriptive definitions; (2) diet pyramids/numbers of servings of key foods; (3) grams of key foods/food groups; and (4) nutrient and flavonoid content. Quantity of key foods and nutrient content was recorded and the mean was calculated. The MedDiet contained three to nine serves of vegetables, half to two serves of fruit, one to 13 serves of cereals and up to eight serves of olive oil daily. It contained approximately 9300 kJ, 37% as total fat, 18% as monounsaturated and 9% as saturated, and 33 g of fibre per day. Our results provide a defined nutrient content and range of servings for the MedDiet based on past and current literature. More detailed reporting amongst studies could refine the definition further.

Defining the public, defining sociology: hybrid science-public relations and boundary-work in early American sociology.

PubMed

Evans, Michael S

2009-01-01

In this paper, I examine how scientific disciplines define their boundaries by defining the publics with whom they engage. The case study is an episode in the development of early American sociology. In response to the dual challenge of credibility set up by the conflict between religious Baconian science and secular positivist science, key actors engaged in specific strategies of boundary-work to create their desired "sociological public"--a hybrid form of science-public relations that appealed to hostile university scientists while excluding a supportive religious audience from participation in the production of scientific knowledge. Using this case, I offer two specific insights. First I illustrate how, in the pursuit of scientific credibility, actors engage in boundary-work to differentiate audiences, not just practitioners. Such defining of publics is constitutive of scientific disciplines in their formative stage. Second, I demonstrate how audience boundaries can be redefined through the capture of existing boundary objects. Specifically, the removal of informational content in key boundary objects creates durable boundaries that are difficult to overcome.

The national strategy for the physical protection of critical infrastructures and key assets

DOT National Transportation Integrated Search

2003-02-01

This document defines the road ahead for a core mission area identified in the President's National Strategy for Homeland Security-reducing the Nation's vulnerability to acts of terrorism by protecting our critical infrastructures and key assets from...

Did You Remember to DID

DTIC Science & Technology

2010-04-01

threats (also known as a SWOT analysis) is a very useful method in identifying potential issues, hidden agendas, and competing egos. • Defining a...comprehensive communications plan uses what’s been defined and informs (the second key component to DID) government and con - tractor teams of the essential...program execution strategies. Inform Inform means communicating to internal and external stake- holders what was defined, expected, discovered, con

Direct and reverse secret-key capacities of a quantum channel.

PubMed

Pirandola, Stefano; García-Patrón, Raul; Braunstein, Samuel L; Lloyd, Seth

2009-02-06

We define the direct and reverse secret-key capacities of a memoryless quantum channel as the optimal rates that entanglement-based quantum-key-distribution protocols can reach by using a single forward classical communication (direct reconciliation) or a single feedback classical communication (reverse reconciliation). In particular, the reverse secret-key capacity can be positive for antidegradable channels, where no forward strategy is known to be secure. This property is explicitly shown in the continuous variable framework by considering arbitrary one-mode Gaussian channels.

Lifelong Learning Key Competence Levels of Graduate Students

ERIC Educational Resources Information Center

Adabas, Abdurrahman; Kaygin, Hüseyin

2016-01-01

The European Union defines lifelong learning as all activities aimed at improving an individual's knowledge, skills and competences individually, socially or vocationally throughout his/her life. In 2007, eight key competences necessary for lifelong learning were identified by the European Union Education and Culture Commission. These competences…

Dose and Effect Thresholds for Early Key Events in a Mode of PPARa-Mediated Action

EPA Science Inventory

ABSTRACT Strategies for predicting adverse health outcomes of environmental chemicals are centered on early key events in toxicity pathways. However, quantitative relationships between early molecular changes in a given pathway and later health effects are often poorly defined. T...

Optimising diagnosis of viraemic hepatitis C infection: the development of a target product profile.

PubMed

Ivanova Reipold, Elena; Easterbrook, Philippa; Trianni, Alessandra; Panneer, Nivedha; Krakower, Douglas; Ongarello, Stefano; Roberts, Teri; Miller, Veronica; Denkinger, Claudia

2017-11-01

The current low access to virological testing to confirm chronic viraemic HCV infection in low- and middle-income countries (LMIC) is limiting the rollout of hepatitis C (HCV) care. Existing tests are complex, costly and require sophisticated laboratory infrastructure. Diagnostic manufacturers need guidance on the optimal characteristics a virological test needs to have to ensure the greatest impact on HCV diagnosis and treatment in LMIC. Our objective was to develop a target product profile (TPP) for diagnosis of HCV viraemia using a global stakeholder consensus-based approach. Based on the standardised process established to develop consensus-based TPPs, we followed five key steps. (i) Identifying key potential global stakeholders for consultation and input into the TPP development process. (ii) Informal priority-setting exercise with key experts to identify the needs that should be the highest priority for the TPP development; (iii) Defining the key TPP domains (scope, performance and operational characteristics and price). (iv) Delphi-like process with larger group of key stakeholder to facilitate feedback on the key TPP criteria and consensus building based on pre-defined consensus criteria. (v) A final consensus-gathering meeting for discussions around disputed criteria. A complementary values and preferences survey helped to assess trade-offs between different key characteristics. The following key attributes for the TPP for a test to confirm HCV viraemic infection were identified: The scope defined is for both HCV detection as well as confirmation of cure. The timeline of development for tests envisioned in the TPP is 5 years. The test should be developed for use by health-care workers or laboratory technicians with limited training in countries with a medium to high prevalence of HCV (1.5-3.5% and >3.5%) and in high-risk populations in low prevalence settings (<1.5%). A clinical sensitivity at a minimum of 90% is considered sufficient (analytical sensitivity of the equivalent of 3000 IU/ml), particularly if the test increases access to testing through an affordable price, increase ease-of-use and feasibility on capillary blood. Polyvalency would be optimal (i.e. ability to test for HIV and others). The only characteristic that full agreement could not be achieved on was the price for a virological test. Discussants felt that to reach the optimal target price substantial trade-offs had to be made (e.g. in regards to sensitivity and integration). The TPP and V&P survey results define the need for an easy-to-use, low cost test to increase access to diagnosis and linkage to care in LMIC.

Understanding the Emergence of Disruptive Innovation in Air Force Science and Technology Organizations

DTIC Science & Technology

2008-03-01

respect to various key attributes. Although the principles of low-end and new market disruption play the most significant role in the fluid and...crucial role in the emergence of breakthrough and game changing ideas. By examining these key elements with regard to industry innovation, a base...that help define the key characteristics of an innovative culture: strong customer focus, collaboration, effective processes , creative people

Key-and-keyway coupling for transmitting torque

DOEpatents

Blue, S.C.; Curtis, M.T.; Orthwein, W.C.; Stitt, D.H.

1975-11-18

The design of an improved key-and-keyway coupling for the transmission of torque is given. The coupling provides significant reductions in stress concentrations in the vicinity of the key and keyway. The keyway is designed with a flat-bottomed u-shaped portion whose inboard end terminates in a ramp which is dished transversely, so that the surface of the ramp as viewed in transverse section defines an outwardly concave arc.

Why and how might genetic and phylogenetic diversity be reflected in the identification of key biodiversity areas?

PubMed

Brooks, T M; Cuttelod, A; Faith, D P; Garcia-Moreno, J; Langhammer, P; Pérez-Espona, S

2015-02-19

'Key biodiversity areas' are defined as sites contributing significantly to the global persistence of biodiversity. The identification of these sites builds from existing approaches based on measures of species and ecosystem diversity and process. Here, we therefore build from the work of Sgró et al. (2011 Evol. Appl. 4, 326-337. (doi:10.1111/j.1752-4571.2010.00157.x)) to extend a framework for how components of genetic diversity might be considered in the identification of key biodiversity areas. We make three recommendations to inform the ongoing process of consolidating a key biodiversity areas standard: (i) thresholds for the threatened species criterion currently consider a site's share of a threatened species' population; expand these to include the proportion of the species' genetic diversity unique to a site; (ii) expand criterion for 'threatened species' to consider 'threatened taxa' and (iii) expand the centre of endemism criterion to identify as key biodiversity areas those sites holding a threshold proportion of the compositional or phylogenetic diversity of species (within a taxonomic group) whose restricted ranges collectively define a centre of endemism. We also recommend consideration of occurrence of EDGE species (i.e. threatened phylogenetic diversity) in key biodiversity areas to prioritize species-specific conservation actions among sites.

Patients’ Data Management System Protected by Identity-Based Authentication and Key Exchange

PubMed Central

Rivero-García, Alexandra; Santos-González, Iván; Hernández-Goya, Candelaria; Caballero-Gil, Pino; Yung, Moti

2017-01-01

A secure and distributed framework for the management of patients’ information in emergency and hospitalization services is proposed here in order to seek improvements in efficiency and security in this important area. In particular, confidentiality protection, mutual authentication, and automatic identification of patients are provided. The proposed system is based on two types of devices: Near Field Communication (NFC) wristbands assigned to patients, and mobile devices assigned to medical staff. Two other main elements of the system are an intermediate server to manage the involved data, and a second server with a private key generator to define the information required to protect communications. An identity-based authentication and key exchange scheme is essential to provide confidential communication and mutual authentication between the medical staff and the private key generator through an intermediate server. The identification of patients is carried out through a keyed-hash message authentication code. Thanks to the combination of the aforementioned tools, a secure alternative mobile health (mHealth) scheme for managing patients’ data is defined for emergency and hospitalization services. Different parts of the proposed system have been implemented, including mobile application, intermediate server, private key generator and communication channels. Apart from that, several simulations have been performed, and, compared with the current system, significant improvements in efficiency have been observed. PMID:28362328

Why and how might genetic and phylogenetic diversity be reflected in the identification of key biodiversity areas?

PubMed Central

Brooks, T. M.; Cuttelod, A.; Faith, D. P.; Garcia-Moreno, J.; Langhammer, P.; Pérez-Espona, S.

2015-01-01

‘Key biodiversity areas' are defined as sites contributing significantly to the global persistence of biodiversity. The identification of these sites builds from existing approaches based on measures of species and ecosystem diversity and process. Here, we therefore build from the work of Sgró et al. (2011 Evol. Appl. 4, 326–337. (doi:10.1111/j.1752-4571.2010.00157.x)) to extend a framework for how components of genetic diversity might be considered in the identification of key biodiversity areas. We make three recommendations to inform the ongoing process of consolidating a key biodiversity areas standard: (i) thresholds for the threatened species criterion currently consider a site's share of a threatened species' population; expand these to include the proportion of the species' genetic diversity unique to a site; (ii) expand criterion for ‘threatened species' to consider ‘threatened taxa’ and (iii) expand the centre of endemism criterion to identify as key biodiversity areas those sites holding a threshold proportion of the compositional or phylogenetic diversity of species (within a taxonomic group) whose restricted ranges collectively define a centre of endemism. We also recommend consideration of occurrence of EDGE species (i.e. threatened phylogenetic diversity) in key biodiversity areas to prioritize species-specific conservation actions among sites. PMID:25561678

Patients' Data Management System Protected by Identity-Based Authentication and Key Exchange.

PubMed

Rivero-García, Alexandra; Santos-González, Iván; Hernández-Goya, Candelaria; Caballero-Gil, Pino; Yung, Moti

2017-03-31

A secure and distributed framework for the management of patients' information in emergency and hospitalization services is proposed here in order to seek improvements in efficiency and security in this important area. In particular, confidentiality protection, mutual authentication, and automatic identification of patients are provided. The proposed system is based on two types of devices: Near Field Communication (NFC) wristbands assigned to patients, and mobile devices assigned to medical staff. Two other main elements of the system are an intermediate server to manage the involved data, and a second server with a private key generator to define the information required to protect communications. An identity-based authentication and key exchange scheme is essential to provide confidential communication and mutual authentication between the medical staff and the private key generator through an intermediate server. The identification of patients is carried out through a keyed-hash message authentication code. Thanks to the combination of the aforementioned tools, a secure alternative mobile health (mHealth) scheme for managing patients' data is defined for emergency and hospitalization services. Different parts of the proposed system have been implemented, including mobile application, intermediate server, private key generator and communication channels. Apart from that, several simulations have been performed, and, compared with the current system, significant improvements in efficiency have been observed.

40 CFR 355.61 - How are key words in this part defined?

Code of Federal Regulations, 2011 CFR

2011-07-01

... includes manmade structures, as well as all natural structures in which chemicals are purposefully placed... agricultural products during a year. Hazardous chemical means any hazardous chemical as defined under 29 CFR... of a technically qualified individual; or (iii) In routine agricultural operations or is a fertilizer...

40 CFR 355.61 - How are key words in this part defined?

Code of Federal Regulations, 2014 CFR

2014-07-01

... includes manmade structures, as well as all natural structures in which chemicals are purposefully placed... agricultural products during a year. Hazardous chemical means any hazardous chemical as defined under 29 CFR... of a technically qualified individual; or (iii) In routine agricultural operations or is a fertilizer...

Results of availability imposed configuration details developed for K-DEMO

DOE PAGES

Brown, Tom; Titus, Peter; Brooks, Art; ...

2016-02-05

We completed a two year study using the Korean fusion demonstration reactor (K-DEMO) where we looked at key Tokamak components and configuration options in preparation of a conceptual design phase. A key part of a device configuration centers on defining an arrangement that enhances the ability to reach high availability values by defining design solutions that foster simplified maintenance operations. In order to maximize the size and minimize the number of in-vessel components enlarged TF coils were defined that incorporate a pair of windings within each coil to mitigate pressure drop issues and to reduce the cost of the coils.more » Furthermore, we defined a semi-permanent shield structure in order to develop labyrinth interfaces between double-null plasma contoured shield modules, provide an entity to align blanket components and provide support against disruption loads—with a load path that equilibrates blanket, TF and PF loads through a base structure. Blanket piping services and auxiliary systems that interface with in-vessel components have played a major role in defining the overall device arrangement—concept details will be presented along with general arrangement features and preliminary results obtained from disruption analysis.« less

Key Data on Education in Europe 2009

ERIC Educational Resources Information Center

Ranguelov, Stanislav; de Coster, Isabelle; Forsthuber, Bernadette; Noorani, Sogol; Ruffio, Philippe

2009-01-01

This seventh edition of "Key Data on Education in Europe" retains its main special feature which is the combination of statistical data and qualitative information to describe the organisation and functioning of education systems in Europe. The present 2009 edition maintains the subject-based structure defined by the previous one but…

Identifying the Key Concerns of Irish Persons with Intellectual Disability

ERIC Educational Resources Information Center

García Iriarte, Edurne; O'Brien, Patricia; McConkey, Roy; Wolfe, Marie; O'Doherty, Siobhain

2014-01-01

Background: Internationally, people with intellectual disability are socially marginalized, and their rights under the United Nations Convention for the Rights of Persons with Disabilities (CRPD) are often ignored. Aims: This paper aims to define the key concerns of adults with an intellectual disability in relation to their participation in…

Keys to Success in Raising Funds: An Exchange Classic.

ERIC Educational Resources Information Center

Neugebauer, Roger

2001-01-01

Details survey of over 100 child care centers about successful and unsuccessful fundraising projects. Highlights ten key factors contributing to success: defining the purpose for fundraising, setting a goal, knowing the audience, making it fun, building on strengths, looking for repeated fundraisers, being cost effective, publicizing aggressively,…

Using Key Performance Indicators to Drive Strategic Decision Making.

ERIC Educational Resources Information Center

Dolence, Michael G.; Norris, Donald M.

1994-01-01

A nine-step method for defining and pursuing key performance indicators (KPIs), derived from a strategic planning process, is outlined, and its applications at the University of Northern Colorado and Illinois Benedictine College are described and tabulated. A chart summarizes current and projected KPIs for Illinois Benedictine College for each…

Russian Quality Assessment System in Education: Key Lessons

ERIC Educational Resources Information Center

Bolotov, V.; Valdman, I.; Kovaleva, G.; Pinskaya, M.

2015-01-01

This article examines key lessons learned by Russia while developing national assessment system in education. It shows that reforms are more likely to succeed backed with sustained political support, clearly defined goals or priorities, gradual introduction, and open discussion with stakeholders. [This article was translated by Lucy Gunderson.

49 CFR 236.1033 - Communications and security requirements.

Code of Federal Regulations, 2011 CFR

2011-10-01

... shall: (1) Use an algorithm approved by the National Institute of Standards (NIST) or a similarly...; or (ii) When the key algorithm reaches its lifespan as defined by the standards body responsible for approval of the algorithm. (c) The cleartext form of the cryptographic keys shall be protected from...

49 CFR 236.1033 - Communications and security requirements.

Code of Federal Regulations, 2014 CFR

2014-10-01

... shall: (1) Use an algorithm approved by the National Institute of Standards (NIST) or a similarly...; or (ii) When the key algorithm reaches its lifespan as defined by the standards body responsible for approval of the algorithm. (c) The cleartext form of the cryptographic keys shall be protected from...

49 CFR 236.1033 - Communications and security requirements.

Code of Federal Regulations, 2013 CFR

2013-10-01

... shall: (1) Use an algorithm approved by the National Institute of Standards (NIST) or a similarly...; or (ii) When the key algorithm reaches its lifespan as defined by the standards body responsible for approval of the algorithm. (c) The cleartext form of the cryptographic keys shall be protected from...

49 CFR 236.1033 - Communications and security requirements.

Code of Federal Regulations, 2012 CFR

2012-10-01

... shall: (1) Use an algorithm approved by the National Institute of Standards (NIST) or a similarly...; or (ii) When the key algorithm reaches its lifespan as defined by the standards body responsible for approval of the algorithm. (c) The cleartext form of the cryptographic keys shall be protected from...

49 CFR 236.1033 - Communications and security requirements.

Code of Federal Regulations, 2010 CFR

2010-10-01

... shall: (1) Use an algorithm approved by the National Institute of Standards (NIST) or a similarly...; or (ii) When the key algorithm reaches its lifespan as defined by the standards body responsible for approval of the algorithm. (c) The cleartext form of the cryptographic keys shall be protected from...

Mars rover/sample return mission requirements affecting space station

NASA Technical Reports Server (NTRS)

1988-01-01

The possible interfaces between the Space Station and the Mars Rover/Sample Return (MRSR) mission are defined. In order to constrain the scope of the report a series of seven design reference missions divided into three major types were assumed. These missions were defined to span the probable range of Space Station-MRSR interactions. The options were reduced, the MRSR sample handling requirements and baseline assumptions about the MRSR hardware and the key design features and requirements of the Space Station are summarized. Only the aspects of the design reference missions necessary to define the interfaces, hooks and scars, and other provisions on the Space Station are considered. An analysis of each of the three major design reference missions, is reported, presenting conceptual designs of key hardware to be mounted on the Space Station, a definition of weights, interfaces, and required hooks and scars.

Definition ofthe Design Trajectory and Entry Flight Corridor for the NASA Orion Exploration Mission 1 Entry Trajectory Using an Integrated Approach and Optimization

NASA Technical Reports Server (NTRS)

McNamara, Luke W.; Braun, Robert D.

2014-01-01

One of the key design objectives of NASA's Orion Exploration Mission 1 (EM- 1) is to execute a guided entry trajectory demonstrating GN&C capability. The focus of this paper is defining the flyable entry corridor for EM-1 taking into account multiple subsystem constraints such as complex aerothermal heating constraints, aerothermal heating objectives, landing accuracy constraints, structural load limits, Human-System-Integration-Requirements, Service Module debris disposal limits and other flight test objectives. During the EM-1 Design Analysis Cycle 1 design challenges came up that made defining the flyable entry corridor for the EM-1 mission critical to mission success. This document details the optimization techniques that were explored to use with the 6-DOF ANTARES simulation to assist in defining the design entry interface state and entry corridor with respect to key flight test constraints and objectives.

Why There Are 88 Keys on the Piano: "88 Logic-The Mackay Method for Piano." Volume 1

ERIC Educational Resources Information Center

Mackay, Stephen R.

2005-01-01

Background: After trying to define the reason why the piano ended up with 88 keys, I found patterns to explain ways of playing the piano with an 8:8 ratio which gives purpose to why the piano has 88 keys on it. Purpose: The first purpose is to enable piano teachers and music students to benefit from understanding how to play piano and be…

Continuous-variable quantum key distribution protocols over noisy channels.

PubMed

García-Patrón, Raúl; Cerf, Nicolas J

2009-04-03

A continuous-variable quantum key distribution protocol based on squeezed states and heterodyne detection is introduced and shown to attain higher secret key rates over a noisy line than any other one-way Gaussian protocol. This increased resistance to channel noise can be understood as resulting from purposely adding noise to the signal that is converted into the secret key. This notion of noise-enhanced tolerance to noise also provides a better physical insight into the poorly understood discrepancies between the previously defined families of Gaussian protocols.

SDMS: A scientific data management system

NASA Technical Reports Server (NTRS)

Massena, W. A.

1978-01-01

SDMS is a data base management system developed specifically to support scientific programming applications. It consists of a data definition program to define the forms of data bases, and FORTRAN-compatible subroutine calls to create and access data within them. Each SDMS data base contains one or more data sets. A data set has the form of a relation. Each column of a data set is defined to be either a key or data element. Key elements must be scalar. Data elements may also be vectors or matrices. The data elements in each row of the relation form an element set. SDMS permits direct storage and retrieval of an element set by specifying the corresponding key element values. To support the scientific environment, SDMS allows the dynamic creation of data bases via subroutine calls. It also allows intermediate or scratch data to be stored in temporary data bases which vanish at job end.

A Framework for Defining and Assessing Occupational and Training Standards in Developing Countries. Information Series.

ERIC Educational Resources Information Center

Fretwell, David H.; Lewis, Morgan V.; Deij, Arjen

The key issues, alternatives, and implications for developing countries to consider when designing systems to define occupational standards, related training standards, and assessments were analyzed. The analysis focused on the following issues: the rationale for development of standards; clarification of definitions, terminology, and assumptions;…

Emotional Literary: To Be a Different Kind of Smart.

ERIC Educational Resources Information Center

Bocchino, Rob

This book combines strategies and skills with theory and research to identify some of the key skills, maps, and tools that define emotional literacy. Emotional literacy is defined as having the skills to understand and manage emotions, to communicate effectively in order to become an autonomous person. The book focuses on the background and…

Finding the "Prism": Understanding Vygotsky's "Perezhivanie" as an Ontogenetic Unit of Child Consciousness

ERIC Educational Resources Information Center

Michell, Michael

2016-01-01

The concept of perezhivanie, Vygotsky's "last word" on psychology, has been among the most difficult of his theoretical constructs to define and operationalise in research. Drawing on close analysis of key texts, this article identifies and examines three defining attributes of "perezhivanie" found throughout Vygotsky's works.…

Defining and Measuring Engagement and Learning in Science: Conceptual, Theoretical, Methodological, and Analytical Issues

ERIC Educational Resources Information Center

Azevedo, Roger

2015-01-01

Engagement is one of the most widely misused and overgeneralized constructs found in the educational, learning, instructional, and psychological sciences. The articles in this special issue represent a wide range of traditions and highlight several key conceptual, theoretical, methodological, and analytical issues related to defining and measuring…

Strategic management of five deciduous forest invaders using Microstegium vimineum as a model species

Treesearch

Cynthia D. Huebner

2007-01-01

This paper links key plant invasive traits with key landscape traits to define strategic management for five common forest invaders, using empirical data of Microstegium vimineum dispersal into forests as a preliminary model. Microstegium vimineum exhibits an Allee effect that may allow management to focus on treating its source...

Key Events in Student Leaders' Lives and Lessons Learned from Them

ERIC Educational Resources Information Center

Sessa, Valerie I.; Morgan, Brett V.; Kalenderli, Selin; Hammond, Fanny E.

2014-01-01

This descriptive study used an interview protocol developed by the Center for Creative Leadership with 50 college student leaders to determine what key developmental events young college leaders experience and the leadership lessons learned from these events. Students discussed 180 events and 734 lessons learned from them. Most events defined by…

Effective Teaching: A Review of Research and Evidence

ERIC Educational Resources Information Center

Ko, James; Sammons, Pamela

2013-01-01

Teachers are one of the key elements in any school and effective teaching is one of the key propellers for school improvement. This review is concerned with how to define a teacher's effectiveness and what makes an effective teacher. It draws out implications for policymakers in education and for improving classroom practice. Teacher…

Terminology of European Education and Training Policy: A Selection of 130 Key Terms. Second Edition

ERIC Educational Resources Information Center

Cedefop - European Centre for the Development of Vocational Training, 2014

2014-01-01

This multilingual glossary defines 130 key terms used in European education and training policy. It is an extended and updated version of "Terminology of European education and training policy" (2008) and "Terminology of vocational training policy" (2004). It considers new priorities of European union policy, mainly in skills…

Arctic potential - Could more structured view improve the understanding of Arctic business opportunities?

NASA Astrophysics Data System (ADS)

Hintsala, Henna; Niemelä, Sami; Tervonen, Pekka

2016-09-01

The increasing interest towards the Arctic has been witnessed during the past decades. However, the commonly shared definitions of the Arctic key concepts have not yet penetrated national and international arenas for political and economic decision making. The lack of jointly defined framework has made different analyses related to the Arctic quite limited considering the magnitude of economic potential embedded in Arctic. This paper is built on the key findings of two separate, yet connected projects carried out in the Oulu region, Finland. In this paper's approach, the Arctic context has been defined as a composition of three overlapping layers. The first layer is the phenomenological approach to define the Arctic region. The second layer is the strategy-level analysis to define different Arctic paths as well as a national level description of a roadmap to Arctic specialization. The third layer is the operationalization of the first two layers to define the Arctic business context and business opportunities. The studied case from Oulu region indicates that alternative futures for the Arctic competences and business activities are in resemblance with only two of the four identified strategic pathways. Introduction of other pathways to regional level actors as credible and attractive options would require additional, systematic efforts.

The Core Competency Movement in Marriage and Family Therapy: Key Considerations from Other Disciplines

ERIC Educational Resources Information Center

Miller, John K.; Todahl, Jeff L.; Platt, Jason J.

2010-01-01

There is a growing movement to define competency within the field of marriage and family therapy (MFT), particularly with respect to the training of practitioners and the evaluation of clinical practice. Efforts to define competency, however, transcend the practice of MFT and much can be learned from the experiences of other disciplines.…

Finding and Developing Moderators and Directional Keys by Regression Analysis.

ERIC Educational Resources Information Center

Kokosh, John

A procedure for rapid screening of variables as potential moderators is presented and discussed. A moderator is defined as any variable which can be used to identify differentially predictable persons; or defined statistically by stating that if a predictor and a moderator are each divided into three or more categories and used as independent…

Toward an Explanation of Age Trends in Problem Behavior.

ERIC Educational Resources Information Center

Osgood, D. Wayne

Problem behavior may be defined as behavior that is socially defined as a problem, a source of concern, or as undesirable by the norms of conventional society and the institutions of adult authority, and its occurrence usually elicits some kind of social control response. Key elements of problem behavior are: (1) problem behaviors are rare until…

75 FR 972 - Nomination of Existing Marine Protected Areas to the National System of Marine Protected Areas

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-07

... key conservation gaps in important ocean areas. DATES: Comments on the nominations to the national... the Framework. Executive Order 13158 defines an MPA as: ``any area of the marine environment that has... national system may include both terrestrial and marine components, the term MPA as defined in the...

Analyzing Media: Metaphors as Methodologies.

ERIC Educational Resources Information Center

Meyrowitz, Joshua

Students have little intuitive insight into the process of thinking and structuring ideas. The image of metaphor for a phenomenon acts as a kind of methodology for the study of the phenomenon by (1) defining the key issues or problems; (2) shaping the type of research questions that are asked; (3) defining the type of data that are searched out;…

From Classroom to Workplace: An Exploration of How Teachers and Employers of Accounting Graduates Define and Assess Critical Thinking in Action

ERIC Educational Resources Information Center

Jagannathan, Christine

2017-01-01

Purpose: The purpose of this study was to explore how 2 important stakeholder groups of Southern California business education, regional faculty and employers of accounting graduates, defined and assessed critical thinking skills. Methods: A literature review identified 2 key variables--conceptualization and operational assessment of critical…

Buddy Tag CONOPS and Requirements.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Brotz, Jay Kristoffer; Deland, Sharon M.

2015-12-01

This document defines the concept of operations (CONOPS) and the requirements for the Buddy Tag, which is conceived and designed in collaboration between Sandia National Laboratories and Princeton University under the Department of State Key VerificationAssets Fund. The CONOPS describe how the tags are used to support verification of treaty limitations and is only defined to the extent necessary to support a tag design. The requirements define the necessary functions and desired non-functional features of the Buddy Tag at a high level

Focal Uncaging of GABA Reveals a Temporally Defined Role for GABAergic Inhibition during Appetitive Associative Olfactory Conditioning in Honeybees

ERIC Educational Resources Information Center

Raccuglia, Davide; Mueller, Uli

2013-01-01

Throughout the animal kingdom, the inhibitory neurotransmitter ?-aminobutyric acid (GABA) is a key modulator of physiological processes including learning. With respect to associative learning, the exact time in which GABA interferes with the molecular events of learning has not yet been clearly defined. To address this issue, we used two…

Defining "Knowledge" in Vocational Education Qualifications in England: An Analysis of Key Stakeholders and Their Constructions of Knowledge, Purposes and Content

ERIC Educational Resources Information Center

Bathmaker, Ann-Marie

2013-01-01

What is meant by "knowledge" in vocational education qualifications and who decides? These are significant questions in a context where "skill" is the prevailing discourse. This paper reports on a research project, undertaken in 2010-2011, which investigated the role of national stakeholders in defining knowledge in vocational…

75 FR 38779 - Nomination of Existing Marine Protected Areas to the National System of Marine Protected Areas

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-06

... managing agencies to fill key conservation gaps in important ocean areas. DATES: Comments on the... conservation objectives of the Framework. Executive Order 13158 defines an MPA as: ``any area of the marine... term MPA as defined in the Framework refers only to the marine portion of a site (below the mean high...

A Psychoanalytic Introduction to Reader Response to Racial Literature.

ERIC Educational Resources Information Center

Collins, Terence George

The essay defines and illustrates ways in which the anxiety of separation and the fantasy of dirt play a key role in shaping the response of readers to texts loosely defined as "racial." The work of Wheatley, Wright, and Baldwin, as well as that of some of the new black poets, is examined in relation to the psychoanalytic theories which…

Examining the recent climate through the lens of ecology: inferences from temporal pattern analysis.

Treesearch

Paul F. Hessburg; Ellen E. Kuhlmann; Thomas W. Swetnam

2005-01-01

Ecological theory asserts that the climate of a region exerts top-down controls on regional ecosystem patterns and processes, across space and time. To provide empirical evidence of climatic controls, it would be helpful to define climatic regions that minimized variance in key climate attributes, within climatic regions-define the periods and features of climatic...

Review of the Research Literature on Defining and Demonstrating Quality Teaching and Impact in Higher Education

ERIC Educational Resources Information Center

Strang, Lucy; Bélanger, Julie; Manville, Catriona; Meads, Catherine

2016-01-01

In March 2016, the Higher Education Academy (HEA) commissioned RAND Europe to conduct a literature review of research published since 2012, with the aim of identifying and summarising the key trends and issues in the literature on how "quality teaching" and its impact are currently being defined and demonstrated at higher education…

Impact of spatial organization on a novel auxotrophic interaction among soil microbes

DOE PAGES

Jiang, Xue; ZerfaB, Christian; Feng, Song; ...

2018-03-23

Here, a key prerequisite to achieve a deeper understanding of microbial communities and to engineer synthetic ones is to identify the individual metabolic interactions among key species and how these interactions are affected by different environmental factors. Deciphering the physiological basis of species–species and species–environment interactions in spatially organized environments requires reductionist approaches using ecologically and functionally relevant species. To this end, we focus here on a defined system to study the metabolic interactions in a spatial context among the plant-beneficial endophytic fungus Serendipita indica, and the soil-dwelling model bacterium Bacillus subtilis. Focusing on the growth dynamics of S. indicamore » under defined conditions, we identified an auxotrophy in this organism for thiamine, which is a key co-factor for essential reactions in the central carbon metabolism. We found that S. indica growth is restored in thiamine-free media, when co-cultured with B. subtilis. The success of this auxotrophic interaction, however, was dependent on the spatial and temporal organization of the system; the beneficial impact of B. subtilis was only visible when its inoculation was separated from that of S. indica either in time or space. These findings describe a key auxotrophic interaction in the soil among organisms that are shown to be important for plant ecosystem functioning, and point to the potential importance of spatial and temporal organization for the success of auxotrophic interactions. These points can be particularly important for engineering of minimal functional synthetic communities as plant seed treatments and for vertical farming under defined conditions.« less

The clinical academic workforce in Australia and New Zealand: report on the second binational summit to implement a sustainable training pathway.

PubMed

Windsor, John; Garrod, Tamsin; Talley, Nicholas J; Tebbutt, Carmel; Churchill, James; Farmer, Elizabeth; Baur, Louise; Smith, Julian A

2017-04-01

There has been a decline in the proportion of clinical academics compared with full-time clinicians, since 2004. A Working Party was established to help develop and implement a model for the training of clinical academics. After a highly successful first summit in 2014 that summarised the challenges faced by clinical academics in Australia and New Zealand, a second summit was convened late in 2015 to report on progress and to identify key areas for further action. The second summit provided survey results that identified the varied training pathways currently offered to clinical academics and the institutions willing to be involved in developing improved pathways. A literature review also described the contributions that clinical academics make to the health sector and the challenges faced by this workforce sector. Current training pathways created for clinical academics by Australasian institutions were presented as examples of what can be done. The perspectives of government and research organisations presented at the summit helped define how key stakeholders can contribute. Following the summit, there was a strong commitment to continue to work towards developing a sustainable and defined training pathway for clinical academics. The need for a coordinated and integrated approach was highlighted. Some key objectives were agreed upon for the next phase, including identifying and engaging key advocates within government and leading institutions; publishing and profiling the contributions of successful clinical academics to healthcare outcomes; defining the stages of a clinical academic training pathway; and establishing a mentoring programme for training clinical academics. © 2017 Royal Australasian College of Physicians.

Impact of spatial organization on a novel auxotrophic interaction among soil microbes.

PubMed

Jiang, Xue; Zerfaß, Christian; Feng, Song; Eichmann, Ruth; Asally, Munehiro; Schäfer, Patrick; Soyer, Orkun S

2018-06-01

A key prerequisite to achieve a deeper understanding of microbial communities and to engineer synthetic ones is to identify the individual metabolic interactions among key species and how these interactions are affected by different environmental factors. Deciphering the physiological basis of species-species and species-environment interactions in spatially organized environments requires reductionist approaches using ecologically and functionally relevant species. To this end, we focus here on a defined system to study the metabolic interactions in a spatial context among the plant-beneficial endophytic fungus Serendipita indica, and the soil-dwelling model bacterium Bacillus subtilis. Focusing on the growth dynamics of S. indica under defined conditions, we identified an auxotrophy in this organism for thiamine, which is a key co-factor for essential reactions in the central carbon metabolism. We found that S. indica growth is restored in thiamine-free media, when co-cultured with B. subtilis. The success of this auxotrophic interaction, however, was dependent on the spatial and temporal organization of the system; the beneficial impact of B. subtilis was only visible when its inoculation was separated from that of S. indica either in time or space. These findings describe a key auxotrophic interaction in the soil among organisms that are shown to be important for plant ecosystem functioning, and point to the potential importance of spatial and temporal organization for the success of auxotrophic interactions. These points can be particularly important for engineering of minimal functional synthetic communities as plant seed treatments and for vertical farming under defined conditions.

Impact of spatial organization on a novel auxotrophic interaction among soil microbes

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jiang, Xue; ZerfaB, Christian; Feng, Song

Here, a key prerequisite to achieve a deeper understanding of microbial communities and to engineer synthetic ones is to identify the individual metabolic interactions among key species and how these interactions are affected by different environmental factors. Deciphering the physiological basis of species–species and species–environment interactions in spatially organized environments requires reductionist approaches using ecologically and functionally relevant species. To this end, we focus here on a defined system to study the metabolic interactions in a spatial context among the plant-beneficial endophytic fungus Serendipita indica, and the soil-dwelling model bacterium Bacillus subtilis. Focusing on the growth dynamics of S. indicamore » under defined conditions, we identified an auxotrophy in this organism for thiamine, which is a key co-factor for essential reactions in the central carbon metabolism. We found that S. indica growth is restored in thiamine-free media, when co-cultured with B. subtilis. The success of this auxotrophic interaction, however, was dependent on the spatial and temporal organization of the system; the beneficial impact of B. subtilis was only visible when its inoculation was separated from that of S. indica either in time or space. These findings describe a key auxotrophic interaction in the soil among organisms that are shown to be important for plant ecosystem functioning, and point to the potential importance of spatial and temporal organization for the success of auxotrophic interactions. These points can be particularly important for engineering of minimal functional synthetic communities as plant seed treatments and for vertical farming under defined conditions.« less

An unsupervised method for summarizing egocentric sport videos

NASA Astrophysics Data System (ADS)

Habibi Aghdam, Hamed; Jahani Heravi, Elnaz; Puig, Domenec

2015-12-01

People are getting more interested to record their sport activities using head-worn or hand-held cameras. This type of videos which is called egocentric sport videos has different motion and appearance patterns compared with life-logging videos. While a life-logging video can be defined in terms of well-defined human-object interactions, notwithstanding, it is not trivial to describe egocentric sport videos using well-defined activities. For this reason, summarizing egocentric sport videos based on human-object interaction might fail to produce meaningful results. In this paper, we propose an unsupervised method for summarizing egocentric videos by identifying the key-frames of the video. Our method utilizes both appearance and motion information and it automatically finds the number of the key-frames. Our blind user study on the new dataset collected from YouTube shows that in 93:5% cases, the users choose the proposed method as their first video summary choice. In addition, our method is within the top 2 choices of the users in 99% of studies.

Claims-Based Authentication for a Web-Based Enterprise

DTIC Science & Technology

2013-07-01

authority must use known and registered (or in specific cases defined ) certificate revocation and currency-checking software . B. Translation of...Machines and services are issued software certificates that contain the public key with the private key generated and remaining in hardware...publicly available) information. A hardware token that contains the certificate is preferred to software -only certificates. For enterprise users

Participation under the Spotlight: Defining Future Directions. Key Players Workshop, November 2007. Report and Action Plan

ERIC Educational Resources Information Center

Cleaver, Elizabeth; Kerr, David

2007-01-01

There is an increasing emphasis on seeking and using the views of children and young people in research, evaluation and consultation. This question was at the centre of a day-long event of presentations and workshops organized by the National Foundation for Education Research in November 2007. Key objectives for the workshop included. (1) Review…

Defining life: connecting robotics and chemistry.

PubMed

Brack, André; Troublé, Michel

2010-04-01

Life is commonly referred as open systems driven by organic chemistry capable to self reproduce and to evolve. The notion of life has also been extended to non chemical systems such as robots. The key characteristics of living systems, i.e. autonomy, self-replication, self-reproduction, self-organization, self-aggregation, autocatalysis, as defined in chemistry and in robotics, are compared in a dialogue between a chemist and a robotitian.

The Nature Conservancy's Gulf Wings Project – A Case Study in Conservation Planning for Migratory Birds

Treesearch

Charles Duncan; Becky Abel; Danny Kwan; David Mehlman

2005-01-01

The Nature Conservancy has adopted a framework for mission success called Conservation by Design. We plan at the ecoregional level to define conservation targets and the portfolio of sites needed to protect them. We consider threats and strategies for abating them at these key sites, and we define measures of success to hold ourselves accountable. Migratory birds...

Recent Trends in General Education Design, Learning Outcomes, and Teaching Approaches. Key Findings from a Survey among Administrators at AAC&U Member Institutions

ERIC Educational Resources Information Center

Association of American Colleges and Universities, 2016

2016-01-01

This report summarizes key findings from a national survey among chief academic officers at Association of American Colleges and Universities (AAC&U) member institutions and explores how institutions are defining common learning outcomes, trends related to general education design and the use of emerging, evidence-based teach­ing and learning…

Towards a new definition of return-to-work outcomes in common mental disorders from a multi-stakeholder perspective.

PubMed

Hees, Hiske L; Nieuwenhuijsen, Karen; Koeter, Maarten W J; Bültmann, Ute; Schene, Aart H

2012-01-01

To examine the perspectives of key stakeholders involved in the return-to-work (RTW) process regarding the definition of successful RTW outcome after sickness absence related to common mental disorders (CMD's). A mixed-method design was used: First, we used qualitative methods (focus groups, interviews) to identify a broad range of criteria important for the definition of successful RTW (N = 57). Criteria were grouped into content-related clusters. Second, we used a quantitative approach (online questionnaire) to identify, among a larger stakeholder sample (N = 178), the clusters and criteria most important for successful RTW. A total of 11 clusters, consisting of 52 unique criteria, were identified. In defining successful RTW, supervisors and occupational physicians regarded "Sustainability" and "At-work functioning" most important, while employees regarded "Sustainability," "Job satisfaction," "Work-home balance," and "Mental Functioning" most important. Despite agreement on the importance of certain criteria, considerable differences among stakeholders were observed. Key stakeholders vary in the aspects and criteria they regard as important when defining successful RTW after CMD-related sickness absence. Current definitions of RTW outcomes used in scientific research may not accurately reflect these key stakeholder perspectives. Future studies should be more aware of the perspective from which they aim to evaluate the effectiveness of a RTW intervention, and define their RTW outcomes accordingly.

Defining competency-based evaluation objectives in family medicine

PubMed Central

Lawrence, Kathrine; Allen, Tim; Brailovsky, Carlos; Crichton, Tom; Bethune, Cheri; Donoff, Michel; Laughlin, Tom; Wetmore, Stephen; Carpentier, Marie-Pierre; Visser, Shaun

2011-01-01

Abstract Objective To develop key features for priority topics previously identified by the College of Family Physicians of Canada that, together with skill dimensions and phases of the clinical encounter, broadly describe competence in family medicine. Design Modified nominal group methodology, which was used to develop key features for each priority topic through an iterative process. Setting The College of Family Physicians of Canada. Participants An expert group of 7 family physicians and 1 educational consultant, all of whom had experience in assessing competence in family medicine. Group members represented the Canadian family medicine context with respect to region, sex, language, community type, and experience. Methods The group used a modified Delphi process to derive a detailed operational definition of competence, using multiple iterations until consensus was achieved for the items under discussion. The group met 3 to 4 times a year from 2000 to 2007. Main findings The group analyzed 99 topics and generated 773 key features. There were 2 to 20 (average 7.8) key features per topic; 63% of the key features focused on the diagnostic phase of the clinical encounter. Conclusion This project expands previous descriptions of the process of generating key features for assessment, and removes this process from the context of written examinations. A key-features analysis of topics focuses on higher-order cognitive processes of clinical competence. The project did not define all the skill dimensions of competence to the same degree, but it clearly identified those requiring further definition. This work generates part of a discipline-specific, competency-based definition of family medicine for assessment purposes. It limits the domain for assessment purposes, which is an advantage for the teaching and assessment of learners. A validation study on the content of this work would ensure that it truly reflects competence in family medicine. PMID:21998245

A practical guide to assessing clinical decision-making skills using the key features approach.

PubMed

Farmer, Elizabeth A; Page, Gordon

2005-12-01

This paper in the series on professional assessment provides a practical guide to writing key features problems (KFPs). Key features problems test clinical decision-making skills in written or computer-based formats. They are based on the concept of critical steps or 'key features' in decision making and represent an advance on the older, less reliable patient management problem (PMP) formats. The practical steps in writing these problems are discussed and illustrated by examples. Steps include assembling problem-writing groups, selecting a suitable clinical scenario or problem and defining its key features, writing the questions, selecting question response formats, preparing scoring keys, reviewing item quality and item banking. The KFP format provides educators with a flexible approach to testing clinical decision-making skills with demonstrated validity and reliability when constructed according to the guidelines provided.

Medicine in the 21st century: recommended essential geriatrics competencies for internal medicine and family medicine residents.

PubMed

Williams, Brent C; Warshaw, Gregg; Fabiny, Anne Rebecca; Lundebjerg Mpa, Nancy; Medina-Walpole, Annette; Sauvigne, Karen; Schwartzberg, Joanne G; Leipzig, Rosanne M

2010-09-01

Physician workforce projections by the Institute of Medicine require enhanced training in geriatrics for all primary care and subspecialty physicians. Defining essential geriatrics competencies for internal medicine and family medicine residents would improve training for primary care and subspecialty physicians. The objectives of this study were to (1) define essential geriatrics competencies common to internal medicine and family medicine residents that build on established national geriatrics competencies for medical students, are feasible within current residency programs, are assessable, and address the Accreditation Council for Graduate Medical Education competencies; and (2) involve key stakeholder organizations in their development and implementation. Initial candidate competencies were defined through small group meetings and a survey of more than 100 experts, followed by detailed item review by 26 program directors and residency clinical educators from key professional organizations. Throughout, an 8-member working group made revisions to maintain consistency and compatibility among the competencies. Support and participation by key stakeholder organizations were secured throughout the project. The process identified 26 competencies in 7 domains: Medication Management; Cognitive, Affective, and Behavioral Health; Complex or Chronic Illness(es) in Older Adults; Palliative and End-of-Life Care; Hospital Patient Safety; Transitions of Care; and Ambulatory Care. The competencies map directly onto the medical student geriatric competencies and the 6 Accreditation Council for Graduate Medical Education Competencies. Through a consensus-building process that included leadership and members of key stakeholder organizations, a concise set of essential geriatrics competencies for internal medicine and family medicine residencies has been developed. These competencies are well aligned with concerns for residency training raised in a recent Medicare Payment Advisory Commission report to Congress. Work is underway through stakeholder organizations to disseminate and assess the competencies among internal medicine and family medicine residency programs.

Development of an optimised key worker framework for people with dementia, their family and caring unit living in the community.

PubMed

Renehan, Emma; Goeman, Dianne; Koch, Susan

2017-07-20

In Australia, dementia is a national health priority. With the rising number of people living with dementia and shortage of formal and informal carers predicted in the near future, developing approaches to coordinating services in quality-focused ways is considered an urgent priority. Key worker support models are one approach that have been used to assist people living with dementia and their caring unit coordinate services and navigate service systems; however, there is limited literature outlining comprehensive frameworks for the implementation of community dementia key worker roles in practice. In this paper an optimised key worker framework for people with dementia, their family and caring unit living in the community is developed and presented. A number of processes were undertaken to inform the development of a co-designed optimised key worker framework: an expert working and reference group; a systematic review of the literature; and a qualitative evaluation of 14 dementia key worker models operating in Australia involving 14 interviews with organisation managers, 19 with key workers and 15 with people living with dementia and/or their caring unit. Data from the systematic review and evaluation of dementia key worker models were analysed by the researchers and the expert working and reference group using a constant comparative approach to define the essential components of the optimised framework. The developed framework consisted of four main components: overarching philosophies; organisational context; role definition; and key worker competencies. A number of more clearly defined sub-themes sat under each component. Reflected in the framework is the complexity of the dementia journey and the difficulty in trying to develop a 'one size fits all' approach. This co-designed study led to the development of an evidence based framework which outlines a comprehensive synthesis of components viewed as being essential to the implementation of a dementia key worker model of care in the community. The framework was informed and endorsed by people living with dementia and their caring unit, key workers, managers, Australian industry experts, policy makers and researchers. An evaluation of its effectiveness and relevance for practice within the dementia care space is required.

Chapter 3. Coordination and collaboration with interface units. Recommendations and standard operating procedures for intensive care unit and hospital preparations for an influenza epidemic or mass disaster.

PubMed

Joynt, Gavin M; Loo, Shi; Taylor, Bruce L; Margalit, Gila; Christian, Michael D; Sandrock, Christian; Danis, Marion; Leoniv, Yuval; Sprung, Charles L

2010-04-01

To provide recommendations and standard operating procedures (SOPs) for intensive care unit (ICU) and hospital preparations for an influenza pandemic or mass disaster with a specific focus on enhancing coordination and collaboration between the ICU and other key stakeholders. Based on a literature review and expert opinion, a Delphi process was used to define the essential topics including coordination and collaboration. Key recommendations include: (1) establish an Incident Management System with Emergency Executive Control Groups at facility, local, regional/state or national levels to exercise authority and direction over resource use and communications; (2) develop a system of communication, coordination and collaboration between the ICU and key interface departments within the hospital; (3) identify key functions or processes requiring coordination and collaboration, the most important of these being manpower and resources utilization (surge capacity) and re-allocation of personnel, equipment and physical space; (4) develop processes to allow smooth inter-departmental patient transfers; (5) creating systems and guidelines is not sufficient, it is important to: (a) identify the roles and responsibilities of key individuals necessary for the implementation of the guidelines; (b) ensure that these individuals are adequately trained and prepared to perform their roles; (c) ensure adequate equipment to allow key coordination and collaboration activities; (d) ensure an adequate physical environment to allow staff to properly implement guidelines; (6) trigger events for determining a crisis should be defined. Judicious planning and adoption of protocols for coordination and collaboration with interface units are necessary to optimize outcomes during a pandemic.

Chapter 3. Coordination and collaboration with interface units

PubMed Central

Joynt, Gavin M.; Loo, Shi; Taylor, Bruce L.; Margalit, Gila; Christian, Michael D.; Sandrock, Christian; Danis, Marion; Leoniv, Yuval

2016-01-01

Purpose To provide recommendations and standard operating procedures (SOPs) for intensive care unit (ICU) and hospital preparations for an influenza pandemic or mass disaster with a specific focus on enhancing coordination and collaboration between the ICU and other key stakeholders. Methods Based on a literature review and expert opinion, a Delphi process was used to define the essential topics including coordination and collaboration. Results Key recommendations include: (1) establish an Incident Management System with Emergency Executive Control Groups at facility, local, regional/state or national levels to exercise authority and direction over resource use and communications; (2) develop a system of communication, coordination and collaboration between the ICU and key interface departments within the hospital; (3) identify key functions or processes requiring coordination and collaboration, the most important of these being manpower and resources utilization (surge capacity) and re-allocation of personnel, equipment and physical space; (4) develop processes to allow smooth inter-departmental patient transfers; (5) creating systems and guidelines is not sufficient, it is important to: (a) identify the roles and responsibilities of key individuals necessary for the implementation of the guidelines; (b) ensure that these individuals are adequately trained and prepared to perform their roles; (c) ensure adequate equipment to allow key coordination and collaboration activities; (d) ensure an adequate physical environment to allow staff to properly implement guidelines; (6) trigger events for determining a crisis should be defined. Conclusions Judicious planning and adoption of protocols for coordination and collaboration with interface units are necessary to optimize outcomes during a pandemic. PMID:20213418

Defining and Measuring Cognitive-Entropy and Cognitive Self-Synchronization

DTIC Science & Technology

2011-06-01

16th ICCRTS: “Collective C2 in Multinational Civil-Military Operations” Defining and Measuring Cognitive-Entropy and Cognitive Self- Synchronization ...shared awareness and enabling self- synchronization across the range of participating entities (Alberts and Hayes 2009, pp.106). We consider the...aspect of self- synchronization (Alberts and Hayes, 2006) a key one in the context of modern operations and in performing C2 assessments. Based on (Manso

An absolute measure for a key currency

NASA Astrophysics Data System (ADS)

Oya, Shunsuke; Aihara, Kazuyuki; Hirata, Yoshito

It is generally considered that the US dollar and the euro are the key currencies in the world and in Europe, respectively. However, there is no absolute general measure for a key currency. Here, we investigate the 24-hour periodicity of foreign exchange markets using a recurrence plot, and define an absolute measure for a key currency based on the strength of the periodicity. Moreover, we analyze the time evolution of this measure. The results show that the credibility of the US dollar has not decreased significantly since the Lehman shock, when the Lehman Brothers bankrupted and influenced the economic markets, and has increased even relatively better than that of the euro and that of the Japanese yen.

CrossTalk: The Journal of Defense Software Engineering. Volume 19, Number 7

DTIC Science & Technology

2006-07-01

public key certificates and cryptographic keys for crypto - graphic devices. In an environment where enterprise protection relies on an array of IA-enabled...allowing for greater accuracy, currency , and relevance of the information con- tained in the satellite communications data- base will be evaluated...JWPO). The purpose of the JWPO is to define, develop, validate, and evolve the JTRS SCA; acquire wave- form software applications; acquire Crypto

Sexual Assault Prevention and Response Website Analysis

DTIC Science & Technology

2014-09-01

IRR inter-rater reliability KPI key performance indicator N17 U.S Navy 21st Century Sailor Office NASASV National Association of Services Against...determine if progress is being made to achieve the desired goal; this is typically done by establishing key performance indicators 22 ( KPI ). After...defining the KPIs , organizations must prioritize the potential solutions and devise a plan for making small incremental changes to accurately assess the

DOD Financial Management: Effect of Continuing Weaknesses on Management and Operations and Status of Key Challenges

DTIC Science & Technology

2014-05-13

the information needed to effectively (1) manage its assets, (2) assess program performance and make budget decisions , (3) make cost- effective ... decision making, including the information needed to effectively (1) manage its assets, (2) assess program performance and make budget decisions , (3...incorporating key elements of a comprehensive management approach , such as a complete analysis of the return on investment, quantitatively -defined goals

Optimizing Catalysts for Solar Fuel Production: Spectroscopic Characterization of the Key Reaction Intermediates

DTIC Science & Technology

2013-04-01

which freezes ions into well defined structures and coats them with an inert layer of weakly bound adducts. These cold aggregates were then...evaporation of the cryogenic solvent. Instrument development. Cryogenic ion processing. Cold ion spectroscopy. Trapped reaction intermediates U U U...spectrometer. The key advance incorporated into this instrument is the introduction of a cryogenic (10K) ion processing stage, where ions can be frozen

Performance Analysis and Optimization of the Winnow Secret Key Reconciliation Protocol

DTIC Science & Technology

2011-06-01

use in a quantum key system can be defined in two ways :  The number of messages passed between Alice and Bob  The...classical and quantum environment. Post- quantum cryptography , which is generally used to describe classical quantum -resilient protocols, includes...composed of a one- way quantum channel and a two - way classical channel. Owing to the physics of the channel, the quantum channel is subject to

BIOSURFACES AND BIOAVAILABILITY: A NANOSCALE OVERVIEW

EPA Science Inventory

Environmentally, contaminant bioavailability is a key parameter in determining exposure assessment and ultimately risk assessment/risk management. Defining bioavailability requires knowledge of the contaminant spatial/temporal disposition and transportability and the thermodyna...

Toward a general theory of conical intersections in systems of identical nuclei

NASA Astrophysics Data System (ADS)

Keating, Sean P.; Mead, C. Alden

1987-02-01

It has been shown previously that the Herzberg-Longuet-Higgins sign change produced in Born-Oppenheimer electronic wave functions when the nuclei traverse a closed path around a conical intersection has implications for the symmetry of wave functions under permutations of identical nuclei. For systems of three or four identical nuclei, there are special features present which have facilitated the detailed analysis. The present paper reports progress toward a general theory for systems of n nuclei. For n=3 or 4, the two key functions which locate conical intersections and define compensating phase factors can conveniently be defined so as to transform under permutations according to a two-dimensional irreducible representation of the permutation group. Since such representations do not exist for n>4, we have chosen to develop a formalism in terms of lab-fixed electronic basis functions, and we show how to define the two key functions in principle. The functions so defined both turn out to be totally symmetric under permutations. We show how they can be used to define compensating phase factors so that all modified electronic wave functions are either totally symmetric or totally antisymmetric under permutations. A detailed analysis is made to cyclic permutations in the neighborhood of Dnh symmetry, which can be extended by continuity arguments to more general configurations, and criteria are obtained for sign changes. There is a qualitative discussion of the treatment of more general permutations.

A risk-based auditing process for pharmaceutical manufacturers.

PubMed

Vargo, Susan; Dana, Bob; Rangavajhula, Vijaya; Rönninger, Stephan

2014-01-01

The purpose of this article is to share ideas on developing a risk-based model for the scheduling of audits (both internal and external). Audits are a key element of a manufacturer's quality system and provide an independent means of evaluating the manufacturer's or the supplier/vendor's compliance status. Suggestions for risk-based scheduling approaches are discussed in the article. Pharmaceutical manufacturers are required to establish and implement a quality system. The quality system is an organizational structure defining responsibilities, procedures, processes, and resources that the manufacturer has established to ensure quality throughout the manufacturing process. Audits are a component of the manufacturer's quality system and provide a systematic and an independent means of evaluating the manufacturer's overall quality system and compliance status. Audits are performed at defined intervals for a specified duration. The intention of the audit process is to focus on key areas within the quality system and may not cover all relevant areas during each audit. In this article, the authors provide suggestions for risk-based scheduling approaches to aid pharmaceutical manufacturers in identifying the key focus areas for an audit.

Encryption key distribution via chaos synchronization

NASA Astrophysics Data System (ADS)

Keuninckx, Lars; Soriano, Miguel C.; Fischer, Ingo; Mirasso, Claudio R.; Nguimdo, Romain M.; van der Sande, Guy

2017-02-01

We present a novel encryption scheme, wherein an encryption key is generated by two distant complex nonlinear units, forced into synchronization by a chaotic driver. The concept is sufficiently generic to be implemented on either photonic, optoelectronic or electronic platforms. The method for generating the key bitstream from the chaotic signals is reconfigurable. Although derived from a deterministic process, the obtained bit series fulfill the randomness conditions as defined by the National Institute of Standards test suite. We demonstrate the feasibility of our concept on an electronic delay oscillator circuit and test the robustness against attacks using a state-of-the-art system identification method.

What's D&T For? Gathering and Comparing the Values of Design and Technology Academics and Trainee Teachers

ERIC Educational Resources Information Center

Hardy, Alison

2015-01-01

Some who read and research about Design & Technology (D&T) would say that the concept of value is key to understanding and defining D&T. Closer inspection reveals though that there are two ways in which values are defined in D&T: how values are taught and learnt about in D&T to use them to make judgments in D&T lessons, and…

Optical keyboard

DOE Office of Scientific and Technical Information (OSTI.GOV)

Veligdan, James T.; Feichtner, John D.; Phillips, Thomas E.

2001-01-01

An optical keyboard includes an optical panel having optical waveguides stacked together. First ends of the waveguides define an inlet face, and opposite ends thereof define a screen. A projector transmits a light beam outbound through the waveguides for display on the screen as a keyboard image. A light sensor is optically aligned with the inlet face for sensing an inbound light beam channeled through the waveguides from the screen upon covering one key of the keyboard image.

Greenroads : a sustainability performance metric for roadway design and construction.

DOT National Transportation Integrated Search

2009-11-01

Greenroads is a performance metric for quantifying sustainable practices associated with roadway design and construction. Sustainability is defined as having seven key components: ecology, equity, economy, extent, expectations, experience and exposur...

Using Dietary Supplements Wisely

MedlinePlus

... T U V W X Y Z Using Dietary Supplements Wisely Share: On This Page Key Points About ... will help ensure coordinated and safe care. About Dietary Supplements Dietary supplements were defined in a law passed ...

Space Tug systems study (storable). Volume 3: Executive summary

NASA Technical Reports Server (NTRS)

1974-01-01

Space tug program options that consider key issues and mission requirements are assessed, component and subsystem candidates are evaluated, and tug configurations synthesized. Three tug program options are defined and evaluated.

Software reconfigurable processor technologies: the key to long-life infrastructure for future space missions

NASA Technical Reports Server (NTRS)

Srinivasan, J.; Farrington, A.; Gray, A.

2001-01-01

They present an overview of long-life reconfigurable processor technologies and of a specific architecture for implementing a software reconfigurable (software-defined) network processor for space applications.

40 CFR 355.61 - How are key words in this part defined?

Code of Federal Regulations, 2012 CFR

2012-07-01

... waste when mixed or commingled with bedding, compost, feed, soil and other typical materials found with... aqueous or organic solutions, slurries, viscous solutions, suspensions, emulsions, or pastes. State means...

40 CFR 355.61 - How are key words in this part defined?

Code of Federal Regulations, 2013 CFR

2013-07-01

... waste when mixed or commingled with bedding, compost, feed, soil and other typical materials found with... aqueous or organic solutions, slurries, viscous solutions, suspensions, emulsions, or pastes. State means...

A Proposed Curriculum Model for Geriatric Optometry.

ERIC Educational Resources Information Center

Rosenbloom, Albert A.

1985-01-01

A model for a geriatric optometry curriculum that defines key content areas and addresses the values essential for effective practice and basic therapeutic modalities used in treatment regimens with older adults is outlined. (MSE)

Priority directions of the improvement of energy management at the enterprise

NASA Astrophysics Data System (ADS)

Dyakova, Galina; Izmaylova, Svetlana; Mottaeva, Angela; Karanina, Elena

2017-10-01

The relevance of article is caused by the fact that at the industrial enterprises pay little attention to the matters of energy saving or to the management of energy efficiency. The authors of the article defined that the potential of the increase in energy efficiency as well as the improvement of quality of strategic management at the enterprise, is connected with investment into the human capital. For the improvement of system of energy management, the key indicators of energy efficiency at the individual level are defined, the algorithm of the development of key indicators by means of which the energy efficiency of the human capital will be measured is developed, actions for support to the developed transitional strategy of power management are offered, positive results of formation of the human capital directed to increase in energy efficiency are designated.

Astrophysics of Reference Frame Tie Objects

NASA Technical Reports Server (NTRS)

Johnston, Kenneth J.; Boboltz, David; Fey, Alan Lee; Gaume, Ralph A.; Zacharias, Norbert

2004-01-01

The Astrophysics of Reference Frame Tie Objects Key Science program will investigate the underlying physics of SIM grid objects. Extragalactic objects in the SIM grid will be used to tie the SIM reference frame to the quasi-inertial reference frame defined by extragalactic objects and to remove any residual frame rotation with respect to the extragalactic frame. The current realization of the extragalactic frame is the International Celestial Reference Frame (ICRF). The ICRF is defined by the radio positions of 212 extragalactic objects and is the IAU sanctioned fundamental astronomical reference frame. This key project will advance our knowledge of the physics of the objects which will make up the SIM grid, such as quasars and chromospherically active stars, and relates directly to the stability of the SIM reference frame. The following questions concerning the physics of reference frame tie objects will be investigated.

Orbital transfer vehicle concept definition and system analysis study, 1986. Volume 9: Study extension results

NASA Technical Reports Server (NTRS)

Kofal, Allen E.

1987-01-01

The purpose of this extension to the OTV Concept Definition and Systems Analysis Study was to improve the definition of the OTV Program that will be most beneficial to the nation in the 1995 to 2010 timeframe. The implications of the defined mission and defined launch vehicle are investigated. The key mission requirements identified for the Space Transportation Architecture Study (STAS) were established and reflect a need for early capability and more ambitious capability growth. The key technical objectives and related issues addressed are summarized. The analyses of selected areas including aerobrake design, proximity operations, and the balance of EVA and IVA operations used in the support of the OTV at the space-base were enhanced. Sensitivity studies were conducted to establish how the OTV program should be tailored to meet changing circumstances.

The Functional Impact of the Intestinal Microbiome on Mucosal Immunity and Systemic Autoimmunity

PubMed Central

Longman, Randy S.; Littman, Dan R.

2016-01-01

Purpose of Review This review will highlight recent advances functionally linking the gut microbiome with mucosal and systemic immune cell activation potentially underlying autoimmunity. Recent Findings Dynamic interactions between the gut microbiome and environmental cues (including diet and medicines) shape the effector potential of the microbial organ. Key bacteria and viruses have emerged, that, in defined microenvironments, play a critical role in regulating effector lymphocyte functions. The coordinated interactions between these different microbial kingdoms—including bacteria, helminths, and viruses (termed transkingdom interactions)—play a critical role in shaping immunity. Emerging strategies to identify immunologically-relevant microbes with the potential to regulate immune cell functions both at mucosal sites and systemically will likely define key diagnostic and therapeutic targets. Summary The microbiome constitutes a critical microbial organ with coordinated interactions that shape host immunity. PMID:26002030

Towards a New Definition of Return-to-Work Outcomes in Common Mental Disorders from a Multi-Stakeholder Perspective

PubMed Central

Hees, Hiske L.; Nieuwenhuijsen, Karen; Koeter, Maarten W. J.; Bültmann, Ute; Schene, Aart H.

2012-01-01

Objectives To examine the perspectives of key stakeholders involved in the return-to-work (RTW) process regarding the definition of successful RTW outcome after sickness absence related to common mental disorders (CMD’s). Methods A mixed-method design was used: First, we used qualitative methods (focus groups, interviews) to identify a broad range of criteria important for the definition of successful RTW (N = 57). Criteria were grouped into content-related clusters. Second, we used a quantitative approach (online questionnaire) to identify, among a larger stakeholder sample (N = 178), the clusters and criteria most important for successful RTW. Results A total of 11 clusters, consisting of 52 unique criteria, were identified. In defining successful RTW, supervisors and occupational physicians regarded “Sustainability” and “At-work functioning” most important, while employees regarded “Sustainability,” “Job satisfaction,” “Work-home balance,” and “Mental Functioning” most important. Despite agreement on the importance of certain criteria, considerable differences among stakeholders were observed. Conclusions Key stakeholders vary in the aspects and criteria they regard as important when defining successful RTW after CMD-related sickness absence. Current definitions of RTW outcomes used in scientific research may not accurately reflect these key stakeholder perspectives. Future studies should be more aware of the perspective from which they aim to evaluate the effectiveness of a RTW intervention, and define their RTW outcomes accordingly. PMID:22768180

NASA Electronic Library System (NELS) database schema, version 1.2

NASA Technical Reports Server (NTRS)

Melebeck, Clovis J.

1991-01-01

The database tables used by NELS version 1.2 are discussed. To provide the current functional capability offered by NELS, nineteen tables were created with ORACLE. Each table lists the ORACLE table name and provides a brief description of the tables intended use or function. The following sections cover four basic categories of tables: NELS object classes, NELS collections, NELS objects, and NELS supplemental tables. Also included in each section is a definition and/or relationship of each field to other fields or tables. The primary key(s) for each table is indicated with a single asterisk (*), while foreign keys are indicated with double asterisks (**). The primary key(s) indicate the key(s) which uniquely identifies a record for that table. The foreign key(s) is used to identify additional information in other table(s) for that record. The two appendices are the command which is used to construct the ORACLE tables for NELS. Appendix A contains the commands which create the tables which are defined in the following sections. Appendix B contains the commands which build the indices for these tables.

Transactional Distance as a Predictor of Perceived Learner Satisfaction in Distance Learning Courses: A Case Study of Bachelor of Education Arts Program, University of Nairobi, Kenya

ERIC Educational Resources Information Center

Mbwesa, Joyce Kanini

2014-01-01

There is a long history of study and recognition of the critical role of interaction in supporting and even defining distance education. Interaction has been identified as key to the success of distance learning. It is key in fostering, supporting and engaging in the learning process. Moore (1989) posits that the physical distance that exists in…

Executing on Integration: The Key to Success in Mergers and Acquisitions.

PubMed

Bradley, Carol

2016-01-01

Health care mergers and acquisitions require a clearly stated vision and exquisite planning of integration activities to provide the best possible conditions for a successful transaction. During the due diligence process, key steps can be taken to create a shared vision and a plan to inspire confidence and build enthusiasm for all stakeholders. Integration planning should include a defined structure, roles and responsibilities, as well as a method for evaluation.

DNA reactivity as a mode of action and its relevance to cancer risk assessment.

PubMed

Preston, R Julian

2013-02-01

The ability of a chemical to induce mutations has long been a driver in the cancer risk assessment process. The default strategy has been that mutagenic chemicals demonstrate linear cancer dose responses, especially at low exposure levels. In the absence of additional confounding information, this is a reasonable approach, because risk assessment is appropriately considered as being protective of human health. The concept of mode of action has allowed for an opportunity to move off this default position; mutagenicity is now not considered as the driver but rather the mode of action is. In a more precise way, it is the set of key events that define a mode of action that is fundamental in defining the shape of a cancer dose response. A key event is an informative bioindicator of the cancer response and as such should be predictive of the tumor response, at least in a qualitative way. A clear example of the use of key events in cancer risk assessment is for DNA reactive chemicals. A series of such key events is initiated by the production of DNA damage in target cells from direct interaction of the chemical with DNA leading to the production of mutations by misreplication that results in enhanced cell replication. This enhanced cell replication eventually leads to the development of preneoplastic cells and ultimately overt neoplasms. The response of each of these key events to dose of the chemical can inform the cancer dose-response curve shape. Thus, the dose-response curve for any DNA-reactive chemical can be predicted from knowledge of its mode of action and the behavior of the induced key events.

FHWA LTBP Bridge Performance Primer

DOT National Transportation Integrated Search

2014-02-01

This TechBrief defines bridge performance and discusses the importance of measuring performance and current practices for doing so. It identifies key issues to improving performance measures and the role the Long-Term Bridge Performance (LTBP) Progra...

The Seven Principles of Sustainable Leadership

ERIC Educational Resources Information Center

Hargreaves, Andy; Fink, Dean

2004-01-01

A study conducted by Spencer Foundation examining eight US and Canadian schools found that the key force leading to meaningful, long-term change in educational institution is leadership sustainability. The seven principles defining sustainable leadership are discussed.

Use of Log-Linear Models in Classification Problems.

DTIC Science & Technology

1981-12-01

polynomials. The second example involves infant hypoxic trauma, and many cells are empty. The existence conditions are used to find a model for which esti...mates of cell frequencies exist and are in good agreement with the ob- served data. Key Words: Classification problem, log-difference models, minimum 8...variates define k states, which are labeled consecutively. Thus, while MB define cells in their tables by an I-vector Z, we simply take Z to be a

A Statistical Analysis of IrisCode and Its Security Implications.

PubMed

Kong, Adams Wai-Kin

2015-03-01

IrisCode has been used to gather iris data for 430 million people. Because of the huge impact of IrisCode, it is vital that it is completely understood. This paper first studies the relationship between bit probabilities and a mean of iris images (The mean of iris images is defined as the average of independent iris images.) and then uses the Chi-square statistic, the correlation coefficient and a resampling algorithm to detect statistical dependence between bits. The results show that the statistical dependence forms a graph with a sparse and structural adjacency matrix. A comparison of this graph with a graph whose edges are defined by the inner product of the Gabor filters that produce IrisCodes shows that partial statistical dependence is induced by the filters and propagates through the graph. Using this statistical information, the security risk associated with two patented template protection schemes that have been deployed in commercial systems for producing application-specific IrisCodes is analyzed. To retain high identification speed, they use the same key to lock all IrisCodes in a database. The belief has been that if the key is not compromised, the IrisCodes are secure. This study shows that even without the key, application-specific IrisCodes can be unlocked and that the key can be obtained through the statistical dependence detected.

Encryption key distribution via chaos synchronization

PubMed Central

Keuninckx, Lars; Soriano, Miguel C.; Fischer, Ingo; Mirasso, Claudio R.; Nguimdo, Romain M.; Van der Sande, Guy

2017-01-01

We present a novel encryption scheme, wherein an encryption key is generated by two distant complex nonlinear units, forced into synchronization by a chaotic driver. The concept is sufficiently generic to be implemented on either photonic, optoelectronic or electronic platforms. The method for generating the key bitstream from the chaotic signals is reconfigurable. Although derived from a deterministic process, the obtained bit series fulfill the randomness conditions as defined by the National Institute of Standards test suite. We demonstrate the feasibility of our concept on an electronic delay oscillator circuit and test the robustness against attacks using a state-of-the-art system identification method. PMID:28233876

25 CFR 292.2 - How are key terms defined in this part?

Code of Federal Regulations, 2010 CFR

2010-04-01

... or a public road or right-of-way and includes parcels that touch at a point. Former reservation means... establish that its governmental functions, infrastructure or services will be directly, immediately and...

25 CFR 292.2 - How are key terms defined in this part?

Code of Federal Regulations, 2011 CFR

2011-04-01

... or a public road or right-of-way and includes parcels that touch at a point. Former reservation means... establish that its governmental functions, infrastructure or services will be directly, immediately and...

Around and beyond 53BP1 Nuclear Bodies.

PubMed

Fernandez-Vidal, Anne; Vignard, Julien; Mirey, Gladys

2017-12-05

Within the nucleus, sub-nuclear domains define territories where specific functions occur. Nuclear bodies (NBs) are dynamic structures that concentrate nuclear factors and that can be observed microscopically. Recently, NBs containing the p53 binding protein 1 (53BP1), a key component of the DNA damage response, were defined. Interestingly, 53BP1 NBs are visualized during G1 phase, in daughter cells, while DNA damage was generated in mother cells and not properly processed. Unlike most NBs involved in transcriptional processes, replication has proven to be key for 53BP1 NBs, with replication stress leading to the formation of these large chromatin domains in daughter cells. In this review, we expose the composition and organization of 53BP1 NBs and focus on recent findings regarding their regulation and dynamics. We then concentrate on the importance of the replication stress, examine the relation of 53BP1 NBs with DNA damage and discuss their dysfunction.

A Blueprint for Innovation to Achieve Health System Transformation.

PubMed

Snowdon, Anne W

2017-01-01

Global health systems are challenged by escalating costs and growing demands for care created by the demands of aging populations and rising rates of chronic illness which place unsustainable pressure on health systems to meet population health needs. To overcome these challenges, transformational change is needed to strengthen health system performance and sustainability. Innovation is widely viewed as the strategy to drive transformational change in health systems; yet to date, innovation has lacked a clearly defined focus or agenda to achieve transformation. An actionable innovation agenda is needed to achieve transformational change for health systems. The key conditions for success as an innovation strategy are examined, including clearly defined innovation objectives, key milestones, and actionable steps every system stakeholder must pursue in order to guide the innovation agenda and ultimately accelerate the transformational changes needed for a sustainable healthcare system that delivers value to populations.

Earth Observing System/Meteorological Satellite (EOS/METSAT). Advanced Microwave Sounding Unit-A (AMSU-A) Contamination Control Plan

NASA Technical Reports Server (NTRS)

Fay, M.

1998-01-01

This Contamination Control Plan is submitted in response the Contract Document requirements List (CDRL) 007 under contract NAS5-32314 for the Earth Observing System (EOS) Advanced Microwave Sounding Unit A (AMSU-A). In response to the CDRL instructions, this document defines the level of cleanliness and methods/procedures to be followed to achieve adequate cleanliness/contamination control, and defines the required approach to maintain cleanliness/contamination control through shipping, observatory integration, test, and flight. This plan is also applicable to the Meteorological Satellite (METSAT) except where requirements are identified as EOS-specific. This plan is based on two key factors: a. The EOS/METSAT AMSU-A Instruments are not highly contamination sensitive. b. Potential contamination of other EOS Instruments is a key concern as addressed in Section 9/0 of the Performance Assurance Requirements for EOS/METSAT Integrated Programs AMSU-A Instrument (MR) (NASA Specification S-480-79).

Approaches to defining reference regimes for river restoration planning

NASA Astrophysics Data System (ADS)

Beechie, T. J.

2014-12-01

Reference conditions or reference regimes can be defined using three general approaches, historical analysis, contemporary reference sites, and theoretical or empirical models. For large features (e.g., floodplain channels and ponds) historical data and maps are generally reliable. For smaller features (e.g., pools and riffles in small tributaries), field data from contemporary reference sites are a reasonable surrogate for historical data. Models are generally used for features that have no historical information or present day reference sites (e.g., beaver pond habitat). Each of these approaches contributes to a watershed-wide understanding of current biophysical conditions relative to potential conditions, which helps create not only a guiding vision for restoration, but also helps quantify and locate the largest or most important restoration opportunities. Common uses of geomorphic and biological reference conditions include identifying key areas for habitat protection or restoration, and informing the choice of restoration targets. Examples of use of each of these three approaches to define reference regimes in western USA illustrate how historical information and current research highlight key restoration opportunities, focus restoration effort in areas that can produce the largest ecological benefit, and contribute to estimating restoration potential and assessing likelihood of achieving restoration goals.

The concept lens diagram: a new mechanism for presenting biochemistry content in terms of "big ideas".

PubMed

Rowland, Susan L; Smith, Christopher A; Gillam, Elizabeth M A; Wright, Tony

2011-07-01

A strong, recent movement in tertiary education is the development of conceptual, or "big idea" teaching. The emphasis in course design is now on promoting key understandings, core competencies, and an understanding of connections between different fields. In biochemistry teaching, this radical shift from the content-based tradition is being driven by the "omics" information explosion; we can no longer teach all the information we have available. Biochemistry is a core, enabling discipline for much of modern scientific research, and biochemistry teaching is in urgent need of a method for delivery of conceptual frameworks. In this project, we aimed to define the key concepts in biochemistry. We find that the key concepts we defined map well onto the core science concepts recommended by the Vision and Change project. We developed a new method to present biochemistry through the lenses of these concepts. This new method challenged the way we thought about biochemistry as teachers. It also stimulated the majority of the students to think more deeply about biochemistry and to make links between biochemistry and material in other courses. This method is applicable to the full spectrum of content usually taught in biochemistry. Copyright © 2011 Wiley Periodicals, Inc.

Do Clinical Practice Guidelines Improve Quality?

PubMed

Baldassari, Cristina M

2017-07-01

Controversy exists surrounding how to best define and assess quality in the health care setting. Clinical practice guidelines (CPGs) have been developed to improve the quality of medical care by highlighting key clinical recommendations based on recent evidence. However, data linking CPGs to improvements in outcomes in otolaryngology are lacking. Numerous barriers contribute to difficulties in translating CPGs to improvements in quality. Future initiatives are needed to improve CPG adherence and define the impact of CPG recommendations on the quality of otolaryngologic care provided to our patients.

Robotics: An Introduction to Today’s Robot and Future Trends.

DTIC Science & Technology

1983-07-01

trial applications." What qualities define a machine as a robot? The Robot Institute of Amer- ica defines a robot as follows: "A robot is a reprogrammable ...manufactures a robot with a spin- ning wrist. Second, and this is the key feature, robots are reprogrammable and hence versatile. An automatic lathe is not...robot spot-welds an automobile frame. In Figure 8, a single robot transferring a transmission case is shown, but a total of eight robots are

Vehicle performance impact on space shuttle design and concept evaluation

NASA Technical Reports Server (NTRS)

Craig, M. K.

1972-01-01

The continuing examination of widely varied space shuttle concepts makes an understanding of concept interaction with vehicle performance imperative. The estimation of vehicle performance is highly appurtenant to all aspects of shuttle design and hence performance has classically been a key indicator of overall concept desirability and potential. Vehicle performance assumes the added role of defining interactions between specific design characteristics, the sum total of which define a specific concept. Special attention is given to external tank effects.

A Parameterized Model of Amylopectin Synthesis Provides Key Insights into the Synthesis of Granular Starch

PubMed Central

Wu, Alex Chi; Morell, Matthew K.; Gilbert, Robert G.

2013-01-01

A core set of genes involved in starch synthesis has been defined by genetic studies, but the complexity of starch biosynthesis has frustrated attempts to elucidate the precise functional roles of the enzymes encoded. The chain-length distribution (CLD) of amylopectin in cereal endosperm is modeled here on the basis that the CLD is produced by concerted actions of three enzyme types: starch synthases, branching and debranching enzymes, including their respective isoforms. The model, together with fitting to experiment, provides four key insights. (1) To generate crystalline starch, defined restrictions on particular ratios of enzymatic activities apply. (2) An independent confirmation of the conclusion, previously reached solely from genetic studies, of the absolute requirement for debranching enzyme in crystalline amylopectin synthesis. (3) The model provides a mechanistic basis for understanding how successive arrays of crystalline lamellae are formed, based on the identification of two independent types of long amylopectin chains, one type remaining in the amorphous lamella, while the other propagates into, and is integral to the formation of, an adjacent crystalline lamella. (4) The model provides a means by which a small number of key parameters defining the core enzymatic activities can be derived from the amylopectin CLD, providing the basis for focusing studies on the enzymatic requirements for generating starches of a particular structure. The modeling approach provides both a new tool to accelerate efforts to understand granular starch biosynthesis and a basis for focusing efforts to manipulate starch structure and functionality using a series of testable predictions based on a robust mechanistic framework. PMID:23762422

Translating Genius: The Importance Of The Relationship Between Military Geniuses And A Key - Subordinate

DTIC Science & Technology

2014-04-01

reference to both the subjects of the research (who are all men ) and in reference to hypothetical, generic genius to key- subordinate relationships. These... men who so dominated the battlefield that they have come to be archetypes of personality and to even define entire ages of warfare. Brash, aggressive...great men , and their light burns so bright that their vision and will is single-handedly imposed upon their enemies? Or is there something more

UTM Data Working Group Demonstration 1: Final Report

NASA Technical Reports Server (NTRS)

Rios, Joseph L.; Mulfinger, Daniel G.; Smith, Irene S.; Venkatesan, Priya; Smith, David R.; Baskaran, Vijayakumar; Wang, Leo

2017-01-01

This document summarizes activities defining and executing the first demonstration of the NASA-FAA Research Transition Team (RTT) Data Exchange and Information Architecture (DEIA) working group (DWG). The demonstration focused on testing the interactions between two key components in the future UAS Traffic Management (UTM) System through a collaborative and distributed simulation of key scenarios. The summary incorporates written feedback from each of the participants in the demonstration. In addition to reporting the activities, this report also provides some insight into future steps of this working group.

Subsonic Transonic Applied Refinements By Using Key Strategies - STARBUKS In the NASA Langley Research Center National Transonic Facility

NASA Technical Reports Server (NTRS)

Paryz, Roman W.

2014-01-01

Several upgrade projects have been completed at the NASA Langley Research Center National Transonic Facility over the last 1.5 years in an effort defined as STARBUKS - Subsonic Transonic Applied Refinements By Using Key Strategies. This multi-year effort was undertaken to improve NTF's overall capabilities by addressing Accuracy and Validation, Productivity, and Reliability areas at the NTF. This presentation will give a brief synopsis of each of these efforts.

Evolving Systems and Adaptive Key Component Control

NASA Technical Reports Server (NTRS)

Frost, Susan A.; Balas, Mark J.

2009-01-01

We propose a new framework called Evolving Systems to describe the self-assembly, or autonomous assembly, of actively controlled dynamical subsystems into an Evolved System with a higher purpose. An introduction to Evolving Systems and exploration of the essential topics of the control and stability properties of Evolving Systems is provided. This chapter defines a framework for Evolving Systems, develops theory and control solutions for fundamental characteristics of Evolving Systems, and provides illustrative examples of Evolving Systems and their control with adaptive key component controllers.

Performance Evaluation of the United Nations Environment Programme Air Quality Monitoring Unit

EPA Pesticide Factsheets

This report defines the specifics of the environmental test conditions used in the evaluation (systems and conditions), data observations, summarization of key performance evaluation findings, and ease of use features concerning the UNEP pod.

The manned transportation system study - Defining human pathways into space

NASA Technical Reports Server (NTRS)

Lance, Nick; Geyer, Mark S.; Gaunce, Michael T.; Anson, H. W.; Bienhoff, D. G.; Carey, D. A.; Emmett, B. R.; Mccandless, B.; Wetzel, E. D.

1992-01-01

Substantiating data developed by a NASA-industry team (NIT) for subsequent NASA decisions on the 'right' set of manned transportation elements needed for human access to space are discussed. Attention is given to the framework for detailed definition of these manned transportation elements. Identifying and defining architecture evaluation criteria, i.e., attributes, specified the amount and type of data needed for each concept under consideration. Several architectures, each beginning with today's transportation systems, were defined using representative systems to explore future options and address specific questions currently being debated. The present solutions emphasize affordability, safety, routineness, and reliability. Key issues associated with current business practices were challenged and the impact associated with these practices quantified.

48 CFR 252.209-7002 - Disclosure of ownership or control by a foreign government.

Code of Federal Regulations, 2010 CFR

2010-10-01

... unclassified keys; (iii) Restricted Data as defined in the U.S. Atomic Energy Act of 1954, as amended; (iv... following format: Offeror's Point of Contact for Questions about Disclosure (Name and Phone Number with...

Proof of concept deployment plan.

DOT National Transportation Integrated Search

2008-02-01

The U.S. Department of Transportation (USDOT) Next Generation 9-1-1 (NG9-1-1) : Proof-of-Concept (POC) demonstration is envisioned to test key features and : functionalities of the NG9-1-1 system. The Interim POC System Design Document : defines the ...

Human factors research on performance-based navigation instrument procedures for NextGEN

DOT National Transportation Integrated Search

2012-10-14

Area navigation (RNAV) and required navigation performance (RNP) are key components of performance-based navigation (PBN). Instrument procedures that use RNAV and RNP can have more flexible and precise paths than conventional routes that are defined ...

10 CFR 1045.1 - Purpose and scope.

Code of Federal Regulations, 2011 CFR

2011-01-01

... OF ENERGY (GENERAL PROVISIONS) NUCLEAR CLASSIFICATION AND DECLASSIFICATION Program Management of the Restricted Data and Formerly Restricted Data Classification System § 1045.1 Purpose and scope. This subpart establishes responsibilities associated with this part, describes the Openness Advisory Panel, defines key...

10 CFR 1045.1 - Purpose and scope.

Code of Federal Regulations, 2010 CFR

2010-01-01

... OF ENERGY (GENERAL PROVISIONS) NUCLEAR CLASSIFICATION AND DECLASSIFICATION Program Management of the Restricted Data and Formerly Restricted Data Classification System § 1045.1 Purpose and scope. This subpart establishes responsibilities associated with this part, describes the Openness Advisory Panel, defines key...

Creating a Marketing Plan.

ERIC Educational Resources Information Center

Sevier, Robert A.

1989-01-01

A guide to developing a college marketing plan defines key marketing terms, outlines the development of a plan (including institutional analysis, market research, strategy formation and execution, and program evaluation), and provides a list of important principles with which to operate a program. (MSE)

Making Computers Smarter: A Look At the Controversial Field of Artificial Intelligence.

ERIC Educational Resources Information Center

Green, John O.

1984-01-01

Defines artificial intelligence (AI) and discusses its history; the current state of the art, research, experimentation, and practical applications; and probable future developments. Key dates in the history of AI and eight references are provided. (MBR)

Teaching for Thinking.

ERIC Educational Resources Information Center

Keefe, James W., Ed.; Walberg, Herbert J., Ed.

This volume represents a variety of current efforts to incorporate thought-provoking methods into teaching. There are three sections. "Curriculum Developments" defines key curricular terms and offers a framework and general examples of teaching tactics. In this section, Barbara Presseisen distinguishes thinking from other cognitive…

Effectiveness of workplace weight management interventions: a systematic review

USDA-ARS?s Scientific Manuscript database

Background: A systematic review was conducted of randomized trials of workplace weight management interventions, including trials with dietary, physical activity, environmental, behavioral and incentive based components. Main outcomes were defined as change in weight-related measures. Methods: Key w...

Defining Health Research for Development: The perspective of stakeholders from an international health research partnership in Ghana and Tanzania.

PubMed

Ward, Claire Leonie; Shaw, David; Anane-Sarpong, Evelyn; Sankoh, Osman; Tanner, Marcel; Elger, Bernice

2017-05-03

The study uses a qualitative empirical method to define Health Research for Development. This project explores the perspectives of stakeholders in an international health research partnership operating in Ghana and Tanzania. We conducted 52 key informant interviews with major stakeholders in an international multicenter partnership between GlaxoSmithKline (GSK, Vaccine Developer) and the global health nonprofit organisation PATH and its Malaria Vaccine Initiative program (PATH/MVI, Funder-Development Partner), (RTS, S) (NCT00866619). The respondents included teams from four clinical research centres (two centres in Ghana and two in Tanzania) and various collaborating partners. This paper analyses responses to the question: What is Health Research for Development? Based on the stakeholders' experience the respondents offered many ways of defining Health Research for Development. The responses fell into four broad themes: i) Equitable Partnerships; ii) System Sustainability; iii) Addressing Local Health Targets, and iv) Regional Commitment to Benefit Sharing. Through defining Health Research for Development six key learning points were generated from the four result themes: 1) Ensure there is local research leadership working with the collaborative partnership, and local healthcare system, to align the project agenda and activities with local research and health priorities; 2) Know the country-specific context - map the social, health, legislative and political setting; 3) Define an explicit development component and plan of action in a research project; 4) Address the barriers and opportunities to sustain system capacity. 5) Support decentralised health system decision-making to facilitate the translation pathway; 6) Govern, monitor and evaluate the development components of health research partnerships. Overall, equity and unity between partners are required to deliver health research for development. © 2017 John Wiley & Sons Ltd.

Key Performance Indicators to Measure Improvement After Implementation of Total Laboratory Automation Abbott Accelerator a3600.

PubMed

Miler, Marijana; Nikolac Gabaj, Nora; Dukic, Lora; Simundic, Ana-Maria

2017-12-27

The aim of the study was to estimate improvement of work efficiency in the laboratory after implementation of total laboratory automation (TLA) by Abbott Accelerator a3600 in the laboratory with measuring different key performance indicators (KPIs) before and after TLA implementation. The objective was also to recommend steps for defining KPIs in other laboratories. For evaluation of improvement 10 organizational and/or technical KPIs were defined for all phases of laboratory work and measured before (November 2013) and after (from 2015 to 2017) TLA implementation. Out of 10 defined KPIs, 9 were successfully measured and significantly improved. Waiting time for registration of samples in the LIS was significantly reduced from 16 (9-28) to 9 (6-16) minutes after TLA (P < 0.001). After TLA all tests were performed at core biochemistry analyzers which significantly reduced walking distance for sample management (for more than 800 m per worker) and number of tube touches (for almost 50%). Analyzers downtime and engagement time for analyzers maintenance was reduced for 50 h and 28 h per month, respectively. TLA eliminated manual dilution of samples with extreme results with sigma values increment from 3.4 to >6 after TLA. Although median turnaround time TAT for potassium and troponin was higher (for approximately 20 min), number of outliers with TAT >60 min expressed as sigma values were satisfying (>3). Implementation of the TLA improved the most of the processes in our laboratory with 9 out of 10 properly defined and measured KPIs. With proper planning and defining of KPIs, every laboratory could measure changes in daily workflow.

Lessons from the Canadian national health information technology plan for the United States: opinions of key Canadian experts.

PubMed

Zimlichman, Eyal; Rozenblum, Ronen; Salzberg, Claudia A; Jang, Yeona; Tamblyn, Melissa; Tamblyn, Robyn; Bates, David W

2012-01-01

To summarize the Canadian health information technology (HIT) policy experience and impart lessons learned to the US as it determines its policy in this area. Qualitative analysis of interviews with identified key stakeholders followed by an electronic survey. We conducted semi-structured interviews with 29 key Canadian HIT policy and opinion leaders and used a grounded theory approach to analyze the results. The informant sample was chosen to provide views from different stakeholder groups including national representatives and regional representatives from three Canadian provinces. Canadian informants believed that much of the current US direction is positive, especially regarding incentives and meaningful use, but that there are key opportunities for the US to emphasize direct engagement with providers, define a clear business case for them, sponsor large scale evaluations to assess HIT impact in a broad array of settings, determine standards but also enable access to resources needed for mid-course corrections of standards when issues are identified, and, finally, leverage implementation of digital imaging systems. Not all stakeholder groups were included, such as providers or patients. In addition, as in all qualitative research, a selection bias could be present due to the relatively small sample size. Based on Canadian experience with HIT policy, stakeholders identified as lessons for the US the need to increase direct engagement with providers and the importance of defining the business case for HIT, which can be achieved through large scale evaluations, and of recognizing and leveraging successes as they emerge.

Societal-Equity-Enhancing Criteria and Facility-Host Incentives Supporting Five Key Elements in the January 2012 Blue Ribbon Commission Report - 13015

DOE Office of Scientific and Technical Information (OSTI.GOV)

Eriksson, Leif G.; Dials, George E.; George, Critz H.

2013-07-01

In February 2009, the Obama Administration announced it would abandon USA's only candidate SNF/HLW-disposal facility since 1987. In 2010, all related activities were stopped and the Blue Ribbon Commission on America's Nuclear Future was established 'to recommend a new strategy for managing the back end of the nuclear fuel cycle', which it did in January 2012, emphasizing eight key elements. However, Key Element 1, 'A new, consent-based approach to siting future nuclear facilities', is qualitative/indeterminate rather than quantitative/measurable. It is thus highly-susceptible to semantic permutations that could extend rather than, as intended, expedite the siting of future nuclear facilities unlessmore » it also defines: a) Whose consent is needed?; and b) What constitutes consent? The following 'generic', radiation-risk- and societal-equity-based criteria address these questions: 1. Identify areas affected by projected radiation and other health risks from: a. The proposed nuclear facility (facility stakeholders); and b. The related nuclear-materials-transportation routes (transportation stakeholders); then 2. Surround each stakeholder area with a buffer zone and use this enlarged foot print to identify: a. Stakeholder hosts; and b. Areas not hosting any stakeholder category (interested parties). 3. Define 'consent-based' as being at least 60 percent of the 'population' in the respective stakeholder category and apply this yardstick to both 'in favor' and 'against' votes. Although criteria 1 and 2 also need facility-based definitions to make Key Element 1 measurable, the described siting approach, augmented by related facility-host incentives, would expedite the schedule and reduce the cost for achieving Key Elements 4-6 and 8, politics permitting. (authors)« less

Human Factors Design Of Automated Highway Systems: Scenario Definition

DOT National Transportation Integrated Search

1995-09-01

Attention to driver acceptance and performance issues during system design will be key to the success of the Automated Highway System (AHS). A first step in the process of defining driver roles and driver-system interface requirements of AHS is the d...

How to Write Effective Procedure Manuals.

ERIC Educational Resources Information Center

Wold, Geoffrey H.

1987-01-01

Describes six key guidelines for developing usable procedure manuals, including defining the audience; designing a standard format; preparing an outline; using a clear, concise writing style; testing the procedures; and "finalizing" the product with indices, glossaries, appendices, and section tabs. Well-written manuals can increase…

Computational Exposure Science: An Emerging Discipline to Support 21st-Century Risk Assessment

EPA Science Inventory

Background: Computational exposure science represents a frontier of environmental science that is emerging and quickly evolving.Objectives: In this commentary, we define this burgeoning discipline, describe a framework for implementation, and review some key ongoing research elem...

Misconceptions about Psychological Science: A Review

ERIC Educational Resources Information Center

Hughes, Sean; Lyddy, Fiona; Lambe, Sinead

2013-01-01

This article provides an overview of the available evidence on psychological misconceptions, including key findings, current directions and emerging issues for investigation. We begin by defining misconceptions and then examine their prevalence and persistence, discuss their implications for student learning and highlight potential strategies to…

MINI REVIEW - EPIGENETIC PROCESSES AND CANCER RISK ASSESSMENT

EPA Science Inventory

Abstract: The U.S. Environmental Protection Agency's Guidelines for Carcinogen Risk Assessment encourages the use of mechanistic data in the assessment of human cancer risk at low (environmental) exposure levels. The key events that define a particular mode of action for tumor fo...

Professional Training of Economists at Polish Universities

ERIC Educational Resources Information Center

Ogienko, Olena

2016-01-01

Polish experience in professional training of economists at university has been generalized. Structural, content and procedural peculiarities of the training have been defined. It has been proved that key factors for reforming economic education in Poland are globalization, internationalization, integration, technologization and informatization.…

A Writing Teacher in the Physics Classroom.

ERIC Educational Resources Information Center

Kirkpatrick, Larry D.; Pittendrigh, Adele S.

1984-01-01

Describes a series of writing exercises specifically designed to improve students' comprehension of physics. Students are given a RAFT which defines their role, audience, format, and task. Format for writing essays focuses on key ideas, general ideas, specific cases, and additional insights. (JM)

Report: Ongoing Management Improvements and Further Evaluation Vital to EPA Stewardship and Voluntary Programs

EPA Pesticide Factsheets

Report #2005-P-00007, February 17, 2005. We asked stakeholders to define stewardship, list motivators and obstacles to participating in stewardship programs, and outline key roles for EPA to play to foster participating in environmental stewardship.

Heparin/heparan sulfate 6-O-sulfatase from Flavobacterium heparinum: integrated structural and biochemical investigation of enzyme active site and substrate specificity.

PubMed

Myette, James R; Soundararajan, Venkataramanan; Shriver, Zachary; Raman, Rahul; Sasisekharan, Ram

2009-12-11

Heparin and heparan sulfate glycosaminoglycans (HSGAGs) comprise a chemically heterogeneous class of sulfated polysaccharides. The development of structure-activity relationships for this class of polysaccharides requires the identification and characterization of degrading enzymes with defined substrate specificity and enzymatic activity. Toward this end, we report here the molecular cloning and extensive structure-function analysis of a 6-O-sulfatase from the Gram-negative bacterium Flavobacterium heparinum. In addition, we report the recombinant expression of this enzyme in Escherichia coli in a soluble, active form and identify it as a specific HSGAG sulfatase. We further define the mechanism of action of the enzyme through biochemical and structural studies. Through the use of defined substrates, we investigate the kinetic properties of the enzyme. This analysis was complemented by homology-based molecular modeling studies that sought to rationalize the substrate specificity of the enzyme and mode of action through an analysis of the active-site topology of the enzyme including identifying key enzyme-substrate interactions and assigning key amino acids within the active site of the enzyme. Taken together, our structural and biochemical studies indicate that 6-O-sulfatase is a predominantly exolytic enzyme that specifically acts on N-sulfated or N-acetylated 6-O-sulfated glucosamines present at the non-reducing end of HSGAG oligosaccharide substrates. This requirement for the N-acetyl or N-sulfo groups on the glucosamine substrate can be explained through eliciting favorable interactions with key residues within the active site of the enzyme. These findings provide a framework that enables the use of 6-O-sulfatase as a tool for HSGAG structure-activity studies as well as expand our biochemical and structural understanding of this important class of enzymes.

Cerebrospinal and Interstitial Fluid Transport via the Glymphatic Pathway Modeled by Optimal Mass Transport

PubMed Central

Ratner, Vadim; Gao, Yi; Lee, Hedok; Elkin, Rena; Nedergaard, Maiken; Benveniste, Helene; Tannenbaum, Allen

2017-01-01

The glymphatic pathway is a system which facilitates continuous cerebrospinal fluid (CSF) and interstitial fluid (ISF) exchange and plays a key role in removing waste products from the rodent brain. Dysfunction of the glymphatic pathway may be implicated in the pathophysiology of Alzheimer's disease. Intriguingly, the glymphatic system is most active during deep wave sleep general anesthesia. By using paramagnetic tracers administered into CSF of rodents, we previously showed the utility of MRI in characterizing a macroscopic whole brain view of glymphatic transport but we have yet to define and visualize the specific flow patterns. Here we have applied an alternative mathematical analysis approach to a dynamic time series of MRI images acquired every 4 min over ∼3 hrs in anesthetized rats, following administration of a small molecular weight paramagnetic tracer into the CSF reservoir of the cisterna magna. We use Optimal Mass Transport (OMT) to model the glymphatic flow vector field, and then analyze the flow to find the network of CSF-ISF flow channels. We use 3D visualization computational tools to visualize the OMT defined network of CSF-ISF flow channels in relation to anatomical and vascular key landmarks from the live rodent brain. The resulting OMT model of the glymphatic transport network agrees largely with the current understanding of the glymphatic transport patterns defined by dynamic contrast-enhanced MRI revealing key CSF transport pathways along the ventral surface of the brain with a trajectory towards the pineal gland, cerebellum, hypothalamus and olfactory bulb. In addition, the OMT analysis also revealed some interesting previously unnoticed behaviors regarding CSF transport involving parenchymal streamlines moving from ventral reservoirs towards the surface of the brain, olfactory bulb and large central veins. PMID:28323163

Cerebrospinal and interstitial fluid transport via the glymphatic pathway modeled by optimal mass transport.

PubMed

Ratner, Vadim; Gao, Yi; Lee, Hedok; Elkin, Rena; Nedergaard, Maiken; Benveniste, Helene; Tannenbaum, Allen

2017-05-15

The glymphatic pathway is a system which facilitates continuous cerebrospinal fluid (CSF) and interstitial fluid (ISF) exchange and plays a key role in removing waste products from the rodent brain. Dysfunction of the glymphatic pathway may be implicated in the pathophysiology of Alzheimer's disease. Intriguingly, the glymphatic system is most active during deep wave sleep general anesthesia. By using paramagnetic tracers administered into CSF of rodents, we previously showed the utility of MRI in characterizing a macroscopic whole brain view of glymphatic transport but we have yet to define and visualize the specific flow patterns. Here we have applied an alternative mathematical analysis approach to a dynamic time series of MRI images acquired every 4min over ∼3h in anesthetized rats, following administration of a small molecular weight paramagnetic tracer into the CSF reservoir of the cisterna magna. We use Optimal Mass Transport (OMT) to model the glymphatic flow vector field, and then analyze the flow to find the network of CSF-ISF flow channels. We use 3D visualization computational tools to visualize the OMT defined network of CSF-ISF flow channels in relation to anatomical and vascular key landmarks from the live rodent brain. The resulting OMT model of the glymphatic transport network agrees largely with the current understanding of the glymphatic transport patterns defined by dynamic contrast-enhanced MRI revealing key CSF transport pathways along the ventral surface of the brain with a trajectory towards the pineal gland, cerebellum, hypothalamus and olfactory bulb. In addition, the OMT analysis also revealed some interesting previously unnoticed behaviors regarding CSF transport involving parenchymal streamlines moving from ventral reservoirs towards the surface of the brain, olfactory bulb and large central veins. Copyright © 2017. Published by Elsevier Inc.

Integrative proteomics and biochemical analyses define Ptc6p as the Saccharomyces cerevisiae pyruvate dehydrogenase phosphatase.

PubMed

Guo, Xiao; Niemi, Natalie M; Coon, Joshua J; Pagliarini, David J

2017-07-14

The pyruvate dehydrogenase complex (PDC) is the primary metabolic checkpoint connecting glycolysis and mitochondrial oxidative phosphorylation and is important for maintaining cellular and organismal glucose homeostasis. Phosphorylation of the PDC E1 subunit was identified as a key inhibitory modification in bovine tissue ∼50 years ago, and this regulatory process is now known to be conserved throughout evolution. Although Saccharomyces cerevisiae is a pervasive model organism for investigating cellular metabolism and its regulation by signaling processes, the phosphatase(s) responsible for activating the PDC in S. cerevisiae has not been conclusively defined. Here, using comparative mitochondrial phosphoproteomics, analyses of protein-protein interactions by affinity enrichment-mass spectrometry, and in vitro biochemistry, we define Ptc6p as the primary PDC phosphatase in S. cerevisiae Our analyses further suggest additional substrates for related S. cerevisiae phosphatases and describe the overall phosphoproteomic changes that accompany mitochondrial respiratory dysfunction. In summary, our quantitative proteomics and biochemical analyses have identified Ptc6p as the primary-and likely sole- S. cerevisiae PDC phosphatase, closing a key knowledge gap about the regulation of yeast mitochondrial metabolism. Our findings highlight the power of integrative omics and biochemical analyses for annotating the functions of poorly characterized signaling proteins. © 2017 by The American Society for Biochemistry and Molecular Biology, Inc.

Engineering intelligent tutoring systems

NASA Technical Reports Server (NTRS)

Warren, Kimberly C.; Goodman, Bradley A.

1993-01-01

We have defined an object-oriented software architecture for Intelligent Tutoring Systems (ITS's) to facilitate the rapid development, testing, and fielding of ITS's. This software architecture partitions the functionality of the ITS into a collection of software components with well-defined interfaces and execution concept. The architecture was designed to isolate advanced technology components, partition domain dependencies, take advantage of the increased availability of commercial software packages, and reduce the risks involved in acquiring ITS's. A key component of the architecture, the Executive, is a publish and subscribe message handling component that coordinates all communication between ITS components.

End user and implementer experiences of mHealth technologies for noncommunicable chronic disease management in young adults: a qualitative systematic review protocol.

PubMed

Slater, Helen; Briggs, Andrew; Stinson, Jennifer; Campbell, Jared M

2017-08-01

The objective of this review is to systematically identify, review and synthesize relevant qualitative research on end user and implementer experiences of mobile health (mHealth) technologies developed for noncommunicable chronic disease management in young adults. "End users" are defined as young people aged 15-24 years, and "implementers" are defined as health service providers, clinicians, policy makers and administrators.The two key questions we wish to systematically explore from identified relevant qualitative studies or studies with qualitative components are.

Satellite Power System. Concept development and evaluation program, volume 6: Construction and operations

NASA Technical Reports Server (NTRS)

Benson, H.; Jenkins, L. M.

1981-01-01

The construction, operation, and maintenance requirements for a solar power satellite, including the space and ground systems, are reviewed. The basic construction guidelines are explained, and construction location options are discussed. The space construction tasks, equipment, and base configurations are discussed together with the operations required to place a solar power satellite in geosynchronous orbit. A rectenna construction technique is explained, and operation with the grid is defined. Maintenance requirements are summarized for the entire system. Key technology issues required for solar power satellite construction operations are defined.

Adoption and Design of Emerging Dietary Policies to Improve Cardiometabolic Health in the US.

PubMed

Huang, Yue; Pomeranz, Jennifer; Wilde, Parke; Capewell, Simon; Gaziano, Tom; O'Flaherty, Martin; Kersh, Rogan; Whitsel, Laurie; Mozaffarian, Dariush; Micha, Renata

2018-04-14

Suboptimal diet is a leading cause of cardiometabolic disease and economic burdens. Evidence-based dietary policies within 5 domains-food prices, reformulation, marketing, labeling, and government food assistance programs-appear promising at improving cardiometabolic health. Yet, the extent of new dietary policy adoption in the US and key elements crucial to define in designing such policies are not well established. We created an inventory of recent US dietary policy cases aiming to improve cardiometabolic health and assessed the extent of their proposal and adoption at federal, state, local, and tribal levels; and categorized and characterized the key elements in their policy design. Recent federal dietary policies adopted to improve cardiometabolic health include reformulation (trans-fat elimination), marketing (mass-media campaigns to increase fruits and vegetables), labeling (Nutrition Facts Panel updates, menu calorie labeling), and food assistance programs (financial incentives for fruits and vegetables in the Supplemental Nutrition Assistance Program (SNAP) and Women, Infant and Children (WIC) program). Federal voluntary guidelines have been proposed for sodium reformulation and food marketing to children. Recent state proposals included sugar-sweetened beverage (SSB) taxes, marketing restrictions, and SNAP restrictions, but few were enacted. Local efforts varied significantly, with certain localities consistently leading in the proposal or adoption of relevant policies. Across all jurisdictions, most commonly selected dietary targets included fruits and vegetables, SSBs, trans-fat, added sugar, sodium, and calories; other healthy (e.g., nuts) or unhealthy (e.g., processed meats) factors were largely not addressed. Key policy elements to define in designing these policies included those common across domains (e.g., level of government, target population, dietary target, dietary definition, implementation mechanism), and domain-specific (e.g., media channels for food marketing domain) or policy-specific (e.g., earmarking for taxes) elements. Characteristics of certain elements were similarly defined (e.g., fruit and vegetable definition, warning language used in SSB warning labels), while others varied across cases within a policy (e.g., tax base for SSB taxes). Several key elements were not always sufficiently characterized in government documents, and dietary target selections and definitions did not consistently align with the evidence-base. These findings highlight recent action on dietary policies to improve cardiometabolic health in the US; and key elements necessary to design such policies.

Defining the Environment in Gene–Environment Research: Lessons From Social Epidemiology

PubMed Central

Daw, Jonathan; Freese, Jeremy

2013-01-01

In this article, we make the case that social epidemiology provides a useful framework to define the environment within gene–environment (G×E) research. We describe the environment in a multilevel, multidomain, longitudinal framework that accounts for upstream processes influencing health outcomes. We then illustrate the utility of this approach by describing how intermediate levels of social organization, such as neighborhoods or schools, are key environmental components of G×E research. We discuss different models of G×E research and encourage public health researchers to consider the value of including genetic information from their study participants. We also encourage researchers interested in G×E interplay to consider the merits of the social epidemiology model when defining the environment. PMID:23927514

Addiction recovery: its definition and conceptual boundaries.

PubMed

White, William L

2007-10-01

The addiction field's failure to achieve consensus on a definition of "recovery" from severe and persistent alcohol and other drug problems undermines clinical research, compromises clinical practice, and muddles the field's communications to service constituents, allied service professionals, the public, and policymakers. This essay discusses 10 questions critical to the achievement of such a definition and offers a working definition of recovery that attempts to meet the criteria of precision, inclusiveness, exclusiveness, measurability, acceptability, and simplicity. The key questions explore who has professional and cultural authority to define recovery, the defining ingredients of recovery, the boundaries (scope and depth) of recovery, and temporal benchmarks of recovery (when recovery begins and ends). The process of defining recovery touches on some of the most controversial issues within the addictions field.

CAD/CAM approach to improving industry productivity gathers momentum

NASA Technical Reports Server (NTRS)

Fulton, R. E.

1982-01-01

Recent results and planning for the NASA/industry Integrated Programs for Aerospace-Vehicle Design (IPAD) program for improving productivity with CAD/CAM methods are outlined. The industrial group work is being mainly done by Boeing, and progress has been made in defining the designer work environment, developing requirements and a preliminary design for a future CAD/CAM system, and developing CAD/CAM technology. The work environment was defined by conducting a detailed study of a reference design process, and key software elements for a CAD/CAM system have been defined, specifically for interactive design or experiment control processes. Further work is proceeding on executive, data management, geometry and graphics, and general utility software, and dynamic aspects of the programs being developed are outlined

Conceptual design of an advanced Stirling conversion system for terrestrial power generation

NASA Technical Reports Server (NTRS)

1988-01-01

A free piston Stirling engine coupled to an electric generator or alternator with a nominal kWe power output absorbing thermal energy from a nominal 100 square meter parabolic solar collector and supplying electric power to a utility grid was identified. The results of the conceptual design study of an Advanced Stirling Conversion System (ASCS) were documented. The objectives are as follows: define the ASCS configuration; provide a manufacturability and cost evaluation; predict ASCS performance over the range of solar input required to produce power; estimate system and major component weights; define engine and electrical power condidtioning control requirements; and define key technology needs not ready by the late 1980s in meeting efficiency, life, cost, and with goalds for the ASCS.

Light Activated Cell Migration in Synthetic Extracellular Matrices

PubMed Central

Guo, Qiongyu; Wang, Xiaobo; Tibbitt, Mark W.; Anseth, Kristi S.; Montell, Denise J.; Elisseeff, Jennifer H.

2012-01-01

Synthetic extracellular matrices provide a framework in which cells can be exposed to defined physical and biological cues. However no method exists to manipulate single cells within these matrices. It is desirable to develop such methods in order to understand fundamental principles of cell migration and define conditions that support or inhibit cell movement within these matrices. Here, we present a strategy for manipulating individual mammalian stem cells in defined synthetic hydrogels through selective optical activation of Rac, which is an intracellular signaling protein that plays a key role in cell migration. Photoactivated cell migration in synthetic hydrogels depended on mechanical and biological cues in the biomaterial. Real-time hydrogel photodegradation was employed to create geometrically defined channels and spaces in which cells could be photoactivated to migrate. Cell migration speed was significantly higher in the photo-etched channels and cells could easily change direction of movement compared to the bulk hydrogels. PMID:22889487

Performance Management and Optimization of Semiconductor Design Projects

NASA Astrophysics Data System (ADS)

Hinrichs, Neele; Olbrich, Markus; Barke, Erich

2010-06-01

The semiconductor industry is characterized by fast technological changes and small time-to-market windows. Improving productivity is the key factor to stand up to the competitors and thus successfully persist in the market. In this paper a Performance Management System for analyzing, optimizing and evaluating chip design projects is presented. A task graph representation is used to optimize the design process regarding time, cost and workload of resources. Key Performance Indicators are defined in the main areas cost, profit, resources, process and technical output to appraise the project.

Typed Multiset Rewriting Specifications of Security Protocols

DTIC Science & Technology

2011-10-01

to define the type of a tuple as the sequence of the types of its components. Therefore, if A is a principal name and kA is a public key for A, the...tuple (A, kA ) would have type “principal × pubK A” (the Cartesian product symbol “×” is the standard constructor for tuple types). This construction...allows us to associate a generic principal with A’s public key: if B is another principal, then (B, kA ) will have this type as well. We will often need

3.8 Proposed approach to uncertainty quantification and sensitivity analysis in the next PA

DOE Office of Scientific and Technical Information (OSTI.GOV)

Flach, Greg; Wohlwend, Jen

2017-10-02

This memorandum builds upon Section 3.8 of SRNL (2016) and Flach (2017) by defining key error analysis, uncertainty quantification, and sensitivity analysis concepts and terms, in preparation for the next E-Area Performance Assessment (WSRC 2008) revision.

Development of an adverse outcome pathway for acetylcholinesterase inhibition leading to acute mortality

EPA Science Inventory

Adverse outcome pathways (AOPs) are designed to describe linkages of key events (KEs) within a biological pathway that result in an adverse outcome associated with chemical perturbation of a well-defined molecular initiating event (MIE). Risk assessors have traditionally relied ...

Integrating Critical Spreadsheet Competencies into the Accounting Curriculum

ERIC Educational Resources Information Center

Walters, L. Melissa; Pergola, Teresa M.

2012-01-01

The American Institute of Certified Public Accountants (AICPA) and the International Accounting Education Standards Board (IAESB) identify spreadsheet technology as a key information technology (IT) competency for accounting professionals. However requisite spreadsheet competencies are not specifically defined by the AICPA or IAESB nor are they…

Knowledge Management and Reference Services

ERIC Educational Resources Information Center

Gandhi, Smiti

2004-01-01

Many corporations are embracing knowledge management (KM) to capture the intellectual capital of their employees. This article focuses on KM applications for reference work in libraries. It defines key concepts of KM, establishes a need for KM for reference services, and reviews various KM initiatives for reference services.

Effective Instruction: A Mathematics Coach's Perspective

ERIC Educational Resources Information Center

Nebesniak, Amy L.

2012-01-01

Effective instruction is multifaceted, dependent largely on the context and, consequently, on numerous variables. Although "effective instruction" is difficult to define, in the author's experience--and as the work of mathematics education specialists and researchers indicates--three key features of quality instruction stand out: (1) Teaching…

INITIAL SCREENING OF THERMAL DESORPTION FOR SOIL REMEDIATION

EPA Science Inventory

The purpose of the paper is to present procedures for collecting and evaluating key data that affect the potential application of thermal desorption for a specific site. These data are defined as 'criticalsuccess factors'. The screening prodcedure can be used to peerform an ini...

Microelectronics in Education

ERIC Educational Resources Information Center

Orton, Richard J. J.

2011-01-01

The history and meaning of the term "microelectronics" is reviewed, followed by a discussion of the key inventions of the Intel microprocessor in 1971 and the Texas Instruments electronic pocket calculator in 1975. The six characteristic features of microelectronic components are then defined. The UK prime minister Jim Callaghan's…

Defining a Computational Framework for the Assessment of Taxonomic Applicability

EPA Science Inventory

The Adverse Outcome Pathway (AOP) framework describes the effects of environmental stressors across multiple scales of biological organization and function. This includes an evaluation of the potential for each key event to occur across a broad range of species in order to determ...

Defining and Measuring Transnational Social Structures

ERIC Educational Resources Information Center

Molina, José Luis; Petermann, Sören; Herz, Andreas

2015-01-01

Transnational social fields and transnational social spaces are often used interchangeably to describe and analyze emergent structures of cross-border formations. In this article, we suggest measuring two key aspects of these social structures: embeddedness and span of migrants' personal networks. While clustered graphs allow assessing…

Air Quality and Heart Health: Managing an Emerging Cardiovascular Risk Factor

EPA Science Inventory

Dr. Cascio will share with a broad range of federal agencies current understanding of the links between air quality and cardiovascular health. The key facts include that air pollution contributes a high attributable health burden. That certain well-defined vulnerable subpopulat...

Mineral-associated organic matter: are we now on the right path to accurately measuring and modelling it?

NASA Astrophysics Data System (ADS)

Cotrufo, M. F.

2017-12-01

Mineral-associated organic matter (MAOM) is the largest and most persistent pool of carbon in soil. Understanding and correctly modeling its dynamic is key to suggest management practices that can augment soil carbon storage for climate change mitigation, as well as increase soil organic matter (SOM) stocks to support soil health on the long-term. In the Microbial Efficiency Mineral Stabilization (MEMS) framework we proposed that, contrary to what originally thought, this form of persistent SOM is derived from the labile components of plant inputs, through their efficient microbial processing. I will present results from several experiments using dual isotope labeling of plant inputs that largely confirm this opinion, and point to the key role of dissolved organic matter in MAOM formation, and to the dynamic nature of the outer layer of MAOM. I will also show how we are incorporating this understanding in a new SOM model, which uses physically defined measurable pools rather than turnover-defined pools to forecast C cycling in soil.

An E-Hospital Security Architecture

NASA Astrophysics Data System (ADS)

Tian, Fang; Adams, Carlisle

In this paper, we introduce how to use cryptography in network security and access control of an e-hospital. We first define the security goal of the e-hospital system, and then we analyze the current application system. Our idea is proposed on the system analysis and the related regulations of patients' privacy protection. The security of the whole application system is strengthened through layered security protection. Three security domains in the e-hospital system are defined according to their sensitivity level, and for each domain, we propose different security protections. We use identity based cryptography to establish secure communication channel in the backbone network and policy based cryptography to establish secure communication channel between end users and the backbone network. We also use policy based cryptography in the access control of the application system. We use a symmetric key cryptography to protect the real data in the database. The identity based and policy based cryptography are all based on elliptic curve cryptography—a public key cryptography.

Around and beyond 53BP1 Nuclear Bodies

PubMed Central

Fernandez-Vidal, Anne; Vignard, Julien

2017-01-01

Within the nucleus, sub-nuclear domains define territories where specific functions occur. Nuclear bodies (NBs) are dynamic structures that concentrate nuclear factors and that can be observed microscopically. Recently, NBs containing the p53 binding protein 1 (53BP1), a key component of the DNA damage response, were defined. Interestingly, 53BP1 NBs are visualized during G1 phase, in daughter cells, while DNA damage was generated in mother cells and not properly processed. Unlike most NBs involved in transcriptional processes, replication has proven to be key for 53BP1 NBs, with replication stress leading to the formation of these large chromatin domains in daughter cells. In this review, we expose the composition and organization of 53BP1 NBs and focus on recent findings regarding their regulation and dynamics. We then concentrate on the importance of the replication stress, examine the relation of 53BP1 NBs with DNA damage and discuss their dysfunction. PMID:29206178

Defining disaster resilience: comparisons from key stakeholders involved in emergency management in Victoria, Australia.

PubMed

Goode, Natassia; Salmon, Paul M; Spencer, Caroline; McArdle, Dudley; Archer, Frank

2017-01-01

Three years after the introduction of the National Strategy for Disaster Resilience there remains no unanimously adopted definition of disaster resilience within Australia's emergency management sector. The aim of this study is to determine what the concept means to key stakeholders in the emergency management sector in the Australian State of Victoria, and how these conceptualisations overlap and diverge. Via an online survey, 113 people were asked how they define disaster resilience in their work in the emergency management sector. A data mining software tool, Leximancer, was employed to uncover the relationships between the definitions provided. The findings show that stakeholders see resilience as an 'ability' that encompasses emergency management activities and personal responsibility. However, the findings also highlight some possible points of conflict between stakeholders. In addition, the paper outlines and discusses a number of potential consequences for the implementation and the success of the resilience-based approach in Australia. © 2017 The Author(s). Disasters © Overseas Development Institute, 2017.

A TRPV2 interactome-based signature for prognosis in glioblastoma patients.

PubMed

Doñate-Macián, Pau; Gómez, Antonio; Dégano, Irene R; Perálvarez-Marín, Alex

2018-04-06

Proteomics aids to the discovery and expansion of protein-protein interaction networks, which are key to understand molecular mechanisms in physiology and physiopathology, but also to infer protein function in a guilt-by-association fashion. In this study we use a systematic protein-protein interaction membrane yeast two-hybrid method to expand the interactome of TRPV2, a cation channel related to nervous system development. After validation of the interactome in silico , we define a TRPV2-interactome signature combining proteomics with the available physio-pathological data in Disgenet to find interactome-disease associations, highlighting nervous system disorders and neoplasms. The TRPV2-interactome signature against available experimental data is capable of discriminating overall risk in glioblastoma multiforme prognosis, progression, recurrence, and chemotherapy resistance. Beyond the impact on glioblastoma physiopathology, this study shows that combining systematic proteomics with in silico methods and available experimental data is key to open new perspectives to define novel biomarkers for diagnosis, prognosis and therapeutics in disease.

A TRPV2 interactome-based signature for prognosis in glioblastoma patients

PubMed Central

Dégano, Irene R.; Perálvarez-Marín, Alex

2018-01-01

Proteomics aids to the discovery and expansion of protein-protein interaction networks, which are key to understand molecular mechanisms in physiology and physiopathology, but also to infer protein function in a guilt-by-association fashion. In this study we use a systematic protein-protein interaction membrane yeast two-hybrid method to expand the interactome of TRPV2, a cation channel related to nervous system development. After validation of the interactome in silico, we define a TRPV2-interactome signature combining proteomics with the available physio-pathological data in Disgenet to find interactome-disease associations, highlighting nervous system disorders and neoplasms. The TRPV2-interactome signature against available experimental data is capable of discriminating overall risk in glioblastoma multiforme prognosis, progression, recurrence, and chemotherapy resistance. Beyond the impact on glioblastoma physiopathology, this study shows that combining systematic proteomics with in silico methods and available experimental data is key to open new perspectives to define novel biomarkers for diagnosis, prognosis and therapeutics in disease. PMID:29719613

Status of the Planet Formation Imager (PFI) concept

NASA Astrophysics Data System (ADS)

Ireland, Michael J.; Monnier, John D.; Kraus, Stefan; Isella, Andrea; Minardi, Stefano; Petrov, Romain; ten Brummelaar, Theo; Young, John; Vasisht, Gautam; Mozurkewich, David; Rinehart, Stephen; Michael, Ernest A.; van Belle, Gerard; Woillez, Julien

2016-08-01

The Planet Formation Imager (PFI) project aims to image the period of planet assembly directly, resolving structures as small as a giant planet's Hill sphere. These images will be required in order to determine the key mechanisms for planet formation at the time when processes of grain growth, protoplanet assembly, magnetic fields, disk/planet dynamical interactions and complex radiative transfer all interact - making some planetary systems habitable and others inhospitable. We will present the overall vision for the PFI concept, focusing on the key technologies and requirements that are needed to achieve the science goals. Based on these key requirements, we will define a cost envelope range for the design and highlight where the largest uncertainties lie at this conceptual stage.

Temporal steering and security of quantum key distribution with mutually unbiased bases against individual attacks

NASA Astrophysics Data System (ADS)

Bartkiewicz, Karol; Černoch, Antonín; Lemr, Karel; Miranowicz, Adam; Nori, Franco

2016-06-01

Temporal steering, which is a temporal analog of Einstein-Podolsky-Rosen steering, refers to temporal quantum correlations between the initial and final state of a quantum system. Our analysis of temporal steering inequalities in relation to the average quantum bit error rates reveals the interplay between temporal steering and quantum cloning, which guarantees the security of quantum key distribution based on mutually unbiased bases against individual attacks. The key distributions analyzed here include the Bennett-Brassard 1984 protocol and the six-state 1998 protocol by Bruss. Moreover, we define a temporal steerable weight, which enables us to identify a kind of monogamy of temporal correlation that is essential to quantum cryptography and useful for analyzing various scenarios of quantum causality.

Distinguishability of quantum states and shannon complexity in quantum cryptography

NASA Astrophysics Data System (ADS)

Arbekov, I. M.; Molotkov, S. N.

2017-07-01

The proof of the security of quantum key distribution is a rather complex problem. Security is defined in terms different from the requirements imposed on keys in classical cryptography. In quantum cryptography, the security of keys is expressed in terms of the closeness of the quantum state of an eavesdropper after key distribution to an ideal quantum state that is uncorrelated to the key of legitimate users. A metric of closeness between two quantum states is given by the trace metric. In classical cryptography, the security of keys is understood in terms of, say, the complexity of key search in the presence of side information. In quantum cryptography, side information for the eavesdropper is given by the whole volume of information on keys obtained from both quantum and classical channels. The fact that the mathematical apparatuses used in the proof of key security in classical and quantum cryptography are essentially different leads to misunderstanding and emotional discussions [1]. Therefore, one should be able to answer the question of how different cryptographic robustness criteria are related to each other. In the present study, it is shown that there is a direct relationship between the security criterion in quantum cryptography, which is based on the trace distance determining the distinguishability of quantum states, and the criterion in classical cryptography, which uses guesswork on the determination of a key in the presence of side information.

Lean Information Management: Criteria For Selecting Key Performance Indicators At Shop Floor

NASA Astrophysics Data System (ADS)

Iuga, Maria Virginia; Kifor, Claudiu Vasile; Rosca, Liviu-Ion

2015-07-01

Most successful organizations worldwide use key performance indicators as an important part of their corporate strategy in order to forecast, measure and plan their businesses. Performance metrics vary in their purpose, definition and content. Therefore, the way organizations select what they think are the optimal indicators for their businesses varies from company to company, sometimes even from department to department. This study aims to answer the question of what is the most suitable way to define and select key performance indicators. More than that, it identifies the right criteria to select key performance indicators at shop floor level. This paper contributes to prior research by analysing and comparing previously researched selection criteria and proposes an original six-criteria-model, which caters towards choosing the most adequate KPIs. Furthermore, the authors take the research a step further by further steps to closed research gaps within this field of study.

Teaching for Cross Cultural Understanding.

ERIC Educational Resources Information Center

Arlington County Public Schools, VA.

The document contains materials prepared for a workshop designed to foster cross-cultural understanding in junior high school teachers. It is presented in six sections. Section I defines several key concepts such as culture, racism, ethnic diversity, stereotype, pluralism, ethnic encapsulization, and types of teaching styles and dialects.…

Introduction to the Educational Sciences.

ERIC Educational Resources Information Center

Mialaret, G.; And Others

This volume looks at the comparative study of educational policies, issues, and problems covering developments in education worldwide. Some educators define education as an applied art that attempts to use scientific approaches. This collection of articles presents the European viewpoint, in which scholars consider key elements in the study of…

The ULT trxG Fatcors play a role in Arabidopsis Fertilization

USDA-ARS?s Scientific Manuscript database

Trithorax group (trxG) and Polycomb group (PcG) proteins are epigenetic modifiers that play key roles in eukaryotic development by promoting active or repressive gene expression states, respectively. Although PcG proteins have well-defined roles in controlling developmental transitions, cell fate de...

Effect of a zero g environment on flammability limits as determined using a standard flammability tube apparatus

NASA Technical Reports Server (NTRS)

Strehlow, R. A.; Reuss, D. L.

1980-01-01

Flammability limits in a zero gravity environment were defined. Key aspects of a possible spacelab experiment were investigated analytically, experimentally on the bench, and in drop tower facilities. A conceptual design for a spacelab experiment was developed.

Strategic Planning for Educational Reform and Improvement.

ERIC Educational Resources Information Center

D'Amico, Joseph J.

1988-01-01

Defines strategic planning, outlines its key elements and activities, and summarizes the difficulties of applying a top-down, profit-driven process to education. Explains Strategic Planning for Educational Reform and Improvement (SPERI), a set of manageable, concise procedures for top school administrators. Describes SPERI applications in an…

Strategic Enrollment Management: A Primer for Campus Administrators.

ERIC Educational Resources Information Center

Dolence, Michael G.

This booklet provides an overview of key concepts of Strategic Enrollment Management (SEM), a comprehensive process designed to help institutions of higher education achieve and maintain the optimum student recruitment, retention, and graduation rates. "Optimum" here is defined within the academic context of the particular institution. Primary…

AN INDICATOR OF POTENTIAL STREAM WOOD CONTRIBUTION FOR RIPARIAN FORESTS

EPA Science Inventory

In northwestern Oregon a key function of riparian forests is to provide wood to the stream network. This function is a prominent feature of Federal and State forest practices in the region. Thus, defining indicators which are associated with this function are important for desi...

Accommodation Outcomes and the ICF Framework

ERIC Educational Resources Information Center

Schreuer, Naomi

2009-01-01

Accommodation of the environment and technology is one of the key mediators of adjustment to disability and participation in community. In this article, accommodations are tested empirically as facilitators of return to work and participation, as defined by the "International Classification of Disability, Function, and Health" (ICF) and…

The Balanced Reading Program: Helping All Students Achieve Success.

ERIC Educational Resources Information Center

Blair-Larsen, Susan M., Ed.; Williams, Kathryn A., Ed.

This book explains the methodologies, techniques, strategies, and knowledge base necessary to achieve a balanced reading program. The book's contributors define the key elements in a balanced reading program and provide guidelines for implementing a balanced instructional program in the classroom. Following an introduction which addresses…

Framework for Assessing Environmental, Social, and Economic Sustainability of ICT Organizations

ERIC Educational Resources Information Center

Odeh, Khuloud

2013-01-01

Key challenges that confront the Information and Communication Technology (ICT) industry today in defining and achieving social, environmental, and economic sustainability goals include identifying sustainable operating standards and best practices and measuring and assessing performance against those practices. The industry lacks a framework for…

Towards bioavailability-based soil criteria: Past, present and future perspectives

USDA-ARS?s Scientific Manuscript database

Bioavailability has been used as a key indicator in chemical risk assessment, yet it is a poorly quantified risk factor. Worldwide, the framework used to assess potentially contaminated sites is similar and the decisions are based on threshold contaminant concentration. The uncertainty in the defin...

Key Odorants Regulate Food Attraction in Drosophila melanogaster

PubMed Central

Giang, Thomas; He, Jianzheng; Belaidi, Safaa; Scholz, Henrike

2017-01-01

In insects, the search for food is highly dependent on olfactory sensory input. Here, we investigated whether a single key odorant within an odor blend or the complexity of the odor blend influences the attraction of Drosophila melanogaster to a food source. A key odorant is defined as an odorant that elicits a difference in the behavioral response when two similar complex odor blends are offered. To validate that the observed behavioral responses were elicited by olfactory stimuli, we used olfactory co-receptor Orco mutants. We show that within a food odor blend, ethanol functions as a key odorant. In addition to ethanol other odorants might serve as key odorants at specific concentrations. However, not all odorants are key odorants. The intensity of the odor background influences the attractiveness of the key odorants. Increased complexity is only more attractive in a concentration-dependent range for single compounds in a blend. Orco is necessary to discriminate between two similarly attractive odorants when offered as single odorants and in food odor blends, supporting the importance of single odorant recognition in odor blends. These data strongly indicate that flies use more than one strategy to navigate to a food odor source, depending on the availability of key odorants in the odor blend and the alternative odor offered. PMID:28928642

Key Results of Interaction Models with Centering

ERIC Educational Resources Information Center

Afshartous, David; Preston, Richard A.

2011-01-01

We consider the effect on estimation of simultaneous variable centering and interaction effects in linear regression. We technically define, review, and amplify many of the statistical issues for interaction models with centering in order to create a useful and compact reference for teachers, students, and applied researchers. In addition, we…

Quantitative AOP-based predictions for two aromatase inhibitors evaluating the influence of bioaccumulation on prediction accuracy

EPA Science Inventory

The adverse outcome pathway (AOP) framework can be used to support the use of mechanistic toxicology data as a basis for risk assessment. For certain risk contexts this includes defining, quantitative linkages between the molecular initiating event (MIE) and subsequent key events...

Data Challenges of Leveraging a Simulation to Assess Learning

ERIC Educational Resources Information Center

Gibson, David; Jakl, Peter

2013-01-01

Among the unique affordances of digital simulations are changes in the possibilities for targets as well as the methods of assessment, most significantly, toward integration of thinking with action, embedding of tasks-as-performance of knowledge-in-action, and unobtrusive observational methods. This paper raises and briefly defines key data…

The Library Trustee: A Practical Guidebook. Fifth Edition.

ERIC Educational Resources Information Center

Young, Virginia G., Ed.

This book defines the role and obligations of the library trustee in a wide range of situations and also discusses keys to successful communication between the trustee and library director, staff, and patron. Chapters are: (1) "The Trustee in Today's World" (F. William Summers); (2) "Duties and Responsibilities of Trustees"…

Choice in School: Its Importance and Scope

ERIC Educational Resources Information Center

Yagnamurthy, Sreekanth

2013-01-01

The author reviews various factors defining school choice, and school curricula. A key assumption behind the rhetoric logic of school choice is the notion that parents actually choose from schools of varying quality. If parents choose from high-quality schools, choice policy will enhance educational opportunities. If, however, the considered…

Stamina and Clout Define This Rare Breed.

ERIC Educational Resources Information Center

Harrington-Lueker, Donna

1991-01-01

Takeover artists are a rare breed. Persons hired to put bankrupt school systems back on the road to academic solvency need stamina, clout, and plenty of experience. For all their state-given powers, takeover superintendents must identify key constituencies, build bridges, and promote belief in change from within. (MLH)

The New Economic Equation. Executive Summary.

ERIC Educational Resources Information Center

Joshi, Pamela; Carre, Francoise; Place, Angela; Rayman, Paula

The New Economic Equation Project opened in May 1995 with a 3-day working conference for 50 national leaders. The equation was defined as follows: economic well-being = integration of work, family, and community. Conference participants identified key economic, work, and family concerns facing the United States today. Outreach activities in…

Building Squares and Discovering Patterns

ERIC Educational Resources Information Center

Whitin, David J.; Whitin, Phyllis

2014-01-01

The Common Core State Standards for Mathematics (CCSSM) (CCSSI 2010) define what children should understand and be able to do in K-grade 12. This document also includes a description of key mathematical processes and proficiencies, the Standards for Mathematical Practice (SMPs), which provide an important overview for the kind of robust thinking…

Those Important Things: What Every College President Needs to Know About Marketing and Student Recruitment.

ERIC Educational Resources Information Center

Sevier, Robert A.

1996-01-01

College presidents are offered nine key suggestions for marketing and student recruitment: beginning with vision; defining marketing broadly; creating institutional image; understanding how students make decisions; creating familiarity; competitive positioning; market segmentation; choosing a marketing champion respected by the college community;…

Case Studies of Non-Formal Education by Distance and Open Learning.

ERIC Educational Resources Information Center

Siaciwena, Richard, Ed.

This document contains seven papers from a study of the role of distance learning approaches in enhancing the contribution of nonformal education to socioeconomic development in Africa. "Introduction" (Richard Siaciwena) presents an overview of the research project and defines key terms related to nonformal education. "Ghana: The…

Exploring Wildlife, Unit 1, Colorado Division of Wildlife.

ERIC Educational Resources Information Center

Hooper, Jon K.; Smith, Dwight R.

This booklet on wildlife is part of a series to encourage youth to pursue environmental projects. The booklet discusses various aspects of wildlife management such as life zones, pollution, predator control, game stocking, habitat improvement, hunting, legislation, and careers. Key words are defined, and suggested activities are listed. (MR)

Sweet vs. Snap! Effective Dispositions in the Media Center

ERIC Educational Resources Information Center

Standard, April

2011-01-01

In "What Defines an Exemplary School Librarian," Jami Jones and Gail Bush make a strong argument that professional disposition is the key to a successful library media program. The authors emphasize the relevance of INTASC standards which specify that teachers must promote "positive social interaction and (develop) healthy and helping…

Glossary for econometrics and epidemiology.

PubMed

Gunasekara, F Imlach; Carter, K; Blakely, T

2008-10-01

Epidemiologists and econometricians are often interested in similar topics-socioeconomic position and health outcomes-but the different languages that epidemiologists and economists use to interpret and discuss their results can create a barrier to mutual communication. This glossary defines key terms used in econometrics and epidemiology to assist in bridging this gap.

7 CFR 226.19 - Outside-school-hours care center provisions.

Code of Federal Regulations, 2012 CFR

2012-01-01

...; Provided, however, That public and private nonprofit centers shall not be eligible to participate in the...-exempt status under the Internal Revenue Code of 1986. (3) Nonresidential public or private nonprofit... beneficiaries. (6) Each outside-school-hours care center must require key operational staff, as defined by the...

7 CFR 226.19 - Outside-school-hours care center provisions.

Code of Federal Regulations, 2014 CFR

2014-01-01

...; Provided, however, That public and private nonprofit centers shall not be eligible to participate in the...-exempt status under the Internal Revenue Code of 1986. (3) Nonresidential public or private nonprofit... beneficiaries. (6) Each outside-school-hours care center must require key operational staff, as defined by the...

Psychological and Pedagogic Support of Children with Health Limitations

ERIC Educational Resources Information Center

Ezhovkina, Elena Vasilyevna; Ryabova, Natalia Vladimirovna

2015-01-01

The article represented theoretic analysis of the literature on the problem of psychological and pedagogic support of disabled children. It defined the following terms: a successfully adapting disabled child, a model, interaction of specialists, psychological and pedagogic support. The article also determined the key components of a successfully…

Avoiding the Ax: How to Keep from Being Downsized or Outsourced.

ERIC Educational Resources Information Center

Bates, Mary Ellen

1997-01-01

Gives guidance in preventing library staff downsizing or outsourcing: remember the competition, read financial reports and periodicals, identify key library executives and patrons, define the library as a "profit center," market the library, make yourself essential and indispensable, remind users of the library's resources, embrace the…

Marketing Power Tools for Building Better Connections.

ERIC Educational Resources Information Center

Goldman, Karen Denard

This paper proposes use of marketing methods to improve college health services and enhance their perceived value. Ten key marketing principles are defined: (1) value of the service as seen by the target population; (2) exchange clients perceive benefits received as exceeding perceived costs; (3) competition offering a better product than the…

Technology and the Prepared Environment for the Third-Plane Child

ERIC Educational Resources Information Center

Castiglione, Cynthia

2016-01-01

Cynthia Castiglione presents Near North Montessori School's (Chicago) adolescent community's approach to technology. Her framework begins with the needs of the adolescent for social independence, social acceptance, and social justice. Using that template, she defines seven keys or characteristics that make up the technological environment:…

The Importance of At-Risk Funding. Policy Analysis

ERIC Educational Resources Information Center

Parker, Emily; Griffith, Michael

2016-01-01

In recent decades, states and districts have moved toward making education more equitable. A key component of equity in education is providing additional funds for economically disadvantaged students, commonly referred to as "at-risk students." At-risk students are most often defined as students who qualify for free or reduced priced…

Performance Measurement for Public Services in Academic and Research Libraries. Occasional Paper Number #9.

ERIC Educational Resources Information Center

Cronin, Mary J.

This paper defines performance measurement as the clarification of objectives and standards, identification of key activities, data collection and analysis, and formative evaluation of services. It then examines some of the factors involved in using performance measurement to evaluate public services activities, and analyzes performance…

Strategies for Defining and Understanding Critical Technology Integration Terms

ERIC Educational Resources Information Center

Fagehi, Ahmed Yahya

2013-01-01

Educational technology scholars believe that teachers should understand how to effectively integrate technology in their teaching. This study identified key terms related to integrating technology in education and investigated the effectiveness of three online instructional strategies (Text-only, Text plus Video, and Text plus Video plus Question)…

Get the Balance Right.

ERIC Educational Resources Information Center

Haddock, Rebecca Jaurigue

Today work goes on 24 hours a day, 7 days a week, and is about acceleration and access. Workers need balance more than ever. In fact, recent college graduates value work/life balance as their key factor in selecting employers. This paper, written for career counselors, defines balance as encompassing emotional, spiritual, physical, and…

Teaching Integrity

ERIC Educational Resources Information Center

Saunders, Sue; Butts, Jennifer Lease

2011-01-01

Integrity is one of those essential yet highly ambiguous concepts. For the purpose of this chapter, integrity is defined as that combination of both attributes and actions that makes entities appear to be whole and ethical, as well as consistent. Like the concepts of leadership or wisdom or community or collaboration, integrity is a key element of…

Allelic barley MLA immune receptors recognize sequence-unrelated avirulence effectors of the powdery mildew pathogen

USDA-ARS?s Scientific Manuscript database

Disease resistance (R) genes encoding intracellular nucleotide-binding domain and leucine-rich repeat proteins (NLRs) are key components of the plant innate immune system and typically detect the presence of isolate-specific avirulence (AVR) effectors from pathogens. NLRs define the fastest evolving...

Hypnosis and Human Development: Interpersonal Influence of Intrapersonal Processes.

ERIC Educational Resources Information Center

Vandenberg, Brian

1998-01-01

Examines the relationship between hypnosis and human development. Defines hypnosis within a communications framework, and identifies essential features of hypnosis in the communicative exchanges of the first months of life; this forces a reconsideration of the understanding of the ontogenesis of hypnosis. Identifies four key features of hypnosis,…

Schools (Students) Exchanging CAD/CAM Files over the Internet.

ERIC Educational Resources Information Center

Mahoney, Gary S.; Smallwood, James E.

This document discusses how students and schools can benefit from exchanging computer-aided design/computer-aided manufacturing (CAD/CAM) files over the Internet, explains how files are exchanged, and examines the problem of selected hardware/software incompatibility. Key terms associated with information search services are defined, and several…

Learning from a Community Festival or Reenactment

ERIC Educational Resources Information Center

Morris, Ronald Vaughan

2008-01-01

Community festivals allow students opportunities to meet key contact people and investigate local resources. Further, the excitement of the social festival is infectious; it encourages learning among people of multiple ages in a common area. Festivals serve to define the community, transmit culture, and allow the community to participate in…

The Influence of Test Conditions on the Performance of Chironomus dilutus and Hyalella azteca in Sediment Toxicity Tests

EPA Science Inventory

In most all sediment toxicity assessments, the performance of organisms in control sediments is a key parameter in defining sediment toxicity, whether through direct statistical comparison to control or by normalizing to control performance to compare results across sites or batc...

A Conceptual Analysis of Key Concepts in Inclusive Education

ERIC Educational Resources Information Center

Boston-Kemple, Thomas Ernest

2012-01-01

The concepts of an inclusive classroom, inclusion, co-teaching, and disability have been called poorly defined and in need of fresh conceptual analyses. In Chapter 1, I respond to this call for further analysis and then demonstrate, using current educational headlines, that these concepts of "an inclusive classroom,"…

Information Security in Higher Education. Professional Paper Series, #5.

ERIC Educational Resources Information Center

Elliott, Raymond; And Others

Intended to generate discussion and motivate proactive intervention in matters of information security, this paper defines and discusses some of the key issues relating to information security on college and university campuses based on in-depth interviews conducted at eight selected higher education institutions of varying size and composition in…

Scientist | Center for Cancer Research

Cancer.gov

KEY ROLES/RESPONSIBILITIES The Scientist I will support research efforts to define the role of transcriptional regulators in myeloid cell development, and their potential role in leukemogenesis.  This work will be accomplished performing both molecular and stem cell biology techniques, cloning and construction of retroviral vectors, quantitative RT-PCR, cloning of conditional

Diet-induced inflammation and mammary ductal development: Alternative activation of estrogen-dependent stromal-epithelial signaling

USDA-ARS?s Scientific Manuscript database

The mechanisms controlling allometric development of the mammary ductal tree have largely been defined through key studies in rodent model systems. The development of this system is known to depend on the integrated actions of pituitary and ovarian hormones, locally produced growth factors, extracel...

Introduction to This Special Issue on Context-Aware Computing.

ERIC Educational Resources Information Center

Moran, Thomas P.; Dourish, Paul

2001-01-01

Discusses pervasive, or ubiquitous, computing; explains the notion of context; and defines context-aware computing as the key to disperse and enmesh computation into our lives. Considers context awareness in human-computer interaction and describes the broad topic areas of the essays included in this special issue. (LRW)

Cassirer's View of Language

ERIC Educational Resources Information Center

Shen, Ying

2009-01-01

Myth is the breakthrough point of [Ernest] Cassirer's philosophy; Art is one of key words to understand his defined language; and Symbolism infiltrates into all aspects of human cultures especially language. The shift of Cassirer from great theories of science and philosophy to the world of art, language, myth, and culture mirrors his bold and…

Internet Basics. ERIC Digest.

ERIC Educational Resources Information Center

Tennant, Roy

The Internet is a worldwide network of computer networks. In the United States, the National Science Foundation Network (NSFNet) serves as the Internet "backbone" (a very high speed network that connects key regions across the country). The NSFNet will likely evolve into the National Research and Education Network (NREN) as defined in…

A First Life with Computerized Business Simulations

ERIC Educational Resources Information Center

Thavikulwat, Precha

2011-01-01

The author discusses the theoretical lens, origins, and environment of his work on computerized business simulations. Key ideas that inform his work include the two dimensions (control and interaction) of computerized simulation, the two ways of representing a natural process (phenotypical and genotypical) in a simulation, which he defines as a…

Progranulin-Associated Primary Progressive Aphasia: A Distinct Phenotype?

ERIC Educational Resources Information Center

Rohrer, Jonathan D.; Crutch, Sebastian J.; Warrington, Elizabeth K.; Warren, Jason D.

2010-01-01

The neuropsychological features of the primary progressive aphasia (PPA) syndromes continue to be defined. Here we describe a detailed neuropsychological case study of a patient with a mutation in the progranulin ("GRN") gene who presented with progressive word-finding difficulty. Key neuropsychological features in this case included gravely…

Uncovering Mental Representations with Markov Chain Monte Carlo

ERIC Educational Resources Information Center

Sanborn, Adam N.; Griffiths, Thomas L.; Shiffrin, Richard M.

2010-01-01

A key challenge for cognitive psychology is the investigation of mental representations, such as object categories, subjective probabilities, choice utilities, and memory traces. In many cases, these representations can be expressed as a non-negative function defined over a set of objects. We present a behavioral method for estimating these…

Mapping the Future: Young People and Career Guidance.

ERIC Educational Resources Information Center

St. John-Brooks, Caroline

This report examines the strengths and weaknesses of educational and career guidance in seven Organisation for Economic Development (OECD) countries. Chapter 1 defines educational and career guidance as embracing three key elements: educational, career, and personal/social guidance. Described in chapter 2 is the role of educational and career…

IMPLICATIONS OF USING ROBUST BAYESIAN ANALYSIS TO REPRESENT DIVERSE SOURCES OF UNCERTAINTY IN INTEGRATED ASSESSMENT

EPA Science Inventory

In our previous research, we showed that robust Bayesian methods can be used in environmental modeling to define a set of probability distributions for key parameters that captures the effects of expert disagreement, ambiguity, or ignorance. This entire set can then be update...

Redefining the Concept of Learning in Cooperative Extension

ERIC Educational Resources Information Center

Worker, Steven M.; Ouellette, Kristy L.; Maille, Alexa

2017-01-01

For Extension educational programs to meet the educational needs of today's youths, families, and communities, Extension needs to expand "what counts" as learning. The purpose of this article is to define learning in the context of Extension. We summarize key aspects of the educational research literature by comparing two prevailing…

Activity Theory and Ontology

ERIC Educational Resources Information Center

Peim, Nick

2009-01-01

This paper seeks to re-examine Yrio Engestrom's activity theory as a technology of knowledge designed to enable positive transformations of specific practices. The paper focuses on a key paper where Engestrom defines the nature and present state of activity theory. Beginning with a brief account of the relations between activity theory and…

The New Literacies of Online Reading Comprehension: Future Directions

ERIC Educational Resources Information Center

Coiro, Julie

2012-01-01

Research in four areas has the potential to dramatically improve how practitioners address the challenges of integrating digital texts and tasks into their literacy curriculum. Advances in defining and measuring key components of online reading comprehension are rapidly emerging. In addition, instructional models, such as Internet reciprocal…

Attitude Surveys Document Sampler.

ERIC Educational Resources Information Center

Walker, Albert, Comp.

This packet presents results of a series of attitude surveys representing a variety of purposes, methods and defined publics. They range from a simple questionnaire prepared and mailed to a small group of key individuals by a public relations staff to scientifically derived surveys purchased from Louis Harris and Associates and other research…

Deterrents to Women's Participation in Continuing Professional Development

ERIC Educational Resources Information Center

Chuang, Szu-Fang

2015-01-01

This study was designed to explore and define key factors that deter women from participating in continuing professional development (CPD) in the workplace. Four dimensions of deterrents that are caused by women's social roles, gender inequality and gender dimensions are discussed: family and time constraints, cost and work constraints, lack of…

Public Schools and the Common Good.

ERIC Educational Resources Information Center

Reese, William J.

1988-01-01

Improving public school education, especially for the poor, requires defining and articulating some vision of the common good. This article reviews key positions taken by liberals and conservatives regarding educational reform during the 19th and 20th centuries and critiques these positions with regard to their disservice to the poor. (IAH)

Pretreatment of woody biomass for biofuel production: energy efficiency, technologies, and recalcitrance

Treesearch

J.Y. Zhu; Xuejun Pan; Ronald S. Jr. Zalesny

2010-01-01

This mini review discusses several key technical issues associated with cellulosic ethanol production from woody biomass: energy consumption for woody biomass pretreatment, pretreatment energy efficiency, woody biomass pretreatment technologies, and quantification of woody biomass recalcitrance. Both total sugar yield and pretreatment energy efficiency, defined as the...

Missing School Matters

ERIC Educational Resources Information Center

Balfanz, Robert

2016-01-01

Results of a survey conducted by the Office for Civil Rights show that 6 million public school students (13%) are not attending school regularly. Chronic absenteeism--defined as missing more than 10% of school for any reason--has been negatively linked to many key academic outcomes. Evidence shows that students who exit chronic absentee status can…

Do Continuing Medical Education Articles Foster Shared Decision Making?

ERIC Educational Resources Information Center

Labrecque, Michel; Lafortune, Valerie; Lajeunesse, Judith; Lambert-Perrault, Anne-Marie; Manrique, Hermes; Blais, Johanne; Legare, France

2010-01-01

Introduction: Defined as reviews of clinical aspects of a specific health problem published in peer-reviewed and non-peer-reviewed medical journals, offered without charge, continuing medical education (CME) articles form a key strategy for translating knowledge into practice. This study assessed CME articles for mention of evidence-based…

Derivation of Habitat-Specific Dissolved Oxygen Criteria for Chesapeake Bay and its Tidal Tributaries

EPA Science Inventory

The Chesapeake 2000 Agreement committed its state and federal signatories to “define the water quality conditions necessary to protect aquatic living resources” in the Chesapeake Bay (USA) and its tidal tributaries. Hypoxia is one of the key water quality issues addressed as a re...

Solar Concepts: A Background Text.

ERIC Educational Resources Information Center

Gorham, Jonathan W.

This text is designed to provide teachers, students, and the general public with an overview of key solar energy concepts. Various energy terms are defined and explained. Basic thermodynamic laws are discussed. Alternative energy production is described in the context of the present energy situation. Described are the principal contemporary solar…

Financial Viability of Institutions. Issues in Post-Secondary Education.

ERIC Educational Resources Information Center

Jenny, Hans H.

Financial viability in postsecondary education is considered as part of the Postsecondary Education Core Design Project sponsored by the National Center for Education Statistics. Financial viability is defined within the scope of postsecondary education, and key policy issues at the national, state, and institutional levels are identified.…

Visualising Disability in the Past

ERIC Educational Resources Information Center

Devlieger, Patrick; Grosvenor, Ian; Simon, Frank; Van Hove, Geert; Vanobbergen, Bruno

2008-01-01

In recent years there has been a growth in interdisciplinary work which has argued that disability is not an isolated, individual medical pathology but instead a key defining social category like "race", class and gender. Seen in this way disability provides researchers with another analytic tool for exploring the nature of power. Running almost…

Forum Guide to Core Finance Data Elements. NFES 2007-801

ERIC Educational Resources Information Center

National Forum on Education Statistics, 2007

2007-01-01

This document provides an overview of key finance data terms and is designed to accompany the "Financial Accounting for Local and State School Systems: 2003 Edition" by identifying common reporting requirements and defining frequently used indicators and calculations using data elements from accounting and other data systems. It also…

The Retention and Attrition of Catholic School Principals

ERIC Educational Resources Information Center

Durow, W. Patrick; Brock, Barbara L.

2004-01-01

This article reports the results of a study of the retention of principals in Catholic elementary and secondary schools in one Midwestern diocese. Findings revealed that personal needs, career advancement, support from employer, and clearly defined role expectations were key factors in principals' retention decisions. A profile of components of…

What is information?†

PubMed Central

2016-01-01

Information is a precise concept that can be defined mathematically, but its relationship to what we call ‘knowledge’ is not always made clear. Furthermore, the concepts ‘entropy’ and ‘information’, while deeply related, are distinct and must be used with care, something that is not always achieved in the literature. In this elementary introduction, the concepts of entropy and information are laid out one by one, explained intuitively, but defined rigorously. I argue that a proper understanding of information in terms of prediction is key to a number of disciplines beyond engineering, such as physics and biology. PMID:26857663

Time series regression-based pairs trading in the Korean equities market

NASA Astrophysics Data System (ADS)

Kim, Saejoon; Heo, Jun

2017-07-01

Pairs trading is an instance of statistical arbitrage that relies on heavy quantitative data analysis to profit by capitalising low-risk trading opportunities provided by anomalies of related assets. A key element in pairs trading is the rule by which open and close trading triggers are defined. This paper investigates the use of time series regression to define the rule which has previously been identified with fixed threshold-based approaches. Empirical results indicate that our approach may yield significantly increased excess returns compared to ones obtained by previous approaches on large capitalisation stocks in the Korean equities market.

[Labor market structure and access to private health insurance in Brazil].

PubMed

Machado, Ana Flavia; Andrade, Mônica Viegas; Maia, Ana Carolina

2012-04-01

This paper aims to describe health insurance coverage among different types of workers in Brazil. Health insurance coverage and labor market insertion are used to define homogeneous groups of workers. The Grade of Membership method is used to build a typology of workers. The database was the Brazilian National Household Survey (PNAD) for 1998 and 2003, including a health survey. Five worker profiles were defined. The key variables were: health insurance coverage, schooling, and work status. The main findings show a positive association between health insurance coverage, income from work, and trade union membership.

Infrared thermal imaging figures of merit

NASA Technical Reports Server (NTRS)

Kaplan, Herbert

1989-01-01

Commercially available types of infrared thermal imaging instruments, both viewers (qualitative) and imagers (quantitative) are discussed. The various scanning methods by which thermal images (thermograms) are generated will be reviewed. The performance parameters (figures of merit) that define the quality of performance of infrared radiation thermometers will be introduced. A discussion of how these parameters are extended and adapted to define the performance of thermal imaging instruments will be provided. Finally, the significance of each of the key performance parameters of thermal imaging instruments will be reviewed and procedures currently used for testing to verify performance will be outlined.

An observational model for biomechanical assessment of sprint kayaking technique.

PubMed

McDonnell, Lisa K; Hume, Patria A; Nolte, Volker

2012-11-01

Sprint kayaking stroke phase descriptions for biomechanical analysis of technique vary among kayaking literature, with inconsistencies not conducive for the advancement of biomechanics applied service or research. We aimed to provide a consistent basis for the categorisation and analysis of sprint kayak technique by proposing a clear observational model. Electronic databases were searched using key words kayak, sprint, technique, and biomechanics, with 20 sources reviewed. Nine phase-defining positions were identified within the kayak literature and were divided into three distinct types based on how positions were defined: water-contact-defined positions, paddle-shaft-defined positions, and body-defined positions. Videos of elite paddlers from multiple camera views were reviewed to determine the visibility of positions used to define phases. The water-contact-defined positions of catch, immersion, extraction, and release were visible from multiple camera views, therefore were suitable for practical use by coaches and researchers. Using these positions, phases and sub-phases were created for a new observational model. We recommend that kayaking data should be reported using single strokes and described using two phases: water and aerial. For more detailed analysis without disrupting the basic two-phase model, a four-sub-phase model consisting of entry, pull, exit, and aerial sub-phases should be used.

Using advertisement light-panel and CMOS image sensor with frequency-shift-keying for visible light communication.

PubMed

Chow, Chi-Wai; Shiu, Ruei-Jie; Liu, Yen-Chun; Liao, Xin-Lan; Lin, Kun-Hsien; Wang, Yi-Chang; Chen, Yi-Yuan

2018-05-14

A frequency-shift-keying (FSK) visible light communication (VLC) system is proposed and demonstrated using advertisement light-panel as transmitter and mobile-phone image sensor as receiver. The developed application program (APP) in mobile-phone can retrieve the rolling shutter effect (RSE) pattern produced by the FSK VLC signal effectively. Here, we also define noise-ratio value (NRV) to evaluate the contrast of different advertisements displayed on the light-panel. Both mobile-phones under test can achieve success rate > 96% even when the transmission distance is up to 200 cm and the NRVs are low.

Upconversion-based receivers for quantum hacking-resistant quantum key distribution

NASA Astrophysics Data System (ADS)

Jain, Nitin; Kanter, Gregory S.

2016-07-01

We propose a novel upconversion (sum frequency generation)-based quantum-optical system design that can be employed as a receiver (Bob) in practical quantum key distribution systems. The pump governing the upconversion process is produced and utilized inside the physical receiver, making its access or control unrealistic for an external adversary (Eve). This pump facilitates several properties which permit Bob to define and control the modes that can participate in the quantum measurement. Furthermore, by manipulating and monitoring the characteristics of the pump pulses, Bob can detect a wide range of quantum hacking attacks launched by Eve.

Defining the conserved internal architecture of a protein kinase.

PubMed

Kornev, Alexandr P; Taylor, Susan S

2010-03-01

Protein kinases constitute a large protein family of important regulators in all eukaryotic cells. All of the protein kinases have a similar bilobal fold, and their key structural features have been well studied. However, the recent discovery of non-contiguous hydrophobic ensembles inside the protein kinase core shed new light on the internal organization of these molecules. Two hydrophobic "spines" traverse both lobes of the protein kinase molecule, providing a firm but flexible connection between its key elements. The spine model introduces a useful framework for analysis of intramolecular communications, molecular dynamics, and drug design. Published by Elsevier B.V.

Personalized Oncology in Interventional Radiology

PubMed Central

Abi-Jaoudeh, Nadine; Duffy, Austin G.; Greten, Tim F.; Kohn, Elise C.; Clark, Timothy W.I.; Wood, Bradford J.

2013-01-01

As personalized medicine becomes more applicable to oncologic practice, image-guided biopsies will be integral for enabling predictive and pharmacodynamic molecular pathology. Interventional radiology has a key role in defining patient-specific management. Advances in diagnostic techniques, genomics, and proteomics enable a window into subcellular mechanisms driving hyperproliferation, metastatic capabilities, and tumor angiogenesis. A new era of personalized medicine has evolved whereby clinical decisions are adjusted according to a patient’s molecular profile. Several mutations and key markers already have been introduced into standard oncologic practice. A broader understanding of personalized oncology will help interventionalists play a greater role in therapy selection and discovery. PMID:23885909

Dance between biology, mechanics, and structure: A systems-based approach to developing osteoarthritis prevention strategies.

PubMed

Chu, Constance R; Andriacchi, Thomas P

2015-07-01

Osteoarthritis (OA) is a leading cause of human suffering and disability for which disease-modifying treatments are lacking. OA occurs through complex and dynamic interplays between diverse factors over long periods of time. The traditional research and clinical focus on OA, the end stage disease, obscured understanding pathogenesis prior to reaching a common pathway defined by pain and functional deficits, joint deformity, and radiographic changes. To emphasize disease modification and prevention, we describe a multi-disciplinary systems-based approach encompassing biology, mechanics, and structure to define pre-osteoarthritic disease processes. Central to application of this model is the concept of "pre-osteoarthritis," conditions where clinical OA has not yet developed. Rather, joint homeostasis has been compromised and there are potentially reversible markers for heightened OA risk. Key messages from this perspective are (i) to focus research onto defining pre-OA through identifying and validating biological, mechanical, and imaging markers of OA risk, (ii) to emphasize multi-disciplinary approaches, and (iii) to propose that developing personalized interventions to address reversible markers of OA risk in healthy joints may be the key to prevention. Ultimately, a systems-based analysis of OA pathogenesis shows potential to transform clinical practice by facilitating development and testing of new strategies to prevent or delay the onset of osteoarthritis. © 2015 Orthopaedic Research Society. Published by Wiley Periodicals, Inc.

A design space exploration for control of Critical Quality Attributes of mAb.

PubMed

Bhatia, Hemlata; Read, Erik; Agarabi, Cyrus; Brorson, Kurt; Lute, Scott; Yoon, Seongkyu

2016-10-15

A unique "design space (DSp) exploration strategy," defined as a function of four key scenarios, was successfully integrated and validated to enhance the DSp building exercise, by increasing the accuracy of analyses and interpretation of processed data. The four key scenarios, defining the strategy, were based on cumulative analyses of individual models developed for the Critical Quality Attributes (23 Glycan Profiles) considered for the study. The analyses of the CQA estimates and model performances were interpreted as (1) Inside Specification/Significant Model (2) Inside Specification/Non-significant Model (3) Outside Specification/Significant Model (4) Outside Specification/Non-significant Model. Each scenario was defined and illustrated through individual models of CQA aligning the description. The R(2), Q(2), Model Validity and Model Reproducibility estimates of G2, G2FaGbGN, G0 and G2FaG2, respectively, signified the four scenarios stated above. Through further optimizations, including the estimation of Edge of Failure and Set Point Analysis, wider and accurate DSps were created for each scenario, establishing critical functional relationship between Critical Process Parameters (CPPs) and Critical Quality Attributes (CQAs). A DSp provides the optimal region for systematic evaluation, mechanistic understanding and refining of a QbD approach. DSp exploration strategy will aid the critical process of consistently and reproducibly achieving predefined quality of a product throughout its lifecycle. Copyright © 2016 Elsevier B.V. All rights reserved.

Emergency department operations dictionary: results of the second performance measures and benchmarking summit.

PubMed

Welch, Shari J; Stone-Griffith, Suzanne; Asplin, Brent; Davidson, Steven J; Augustine, James; Schuur, Jeremiah D

2011-05-01

The public, payers, hospitals, and Centers for Medicare and Medicaid Services (CMS) are demanding that emergency departments (EDs) measure and improve performance, but this cannot be done unless we define the terms used in ED operations. On February 24, 2010, 32 stakeholders from 13 professional organizations met in Salt Lake City, Utah, to standardize ED operations metrics and definitions, which are presented in this consensus paper. Emergency medicine (EM) experts attending the Second Performance Measures and Benchmarking Summit reviewed, expanded, and updated key definitions for ED operations. Prior to the meeting, participants were provided with the definitions created at the first summit in 2006 and relevant documents from other organizations and asked to identify gaps and limitations in the original work. Those responses were used to devise a plan to revise and update the definitions. At the summit, attendees discussed and debated key terminology, and workgroups were created to draft a more comprehensive document. These results have been crafted into two reference documents, one for metrics and the operations dictionary presented here. The ED Operations Dictionary defines ED spaces, processes, patient populations, and new ED roles. Common definitions of key terms will improve the ability to compare ED operations research and practice and provide a common language for frontline practitioners, managers, and researchers. © 2011 by the Society for Academic Emergency Medicine.

Scientific governance and the process for exposure scenario development in REACH.

PubMed

Money, Chris D; Van Hemmen, Joop J; Vermeire, Theo G

2007-12-01

The primary process established by the European Commission to address the science needed to define key REACH concepts and to help rationally implement REACH's ambitions is enshrined in a series of activities known as the REACH Implementation Projects (RIPs). These are projects that aim to define the methodology that could be used, and present the basis for guidance on the actual principles and procedures that may be (are proposed to be) followed in the development of the required documentation that ensures the safe use of chemicals. In order to develop soundly based and equitable regulation, it is necessary that science governance using established and accepted scientific principles must take a leading role. The extent to which such governance is embraced will be determined by many factors, but notably the process adopted to enable scientific discussion to take place. This article addresses the issues of science as they have impacted on the exemplification of the Exposure Scenario concept under REACH. The current RIP activities have created a non-adversarial process in which the key stakeholders are able to discuss the key REACH challenges. But the RIP activities will be finalised before REACH comes into force. A suitable mechanism should perhaps now be identified to ensure that this positive spirit of scientific discussion and collaboration can continue to benefit REACH and those that it serves well into the future.

Phased implementation of spaced clinic visits for stable HIV-positive patients in Rwanda to support Treat All.

PubMed

Nsanzimana, Sabin; Remera, Eric; Ribakare, Muhayimpundu; Burns, Tracy; Dludlu, Sibongile; Mills, Edward J; Condo, Jeanine; Bucher, Heiner C; Ford, Nathan

2017-07-21

In 2016, Rwanda implemented "Treat All," requiring the national HIV programme to increase antiretroviral (ART) treatment coverage to all people living with HIV. Approximately half of the 164,262 patients on ART have been on treatment for more than five years, and long-term retention of patients in care is an increasing concern. To address these challenges, the Ministry of Health has introduced a differentiated service delivery approach to reduce the frequency of clinical visits and medication dispensing for eligible patients. This article draws on key policy documents and the views of technical experts involved in policy development to describe the process of implementation of differentiated service delivery in Rwanda. Implementation of differentiated service delivery followed a phased approach to ensure that all steps are clearly defined and agreed by all partners. Key steps included: definition of scope, including defining which patients were eligible for transition to the new model; definition of the key model components; preparation for patient enrolment; considerations for special patient groups; engagement of implementing partners; securing political and financial support; forecasting drug supply; revision, dissemination and implementation of ART guidelines; and monitoring and evaluation. Based on the outcomes of the evaluation of the new service delivery model, the Ministry of Health will review and strategically reduce costs to the national HIV program and to the patient by exploring and implementing adjustments to the service delivery model.

Optimizing Requirements Decisions with KEYS

NASA Technical Reports Server (NTRS)

Jalali, Omid; Menzies, Tim; Feather, Martin

2008-01-01

Recent work with NASA's Jet Propulsion Laboratory has allowed for external access to five of JPL's real-world requirements models, anonymized to conceal proprietary information, but retaining their computational nature. Experimentation with these models, reported herein, demonstrates a dramatic speedup in the computations performed on them. These models have a well defined goal: select mitigations that retire risks which, in turn, increases the number of attainable requirements. Such a non-linear optimization is a well-studied problem. However identification of not only (a) the optimal solution(s) but also (b) the key factors leading to them is less well studied. Our technique, called KEYS, shows a rapid way of simultaneously identifying the solutions and their key factors. KEYS improves on prior work by several orders of magnitude. Prior experiments with simulated annealing or treatment learning took tens of minutes to hours to terminate. KEYS runs much faster than that; e.g for one model, KEYS ran 13,000 times faster than treatment learning (40 minutes versus 0.18 seconds). Processing these JPL models is a non-linear optimization problem: the fewest mitigations must be selected while achieving the most requirements. Non-linear optimization is a well studied problem. With this paper, we challenge other members of the PROMISE community to improve on our results with other techniques.

Approaches to ensuring and improving quality in the context of health system strengthening: a cross-site analysis of the five African Health Initiative Partnership programs

PubMed Central

2013-01-01

Background Integrated into the work in health systems strengthening (HSS) is a growing focus on the importance of ensuring quality of the services delivered and systems which support them. Understanding how to define and measure quality in the different key World Health Organization building blocks is critical to providing the information needed to address gaps and identify models for replication. Description of approaches We describe the approaches to defining and improving quality across the five country programs funded through the Doris Duke Charitable Foundation African Health Initiative. While each program has independently developed and implemented country-specific approaches to strengthening health systems, they all included quality of services and systems as a core principle. We describe the differences and similarities across the programs in defining and improving quality as an embedded process essential for HSS to achieve the goal of improved population health. The programs measured quality across most or all of the six WHO building blocks, with specific areas of overlap in improving quality falling into four main categories: 1) defining and measuring quality; 2) ensuring data quality, and building capacity for data use for decision making and response to quality measurements; 3) strengthened supportive supervision and/or mentoring; and 4) operational research to understand the factors associated with observed variation in quality. Conclusions Learning the value and challenges of these approaches to measuring and improving quality across the key components of HSS as the projects continue their work will help inform similar efforts both now and in the future to ensure quality across the critical components of a health system and the impact on population health. PMID:23819662

Using a Delphi process to define priorities for prison health research in Canada

PubMed Central

Kouyoumdjian, Fiona G; Schuler, Andrée; McIsaac, Kathryn E; Pivnick, Lucie; Matheson, Flora I; Brown, Glenn; Kiefer, Lori; Silva, Diego; Hwang, Stephen W

2016-01-01

Objectives A large number of Canadians spend time in correctional facilities each year, and they are likely to have poor health compared to the general population. Relatively little health research has been conducted in Canada with a focus on people who experience detention or incarceration. We aimed to conduct a Delphi process with key stakeholders to define priorities for research in prison health in Canada for the next 10 years. Setting We conducted a Delphi process using an online survey with two rounds in 2014 and 2015. Participants We invited key stakeholders in prison health research in Canada to participate, which we defined as persons who had published research on prison health in Canada since 1994 and persons in the investigators’ professional networks. We invited 143 persons to participate in the first round and 59 participated. We invited 137 persons to participate in the second round and 67 participated. Primary and secondary outcome measures Participants suggested topics in the first round, and these topics were collated by investigators. We measured the level of agreement among participants that each collated topic was a priority for prison health research in Canada for the next 10 years, and defined priorities based on the level of agreement. Results In the first round, participants suggested 71 topics. In the second round, consensus was achieved that a large number of suggested topics were research priorities. Top priorities were diversion and alternatives to incarceration, social and community re-integration, creating healthy environments in prisons, healthcare in custody, continuity of healthcare, substance use disorders and the health of Aboriginal persons in custody. Conclusions Generated in an inclusive and systematic process, these findings should inform future research efforts to improve the health and healthcare of people who experience detention and incarceration in Canada. PMID:26769790

Over Ten Million Served: Gendered Service in Language and Literature Workplaces

ERIC Educational Resources Information Center

Masse, Michelle A., Ed.; Hogan, Katie J., Ed.

2010-01-01

All tenured and tenure-track faculty know the trinity of promotion and tenure criteria: research, teaching, and service. While teaching and research are relatively well-defined areas of institutional focus and evaluation, service work is rarely tabulated or analyzed as a key aspect of higher education's political economy. Instead, service, silent…

Environmental Values related to fish and wildlife lands

Treesearch

David N. Bengston

2000-01-01

THe purpose of this paper is to provide an overview of key concepts related to environmental values and their importance for public land managers. The following section defines environmental values and discusses their relationship to environmnetal attitudes and beliefs. This is followed by presentation of a broad system for classifying environmental values and...

Art Rocks!

ERIC Educational Resources Information Center

Chapin, Erika

2008-01-01

Though people may like different types of music, everyone likes music. In middle school, music and art are of key importance for students to express and define what kind of person they are. In this article, the author presents an art project where students are asked to create their own guitars. (Contains 1 resource and 3 online resources.)

Three Waves of International Student Mobility (1999-2020)

ERIC Educational Resources Information Center

Choudaha, Rahul

2017-01-01

This article analyses the changes in international student mobility from the lens of three overlapping waves spread over seven years between 1999 and 2020. Here a wave is defined by the key events and trends impacting international student mobility within temporal periods. Wave I was shaped by the terrorist attacks of 2001 and enrolment of…

Mentoring in Business and Industry: The Need for a Phenomenological Perspective

ERIC Educational Resources Information Center

Gibson, Sharon K.

2004-01-01

Determining the potential benefits of mentoring is confounded by the lack of clarity surrounding the definition of mentoring in business and industry. Key dimensions of mentoring that are affected by the way in which mentoring is defined are explored, including prevalence, outcomes, gender and formal/informal relationships. This definitional…

Multidatabase Query Processing with Uncertainty in Global Keys and Attribute Values.

ERIC Educational Resources Information Center

Scheuermann, Peter; Li, Wen-Syan; Clifton, Chris

1998-01-01

Presents an approach for dynamic database integration and query processing in the absence of information about attribute correspondences and global IDs. Defines different types of equivalence conditions for the construction of global IDs. Proposes a strategy based on ranked role-sets that makes use of an automated semantic integration procedure…

Total Quality Management in Education. Second Edition.

ERIC Educational Resources Information Center

Sallis, Edward

Quality is at the top of most agendas, and improving quality is probably the most important task facing any institution. In addition, quality is difficult to define or measure. This book, the second edition of "Total Quality Management in Education," introduces the key concepts of Total Quality Management (TQM) and demonstrates how they…

Evaluation of whole mount in situ hybridization as a tool for pathway-based toxicological research in early-life stage fathead minnows

EPA Science Inventory

Early-life stage fish can be more sensitive to chemical exposure than mature, adult fish. Therefore, defining adverse outcome pathways (AOPs) relevant to early-life stages is critical for linking perturbations of key events during fish development to potential adverse outcomes of...

Atypical Neural Self-Representation in Autism

ERIC Educational Resources Information Center

Lombardo, Michael V.; Chakrabarti, Bhismadev; Bullmore, Edward T.; Sadek, Susan A.; Pasco, Greg; Wheelwright, Sally J.; Suckling, John; Baron-Cohen, Simon

2010-01-01

The "self" is a complex multidimensional construct deeply embedded and in many ways defined by our relations with the social world. Individuals with autism are impaired in both self-referential and other-referential social cognitive processing. Atypical neural representation of the self may be a key to understanding the nature of such impairments.…

77 FR 66915 - Amendment of Prohibited Payment Option Under Single-Employer Defined Benefit Plan of Plan Sponsor...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-08

... contains regulatory documents #0;having general applicability and legal effect, most of which are keyed #0.... These regulations affect administrators, employers, participants, and beneficiaries of such a plan... of the monthly amount paid under a single life annuity (plus any social security supplements...

Driving Change: The Role of "Emotional Connectedness"--A Case Study

ERIC Educational Resources Information Center

Lacoste, Sylvie M.; Dekker, Janet

2016-01-01

Purpose: The purpose of this paper is to understand which change process the supplying organization should define for its customer-facing organization in order to successfully increase customer orientation and to be on the short list of their customers' key suppliers. Design/methodology/approach: Action research was used to carry out this…

Relationships and Reciprocality in Student and Academic Services

ERIC Educational Resources Information Center

Small, Kate

2008-01-01

As part of the "face" a university projects to the world, student service staff play a key role in constructing an institution's external identity. Yet, there have been few studies of who are the general staff providing these services, and how they define their role within their institutions. Although there have been several excellent studies…

Final report for the National Center for Intermodal Transportation for Economic Competitiveness : project title: student technology exchange program (STEP) for engineering/robotics in middle school students.

DOT National Transportation Integrated Search

2015-05-05

Key outcomes or other achievements - This project highlighted the importance of math and science concepts within three of the six STEM-related career clusters as defined by the Mississippi Department of Education: Agriculture, Food and Natural Resour...

Cycle Commuting and Perceptions of Barriers: Stages of Change, Gender and Occupation

ERIC Educational Resources Information Center

van Bekkum, Jennifer E.; Williams, Joanne M.; Morris, Paul Graham

2011-01-01

Purpose: The aim of this study is to investigate perceptions of cycle commuting barriers in relation to stage of change, gender and occupational role. Stage of change is a key construct of the transtheoretical model of behaviour change that defines behavioural readiness (intentions and actions) into five distinct categories.…

Informing Food Protection Education: A Project to Define and Classify Resources for a Cross-Disciplinary Expert Community

ERIC Educational Resources Information Center

Schenck-Hamlin, Donna; Pierquet, Jennifer; McClellan, Chuck

2011-01-01

In the wake of the September 2001 attacks, the U.S. government founded the Department of Homeland Security (DHS) with responsibility to develop a National Infrastructure Protection Plan for securing critical infrastructures and key resources. DHS established interdisciplinary networks of academic expertise administered through Centers of…

A Framework to Support Research on Informal Inferential Reasoning

ERIC Educational Resources Information Center

Zieffler, Andrew; Garfield, Joan; delMas, Robert; Reading, Chris

2008-01-01

Informal inferential reasoning is a relatively recent concept in the research literature. Several research studies have defined this type of cognitive process in slightly different ways. In this paper, a working definition of informal inferential reasoning based on an analysis of the key aspects of statistical inference, and on research from…

Engineering Education: A Clear Decision

ERIC Educational Resources Information Center

Strimel, Greg J.; Grubbs, Michael E.; Wells, John G.

2017-01-01

The core subjects in P-12 education have a common key characteristic that makes them stable over time. That characteristic is a steady content. For example, in the sciences, the basics of biology remain the same--the cell is the basic building block around which organisms are defined, characterized, structured, etc. Similarly, the basics of…

Triple Helix Systems: An Analytical Framework for Innovation Policy and Practice in the Knowledge Society

ERIC Educational Resources Information Center

Ranga, Marina; Etzkowitz, Henry

2013-01-01

This paper introduces the concept of Triple Helix systems as an analytical construct that synthesizes the key features of university--industry--government (Triple Helix) interactions into an "innovation system" format, defined according to systems theory as a set of components, relationships and functions. Among the components of Triple…

Reader Theories and Educational Media Analysis.

ERIC Educational Resources Information Center

Becker, Ann DeVaney

Post structural reader theories--i.e., theories that focus on the reader/viewer rather than the text as the creator of meaning--are considered in this paper in terms of their application to educational media research. Some key concepts of reader theories are defined as follows: (1) reading is the process of creating meaning while viewing an…

Beyond Description and Prescription: Towards Conducive Assessment in Social Work Education

ERIC Educational Resources Information Center

Cooper, Barry; Broadfoot, Patricia

2006-01-01

The latent power of social work's position at the centre of welfare services and as a coordinator and definer of social realities can be argued to have led social work to become "the assessment profession". Building upon a critique of the key distinction between "description and prescription", we argue that the…

The Importance of the Source of Power in an Educational Setting.

ERIC Educational Resources Information Center

Golanda, Eugene L.

This paper raises important questions about proposals for empowerment and shared governance in U.S. schools. Holding that consent is the key to understanding power and empowerment, the paper defines these concepts, discusses the purposes of empowerment, describes the types of empowerment being attempted, and outlines some predictable consequences.…

Initial Teacher Education in Russia: Connecting Theory, Practice and Research

ERIC Educational Resources Information Center

Valeeva, Roza A.; Gafurov, Ilshat R.

2017-01-01

This paper explores initial teacher education (ITE) in Russia, its organisation and content in the light of international literature. Changes in the political, socio-economic and cultural life of Russia in recent decades have defined a completely different model of teacher education. This model has evolved through key policy documents including…

Annual Research Review: Conceptualising Functional Impairment in Children and Adolescents

ERIC Educational Resources Information Center

Rapee, Ronald M.; Bogels, Susan M.; van der Sluis, Cathy M.; Craske, Michelle G.; Ollendick, Thomas

2012-01-01

Functional impairment is a key factor in the clinical importance of mental health problems in children. Yet, the nature of impairment and criteria for defining and assessing impairment in childhood disorders has been surprisingly overlooked in much of the literature. The current article examines the extant literature on the conceptualisation,…

Defining Teacher Leadership: Affirming the Teacher Leader Model Standards

ERIC Educational Resources Information Center

Cosenza, Michael N.

2015-01-01

Although there is no common definition for teacher leadership, the concept is continually advanced as a key component for both the success of schools and the professionalization of teachers (Boles & Troen, 1994; Dozier, 2007; Greenlee, 2007; Lieberman, 1987; Smith, 1999). Teachers need to be given opportunities to leave the isolation of their…

The English or Foreign Language Major and Liberal Education

ERIC Educational Resources Information Center

Liberal Education, 2009

2009-01-01

Study in language, literature, and culture has long been a defining feature of education in the liberal arts. Speaking, reading, and writing have traditionally stood at the heart of education because the arts of language and the tools of literacy are key qualifications for full participation in social, political, economic, and cultural life. Today…

On Reflection: Is Reflexivity Necessarily Beneficial in Intercultural Education?

ERIC Educational Resources Information Center

Blasco, Maribel

2012-01-01

This article explores how the concept of reflexivity is used in intercultural education. Reflexivity is often presented as a key learning goal in acquiring intercultural competence (ICC). Yet, reflexivity can be defined in different ways, and take different forms across time and space, depending on the concepts of selfhood that prevail and how…

Drinker Identity: Key Risk Factor for Adolescent Alcohol Use

ERIC Educational Resources Information Center

Lee, Chia-Kuei; Corte, Colleen; Stein, Karen F.

2018-01-01

Background: Adolescent alcohol use continues to be a critical public health problem with both short- and long-term negative health consequences. Defining oneself in terms of alcohol, a drinking-related identity, has been shown to predict high levels of alcohol use. Because adolescence is the developmental period during which identity development…

Understanding Curriculum Change in an ELT School in Greece

ERIC Educational Resources Information Center

Kostoulas, Achilleas; Stelma, Juup

2017-01-01

This article reports on a case study of a language school in Greece, with a view to putting forward an understanding of the drivers that sustain or delay curricular innovation. Key to this understanding is the construct of intentionality, defined as "purposes" that drive teaching and learning activity. In the article, we describe three…

10 CFR 75.4 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 274b. of the Act. Batch means a portion of nuclear material handled as a unit for accounting purposes at a key measurement point and for which the composition and quantity are defined by a single set of specifications or measurements. The nuclear material may be in bulk form or contained in a number of separate...

A Wiki Collaboration to Create National Guidelines: Tips for Professional Practice

ERIC Educational Resources Information Center

Moser, Patt

2009-01-01

In 2006, technology directors from independent schools across the country had banded together and created "Principles of Good Practice" for technology in independent schools. These principles "define high standards and ethical behavior in key areas of independent school operations" (NAIS 2006). This author decided that it was time for the National…

Same-Sex Couples: Legal Complexities

ERIC Educational Resources Information Center

Oswald, Ramona Faith; Kuvalanka, Katherine A.

2008-01-01

In this article, the authors present a typology for organizing our current knowledge regarding same-sex couples in the United States who have and have not established legal ties between partners. This framework is complemented by a discussion of key rulings that define what is legally possible as well as the introduction of "legal consciousness,"…

Social Responsibility in Advertising: A Marketing Communications Student Perspective

ERIC Educational Resources Information Center

Kendrick, Alice; Fullerton, Jami A.; Kim, Yeo Jung

2013-01-01

Although advertising has played a key role in bringing corporate social responsibility (CSR) to the public agenda on behalf of agency clients, little effort has been made to define what social responsibility means in advertising. A national survey of 1,045 advertising and marketing communications students from 176 colleges and universities were…

Building Expertise to Support Digital Scholarship: A Global Perspective

ERIC Educational Resources Information Center

Lewis, Vivian; Spiro, Lisa; Wang, Xuemao; Cawthorne, Jon E.

2015-01-01

This report sheds light on the expertise required to support a robust and sustainable digital scholarship (DS) program. It focuses first on defining and describing the key domain knowledge, skills, competencies, and mindsets at some of the world's most prominent digital scholarship programs. It then identifies the main strategies used to build…

Which Emotional Profiles Exhibit the Best Learning Outcomes? A Person-Centered Analysis of Students' Academic Emotions

ERIC Educational Resources Information Center

Ganotice, Fraide A., Jr.; Datu, Jesus Alfonso D.; King, Ronnel B.

2016-01-01

Previous studies on academic emotions have mostly used variable-centered approaches. Although these studies have elucidated the relationships between academic emotions and key academic outcomes, they cannot identify naturally-occurring groups of students defined by distinct academic emotion profiles. In this study, we adopted a person-centered…

Career Education for Elementary Grades.

ERIC Educational Resources Information Center

Dianna, Michael A.

Information and activities are provided to help elementary school teachers develop a career education "environment" for children. Ten basic premises of career education are outlined, and the key ideas and terms that emerge from the premises are defined. The eight goals of career education are set forth to provide the teacher with a base from which…

Development and characterization of mouse monoclonal antibodies reactive with chicken IL-8

USDA-ARS?s Scientific Manuscript database

Interleukin-8 (IL-8) is a key mediator in neutrophil-mediated acute proinflammatory response and activates multiple signaling pathways downstream of two receptors (CXCR1 and CXCR2). However, there have not been any monoclonal antibodies which specifically detect chicken IL8 (chIL8) and define its b...

Social Participation and Friendship Quality of Students with Special Educational Needs in Regular Greek Primary Schools

ERIC Educational Resources Information Center

Avramidis, Elias; Avgeri, Georgia; Strogilos, Vasilis

2018-01-01

The study addresses the social participation of integrated students with special educational needs (SEN) in upper primary regular classes in Greece alongside their perceptions of best friend quality. Social participation was defined as consisting of four key dimensions: students' acceptance by classmates, friendships, social self-perceptions, and…

How Sociological Leaders Teach: Some Key Principles

ERIC Educational Resources Information Center

Persell, Caroline Hodges; Pfeiffer, Kathryn M.; Syed, Ali

2008-01-01

This paper arose from a larger study designed to explore what leaders in the field of sociology think are the most important goals and principles for students to understand after taking a college-level introductory course and how they teach those principles. A population of scholarly leaders in sociology was defined by various forms of peer…

The Role of Communication in Library Management. Occasional Paper No. 34.

ERIC Educational Resources Information Center

Mwenegoha, Hamza A.

This paper defines and discusses the nature of management; outlines the primary management functions and activities, emphasizing the importance of communication and coordination to successful management; and examines the place of communication as a management function in the library setting. After a discussion of the key role of coordination in…

The Influence of the Knowledge Society: Trends in Adult Higher Education

ERIC Educational Resources Information Center

Kasworm, Carol

2011-01-01

Current understandings of a knowledge economy have been emerging from two defining forces: the rise in quality and intensity of knowledge as a key commodity for economic development and the increasing globalization through information technology of both knowledge exchange and economic activities. The future of adult higher education is focused on…

Immigrant Youth in Canadian Health Promoting Schools: A Literature Review

ERIC Educational Resources Information Center

Nyika, Lawrence; McPherson, Charmaine; Murray-Orr, Anne

2017-01-01

In this essay, we review empirical, theoretical, and substantial grey literature in relation to immigrant youth and health promoting schools (HPS). We examine the health promotion concept to consider how it may inform the HPS model. Using Canada as an example, we examine current immigrant youth demographics and define several key terms including…

Estimating and validating harvesting system production through computer simulation

Treesearch

John E. Baumgras; Curt C. Hassler; Chris B. LeDoux

1993-01-01

A Ground Based Harvesting System Simulation model (GB-SIM) has been developed to estimate stump-to-truck production rates and multiproduct yields for conventional ground-based timber harvesting systems in Appalachian hardwood stands. Simulation results reflect inputs that define harvest site and timber stand attributes, wood utilization options, and key attributes of...

More than attendance: the importance of after-school program quality.

PubMed

Hirsch, Barton J; Mekinda, Megan A; Stawicki, Julieann

2010-06-01

A central theme of the articles featured in this issue is the need to improve the quality of after-school programs. In this commentary, we discuss why student engagement, program characteristics and implementation, staff training, and citywide policy are key considerations in the effort to define and achieve high quality programs for youth.

Health Literacy Competencies: Using Q Methodology to Assess the Perceptions of Health Care Professionals

ERIC Educational Resources Information Center

Rogers, Russet Rena

2016-01-01

This research study investigated the perceptions of health care professionals regarding a newly defined set of health literacy competencies. A key step in the development of professional competency statements is to solicit the opinions and feedback of individuals currently practicing or working within the appropriate setting. Health literacy and…

Scientific and Regulatory Policy Committee (SRPC) Review: Interpretation and Use of Cell Proliferation Data in Cancer Risk Assessment

EPA Science Inventory

Increased cell proliferation is a defining feature of carcinogenesis and a central key event in the mode of action for many non-genotoxic carcinogens. Quantitative cell proliferation data thus play an important role in the safety assessment of many pharmaceutical and environment...

Quality Guidance: A Sectoral Analysis. NICEC Project Report.

ERIC Educational Resources Information Center

Watts, A. G.; Sadler, Jackie

This report reviews the structure of the guidance field and provides a sector-by-sector analysis of current quality assurance arrangements in the United Kingdom. Part 1 presents an outline of the guidance sector, including some key concepts, structures, and roles. It defines guidance and other terms; discusses the three main categories…

Time Poverty Thresholds and Rates for the US Population

ERIC Educational Resources Information Center

Kalenkoski, Charlene M.; Hamrick, Karen S.; Andrews, Margaret

2011-01-01

Time constraints, like money constraints, affect Americans' well-being. This paper defines what it means to be time poor based on the concepts of necessary and committed time and presents time poverty thresholds and rates for the US population and certain subgroups. Multivariate regression techniques are used to identify the key variables…

Integration of Computers in Education: A Curriculum Perspective.

ERIC Educational Resources Information Center

Plomp, Tjeerd

This discussion of a major problem area in education--the curricular and implementation aspects of the application of the computer or new information technologies--focuses first on the use and integration of computers in existing courses or subjects in the curriculum, and defines some key terms. The next section considers issues in the…

International Organisations and the Evaluation of Education Systems: A Critical Comparative Analysis

ERIC Educational Resources Information Center

Neves, Claudia

2008-01-01

This article seeks to develop research involving a macro-level critical comparative analysis of reference documents produced by international organisations (UNDP, OECD, UNESCO, the World Bank and the European Union) which guide world education policy decisions. The primary objective was to consider the key guidelines currently defined for…

Grassland and shrubland habitat types of western Montana

Treesearch

W. F. Mueggler; W. L. Stewart

1978-01-01

A classification system based upon potential natural vegetation is presented for the grasslands and shrublands of the mountainous western third of Montana. The classification was developed by analyzing data from 580 stands. Twenty-nine habitat types in 13 climax series are defined and a diagnostic key provided for field identification. Environment, vegetative...

Active Learning: Positive Impact for Schools and Democratic Society.

ERIC Educational Resources Information Center

Powell, Larry E.

The concept of active learning is analyzed in terms of its place in the democratic school. Defined is the meaning of an effective democracy and active learning. The relationship of participation to democracy is analyzed in terms of effectiveness. Ownership and empowerment are the keys to participatory democracy. Several educators' philosophies are…

Multidimensional Approach to Detecting Creative Potential in Managers

ERIC Educational Resources Information Center

Caroff, Xavier; Lubart, Todd

2012-01-01

Creativity is increasingly recognized as a key component to success in the workplace. This article explores the detection of creative potential in managers. In a first part, creative potential is defined and a multivariate approach concerning the psychological resources for creativity is presented. Then, in a second part, an application of this…

Complicity or Multiplicity? Defining Boundaries for Graduate Teaching Assistant Success

ERIC Educational Resources Information Center

Dunn-Haley, Karen; Zanzucchi, Anne

2012-01-01

Professional development of graduate teaching assistants (GTAs) regarding interpersonal boundaries is key not only to the well-being of the GTAs but also to the undergraduates they are teaching. GTAs who are developing their professional identities are a primary contact for undergraduates, especially in lower-division classes, and thus play a key…

Academic Advising: Organizing and Delivering Services for Student Success. New Directions for Community Colleges, Number 82.

ERIC Educational Resources Information Center

King, Margaret C., Ed.

1993-01-01

Offering new perspectives on academic advising in community colleges, this book defines developmental academic advising, describes the organization and delivery of advising services, and discusses key components of effective programs. The following 10 chapters are included: (1) "Developmental Academic Advising," by Thaddeus M. Raushi,…

The Effect of Key on Vocal Sight-Reading Achievement

ERIC Educational Resources Information Center

Henry, Michele L.

2013-01-01

At its most basic level, sight-reading can be defined as the production of accurate pitch and rhythm from a previously unseen musical score. For vocalists, sight-reading principally involves the production of pitches by determining their relationship within a tonal framework. The ability to mentally conceive tonal function and convert it into…

NHEXAS PHASE I ARIZONA STUDY--STANDARD OPERATING PROCEDURE FOR CODING: BASELINE QUESTIONNAIRE (HOUSEHOLD) (UA-D-7.0)

EPA Science Inventory

The purpose of this SOP is to define the coding strategy for the Baseline Questionnaire. This questionnaire was developed for use in the Arizona NHEXAS project and the "Border" study. Household and individual data were combined in a single Baseline Questionnaire data file. Key...

Can interpreting sediment toxicity tests a mega sites benefit from novel approaches to normalization to address batching of tests?

EPA Science Inventory

Sediment toxicity tests are a key tool used in Ecological Risk Assessments for contaminated sediment sites. Interpreting test results and defining toxicity is often a challenge. This is particularly true at mega sites where the testing regime is large, and by necessity performed ...

Articulation and Transfer: How Successful Is It in Missouri and Maryland?

ERIC Educational Resources Information Center

Goff, Donald Gary

This report examines the articulation and transfer policies of Maryland and Missouri and reviews the extent to which these guidelines provide for a seamless transition between community colleges and state universities. The author begins by defining the key concepts relevant to this study (e.g., transfer, articulation, native student, transfer…

Attracting and Retaining Teachers: A Question of Motivation

ERIC Educational Resources Information Center

Muller, Karin; Alliata, Roberta; Benninghoff, Fabienne

2009-01-01

Attracting and retaining competent teachers is a key concern when it comes to managing the supply and demand for teachers. This article examines the motivation that prompts people to enter or leave the teaching profession with the aim of identifying a decision framework for defining teacher policies. The results are based on the teacher workforce…

Leisure Counselling, Coping Skills and Therapeutic Applications

ERIC Educational Resources Information Center

Juniper, Dean

2005-01-01

Leisure counselling is defined as the systematic exploitation of a client's past, existing or prospective hobbies, activities and interests for broad psychotherapeutic purposes. It functions as a powerful agent in the invigoration of a range of existing but inadequate coping skills, and can also act in an innovatory style when such key skills are…

From Moral Exclusion to Moral Inclusion: Theory for Teaching Peace

ERIC Educational Resources Information Center

Opotow, Susan; Gerson, Janet; Woodside, Sarah

2005-01-01

This article presents Moral Exclusion Theory as a way to systematize the study of complex issues in peace education and to challenge the thinking that supports oppressive social structures. The authors define its 2 key concepts: moral exclusion, the limited applicability of justice underlying destructive conflicts and difficult social problems;…

Enhancing Self-Efficacy of Elementary School Students to Learn Mathematics

ERIC Educational Resources Information Center

Katz, Sara

2015-01-01

Mathematics is a key to all scientific subjects. Learning mathematics requires cognitive and meta-cognitive effort. Many students suffer from mathematics anxiety that very often leads to physiological symptoms. Self-efficacy is defined as people's beliefs about their capabilities to produce designated levels of performance that affect their lives.…

Interactivity Between Proteges and Scientists in an Electronic Mentoring Program

ERIC Educational Resources Information Center

Bonnett, Cara; Wildemuth, Barbara M.; Sonnenwald, Diane H.

2006-01-01

Interactivity is defined by Henri (1992) as a three-step process involving communication of information, a response to this information, and a reply to that first response. It is a key dimension of computer-mediated communication, particularly in the one-on-one communication involved in an electronic mentoring program. This report analyzes the…

Developing a Template for National Child Protection Index Reports

ERIC Educational Resources Information Center

Ager, Alastair; Stark, Lindsay; Chu, Erin; Dewan, Shweta; Boothby, Neil

2011-01-01

Objectives: What impact does the strengthening of child rights have on the experience and circumstances of children? CRC General Comment 13 emphasizes that defining measurable targets for improvements in child protection is a key element of efforts to strengthen child rights and well-being across the world. This paper describes an attempt to…

Military Cultural Competency: Understanding How to Serve Those Who Serve

ERIC Educational Resources Information Center

Bonura, Kimberlee Bethany; Lovald, Nicole

2015-01-01

The aim of this essay is to define and describe the different constituents of the military population, and present the challenges this demographic faces when pursuing higher education. The essay also discusses key aspects higher education professionals must understand in order to better serve military populations, such as federal regulations and…

Civics Education for Adult English Language Learners. ERIC Q & A.

ERIC Educational Resources Information Center

Terrill, Lynda

This article provides a brief historical review of efforts to prepare immigrants to pass the U.S. citizenship test, defines key terms, discusses events that have shaped civics education, and offers suggestions, whatever the approach chosen, for integrating civics content with English-as-a-Second-Language (ESL) skills development. Covered topics…

The Key Factors Affecting Students' Individual Interest in School Science Lessons

ERIC Educational Resources Information Center

Cheung, Derek

2018-01-01

Individual interest in school science lessons can be defined as a relatively stable and enduring personal emotion comprising affective and behavioural reactions to events in the regular science lessons at school. Little research has compared the importance of different factors affecting students' individual interest in school science lessons. The…

Articulating Performance Expectations for Scholarship at an Australian Regional University

ERIC Educational Resources Information Center

Crookes, Patrick A.; Smith, Kylie M.; Else, Fabienne C.; Crookes, Ellie

2016-01-01

With an academic workforce undergoing transformation, it is vital that universities rethink how they define and value scholarship through their processes for academic promotion. A key part of this rethink is to review and refine existing documentation about promotion to reflect changing conceptions of scholarly work, in a way that enables scholars…

The Institution as a Citizen: How Colleges and Universities Enhance Their Civic Roles. Working Paper.

ERIC Educational Resources Information Center

Thomas, Nancy L.

This paper considers how colleges and universities can best fulfill the commitment of service to external communities, broadly defined to include local, national, and international concerns. Data come from interviews with key institutional representatives. The first section of the paper offers specific examples of how various colleges and…

A Review of Defining and Measuring Sociability in Children with Intellectual Disabilities

ERIC Educational Resources Information Center

Cook, Fay; Oliver, Chris

2011-01-01

There is a substantial body of research indicating that compromised social functioning for individuals with intellectual disabilities has far reaching implications for quality of life, community participation and wellbeing. However, an inherent difficulty for research into social functioning is the lack of agreed definition of key concepts in the…

Media Literacy: The School Library Media Center's New Curriculum Baby.

ERIC Educational Resources Information Center

Robinson, Julia

1994-01-01

Defines seven key concepts of media literacy education. Discusses reading visual media as well as print media and computer programs; determining values and ethics; decoding or deconstructing; critical thinking; the promotion of media literacy by interest groups; and educational restructuring with the role of the school library media specialist as…

Development of a Computer-Based Measure of Listening Comprehension of Science Talk

ERIC Educational Resources Information Center

Lin, Sheau-Wen; Liu, Yu; Chen, Shin-Feng; Wang, Jing-Ru; Kao, Huey-Lien

2015-01-01

The purpose of this study was to develop a computer-based assessment for elementary school students' listening comprehension of science talk within an inquiry-oriented environment. The development procedure had 3 steps: a literature review to define the framework of the test, collecting and identifying key constructs of science talk, and…

Using Students' Performance to Improve Ontologies for Intelligent E-Learning System

ERIC Educational Resources Information Center

Icoz, Kutay; Sanalan, Vehbi A.; Ozdemir, Esra Benli; Kaya, Sukru; Cakar, Mehmet Akif

2015-01-01

Ontologies have often been recommended for E-learning systems, but few efforts have successfully incorporated student data to represent knowledge conceptualizations. Defining key concepts and their relations between each other establishes the backbone of our E-learning system. The system guides an individual student through his/her course by…

NATO’s Global Role: To What Extent Will NATO Pursue a Global Orientation

DTIC Science & Technology

2004-03-01

introversion and fragmentation. Above all, the most essential issue was noted by Joschka Fisher: “NATO will remain one of the key cornerstones for peace and...The commitment of adequate resources is fundamental to improving capabilities. However, the defined threshold of 2% of GDP devoted to defense, as one

Modular System to Enable Extravehicular Activity

NASA Technical Reports Server (NTRS)

Sargusingh, Miriam J.

2011-01-01

The ability to perform extravehicular activity (EVA), both human and robotic, has been identified as a key component to space missions to support such operations as assembly and maintenance of space system (e.g. construction and maintenance of the International Space Station), and unscheduled activities to repair an element of the transportation and habitation systems that can only be accessed externally and via unpressurized areas. In order to make human transportation beyond lower earth orbit (BLEO) practical, efficiencies must be incorporated into the integrated transportation systems to reduce system mass and operational complexity. Affordability is also a key aspect to be considered in space system development; this could be achieved through commonality, modularity and component reuse. Another key aspect identified for the EVA system was the ability to produce flight worthy hardware quickly to support early missions and near Earth technology demonstrations. This paper details a conceptual architecture for a modular extravehicular activity system (MEVAS) that would meet these stated needs for EVA capability that is affordable, and that could be produced relatively quickly. Operational concepts were developed to elaborate on the defined needs and define the key capabilities, operational and design constraints, and general timelines. The operational concept lead to a high level design concept for a module that interfaces with various space transportation elements and contains the hardware and systems required to support human and telerobotic EVA; the module would not be self-propelled and would rely on an interfacing element for consumable resources. The conceptual architecture was then compared to EVA Systems used in the Shuttle Orbiter, on the International Space Station to develop high level design concepts that incorporate opportunities for cost savings through hardware reuse, and quick production through the use of existing technologies and hardware designs. An upgrade option was included to make use of the developing suitport technologies.

A Hierarchical structure of key performance indicators for operation management and continuous improvement in production systems

PubMed Central

Kang, Ningxuan; Zhao, Cong; Li, Jingshan; Horst, John A.

2018-01-01

Key performance indicators (KPIs) are critical for manufacturing operation management and continuous improvement (CI). In modern manufacturing systems, KPIs are defined as a set of metrics to reflect operation performance, such as efficiency, throughput, availability, from productivity, quality and maintenance perspectives. Through continuous monitoring and measurement of KPIs, meaningful quantification and identification of different aspects of operation activities can be obtained, which enable and direct CI efforts. A set of 34 KPIs has been introduced in ISO 22400. However, the KPIs in a manufacturing system are not independent, and they may have intrinsic mutual relationships. The goal of this paper is to introduce a multi-level structure for identification and analysis of KPIs and their intrinsic relationships in production systems. Specifically, through such a hierarchical structure, we define and layer KPIs into levels of basic KPIs, comprehensive KPIs and their supporting metrics, and use it to investigate the relationships and dependencies between KPIs. Such a study can provide a useful tool for manufacturing engineers and managers to measure and utilize KPIs for CI. PMID:29398722

Defining the Protein–Protein Interaction Network of the Human Hippo Pathway*

PubMed Central

Wang, Wenqi; Li, Xu; Huang, Jun; Feng, Lin; Dolinta, Keithlee G.; Chen, Junjie

2014-01-01

The Hippo pathway, which is conserved from Drosophila to mammals, has been recognized as a tumor suppressor signaling pathway governing cell proliferation and apoptosis, two key events involved in organ size control and tumorigenesis. Although several upstream regulators, the conserved kinase cascade and key downstream effectors including nuclear transcriptional factors have been defined, the global organization of this signaling pathway is not been fully understood. Thus, we conducted a proteomic analysis of human Hippo pathway, which revealed the involvement of an extensive protein–protein interaction network in this pathway. The mass spectrometry data were deposited to ProteomeXchange with identifier PXD000415. Our data suggest that 550 interactions within 343 unique protein components constitute the central protein–protein interaction landscape of human Hippo pathway. Our study provides a glimpse into the global organization of Hippo pathway, reveals previously unknown interactions within this pathway, and uncovers new potential components involved in the regulation of this pathway. Understanding these interactions will help us further dissect the Hippo signaling-pathway and extend our knowledge of organ size control. PMID:24126142

A Hierarchical structure of key performance indicators for operation management and continuous improvement in production systems.

PubMed

Kang, Ningxuan; Zhao, Cong; Li, Jingshan; Horst, John A

2016-01-01

Key performance indicators (KPIs) are critical for manufacturing operation management and continuous improvement (CI). In modern manufacturing systems, KPIs are defined as a set of metrics to reflect operation performance, such as efficiency, throughput, availability, from productivity, quality and maintenance perspectives. Through continuous monitoring and measurement of KPIs, meaningful quantification and identification of different aspects of operation activities can be obtained, which enable and direct CI efforts. A set of 34 KPIs has been introduced in ISO 22400. However, the KPIs in a manufacturing system are not independent, and they may have intrinsic mutual relationships. The goal of this paper is to introduce a multi-level structure for identification and analysis of KPIs and their intrinsic relationships in production systems. Specifically, through such a hierarchical structure, we define and layer KPIs into levels of basic KPIs, comprehensive KPIs and their supporting metrics, and use it to investigate the relationships and dependencies between KPIs. Such a study can provide a useful tool for manufacturing engineers and managers to measure and utilize KPIs for CI.

A scenario elicitation methodology to identify the drivers of electricity infrastructure cost in South America

NASA Astrophysics Data System (ADS)

Moksnes, Nandi; Taliotis, Constantinos; Broad, Oliver; de Moura, Gustavo; Howells, Mark

2017-04-01

Developing a set of scenarios to assess a proposed policy or future development pathways requires a certain level of information, as well as establishing the socio-economic context. As the future is difficult to predict, great care in defining the selected scenarios is needed. Even so it can be difficult to assess if the selected scenario is covering the possible solution space. Instead, this paper's methodology develops a large set of scenarios (324) in OSeMOSYS using the SAMBA 2.0 (South America Model Base) model to assess long-term electricity supply scenarios and applies a scenario-discovery statistical data mining algorithm, Patient Rule Induction Method (PRIM). By creating a multidimensional space, regions related to high and low cost can be identified as well as their key driver. The six key drivers are defined a priori in three (high, medium, low) or two levers (high, low): 1) Demand projected from GDP, population, urbanization and transport, 2) Fossil fuel price, 3) Climate change impact on hydropower, 4) Renewable technology learning rate, 5) Discount rate, 6) CO2 emission targets.

The evolution of process-based hydrologic models: historical challenges and the collective quest for physical realism

NASA Astrophysics Data System (ADS)

Clark, Martyn P.; Bierkens, Marc F. P.; Samaniego, Luis; Woods, Ross A.; Uijlenhoet, Remko; Bennett, Katrina E.; Pauwels, Valentijn R. N.; Cai, Xitian; Wood, Andrew W.; Peters-Lidard, Christa D.

2017-07-01

The diversity in hydrologic models has historically led to great controversy on the correct approach to process-based hydrologic modeling, with debates centered on the adequacy of process parameterizations, data limitations and uncertainty, and computational constraints on model analysis. In this paper, we revisit key modeling challenges on requirements to (1) define suitable model equations, (2) define adequate model parameters, and (3) cope with limitations in computing power. We outline the historical modeling challenges, provide examples of modeling advances that address these challenges, and define outstanding research needs. We illustrate how modeling advances have been made by groups using models of different type and complexity, and we argue for the need to more effectively use our diversity of modeling approaches in order to advance our collective quest for physically realistic hydrologic models.

The evolution of process-based hydrologic models: historical challenges and the collective quest for physical realism

NASA Astrophysics Data System (ADS)

Clark, M. P.; Nijssen, B.; Wood, A.; Mizukami, N.; Newman, A. J.

2017-12-01

The diversity in hydrologic models has historically led to great controversy on the "correct" approach to process-based hydrologic modeling, with debates centered on the adequacy of process parameterizations, data limitations and uncertainty, and computational constraints on model analysis. In this paper, we revisit key modeling challenges on requirements to (1) define suitable model equations, (2) define adequate model parameters, and (3) cope with limitations in computing power. We outline the historical modeling challenges, provide examples of modeling advances that address these challenges, and define outstanding research needs. We illustrate how modeling advances have been made by groups using models of different type and complexity, and we argue for the need to more effectively use our diversity of modeling approaches in order to advance our collective quest for physically realistic hydrologic models.

The core competency movement in marriage and family therapy: key considerations from other disciplines.

PubMed

Miller, John K; Todahl, Jeff L; Platt, Jason J

2010-01-01

There is a growing movement to define competency within the field of marriage and family therapy (MFT), particularly with respect to the training of practitioners and the evaluation of clinical practice. Efforts to define competency, however, transcend the practice of MFT and much can be learned from the experiences of other disciplines. Professions such as education, law, and medicine have made strides toward addressing the complex issue of competency standards in their respective fields. This article describes some ways in which the issue of competency has been approached in other professions, as well as some common dilemmas posed by adopting a competency-based orientation, to shed light on the process of defining competency in MFT. Moreover, this article identifies some of the more useful conceptualizations, modes of pedagogy, and evaluative practices found in other professions.

The challenges in defining and measuring diagnostic error.

PubMed

Zwaan, Laura; Singh, Hardeep

2015-06-01

Diagnostic errors have emerged as a serious patient safety problem but they are hard to detect and complex to define. At the research summit of the 2013 Diagnostic Error in Medicine 6th International Conference, we convened a multidisciplinary expert panel to discuss challenges in defining and measuring diagnostic errors in real-world settings. In this paper, we synthesize these discussions and outline key research challenges in operationalizing the definition and measurement of diagnostic error. Some of these challenges include 1) difficulties in determining error when the disease or diagnosis is evolving over time and in different care settings, 2) accounting for a balance between underdiagnosis and overaggressive diagnostic pursuits, and 3) determining disease diagnosis likelihood and severity in hindsight. We also build on these discussions to describe how some of these challenges can be addressed while conducting research on measuring diagnostic error.

Defining an end state for CO2 sequestration and EOR in North America

DOE Office of Scientific and Technical Information (OSTI.GOV)

Friedmann, S J

2006-04-20

CO{sub 2} capture and storage (CCS) presents a challenge to long-range planners, economic interests, regulators, law-makers, and other stakeholders and decision makers. To improve and optimize the use of limited resources and finances, it is important to define an end state for CCS. This ends state should be defined around desired goals and reasonable timelines for execution. While this definition may have substantial technology, policy or economic implications, it need not be prescriptive in terms of technology pathway, policy mechanism, or economic targets. To illustrate these concerns, this paper will present a credible vision of what an end state formore » North American might look like. From that, examples of key investment and planning decisions are provided to illustrate the value of end-state characterization.« less

Does the specialist nurse enhance or deskill the general nurse?

PubMed

Marshall, Z; Luffingham, N

Much conflict and confusion surrounds the title and role of the specialist nurse, leading in some instances to disharmony between general and specialist nurses. It has been suggested that too many highly specialized nurses in a general area may lead to a deskilled workforce and fragmented care. Attempts to define the key concepts of specialist practice as described by the UKCC has resulted in elitism, conflict and abuse of the title. One suggestion to eliminate this conflict is for specialist nurses to achieve key competencies that encompass the role of the clinical expert. These key competencies should be devised by specialist nurses, in the absence of national guidelines, and be agreed by employers. They should incorporate the key roles of: change agent, expert clinician, educator, researcher and coordinator. It is contended that if all concerned have a clearer definition of the title, role and what is expected from the specialist nurse then this will result in reduced conflict and improved quality of care.

Key metrics for HFIR HEU and LEU models

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ilas, Germina; Betzler, Benjamin R.; Chandler, David

This report compares key metrics for two fuel design models of the High Flux Isotope Reactor (HFIR). The first model represents the highly enriched uranium (HEU) fuel currently in use at HFIR, and the second model considers a low-enriched uranium (LEU) interim design fuel. Except for the fuel region, the two models are consistent, and both include an experiment loading that is representative of HFIR's current operation. The considered key metrics are the neutron flux at the cold source moderator vessel, the mass of 252Cf produced in the flux trap target region as function of cycle time, the fast neutronmore » flux at locations of interest for material irradiation experiments, and the reactor cycle length. These key metrics are a small subset of the overall HFIR performance and safety metrics. They were defined as a means of capturing data essential for HFIR's primary missions, for use in optimization studies assessing the impact of HFIR's conversion from HEU fuel to different types of LEU fuel designs.« less

Secure password-based authenticated key exchange for web services

DOE Office of Scientific and Technical Information (OSTI.GOV)

Liang, Fang; Meder, Samuel; Chevassut, Olivier

This paper discusses an implementation of an authenticated key-exchange method rendered on message primitives defined in the WS-Trust and WS-SecureConversation specifications. This IEEE-specified cryptographic method (AuthA) is proven-secure for password-based authentication and key exchange, while the WS-Trust and WS-Secure Conversation are emerging Web Services Security specifications that extend the WS-Security specification. A prototype of the presented protocol is integrated in the WSRF-compliant Globus Toolkit V4. Further hardening of the implementation is expected to result in a version that will be shipped with future Globus Toolkit releases. This could help to address the current unavailability of decent shared-secret-based authentication options inmore » the Web Services and Grid world. Future work will be to integrate One-Time-Password (OTP) features in the authentication protocol.« less

Progress in defining clinically meaningful changes for clinical trials in nonrenal manifestations of SLE disease activity.

PubMed

Choi, Chan-Bum; Liang, Matthew H; Bae, Sang-Cheol

2016-01-06

Since the 2002 Dusseldorf meeting, one new agent, Benlysta, has been approved by the US Food and Drug Administration for systemic lupus erythematosus. Experiences from the field in conducting trials of all the agents tested during this period have provided valuable practical insights. There has been incremental progress in defining the minimal clinically important difference (MCID) of key disease manifestations and the view is largely that of the health care providers and not that of the person suffering the disease. This basic methodological work on the MCID should improve the efficiency and the clinical relevance of future trials and their design.

Chaos and noise.

PubMed

He, Temple; Habib, Salman

2013-09-01

Simple dynamical systems--with a small number of degrees of freedom--can behave in a complex manner due to the presence of chaos. Such systems are most often (idealized) limiting cases of more realistic situations. Isolating a small number of dynamical degrees of freedom in a realistically coupled system generically yields reduced equations with terms that can have a stochastic interpretation. In situations where both noise and chaos can potentially exist, it is not immediately obvious how Lyapunov exponents, key to characterizing chaos, should be properly defined. In this paper, we show how to do this in a class of well-defined noise-driven dynamical systems, derived from an underlying Hamiltonian model.

Conducting Clinical Research with Prescription Opioid Dependence: Defining the Population

PubMed Central

Weiss, Roger D.; Potter, Jennifer S.; Copersino, Marc L.; Prather, Kristi; Jacobs, Petra; Provost, Scott; Chim, David; Selzer, Jeffrey; Ling, Walter

2010-01-01

Most treatment studies of opioid-dependent populations have focused predominantly on heroin users, despite a recent increase in those dependent upon prescription opioids. A key methodological challenge involved in studying the latter group involves defining the population. Specifically, researchers must decide whether to include 1) concurrent heroin users and 2) individuals with pain. The multi-site Prescription Opioid Addiction Treatment Study is examining treatments for this population. This paper describes various inclusion criteria considered by the study team related to heroin use and pain. The goal was to recruit a distinct but generalizable population of individuals dependent upon prescription opioids. PMID:20163386

Objective comparison of particle tracking methods.

PubMed

Chenouard, Nicolas; Smal, Ihor; de Chaumont, Fabrice; Maška, Martin; Sbalzarini, Ivo F; Gong, Yuanhao; Cardinale, Janick; Carthel, Craig; Coraluppi, Stefano; Winter, Mark; Cohen, Andrew R; Godinez, William J; Rohr, Karl; Kalaidzidis, Yannis; Liang, Liang; Duncan, James; Shen, Hongying; Xu, Yingke; Magnusson, Klas E G; Jaldén, Joakim; Blau, Helen M; Paul-Gilloteaux, Perrine; Roudot, Philippe; Kervrann, Charles; Waharte, François; Tinevez, Jean-Yves; Shorte, Spencer L; Willemse, Joost; Celler, Katherine; van Wezel, Gilles P; Dan, Han-Wei; Tsai, Yuh-Show; Ortiz de Solórzano, Carlos; Olivo-Marin, Jean-Christophe; Meijering, Erik

2014-03-01

Particle tracking is of key importance for quantitative analysis of intracellular dynamic processes from time-lapse microscopy image data. Because manually detecting and following large numbers of individual particles is not feasible, automated computational methods have been developed for these tasks by many groups. Aiming to perform an objective comparison of methods, we gathered the community and organized an open competition in which participating teams applied their own methods independently to a commonly defined data set including diverse scenarios. Performance was assessed using commonly defined measures. Although no single method performed best across all scenarios, the results revealed clear differences between the various approaches, leading to notable practical conclusions for users and developers.

Improving Small Interfering RNA Delivery In Vivo Through Lipid Conjugation.

PubMed

Osborn, Maire F; Khvorova, Anastasia

2018-05-10

RNA interference (RNAi)-based therapeutics are approaching clinical approval for genetically defined diseases. Current clinical success is a result of significant innovations in the development of chemical architectures that support sustained, multi-month efficacy in vivo following a single administration. Conjugate-mediated delivery has established itself as the most promising platform for safe and targeted small interfering RNA (siRNA) delivery. Lipophilic conjugates represent a major class of modifications that improve siRNA pharmacokinetics and enable efficacy in a broad range of tissues. Here, we review current literature and define key features and limitations of this approach for in vivo modulation of gene expression.

Intelligent Wireless Sensor Networks for System Health Monitoring

NASA Technical Reports Server (NTRS)

Alena, Rick

2011-01-01

Wireless sensor networks (WSN) based on the IEEE 802.15.4 Personal Area Network (PAN) standard are finding increasing use in the home automation and emerging smart energy markets. The network and application layers, based on the ZigBee 2007 Standard, provide a convenient framework for component-based software that supports customer solutions from multiple vendors. WSNs provide the inherent fault tolerance required for aerospace applications. The Discovery and Systems Health Group at NASA Ames Research Center has been developing WSN technology for use aboard aircraft and spacecraft for System Health Monitoring of structures and life support systems using funding from the NASA Engineering and Safety Center and Exploration Technology Development and Demonstration Program. This technology provides key advantages for low-power, low-cost ancillary sensing systems particularly across pressure interfaces and in areas where it is difficult to run wires. Intelligence for sensor networks could be defined as the capability of forming dynamic sensor networks, allowing high-level application software to identify and address any sensor that joined the network without the use of any centralized database defining the sensors characteristics. The IEEE 1451 Standard defines methods for the management of intelligent sensor systems and the IEEE 1451.4 section defines Transducer Electronic Datasheets (TEDS), which contain key information regarding the sensor characteristics such as name, description, serial number, calibration information and user information such as location within a vehicle. By locating the TEDS information on the wireless sensor itself and enabling access to this information base from the application software, the application can identify the sensor unambiguously and interpret and present the sensor data stream without reference to any other information. The application software is able to read the status of each sensor module, responding in real-time to changes of PAN configuration, providing the appropriate response for maintaining overall sensor system function, even when sensor modules fail or the WSN is reconfigured. The session will present the architecture and technical feasibility of creating fault-tolerant WSNs for aerospace applications based on our application of the technology to a Structural Health Monitoring testbed. The interim results of WSN development and testing including our software architecture for intelligent sensor management will be discussed in the context of the specific tradeoffs required for effective use. Initial certification measurement techniques and test results gauging WSN susceptibility to Radio Frequency interference are introduced as key challenges for technology adoption. A candidate Developmental and Flight Instrumentation implementation using intelligent sensor networks for wind tunnel and flight tests is developed as a guide to understanding key aspects of the aerospace vehicle design, test and operations life cycle.

Maori responsiveness in health and medical research: key issues for researchers (part 1).

PubMed

Sporle, Andrew; Koea, Jonathan

2004-08-06

Application for contestable government-research funding and ethical approval requires researchers to outline how their intended research project contributes to Maori development or advancement. When formulating their research proposals, the key issues for researchers are research utility, defining Maori, informed consent, confidentiality, issues with human tissues and genetic material, participant remuneration and recognition (koha), intellectual property, and involvement of local Maori health or social services. The most common Maori responsiveness issues in research applications can be readily approached by researchers who address straightforward methodological concerns, by working through precedents established by peers and colleagues, as well as by working with end-users of their research.

Liver physiological polyploidization: MicroRNA-122 a key regulator.

PubMed

Celton-Morizur, Séverine; Desdouets, Chantal

2017-03-01

Polyploidy is defined as an increase in genome DNA content and is observed in all mammalian species. Polyploidy is a common characteristic of hepatocytes. Polyploidization occurs mainly during liver development, but also in adults with increasing age or due to cellular stress. During liver development, hepatocytes polyploidization occurs through cytokinesis failure leading to the genesis of binucleate hepatocytes. Recently, Hsu et al. demonstrated that miR-122 is a key regulator of hepatic binucleation. In fact, during liver development, miR-122 directly antagonizes procytokinesis targets and thus induces cytokinesis failure leading to the genesis of binucleate hepatocytes. Copyright © 2016 Elsevier Masson SAS. All rights reserved.

Ten key principles for successful health systems integration.

PubMed

Suter, Esther; Oelke, Nelly D; Adair, Carol E; Armitage, Gail D

2009-01-01

Integrated health systems are considered part of the solution to the challenge of sustaining Canada's healthcare system. This systematic literature review was undertaken to guide decision-makers and others to plan for and implement integrated health systems. This review identified 10 universal principles of successfully integrated healthcare systems that may be used by decision-makers to assist with integration efforts. These principles define key areas for restructuring and allow organizational flexibility and adaptation to local context. The literature does not contain a one-size-fits-all model or process for successful integration, nor is there a firm empirical foundation for specific integration strategies and processes.

Learning lessons from drugs that have recently entered the market.

PubMed

Teague, Simon J

2011-05-01

Which projects in the drug discovery field are most likely to be successful? In this article, I provide guidelines for answering this question by examining recent drug market entrants in detail, in particular their route of administration, trial design, novelty, therapeutic target and toxicities. I identify targets, trials and organizations as the key issues that are currently leading to the poor productivity in the pharmaceutical industry. Here, I outline some solutions and reasons for optimism, and suggest that the key determinants for success in drug discovery can be defined by studying recently launched drugs. Copyright © 2011 Elsevier Ltd. All rights reserved.

Amortized entanglement of a quantum channel and approximately teleportation-simulable channels

NASA Astrophysics Data System (ADS)

Kaur, Eneet; Wilde, Mark M.

2018-01-01

This paper defines the amortized entanglement of a quantum channel as the largest difference in entanglement between the output and the input of the channel, where entanglement is quantified by an arbitrary entanglement measure. We prove that the amortized entanglement of a channel obeys several desirable properties, and we also consider special cases such as the amortized relative entropy of entanglement and the amortized Rains relative entropy. These latter quantities are shown to be single-letter upper bounds on the secret-key-agreement and PPT-assisted quantum capacities of a quantum channel, respectively. Of especial interest is a uniform continuity bound for these latter two special cases of amortized entanglement, in which the deviation between the amortized entanglement of two channels is bounded from above by a simple function of the diamond norm of their difference and the output dimension of the channels. We then define approximately teleportation- and positive-partial-transpose-simulable (PPT-simulable) channels as those that are close in diamond norm to a channel which is either exactly teleportation- or PPT-simulable, respectively. These results then lead to single-letter upper bounds on the secret-key-agreement and PPT-assisted quantum capacities of channels that are approximately teleportation- or PPT-simulable, respectively. Finally, we generalize many of the concepts in the paper to the setting of general resource theories, defining the amortized resourcefulness of a channel and the notion of ν-freely-simulable channels, connecting these concepts in an operational way as well.

The design briefing process matters: a case study on telehealthcare device providers in the UK.

PubMed

Yang, Fan; Renda, Gianni

2018-01-23

The telehealthcare sector has been expanding steadily in the UK. However, confusing, complex and unwieldy designs of telehealthcare devices are at best, less effective than they could be, at worst, they are potentially dangerous to the users. This study investigated the factors within the new product development process that hindered satisfactory product design outcomes, through working collaboratively with a leading provider based in the UK. This study identified that there are too many costly late-stage design changes; a critical and persistent problem area ripe for improvement. The findings from analyzing 30 recent devices, interviewing key stakeholders and observing on-going projects further revealed that one major cause of the issue was poor practice in defining and communicating the product design criteria and requirements. Addressing the characteristics of the telehealthcare industry, such as multiple design commissioners and frequent deployment of design subcontracts, this paper argues that undertaking a robust process of creating the product design brief is the key to improving the outcomes of telehealthcare device design, particularly for the small and medium-sized enterprises dominating the sector. Implications for rehabilitation Product design criteria and requirements are frequently ill-defined and ineffectively communicated to the designers within the processes of developing new telehealthcare devices. The absence of a (robust) process of creating the design brief is the root cause of the identified issues in defining and communicating the design task. Deploying a formal process of creating the product design brief is particularly important for the telehealthcare sector.

Is the learning curve endless? One surgeon's experience with robotic prostatectomy

NASA Astrophysics Data System (ADS)

Patel, Vipul; Thaly, Rahul; Shah, Ketul

2007-02-01

Introduction: After performing 1,000 robotic prostatectomies we reflected back on our experience to determine what defined the learning curve and the essential elements that were the keys to surmounting it. Method: We retrospectively assessed our experience to attempt to define the learning curve(s), key elements of the procedure, technical refinements and changes in technology that facilitated our progress. Result: The initial learning curve to achieve basic competence and the ability to smoothly perform the procedure in less than 4 hours with acceptable outcomes was approximately 25 cases. A second learning curve was present between 75-100 cases as we approached more complicated patients. At 200 cases we were comfortably able to complete the procedure routinely in less than 2.5 hours with no specific step of the procedure hindering our progression. At 500 cases we had the introduction of new instrumentation (4th arm, biopolar Maryland, monopolar scissors) that changed our approach to the bladder neck and neurovascular bundle dissection. The most challenging part of the procedure was the bladder neck dissection. Conclusion: There is no single parameter that can be used to assess or define the learning curve. We used a combination of factors to make our subjective definition this included: operative time, smoothness of technical progression during the case along with clinical outcomes. The further our case experience progressed the more we expected of our outcomes, thus we continually modified our technique and hence embarked upon yet a new learning curve.

A novel performance monitoring framework for health research systems: experiences of the National Institute for Health Research in England

PubMed Central

2011-01-01

Background The National Institute for Health Research (NIHR) was established in 2006 with the aim of creating an applied health research system embedded within the English National Health Service (NHS). NIHR sought to implement an approach for monitoring its performance that effectively linked early indicators of performance with longer-term research impacts. We attempted to develop and apply a conceptual framework for defining appropriate key performance indicators for NIHR. Method Following a review of relevant literature, a conceptual framework for defining performance indicators for NIHR was developed, based on a hybridisation of the logic model and balanced scorecard approaches. This framework was validated through interviews with key NIHR stakeholders and a pilot in one division of NIHR, before being refined and applied more widely. Indicators were then selected and aggregated to create a basket of indicators aligned to NIHR's strategic goals, which could be reported to NIHR's leadership team on a quarterly basis via an oversight dashboard. Results Senior health research system managers and practitioners endorsed the conceptual framework developed and reported satisfaction with the breadth and balance of indicators selected for reporting. Conclusions The use of the hybrid conceptual framework provides a pragmatic approach to defining performance indicators that are aligned to the strategic aims of a health research system. The particular strength of this framework is its capacity to provide an empirical link, over time, between upstream activities of a health research system and its long-term strategic objectives. PMID:21435265

Toward defining deep brain stimulation targets in MNI space: A subcortical atlas based on multimodal MRI, histology and structural connectivity.

PubMed

Ewert, Siobhan; Plettig, Philip; Li, Ningfei; Chakravarty, M Mallar; Collins, D Louis; Herrington, Todd M; Kühn, Andrea A; Horn, Andreas

2018-04-15

Three-dimensional atlases of subcortical brain structures are valuable tools to reference anatomy in neuroscience and neurology. For instance, they can be used to study the position and shape of the three most common deep brain stimulation (DBS) targets, the subthalamic nucleus (STN), internal part of the pallidum (GPi) and ventral intermediate nucleus of the thalamus (VIM) in spatial relationship to DBS electrodes. Here, we present a composite atlas based on manual segmentations of a multimodal high resolution brain template, histology and structural connectivity. In a first step, four key structures were defined on the template itself using a combination of multispectral image analysis and manual segmentation. Second, these structures were used as anchor points to coregister a detailed histological atlas into standard space. Results show that this approach significantly improved coregistration accuracy over previously published methods. Finally, a sub-segmentation of STN and GPi into functional zones was achieved based on structural connectivity. The result is a composite atlas that defines key nuclei on the template itself, fills the gaps between them using histology and further subdivides them using structural connectivity. We show that the atlas can be used to segment DBS targets in single subjects, yielding more accurate results compared to priorly published atlases. The atlas will be made publicly available and constitutes a resource to study DBS electrode localizations in combination with modern neuroimaging methods. Copyright © 2017 Elsevier Inc. All rights reserved.

Transfusion service disaster planning.

PubMed

Bundy, K L; Foss, M L; Stubbs, J R

2008-01-01

The Mayo Clinic, in Rochester, Minnesota, recently set forth a directive to develop a Mayo Emergency Incident Command System (MEICS) plan to respond to major disasters. The MEICS plan that was developed interfaces with national response plans to ensure effective communication and coordination between our institution and local, state, and federal agencies to establish a common language and communication structure. The MEICS plan addresses multiple aspects of dealing with resource needs during a crisis, including the need for blood and transfusion medicine services. The MEICS plan was developed to supplement our current local emergency preparedness procedures and provide a mechanism for responding to the escalating severity of an emergency to deal with situations of a magnitude that is outside the normal experience. A plan was developed to interface the existing Transfusion Medicine disaster plan standard operating procedures (SOP) with the institutional and Department of Laboratory Medicine (DLMP) MEICS plans. The first step in developing this interface was defining MEICS. Other major steps were defining the chain of command, developing a method for visually indicating who is "in charge," planning communication, defining the actions to be taken, assessing resource needs, developing flowcharts and updating SOPs, and developing a blood rationing team to deal with anticipated blood shortages. Several key features of the interface and updated disaster plan that were developed are calling trees for response personnel, plans for relocating leadership to alternative command centers, and action sheets to assist with resource assessment. The action sheets also provide documentation of key actions by response personnel.

Advocacy Groups and the Discourse of Teacher Policy Reform: An Analysis of Policy Narratives

ERIC Educational Resources Information Center

Harrison, Christopher

2017-01-01

In recent years, several states have engaged in significant action surrounding a key policy area-- teacher policy reform. In Florida, for example, the passage of Senate Bill (SB) 736, the Student Success Act, heralded substantial shifts in the boundaries defining the profession of teaching in the state. Through SB 736 and its unsuccessful…

Using Historical Empathy to Excite Students about the Study of History: Can You Empathize with Neville Chamberlain?

ERIC Educational Resources Information Center

Foster, Stuart

1999-01-01

Describes a historical empathy lesson that requires high school students to understand, explain, and evaluate why Neville Chamberlain followed the policy of appeasement in his negotiations with Adolf Hitler. Defines historical empathy and includes an appendix with list of key events, student investigation sheet, and resource materials. (CMK)

Self Evaluation and Peer Observation of Early Career Teachers in a Standards-Based Context: Preliminary Results.

ERIC Educational Resources Information Center

Hansen, Joe B.; Schalock, Mark D.; McConney, Andrew; Rudd, Andy

This study examined the relationships between teachers' self-assessment and their ratings by master teachers on key dimensions of proficiency as defined by Oregon's Continuing Teaching Licensure (CTL) requirements, and it explored differences between teacher behaviors and practices as a function of their teacher preparation programs. It also…

Editorial: Challenges and solutions in GW calculations for complex systems

NASA Astrophysics Data System (ADS)

Giustino, F.; Umari, P.; Rubio, A.

2012-09-01

We report key advances in the area of GW calculations, review the available software implementations and define standardization criteria to render the comparison between GW calculations from different codes meaningful, and identify future major challenges in the area of quasiparticle calculations. This Topical Issue should be a reference point for further developments in the field.

The New Youth Entrepreneur: Getting Ready for Entrepreneurship. Opportunities-They Are All Around You. Module 2.

ERIC Educational Resources Information Center

Kourilsky, Marilyn; And Others

The New Youth Entrepreneur curriculum is a series of 12 youth-oriented educational modules containing instructional materials, learning activities, and checkup exercises designed to teach students key elements of entrepreneurship. This document is the second module, designed to help students define the notion of opportunity, determine sources of…

Getting to the Point: Storying the United States Military Academy’s and Its Preparatory School’s English Program.

DTIC Science & Technology

1998-01-01

34modules" identified as key to the needed changes at the Prep School (Final 11). Three modules— composition/grammar, precalculus mathematics, and...composition/grammar and performance enhancement, and precalculus mathematics) set out to determine how to define mathematics "gateways," to examine

Re-Thinking School-University Collaboration: Agenda for the 21st Century

ERIC Educational Resources Information Center

Wasonga, C. O.; Rari, B. O.; Wanzare, Z. O.

2011-01-01

Collaboration is a hard and challenging endeavor. It takes all the key players to make it happen. This paper discusses our current thinking about school-university collaboration. In it, we define what collaboration involves in the context of universities and schools. Next, we discuss what we believe are the essential benefits of effective…

Coaching for Performance. Second Edition. People Skills for Professionals Series.

ERIC Educational Resources Information Center

Whitmore, John

This book teaches the skills and art of good coaching and how to realize its value in unlocking people's potential to maximize their own performance. Chapters 1-3 define coaching and its business application, discuss the manager as coach and the manager's role, and examine the context of change. Chapter 4 considers the two key elements of…

ACHP | News | The ACHP Announces New Director ...

Science.gov Websites

Section 106 cases that have defined the shape of the Section 106 process and the ACHP's role in it have ;we are looking forward to Reid assuming this important role, and we are delighted to be able to . Additionally, the ACHP has a key role in administering the Administration's Preserve America Initiative

Life cycle impacts of manufacturing redwood decking in Northern California

Treesearch

Richard D. Bergman; Elaine Oneil; Ivan L. Eastin; Han-Sup Han

2014-01-01

Awareness of the environmental footprint of building construction and use has led to increasing interest in green building. Defining a green building is an evolving process with life cycle inventory and life cycle impact assessment (LCIA) emerging as key tools in that evolution and definition process. This study used LCIA to determine the environmental footprint...

40 CFR 370.66 - How are key words in this part defined?

Code of Federal Regulations, 2014 CFR

2014-07-01

... include: (1) Any food, food additive, color additive, drug, or cosmetic regulated by the Food and Drug... under 29 CFR 1910.1200) and other hazardous chemicals that cause an adverse effect to a target organ and which effect usually occurs rapidly as a result of short-term exposure and is of short duration; (2...

40 CFR 370.66 - How are key words in this part defined?

Code of Federal Regulations, 2012 CFR

2012-07-01

... include: (1) Any food, food additive, color additive, drug, or cosmetic regulated by the Food and Drug... under 29 CFR 1910.1200) and other hazardous chemicals that cause an adverse effect to a target organ and which effect usually occurs rapidly as a result of short-term exposure and is of short duration; (2...

40 CFR 370.66 - How are key words in this part defined?

Code of Federal Regulations, 2011 CFR

2011-07-01

... include: (1) Any food, food additive, color additive, drug, or cosmetic regulated by the Food and Drug... under 29 CFR 1910.1200) and other hazardous chemicals that cause an adverse effect to a target organ and which effect usually occurs rapidly as a result of short-term exposure and is of short duration; (2...

40 CFR 370.66 - How are key words in this part defined?

Code of Federal Regulations, 2013 CFR

2013-07-01

... include: (1) Any food, food additive, color additive, drug, or cosmetic regulated by the Food and Drug... under 29 CFR 1910.1200) and other hazardous chemicals that cause an adverse effect to a target organ and which effect usually occurs rapidly as a result of short-term exposure and is of short duration; (2...

Stakeholders' Voices: Defining Needs of Students with Emotional and Behavioral Disorders Transitioning between School Settings

ERIC Educational Resources Information Center

Buchanan, Rohanna; Nese, Rhonda N. T.; Clark, Miriam

2016-01-01

Students with emotional and behavioral disorders (EBD) too often do not receive adequate services or care in their school settings, particularly during transitions in educational placements. In addition, school support teams often struggle with creating transition plans that honor the needs of students with input from key stakeholders responsible…

Understanding key issues of sustainable wood production in the Pacific Northwest.

Treesearch

Robert L. Deal; Seth M. White

2005-01-01

Researchers involved with the Pacific Northwest (PNW) Research Station Sustainable Wood Production Initiative have outlined some of the barriers and opportunities for sustainable wood production in the region. Sustainable wood production is defined as the capacity of forests to produce wood, products, and services on a long-term basis and in the context of human...

Questions from Afar: The Influence of Outsideness on Web-Based Conversation

ERIC Educational Resources Information Center

Deed, Craig; Edwards, Anthony; Gomez, Viviana

2015-01-01

This paper defines the metaphor of outsideness in relation to web-based interaction. Outsideness is conceived of as a key influence in online academic conversation. In particular, through the sharing of cultural perspectives, asking questions to resolve doubt, and collaborative writing and re-writing as a basis for shaping ideas through reasoning.…

Older Computer-Literate Women: Their Motivations, Obstacles, and Paths to Success

ERIC Educational Resources Information Center

Rosenthal, Rita L.

2008-01-01

With the ever-increasing impact of computerized communication and information delivery, the need to encourage learning about technology is critical for the older population today as well as for soon-to-be retirees. Adler (1996, 2002, 2003) has described and defined the key benefits to seniors: enhanced communication with family and friends,…

Technology and Technological Knowledge: A Challenge for School Curricula

ERIC Educational Resources Information Center

Gibson, Ken

2008-01-01

In contrast to subjects such as mathematics and the sciences, it has been argued that technology education lacks a clear definition and a clearly defined knowledge base. This discursive article seeks to inform the debate by highlighting the matter of subject definition and in addition to examine the key issue of the knowledge which underpins…

Girls' Challenge Seeking: How Outdoor Exposure Can Support Girls in Taking Positive Risks

ERIC Educational Resources Information Center

Tsikalas, Kallen; Martin, Karyn L.

2015-01-01

Challenge seeking is an important component of children's personal and academic development. Defined in this paper as a set of beliefs and behaviors that propels individuals to initiate and persist at difficult ventures, challenge seeking is a key indicator of mastery goal orientation. This orientation has been linked with a number of positive and…

Pathways to Improvement: Using Psychological Strategies to Help College Students Master Developmental Math

ERIC Educational Resources Information Center

Silva, Elena; White, Taylor

2013-01-01

Drawing on a research base developed over many years in education, Carnegie is testing a set of strategies to help students persist and succeed academically. This kind of persistence, what the researchers and faculty who developed the Pathways call "productive persistence," is a key driver of Quantway® and Statway®. Broadly defined,…

Keys to the Future of American Business. Proceedings of the Creativity, Innovation and Entrepreneurship Conference (5th, Cincinnati, Ohio, March 18-19, 1988).

ERIC Educational Resources Information Center

Solomon, George T., Ed.; And Others

The following papers are included: "Defining the Win and Thereby Lessening the Losses for Successful Entrepreneurs" (Arthur Lipper III); "It Can Be Done" (Anthony Lemme); "A Self-Portrait of Entrepreneurs" (George T. Solomon, Erik K. Winslow); "Software Entrepreneurship: Lessons Learned" (John Coyne);…

From Loose Groups to Effective Teams: The Nine Key Factors of the Team Landscape.

ERIC Educational Resources Information Center

Sheard, A. G.; Kakabadse, A. P.

2002-01-01

A loose group of individuals working on a task differs from an effective team on nine factors: clearly defined goals, priorities, roles and responsibilities, self-awareness, leadership, group dynamics, communications, content, and infrastructure. Ways to eliminate barriers and speed formation of effective teams could be based on those factors.…

Research into the Specific Aspects of Internal Conflict Displays in the Course of Professional Identification

ERIC Educational Resources Information Center

Rensh, Marina A.; Kosyakova, Inessa V.; Agafonova, Anna N.

2016-01-01

The applicability of the researched issue is preconditioned by the need for detecting key determinants which define the process of the person's professional development, identification with the professional environment, and sources of professional self-efficacy. The purpose of the article is to provide the deliverables of the empiric research for…

[Recommendations for the evaluation and follow-up of the continuous quality improvement].

PubMed

Maurellet-Evrard, S; Daunizeau, A

2013-06-01

Continual improvement of the quality in a medical laboratory is based on the implementation of tools for systematically evaluate the quality management system and its ability to meet the objectives defined. Monitoring through audit and management review, addressing complaints and nonconformities and performing client satisfaction survey are the key for the continual improvement.

Career Survival: Strategic Job and Role Planning. Pfeiffer Career Series.

ERIC Educational Resources Information Center

Schein, Edgar H.

This book was designed to help managers and employees to decipher the two crucial elements in work design and human resource planning: the role network that surrounds every position and the key stakeholders whose expectations define the essence of the job. It provides a structured process for analyzing one's own job as well as the jobs of…

Commitment, Educative Action and Adults. Learning Programmes with a Social Purpose.

ERIC Educational Resources Information Center

O'Sullivan, Denis

This book analyzes socially committed programs defined as systematic efforts to bring about social change through educative action. Chapter 1 provides examples of socially committed programs and an overview of the book. Chapters 2-7 explore six key questions about seeking to change people in a socially committed way. Chapter 2 looks at those who…

The Role of Learning Goals in Building a Knowledge Base for Elementary Mathematics Teacher Education

ERIC Educational Resources Information Center

Jansen, Amanda; Bartell, Tonya; Berk, Dawn

2009-01-01

In this article, we describe features of learning goals that enable indexing knowledge for teacher education. Learning goals are the key enabler for building a knowledge base for teacher education; they define what counts as essential knowledge for prospective teachers. We argue that 2 characteristics of learning goals support knowledge-building…

Towards an Integrated Second-Language Pedagogy for Foreign and Community/Heritage Languages in Multilingual Britain

ERIC Educational Resources Information Center

Anderson, Jim

2008-01-01

A key issue, which has undermined the development of community/heritage language teaching in the UK over recent decades, has been the need to define an appropriate pedagogical approach which takes account of the bilingual and bicultural background of the majority of learners studying these languages. Within the National Curriculum, community…

If We Could Plan the Next 10 Years in Science Education...

ERIC Educational Resources Information Center

Mansell, Warwick

2013-01-01

Two major sessions at the 2013 ASE Summer Celebration Conference in Hatfield offered teachers (and other educators) the chance to debate and define the key issues facing science education over the next 10 years. Participants were asked to suggest the important issues. Then those with similar proposals were put into groups to develop the idea ready…

Wiki Activities in Blended Learning for Health Professional Students: Enhancing Critical Thinking and Clinical Reasoning Skills

ERIC Educational Resources Information Center

Snodgrass, Suzanne

2011-01-01

Health professionals use critical thinking, a key problem solving skill, for clinical reasoning which is defined as the use of knowledge and reflective inquiry to diagnose a clinical problem. Teaching these skills in traditional settings with growing class sizes is challenging, and students increasingly expect learning that is flexible and…

When I Grow Up: Assessing American Children's Perspectives on College and Career Readiness through Drawings

ERIC Educational Resources Information Center

Turner, Jennifer Danridge; Albro, Jennifer

2017-01-01

College and career readiness has become a key educational priority in the United States. Framed by neoliberal discourses, current conceptions of college and career readiness narrowly define literacy as discrete sets of cognitive skills and curricular knowledge and reduce literacy learning to scores on high-stakes assessments. To disrupt these…

If the Real World Were Irrelevant, so to Speak: The role of propositional truth-value in counterfactual sentence comprehension

ERIC Educational Resources Information Center

Nieuwland, Mante S.; Martin, Andrea E.

2012-01-01

Propositional truth-value can be a defining feature of a sentence's relevance to the unfolding discourse, and establishing propositional truth-value in context can be key to successful interpretation. In the current study, we investigate its role in the comprehension of counterfactual conditionals, which describe imaginary consequences of…

Needs Analysis in ESP Context: Saudi Engineering Students as a Case Study

ERIC Educational Resources Information Center

Alsamadani, Hashem Ahmed

2017-01-01

Needs analysis can be a vital asset for teachers of English for specific purposes (ESP) to identify their learners' key requirements or needs and determine the areas in which they are lacking skills. Against this background, this study was undertaken during the academic year 2015-16 to define the English language needs of engineering students…

Una Mejor Opportunidad para Aprender: La Educacion Bilingue Bicultural (A Better Chance to Learn: Bilingual-Bicultural Education).

ERIC Educational Resources Information Center

Commission on Civil Rights, Washington, DC.

The effectiveness of bilingual bicultural education as a means of increasing the opportunities of language minority students is examined in this report, which is addressed to educators and the general public. First, an introduction defines key terms, briefly outlines controversies which surround bilingual education, and describes the contents of…

Developing Open Source Software To Advance High End Computing. Report to the President.

ERIC Educational Resources Information Center

National Coordination Office for Information Technology Research and Development, Arlington, VA.

This is part of a series of reports to the President and Congress developed by the President's Information Technology Advisory Committee (PITAC) on key contemporary issues in information technology. This report defines open source software, explains PITAC's interest in this model, describes the process used to investigate issues in open source…

40 CFR 355.61 - How are key words in this part defined?

Code of Federal Regulations, 2010 CFR

2010-07-01

... 1910.1200(c), except that this term does not include: (1) Any food, food additive, color additive, drug, or cosmetic regulated by the Food and Drug Administration. (2) Any substance present as a solid in..., including fish, which produced and sold, or normally would have produced and sold, $1,000 or more of...

The Key to Leadership Effectiveness--Leader Authenticity.

ERIC Educational Resources Information Center

Henderson, James E.

When an education leader develops and maintains policies that line up with the imperatives of ethical and authentic behavior, this defines the character of both the leader and the organization. Some of the questions surrounding this assertion are examined in this paper. It looks at what it means when a leader behaves in an authentic fashion, how…

The Public Community College in America: Its History, Present Condition, and Future Outlook with Special Reference to Finance.

ERIC Educational Resources Information Center

Edwards, Nancy Joan

The development, current status, and future prospects of community colleges are examined in this study with special emphasis on finance and funding concerns. Introductory material outlines study objectives, methodology, and purposes; defines key terms; and emphasizes the importance of college planning. Chapter 1 presents a history of the community…

Testing the Efficiency of Markov Chain Monte Carlo with People Using Facial Affect Categories

ERIC Educational Resources Information Center

Martin, Jay B.; Griffiths, Thomas L.; Sanborn, Adam N.

2012-01-01

Exploring how people represent natural categories is a key step toward developing a better understanding of how people learn, form memories, and make decisions. Much research on categorization has focused on artificial categories that are created in the laboratory, since studying natural categories defined on high-dimensional stimuli such as…

Issues in Designing a Hypermedia Document System: The Intermedia Case Study.

ERIC Educational Resources Information Center

Yankelovich, Nicole; And Others

1986-01-01

Intermedia, a hypermedia system developed at Brown University's Institute for Research (Rhode Island) in Information and Scholarship, is first described, and then used as a case study to explore a number of key issues that software designers must consider in the development of hypermedia document systems. A hypermedia document system is defined as…

A hardware-oriented algorithm for floating-point function generation

NASA Technical Reports Server (NTRS)

O'Grady, E. Pearse; Young, Baek-Kyu

1991-01-01

An algorithm is presented for performing accurate, high-speed, floating-point function generation for univariate functions defined at arbitrary breakpoints. Rapid identification of the breakpoint interval, which includes the input argument, is shown to be the key operation in the algorithm. A hardware implementation which makes extensive use of read/write memories is used to illustrate the algorithm.

25 CFR 309.2 - What are the key definitions for purposes of the Act?

Code of Federal Regulations, 2011 CFR

2011-04-01

... “made by an Indian” means that an Indian has provided the artistic or craft work labor necessary to implement an artistic design through a substantial transformation of materials to produce the art or craft... Indian artistic or craft work labor; (v) Industrial products, which for this purpose are defined as goods...

Getting into Flow in the Arts Classroom: Research Findings and Implications for Practice

ERIC Educational Resources Information Center

Mansour, Marianne; Martin, Andrew J.; Anderson, Michael; Gibson, Robyn

2017-01-01

Research has shown that participation in the arts at school and in the classroom has many academic and personal well-being benefits. Here we outline some of the key effects of arts participation, with particular focus on one of its psychological yields: "flow." We then define flow and describe its nine ingredients with particular…

Providing Effective Learner Support for Part-Time Learners. Research Report

ERIC Educational Resources Information Center

Barker, Philip; Crawley, Jim

2005-01-01

Learner support, defined as the strategies which empower learners to establish and fulfill their learning, career and personal potential, continues to be a key issue in current thinking in the post-16 education sector. An earlier project report from the West Country Learning and Skills Research Network (WCLSRN) showed that part-time learners were…

User and System-Based Quality Criteria for Evaluating Information Resources and Services Available from Federal Websites: Final Report.

ERIC Educational Resources Information Center

Wyman, Steven K.; And Others

This exploratory study establishes analytical tools (based on both technical criteria and user feedback) by which federal Web site administrators may assess the quality of their websites. The study combined qualitative and quantitative data collection techniques to achieve the following objectives: (1) identify and define key issues regarding…

Globalisation, Geography Education and the Curriculum: What Are the Challenges for Curriculum Makers in Geography?

ERIC Educational Resources Information Center

Butt, Graham

2011-01-01

The forces of globalisation affect the lives of everybody on the planet--but defining the concept of globalisation, and its appropriate place within the school curriculum, still proves problematic. This article engages with three key issues: our understanding and conceptualisation of globalisation; the impacts of globalisation on education; and…

Lifestyles of the Student Leader: Making Decisions Based on the C.O.R.E.

ERIC Educational Resources Information Center

Hart, Falicia; Kean, Andy

1996-01-01

Key characteristics of an effective college student leader are defined: consistency in word and action; ownership of responsibility for actions and leadership position; development of healthy relationships with friends, coworkers, mentors, and mentees; and ethical decision making. It is argued that leadership is a full-time job and that student…

Collaboration The Key To: Defining Entry Level Competencies for Public Child Welfare Workers Serving Indian Communities.

ERIC Educational Resources Information Center

Gonzalez-Santin, Edwin; And Others

The rural environment in which most Indian tribal human service personnel work impedes the access of paraprofessional staff to professional education programs that will enable them to expand their theoretical knowledge, enhance their practical skills, and advance their careers. Each day, child welfare workers encounter complex tasks that require…

Evaluation of whole mount in situ hybridization as a tool for pathway-based toxicological research in early-life stage fathead minnows (poster)

EPA Science Inventory

Early-life stage fish can be more sensitive to chemical exposure than mature, adult fish. Therefore, defining adverse outcome pathways (AOPs) relevant to early-life stages is critical for linking perturbations of key events during fish development to potential adverse outcomes of...

A Service for Emotion Management: Turkish Version of the Adolescent Anger Rating Scale (AARS)

ERIC Educational Resources Information Center

Aslan, A. Esra; Sevincler-Togan, Seyhan

2009-01-01

An individual's activities are closely related with his/her communication abilities. One's awareness of his feelings and needs and to what extend he can control such feelings are the key factors which effect communication abilities. Webster (1996) defines anger as, "a strong emotion; a feeling that is oriented toward some real or supposed…

Where is the USA Corn Belt, and how is it changing?

USDA-ARS?s Scientific Manuscript database

The “Corn Belt” is a commonly used term, but often referenced as a vaguely defined region in the Midwest USA. A few key studies have delineated synoptic maps of the Corn Belt boundaries going back to the early 20th century, but a modern flexible and accessible framework for mapping the Corn Belt in ...

Earth and ocean modeling

NASA Technical Reports Server (NTRS)

Knezovich, F. M.

1976-01-01

A modular structured system of computer programs is presented utilizing earth and ocean dynamical data keyed to finitely defined parameters. The model is an assemblage of mathematical algorithms with an inherent capability of maturation with progressive improvements in observational data frequencies, accuracies and scopes. The Eom in its present state is a first-order approach to a geophysical model of the earth's dynamics.

European Adult Education Yesterday and Today: Some Questions Worth Pondering.

ERIC Educational Resources Information Center

Carlson, Robert A.

Key government advisers in Europe today are asking what is so important about this so-called "higher life" that it should be allowed to stand in the way of more "relevant," more "appropriate" adult education--adult education that meets the "real needs" of the people, needs that are defined almost exclusively by the planners as economic and…

Exploring Australian Undergraduate Pre-Registration Nursing Curricula: Where Do Science Subjects Fit?

ERIC Educational Resources Information Center

Logan, Patricia A.; Angel, Lyndall

2014-01-01

Despite several attempts to define what foundational science is required by and for the nursing profession, uncertainty has long existed in this area. Several attempts have been undertaken to elicit the appropriate level and depth of foundational science with the only clear result being that science has been recognised as key to good practice. The…

A Collaborative Approach to Defining the Usefulness of Impact: Lessons from a Knowledge Exchange Project Involving Academics and Social Work Practitioners

ERIC Educational Resources Information Center

Wilkinson, Heather; Gallagher, Michael; Smith, Mark

2012-01-01

This paper reports on a knowledge exchange project involving academics and practitioners in six local authority social work departments. It contributes to recent debates about the coproduction of knowledge, presenting findings in three key areas: the importance of relationships for knowledge exchange; "what works" for practitioners…

Addressing Student Debt: A New Post Secondary Learning Support System

ERIC Educational Resources Information Center

Association of Canadian Community Colleges, 2001

2001-01-01

Access and affordability are bountiful concepts and key words used by policy makers in defining the role of post-secondary education and training in Canada. However, these words have not translated into action for many learners due to student debt. Incurred from high tuition fees, costly and complex payback schemes and under-funding, chronic…

Technical Note: Field-observed angles of repose for stored grain in the United States

USDA-ARS?s Scientific Manuscript database

Bulk grain angle of repose (AoR) is a key parameter for inventorying grain, predicting flow characteristics, and designing bins and grain handling systems. The AoR is defined for two cases, piling (dynamic) or emptying (static), and usually varies with grain type. The objective of this study was to ...

Quantifying falsifiability of scientific theories

NASA Astrophysics Data System (ADS)

Nemenman, Ilya

I argue that the notion of falsifiability, a key concept in defining a valid scientific theory, can be quantified using Bayesian Model Selection, which is a standard tool in modern statistics. This relates falsifiability to the quantitative version of the statistical Occam's razor, and allows transforming some long-running arguments about validity of scientific theories from philosophical discussions to rigorous mathematical calculations.

Strategic Planning in 2005-2007: Not Your Daddy's Big Thick Binder!

ERIC Educational Resources Information Center

Burnham, Peter F.

2007-01-01

Effective strategic planning for community colleges contains four key elements: (1) It must be mission driven; (2) It must be integrated with capability and resources; (3) It must define measurable standards for determining outcomes; and (4) It must be transparent in its intent and strategic goals to all levels of the organization. Using a…

Linking Shared Organisational Context and Relational Capital through Unlearning: An Initial Empirical Investigation in SMEs

ERIC Educational Resources Information Center

Cegarra-Navarro, Juan G.; Dewhurst, Frank W.

2006-01-01

Purpose: The environment provided by an organisation to facilitate learning and create knowledge has been defined as the shared organisational context. The value to an organisation of knowledge created by the shared organisational context is called intellectual capital, of which one key component is relational capital. The purpose of this paper is…

The impact of patient and public involvement on UK NHS health care: a systematic review.

PubMed

Mockford, Carole; Staniszewska, Sophie; Griffiths, Frances; Herron-Marx, Sandra

2012-02-01

Patient and public involvement (PPI) has become an integral part of health care with its emphasis on including and empowering individuals and communities in the shaping of health and social care services. The aims of this study were to identify the impact of PPI on UK National Health Service (NHS) healthcare services and to identify the economic cost. It also examined how PPI is being defined, theorized and conceptualized, and how the impact of PPI is captured or measured. Seventeen key online databases and websites were searched, e.g. Medline and the King's Fund. UK studies from 1997 to 2009 which included service user involvement in NHS healthcare services. Date extraction Key themes were identified and a narrative analysis was undertaken. The review indicates that PPI has a range of impacts on healthcare services. There is little evidence of any economic analysis of the costs involved. A key limitation of the PPI evidence base is the poor quality of reporting impact. Few studies define PPI, there is little theoretical underpinning or conceptualization reported, there is an absence of robust measurement of impact and descriptive evidence lacked detail. There is a need for significant development of the PPI evidence base particularly around guidance for the reporting of user activity and impact. The evidence base needs to be significantly strengthened to ensure the full impact of involving service users in NHS healthcare services is fully understood.

[How staff perceives head nurses' leadership: a qualitative study].

PubMed

Morsiani, Giuliana; Bagnasco, Annamaria; Catania, Gianluca; Aleo, Giuseppe; Zanini, Milko; Sasso, Loredana

2017-01-01

The leadership style of the head nurses plays a crucial role in ensuring a work environment that fosters high quality nursing care. Their role involves a range of activities that constantly change, and is therefore difficult to describe. In fact, we do not have a fixed set of characteristics to define the 'ideal candidate'. To understand how staff defines the key leadership characteristics of the ideal head nurse in charge of a hospital ward. Between April-July 2015, 27 nurses were selected from the departments of general medicine in five hospitals. Three focus groups were conducted to identify the key leadership characteristics of an ideal head nurse. The ideal leadership characteristics are expressed through actions of staff empowerment, management skills, and use of coping strategies. All these categories require that a leader should be strongly determined, resourceful, enthusiastic, and willing to be a leader. When balancing 'what you give and receive', the main difficulty of being a leader is to be sufficiently determined to avoid exhaustion, which leads to emotional disengagement and consequently the loss of the leadership role. The level of determination of a head nurse, just like any source of energy, may sway. Therefore, it is important to recognize the signs of exhaustion and identify the strategy to rekindle determination. Sharing one's vision with others and job rotation could be used as strategies to recharge a leader's levels of energy, and meet the expectations linked to the leader's role. KEY WORDS: nurse manager, leadership style, determination, job rotation, vision.

Class D Management Implementation Approach of the First Orbital Mission of the Earth Venture Series

NASA Technical Reports Server (NTRS)

Wells, James E.; Scherrer, John; Law, Richard; Bonniksen, Chris

2013-01-01

A key element of the National Research Council's Earth Science and Applications Decadal Survey called for the creation of the Venture Class line of low-cost research and application missions within NASA (National Aeronautics and Space Administration). One key component of the architecture chosen by NASA within the Earth Venture line is a series of self-contained stand-alone spaceflight science missions called "EV-Mission". The first mission chosen for this competitively selected, cost and schedule capped, Principal Investigator-led opportunity is the CYclone Global Navigation Satellite System (CYGNSS). As specified in the defining Announcement of Opportunity, the Principal Investigator is held responsible for successfully achieving the science objectives of the selected mission and the management approach that he/she chooses to obtain those results has a significant amount of freedom as long as it meets the intent of key NASA guidance like NPR 7120.5 and 7123. CYGNSS is classified under NPR 7120.5E guidance as a Category 3 (low priority, low cost) mission and carries a Class D risk classification (low priority, high risk) per NPR 8705.4. As defined in the NPR guidance, Class D risk classification allows for a relatively broad range of implementation strategies. The management approach that will be utilized on CYGNSS is a streamlined implementation that starts with a higher risk tolerance posture at NASA and that philosophy flows all the way down to the individual part level.

A Rationally Designed Agonist Defines Subfamily IIIA Abscisic Acid Receptors As Critical Targets for Manipulating Transpiration.

PubMed

Vaidya, Aditya S; Peterson, Francis C; Yarmolinsky, Dmitry; Merilo, Ebe; Verstraeten, Inge; Park, Sang-Youl; Elzinga, Dezi; Kaundal, Amita; Helander, Jonathan; Lozano-Juste, Jorge; Otani, Masato; Wu, Kevin; Jensen, Davin R; Kollist, Hannes; Volkman, Brian F; Cutler, Sean R

2017-11-17

Increasing drought and diminishing freshwater supplies have stimulated interest in developing small molecules that can be used to control transpiration. Receptors for the plant hormone abscisic acid (ABA) have emerged as key targets for this application, because ABA controls the apertures of stomata, which in turn regulate transpiration. Here, we describe the rational design of cyanabactin, an ABA receptor agonist that preferentially activates Pyrabactin Resistance 1 (PYR1) with low nanomolar potency. A 1.63 Å X-ray crystallographic structure of cyanabactin in complex with PYR1 illustrates that cyanabactin's arylnitrile mimics ABA's cyclohexenone oxygen and engages the tryptophan lock, a key component required to stabilize activated receptors. Further, its sulfonamide and 4-methylbenzyl substructures mimic ABA's carboxylate and C6 methyl groups, respectively. Isothermal titration calorimetry measurements show that cyanabactin's compact structure provides ready access to high ligand efficiency on a relatively simple scaffold. Cyanabactin treatments reduce Arabidopsis whole-plant stomatal conductance and activate multiple ABA responses, demonstrating that its in vitro potency translates to ABA-like activity in vivo. Genetic analyses show that the effects of cyanabactin, and the previously identified agonist quinabactin, can be abolished by the genetic removal of PYR1 and PYL1, which form subclade A within the dimeric subfamily III receptors. Thus, cyanabactin is a potent and selective agonist with a wide spectrum of ABA-like activities that defines subfamily IIIA receptors as key target sites for manipulating transpiration.

A technological infrastructure to sustain Internetworked Enterprises

NASA Astrophysics Data System (ADS)

La Mattina, Ernesto; Savarino, Vincenzo; Vicari, Claudia; Storelli, Davide; Bianchini, Devis

In the Web 3.0 scenario, where information and services are connected by means of their semantics, organizations can improve their competitive advantage by publishing their business and service descriptions. In this scenario, Semantic Peer to Peer (P2P) can play a key role in defining dynamic and highly reconfigurable infrastructures. Organizations can share knowledge and services, using this infrastructure to move towards value networks, an emerging organizational model characterized by fluid boundaries and complex relationships. This chapter collects and defines the technological requirements and architecture of a modular and multi-Layer Peer to Peer infrastructure for SOA-based applications. This technological infrastructure, based on the combination of Semantic Web and P2P technologies, is intended to sustain Internetworked Enterprise configurations, defining a distributed registry and enabling more expressive queries and efficient routing mechanisms. The following sections focus on the overall architecture, while describing the layers that form it.

The evolution of process-based hydrologic models: historical challenges and the collective quest for physical realism

DOE Office of Scientific and Technical Information (OSTI.GOV)

Clark, Martyn P.; Bierkens, Marc F. P.; Samaniego, Luis

The diversity in hydrologic models has historically led to great controversy on the correct approach to process-based hydrologic modeling, with debates centered on the adequacy of process parameterizations, data limitations and uncertainty, and computational constraints on model analysis. Here, we revisit key modeling challenges on requirements to (1) define suitable model equations, (2) define adequate model parameters, and (3) cope with limitations in computing power. We outline the historical modeling challenges, provide examples of modeling advances that address these challenges, and define outstanding research needs. We also illustrate how modeling advances have been made by groups using models of different type and complexity,more » and we argue for the need to more effectively use our diversity of modeling approaches in order to advance our collective quest for physically realistic hydrologic models.« less

Defining and Assessing Public Health Functions: A Global Analysis.

PubMed

Martin-Moreno, Jose M; Harris, Meggan; Jakubowski, Elke; Kluge, Hans

2016-01-01

Given the broad scope and intersectoral nature of public health structures and practices, there are inherent difficulties in defining which services fall under the public health remit and in assessing their capacity and performance. The aim of this study is to analyze how public health functions and practice have been defined and operationalized in different countries and regions around the world, with a specific focus on assessment tools that have been developed to evaluate the performance of essential public health functions, services, and operations. Our review has identified nearly 100 countries that have carried out assessments, using diverse analytical and methodological approaches. The assessment processes have evolved quite differently according to administrative arrangements and resource availability, but some key contextual factors emerge that seem to favor policy-oriented follow-up. These include local ownership of the assessment process, policymakers' commitment to reform, and expert technical advice for implementation.

The evolution of process-based hydrologic models: historical challenges and the collective quest for physical realism

DOE PAGES

Clark, Martyn P.; Bierkens, Marc F. P.; Samaniego, Luis; ...

2017-07-11

The diversity in hydrologic models has historically led to great controversy on the correct approach to process-based hydrologic modeling, with debates centered on the adequacy of process parameterizations, data limitations and uncertainty, and computational constraints on model analysis. Here, we revisit key modeling challenges on requirements to (1) define suitable model equations, (2) define adequate model parameters, and (3) cope with limitations in computing power. We outline the historical modeling challenges, provide examples of modeling advances that address these challenges, and define outstanding research needs. We also illustrate how modeling advances have been made by groups using models of different type and complexity,more » and we argue for the need to more effectively use our diversity of modeling approaches in order to advance our collective quest for physically realistic hydrologic models.« less

'If she is a good woman …' and 'to be a real man …': gender, risk and access to HIV services among key populations in Tajikistan.

PubMed

King, Elizabeth J; Maksymenko, Kateryna M; Almodovar-Diaz, Yadira; Johnson, Sarah

2016-01-01

The HIV epidemic continues to grow in Tajikistan, especially among people who inject drugs, sex workers, men who have sex with men and incarcerated populations. Despite their susceptibility to HIV, members of these groups do not always have access to HIV prevention, testing and treatment. The purpose of this study was to identify and understand the gender constraints in accessing HIV services for key populations in Tajikistan. Using focus-group discussions and key-informant interviews the assessment team collected information from members of key populations and those who work with them. Several themes emerged from the data, including: low levels of HIV knowledge, gender constraints to condom use and safer drug use, gender constraints limit HIV testing opportunities, gender-based violence, stigma and discrimination, and the lack of female spaces in the HIV response. The results of this study show that there are well-defined gender norms in Tajikistan, and these gender norms influence key populations' access to HIV services. Addressing these gender constraints may offer opportunities for more equitable access to HIV services in Tajikistan.

Dynamite fishing in Tanzania.

PubMed

Slade, Lorna M; Kalangahe, Baraka

2015-12-30

Fishing using explosives is common in Tanzanian waters; it is considered to be more widely practised now than at any other point in history. Mwambao Coastal Community Network, a Tanzanian NGO carried out a multi-stakeholder consultation in April 2014 initiated through the concern of private investors and tourism operators. Consultations were held with villagers, fisheries officers, government officers, hoteliers, dive operators, fish processors, NGOs and other key individuals, and shed some light on key factors enabling this practice to flourish. Key areas identified for attention include engendering political will at all levels, upholding of the law through a non-corrupt enforcement and judicial system, and defining clear roles and responsibilities for monitoring and surveillance. The work identified other successful initiatives which have tackled this pervasive practice including projects that build local capacity for marine governance, villages that have declared themselves intolerant of blast-fishing, and private-public partnerships for patrol and protection. Copyright © 2015 Elsevier B.V. All rights reserved.

Investigation of a high speed data handling system for use with multispectral aircraft scanners

NASA Technical Reports Server (NTRS)

Kelly, W. L.; Meredith, B. D.

1978-01-01

A buffer memory data handling technique for use with multispectral aircraft scanners is presented which allows digital data generated at high data rates to be recorded on magnetic tape. A digital memory is used to temporarily store the data for subsequent recording at slower rates during the passive time of the scan line, thereby increasing the maximum data rate recording capability over real-time recording. Three possible implementations are described and the maximum data rate capability is defined in terms of the speed capability of the key hardware components. The maximum data rates can be used to define the maximum ground resolution achievable by a multispectral aircraft scanner using conventional data handling techniques.

Shapes, Proportions, and Variations in Breast Aesthetic Ideals: The Definition of Breast Beauty, Analysis, and Surgical Practice.

PubMed

Mallucci, Patrick; Branford, Olivier Alexandre

2015-10-01

There are few objective analyses in the plastic surgical literature to define an aesthetically pleasing template for breast shape and proportion. The authors previously identified key objective parameters that define breast aesthetic ideals in 2 studies: an observational analysis of 100 models with natural breasts, and a population analysis with 1315 respondents. From these data a simple yet reproducible formula for surgical planning in breast augmentation has been developed to consistently achieve beautiful breasts, namely the ICE principle. This article proposes that this principle be used as the basis for design in aesthetic breast surgery. Copyright © 2015 Elsevier Inc. All rights reserved.

The symmetry of single-molecule conduction.

PubMed

Solomon, Gemma C; Gagliardi, Alessio; Pecchia, Alessandro; Frauenheim, Thomas; Di Carlo, Aldo; Reimers, Jeffrey R; Hush, Noel S

2006-11-14

We introduce the conductance point group which defines the symmetry of single-molecule conduction within the nonequilibrium Green's function formalism. It is shown, either rigorously or to within a very good approximation, to correspond to a molecular-conductance point group defined purely in terms of the properties of the conducting molecule. This enables single-molecule conductivity to be described in terms of key qualitative chemical descriptors that are independent of the nature of the molecule-conductor interfaces. We apply this to demonstrate how symmetry controls the conduction through 1,4-benzenedithiol chemisorbed to gold electrodes as an example system, listing also the molecular-conductance point groups for a range of molecules commonly used in molecular electronics research.

Understanding gender roles in teen pregnancy prevention among American Indian youth.

PubMed

Hanson, Jessica D; McMahon, Tracey R; Griese, Emily R; Kenyon, DenYelle Baete

2014-11-01

To examine the impact of gender norms on American Indian (AI) adolescents' sexual health behavior. The project collected qualitative data at a reservation site and an urban site through 24 focus groups and 20 key informant interviews. The reasons that AI youth choose to abstain or engage in sexual intercourse and utilize contraception vary based on gender ideologies defined by the adolescent's environment. These include social expectations from family and peers, defined roles within relationships, and gender empowerment gaps. Gender ideology plays a large role in decisions about contraception and sexual activity for AI adolescents, and it is vital to include redefinitions of gender norms within AI teen pregnancy prevention program.

Objective comparison of particle tracking methods

PubMed Central

Chenouard, Nicolas; Smal, Ihor; de Chaumont, Fabrice; Maška, Martin; Sbalzarini, Ivo F.; Gong, Yuanhao; Cardinale, Janick; Carthel, Craig; Coraluppi, Stefano; Winter, Mark; Cohen, Andrew R.; Godinez, William J.; Rohr, Karl; Kalaidzidis, Yannis; Liang, Liang; Duncan, James; Shen, Hongying; Xu, Yingke; Magnusson, Klas E. G.; Jaldén, Joakim; Blau, Helen M.; Paul-Gilloteaux, Perrine; Roudot, Philippe; Kervrann, Charles; Waharte, François; Tinevez, Jean-Yves; Shorte, Spencer L.; Willemse, Joost; Celler, Katherine; van Wezel, Gilles P.; Dan, Han-Wei; Tsai, Yuh-Show; de Solórzano, Carlos Ortiz; Olivo-Marin, Jean-Christophe; Meijering, Erik

2014-01-01

Particle tracking is of key importance for quantitative analysis of intracellular dynamic processes from time-lapse microscopy image data. Since manually detecting and following large numbers of individual particles is not feasible, automated computational methods have been developed for these tasks by many groups. Aiming to perform an objective comparison of methods, we gathered the community and organized, for the first time, an open competition, in which participating teams applied their own methods independently to a commonly defined data set including diverse scenarios. Performance was assessed using commonly defined measures. Although no single method performed best across all scenarios, the results revealed clear differences between the various approaches, leading to important practical conclusions for users and developers. PMID:24441936

Optimization and planning of operating theatre activities: an original definition of pathways and process modeling.

PubMed

Barbagallo, Simone; Corradi, Luca; de Ville de Goyet, Jean; Iannucci, Marina; Porro, Ivan; Rosso, Nicola; Tanfani, Elena; Testi, Angela

2015-05-17

The Operating Room (OR) is a key resource of all major hospitals, but it also accounts for up 40% of resource costs. Improving cost effectiveness, while maintaining a quality of care, is a universal objective. These goals imply an optimization of planning and a scheduling of the activities involved. This is highly challenging due to the inherent variable and unpredictable nature of surgery. A Business Process Modeling Notation (BPMN 2.0) was used for the representation of the "OR Process" (being defined as the sequence of all of the elementary steps between "patient ready for surgery" to "patient operated upon") as a general pathway ("path"). The path was then both further standardized as much as possible and, at the same time, keeping all of the key-elements that would allow one to address or define the other steps of planning, and the inherent and wide variability in terms of patient specificity. The path was used to schedule OR activity, room-by-room, and day-by-day, feeding the process from a "waiting list database" and using a mathematical optimization model with the objective of ending up in an optimized planning. The OR process was defined with special attention paid to flows, timing and resource involvement. Standardization involved a dynamics operation and defined an expected operating time for each operation. The optimization model has been implemented and tested on real clinical data. The comparison of the results reported with the real data, shows that by using the optimization model, allows for the scheduling of about 30% more patients than in actual practice, as well as to better exploit the OR efficiency, increasing the average operating room utilization rate up to 20%. The optimization of OR activity planning is essential in order to manage the hospital's waiting list. Optimal planning is facilitated by defining the operation as a standard pathway where all variables are taken into account. By allowing a precise scheduling, it feeds the process of planning and, further up-stream, the management of a waiting list in an interactive and bi-directional dynamic process.

Centrifuge technique consistently overestimates vulnerability to water-stress induced cavitation in grapevines as confirmed with high resolution computed tomography

USDA-ARS?s Scientific Manuscript database

Vulnerability to cavitation is a key variable defining the limits to drought resistance in woody plants (e.g. Kursar et al., 2009). This trait is typically assessed by a vulnerability curve, which can be generated by a range of methods including dehydration (Sperry et al., 1988) air injection (Cocha...

Elementary School Students' Science Talk Ability in Inquiry-Oriented Settings in Taiwan: Test Development, Verification, and Performance Benchmarks

ERIC Educational Resources Information Center

Lin, Sheau-Wen; Liu, Yu; Chen, Shin-Feng; Wang, Jing-Ru; Kao, Huey-Lien

2016-01-01

The purpose of this study was to develop a computer-based measure of elementary students' science talk and to report students' benchmarks. The development procedure had three steps: defining the framework of the test, collecting and identifying key reference sets of science talk, and developing and verifying the science talk instrument. The…

Mapping a Research Agenda for Home Care Safety: Perspectives from Researchers, Providers, and Decision Makers

ERIC Educational Resources Information Center

Macdonald, Marilyn; Lang, Ariella; MacDonald, Jo-Anne

2011-01-01

The purpose of this qualitative interpretive design was to explore the perspectives of researchers, health care providers, policy makers, and decision makers on key risks, concerns, and emerging issues related to home care safety that would inform a line of research inquiry. Defining safety specifically in this home care context has yet to be…

The Development of Technology Enhanced Learning: Findings from a 2008 Survey of UK Higher Education Institutions

ERIC Educational Resources Information Center

Jenkins, Martin; Browne, Tom; Walker, Richard; Hewitt, Roger

2011-01-01

This article summarises the key findings from a UK survey of higher education institutions, focusing on the development of technology enhanced learning (TEL). TEL is defined as any online facility or system that directly supports learning and teaching. The 2008 survey builds upon previous UCISA surveys conducted in 2001, 2003 and 2005 and for…

Competency-Based Degree Programs in the U.S.: Postsecondary Credentials for Measurable Student Learning and Performance

ERIC Educational Resources Information Center

Klein-Collins, Rebecca

2012-01-01

Today the U.S. higher education system is facing a crisis regarding its perceived quality. One model for improving quality is competency-based education, in which an institution clearly defines the specific competencies expected of its graduates. A key challenge is how to help more people, particularly adults, succeed at the post¬secondary level…

Talking Up and Justifying Organisation: The Creation and Control of Knowledge about Being Organised. Studies in Educational Administration Number 41.

ERIC Educational Resources Information Center

Macpherson, R. J. S.

This paper reviews some key ideas that have emerged from recent research into administrative practices in education and their relationship to organizational culture. "Culture" is defined as a system of knowledge and conceptions that members of an organization use for giving meaning to and coping with problems that they experience. The…

78 FR 4307 - Current Good Manufacturing Practice Requirements for Combination Products

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-22

.... Rationale for the Rulemaking B. The Proposed Rule C. The Final Rule II. Comments on the Proposed Rule A. General B. What is the scope of this subpart? (Sec. 4.1) C. How does FDA define key terms and phrases in... Act (the PHS Act) (42 U.S.C. 262). All biological products regulated under the PHS Act meet the...

Ten commandments for medical practice harmony.

PubMed

Pfifferling, John-Henry

2011-01-01

Medical practice divorce is endemic and as personally harmful as marital divorce Using lessons from crisis interventions in medical practices, the author suggests a few essential prescriptions for ensuring high morale among physicians as well as reducing practice divorce. A key ingredient among collegial, healthy medical practices is insight into and use of one's partner's energizers and exhausters as well as defining and affirming professionalism.

Coordination Costs for School-Located Influenza Vaccination Clinics, Maine, 2009 H1N1 Pandemic

ERIC Educational Resources Information Center

Asay, Garrett R. Beeler; Cho, Bo-Hyun; Lorick, Suchita A.; Tipton, Meredith L.; Dube, Nancy L.; Messonnier, Mark L.

2012-01-01

School nurses played a key role in Maine's school-located influenza vaccination (SLV) clinics during the 2009-2010 pandemic season. The objective of this study was to determine, from the school district perspective, the labor hours and costs associated with outside-clinic coordination activities (OCA). The authors defined OCA as labor hours spent…

Enabling the Future: Linking Science and Technology to Societal Goals. A Report.

ERIC Educational Resources Information Center

Carnegie Commission on Science, Technology, and Government, New York, NY.

This report seeks ways to improve the knowledge, understanding, and information available to the federal government on the long-term nature of the science and technology (S&T) enterprise as it relates to societal goals. The recommendations focus on a few key issues: improving the national capacity to define and revise long-term S&T goals; linking…

Co-Teaching to Support Early Adolescents' Writing Development in an Inclusive Summer Enrichment Program

ERIC Educational Resources Information Center

Chandler-Olcott, Kelly

2017-01-01

Co-teaching, defined by Friend and Cook (2013) as substantive instruction by two or more professionals of a diverse group of learners in a shared space, has long been a key feature of middle level instruction. This article reports on a four-year formative experiment (Reinking & Bradley, 2008) intended to generate insights to guide teachers'…

Using University Students' L1 as a Resource: Translanguaging in a Puerto Rican ESL Classroom

ERIC Educational Resources Information Center

Carroll, Kevin S.; Sambolín Morales, Astrid N.

2016-01-01

Framed within Ruiz's language-as-resource orientation, this article uses data from a college ESL classroom where a translanguaging approach was used for the teaching of a novel. After defining key terms, the article describes the linguistic context of higher education in Puerto Rico and its influence on one instructor's Basic English course. Using…

Assessing the Rigor of HS Curriculum in Admissions Decisions: A Functional Method, Plus Practical Advising for Prospective Students and High School Counselors

ERIC Educational Resources Information Center

Micceri, Theodore; Brigman, Leellen; Spatig, Robert

2009-01-01

An extensive, internally cross-validated analytical study using nested (within academic disciplines) Multilevel Modeling (MLM) on 4,560 students identified functional criteria for defining high school curriculum rigor and further determined which measures could best be used to help guide decision making for marginal applicants. The key outcome…

The Indicator Performance Estimate (IPE) Approach to Defining Acceptable Conditions in Wilderness

Treesearch

Steven Hollenhorst; Lisa Stull-Gardner

1992-01-01

Using data from a study conducted in the Cranberry Wilderness area, this paper describes how the Importance-Performance approach can be used to prioritize wilderness indicators and determine how much change from the pristine is acceptable. The approach uses two key types of information: (1) indicator importance, or visitor opinion as to which wilderness indicators have...

Breeding dispersal of Mexican Spotted Owls in the Sacramento Mountains, New Mexico

Treesearch

Joseph L. Ganey; Darrell L. Apprill; Todd A. Rawlinson; Sean C. Kyle; Ryan S. Jonnes; James P. Ward

2014-01-01

Dispersal is a key process influencing population dynamics and gene flow in species. Despite this, little is known about breeding dispersal in threatened Mexican Spotted Owls (Strix occidentalis lucida), here defined as movement of a non-juvenile owl between territories where it had the opportunity to breed. We observed 28 cases of breeding dispersal during a study of...

Teaching Aids and Work with Models in E-Learning Environments

ERIC Educational Resources Information Center

Jancaríková, Katerina; Jancarík, Antonín

2017-01-01

PISA study has defined several key areas to be paid attention to by teachers. One of these areas is work with models. The term model can be understood very broadly, it can refer to a drawing of a chemical reaction, a plastic model, a permanent mount (taxidermy) to advanced 3D projections. Teachers are no longer confined to teaching materials and…

Speed-Accuracy Tradeoffs in Speech Production

DTIC Science & Technology

2017-06-01

imaging data of speech production. A theoretical framework for considering Fitts’ law in the domain of speech production is elucidated. Methodological ...articulatory kinematics conform to Fitts’ law. A second, associated goal is to address the methodological challenges inherent in performing Fitts-style...analysis on rtMRI data of speech production. Methodological challenges include segmenting continuous speech into specific motor tasks, defining key

Profitability potential for Pinus taeda L. (loblolly pine) short-rotation bioenergy plantings in the southern USA

Treesearch

James H. Perdue; John A. Stanturf; Timothy M. Young; Xia Huang; Derek Dougherty; Michael Pigott; Zhimei Guo

2017-01-01

The use of renewable resources is important to the developing bioenergy economy and short rotation woody crops (SRWC) are key renewable feedstocks. A necessary step in advancing SRWC is defining regions suitable for SRWC commercial activities and assessing the relative economic viability among suitable regions. The goal of this study was to assess the potential...

When Five Words Are Not Enough: A Conceptual and Terminological Discussion of English as a Lingua Franca

ERIC Educational Resources Information Center

Friedrich, Patricia; Matsuda, Aya

2010-01-01

The goal of this article is to (re)define key terminology in the study of English as a lingua franca (ELF). Although the diverse perspectives and ideological standpoints represented in competing definitions of terms is appreciated, a critical conversation on definition and interpretation of ELF and other related concepts is crucial in providing a…

Towards the Improvement of the Student Experience of Assessment and Feedback in Construction Management Education

ERIC Educational Resources Information Center

Scott, Lloyd; Fortune, Chris

2013-01-01

It is widely accepted across Higher Education that assessment practices have a link with learning and a key factor in this link is formative assessment. Formative assessment is generally defined as taking place during a module/programme with the express purpose of improving and enhancing student learning. It is important to understand how…

Some Reflections on "Going beyond the Consensus View" of the Nature of Science in K-12 Science Education

ERIC Educational Resources Information Center

Berkovitz, Joseph

2017-01-01

Hodson and Wong (2017, this issue) argue that, though the nature of science (NOS) is now an established focus of school science education and a key element in defining scientific literacy, "the consensus view" of NOS misrepresents contemporary scientific practice. They then propose a number of alternative approaches to science curriculum…

From the Classroom to the Keyboard: How Seven Teachers Created Their Online Teacher Identities

ERIC Educational Resources Information Center

Richardson, Jennifer C.; Alsup, Janet

2015-01-01

Teacher identity is defined as a sense of teacher self that results from a productive combination of key personal and professional subjectivities or beliefs. Much empirical research has been done on the development of teacher identity in the K-12 arena, with a great deal of theoretical and philosophical scholarship about teaching at the college…

The Applications of Computers in Education in Developing Countries--with Specific Reference to the Cost-Effectiveness of Computer-Assisted Instruction.

ERIC Educational Resources Information Center

Lai, Kwok-Wing

Designed to examine the application and cost-effectiveness of computer-assisted instruction (CAI) for secondary education in developing countries, this document is divided into eight chapters. A general introduction defines the research problem, describes the research methodology, and provides definitions of key terms used throughout the paper.…

Effects of riparian zone buffer widths on vegetation diversity in southern Appalachian headwater catchments

Treesearch

Katherine J. Elliott; James M. Vose

2016-01-01

In mountainous areas such as the southern Appalachians USA, riparian zones are difficult to define. Vegetation is a commonly used riparian indicator and plays a key role in protecting water resources, but adequate knowledge of floristic responses to riparian disturbances is lacking. Our objective was to quantify changes in stand-level floristic diversity of...

Operational Suitability Guide. Volume 2. Templates

DTIC Science & Technology

1990-05-01

Intended mission, and the required technical and operational characteristics. The mission must be adequately defined and key hardware and software ...operational availability. With the use of fault-tolerant computer hardware and software , the system R&M will significantly improve end-to-end...should Include both hardware and software elements, as appropriate. Unique characteristics or unique support concepts should be Identified if they result

Mineral separation and recycle in a Controlled Ecological Life Support System (CELSS)

NASA Technical Reports Server (NTRS)

Ballou, E. V.

1982-01-01

The background of the mineral nutrition needs of plants are examined along with the applicability of mineral control and separation to a controlled ecological life support system (CELSS). Steps that may be taken in a program to analytically define and experimentally test key mineral control concepts in the nutritional and waste processing loops of a CELSS are delineated.

Going beyond the Consensus View: Broadening and Enriching the Scope of NOS-Oriented Curricula

ERIC Educational Resources Information Center

Hodson, Derek; Wong, Siu Ling

2017-01-01

Nature of science (NOS) is now a well-established focus of science education and a key element in defining scientific literacy. In recent years, a particular specification of NOS, often described as "the consensus view," has become very influential and has gained ready acceptance in many countries around the world as a template for…

Clinical evaluation of patients with patellofemoral disorders.

PubMed

Post, W R

1999-01-01

Accurate clinical evaluation of patients with patellofemoral disorders is the cornerstone of effective treatment. This article defines how a careful history and physical examination can direct strategies for nonoperative and operative management. A critical analysis of traditional methods of evaluation and a streamlined rational approach to clinical evaluation is presented. Key questions and important physical findings that affect treatment decisions are emphasized.